ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A01 compound treatment 0.443 0.196 10.52 10.5192 1.0 1911149 Bionet2_000001 C/C(=N\O)/c1ccc(cc1)n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A02 compound treatment 0.426 0.179 9.61 9.6057 1.0 1911150 Bionet2_000002 COC/1=CC(=O)O\C1=C/Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A03 compound treatment 0.293 0.0457 2.46 2.4585 1.0 1911151 Bionet2_000003 c1cn(cn1)c2ccc(cc2)c3nn[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A04 compound treatment 0.342 0.0948 5.09 5.0917 1.0 1667665 Bionet2_000004 CNc1ncc(s1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A05 compound treatment 0.243 -0.00425 -0.23 -0.2284 -1.0 1911152 Bionet2_000005 CS(=O)c1ccccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A06 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1156703 Bionet2_000006 O=C(Nc1cc2C(=O)CCCc2oc1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A07 compound treatment 0.274 0.0267 1.44 1.4375 1.0 1911153 Bionet2_000007 Clc1ccc(N/C=C/2\C(=O)ON=C2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A08 compound treatment 0.288 0.0408 2.19 2.1898 1.0 1911154 Bionet2_000008 FC(F)(F)c1cc(Cl)nc(n1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A09 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1911155 Bionet2_000009 CN(C)c1nnnn1c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A10 compound treatment 0.242 -0.00525 -0.28 -0.2821 -1.0 1365852 Bionet2_000010 CN(C)C(=O)c1cn(c2ccccc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A11 compound treatment 0.279 0.0318 1.71 1.7062 1.0 1911156 Bionet2_000011 Fc1ccc(Oc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A12 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1911157 Bionet2_000012 Oc1ccnn1c2cccc(Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A13 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1911158 Bionet2_000013 Oc1ncn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A14 compound treatment 0.254 0.00675 0.36 0.3627 1.0 1911159 Bionet2_000014 Cn1nc(c(/C=N/O)c1Sc2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A15 compound treatment 0.289 0.0418 2.24 2.2436 1.0 1412053 Bionet2_000015 O=C1CSCN1c2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A16 compound treatment 0.245 -0.00225 -0.12 -0.1209 -1.0 1911160 Bionet2_000016 On1c(nc2ncccc12)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A17 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1297348 Bionet2_000017 NC(=O)c1cnn2c(ccnc12)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A18 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1185511 Bionet2_000018 Clc1cccc(c1)c2nnc3c4ccccc4ncn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A19 compound treatment 0.265 0.0177 0.95 0.9538 1.0 1911161 Bionet2_000019 O/N=C\c1coc2ccc(F)cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A20 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1211383 Bionet2_000020 COC(=O)c1cc(cn1C)C(=O)c2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A21 compound treatment 0.249 0.00175 0.09 0.094 1.0 1144178 Bionet2_000021 NC(=C(C#N)C#N)COc1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A22 compound treatment 0.33 0.0828 4.45 4.4468 1.0 1911162 Bionet2_000022 CCOC(=O)c1csc(n1)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A23 mock treatment 0.232 -0.0153 -0.82 -0.8195 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 A24 mock treatment 0.252 0.00475 0.26 0.2553 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B01 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1368190 Bionet2_000023 Cc1cc(C)n2cc(c(C(=O)O)c2n1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B02 compound treatment 0.268 0.0208 1.12 1.1151 1.0 1319220 Bionet2_000024 CC1SCC(=O)N(C1=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B03 compound treatment 0.316 0.0688 3.69 3.6945 1.0 1406235 Bionet2_000025 Cc1ccc(cc1)S(=O)CCOc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B04 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1911163 Bionet2_000026 OC(=O)CC(=O)Oc1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B05 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1911164 Bionet2_000027 Cc1onc(c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B06 compound treatment 0.273 0.0257 1.38 1.3838 1.0 1911165 Bionet2_000028 COC(=O)C1=Cc2cc(Cl)ccc2OC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B07 compound treatment 0.254 0.00675 0.36 0.3627 1.0 1911166 Bionet2_000029 Cn1cccc1C(C#N)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B08 compound treatment 0.246 -0.00125 -0.07 -0.0672 -1.0 1911167 Bionet2_000030 COc1ccc(cc1)C(=O)CS(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B09 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1911168 Bionet2_000031 NC(=O)C1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B10 compound treatment 0.268 0.0208 1.12 1.1151 1.0 1724979 Bionet2_000032 Clc1ccccc1S(=O)(=O)CC(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B11 compound treatment 0.285 0.0377 2.03 2.0286 1.0 1458253 Bionet2_000033 CCCCC(=O)Nc1ccc(cc1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B12 compound treatment 0.272 0.0248 1.33 1.33 1.0 1911169 Bionet2_000034 ON=C1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B13 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1166529 Bionet2_000035 NC(=O)C1CN(Cc2ccccc2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B14 compound treatment 0.475 0.228 12.24 12.2388 1.0 1220452 Bionet2_000036 OC(=O)c1sccc1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B15 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1911170 Bionet2_000037 Clc1ccccc1C(C#N)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B16 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911171 Bionet2_000038 Cc1ccc(Cc2ccc(O)nn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B17 compound treatment 0.315 0.0678 3.64 3.6407 1.0 1911172 Bionet2_000039 FC(F)(F)c1cnc(N2CCC(=C(C#N)C#N)CC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B18 compound treatment 0.273 0.0257 1.38 1.3838 1.0 1911173 Bionet2_000040 OC(CS(=O)(=O)c1cccc(c1)C(F)(F)F)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B19 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1485959 Bionet2_000041 CCOC(=O)c1cnc2c(F)cc(F)cc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B20 compound treatment 0.314 0.0668 3.59 3.587 1.0 1911174 Bionet2_000042 Cn1c(CO)cnc1SCC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B21 compound treatment 0.289 0.0418 2.24 2.2436 1.0 1355918 Bionet2_000043 COc1ccc(cc1OC)c2c[nH]nc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B22 compound treatment 0.257 0.00975 0.52 0.5239 1.0 1618086 Bionet2_000044 NC(=O)c1cn(c2ccc(F)cc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B23 mock treatment 0.238 -0.00925 -0.5 -0.4971 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 B24 mock treatment 0.249 0.00175 0.09 0.094 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C01 compound treatment 0.478 0.231 12.4 12.4 1.0 1911175 Bionet2_000045 c1cc([nH]n1)c2ccc(cc2)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C02 compound treatment 0.501 0.254 13.64 13.636 1.0 1911176 Bionet2_000046 COC/1=CC(=O)O\C1=C/Nc2ccc(cc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C03 compound treatment 0.501 0.254 13.64 13.636 1.0 1911177 Bionet2_000047 COc1ccc(N/C=C\2/Sc3ccccc3NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C04 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1911178 Bionet2_000048 CNc1ncc(s1)C(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C05 compound treatment 0.354 0.107 5.74 5.7365 1.0 1911179 Bionet2_000049 [O-][n+]1ccccc1SC/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C06 compound treatment 0.274 0.0267 1.44 1.4375 1.0 1911180 Bionet2_000050 FC(F)(F)c1cc(NCc2ccccc2)nc(n1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C07 compound treatment 0.26 0.0127 0.69 0.6852 1.0 1226805 Bionet2_000051 C1CN(CCO1)c2n[nH]cc2c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C08 compound treatment 0.276 0.0288 1.54 1.545 1.0 1911181 Bionet2_000052 FC(F)(F)c1cc(c2ccc(Cl)nc2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C09 compound treatment 0.322 0.0747 4.02 4.0169 1.0 1531372 Bionet2_000053 CN(C)c1nnnn1Cc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C10 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1911182 Bionet2_000054 FC(F)(F)c1cccc(c1)C(=O)Oc2cccnc2I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C11 compound treatment 0.36 0.113 6.06 6.0589 1.0 1911183 Bionet2_000055 FC(F)(F)c1cccc(Sc2cnc3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C12 compound treatment 0.343 0.0958 5.15 5.1454 1.0 1458801 Bionet2_000056 C(Nc1nc2ccccc2n3cnnc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C13 compound treatment 0.268 0.0208 1.12 1.1151 1.0 1911184 Bionet2_000057 Fc1ccc(cc1)c2ccnc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C14 compound treatment 0.281 0.0338 1.81 1.8137 1.0 1911185 Bionet2_000058 FC(F)(F)c1cccc(c1)C(=O)Nc2cccn3ncnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C15 compound treatment 0.598 0.351 18.85 18.8486 1.0 1273428 Bionet2_000059 O=C(Cc1nc(=O)c2ccccc2s1)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C16 compound treatment 0.402 0.155 8.32 8.3159 1.0 1150160 Bionet2_000060 C(On1c(nc2ncccc12)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C17 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1428094 Bionet2_000061 Oc1cc(O)c2C(CC(=O)Oc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C18 compound treatment 0.318 0.0707 3.8 3.802 1.0 1261287 Bionet2_000062 Cc1ccc(cc1)c2nc3ccc(Cl)cc3n2OCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C19 compound treatment 0.28 0.0328 1.76 1.7599 1.0 1293084 Bionet2_000063 O=S(=O)(Cc1ccccc1)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C20 compound treatment 0.28 0.0328 1.76 1.7599 1.0 1613984 Bionet2_000064 Cn1cc(cc1C(=O)N)C(=O)c2cccc(Cl)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C21 compound treatment 0.263 0.0158 0.85 0.8464 1.0 1911186 Bionet2_000065 Cc1ccc(SC2=CCS(=O)(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C22 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1911187 Bionet2_000066 COC(=O)c1ccc(cc1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C23 mock treatment 0.253 0.00575 0.31 0.309 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 C24 mock treatment 0.254 0.00675 0.36 0.3627 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D01 compound treatment 0.241 -0.00625 -0.34 -0.3359 -1.0 1911188 Bionet2_000067 CN1OC(CO)CC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D02 compound treatment 0.257 0.00975 0.52 0.5239 1.0 1911189 Bionet2_000068 CC1SCC(=O)N(C1=O)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D03 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1271485 Bionet2_000069 CC(C)(C)c1ccc(CS(=O)(=O)CCOc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D04 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1047994 Bionet2_000070 OC(=O)CC(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D05 compound treatment 0.246 -0.00125 -0.07 -0.0672 -1.0 1911190 Bionet2_000071 FC(F)(F)c1cnc(c(Cl)c1)n2cncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D06 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1133831 Bionet2_000072 CC(C)(C#N)N1CCN(CC1)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D07 compound treatment 0.273 0.0257 1.38 1.3838 1.0 1911191 Bionet2_000073 FC(F)(F)c1cnc(C(C#N)c2cccs2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D08 compound treatment 0.276 0.0288 1.54 1.545 1.0 1911192 Bionet2_000074 CS(=O)(=O)CC(=O)c1ccc(Cl)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D09 compound treatment 0.273 0.0257 1.38 1.3838 1.0 1911193 Bionet2_000075 Clc1cc(Cl)cc(c1)C(=N)Nc2cccc(C#N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D10 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911194 Bionet2_000076 Fc1ccc(cc1F)n2nnnc2c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D11 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1479303 Bionet2_000077 CC(C)C(=O)Nc1ccc(cc1)N2CCN(CC2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D12 compound treatment 0.346 0.0988 5.31 5.3066 1.0 1911195 Bionet2_000078 CN(C(=O)CSCc1ccc(Cl)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D13 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1911196 Bionet2_000079 COC(=O)c1ccccc1CSC(=N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D14 compound treatment 0.241 -0.00625 -0.34 -0.3359 -1.0 1911197 Bionet2_000080 COC(=O)c1c(C)onc1c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D15 compound treatment 0.455 0.208 11.16 11.1641 1.0 1606801 Bionet2_000081 CC(Oc1ccc(Cl)cc1)c2ccc(C#N)c(O)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D16 compound treatment 0.503 0.256 13.74 13.7435 1.0 1911198 Bionet2_000082 Cc1ccc(Cc2ccc(Cl)nn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D17 compound treatment 0.261 0.0138 0.74 0.7389 1.0 1911199 Bionet2_000083 FC(F)(F)c1cccc(CN2C(=O)CSCC2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D18 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1911200 Bionet2_000084 Cc1cccc(C)c1NC(=O)CBr 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D19 compound treatment 0.266 0.0187 1.01 1.0076 1.0 1732141 Bionet2_000085 CCOC(=O)c1cnc2ccc(C)cc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D20 compound treatment 0.239 -0.00825 -0.44 -0.4433 -1.0 1610109 Bionet2_000086 CC1CN(CC(C)O1)C(=O)CS(=O)(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D21 compound treatment 0.287 0.0398 2.14 2.1361 1.0 1911201 Bionet2_000087 COc1ccc2cc(ccc2c1Br)c3nc(N)ncc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D22 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1911202 Bionet2_000088 Cc1onc(c1C(=O)N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D23 mock treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 D24 mock treatment 0.24 -0.00725 -0.39 -0.3896 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E01 compound treatment 0.507 0.26 13.96 13.9584 1.0 1911203 Bionet2_000089 O=C(Nc1ccccc1)n2ccc(n2)c3ccc(cc3)n4ccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E02 compound treatment 0.274 0.0267 1.44 1.4375 1.0 1911204 Bionet2_000090 Cc1nc(SCc2ccccc2)nc3CCCc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E03 compound treatment 0.47 0.223 11.97 11.9701 1.0 1911205 Bionet2_000091 FC(F)(F)c1cccc(N/C=C\2/Sc3ccccc3NC2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E04 compound treatment 0.413 0.166 8.91 8.9071 1.0 1911206 Bionet2_000092 Clc1ccc(cc1)c2cn3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E05 compound treatment 0.292 0.0447 2.4 2.4048 1.0 1911207 Bionet2_000093 Nc1ccccc1SC/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E06 compound treatment 0.251 0.00375 0.2 0.2015 1.0 1911208 Bionet2_000094 CCN(CC)c1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E07 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1243114 Bionet2_000095 CN(C)c1n[nH]cc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E08 compound treatment 0.271 0.0238 1.28 1.2763 1.0 1911209 Bionet2_000096 NNc1ccc2c(cc(nc2n1)C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E09 compound treatment 0.285 0.0377 2.03 2.0286 1.0 1911210 Bionet2_000097 Cc1ccc(cc1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E10 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1911211 Bionet2_000098 CC(=O)Oc1cccnc1I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E11 compound treatment 0.322 0.0747 4.02 4.0169 1.0 1911212 Bionet2_000099 O(c1ccccc1)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E12 compound treatment 0.291 0.0437 2.35 2.351 1.0 1911213 Bionet2_000100 NNc1nc2cc(Cl)ccc2nc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E13 compound treatment 0.372 0.125 6.7 6.7038 1.0 1149357 Bionet2_000101 O(c1ccccc1)c2ccc(cc2)c3ccnc4ncnn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E14 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911214 Bionet2_000102 C/[N+](=C/c1ccccc1)/[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E15 compound treatment 0.376 0.129 6.92 6.9188 1.0 1911215 Bionet2_000103 O=C(CC#N)Nc1cccnc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E16 compound treatment 0.29 0.0428 2.3 2.2973 1.0 1294474 Bionet2_000104 On1c(nc2ncccc12)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E17 compound treatment 0.474 0.227 12.19 12.1851 1.0 1911216 Bionet2_000105 Cc1ccc(SCC(=O)c2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E18 compound treatment 0.284 0.0367 1.97 1.9749 1.0 1911217 Bionet2_000106 O/C=C(\C#N)/c1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E19 compound treatment 0.414 0.167 8.96 8.9608 1.0 1911218 Bionet2_000107 Cc1ccccc1CSc2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E20 compound treatment 0.469 0.222 11.92 11.9164 1.0 1652251 Bionet2_000108 O=C(Nc1ccccc1)c2csc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E21 compound treatment 0.257 0.00975 0.52 0.5239 1.0 1911219 Bionet2_000109 Clc1ccc(cc1)S(=O)(=O)C2=CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E22 compound treatment 0.295 0.0478 2.57 2.566 1.0 1911220 Bionet2_000110 Nc1[nH]cc(c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E23 mock treatment 0.25 0.00275 0.15 0.1478 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 E24 mock treatment 0.255 0.00775 0.42 0.4165 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F01 compound treatment 0.239 -0.00825 -0.44 -0.4433 -1.0 1911221 Bionet2_000111 C/N=C(/Nc1ccc(Cl)cc1)\c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F02 compound treatment 0.251 0.00375 0.2 0.2015 1.0 1911222 Bionet2_000112 CC1SCC(=O)N(C1=O)c2ccc(cc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F03 compound treatment 0.341 0.0938 5.04 5.0379 1.0 1911223 Bionet2_000113 FC(F)(F)c1cnc(N2CCN(CCOCc3ccc(Cl)cc3)CC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F04 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1911224 Bionet2_000114 Cc1cc(C)n(n1)c2ncc(C#N)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F05 compound treatment 0.286 0.0388 2.08 2.0823 1.0 1911225 Bionet2_000115 N#CCc1nn2c(ccnc2c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F06 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1196043 Bionet2_000116 CC(C)(C#N)N1CCN(CC1)c2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F07 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1911226 Bionet2_000117 Clc1cccc(n1)C(C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F08 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1468964 Bionet2_000118 OC(=O)CSCC(=O)Nc1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F09 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1911227 Bionet2_000119 Cc1cc(C)cc(c1)C(=N)Nc2cccc(C#N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F10 compound treatment 0.274 0.0267 1.44 1.4375 1.0 1344987 Bionet2_000120 COc1ccc(cc1)c2nnnn2c3ccc(F)cc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F11 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1911228 Bionet2_000121 CC(=O)Nc1ccccc1N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F12 compound treatment 0.254 0.00675 0.36 0.3627 1.0 1911229 Bionet2_000122 CS(=O)(=O)CC(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F13 compound treatment 0.373 0.126 6.76 6.7575 1.0 1911230 Bionet2_000123 Clc1snnc1c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F14 compound treatment 0.265 0.0177 0.95 0.9538 1.0 1911231 Bionet2_000124 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ncn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F15 compound treatment 0.436 0.189 10.14 10.143 1.0 1911232 Bionet2_000125 Cc1sc(nc1O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F16 compound treatment 0.503 0.256 13.74 13.7435 1.0 1616837 Bionet2_000126 Cc1ccc(Cc2ccc(NN)nn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F17 compound treatment 0.297 0.0498 2.67 2.6735 1.0 1698559 Bionet2_000127 Clc1ccc(CN2C(=O)CSCC2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F18 compound treatment 0.258 0.0107 0.58 0.5777 1.0 1911233 Bionet2_000128 Fc1ccc(cc1)C2CC(=O)CC(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F19 compound treatment 0.266 0.0187 1.01 1.0076 1.0 1911234 Bionet2_000129 CCOC(=O)c1cnc2ccc(cc2c1O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F20 compound treatment 0.263 0.0158 0.85 0.8464 1.0 1911235 Bionet2_000130 FC(F)(F)c1cnc(SCC#N)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F21 compound treatment 0.246 -0.00125 -0.07 -0.0672 -1.0 1911236 Bionet2_000131 FC(F)(F)c1cnc(Sc2nc[nH]n2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F22 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911237 Bionet2_000132 O=C(CC(C#N)C#N)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F23 mock treatment 0.246 -0.00125 -0.07 -0.0672 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 F24 mock treatment 0.24 -0.00725 -0.39 -0.3896 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G01 compound treatment 0.489 0.242 12.99 12.9911 1.0 1638340 Bionet2_000133 CC(C)(C)NC(=O)n1ccc(n1)c2ccc(cc2)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G02 compound treatment 0.251 0.00375 0.2 0.2015 1.0 1084210 Bionet2_000134 N(c1ncn[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G03 compound treatment 0.26 0.0127 0.69 0.6852 1.0 1911238 Bionet2_000135 Cn1nc(Cl)c(Cl)c1Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G04 compound treatment 0.254 0.00675 0.36 0.3627 1.0 1911239 Bionet2_000136 CN(C)/C=C/1\OC(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G05 compound treatment 0.365 0.118 6.33 6.3276 1.0 1911240 Bionet2_000137 O/N=C\C(/C=C/c1ccccc1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G06 compound treatment 0.261 0.0138 0.74 0.7389 1.0 1911241 Bionet2_000138 FC(F)(F)c1cc(Nc2ccccc2)nc(n1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G07 compound treatment 0.257 0.00975 0.52 0.5239 1.0 1308091 Bionet2_000139 CN(C)c1nc(N)ncc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G08 compound treatment 0.264 0.0168 0.9 0.9001 1.0 1911242 Bionet2_000140 Oc1ccc2c(cc(nc2n1)C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G09 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1911243 Bionet2_000141 COc1ccc(cc1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G10 compound treatment 0.276 0.0288 1.54 1.545 1.0 1555662 Bionet2_000142 Cc1nc(N)oc1C(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G11 compound treatment 0.29 0.0428 2.3 2.2973 1.0 1911244 Bionet2_000143 FC(F)(F)c1cccc(c1)S(=O)(=O)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G12 compound treatment 0.325 0.0778 4.18 4.1781 1.0 1911245 Bionet2_000144 Clc1ccc(CNC2=Nc3ccccc3CS2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G13 compound treatment 0.281 0.0338 1.81 1.8137 1.0 1911246 Bionet2_000145 CC(Oc1ccccc1)c2ccnc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G14 compound treatment 0.249 0.00175 0.09 0.094 1.0 1911247 Bionet2_000146 COc1ccc(/C=[N+](/C)\[O-])cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G15 compound treatment 0.299 0.0517 2.78 2.7809 1.0 1911248 Bionet2_000147 N#Cc1cnn2c(ccnc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G16 compound treatment 0.291 0.0437 2.35 2.351 1.0 1911249 Bionet2_000148 O/N=C/c1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G17 compound treatment 0.431 0.184 9.87 9.8743 1.0 1911250 Bionet2_000149 Cc1ccc(Sc2cnc(N)nc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G18 compound treatment 0.282 0.0348 1.87 1.8674 1.0 1911251 Bionet2_000150 CC(Oc1ccc(Cl)cc1)/C(=N/O)/C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G19 compound treatment 0.291 0.0437 2.35 2.351 1.0 1297322 Bionet2_000151 CCNC(=O)n1nccc1C(C)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G20 compound treatment 0.309 0.0617 3.32 3.3183 1.0 1911252 Bionet2_000152 CNC(=O)c1csc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G21 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1146228 Bionet2_000153 O=C(CC(=O)N1CCc2ccccc12)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G22 compound treatment 0.3 0.0527 2.83 2.8347 1.0 1911253 Bionet2_000154 FC(F)(F)c1cccc(NC(=O)c2csc(n2)c3ccncc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G23 mock treatment 0.256 0.00875 0.47 0.4702 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 G24 mock treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H01 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1911254 Bionet2_000155 CC(C)/N=C(/Nc1ccc(Cl)cc1)\c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H02 compound treatment 0.254 0.00675 0.36 0.3627 1.0 1911255 Bionet2_000156 CC1SCC(=O)N(C1=O)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H03 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911256 Bionet2_000157 FC(F)(F)c1cnc(C2C(=O)Nc3ccccc23)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H04 compound treatment 0.335 0.0877 4.72 4.7155 1.0 1911257 Bionet2_000158 N#CCOc1ncn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H05 compound treatment 0.257 0.00975 0.52 0.5239 1.0 1342520 Bionet2_000159 N#Cc1c(cccc1n2ccnc2)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H06 compound treatment 0.344 0.0968 5.2 5.1991 1.0 1911258 Bionet2_000160 COC(=O)C1=Cc2cc(OC)ccc2OC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H07 compound treatment 0.236 -0.0113 -0.6 -0.6046 -1.0 1911259 Bionet2_000161 CN(C)/C=C/c1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H08 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1911260 Bionet2_000162 Cc1nc(c(s1)C(=O)N)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H09 compound treatment 0.242 -0.00525 -0.28 -0.2821 -1.0 1596372 Bionet2_000163 CC(C)C(=O)Nc1ccc(cc1)N2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H10 compound treatment 0.281 0.0338 1.81 1.8137 1.0 1911261 Bionet2_000164 OC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H11 compound treatment 0.452 0.205 11.0 11.0028 1.0 1452532 Bionet2_000165 NC(=O)COc1ncn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H12 compound treatment 0.239 -0.00825 -0.44 -0.4433 -1.0 1434477 Bionet2_000166 COc1ccc(cc1)N2C(=O)CSC(C2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H13 compound treatment 0.301 0.0537 2.89 2.8884 1.0 1911262 Bionet2_000167 CCOC(=O)c1nc(C)n(n1)c2cc(Cl)cc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H14 compound treatment 0.264 0.0168 0.9 0.9001 1.0 1911263 Bionet2_000168 OC(=O)CSc1cccc[n+]1[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H15 compound treatment 0.296 0.0488 2.62 2.6197 1.0 1911264 Bionet2_000169 CN(O)/C=C/C(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H16 compound treatment 0.416 0.169 9.07 9.0683 1.0 1911265 Bionet2_000170 Clc1ccc(Cc2ccc(Cl)nn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H17 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1356653 Bionet2_000171 Clc1ccc(CN2C(=O)CS(=O)(=O)CC2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H18 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1911266 Bionet2_000172 Fc1cccc(Cl)c1C2CC(=O)CC(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H19 compound treatment 0.394 0.147 7.89 7.886 1.0 1005228 Bionet2_000173 CCOC(=O)c1cnc2ccccc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H20 compound treatment 0.388 0.141 7.56 7.5636 1.0 1602526 Bionet2_000174 COc1ccc(cc1)c2ccc(C#N)c(Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H21 compound treatment 0.365 0.118 6.33 6.3276 1.0 1911267 Bionet2_000175 Cn1cc(cc1/C=N\O)C(=O)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H22 compound treatment 0.26 0.0127 0.69 0.6852 1.0 1018215 Bionet2_000176 Nc1[nH]nc(CC#N)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H23 mock treatment 0.251 0.00375 0.2 0.2015 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 H24 mock treatment 0.25 0.00275 0.15 0.1478 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I01 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1911268 Bionet2_000177 O/N=C/NC(=O)c1ccccc1n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I02 compound treatment 0.298 0.0508 2.73 2.7272 1.0 1911269 Bionet2_000178 Clc1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I03 compound treatment 0.269 0.0217 1.17 1.1688 1.0 1009271 Bionet2_000179 N#CN(Cc1ccccc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I04 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911270 Bionet2_000180 O=C1O/C(=C\Nc2ccccc2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I05 compound treatment 0.257 0.00975 0.52 0.5239 1.0 1911271 Bionet2_000181 CC(C)(C)c1cc[nH]n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I06 compound treatment 0.253 0.00575 0.31 0.309 1.0 1911272 Bionet2_000182 Cn1nc(cc1O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I07 compound treatment 0.253 0.00575 0.31 0.309 1.0 1155652 Bionet2_000183 CN(C)c1nn(cc1c2ccccc2)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I08 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911273 Bionet2_000184 OC(=O)c1c[nH]c(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I09 compound treatment 0.411 0.164 8.8 8.7996 1.0 1911274 Bionet2_000185 Cc1snc(SCc2c(F)cccc2Cl)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I10 compound treatment 0.28 0.0328 1.76 1.7599 1.0 1425076 Bionet2_000186 Cc1ccc(cc1)C(=O)Oc2cccnc2I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I11 compound treatment 0.537 0.29 15.57 15.5706 1.0 1911275 Bionet2_000187 COc1ccc(Sc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I12 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911276 Bionet2_000188 C(NC1=Nc2ccccc2CS1)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I13 compound treatment 0.35 0.103 5.52 5.5216 1.0 1503995 Bionet2_000189 CC(Oc1ccc(Cl)cc1Cl)c2ccnc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I14 compound treatment 0.303 0.0558 3.0 2.9959 1.0 1911277 Bionet2_000190 Cn1nc(c(C#N)c1NCc2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I15 compound treatment 0.308 0.0607 3.26 3.2646 1.0 1585357 Bionet2_000191 COc1ccc(cc1)c2ccnc3c(C#N)cnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I16 compound treatment 0.29 0.0428 2.3 2.2973 1.0 1911278 Bionet2_000192 CCOC(=O)CNc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I17 compound treatment 0.491 0.244 13.1 13.0986 1.0 1911279 Bionet2_000193 Cc1n[nH]cc1Sc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I18 compound treatment 0.253 0.00575 0.31 0.309 1.0 1024030 Bionet2_000194 OCCNC(=O)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I19 compound treatment 0.265 0.0177 0.95 0.9538 1.0 1911280 Bionet2_000195 CC(Oc1cccc(c1)C(F)(F)F)c2ccnc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I20 compound treatment 0.272 0.0248 1.33 1.33 1.0 1911281 Bionet2_000196 CNC(=O)c1sc(nc1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I21 compound treatment 0.297 0.0498 2.67 2.6735 1.0 1911282 Bionet2_000197 NC(=C(C#N)C#N)SCc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I22 compound treatment 0.456 0.209 11.22 11.2178 1.0 1911283 Bionet2_000198 FC(F)(F)c1ccc(NC(=O)c2csc(n2)c3ccncc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I23 mock treatment 0.253 0.00575 0.31 0.309 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 I24 mock treatment 0.261 0.0138 0.74 0.7389 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J01 compound treatment 0.24 -0.00725 -0.39 -0.3896 -1.0 1911284 Bionet2_000199 CCC/N=C(/Nc1ccc(Cl)cc1)\c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J02 compound treatment 0.249 0.00175 0.09 0.094 1.0 1911285 Bionet2_000200 C/[N+](=C\C1C(=O)CCCC1=O)/[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J03 compound treatment 0.549 0.302 16.22 16.2154 1.0 1911286 Bionet2_000201 CCCSc1ccc(cn1)C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J04 compound treatment 0.243 -0.00425 -0.23 -0.2284 -1.0 1049975 Bionet2_000202 CC(C)(C#N)N1CCN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J05 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1911287 Bionet2_000203 CN(C)c1nc(N(C)C)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J06 compound treatment 0.432 0.185 9.93 9.9281 1.0 1911288 Bionet2_000204 COc1cccc2C=C(COc12)C(=O)n3cccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J07 compound treatment 0.295 0.0478 2.57 2.566 1.0 1911289 Bionet2_000205 OC(=O)C1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J08 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1911290 Bionet2_000206 Cc1nc(c(s1)c2nc[nH]n2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J09 compound treatment 0.232 -0.0153 -0.82 -0.8195 -1.0 1911291 Bionet2_000207 Oc1cccc(Oc2ncc(cc2Cl)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J10 compound treatment 0.299 0.0517 2.78 2.7809 1.0 1911292 Bionet2_000208 CC(=O)OC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J11 compound treatment 0.253 0.00575 0.31 0.309 1.0 1911293 Bionet2_000209 ClCCCC(=O)Nc1ccccc1N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J12 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1607522 Bionet2_000210 O=C1CSC(C(=O)N1c2ccc(C#N)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J13 compound treatment 0.355 0.108 5.79 5.7903 1.0 1911294 Bionet2_000211 C(Sc1snnc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J14 compound treatment 0.504 0.257 13.8 13.7972 1.0 1092346 Bionet2_000212 NNc1cccc(Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J15 compound treatment 0.243 -0.00425 -0.23 -0.2284 -1.0 1911295 Bionet2_000213 C/[N+](=C\C1C(=O)CC(C)(C)CC1=O)/[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J16 compound treatment 0.281 0.0338 1.81 1.8137 1.0 1911296 Bionet2_000214 NC(=O)c1ccc(Oc2ncc(cc2Cl)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J17 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1679118 Bionet2_000215 CCOC(=O)CC1N(CCNC1=O)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J18 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1118739 Bionet2_000216 OC1=C(C2NCCc3ccccc23)C(=O)CC(C1)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J19 compound treatment 0.298 0.0508 2.73 2.7272 1.0 1058014 Bionet2_000217 CCOC(=O)c1cnc2ccccc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J20 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1125303 Bionet2_000218 CNCC(O)(c1ccc(Cl)cc1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J21 compound treatment 0.285 0.0377 2.03 2.0286 1.0 1911297 Bionet2_000219 CCOC(=O)C=C1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J22 compound treatment 0.248 7.5E-4 0.04 0.0403 1.0 1164147 Bionet2_000220 Cc1nn(C)c(O)c1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J23 mock treatment 0.242 -0.00525 -0.28 -0.2821 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 J24 mock treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K01 compound treatment 0.325 0.0778 4.18 4.1781 1.0 1911298 Bionet2_000221 COC(=O)c1ccc(cc1)n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K02 compound treatment 0.294 0.0468 2.51 2.5122 1.0 1537467 Bionet2_000222 CCOC(=O)c1c(C)nc2c(C)cccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K03 compound treatment 0.312 0.0648 3.48 3.4795 1.0 1911299 Bionet2_000223 Clc1ccccc1CN(Cc2ccccc2Cl)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K04 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1911300 Bionet2_000224 FC(F)(F)Oc1ccc(N/C=C/2\OC(=O)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K05 compound treatment 0.38 0.133 7.13 7.1337 1.0 1911301 Bionet2_000225 Cc1ccc(N/C=C(/C#N)\c2ccsc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K06 compound treatment 0.264 0.0168 0.9 0.9001 1.0 1531937 Bionet2_000226 OCC1(CO)CCc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K07 compound treatment 0.407 0.16 8.58 8.5846 1.0 1137410 Bionet2_000227 CNc1c2CCCCc2nn1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K08 compound treatment 0.263 0.0158 0.85 0.8464 1.0 1460414 Bionet2_000228 CN(C)C(=O)c1cnc(Cl)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K09 compound treatment 0.42 0.173 9.28 9.2832 1.0 1571171 Bionet2_000229 CN(C)c1sc(cc1c2ccccc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K10 compound treatment 0.264 0.0168 0.9 0.9001 1.0 1638969 Bionet2_000230 NC(=O)C1CCN(CC1)c2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K11 compound treatment 0.287 0.0398 2.14 2.1361 1.0 1911302 Bionet2_000231 COc1ccc(Oc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K12 compound treatment 0.544 0.297 15.95 15.9467 1.0 1669821 Bionet2_000232 COc1cccc(NC(=O)c2ccc(nc2)n3cccn3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K13 compound treatment 0.297 0.0498 2.67 2.6735 1.0 1911303 Bionet2_000233 Cc1nn(C)c(C)c1Cc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K14 compound treatment 0.373 0.126 6.76 6.7575 1.0 1709434 Bionet2_000234 CCOC(=O)CNc1ccccc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K15 compound treatment 0.374 0.127 6.81 6.8113 1.0 1447339 Bionet2_000235 Nc1c(cnc2c(C#N)cnn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K16 compound treatment 0.268 0.0208 1.12 1.1151 1.0 1911304 Bionet2_000236 NC(=O)CNc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K17 compound treatment 0.377 0.13 6.97 6.9725 1.0 1911305 Bionet2_000237 Cc1ccc2occ(/C=N/O)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K18 compound treatment 0.375 0.128 6.87 6.865 1.0 1911306 Bionet2_000238 Cc1cc(C)n(CCOc2ncc(cc2Cl)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K19 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1911307 Bionet2_000239 CC(Oc1ccccc1)c2ccn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K20 compound treatment 0.481 0.234 12.56 12.5612 1.0 1911308 Bionet2_000240 Clc1cccc(OCc2ncn(n2)c3cccc(Cl)n3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K21 compound treatment 0.434 0.187 10.04 10.0356 1.0 1911309 Bionet2_000241 O=C1OCC(=C1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K22 compound treatment 0.318 0.0707 3.8 3.802 1.0 1335081 Bionet2_000242 CCOC(=O)c1cc([nH]c1N2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K23 mock treatment 0.255 0.00775 0.42 0.4165 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 K24 mock treatment 0.25 0.00275 0.15 0.1478 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L01 compound treatment 0.24 -0.00725 -0.39 -0.3896 -1.0 1911310 Bionet2_000243 CC/N=C(/Nc1ccc(Cl)cc1)\c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L02 compound treatment 0.292 0.0447 2.4 2.4048 1.0 1911311 Bionet2_000244 OC(=O)CC(=O)Nc1ccc(OC(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L03 compound treatment 0.368 0.121 6.49 6.4889 1.0 1506643 Bionet2_000245 CCCS(=O)(=O)c1ccc(cn1)C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L04 compound treatment 0.408 0.161 8.64 8.6384 1.0 1495251 Bionet2_000246 COc1cccc2C=C(COc12)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L05 compound treatment 0.253 0.00575 0.31 0.309 1.0 1911312 Bionet2_000247 NC(=O)C(c1ccccc1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L06 compound treatment 0.423 0.176 9.44 9.4444 1.0 1911313 Bionet2_000248 COc1ccc2OCC(=Cc2c1)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L07 compound treatment 0.238 -0.00925 -0.5 -0.4971 -1.0 1064931 Bionet2_000249 NOCc1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L08 compound treatment 0.275 0.0278 1.49 1.4912 1.0 1911314 Bionet2_000250 Clc1ccc(Oc2cnns2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L09 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1212257 Bionet2_000251 Nc1ccc(Sc2ccccc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L10 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911315 Bionet2_000252 COC(=O)C(/N=C/c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L11 compound treatment 0.246 -0.00125 -0.07 -0.0672 -1.0 1911316 Bionet2_000253 FC(F)(F)c1cccc(c1)C(C#N)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L12 compound treatment 0.249 0.00175 0.09 0.094 1.0 1911317 Bionet2_000254 COc1cc(/C=[N+](/C)\[O-])ccc1OCc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L13 compound treatment 0.468 0.221 11.86 11.8626 1.0 1911318 Bionet2_000255 Clc1ccc(cc1)c2nnsc2SCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L14 compound treatment 0.425 0.178 9.55 9.5519 1.0 1911319 Bionet2_000256 Cc1[nH]c2ccccc2c1c3ccc(Cl)nn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L15 compound treatment 0.25 0.00275 0.15 0.1478 1.0 1911320 Bionet2_000257 O=C1CSCC(=O)N1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L16 compound treatment 0.322 0.0747 4.02 4.0169 1.0 1703307 Bionet2_000258 NC(=O)c1cc(c[nH]1)C(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L17 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1911321 Bionet2_000259 CCOC(=O)c1sc(C)nc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L18 compound treatment 0.306 0.0587 3.16 3.1571 1.0 1911322 Bionet2_000260 Clc1ccc(cc1)c2ccc(C#N)c(Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L19 compound treatment 0.238 -0.00925 -0.5 -0.4971 -1.0 1222934 Bionet2_000261 CCOC(=O)c1cnc2cc(Cl)cc(Cl)c2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L20 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1911323 Bionet2_000262 Nc1c(Cl)cc(c[n+]1[O-])C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L21 compound treatment 0.27 0.0227 1.22 1.2225 1.0 1443080 Bionet2_000263 Clc1ccc(cc1Cl)N2C(=O)CS(=O)(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L22 compound treatment 0.31 0.0628 3.37 3.3721 1.0 1911324 Bionet2_000264 COc1cnc(nc1O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L23 mock treatment 0.241 -0.00625 -0.34 -0.3359 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 L24 mock treatment 0.249 0.00175 0.09 0.094 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M01 compound treatment 0.405 0.158 8.48 8.4772 1.0 1685922 Bionet2_000265 O=C(CC1OC(=O)c2ccccc12)c3ccc(cc3)n4ccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M02 compound treatment 0.266 0.0187 1.01 1.0076 1.0 1565484 Bionet2_000266 Cc1nc2cc(C)ccn2c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M03 compound treatment 0.291 0.0437 2.35 2.351 1.0 1911325 Bionet2_000267 COc1cc(Br)cc(/C=N\c2ccccc2)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M04 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1911326 Bionet2_000268 Oc1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M05 compound treatment 0.294 0.0468 2.51 2.5122 1.0 1911327 Bionet2_000269 CSc1cccc(N/C=C(/C#N)\c2ccsc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M06 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1911328 Bionet2_000270 CN(C)CCCNc1nnc(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M07 compound treatment 0.278 0.0308 1.65 1.6524 1.0 1911329 Bionet2_000271 Clc1ccc(N/C=C(\C#N)/c2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M08 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1622885 Bionet2_000272 COC(=O)c1cn(c2ccccc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M09 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911330 Bionet2_000273 CS/C(=N/C=[N+](C)C)/Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M10 compound treatment 0.303 0.0558 3.0 2.9959 1.0 1441352 Bionet2_000274 CC1=C(CC(=O)c2ccccc2)C(=O)c3ccccc3C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M11 compound treatment 0.307 0.0597 3.21 3.2108 1.0 1483376 Bionet2_000275 Cc1ccc(Oc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M12 compound treatment 0.485 0.238 12.78 12.7762 1.0 1396774 Bionet2_000276 COc1ccccc1NC(=O)c2ccc(nc2)n3cccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M13 compound treatment 0.382 0.135 7.24 7.2412 1.0 1911331 Bionet2_000277 FC(F)(F)c1ccc(cc1)N2CSCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M14 compound treatment 0.358 0.111 5.95 5.9515 1.0 1192842 Bionet2_000278 CCOC(=O)c1[nH]c2ccccc2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M15 compound treatment 0.306 0.0587 3.16 3.1571 1.0 1911332 Bionet2_000279 Clc1ccc(c(Cl)c1)c2ccnc3c(C#N)cnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M16 compound treatment 0.428 0.181 9.71 9.7131 1.0 1911333 Bionet2_000280 Cc1ccc(/C=C/C(=O)Cc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M17 compound treatment 0.508 0.261 14.01 14.0122 1.0 1911334 Bionet2_000281 Fc1ccc(/C=C/c2onc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M18 compound treatment 0.273 0.0257 1.38 1.3838 1.0 1911335 Bionet2_000282 FC(F)(F)c1cc(n2nc(CC#N)c(C#N)c2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M19 compound treatment 0.276 0.0288 1.54 1.545 1.0 1134757 Bionet2_000283 CC(Oc1ccccc1)c2ccnn2C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M20 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911336 Bionet2_000284 CC(c1cc[nH]n1)n2cncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M21 compound treatment 0.266 0.0187 1.01 1.0076 1.0 1911337 Bionet2_000285 O=c1ccn(cc1)c2ccc(cc2)c3ccn[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M22 compound treatment 0.29 0.0428 2.3 2.2973 1.0 1616173 Bionet2_000286 CCOC(=O)c1c(N)[nH]cc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M23 mock treatment 0.243 -0.00425 -0.23 -0.2284 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 M24 mock treatment 0.252 0.00475 0.26 0.2553 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N01 compound treatment 0.242 -0.00525 -0.28 -0.2821 -1.0 1911338 Bionet2_000287 C/N=C(/Nc1cccc(c1)C(F)(F)F)\c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N02 compound treatment 0.259 0.0118 0.63 0.6314 1.0 1911339 Bionet2_000288 OC(=O)CC(=O)Oc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N03 compound treatment 0.476 0.229 12.29 12.2925 1.0 1911340 Bionet2_000289 CC(=O)Nc1ccc(Sc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N04 compound treatment 0.295 0.0478 2.57 2.566 1.0 1164832 Bionet2_000290 COc1ccc2OCC(=Cc2c1)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N05 compound treatment 0.289 0.0418 2.24 2.2436 1.0 1911341 Bionet2_000291 FC(F)(F)c1cnc(C(C#N)c2ccc(Cl)cc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N06 compound treatment 0.267 0.0198 1.06 1.0613 1.0 1318337 Bionet2_000292 COC(=O)c1sccc1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N07 compound treatment 0.231 -0.0163 -0.87 -0.8732 -1.0 1911342 Bionet2_000293 NOCc1ccccc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N08 compound treatment 0.269 0.0217 1.17 1.1688 1.0 1911343 Bionet2_000294 Cc1cc(C)nc(OC(=O)c2ccc(Cl)cc2Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N09 compound treatment 0.378 0.131 7.03 7.0262 1.0 1911344 Bionet2_000295 Clc1ccc(cc1)c2nn[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N10 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1911345 Bionet2_000296 Fc1ccc(SCC(=O)NCC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N11 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1778227 Bionet2_000297 N#CC(/C=C/c1ccccc1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N12 compound treatment 0.238 -0.00925 -0.5 -0.4971 -1.0 1911346 Bionet2_000298 COc1cccc(/C=[N+](/C)\[O-])c1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N13 compound treatment 0.305 0.0578 3.1 3.1034 1.0 1911347 Bionet2_000299 Clc1ccc(cc1)C(C#N)C(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N14 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1911348 Bionet2_000300 Oc1ccc(Cc2ccccc2Br)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N15 compound treatment 0.239 -0.00825 -0.44 -0.4433 -1.0 1911349 Bionet2_000301 Cc1ccccc1N2C(=O)CSCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N16 compound treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1911350 Bionet2_000302 Nc1ccccc1Sc2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N17 compound treatment 0.284 0.0367 1.97 1.9749 1.0 1911351 Bionet2_000303 CN(C)/C=C/c1nc(c(C#N)s1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N18 compound treatment 0.307 0.0597 3.21 3.2108 1.0 1911352 Bionet2_000304 FC(F)(F)c1cccc(c1)c2ccc(C#N)c(Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N19 compound treatment 0.252 0.00475 0.26 0.2553 1.0 1617155 Bionet2_000305 Oc1ccc(O)c(c1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N20 compound treatment 0.224 -0.0233 -1.25 -1.2494 -1.0 1082244 Bionet2_000306 N#CC(N1CCOCC1)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N21 compound treatment 0.236 -0.0113 -0.6 -0.6046 -1.0 1911353 Bionet2_000307 CC1SCC(=O)N(C1=O)c2ccc(F)cc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N22 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911354 Bionet2_000308 OC(=O)c1cnc(nc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N23 mock treatment 0.236 -0.0113 -0.6 -0.6046 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 N24 mock treatment 0.24 -0.00725 -0.39 -0.3896 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O01 compound treatment 0.298 0.0508 2.73 2.7272 1.0 1911355 Bionet2_000309 NC(=O)c1ccc(cc1)n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O02 compound treatment 0.262 0.0147 0.79 0.7926 1.0 1377035 Bionet2_000310 O=C(c1cnc(Nc2ccccc2)s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O03 compound treatment 0.279 0.0318 1.71 1.7062 1.0 1490357 Bionet2_000311 C(N(Cc1ccccc1)c2nnn[nH]2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O04 compound treatment 0.271 0.0238 1.28 1.2763 1.0 1911356 Bionet2_000312 FC(F)(F)c1cc(Sc2ccccc2)nc(n1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O05 compound treatment 0.354 0.107 5.74 5.7365 1.0 1911357 Bionet2_000313 O=C(CSc1ccccc1)CSc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O06 compound treatment 0.27 0.0227 1.22 1.2225 1.0 1911358 Bionet2_000314 CSc1nc2ccsc2c(=O)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O07 compound treatment 0.258 0.0107 0.58 0.5777 1.0 1069245 Bionet2_000315 CN(C)c1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O08 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1678531 Bionet2_000316 CNC(=O)c1cn(c2ccccc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O09 compound treatment 0.3 0.0527 2.83 2.8347 1.0 1911359 Bionet2_000317 CNC(=O)c1cc2c(=O)c3ccccc3oc2nc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O10 compound treatment 0.263 0.0158 0.85 0.8464 1.0 1449361 Bionet2_000318 Cc1nn(c(N)c1c2ccc(Cl)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O11 compound treatment 0.251 0.00375 0.2 0.2015 1.0 1227594 Bionet2_000319 CC(=O)Nc1ccc(Oc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O12 compound treatment 0.319 0.0717 3.86 3.8557 1.0 1214945 Bionet2_000320 Clc1ccc(CNC(=O)c2ccc(nc2)n3cccn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O13 compound treatment 0.268 0.0208 1.12 1.1151 1.0 1911360 Bionet2_000321 Cc1ccc(cc1)N2CSCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O14 compound treatment 0.358 0.111 5.95 5.9515 1.0 1911361 Bionet2_000322 Clc1ccc(NC(=O)OCc2cn(nn2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O15 compound treatment 0.365 0.118 6.33 6.3276 1.0 1507260 Bionet2_000323 CC(Oc1ccc(Cl)cc1)c2ccnc3c(C#N)cnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O16 compound treatment 0.279 0.0318 1.71 1.7062 1.0 1911362 Bionet2_000324 On1c(nc2ccc(Cl)cc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O17 compound treatment 0.516 0.269 14.44 14.4421 1.0 1911363 Bionet2_000325 COc1ccc(/C=C/c2onc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O18 compound treatment 0.26 0.0127 0.69 0.6852 1.0 1020435 Bionet2_000326 Cc1cc(C)n2nc(CC#N)c(C#N)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O19 compound treatment 0.253 0.00575 0.31 0.309 1.0 1911364 Bionet2_000327 O/N=C/c1c(Cl)nc2sccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O20 compound treatment 0.429 0.182 9.77 9.7669 1.0 1911365 Bionet2_000328 CCOC(=O)c1csc(n1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O21 compound treatment 0.255 0.00775 0.42 0.4165 1.0 1911366 Bionet2_000329 Clc1nc2sccn2c1/C=N/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O22 compound treatment 0.243 -0.00425 -0.23 -0.2284 -1.0 1177958 Bionet2_000330 NC(=O)c1cnn(c1)C2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O23 mock treatment 0.251 0.00375 0.2 0.2015 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 O24 mock treatment 0.256 0.00875 0.47 0.4702 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P01 compound treatment 0.273 0.0257 1.38 1.3838 1.0 1911367 Bionet2_000331 CCNc1nc(O)cc(n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P02 compound treatment 0.29 0.0428 2.3 2.2973 1.0 1911368 Bionet2_000332 CN(C)/C=C/S(=O)(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P03 compound treatment 0.331 0.0838 4.5 4.5005 1.0 1911369 Bionet2_000333 CC(C)C(=O)Nc1ccc(Sc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P04 compound treatment 0.438 0.191 10.25 10.2505 1.0 1911370 Bionet2_000334 Clc1ccc(NC(=O)C2=Cc3ccccc3OC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P05 compound treatment 0.247 -2.5E-4 -0.01 -0.0134 -1.0 1911371 Bionet2_000335 ONC(=O)Cc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P06 compound treatment 0.359 0.112 6.01 6.0052 1.0 1911372 Bionet2_000336 COC(=O)c1sccc1OCc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P07 compound treatment 0.299 0.0517 2.78 2.7809 1.0 1911373 Bionet2_000337 COC(=O)C1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P08 compound treatment 0.4 0.153 8.21 8.2085 1.0 1911374 Bionet2_000338 O=C1O/C(=C\C=C\c2ccccc2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P09 compound treatment 0.249 0.00175 0.09 0.094 1.0 1911375 Bionet2_000339 Cn1nc(c(C#N)c1N2CCN(CC2)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P10 compound treatment 0.425 0.178 9.55 9.5519 1.0 1911376 Bionet2_000340 CC(C)N(C(C)C)C(=O)CSc1ccc(Cl)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P11 compound treatment 0.225 -0.0222 -1.2 -1.1957 -1.0 1911377 Bionet2_000341 [O-][n+]1ccccc1SCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P12 compound treatment 0.294 0.0468 2.51 2.5122 1.0 1911378 Bionet2_000342 FC(F)(F)c1cnc(NCCN2C(=O)C=CC2=O)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P13 compound treatment 0.229 -0.0182 -0.98 -0.9807 -1.0 1581579 Bionet2_000343 Nc1c(cnn1C2CCS(=O)(=O)C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P14 compound treatment 0.281 0.0338 1.81 1.8137 1.0 1911379 Bionet2_000344 Cc1ccc(cc1)C(C#N)c2ccc(Cl)nn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P15 compound treatment 0.233 -0.0143 -0.77 -0.7658 -1.0 1911380 Bionet2_000345 FC(F)(F)c1cc(Cl)ccc1N2C(=O)CSCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P16 compound treatment 0.256 0.00875 0.47 0.4702 1.0 1911381 Bionet2_000346 CN(C)c1nnc2c(Cl)cc(cn12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P17 compound treatment 0.235 -0.0123 -0.66 -0.6583 -1.0 1110547 Bionet2_000347 CC(=O)Oc1cc(C)c(OC(=O)C)c(C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P18 compound treatment 0.277 0.0297 1.6 1.5987 1.0 1135495 Bionet2_000348 COc1ccc(cc1)c2ccc(C#N)c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P19 compound treatment 0.228 -0.0193 -1.03 -1.0345 -1.0 1911382 Bionet2_000349 CC(C(=O)N)n1cncn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P20 compound treatment 0.231 -0.0163 -0.87 -0.8732 -1.0 1399627 Bionet2_000350 OC(=O)c1cn(c2ccc(F)cc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P21 compound treatment 0.237 -0.0103 -0.55 -0.5508 -1.0 1911383 Bionet2_000351 CC1SCC(=O)N(C1=O)c2cc(Cl)ccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P22 compound treatment 0.242 -0.00525 -0.28 -0.2821 -1.0 1911384 Bionet2_000352 Cn1nc(c(C(=O)Nc2ccc(F)cc2F)c1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P23 mock treatment 0.244 -0.00325 -0.17 -0.1746 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1364 P24 mock treatment 0.238 -0.00925 -0.5 -0.4971 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A01 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911385 Bionet2_000353 CCCn1c(=O)sc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A02 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911386 Bionet2_000354 Clc1ncc(/C=N/Cc2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A03 compound treatment 0.364 0.119 6.38 6.378 1.0 1613660 Bionet2_000355 COc1ccc(cc1)C(=O)C2CC2c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A04 compound treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1008010 Bionet2_000356 COC(C(=O)O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A05 compound treatment 0.244 -0.00131 -0.07 -0.0705 -1.0 1600295 Bionet2_000357 OCC(NC(=O)c1ccc(Cl)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A06 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911387 Bionet2_000358 Cc1nn(C)c(Sc2ccc(Cl)cc2)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A07 compound treatment 0.269 0.0237 1.27 1.2729 1.0 1911388 Bionet2_000359 FC(F)(F)c1ccccc1/C=N/c2sccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A08 compound treatment 0.224 -0.0213 -1.15 -1.1453 -1.0 1401675 Bionet2_000360 O=S(=O)(NCc1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A09 compound treatment 0.312 0.0667 3.58 3.5836 1.0 1413504 Bionet2_000361 Cc1ccc(cc1)S(=O)c2snnc2c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A10 compound treatment 0.228 -0.0173 -0.93 -0.9303 -1.0 1911389 Bionet2_000362 CCC(C)COc1ccc(O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A11 compound treatment 0.385 0.14 7.51 7.5065 1.0 1911390 Bionet2_000363 Cc1ccc(cc1)C(=O)/C=C/C(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A12 compound treatment 0.289 0.0437 2.35 2.3477 1.0 1119342 Bionet2_000364 COc1ccc(Oc2ccc(C#N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A13 compound treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1911391 Bionet2_000365 CC(C)(C)OC(=O)N(Cc1ccccc1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A14 compound treatment 0.289 0.0437 2.35 2.3477 1.0 1270317 Bionet2_000366 NC(=O)COc1ccc2c(C#N)c3ccccn3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A15 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1410795 Bionet2_000367 Clc1ncc(CN2CCOCC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A16 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1713360 Bionet2_000368 COc1ccc(cc1)n2ccc(O)c(Cc3ccc(Cl)cc3)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A17 compound treatment 0.305 0.0597 3.21 3.2075 1.0 1911392 Bionet2_000369 O=C(OCc1cncs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A18 compound treatment 0.261 0.0157 0.84 0.843 1.0 1911393 Bionet2_000370 CNc1cc(Cl)nc(SC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A19 compound treatment 0.233 -0.0123 -0.66 -0.6616 -1.0 1911394 Bionet2_000371 CNC(=O)CSc1nc[nH]n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A20 compound treatment 0.304 0.0587 3.15 3.1537 1.0 1911395 Bionet2_000372 NC(=N)SCc1ccc(cc1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A21 compound treatment 0.237 -0.00831 -0.45 -0.4467 -1.0 1911396 Bionet2_000373 CSc1ncc(CO)n1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A22 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1911397 Bionet2_000374 OC(CN1CCN(CC(O)C(F)(F)F)CC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A23 mock treatment 0.238 -0.00731 -0.39 -0.393 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 A24 mock treatment 0.258 0.0127 0.68 0.6818 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B01 compound treatment 0.369 0.124 6.65 6.6467 1.0 1911398 Bionet2_000375 Clc1cnc(NC(=O)c2cccs2)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B02 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1911399 Bionet2_000376 CCOC(=O)C1CCN(CC(O)C(F)(F)F)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B03 compound treatment 0.264 0.0187 1.0 1.0042 1.0 1537559 Bionet2_000377 OCCNc1ccc(Cl)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B04 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911400 Bionet2_000378 FC(F)(F)c1cccc(c1)C(=O)Nn2cnnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B05 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1734345 Bionet2_000379 CC(C)(CO)N1Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B06 compound treatment 0.234 -0.0113 -0.61 -0.6079 -1.0 1911401 Bionet2_000380 COC(=O)Cn1cncn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B07 compound treatment 0.273 0.0277 1.49 1.4879 1.0 1911402 Bionet2_000381 O=C1/C(=C/c2cccs2)/CCSc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B08 compound treatment 0.28 0.0347 1.86 1.864 1.0 1911403 Bionet2_000382 OC(=O)CCCSc1nccn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B09 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1911404 Bionet2_000383 OC(CN1CCCCC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B10 compound treatment 0.246 6.88E-4 0.04 0.0369 1.0 1138449 Bionet2_000384 O=S1(=O)CCN(Cc2cccnc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B11 compound treatment 0.463 0.218 11.7 11.6981 1.0 1911405 Bionet2_000385 Oc1nccc(c1C#N)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B12 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1911406 Bionet2_000386 Cc1ccccc1NC(=O)Cn2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B13 compound treatment 0.261 0.0157 0.84 0.843 1.0 3002060 Bionet2_000387 CCOC(=O)[CH-]C(=O)C(F)(F)F.C1CN(CCN1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B14 compound treatment 0.25 0.00469 0.25 0.2519 1.0 1472872 Bionet2_000388 NC1=CC(=O)CC(C1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B15 compound treatment 0.295 0.0497 2.67 2.6701 1.0 1237116 Bionet2_000389 COC(=O)c1ccc(NC(=O)c2ccccc2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B16 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1370553 Bionet2_000390 Cc1oncc1C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B17 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1731104 Bionet2_000391 CC(C)(C)OC(=O)N1CCC(CC1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B18 compound treatment 0.26 0.0147 0.79 0.7893 1.0 1352693 Bionet2_000392 COC(=O)c1cc2C(=O)NCCCn2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B19 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1028259 Bionet2_000393 CS(=O)(=O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B20 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911408 Bionet2_000394 CCC(C)NC(=O)/C=C/c1cc2OCOc2cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B21 compound treatment 0.234 -0.0113 -0.61 -0.6079 -1.0 1911409 Bionet2_000395 COc1ccccc1NC(=O)C2CC=CCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B22 compound treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1911410 Bionet2_000396 CC(CC(=O)Nc1cccc(c1)C(F)(F)F)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B23 mock treatment 0.267 0.0217 1.17 1.1654 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 B24 mock treatment 0.237 -0.00831 -0.45 -0.4467 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C01 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911411 Bionet2_000397 C=CCn1c(=O)sc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C02 compound treatment 0.257 0.0117 0.63 0.6281 1.0 1236592 Bionet2_000398 COC(=O)C1CCN(CC1)C(=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C03 compound treatment 0.31 0.0647 3.48 3.4762 1.0 1911412 Bionet2_000399 COc1ccc(cc1)C2CC2/C(=N/O)/C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C04 compound treatment 0.279 0.0337 1.81 1.8103 1.0 1027292 Bionet2_000400 CCOc1ccc2cc(Br)ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C05 compound treatment 0.27 0.0247 1.33 1.3267 1.0 1386099 Bionet2_000401 CC(=O)Nc1sccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C06 compound treatment 0.265 0.0197 1.06 1.058 1.0 1911413 Bionet2_000402 Cn1nc(OC(=O)Nc2ccccc2)cc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C07 compound treatment 0.362 0.117 6.27 6.2705 1.0 1559778 Bionet2_000403 COc1ccc(Oc2cc(C)c3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C08 compound treatment 0.255 0.00969 0.52 0.5206 1.0 1911414 Bionet2_000404 OC(=O)/C=C\C(=O)c1ccc(O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C09 compound treatment 0.329 0.0837 4.5 4.4972 1.0 1723713 Bionet2_000405 OC(=O)c1sccc1NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C10 compound treatment 0.291 0.0457 2.46 2.4552 1.0 1278592 Bionet2_000406 Oc1ccc(OCc2ccccc2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C11 compound treatment 0.264 0.0187 1.0 1.0042 1.0 1911415 Bionet2_000407 O/N=C/c1cccn1c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C12 compound treatment 0.267 0.0217 1.17 1.1654 1.0 1721911 Bionet2_000408 Fc1ccc(Oc2ccc(C#N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C13 compound treatment 0.356 0.111 5.95 5.9481 1.0 1911416 Bionet2_000409 Clc1ccc(/C=C/S(=O)(=O)NCc2cccs2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C14 compound treatment 0.374 0.129 6.92 6.9154 1.0 1494858 Bionet2_000410 CCOC(=O)COc1ccc2c(C#N)c3ccccn3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C15 compound treatment 0.296 0.0507 2.72 2.7238 1.0 1718786 Bionet2_000411 CSc1nc(NCC=C)c2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C16 compound treatment 0.258 0.0127 0.68 0.6818 1.0 1911417 Bionet2_000412 O/N=C/c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C17 compound treatment 0.351 0.106 5.68 5.6794 1.0 1911418 Bionet2_000413 Cc1cccc(c1)C(=O)OCc2cncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C18 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1911419 Bionet2_000414 O/N=C\c1ccccc1Oc2ccc(Cl)c(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C19 compound treatment 0.26 0.0147 0.79 0.7893 1.0 1911420 Bionet2_000415 Fc1cccc(Cl)c1CSc2nc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C20 compound treatment 0.374 0.129 6.92 6.9154 1.0 1911421 Bionet2_000416 O/N=C/c1cc2OCOc2cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C21 compound treatment 0.28 0.0347 1.86 1.864 1.0 1539803 Bionet2_000417 CC(=O)Nc1ccccc1OCc2cnc(Cl)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C22 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1201233 Bionet2_000418 O=S1(=O)CCN(CC1)C2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C23 mock treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 C24 mock treatment 0.255 0.00969 0.52 0.5206 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D01 compound treatment 0.278 0.0327 1.76 1.7566 1.0 1014140 Bionet2_000419 OCc1cc2OCOc2cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D02 compound treatment 0.264 0.0187 1.0 1.0042 1.0 1348449 Bionet2_000420 CCC(C)NC(=O)c1ccc(cc1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D03 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1724435 Bionet2_000421 CC(C)CC(N1Cc2ccccc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D04 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1478566 Bionet2_000422 COc1ccc(cc1)C(=O)Nn2cnnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D05 compound treatment 0.358 0.113 6.06 6.0556 1.0 1109262 Bionet2_000423 CCOC(=O)c1cn2ccccc2c1C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D06 compound treatment 0.456 0.211 11.32 11.3219 1.0 1911422 Bionet2_000424 Clc1ncc(COC(=O)c2ccc(Cl)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D07 compound treatment 0.327 0.0817 4.39 4.3897 1.0 1911423 Bionet2_000425 Cn1nc(OCC(=O)N2CCOCC2)cc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D08 compound treatment 0.393 0.148 7.94 7.9364 1.0 1911424 Bionet2_000426 O/C=C/C(=O)c1cccc(OCc2ccc(Cl)cc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D09 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911425 Bionet2_000427 OC(CN1CCN(Cc2ccccc2)CC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D10 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1718077 Bionet2_000428 O=S1(=O)CCN(CCc2c[nH]c3ccccc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D11 compound treatment 0.528 0.283 15.19 15.191 1.0 1911426 Bionet2_000429 Oc1nccc(c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D12 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1911427 Bionet2_000430 FC(F)(F)c1nc2ccccc2n1CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D13 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911428 Bionet2_000431 CCc1ccc(NC(=O)/C=C/C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D14 compound treatment 0.321 0.0757 4.07 4.0673 1.0 1911429 Bionet2_000432 Clc1ccc2[nH]c(cc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D15 compound treatment 0.288 0.0427 2.29 2.2939 1.0 1911430 Bionet2_000433 CCOC(=O)c1c(C)nn(c1C)c2cccc(C)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D16 compound treatment 0.311 0.0657 3.53 3.5299 1.0 1911431 Bionet2_000434 COc1nc(nnc1C(F)(F)F)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D17 compound treatment 0.238 -0.00731 -0.39 -0.393 -1.0 1911432 Bionet2_000435 OC(=O)Cn1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D18 compound treatment 0.31 0.0647 3.48 3.4762 1.0 1303177 Bionet2_000436 CC(Oc1ccc(c(F)c1)c2ccccc2)c3ccnc(N)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D19 compound treatment 0.25 0.00469 0.25 0.2519 1.0 1911433 Bionet2_000437 OC(CNCCc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D20 compound treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1007595 Bionet2_000438 C(c1nnn[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D21 compound treatment 0.366 0.121 6.49 6.4855 1.0 1127187 Bionet2_000439 Fc1ccc(cc1)c2cn3cc(I)ccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D22 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1710802 Bionet2_000440 Cc1ccc(C)n1c2sccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D23 mock treatment 0.237 -0.00831 -0.45 -0.4467 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 D24 mock treatment 0.247 0.00169 0.09 0.0907 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E01 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1576946 Bionet2_000441 COCCn1c(=O)sc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E02 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911434 Bionet2_000442 Cc1ccc(Oc2ccccc2/C=C/C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E03 compound treatment 0.264 0.0187 1.0 1.0042 1.0 1911435 Bionet2_000443 Cc1cc(nc(O)c1S(=O)(=O)C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E04 compound treatment 0.255 0.00969 0.52 0.5206 1.0 1911436 Bionet2_000444 FC(F)(F)c1cnc(c(Cl)c1)n2nc(Br)nc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E05 compound treatment 0.257 0.0117 0.63 0.6281 1.0 1911437 Bionet2_000445 COC(=O)c1cc(Cl)sc1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E06 compound treatment 0.26 0.0147 0.79 0.7893 1.0 1569920 Bionet2_000446 OC(=O)c1cc(c2ccc(Cl)cc2)n(n1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E07 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1606273 Bionet2_000447 Cc1cc(nc2ccccc12)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E08 compound treatment 0.275 0.0297 1.6 1.5953 1.0 1294012 Bionet2_000448 COc1ccc(cc1)N2CCN(Cc3ccc(Cl)nc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E09 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911438 Bionet2_000449 COC(=O)c1sccc1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E10 compound treatment 0.271 0.0257 1.38 1.3804 1.0 1911439 Bionet2_000450 CSc1ccc(cc1)c2cccc(F)c2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E11 compound treatment 0.392 0.147 7.88 7.8827 1.0 1349965 Bionet2_000451 CCOC(=O)c1c2ccc(O)cc2n3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E12 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1131352 Bionet2_000452 Clc1ccc(Oc2ccc(C#N)cc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E13 compound treatment 0.261 0.0157 0.84 0.843 1.0 1142185 Bionet2_000453 COc1ccc(NS(=O)(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E14 compound treatment 0.302 0.0567 3.05 3.0463 1.0 1911440 Bionet2_000454 CN(C(=O)COc1cc(nn1C)C(F)(F)F)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E15 compound treatment 0.471 0.226 12.13 12.128 1.0 1539139 Bionet2_000455 O=C(Nc1ccc(oc1=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E16 compound treatment 0.276 0.0307 1.65 1.6491 1.0 1911441 Bionet2_000456 Brc1cnc(nc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E17 compound treatment 0.476 0.231 12.4 12.3967 1.0 1911442 Bionet2_000457 O=C(OCc1cncs1)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E18 compound treatment 0.596 0.351 18.85 18.8452 1.0 1168616 Bionet2_000458 Nc1ccc(cc1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E19 compound treatment 0.273 0.0277 1.49 1.4879 1.0 1911443 Bionet2_000459 Cc1cccc(CSc2nc[nH]n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E20 compound treatment 0.352 0.107 5.73 5.7332 1.0 1911444 Bionet2_000460 COc1cc(Br)cc(/C=N/O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E21 compound treatment 0.265 0.0197 1.06 1.058 1.0 1911445 Bionet2_000461 Brc1ccc(cc1)N2C(=O)C=CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E22 compound treatment 0.255 0.00969 0.52 0.5206 1.0 1417906 Bionet2_000462 Clc1ccc(CN2CCS(=O)(=O)CC2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E23 mock treatment 0.256 0.0107 0.57 0.5743 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 E24 mock treatment 0.247 0.00169 0.09 0.0907 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F01 compound treatment 0.377 0.132 7.08 7.0766 1.0 1608209 Bionet2_000463 COc1cccc2cc(oc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F02 compound treatment 0.527 0.282 15.14 15.1373 1.0 1606932 Bionet2_000464 CCC(C)NC(=O)c1cc(c[nH]1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F03 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911446 Bionet2_000465 OC(CNC1CCCC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F04 compound treatment 0.437 0.192 10.3 10.3009 1.0 1911447 Bionet2_000466 FC(F)(F)c1cccc(c1)C(=O)Nc2ccnc(n2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F05 compound treatment 0.365 0.12 6.43 6.4318 1.0 1599829 Bionet2_000467 CCOC(=O)c1c(cn2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F06 compound treatment 0.314 0.0687 3.69 3.6911 1.0 1911448 Bionet2_000468 Cc1ccccc1C(=O)OCc2cnc(Cl)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F07 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1572297 Bionet2_000469 OC(=O)C1CCC(=O)N1Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F08 compound treatment 0.388 0.143 7.67 7.6677 1.0 1911449 Bionet2_000470 OC(CSc1nc2ccccc2s1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F09 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1911450 Bionet2_000471 OC(CN1CCc2ccccc2C1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F10 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1474579 Bionet2_000472 CC(=O)NC(C1CCCCC1=O)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F11 compound treatment 0.359 0.114 6.11 6.1093 1.0 1523136 Bionet2_000473 O=S(=O)(c1ccccc1)n2ccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F12 compound treatment 0.244 -0.00131 -0.07 -0.0705 -1.0 1911451 Bionet2_000474 COc1ccccc1NC(=O)Cn2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F13 compound treatment 0.265 0.0197 1.06 1.058 1.0 1022215 Bionet2_000475 COC(=O)c1ccc(N)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F14 compound treatment 0.317 0.0717 3.85 3.8523 1.0 1911452 Bionet2_000476 CCOC(=O)c1cnn2c(C)c(Cc3cccc(F)c3)c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F15 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1667119 Bionet2_000477 Clc1cccc(c1)C2NCCc3nc[nH]c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F16 compound treatment 0.313 0.0677 3.64 3.6374 1.0 1911453 Bionet2_000478 Cc1cccc(OC(=O)Cn2c(nc3ccccc23)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F17 compound treatment 0.237 -0.00831 -0.45 -0.4467 -1.0 1911454 Bionet2_000479 CCn1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F18 compound treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1424688 Bionet2_000480 O=S1(=O)CCN(Cc2ccccn2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F19 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1686804 Bionet2_000481 CC(CO)N1CCS(=O)(=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F20 compound treatment 0.232 -0.0133 -0.72 -0.7154 -1.0 1047920 Bionet2_000482 C1Cc2[nH]cnc2C(N1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F21 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1539914 Bionet2_000483 Cc1ccc(CN2CCS(=O)(=O)CC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F22 compound treatment 0.268 0.0227 1.22 1.2192 1.0 1911455 Bionet2_000484 Cc1ccc(C)n1c2sccc2C(=O)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F23 mock treatment 0.235 -0.0103 -0.55 -0.5542 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 F24 mock treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G01 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1911456 Bionet2_000485 Cc1nnc(nc1O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G02 compound treatment 0.358 0.113 6.06 6.0556 1.0 1144806 Bionet2_000486 OCc1ccc(OCc2cnc(Cl)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G03 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911457 Bionet2_000487 Cc1ccc(Sc2nc(C)cc(C)c2S(=O)(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G04 compound treatment 0.25 0.00469 0.25 0.2519 1.0 1911458 Bionet2_000488 Clc1ccc(cc1)S(=O)(=O)Cn2nc(Br)nc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G05 compound treatment 0.228 -0.0173 -0.93 -0.9303 -1.0 1053289 Bionet2_000489 O=C(CC#N)N1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G06 compound treatment 0.345 0.0997 5.36 5.357 1.0 1266763 Bionet2_000490 COc1ccc(cc1)N2C(C(CN3CCN(C)CC3)C2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G07 compound treatment 0.24 -0.00531 -0.29 -0.2855 -1.0 1141263 Bionet2_000491 Cc1cc(nc2ccccc12)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G08 compound treatment 0.302 0.0567 3.05 3.0463 1.0 1911459 Bionet2_000492 OC(CS(=O)(=O)c1ccc(Br)cc1)c2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G09 compound treatment 0.292 0.0467 2.51 2.5089 1.0 1911460 Bionet2_000493 On1cc(nc(c2ccccc2)c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G10 compound treatment 0.334 0.0887 4.77 4.7659 1.0 1063001 Bionet2_000494 CCC(=O)c1ccc(OC)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G11 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911461 Bionet2_000495 c1ccn(c1)c2cnccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G12 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1731512 Bionet2_000496 Cc1ccn2c(CO)c(nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G13 compound treatment 0.263 0.0177 0.95 0.9505 1.0 1911462 Bionet2_000497 O(c1ccc(cc1)n2cccc2)c3ncccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G14 compound treatment 0.314 0.0687 3.69 3.6911 1.0 1338283 Bionet2_000498 OC(=O)c1ccc(Oc2ccc(Cl)c(F)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G15 compound treatment 0.381 0.136 7.29 7.2916 1.0 1911463 Bionet2_000499 OCc1cc(on1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G16 compound treatment 0.283 0.0377 2.03 2.0252 1.0 1595710 Bionet2_000500 Clc1ncc(CN2CCCc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G17 compound treatment 0.289 0.0437 2.35 2.3477 1.0 1911464 Bionet2_000501 O=C(Nc1ccccc1)OCc2cncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G18 compound treatment 0.414 0.169 9.06 9.0649 1.0 1911465 Bionet2_000502 N/C(=C\C#N)/c1ccc(Oc2ccc(Cl)c(F)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G19 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1911466 Bionet2_000503 Cc1cccc(CS(=O)(=O)c2nc[nH]n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G20 compound treatment 0.256 0.0107 0.57 0.5743 1.0 1219697 Bionet2_000504 COC(=O)C1CCN(CC1)C(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G21 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911467 Bionet2_000505 FC(F)(Br)C(F)(Br)CCS(=O)(=O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G22 compound treatment 0.264 0.0187 1.0 1.0042 1.0 1911468 Bionet2_000506 COc1cc(Br)cc(CO)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G23 mock treatment 0.248 0.00269 0.14 0.1444 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 G24 mock treatment 0.234 -0.0113 -0.61 -0.6079 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H01 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1466662 Bionet2_000507 OC(=O)c1cc2cc(Br)cc(Br)c2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H02 compound treatment 0.425 0.18 9.66 9.656 1.0 1360972 Bionet2_000508 O=C(NCc1cccnc1)c2cc(c[nH]2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H03 compound treatment 0.459 0.214 11.48 11.4831 1.0 1911469 Bionet2_000509 O=C1/C(=C/c2ccccc2)/COc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H04 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1911470 Bionet2_000510 FC(F)(F)C(CN1CCCCC1)OC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H05 compound treatment 0.289 0.0437 2.35 2.3477 1.0 1552920 Bionet2_000511 CCOC(=O)c1c(cn2ccccc12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H06 compound treatment 0.448 0.203 10.89 10.892 1.0 1911471 Bionet2_000512 Clc1ncc(COC(=O)/C=C/c2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H07 compound treatment 0.271 0.0257 1.38 1.3804 1.0 1216868 Bionet2_000513 OCC(Cc1ccccc1)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H08 compound treatment 0.24 -0.00531 -0.29 -0.2855 -1.0 1911472 Bionet2_000514 OC(=O)[C@@H]1CCCC[C@@H]1C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H09 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1911473 Bionet2_000515 OC(CNC1CCCCCC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H10 compound treatment 0.3 0.0547 2.94 2.9388 1.0 1911474 Bionet2_000516 CCc1cc(=O)[nH]c(SCc2ccc(F)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H11 compound treatment 0.297 0.0517 2.78 2.7776 1.0 1911475 Bionet2_000517 Clc1ccc(NC(=O)c2snnc2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H12 compound treatment 0.263 0.0177 0.95 0.9505 1.0 1911476 Bionet2_000518 COc1cccc(NC(=O)Cn2c(nc3ccccc23)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H13 compound treatment 0.535 0.29 15.57 15.5672 1.0 1911477 Bionet2_000519 COC(=O)/C=C/c1cnc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H14 compound treatment 0.421 0.176 9.44 9.4411 1.0 1911478 Bionet2_000520 Oc1ccc(cc1)c2nccc(n2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H15 compound treatment 0.237 -0.00831 -0.45 -0.4467 -1.0 1911479 Bionet2_000521 FC(F)(F)c1cccc(c1)C2NCCc3nc[nH]c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H16 compound treatment 0.359 0.114 6.11 6.1093 1.0 1911480 Bionet2_000522 Cc1ccccc1OC(=O)Cn2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H17 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911481 Bionet2_000523 COC(=O)Cn1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H18 compound treatment 0.244 -0.00131 -0.07 -0.0705 -1.0 1911482 Bionet2_000524 FC(F)(F)Oc1ccc(CN2CCS(=O)(=O)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H19 compound treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1687348 Bionet2_000525 OC(=O)C1CC=CCC1C(=O)Nc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H20 compound treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1911483 Bionet2_000526 Cc1cc(/C=C/C(=O)O)c(C)n1n2cnnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H21 compound treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1676297 Bionet2_000527 Cc1ccccc1c2nnc(c3ccccc3C)n2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H22 compound treatment 0.246 6.88E-4 0.04 0.0369 1.0 1712060 Bionet2_000528 CC(CC(=O)Nc1cccc(Cl)c1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H23 mock treatment 0.246 6.88E-4 0.04 0.0369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 H24 mock treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I01 compound treatment 0.236 -0.00931 -0.5 -0.5004 -1.0 1234759 Bionet2_000529 NC(=O)CN1C(=O)Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I02 compound treatment 0.391 0.146 7.83 7.8289 1.0 1911484 Bionet2_000530 Fc1cc(OCc2cnc(Cl)s2)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I03 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1911485 Bionet2_000531 Cc1ccc(cc1)C(=O)Cn2cccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I04 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1451816 Bionet2_000532 Cn1c(CO)cnc1S(=O)(=O)Cc2c(Cl)cccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I05 compound treatment 0.281 0.0357 1.92 1.9178 1.0 1911486 Bionet2_000533 N#Cc1ccsc1/N=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I06 compound treatment 0.311 0.0657 3.53 3.5299 1.0 1142650 Bionet2_000534 Cc1nc2sccn2c1C(=O)Nc3cc(C)cc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I07 compound treatment 0.481 0.236 12.67 12.6654 1.0 1911487 Bionet2_000535 CN(C)c1nc(nnc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I08 compound treatment 0.376 0.131 7.02 7.0229 1.0 1019508 Bionet2_000536 CCCC(=O)c1ccc(cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I09 compound treatment 0.255 0.00969 0.52 0.5206 1.0 1911488 Bionet2_000537 COc1ccsc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I10 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1911489 Bionet2_000538 CCCC1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I11 compound treatment 0.265 0.0197 1.06 1.058 1.0 1572212 Bionet2_000539 COc1ccc2ccccc2c1S(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I12 compound treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1911490 Bionet2_000540 Cc1ccc(Oc2ccc(C#N)cc2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I13 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1911491 Bionet2_000541 FC(=C(F)CCSC1=NCCN1)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I14 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1911492 Bionet2_000542 OC(CN1CCSCC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I15 compound treatment 0.407 0.162 8.69 8.6887 1.0 1911493 Bionet2_000543 ClCc1cc(on1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I16 compound treatment 0.288 0.0427 2.29 2.2939 1.0 1269738 Bionet2_000544 Clc1ncc(CN2CCc3ccccc3C2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I17 compound treatment 0.409 0.164 8.8 8.7962 1.0 1375357 Bionet2_000545 COc1ccc2c(C#N)c3ccccn3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I18 compound treatment 0.262 0.0167 0.9 0.8968 1.0 1911494 Bionet2_000546 Cc1ccc(C)n1c2ncc(Br)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I19 compound treatment 0.289 0.0437 2.35 2.3477 1.0 1911495 Bionet2_000547 CCC1CS/C(=N\c2cccc(c2)C(F)(F)F)/N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I20 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911496 Bionet2_000548 COC(=O)N1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I21 compound treatment 0.298 0.0527 2.83 2.8313 1.0 1911497 Bionet2_000549 COC(=O)c1ccc(Oc2ncc(cc2Cl)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I22 compound treatment 0.268 0.0227 1.22 1.2192 1.0 1911498 Bionet2_000550 CCOC(=O)c1ccc(/N=C/c2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I23 mock treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 I24 mock treatment 0.255 0.00969 0.52 0.5206 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J01 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1911499 Bionet2_000551 Fc1cccc(Cl)c1/C=C/2\N3CCC(CC3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J02 compound treatment 0.483 0.238 12.77 12.7728 1.0 1911500 Bionet2_000552 O=C(NCCCn1ccnc1)c2cc(c[nH]2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J03 compound treatment 0.246 6.88E-4 0.04 0.0369 1.0 1287139 Bionet2_000553 O=S1(=O)CCN(CC2CCCC2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J04 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911501 Bionet2_000554 C/C(=N\O)/c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J05 compound treatment 0.256 0.0107 0.57 0.5743 1.0 1544629 Bionet2_000555 CCC1NCCc2c1[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J06 compound treatment 0.388 0.143 7.67 7.6677 1.0 1911502 Bionet2_000556 Clc1ncc(COC(=O)c2cccc(Cl)c2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J07 compound treatment 0.378 0.133 7.13 7.1303 1.0 1243438 Bionet2_000557 OC(=O)c1cn2ccccc2c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J08 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1063672 Bionet2_000558 ClCCNC(=O)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J09 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911503 Bionet2_000559 OC(CN1CCN(CC1)c2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J10 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1911504 Bionet2_000560 FC(F)(F)c1cc(Cl)c2nnc(n2c1)C(F)(F)Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J11 compound treatment 0.426 0.181 9.71 9.7098 1.0 1911505 Bionet2_000561 CSc1cc(c(s1)C(=O)O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J12 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1911506 Bionet2_000562 FC(F)(F)c1nc2ccccc2n1CC(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J13 compound treatment 0.292 0.0467 2.51 2.5089 1.0 1911507 Bionet2_000563 O=C(CC#N)c1sccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J14 compound treatment 0.297 0.0517 2.78 2.7776 1.0 1911508 Bionet2_000564 FC(F)(F)C(CN1CCN(CC1)c2ccccc2)OC(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J15 compound treatment 0.409 0.164 8.8 8.7962 1.0 1911509 Bionet2_000565 Fc1ccc(Sc2cc(Cl)c(nn2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J16 compound treatment 0.334 0.0887 4.77 4.7659 1.0 1911510 Bionet2_000566 Cc1ccc(OC(=O)Cn2c(nc3ccccc23)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J17 compound treatment 0.515 0.27 14.49 14.4924 1.0 1911511 Bionet2_000567 CCOC(=O)c1cc(on1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J18 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911512 Bionet2_000568 OC(CNCc1ccc(OC(F)(F)F)cc1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J19 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911513 Bionet2_000569 Oc1ccc(/C=N\n2cnnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J20 compound treatment 0.343 0.0977 5.25 5.2495 1.0 1911514 Bionet2_000570 Brc1cc2OCOc2cc1/C=C/C(=O)N3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J21 compound treatment 0.394 0.149 7.99 7.9902 1.0 1911515 Bionet2_000571 CCN(C)C(=O)/C=C/c1cnc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J22 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1738886 Bionet2_000572 CC(CC(=O)Nc1ccc(C)cc1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J23 mock treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 J24 mock treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K01 compound treatment 0.328 0.0827 4.44 4.4435 1.0 1191772 Bionet2_000573 O=C(C1CC1c2ccccc2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K02 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911516 Bionet2_000574 NC(=O)/C=C\c1ccccc1Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K03 compound treatment 0.275 0.0297 1.6 1.5953 1.0 1911517 Bionet2_000575 C/[N+](=C\c1coc2ccccc2c1=O)/[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K04 compound treatment 0.412 0.167 8.96 8.9574 1.0 1911518 Bionet2_000576 Clc1ccc(NC=C2C(=O)CCCC2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K05 compound treatment 0.261 0.0157 0.84 0.843 1.0 1911519 Bionet2_000577 Cc1ccc(C)n1c2sccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K06 compound treatment 0.273 0.0277 1.49 1.4879 1.0 1911520 Bionet2_000578 OC(=O)c1cc(OCC=C)cc(OCC=C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K07 compound treatment 0.513 0.268 14.38 14.385 1.0 1911521 Bionet2_000579 CC(C)Nc1nc(nnc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K08 compound treatment 0.349 0.104 5.57 5.5719 1.0 1241498 Bionet2_000580 Cc1ccn2cc(nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K09 compound treatment 0.268 0.0227 1.22 1.2192 1.0 1689913 Bionet2_000581 C1CN(CCN1c2ccccc2)c3ncccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K10 compound treatment 0.268 0.0227 1.22 1.2192 1.0 1911522 Bionet2_000582 OC(=O)c1cccnc1SCCC(=C(F)F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K11 compound treatment 0.406 0.161 8.64 8.635 1.0 1911523 Bionet2_000583 Nc1ccc(Oc2ncccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K12 compound treatment 0.232 -0.0133 -0.72 -0.7154 -1.0 1911524 Bionet2_000584 Cc1cc(C)cc(Oc2ccccc2/C=N\O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K13 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1911525 Bionet2_000585 FC(=C(F)CCSc1nc[nH]n1)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K14 compound treatment 0.242 -0.00331 -0.18 -0.178 -1.0 1911526 Bionet2_000586 OC(CN1CCOCC1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K15 compound treatment 0.286 0.0407 2.19 2.1865 1.0 1388956 Bionet2_000587 Clc1cc(nc(n1)c2ccccc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K16 compound treatment 0.269 0.0237 1.27 1.2729 1.0 1911527 Bionet2_000588 FC(F)(F)c1ccc(N/C=C/2\C(=O)Oc3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K17 compound treatment 0.262 0.0167 0.9 0.8968 1.0 1911528 Bionet2_000589 FC(F)(F)c1cccc(CSc2nc[nH]n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K18 compound treatment 0.582 0.337 18.09 18.0929 1.0 1569120 Bionet2_000590 COc1cccc2cc(oc12)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K19 compound treatment 0.284 0.0387 2.08 2.079 1.0 1911529 Bionet2_000591 CC(C)(C)n1nc(c(C#N)c1N)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K20 compound treatment 0.276 0.0307 1.65 1.6491 1.0 1248139 Bionet2_000592 Nc1c(C#N)ncn1c2ccccc2Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K21 compound treatment 0.255 0.00969 0.52 0.5206 1.0 1911530 Bionet2_000593 CN(c1ncc(cc1Cl)C(F)(F)F)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K22 compound treatment 0.328 0.0827 4.44 4.4435 1.0 1911531 Bionet2_000594 COc1ccc(Oc2ccc(cc2)/C(=C/C#N)/N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K23 mock treatment 0.246 6.88E-4 0.04 0.0369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 K24 mock treatment 0.249 0.00369 0.2 0.1982 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L01 compound treatment 0.365 0.12 6.43 6.4318 1.0 1174601 Bionet2_000595 COc1ccc(Oc2ccccc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L02 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911532 Bionet2_000596 FC(F)(F)c1cccc(CN2CCS(=O)(=O)CC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L03 compound treatment 0.267 0.0217 1.17 1.1654 1.0 1195409 Bionet2_000597 COc1cccc2cc(oc12)C(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L04 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911533 Bionet2_000598 O[C@H](CSc1ncccn1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L05 compound treatment 0.27 0.0247 1.33 1.3267 1.0 1207575 Bionet2_000599 COC(=O)C(Cc1ccc(O)cc1)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L06 compound treatment 0.39 0.145 7.78 7.7752 1.0 1599619 Bionet2_000600 Clc1ncc(COc2ccc(CC#N)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L07 compound treatment 0.272 0.0267 1.43 1.4341 1.0 1911534 Bionet2_000601 Cc1nc2ccccc2nc1Oc3ccc(Cl)c(F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L08 compound treatment 0.322 0.0767 4.12 4.121 1.0 1309038 Bionet2_000602 CCc1cc(=O)[nH]c(SCc2cccc(Cl)c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L09 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911535 Bionet2_000603 OC(CN1CCc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L10 compound treatment 0.276 0.0307 1.65 1.6491 1.0 1911536 Bionet2_000604 COc1ccc(NC(=O)Cn2c(nc3ccccc23)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L11 compound treatment 0.246 6.88E-4 0.04 0.0369 1.0 1911537 Bionet2_000605 CC(C)(C)c1cc2cccnc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L12 compound treatment 0.316 0.0707 3.8 3.7986 1.0 1911538 Bionet2_000606 OC(=O)c1ccccc1NC(=O)Cn2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L13 compound treatment 0.256 0.0107 0.57 0.5743 1.0 1478498 Bionet2_000607 Cc1ccc(C)n1c2ccsc2C(=O)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L14 compound treatment 0.25 0.00469 0.25 0.2519 1.0 1650182 Bionet2_000608 CCN1CCN(CC1)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L15 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1911539 Bionet2_000609 COc1cnc(nc1Sc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L16 compound treatment 0.267 0.0217 1.17 1.1654 1.0 1911540 Bionet2_000610 FC(F)(F)c1nc2ccccc2n1CC(=O)Oc3ccc(C#N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L17 compound treatment 0.444 0.199 10.68 10.6771 1.0 1466521 Bionet2_000611 Oc1ccc(cc1)c2ncc3C(=O)CCCc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L18 compound treatment 0.436 0.191 10.25 10.2471 1.0 1155682 Bionet2_000612 Cc1cccc(n1)n2cnc(c2)C(=O)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L19 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911541 Bionet2_000613 C(=N/n1cnnc1)/c2ccsc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L20 compound treatment 0.24 -0.00531 -0.29 -0.2855 -1.0 1911542 Bionet2_000614 O=C(CNC(=O)/C(=C/c1cccs1)/c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L21 compound treatment 0.383 0.138 7.4 7.399 1.0 1682521 Bionet2_000615 Cc1ccc(cc1)C(=O)CSc2nccn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L22 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1207609 Bionet2_000616 CC(CC(=O)Nc1ccc(F)cc1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L23 mock treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 L24 mock treatment 0.233 -0.0123 -0.66 -0.6616 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M01 compound treatment 0.406 0.161 8.64 8.635 1.0 1324057 Bionet2_000617 COc1cccc(c1)C(=O)C2CC2c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M02 compound treatment 0.256 0.0107 0.57 0.5743 1.0 1911543 Bionet2_000618 Brc1nc(Br)n(Cc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M03 compound treatment 0.301 0.0557 2.99 2.9925 1.0 1911544 Bionet2_000619 O=C(NC(=S)n1nnc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M04 compound treatment 0.317 0.0717 3.85 3.8523 1.0 1911545 Bionet2_000620 Clc1cccc(NC=C2C(=O)CCCC2=O)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M05 compound treatment 0.286 0.0407 2.19 2.1865 1.0 1911546 Bionet2_000621 O=C(CSC1CCCCC1)Nc2sccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M06 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1157334 Bionet2_000622 CC(Oc1ccc(OCc2ccccc2)cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M07 compound treatment 0.362 0.117 6.27 6.2705 1.0 1911547 Bionet2_000623 Cc1nnc(nc1NC(C)(C)C)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M08 compound treatment 0.256 0.0107 0.57 0.5743 1.0 1034979 Bionet2_000624 c1c(cn2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M09 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911548 Bionet2_000625 CCOC(=O)C1=C(C)Nc2ccccc2S1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M10 compound treatment 0.3 0.0547 2.94 2.9388 1.0 1911549 Bionet2_000626 O/N=C/C1=C(Cl)c2ccccc2CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M11 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1911550 Bionet2_000627 C/C(=N\O)/c1cc(Cl)sc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M12 compound treatment 0.42 0.175 9.39 9.3873 1.0 1911551 Bionet2_000628 Clc1ccc2nc(cn2c1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M13 compound treatment 0.423 0.178 9.55 9.5486 1.0 1238208 Bionet2_000629 CC(=O)Nc1ccc(OCc2cnc(Cl)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M14 compound treatment 0.247 0.00169 0.09 0.0907 1.0 1911552 Bionet2_000630 OC(CNCCc1ccccn1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M15 compound treatment 0.291 0.0457 2.46 2.4552 1.0 1625342 Bionet2_000631 CCOC(=O)Cn1c(=O)cc(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M16 compound treatment 0.307 0.0617 3.31 3.315 1.0 1438344 Bionet2_000632 NNc1cccc2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M17 compound treatment 0.283 0.0377 2.03 2.0252 1.0 1911553 Bionet2_000633 COc1ccc(CSc2nc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M18 compound treatment 0.279 0.0337 1.81 1.8103 1.0 1118937 Bionet2_000634 Clc1ncc(CN2CCN(CC2)c3ccccc3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M19 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1180215 Bionet2_000635 CC(C)(C)n1nc(c2ccc(F)cc2)c3c(N)ncnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M20 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1911554 Bionet2_000636 OC/1C2CCN(CC2)\C1=C/c3ccccc3C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M21 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1911555 Bionet2_000637 COC(=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M22 compound treatment 0.27 0.0247 1.33 1.3267 1.0 1248523 Bionet2_000638 Fc1ccccc1Oc2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M23 mock treatment 0.252 0.00669 0.36 0.3594 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 M24 mock treatment 0.244 -0.00131 -0.07 -0.0705 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N01 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1546166 Bionet2_000639 CC(=O)Nc1[nH]cc(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N02 compound treatment 0.257 0.0117 0.63 0.6281 1.0 1911556 Bionet2_000640 FC(F)(F)c1ccc(CON2CCS(=O)(=O)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N03 compound treatment 0.257 0.0117 0.63 0.6281 1.0 1911557 Bionet2_000641 OC(CNCc1ccccc1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N04 compound treatment 0.451 0.206 11.05 11.0532 1.0 1911558 Bionet2_000642 Clc1ncc(COC(=O)c2ccccc2Cl)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N05 compound treatment 0.267 0.0217 1.17 1.1654 1.0 1060056 Bionet2_000643 OC(=O)CCCSc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N06 compound treatment 0.269 0.0237 1.27 1.2729 1.0 1911559 Bionet2_000644 COc1cnc(nc1Oc2ccc(Cl)cc2C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N07 compound treatment 0.291 0.0457 2.46 2.4552 1.0 1911560 Bionet2_000645 Fc1ccccc1/C=C\2/C(OC(=O)c3ccccc3)C4CCN2CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N08 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911561 Bionet2_000646 Clc1ccc(CNC(=O)Cn2cnnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N09 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1911562 Bionet2_000647 CCSc1ncc(CO)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N10 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911563 Bionet2_000648 Cc1ccc(NC(=O)Cn2c(nc3ccccc23)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N11 compound treatment 0.493 0.248 13.31 13.3102 1.0 1911564 Bionet2_000649 C(Sc1ccccc1)c2cc(no2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N12 compound treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1911565 Bionet2_000650 Cc1ccc(C)n1n2cnnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N13 compound treatment 0.244 -0.00131 -0.07 -0.0705 -1.0 1718863 Bionet2_000651 OC(=O)c1sccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N14 compound treatment 0.316 0.0707 3.8 3.7986 1.0 1259363 Bionet2_000652 CCOC(=O)c1c(cn2ccccc12)c3cccc(N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N15 compound treatment 0.335 0.0897 4.82 4.8196 1.0 1712048 Bionet2_000653 OC(=O)c1csc(Cc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N16 compound treatment 0.325 0.0797 4.28 4.2822 1.0 1911566 Bionet2_000654 C/C(=C/C(=O)c1ccccc1)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N17 compound treatment 0.461 0.216 11.59 11.5906 1.0 1911567 Bionet2_000655 O=C(/C=C/c1ccc(OCc2ccccc2)cc1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N18 compound treatment 0.272 0.0267 1.43 1.4341 1.0 1553441 Bionet2_000656 CCOC(=O)NC(C1CCc2ccccc2C1=O)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N19 compound treatment 0.243 -0.00231 -0.12 -0.1243 -1.0 1705595 Bionet2_000657 OC(=O)c1ccccc1N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N20 compound treatment 0.263 0.0177 0.95 0.9505 1.0 1238663 Bionet2_000658 Fc1ccc(cc1)C(=O)c2c[nH]c(c2)C(=O)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N21 compound treatment 0.238 -0.00731 -0.39 -0.393 -1.0 1460232 Bionet2_000659 OC(=O)C1CC=CCC1C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N22 compound treatment 0.244 -0.00131 -0.07 -0.0705 -1.0 1911568 Bionet2_000660 Cc1cc2ncc(c(c3ccccc3)n2n1)n4cncn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N23 mock treatment 0.24 -0.00531 -0.29 -0.2855 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 N24 mock treatment 0.241 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O01 compound treatment 0.29 0.0447 2.4 2.4014 1.0 1911569 Bionet2_000661 COc1ccc(cc1)C2CC2/C(=N/O)/c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O02 compound treatment 0.245 -3.12E-4 -0.02 -0.0168 -1.0 1911570 Bionet2_000662 CCC1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O03 compound treatment 0.289 0.0437 2.35 2.3477 1.0 1549837 Bionet2_000663 OCC(N1Cc2ccccc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O04 compound treatment 0.266 0.0207 1.11 1.1117 1.0 1911571 Bionet2_000664 O=C1CCCc2ccccc2N1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O05 compound treatment 0.316 0.0707 3.8 3.7986 1.0 1911572 Bionet2_000665 Cc1ccc(/C=N/c2sccc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O06 compound treatment 0.237 -0.00831 -0.45 -0.4467 -1.0 1911573 Bionet2_000666 Oc1ccc(c(F)c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O07 compound treatment 0.328 0.0827 4.44 4.4435 1.0 1911574 Bionet2_000667 CC(C)(C)c1cc(c(C#N)c(O)n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O08 compound treatment 0.268 0.0227 1.22 1.2192 1.0 1911575 Bionet2_000668 CC(=O)OCc1ccccc1Oc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O09 compound treatment 0.25 0.00469 0.25 0.2519 1.0 1911576 Bionet2_000669 Fc1ccc(cc1)n2nccc2c3cc(Cl)sc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O10 compound treatment 0.33 0.0847 4.55 4.5509 1.0 1579747 Bionet2_000670 CCOC(=O)c1c(O)c2cccc3CCn(c1=O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O11 compound treatment 0.255 0.00969 0.52 0.5206 1.0 1146048 Bionet2_000671 O=C(N1CCCc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O12 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1911577 Bionet2_000672 COc1ccc(OC)c2[nH]c(nc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O13 compound treatment 0.425 0.18 9.66 9.656 1.0 1911578 Bionet2_000673 Clc1ncc(COc2ccc(C#N)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O14 compound treatment 0.256 0.0107 0.57 0.5743 1.0 1911579 Bionet2_000674 OC(CNCc1ccc(Cl)cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O15 compound treatment 0.279 0.0337 1.81 1.8103 1.0 1606339 Bionet2_000675 N#CCOc1ccc2c(C#N)c3ccccn3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O16 compound treatment 0.258 0.0127 0.68 0.6818 1.0 1911580 Bionet2_000676 Cc1nc(cs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O17 compound treatment 0.252 0.00669 0.36 0.3594 1.0 1911581 Bionet2_000677 Cc1ccc(CS(=O)(=O)c2nc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O18 compound treatment 0.25 0.00469 0.25 0.2519 1.0 2281 Bionet2_000678 NC(=N)SCc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O19 compound treatment 0.355 0.11 5.89 5.8944 1.0 1911582 Bionet2_000679 CCOC(=O)/C=C\1/C(=O)N(CC=C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O20 compound treatment 0.259 0.0137 0.74 0.7355 1.0 1911583 Bionet2_000680 Nc1ccc(N2CCOCC2)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O21 compound treatment 0.248 0.00269 0.14 0.1444 1.0 1911584 Bionet2_000681 CCOC(=O)CC1C(=O)C=Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O22 compound treatment 0.313 0.0677 3.64 3.6374 1.0 1911585 Bionet2_000682 Cc1ccc(cc1)C(=O)Nc2ncc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O23 mock treatment 0.256 0.0107 0.57 0.5743 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 O24 mock treatment 0.257 0.0117 0.63 0.6281 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P01 compound treatment 0.278 0.0327 1.76 1.7566 1.0 1643658 Bionet2_000683 Fc1cc(OC(=O)c2ccco2)ccc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P02 compound treatment 0.28 0.0347 1.86 1.864 1.0 1911586 Bionet2_000684 COC(=O)Cc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P03 compound treatment 0.311 0.0657 3.53 3.5299 1.0 1365217 Bionet2_000685 COC(=O)c1cn(cn1)c2cccc(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P04 compound treatment 0.361 0.116 6.22 6.2168 1.0 1911587 Bionet2_000686 NNc1ccc(cn1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P05 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911588 Bionet2_000687 FC(F)(F)c1ccccc1CN2CCS(=O)(=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P06 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911589 Bionet2_000688 CCOC(=O)c1cnn(c1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P07 compound treatment 0.25 0.00469 0.25 0.2519 1.0 1911590 Bionet2_000689 CC(NCC(O)C(F)(F)F)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P08 compound treatment 0.31 0.0647 3.48 3.4762 1.0 1911591 Bionet2_000690 Cc1ccc(cc1)c2ccnc(n2)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P09 compound treatment 0.338 0.0927 4.98 4.9808 1.0 1097870 Bionet2_000691 Clc1ccc(CN2COc3c(C2)cc(Cl)c4cccnc34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P10 compound treatment 0.261 0.0157 0.84 0.843 1.0 1911592 Bionet2_000692 Cc1cccc(NC(=O)Cn2c(nc3ccccc23)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P11 compound treatment 0.468 0.223 11.97 11.9668 1.0 1194912 Bionet2_000693 O=C(Cc1ccccc1)c2c[nH]c(c2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P12 compound treatment 0.254 0.00869 0.47 0.4668 1.0 1911593 Bionet2_000694 Cc1ccc(C)n1NC(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P13 compound treatment 0.253 0.00769 0.41 0.4131 1.0 1911594 Bionet2_000695 CCOC(=O)c1c(C)nn(C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P14 compound treatment 0.284 0.0387 2.08 2.079 1.0 1911595 Bionet2_000696 CCc1cc(=O)[nH]c(SCc2ccc(C)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P15 compound treatment 0.249 0.00369 0.2 0.1982 1.0 1911596 Bionet2_000697 Clc1ccc(cc1)c2cnc(Oc3ccccc3)nc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P16 compound treatment 0.267 0.0217 1.17 1.1654 1.0 1612730 Bionet2_000698 CC(C)N1CCN(CC1)c2ccc(NC(=O)c3cccc(C)c3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P17 compound treatment 0.279 0.0337 1.81 1.8103 1.0 1377111 Bionet2_000699 CC(O)c1ccc(OCc2c(F)cccc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P18 compound treatment 0.327 0.0817 4.39 4.3897 1.0 1074507 Bionet2_000700 COc1ccc2[nH]c(cc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P19 compound treatment 0.226 -0.0193 -1.04 -1.0378 -1.0 1911597 Bionet2_000701 O=C1C2CC=CCC2C(=O)N1CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P20 compound treatment 0.257 0.0117 0.63 0.6281 1.0 1311050 Bionet2_000702 Fc1ccc(cc1)C(=O)c2c[nH]c(c2)C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P21 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911598 Bionet2_000703 FC(F)(F)c1cc(Nc2ccccc2C#N)ccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P22 compound treatment 0.251 0.00569 0.31 0.3056 1.0 1911599 Bionet2_000704 O=C(NCc1cccs1)/C(=C/c2cccs2)/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P23 mock treatment 0.239 -0.00631 -0.34 -0.3392 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1365 P24 mock treatment 0.246 6.88E-4 0.04 0.0369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A01 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1185045 Bionet2_000705 O=C(N1CCOCC1)c2cnc(nc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A02 compound treatment 0.221 -0.0228 -1.23 -1.2256 -1.0 1911600 Bionet2_000706 CCCNC(=O)c1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A03 compound treatment 0.213 -0.0308 -1.66 -1.6555 -1.0 1661792 Bionet2_000707 CC1N(C(=O)c2ccccc2)c3ccccc3NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A04 compound treatment 0.234 -0.00981 -0.53 -0.527 -1.0 1911601 Bionet2_000708 FC(F)(F)c1nc2ccccc2nc1NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A05 compound treatment 0.222 -0.0218 -1.17 -1.1718 -1.0 1215538 Bionet2_000709 CC1N(C(=O)C2CC2)c3ccccc3NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A06 compound treatment 0.272 0.0282 1.52 1.5151 1.0 1727894 Bionet2_000710 C(Sc1ccccc1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A07 compound treatment 0.226 -0.0178 -0.96 -0.9569 -1.0 1911602 Bionet2_000711 FC(F)(F)c1cnc(N2CCC(=O)CC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A08 compound treatment 0.201 -0.0428 -2.3 -2.3003 -1.0 1911603 Bionet2_000712 FC(F)(F)c1cnc(Oc2ccccc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A09 compound treatment 0.228 -0.0158 -0.85 -0.8494 -1.0 1911604 Bionet2_000713 FC(F)(F)c1cnc(c(Cl)c1)C(C#N)(N2CCOCC2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A10 compound treatment 0.275 0.0312 1.68 1.6763 1.0 1911605 Bionet2_000714 Clc1cc2nc([nH]c2cc1Cl)c3ccc(=O)[nH]c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A11 compound treatment 0.345 0.101 5.44 5.4379 1.0 1911606 Bionet2_000715 NC(=O)C(c1ccc(F)cc1)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A12 compound treatment 0.22 -0.0238 -1.28 -1.2793 -1.0 1431993 Bionet2_000716 CNC1C(CO)COc2c(OC)cccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A13 compound treatment 0.224 -0.0198 -1.06 -1.0644 -1.0 1911607 Bionet2_000717 CN(C)C(=O)c1cccn1c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A14 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911608 Bionet2_000718 NC(=O)c1ncc(cc1SCc2ccc(Cl)cc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A15 compound treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1251524 Bionet2_000719 NC(=O)C(c1ccccc1)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A16 compound treatment 0.229 -0.0148 -0.8 -0.7957 -1.0 1911609 Bionet2_000720 FC(F)(F)c1c(C#N)cnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A17 compound treatment 0.27 0.0262 1.41 1.4076 1.0 1911610 Bionet2_000721 [O-][n+]1ccccc1Sc2nnc(Cc3ccccc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A18 compound treatment 0.246 0.00219 0.12 0.1179 1.0 1405187 Bionet2_000722 C=CCNC(=O)C1CCN(CC1)c2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A19 compound treatment 0.226 -0.0178 -0.96 -0.9569 -1.0 1332134 Bionet2_000723 NOCC(=O)N1CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A20 compound treatment 0.246 0.00219 0.12 0.1179 1.0 1911611 Bionet2_000724 O=C1CCCN1c2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A21 compound treatment 0.249 0.00519 0.28 0.2791 1.0 1911612 Bionet2_000725 CSc1ncc(cn1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A22 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1433879 Bionet2_000726 OC(=O)CN1Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A23 mock treatment 0.236 -0.00781 -0.42 -0.4195 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 A24 mock treatment 0.253 0.00919 0.49 0.494 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B01 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1667566 Bionet2_000727 Clc1ccccc1NC(=O)CC(=O)Nc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B02 compound treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1911613 Bionet2_000728 Clc1ccc(CC(=O)NCCSc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B03 compound treatment 0.278 0.0342 1.84 1.8375 1.0 1136659 Bionet2_000729 COc1ccc(cc1)c2cc(n[nH]2)C3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B04 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1911614 Bionet2_000730 OCCCc1c[nH]nc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B05 compound treatment 0.226 -0.0178 -0.96 -0.9569 -1.0 1134786 Bionet2_000731 Cc1onc(c1C(=O)NCC=C)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B06 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1197198 Bionet2_000732 OC(=O)Cc1cn(Cc2ccc(F)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B07 compound treatment 0.289 0.0452 2.43 2.4286 1.0 1911615 Bionet2_000733 FC(F)(F)c1cccc(c1)c2nc(no2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B08 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1708823 Bionet2_000734 OCc1cccnc1Sc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B09 compound treatment 0.376 0.132 7.1 7.1038 1.0 1911616 Bionet2_000735 c1snnc1c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B10 compound treatment 0.324 0.0802 4.31 4.3094 1.0 1025707 Bionet2_000736 BrCC(=O)c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B11 compound treatment 0.469 0.225 12.1 12.1014 1.0 1911617 Bionet2_000737 FC(F)(F)c1cnc(NCCn2c(=O)c(=O)[nH]c3cccc(Cl)c23)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B12 compound treatment 0.262 0.0182 0.98 0.9777 1.0 1911618 Bionet2_000738 CCOC(=O)Oc1cc(N)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B13 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911619 Bionet2_000739 Cc1c(Cl)cccc1N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B14 compound treatment 0.321 0.0772 4.15 4.1482 1.0 1311802 Bionet2_000740 Cc1cc([nH]c(=O)c1S(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B15 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1444188 Bionet2_000741 CC1(C)CN(C1=O)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B16 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1237794 Bionet2_000742 CCOC(=O)C1=C(C)NC(=O)CC1c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B17 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1489840 Bionet2_000743 CC(=O)Nc1ccc(cc1)N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B18 compound treatment 0.256 0.0122 0.66 0.6553 1.0 1911620 Bionet2_000744 Cc1cccc(/N=C/2\C(=O)N(c3ccccc23)c4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B19 compound treatment 0.367 0.123 6.62 6.6202 1.0 1911621 Bionet2_000745 CCOc1cnc(o1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B20 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1911622 Bionet2_000746 Cc1ccc(/N=C/2\C(=O)N(CC=C)c3ccccc23)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B21 compound treatment 0.274 0.0302 1.62 1.6225 1.0 1911623 Bionet2_000747 Nc1nc(cs1)c2sccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B22 compound treatment 0.42 0.176 9.47 9.4683 1.0 1911624 Bionet2_000748 O=C(/C=C/C=C/c1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B23 mock treatment 0.279 0.0352 1.89 1.8912 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 B24 mock treatment 0.232 -0.0118 -0.63 -0.6345 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C01 compound treatment 0.241 -0.00281 -0.15 -0.1508 -1.0 1417116 Bionet2_000749 CN(C)C(=O)c1cnc(nc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C02 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1014160 Bionet2_000750 CC(C)C(=O)Nc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C03 compound treatment 0.282 0.0382 2.05 2.0524 1.0 1911625 Bionet2_000751 FC(F)(F)c1cccc(c1)c2nnnn2c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C04 compound treatment 0.245 0.00119 0.06 0.0641 1.0 1911626 Bionet2_000752 CN(N)c1nc2ccccc2nc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C05 compound treatment 0.296 0.0522 2.8 2.8048 1.0 1205172 Bionet2_000753 Cc1[nH]c(=O)c(C#N)cc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C06 compound treatment 0.267 0.0232 1.25 1.2464 1.0 1275385 Bionet2_000754 CC(C)(C)c1cc(c(C#N)c(N)n1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C07 compound treatment 0.325 0.0812 4.36 4.3632 1.0 1911627 Bionet2_000755 O/N=C/c1c(OCC=C)ccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C08 compound treatment 0.379 0.135 7.27 7.265 1.0 1911628 Bionet2_000756 FC(F)(F)c1cnc2c(onc2c1)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C09 compound treatment 0.231 -0.0128 -0.69 -0.6882 -1.0 1911629 Bionet2_000757 Cc1cc(C)n(n1)C2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C10 compound treatment 0.47 0.226 12.16 12.1552 1.0 1911630 Bionet2_000758 Cc1ccc(cc1)S(=O)(=O)c2c(CO)c(nn2C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C11 compound treatment 0.254 0.0102 0.55 0.5478 1.0 1911631 Bionet2_000759 Cn1cccc1C(C#N)c2cccc(F)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C12 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1285814 Bionet2_000760 NC1C(CO)COc2ccc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C13 compound treatment 0.229 -0.0148 -0.8 -0.7957 -1.0 1911632 Bionet2_000761 NC(=O)c1cccn1c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C14 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1911633 Bionet2_000762 Cc1cc(Cl)ccc1Oc2cc(cnc2C#N)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C15 compound treatment 0.34 0.0962 5.17 5.1692 1.0 1911634 Bionet2_000763 Fc1cccc(C(C#N)c2ccc(Cl)cc2Cl)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C16 compound treatment 0.264 0.0202 1.09 1.0852 1.0 1150439 Bionet2_000764 CC(C)(C)C1=C(C#N)C(CC(=O)N1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C17 compound treatment 0.516 0.272 14.63 14.6271 1.0 1911635 Bionet2_000765 O=c1c(cnc2sc3ccccc3n12)c4ccn[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C18 compound treatment 0.345 0.101 5.44 5.4379 1.0 1151100 Bionet2_000766 O=C1CC(CC(=O)C1CS(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C19 compound treatment 0.257 0.0132 0.71 0.709 1.0 1142660 Bionet2_000767 COc1ccccc1NC(=O)CON 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C20 compound treatment 0.359 0.115 6.19 6.1903 1.0 1127981 Bionet2_000768 Clc1ccc(C(=O)c2ccc(CC#N)s2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C21 compound treatment 0.409 0.165 8.88 8.8772 1.0 1911636 Bionet2_000769 C=CCSc1ncc(cn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C22 compound treatment 0.249 0.00519 0.28 0.2791 1.0 1241924 Bionet2_000770 CCCN(CCC)c1cc(Cl)nc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C23 mock treatment 0.254 0.0102 0.55 0.5478 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 C24 mock treatment 0.242 -0.00181 -0.1 -0.0971 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D01 compound treatment 0.27 0.0262 1.41 1.4076 1.0 1322387 Bionet2_000771 Fc1ccc(NC(=O)CC(=O)Nc2ccc(F)cc2F)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D02 compound treatment 0.37 0.126 6.78 6.7814 1.0 1157641 Bionet2_000772 CCOC(=O)c1cc(C#N)c(=O)[nH]c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D03 compound treatment 0.317 0.0732 3.93 3.9333 1.0 1650034 Bionet2_000773 Clc1ccc(c2cc([nH]n2)C3CCNCC3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D04 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911637 Bionet2_000774 Nc1ccccc1NC2=CC(=O)CC(C2)c3c(F)cccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D05 compound treatment 0.271 0.0272 1.46 1.4613 1.0 1168412 Bionet2_000775 Clc1cccc(Cl)c1c2nocc2C(=O)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D06 compound treatment 0.319 0.0752 4.04 4.0407 1.0 1374440 Bionet2_000776 OC(=O)Cc1cn(c2ccc(Cl)nn2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D07 compound treatment 0.234 -0.00981 -0.53 -0.527 -1.0 1911638 Bionet2_000777 NC(C(=O)O)c1ccsc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D08 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1911639 Bionet2_000778 Cn1nc(CSc2ccccc2)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D09 compound treatment 0.234 -0.00981 -0.53 -0.527 -1.0 1098138 Bionet2_000779 c1snnc1c2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D10 compound treatment 0.263 0.0192 1.03 1.0314 1.0 1292550 Bionet2_000780 NCC(O)c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D11 compound treatment 0.375 0.131 7.05 7.0501 1.0 1911640 Bionet2_000781 COC(=O)CCCNc1ccc(cc1N)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D12 compound treatment 0.239 -0.00481 -0.26 -0.2583 -1.0 1911641 Bionet2_000782 OC(=O)/C=C(\C#N)/c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D13 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1911642 Bionet2_000783 Cc1cc(C)cc(c1)N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D14 compound treatment 0.43 0.186 10.01 10.0057 1.0 1348303 Bionet2_000784 Cc1ccc(cc1)S(=O)(=O)c2c(C)cc(C)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D15 compound treatment 0.406 0.162 8.72 8.7159 1.0 1911643 Bionet2_000785 CC1(C)CN(C1=O)c2ccc(I)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D16 compound treatment 0.233 -0.0108 -0.58 -0.5807 -1.0 1911644 Bionet2_000786 CCOC(=O)C1=C(C)NC(=O)CC1c2ccccc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D17 compound treatment 0.298 0.0542 2.91 2.9122 1.0 1911645 Bionet2_000787 Nc1ccc(Sc2cccc(c2)C(F)(F)F)c(C#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D18 compound treatment 0.294 0.0502 2.7 2.6973 1.0 1911646 Bionet2_000788 CCOc1ccc(/N=C/2\C(=O)N(c3ccccc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D19 compound treatment 0.469 0.225 12.1 12.1014 1.0 1911647 Bionet2_000789 Oc1cc(=O)sc(n1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D20 compound treatment 0.442 0.198 10.65 10.6505 1.0 1911648 Bionet2_000790 CN1C(=O)/C(=N/c2ccc(C)cc2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D21 compound treatment 0.428 0.184 9.9 9.8982 1.0 1911649 Bionet2_000791 O=C(N/C=C/c1ccco1)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D22 compound treatment 0.26 0.0162 0.87 0.8702 1.0 1346525 Bionet2_000792 CC(=O)Nc1ccc(I)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D23 mock treatment 0.26 0.0162 0.87 0.8702 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 D24 mock treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E01 compound treatment 0.239 -0.00481 -0.26 -0.2583 -1.0 1041337 Bionet2_000793 Clc1ccc(OCCBr)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E02 compound treatment 0.273 0.0292 1.57 1.5688 1.0 1911650 Bionet2_000794 Clc1cccc(c1)c2nnnn2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E03 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1911651 Bionet2_000795 Brc1ccc(cc1)S(=O)(=O)CCNC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E04 compound treatment 0.322 0.0782 4.2 4.202 1.0 1911652 Bionet2_000796 Oc1nc2ccccc2nc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E05 compound treatment 0.473 0.229 12.32 12.3164 1.0 1639658 Bionet2_000797 CCCn1cnc2c(N)c(C)c(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E06 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1128775 Bionet2_000798 Cc1nc2cc(Cl)ccc2c(=O)n1c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E07 compound treatment 0.229 -0.0148 -0.8 -0.7957 -1.0 1650032 Bionet2_000799 COc1cccc2[C@H]3[C@H](CON3C)COc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E08 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1574950 Bionet2_000800 CCOC(=O)c1[nH]c2ccccc2c1n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E09 compound treatment 0.232 -0.0118 -0.63 -0.6345 -1.0 1911653 Bionet2_000801 FC(F)(F)c1cc(c2ccc3nnnn3c2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E10 compound treatment 0.22 -0.0238 -1.28 -1.2793 -1.0 1911654 Bionet2_000802 CN(C)S(=O)(=O)c1c(C)nn(C)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E11 compound treatment 0.264 0.0202 1.09 1.0852 1.0 1911655 Bionet2_000803 Fc1cccc(C(C#N)c2cccs2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E12 compound treatment 0.407 0.163 8.77 8.7697 1.0 1911656 Bionet2_000804 Fc1ccc(cc1)c2onc3ccc(cc23)c4cc[nH]n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E13 compound treatment 0.242 -0.00181 -0.1 -0.0971 -1.0 1911657 Bionet2_000805 Nc1nc(Br)c2c(F)cccc2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E14 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1911658 Bionet2_000806 Oc1ccc(Oc2cc(cnc2C#N)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E15 compound treatment 0.388 0.144 7.75 7.7487 1.0 1225558 Bionet2_000807 O=C(c1ccccc1)c2ccc(cc2)C(C#N)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E16 compound treatment 0.299 0.0552 2.97 2.966 1.0 1911659 Bionet2_000808 COC(=O)C(CC(=O)c1ccc(Br)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E17 compound treatment 0.443 0.199 10.7 10.7042 1.0 1911660 Bionet2_000809 O=C1N(Cc2ccccc2)Cc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E18 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1911661 Bionet2_000810 FC(F)(F)c1cnc(c(Cl)c1)n2ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E19 compound treatment 0.522 0.278 14.95 14.9495 1.0 1618454 Bionet2_000811 Oc1ccc(cc1)c2cc3C(=O)c4ccccc4-c3nn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E20 compound treatment 0.307 0.0632 3.4 3.3959 1.0 1911662 Bionet2_000812 ClCCCC(=O)Nc1ccc(Cl)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E21 compound treatment 0.489 0.245 13.18 13.1762 1.0 1280821 Bionet2_000813 COC(=O)c1ccc2OCc3ccccc3C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E22 compound treatment 0.267 0.0232 1.25 1.2464 1.0 1911663 Bionet2_000814 CCN(CC)c1cc(Cl)nc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E23 mock treatment 0.267 0.0232 1.25 1.2464 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 E24 mock treatment 0.244 1.94E-4 0.01 0.0104 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F01 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1911664 Bionet2_000815 Cn1nc(c(C(O)c2cccs2)c1Cl)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F02 compound treatment 0.327 0.0832 4.47 4.4706 1.0 1605697 Bionet2_000816 CSc1cc([nH]c(=O)c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F03 compound treatment 0.395 0.151 8.12 8.1248 1.0 1521922 Bionet2_000817 Clc1ccc(c2cc(n[nH]2)C3CCN(CC#N)CC3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F04 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1911665 Bionet2_000818 Cc1cc2ncc(cn2n1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F05 compound treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1283933 Bionet2_000819 COc1ccccc1C(=O)NC(C)(C)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F06 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1911666 Bionet2_000820 FC(F)(F)c1cnc(ON2C(=O)CCC2=O)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F07 compound treatment 0.248 0.00419 0.23 0.2254 1.0 1911667 Bionet2_000821 NC(C(=O)O)c1ccccc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F08 compound treatment 0.288 0.0442 2.37 2.3749 1.0 1911668 Bionet2_000822 Cn1nc(CSc2ccc(Cl)cc2)c(CO)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F09 compound treatment 0.314 0.0702 3.77 3.7721 1.0 1911669 Bionet2_000823 Oc1ccccc1c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F10 compound treatment 0.335 0.0912 4.9 4.9006 1.0 1667231 Bionet2_000824 OC(CNC(=O)c1c(F)cccc1F)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F11 compound treatment 0.45 0.206 11.08 11.0804 1.0 1911670 Bionet2_000825 Fc1ccc(SCC(=O)NCCSc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F12 compound treatment 0.261 0.0172 0.92 0.9239 1.0 1911671 Bionet2_000826 OC(=O)/C=C(\C#N)/c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F13 compound treatment 0.263 0.0192 1.03 1.0314 1.0 1454325 Bionet2_000827 CC1(C)CN(C1=O)c2ccc(Cl)cc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F14 compound treatment 0.3 0.0562 3.02 3.0197 1.0 1911672 Bionet2_000828 CC1=C(C#N)/C(=C/Nc2ccc(F)cc2)/CC(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F15 compound treatment 0.223 -0.0208 -1.12 -1.1181 -1.0 1911673 Bionet2_000829 COC(=O)c1ccccc1N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F16 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1143091 Bionet2_000830 CC(C)Oc1cc(N2C(=O)CSCC2=O)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F17 compound treatment 0.293 0.0492 2.64 2.6436 1.0 1911674 Bionet2_000831 O=S(Cc1cc(Sc2ccccc2)nc(n1)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F18 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1911675 Bionet2_000832 Cc1noc(C)c1CSc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F19 compound treatment 0.473 0.229 12.32 12.3164 1.0 1911676 Bionet2_000833 CC(C)c1ccc(cc1)c2nc(O)cc(=O)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F20 compound treatment 0.247 0.00319 0.17 0.1716 1.0 1911677 Bionet2_000834 Nc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F21 compound treatment 0.393 0.149 8.02 8.0173 1.0 1911678 Bionet2_000835 COc1ccc(COC(=O)N/C=C/c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F22 compound treatment 0.278 0.0342 1.84 1.8375 1.0 1911679 Bionet2_000836 CC(C)c1ccc(/C=C/C(=O)CCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F23 mock treatment 0.246 0.00219 0.12 0.1179 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 F24 mock treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G01 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1010293 Bionet2_000837 OC(=O)CCSc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G02 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911680 Bionet2_000838 CC(C)C(=O)Nc1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G03 compound treatment 0.338 0.0942 5.06 5.0618 1.0 1911681 Bionet2_000839 FC(F)(F)c1cnc(c(Cl)c1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G04 compound treatment 0.285 0.0412 2.21 2.2137 1.0 1911682 Bionet2_000840 FC(F)(F)c1ccc(cc1)c2noc(n2)c3ccc(Cl)nc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G05 compound treatment 0.253 0.00919 0.49 0.494 1.0 1911683 Bionet2_000841 Cc1nc(Cl)c(C#N)cc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G06 compound treatment 0.241 -0.00281 -0.15 -0.1508 -1.0 1911684 Bionet2_000842 Cc1nc2cc(Cl)ccc2c(=O)n1c3nc[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G07 compound treatment 0.242 -0.00181 -0.1 -0.0971 -1.0 1911685 Bionet2_000843 C/C(=N/O)/c1cn(c(C)n1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G08 compound treatment 0.241 -0.00281 -0.15 -0.1508 -1.0 1911686 Bionet2_000844 Cc1nn(c(C)c1CS(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G09 compound treatment 0.517 0.273 14.68 14.6809 1.0 1742992 Bionet2_000845 COc1ccc(cc1)N2CC(=CC2=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G10 compound treatment 0.233 -0.0108 -0.58 -0.5807 -1.0 1489570 Bionet2_000846 Clc1ncccc1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G11 compound treatment 0.242 -0.00181 -0.1 -0.0971 -1.0 1911687 Bionet2_000847 O/N=C/c1cccn1c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G12 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1221254 Bionet2_000848 COc1ccccc1c2c(C#N)c(C)nc(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G13 compound treatment 0.359 0.115 6.19 6.1903 1.0 1911688 Bionet2_000849 COC(=O)/C=C/c1cc2ccccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G14 compound treatment 0.262 0.0182 0.98 0.9777 1.0 1911689 Bionet2_000850 FC(F)(F)c1cnc(C#N)c(OCc2ccccc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G15 compound treatment 0.253 0.00919 0.49 0.494 1.0 1668220 Bionet2_000851 O=C1NC(=O)c2ccccc2C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G16 compound treatment 0.256 0.0122 0.66 0.6553 1.0 1385271 Bionet2_000852 OC(=O)C(CC(=O)c1ccccc1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G17 compound treatment 0.51 0.266 14.3 14.3047 1.0 1715190 Bionet2_000853 COC(=O)CSc1cccc2C(CC(=O)c21)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G18 compound treatment 0.305 0.0612 3.29 3.2884 1.0 1911690 Bionet2_000854 FC(F)(F)c1cnc(c(Cl)c1)n2cc(C3OCCO3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G19 compound treatment 0.473 0.229 12.32 12.3164 1.0 1911691 Bionet2_000855 Cc1ccc(o1)c2ccnc3nc(nn23)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G20 compound treatment 0.275 0.0312 1.68 1.6763 1.0 1911692 Bionet2_000856 C/C(=N\O)/c1ccccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G21 compound treatment 0.263 0.0192 1.03 1.0314 1.0 1911693 Bionet2_000857 Clc1ccc(cc1)C(Sc2ccccc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G22 compound treatment 0.248 0.00419 0.23 0.2254 1.0 1145602 Bionet2_000858 O=C(CC(=O)Nc1ccccn1)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G23 mock treatment 0.25 0.00619 0.33 0.3328 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 G24 mock treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H01 compound treatment 0.239 -0.00481 -0.26 -0.2583 -1.0 1911694 Bionet2_000859 FC(F)(F)c1ccccc1/C=C/2\N3CCC(CC3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H02 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1505872 Bionet2_000860 C=CCNC(=O)c1ccccc1Sc2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H03 compound treatment 0.429 0.185 9.95 9.9519 1.0 1911695 Bionet2_000861 CCOC(=O)CN1CCC(CC1)c2cc([nH]n2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H04 compound treatment 0.252 0.00819 0.44 0.4403 1.0 1911696 Bionet2_000862 Cc1noc(C)c1Cc2c(Cl)cccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H05 compound treatment 0.296 0.0522 2.8 2.8048 1.0 1911697 Bionet2_000863 Fc1cccc(n1)N2CCC(=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H06 compound treatment 0.321 0.0772 4.15 4.1482 1.0 1911698 Bionet2_000864 C1Cc2cnc(nc2-c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H07 compound treatment 0.298 0.0542 2.91 2.9122 1.0 1911699 Bionet2_000865 Oc1ccc(cc1)c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H08 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1911700 Bionet2_000866 Cc1nc(O)cc(CSc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H09 compound treatment 0.381 0.137 7.37 7.3725 1.0 1911701 Bionet2_000867 Fc1ccc(cc1)c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H10 compound treatment 0.497 0.253 13.61 13.6061 1.0 1911702 Bionet2_000868 c1cc(n[nH]1)c2cnc(s2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H11 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1023418 Bionet2_000869 CC(=C)C(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H12 compound treatment 0.246 0.00219 0.12 0.1179 1.0 1911703 Bionet2_000870 COc1ccc(cc1)/C(=C/C(=O)O)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H13 compound treatment 0.356 0.112 6.03 6.029 1.0 1911704 Bionet2_000871 CC(C)c1ccc(cc1)N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H14 compound treatment 0.407 0.163 8.77 8.7697 1.0 1911705 Bionet2_000872 CC1=C(C#N)/C(=C/Nc2cccc(Cl)c2)/CC(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H15 compound treatment 0.245 0.00119 0.06 0.0641 1.0 1911706 Bionet2_000873 CC1(C)CN(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H16 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1521571 Bionet2_000874 COc1cc(N2C(=O)CSCC2=O)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H17 compound treatment 0.264 0.0202 1.09 1.0852 1.0 1442634 Bionet2_000875 Clc1ccc(Nc2nnnc3ccccc23)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H18 compound treatment 0.231 -0.0128 -0.69 -0.6882 -1.0 1911707 Bionet2_000876 CN(C)c1ccnc(Nc2ccccc2C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H19 compound treatment 0.247 0.00319 0.17 0.1716 1.0 1911708 Bionet2_000877 Cc1ccc(CNC(=O)c2ccccc2NC(=O)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H20 compound treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1911709 Bionet2_000878 OC(=O)c1ccccc1c2nnc3c(Cl)cc(cn23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H21 compound treatment 0.266 0.0222 1.19 1.1926 1.0 1911710 Bionet2_000879 FC(F)(F)c1ccc(COC(=O)N/C=C/c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H22 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1684058 Bionet2_000880 CCOC(=O)c1cc(C#N)c(Cl)nc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H23 mock treatment 0.246 0.00219 0.12 0.1179 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 H24 mock treatment 0.231 -0.0128 -0.69 -0.6882 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I01 compound treatment 0.222 -0.0218 -1.17 -1.1718 -1.0 1911711 Bionet2_000881 Cc1occc(=O)c1Oc2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I02 compound treatment 0.254 0.0102 0.55 0.5478 1.0 1911712 Bionet2_000882 CCCC(=O)Nc1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I03 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1911713 Bionet2_000883 Oc1cc(cnc1S(=O)(=O)c2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I04 compound treatment 0.235 -0.00881 -0.47 -0.4732 -1.0 1911714 Bionet2_000884 Oc1cc(O)c(c(Cl)n1)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I05 compound treatment 0.43 0.186 10.01 10.0057 1.0 1190239 Bionet2_000885 O=c1[nH]cc(cc1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I06 compound treatment 0.231 -0.0128 -0.69 -0.6882 -1.0 1911715 Bionet2_000886 c1cn(cn1)c2ccccc2c3nc[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I07 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1911716 Bionet2_000887 N/C(=N\O)/c1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I08 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911717 Bionet2_000888 Cc1nn(c(C)c1CS(=O)(=O)c2ccccc2)c3ncc(cc3Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I09 compound treatment 0.385 0.141 7.59 7.5874 1.0 1911718 Bionet2_000889 COc1ccc(cc1)N2C(/C=N/O)C(=CC2=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I10 compound treatment 0.227 -0.0168 -0.9 -0.9031 -1.0 1582835 Bionet2_000890 CNC1C(CO)COc2ccc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I11 compound treatment 0.256 0.0122 0.66 0.6553 1.0 1911719 Bionet2_000891 FC(F)(F)c1cnc(c(Cl)c1)n2cccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I12 compound treatment 0.331 0.0872 4.69 4.6856 1.0 1491815 Bionet2_000892 C1COC(O1)c2ccc3noc(c4ccccc4)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I13 compound treatment 0.291 0.0472 2.54 2.5361 1.0 1911720 Bionet2_000893 N#CC(c1ccccc1)c2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I14 compound treatment 0.271 0.0272 1.46 1.4613 1.0 1038902 Bionet2_000894 Clc1ccc(NS(=O)(=O)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I15 compound treatment 0.469 0.225 12.1 12.1014 1.0 1242935 Bionet2_000895 COc1ccc(cc1)C(C#N)c2ccc(cc2)C(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I16 compound treatment 0.358 0.114 6.14 6.1365 1.0 1911721 Bionet2_000896 Cc1ccc(cc1)C(CC(=O)c2ccc(Cl)cc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I17 compound treatment 0.264 0.0202 1.09 1.0852 1.0 1533565 Bionet2_000897 COC(=O)C1=C(N)c2c(cccc2F)C1(C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I18 compound treatment 0.294 0.0502 2.7 2.6973 1.0 1911722 Bionet2_000898 Cc1[nH]c2ccccc2c1c3ncc(cc3Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I19 compound treatment 0.457 0.213 11.46 11.4566 1.0 1911723 Bionet2_000899 c1ccn(c1)c2nc3nccc(c4ccco4)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I20 compound treatment 0.459 0.215 11.56 11.5641 1.0 1250775 Bionet2_000900 O=C(c1cccs1)c2ccc(CC#N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I21 compound treatment 0.241 -0.00281 -0.15 -0.1508 -1.0 1911724 Bionet2_000901 Nc1ncc(cn1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I22 compound treatment 0.422 0.178 9.58 9.5757 1.0 1498829 Bionet2_000902 O=C(CC(=O)Nc1cccnc1)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I23 mock treatment 0.248 0.00419 0.23 0.2254 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 I24 mock treatment 0.25 0.00619 0.33 0.3328 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J01 compound treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1911725 Bionet2_000903 FC(F)(F)c1cnc(c(Cl)c1)c2cnc(nc2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J02 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1911726 Bionet2_000904 CSCc1cc(O)nc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J03 compound treatment 0.257 0.0132 0.71 0.709 1.0 1911727 Bionet2_000905 OCc1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J04 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1080279 Bionet2_000906 COC(=O)C1CN(Cc2ccccc2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J05 compound treatment 0.299 0.0552 2.97 2.966 1.0 1911728 Bionet2_000907 Cc1nnc(nc1O)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J06 compound treatment 0.252 0.00819 0.44 0.4403 1.0 1911729 Bionet2_000908 COCc1cc(O)nc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J07 compound treatment 0.279 0.0352 1.89 1.8912 1.0 1911730 Bionet2_000909 COC(=O)c1sc(nc1C)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J08 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1911731 Bionet2_000910 FC(F)(F)C(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J09 compound treatment 0.344 0.1 5.38 5.3842 1.0 1911732 Bionet2_000911 FC(F)(F)c1cccc(c1)c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J10 compound treatment 0.241 -0.00281 -0.15 -0.1508 -1.0 1222057 Bionet2_000912 CN1CCN(CC1)c2cc(Cl)nc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J11 compound treatment 0.266 0.0222 1.19 1.1926 1.0 1489823 Bionet2_000913 CC1(C)CN(C1=O)c2cccc(C#N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J12 compound treatment 0.278 0.0342 1.84 1.8375 1.0 1060540 Bionet2_000914 O=C1Cc2ccccc2C(=O)N1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J13 compound treatment 0.239 -0.00481 -0.26 -0.2583 -1.0 1296266 Bionet2_000915 CC1(C)CN(C1=O)c2cccc(n2)N3CC(C)(C)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J14 compound treatment 0.261 0.0172 0.92 0.9239 1.0 1911733 Bionet2_000916 Nc1nccc(n1)c2ccc(Sc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J15 compound treatment 0.455 0.211 11.35 11.3491 1.0 1371849 Bionet2_000917 CC1(C)CN(C1=O)c2ccc(OCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J16 compound treatment 0.242 -0.00181 -0.1 -0.0971 -1.0 1911734 Bionet2_000918 COc1ccnc(N)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J17 compound treatment 0.297 0.0532 2.86 2.8585 1.0 1618635 Bionet2_000919 CCN(CC)c1cc(CS(=O)c2ccccc2)nc(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J18 compound treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1911735 Bionet2_000920 Cc1cccc(C)c1N2C(=O)CSC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J19 compound treatment 0.319 0.0752 4.04 4.0407 1.0 1911736 Bionet2_000921 Clc1ccsc1c2ccn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J20 compound treatment 0.448 0.204 10.97 10.9729 1.0 1911737 Bionet2_000922 Clc1ccc(Sc2cnccc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J21 compound treatment 0.261 0.0172 0.92 0.9239 1.0 1911738 Bionet2_000923 COC(=O)CN1C(=O)Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J22 compound treatment 0.269 0.0252 1.35 1.3538 1.0 1911739 Bionet2_000924 CC(C)/N=C/c1nc([nH]c1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J23 mock treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 J24 mock treatment 0.245 0.00119 0.06 0.0641 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K01 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1911740 Bionet2_000925 Cc1[nH]ccc(=O)c1Oc2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K02 compound treatment 0.284 0.0402 2.16 2.1599 1.0 1670843 Bionet2_000926 Cc1c(oc2ccccc12)C(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K03 compound treatment 0.298 0.0542 2.91 2.9122 1.0 1911741 Bionet2_000927 O/N=C/c1cc(Br)ccc1OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K04 compound treatment 0.278 0.0342 1.84 1.8375 1.0 1911742 Bionet2_000928 Clc1ncccc1c2nc3ccccc3n2Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K05 compound treatment 0.26 0.0162 0.87 0.8702 1.0 1911743 Bionet2_000929 COc1ccc(CC(C#N)C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K06 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911744 Bionet2_000930 Cc1nc(c(s1)c2ncn(n2)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K07 compound treatment 0.285 0.0412 2.21 2.2137 1.0 1911745 Bionet2_000931 CC(Sc1ncc(cc1Cl)C(F)(F)F)c2ccn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K08 compound treatment 0.236 -0.00781 -0.42 -0.4195 -1.0 1911746 Bionet2_000932 Cc1n[nH]c(C)c1CS(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K09 compound treatment 0.279 0.0352 1.89 1.8912 1.0 1124326 Bionet2_000933 Nc1[nH]ncc1c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K10 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1911747 Bionet2_000934 Cc1nc(C)c(C#N)c(c1C#N)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K11 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1911748 Bionet2_000935 OCc1cccn1c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K12 compound treatment 0.265 0.0212 1.14 1.1389 1.0 1285310 Bionet2_000936 OC(=O)Cc1sc(nc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K13 compound treatment 0.268 0.0242 1.3 1.3001 1.0 1911749 Bionet2_000937 Cn1cccc1C(C#N)c2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K14 compound treatment 0.281 0.0372 2.0 1.9987 1.0 1723181 Bionet2_000938 CCOC(=O)NC1Cc2ccccc2C1Sc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K15 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1431055 Bionet2_000939 COC(=O)CC(C#N)(c1ccccc1)c2cccc(F)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K16 compound treatment 0.443 0.199 10.7 10.7042 1.0 1627015 Bionet2_000940 COc1cccc(c1)C(=O)CC(C#N)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K17 compound treatment 0.288 0.0442 2.37 2.3749 1.0 1911750 Bionet2_000941 COC(=O)/C=C/C1=C(N)c2ccccc2C1(C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K18 compound treatment 0.253 0.00919 0.49 0.494 1.0 1257165 Bionet2_000942 CC1(C)CC(=C(CS(=O)(=O)c2ccccc2)C(=O)C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K19 compound treatment 0.416 0.172 9.25 9.2533 1.0 1911751 Bionet2_000943 c1ccn(c1)c2nc3nccc(c4ccccn4)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K20 compound treatment 0.513 0.269 14.47 14.4659 1.0 1736358 Bionet2_000944 O=C(c1ccco1)c2ccc(CC#N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K21 compound treatment 0.276 0.0322 1.73 1.73 1.0 1911752 Bionet2_000945 NC(=O)c1ccc(nc1O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K22 compound treatment 0.327 0.0832 4.47 4.4706 1.0 1433620 Bionet2_000946 COC(=O)CC(=O)N1CCN(CC1)c2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K23 mock treatment 0.258 0.0142 0.76 0.7627 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 K24 mock treatment 0.251 0.00719 0.39 0.3866 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L01 compound treatment 0.343 0.0992 5.33 5.3305 1.0 1383067 Bionet2_000947 Clc1ccc(cc1)c2cc(n[nH]2)C3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L02 compound treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1125030 Bionet2_000948 COc1ccc(cc1OC)C(=O)c2c[nH]cc2c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L03 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1073609 Bionet2_000949 BrCC1(OCCO1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L04 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1911753 Bionet2_000950 CN(C)c1cc(Cl)nc(N(C)C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L05 compound treatment 0.474 0.23 12.37 12.3701 1.0 1911754 Bionet2_000951 Clc1ccc(c2nc(no2)c3ccccn3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L06 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1911755 Bionet2_000952 COCc1cc(Cl)nc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L07 compound treatment 0.477 0.233 12.53 12.5313 1.0 1911756 Bionet2_000953 Clc1ccc(cc1Cl)c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L08 compound treatment 0.252 0.00819 0.44 0.4403 1.0 1911757 Bionet2_000954 Cc1cc(nc(n1)c2ccccc2)C(F)(F)Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L09 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1392951 Bionet2_000955 OC(=O)CSC1CCC(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L10 compound treatment 0.309 0.0652 3.5 3.5034 1.0 1911758 Bionet2_000956 CCCN(CCC)c1cc(Cl)nc(SC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L11 compound treatment 0.289 0.0452 2.43 2.4286 1.0 1575301 Bionet2_000957 CC1(C)CN(C1=O)c2ccc(cc2)N3CC(C)(C)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L12 compound treatment 0.253 0.00919 0.49 0.494 1.0 1199862 Bionet2_000958 O=C1N(Cc2ccccc2)C(=O)C3(CCCC3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L13 compound treatment 0.258 0.0142 0.76 0.7627 1.0 1911759 Bionet2_000959 COc1ccc(cc1)N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L14 compound treatment 0.445 0.201 10.81 10.8117 1.0 1235232 Bionet2_000960 Cn1ccc(n1)c2ccc(Oc3cccc(Cl)c3C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L15 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1242376 Bionet2_000961 COC(=O)c1cc(cc(c1)N2CC(C)(C)C2=O)N3CC(C)(C)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L16 compound treatment 0.27 0.0262 1.41 1.4076 1.0 1911760 Bionet2_000962 COc1ccnc(Oc2cccc(c2)C(F)(F)F)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L17 compound treatment 0.271 0.0272 1.46 1.4613 1.0 1911761 Bionet2_000963 CNc1cc(CS(=O)c2ccccc2)nc(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L18 compound treatment 0.265 0.0212 1.14 1.1389 1.0 1911762 Bionet2_000964 COc1c(C#N)sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L19 compound treatment 0.435 0.191 10.27 10.2743 1.0 1911763 Bionet2_000965 Clc1ccsc1c2ccnn2C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L20 compound treatment 0.254 0.0102 0.55 0.5478 1.0 1505185 Bionet2_000966 COc1ccc(CCN2C(=O)C3C4CC(C=C4)C3C2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L21 compound treatment 0.236 -0.00781 -0.42 -0.4195 -1.0 1911764 Bionet2_000967 CN(C)c1n[nH]c(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L22 compound treatment 0.274 0.0302 1.62 1.6225 1.0 1534273 Bionet2_000968 C1CN(CCO1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L23 mock treatment 0.242 -0.00181 -0.1 -0.0971 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 L24 mock treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M01 compound treatment 0.239 -0.00481 -0.26 -0.2583 -1.0 1390509 Bionet2_000969 Cc1[nH]ccc(=O)c1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M02 compound treatment 0.248 0.00419 0.23 0.2254 1.0 1448217 Bionet2_000970 COC(=O)c1c(C(=O)OC)c2CCCn2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M03 compound treatment 0.241 -0.00281 -0.15 -0.1508 -1.0 1235182 Bionet2_000971 CN1CCN(CC(O)(c2ccc(F)cc2)c3ccc(F)cc3)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M04 compound treatment 0.248 0.00419 0.23 0.2254 1.0 1014042 Bionet2_000972 ClCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M05 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1286758 Bionet2_000973 Cc1nc(N)c(Cc2ccc(Cl)cc2Cl)c(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M06 compound treatment 0.291 0.0472 2.54 2.5361 1.0 1911765 Bionet2_000974 OC(CSc1ccc(F)cc1)CN2CCN(CC2)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M07 compound treatment 0.33 0.0862 4.63 4.6319 1.0 1349252 Bionet2_000975 CC(O)(CS(=O)(=O)Cc1ccc(Cl)cc1)C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M08 compound treatment 0.249 0.00519 0.28 0.2791 1.0 1911766 Bionet2_000976 CC(=O)n1nc(C)c(CS(=O)(=O)c2ccccc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M09 compound treatment 0.254 0.0102 0.55 0.5478 1.0 1911767 Bionet2_000977 FC(F)(F)c1n[nH]cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M10 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1911768 Bionet2_000978 Cc1nc(C)c(C#N)c(c1C#N)c2c(Cl)cccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M11 compound treatment 0.243 -8.06E-4 -0.04 -0.0433 -1.0 1911769 Bionet2_000979 CCOC(=O)c1cccn1c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M12 compound treatment 0.28 0.0362 1.94 1.945 1.0 1911770 Bionet2_000980 FC(F)(F)c1cnc(C#N)c(SCc2ccc(Cl)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M13 compound treatment 0.272 0.0282 1.52 1.5151 1.0 1158948 Bionet2_000981 O=C(c1ccccc1)c2ccccc2C(C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M14 compound treatment 0.262 0.0182 0.98 0.9777 1.0 1911771 Bionet2_000982 CCOC(=O)CSc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M15 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911772 Bionet2_000983 Cc1nn(C)c(Oc2cccc(c2)C(F)(F)F)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M16 compound treatment 0.249 0.00519 0.28 0.2791 1.0 1322697 Bionet2_000984 COc1cccc(c1)C(=O)CC(C(=O)O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M17 compound treatment 0.258 0.0142 0.76 0.7627 1.0 1423906 Bionet2_000985 COc1cccc(c1)n2c(C)cc3C(=O)CC(C)(C)Cc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M18 compound treatment 0.252 0.00819 0.44 0.4403 1.0 1911773 Bionet2_000986 OC(=O)Cc1cn(c2ncc(cc2Cl)C(F)(F)F)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M19 compound treatment 0.454 0.21 11.3 11.2954 1.0 1911774 Bionet2_000987 c1ccn(c1)c2nc3nccc(c4cccs4)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M20 compound treatment 0.237 -0.00681 -0.37 -0.3658 -1.0 1226861 Bionet2_000988 CC(N1Cc2ccccc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M21 compound treatment 0.25 0.00619 0.33 0.3328 1.0 1911775 Bionet2_000989 CC(C)NC(=O)c1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M22 compound treatment 0.258 0.0142 0.76 0.7627 1.0 1911776 Bionet2_000990 Cc1onc(C(=O)N)c1C(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M23 mock treatment 0.236 -0.00781 -0.42 -0.4195 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 M24 mock treatment 0.238 -0.00581 -0.31 -0.312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N01 compound treatment 0.265 0.0212 1.14 1.1389 1.0 1911777 Bionet2_000991 COc1ccc(/C=C\2/N3CCC(CC3)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N02 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1911778 Bionet2_000992 CS(=O)Cc1cc(Cl)nc(n1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N03 compound treatment 0.264 0.0202 1.09 1.0852 1.0 1353267 Bionet2_000993 COc1ccc(NC(=O)c2cccnc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N04 compound treatment 0.236 -0.00781 -0.42 -0.4195 -1.0 1911779 Bionet2_000994 OC(=O)CNC(=O)c1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N05 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1911780 Bionet2_000995 OC(=O)c1cnn(c2nc(cs2)c3ccccc3)c1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N06 compound treatment 0.312 0.0682 3.66 3.6646 1.0 1911781 Bionet2_000996 COc1ccc(COC(=O)N/C=C/c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N07 compound treatment 0.393 0.149 8.02 8.0173 1.0 1911782 Bionet2_000997 Brc1ccc(cc1)c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N08 compound treatment 0.247 0.00319 0.17 0.1716 1.0 1911783 Bionet2_000998 O/N=C/c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N09 compound treatment 0.252 0.00819 0.44 0.4403 1.0 1410660 Bionet2_000999 OC(=O)c1ccccc1SC2CCC(=O)N2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N10 compound treatment 0.286 0.0422 2.27 2.2674 1.0 1911784 Bionet2_001000 CCNc1cc(Cl)nc(SC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N11 compound treatment 0.441 0.197 10.6 10.5968 1.0 1911785 Bionet2_001001 CCOC(=O)c1ccc(cc1)N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N12 compound treatment 0.3 0.0562 3.02 3.0197 1.0 1911786 Bionet2_001002 Cc1nn(nc1C(=O)O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N13 compound treatment 0.373 0.129 6.94 6.9426 1.0 1911787 Bionet2_001003 CC1(C)CN(C1=O)c2ccc(cc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N14 compound treatment 0.233 -0.0108 -0.58 -0.5807 -1.0 1911788 Bionet2_001004 CCSC1=NC(=CC(C)(C)N1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N15 compound treatment 0.256 0.0122 0.66 0.6553 1.0 1911789 Bionet2_001005 CC1(C)CN(C1=O)c2ccc(CC#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N16 compound treatment 0.268 0.0242 1.3 1.3001 1.0 1911790 Bionet2_001006 Fc1ccc(/N=C/2\C(=O)N(c3ccccc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N17 compound treatment 0.425 0.181 9.74 9.737 1.0 1911791 Bionet2_001007 Oc1n[n+](cc2ccccc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N18 compound treatment 0.233 -0.0108 -0.58 -0.5807 -1.0 1911792 Bionet2_001008 Cc1nnsc1C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N19 compound treatment 0.249 0.00519 0.28 0.2791 1.0 1911793 Bionet2_001009 FC(F)(F)S(=O)(=O)n1nccc1c2sccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N20 compound treatment 0.264 0.0202 1.09 1.0852 1.0 1911794 Bionet2_001010 OC(CNc1ncc(cc1Cl)C(F)(F)F)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N21 compound treatment 0.314 0.0702 3.77 3.7721 1.0 1361149 Bionet2_001011 CC1=C(C#N)C(C(=C(C)N1)C#N)c2sc3ccccc3c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N22 compound treatment 0.254 0.0102 0.55 0.5478 1.0 1911795 Bionet2_001012 Cn1nc(c(/C=N/O)c1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N23 mock treatment 0.236 -0.00781 -0.42 -0.4195 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 N24 mock treatment 0.229 -0.0148 -0.8 -0.7957 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O01 compound treatment 0.393 0.149 8.02 8.0173 1.0 1424041 Bionet2_001013 Cc1cc2n(Cc3ccccc3)cnc2c(N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O02 compound treatment 0.314 0.0702 3.77 3.7721 1.0 1911796 Bionet2_001014 Cc1cc2nc([nH]c2cc1C)c3ccc(Cl)nc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O03 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1252144 Bionet2_001015 OC(CN1CCOCC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O04 compound treatment 0.316 0.0722 3.88 3.8795 1.0 1911797 Bionet2_001016 Cc1ccc(SCc2nc3ccccc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O05 compound treatment 0.261 0.0172 0.92 0.9239 1.0 1911798 Bionet2_001017 Fc1ccccc1CC(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O06 compound treatment 0.231 -0.0128 -0.69 -0.6882 -1.0 1911799 Bionet2_001018 COC(=O)c1sccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O07 compound treatment 0.226 -0.0178 -0.96 -0.9569 -1.0 1911800 Bionet2_001019 NC(=O)c1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O08 compound treatment 0.245 0.00119 0.06 0.0641 1.0 1911801 Bionet2_001020 Cc1nn(C)c(C)c1CS(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O09 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1911802 Bionet2_001021 FC(F)(F)c1cnc(c2cnoc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O10 compound treatment 0.244 1.94E-4 0.01 0.0104 1.0 1911803 Bionet2_001022 C/C(=C(\C#N)/C(=O)N)/NCc1ccncc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O11 compound treatment 0.257 0.0132 0.71 0.709 1.0 1911804 Bionet2_001023 OC(=O)c1cccn1c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O12 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1911805 Bionet2_001024 FC(F)(F)c1cnc(C#N)c(c1)S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O13 compound treatment 0.382 0.138 7.43 7.4262 1.0 1682930 Bionet2_001025 O=C(c1ccccc1)c2ccc(cc2)C(C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O14 compound treatment 0.26 0.0162 0.87 0.8702 1.0 1911806 Bionet2_001026 OC(=O)CSc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O15 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1911807 Bionet2_001027 Cc1nn(C)c(Oc2cccc(Cl)c2)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O16 compound treatment 0.33 0.0862 4.63 4.6319 1.0 1128888 Bionet2_001028 COC(=O)C(CC(=O)c1cccc(C)c1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O17 compound treatment 0.408 0.164 8.82 8.8234 1.0 1911808 Bionet2_001029 CN(O)/C=C/1\C(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O18 compound treatment 0.393 0.149 8.02 8.0173 1.0 1911809 Bionet2_001030 COC(=O)Cc1cn(c2ncc(cc2Cl)C(F)(F)F)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O19 compound treatment 0.519 0.275 14.79 14.7883 1.0 1658567 Bionet2_001031 Cc1ccc(SCC(=O)c2cc(C)c(O)c(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O20 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1210349 Bionet2_001032 OC(=O)C(Cc1ccccc1)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O21 compound treatment 0.263 0.0192 1.03 1.0314 1.0 1911810 Bionet2_001033 CO/C=C(/Oc1ccc(Cl)cc1Br)\C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O22 compound treatment 0.259 0.0152 0.82 0.8165 1.0 1267841 Bionet2_001034 Cc1ccc(NC(=O)CC(=O)Nc2ccc(C)cc2C)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O23 mock treatment 0.265 0.0212 1.14 1.1389 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 O24 mock treatment 0.24 -0.00381 -0.2 -0.2046 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P01 compound treatment 0.252 0.00819 0.44 0.4403 1.0 1727230 Bionet2_001035 CCOC(=O)c1cnc2ccc(Cl)cc2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P02 compound treatment 0.23 -0.0138 -0.74 -0.7419 -1.0 1911811 Bionet2_001036 CC(C)(C)NC(=O)CCc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P03 compound treatment 0.239 -0.00481 -0.26 -0.2583 -1.0 1911812 Bionet2_001037 O=C1CC(CC(=O)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P04 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1529198 Bionet2_001038 Fc1cccc(n1)N2CCc3c(C#N)c(sc3C2)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P05 compound treatment 0.222 -0.0218 -1.17 -1.1718 -1.0 1911813 Bionet2_001039 Cc1ccc(CS(=O)(=O)c2ccccc2c3nnc(o3)c4ccc(Cl)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P06 compound treatment 0.295 0.0512 2.75 2.751 1.0 1911814 Bionet2_001040 Clc1ccc(COC(=O)N/C=C/c2ccccc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P07 compound treatment 0.39 0.146 7.86 7.8561 1.0 1911815 Bionet2_001041 Clc1ccc(cc1)c2csnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P08 compound treatment 0.248 0.00419 0.23 0.2254 1.0 1671170 Bionet2_001042 O=C(N1CCOCC1)c2[nH]c3ccccc3c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P09 compound treatment 0.247 0.00319 0.17 0.1716 1.0 1911816 Bionet2_001043 FC(F)(F)c1ccc2n(CCNc3ncc(cc3Cl)C(F)(F)F)c(=O)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P10 compound treatment 0.223 -0.0208 -1.12 -1.1181 -1.0 1118600 Bionet2_001044 CC(C)Oc1cc(N)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P11 compound treatment 0.255 0.0112 0.6 0.6015 1.0 1911817 Bionet2_001045 CC1(C)CN(C1=O)c2ccc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P12 compound treatment 0.439 0.195 10.49 10.4893 1.0 1911818 Bionet2_001046 CCOC(=O)c1cc(nnc1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P13 compound treatment 0.266 0.0222 1.19 1.1926 1.0 1537859 Bionet2_001047 COC(=O)c1sccc1N2CC(C)(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P14 compound treatment 0.263 0.0192 1.03 1.0314 1.0 1423514 Bionet2_001048 CCOC(=O)C1=C(C)NC(=O)CC1c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P15 compound treatment 0.232 -0.0118 -0.63 -0.6345 -1.0 1911819 Bionet2_001049 CC1(C)CN(C1=O)c2ccc(Br)cc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P16 compound treatment 0.279 0.0352 1.89 1.8912 1.0 1911820 Bionet2_001050 COc1ccc(/N=C/2\C(=O)N(c3ccccc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P17 compound treatment 0.261 0.0172 0.92 0.9239 1.0 1911821 Bionet2_001051 COc1ccc(cc1)C(C#N)c2nc3ccccc3nc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P18 compound treatment 0.339 0.0952 5.12 5.1155 1.0 1911822 Bionet2_001052 Nc1nnc(SCc2ccc(Cl)c(Cl)c2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P19 compound treatment 0.397 0.153 8.23 8.2323 1.0 1313555 Bionet2_001053 Brc1ccsc1c2csc(n2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P20 compound treatment 0.481 0.237 12.75 12.7463 1.0 1911823 Bionet2_001054 O=C(/C=C/c1ccco1)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P21 compound treatment 0.251 0.00719 0.39 0.3866 1.0 1163514 Bionet2_001055 Cc1cc(C)n(n1)c2ccnc3cc(Cl)ccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P22 compound treatment 0.319 0.0752 4.04 4.0407 1.0 1187455 Bionet2_001056 COc1ccc(Cn2c(=O)sc3ccccc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P23 mock treatment 0.229 -0.0148 -0.8 -0.7957 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1366 P24 mock treatment 0.245 0.00119 0.06 0.0641 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A01 compound treatment 0.221 -0.0331 -1.78 -1.7784 -1.0 1911824 Bionet2_001057 Fc1ccc(CNC(=O)/C(=C/c2cccs2)/c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A02 compound treatment 0.241 -0.0131 -0.7 -0.7036 -1.0 1466754 Bionet2_001058 Clc1ccc(cc1)c2nc3ccc(cc3c(=O)[nH]2)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A03 compound treatment 0.285 0.0309 1.66 1.6608 1.0 1911825 Bionet2_001059 O[C@H](CSc1nc2ccccc2o1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A04 compound treatment 0.241 -0.0131 -0.7 -0.7036 -1.0 1911826 Bionet2_001060 FC(F)(F)c1cnc(CC(=O)NCC2CCCO2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A05 compound treatment 0.261 0.00691 0.37 0.3711 1.0 1911827 Bionet2_001061 Cc1ccsc1/C=C/C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A06 compound treatment 0.281 0.0269 1.45 1.4459 1.0 1911828 Bionet2_001062 Nc1[nH]ncc1S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A07 compound treatment 0.236 -0.0181 -0.97 -0.9723 -1.0 1911829 Bionet2_001063 CC1=NCCN1S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A08 compound treatment 0.5 0.246 13.21 13.2145 1.0 1525087 Bionet2_001064 O=C(Cc1ccccc1)c2c[nH]c(c2)C(=O)NCCc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A09 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1911830 Bionet2_001065 FC(F)(F)c1cccc(CNC(=O)c2ccc[nH]2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A10 compound treatment 0.243 -0.0111 -0.6 -0.5962 -1.0 1911831 Bionet2_001066 COc1ccc(cc1)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A11 compound treatment 0.244 -0.0101 -0.54 -0.5424 -1.0 1601613 Bionet2_001067 COc1ccc(cc1)C(CC(=O)O)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A12 compound treatment 0.41 0.156 8.38 8.3781 1.0 1911832 Bionet2_001068 O=C(NCCCn1ccnc1)c2cc(c[nH]2)C(=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A13 compound treatment 0.223 -0.0311 -1.67 -1.6709 -1.0 1274106 Bionet2_001069 Oc1nc(c2ccccc2)c3CCCCc3c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A14 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1911833 Bionet2_001070 Nc1nccc(n1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A15 compound treatment 0.496 0.242 13.0 12.9995 1.0 1296309 Bionet2_001071 CC(C)N(C(C)C)C(=O)c1cc(c[nH]1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A16 compound treatment 0.267 0.0129 0.69 0.6936 1.0 1911834 Bionet2_001072 CC(O)c1ccc(cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A17 compound treatment 0.293 0.0389 2.09 2.0907 1.0 1289337 Bionet2_001073 O=C(NCc1ccccc1)c2cc(c[nH]2)C(=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A18 compound treatment 0.529 0.275 14.77 14.7729 1.0 1911835 Bionet2_001074 c1cc([nH]n1)c2cc3c(ccc4ccccc34)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A19 compound treatment 0.265 0.0109 0.59 0.5861 1.0 1729737 Bionet2_001075 COC(=O)c1sccc1NC(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A20 compound treatment 0.264 0.00991 0.53 0.5323 1.0 1911836 Bionet2_001076 NC(CC(=O)O)C1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A21 compound treatment 0.271 0.0169 0.91 0.9085 1.0 1327894 Bionet2_001077 OC(=O)C1CN(CCc2c[nH]c3ccccc23)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A22 compound treatment 0.288 0.0339 1.82 1.8221 1.0 1911837 Bionet2_001078 Clc1ccc(cc1Cl)C(=O)n2ccc(n2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A23 mock treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 A24 mock treatment 0.263 0.00891 0.48 0.4786 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B01 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1911838 Bionet2_001079 Cn1cc(C(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B02 compound treatment 0.273 0.0189 1.02 1.016 1.0 1911839 Bionet2_001080 CCOc1ncccc1C(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B03 compound treatment 0.261 0.00691 0.37 0.3711 1.0 1911840 Bionet2_001081 CC(C)C(CC(=O)O)N1Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B04 compound treatment 0.256 0.00191 0.1 0.1024 1.0 1911841 Bionet2_001082 Cc1ccc(C)n1C(CC(=O)O)c2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B05 compound treatment 0.247 -0.00709 -0.38 -0.3812 -1.0 1911842 Bionet2_001083 Cc1ccc(C)n1NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B06 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1911843 Bionet2_001084 OC(=O)CCC(=O)c1ccc2CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B07 compound treatment 0.361 0.107 5.74 5.7449 1.0 1911844 Bionet2_001085 O=C1COc2ccc(cc2N1)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B08 compound treatment 0.41 0.156 8.38 8.3781 1.0 1911845 Bionet2_001086 Clc1ccc(cc1)C2=COc3ccccc3C(=O)N2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B09 compound treatment 0.464 0.21 11.28 11.2799 1.0 1911846 Bionet2_001087 Clc1cccc(CCC(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B10 compound treatment 0.306 0.0519 2.79 2.7893 1.0 1154192 Bionet2_001088 OC(=O)c1oc2ccccc2c1n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B11 compound treatment 0.29 0.0359 1.93 1.9295 1.0 1911847 Bionet2_001089 c1ccc(cc1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B12 compound treatment 0.278 0.0239 1.28 1.2847 1.0 1911848 Bionet2_001090 CC(C)(C)n1cc(cn1)C(=O)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B13 compound treatment 0.29 0.0359 1.93 1.9295 1.0 1911849 Bionet2_001091 C(N1CCc2nc3ccccc3cc2C1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B14 compound treatment 0.287 0.0329 1.77 1.7683 1.0 1009047 Bionet2_001092 COc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B15 compound treatment 0.344 0.0899 4.83 4.8314 1.0 1911850 Bionet2_001093 COC(=O)COc1ccccc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B16 compound treatment 0.272 0.0179 0.96 0.9622 1.0 1392954 Bionet2_001094 COc1cccc(NC(=O)Cc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B17 compound treatment 0.285 0.0309 1.66 1.6608 1.0 1911851 Bionet2_001095 CN1C(=O)S/C(=C/c2cccnc2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B18 compound treatment 0.385 0.131 7.03 7.0346 1.0 1911852 Bionet2_001096 COc1ccc-2c(CCc3cn4ncc(C#N)c4nc32)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B19 compound treatment 0.264 0.00991 0.53 0.5323 1.0 1911853 Bionet2_001097 CN1CCN(CC1)c2nc(C)c(Br)c(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B20 compound treatment 0.241 -0.0131 -0.7 -0.7036 -1.0 1911854 Bionet2_001098 OCc1cc(Cl)ncc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B21 compound treatment 0.263 0.00891 0.48 0.4786 1.0 1911855 Bionet2_001099 Cc1ccccc1C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B22 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1911856 Bionet2_001100 OC(=O)Cc1ccc2ocnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B23 mock treatment 0.259 0.00491 0.26 0.2637 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 B24 mock treatment 0.244 -0.0101 -0.54 -0.5424 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C01 compound treatment 0.272 0.0179 0.96 0.9622 1.0 1658013 Bionet2_001101 CCC(=O)c1c[nH]c(c1)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C02 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1401216 Bionet2_001102 COC(=O)CC(N)c1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C03 compound treatment 0.25 -0.00409 -0.22 -0.22 -1.0 1911857 Bionet2_001103 Cn1cc(C(O)C(F)(F)F)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C04 compound treatment 0.248 -0.00609 -0.33 -0.3275 -1.0 1911858 Bionet2_001104 FC(F)(F)c1cnc(CC(=O)NC2CCCC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C05 compound treatment 0.265 0.0109 0.59 0.5861 1.0 1911859 Bionet2_001105 Cc1cc2nccc(c3ccccc3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C06 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1471443 Bionet2_001106 COc1cc2CCC=Nc2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C07 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1283880 Bionet2_001107 CCC(CC)C(=O)c1c[nH]c(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C08 compound treatment 0.417 0.163 8.75 8.7542 1.0 1911860 Bionet2_001108 COc1ccc(C/N=C/2\SCC(=O)N2c3ccccc3)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C09 compound treatment 0.272 0.0179 0.96 0.9622 1.0 1615048 Bionet2_001109 Clc1ccccc1CNC(=O)c2ccc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C10 compound treatment 0.269 0.0149 0.8 0.801 1.0 1911861 Bionet2_001110 Nc1[nH]ncc1c2ccsc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C11 compound treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1911862 Bionet2_001111 COC(=O)[C@@H]1CC(=C(C)C[C@H]1C(=O)OC)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C12 compound treatment 0.548 0.294 15.79 15.7939 1.0 1197696 Bionet2_001112 O=C(NCCc1ccccn1)c2cc(c[nH]2)C(=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C13 compound treatment 0.365 0.111 5.96 5.9599 1.0 1669134 Bionet2_001113 O=C(NCc1ccncc1)c2cc(c[nH]2)C(=O)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C14 compound treatment 0.312 0.0579 3.11 3.1118 1.0 1632097 Bionet2_001114 COc1ccc(cc1)c2c[nH]nc2c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C15 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1719844 Bionet2_001115 CC(C)CC(N1Cc2ccccc2C1=O)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C16 compound treatment 0.292 0.0379 2.04 2.037 1.0 1911863 Bionet2_001116 Cc1cc2ncc(C(=O)O)c(n2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C17 compound treatment 0.375 0.121 6.5 6.4972 1.0 1911864 Bionet2_001117 COC(=O)/C=C/c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C18 compound treatment 0.338 0.0839 4.51 4.5089 1.0 1569243 Bionet2_001118 O=C(Nc1ccc2OCOc2c1)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C19 compound treatment 0.311 0.0569 3.06 3.058 1.0 1911865 Bionet2_001119 COC(=O)/C=C/c1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C20 compound treatment 0.411 0.157 8.43 8.4318 1.0 1911866 Bionet2_001120 O=C(Nc1ccc2OCC(=O)Nc2c1)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C21 compound treatment 0.261 0.00691 0.37 0.3711 1.0 1911867 Bionet2_001121 CCOC(=O)c1c(C)nn(c1C)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C22 compound treatment 0.431 0.177 9.51 9.5066 1.0 1911868 Bionet2_001122 CCc1ccc2c(C)cc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C23 mock treatment 0.267 0.0129 0.69 0.6936 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 C24 mock treatment 0.272 0.0179 0.96 0.9622 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D01 compound treatment 0.267 0.0129 0.69 0.6936 1.0 1911869 Bionet2_001123 COc1ccc(/C=C/2\SC(=O)N(C)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D02 compound treatment 0.287 0.0329 1.77 1.7683 1.0 1911870 Bionet2_001124 CCOc1ncccc1C(=O)NCc2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D03 compound treatment 0.258 0.00391 0.21 0.2099 1.0 1911871 Bionet2_001125 OC(=O)CC(C1CCC=CC1)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D04 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1911872 Bionet2_001126 Cc1ccc(C)n1C(CC(=O)O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D05 compound treatment 0.483 0.229 12.3 12.3009 1.0 1911873 Bionet2_001127 CN(C)c1ccc(/C=C/C=N/c2sccc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D06 compound treatment 0.356 0.102 5.48 5.4762 1.0 1911874 Bionet2_001128 Nc1nc2ccccc2cc1c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D07 compound treatment 0.31 0.0559 3.0 3.0043 1.0 1253203 Bionet2_001129 O=C(Nc1sc2CCCCc2c1C#N)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D08 compound treatment 0.295 0.0409 2.2 2.1982 1.0 1911875 Bionet2_001130 Clc1ncc(CSCc2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D09 compound treatment 0.288 0.0339 1.82 1.8221 1.0 1911876 Bionet2_001131 CS(=O)(=O)Nc1cccc2[nH]ncc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D10 compound treatment 0.284 0.0299 1.61 1.6071 1.0 1911877 Bionet2_001132 COc1ccc(CNC(=O)c2oc3ccccc3c2n4cccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D11 compound treatment 0.266 0.0119 0.64 0.6398 1.0 1911878 Bionet2_001133 CN1C(=O)SC(Cc2ccc(N)cc2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D12 compound treatment 0.258 0.00391 0.21 0.2099 1.0 1911879 Bionet2_001134 Cc1ccn2cc(nc2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D13 compound treatment 0.38 0.126 6.77 6.7659 1.0 1911880 Bionet2_001135 Cc1ccc(o1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D14 compound treatment 0.258 0.00391 0.21 0.2099 1.0 1911881 Bionet2_001136 Nc1cc(ccc1NCCC(=O)O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D15 compound treatment 0.434 0.18 9.67 9.6678 1.0 1911882 Bionet2_001137 Fc1ccccc1/C(=C\c2cccc(Oc3ncccn3)c2)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D16 compound treatment 0.299 0.0449 2.41 2.4132 1.0 1911883 Bionet2_001138 FC(F)(F)c1ccc2NCCC(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D17 compound treatment 0.264 0.00991 0.53 0.5323 1.0 1911884 Bionet2_001139 CC(C(=O)O)c1ccc(N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D18 compound treatment 0.328 0.0739 3.97 3.9716 1.0 1911885 Bionet2_001140 Fc1ccc(cc1)C(=O)CCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D19 compound treatment 0.271 0.0169 0.91 0.9085 1.0 1911886 Bionet2_001141 CN1C(=O)SC(Cc2ccc(C#N)cc2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D20 compound treatment 0.462 0.208 11.17 11.1724 1.0 1911887 Bionet2_001142 CSc1nc2nc(ccn2n1)c3ccc4CCCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D21 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1911888 Bionet2_001143 Cc1cccc(c1)C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D22 compound treatment 0.304 0.0499 2.68 2.6819 1.0 1911889 Bionet2_001144 OCCCc1cn2ncc(C#N)c2nc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D23 mock treatment 0.266 0.0119 0.64 0.6398 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 D24 mock treatment 0.245 -0.00909 -0.49 -0.4887 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E01 compound treatment 0.281 0.0269 1.45 1.4459 1.0 1118250 Bionet2_001145 CCC(=O)c1c[nH]c(c1)C(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E02 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1594437 Bionet2_001146 CC(=O)Nc1cc(Cl)c(C)cc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E03 compound treatment 0.244 -0.0101 -0.54 -0.5424 -1.0 1911890 Bionet2_001147 O[C@H](CN1CCC2(CC1)OCCO2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E04 compound treatment 0.274 0.0199 1.07 1.0697 1.0 1277269 Bionet2_001148 Clc1ccc(cc1)C(=O)Nc2ccc(cc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E05 compound treatment 0.442 0.188 10.1 10.0977 1.0 1911891 Bionet2_001149 c1ccn(c1)c2ccc3nccnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E06 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1395054 Bionet2_001150 COC(=O)CC1COc2ccccc2N1C(=O)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E07 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1122738 Bionet2_001151 CCC(CC)C(=O)c1c[nH]c(c1)C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E08 compound treatment 0.417 0.163 8.75 8.7542 1.0 1911892 Bionet2_001152 O=C(NCCCn1ccnc1)c2cc(c[nH]2)C(=O)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E09 compound treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1624834 Bionet2_001153 Cc1ccccc1C(CC(=O)O)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E10 compound treatment 0.31 0.0559 3.0 3.0043 1.0 1911893 Bionet2_001154 C1Oc2ccc(cc2O1)c3ccn[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E11 compound treatment 0.511 0.257 13.81 13.8056 1.0 1911894 Bionet2_001155 COC(=O)/C=C/c1cncc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E12 compound treatment 0.286 0.0319 1.71 1.7146 1.0 1911895 Bionet2_001156 C[C@H](NC(=O)Cc1ncc(cc1Cl)C(F)(F)F)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E13 compound treatment 0.264 0.00991 0.53 0.5323 1.0 1594869 Bionet2_001157 OC(=O)CC(N1Cc2ccccc2C1=O)c3cccc(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E14 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1911896 Bionet2_001158 N#Cc1ccccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E15 compound treatment 0.323 0.0689 3.7 3.7029 1.0 1364920 Bionet2_001159 Fc1ccc(Cn2cc(CCN3CCS(=O)(=O)CC3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E16 compound treatment 0.392 0.138 7.41 7.4108 1.0 1911897 Bionet2_001160 COc1ccc(cc1)c2csc(n2)n3nc(C)cc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E17 compound treatment 0.282 0.0279 1.5 1.4996 1.0 1060495 Bionet2_001161 Brc1ccc(cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E18 compound treatment 0.282 0.0279 1.5 1.4996 1.0 1911898 Bionet2_001162 OC(CCN1CCN(CC1)C(c2ccccc2)c3ccccc3)C(F)(F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E19 compound treatment 0.292 0.0379 2.04 2.037 1.0 1911899 Bionet2_001163 COC(=O)CC(c1ccc(Br)cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E20 compound treatment 0.482 0.228 12.25 12.2472 1.0 1911900 Bionet2_001164 COc1ccc(CNC(=O)c2c[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E21 compound treatment 0.274 0.0199 1.07 1.0697 1.0 1365185 Bionet2_001165 Cc1ccc(C)c(c1)n2ncc(c2O)n3cncn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E22 compound treatment 0.313 0.0589 3.17 3.1655 1.0 1911901 Bionet2_001166 CCc1ccc2c(cc(=O)oc2c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E23 mock treatment 0.264 0.00991 0.53 0.5323 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 E24 mock treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F01 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1911902 Bionet2_001167 CCN1C(=O)S/C(=C\c2cccc(Cl)c2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F02 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1911903 Bionet2_001168 OC(=O)CC(c1ccc(Br)cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F03 compound treatment 0.256 0.00191 0.1 0.1024 1.0 1911904 Bionet2_001169 CCC(CC)C(CC(=O)O)N1Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F04 compound treatment 0.363 0.109 5.85 5.8524 1.0 1911905 Bionet2_001170 Cc1nc(cn1Cc2ccc(F)cc2)c3ccc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F05 compound treatment 0.266 0.0119 0.64 0.6398 1.0 1911906 Bionet2_001171 N/C(=N\O)/c1ccccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F06 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1022481 Bionet2_001172 OC(=O)c1ccccc1C(=O)c2ccc3CCCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F07 compound treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1911907 Bionet2_001173 Cc1ccc(C)n1NC(=O)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F08 compound treatment 0.332 0.0779 4.19 4.1865 1.0 1911908 Bionet2_001174 CN1C(=O)S/C(=C\C=C\c2ccccc2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F09 compound treatment 0.402 0.148 7.95 7.9482 1.0 1911909 Bionet2_001175 Oc1cccc(c1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F10 compound treatment 0.366 0.112 6.01 6.0136 1.0 1911910 Bionet2_001176 Cc1ccc(COc2coc(CO)cc2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F11 compound treatment 0.334 0.0799 4.29 4.294 1.0 1911911 Bionet2_001177 COc1cccc2c(Cl)c(CCCl)c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F12 compound treatment 0.274 0.0199 1.07 1.0697 1.0 1911912 Bionet2_001178 CCOC(=O)CC(c1ccc(N)cc1)n2c(C)ccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F13 compound treatment 0.315 0.0609 3.27 3.273 1.0 1911913 Bionet2_001179 Brc1ccc(s1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F14 compound treatment 0.515 0.261 14.02 14.0206 1.0 1911914 Bionet2_001180 Cc1ccnc(n1)S(=O)(=O)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F15 compound treatment 0.246 -0.00809 -0.43 -0.4349 -1.0 1911915 Bionet2_001181 Cc1nn(C)c(Cl)c1NC(=O)OCC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F16 compound treatment 0.399 0.145 7.79 7.787 1.0 1911916 Bionet2_001182 COc1cccc2[nH]c(=O)c(cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F17 compound treatment 0.268 0.0139 0.75 0.7473 1.0 1911917 Bionet2_001183 Brc1cc(Br)c2nc(ccc2c1)c3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F18 compound treatment 0.354 0.0999 5.37 5.3688 1.0 1911918 Bionet2_001184 Cc1ccc(CN2C(=O)CCNc3ccc(cc23)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F19 compound treatment 0.292 0.0379 2.04 2.037 1.0 1911919 Bionet2_001185 Cc1nc2c(C#N)c(ccn2n1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F20 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1911920 Bionet2_001186 COc1ccc(cc1OC)C(N)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F21 compound treatment 0.251 -0.00309 -0.17 -0.1663 -1.0 1911921 Bionet2_001187 NC(CC(=O)O)c1ccsc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F22 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1911922 Bionet2_001188 Cn1nc(c(CNC(=O)c2ccc(cc2)C(F)(F)F)c1N3CCOCC3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F23 mock treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 F24 mock treatment 0.229 -0.0251 -1.35 -1.3485 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G01 compound treatment 0.355 0.101 5.42 5.4225 1.0 1911923 Bionet2_001189 CCC(=O)c1c[nH]c(c1)C(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G02 compound treatment 0.308 0.0539 2.9 2.8968 1.0 1911924 Bionet2_001190 FC(F)(F)c1cccc(c1)C(=O)NCCN2CCN(CC2)C(=O)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G03 compound treatment 0.306 0.0519 2.79 2.7893 1.0 1204294 Bionet2_001191 COc1ccc(cc1)C(=O)Nc2ccc(N3CCOCC3)c(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G04 compound treatment 0.265 0.0109 0.59 0.5861 1.0 1911925 Bionet2_001192 Clc1nc(nc2ccsc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G05 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1403054 Bionet2_001193 OC(=O)CC(N1Cc2ccccc2C1=O)c3ccc(Cl)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G06 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1911926 Bionet2_001194 Cc1cc(n(n1)c2nc(CCl)cs2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G07 compound treatment 0.28 0.0259 1.39 1.3921 1.0 1703175 Bionet2_001195 CCC(CC)C(=O)c1c[nH]c(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G08 compound treatment 0.403 0.149 8.0 8.0019 1.0 1911927 Bionet2_001196 Brc1ccc(cc1)c2cn3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G09 compound treatment 0.256 0.00191 0.1 0.1024 1.0 1709618 Bionet2_001197 OC(=O)CC(N1Cc2ccccc2C1=O)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G10 compound treatment 0.358 0.104 5.58 5.5837 1.0 1911928 Bionet2_001198 COC(=O)c1ccc(cc1)c2cnco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G11 compound treatment 0.423 0.169 9.08 9.0767 1.0 1263687 Bionet2_001199 Ic1ccc2nc(cn2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G12 compound treatment 0.311 0.0569 3.06 3.058 1.0 1177278 Bionet2_001200 CC(C)(C)c1ccc(Cn2cnc(C#N)c2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G13 compound treatment 0.251 -0.00309 -0.17 -0.1663 -1.0 1613534 Bionet2_001201 CCc1ccc(cc1)C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G14 compound treatment 0.317 0.0629 3.38 3.3805 1.0 1911929 Bionet2_001202 FC(F)(F)C(=O)Nc1ccc(C#Cc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G15 compound treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1911930 Bionet2_001203 Cc1ccc(C)n1CCc2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G16 compound treatment 0.369 0.115 6.17 6.1748 1.0 1911931 Bionet2_001204 Clc1ccc(cc1)c2cnc3SC[C@@H](CBr)[n+]3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G17 compound treatment 0.367 0.113 6.07 6.0673 1.0 1911932 Bionet2_001205 COC(=O)/C=C/c1cccc(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G18 compound treatment 0.354 0.0999 5.37 5.3688 1.0 1911933 Bionet2_001206 Cc1cc(C)n(n1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G19 compound treatment 0.391 0.137 7.36 7.3571 1.0 1911934 Bionet2_001207 O/N=C/c1ccn(c1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G20 compound treatment 0.383 0.129 6.93 6.9272 1.0 1911935 Bionet2_001208 Clc1ccc(CNC(=O)c2c[nH]c3ccccc23)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G21 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1911936 Bionet2_001209 O=C(Cn1cncn1)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G22 compound treatment 0.275 0.0209 1.12 1.1235 1.0 1911937 Bionet2_001210 COC(=O)CC1COc2ccccc2N1C(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G23 mock treatment 0.267 0.0129 0.69 0.6936 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 G24 mock treatment 0.255 9.06E-4 0.05 0.0487 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H01 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1911938 Bionet2_001211 Clc1cnc(c(Br)c1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H02 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1911939 Bionet2_001212 OC(=O)CC(c1ccsc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H03 compound treatment 0.521 0.267 14.34 14.343 1.0 1911940 Bionet2_001213 COc1ccc(cc1)S(=O)(=O)n2ccc(n2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H04 compound treatment 0.427 0.173 9.29 9.2916 1.0 1911941 Bionet2_001214 Cc1c(sc2ncnn12)c3ccc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H05 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1911942 Bionet2_001215 NC(CC(=O)O)C1CCC=CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H06 compound treatment 0.327 0.0729 3.92 3.9178 1.0 1911943 Bionet2_001216 O=C1OC(c2ccccc12)c3ccc4CCCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H07 compound treatment 0.442 0.188 10.1 10.0977 1.0 1911944 Bionet2_001217 O=C1NC(=O)C(Cc2ccccc2)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H08 compound treatment 0.292 0.0379 2.04 2.037 1.0 1911945 Bionet2_001218 CNc1nc(cs1)c2cccc(N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H09 compound treatment 0.291 0.0369 1.98 1.9833 1.0 1911946 Bionet2_001219 Cc1cc2ccccc2nc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H10 compound treatment 0.53 0.276 14.83 14.8266 1.0 1911947 Bionet2_001220 CC1(C)CN(C1=O)c2cccc(c2)C(=O)c3cn(nn3)c4ccc(cc4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H11 compound treatment 0.276 0.0219 1.18 1.1772 1.0 1911948 Bionet2_001221 Clc1cnc(nc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H12 compound treatment 0.261 0.00691 0.37 0.3711 1.0 1911949 Bionet2_001222 COCc1cc(Cl)nc2cc(NC(=O)C(F)(F)F)c(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H13 compound treatment 0.318 0.0639 3.43 3.4342 1.0 1911950 Bionet2_001223 Brc1ccc(cc1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H14 compound treatment 0.267 0.0129 0.69 0.6936 1.0 1911951 Bionet2_001224 CN1CCN(CC1)c2ccc(cc2N)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H15 compound treatment 0.301 0.0469 2.52 2.5206 1.0 1911952 Bionet2_001225 Cc1cc(nc(n1)n2cccc2)c3ccc(Cl)s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H16 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1732332 Bionet2_001226 Cc1ccc(s1)C(=O)c2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H17 compound treatment 0.272 0.0179 0.96 0.9622 1.0 1911953 Bionet2_001227 Cc1cc2ccccc2nc1c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H18 compound treatment 0.489 0.235 12.62 12.6234 1.0 1911954 Bionet2_001228 COC(=O)c1ccc2N3CCCC3C(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H19 compound treatment 0.304 0.0499 2.68 2.6819 1.0 1911955 Bionet2_001229 FC(F)(F)c1cccc(c1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H20 compound treatment 0.37 0.116 6.23 6.2286 1.0 1911956 Bionet2_001230 COc1ccc2-c3n[nH]cc3CCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H21 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1390357 Bionet2_001231 CSc1ccc(cc1)C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H22 compound treatment 0.455 0.201 10.8 10.7963 1.0 1911957 Bionet2_001232 COC(=O)c1ccc2nc(cn2c1)c3cccc(N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H23 mock treatment 0.272 0.0179 0.96 0.9622 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 H24 mock treatment 0.255 9.06E-4 0.05 0.0487 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I01 compound treatment 0.387 0.133 7.14 7.1421 1.0 1217311 Bionet2_001233 CCC(=O)c1c[nH]c(c1)C(=O)Nc2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I02 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1553580 Bionet2_001234 Clc1cccc(c1)c2nc3ccc(cc3c(=O)[nH]2)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I03 compound treatment 0.285 0.0309 1.66 1.6608 1.0 1911958 Bionet2_001235 CCOC(=O)c1c(C)nn(c1C)c2ccnc3cc(Cl)ccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I04 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1549304 Bionet2_001236 Cc1ccc(CSc2nnc3c4ccccc4[nH]c3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I05 compound treatment 0.243 -0.0111 -0.6 -0.5962 -1.0 1223364 Bionet2_001237 OC(=O)CC(N1Cc2ccccc2C1=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I06 compound treatment 0.276 0.0219 1.18 1.1772 1.0 1911959 Bionet2_001238 Cn1ncc(C(=O)CC#N)c1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I07 compound treatment 0.393 0.139 7.46 7.4645 1.0 1530948 Bionet2_001239 Cc1ccccc1C(=O)c2c[nH]c(c2)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I08 compound treatment 0.304 0.0499 2.68 2.6819 1.0 1440120 Bionet2_001240 Fc1ccc(CNC(=O)c2cc(c[nH]2)C(=O)c3ccc(F)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I09 compound treatment 0.294 0.0399 2.14 2.1445 1.0 1270771 Bionet2_001241 COC(=O)CC(N1Cc2ccccc2C1=O)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I10 compound treatment 0.422 0.168 9.02 9.0229 1.0 1911960 Bionet2_001242 c1cnn(c1)c2ccc(cc2)c3cnco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I11 compound treatment 0.275 0.0209 1.12 1.1235 1.0 1911961 Bionet2_001243 Cc1cc(C)c2c(n[nH]c2n1)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I12 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1911962 Bionet2_001244 OC(=O)/C=C\c1cccn1c2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I13 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1454068 Bionet2_001245 CC(=O)N1CCC(CC1)C(=O)c2c(C)c(C)c(C)c(C)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I14 compound treatment 0.513 0.259 13.91 13.9131 1.0 1911963 Bionet2_001246 OC(=O)c1cc2ccc(Br)cc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I15 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1161471 Bionet2_001247 CCCCN1C(C(CCC1=O)C(=O)O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I16 compound treatment 0.531 0.277 14.88 14.8804 1.0 1911964 Bionet2_001248 Cc1cccc(N/C=C/C(=O)c2cccs2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I17 compound treatment 0.319 0.0649 3.49 3.4879 1.0 1911965 Bionet2_001249 CC(Oc1ccc(Cl)cc1Cl)c2ccnc3cc(C)nn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I18 compound treatment 0.266 0.0119 0.64 0.6398 1.0 1911966 Bionet2_001250 FC(F)(F)c1cc(n2nc(cc2n1)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I19 compound treatment 0.299 0.0449 2.41 2.4132 1.0 1911967 Bionet2_001251 COC(=O)c1cccn1c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I20 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1911968 Bionet2_001252 CC(NC(=O)c1c[nH]c2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I21 compound treatment 0.264 0.00991 0.53 0.5323 1.0 1911969 Bionet2_001253 Cc1nc2ncnn2c(C)c1Cc3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I22 compound treatment 0.295 0.0409 2.2 2.1982 1.0 1911970 Bionet2_001254 COC(=O)CC1COc2ccccc2N1C(=O)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I23 mock treatment 0.265 0.0109 0.59 0.5861 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 I24 mock treatment 0.271 0.0169 0.91 0.9085 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J01 compound treatment 0.24 -0.0141 -0.76 -0.7574 -1.0 1911971 Bionet2_001255 COC(=O)C(NC(=O)c1c(C)nn(C)c1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J02 compound treatment 0.251 -0.00309 -0.17 -0.1663 -1.0 1911972 Bionet2_001256 OC(=O)CC(C1CCCCC1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J03 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1911973 Bionet2_001257 Cn1cc(C(=O)N2CCOCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J04 compound treatment 0.286 0.0319 1.71 1.7146 1.0 1911974 Bionet2_001258 CC1=NC(=C(NC(C1)c2c(F)cccc2Cl)C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J05 compound treatment 0.503 0.249 13.38 13.3757 1.0 1911975 Bionet2_001259 Cc1ccc(/C=C/2\SC(=O)NC2=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J06 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1911976 Bionet2_001260 Nc1cccnc1n2nc(cc2C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J07 compound treatment 0.281 0.0269 1.45 1.4459 1.0 1911977 Bionet2_001261 CC(C)Oc1cccc(NC(=O)Cc2ncc(cc2Cl)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J08 compound treatment 0.365 0.111 5.96 5.9599 1.0 1911978 Bionet2_001262 Cc1nc2ccc(NC(=O)c3cccc(c3)C(F)(F)F)cc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J09 compound treatment 0.452 0.198 10.64 10.6351 1.0 1911979 Bionet2_001263 c1cc(n[nH]1)c2cc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J10 compound treatment 0.273 0.0189 1.02 1.016 1.0 1911980 Bionet2_001264 OC1CC(NC(=O)C(F)(F)F)c2ccsc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J11 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1911981 Bionet2_001265 Oc1ccccc1Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J12 compound treatment 0.322 0.0679 3.65 3.6491 1.0 1911982 Bionet2_001266 CC1(C)CC(=O)C(=CNc2ccc(OC(F)(F)F)cc2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J13 compound treatment 0.31 0.0559 3.0 3.0043 1.0 1911983 Bionet2_001267 COc1cc(CCC(O)c2ccc(C)cc2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J14 compound treatment 0.283 0.0289 1.55 1.5534 1.0 1911984 Bionet2_001268 Nc1ccccc1Cn2cccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J15 compound treatment 0.305 0.0509 2.74 2.7356 1.0 1911985 Bionet2_001269 COc1cccc2c3SCCc3c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J16 compound treatment 0.394 0.14 7.52 7.5183 1.0 1303151 Bionet2_001270 COc1ccc(cc1)C(=O)NCCc2c[nH]c3ccc(OC)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J17 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1911986 Bionet2_001271 Cc1cc(C)c(C#N)c(n1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J18 compound treatment 0.309 0.0549 2.95 2.9505 1.0 1911987 Bionet2_001272 OC(=O)c1ccc2N3CCCC3C(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J19 compound treatment 0.439 0.185 9.94 9.9365 1.0 1911988 Bionet2_001273 Nc1nc2ccccc2cc1S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J20 compound treatment 0.307 0.0529 2.84 2.8431 1.0 1911989 Bionet2_001274 COC(=O)c1[nH]c2ccccc2c1I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J21 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1911990 Bionet2_001275 FC(F)(F)C(=O)NC1CNC(=O)c2cc3OCOc3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J22 compound treatment 0.263 0.00891 0.48 0.4786 1.0 1911991 Bionet2_001276 Cc1nc2nc(cc(O)n2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J23 mock treatment 0.255 9.06E-4 0.05 0.0487 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 J24 mock treatment 0.241 -0.0131 -0.7 -0.7036 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K01 compound treatment 0.339 0.0849 4.56 4.5627 1.0 1221634 Bionet2_001277 CCC(=O)c1c[nH]c(c1)C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K02 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1731204 Bionet2_001278 OC(=O)c1cccn1c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K03 compound treatment 0.247 -0.00709 -0.38 -0.3812 -1.0 1479290 Bionet2_001279 C1Cc2[nH]cnc2C(N1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K04 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1911992 Bionet2_001280 FC(F)(F)c1nnc(nc1Oc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K05 compound treatment 0.209 -0.0451 -2.42 -2.4232 -1.0 1551208 Bionet2_001281 CC(C)(C)c1cc(=O)[nH]c(SCc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K06 compound treatment 0.24 -0.0141 -0.76 -0.7574 -1.0 1911993 Bionet2_001282 O/N=C(/NCc1ccccc1)\c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K07 compound treatment 0.372 0.118 6.34 6.336 1.0 1911994 Bionet2_001283 O=C(Cc1ccccc1)c2c[nH]c(c2)C(=O)NCCCn3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K08 compound treatment 0.263 0.00891 0.48 0.4786 1.0 1911995 Bionet2_001284 CC(C(=O)NCc1ccncc1)n2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K09 compound treatment 0.245 -0.00909 -0.49 -0.4887 -1.0 1911996 Bionet2_001285 CC(C(=O)O)n1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K10 compound treatment 0.483 0.229 12.3 12.3009 1.0 1422199 Bionet2_001286 COc1cccc(c1)C(=O)c2c[nH]c(c2)C(=O)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K11 compound treatment 0.243 -0.0111 -0.6 -0.5962 -1.0 1911997 Bionet2_001287 Cc1cc(C)n(n1)c2ncccc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K12 compound treatment 0.288 0.0339 1.82 1.8221 1.0 1911998 Bionet2_001288 Fc1ccc(cc1)C(=O)c2cn(nn2)c3ccc(F)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K13 compound treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1432746 Bionet2_001289 OC(=O)C1CCC(=O)N(C2CCCCC2)C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K14 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1638822 Bionet2_001290 COC(C(=O)OC)c1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K15 compound treatment 0.43 0.176 9.45 9.4528 1.0 1911999 Bionet2_001291 FC(F)(F)c1ccc(Cn2cc(CCN3CCS(=O)(=O)CC3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K16 compound treatment 0.518 0.264 14.18 14.1818 1.0 1912000 Bionet2_001292 C/C(=N\c1cc(C)n[nH]1)/C2CCOC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K17 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1912001 Bionet2_001293 FC(F)(F)Oc1ccc(cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K18 compound treatment 0.278 0.0239 1.28 1.2847 1.0 1912002 Bionet2_001294 O=C(Nc1ccsc1C(=O)N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K19 compound treatment 0.273 0.0189 1.02 1.016 1.0 1912003 Bionet2_001295 FC(F)(F)c1cnc(CC(=O)NCc2ccco2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K20 compound treatment 0.433 0.179 9.61 9.614 1.0 1912004 Bionet2_001296 COc1ccccc1NC(=O)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K21 compound treatment 0.289 0.0349 1.88 1.8758 1.0 1912005 Bionet2_001297 CSc1nc2nc(C)c(Cc3cccc(F)c3)c(C)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K22 compound treatment 0.474 0.22 11.82 11.8173 1.0 1912006 Bionet2_001298 COc1ccc(cc1F)c2n[nH]cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K23 mock treatment 0.257 0.00291 0.16 0.1562 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 K24 mock treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L01 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1912007 Bionet2_001299 COC(=O)C(NC(=O)c1cn(C)nc1C(F)(F)F)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L02 compound treatment 0.453 0.199 10.69 10.6888 1.0 1912008 Bionet2_001300 O=C1COc2ccc(cc2N1)N3Cc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L03 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1912009 Bionet2_001301 CCn1cc(C(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L04 compound treatment 0.277 0.0229 1.23 1.2309 1.0 1912010 Bionet2_001302 COc1ccc(cc1F)c2nc3c(C#N)cnn3cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L05 compound treatment 0.352 0.0979 5.26 5.2613 1.0 1912011 Bionet2_001303 Cc1cc(C)c(C#N)c(OCc2cccc(c2)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L06 compound treatment 0.305 0.0509 2.74 2.7356 1.0 1912012 Bionet2_001304 Brc1ccsc1c2ccn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L07 compound treatment 0.25 -0.00409 -0.22 -0.22 -1.0 1912013 Bionet2_001305 FC(F)(F)c1cnc(CC(=O)Nc2ccc(cc2)N3CCOCC3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L08 compound treatment 0.287 0.0329 1.77 1.7683 1.0 1912014 Bionet2_001306 COc1ccccc1c2cc(nc(C)c2C#N)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L09 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1912015 Bionet2_001307 Cc1ccc(cc1)C(=O)CSc2nc(cc(=O)n2c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L10 compound treatment 0.347 0.0929 4.99 4.9926 1.0 1912016 Bionet2_001308 Cc1ccc(CNC(=O)c2oc3ccccc3c2n4cccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L11 compound treatment 0.272 0.0179 0.96 0.9622 1.0 1912017 Bionet2_001309 COC(=O)c1cc(Br)c(cc1OC)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L12 compound treatment 0.374 0.12 6.44 6.4435 1.0 1912018 Bionet2_001310 C/C(=C\1/CCOC1=O)/Nc2ccc(OC(F)(F)F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L13 compound treatment 0.49 0.236 12.68 12.6771 1.0 1176448 Bionet2_001311 CCOC(=O)c1c(Cl)c2ccccc2n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L14 compound treatment 0.311 0.0569 3.06 3.058 1.0 1912019 Bionet2_001312 COC(=O)CC(c1ccc(C#N)cc1)n2c(C)ccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L15 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1912020 Bionet2_001313 OCCC1Oc2cccnc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L16 compound treatment 0.244 -0.0101 -0.54 -0.5424 -1.0 1912021 Bionet2_001314 FC(F)(F)c1cnc(CC(=O)NCCN2CCCCC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L17 compound treatment 0.31 0.0559 3.0 3.0043 1.0 1272110 Bionet2_001315 COC(=O)c1ccccc1OCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L18 compound treatment 0.266 0.0119 0.64 0.6398 1.0 1433820 Bionet2_001316 CC1=C(C#N)C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L19 compound treatment 0.256 0.00191 0.1 0.1024 1.0 1912022 Bionet2_001317 CS(=O)(=O)c1cc2ccccc2nc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L20 compound treatment 0.463 0.209 11.23 11.2262 1.0 1912023 Bionet2_001318 Oc1cc(OCc2cccc(c2)C(F)(F)F)ccc1c3cc[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L21 compound treatment 0.283 0.0289 1.55 1.5534 1.0 1912024 Bionet2_001319 COc1ccc(cc1OC)c2cnn3ccc(nc23)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L22 compound treatment 0.277 0.0229 1.23 1.2309 1.0 1912025 Bionet2_001320 CCOC(=O)c1ccc(nc1C)c2ccc3CCCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L23 mock treatment 0.26 0.00591 0.32 0.3174 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 L24 mock treatment 0.238 -0.0161 -0.86 -0.8648 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M01 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1912026 Bionet2_001321 CCOC(=O)c1cnn(c1n2cccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M02 compound treatment 0.251 -0.00309 -0.17 -0.1663 -1.0 1912027 Bionet2_001322 O/N=C/c1cccn1c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M03 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1624814 Bionet2_001323 CCCCN1C(C(CCC1=O)C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M04 compound treatment 0.47 0.216 11.6 11.6024 1.0 1912028 Bionet2_001324 Fc1ccccc1c2cn3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M05 compound treatment 0.271 0.0169 0.91 0.9085 1.0 1185909 Bionet2_001325 CCOc1ccc(cc1)C(CC(=O)O)N2Cc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M06 compound treatment 0.375 0.121 6.5 6.4972 1.0 1725427 Bionet2_001326 CCOC(=O)CC1COc2ccccc2N1C(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M07 compound treatment 0.312 0.0579 3.11 3.1118 1.0 1419923 Bionet2_001327 COC(=O)c1cc(c[nH]1)C(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M08 compound treatment 0.312 0.0579 3.11 3.1118 1.0 1912029 Bionet2_001328 Cn1nc(c(CNc2ccc(Cl)cc2)c1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M09 compound treatment 0.457 0.203 10.9 10.9038 1.0 1504497 Bionet2_001329 CCN1CCN(CC1)c2ccc(NC(=O)c3ccc(C)cc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M10 compound treatment 0.283 0.0289 1.55 1.5534 1.0 1912030 Bionet2_001330 CCC(=O)c1c[nH]c(c1)C(=O)NCc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M11 compound treatment 0.295 0.0409 2.2 2.1982 1.0 1912031 Bionet2_001331 Cc1nc2ncnn2c(C)c1Cc3c(Cl)cccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M12 compound treatment 0.422 0.168 9.02 9.0229 1.0 1734142 Bionet2_001332 O=C(NCc1ccco1)c2cc(c[nH]2)C(=O)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M13 compound treatment 0.279 0.0249 1.34 1.3384 1.0 1742109 Bionet2_001333 Cc1nc2c(C#N)ncn2c(C)c1Cc3cccc(F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M14 compound treatment 0.263 0.00891 0.48 0.4786 1.0 1912032 Bionet2_001334 N#Cc1cccn1c2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M15 compound treatment 0.31 0.0559 3.0 3.0043 1.0 1601132 Bionet2_001335 Cc1cc(C)c2c(nn(CC#N)c2n1)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M16 compound treatment 0.328 0.0739 3.97 3.9716 1.0 1912033 Bionet2_001336 CCC(=O)c1c[nH]c(c1)C(=O)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M17 compound treatment 0.275 0.0209 1.12 1.1235 1.0 1912034 Bionet2_001337 CC(C)c1ccc(/C=C\C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M18 compound treatment 0.271 0.0169 0.91 0.9085 1.0 1912035 Bionet2_001338 O=C(N1CCOCC1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M19 compound treatment 0.259 0.00491 0.26 0.2637 1.0 1327157 Bionet2_001339 Nc1nccc(n1)c2ccccc2OCc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M20 compound treatment 0.372 0.118 6.34 6.336 1.0 1912036 Bionet2_001340 O=C(N1CCCC1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M21 compound treatment 0.278 0.0239 1.28 1.2847 1.0 1613749 Bionet2_001341 Cc1ccc(cc1)c2nc3ccc(cc3c(=O)[nH]2)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M22 compound treatment 0.464 0.21 11.28 11.2799 1.0 1912037 Bionet2_001342 O=C(/C=C/c1cccs1)/C=C/c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M23 mock treatment 0.262 0.00791 0.42 0.4249 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 M24 mock treatment 0.255 9.06E-4 0.05 0.0487 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N01 compound treatment 0.311 0.0569 3.06 3.058 1.0 1912038 Bionet2_001343 CCNc1nc2ccccc2n1Cc3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N02 compound treatment 0.553 0.299 16.06 16.0626 1.0 1912039 Bionet2_001344 Cc1nc(nc2CCCCc12)n3cc(nn3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N03 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1912040 Bionet2_001345 CNC(=O)c1cn(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N04 compound treatment 0.259 0.00491 0.26 0.2637 1.0 1912041 Bionet2_001346 CCCc1c(C)nn(c1C)c2ncccc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N05 compound treatment 0.533 0.279 14.99 14.9878 1.0 1912042 Bionet2_001347 O=C1NC(=O)/C(=C\c2ccccc2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N06 compound treatment 0.529 0.275 14.77 14.7729 1.0 1912043 Bionet2_001348 COc1ccc(cc1)C(=O)COc2ccccc2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N07 compound treatment 0.245 -0.00909 -0.49 -0.4887 -1.0 1912044 Bionet2_001349 O=C(Nc1cccc2[nH]ncc12)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N08 compound treatment 0.285 0.0309 1.66 1.6608 1.0 1912045 Bionet2_001350 Cc1ccc(C)n1c2ccc(cc2)c3cc[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N09 compound treatment 0.248 -0.00609 -0.33 -0.3275 -1.0 1912046 Bionet2_001351 OC1CC(NC(=O)C(F)(F)F)c2cc3OCOc3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N10 compound treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1912047 Bionet2_001352 Cc1ccc(C)n1C(CC(=O)O)c2ccsc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N11 compound treatment 0.32 0.0659 3.54 3.5417 1.0 1912048 Bionet2_001353 Cc1nc2ccc(cc2o1)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N12 compound treatment 0.275 0.0209 1.12 1.1235 1.0 1912049 Bionet2_001354 C/C(=C\1/CCOC1=O)/Nc2ccccc2Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N13 compound treatment 0.415 0.161 8.65 8.6468 1.0 1912050 Bionet2_001355 Cc1nc2ccccc2cc1OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N14 compound treatment 0.313 0.0589 3.17 3.1655 1.0 1912051 Bionet2_001356 COc1cccc(Cn2c(=O)c3ccccc3n4nc(C)cc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N15 compound treatment 0.398 0.144 7.73 7.7332 1.0 1912052 Bionet2_001357 Cc1nc2ccc(NC(=O)c3cccs3)cc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N16 compound treatment 0.257 0.00291 0.16 0.1562 1.0 1451730 Bionet2_001358 Cc1cc(C)n(n1)C(=O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N17 compound treatment 0.259 0.00491 0.26 0.2637 1.0 1912053 Bionet2_001359 COc1ccccc1C2C3=C(CC(C)(C)CC3=O)Nc4n[nH]c(C)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N18 compound treatment 0.313 0.0589 3.17 3.1655 1.0 1912054 Bionet2_001360 Nc1ccccc1/C=C/2\C(=O)Nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N19 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1912055 Bionet2_001361 CC(C)c1ccc(cc1)C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N20 compound treatment 0.294 0.0399 2.14 2.1445 1.0 1912056 Bionet2_001362 Cc1ccc2OC(CCCl)C(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N21 compound treatment 0.251 -0.00309 -0.17 -0.1663 -1.0 1912057 Bionet2_001363 O/N=C/1\CC(NC(=O)C(F)(F)F)c2ccsc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N22 compound treatment 0.493 0.239 12.84 12.8383 1.0 1912058 Bionet2_001364 FC(F)(F)c1ccc2N3CCCC3C(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N23 mock treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 N24 mock treatment 0.236 -0.0181 -0.97 -0.9723 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O01 compound treatment 0.369 0.115 6.17 6.1748 1.0 1733103 Bionet2_001365 CCCCc1ccc(cc1)c2csc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O02 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1680580 Bionet2_001366 NC(CC(=O)O)c1ccc(C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O03 compound treatment 0.264 0.00991 0.53 0.5323 1.0 1912059 Bionet2_001367 CCOC(=O)c1c(C)nn(c1C)c2ncccc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O04 compound treatment 0.24 -0.0141 -0.76 -0.7574 -1.0 1912060 Bionet2_001368 Cc1ccc(F)cc1NC(=O)Cc2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O05 compound treatment 0.255 9.06E-4 0.05 0.0487 1.0 1617757 Bionet2_001369 OC(=O)CC(N1Cc2ccccc2C1=O)c3ccccc3Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O06 compound treatment 0.305 0.0509 2.74 2.7356 1.0 1677078 Bionet2_001370 CC1(C)CN(C1=O)c2cccc(c2)c3ccnc4ncnn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O07 compound treatment 0.258 0.00391 0.21 0.2099 1.0 1525435 Bionet2_001371 COc1ccc(CNC(=O)c2ccc[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O08 compound treatment 0.249 -0.00509 -0.27 -0.2737 -1.0 1912061 Bionet2_001372 Cc1cc(C)cc(/N=C/c2c(Cl)n(C)nc2C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O09 compound treatment 0.26 0.00591 0.32 0.3174 1.0 1912062 Bionet2_001373 CC(C(=O)NC(C)(C)C)n1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O10 compound treatment 0.283 0.0289 1.55 1.5534 1.0 1912063 Bionet2_001374 Fc1ccc(cc1)N2CCN(CC2)C(=O)Cc3ncc(cc3Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O11 compound treatment 0.504 0.25 13.43 13.4294 1.0 1397817 Bionet2_001375 Cn1cc(cc1C(=O)O)C(=O)c2cccc(Cl)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O12 compound treatment 0.278 0.0239 1.28 1.2847 1.0 1646239 Bionet2_001376 COc1ccc(cc1)c2cnc3cc(C)nn3c2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O13 compound treatment 0.274 0.0199 1.07 1.0697 1.0 1264319 Bionet2_001377 Nc1nccc(n1)c2cccc(OCc3c(F)cccc3Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O14 compound treatment 0.334 0.0799 4.29 4.294 1.0 1740721 Bionet2_001378 CCOC(=O)c1cnc2n(C)ncc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O15 compound treatment 0.345 0.0909 4.89 4.8851 1.0 1228537 Bionet2_001379 COC(=O)c1cc(c[nH]1)C(=O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O16 compound treatment 0.358 0.104 5.58 5.5837 1.0 1912064 Bionet2_001380 OC(=O)c1cccnc1Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O17 compound treatment 0.283 0.0289 1.55 1.5534 1.0 1912065 Bionet2_001381 O=c1oc(nc2ccsc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O18 compound treatment 0.271 0.0169 0.91 0.9085 1.0 1912066 Bionet2_001382 CC(=O)Oc1cc(nn1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O19 compound treatment 0.254 -9.38E-5 -0.01 -0.005 -1.0 1193610 Bionet2_001383 CN(C)CCC(O)c1cc(Cl)sc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O20 compound treatment 0.41 0.156 8.38 8.3781 1.0 1912067 Bionet2_001384 O=C(N1CCN(CC1)c2ccccc2)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O21 compound treatment 0.271 0.0169 0.91 0.9085 1.0 1912068 Bionet2_001385 Clc1cc(CS(=O)c2ccccc2)nc(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O22 compound treatment 0.275 0.0209 1.12 1.1235 1.0 1912069 Bionet2_001386 COc1ccc(cc1OC)c2cnn3c(Cl)c(CCCl)c(C)nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O23 mock treatment 0.252 -0.00209 -0.11 -0.1125 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 O24 mock treatment 0.247 -0.00709 -0.38 -0.3812 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P01 compound treatment 0.236 -0.0181 -0.97 -0.9723 -1.0 1912070 Bionet2_001387 Cc1nn(C)c(Cl)c1C(=O)NCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P02 compound treatment 0.235 -0.0191 -1.03 -1.0261 -1.0 1912071 Bionet2_001388 COCc1cc(=O)[nH]c2cc(NC(=O)C(F)(F)F)c(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P03 compound treatment 0.253 -0.00109 -0.06 -0.0588 -1.0 1912072 Bionet2_001389 OC(=O)c1cn(Cc2ccc(Cl)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P04 compound treatment 0.291 0.0369 1.98 1.9833 1.0 1912073 Bionet2_001390 Cc1ccc(cc1)C(O)CCc2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P05 compound treatment 0.295 0.0409 2.2 2.1982 1.0 1912074 Bionet2_001391 CCNc1nc2ccccc2n1Cc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P06 compound treatment 0.241 -0.0131 -0.7 -0.7036 -1.0 1912075 Bionet2_001392 Cc1ccc(C)n1C(CC(=O)O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P07 compound treatment 0.239 -0.0151 -0.81 -0.8111 -1.0 1912076 Bionet2_001393 CC(C)(C)C(=O)Nc1cccc2[nH]ncc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P08 compound treatment 0.259 0.00491 0.26 0.2637 1.0 1496306 Bionet2_001394 COC(=O)c1oc2ccccc2c1n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P09 compound treatment 0.247 -0.00709 -0.38 -0.3812 -1.0 1113467 Bionet2_001395 FC(F)(F)C(=O)Nc1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P10 compound treatment 0.263 0.00891 0.48 0.4786 1.0 1912077 Bionet2_001396 Cc1cc2ncc(cn2n1)C(=O)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P11 compound treatment 0.224 -0.0301 -1.62 -1.6172 -1.0 1912078 Bionet2_001397 CCOC(=O)/C=C(\C)/Nc1ccc2cn[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P12 compound treatment 0.347 0.0929 4.99 4.9926 1.0 1912079 Bionet2_001398 CSc1nc2ccccc2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P13 compound treatment 0.262 0.00791 0.42 0.4249 1.0 1912080 Bionet2_001399 CC1=NC(=C(NC(C1)c2ccc(Cl)cc2)C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P14 compound treatment 0.248 -0.00609 -0.33 -0.3275 -1.0 1912081 Bionet2_001400 Cn1nc(c(C#N)c1Oc2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P15 compound treatment 0.347 0.0929 4.99 4.9926 1.0 1156874 Bionet2_001401 COc1ccc(cc1OC)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P16 compound treatment 0.256 0.00191 0.1 0.1024 1.0 1912082 Bionet2_001402 Cc1nc(C)c(I)c(Oc2ccc(C#N)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P17 compound treatment 0.243 -0.0111 -0.6 -0.5962 -1.0 1912083 Bionet2_001403 COc1nc(C)c(Br)c(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P18 compound treatment 0.284 0.0299 1.61 1.6071 1.0 1912084 Bionet2_001404 c1cnn(c1)c2cncc(n2)n3cccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P19 compound treatment 0.232 -0.0221 -1.19 -1.1873 -1.0 1632632 Bionet2_001405 COc1cccc(c1)C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P20 compound treatment 0.231 -0.0231 -1.24 -1.241 -1.0 1912085 Bionet2_001406 NC(CCO)c1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P21 compound treatment 0.276 0.0219 1.18 1.1772 1.0 1679649 Bionet2_001407 CCOc1ncccc1C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P22 compound treatment 0.544 0.29 15.58 15.579 1.0 1912086 Bionet2_001408 FC(F)(F)c1ccccc1/C=C/2\SC(=S)NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P23 mock treatment 0.236 -0.0181 -0.97 -0.9723 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1367 P24 mock treatment 0.24 -0.0141 -0.76 -0.7574 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A01 compound treatment 0.309 0.0607 3.26 3.2605 1.0 1912087 Bionet2_001409 Cc1ccc(CN2C(=O)C3CCCN3c4ncccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A02 compound treatment 0.222 -0.0263 -1.41 -1.4147 -1.0 1677061 Bionet2_001410 CSc1c(nc2ccccc2c1C(=O)O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A03 compound treatment 0.256 0.00767 0.41 0.4124 1.0 1912088 Bionet2_001411 CCOC(=O)c1cnc2n(CC)nc(C)c2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A04 compound treatment 0.273 0.0247 1.33 1.3259 1.0 1216525 Bionet2_001412 CC1CN(Cc2c(nc3ccc(Cl)cn23)c4ccccc4)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A05 compound treatment 0.24 -0.00833 -0.45 -0.4474 -1.0 1912089 Bionet2_001413 Clc1ccc(Cn2cccn2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A06 compound treatment 0.232 -0.0163 -0.88 -0.8773 -1.0 1912090 Bionet2_001414 Cc1cccnc1NC(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A07 compound treatment 0.241 -0.00733 -0.39 -0.3937 -1.0 1912091 Bionet2_001415 Cc1nccn1Cc2ccc(Cl)nc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A08 compound treatment 0.234 -0.0143 -0.77 -0.7699 -1.0 1912092 Bionet2_001416 OC(=O)C(NC(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A09 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912093 Bionet2_001417 Cc1ccc(CN2C(=O)C3CCCN3c4ccc(C#N)cc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A10 compound treatment 0.262 0.0137 0.73 0.7348 1.0 1912094 Bionet2_001418 Nc1c(Cl)cc(Cl)cc1C(=O)NO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A11 compound treatment 0.314 0.0657 3.53 3.5292 1.0 1912095 Bionet2_001419 O=C(NCCc1ccccn1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A12 compound treatment 0.233 -0.0153 -0.82 -0.8236 -1.0 1912096 Bionet2_001420 O=C(c1ccccc1)c2ccccc2n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A13 compound treatment 0.239 -0.00933 -0.5 -0.5012 -1.0 1912097 Bionet2_001421 O=S1(=O)CCN(CC1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A14 compound treatment 0.247 -0.00133 -0.07 -0.0713 -1.0 1912098 Bionet2_001422 Cc1ccc(/C=C/C(=O)CCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A15 compound treatment 0.25 0.00167 0.09 0.09 1.0 1912099 Bionet2_001423 COc1ccccc1/C=C(\C#N)/c2ccc(cc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A16 compound treatment 0.452 0.204 10.95 10.945 1.0 1912100 Bionet2_001424 c1cc(on1)c2ccc(cc2)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A17 compound treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1912101 Bionet2_001425 ClCCCS(=O)(=O)NC1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A18 compound treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1450595 Bionet2_001426 CC1(C)CC(=O)C2=C(C1)OC(=O)CC2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A19 compound treatment 0.501 0.253 13.58 13.5782 1.0 1912102 Bionet2_001427 Clc1ccc(cc1Cl)c2nnc3CCCCn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A20 compound treatment 0.369 0.121 6.48 6.4848 1.0 1912103 Bionet2_001428 N#Cc1c(/C=C/Nc2ccccc2)onc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A21 compound treatment 0.266 0.0177 0.95 0.9498 1.0 1912104 Bionet2_001429 Clc1ccc(NC(=O)OCc2ccc(Cl)nc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A22 compound treatment 0.363 0.115 6.16 6.1623 1.0 1912105 Bionet2_001430 FC(F)(F)c1ccc(cc1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A23 mock treatment 0.255 0.00667 0.36 0.3586 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 A24 mock treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B01 compound treatment 0.25 0.00167 0.09 0.09 1.0 1912106 Bionet2_001431 FC(F)(F)c1cccc(Oc2cnc3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B02 compound treatment 0.258 0.00967 0.52 0.5199 1.0 1912107 Bionet2_001432 FC(F)(F)c1cc(Oc2ccccc2)nc(n1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B03 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1639127 Bionet2_001433 CC(=O)Nc1cccc(Oc2cnc3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B04 compound treatment 0.267 0.0187 1.0 1.0035 1.0 1912108 Bionet2_001434 Cc1nc(N)nc(SCc2ccccc2Cl)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B05 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1912109 Bionet2_001435 Clc1ccc(cc1Cl)c2ccnc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B06 compound treatment 0.289 0.0407 2.19 2.1857 1.0 1912110 Bionet2_001436 CSc1cccc(c1)n2cc3ccsc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B07 compound treatment 0.247 -0.00133 -0.07 -0.0713 -1.0 1912111 Bionet2_001437 Cc1ccc(cc1)N2CS(=O)(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B08 compound treatment 0.25 0.00167 0.09 0.09 1.0 1146919 Bionet2_001438 COC(=O)c1c[nH]c(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B09 compound treatment 0.267 0.0187 1.0 1.0035 1.0 1404716 Bionet2_001439 N#Cc1cnn2c(ccnc12)c3ccc(Oc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B10 mock treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B11 compound treatment 0.331 0.0827 4.44 4.4427 1.0 1912112 Bionet2_001440 Clc1ccc(CSc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B12 mock treatment 0.255 0.00667 0.36 0.3586 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B13 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912113 Bionet2_001441 NC(=C(C#N)C#N)COc1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B14 mock treatment 0.258 0.00967 0.52 0.5199 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B15 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1912114 Bionet2_001442 FC(F)(F)c1cccc(Nc2ncn[nH]2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B16 mock treatment 0.254 0.00567 0.3 0.3049 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B17 compound treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1585179 Bionet2_001443 Cc1nc2c(C)cccn2c1C(=O)Nc3ccc(F)cc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B18 mock treatment 0.251 0.00267 0.14 0.1437 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B19 compound treatment 0.273 0.0247 1.33 1.3259 1.0 1912115 Bionet2_001444 FC(F)(F)c1cccc(N/C=C/2\OC(=O)c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B20 mock treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B21 compound treatment 0.473 0.225 12.07 12.0735 1.0 1912116 Bionet2_001445 N#Cc1c(Sc2ccccc2)nc3sccn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B22 mock treatment 0.254 0.00567 0.3 0.3049 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B23 mock treatment 0.241 -0.00733 -0.39 -0.3937 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 B24 mock treatment 0.237 -0.0113 -0.61 -0.6086 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C01 compound treatment 0.236 -0.0123 -0.66 -0.6624 -1.0 1912117 Bionet2_001446 CC(C)(C)n1ncc(C(=O)O)c1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C02 compound treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1912118 Bionet2_001447 Cc1ccc(cc1)c2c(C(=O)O)c3ccccc3[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C03 compound treatment 0.424 0.176 9.44 9.4403 1.0 1912119 Bionet2_001448 CS(=O)(=O)N1CC2CCCN2c3ccc(cc13)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C04 compound treatment 0.323 0.0747 4.01 4.0128 1.0 1912120 Bionet2_001449 Cn1nc(c2cc(NC(=O)OCC(C)(C)C)sc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C05 compound treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1912121 Bionet2_001450 Clc1ccc(CN2CCCCC2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C06 compound treatment 0.238 -0.0103 -0.55 -0.5549 -1.0 1912122 Bionet2_001451 Cc1nc(cc(c1C#N)C(F)(F)F)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C07 compound treatment 0.345 0.0967 5.2 5.1951 1.0 1912123 Bionet2_001452 Clc1ccc(COc2ccc(C#N)cc2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C08 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1379026 Bionet2_001453 CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C09 compound treatment 0.27 0.0217 1.16 1.1647 1.0 1912124 Bionet2_001454 Cc1cccc(C)c1N2CCN(Cc3ccc(Cl)nc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C10 compound treatment 0.241 -0.00733 -0.39 -0.3937 -1.0 1912125 Bionet2_001455 CC1CN(CC(C)O1)C(=O)Cn2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C11 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1912126 Bionet2_001456 CC(=O)N1CCN(Cc2cnc(Cl)s2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C12 compound treatment 0.333 0.0847 4.55 4.5502 1.0 1912127 Bionet2_001457 CN1CCN(CC1)c2ccc(cc2NO)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C13 compound treatment 0.247 -0.00133 -0.07 -0.0713 -1.0 1912128 Bionet2_001458 O=S1(=O)CCN(CC1)C2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C14 compound treatment 0.273 0.0247 1.33 1.3259 1.0 1912129 Bionet2_001459 COc1ccc(/C=C/C(=O)CCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C15 compound treatment 0.301 0.0527 2.83 2.8306 1.0 1912130 Bionet2_001460 Clc1ccc(cc1)c2nc3c4ccsc4ncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C16 compound treatment 0.243 -0.00533 -0.29 -0.2862 -1.0 1912131 Bionet2_001461 NC(=O)c1ccccc1n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C17 compound treatment 0.256 0.00767 0.41 0.4124 1.0 1912132 Bionet2_001462 N#CCSc1ncccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C18 compound treatment 0.484 0.236 12.66 12.6646 1.0 1589683 Bionet2_001463 O=C(c1ccc(cc1)n2ccnc2)c3ccc(cc3)n4ccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C19 compound treatment 0.247 -0.00133 -0.07 -0.0713 -1.0 1912133 Bionet2_001464 OCC1CC2CCCC[N+]2(Cc3ccccc3)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C20 compound treatment 0.279 0.0307 1.65 1.6484 1.0 1912134 Bionet2_001465 N#Cc1c(/C=C/NCc2ccccc2)onc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C21 compound treatment 0.38 0.132 7.08 7.0759 1.0 1912135 Bionet2_001466 Clc1ccc(cc1)c2[nH]nc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C22 compound treatment 0.359 0.111 5.95 5.9474 1.0 1912136 Bionet2_001467 FC(F)(F)Oc1ccc(cc1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C23 mock treatment 0.267 0.0187 1.0 1.0035 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 C24 mock treatment 0.239 -0.00933 -0.5 -0.5012 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D01 compound treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1912137 Bionet2_001468 Clc1cccc(Oc2cnc3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D02 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1912138 Bionet2_001469 FC(F)(F)c1cc(NCC=C)nc(n1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D03 compound treatment 0.295 0.0467 2.51 2.5082 1.0 1522211 Bionet2_001470 CN1CCN(CC1)c2ccc(cc2)c3ccno3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D04 compound treatment 0.296 0.0477 2.56 2.5619 1.0 1912139 Bionet2_001471 CCOC(=O)Cc1nnc([nH]1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D05 compound treatment 0.285 0.0367 1.97 1.9708 1.0 1146432 Bionet2_001472 Nc1c(cnc2ncnn12)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D06 compound treatment 0.466 0.218 11.7 11.6973 1.0 1280062 Bionet2_001473 Nc1nccc(n1)c2ccc(Oc3ccc(Cl)cc3)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D07 compound treatment 0.258 0.00967 0.52 0.5199 1.0 1912140 Bionet2_001474 Brc1ccc(cc1)N2CS(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D08 compound treatment 0.392 0.144 7.72 7.7207 1.0 1912141 Bionet2_001475 O/N=C/C(C(=O)Nc1ccccc1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D09 compound treatment 0.442 0.194 10.41 10.4076 1.0 1209138 Bionet2_001476 Cc1ccc(cc1)S(=O)(=O)c2c[nH]nc2c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D10 mock treatment 0.243 -0.00533 -0.29 -0.2862 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D11 compound treatment 0.262 0.0137 0.73 0.7348 1.0 1206973 Bionet2_001477 Cc1ccccc1CS(=O)(=O)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D12 mock treatment 0.237 -0.0113 -0.61 -0.6086 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D13 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1912142 Bionet2_001478 NC(=C(C#N)C#N)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D14 mock treatment 0.251 0.00267 0.14 0.1437 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D15 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1373692 Bionet2_001479 Cc1nc(nc2CCCc21)S(=O)(=O)Cc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D16 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D17 compound treatment 0.339 0.0907 4.87 4.8726 1.0 1705439 Bionet2_001480 CCOC(=O)c1c(nc2ccccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D18 mock treatment 0.259 0.0107 0.57 0.5736 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D19 compound treatment 0.343 0.0947 5.09 5.0876 1.0 1912143 Bionet2_001481 COc1ccc(N/C=C/2\OC(=O)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D20 mock treatment 0.246 -0.00233 -0.12 -0.125 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D21 compound treatment 0.31 0.0617 3.31 3.3142 1.0 1912144 Bionet2_001482 N#Cc1c(SCc2ccccc2)nc3sccn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D22 mock treatment 0.259 0.0107 0.57 0.5736 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D23 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 D24 mock treatment 0.243 -0.00533 -0.29 -0.2862 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E01 compound treatment 0.473 0.225 12.07 12.0735 1.0 1912145 Bionet2_001483 CSC1=NC(=O)/C(=C/c2ccccc2C(F)(F)F)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E02 compound treatment 0.437 0.189 10.14 10.1389 1.0 1912146 Bionet2_001484 COC(=O)C1CC(=NO1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E03 compound treatment 0.334 0.0857 4.6 4.6039 1.0 1912147 Bionet2_001485 COc1ccc(OC)c2nc3CCCCCc3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E04 compound treatment 0.25 0.00167 0.09 0.09 1.0 1912148 Bionet2_001486 COC(C(=O)O)C(=O)Nc1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E05 compound treatment 0.259 0.0107 0.57 0.5736 1.0 1912149 Bionet2_001487 CCOC(=O)C1CCN(Cc2ccc(Cl)nc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E06 compound treatment 0.235 -0.0133 -0.72 -0.7161 -1.0 1912150 Bionet2_001488 CC1(C)Nc2ccccc2OP1(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E07 compound treatment 0.256 0.00767 0.41 0.4124 1.0 1912151 Bionet2_001489 NC(CCO)c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E08 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1213957 Bionet2_001490 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E09 compound treatment 0.477 0.229 12.29 12.2885 1.0 1912152 Bionet2_001491 Clc1ccc(COc2cccc3cccnc23)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E10 compound treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1912153 Bionet2_001492 CC(C(=O)Nc1ccccc1C)n2c(nc3ccccc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E11 compound treatment 0.293 0.0447 2.4 2.4007 1.0 1912154 Bionet2_001493 COC(=O)c1ccccc1Oc2ccc(NC(=O)c3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E12 compound treatment 0.258 0.00967 0.52 0.5199 1.0 1912155 Bionet2_001494 COC(=O)c1ccccc1NC(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E13 compound treatment 0.263 0.0147 0.79 0.7885 1.0 1912156 Bionet2_001495 CCc1nc2cc(CC(=O)O)ccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E14 compound treatment 0.321 0.0727 3.91 3.9053 1.0 1912157 Bionet2_001496 CNC1=C(C(=O)C(O1)c2ccccc2)c3ccc(cc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E15 compound treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1912158 Bionet2_001497 Cc1ccc(C)n1C(CC(=O)O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E16 compound treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1912159 Bionet2_001498 C[n+]1ccn(c1)c2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E17 compound treatment 0.27 0.0217 1.16 1.1647 1.0 1912160 Bionet2_001499 CN1CCC(CC1)NS(=O)(=O)c2ccc(I)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E18 compound treatment 0.416 0.168 9.01 9.0104 1.0 1560406 Bionet2_001500 OC(c1ccc(cc1)n2ccnc2)c3ccc(cc3)n4ccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E19 compound treatment 0.271 0.0227 1.22 1.2184 1.0 1912161 Bionet2_001501 CSC1=NC(=CC(C)(C)N1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E20 compound treatment 0.308 0.0597 3.21 3.2068 1.0 1912162 Bionet2_001502 CN(C)/C=C/c1onc(c1C#N)c2c(F)cccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E21 compound treatment 0.507 0.259 13.9 13.9006 1.0 1912163 Bionet2_001503 Cc1ccc(cc1)c2[nH]nc3CCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E22 compound treatment 0.428 0.18 9.66 9.6553 1.0 1912164 Bionet2_001504 Fc1ccc(N/C=C\2/CCN(C2=O)c3ccc(Cl)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E23 mock treatment 0.259 0.0107 0.57 0.5736 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 E24 mock treatment 0.249 6.74E-4 0.04 0.0362 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F01 compound treatment 0.307 0.0587 3.15 3.153 1.0 1912165 Bionet2_001505 Clc1ccccc1Sc2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F02 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1318723 Bionet2_001506 OCC1(CO)COc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F03 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1912166 Bionet2_001507 Oc1ncn(n1)c2cccc(Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F04 compound treatment 0.369 0.121 6.48 6.4848 1.0 1912167 Bionet2_001508 Oc1ccc2cc(NC(=O)c3cccc(c3)C(F)(F)F)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F05 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1912168 Bionet2_001509 Cc1n[nH]c(C)c1Cc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F06 compound treatment 0.251 0.00267 0.14 0.1437 1.0 1912169 Bionet2_001510 Fc1cccc(n1)n2ccc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F07 compound treatment 0.34 0.0917 4.93 4.9264 1.0 1912170 Bionet2_001511 Cc1ccc(cc1)N2CS(=O)/C(=C/Nc3ccc(Cl)cc3)/C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F08 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1729716 Bionet2_001512 Ic1ncccc1OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F09 compound treatment 0.289 0.0407 2.19 2.1857 1.0 1316209 Bionet2_001513 Cc1ccc2oc3ncc(cc3c(=O)c2c1)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F10 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F11 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1507791 Bionet2_001514 CC(Oc1ccccc1)c2ccnn2S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F12 mock treatment 0.255 0.00667 0.36 0.3586 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F13 compound treatment 0.318 0.0697 3.74 3.7441 1.0 1590565 Bionet2_001515 COc1ccc(cc1)C2=C(C#N)C(=O)OC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F14 mock treatment 0.253 0.00467 0.25 0.2512 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F15 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1151986 Bionet2_001516 COc1ccc(Nc2ncn[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F16 mock treatment 0.25 0.00167 0.09 0.09 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F17 compound treatment 0.484 0.236 12.66 12.6646 1.0 1912171 Bionet2_001517 O=C(c1cnc(s1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F18 mock treatment 0.235 -0.0133 -0.72 -0.7161 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F19 compound treatment 0.298 0.0497 2.67 2.6694 1.0 1912172 Bionet2_001518 Clc1ccc(/C=C/2\OC(=O)c3ccccc23)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F20 mock treatment 0.249 6.74E-4 0.04 0.0362 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F21 compound treatment 0.492 0.244 13.09 13.0945 1.0 1331082 Bionet2_001519 Cc1oc(=O)c(NC(=O)c2ccccc2)cc1C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F22 mock treatment 0.258 0.00967 0.52 0.5199 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F23 mock treatment 0.251 0.00267 0.14 0.1437 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 F24 mock treatment 0.23 -0.0183 -0.98 -0.9848 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G01 compound treatment 0.265 0.0167 0.9 0.896 1.0 1912173 Bionet2_001520 Cc1ccc(CNC(=O)Cc2noc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G02 compound treatment 0.341 0.0927 4.98 4.9801 1.0 1305766 Bionet2_001521 COc1ccc2oc(C#N)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G03 compound treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1912174 Bionet2_001522 OCC(N1Cc2ccccc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G04 compound treatment 0.409 0.161 8.63 8.6343 1.0 1912175 Bionet2_001523 Cn1cnnc1SCC(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G05 compound treatment 0.27 0.0217 1.16 1.1647 1.0 1010579 Bionet2_001524 CCN1C(=O)Cc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G06 compound treatment 0.293 0.0447 2.4 2.4007 1.0 1912176 Bionet2_001525 Cc1ccc(cc1)S(=O)(=O)N2CCC(=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G07 compound treatment 0.435 0.187 10.03 10.0315 1.0 1912177 Bionet2_001526 COc1ccc2[nH]cc(/C=C(/C#N)\S(=O)(=O)c3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G08 compound treatment 0.464 0.216 11.59 11.5899 1.0 1912178 Bionet2_001527 Cc1cc(C)c(c(=O)[nH]1)S(=O)(=O)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G09 compound treatment 0.45 0.202 10.84 10.8375 1.0 1912179 Bionet2_001528 Clc1ccc(CSc2nc3ccccc3s2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G10 compound treatment 0.243 -0.00533 -0.29 -0.2862 -1.0 1912180 Bionet2_001529 OCCn1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G11 compound treatment 0.395 0.147 7.88 7.8819 1.0 1912181 Bionet2_001530 CSc1nc2nc(ccn2n1)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G12 compound treatment 0.406 0.158 8.47 8.4731 1.0 1912182 Bionet2_001531 C/C(=N\O)/c1sc(nc1C)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G13 compound treatment 0.29 0.0417 2.24 2.2395 1.0 1912183 Bionet2_001532 Ic1ccc(cc1)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G14 compound treatment 0.392 0.144 7.72 7.7207 1.0 1912184 Bionet2_001533 Nc1ccc(Sc2ccccc2)c(C#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G15 compound treatment 0.277 0.0287 1.54 1.5409 1.0 1912185 Bionet2_001534 COC(=O)Cc1ccc2OCC(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G16 compound treatment 0.371 0.123 6.59 6.5922 1.0 1912186 Bionet2_001535 N#Cc1ccc(cc1)n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G17 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1912187 Bionet2_001536 OCCC(N1CCS(=O)(=O)CC1)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G18 compound treatment 0.263 0.0147 0.79 0.7885 1.0 1007590 Bionet2_001537 C=CCN(CC=C)c1nnn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G19 compound treatment 0.256 0.00767 0.41 0.4124 1.0 1608009 Bionet2_001538 CN(C)S(=O)(=O)N1CCN(C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G20 compound treatment 0.321 0.0727 3.91 3.9053 1.0 1912188 Bionet2_001539 Nc1nc(SC/C=C/c2ccccc2)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G21 compound treatment 0.29 0.0417 2.24 2.2395 1.0 1408491 Bionet2_001540 Clc1ccc(cc1)C(=O)c2cnc3ccccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G22 compound treatment 0.295 0.0467 2.51 2.5082 1.0 1912189 Bionet2_001541 CSc1nsc(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G23 mock treatment 0.253 0.00467 0.25 0.2512 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 G24 mock treatment 0.24 -0.00833 -0.45 -0.4474 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H01 compound treatment 0.384 0.136 7.29 7.2908 1.0 1912190 Bionet2_001542 Cc1ccc(Sc2cnc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H02 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1205544 Bionet2_001543 OCC1(CO)CSc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H03 compound treatment 0.283 0.0347 1.86 1.8633 1.0 1912191 Bionet2_001544 Oc1ncn(n1)c2ncc(cc2Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H04 compound treatment 0.297 0.0487 2.62 2.6156 1.0 1340421 Bionet2_001545 Nc1c(cnn1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H05 compound treatment 0.351 0.103 5.52 5.5175 1.0 1912192 Bionet2_001546 Cc1nn(c(C)c1Cc2ccc(O)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H06 compound treatment 0.29 0.0417 2.24 2.2395 1.0 1912193 Bionet2_001547 Nc1nn(cc1c2ccc(Cl)cc2)c3cccc(F)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H07 compound treatment 0.246 -0.00233 -0.12 -0.125 -1.0 1912194 Bionet2_001548 FC(F)(F)c1ccc(cc1)N2CS(=O)(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H08 compound treatment 0.257 0.00867 0.47 0.4661 1.0 1550622 Bionet2_001549 CCNC(=O)Oc1cccnc1I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H09 compound treatment 0.254 0.00567 0.3 0.3049 1.0 1444759 Bionet2_001550 Clc1ccc(cc1)c2n[nH]cc2N3C=CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H10 mock treatment 0.26 0.0117 0.63 0.6273 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H11 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1122302 Bionet2_001551 CC(Oc1ccccc1)c2ccnc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H12 mock treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H13 compound treatment 0.43 0.182 9.76 9.7628 1.0 1912195 Bionet2_001552 Clc1nc2sccn2c1/C=N/Cc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H14 mock treatment 0.241 -0.00733 -0.39 -0.3937 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H15 compound treatment 0.521 0.273 14.65 14.6529 1.0 1912196 Bionet2_001553 COC/1=CC(=O)S\C1=C/Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H16 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H17 compound treatment 0.464 0.216 11.59 11.5899 1.0 1492156 Bionet2_001554 CC(C)(C)C(=O)c1cnc(Nc2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H18 mock treatment 0.258 0.00967 0.52 0.5199 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H19 compound treatment 0.422 0.174 9.33 9.3329 1.0 1912197 Bionet2_001555 CSc1cccc(N/C=C/2\OC(=O)c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H20 mock treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H21 compound treatment 0.259 0.0107 0.57 0.5736 1.0 1912198 Bionet2_001556 COc1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H22 mock treatment 0.256 0.00767 0.41 0.4124 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H23 mock treatment 0.256 0.00767 0.41 0.4124 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 H24 mock treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I01 compound treatment 0.287 0.0387 2.08 2.0783 1.0 1912199 Bionet2_001557 Clc1cccc(CNC(=O)Cc2noc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I02 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1912200 Bionet2_001558 Clc1ccc(cc1)C(=O)Cn2cncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I03 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1912201 Bionet2_001559 COC(=O)CN1Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I04 compound treatment 0.272 0.0237 1.27 1.2722 1.0 1912202 Bionet2_001560 Clc1ccc(cc1)S(=O)(=O)N2CCC(=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I05 compound treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1912203 Bionet2_001561 COc1ccc(cc1F)c2nc3ncnn3cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I06 compound treatment 0.278 0.0297 1.59 1.5946 1.0 1912204 Bionet2_001562 O=C(OCC#N)/C=C\c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I07 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1912205 Bionet2_001563 COc1ccc(/C=N/O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I08 compound treatment 0.324 0.0757 4.07 4.0666 1.0 1912206 Bionet2_001564 Cc1cc(C)c(c(=O)[nH]1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I09 compound treatment 0.347 0.0987 5.3 5.3025 1.0 1912207 Bionet2_001565 Fc1cccc(Cl)c1CN2C(=O)C3CCCN3c4ccc(C#N)cc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I10 compound treatment 0.483 0.235 12.61 12.6109 1.0 1912208 Bionet2_001566 Cc1ccc(cc1)C(=O)CCc2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I11 compound treatment 0.247 -0.00133 -0.07 -0.0713 -1.0 1912209 Bionet2_001567 Cc1nc2cc(CC(=O)O)ccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I12 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1912210 Bionet2_001568 Cc1cc(O)nc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I13 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1912211 Bionet2_001569 OC(=O)C1CCN(CC1)C(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I14 compound treatment 0.296 0.0477 2.56 2.5619 1.0 1912212 Bionet2_001570 Brc1snnc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I15 compound treatment 0.312 0.0637 3.42 3.4217 1.0 1912213 Bionet2_001571 Nc1[nH]ncc1c2ccc(cc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I16 compound treatment 0.384 0.136 7.29 7.2908 1.0 1912214 Bionet2_001572 O/N=C/NC(=O)c1ccc(cc1)n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I17 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912215 Bionet2_001573 Cn1cc(c2ccccc2C(=O)O)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I18 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912216 Bionet2_001574 CC(C)(C)c1ccn(CC(=O)c2ccc(Cl)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I19 compound treatment 0.284 0.0357 1.92 1.917 1.0 1912217 Bionet2_001575 N#Cc1cnc(Nc2ccccc2)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I20 compound treatment 0.34 0.0917 4.93 4.9264 1.0 1912218 Bionet2_001576 COc1ccccc1N/C=C(\C#N)/c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I21 compound treatment 0.301 0.0527 2.83 2.8306 1.0 1912219 Bionet2_001577 COc1cc(/N=C\2/NCCS2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I22 compound treatment 0.266 0.0177 0.95 0.9498 1.0 1912220 Bionet2_001578 CN(C)c1sc(C#N)cc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I23 mock treatment 0.254 0.00567 0.3 0.3049 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 I24 mock treatment 0.255 0.00667 0.36 0.3586 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J01 compound treatment 0.291 0.0427 2.29 2.2932 1.0 1912221 Bionet2_001579 Clc1ccccc1Oc2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J02 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1156150 Bionet2_001580 O=C1c2ccccc2OCC31COC(OC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J03 compound treatment 0.277 0.0287 1.54 1.5409 1.0 1912222 Bionet2_001581 Brc1ccc(cc1)c2ccnc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J04 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912223 Bionet2_001582 Nc1c(cnn1c2ccc3c(cc(nc3n2)C(F)(F)F)C(F)(F)F)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J05 compound treatment 0.282 0.0337 1.81 1.8096 1.0 1912224 Bionet2_001583 CN1CCN(CC1)c2ccc(cc2)c3ccnn3C(=O)Nc4cccc(c4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J06 compound treatment 0.466 0.218 11.7 11.6973 1.0 1654476 Bionet2_001584 COc1ccc(cc1)c2ccn(n2)c3cccc(F)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J07 compound treatment 0.28 0.0317 1.7 1.7021 1.0 1493311 Bionet2_001585 Cc1ccc(cc1)S(=O)(=O)N2CCSc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J08 mock treatment 0.252 0.00367 0.2 0.1974 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J09 compound treatment 0.488 0.24 12.88 12.8796 1.0 1912225 Bionet2_001586 Clc1cccc(n1)N2CCN(CC2)C(=O)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J10 mock treatment 0.252 0.00367 0.2 0.1974 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J11 compound treatment 0.305 0.0567 3.05 3.0455 1.0 1912226 Bionet2_001587 O/N=C/c1coc2ccc(Cl)cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J12 mock treatment 0.237 -0.0113 -0.61 -0.6086 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J13 compound treatment 0.355 0.107 5.73 5.7324 1.0 1912227 Bionet2_001588 CC(C)/N=C/c1c(Cl)nc2sccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J14 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J15 compound treatment 0.389 0.141 7.56 7.5595 1.0 1912228 Bionet2_001589 ONC(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J16 mock treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J17 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1912229 Bionet2_001590 CNc1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J18 mock treatment 0.252 0.00367 0.2 0.1974 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J19 compound treatment 0.508 0.26 13.95 13.9543 1.0 1912230 Bionet2_001591 O=C1O/C(=C\N2CCN(CC2)c3ccccc3)/c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J20 mock treatment 0.246 -0.00233 -0.12 -0.125 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J21 compound treatment 0.257 0.00867 0.47 0.4661 1.0 1912231 Bionet2_001592 CNc1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J22 mock treatment 0.253 0.00467 0.25 0.2512 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J23 mock treatment 0.249 6.74E-4 0.04 0.0362 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 J24 mock treatment 0.243 -0.00533 -0.29 -0.2862 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K01 compound treatment 0.389 0.141 7.56 7.5595 1.0 1912232 Bionet2_001593 Cc1ccc(CC2SC(=O)NC2=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K02 compound treatment 0.238 -0.0103 -0.55 -0.5549 -1.0 1912233 Bionet2_001594 CN1C(=O)CCC1(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K03 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1088233 Bionet2_001595 O=C1Cc2ccccc2N1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K04 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1912234 Bionet2_001596 OC(CCl)CN1CCN(CC1)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K05 compound treatment 0.299 0.0507 2.72 2.7231 1.0 1716936 Bionet2_001597 O=C(C1COc2ccccc2O1)N3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K06 compound treatment 0.254 0.00567 0.3 0.3049 1.0 1912235 Bionet2_001598 CC(C)(C)C(=O)Nc1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K07 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1912236 Bionet2_001599 Clc1ccc(CNc2nccs2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K08 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1912237 Bionet2_001600 Cc1cc(C)c(c(Cl)n1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K09 compound treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1912238 Bionet2_001601 CCOC(=O)C1CSC2(CCCCC2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K10 compound treatment 0.266 0.0177 0.95 0.9498 1.0 1912239 Bionet2_001602 COc1ccc(/C=N\c2ccc(/C=C\C(=O)O)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K11 compound treatment 0.269 0.0207 1.11 1.111 1.0 1912240 Bionet2_001603 CSc1ccc(cc1)C(N)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K12 compound treatment 0.257 0.00867 0.47 0.4661 1.0 1912241 Bionet2_001604 OCC1(F)CCN(CC1)C(=O)c2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K13 compound treatment 0.268 0.0197 1.06 1.0572 1.0 1912242 Bionet2_001605 CSc1nn2ccc(nc2c1C#N)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K14 compound treatment 0.311 0.0627 3.37 3.368 1.0 1912243 Bionet2_001606 CS(=O)(=O)c1ccc(C(=O)Nc2ccc(cc2)N3CCCCC3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K15 compound treatment 0.557 0.309 16.59 16.5875 1.0 1912244 Bionet2_001607 CSC1=NC(=O)/C(=C\c2cccc3ccccc23)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K16 compound treatment 0.427 0.179 9.6 9.6016 1.0 1912245 Bionet2_001608 Clc1ccc(N/C=C\2/Sc3ccccc3NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K17 compound treatment 0.373 0.125 6.7 6.6997 1.0 1512596 Bionet2_001609 Cc1ccc2oc(c3ccccc3)c(C(=O)O)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K18 compound treatment 0.38 0.132 7.08 7.0759 1.0 1912246 Bionet2_001610 N#C/C(=C/Nc1ccccc1)/c2ccsc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K19 compound treatment 0.398 0.15 8.04 8.0432 1.0 1526036 Bionet2_001611 COc1ccc(CNc2ncc(C#N)cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K20 compound treatment 0.513 0.265 14.22 14.223 1.0 1912247 Bionet2_001612 COc1cccc(N/C=C(\C#N)/c2ccc(Cl)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K21 compound treatment 0.313 0.0647 3.48 3.4754 1.0 1912248 Bionet2_001613 COC(=O)c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K22 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1382157 Bionet2_001614 Cc1cc(C)c(C(=O)O)c(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K23 mock treatment 0.265 0.0167 0.9 0.896 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 K24 mock treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L01 compound treatment 0.353 0.105 5.62 5.625 1.0 1223726 Bionet2_001615 Cc1ccc(cc1)S(=O)(=O)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L02 compound treatment 0.262 0.0137 0.73 0.7348 1.0 1912249 Bionet2_001616 O=C1c2ccccc2SCC31COC(OC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L03 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912250 Bionet2_001617 c1coc(c1)c2ccnc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L04 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1912251 Bionet2_001618 COc1ccc(cc1)n2cc3ccsc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L05 compound treatment 0.265 0.0167 0.9 0.896 1.0 1912252 Bionet2_001619 Clc1ccc(cc1)N2CSCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L06 compound treatment 0.419 0.171 9.17 9.1717 1.0 1912253 Bionet2_001620 Nc1c(cnn1c2ccccc2)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L07 compound treatment 0.241 -0.00733 -0.39 -0.3937 -1.0 1912254 Bionet2_001621 Clc1ccc(cc1Cl)N2CS(=O)(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L08 mock treatment 0.246 -0.00233 -0.12 -0.125 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L09 compound treatment 0.293 0.0447 2.4 2.4007 1.0 1594710 Bionet2_001622 C1CN(CCO1)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L10 mock treatment 0.253 0.00467 0.25 0.2512 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L11 compound treatment 0.285 0.0367 1.97 1.9708 1.0 1499205 Bionet2_001623 CCN(CC)C(=O)c1cc2c(=O)c3cc(Cl)ccc3oc2nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L12 mock treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L13 compound treatment 0.36 0.112 6.0 6.0011 1.0 1912255 Bionet2_001624 C/N=C/c1c(Cl)nc2sccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L14 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L15 compound treatment 0.492 0.244 13.09 13.0945 1.0 1912256 Bionet2_001625 Oc1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L16 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L17 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1912257 Bionet2_001626 CC(C)Oc1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L18 mock treatment 0.259 0.0107 0.57 0.5736 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L19 compound treatment 0.496 0.248 13.31 13.3095 1.0 1912258 Bionet2_001627 FC(F)(F)c1cccc(CSc2ccc3nnc(Cl)n3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L20 mock treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L21 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912259 Bionet2_001628 CN(C)c1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L22 mock treatment 0.254 0.00567 0.3 0.3049 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L23 mock treatment 0.254 0.00567 0.3 0.3049 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 L24 mock treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M01 compound treatment 0.277 0.0287 1.54 1.5409 1.0 1912260 Bionet2_001629 N#Cc1ccc(nc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M02 compound treatment 0.431 0.183 9.82 9.8165 1.0 1912261 Bionet2_001630 c1cn(cn1)c2ccc(cc2)c3csnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M03 compound treatment 0.248 -3.26E-4 -0.02 -0.0175 -1.0 1912262 Bionet2_001631 Clc1ccc(CN2CCOCC2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M04 compound treatment 0.328 0.0797 4.28 4.2815 1.0 1912263 Bionet2_001632 CSc1ccccc1C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M05 compound treatment 0.288 0.0397 2.13 2.132 1.0 1912264 Bionet2_001633 Clc1ccc(Cn2ccc3ccccc23)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M06 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1912265 Bionet2_001634 COc1cccc(c1)C(=O)NC(Cc2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M07 compound treatment 0.285 0.0367 1.97 1.9708 1.0 1912266 Bionet2_001635 COc1ccc2[nH]cc(/C=C\3/C(=O)N(C)C(=O)c4ccccc34)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M08 compound treatment 0.261 0.0127 0.68 0.6811 1.0 1912267 Bionet2_001636 OC(=O)CCC(=O)/C=C/c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M09 compound treatment 0.334 0.0857 4.6 4.6039 1.0 1912268 Bionet2_001637 CCOC(=O)C(C)Oc1ccc(OCc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M10 compound treatment 0.276 0.0277 1.49 1.4871 1.0 1912269 Bionet2_001638 OC(=O)/C=C/c1ccc2CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M11 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1912270 Bionet2_001639 CC(C)c1ccc(cc1)C(CC(=O)O)NC(=O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M12 compound treatment 0.269 0.0207 1.11 1.111 1.0 1912271 Bionet2_001640 O=c1[nH]c(nc2ccsc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M13 compound treatment 0.351 0.103 5.52 5.5175 1.0 1912272 Bionet2_001641 FC(F)(F)c1ccc2N3CCCCC3C(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M14 compound treatment 0.383 0.135 7.24 7.2371 1.0 1912273 Bionet2_001642 OCc1cc(no1)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M15 compound treatment 0.408 0.16 8.58 8.5805 1.0 1912274 Bionet2_001643 BrCc1ccc(cc1)c2noc(n2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M16 compound treatment 0.484 0.236 12.66 12.6646 1.0 1912275 Bionet2_001644 Clc1ccccc1N/C=C\2/Sc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M17 compound treatment 0.325 0.0767 4.12 4.1203 1.0 1591873 Bionet2_001645 Nc1nn(cc1c2cccs2)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M18 compound treatment 0.492 0.244 13.09 13.0945 1.0 1912276 Bionet2_001646 COc1ccc(N/C=C(/C#N)\c2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M19 compound treatment 0.274 0.0257 1.38 1.3797 1.0 1613921 Bionet2_001647 Fc1cccc(c1C#N)C(C#N)(N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M20 compound treatment 0.489 0.241 12.93 12.9333 1.0 1912277 Bionet2_001648 COc1ccc(N/C=C(\C#N)/c2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M21 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1736316 Bionet2_001649 OCC1CN(Cc2ccccc2)C(O1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M22 compound treatment 0.28 0.0317 1.7 1.7021 1.0 1912278 Bionet2_001650 FC(F)(F)c1nc2oc3ccccc3c(=O)c2cc1C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M23 mock treatment 0.262 0.0137 0.73 0.7348 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 M24 mock treatment 0.256 0.00767 0.41 0.4124 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N01 compound treatment 0.284 0.0357 1.92 1.917 1.0 1912279 Bionet2_001651 CNC(=O)CSc1cnc2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N02 compound treatment 0.254 0.00567 0.3 0.3049 1.0 1275031 Bionet2_001652 C=CCSc1nc2ccsc2c(=O)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N03 compound treatment 0.374 0.126 6.75 6.7535 1.0 1312778 Bionet2_001653 Nc1c(cnc2ncnn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N04 compound treatment 0.286 0.0377 2.02 2.0245 1.0 1912280 Bionet2_001654 FC(F)(F)Oc1ccc(cc1)n2cc3ccsc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N05 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1732552 Bionet2_001655 COc1ccc(cc1)N2CS(=O)(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N06 compound treatment 0.267 0.0187 1.0 1.0035 1.0 1653899 Bionet2_001656 COC(=O)Nc1cn(Cc2cccnc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N07 compound treatment 0.293 0.0447 2.4 2.4007 1.0 1146806 Bionet2_001657 Cc1nc2oc3ccccc3c(=O)c2cc1C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N08 mock treatment 0.238 -0.0103 -0.55 -0.5549 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N09 compound treatment 0.426 0.178 9.55 9.5478 1.0 1134723 Bionet2_001658 C1CN(CCN1c2ccccc2)c3cnc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N10 mock treatment 0.237 -0.0113 -0.61 -0.6086 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N11 compound treatment 0.275 0.0267 1.43 1.4334 1.0 1912281 Bionet2_001659 NC(=C(C#N)C#N)CSc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N12 mock treatment 0.237 -0.0113 -0.61 -0.6086 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N13 compound treatment 0.375 0.127 6.81 6.8072 1.0 1912282 Bionet2_001660 FC(F)(F)Oc1ccc(/N=C/c2c(Cl)nc3sccn23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N14 mock treatment 0.251 0.00267 0.14 0.1437 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N15 compound treatment 0.279 0.0307 1.65 1.6484 1.0 1682300 Bionet2_001661 CCN(CC)c1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N16 mock treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N17 compound treatment 0.286 0.0377 2.02 2.0245 1.0 1912283 Bionet2_001662 O/N=C/c1c(nc2sccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N18 mock treatment 0.256 0.00767 0.41 0.4124 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N19 compound treatment 0.344 0.0957 5.14 5.1413 1.0 1912284 Bionet2_001663 FC(F)(F)c1cccc(Sc2ccc3nnc(Cl)n3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N20 mock treatment 0.253 0.00467 0.25 0.2512 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N21 compound treatment 0.269 0.0207 1.11 1.111 1.0 1912285 Bionet2_001664 CSc1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N22 mock treatment 0.246 -0.00233 -0.12 -0.125 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N23 mock treatment 0.252 0.00367 0.2 0.1974 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 N24 mock treatment 0.235 -0.0133 -0.72 -0.7161 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O01 compound treatment 0.233 -0.0153 -0.82 -0.8236 -1.0 1912286 Bionet2_001665 COc1ccc(cc1)C(=C2C(=O)c3ccccc3C2=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O02 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1912287 Bionet2_001666 COC(=O)C(N)Cc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O03 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1912288 Bionet2_001667 Clc1ccc(CN2CCN(CC2)c3ccccc3)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O04 compound treatment 0.266 0.0177 0.95 0.9498 1.0 1912289 Bionet2_001668 CSc1ccccc1C(=O)Nc2cc(C)cc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O05 compound treatment 0.274 0.0257 1.38 1.3797 1.0 1912290 Bionet2_001669 Clc1ccc(CN2CCC(Cc3ccccc3)CC2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O06 compound treatment 0.256 0.00767 0.41 0.4124 1.0 1912291 Bionet2_001670 OC(=O)C(Cc1ccccc1)NC(=O)c2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O07 compound treatment 0.42 0.172 9.23 9.2254 1.0 1912292 Bionet2_001671 COc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(C)cc2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O08 compound treatment 0.297 0.0487 2.62 2.6156 1.0 1912293 Bionet2_001672 CCOc1ccc(/C=C/C(=O)CCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O09 compound treatment 0.506 0.258 13.85 13.8469 1.0 1912294 Bionet2_001673 COC(=O)c1ccc(OCc2ccc(Cl)nc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O10 compound treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1912295 Bionet2_001674 ONc1cccnc1n2nc(cc2C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O11 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1912296 Bionet2_001675 C1Oc2ccc(/C=N/c3ccccc3)cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O12 compound treatment 0.249 6.74E-4 0.04 0.0362 1.0 1912297 Bionet2_001676 Cc1cccnc1NC(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O13 compound treatment 0.269 0.0207 1.11 1.111 1.0 1912298 Bionet2_001677 Nc1nccc(n1)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O14 compound treatment 0.259 0.0107 0.57 0.5736 1.0 1912299 Bionet2_001678 CC(C)(C)C(=O)Cc1nc(O)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O15 compound treatment 0.27 0.0217 1.16 1.1647 1.0 1912300 Bionet2_001679 COC(=O)c1cnc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O16 compound treatment 0.356 0.108 5.79 5.7862 1.0 1912301 Bionet2_001680 Clc1ccc2NC(=O)/C(=C\Nc3ccccc3)/Sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O17 compound treatment 0.574 0.326 17.5 17.501 1.0 1380177 Bionet2_001681 Clc1ccc(cc1)C(=O)CC2OC(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O18 compound treatment 0.492 0.244 13.09 13.0945 1.0 1912302 Bionet2_001682 CN(C)c1nn(cc1c2ccccc2)C(=S)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O19 compound treatment 0.278 0.0297 1.59 1.5946 1.0 1201038 Bionet2_001683 COc1ccccc1C(C#N)c2cccc(Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O20 compound treatment 0.321 0.0727 3.91 3.9053 1.0 1912303 Bionet2_001684 FC(F)(F)c1cccc(N/C=C(\C#N)/c2ccc(Cl)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O21 compound treatment 0.27 0.0217 1.16 1.1647 1.0 1912304 Bionet2_001685 CS/C(=N/c1ccccc1)/NCc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O22 compound treatment 0.264 0.0157 0.84 0.8423 1.0 1912305 Bionet2_001686 S(c1ccccc1)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O23 mock treatment 0.262 0.0137 0.73 0.7348 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 O24 mock treatment 0.256 0.00767 0.41 0.4124 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P01 compound treatment 0.39 0.142 7.61 7.6133 1.0 1912306 Bionet2_001687 CN(C)C(=O)CSc1cnc2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P02 compound treatment 0.238 -0.0103 -0.55 -0.5549 -1.0 1912307 Bionet2_001688 Cc1nc(N)nc(Sc2ccc(Cl)cc2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P03 compound treatment 0.271 0.0227 1.22 1.2184 1.0 1541367 Bionet2_001689 Nc1c(cnc2ncnn12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P04 compound treatment 0.253 0.00467 0.25 0.2512 1.0 1912308 Bionet2_001690 COc1ccc(c(OC)c1)n2cc3ccsc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P05 compound treatment 0.26 0.0117 0.63 0.6273 1.0 1912309 Bionet2_001691 Fc1ccc(N/C=C/2\C(=O)N(CS2=O)c3ccc(F)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P06 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1193117 Bionet2_001692 COC(=O)Nc1cn(Cc2ccccn2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P07 compound treatment 0.276 0.0277 1.49 1.4871 1.0 1713483 Bionet2_001693 Clc1ccc(cc1Cl)c2ccnc3c(C#N)cnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P08 mock treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P09 compound treatment 0.255 0.00667 0.36 0.3586 1.0 1912310 Bionet2_001694 Clc1ccccc1CSc2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P10 mock treatment 0.242 -0.00633 -0.34 -0.34 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P11 compound treatment 0.292 0.0437 2.35 2.3469 1.0 1124817 Bionet2_001695 NC(=C(C#N)C#N)COc1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P12 mock treatment 0.237 -0.0113 -0.61 -0.6086 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P13 compound treatment 0.266 0.0177 0.95 0.9498 1.0 1912311 Bionet2_001696 Oc1ccccc1/N=C/c2c(Cl)nc3sccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P14 mock treatment 0.245 -0.00333 -0.18 -0.1787 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P15 compound treatment 0.252 0.00367 0.2 0.1974 1.0 1912312 Bionet2_001697 C=CCNc1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P16 mock treatment 0.244 -0.00433 -0.23 -0.2325 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P17 compound treatment 0.275 0.0267 1.43 1.4334 1.0 1103127 Bionet2_001698 N#Cc1c(nc2sccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P18 mock treatment 0.239 -0.00933 -0.5 -0.5012 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P19 compound treatment 0.291 0.0427 2.29 2.2932 1.0 1912313 Bionet2_001699 FC(F)(F)c1cccc(c1)S(=O)c2ccc3nnc(Cl)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P20 mock treatment 0.234 -0.0143 -0.77 -0.7699 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P21 compound treatment 0.243 -0.00533 -0.29 -0.2862 -1.0 1912314 Bionet2_001700 CC(C)Nc1cc(nc(n1)c2ccccn2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P22 mock treatment 0.241 -0.00733 -0.39 -0.3937 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P23 mock treatment 0.249 6.74E-4 0.04 0.0362 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1368 P24 mock treatment 0.239 -0.00933 -0.5 -0.5012 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A01 compound treatment 0.269 0.026 1.4 1.3989 1.0 1983483 ChemDiv2_000001 Brc1ccc(cc1)c2nc(cc(=O)[nH]2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A02 compound treatment 0.227 -0.016 -0.86 -0.8581 -1.0 1016552 ChemDiv2_000002 OC(=O)C(Cc1ccccc1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A03 compound treatment 0.274 0.031 1.67 1.6676 1.0 1720014 ChemDiv2_000003 OC(=O)COc1ccc(C(=O)Cc2ccc3OCCCOc3c2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A04 compound treatment 0.234 -0.00897 -0.48 -0.482 -1.0 1983484 ChemDiv2_000004 CC(=O)OCCNc1ccc2noc3-c4ccccc4C(=O)c1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A05 compound treatment 0.233 -0.00997 -0.54 -0.5357 -1.0 1519182 ChemDiv2_000005 OC(=O)CCc1nc2ccccc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A06 compound treatment 0.228 -0.015 -0.8 -0.8044 -1.0 1012562 ChemDiv2_000006 N#CCCN1CCN(CCC#N)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A07 compound treatment 0.229 -0.014 -0.75 -0.7507 -1.0 1642646 ChemDiv2_000007 CCOC(=O)C1Nc2c(C)c(ccc2C3C=CCC31)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A08 compound treatment 0.233 -0.00997 -0.54 -0.5357 -1.0 1983485 ChemDiv2_000008 CCCN(CCC)C(=O)C1C(C2CC1C=C2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A09 compound treatment 0.408 0.165 8.87 8.8684 1.0 1193500 ChemDiv2_000009 CC(=O)N(C1SC(=O)N(C1=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A10 compound treatment 0.393 0.15 8.06 8.0624 1.0 1983486 ChemDiv2_000010 O/N=C/c1ccc2cccc(O)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A11 compound treatment 0.267 0.024 1.29 1.2914 1.0 1983487 ChemDiv2_000011 O=S(=O)(CCC#N)c1ccc(Cc2ccc(cc2)S(=O)(=O)CCC#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A12 compound treatment 0.456 0.213 11.45 11.4479 1.0 1579024 ChemDiv2_000012 O=C(Nc1nonc1NC(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A13 compound treatment 0.233 -0.00997 -0.54 -0.5357 -1.0 1003119 ChemDiv2_000013 O=C(CC(=O)Nc1ccccc1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A14 compound treatment 0.231 -0.012 -0.64 -0.6432 -1.0 1381677 ChemDiv2_000014 O=C(Oc1ccc(OC(=O)c2ccco2)c(C#N)c1C#N)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A15 compound treatment 0.23 -0.013 -0.7 -0.6969 -1.0 1685226 ChemDiv2_000015 Nc1cc(C(=O)O)c(Oc2ccc(Cl)cc2Cl)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A16 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1333910 ChemDiv2_000016 Nc1ccc(Oc2ccc(cc2)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A17 compound treatment 0.287 0.044 2.37 2.3661 1.0 1251693 ChemDiv2_000017 CCOC(=O)c1ccccc1S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A18 compound treatment 0.271 0.028 1.51 1.5063 1.0 1068289 ChemDiv2_000018 Clc1ccc(cc1)S(=O)(=O)N2CCOC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A19 compound treatment 0.256 0.013 0.7 0.7003 1.0 1983488 ChemDiv2_000019 CC(=O)N1CC(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A20 compound treatment 0.257 0.014 0.75 0.754 1.0 1368266 ChemDiv2_000020 O=C(Nc1ccccc1)c2ccc3C(=O)c4ccccc4-c5onc2c53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A21 compound treatment 0.281 0.038 2.04 2.0437 1.0 1138701 ChemDiv2_000021 CN(C)c1c(N)c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A22 compound treatment 0.254 0.011 0.59 0.5928 1.0 1118921 ChemDiv2_000022 CCOC(=O)C1C(CN(C(=O)c2ccc(OC)cc2)C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A23 mock treatment 0.244 0.00103 0.06 0.0554 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 A24 mock treatment 0.26 0.017 0.92 0.9152 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B01 compound treatment 0.261 0.018 0.97 0.969 1.0 1679054 ChemDiv2_000023 OC(=O)COc1ccc-2c(c1)C(=O)c3cc(OCC(=O)O)ccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B02 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1302745 ChemDiv2_000024 CCC(C)NC(=O)c1ccccc1c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B03 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1220490 ChemDiv2_000025 CC(=O)N(C(=O)C)c1c(N2CCCC2)c3ccccc3oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B04 compound treatment 0.455 0.212 11.39 11.3941 1.0 1365627 ChemDiv2_000026 Cc1ccc(OCC(=O)NCCc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B05 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1983489 ChemDiv2_000027 CN(C)C(=O)c1ccc2CCc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B06 compound treatment 0.262 0.019 1.02 1.0227 1.0 1673236 ChemDiv2_000028 Nc1cc(CCCC(=O)O)sc1CCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B07 compound treatment 0.286 0.043 2.31 2.3124 1.0 1983490 ChemDiv2_000029 O/N=C/c1cccc(C(=O)O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B08 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1670947 ChemDiv2_000030 OC(C#CCN1CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B09 compound treatment 0.248 0.00503 0.27 0.2704 1.0 1983491 ChemDiv2_000031 Cn1ncc2nnn(c3ccccc3)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B10 compound treatment 0.243 3.12E-5 0.0 0.0017 1.0 1281145 ChemDiv2_000032 OCCN1CCN(CCN2CCn3c2nc4ccccc34)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B11 compound treatment 0.246 0.00303 0.16 0.1629 1.0 1180567 ChemDiv2_000033 OC(CNC1CCCCC1)CNC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B12 compound treatment 0.267 0.024 1.29 1.2914 1.0 1983492 ChemDiv2_000034 O=C1NCC(=C1)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B13 compound treatment 0.399 0.156 8.38 8.3848 1.0 1523758 ChemDiv2_000035 OC1(COc2ccccc2O1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B14 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1983493 ChemDiv2_000036 COC(=O)CCC(=O)Nc1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B15 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1983494 ChemDiv2_000037 OC[C@H]1O[C@@H]2C(Oc3nc(=O)ccn23)[C@H]1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B16 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1983495 ChemDiv2_000038 CC1CCN(CC1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B17 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1983496 ChemDiv2_000039 Cc1cc(C)n(n1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B18 compound treatment 0.526 0.283 15.21 15.2095 1.0 1174610 ChemDiv2_000040 Cc1cccc(NC(=O)c2cc3ccccc3o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B19 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1983497 ChemDiv2_000041 Brc1ccccc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B20 compound treatment 0.27 0.027 1.45 1.4526 1.0 1004101 ChemDiv2_000042 COc1ccccc1NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B21 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1780857 ChemDiv2_000043 CCOC(=O)CSc1nc(=O)c(NCC(=O)OC)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B22 compound treatment 0.251 0.00803 0.43 0.4316 1.0 1781228 ChemDiv2_000044 COC(=O)CCc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B23 mock treatment 0.245 0.00203 0.11 0.1092 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 B24 mock treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C01 compound treatment 0.418 0.175 9.41 9.4058 1.0 1565050 ChemDiv2_000045 CC(=O)Nc1ccc(C(=O)c2ccccc2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C02 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1489045 ChemDiv2_000046 CN1CCN(CCCC(=O)Nc2c(C)cc(C)cc2C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C03 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1983498 ChemDiv2_000047 OC(=O)c1ccc2C(=O)n3c(nc4ccccc34)-c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C04 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1346852 ChemDiv2_000048 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C05 compound treatment 0.309 0.066 3.55 3.5484 1.0 1692917 ChemDiv2_000049 CCOC(=O)c1cc2C(=O)c3ccccc3-n2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C06 compound treatment 0.233 -0.00997 -0.54 -0.5357 -1.0 1983499 ChemDiv2_000050 CCN1CCC(=NO)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C07 compound treatment 0.254 0.011 0.59 0.5928 1.0 1263031 ChemDiv2_000051 Cc1cc(C)c2c(O)nc(SCC(=O)O)nc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C08 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1983500 ChemDiv2_000052 COC(=O)C(C)OC(=O)c1ccc(Cl)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C09 compound treatment 0.42 0.177 9.51 9.5133 1.0 1983501 ChemDiv2_000053 ClCCCn1c(=O)[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C10 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1921327 ChemDiv2_000054 OCCSc1c(F)c(F)c(SCCO)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C11 compound treatment 0.273 0.03 1.61 1.6138 1.0 1502394 ChemDiv2_000055 COC(=O)CCS(=O)(=O)c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C12 compound treatment 0.243 3.12E-5 0.0 0.0017 1.0 1002875 ChemDiv2_000056 OCC1COc2ccccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C13 compound treatment 0.287 0.044 2.37 2.3661 1.0 1983502 ChemDiv2_000057 CC(C)COC(=O)c1ccc(O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C14 compound treatment 0.258 0.015 0.81 0.8077 1.0 1190916 ChemDiv2_000058 CC(C)COC(=O)c1ccccc1OC(=O)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C15 compound treatment 0.34 0.097 5.21 5.2143 1.0 1423723 ChemDiv2_000059 O=C1CCNc2ccc(cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C16 compound treatment 0.257 0.014 0.75 0.754 1.0 1016413 ChemDiv2_000060 OC(=O)C1(CCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C17 compound treatment 0.254 0.011 0.59 0.5928 1.0 1983503 ChemDiv2_000061 Cc1ccn(CO)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C18 compound treatment 0.276 0.033 1.78 1.775 1.0 1983504 ChemDiv2_000062 O=C(Oc1ccccc1)n2c(=S)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C19 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1302032 ChemDiv2_000063 O=C1CN(CC(=O)N1CCc2ccccc2)S(=O)(=O)CCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C20 compound treatment 0.339 0.096 5.16 5.1605 1.0 1018145 ChemDiv2_000064 Oc1ccc(Br)cc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C21 compound treatment 0.292 0.049 2.63 2.6348 1.0 1212582 ChemDiv2_000065 Nc1c(N2CCCCC2)c3ccccc3oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C22 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1577618 ChemDiv2_000066 OC(=O)C1C(CNC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C23 mock treatment 0.255 0.012 0.65 0.6465 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 C24 mock treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D01 compound treatment 0.234 -0.00897 -0.48 -0.482 -1.0 1391083 ChemDiv2_000067 O=C1C2CN3CC1(CN(C2)CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D02 compound treatment 0.444 0.201 10.8 10.803 1.0 1156177 ChemDiv2_000068 O=C(NCCc1ccccc1)c2ccc3[nH]cnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D03 compound treatment 0.305 0.062 3.33 3.3334 1.0 1211005 ChemDiv2_000069 N=c1sccn1CC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D04 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1983505 ChemDiv2_000070 CCN(CC)C(=O)COc1cc(C)ccc1C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D05 compound treatment 0.254 0.011 0.59 0.5928 1.0 1013613 ChemDiv2_000071 OC(=O)Cc1ccc2CCc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D06 compound treatment 0.248 0.00503 0.27 0.2704 1.0 1471312 ChemDiv2_000072 CN(C)CCCN1C(=O)CCCCc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D07 compound treatment 0.251 0.00803 0.43 0.4316 1.0 1010969 ChemDiv2_000073 O=C(c1ccccc1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D08 compound treatment 0.234 -0.00897 -0.48 -0.482 -1.0 1983506 ChemDiv2_000074 CCC1(O)CC(C)N(C)CC1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D09 compound treatment 0.236 -0.00697 -0.37 -0.3745 -1.0 1491510 ChemDiv2_000075 CCC(C)(O)c1nnn(c2nonc2N)c1C(C)(O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D10 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1937732 ChemDiv2_000076 CCc1ncc(C(O)c2ccccc2)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D11 compound treatment 0.318 0.075 4.03 4.032 1.0 1297399 ChemDiv2_000077 CCN1C(=O)C(SC1=S)C(=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D12 compound treatment 0.234 -0.00897 -0.48 -0.482 -1.0 1527285 ChemDiv2_000078 OC(=O)C1CC=CCC1C(=O)Nc2cccc(c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D13 compound treatment 0.284 0.041 2.2 2.2049 1.0 1690603 ChemDiv2_000079 CCc1cc(c2n[nH]cc2c3cscn3)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D14 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1983507 ChemDiv2_000080 CC(Oc1cccc(Cl)c1)n2cncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D15 compound treatment 0.236 -0.00697 -0.37 -0.3745 -1.0 1921382 ChemDiv2_000081 O=C(Cc1ccccc1)NCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D16 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1983508 ChemDiv2_000082 CN(C1CCCCC1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D17 compound treatment 0.263 0.02 1.08 1.0764 1.0 1717876 ChemDiv2_000083 COc1cccc2ccc(=O)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D18 compound treatment 0.541 0.298 16.02 16.0156 1.0 1712967 ChemDiv2_000084 COC(=O)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D19 compound treatment 0.325 0.082 4.41 4.4082 1.0 1195277 ChemDiv2_000085 Nc1c(nnn1Cc2ccccc2)C3=NCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D20 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1009044 ChemDiv2_000086 Cc1cccc(NC(=O)c2ccccc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D21 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1642812 ChemDiv2_000087 Cc1cc(=O)oc2cc(OC(=O)c3ccco3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D22 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1983509 ChemDiv2_000088 CN(C)c1c(C)nc(O)nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D23 mock treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 D24 mock treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E01 compound treatment 0.236 -0.00697 -0.37 -0.3745 -1.0 1983510 ChemDiv2_000089 CCCc1nn(c(CCC)c1CC)c2ccc(=O)[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E02 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1311971 ChemDiv2_000090 CCc1nc(C)ccc1OCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E03 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1375698 ChemDiv2_000091 OC(=O)c1ccc(cc1)c2ccc(O)c(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E04 compound treatment 0.246 0.00303 0.16 0.1629 1.0 1005213 ChemDiv2_000092 CN(C)c1ccc(cc1)c2ccc(cc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E05 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1309783 ChemDiv2_000093 Oc1ccc2OC3(CCCCC3c2c1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E06 compound treatment 0.274 0.031 1.67 1.6676 1.0 1983511 ChemDiv2_000094 BrCCc1nc(CCBr)n(Cc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E07 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1010682 ChemDiv2_000095 OC(=O)C1(O)c2ccccc2-c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E08 compound treatment 0.548 0.305 16.39 16.3917 1.0 1636834 ChemDiv2_000096 CC(=O)Nc1ccc(cc1)c2nc3c(Cl)cccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E09 compound treatment 0.254 0.011 0.59 0.5928 1.0 1983512 ChemDiv2_000097 N#Cc1ccc(/C=C/c2ccc(C#N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E10 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1125917 ChemDiv2_000098 CCOc1ccccc1OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E11 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1052399 ChemDiv2_000099 O=C1CCC(CC1)C2CCC(=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E12 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1042714 ChemDiv2_000100 Cc1ncc(CO)c2COC(C)(C)Oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E13 compound treatment 0.236 -0.00697 -0.37 -0.3745 -1.0 1616529 ChemDiv2_000101 CCC(Oc1ccc(c(C)c1)C(C)(C)CC)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E14 compound treatment 0.402 0.159 8.55 8.546 1.0 1687174 ChemDiv2_000102 CCOC(=O)CC(=O)Nc1ccc(cc1)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E15 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1983513 ChemDiv2_000103 CCn1c(C)nc2cc(CO)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E16 compound treatment 0.384 0.141 7.58 7.5787 1.0 1501259 ChemDiv2_000104 O=C(Nc1cccc(OC(=O)c2cccnc2)c1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E17 compound treatment 0.317 0.074 3.98 3.9783 1.0 1116263 ChemDiv2_000105 CC(=O)n1ccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E18 compound treatment 0.281 0.038 2.04 2.0437 1.0 1550751 ChemDiv2_000106 Cc1ccc(O)c(CN2CCN(CC2)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E19 compound treatment 0.449 0.206 11.07 11.0717 1.0 1011862 ChemDiv2_000107 O=C(CCc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E20 compound treatment 0.257 0.014 0.75 0.754 1.0 1570986 ChemDiv2_000108 CC1=Nc2ccc(C)cc2N(Cc3ccccc3)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E21 compound treatment 0.282 0.039 2.1 2.0975 1.0 1983514 ChemDiv2_000109 O/N=C/C(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E22 compound treatment 0.264 0.021 1.13 1.1302 1.0 1595215 ChemDiv2_000110 COC(=O)c1c(C)nc(C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E23 mock treatment 0.246 0.00303 0.16 0.1629 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 E24 mock treatment 0.248 0.00503 0.27 0.2704 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F01 compound treatment 0.272 0.029 1.56 1.5601 1.0 1655507 ChemDiv2_000111 Nc1nc(cc(=O)[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F02 compound treatment 0.432 0.189 10.16 10.1581 1.0 1318801 ChemDiv2_000112 Cc1ccc(NC(=O)COc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F03 compound treatment 0.273 0.03 1.61 1.6138 1.0 1451006 ChemDiv2_000113 C=CCOC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F04 compound treatment 0.41 0.167 8.98 8.9759 1.0 1516059 ChemDiv2_000114 NS(=O)(=O)c1ccc(NC(=O)COc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F05 compound treatment 0.312 0.069 3.71 3.7096 1.0 1983515 ChemDiv2_000115 C1Cc2nc(cn2C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F06 compound treatment 0.27 0.027 1.45 1.4526 1.0 1983516 ChemDiv2_000116 CSc1ccc(s1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F07 compound treatment 0.534 0.291 15.64 15.6394 1.0 1419480 ChemDiv2_000117 CN(C)c1ccc(cc1)c2nc3cc(N)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F08 compound treatment 0.258 0.015 0.81 0.8077 1.0 1983517 ChemDiv2_000118 O/N=C(/CCc1ccccc1)\C2(O)CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F09 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1583162 ChemDiv2_000119 Cn1c(O)c(C(=O)c2ccccc2)c(=O)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F10 compound treatment 0.355 0.112 6.02 6.0203 1.0 1698928 ChemDiv2_000120 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(CO)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F11 compound treatment 0.352 0.109 5.86 5.8591 1.0 1983518 ChemDiv2_000121 O=C1CC(=Nc2ccccc2N1)/C=C/c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F12 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1119326 ChemDiv2_000122 OCCNC(=O)c1cccc2Cc3cc(I)ccc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F13 compound treatment 0.266 0.023 1.24 1.2377 1.0 1515023 ChemDiv2_000123 CC(=O)OC1(COc2ccccc2O1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F14 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1429897 ChemDiv2_000124 Cc1c(C#N)c(N)sc1C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F15 compound treatment 0.287 0.044 2.37 2.3661 1.0 1455150 ChemDiv2_000125 COc1cc2CC(C)(C)n3c(nc4ccccc4c3=O)-c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F16 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1025749 ChemDiv2_000126 CS(=O)(=O)NCc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F17 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1983519 ChemDiv2_000127 Clc1cc(Cl)c2cccnc2c1N(C(=O)c3ccco3)C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F18 compound treatment 0.461 0.218 11.72 11.7165 1.0 1489396 ChemDiv2_000128 CCOC(=O)c1ccccc1NC(=O)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F19 compound treatment 0.243 3.12E-5 0.0 0.0017 1.0 1027265 ChemDiv2_000129 OC(=O)CC1(CC(=O)O)CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F20 compound treatment 0.375 0.132 7.1 7.0951 1.0 1983520 ChemDiv2_000130 Clc1ccccc1c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F21 compound treatment 0.23 -0.013 -0.7 -0.6969 -1.0 1983521 ChemDiv2_000131 CC(C)C(N1C(=O)CSC1=S)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F22 compound treatment 0.54 0.297 15.96 15.9618 1.0 1983522 ChemDiv2_000132 CC(C)C(=O)c1ccc(OCCOc2ccc(C#N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F23 mock treatment 0.246 0.00303 0.16 0.1629 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 F24 mock treatment 0.232 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G01 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1457725 ChemDiv2_000133 CC1(C)CC(=CC(C)(C)N1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G02 compound treatment 0.326 0.083 4.46 4.4619 1.0 1290876 ChemDiv2_000134 CCN(CC)CCNc1c(N)c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G03 compound treatment 0.273 0.03 1.61 1.6138 1.0 1319814 ChemDiv2_000135 NS(=O)(=O)c1cccc2cc(C(=O)O)c(O)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G04 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1037947 ChemDiv2_000136 OC(C(=O)O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G05 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1665488 ChemDiv2_000137 CN1CCN(CCN2CCn3c2nc4ccccc34)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G06 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1684346 ChemDiv2_000138 CNCCc1n[nH]c(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G07 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1983523 ChemDiv2_000139 Cc1ccccc1C2CCC(=O)NC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G08 compound treatment 0.275 0.032 1.72 1.7213 1.0 1983524 ChemDiv2_000140 COC(=O)c1ccc2cc(ccc2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G09 compound treatment 0.274 0.031 1.67 1.6676 1.0 1729986 ChemDiv2_000141 Cc1ccccc1NC(=O)COc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G10 compound treatment 0.287 0.044 2.37 2.3661 1.0 1715440 ChemDiv2_000142 O=c1[nH]nc(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G11 compound treatment 0.279 0.036 1.94 1.9362 1.0 1040327 ChemDiv2_000143 CC(=O)Nc1cc2ccccc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G12 compound treatment 0.231 -0.012 -0.64 -0.6432 -1.0 1511738 ChemDiv2_000144 Oc1ccccc1OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G13 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1357655 ChemDiv2_000145 NCC(CC(=O)O)C1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G14 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1321767 ChemDiv2_000146 CNC(=O)CC(=O)Nc1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G15 compound treatment 0.279 0.036 1.94 1.9362 1.0 1983525 ChemDiv2_000147 Cc1nc2ccc(CCO)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G16 compound treatment 0.295 0.052 2.8 2.7961 1.0 1555390 ChemDiv2_000148 Brc1cccc(OC(=O)c2cccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G17 compound treatment 0.304 0.061 3.28 3.2797 1.0 1983526 ChemDiv2_000149 CC(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G18 compound treatment 0.277 0.034 1.83 1.8288 1.0 1391067 ChemDiv2_000150 O=C(N1CCOCC1)c2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G19 compound treatment 0.397 0.154 8.28 8.2773 1.0 1003767 ChemDiv2_000151 O=C1N(Cc2ccccc2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G20 compound treatment 0.253 0.01 0.54 0.5391 1.0 1983527 ChemDiv2_000152 C/C(=N\O)/C\1C2C(C/C1=N\O)C2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G21 compound treatment 0.255 0.012 0.65 0.6465 1.0 1540583 ChemDiv2_000153 Cc1ccc(cc1)S(=O)(=O)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G22 compound treatment 0.253 0.01 0.54 0.5391 1.0 1682996 ChemDiv2_000154 CN1C2CCC1CC(C2)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G23 mock treatment 0.246 0.00303 0.16 0.1629 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 G24 mock treatment 0.231 -0.012 -0.64 -0.6432 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H01 compound treatment 0.262 0.019 1.02 1.0227 1.0 1637142 ChemDiv2_000155 CCCOc1ccccc1NC(=O)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H02 compound treatment 0.253 0.01 0.54 0.5391 1.0 1126433 ChemDiv2_000156 CCOc1ccccc1NC(=O)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H03 compound treatment 0.297 0.054 2.9 2.9035 1.0 1247178 ChemDiv2_000157 CN(C)c1nc2ccc(O)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H04 compound treatment 0.265 0.022 1.18 1.1839 1.0 1983528 ChemDiv2_000158 CC(=O)/N=C/1\NC(=O)CS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H05 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1983529 ChemDiv2_000159 C1CN=C(C1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H06 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1983530 ChemDiv2_000160 CCSc1sc(CC)cc1CCl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H07 compound treatment 0.355 0.112 6.02 6.0203 1.0 1628407 ChemDiv2_000161 OC(=O)c1cc2cccc(c2cc1O)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H08 compound treatment 0.243 3.12E-5 0.0 0.0017 1.0 1649045 ChemDiv2_000162 CC1CC2(C)CC(C1C(=O)O)C(=O)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H09 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1983531 ChemDiv2_000163 CCN(CC)CCn1c(OC)cc(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H10 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1983532 ChemDiv2_000164 CC1CN(CC(C)O1)C(=O)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H11 compound treatment 0.234 -0.00897 -0.48 -0.482 -1.0 1006824 ChemDiv2_000165 COc1ccccc1CC(CC(=O)O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H12 compound treatment 0.311 0.068 3.66 3.6559 1.0 1317998 ChemDiv2_000166 CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3c(C)cccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H13 compound treatment 0.23 -0.013 -0.7 -0.6969 -1.0 1199588 ChemDiv2_000167 CC(C)NCC(O)COc1c(F)cc(Br)cc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H14 compound treatment 0.289 0.046 2.47 2.4736 1.0 1983533 ChemDiv2_000168 COC(=O)COc1ccc-2c(c1)C(=O)c3cc(OCC(=O)OC)ccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H15 compound treatment 0.426 0.183 9.84 9.8357 1.0 1912568 ChemDiv2_000169 Brc1ccc(SCCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H16 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1983534 ChemDiv2_000170 CS(=O)(=O)N1CCCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H17 compound treatment 0.359 0.116 6.24 6.2353 1.0 1983535 ChemDiv2_000171 CCn1c(C)csc1=NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H18 compound treatment 0.392 0.149 8.01 8.0086 1.0 1501913 ChemDiv2_000172 CCCc1ccc(OCC(=O)NC2CCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H19 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1009055 ChemDiv2_000173 O=C1C(CCC#N)(CCC#N)CCCC1(CCC#N)CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H20 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1267090 ChemDiv2_000174 S=c1[nH]nc(o1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H21 compound treatment 0.42 0.177 9.51 9.5133 1.0 1383109 ChemDiv2_000175 CC(C)C(=O)Nc1ccc(C(=O)Oc2ccccc2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H22 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1150730 ChemDiv2_000176 CC1C=C(C)CC2C1C(=O)N(Cc3ccco3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H23 mock treatment 0.235 -0.00797 -0.43 -0.4282 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 H24 mock treatment 0.245 0.00203 0.11 0.1092 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I01 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1381635 ChemDiv2_000177 Oc1cccc2ccc(Nc3ccccn3)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I02 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1983536 ChemDiv2_000178 CCOC(=O)C(N)CSC1CCCCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I03 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1063046 ChemDiv2_000179 OC(=O)C12C3C4C2C5C1C3C45C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I04 compound treatment 0.304 0.061 3.28 3.2797 1.0 1051410 ChemDiv2_000180 Cc1ccc(O)c(c1)n2nc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I05 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1410705 ChemDiv2_000181 OC(=O)CC1OC(=O)c2cc3C(CC(=O)O)OC(=O)c3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I06 compound treatment 0.251 0.00803 0.43 0.4316 1.0 1016614 ChemDiv2_000182 CN(C)c1ccc(cc1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I07 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1009929 ChemDiv2_000183 Oc1ccc(cc1Br)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I08 compound treatment 0.273 0.03 1.61 1.6138 1.0 1046129 ChemDiv2_000184 OC(=O)c1cccc(c1)c2cccc(c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I09 compound treatment 0.32 0.077 4.14 4.1395 1.0 1004794 ChemDiv2_000185 OC(=O)c1ccccc1NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I10 compound treatment 0.301 0.058 3.12 3.1185 1.0 1190082 ChemDiv2_000186 Cc1ccc(cc1)S(=O)(=O)N(CCC#N)CCN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I11 compound treatment 0.275 0.032 1.72 1.7213 1.0 1013152 ChemDiv2_000187 O=C(C1C(=O)c2ccccc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I12 compound treatment 0.251 0.00803 0.43 0.4316 1.0 1363366 ChemDiv2_000188 CCN(CC)c1c(CN2CCCC2)c(=O)oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I13 compound treatment 0.315 0.072 3.87 3.8708 1.0 1488771 ChemDiv2_000189 Nc1ccc(Oc2cccc(Oc3ccc(N)cc3)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I14 compound treatment 0.388 0.145 7.79 7.7937 1.0 1501265 ChemDiv2_000190 O=C(Oc1ccccc1)Oc2ccc3sc(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I15 compound treatment 0.275 0.032 1.72 1.7213 1.0 1080577 ChemDiv2_000191 CCOC(=O)c1cc(O)c(cc1O)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I16 compound treatment 0.262 0.019 1.02 1.0227 1.0 1326101 ChemDiv2_000192 COC(=O)c1ccc(cc1)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I17 compound treatment 0.269 0.026 1.4 1.3989 1.0 1983537 ChemDiv2_000193 O/N=C/c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I18 compound treatment 0.608 0.365 19.62 19.616 1.0 1913415 ChemDiv2_000194 C(CSc1nnnn1c2ccccc2)Sc3nnnn3c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I19 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1983538 ChemDiv2_000195 CS(=O)(=O)c1ccc(Cl)c(c1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I20 compound treatment 0.365 0.122 6.56 6.5577 1.0 1273303 ChemDiv2_000196 COc1ccc(cc1OC)C(=O)Oc2ccc3c(C)cc(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I21 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1021069 ChemDiv2_000197 OC(=O)c1ccccc1Nc2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I22 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1002853 ChemDiv2_000198 Oc1ccc(cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I23 mock treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 I24 mock treatment 0.25 0.00703 0.38 0.3778 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J01 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1983539 ChemDiv2_000199 CCC1(CC)CC(=O)C=NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J02 compound treatment 0.285 0.042 2.26 2.2587 1.0 1620586 ChemDiv2_000200 COc1ccc(OC)c(NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J03 compound treatment 0.415 0.172 9.24 9.2446 1.0 1262230 ChemDiv2_000201 O=C(Nc1ccc2C(=O)NC(=O)c2c1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J04 compound treatment 0.356 0.113 6.07 6.0741 1.0 1983540 ChemDiv2_000202 O=S(=O)(c1ccsc1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J05 compound treatment 0.272 0.029 1.56 1.5601 1.0 1464075 ChemDiv2_000203 CCN(CC)C(=O)c1csc(c1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J06 compound treatment 0.255 0.012 0.65 0.6465 1.0 1308867 ChemDiv2_000204 COC(=O)Oc1cncc(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J07 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1417108 ChemDiv2_000205 Nc1nnnn1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J08 compound treatment 0.311 0.068 3.66 3.6559 1.0 1189179 ChemDiv2_000206 Fc1ccc(cc1)C(=O)CCCN2CCN3CCCC3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J09 compound treatment 0.258 0.015 0.81 0.8077 1.0 1110167 ChemDiv2_000207 CC(C)C(=O)Nc1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J10 compound treatment 0.355 0.112 6.02 6.0203 1.0 1934677 ChemDiv2_000208 OCn1nc(oc1=S)c2ccccc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J11 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1146108 ChemDiv2_000209 CC(C(Cc1cc(C)cc(C)c1)C(=O)O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J12 compound treatment 0.321 0.078 4.19 4.1932 1.0 1983541 ChemDiv2_000210 COC(=O)COc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J13 compound treatment 0.31 0.067 3.6 3.6021 1.0 1983542 ChemDiv2_000211 CCOC(=O)c1sc2ncnc(N)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J14 compound treatment 0.258 0.015 0.81 0.8077 1.0 1724975 ChemDiv2_000212 OC(=O)C1C2CC=CC2c3cc(Br)cc4C5C=CCC5CN1c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J15 compound treatment 0.396 0.153 8.22 8.2236 1.0 1915572 ChemDiv2_000213 Clc1ccc(Cl)c(SCCc2ccncc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J16 compound treatment 0.306 0.063 3.39 3.3872 1.0 1555922 ChemDiv2_000214 Cc1ccc(OCC(=O)NCC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J17 compound treatment 0.327 0.084 4.52 4.5157 1.0 1660956 ChemDiv2_000215 OCCS(=O)(=O)c1ccc2oc(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J18 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1983543 ChemDiv2_000216 c1ccc(cc1)c2nnc(c3ccccc3)n2c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J19 compound treatment 0.271 0.028 1.51 1.5063 1.0 1288387 ChemDiv2_000217 Nc1nc2ccc(cc2s1)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J20 compound treatment 0.399 0.156 8.38 8.3848 1.0 1983544 ChemDiv2_000218 Cc1ccccc1c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J21 compound treatment 0.249 0.00603 0.32 0.3241 1.0 1518713 ChemDiv2_000219 OC(=O)C(Cc1ccccc1)N2C(=O)CSC2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J22 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1280084 ChemDiv2_000220 CC1C=C(C)CC2C1C(=O)N(CCCN(C)C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J23 mock treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 J24 mock treatment 0.23 -0.013 -0.7 -0.6969 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K01 compound treatment 0.23 -0.013 -0.7 -0.6969 -1.0 1983545 ChemDiv2_000221 CC(=O)NC1=CC(=O)c2nonc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K02 compound treatment 0.263 0.02 1.08 1.0764 1.0 1094456 ChemDiv2_000222 CC(=C)n1c(=O)[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K03 compound treatment 0.251 0.00803 0.43 0.4316 1.0 1149252 ChemDiv2_000223 Cc1nn(Cc2ccccc2)c3ncccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K04 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1194112 ChemDiv2_000224 O=C(CNC(=O)c1ccccc1)OC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K05 compound treatment 0.314 0.071 3.82 3.8171 1.0 1395291 ChemDiv2_000225 CCc1c(C)c2c(C)nn(c3ccccc3)c2nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K06 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1048495 ChemDiv2_000226 CCC(C#N)(C(=O)N)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K07 compound treatment 0.246 0.00303 0.16 0.1629 1.0 1146358 ChemDiv2_000227 CC1(C)CC(CC(C)(C)N1)OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K08 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1983546 ChemDiv2_000228 CCCN(CCC)CC#Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K09 compound treatment 0.454 0.211 11.34 11.3404 1.0 1983547 ChemDiv2_000229 OCCSc1ccc(Oc2ccc(SCCO)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K10 compound treatment 0.293 0.05 2.69 2.6886 1.0 1465090 ChemDiv2_000230 O=C(N1CCNCC1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K11 compound treatment 0.389 0.146 7.85 7.8474 1.0 1354481 ChemDiv2_000231 CCOc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K12 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1453967 ChemDiv2_000232 O=c1oc2ccccc2c(N3CCCCC3)c1CN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K13 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1568464 ChemDiv2_000233 CN(C(=O)c1cccc(N)c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K14 compound treatment 0.29 0.047 2.53 2.5274 1.0 1574016 ChemDiv2_000234 Nc1cccc2C(=O)N(C(=O)c21)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K15 compound treatment 0.278 0.035 1.88 1.8825 1.0 1021191 ChemDiv2_000235 O=c1[nH]c(c([nH]1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K16 compound treatment 0.263 0.02 1.08 1.0764 1.0 1102949 ChemDiv2_000236 CC(O)CCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K17 compound treatment 0.371 0.128 6.88 6.8801 1.0 1039548 ChemDiv2_000237 CCC(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K18 compound treatment 0.248 0.00503 0.27 0.2704 1.0 1012014 ChemDiv2_000238 CCN(CC)Cc1cc(NC(=O)C)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K19 compound treatment 0.376 0.133 7.15 7.1488 1.0 1522165 ChemDiv2_000239 Cc1ccc2[nH]c(=O)nc(c3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K20 compound treatment 0.364 0.121 6.5 6.504 1.0 1107437 ChemDiv2_000240 O=C1C2CCCC1C(NC2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K21 compound treatment 0.494 0.251 13.49 13.4899 1.0 1498046 ChemDiv2_000241 CCN(CC)c1ccc2cc(c3nc4ccccc4c(=O)[nH]3)c(=N)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K22 compound treatment 0.261 0.018 0.97 0.969 1.0 1983548 ChemDiv2_000242 OCn1cnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K23 mock treatment 0.252 0.00903 0.49 0.4853 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 K24 mock treatment 0.255 0.012 0.65 0.6465 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L01 compound treatment 0.258 0.015 0.81 0.8077 1.0 1368927 ChemDiv2_000243 Nc1c(Nc2ccccc2C(=O)O)c3ccccc3oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L02 compound treatment 0.369 0.126 6.77 6.7727 1.0 1487357 ChemDiv2_000244 Brc1ccc(OCC(=O)NCCc2ccccc2)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L03 compound treatment 0.26 0.017 0.92 0.9152 1.0 1983549 ChemDiv2_000245 O=c1n(CCC#N)c2ccccc2n1CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L04 compound treatment 0.271 0.028 1.51 1.5063 1.0 1918544 ChemDiv2_000246 CC(C)(C)Sc1ccc(s1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L05 compound treatment 0.334 0.091 4.89 4.8918 1.0 1983550 ChemDiv2_000247 Clc1nc(SCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L06 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1983551 ChemDiv2_000248 ClCCCC(=O)NC(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L07 compound treatment 0.246 0.00303 0.16 0.1629 1.0 1983552 ChemDiv2_000249 CC1CN=C(NCc2ccccc2)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L08 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1648563 ChemDiv2_000250 O=C(NC1CCN(Cc2ccccc2)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L09 compound treatment 0.281 0.038 2.04 2.0437 1.0 1983553 ChemDiv2_000251 Cc1cc(Cl)ccc1OCCn2cncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L10 compound treatment 0.243 3.12E-5 0.0 0.0017 1.0 1171857 ChemDiv2_000252 OCC1(CO)COC(=N1)C2CCCNC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L11 compound treatment 0.254 0.011 0.59 0.5928 1.0 1709446 ChemDiv2_000253 CC(C(C(C)c1ccccc1)C(=O)O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L12 compound treatment 0.274 0.031 1.67 1.6676 1.0 1648390 ChemDiv2_000254 CC(NC(=O)COc1ccccc1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L13 compound treatment 0.29 0.047 2.53 2.5274 1.0 1930180 ChemDiv2_000255 Cc1cc(SCc2ccccc2)n3ncnc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L14 compound treatment 0.339 0.096 5.16 5.1605 1.0 555 ChemDiv2_000256 Cc1cc2ncc(nc2cc1C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L15 compound treatment 0.259 0.016 0.86 0.8615 1.0 1446066 ChemDiv2_000257 Oc1ccc(Cc2ccc(O)c3ncccc23)c4cccnc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L16 compound treatment 0.39 0.147 7.9 7.9012 1.0 1425182 ChemDiv2_000258 CCCc1ccc(OCC(=O)NCC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L17 compound treatment 0.272 0.029 1.56 1.5601 1.0 1472770 ChemDiv2_000259 CCN1c2cccc3cccc(c23)S1(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L18 compound treatment 0.277 0.034 1.83 1.8288 1.0 1720366 ChemDiv2_000260 CCOC(=O)c1c(sc(=S)n1c2ccccc2)N(C(=O)C)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L19 compound treatment 0.269 0.026 1.4 1.3989 1.0 1983554 ChemDiv2_000261 C=Cn1cccc1c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L20 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1983555 ChemDiv2_000262 CCCC(=O)N1CCS(=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L21 compound treatment 0.353 0.11 5.91 5.9128 1.0 1570672 ChemDiv2_000263 CCS(=O)(=O)c1ccc(O)c(NC(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L22 compound treatment 0.235 -0.00797 -0.43 -0.4282 -1.0 1663911 ChemDiv2_000264 COC(=O)CCC1CCCCC21OCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L23 mock treatment 0.253 0.01 0.54 0.5391 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 L24 mock treatment 0.232 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M01 compound treatment 0.253 0.01 0.54 0.5391 1.0 1257868 ChemDiv2_000265 COC(=O)c1nc(O)c2ccccc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M02 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1004216 ChemDiv2_000266 CN(C)Cc1cc(CN(C)C)c(O)c(CN(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M03 compound treatment 0.248 0.00503 0.27 0.2704 1.0 1522091 ChemDiv2_000267 S=c1oc(nn1CCc2ccncc2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M04 compound treatment 0.254 0.011 0.59 0.5928 1.0 1781277 ChemDiv2_000268 CCOC(=O)c1cnc(=O)[nH]c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M05 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1215184 ChemDiv2_000269 CCOCc1cn(CC(=O)c2ccc(CC)cc2)c(C)nc1=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M06 compound treatment 0.336 0.093 5.0 4.9993 1.0 1325777 ChemDiv2_000270 COc1ccc-2c(c1)C(=NO)c3cc(OC)ccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M07 compound treatment 0.256 0.013 0.7 0.7003 1.0 1178055 ChemDiv2_000271 CCC(C)COC(=O)c1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M08 compound treatment 0.291 0.048 2.58 2.5811 1.0 1983556 ChemDiv2_000272 Oc1cccc2ccc(nc12)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M09 compound treatment 0.246 0.00303 0.16 0.1629 1.0 1983557 ChemDiv2_000273 Clc1ccc(cc1)S(=O)(=O)CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M10 compound treatment 0.55 0.307 16.5 16.4992 1.0 1318405 ChemDiv2_000274 Nc1ccc2oc(nc2c1)c3ccc(cc3)c4nc5cc(N)ccc5o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M11 compound treatment 0.439 0.196 10.53 10.5343 1.0 1115603 ChemDiv2_000275 Oc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M12 compound treatment 0.366 0.123 6.61 6.6114 1.0 1306168 ChemDiv2_000276 OC(c1ccccc1)c2ccc(cc2)C(=O)OCC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M13 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1983558 ChemDiv2_000277 OCC(C1CCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M14 compound treatment 0.403 0.16 8.6 8.5997 1.0 1983559 ChemDiv2_000278 Oc1ccccc1C(=O)Nc2nnc(NC(=O)c3ccccc3O)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M15 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1020567 ChemDiv2_000279 COc1ccccc1C(O)C(=O)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M16 compound treatment 0.387 0.144 7.74 7.7399 1.0 1477453 ChemDiv2_000280 Nc1ccc(cc1)C(=O)OCc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M17 compound treatment 0.254 0.011 0.59 0.5928 1.0 1589440 ChemDiv2_000281 O=C1N(C(=O)c2ccccc12)c3ccc(OCc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M18 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1688249 ChemDiv2_000282 C(CN1CCCCC1)Oc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M19 compound treatment 0.254 0.011 0.59 0.5928 1.0 1252739 ChemDiv2_000283 Cc1ccccc1N2C(=O)C(O)C(O)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M20 compound treatment 0.287 0.044 2.37 2.3661 1.0 1019436 ChemDiv2_000284 CCOC(=O)Nc1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M21 compound treatment 0.266 0.023 1.24 1.2377 1.0 1501827 ChemDiv2_000285 Nc1nc(c(s1)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M22 compound treatment 0.518 0.275 14.78 14.7796 1.0 1983560 ChemDiv2_000286 COCSc1ccc(cc1)C(=O)OCC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M23 mock treatment 0.247 0.00403 0.22 0.2166 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 M24 mock treatment 0.249 0.00603 0.32 0.3241 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N01 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1412213 ChemDiv2_000287 Nc1c(Nc2ccc(cc2)C(=O)O)c3ccccc3oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N02 compound treatment 0.28 0.037 1.99 1.99 1.0 1031087 ChemDiv2_000288 O=C(COc1ccccc1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N03 compound treatment 0.266 0.023 1.24 1.2377 1.0 1914157 ChemDiv2_000289 O=C(C(C(=O)c1ccccc1)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N04 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1692638 ChemDiv2_000290 CC(C)(C)S(=O)(=O)c1ccc(N)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N05 compound treatment 0.488 0.245 13.17 13.1675 1.0 1983561 ChemDiv2_000291 CCCCc1ccc(nc1)c2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N06 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1359818 ChemDiv2_000292 CC(C)CC(C1=C(O)CCCC1=O)C2=C(O)CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N07 compound treatment 0.235 -0.00797 -0.43 -0.4282 -1.0 1983562 ChemDiv2_000293 CC(C)NC1=NCCS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N08 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1983563 ChemDiv2_000294 Cc1nc2n(C)c3ccccc3n2c1C(=O)OCCN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N09 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1370886 ChemDiv2_000295 OC(=O)CCC(=O)OC1N=C(c2ccccc2Cl)c3cc(Br)ccc3NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N10 compound treatment 0.251 0.00803 0.43 0.4316 1.0 1349128 ChemDiv2_000296 COc1ccc(NC(=O)C2CCCNC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N11 compound treatment 0.256 0.013 0.7 0.7003 1.0 1591066 ChemDiv2_000297 O=C(Nc1cccc2C(=O)NC(=O)c21)c3ccc(Oc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N12 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1414534 ChemDiv2_000298 Cc1ccccc1OCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N13 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1778483 ChemDiv2_000299 OCCN(CCO)c1c[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N14 compound treatment 0.248 0.00503 0.27 0.2704 1.0 1983564 ChemDiv2_000300 OCn1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N15 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1570243 ChemDiv2_000301 COc1ccc2cccc(OC)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N16 compound treatment 0.256 0.013 0.7 0.7003 1.0 1504704 ChemDiv2_000302 CC(NC(=O)CCOc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N17 compound treatment 0.232 -0.011 -0.59 -0.5894 -1.0 1027156 ChemDiv2_000303 OC(=O)CC1=C(CCC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N18 compound treatment 0.438 0.195 10.48 10.4806 1.0 1658443 ChemDiv2_000304 Clc1cccc(c1)n2nc3ccc(NC(=O)c4ccco4)cc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N19 compound treatment 0.235 -0.00797 -0.43 -0.4282 -1.0 1004609 ChemDiv2_000305 CC(=O)NC(c1ccccc1)c2c(O)ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N20 compound treatment 0.329 0.086 4.62 4.6231 1.0 1413649 ChemDiv2_000306 CC(NC(=O)COc1cccc(Cl)c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N21 compound treatment 0.301 0.058 3.12 3.1185 1.0 1313535 ChemDiv2_000307 CCS(=O)(=O)c1ccc(O)c(NC(=O)COc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N22 compound treatment 0.319 0.076 4.09 4.0858 1.0 1312287 ChemDiv2_000308 CC1=CCC2(CO)COC(C1C2)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N23 mock treatment 0.253 0.01 0.54 0.5391 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 N24 mock treatment 0.233 -0.00997 -0.54 -0.5357 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O01 compound treatment 0.232 -0.011 -0.59 -0.5894 -1.0 1575040 ChemDiv2_000309 COc1ccc2C(CC(=O)O)OC(=O)c2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O02 compound treatment 0.244 0.00103 0.06 0.0554 1.0 1983565 ChemDiv2_000310 ClCCCC(=O)N1CCCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O03 compound treatment 0.255 0.012 0.65 0.6465 1.0 1983566 ChemDiv2_000311 Cc1cc2c(C)nc(nc2o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O04 compound treatment 0.264 0.021 1.13 1.1302 1.0 1080422 ChemDiv2_000312 COc1ccc(OC)c2c(C)cc(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O05 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1605007 ChemDiv2_000313 CCOC(=O)C1C2CCCC2CNC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O06 compound treatment 0.236 -0.00697 -0.37 -0.3745 -1.0 1186263 ChemDiv2_000314 OC(=O)c1cc(O)ccc1c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O07 compound treatment 0.278 0.035 1.88 1.8825 1.0 1983567 ChemDiv2_000315 Fc1ccccc1C(=O)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O08 compound treatment 0.267 0.024 1.29 1.2914 1.0 1426174 ChemDiv2_000316 COc1ccc2cccc(O)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O09 compound treatment 0.258 0.015 0.81 0.8077 1.0 1230883 ChemDiv2_000317 CC(=O)Nc1ccc(cc1)S(=O)(=O)CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O10 compound treatment 0.502 0.259 13.92 13.9198 1.0 1646903 ChemDiv2_000318 Nc1ccc2nc(CCc3nc4ccc(N)cc4s3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O11 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1983568 ChemDiv2_000319 CCN(CC)c1ccc2ccc(O)cc2[o+]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O12 compound treatment 0.383 0.14 7.52 7.525 1.0 1983569 ChemDiv2_000320 Nc1scc(c1C#N)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O13 compound treatment 0.262 0.019 1.02 1.0227 1.0 1983570 ChemDiv2_000321 COc1c(F)c(F)c(OC)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O14 compound treatment 0.258 0.015 0.81 0.8077 1.0 1983571 ChemDiv2_000322 NS(=N)c1c(O)c2ccccc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O15 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1983572 ChemDiv2_000323 CCCC(O)c1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O16 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1983573 ChemDiv2_000324 OC(=O)c1ccc(cc1)c2nc3cc(Cl)ccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O17 compound treatment 0.442 0.199 10.7 10.6955 1.0 1251944 ChemDiv2_000325 CCCOc1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O18 compound treatment 0.591 0.348 18.7 18.7025 1.0 1209406 ChemDiv2_000326 Nc1nc2ccc(cc2s1)S(=O)(=O)c3ccc4nc(N)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O19 compound treatment 0.35 0.107 5.75 5.7516 1.0 1201051 ChemDiv2_000327 Nc1c(NC2CCCCC2)c3ccccc3oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O20 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1983574 ChemDiv2_000328 CC(N1CCCC1=O)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O21 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1283693 ChemDiv2_000329 CCCC(N1C(=O)c2ccccc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O22 compound treatment 0.532 0.289 15.53 15.5319 1.0 1983575 ChemDiv2_000330 Nc1oc(c(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O23 mock treatment 0.245 0.00203 0.11 0.1092 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 O24 mock treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P01 compound treatment 0.259 0.016 0.86 0.8615 1.0 1724614 ChemDiv2_000331 CCOC(=O)c1ccc(Nc2c(N)c(=O)oc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P02 compound treatment 0.267 0.024 1.29 1.2914 1.0 1122556 ChemDiv2_000332 c1[nH]c2ccccc2c1c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P03 compound treatment 0.238 -0.00497 -0.27 -0.267 -1.0 1983576 ChemDiv2_000333 CN(c1ccccc1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P04 compound treatment 0.25 0.00703 0.38 0.3778 1.0 1478313 ChemDiv2_000334 CCN(CC)Cc1csc(c1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P05 compound treatment 0.245 0.00203 0.11 0.1092 1.0 1983577 ChemDiv2_000335 Cn1cncc1C(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P06 compound treatment 0.252 0.00903 0.49 0.4853 1.0 1921000 ChemDiv2_000336 O/N=C/1\CC(OC21CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P07 compound treatment 0.27 0.027 1.45 1.4526 1.0 1460022 ChemDiv2_000337 OC(=O)c1csc(c1Cc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P08 compound treatment 0.247 0.00403 0.22 0.2166 1.0 1238616 ChemDiv2_000338 C(CN1CCOCC1)N2CCn3c2nc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P09 compound treatment 0.273 0.03 1.61 1.6138 1.0 1983578 ChemDiv2_000339 N#Cc1cn(Cc2ccccc2)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P10 compound treatment 0.24 -0.00297 -0.16 -0.1595 -1.0 1205389 ChemDiv2_000340 CCOC(C(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P11 compound treatment 0.371 0.128 6.88 6.8801 1.0 1983579 ChemDiv2_000341 CCOC(=O)c1nc(oc1N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P12 compound treatment 0.231 -0.012 -0.64 -0.6432 -1.0 1983580 ChemDiv2_000342 C1CSCC(C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P13 compound treatment 0.292 0.049 2.63 2.6348 1.0 1320695 ChemDiv2_000343 Nc1nc(NCc2ccccc2)c(I)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P14 compound treatment 0.237 -0.00597 -0.32 -0.3207 -1.0 1160899 ChemDiv2_000344 O=C(CCc1ccccc1)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P15 compound treatment 0.3 0.057 3.06 3.0647 1.0 1576994 ChemDiv2_000345 COc1ccc2ncc(OC(=O)C)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P16 compound treatment 0.261 0.018 0.97 0.969 1.0 1348969 ChemDiv2_000346 O=C(CCOc1ccccc1)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P17 compound treatment 0.242 -9.69E-4 -0.05 -0.0521 -1.0 1337513 ChemDiv2_000347 CC(C(Cc1cc(C)cc(C)c1)C(=O)Nc2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P18 compound treatment 0.302 0.059 3.17 3.1722 1.0 1207036 ChemDiv2_000348 COC(=O)CN(C(c1ccccc1)c2cc(Br)ccc2NC(=O)c3ccccc3Cl)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P19 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1243850 ChemDiv2_000349 CC(C)c1ccc(C)cc1OCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P20 compound treatment 0.241 -0.00197 -0.11 -0.1058 -1.0 1521483 ChemDiv2_000350 CS(=O)(=O)Nc1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P21 compound treatment 0.28 0.037 1.99 1.99 1.0 1351398 ChemDiv2_000351 Cc1cc(OCC(=O)NCc2ccco2)cc(C)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P22 compound treatment 0.239 -0.00397 -0.21 -0.2133 -1.0 1496592 ChemDiv2_000352 CC(C(Cc1ccc(C)cc1)C(=O)Nc2ccc(F)cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P23 mock treatment 0.236 -0.00697 -0.37 -0.3745 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1369 P24 mock treatment 0.234 -0.00897 -0.48 -0.482 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A01 compound treatment 0.247 -0.0106 -0.57 -0.572 -1.0 1547727 ChemDiv2_000353 Cc1c(N2C(=O)c3ccccc3C2=O)c(=O)n(c4ccccc4)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A02 compound treatment 0.416 0.158 8.51 8.5097 1.0 1294934 ChemDiv2_000354 Nc1nc(cs1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A03 compound treatment 0.241 -0.0166 -0.89 -0.8945 -1.0 1158436 ChemDiv2_000355 COC(=O)Cn1c(=N)n(CCN2CCOCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A04 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1983581 ChemDiv2_000356 COc1ccc(CC(=O)N2CCCC(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A05 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1204779 ChemDiv2_000357 CCN(CC)c1nc2CC(C)(C)CC(=O)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A06 compound treatment 0.282 0.0244 1.31 1.3088 1.0 1685987 ChemDiv2_000358 Cc1cc(F)ccc1NCc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A07 compound treatment 0.422 0.164 8.83 8.8321 1.0 1983582 ChemDiv2_000359 OC(=O)CCC(=O)Nc1ccc-2c(Cc3cc(NC(=O)CCC(=O)O)ccc32)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A08 compound treatment 0.238 -0.0196 -1.06 -1.0557 -1.0 1197925 ChemDiv2_000360 CC1(C)Nc2ccccc2N(CC=C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A09 compound treatment 0.309 0.0514 2.76 2.7597 1.0 1915181 ChemDiv2_000361 COc1ccc(cc1)c2cc(O)[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A10 compound treatment 0.456 0.198 10.66 10.6592 1.0 1430286 ChemDiv2_000362 Nc1ccc2C(=O)N(CCCC(=O)O)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A11 compound treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1522135 ChemDiv2_000363 O=C1OC2(CCCCC2)C(=C1)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A12 compound treatment 0.243 -0.0146 -0.79 -0.787 -1.0 1565570 ChemDiv2_000364 CC(C)CCNc1cc(=O)n(C)c(=O)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A13 compound treatment 0.268 0.0104 0.56 0.5564 1.0 1578633 ChemDiv2_000365 OC(NC(=O)c1cccs1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A14 compound treatment 0.246 -0.0116 -0.63 -0.6258 -1.0 1683936 ChemDiv2_000366 COc1ccc(cc1)C(=O)N(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A15 compound treatment 0.288 0.0304 1.63 1.6312 1.0 1737359 ChemDiv2_000367 CCOC(=O)c1c[nH]c2ccc(C)cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A16 compound treatment 0.264 0.00635 0.34 0.3415 1.0 1127322 ChemDiv2_000368 OC(=O)C(Cc1ccccc1)NC(=O)c2ccccc2NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A17 compound treatment 0.455 0.197 10.61 10.6054 1.0 1467419 ChemDiv2_000369 COCC(=O)c1[nH]c2ccccc2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A18 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1691766 ChemDiv2_000370 NC(=O)c1ccccc1NS(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A19 compound treatment 0.505 0.247 13.29 13.2923 1.0 1657073 ChemDiv2_000371 Cc1cc(=O)[nH]c(SCC(=O)N2CCCc3ccccc23)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A20 compound treatment 0.27 0.0124 0.66 0.6639 1.0 1983583 ChemDiv2_000372 OCCN1CCN(CC#CCC(c2ccccc2)c3ccccc3)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A21 compound treatment 0.309 0.0514 2.76 2.7597 1.0 1161664 ChemDiv2_000373 Clc1cccc(OCC(=O)Oc2ccc3c4CCCc4c(=O)oc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A22 compound treatment 0.286 0.0284 1.52 1.5237 1.0 1283394 ChemDiv2_000374 Nc1nc2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A23 mock treatment 0.268 0.0104 0.56 0.5564 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 A24 mock treatment 0.268 0.0104 0.56 0.5564 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B01 compound treatment 0.409 0.151 8.13 8.1335 1.0 1361846 ChemDiv2_000375 Cn1c(=O)n(CCOc2ccc(Cl)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B02 compound treatment 0.268 0.0104 0.56 0.5564 1.0 1307805 ChemDiv2_000376 Cc1ccccc1Nc2cccc3nonc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B03 compound treatment 0.308 0.0504 2.71 2.706 1.0 1951703 ChemDiv2_000377 OC(=O)c1ccc(cc1)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B04 compound treatment 0.268 0.0104 0.56 0.5564 1.0 1282349 ChemDiv2_000378 CC(O)(CC1C(C)(O)CCC2C(C)(C)CCCC12C)C=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B05 compound treatment 0.237 -0.0206 -1.11 -1.1094 -1.0 1361307 ChemDiv2_000379 OCc1cc(=O)c(O)c(CN2CCCC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B06 compound treatment 0.29 0.0324 1.74 1.7387 1.0 1221558 ChemDiv2_000380 COc1ccccc1N2CCN(Cc3cc(Cl)c(O)c4ncccc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B07 compound treatment 0.302 0.0444 2.38 2.3835 1.0 1343104 ChemDiv2_000381 O=c1[nH][nH]c(=O)c2cc(ccc12)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B08 compound treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1947214 ChemDiv2_000382 CSC1=NC2(CC31C=CC(=O)C=C3)CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B09 compound treatment 0.374 0.116 6.25 6.2527 1.0 1983584 ChemDiv2_000383 Cc1ccc(cc1)C2C3=C(NC4=C2C(=O)CCC4)c5ccccc5C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B10 compound treatment 0.243 -0.0146 -0.79 -0.787 -1.0 1205165 ChemDiv2_000384 O=C(Cn1c(=O)n(CC(=O)NC2CCCCC2)c3ccccc13)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B11 compound treatment 0.262 0.00435 0.23 0.234 1.0 1940744 ChemDiv2_000385 ON(C(=O)c1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B12 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1311182 ChemDiv2_000386 Nc1nonc1c2nnnn2CC(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B13 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1983585 ChemDiv2_000387 Cc1cc(=O)n(C)c(=O)n1CCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B14 compound treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1515818 ChemDiv2_000388 COc1ccc(CNCC2(O)CCOC(C)(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B15 compound treatment 0.369 0.111 5.98 5.984 1.0 1657991 ChemDiv2_000389 O=C(CSc1nc2CCCCCc2cc1C#N)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B16 compound treatment 0.276 0.0184 0.99 0.9864 1.0 1983586 ChemDiv2_000390 CC1CC(=CC(C)C1COC(=O)CN2CCCC2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B17 compound treatment 0.271 0.0134 0.72 0.7177 1.0 1732968 ChemDiv2_000391 OC1(CCN(Cc2ccccc2)CC1C(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B18 compound treatment 0.271 0.0134 0.72 0.7177 1.0 1012425 ChemDiv2_000392 C(Nc1ccccc1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B19 compound treatment 0.423 0.165 8.89 8.8858 1.0 1165707 ChemDiv2_000393 Clc1cccc(c1)C(=O)NCC2(CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B20 compound treatment 0.255 -0.00265 -0.14 -0.1421 -1.0 1440985 ChemDiv2_000394 Nc1ncc2C(=O)CC(Cc2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B21 compound treatment 0.259 0.00135 0.07 0.0728 1.0 1172532 ChemDiv2_000395 CCOC(=O)C(C#N)C(C1CCOC(C)(C)C1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B22 compound treatment 0.231 -0.0266 -1.43 -1.4319 -1.0 1663357 ChemDiv2_000396 CCCc1nc2oc3c(c4ccccc4)c(C(=O)O)c(C)nc3c2c5CC(C)(C)OCc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B23 mock treatment 0.299 0.0414 2.22 2.2223 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 B24 mock treatment 0.254 -0.00365 -0.2 -0.1959 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C01 compound treatment 0.243 -0.0146 -0.79 -0.787 -1.0 1036029 ChemDiv2_000397 OC(=O)CCC(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C02 compound treatment 0.243 -0.0146 -0.79 -0.787 -1.0 1398179 ChemDiv2_000398 OC(=O)C(CC(=O)Nc1ccccc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C03 compound treatment 0.278 0.0204 1.09 1.0938 1.0 1048950 ChemDiv2_000399 OC(c1nc2ccccc2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C04 compound treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1274843 ChemDiv2_000400 CCOC(=O)c1c(N)sc2c1CC(C)(C)NC2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C05 compound treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1495550 ChemDiv2_000401 CCN(CC)c1nc2CC(C)(C)CNC(=O)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C06 compound treatment 0.333 0.0754 4.05 4.0494 1.0 1737432 ChemDiv2_000402 COC(=O)C(C(=O)OC)c1cc(Br)c2noc3-c4ccccc4C(=O)c1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C07 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1665617 ChemDiv2_000403 COc1cc(NC(=O)c2ccc3C(=O)N(C(=O)c3c2)c4cccc(C)c4C)c(cc1OC)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C08 compound treatment 0.247 -0.0106 -0.57 -0.572 -1.0 1983587 ChemDiv2_000404 CC(=O)N1c2ccccc2NC(=O)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C09 compound treatment 0.353 0.0954 5.12 5.1242 1.0 1644147 ChemDiv2_000405 CCN(CC)c1ccc2NCCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C10 compound treatment 0.423 0.165 8.89 8.8858 1.0 1184897 ChemDiv2_000406 COc1ccc(OC(C)C(=O)Nc2ccc3OCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C11 compound treatment 0.394 0.136 7.33 7.3274 1.0 1983588 ChemDiv2_000407 CNc1nnc(Cl)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C12 compound treatment 0.297 0.0394 2.11 2.1148 1.0 1480470 ChemDiv2_000408 O=C(Nc1ccccc1)c2cc(cs2)S(=O)(=O)Nc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C13 compound treatment 0.286 0.0284 1.52 1.5237 1.0 1497038 ChemDiv2_000409 C=CCOc1ccc(cc1)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C14 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1159196 ChemDiv2_000410 OC(=O)C1CCC(=O)CC1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C15 compound treatment 0.433 0.175 9.42 9.4232 1.0 1325353 ChemDiv2_000411 CCOC(=O)c1c[nH]c2c(ccc3ccccc32)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C16 compound treatment 0.262 0.00435 0.23 0.234 1.0 1040440 ChemDiv2_000412 Clc1c(cnn(c2ccccc2)c1=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C17 compound treatment 0.268 0.0104 0.56 0.5564 1.0 1345446 ChemDiv2_000413 Cc1[nH]c2ccc(C)cc2c1CCC(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C18 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1383530 ChemDiv2_000414 Cc1ccc(NS(=O)(=O)Cc2ccccc2)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C19 compound treatment 0.497 0.239 12.86 12.8624 1.0 1787964 ChemDiv2_000415 CCN(CC)c1ccc(cc1)c2cc(C#N)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C20 compound treatment 0.255 -0.00265 -0.14 -0.1421 -1.0 1983589 ChemDiv2_000416 CC(C)C(O)(CC#CCN1CCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C21 compound treatment 0.499 0.241 12.97 12.9699 1.0 1642324 ChemDiv2_000417 COC(=O)c1cc(Cl)c(NC(=O)c2ccco2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C22 compound treatment 0.259 0.00135 0.07 0.0728 1.0 1269277 ChemDiv2_000418 COC(=O)Cn1c(=N)n(CC=C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C23 mock treatment 0.264 0.00635 0.34 0.3415 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 C24 mock treatment 0.249 -0.00865 -0.46 -0.4646 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D01 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1983590 ChemDiv2_000419 Cc1nc2ccccc2n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D02 compound treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1263988 ChemDiv2_000420 O=C(C1CN2CCC1CC2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D03 compound treatment 0.598 0.34 18.29 18.29 1.0 1422531 ChemDiv2_000421 Nc1cccc(c1)c2nc3cc(ccc3[nH]2)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D04 compound treatment 0.245 -0.0126 -0.68 -0.6795 -1.0 1983591 ChemDiv2_000422 O=C(NCCCn1ccnc1)C2CCC(=O)N2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D05 compound treatment 0.423 0.165 8.89 8.8858 1.0 1983592 ChemDiv2_000423 O=S(=O)(c1cccs1)n2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D06 compound treatment 0.371 0.113 6.09 6.0915 1.0 1317035 ChemDiv2_000424 CCN(CC)C(=O)CSc1nc2CCCc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D07 compound treatment 0.311 0.0534 2.87 2.8672 1.0 1255957 ChemDiv2_000425 CC1C(NC(C(C)C1=O)c2ccc3OCOc3c2)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D08 compound treatment 0.238 -0.0196 -1.06 -1.0557 -1.0 1596831 ChemDiv2_000426 CCOC(=O)CC(=O)NC1(Cc2ccc(O)cc2)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D09 compound treatment 0.321 0.0634 3.4 3.4046 1.0 1983593 ChemDiv2_000427 Brc1ccc(cc1)C2C3=C(NC4=C2C(=O)CCC4)c5ccccc5C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D10 compound treatment 0.242 -0.0156 -0.84 -0.8407 -1.0 1493492 ChemDiv2_000428 CCC(=O)N1CC2(OC3CC2CC41CCCCC4)C=C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D11 compound treatment 0.424 0.166 8.94 8.9396 1.0 1297201 ChemDiv2_000429 CC(=O)Nc1ncc2C(=O)CC(Cc2n1)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D12 compound treatment 0.346 0.0884 4.75 4.748 1.0 1704176 ChemDiv2_000430 COC(=O)c1ccccc1NC(=O)COC(=O)c2ccn(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D13 compound treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1598548 ChemDiv2_000431 CC1(C)C(OC(=O)C(C)(C)C1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D14 compound treatment 0.244 -0.0136 -0.73 -0.7333 -1.0 1983594 ChemDiv2_000432 CC(CCC=C(C)C)N1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D15 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1100916 ChemDiv2_000433 CC(=O)N=c1sccn1CC(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D16 compound treatment 0.27 0.0124 0.66 0.6639 1.0 1983595 ChemDiv2_000434 CC1CC(=CC(C)C1COC(=O)CN2CCOCC2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D17 compound treatment 0.263 0.00535 0.29 0.2878 1.0 1736302 ChemDiv2_000435 COc1ccc2[nH]cc(CCC(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D18 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1356942 ChemDiv2_000436 COc1ccc(CNCc2ccc(OC)c(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D19 compound treatment 0.266 0.00835 0.45 0.449 1.0 1249212 ChemDiv2_000437 O=C(NCC1(CCOCC1)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D20 compound treatment 0.262 0.00435 0.23 0.234 1.0 1358820 ChemDiv2_000438 COC(=O)C(CCCN1C(=O)c2ccccc2C1=O)(NC(=O)C)c3nnn(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D21 compound treatment 0.288 0.0304 1.63 1.6312 1.0 1368287 ChemDiv2_000439 CCOC(=O)C(C#N)C(Cc1ccccc1)C2CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D22 compound treatment 0.266 0.00835 0.45 0.449 1.0 1983596 ChemDiv2_000440 CN(C)CCNC(=O)c1ccc(/C=N/O)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D23 mock treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 D24 mock treatment 0.244 -0.0136 -0.73 -0.7333 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E01 compound treatment 0.303 0.0454 2.44 2.4373 1.0 1587902 ChemDiv2_000441 CCN(CC)c1ccc(cc1)C(=O)OCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E02 compound treatment 0.469 0.211 11.36 11.3578 1.0 1463031 ChemDiv2_000442 CCC(=O)Nc1ccc2nn(nc2c1)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E03 compound treatment 0.271 0.0134 0.72 0.7177 1.0 1070066 ChemDiv2_000443 CC(=O)N1C(=O)c2cccc3cccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E04 compound treatment 0.263 0.00535 0.29 0.2878 1.0 1983597 ChemDiv2_000444 N/C(=N\O)/CSc1nc(c(o1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E05 compound treatment 0.249 -0.00865 -0.46 -0.4646 -1.0 1271809 ChemDiv2_000445 CN(C)CCNC(=O)c1ccc(cc1)S(=O)(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E06 compound treatment 0.308 0.0504 2.71 2.706 1.0 1686458 ChemDiv2_000446 Cc1cccc(c1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E07 compound treatment 0.244 -0.0136 -0.73 -0.7333 -1.0 1460778 ChemDiv2_000447 Cc1cc2C3C=CCC3CN4C(C5CC=CC5c(c1)c42)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E08 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1573170 ChemDiv2_000448 CC(=O)N1c2ccccc2N(Cc3ccc(C)cc3C)C(=O)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E09 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1203093 ChemDiv2_000449 CCN1CCCc2cc(O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E10 compound treatment 0.463 0.205 11.04 11.0353 1.0 1290374 ChemDiv2_000450 CCCOC(=O)c1cccc(NC(=O)OCC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E11 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1983598 ChemDiv2_000451 CC(C)OC(=O)Nc1nonc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E12 compound treatment 0.436 0.178 9.58 9.5844 1.0 1983599 ChemDiv2_000452 OC(=O)c1ccccc1NC(=O)c2cc(cs2)S(=O)(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E13 compound treatment 0.32 0.0624 3.35 3.3508 1.0 1983600 ChemDiv2_000453 CCCc1cc(O)n(n1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E14 compound treatment 0.261 0.00335 0.18 0.1803 1.0 1983601 ChemDiv2_000454 CC1(C)CC(=O)C=C(C1)NCCCN2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E15 compound treatment 0.274 0.0164 0.88 0.8789 1.0 1983602 ChemDiv2_000455 OC(CC#CCN1CCOCC1)(C2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E16 compound treatment 0.255 -0.00265 -0.14 -0.1421 -1.0 1983603 ChemDiv2_000456 Clc1c(cn[nH]c1=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E17 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1983604 ChemDiv2_000457 CS(=O)(=O)c1nncn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E18 compound treatment 0.303 0.0454 2.44 2.4373 1.0 1784938 ChemDiv2_000458 O=S(=O)(Cc1ccccc1)Nc2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E19 compound treatment 0.389 0.131 7.06 7.0587 1.0 1983605 ChemDiv2_000459 NC(=O)c1cc(no1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E20 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1582091 ChemDiv2_000460 OC(=O)c1ccccc1c2ccccc2C(=O)NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E21 compound treatment 0.378 0.12 6.47 6.4676 1.0 1296702 ChemDiv2_000461 CCC(=O)c1ccc(OC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E22 compound treatment 0.283 0.0254 1.36 1.3625 1.0 1579506 ChemDiv2_000462 COC(=O)c1c(C)nc2n(CCN3CCCCC3)c4ccccc4n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E23 mock treatment 0.254 -0.00365 -0.2 -0.1959 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 E24 mock treatment 0.26 0.00235 0.13 0.1265 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F01 compound treatment 0.451 0.193 10.39 10.3905 1.0 1494593 ChemDiv2_000463 COc1ccc(NC(=O)c2c(C)c(sc2N)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F02 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1226368 ChemDiv2_000464 CC(=O)NC1CCCc2c1[nH]c3ccc(C)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F03 compound treatment 0.524 0.266 14.31 14.3134 1.0 1491426 ChemDiv2_000465 CN1C(=O)c2ccc(cc2C1=O)S(=O)(=O)c3ccc(cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F04 compound treatment 0.239 -0.0186 -1.0 -1.002 -1.0 1147426 ChemDiv2_000466 CCOC(=O)C(C1CCCCC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F05 compound treatment 0.243 -0.0146 -0.79 -0.787 -1.0 1530242 ChemDiv2_000467 COc1ccc(cc1C(=O)O)S(=O)(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F06 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1262559 ChemDiv2_000468 CCOC(=O)C1(NC(=O)CC1c2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F07 compound treatment 0.271 0.0134 0.72 0.7177 1.0 1553735 ChemDiv2_000469 CCOC(=O)C(C#N)C(c1ccc2OCOc2c1)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F08 compound treatment 0.326 0.0684 3.67 3.6732 1.0 1650563 ChemDiv2_000470 NC1=C(C#N)C2=CCCCC2C(c3ccco3)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F09 compound treatment 0.255 -0.00265 -0.14 -0.1421 -1.0 1426796 ChemDiv2_000471 COc1ccccc1C(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F10 compound treatment 0.269 0.0114 0.61 0.6102 1.0 1584727 ChemDiv2_000472 c1ccc(cc1)c2nc3nonc3c4nc5ccccc5n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F11 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1983606 ChemDiv2_000473 OC(=O)c1cc2CCCCc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F12 compound treatment 0.381 0.123 6.63 6.6288 1.0 1412128 ChemDiv2_000474 Brc1ccccc1OCC(=O)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F13 compound treatment 0.412 0.154 8.29 8.2947 1.0 1185829 ChemDiv2_000475 CCN(CC)c1ccc2cc(NC(=O)CCC(=O)O)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F14 compound treatment 0.254 -0.00365 -0.2 -0.1959 -1.0 1577024 ChemDiv2_000476 Oc1ccccc1CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F15 compound treatment 0.308 0.0504 2.71 2.706 1.0 1983607 ChemDiv2_000477 CCC1CCCCN1C(=O)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F16 compound treatment 0.278 0.0204 1.09 1.0938 1.0 1983608 ChemDiv2_000478 O=C(CN1CCOCC1)OCCCC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F17 compound treatment 0.405 0.147 7.92 7.9185 1.0 1159301 ChemDiv2_000479 CCOC(=O)c1sc2nc3CCCn3c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F18 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1259003 ChemDiv2_000480 C(NCc1ccc2OCOc2c1)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F19 compound treatment 0.502 0.244 13.13 13.1311 1.0 1173041 ChemDiv2_000481 C=CCOc1ccc(cc1)C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F20 compound treatment 0.461 0.203 10.93 10.9279 1.0 1340152 ChemDiv2_000482 CCC(=O)Nc1ccc2oc(nc2c1)c3ccccc3Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F21 compound treatment 0.308 0.0504 2.71 2.706 1.0 1435349 ChemDiv2_000483 CC(=O)N(CCC(C1CCOC(C)(C)C1)c2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F22 compound treatment 0.281 0.0234 1.26 1.255 1.0 1983609 ChemDiv2_000484 OCCNC(=O)c1ccc(/C=N/O)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F23 mock treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 F24 mock treatment 0.264 0.00635 0.34 0.3415 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G01 compound treatment 0.259 0.00135 0.07 0.0728 1.0 1221210 ChemDiv2_000485 COc1ccc(cc1)C(=O)c2cnc(C(C)C)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G02 compound treatment 0.531 0.273 14.69 14.6895 1.0 1169459 ChemDiv2_000486 CCOc1ccc(cc1)c2nc3cc(N)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G03 compound treatment 0.273 0.0154 0.83 0.8251 1.0 1983610 ChemDiv2_000487 CCOC(=O)Nc1ccc(C)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G04 compound treatment 0.35 0.0924 4.96 4.963 1.0 1738630 ChemDiv2_000488 Cc1ccc(cc1)S(=O)(=O)CCC(=O)c2ccc(O)cc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G05 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1317333 ChemDiv2_000489 COc1ccc2oc(=O)c(NC(=O)C3CCCCC3)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G06 compound treatment 0.284 0.0264 1.42 1.4163 1.0 1127866 ChemDiv2_000490 OC(=O)CCC(=O)Nc1cccc(c1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G07 compound treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1983611 ChemDiv2_000491 CC(=O)N(CCC#N)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G08 compound treatment 0.3 0.0424 2.28 2.2761 1.0 1090074 ChemDiv2_000492 O=c1[nH]n(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G09 compound treatment 0.264 0.00635 0.34 0.3415 1.0 1212463 ChemDiv2_000493 CC12CCOC2N(c3ccccc31)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G10 compound treatment 0.265 0.00735 0.4 0.3952 1.0 1983612 ChemDiv2_000494 OC(=O)CCCC(=O)NC1=NCCS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G11 compound treatment 0.452 0.194 10.44 10.4442 1.0 1203650 ChemDiv2_000495 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G12 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1925878 ChemDiv2_000496 Cc1nnc(SCN2C(=O)c3ccccc3C2=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G13 compound treatment 0.281 0.0234 1.26 1.255 1.0 1714201 ChemDiv2_000497 COc1ccc(C(=O)NCCN2CCOCC2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G14 compound treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1016462 ChemDiv2_000498 CCOC(=O)C(N)C(O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G15 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1983613 ChemDiv2_000499 CN1CCN(CC#CCC(O)(C2CCCC2)c3ccccc3)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G16 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1983614 ChemDiv2_000500 CN1CCN(CC1)c2cn[nH]c(=O)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G17 compound treatment 0.311 0.0534 2.87 2.8672 1.0 1983615 ChemDiv2_000501 COC(=O)CCC(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G18 compound treatment 0.274 0.0164 0.88 0.8789 1.0 1983616 ChemDiv2_000502 C(Cc1ccccc1)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G19 compound treatment 0.41 0.152 8.19 8.1872 1.0 1787971 ChemDiv2_000503 CCOc1ccc(cc1)c2cc(on2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G20 compound treatment 0.295 0.0374 2.01 2.0074 1.0 1413627 ChemDiv2_000504 COc1ccc(cc1)c2occ(C(=O)O)c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G21 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1937289 ChemDiv2_000505 Cc1nc(C)n(C)c(=O)c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G22 compound treatment 0.264 0.00635 0.34 0.3415 1.0 1482231 ChemDiv2_000506 Cn1c(=N)n(CCO)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G23 mock treatment 0.268 0.0104 0.56 0.5564 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 G24 mock treatment 0.264 0.00635 0.34 0.3415 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H01 compound treatment 0.244 -0.0136 -0.73 -0.7333 -1.0 1280941 ChemDiv2_000507 CCCN(CCC)C(=O)c1ccccc1NC(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H02 compound treatment 0.296 0.0384 2.06 2.0611 1.0 1181652 ChemDiv2_000508 O=C1NCC2=C1C(Nc3ccccc3N2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H03 compound treatment 0.274 0.0164 0.88 0.8789 1.0 1983617 ChemDiv2_000509 C=CCn1c(=S)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H04 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1179593 ChemDiv2_000510 CCOC(=O)C(Cc1ccccc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H05 compound treatment 0.249 -0.00865 -0.46 -0.4646 -1.0 1983618 ChemDiv2_000511 Cc1[nH]c(=O)n(c(=O)c1Cl)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H06 compound treatment 0.456 0.198 10.66 10.6592 1.0 1480273 ChemDiv2_000512 CCOC(=O)C(C)Oc1cc2oc(=O)c3CCCc3c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H07 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1157637 ChemDiv2_000513 COC(=O)c1ccc(CN(C)C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H08 compound treatment 0.343 0.0854 4.59 4.5868 1.0 1431536 ChemDiv2_000514 CCN(CC)C(=O)c1c(oc2ccc(O)cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H09 compound treatment 0.236 -0.0216 -1.16 -1.1632 -1.0 1071977 ChemDiv2_000515 CC1(C)COC(=N1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H10 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1378864 ChemDiv2_000516 O=C1CCCCC(=O)c2ccccc2N1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H11 compound treatment 0.293 0.0354 1.9 1.8999 1.0 1983619 ChemDiv2_000517 COc1ccc(CN2CCC(=CC2)/C=C/c3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H12 compound treatment 0.269 0.0114 0.61 0.6102 1.0 1983620 ChemDiv2_000518 CN(C)c1cc(N)c2cc(Cl)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H13 compound treatment 0.494 0.236 12.7 12.7012 1.0 1663751 ChemDiv2_000519 Fc1ccc(cc1)C(=O)c2ccc(cc2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H14 compound treatment 0.325 0.0674 3.62 3.6195 1.0 1983621 ChemDiv2_000520 Oc1ccccc1C/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H15 compound treatment 0.263 0.00535 0.29 0.2878 1.0 1628514 ChemDiv2_000521 CC(Oc1ccccc1)C(=O)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H16 compound treatment 0.262 0.00435 0.23 0.234 1.0 1983622 ChemDiv2_000522 O=C(CN1CCCC1)OCCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H17 compound treatment 0.383 0.125 6.74 6.7363 1.0 1983623 ChemDiv2_000523 CCOC(=O)c1c2CCCn2c3ccc(O)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H18 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1983624 ChemDiv2_000524 OCc1ccc(o1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H19 compound treatment 0.309 0.0514 2.76 2.7597 1.0 1605435 ChemDiv2_000525 Cc1ccc(cc1)C(=O)c2cncc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H20 compound treatment 0.313 0.0554 2.97 2.9747 1.0 1451788 ChemDiv2_000526 CCCCC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(C)cc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H21 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1210459 ChemDiv2_000527 CC(C)C1(CN(CC2(CN(C1)C(=O)c3ccccc3)C(C)C)C(=O)c4ccccc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H22 compound treatment 0.247 -0.0106 -0.57 -0.572 -1.0 1983625 ChemDiv2_000528 C/C(=N\O)/C(=O)NCCN1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H23 mock treatment 0.265 0.00735 0.4 0.3952 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 H24 mock treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I01 compound treatment 0.266 0.00835 0.45 0.449 1.0 1584920 ChemDiv2_000529 COc1ccc(cc1)C(O)c2nccn2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I02 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1636387 ChemDiv2_000530 Cc1ccc(C)n1c2cc(ccc2C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I03 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1677614 ChemDiv2_000531 O=C1CC(Nc2ccc3ccccc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I04 compound treatment 0.299 0.0414 2.22 2.2223 1.0 1348912 ChemDiv2_000532 COc1ccc(cc1)S(=O)(=O)CCc2nnc(o2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I05 compound treatment 0.249 -0.00865 -0.46 -0.4646 -1.0 1356507 ChemDiv2_000533 OC(=O)C(CC(=O)NCc1ccccc1)C2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I06 compound treatment 0.28 0.0224 1.2 1.2013 1.0 1505137 ChemDiv2_000534 O=C1CCC(=O)N1c2cccc(c2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I07 compound treatment 0.324 0.0664 3.57 3.5658 1.0 1555506 ChemDiv2_000535 CCCCc1ccc(cc1)C(=O)Nc2cc3cccc(OC)c3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I08 compound treatment 0.259 0.00135 0.07 0.0728 1.0 1414103 ChemDiv2_000536 Cc1nc(c2ccccc2O)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I09 compound treatment 0.27 0.0124 0.66 0.6639 1.0 1545379 ChemDiv2_000537 CC12CCOC2N(Cc3ccccc3)c4ccccc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I10 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1094400 ChemDiv2_000538 COc1ccc(cc1OC)c2nn(C)c3nc(=O)n(C)c(=O)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I11 compound treatment 0.469 0.211 11.36 11.3578 1.0 1250668 ChemDiv2_000539 Oc1ccc(Cn2cnc3ccccc23)c4cccnc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I12 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1178754 ChemDiv2_000540 COC(=O)c1ccccc1NC(=O)Cn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I13 compound treatment 0.367 0.109 5.88 5.8765 1.0 1447077 ChemDiv2_000541 COc1ccc(C(=O)NCc2ccco2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I14 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1983626 ChemDiv2_000542 CN(C)CCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I15 compound treatment 0.282 0.0244 1.31 1.3088 1.0 1685781 ChemDiv2_000543 OC(=O)CCSc1nnnn1C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I16 compound treatment 0.278 0.0204 1.09 1.0938 1.0 1983627 ChemDiv2_000544 Clc1c(cn[nH]c1=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I17 compound treatment 0.265 0.00735 0.4 0.3952 1.0 1616293 ChemDiv2_000545 CN(C)Cc1c(O)ccc2occ(C(=O)c3ccc(F)cc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I18 compound treatment 0.288 0.0304 1.63 1.6312 1.0 1983628 ChemDiv2_000546 CNc1csc(C)c(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I19 compound treatment 0.346 0.0884 4.75 4.748 1.0 1983629 ChemDiv2_000547 NC(=O)c1cc(no1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I20 compound treatment 0.295 0.0374 2.01 2.0074 1.0 1442644 ChemDiv2_000548 CN(C)c1ccnc2sc3c(ncnc3c12)N(CCO)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I21 compound treatment 0.291 0.0334 1.79 1.7924 1.0 1783632 ChemDiv2_000549 CCc1nc(cc2cc(OC)c(OC)cc12)c3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I22 compound treatment 0.262 0.00435 0.23 0.234 1.0 1158974 ChemDiv2_000550 CCCCn1c(=N)n(CCO)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I23 mock treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 I24 mock treatment 0.265 0.00735 0.4 0.3952 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J01 compound treatment 0.297 0.0394 2.11 2.1148 1.0 1373383 ChemDiv2_000551 CCCNC(=O)c1ccccc1NC(=O)C(C)Oc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J02 compound treatment 0.274 0.0164 0.88 0.8789 1.0 1021955 ChemDiv2_000552 COC(=O)C1c2ccccc2-c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J03 compound treatment 0.255 -0.00265 -0.14 -0.1421 -1.0 1983630 ChemDiv2_000553 CCc1nn2c(C)cc(C)nc2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J04 compound treatment 0.239 -0.0186 -1.0 -1.002 -1.0 1983631 ChemDiv2_000554 CN(C)S(=O)(=O)Nc1cccc(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J05 compound treatment 0.262 0.00435 0.23 0.234 1.0 1338323 ChemDiv2_000555 CC(C)OCC1Cn2c(O1)nc3n(C)c(=O)n(C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J06 compound treatment 0.425 0.167 8.99 8.9933 1.0 1213369 ChemDiv2_000556 COC(=O)C(C)Oc1cc2oc(=O)c3CCCCc3c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J07 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1983632 ChemDiv2_000557 CCOc1cc(CNCCc2ccccc2)ccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J08 compound treatment 0.339 0.0814 4.37 4.3718 1.0 1192088 ChemDiv2_000558 CNC(=O)c1c(oc2ccc(O)cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J09 compound treatment 0.318 0.0604 3.24 3.2433 1.0 1439388 ChemDiv2_000559 CC(C)CC(=O)Nc1ncnc2CC(C)(C)CC(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J10 compound treatment 0.267 0.00935 0.5 0.5027 1.0 1261890 ChemDiv2_000560 O=C1CCc2c1[nH]c3ccc(OCc4ccccc4)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J11 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1458366 ChemDiv2_000561 OC(=O)CCC(=O)N(Cc1ccccc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J12 compound treatment 0.261 0.00335 0.18 0.1803 1.0 1638153 ChemDiv2_000562 O=C(Nc1ccccc1C(=O)N2CCc3ccccc3C2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J13 compound treatment 0.265 0.00735 0.4 0.3952 1.0 1925341 ChemDiv2_000563 Nc1cc(nn1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J14 compound treatment 0.276 0.0184 0.99 0.9864 1.0 1983633 ChemDiv2_000564 C/C=C/C1OCC2(CO)C(C)C=C(C)C1C2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J15 compound treatment 0.502 0.244 13.13 13.1311 1.0 1666556 ChemDiv2_000565 C1Cc2[nH]c(nc2-c3nonc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J16 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1725187 ChemDiv2_000566 COC(=O)c1ccc(CN2CCOCC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J17 compound treatment 0.371 0.113 6.09 6.0915 1.0 1782378 ChemDiv2_000567 CCOC(=O)c1c2CCCn2c3ccc(OC(=O)C)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J18 compound treatment 0.328 0.0704 3.78 3.7807 1.0 1417181 ChemDiv2_000568 CC(=O)Nc1cccc(c2nc3cc(C)ccc3o2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J19 compound treatment 0.268 0.0104 0.56 0.5564 1.0 1404149 ChemDiv2_000569 Cc1ccc(cc1)C(CC#N)C2CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J20 compound treatment 0.307 0.0494 2.65 2.6522 1.0 1983634 ChemDiv2_000570 Cc1ccc(NC(=O)CCC2CC(C)(C)OC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J21 compound treatment 0.249 -0.00865 -0.46 -0.4646 -1.0 1178743 ChemDiv2_000571 CC1(C)CC(CC(=O)O)(CCO1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J22 compound treatment 0.511 0.253 13.61 13.6148 1.0 1983635 ChemDiv2_000572 O=C(N1CCC(C1)c2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J23 mock treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 J24 mock treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K01 compound treatment 0.265 0.00735 0.4 0.3952 1.0 1343911 ChemDiv2_000573 CC(C)n1c(nc2ccccc12)C(O)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K02 compound treatment 0.247 -0.0106 -0.57 -0.572 -1.0 1581708 ChemDiv2_000574 Cc1ccc(C)n1c2ccc(CC(=O)O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K03 compound treatment 0.245 -0.0126 -0.68 -0.6795 -1.0 1447489 ChemDiv2_000575 OC(C#CCN1CCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K04 compound treatment 0.254 -0.00365 -0.2 -0.1959 -1.0 1983636 ChemDiv2_000576 COc1cccc(CNCCc2cccc(F)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K05 compound treatment 0.262 0.00435 0.23 0.234 1.0 1528655 ChemDiv2_000577 CC(=O)Nc1[nH]c2ccccc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K06 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1666738 ChemDiv2_000578 CNC(=O)Oc1ccc2sc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K07 compound treatment 0.284 0.0264 1.42 1.4163 1.0 1983637 ChemDiv2_000579 Oc1cc(n[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K08 compound treatment 0.262 0.00435 0.23 0.234 1.0 1923368 ChemDiv2_000580 CC(C)(C)C1(O)CC(=NO1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K09 compound treatment 0.291 0.0334 1.79 1.7924 1.0 1174390 ChemDiv2_000581 NC(=O)c1cccc(NC(=O)c2ccccc2I)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K10 compound treatment 0.322 0.0644 3.46 3.4583 1.0 1560466 ChemDiv2_000582 CCn1nc(nc2c(=O)n(C)c(=O)nc12)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K11 compound treatment 0.266 0.00835 0.45 0.449 1.0 1433185 ChemDiv2_000583 COC(=O)Nc1ccc(cc1)S(=O)(=O)N(CC=C)c2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K12 compound treatment 0.517 0.259 13.94 13.9372 1.0 1457108 ChemDiv2_000584 O=C(Nc1ccc2nn(nc2c1)c3ccccc3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K13 compound treatment 0.438 0.18 9.69 9.6919 1.0 1552261 ChemDiv2_000585 CCOc1ccc(cc1)C(=O)N2CCC(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K14 compound treatment 0.274 0.0164 0.88 0.8789 1.0 1983638 ChemDiv2_000586 COc1ccc(NC(=O)CSC2=NC(=O)CC(=N2)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K15 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1009622 ChemDiv2_000587 CCOc1ccccc1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K16 compound treatment 0.319 0.0614 3.3 3.2971 1.0 1681878 ChemDiv2_000588 COC(=O)C1=C(N)Oc2c(C1c3cccnc3)c(=O)oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K17 compound treatment 0.36 0.102 5.5 5.5003 1.0 1578482 ChemDiv2_000589 O=C1CN=C(c2oc3ccccc3c2N1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K18 compound treatment 0.375 0.117 6.31 6.3064 1.0 1983639 ChemDiv2_000590 Nc1c(C#N)c(=N)sn1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K19 compound treatment 0.417 0.159 8.56 8.5634 1.0 1983640 ChemDiv2_000591 CCOC(=O)c1cc(no1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K20 compound treatment 0.291 0.0334 1.79 1.7924 1.0 1238895 ChemDiv2_000592 Cc1c(C#N)c(N)c(C(=O)c2ccccc2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K21 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1243334 ChemDiv2_000593 CC1=C(C)CC(C(C1)C(=O)O)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K22 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1127269 ChemDiv2_000594 OCCn1c(=N)n(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K23 mock treatment 0.263 0.00535 0.29 0.2878 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 K24 mock treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L01 compound treatment 0.534 0.276 14.85 14.8507 1.0 1213316 ChemDiv2_000595 CCCc1cc(=O)n2nc(cc2[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L02 compound treatment 0.262 0.00435 0.23 0.234 1.0 1926015 ChemDiv2_000596 COC(=O)C1CC(=O)OC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L03 compound treatment 0.266 0.00835 0.45 0.449 1.0 1316128 ChemDiv2_000597 Cc1cc(C)n(n1)c2nc3n(C)c(=O)[nH]c(=O)c3n2CC(O)COc4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L04 compound treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1647955 ChemDiv2_000598 CCOC(=O)C1CCN(CC1)C(=O)C(CC)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L05 compound treatment 0.235 -0.0226 -1.22 -1.2169 -1.0 1301281 ChemDiv2_000599 CN1CCN(CC1)c2cc3CC(C)(C)CC(=O)c3c4c5ccccc5[nH]c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L06 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1554737 ChemDiv2_000600 COc1ccc(cc1)C2CC(=O)C=C(C2)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L07 compound treatment 0.382 0.124 6.68 6.6826 1.0 1572807 ChemDiv2_000601 CCCc1nn2c(=O)cc(O)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L08 compound treatment 0.361 0.103 5.55 5.5541 1.0 1564811 ChemDiv2_000602 COc1ccc(cc1)C2C(C(=O)c3ccccc3)C(=O)CC(C)(O)C2C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L09 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1983641 ChemDiv2_000603 OC(=O)c1coc(=O)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L10 compound treatment 0.255 -0.00265 -0.14 -0.1421 -1.0 1572099 ChemDiv2_000604 CCCCC(=O)Nc1cc2nn(nc2cc1C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L11 compound treatment 0.32 0.0624 3.35 3.3508 1.0 1230916 ChemDiv2_000605 CC(=O)OCCc1c(C)c([nH]c1COC(=O)C)C(=O)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L12 compound treatment 0.273 0.0154 0.83 0.8251 1.0 1214514 ChemDiv2_000606 COc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L13 compound treatment 0.309 0.0514 2.76 2.7597 1.0 1488751 ChemDiv2_000607 Cc1ccc(N2C(=O)c3ccc(Oc4cccc(N)c4)cc3C2=O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L14 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1226727 ChemDiv2_000608 CC1CCC(C(O1)c2ccc3OCOc3c2)C(=C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L15 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1983642 ChemDiv2_000609 Cc1cc(c2ccccc2)n(n1)c3cc(Cl)ncn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L16 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1983643 ChemDiv2_000610 CC/1=C(C#N)C(=O)N=C(O)\C1=C/c2ccc(o2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L17 compound treatment 0.432 0.174 9.37 9.3695 1.0 1190990 ChemDiv2_000611 O=C1C(CCc2c1sc3nc4CCCCCn4c(=O)c23)Sc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L18 compound treatment 0.289 0.0314 1.68 1.6849 1.0 1983644 ChemDiv2_000612 OCCNC(=O)C1=Cc2ccccc2OC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L19 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1665042 ChemDiv2_000613 CC1(C)CC(CCO1)N(CCCO)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L20 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1377356 ChemDiv2_000614 CC(=O)N1CC2(C)CN(CC(C)(C1)C2O)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L21 compound treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1497960 ChemDiv2_000615 CC1CN(C)C(C)CC1OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L22 compound treatment 0.282 0.0244 1.31 1.3088 1.0 1475210 ChemDiv2_000616 O=C(Oc1cc(=O)oc2ccccc12)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L23 mock treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 L24 mock treatment 0.25 -0.00765 -0.41 -0.4108 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M01 compound treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1205540 ChemDiv2_000617 Cn1c(=N)n(CC(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M02 compound treatment 0.27 0.0124 0.66 0.6639 1.0 1178413 ChemDiv2_000618 Cc1ccc(C)n1c2ccc(SCC(=O)O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M03 compound treatment 0.246 -0.0116 -0.63 -0.6258 -1.0 1983645 ChemDiv2_000619 CCCCC1(O)CCOC(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M04 compound treatment 0.277 0.0194 1.04 1.0401 1.0 1439288 ChemDiv2_000620 COc1cc(CNc2ccc(F)cc2C)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M05 compound treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1983646 ChemDiv2_000621 CC(=O)Nc1[nH]c(O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M06 compound treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1916668 ChemDiv2_000622 Cc1cc(nc2nc(C)nc(C)c12)c3c(C)nc(C)nc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M07 compound treatment 0.317 0.0594 3.19 3.1896 1.0 1918700 ChemDiv2_000623 Nc1cc(n[nH]1)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M08 compound treatment 0.368 0.11 5.93 5.9302 1.0 1983647 ChemDiv2_000624 CN(C)c1nc2SCCn2c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M09 compound treatment 0.295 0.0374 2.01 2.0074 1.0 1340299 ChemDiv2_000625 OC(=O)CCC(=O)Nc1cccc(c1)C(=O)Nc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M10 compound treatment 0.295 0.0374 2.01 2.0074 1.0 1983648 ChemDiv2_000626 COc1n[nH]c2nncnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M11 compound treatment 0.254 -0.00365 -0.2 -0.1959 -1.0 1775101 ChemDiv2_000627 CC(C(=O)O)n1cnc2n(C)c(=O)[nH]c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M12 compound treatment 0.275 0.0174 0.93 0.9326 1.0 1500442 ChemDiv2_000628 Cc1nn(c2ccccc2)c3cc(C)oc(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M13 compound treatment 0.298 0.0404 2.17 2.1686 1.0 1692012 ChemDiv2_000629 COc1cccc(c1)C(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M14 compound treatment 0.265 0.00735 0.4 0.3952 1.0 1712859 ChemDiv2_000630 CNCC(O)c1cccc(OC(=O)c2ccccc2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M15 compound treatment 0.289 0.0314 1.68 1.6849 1.0 1619681 ChemDiv2_000631 Cc1cccc(NC(=O)CC(c2ccccc2)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M16 compound treatment 0.262 0.00435 0.23 0.234 1.0 1983649 ChemDiv2_000632 CC(=O)N1CCC2(CC1)C(=C(N)OC3=C2C(=O)CCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M17 compound treatment 0.273 0.0154 0.83 0.8251 1.0 1683708 ChemDiv2_000633 COc1ccc(OC)c(c1)C(=O)c2coc3ccc(O)c(CN(C)C)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M18 compound treatment 0.271 0.0134 0.72 0.7177 1.0 1009499 ChemDiv2_000634 N(c1ccccn1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M19 compound treatment 0.332 0.0744 4.0 3.9957 1.0 1983650 ChemDiv2_000635 COC(=O)c1cc(no1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M20 compound treatment 0.522 0.264 14.21 14.2059 1.0 1282101 ChemDiv2_000636 CCOC(=O)c1sc(C)c2c(=O)[nH]nnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M21 compound treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1740413 ChemDiv2_000637 CCOC(=O)CN1C(=O)CC(C1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M22 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1710773 ChemDiv2_000638 OCCn1c(=N)n(CCN2CCCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M23 mock treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 M24 mock treatment 0.258 3.55E-4 0.02 0.0191 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N01 compound treatment 0.544 0.286 15.39 15.3881 1.0 1983651 ChemDiv2_000639 CCC1C(=Nc2cc(nn2C1=O)c3ccccc3)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N02 compound treatment 0.416 0.158 8.51 8.5097 1.0 1276122 ChemDiv2_000640 CCOC(=O)CC1=CC(C)(CC(=O)OCC)C(C#N)(C#N)C(=C1C#N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N03 compound treatment 0.335 0.0774 4.16 4.1569 1.0 1240833 ChemDiv2_000641 Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N04 compound treatment 0.263 0.00535 0.29 0.2878 1.0 1442551 ChemDiv2_000642 COc1ccccc1NC(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N05 compound treatment 0.273 0.0154 0.83 0.8251 1.0 1595456 ChemDiv2_000643 CCC(CO)NCC(O)CN1c2ccccc2Sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N06 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1541639 ChemDiv2_000644 COc1cc(cc(OC)c1OC)C(O)c2nccn2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N07 compound treatment 0.249 -0.00865 -0.46 -0.4646 -1.0 1456586 ChemDiv2_000645 O=c1cc(NCc2ccccc2)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N08 compound treatment 0.348 0.0904 4.86 4.8555 1.0 1785996 ChemDiv2_000646 O=c1[nH]c(CN2CCOCC2)nc3c4ccccc4oc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N09 compound treatment 0.51 0.252 13.56 13.561 1.0 1925970 ChemDiv2_000647 Brc1ccc(cc1)c2cccc(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N10 compound treatment 0.527 0.269 14.47 14.4746 1.0 1642709 ChemDiv2_000648 Cc1c(Cl)cccc1c2ccc(o2)C(=O)Nc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N11 compound treatment 0.265 0.00735 0.4 0.3952 1.0 1646729 ChemDiv2_000649 CC1CCN(CC1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N12 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1654426 ChemDiv2_000650 CC1(C)CC(CCO1)C(CC#N)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N13 compound treatment 0.607 0.349 18.77 18.7736 1.0 1362133 ChemDiv2_000651 CC(C)CN1C(=O)c2ccc(cc2C1=O)C(=O)Nc3cccc(OC(=O)C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N14 compound treatment 0.277 0.0194 1.04 1.0401 1.0 1709554 ChemDiv2_000652 CC1CC2(C)Oc3ccccc3C4OCC1(COC(=O)C)C(C)C42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N15 compound treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1430972 ChemDiv2_000653 COC(=O)C1(O)CC(C)N(C)CC1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N16 compound treatment 0.259 0.00135 0.07 0.0728 1.0 1373843 ChemDiv2_000654 C(Cc1ccc2OCOc2c1)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N17 compound treatment 0.279 0.0214 1.15 1.1476 1.0 1983652 ChemDiv2_000655 Brc1cccc(c1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N18 compound treatment 0.372 0.114 6.15 6.1452 1.0 1546870 ChemDiv2_000656 CCC(=O)Nc1nonc1c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N19 compound treatment 0.263 0.00535 0.29 0.2878 1.0 1267286 ChemDiv2_000657 COc1cccc(c1)C(=O)OC2CC(C)N(C)CC2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N20 compound treatment 0.349 0.0914 4.91 4.9092 1.0 1983653 ChemDiv2_000658 Fc1ccc(cc1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N21 compound treatment 0.273 0.0154 0.83 0.8251 1.0 1937652 ChemDiv2_000659 Cc1sc(CO)c(Sc2ccccc2)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N22 compound treatment 0.451 0.193 10.39 10.3905 1.0 1787072 ChemDiv2_000660 O=C(CCc1ccccc1)N2CCC(C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N23 mock treatment 0.258 3.55E-4 0.02 0.0191 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 N24 mock treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O01 compound treatment 0.245 -0.0126 -0.68 -0.6795 -1.0 1565856 ChemDiv2_000661 COC(=O)Cn1c(=N)n(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O02 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1074589 ChemDiv2_000662 Cc1ccc(C)n1c2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O03 compound treatment 0.485 0.227 12.22 12.2176 1.0 1609733 ChemDiv2_000663 CC(=O)Nc1ccc(Cl)c(c1)c2nc3cc(Cl)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O04 compound treatment 0.24 -0.0176 -0.95 -0.9482 -1.0 1307147 ChemDiv2_000664 COCC(C)NCc1c(F)cccc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O05 compound treatment 0.277 0.0194 1.04 1.0401 1.0 1313382 ChemDiv2_000665 COc1cccc(OCC(=O)NCC(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O06 compound treatment 0.267 0.00935 0.5 0.5027 1.0 1268229 ChemDiv2_000666 CN1C(=O)C(C)(C)N(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O07 compound treatment 0.258 3.55E-4 0.02 0.0191 1.0 1726756 ChemDiv2_000667 Oc1cc(nn1CCC#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O08 compound treatment 0.251 -0.00665 -0.36 -0.3571 -1.0 1472736 ChemDiv2_000668 OC(=O)C1CCCCC1C(=O)N(Cc2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O09 compound treatment 0.266 0.00835 0.45 0.449 1.0 1702515 ChemDiv2_000669 O=C1OC2(CCCCC2)C(=C1)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O10 compound treatment 0.256 -0.00165 -0.09 -0.0884 -1.0 1092196 ChemDiv2_000670 Cn1c(NCc2ccccc2)cc(=O)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O11 compound treatment 0.263 0.00535 0.29 0.2878 1.0 1983654 ChemDiv2_000671 COC1(NS(=O)(=O)c2ccc(C)cc2)C(=CC(=O)C=C1C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O12 compound treatment 0.252 -0.00565 -0.3 -0.3034 -1.0 1021573 ChemDiv2_000672 OC(=O)C(O)(C1CCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O13 compound treatment 0.314 0.0564 3.03 3.0284 1.0 1983655 ChemDiv2_000673 NC(=O)c1cccc2/C(=N\O)/c3ccccc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O14 compound treatment 0.261 0.00335 0.18 0.1803 1.0 1663225 ChemDiv2_000674 Cc1ccc2[nH]c(nc2c1)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O15 compound treatment 0.266 0.00835 0.45 0.449 1.0 1363921 ChemDiv2_000675 OCC1N=C(OC1c2ccccc2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O16 compound treatment 0.279 0.0214 1.15 1.1476 1.0 1186574 ChemDiv2_000676 COc1cccc(OC)c1C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O17 compound treatment 0.273 0.0154 0.83 0.8251 1.0 1694007 ChemDiv2_000677 O=S(CCc1ccncc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O18 compound treatment 0.272 0.0144 0.77 0.7714 1.0 1983656 ChemDiv2_000678 OC(C#CCCN1CCCCC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O19 compound treatment 0.3 0.0424 2.28 2.2761 1.0 1983657 ChemDiv2_000679 O=C(Nc1nccs1)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O20 compound treatment 0.419 0.161 8.67 8.6709 1.0 1274649 ChemDiv2_000680 O=C(CCCN1C(=O)c2ccccc2C1=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O21 compound treatment 0.269 0.0114 0.61 0.6102 1.0 1688859 ChemDiv2_000681 OC(=O)Cn1nc2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O22 compound treatment 0.259 0.00135 0.07 0.0728 1.0 1566238 ChemDiv2_000682 CCN(CC)CCn1c(=N)n(CCO)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O23 mock treatment 0.27 0.0124 0.66 0.6639 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 O24 mock treatment 0.259 0.00135 0.07 0.0728 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P01 compound treatment 0.266 0.00835 0.45 0.449 1.0 1458864 ChemDiv2_000683 CCOC(=O)CC1OC(=O)c2cc3C(CC(=O)OCC)OC(=O)c3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P02 compound treatment 0.284 0.0264 1.42 1.4163 1.0 1156981 ChemDiv2_000684 COc1ccc(cc1)C2C(=C(N)OC3=C2CCCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P03 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1548351 ChemDiv2_000685 OC(=O)C1CCC(=O)N1C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P04 compound treatment 0.284 0.0264 1.42 1.4163 1.0 1151267 ChemDiv2_000686 OC(=O)c1cccc(c1)S(=O)(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P05 compound treatment 0.304 0.0464 2.49 2.491 1.0 1925731 ChemDiv2_000687 CCN(CCN)c1ccc2c(=O)[nH][nH]c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P06 compound treatment 0.243 -0.0146 -0.79 -0.787 -1.0 1926080 ChemDiv2_000688 CSC1=NC(C)(C)CC21C=CC(=O)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P07 compound treatment 0.246 -0.0116 -0.63 -0.6258 -1.0 1441445 ChemDiv2_000689 COc1ccccc1Nc2cc(=O)[nH]c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P08 compound treatment 0.254 -0.00365 -0.2 -0.1959 -1.0 1224852 ChemDiv2_000690 COCc1c(nnn1c2nonc2N)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P09 compound treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1259077 ChemDiv2_000691 Nc1cccc2c(ccnc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P10 compound treatment 0.246 -0.0116 -0.63 -0.6258 -1.0 1301756 ChemDiv2_000692 CC(C)(C)NC(=O)Cn1c(=O)n(CC(=O)NC(C)(C)C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P11 compound treatment 0.454 0.196 10.55 10.5517 1.0 1552282 ChemDiv2_000693 CC(Oc1cc(Cl)ccc1Cl)C(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P12 compound treatment 0.27 0.0124 0.66 0.6639 1.0 1539828 ChemDiv2_000694 CCC1(C)CC(CC#N)(CCO1)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P13 compound treatment 0.264 0.00635 0.34 0.3415 1.0 1358124 ChemDiv2_000695 Cn1c(=O)n(C)c2nc(NCc3ccccc3)[nH]c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P14 compound treatment 0.285 0.0274 1.47 1.47 1.0 1562227 ChemDiv2_000696 CC(=O)OCC1(COC(C2C1)c3ccccc3OC(=O)C)CC=C2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P15 compound treatment 0.233 -0.0246 -1.32 -1.3244 -1.0 1574696 ChemDiv2_000697 CC1CC(O)(C(C)CN1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P16 compound treatment 0.26 0.00235 0.13 0.1265 1.0 1210167 ChemDiv2_000698 COc1cccc(CNCc2ccccc2OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P17 compound treatment 0.248 -0.00965 -0.52 -0.5183 -1.0 1983658 ChemDiv2_000699 C/C(=C/CN1CCOCC1)/Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P18 compound treatment 0.457 0.199 10.71 10.7129 1.0 1587286 ChemDiv2_000700 O=C(Cc1ccccc1)Nc2ccc(Cc3ccncc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P19 compound treatment 0.269 0.0114 0.61 0.6102 1.0 1158577 ChemDiv2_000701 CC1CN(C)C(C)CC1OC(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P20 compound treatment 0.296 0.0384 2.06 2.0611 1.0 1983659 ChemDiv2_000702 Oc1ccc(Br)cc1C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P21 compound treatment 0.329 0.0714 3.83 3.8345 1.0 1306783 ChemDiv2_000703 CN(C)Cc1cc(CCNC(=O)c2ccc(Cl)cc2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P22 compound treatment 0.257 -6.45E-4 -0.03 -0.0347 -1.0 1983660 ChemDiv2_000704 O=C(CCc1ccccc1)OCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P23 mock treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1370 P24 mock treatment 0.253 -0.00465 -0.25 -0.2496 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A01 compound treatment 0.438 0.202 10.87 10.8655 1.0 1983661 ChemDiv2_000705 NCCNC(=O)c1ccc(/C=N/O)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A02 compound treatment 0.213 -0.0228 -1.23 -1.2256 -1.0 1983662 ChemDiv2_000706 CN(C)S(=O)(=O)N1CCc2ccccc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A03 compound treatment 0.228 -0.00781 -0.42 -0.4195 -1.0 1077728 ChemDiv2_000707 CC1(C)C2CCC1(C(=O)O)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A04 compound treatment 0.252 0.0162 0.87 0.8702 1.0 1592536 ChemDiv2_000708 CC1(C)C2CCC1(CS(=O)(=O)Nc3ccc(Cl)cc3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A05 compound treatment 0.228 -0.00781 -0.42 -0.4195 -1.0 1359254 ChemDiv2_000709 OC(=O)CCCC(=O)Nc1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A06 compound treatment 0.229 -0.00681 -0.37 -0.3658 -1.0 1190457 ChemDiv2_000710 OCC(NC(=O)c1cncc(Br)c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A07 compound treatment 0.268 0.0322 1.73 1.73 1.0 1983663 ChemDiv2_000711 Cc1ccc(cc1)S(=O)(=O)NCCSc2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A08 compound treatment 0.302 0.0662 3.56 3.5571 1.0 1638925 ChemDiv2_000712 CC(C)CNC(=O)c1cccc(c1)C(=O)NCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A09 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1983664 ChemDiv2_000713 Cc1cc(/C=N/O)c(C)n1c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A10 compound treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1983665 ChemDiv2_000714 OC(CCN1CCCCC1)(CC=C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A11 compound treatment 0.326 0.0902 4.85 4.8468 1.0 1398663 ChemDiv2_000715 Cc1cc(C)n(CC(O)COc2ccccc2C(=O)Nc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A12 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1739156 ChemDiv2_000716 CC(=O)N(Cc1ccco1)Cc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A13 compound treatment 0.488 0.252 13.55 13.5524 1.0 1983666 ChemDiv2_000717 O=C(CSc1nnnn1c2ccccc2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A14 compound treatment 0.464 0.228 12.26 12.2626 1.0 1983667 ChemDiv2_000718 COC(=O)c1ccc(COc2ccc(/C=N\O)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A15 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1297651 ChemDiv2_000719 OC(=O)C1Cc2ccccc2CN1C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A16 compound treatment 0.358 0.122 6.57 6.5664 1.0 1177379 ChemDiv2_000720 CCc1cc(=O)oc2cc(OCC(=O)OC)c(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A17 compound treatment 0.479 0.243 13.07 13.0687 1.0 1522753 ChemDiv2_000721 COc1ccc(cc1)c2oc3ncn(CCCO)c(=N)c3c2c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A18 compound treatment 0.257 0.0212 1.14 1.1389 1.0 1160421 ChemDiv2_000722 N=c1nc(c2ccccc2)c(n[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A19 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1983668 ChemDiv2_000723 CSc1ccc(cc1)c2ncnn2c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A20 compound treatment 0.337 0.101 5.44 5.4379 1.0 1587355 ChemDiv2_000724 CC(=C)C1CC=C(C)C(C1)OC(=O)c2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A21 compound treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1983669 ChemDiv2_000725 COC(=O)c1sc(=S)n(c1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A22 compound treatment 0.237 0.00119 0.06 0.0641 1.0 1983670 ChemDiv2_000726 CC1(C)CC(CC(=O)O)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A23 mock treatment 0.232 -0.00381 -0.2 -0.2046 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 A24 mock treatment 0.256 0.0202 1.09 1.0852 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B01 compound treatment 0.255 0.0192 1.03 1.0314 1.0 1983671 ChemDiv2_000727 N=C1NC(=N)C(Cc2ccccc2)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B02 compound treatment 0.263 0.0272 1.46 1.4613 1.0 1931693 ChemDiv2_000728 Cc1nc(cs1)C2CC(=O)OC32CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B03 compound treatment 0.275 0.0392 2.11 2.1062 1.0 1232766 ChemDiv2_000729 Cc1sc(C(=O)NCCc2ccccc2)c3nc(C)n(CC(=O)NCCc4ccccc4)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B04 compound treatment 0.258 0.0222 1.19 1.1926 1.0 1983672 ChemDiv2_000730 C=CC[C@H]1CC=C[C@@H](N1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B05 compound treatment 0.272 0.0362 1.94 1.945 1.0 1616425 ChemDiv2_000731 Cc1cc(C)c2c(O)n(nc2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B06 compound treatment 0.434 0.198 10.65 10.6505 1.0 1122356 ChemDiv2_000732 Nc1c(C#N)c2nc(C#N)c(C#N)nc2n1CC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B07 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1273370 ChemDiv2_000733 OC1CC(NC2(CCCCC2)C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B08 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1535014 ChemDiv2_000734 COc1ccc(CCNC(=O)C2CCCNC2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B09 compound treatment 0.391 0.155 8.34 8.3398 1.0 1983673 ChemDiv2_000735 CCOC(=O)c1ccc(NC(=O)CNC(=O)C2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B10 compound treatment 0.281 0.0452 2.43 2.4286 1.0 1701072 ChemDiv2_000736 OC(=O)CCCC(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B11 compound treatment 0.285 0.0492 2.64 2.6436 1.0 1565162 ChemDiv2_000737 OC(=O)CCC(=O)Nc1ccc(cc1)C(=O)OC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B12 compound treatment 0.255 0.0192 1.03 1.0314 1.0 1279880 ChemDiv2_000738 CC1CCc2ccccc2N1S(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B13 compound treatment 0.251 0.0152 0.82 0.8165 1.0 1943131 ChemDiv2_000739 NC1=C(C#N)C2=CCSCC2C(c3cccnc3)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B14 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1983674 ChemDiv2_000740 N#CCCN1CCn2c1nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B15 compound treatment 0.334 0.0982 5.28 5.2767 1.0 1271867 ChemDiv2_000741 OCCc1ccc(o1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B16 compound treatment 0.455 0.219 11.78 11.779 1.0 1870756 ChemDiv2_000742 CCOc1ccc(cc1)C2C3=C(NC4=C2C(=O)CCC4)c5ccccc5C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B17 compound treatment 0.429 0.193 10.38 10.3818 1.0 1983675 ChemDiv2_000743 COC(=O)c1ccc(CSc2nnc(c3ccncc3)n2Cc4ccccc4)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B18 compound treatment 0.304 0.0682 3.66 3.6646 1.0 1579582 ChemDiv2_000744 COC(=O)c1c(F)c(F)c(NCCO)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B19 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1313113 ChemDiv2_000745 CCOC(=O)c1ccc(o1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B20 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1983676 ChemDiv2_000746 O=C(CSc1nc(cc(=O)[nH]1)c2ccccc2)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B21 compound treatment 0.249 0.0132 0.71 0.709 1.0 1983677 ChemDiv2_000747 CCOC(=O)C1C(/C=C/c2ccccc2)N=C(O)N=C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B22 compound treatment 0.293 0.0572 3.07 3.0735 1.0 1170079 ChemDiv2_000748 CC(=O)Oc1ccccc1C(=O)OCC(=O)c2ccc(OCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B23 mock treatment 0.266 0.0302 1.62 1.6225 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 B24 mock treatment 0.236 1.94E-4 0.01 0.0104 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C01 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1147534 ChemDiv2_000749 Cc1ccc(NC(=O)C2C(C3c4ccccc4C2c5ccccc35)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C02 compound treatment 0.258 0.0222 1.19 1.1926 1.0 1983678 ChemDiv2_000750 CN(C)S(=O)(=O)n1cnc2cc(C)c(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C03 compound treatment 0.252 0.0162 0.87 0.8702 1.0 1983679 ChemDiv2_000751 c1nc2ncn3c(csc3c2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C04 compound treatment 0.245 0.00919 0.49 0.494 1.0 1588077 ChemDiv2_000752 Nc1ncnc2n(Cc3ccccc3)c4nc5ccccc5nc4c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C05 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1096253 ChemDiv2_000753 COc1cc2CCN(C)C3Cc4cccc(OC)c4-c(c1O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C06 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1983680 ChemDiv2_000754 CC1CN(C(O1)c2ccccc2)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C07 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1267157 ChemDiv2_000755 CCn1c(C)nc2cc(ccc12)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C08 compound treatment 0.285 0.0492 2.64 2.6436 1.0 1983681 ChemDiv2_000756 Cc1ccc(cc1)S(=O)(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C09 compound treatment 0.272 0.0362 1.94 1.945 1.0 1479989 ChemDiv2_000757 COc1ccc(CC(=O)NCc2ccco2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C10 compound treatment 0.245 0.00919 0.49 0.494 1.0 1983682 ChemDiv2_000758 Cc1cccc(c1)C(O)(CCN2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C11 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1983683 ChemDiv2_000759 Cc1nccn1CC(O)COc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C12 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1983684 ChemDiv2_000760 Cc1cc(C)n(CC(O)c2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C13 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1535678 ChemDiv2_000761 CC1CN(Cc2cc(O)c(CN3CC(C)OC(C)C3)cc2O)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C14 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1983685 ChemDiv2_000762 COC(=O)CCc1c(C)nn(c1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C15 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1983686 ChemDiv2_000763 CCOC(=O)C1=C(C)NC(=NC1C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C16 compound treatment 0.331 0.0952 5.12 5.1155 1.0 1536518 ChemDiv2_000764 Clc1cc2c3CCCc3c(=O)oc2cc1OCC(=O)OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C17 compound treatment 0.288 0.0522 2.8 2.8048 1.0 1384387 ChemDiv2_000765 CCCCn1cnc2sc3CCCCc3c2c1=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C18 compound treatment 0.531 0.295 15.86 15.8631 1.0 1983687 ChemDiv2_000766 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cccc3c(=O)[nH][nH]c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C19 compound treatment 0.245 0.00919 0.49 0.494 1.0 1983688 ChemDiv2_000767 Cc1ccsc1c2ncnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C20 compound treatment 0.303 0.0672 3.61 3.6108 1.0 1983689 ChemDiv2_000768 C1C=CC2C1C3CC2C4N=NN(C34)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C21 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1983690 ChemDiv2_000769 CCC1CC(CSC(=N)N)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C22 compound treatment 0.255 0.0192 1.03 1.0314 1.0 1220405 ChemDiv2_000770 CN1C(=O)CCC1(C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C23 mock treatment 0.254 0.0182 0.98 0.9777 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 C24 mock treatment 0.237 0.00119 0.06 0.0641 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D01 compound treatment 0.289 0.0532 2.86 2.8585 1.0 1192052 ChemDiv2_000771 CC(=O)Nc1cccc(c1)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D02 compound treatment 0.274 0.0382 2.05 2.0524 1.0 1658641 ChemDiv2_000772 COc1ccc(cc1)c2csc(Nc3ncccn3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D03 compound treatment 0.283 0.0472 2.54 2.5361 1.0 1678323 ChemDiv2_000773 CCN(CC)CCn1c2ccccc2c3cnc(N)c(C#N)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D04 compound treatment 0.314 0.0782 4.2 4.202 1.0 1983691 ChemDiv2_000774 CC(=O)Nc1cc(Br)c2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D05 compound treatment 0.443 0.207 11.13 11.1341 1.0 1232128 ChemDiv2_000775 COc1cc(Cl)ccc1S(=O)(=O)n2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D06 compound treatment 0.284 0.0482 2.59 2.5898 1.0 1310163 ChemDiv2_000776 COC(=O)c1ccc(C(=O)OC)c(NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D07 compound treatment 0.295 0.0592 3.18 3.1809 1.0 1505119 ChemDiv2_000777 O=C1CC(CC(=C1)NCc2ccc3OCOc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D08 compound treatment 0.257 0.0212 1.14 1.1389 1.0 1220280 ChemDiv2_000778 CC(=O)NC(C(SCc1ccccc1)c2c[nH]c3ccccc23)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D09 compound treatment 0.253 0.0172 0.92 0.9239 1.0 1983692 ChemDiv2_000779 CCN(CC)CCSc1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D10 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1983693 ChemDiv2_000780 CC1=CCC2(C(C1)c3ccccc3)C(=O)OC(C)(C)OC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D11 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1589955 ChemDiv2_000781 CN1C2CCC1CC(C2)OC(=O)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D12 compound treatment 0.389 0.153 8.23 8.2323 1.0 1126189 ChemDiv2_000782 Cc1ccc(nn1)N2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D13 compound treatment 0.408 0.172 9.25 9.2533 1.0 1983694 ChemDiv2_000783 Fc1cccc(c1)C(=O)OCCCc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D14 compound treatment 0.322 0.0862 4.63 4.6319 1.0 1261229 ChemDiv2_000784 CC(C)OCC(O)CNc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D15 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1295257 ChemDiv2_000785 N#Cc1c(Sc2ccccc2)ncc3cc4ccccc4nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D16 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1983695 ChemDiv2_000786 CC1(C)C2CCC1(C)C(C2)OC(=O)CSc3nc(N)cc(=O)[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D17 compound treatment 0.455 0.219 11.78 11.779 1.0 1983696 ChemDiv2_000787 Brc1cccc(c1)c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D18 compound treatment 0.394 0.158 8.5 8.501 1.0 1983697 ChemDiv2_000788 COC(=O)CSc1cccc2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D19 compound treatment 0.568 0.332 17.85 17.8514 1.0 1534969 ChemDiv2_000789 CCCOc1ccc(cc1)S(=O)(=O)n2cc(Br)c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D20 compound treatment 0.317 0.0812 4.36 4.3632 1.0 1983698 ChemDiv2_000790 CCn1c(CSc2nc(C)cc(=O)[nH]2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D21 compound treatment 0.538 0.302 16.24 16.2392 1.0 1983699 ChemDiv2_000791 CCOC(=O)CSc1n[nH]c2nc3sc4COC(C)(C)Cc4c3c(=O)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D22 compound treatment 0.255 0.0192 1.03 1.0314 1.0 1070947 ChemDiv2_000792 COc1ccc(C(=O)CCC(=O)O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D23 mock treatment 0.233 -0.00281 -0.15 -0.1508 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 D24 mock treatment 0.23 -0.00581 -0.31 -0.312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E01 compound treatment 0.266 0.0302 1.62 1.6225 1.0 1210324 ChemDiv2_000793 CCOC(=O)c1[nH]nc(C(=O)c2ccccc2)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E02 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1734930 ChemDiv2_000794 CN(C)S(=O)(=O)NCc1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E03 compound treatment 0.255 0.0192 1.03 1.0314 1.0 1683154 ChemDiv2_000795 COc1ccc(CC(C(=O)O)C(=O)O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E04 compound treatment 0.246 0.0102 0.55 0.5478 1.0 1203029 ChemDiv2_000796 OC(=O)CC(c1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E05 compound treatment 0.252 0.0162 0.87 0.8702 1.0 1939753 ChemDiv2_000797 Cc1nn(c(N2CCCCC2)c1/C=N/O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E06 compound treatment 0.239 0.00319 0.17 0.1716 1.0 1983700 ChemDiv2_000798 Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E07 compound treatment 0.303 0.0672 3.61 3.6108 1.0 1543124 ChemDiv2_000799 CCCn1nnc2c(=O)oc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E08 compound treatment 0.238 0.00219 0.12 0.1179 1.0 1398904 ChemDiv2_000800 CS(=O)(=O)N(Cc1ccccc1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E09 compound treatment 0.264 0.0282 1.52 1.5151 1.0 1282418 ChemDiv2_000801 COc1ccc(cc1)C2CC(=O)C=C(C2)NCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E10 compound treatment 0.243 0.00719 0.39 0.3866 1.0 1983701 ChemDiv2_000802 Cc1ccc(cc1)C(O)(CCN2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E11 compound treatment 0.249 0.0132 0.71 0.709 1.0 1787059 ChemDiv2_000803 C(N1CCCC(C1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E12 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1983702 ChemDiv2_000804 CC(=O)OC(Cn1nc(C)cc1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E13 compound treatment 0.251 0.0152 0.82 0.8165 1.0 809283 ChemDiv2_000805 NC(=O)c1cnn(c1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E14 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1215804 ChemDiv2_000806 Oc1ccc(cc1)C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E15 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1336285 ChemDiv2_000807 COc1cc(ccc1O)C(C#N)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E16 compound treatment 0.464 0.228 12.26 12.2626 1.0 1214922 ChemDiv2_000808 CCc1cc2c3CCCCc3c(=O)oc2cc1OCC(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E17 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1315836 ChemDiv2_000809 N=c1n(Cc2ccccc2)cnc3sc4CCCCc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E18 compound treatment 0.369 0.133 7.16 7.1575 1.0 1983703 ChemDiv2_000810 Fc1c(F)c(F)c(c2nc3C(=O)c4ccccc4C(=O)c3[nH]2)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E19 compound treatment 0.252 0.0162 0.87 0.8702 1.0 1277974 ChemDiv2_000811 CN(C)c1ccc(cc1)c2ncnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E20 compound treatment 0.398 0.162 8.72 8.7159 1.0 1983704 ChemDiv2_000812 Clc1c(sc2ccccc12)c3nnc(SCC(=O)NCCCN4CCOCC4)n3CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E21 compound treatment 0.252 0.0162 0.87 0.8702 1.0 1589695 ChemDiv2_000813 Cc1ccc(CNCc2ccc3OCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E22 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1019828 ChemDiv2_000814 OC(=O)C1CC(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E23 mock treatment 0.25 0.0142 0.76 0.7627 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 E24 mock treatment 0.237 0.00119 0.06 0.0641 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F01 compound treatment 0.25 0.0142 0.76 0.7627 1.0 1983705 ChemDiv2_000815 CCCCn1c(nc2ccccc12)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F02 compound treatment 0.339 0.103 5.55 5.5454 1.0 1134453 ChemDiv2_000816 C(Nc1nc(cs1)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F03 compound treatment 0.254 0.0182 0.98 0.9777 1.0 1713119 ChemDiv2_000817 COc1c(CO)cc(CO)cc(CO)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F04 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1118616 ChemDiv2_000818 CCC(=O)N(Cc1ccc(OC)c(OC)c1)C2CC(C)N(C)CC2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F05 compound treatment 0.332 0.0962 5.17 5.1692 1.0 1331232 ChemDiv2_000819 CC(=O)Nc1cccc(c1)c2nc3cc(Cl)cc(Cl)c3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F06 compound treatment 0.325 0.0892 4.79 4.7931 1.0 1264276 ChemDiv2_000820 COC(=O)c1ccc2[nH]c3CCCCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F07 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1983706 ChemDiv2_000821 CCOC(=O)Cn1cc(Br)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F08 compound treatment 0.29 0.0542 2.91 2.9122 1.0 1662314 ChemDiv2_000822 COC(=O)c1ncn2CC(COc3ccccc3)OC(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F09 compound treatment 0.568 0.332 17.85 17.8514 1.0 1983707 ChemDiv2_000823 C1CCN(C1)c2nncc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F10 compound treatment 0.254 0.0182 0.98 0.9777 1.0 1235523 ChemDiv2_000824 COc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F11 compound treatment 0.253 0.0172 0.92 0.9239 1.0 1788176 ChemDiv2_000825 CCOc1ccc(cc1)C(=O)OC2CCCN(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F12 compound treatment 0.427 0.191 10.27 10.2743 1.0 1275009 ChemDiv2_000826 OC(=O)Cc1cc(=O)oc2c1ccc3ccccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F13 compound treatment 0.238 0.00219 0.12 0.1179 1.0 1447622 ChemDiv2_000827 CCOC(=O)C1(CNC(=O)C2(CNC1=O)C(=O)OCC)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F14 compound treatment 0.24 0.00419 0.23 0.2254 1.0 1070453 ChemDiv2_000828 CC(=O)N1CSCC1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F15 compound treatment 0.326 0.0902 4.85 4.8468 1.0 1156018 ChemDiv2_000829 Cc1ccc(OCCn2c(SCCO)nc3c(N)ncnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F16 compound treatment 0.267 0.0312 1.68 1.6763 1.0 1174651 ChemDiv2_000830 CCOC(=O)C(CC)n1cnc2sc3CCCc3c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F17 compound treatment 0.395 0.159 8.55 8.5547 1.0 1983708 ChemDiv2_000831 Nc1ccc2nc(sc2c1)c3ccccc3Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F18 compound treatment 0.391 0.155 8.34 8.3398 1.0 1983709 ChemDiv2_000832 N/C(=N\O)/CCn1nnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F19 compound treatment 0.411 0.175 9.41 9.4145 1.0 1983710 ChemDiv2_000833 COc1ccc(cc1)C(=O)CCC(=O)Nc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F20 compound treatment 0.349 0.113 6.08 6.0828 1.0 1176071 ChemDiv2_000834 Cc1cc(=O)oc2cc(OCC(=O)NCC3CCCO3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F21 compound treatment 0.241 0.00519 0.28 0.2791 1.0 1983711 ChemDiv2_000835 CC/1C(NC(C\C1=N/O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F22 compound treatment 0.265 0.0292 1.57 1.5688 1.0 1164122 ChemDiv2_000836 CCOC(=CNc1ccc2nsnc2c1)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F23 mock treatment 0.254 0.0182 0.98 0.9777 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 F24 mock treatment 0.225 -0.0108 -0.58 -0.5807 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G01 compound treatment 0.249 0.0132 0.71 0.709 1.0 1621879 ChemDiv2_000837 CC(=O)Nc1ccc(cc1)c2nnc(c3ccccc3)c(n2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G02 compound treatment 0.284 0.0482 2.59 2.5898 1.0 1491285 ChemDiv2_000838 Cc1ccc(cc1S(=O)(=O)N)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G03 compound treatment 0.414 0.178 9.58 9.5757 1.0 1983712 ChemDiv2_000839 COc1cc(/C=C\C(=N\O)\C)ccc1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G04 compound treatment 0.276 0.0402 2.16 2.1599 1.0 1612459 ChemDiv2_000840 NCCC(c1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G05 compound treatment 0.3 0.0642 3.45 3.4496 1.0 1352323 ChemDiv2_000841 Nc1ccc(Oc2cccc3cccnc23)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G06 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1004426 ChemDiv2_000842 COc1ccc(C)c(CN(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G07 compound treatment 0.321 0.0852 4.58 4.5781 1.0 1231663 ChemDiv2_000843 O=c1oc2ccccc2c3n(CCN4CCOCC4)cnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G08 compound treatment 0.38 0.144 7.75 7.7487 1.0 1412885 ChemDiv2_000844 CC1CN(CC(C)O1)S(=O)(=O)c2c(C)cc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G09 compound treatment 0.239 0.00319 0.17 0.1716 1.0 1224421 ChemDiv2_000845 CC1(C)CC(=O)C(C(=O)C1)C2(O)C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G10 compound treatment 0.238 0.00219 0.12 0.1179 1.0 1983713 ChemDiv2_000846 COc1ccccc1C(O)(CCN2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G11 compound treatment 0.25 0.0142 0.76 0.7627 1.0 1924192 ChemDiv2_000847 CC(=O)N1CC(CC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G12 compound treatment 0.246 0.0102 0.55 0.5478 1.0 1291433 ChemDiv2_000848 CC(=O)OC(COc1ccccc1)Cn2nc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G13 compound treatment 0.251 0.0152 0.82 0.8165 1.0 1336923 ChemDiv2_000849 COc1ccc2N(CCN(C)C)c3ccccc3Sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G14 compound treatment 0.525 0.289 15.54 15.5407 1.0 1389604 ChemDiv2_000850 CCCOc1cccc(c1)C(=O)Nc2ccc(Cc3ccncc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G15 compound treatment 0.246 0.0102 0.55 0.5478 1.0 1044584 ChemDiv2_000851 CC(C)Oc1ccc(Cl)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G16 compound treatment 0.262 0.0262 1.41 1.4076 1.0 1678711 ChemDiv2_000852 CCCOc1cccc(CN2CCCCC2c3cccnc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G17 compound treatment 0.254 0.0182 0.98 0.9777 1.0 1186631 ChemDiv2_000853 OCCn1cnc2sc3CCCCc3c2c1=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G18 compound treatment 0.422 0.186 10.01 10.0057 1.0 1983714 ChemDiv2_000854 c1coc(c1)c2nc3cccc4cccc([nH]2)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G19 compound treatment 0.265 0.0292 1.57 1.5688 1.0 1948410 ChemDiv2_000855 COC(=O)c1ccc(cc1)n2ncnc2c3cccc(Br)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G20 compound treatment 0.31 0.0742 3.99 3.987 1.0 1423009 ChemDiv2_000856 Cn1c(=O)n(C)c2[nH]c(=N)c(nc2c1=O)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G21 compound treatment 0.236 1.94E-4 0.01 0.0104 1.0 1983715 ChemDiv2_000857 CC(C)N1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G22 compound treatment 0.245 0.00919 0.49 0.494 1.0 1256411 ChemDiv2_000858 CCNCC1OCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G23 mock treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 G24 mock treatment 0.235 -8.06E-4 -0.04 -0.0433 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H01 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1692288 ChemDiv2_000859 Cc1ccccc1C(=O)NCC2CCCN3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H02 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1259144 ChemDiv2_000860 CC(=O)NC(O)C(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H03 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1983716 ChemDiv2_000861 CC(C)Oc1ccc(CSC(=N)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H04 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1045031 ChemDiv2_000862 CN1C2CCC1CC(C2)OC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H05 compound treatment 0.253 0.0172 0.92 0.9239 1.0 1983717 ChemDiv2_000863 CC(C)Sc1nc(=O)cc(C)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H06 compound treatment 0.485 0.249 13.39 13.3911 1.0 1532798 ChemDiv2_000864 COc1cc(Cl)ccc1S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)cc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H07 compound treatment 0.549 0.313 16.83 16.8304 1.0 1983718 ChemDiv2_000865 O=C(COc1ccccc1)Nc2cccc(c2)c3nnc(o3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H08 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1913198 ChemDiv2_000866 CCOC(=O)/C(=N/O)/C(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H09 compound treatment 0.478 0.242 13.01 13.015 1.0 1137677 ChemDiv2_000867 COc1ccc(cc1)C(=O)c2coc3ccc(OC(=O)C)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H10 compound treatment 0.257 0.0212 1.14 1.1389 1.0 1137038 ChemDiv2_000868 Cc1ccc(OCC(=O)NCCO)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H11 compound treatment 0.236 1.94E-4 0.01 0.0104 1.0 1788180 ChemDiv2_000869 CC(CN1CCOCC1)OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H12 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1569750 ChemDiv2_000870 Cc1cc(C)n(n1)C(=O)C2CCCN2S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H13 compound treatment 0.232 -0.00381 -0.2 -0.2046 -1.0 1983719 ChemDiv2_000871 CCCN1CCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H14 compound treatment 0.253 0.0172 0.92 0.9239 1.0 1316010 ChemDiv2_000872 CCCc1nc(N2CCCC2)c(C#N)c3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H15 compound treatment 0.262 0.0262 1.41 1.4076 1.0 1983720 ChemDiv2_000873 CCCOc1ccc(Cc2nnn(CC(=O)O)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H16 compound treatment 0.285 0.0492 2.64 2.6436 1.0 1983721 ChemDiv2_000874 Clc1nsc(c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H17 compound treatment 0.273 0.0372 2.0 1.9987 1.0 1983722 ChemDiv2_000875 COc1ccc(cc1)C2(CNC(=O)c3ccccc3)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H18 compound treatment 0.245 0.00919 0.49 0.494 1.0 1726157 ChemDiv2_000876 O=C(N1CCCOC1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H19 compound treatment 0.289 0.0532 2.86 2.8585 1.0 1540186 ChemDiv2_000877 CC1C(NC(C(C)C1=NO)c2ccc(C)cc2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H20 compound treatment 0.337 0.101 5.44 5.4379 1.0 1983723 ChemDiv2_000878 CC(Oc1ccc(Cl)cc1)C(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H21 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1935271 ChemDiv2_000879 CC(C)C/1C(NC(C\C1=N/O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H22 compound treatment 0.239 0.00319 0.17 0.1716 1.0 1983724 ChemDiv2_000880 Clc1ccc(cc1)c2csc3ncnc(n4ccnc4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H23 mock treatment 0.24 0.00419 0.23 0.2254 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 H24 mock treatment 0.23 -0.00581 -0.31 -0.312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I01 compound treatment 0.458 0.222 11.94 11.9402 1.0 1735076 ChemDiv2_000881 CCOC(=O)c1ccc(NC2=CC(=O)CC(C2)c3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I02 compound treatment 0.348 0.112 6.03 6.029 1.0 1298201 ChemDiv2_000882 Fc1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I03 compound treatment 0.376 0.14 7.53 7.5337 1.0 1337033 ChemDiv2_000883 CC(=O)Nc1cccc(c2nc3ccccc3s2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I04 compound treatment 0.245 0.00919 0.49 0.494 1.0 1337776 ChemDiv2_000884 CC(=O)Nc1ccc2CCc3ccccc3N(C(=O)C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I05 compound treatment 0.24 0.00419 0.23 0.2254 1.0 1673490 ChemDiv2_000885 Cc1ccnc(NS(=O)(=O)c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I06 compound treatment 0.497 0.261 14.04 14.036 1.0 1983725 ChemDiv2_000886 Cc1cc(SCc2ccccc2)nc(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I07 compound treatment 0.297 0.0612 3.29 3.2884 1.0 1227539 ChemDiv2_000887 CC(C)(C)NC(=O)Cn1nnc(n1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I08 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1277680 ChemDiv2_000888 O=S(=O)(Cc1ccccc1)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I09 compound treatment 0.324 0.0882 4.74 4.7393 1.0 1983726 ChemDiv2_000889 Clc1ccccc1CSc2nccc(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I10 compound treatment 0.233 -0.00281 -0.15 -0.1508 -1.0 1983727 ChemDiv2_000890 O=C1c2ccccc2-c3nc4ncnn4c(c13)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I11 compound treatment 0.245 0.00919 0.49 0.494 1.0 1983728 ChemDiv2_000891 O=C1CC(Cc2ccccc2)(C(=O)N1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I12 compound treatment 0.243 0.00719 0.39 0.3866 1.0 1983729 ChemDiv2_000892 O=C(CN1CCOCC1)OCCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I13 compound treatment 0.355 0.119 6.41 6.4052 1.0 1729145 ChemDiv2_000893 O=c1[nH]cnc2scc(C3COc4ccccc4O3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I14 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1130222 ChemDiv2_000894 NS(=O)(=O)c1ccc2[nH]c3CCCCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I15 compound treatment 0.251 0.0152 0.82 0.8165 1.0 1620585 ChemDiv2_000895 Cc1cc(C)n(n1)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I16 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1172285 ChemDiv2_000896 COc1cc2COC(=O)C3(CCCC3)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I17 compound treatment 0.313 0.0772 4.15 4.1482 1.0 1490754 ChemDiv2_000897 N=c1n(CCCn2ccnc2)cnc3sc4CCCCc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I18 compound treatment 0.579 0.343 18.44 18.4425 1.0 1983730 ChemDiv2_000898 CCCSc1nnc2-c3cccc4cccc(-c2n1)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I19 compound treatment 0.252 0.0162 0.87 0.8702 1.0 1607338 ChemDiv2_000899 C1Oc2ccc(cc2O1)c3ncnn3c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I20 compound treatment 0.373 0.137 7.37 7.3725 1.0 1784154 ChemDiv2_000900 OC(=O)c1c(c2ccccc2)c3oc4ccccc4c3[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I21 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1368237 ChemDiv2_000901 C(C1CC2CC1C=C2)N3CCN(Cc4cccnc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I22 compound treatment 0.418 0.182 9.79 9.7907 1.0 1937481 ChemDiv2_000902 CCOc1ccc(/C=C\C(=N\O)\C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I23 mock treatment 0.238 0.00219 0.12 0.1179 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 I24 mock treatment 0.24 0.00419 0.23 0.2254 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J01 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1305352 ChemDiv2_000903 Cc1ccc2[nH]c3C(CN)CCCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J02 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1602002 ChemDiv2_000904 CC(=O)NC(O)C(=O)c1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J03 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1983731 ChemDiv2_000905 COc1ccc(CSC(=N)N)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J04 compound treatment 0.249 0.0132 0.71 0.709 1.0 1009067 ChemDiv2_000906 OC(=O)c1ccccc1C(=O)Nc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J05 compound treatment 0.32 0.0842 4.52 4.5244 1.0 1691854 ChemDiv2_000907 Cc1cc(=O)nc(SCc2nc3ccccc3n2C)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J06 compound treatment 0.416 0.18 9.68 9.6832 1.0 1361545 ChemDiv2_000908 COc1ccc(cc1)C(=O)OC(COc2ccccc2)Cn3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J07 compound treatment 0.575 0.339 18.23 18.2276 1.0 1673616 ChemDiv2_000909 OC(=O)c1cc(O)ccc1NC(=O)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J08 compound treatment 0.226 -0.00981 -0.53 -0.527 -1.0 1983732 ChemDiv2_000910 CCOC1(O)C(=O)c2ccccc2C(=O)C1(O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J09 compound treatment 0.426 0.19 10.22 10.2206 1.0 1545354 ChemDiv2_000911 Cn1c(CC(=O)c2ccc(O)cc2O)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J10 compound treatment 0.482 0.246 13.23 13.2299 1.0 1534820 ChemDiv2_000912 COc1cccc(OCC(=O)Nc2cccc(C#N)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J11 compound treatment 0.253 0.0172 0.92 0.9239 1.0 1788185 ChemDiv2_000913 CC(CN1CCCCC1)OC(=O)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J12 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1455069 ChemDiv2_000914 Nc1cc(=O)[nH]c(=O)n1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J13 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1983733 ChemDiv2_000915 NC(=O)C1(CCC(=O)N1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J14 compound treatment 0.321 0.0852 4.58 4.5781 1.0 1442783 ChemDiv2_000916 CCCCc1nc2[nH]nc(N)c2c3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J15 compound treatment 0.264 0.0282 1.52 1.5151 1.0 1426702 ChemDiv2_000917 COc1ccc(Cc2nnn(CC(=O)O)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J16 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1983734 ChemDiv2_000918 CC1C2OC(=O)C(C)C2(OC1=O)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J17 compound treatment 0.246 0.0102 0.55 0.5478 1.0 1983735 ChemDiv2_000919 COc1ccc(cc1)C2(CNC(=O)Cc3ccc(OC)c(OC)c3)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J18 compound treatment 0.264 0.0282 1.52 1.5151 1.0 1983736 ChemDiv2_000920 Cc1cc(C)c2c(n[nH]c2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J19 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1518942 ChemDiv2_000921 OC1(CCN(Cc2ccccc2)CC1)C#Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J20 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1983737 ChemDiv2_000922 CCOC(=O)C(Cc1ccccc1)C(=O)Nc2cccc(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J21 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1387807 ChemDiv2_000923 OC(=O)C1Cn2c(S1)nc3-c4ccccc4CC5(CCCC5)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J22 compound treatment 0.245 0.00919 0.49 0.494 1.0 1334352 ChemDiv2_000924 CCN(CC)CCn1nc2-c3ccccc3-c4cccc(c1=O)c42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J23 mock treatment 0.235 -8.06E-4 -0.04 -0.0433 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 J24 mock treatment 0.229 -0.00681 -0.37 -0.3658 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K01 compound treatment 0.362 0.126 6.78 6.7814 1.0 1723526 ChemDiv2_000925 CC(C)C(=O)Nc1ccc2oc(nc2c1)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K02 compound treatment 0.392 0.156 8.39 8.3935 1.0 1446730 ChemDiv2_000926 Cc1ccccc1OCC(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K03 compound treatment 0.493 0.257 13.82 13.821 1.0 1360894 ChemDiv2_000927 CCC(=O)Nc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K04 compound treatment 0.238 0.00219 0.12 0.1179 1.0 1385176 ChemDiv2_000928 OC(=O)C1CCCN(C1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K05 compound treatment 0.272 0.0362 1.94 1.945 1.0 1983738 ChemDiv2_000929 COC(=O)Cn1cnc2scc(c3ccc(OC)c(OC)c3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K06 compound treatment 0.25 0.0142 0.76 0.7627 1.0 1692397 ChemDiv2_000930 OC(=O)CC(C(=O)O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K07 compound treatment 0.49 0.254 13.66 13.6598 1.0 1311081 ChemDiv2_000931 Nc1ccc(Oc2ccc3[nH]c(nc3c2)c4ccc(N)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K08 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1174547 ChemDiv2_000932 CC(=O)Nc1ccc(cc1)C(=O)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K09 compound treatment 0.254 0.0182 0.98 0.9777 1.0 1613872 ChemDiv2_000933 CCN(CC)CC(O)COc1ccccc1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K10 compound treatment 0.336 0.1 5.38 5.3842 1.0 1983739 ChemDiv2_000934 COc1cccc(C2Sc3ccccc3NC4=C2C(=O)c5ccccc45)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K11 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1230827 ChemDiv2_000935 C1Cc2ccccc2C(CN1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K12 compound treatment 0.281 0.0452 2.43 2.4286 1.0 1146439 ChemDiv2_000936 CC(C)(Cc1cc(=O)c2ccccc2[nH]1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K13 compound treatment 0.237 0.00119 0.06 0.0641 1.0 1983740 ChemDiv2_000937 CN(C)CC1Cc2ccccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K14 compound treatment 0.333 0.0972 5.22 5.223 1.0 1950735 ChemDiv2_000938 COc1cc(/C=N/O)ccc1OCc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K15 compound treatment 0.479 0.243 13.07 13.0687 1.0 1787331 ChemDiv2_000939 CC(=O)Nc1ccc(cc1)S(=O)(=O)c2cc(OC(=O)c3ccco3)ccc2OC(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K16 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1983741 ChemDiv2_000940 O=c1[nH]cc(N2CCCCC2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K17 compound treatment 0.39 0.154 8.29 8.286 1.0 1369590 ChemDiv2_000941 CC(C)Cn1cnc2oc(c(c3ccccc3)c2c1=N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K18 compound treatment 0.288 0.0522 2.8 2.8048 1.0 1983742 ChemDiv2_000942 COc1ccc(Cc2nc(C)cc(Cl)n2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K19 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1469650 ChemDiv2_000943 N#Cc1c(sc2CCCCCc12)n3ncnc3c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K20 compound treatment 0.299 0.0632 3.4 3.3959 1.0 1591057 ChemDiv2_000944 CC(C)NC(=O)CCCN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K21 compound treatment 0.265 0.0292 1.57 1.5688 1.0 1727125 ChemDiv2_000945 COc1cc(CNCc2ccc(C)cc2)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K22 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1345263 ChemDiv2_000946 CCN(CC)Cc1cccc2COCc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K23 mock treatment 0.244 0.00819 0.44 0.4403 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 K24 mock treatment 0.241 0.00519 0.28 0.2791 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L01 compound treatment 0.249 0.0132 0.71 0.709 1.0 1433235 ChemDiv2_000947 CCOC(=O)C1CCCc2c1[nH]c3c(cccc23)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L02 compound treatment 0.309 0.0732 3.93 3.9333 1.0 1304087 ChemDiv2_000948 COc1ccccc1OCC(=O)Nc2nc(c(NC(=O)c3ccccc3)s2)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L03 compound treatment 0.257 0.0212 1.14 1.1389 1.0 1983743 ChemDiv2_000949 CCCOc1ccc(CSC(=N)N)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L04 compound treatment 0.301 0.0652 3.5 3.5034 1.0 1357253 ChemDiv2_000950 CC(C)COC(=O)CN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L05 compound treatment 0.313 0.0772 4.15 4.1482 1.0 1393865 ChemDiv2_000951 Clc1ccc(CC2CC(=O)N(Cc3ccccc3)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L06 compound treatment 0.239 0.00319 0.17 0.1716 1.0 1922880 ChemDiv2_000952 CN(C)CCN1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L07 compound treatment 0.264 0.0282 1.52 1.5151 1.0 1228065 ChemDiv2_000953 OC(=O)c1cccc(NC(=O)Cc2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L08 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1509016 ChemDiv2_000954 OCC(O)CNC(=O)C1CCCNC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L09 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1385201 ChemDiv2_000955 CC(=O)Oc1ccc2oc(c(C(=O)N)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L10 compound treatment 0.319 0.0832 4.47 4.4706 1.0 1983744 ChemDiv2_000956 CC1(C)CC(CC(C)(C)N1)NC(=O)CCCOc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L11 compound treatment 0.389 0.153 8.23 8.2323 1.0 1255992 ChemDiv2_000957 CCS(=O)(=O)CCSc1nc2CCCCc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L12 compound treatment 0.246 0.0102 0.55 0.5478 1.0 1583138 ChemDiv2_000958 COC(=O)Cc1cc(=O)oc2cc(O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L13 compound treatment 0.27 0.0342 1.84 1.8375 1.0 1983745 ChemDiv2_000959 Cc1ccc(Oc2ccc(cc2)/C(=N/O)/N)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L14 compound treatment 0.34 0.104 5.6 5.5991 1.0 1926779 ChemDiv2_000960 Cc1cc(=O)oc2ccc(OCC=C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L15 compound treatment 0.236 1.94E-4 0.01 0.0104 1.0 1983746 ChemDiv2_000961 COC(=O)C1C2CC(C)CCC2C(C)(C)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L16 compound treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1788584 ChemDiv2_000962 COC(=O)C(CC(C)C)NC(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L17 compound treatment 0.334 0.0982 5.28 5.2767 1.0 1983747 ChemDiv2_000963 COc1ccc(cc1)C2(CNC(=O)CCOc3ccccc3)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L18 compound treatment 0.373 0.137 7.37 7.3725 1.0 1660804 ChemDiv2_000964 Oc1cccc(c1)N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L19 compound treatment 0.289 0.0532 2.86 2.8585 1.0 1023969 ChemDiv2_000965 c1csc(c1)c2nc3sc(nc3s2)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L20 compound treatment 0.3 0.0642 3.45 3.4496 1.0 1983748 ChemDiv2_000966 CCOC(=O)C(Cc1ccccc1)C(=O)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L21 compound treatment 0.233 -0.00281 -0.15 -0.1508 -1.0 1983749 ChemDiv2_000967 CC(=C)Cc1c(C)nc(N)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L22 compound treatment 0.256 0.0202 1.09 1.0852 1.0 1357437 ChemDiv2_000968 Oc1cccc2cccc(C(=O)N3CCCCC3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L23 mock treatment 0.239 0.00319 0.17 0.1716 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 L24 mock treatment 0.227 -0.00881 -0.47 -0.4732 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M01 compound treatment 0.238 0.00219 0.12 0.1179 1.0 1983750 ChemDiv2_000969 CCCCC1(CC(CSC(=N)N)OC1=O)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M02 compound treatment 0.24 0.00419 0.23 0.2254 1.0 1482189 ChemDiv2_000970 CC1NC(CC=C)Cc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M03 compound treatment 0.302 0.0662 3.56 3.5571 1.0 1173529 ChemDiv2_000971 NC(=O)c1cc(nc2ccccc12)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M04 compound treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1598247 ChemDiv2_000972 Cc1cccc(C)c1NC(=O)C2CCCN(Cc3ccccc3)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M05 compound treatment 0.245 0.00919 0.49 0.494 1.0 1926379 ChemDiv2_000973 Clc1ccc(CSc2nc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M06 compound treatment 0.302 0.0662 3.56 3.5571 1.0 1357181 ChemDiv2_000974 O=C(N(Cc1ccccc1)Cc2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M07 compound treatment 0.542 0.306 16.45 16.4542 1.0 1983751 ChemDiv2_000975 Nc1cccc(c1)c2nnc(o2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M08 compound treatment 0.387 0.151 8.12 8.1248 1.0 1983752 ChemDiv2_000976 COc1ncnc2c3ccccc3[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M09 compound treatment 0.25 0.0142 0.76 0.7627 1.0 1497686 ChemDiv2_000977 OC(COc1cc2ccccc2cc1C(=O)N3CCCCC3)CN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M10 compound treatment 0.241 0.00519 0.28 0.2791 1.0 1684559 ChemDiv2_000978 CCOC(=O)C1=C(C)NC(=O)C(C1c2ccccc2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M11 compound treatment 0.325 0.0892 4.79 4.7931 1.0 1983753 ChemDiv2_000979 CCOC(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M12 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1663648 ChemDiv2_000980 COC(=O)c1ccc(CN2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M13 compound treatment 0.25 0.0142 0.76 0.7627 1.0 1077381 ChemDiv2_000981 Cc1ccc(cc1)S(=O)(=O)N2CCCC2CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M14 compound treatment 0.54 0.304 16.35 16.3467 1.0 1535573 ChemDiv2_000982 Cc1ccc(OCC(=O)N2CCc3ccccc3C2)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M15 compound treatment 0.296 0.0602 3.23 3.2347 1.0 1392409 ChemDiv2_000983 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3sc4CCCCCc4c3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M16 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1780255 ChemDiv2_000984 O=c1[nH]cc(NC2CCCCC2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M17 compound treatment 0.489 0.253 13.61 13.6061 1.0 1118148 ChemDiv2_000985 O=C(CCCN1C(=O)c2ccccc2C1=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M18 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1945381 ChemDiv2_000986 Cc1cc(nc(n1)c2ccccc2)n3cc(Br)c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M19 compound treatment 0.427 0.191 10.27 10.2743 1.0 1983754 ChemDiv2_000987 Cc1c(Cc2cnn(CC=C)c2C)cnn1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M20 compound treatment 0.324 0.0882 4.74 4.7393 1.0 1983755 ChemDiv2_000988 Brc1ccc(CSc2nccc(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M21 compound treatment 0.266 0.0302 1.62 1.6225 1.0 1135203 ChemDiv2_000989 CC1CN(CC(C)O1)C(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M22 compound treatment 0.254 0.0182 0.98 0.9777 1.0 1473621 ChemDiv2_000990 CCOC(=O)c1sc2nc(C)cc(C)c2c1N(C(=O)C)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M23 mock treatment 0.244 0.00819 0.44 0.4403 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 M24 mock treatment 0.228 -0.00781 -0.42 -0.4195 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N01 compound treatment 0.236 1.94E-4 0.01 0.0104 1.0 1211784 ChemDiv2_000991 COc1ccccc1n2cnc(N)c2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N02 compound treatment 0.299 0.0632 3.4 3.3959 1.0 1192899 ChemDiv2_000992 Fc1ccccc1OCC(=O)Nc2nc(c(NC(=O)c3ccccc3)s2)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N03 compound treatment 0.273 0.0372 2.0 1.9987 1.0 1234376 ChemDiv2_000993 COc1ccccc1CC(=O)c2ccc(O)cc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N04 compound treatment 0.239 0.00319 0.17 0.1716 1.0 1030362 ChemDiv2_000994 CCOC(=O)CN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N05 compound treatment 0.278 0.0422 2.27 2.2674 1.0 1983756 ChemDiv2_000995 CCOC(=O)CSc1nn(c2ccccc2)c(=S)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N06 compound treatment 0.269 0.0332 1.78 1.7838 1.0 1132083 ChemDiv2_000996 NC(=O)CCCc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N07 compound treatment 0.353 0.117 6.3 6.2977 1.0 1983757 ChemDiv2_000997 COc1ccc(cc1)C(=O)NCC(=O)NC2=NCCS2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N08 compound treatment 0.244 0.00819 0.44 0.4403 1.0 1232245 ChemDiv2_000998 CC(Cc1c([nH]c2ccccc12)C(=O)O)NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N09 compound treatment 0.304 0.0682 3.66 3.6646 1.0 1306999 ChemDiv2_000999 COc1ccc(CCn2c(N)c(c3nc4ccccc4s3)c5nc(C#N)c(C#N)nc25)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N10 compound treatment 0.358 0.122 6.57 6.5664 1.0 1983758 ChemDiv2_001000 Clc1ccc(cc1)n2nnnc2SC=C=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N11 compound treatment 0.262 0.0262 1.41 1.4076 1.0 1498687 ChemDiv2_001001 OC(CNc1ccc(Cl)cc1)CSc2nc3CCCCc3cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N12 compound treatment 0.237 0.00119 0.06 0.0641 1.0 1592530 ChemDiv2_001002 Cc1ccc(Nc2[nH]c(=O)c3ccccc3c2C(=O)c4ccncc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N13 compound treatment 0.481 0.245 13.18 13.1762 1.0 1872467 ChemDiv2_001003 Cc1ccccc1OCC(=O)Oc2ccc(cc2)c3cnc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N14 compound treatment 0.474 0.238 12.8 12.8 1.0 1983759 ChemDiv2_001004 CCCCc1c(C)c2ccc(OC)c(/C(=N\O)/C)c2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N15 compound treatment 0.238 0.00219 0.12 0.1179 1.0 1224187 ChemDiv2_001005 CC(=O)Nc1c(O)[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N16 compound treatment 0.237 0.00119 0.06 0.0641 1.0 1983760 ChemDiv2_001006 COC(=O)C(CC(C)C)NC(=O)c1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N17 compound treatment 0.237 0.00119 0.06 0.0641 1.0 1983761 ChemDiv2_001007 Clc1ncnc2sc3CC(CCc3c12)(C#N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N18 compound treatment 0.278 0.0422 2.27 2.2674 1.0 1983762 ChemDiv2_001008 Oc1ccc(cc1)N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N19 compound treatment 0.239 0.00319 0.17 0.1716 1.0 1356211 ChemDiv2_001009 CCOC(=O)C1=C(C)NC(=O)c2c(OC)c(OC)ccc2C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N20 compound treatment 0.325 0.0892 4.79 4.7931 1.0 1983763 ChemDiv2_001010 Oc1ccc(cc1O)C(=O)CSc2nc(nc3CCCCc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N21 compound treatment 0.401 0.165 8.88 8.8772 1.0 1265257 ChemDiv2_001011 COc1cccc2cc(c3ccc4OCOc4c3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N22 compound treatment 0.249 0.0132 0.71 0.709 1.0 1983764 ChemDiv2_001012 CCC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N23 mock treatment 0.239 0.00319 0.17 0.1716 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 N24 mock treatment 0.222 -0.0138 -0.74 -0.7419 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O01 compound treatment 0.243 0.00719 0.39 0.3866 1.0 1659045 ChemDiv2_001013 CCC1CC(C)(OC1=O)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O02 compound treatment 0.263 0.0272 1.46 1.4613 1.0 1145383 ChemDiv2_001014 Cc1cccc(NS(=O)(=O)CC2(CCC3CC2=O)C3(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O03 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1670459 ChemDiv2_001015 CC1CC(CC(=O)Nc2ccc(C)cc2)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O04 compound treatment 0.249 0.0132 0.71 0.709 1.0 1625455 ChemDiv2_001016 CCOC(=O)C1CCCN(CCN(C)C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O05 compound treatment 0.277 0.0412 2.21 2.2137 1.0 1629728 ChemDiv2_001017 C=CCN(CC=C)C(=O)c1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O06 compound treatment 0.302 0.0662 3.56 3.5571 1.0 1279517 ChemDiv2_001018 O=C(N1CCc2ccccc2C1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O07 compound treatment 0.524 0.288 15.49 15.4869 1.0 1983765 ChemDiv2_001019 Nc1ccc(cc1)c2nnc(o2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O08 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1170070 ChemDiv2_001020 COc1ccc2n(Cc3ccccc3)c4c(=O)n(C)cnc4c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O09 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1345958 ChemDiv2_001021 OC(COc1ccc(OCC(O)CN2CCCC2)cc1)CN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O10 compound treatment 0.477 0.241 12.96 12.9612 1.0 1983766 ChemDiv2_001022 CCSc1nncc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O11 compound treatment 0.327 0.0912 4.9 4.9006 1.0 1983767 ChemDiv2_001023 COC(=O)c1sc(=Nc2ccccc2)[nH]c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O12 compound treatment 0.245 0.00919 0.49 0.494 1.0 1251479 ChemDiv2_001024 CC(=O)OC1C2CCCC1C(CC2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O13 compound treatment 0.274 0.0382 2.05 2.0524 1.0 1062545 ChemDiv2_001025 C(SC1=NCCS1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O14 compound treatment 0.457 0.221 11.89 11.8865 1.0 1436001 ChemDiv2_001026 Cc1c(Cc2ccccc2)c(=O)oc3c(C)c(OCC(=O)O)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O15 compound treatment 0.278 0.0422 2.27 2.2674 1.0 1129756 ChemDiv2_001027 N=c1n(Cc2ccccc2)cnc3sc4CCCCCc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O16 compound treatment 0.233 -0.00281 -0.15 -0.1508 -1.0 1983768 ChemDiv2_001028 OCCNc1c[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O17 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1983769 ChemDiv2_001029 Cc1c(Cl)cccc1n2ncnc2c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O18 compound treatment 0.253 0.0172 0.92 0.9239 1.0 1380914 ChemDiv2_001030 CN(CCO)C(=O)c1cccc2C(=O)c3ccccc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O19 compound treatment 0.246 0.0102 0.55 0.5478 1.0 1983770 ChemDiv2_001031 CCCn1cc(/C=N/O)c(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O20 compound treatment 0.305 0.0692 3.72 3.7183 1.0 1149542 ChemDiv2_001032 Nc1cc(O)nn1C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O21 compound treatment 0.245 0.00919 0.49 0.494 1.0 1983771 ChemDiv2_001033 CN(C)S(=O)(=O)N(C)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O22 compound treatment 0.26 0.0242 1.3 1.3001 1.0 1485793 ChemDiv2_001034 O=C(Cc1ccccc1)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O23 mock treatment 0.232 -0.00381 -0.2 -0.2046 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 O24 mock treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P01 compound treatment 0.273 0.0372 2.0 1.9987 1.0 1503989 ChemDiv2_001035 Cc1sc2c(=O)n3CCCCCc3nc2c1C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P02 compound treatment 0.245 0.00919 0.49 0.494 1.0 1452782 ChemDiv2_001036 NCc1cnc2CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P03 compound treatment 0.259 0.0232 1.25 1.2464 1.0 1932068 ChemDiv2_001037 COC(=O)C1=C(Nc2ccccc2)SCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P04 compound treatment 0.242 0.00619 0.33 0.3328 1.0 1671338 ChemDiv2_001038 CC(C)CC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P05 compound treatment 0.248 0.0122 0.66 0.6553 1.0 1623692 ChemDiv2_001039 OC(=O)CC(C1CCCO1)C(=O)Nc2ccccc2I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P06 compound treatment 0.223 -0.0128 -0.69 -0.6882 -1.0 1743039 ChemDiv2_001040 CC(Cc1c[nH]c2ccccc12)N3C(=O)CCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P07 compound treatment 0.243 0.00719 0.39 0.3866 1.0 1983772 ChemDiv2_001041 O=C(CNC(=O)c1cccs1)NC2=NCCS2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P08 compound treatment 0.235 -8.06E-4 -0.04 -0.0433 -1.0 1983773 ChemDiv2_001042 O=C1NCCCC(=C1NCCc2ccccc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P09 compound treatment 0.388 0.152 8.18 8.1786 1.0 1983774 ChemDiv2_001043 Cc1cccc(OCCCC(=O)Nc2ccc3OCOc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P10 compound treatment 0.218 -0.0178 -0.96 -0.9569 -1.0 1388315 ChemDiv2_001044 OC(Cc1nc2ccccc2[nH]1)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P11 compound treatment 0.235 -8.06E-4 -0.04 -0.0433 -1.0 1581606 ChemDiv2_001045 OC1CCCCC1Sc2nc3CCCCc3cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P12 compound treatment 0.231 -0.00481 -0.26 -0.2583 -1.0 1488396 ChemDiv2_001046 Clc1ccccc1CSc2nc3CCCC(=O)c3cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P13 compound treatment 0.258 0.0222 1.19 1.1926 1.0 1519481 ChemDiv2_001047 Nc1ccc(cc1)c2ccc(CO)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P14 compound treatment 0.247 0.0112 0.6 0.6015 1.0 1541559 ChemDiv2_001048 COc1ccc(OCC(=O)NCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P15 compound treatment 0.218 -0.0178 -0.96 -0.9569 -1.0 1983775 ChemDiv2_001049 CC(=O)Nc1c(O)n(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P16 compound treatment 0.222 -0.0138 -0.74 -0.7419 -1.0 1983776 ChemDiv2_001050 CC(C)(C)C(=O)Nc1ncccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P17 compound treatment 0.218 -0.0178 -0.96 -0.9569 -1.0 1983777 ChemDiv2_001051 COc1cc(C)c(c(c1)S(=O)(=O)N)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P18 compound treatment 0.232 -0.00381 -0.2 -0.2046 -1.0 1983778 ChemDiv2_001052 COc1ccc(Cc2c(Cl)ncnc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P19 compound treatment 0.286 0.0502 2.7 2.6973 1.0 1983779 ChemDiv2_001053 O=c1ccnc(S/C=C/c2ccccc2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P20 compound treatment 0.206 -0.0298 -1.6 -1.6017 -1.0 1604709 ChemDiv2_001054 OC1CC2CCC1N(Cc3ccccc3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P21 compound treatment 0.224 -0.0118 -0.63 -0.6345 -1.0 1684215 ChemDiv2_001055 NC(=O)C1CC12c3ccccc3-c4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P22 compound treatment 0.227 -0.00881 -0.47 -0.4732 -1.0 1983780 ChemDiv2_001056 CC(C)(C)c1cc(CCC(=O)N2CCNCC2)c(cc1O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P23 mock treatment 0.215 -0.0208 -1.12 -1.1181 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1371 P24 mock treatment 0.226 -0.00981 -0.53 -0.527 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A01 compound treatment 0.236 -0.0135 -0.73 -0.7255 -1.0 1566764 ChemDiv2_001057 COc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A02 compound treatment 0.283 0.0335 1.8 1.8002 1.0 1285036 ChemDiv2_001058 CCCCc1cc(=O)oc2cc(OCC(=O)N(CC)CC)c(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A03 compound treatment 0.228 -0.0215 -1.16 -1.1554 -1.0 1229819 ChemDiv2_001059 CCCN1CCOC(CC(=O)Nc2ccc(Br)cc2Br)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A04 compound treatment 0.299 0.0495 2.66 2.66 1.0 1801186 ChemDiv2_001060 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3ccc(cc3)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A05 compound treatment 0.219 -0.0305 -1.64 -1.639 -1.0 1870883 ChemDiv2_001061 COC(=O)CN1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A06 compound treatment 0.309 0.0595 3.2 3.1974 1.0 1543857 ChemDiv2_001062 CCOc1ccc(cc1)C(=O)N2CCSC2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A07 compound treatment 0.345 0.0955 5.13 5.132 1.0 1178495 ChemDiv2_001063 O=c1oc2cc(OCC#N)ccc2c3CCCc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A08 compound treatment 0.261 0.0115 0.62 0.618 1.0 1983781 ChemDiv2_001064 CCOc1ccc(CCn2cnc3sc4CCCCc4c3c2=N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A09 compound treatment 0.233 -0.0165 -0.89 -0.8867 -1.0 1983782 ChemDiv2_001065 O=C(CCc1ccccc1)NCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A10 compound treatment 0.318 0.0685 3.68 3.681 1.0 1983783 ChemDiv2_001066 COC(=O)CSC1=C(C#N)C(=O)NC2(CCCCC2)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A11 compound treatment 0.247 -0.0025 -0.13 -0.1343 -1.0 1028557 ChemDiv2_001067 O=c1ccn(Cc2ccccc2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A12 compound treatment 0.243 -0.0065 -0.35 -0.3493 -1.0 1983784 ChemDiv2_001068 CC(Cc1ccc2OCOc2c1)/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A13 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1983785 ChemDiv2_001069 CC1(C)CC2(CCCN(CC#N)C2)CCS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A14 compound treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1983786 ChemDiv2_001070 CC1(C)CC2(CCO1)OC(=O)CC2C(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A15 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1938748 ChemDiv2_001071 c1ccc(nc1)c2nnc([nH]2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A16 compound treatment 0.306 0.0565 3.04 3.0362 1.0 1260160 ChemDiv2_001072 CCOc1ccc(cc1)C2CSc3nc4ccccc4n3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A17 compound treatment 0.237 -0.0125 -0.67 -0.6717 -1.0 1983787 ChemDiv2_001073 O=C(OC1CS(=O)(=O)C=C1)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A18 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1066538 ChemDiv2_001074 Cc1ccc(OCCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A19 compound treatment 0.261 0.0115 0.62 0.618 1.0 1305039 ChemDiv2_001075 CCc1ccc(CN(C)CCc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A20 compound treatment 0.335 0.0855 4.59 4.5946 1.0 1983788 ChemDiv2_001076 O=c1[nH]c2ccc(cc2[nH]c1=O)S(=O)(=O)CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A21 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1983789 ChemDiv2_001077 NC(=N)SCC1CN=C(N)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A22 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1667045 ChemDiv2_001078 N#CCCn1c-2c(CCc3ccccc23)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A23 mock treatment 0.259 0.0095 0.51 0.5105 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 A24 mock treatment 0.259 0.0095 0.51 0.5105 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B01 compound treatment 0.458 0.208 11.2 11.2044 1.0 1111456 ChemDiv2_001079 OC1=C(COC1=O)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B02 compound treatment 0.26 0.0105 0.56 0.5642 1.0 1134807 ChemDiv2_001080 CC1(C)CC(O)(CNCc2ccc3OCOc3c2)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B03 compound treatment 0.238 -0.0115 -0.62 -0.618 -1.0 1983790 ChemDiv2_001081 COc1cc(CO)cc(c1OC)c2cc(CO)cc(OC)c2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B04 compound treatment 0.279 0.0295 1.59 1.5853 1.0 1983791 ChemDiv2_001082 CN1CCC(CC1)OC(=O)C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B05 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1983792 ChemDiv2_001083 NC(=O)Cn1c(=N)n(Cc2ccc(Cl)c(Cl)c2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B06 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1417276 ChemDiv2_001084 CC(C)(C)c1nc(CN2CCOCC2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B07 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1983793 ChemDiv2_001085 Clc1ccc(OC(=O)c2ccc3nsnc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B08 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1549223 ChemDiv2_001086 OC(=O)CCCC(=O)Nc1cccc(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B09 compound treatment 0.44 0.191 10.24 10.2371 1.0 1983794 ChemDiv2_001087 CCN(CC)c1cc(Oc2ccccc2)ncn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B10 compound treatment 0.263 0.0135 0.73 0.7255 1.0 1983795 ChemDiv2_001088 CCN(Cc1ccccc1)C2CCN(Cc3ccc(SC)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B11 compound treatment 0.302 0.0525 2.82 2.8212 1.0 1983796 ChemDiv2_001089 Oc1cccc(Cn2c(nc3ccccc23)c4cccc(O)c4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B12 compound treatment 0.238 -0.0115 -0.62 -0.618 -1.0 1983797 ChemDiv2_001090 O=C(NCc1ccco1)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B13 compound treatment 0.282 0.0325 1.75 1.7465 1.0 1983798 ChemDiv2_001091 O=C(COC(=O)CCc1c[nH]c(=O)[nH]1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B14 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1983799 ChemDiv2_001092 O=C(NC1CCCCC1)C2CCN(CC2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B15 compound treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1983800 ChemDiv2_001093 CC(Nc1nc(C)nc2oc(C)nc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B16 compound treatment 0.494 0.245 13.14 13.1389 1.0 1983801 ChemDiv2_001094 CCCOc1ccc(cc1)C(=O)NCC2(CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B17 compound treatment 0.393 0.143 7.71 7.7114 1.0 1983802 ChemDiv2_001095 COc1cc2nc3n(Cc4ccccc4)c5ccccc5n3c(=O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B18 compound treatment 0.37 0.121 6.48 6.4754 1.0 1983803 ChemDiv2_001096 CC(C)Oc1ccc(CN(CCC(c2ccco2)c3ccccc3)C(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B19 compound treatment 0.218 -0.0315 -1.69 -1.6927 -1.0 1983804 ChemDiv2_001097 Oc1c(CNc2ccc(Cl)cc2)cccc1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B20 compound treatment 0.25 5.0E-4 0.03 0.0269 1.0 1983805 ChemDiv2_001098 OC(=O)c1ccc(cc1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B21 compound treatment 0.326 0.0765 4.11 4.111 1.0 1983806 ChemDiv2_001099 COc1cc(CNc2ccc(C)cc2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B22 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1983807 ChemDiv2_001100 Fc1ccc(NC(CC=C)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B23 mock treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 B24 mock treatment 0.255 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C01 compound treatment 0.315 0.0655 3.52 3.5198 1.0 1287147 ChemDiv2_001101 OC(=O)c1ccc(cc1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C02 compound treatment 0.341 0.0915 4.92 4.917 1.0 1669323 ChemDiv2_001102 CCCOC(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C03 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1316103 ChemDiv2_001103 CC1(C)CC(CCO1)c2csc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C04 compound treatment 0.345 0.0955 5.13 5.132 1.0 1945844 ChemDiv2_001104 O=C1N(C(=O)c2ccccc12)c3ccc4[nH]c(=S)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C05 compound treatment 0.285 0.0355 1.91 1.9077 1.0 1983808 ChemDiv2_001105 O=C(Nc1ccccc1)C2=C(CC(CC2=O)c3ccco3)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C06 compound treatment 0.272 0.0225 1.21 1.2091 1.0 1209330 ChemDiv2_001106 COc1ccc(cc1OC)C(=O)N2CCSC2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C07 compound treatment 0.471 0.222 11.9 11.9029 1.0 1344895 ChemDiv2_001107 CCCOC(=O)COc1ccc2c3CCCc3c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C08 compound treatment 0.344 0.0945 5.08 5.0782 1.0 1983809 ChemDiv2_001108 CC1SC(=NC1=O)NC(=O)c2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C09 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1285923 ChemDiv2_001109 CCOC(=O)c1sc2nc3CC(C)(C)OCc3cc2c1NC(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C10 compound treatment 0.25 5.0E-4 0.03 0.0269 1.0 1869099 ChemDiv2_001110 OC(=O)C1Sc2[nH]c(=O)sc2C3C1C(=O)Oc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C11 compound treatment 0.392 0.142 7.66 7.6577 1.0 1714364 ChemDiv2_001111 CC(C)C(=O)Nc1c2CCCc2nc3CCCc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C12 compound treatment 0.25 5.0E-4 0.03 0.0269 1.0 1983810 ChemDiv2_001112 CC(C)C1CC(=O)C=C2CCCCC12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C13 compound treatment 0.333 0.0835 4.49 4.4871 1.0 1983811 ChemDiv2_001113 OC(=O)C1(CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C14 compound treatment 0.298 0.0485 2.61 2.6063 1.0 1983812 ChemDiv2_001114 CC1(C)CC2(CCO1)OC(=O)CC2C(=O)Nc3ccc(Cl)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C15 compound treatment 0.35 0.101 5.4 5.4007 1.0 1983813 ChemDiv2_001115 CSc1nnc-2c(OC=Nc3ccccc32)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C16 compound treatment 0.42 0.171 9.16 9.1623 1.0 1983814 ChemDiv2_001116 OC(CN1C(=O)c2ccccc2C1=O)Cn3nnc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C17 compound treatment 0.269 0.0195 1.05 1.0479 1.0 1200961 ChemDiv2_001117 Cc1cccc(NS(=O)(=O)C2CCS(=O)(=O)C2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C18 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1534779 ChemDiv2_001118 CC(C)Cc1cc([nH]n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C19 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1337046 ChemDiv2_001119 CN(CCc1ccccn1)Cc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C20 compound treatment 0.298 0.0485 2.61 2.6063 1.0 1983815 ChemDiv2_001120 O=C1OC2(CCCC2)OC(=C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C21 compound treatment 0.277 0.0275 1.48 1.4778 1.0 1983816 ChemDiv2_001121 CN1CCC(=CC1)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C22 compound treatment 0.265 0.0155 0.83 0.8329 1.0 1983817 ChemDiv2_001122 N/C(=N\O)/C(c1ccccc1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C23 mock treatment 0.26 0.0105 0.56 0.5642 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 C24 mock treatment 0.263 0.0135 0.73 0.7255 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D01 compound treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1089401 ChemDiv2_001123 CCOC(=O)c1cc(=O)cc(o1)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D02 compound treatment 0.261 0.0115 0.62 0.618 1.0 1983818 ChemDiv2_001124 OC(=O)CC(Cc1ccccc1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D03 compound treatment 0.349 0.0995 5.35 5.3469 1.0 1983819 ChemDiv2_001125 CCN1CCc2nc(SCC(=O)Nc3ccc(OC)cc3)c(C#N)cc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D04 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1488658 ChemDiv2_001126 CC(C)COC(C(=O)O)(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D05 compound treatment 0.239 -0.0105 -0.56 -0.5642 -1.0 1983820 ChemDiv2_001127 OCCn1c(=N)n(CCOc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D06 compound treatment 0.374 0.125 6.69 6.6904 1.0 1983821 ChemDiv2_001128 COc1ccc2[nH]c(nc2c1)c3cccc(N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D07 compound treatment 0.475 0.226 12.12 12.1179 1.0 1777404 ChemDiv2_001129 O=c1c2CCCc2[nH]c3cc(nn13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D08 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1983822 ChemDiv2_001130 OC(=O)CCCC(=O)Nc1ccn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D09 compound treatment 0.244 -0.0055 -0.3 -0.2956 -1.0 1983823 ChemDiv2_001131 O=C1c2ccccc2-c3n[nH]c(=O)c4ccc(N5CCCC5)c1c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D10 compound treatment 0.239 -0.0105 -0.56 -0.5642 -1.0 1983824 ChemDiv2_001132 C1CCC(CC1)N2CCC(CC2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D11 compound treatment 0.387 0.138 7.39 7.389 1.0 1983825 ChemDiv2_001133 O=c1c(C#N)c(nc2SCCn21)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D12 compound treatment 0.479 0.23 12.33 12.3329 1.0 1236638 ChemDiv2_001134 NC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)Nc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D13 compound treatment 0.281 0.0315 1.69 1.6927 1.0 1711380 ChemDiv2_001135 O=C1NC(=O)C(Nc2ccccc2)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D14 compound treatment 0.254 0.0045 0.24 0.2418 1.0 1983826 ChemDiv2_001136 CCOc1ccccc1NC(=O)C2CCN(CC2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D15 compound treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1983827 ChemDiv2_001137 OCC1CC=C(Cl)CC1CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D16 compound treatment 0.239 -0.0105 -0.56 -0.5642 -1.0 1983828 ChemDiv2_001138 OC(=O)CC(Cc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D17 compound treatment 0.346 0.0965 5.19 5.1857 1.0 1983829 ChemDiv2_001139 CCOC(=O)CSc1nc2sc3CSC(C)(C)Cc3c2c(=O)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D18 compound treatment 0.258 0.0085 0.46 0.4568 1.0 1983830 ChemDiv2_001140 CC1(C)CC(CCC(=O)Nc2ccccc2Cl)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D19 compound treatment 0.481 0.232 12.44 12.4403 1.0 1983831 ChemDiv2_001141 COc1ccc(CNc2nccs2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D20 compound treatment 0.296 0.0465 2.5 2.4988 1.0 1346914 ChemDiv2_001142 CC(=O)n1cc(Nc2ccccc2O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D21 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1983832 ChemDiv2_001143 CC(C)n1nc(O)c2C(SCC(=O)Nc21)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D22 compound treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1983833 ChemDiv2_001144 COc1ccc(cc1)N2C(CC=C)c3cccc(C(=O)O)c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D23 mock treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 D24 mock treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E01 compound treatment 0.265 0.0155 0.83 0.8329 1.0 1929317 ChemDiv2_001145 COc1ccccc1c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E02 compound treatment 0.377 0.128 6.85 6.8516 1.0 1983834 ChemDiv2_001146 CCOC(=O)c1ccc2nc3C(=O)c4ccccc4C(=O)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E03 compound treatment 0.236 -0.0135 -0.73 -0.7255 -1.0 1983835 ChemDiv2_001147 CCn1c(=N)n(CCOc2ccc(OC)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E04 compound treatment 0.453 0.203 10.94 10.9357 1.0 1739786 ChemDiv2_001148 O=c1c2cc(sc2nc3c4ccccc4cnn13)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E05 compound treatment 0.236 -0.0135 -0.73 -0.7255 -1.0 1593551 ChemDiv2_001149 COc1cc(cc(OC)c1OC)C2CC(=CC(=O)C2)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E06 compound treatment 0.274 0.0245 1.32 1.3166 1.0 1983836 ChemDiv2_001150 Fc1ccc(cc1)C2OC(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E07 compound treatment 0.459 0.209 11.26 11.2581 1.0 1546701 ChemDiv2_001151 CCCOC(=O)C(C)Oc1ccc2c3CCCc3c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E08 compound treatment 0.236 -0.0135 -0.73 -0.7255 -1.0 1605454 ChemDiv2_001152 COC(=O)COc1ccc(=O)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E09 compound treatment 0.254 0.0045 0.24 0.2418 1.0 1214345 ChemDiv2_001153 CC1(C)Cc2nc(NCCO)c(C#N)cc2CO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E10 compound treatment 0.375 0.126 6.74 6.7441 1.0 1199112 ChemDiv2_001154 CCOc1ccc(cc1)C2Sc3ccccc3NC4=C2C(=O)OC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E11 compound treatment 0.457 0.207 11.15 11.1506 1.0 1983837 ChemDiv2_001155 COC(=O)Cn1cnc2cccc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E12 compound treatment 0.261 0.0115 0.62 0.618 1.0 1983838 ChemDiv2_001156 CC/C(=N\O)/c1ccc(OCC=C)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E13 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1983839 ChemDiv2_001157 Cc1nnc(nn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E14 compound treatment 0.256 0.0065 0.35 0.3493 1.0 1298096 ChemDiv2_001158 OCCN(Cc1ccccc1)S(=O)(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E15 compound treatment 0.24 -0.0095 -0.51 -0.5105 -1.0 1983840 ChemDiv2_001159 COc1ccc2n3CCNC4=NCCc(c43)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E16 compound treatment 0.352 0.102 5.51 5.5081 1.0 1983841 ChemDiv2_001160 Cc1ccc(cc1)S(=O)(=O)NC2C(Sc3ncccn3)c4cccc5cccc2c45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E17 compound treatment 0.279 0.0295 1.59 1.5853 1.0 1983842 ChemDiv2_001161 CN(C)S(=O)(=O)C1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E18 compound treatment 0.554 0.304 16.36 16.3632 1.0 1983843 ChemDiv2_001162 CCOC(=O)c1cc(n[nH]1)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E19 compound treatment 0.27 0.0205 1.1 1.1016 1.0 1550564 ChemDiv2_001163 CN(CCc1ccccn1)Cc2cccc(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E20 compound treatment 0.33 0.0805 4.33 4.3259 1.0 1370129 ChemDiv2_001164 Cc1cc(C)n(n1)C2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E21 compound treatment 0.263 0.0135 0.73 0.7255 1.0 1402497 ChemDiv2_001165 CCOC(=O)C(C)n1cnc2sc3CCCc3c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E22 compound treatment 0.264 0.0145 0.78 0.7792 1.0 1221705 ChemDiv2_001166 COC(=O)c1ccc(OCC(O)CNS(=O)(=O)c2ccccc2C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E23 mock treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 E24 mock treatment 0.253 0.0035 0.19 0.1881 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F01 compound treatment 0.262 0.0125 0.67 0.6717 1.0 1408197 ChemDiv2_001167 CCOC(=O)C1C(CC(O)(CC1=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F02 compound treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1983844 ChemDiv2_001168 CNC(=O)/C(=N\O)/c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F03 compound treatment 0.256 0.0065 0.35 0.3493 1.0 1983845 ChemDiv2_001169 N/C(=N\O)/c1cn(Cc2ccccc2Cl)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F04 compound treatment 0.263 0.0135 0.73 0.7255 1.0 1205180 ChemDiv2_001170 CC1(C)CC(CCO1)N(Cc2ccccc2)C(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F05 compound treatment 0.24 -0.0095 -0.51 -0.5105 -1.0 1983846 ChemDiv2_001171 CC1(C)C/2(C)CCC1(C\C2=N/O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F06 compound treatment 0.428 0.178 9.59 9.5922 1.0 1983847 ChemDiv2_001172 CCCOc1ccc(NC(=O)c2cc(=O)n(C)c(=NC)s2)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F07 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1451381 ChemDiv2_001173 Cc1nn2c(=O)c3CCCc3[nH]c2c1c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F08 compound treatment 0.386 0.137 7.34 7.3352 1.0 1983848 ChemDiv2_001174 Cc1ccc(OCC(=O)N2CCC(CC2)N3CCCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F09 compound treatment 0.272 0.0225 1.21 1.2091 1.0 1983849 ChemDiv2_001175 Oc1ccccc1Oc2ncc(Br)c(n2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F10 compound treatment 0.345 0.0955 5.13 5.132 1.0 1673886 ChemDiv2_001176 O=C1NCC(COc2cccc3ccccc23)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F11 compound treatment 0.275 0.0255 1.37 1.3703 1.0 1983850 ChemDiv2_001177 CCOC(=O)c1nn(c2ccc(Cl)cc2)c(=O)c3c(N)scc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F12 compound treatment 0.389 0.14 7.5 7.4964 1.0 1308543 ChemDiv2_001178 CCc1cccc(C)c1NC(=O)COC(=O)C2CN(C(=O)C2)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F13 compound treatment 0.319 0.0695 3.73 3.7348 1.0 1983851 ChemDiv2_001179 COc1ccc(cc1)C2C3C(Sc4[nH]c(=O)sc24)C(=O)N(C3=O)c5ccc(Br)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F14 compound treatment 0.283 0.0335 1.8 1.8002 1.0 1983852 ChemDiv2_001180 Cc1ccccc1C(=O)N2CCC(CC2)C(=O)Nc3ccc(F)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F15 compound treatment 0.304 0.0545 2.93 2.9287 1.0 1983853 ChemDiv2_001181 Cc1ccccc1OCc2nnc3c4cnn(C)c4ncn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F16 compound treatment 0.243 -0.0065 -0.35 -0.3493 -1.0 1983854 ChemDiv2_001182 NCCC(Cc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F17 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1058740 ChemDiv2_001183 COc1ccc(cc1)n2cnnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F18 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1983855 ChemDiv2_001184 CC1CN(C)C(C)CC1n2nc(O)c3c(C)cc(C)nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F19 compound treatment 0.483 0.234 12.55 12.5478 1.0 1983856 ChemDiv2_001185 Oc1c(CNc2cnc3ccccc3c2)cccc1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F20 compound treatment 0.24 -0.0095 -0.51 -0.5105 -1.0 1527638 ChemDiv2_001186 C=CCC(NCc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F21 compound treatment 0.24 -0.0095 -0.51 -0.5105 -1.0 1983857 ChemDiv2_001187 Oc1nn(C2CCCC2)c3NC(=O)CSC(c13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F22 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1182186 ChemDiv2_001188 C(NC(Cc1ccccc1)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F23 mock treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 F24 mock treatment 0.239 -0.0105 -0.56 -0.5642 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G01 compound treatment 0.312 0.0625 3.36 3.3586 1.0 1632136 ChemDiv2_001189 COc1ccc(cc1)c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G02 compound treatment 0.329 0.0795 4.27 4.2722 1.0 1983858 ChemDiv2_001190 CCN(CC)c1ccc2nc3C(=O)c4ccccc4C(=O)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G03 compound treatment 0.25 5.0E-4 0.03 0.0269 1.0 1983859 ChemDiv2_001191 CN(C)Cc1cc2oc(=O)c3NCCCc3c2cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G04 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1277962 ChemDiv2_001192 O=c1c2ccccc2nc3c4ccccc4c(SCc5ccccc5)nn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G05 compound treatment 0.244 -0.0055 -0.3 -0.2956 -1.0 1983860 ChemDiv2_001193 CC(C)(C)c1ccc(cc1)C2CC(=CC(=O)C2)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G06 compound treatment 0.236 -0.0135 -0.73 -0.7255 -1.0 1187657 ChemDiv2_001194 O=S1(=O)C=C(SCCN2CCCCC2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G07 compound treatment 0.476 0.227 12.17 12.1716 1.0 1734973 ChemDiv2_001195 CC(Oc1ccc2c3CCCc3c(=O)oc2c1)C(=O)OC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G08 compound treatment 0.297 0.0475 2.55 2.5526 1.0 1983861 ChemDiv2_001196 CCc1nc2nonc2c3nc4ccccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G09 compound treatment 0.243 -0.0065 -0.35 -0.3493 -1.0 1983862 ChemDiv2_001197 CCCCN1CC2CC=C(Cl)CC2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G10 compound treatment 0.504 0.255 13.68 13.6763 1.0 1983863 ChemDiv2_001198 N#Cc1c(ncc2cc3ccccc3nc12)N4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G11 compound treatment 0.25 5.0E-4 0.03 0.0269 1.0 1983864 ChemDiv2_001199 CCn1cnc2cccc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G12 compound treatment 0.428 0.178 9.59 9.5922 1.0 1983865 ChemDiv2_001200 O/N=C/1\C(=O)N(CC=C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G13 compound treatment 0.288 0.0385 2.07 2.0689 1.0 1983866 ChemDiv2_001201 COc1ccc(cc1)C(=O)CC(C2C(=O)CCCC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G14 compound treatment 0.282 0.0325 1.75 1.7465 1.0 1270537 ChemDiv2_001202 Clc1ccc(Cn2c(=O)[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G15 compound treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1983867 ChemDiv2_001203 Cc1ccc(cc1S(=O)(=O)NCC2CCCO2)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G16 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1721082 ChemDiv2_001204 Cc1nc2ccc(F)cc2cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G17 compound treatment 0.286 0.0365 1.96 1.9614 1.0 1867192 ChemDiv2_001205 CN(C)CCNC(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G18 compound treatment 0.47 0.221 11.85 11.8492 1.0 1331005 ChemDiv2_001206 CN(CCO)S(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)N(C)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G19 compound treatment 0.321 0.0715 3.84 3.8423 1.0 1983868 ChemDiv2_001207 Clc1ccc(CCNCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G20 compound treatment 0.527 0.278 14.91 14.9123 1.0 1983869 ChemDiv2_001208 COC(=O)c1c(F)c(F)c(Oc2ccc(NC(=O)C)cc2)c(F)c1N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G21 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1867974 ChemDiv2_001209 Cc1c(OC(=O)c2ccccc2)ccc3c4CCCc4c(=O)oc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G22 compound treatment 0.256 0.0065 0.35 0.3493 1.0 1983870 ChemDiv2_001210 O=C(N1CCCCC1)c2ccccc2S(=O)(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G23 mock treatment 0.25 5.0E-4 0.03 0.0269 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 G24 mock treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H01 compound treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1128208 ChemDiv2_001211 COc1ccc(cc1)C(=O)C2=C(O)C(=O)OC32C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H02 compound treatment 0.24 -0.0095 -0.51 -0.5105 -1.0 1983871 ChemDiv2_001212 O/N=C(\C(=O)NC1CCCCC1)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H03 compound treatment 0.358 0.109 5.83 5.8306 1.0 1617502 ChemDiv2_001213 NCc1nc2cc3ccccc3cc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H04 compound treatment 0.263 0.0135 0.73 0.7255 1.0 1575052 ChemDiv2_001214 CCOC(=O)C(C#N)C1(Cc2ccccc2)CCOC(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H05 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1291362 ChemDiv2_001215 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3CC4(C)CC3CC(C)(C)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H06 compound treatment 0.418 0.169 9.05 9.0548 1.0 1983872 ChemDiv2_001216 Clc1ccc(OCCCC(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H07 compound treatment 0.343 0.0935 5.02 5.0245 1.0 1983873 ChemDiv2_001217 NC(=O)c1cc2cc(F)ccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H08 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1983874 ChemDiv2_001218 COc1ccccc1N2CCN(CC2)C3CCN(CC3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H09 compound treatment 0.231 -0.0185 -0.99 -0.9942 -1.0 1983875 ChemDiv2_001219 CC1(C)NC(C)(C)C(=C1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H10 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1040712 ChemDiv2_001220 NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H11 compound treatment 0.243 -0.0065 -0.35 -0.3493 -1.0 1983876 ChemDiv2_001221 CCCCc1nccn1CCn2ccnc2CCCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H12 compound treatment 0.315 0.0655 3.52 3.5198 1.0 1486949 ChemDiv2_001222 CCOC(=O)Cc1c(C)nc2c(C#N)c(C)nn2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H13 compound treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1983877 ChemDiv2_001223 Cc1ccc(OC2CCS(=O)(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H14 compound treatment 0.282 0.0325 1.75 1.7465 1.0 1983878 ChemDiv2_001224 COc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)Nc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H15 compound treatment 0.261 0.0115 0.62 0.618 1.0 1983879 ChemDiv2_001225 Cc1ccc(cc1)c2nnc3c4cnn(Cc5ccccc5)c4ncn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H16 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1517199 ChemDiv2_001226 CC1(C)CC(CCO1)C(CC(=O)N2CCCC2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H17 compound treatment 0.263 0.0135 0.73 0.7255 1.0 1983880 ChemDiv2_001227 OC(=O)c1ccccc1n2cnnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H18 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1983881 ChemDiv2_001228 Cc1cc(N)n(n1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H19 compound treatment 0.26 0.0105 0.56 0.5642 1.0 1983882 ChemDiv2_001229 COc1cccc(NC(=O)c2ccc3C(=O)N(C4CCCCC4)C(=O)c3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H20 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1983883 ChemDiv2_001230 CC(=O)N(C(CC=C)c1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H21 compound treatment 0.235 -0.0145 -0.78 -0.7792 -1.0 1983884 ChemDiv2_001231 OC(C(CN1CCCCC1)CN2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H22 compound treatment 0.254 0.0045 0.24 0.2418 1.0 1983885 ChemDiv2_001232 COC(=O)c1sc(c(C(=O)OC)c1C)S(=O)(=O)NC(C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H23 mock treatment 0.247 -0.0025 -0.13 -0.1343 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 H24 mock treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I01 compound treatment 0.424 0.174 9.38 9.3773 1.0 1983886 ChemDiv2_001233 Cc1ccc(cc1)c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I02 compound treatment 0.349 0.0995 5.35 5.3469 1.0 1983887 ChemDiv2_001234 CS[c+]1cc(oc(c1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I03 compound treatment 0.372 0.123 6.58 6.5829 1.0 1616921 ChemDiv2_001235 O=c1[nH]c(nc2ncn(Cc3ccccc3)c12)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I04 compound treatment 0.232 -0.0175 -0.94 -0.9404 -1.0 1983888 ChemDiv2_001236 COC(=O)C1=C(N)Oc2c(c(=O)oc3ccccc23)C41C(=O)N(C)c5ccccc54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I05 compound treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1983889 ChemDiv2_001237 CN(C)CC#CCC1(O)c2ccccc2-c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I06 compound treatment 0.27 0.0205 1.1 1.1016 1.0 1983890 ChemDiv2_001238 CCOC(=O)N1CCc2c(C(=O)Nc3cc(OC)ccc3OC)c(NC(=O)c4ccco4)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I07 compound treatment 0.244 -0.0055 -0.3 -0.2956 -1.0 1035063 ChemDiv2_001239 Cc1ccc(cc1)c2csc(=N)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I08 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1548344 ChemDiv2_001240 COC(=O)Cn1c(C)nc(=O)c(c1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I09 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1576404 ChemDiv2_001241 CCc1nc(C)cc(N)c1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I10 compound treatment 0.226 -0.0235 -1.26 -1.2628 -1.0 1983891 ChemDiv2_001242 CCOC(=O)c1sc(C)c2c(=O)[nH]c(nc12)c3ccc(SC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I11 compound treatment 0.238 -0.0115 -0.62 -0.618 -1.0 1983892 ChemDiv2_001243 CCOC(=O)C1(CC(=O)c2ccc(F)cc2)C(c3ccccc3)c4ccccc4OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I12 compound treatment 0.295 0.0455 2.45 2.4451 1.0 1983893 ChemDiv2_001244 COc1ccc(NC(=O)CC(c2ccco2)c3ccccc3OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I13 compound treatment 0.451 0.202 10.83 10.8282 1.0 1983894 ChemDiv2_001245 CCOC(=O)c1cn2nc(sc3c(F)c(F)c(F)c(c1=O)c32)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I14 compound treatment 0.274 0.0245 1.32 1.3166 1.0 1645696 ChemDiv2_001246 OC(=O)c1ccc(CN2C(=O)CSC2=S)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I15 compound treatment 0.238 -0.0115 -0.62 -0.618 -1.0 1983895 ChemDiv2_001247 COC(=O)OC1CS(=O)(=O)C=C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I16 compound treatment 0.326 0.0765 4.11 4.111 1.0 1871711 ChemDiv2_001248 OCCSc1c(c2ccccc2)c3cc(Cl)ccc3[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I17 compound treatment 0.273 0.0235 1.26 1.2628 1.0 1867193 ChemDiv2_001249 CN(C)CCOC(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I18 compound treatment 0.287 0.0375 2.02 2.0152 1.0 1182511 ChemDiv2_001250 ON=C1c2cc(ccc2-c3ccc(cc13)S(=O)(=O)N4CCCC4)S(=O)(=O)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I19 compound treatment 0.476 0.227 12.17 12.1716 1.0 1983896 ChemDiv2_001251 Cc1cc(Br)ccc1NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I20 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1656441 ChemDiv2_001252 Nc1nc(O)c(CC(=O)O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I21 compound treatment 0.24 -0.0095 -0.51 -0.5105 -1.0 1867737 ChemDiv2_001253 COc1cc(COc2ccc3c(C)c(CC(=O)O)c(=O)oc3c2C)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I22 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1461197 ChemDiv2_001254 OC(=O)CSCC(=O)N1CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I23 mock treatment 0.261 0.0115 0.62 0.618 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 I24 mock treatment 0.257 0.0075 0.4 0.403 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J01 compound treatment 0.27 0.0205 1.1 1.1016 1.0 1661930 ChemDiv2_001255 OC1=C(C(=O)c2ccc(Br)cc2)C3(OC1=O)C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J02 compound treatment 0.332 0.0825 4.43 4.4334 1.0 1983897 ChemDiv2_001256 O/N=C(\C(=O)NCCc1ccccc1)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J03 compound treatment 0.256 0.0065 0.35 0.3493 1.0 1983898 ChemDiv2_001257 NC(=O)Cn1c(CCCCc2nc3ccccc3n2CC(=O)N)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J04 compound treatment 0.287 0.0375 2.02 2.0152 1.0 1983899 ChemDiv2_001258 CCOC(=O)c1oc2CCCC(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J05 compound treatment 0.381 0.132 7.07 7.0665 1.0 1983900 ChemDiv2_001259 O/N=C/c1ccc2cccc(OCc3ccccc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J06 compound treatment 0.382 0.133 7.12 7.1203 1.0 1983901 ChemDiv2_001260 Cc1ccc(OCCCC(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J07 compound treatment 0.317 0.0675 3.63 3.6273 1.0 1983902 ChemDiv2_001261 NC(=O)c1ccc(cc1)n2nnnc2SCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J08 compound treatment 0.244 -0.0055 -0.3 -0.2956 -1.0 1983903 ChemDiv2_001262 COc1ccc(Br)cc1CN2CCC(CC2)N3CCN(CCO)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J09 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1983904 ChemDiv2_001263 Oc1ccc2ccccc2c1CC3CCCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J10 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1473099 ChemDiv2_001264 OC(=O)c1cccc(c1)C(=O)c2cccc(c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J11 compound treatment 0.432 0.183 9.81 9.8072 1.0 1983905 ChemDiv2_001265 O(c1ccc2[nH]cnc2c1)c3ccc4nc[nH]c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J12 compound treatment 0.341 0.0915 4.92 4.917 1.0 1190212 ChemDiv2_001266 Cc1cc(=O)n2ncc(c3ccccc3)c2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J13 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1347362 ChemDiv2_001267 COc1cc2CCN(Cc2cc1OC)C(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J14 compound treatment 0.244 -0.0055 -0.3 -0.2956 -1.0 1983906 ChemDiv2_001268 COC(=O)c1cc(=O)nc2sccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J15 compound treatment 0.344 0.0945 5.08 5.0782 1.0 1983907 ChemDiv2_001269 CC(C)c1ccc(C)cc1OCc2nnc3c4cnn(Cc5ccccc5)c4ncn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J16 compound treatment 0.314 0.0645 3.47 3.4661 1.0 1187556 ChemDiv2_001270 Cc1ccccc1NC(=O)CC(Cc2ccccc2)C3CCOC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J17 compound treatment 0.51 0.261 14.0 13.9987 1.0 1983908 ChemDiv2_001271 C=CCSc1nnc-2c(OC=Nc3ccccc32)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J18 compound treatment 0.247 -0.0025 -0.13 -0.1343 -1.0 1983909 ChemDiv2_001272 Cc1nn(C2CCCCC2)c3nc(C)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J19 compound treatment 0.61 0.36 19.37 19.3725 1.0 1983910 ChemDiv2_001273 COc1cc(ccc1OC(=O)C)C(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J20 compound treatment 0.264 0.0145 0.78 0.7792 1.0 1232640 ChemDiv2_001274 CC1CC2N(Cc3ccccc13)C(=O)c4c2cccc4C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J21 compound treatment 0.247 -0.0025 -0.13 -0.1343 -1.0 1277719 ChemDiv2_001275 OC1CCCCC1N2CCC(C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J22 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1983911 ChemDiv2_001276 COC(=O)Nc1ccccc1C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J23 mock treatment 0.237 -0.0125 -0.67 -0.6717 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 J24 mock treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K01 compound treatment 0.403 0.154 8.25 8.2488 1.0 1983912 ChemDiv2_001277 S=c1[nH]nc(Cc2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K02 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1983913 ChemDiv2_001278 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K03 compound treatment 0.27 0.0205 1.1 1.1016 1.0 1983914 ChemDiv2_001279 CNc1nc2ncn(Cc3ccccc3)c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K04 compound treatment 0.492 0.242 13.03 13.0314 1.0 1351768 ChemDiv2_001280 COc1ccc2cnn(c3nc4ccccc4s3)c(=O)c2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K05 compound treatment 0.441 0.192 10.29 10.2908 1.0 1145885 ChemDiv2_001281 OC(=O)c1cccc(c1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K06 compound treatment 0.274 0.0245 1.32 1.3166 1.0 1983915 ChemDiv2_001282 CSc1nc(C)c2cc(C)oc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K07 compound treatment 0.268 0.0185 0.99 0.9942 1.0 1983916 ChemDiv2_001283 O=C1C2=C(NC(=O)SC2c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K08 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1983917 ChemDiv2_001284 Cc1nc(n(n1)c2ccccc2)C(C)(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K09 compound treatment 0.289 0.0395 2.12 2.1226 1.0 1723894 ChemDiv2_001285 Cc1ccc(Cc2cnc(CN3CCCCC3)c(O)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K10 compound treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1983918 ChemDiv2_001286 CCC(CO)n1cnnc1c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K11 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1983919 ChemDiv2_001287 COC(=O)C1=C(O)CCN(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K12 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1983920 ChemDiv2_001288 COc1ccc(NC(=O)CC(c2ccco2)c3ccc(F)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K13 compound treatment 0.303 0.0535 2.87 2.875 1.0 1528670 ChemDiv2_001289 CCOc1cccc(=O)c2c(C)[nH]c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K14 compound treatment 0.281 0.0315 1.69 1.6927 1.0 1180259 ChemDiv2_001290 COc1ccc(cc1OC)C(Nc2cc(C)on2)c3c(C)[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K15 compound treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1983921 ChemDiv2_001291 COC(=O)OC1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K16 compound treatment 0.276 0.0265 1.42 1.4241 1.0 1983922 ChemDiv2_001292 CC1C(Cc2ccc(C)cc2)C(=O)N(C1=O)c3ccc(cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K17 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1659475 ChemDiv2_001293 CN(CCc1ccccn1)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K18 compound treatment 0.444 0.195 10.45 10.452 1.0 1718405 ChemDiv2_001294 NC(=O)c1cc(nc2ccccc12)c3ccc(COc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K19 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1983923 ChemDiv2_001295 Clc1cc(oc(=O)c1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K20 compound treatment 0.306 0.0565 3.04 3.0362 1.0 1983924 ChemDiv2_001296 C/C(=N\O)/c1cn(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K21 compound treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1252974 ChemDiv2_001297 COC(=O)c1ccc(COc2ccc3ccc(=O)oc3c2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K22 compound treatment 0.261 0.0115 0.62 0.618 1.0 1503924 ChemDiv2_001298 OC(=O)CCCC(=O)N1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K23 mock treatment 0.262 0.0125 0.67 0.6717 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 K24 mock treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L01 compound treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1785504 ChemDiv2_001299 CC(=O)N1C(Cc2ccccc2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L02 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1983925 ChemDiv2_001300 O/N=C(\C(=O)NCCN1CCCCC1)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L03 compound treatment 0.518 0.269 14.43 14.4286 1.0 1242120 ChemDiv2_001301 O=C(Nc1ccc2nsnc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L04 compound treatment 0.294 0.0445 2.39 2.3913 1.0 1445441 ChemDiv2_001302 CCN(CC)Cc1cc(CCNC(=O)c2ccc(Cl)cc2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L05 compound treatment 0.405 0.156 8.36 8.3562 1.0 1118842 ChemDiv2_001303 OC(=O)c1ccc2C(=O)OC(c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L06 compound treatment 0.33 0.0805 4.33 4.3259 1.0 1246752 ChemDiv2_001304 Brc1ccc2ncn(CC(=O)OCc3ccccc3)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L07 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1983926 ChemDiv2_001305 OC(C(CC(=O)O)C(=O)O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L08 compound treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1983927 ChemDiv2_001306 COc1ccc(CN2CCC(CC2)N3CCN(CCO)CC3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L09 compound treatment 0.291 0.0415 2.23 2.2301 1.0 1983928 ChemDiv2_001307 CC(C)COC(=O)CCc1c(C)nc(N)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L10 compound treatment 0.287 0.0375 2.02 2.0152 1.0 1983929 ChemDiv2_001308 OC(CNC(=O)c1ccccc1C(=O)O)COc2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L11 compound treatment 0.26 0.0105 0.56 0.5642 1.0 1983930 ChemDiv2_001309 CSCn1c(C)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L12 compound treatment 0.371 0.122 6.53 6.5292 1.0 1983931 ChemDiv2_001310 Cc1nn2c(=O)c(Cc3ccccc3)c(C)[nH]c2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L13 compound treatment 0.313 0.0635 3.41 3.4124 1.0 1158203 ChemDiv2_001311 Cc1nn2c(SCC2(O)c3ccccc3)nc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L14 compound treatment 0.228 -0.0215 -1.16 -1.1554 -1.0 1983932 ChemDiv2_001312 CC1(C)COC(=N1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L15 compound treatment 0.294 0.0445 2.39 2.3913 1.0 1983933 ChemDiv2_001313 Clc1ccc(OCc2nnc3c4cnn(c5ccccc5)c4ncn23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L16 compound treatment 0.283 0.0335 1.8 1.8002 1.0 1983934 ChemDiv2_001314 CCOC(=O)C(C#N)C(Cc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L17 compound treatment 0.406 0.157 8.41 8.41 1.0 1983935 ChemDiv2_001315 CC(C)CSc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L18 compound treatment 0.433 0.184 9.86 9.8609 1.0 1360391 ChemDiv2_001316 OC(=O)c1cccc(c1)S(=O)(=O)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L19 compound treatment 0.239 -0.0105 -0.56 -0.5642 -1.0 1983936 ChemDiv2_001317 CC(C)(C)c1cc(Cl)c(O)c(NC(=O)c2cncc(Br)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L20 compound treatment 0.233 -0.0165 -0.89 -0.8867 -1.0 1518347 ChemDiv2_001318 CC(CC=C)(NCc1ccccc1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L21 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1983937 ChemDiv2_001319 CCOc1cc(cc(OCC)c1OCC)C(=O)Oc2cc(=O)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L22 compound treatment 0.482 0.233 12.49 12.4941 1.0 1983938 ChemDiv2_001320 CCc1cccc2/C(=N/O)/C(=O)Nc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L23 mock treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 L24 mock treatment 0.245 -0.0045 -0.24 -0.2418 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M01 compound treatment 0.267 0.0175 0.94 0.9404 1.0 1396886 ChemDiv2_001321 Cc1ccc(c2ccccc2)n1c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M02 compound treatment 0.243 -0.0065 -0.35 -0.3493 -1.0 1983939 ChemDiv2_001322 C[c+]1cc(oc(c1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M03 compound treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1983940 ChemDiv2_001323 O/N=C/c1cn(CC(=O)N2CCOCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M04 compound treatment 0.243 -0.0065 -0.35 -0.3493 -1.0 1141517 ChemDiv2_001324 CC(C)(O)C1CCC2(C)CC1CC(=O)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M05 compound treatment 0.274 0.0245 1.32 1.3166 1.0 1467457 ChemDiv2_001325 COc1ccc(CCNc2nc(C)cc(=O)[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M06 compound treatment 0.325 0.0755 4.06 4.0572 1.0 1417278 ChemDiv2_001326 O=C(COc1ccc2oc3CCCCc3c2c1)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M07 compound treatment 0.333 0.0835 4.49 4.4871 1.0 1983941 ChemDiv2_001327 Cc1cc(=O)nc(Nc2nc3ccccc3s2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M08 compound treatment 0.269 0.0195 1.05 1.0479 1.0 1983942 ChemDiv2_001328 CC1(C)CC(=O)c2c(onc2C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M09 compound treatment 0.261 0.0115 0.62 0.618 1.0 1277810 ChemDiv2_001329 COc1ccccc1C2(CCNC(=O)c3ccccc3C(=O)O)CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M10 compound treatment 0.265 0.0155 0.83 0.8329 1.0 1730648 ChemDiv2_001330 Cc1ccc2n3CCN(CCC#N)c4cccc(c2c1)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M11 compound treatment 0.321 0.0715 3.84 3.8423 1.0 1983943 ChemDiv2_001331 Cc1c(CO)cnn1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M12 compound treatment 0.369 0.12 6.42 6.4217 1.0 1983944 ChemDiv2_001332 CC(=O)N(CCC(Cc1ccccc1)c2ccco2)C(=O)Cc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M13 compound treatment 0.256 0.0065 0.35 0.3493 1.0 1983945 ChemDiv2_001333 Cc1nc2nc(C)n(c3ccccc3)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M14 compound treatment 0.279 0.0295 1.59 1.5853 1.0 1488058 ChemDiv2_001334 Cc1[nH]c2ccccc2c1C(Nc3cc(C)ccn3)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M15 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1020700 ChemDiv2_001335 O=S1(=O)CCC(C1)OC2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M16 compound treatment 0.258 0.0085 0.46 0.4568 1.0 1786227 ChemDiv2_001336 CCC(C)n1c(=O)[nH]c2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M17 compound treatment 0.267 0.0175 0.94 0.9404 1.0 1545547 ChemDiv2_001337 CCOc1ccccc1CN(C)CCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M18 compound treatment 0.272 0.0225 1.21 1.2091 1.0 1983946 ChemDiv2_001338 Cc1ccc(NC(=O)C/C(=N/O)/N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M19 compound treatment 0.262 0.0125 0.67 0.6717 1.0 1983947 ChemDiv2_001339 CC(C)N(C(C)C)C(=O)C1CC(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M20 compound treatment 0.274 0.0245 1.32 1.3166 1.0 1699619 ChemDiv2_001340 Cc1[nH]c2ccc(CN)cc2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M21 compound treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1418014 ChemDiv2_001341 COC(=O)c1cc(COc2ccc3ccc(=O)oc3c2)c(C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M22 compound treatment 0.257 0.0075 0.4 0.403 1.0 1588606 ChemDiv2_001342 CN(C)c1ncn(Cc2c(Cl)cccc2Cl)c3ncnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M23 mock treatment 0.256 0.0065 0.35 0.3493 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 M24 mock treatment 0.253 0.0035 0.19 0.1881 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N01 compound treatment 0.249 -5.0E-4 -0.03 -0.0269 -1.0 1983948 ChemDiv2_001343 CN(C)c1cc(C)nc(N2CCCCC2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N02 compound treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1983949 ChemDiv2_001344 O=C(NCCCn1ccnc1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N03 compound treatment 0.251 0.0015 0.08 0.0806 1.0 1983950 ChemDiv2_001345 CCCCn1c(=N)n(CC(=O)N)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N04 compound treatment 0.265 0.0155 0.83 0.8329 1.0 1359801 ChemDiv2_001346 COC(=O)N(C)CCCC1(C)C(=O)N(C)c2ccc(O)cc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N05 compound treatment 0.267 0.0175 0.94 0.9404 1.0 1983951 ChemDiv2_001347 O=c1nc(nc([nH]1)N2CCCCCC2)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N06 compound treatment 0.308 0.0585 3.14 3.1437 1.0 1983952 ChemDiv2_001348 COc1ccc(cc1)C(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N07 compound treatment 0.395 0.145 7.82 7.8189 1.0 1867761 ChemDiv2_001349 COC(=O)Cc1c(C)c2ccc(O)cc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N08 compound treatment 0.25 5.0E-4 0.03 0.0269 1.0 1983953 ChemDiv2_001350 CCn1c2ccccc2c3cc(CN4CCC(CC4)N5CCN(CCO)CC5)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N09 compound treatment 0.299 0.0495 2.66 2.66 1.0 1983954 ChemDiv2_001351 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N10 compound treatment 0.237 -0.0125 -0.67 -0.6717 -1.0 1983955 ChemDiv2_001352 CCOc1ccc(NC(=O)CC2CC(C)(C)OC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N11 compound treatment 0.319 0.0695 3.73 3.7348 1.0 1983956 ChemDiv2_001353 CC(=O)Nc1ccccc1C(=O)OCC(=O)Nc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N12 compound treatment 0.267 0.0175 0.94 0.9404 1.0 1983957 ChemDiv2_001354 COCc1cc(=O)n2ncc(c3ccc(Cl)cc3)c2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N13 compound treatment 0.301 0.0515 2.77 2.7675 1.0 1284482 ChemDiv2_001355 CC(C)CNc1nnnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N14 compound treatment 0.252 0.0025 0.13 0.1343 1.0 1983958 ChemDiv2_001356 COc1cccc(NC(=O)C2CC(=O)n3cnnc3S2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N15 compound treatment 0.428 0.178 9.59 9.5922 1.0 1983959 ChemDiv2_001357 Cc1cccc(C)c1OCc2nnc3c4cnn(c5ccccc5)c4ncn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N16 compound treatment 0.265 0.0155 0.83 0.8329 1.0 1216051 ChemDiv2_001358 CCOC(=O)C(C#N)C(c1ccco1)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N17 compound treatment 0.257 0.0075 0.4 0.403 1.0 1006245 ChemDiv2_001359 Oc1ccc(CNC2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N18 compound treatment 0.289 0.0395 2.12 2.1226 1.0 1983960 ChemDiv2_001360 COC(=O)NC1c2ccccc2Oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N19 compound treatment 0.341 0.0915 4.92 4.917 1.0 1983961 ChemDiv2_001361 Cc1ccc(OC(=O)C(CCS(=O)(=O)C)N2C(=O)c3ccccc3C2=O)c(c1)n4nc5ccccc5n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N20 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1983962 ChemDiv2_001362 Cc1cccc(NC(CC=C)c2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N21 compound treatment 0.234 -0.0155 -0.83 -0.8329 -1.0 1983963 ChemDiv2_001363 CC(CC(=O)O)CC(=O)Nc1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N22 compound treatment 0.282 0.0325 1.75 1.7465 1.0 1983964 ChemDiv2_001364 CN(C)c1nc(Nc2ccc(F)cc2)nc(n1)n3cccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N23 mock treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 N24 mock treatment 0.236 -0.0135 -0.73 -0.7255 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O01 compound treatment 0.237 -0.0125 -0.67 -0.6717 -1.0 1983965 ChemDiv2_001365 CC(C)C1C(=C(N)SC(=C1C#N)N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O02 compound treatment 0.28 0.0305 1.64 1.639 1.0 1983966 ChemDiv2_001366 COc1ccccc1NC(=O)CSC2=NC(=O)CC(N2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O03 compound treatment 0.254 0.0045 0.24 0.2418 1.0 1870793 ChemDiv2_001367 COC(=O)c1cc(OC)c(OC)cc1n2cnc3cc(OC)c(OC)cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O04 compound treatment 0.279 0.0295 1.59 1.5853 1.0 1983967 ChemDiv2_001368 Cc1nn2c(csc2nc1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O05 compound treatment 0.271 0.0215 1.16 1.1554 1.0 1983968 ChemDiv2_001369 COc1ccc(cc1)c2csc3ncnc(Cl)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O06 compound treatment 0.281 0.0315 1.69 1.6927 1.0 1129614 ChemDiv2_001370 Cc1cc(no1)N2C(=O)CC(Cc3ccc(C)cc3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O07 compound treatment 0.394 0.144 7.77 7.7651 1.0 1396500 ChemDiv2_001371 CC(O)c1oc2ccc3c(C)cc(=O)oc3c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O08 compound treatment 0.431 0.181 9.75 9.7534 1.0 1983969 ChemDiv2_001372 COc1ccc(cc1)C2NC3=C(CCC3)C4(C#N)C(OC)(OC)N=C(N)C24C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O09 compound treatment 0.247 -0.0025 -0.13 -0.1343 -1.0 1925590 ChemDiv2_001373 CC(C)Cn1ccc(=O)n(CC(C)C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O10 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1983970 ChemDiv2_001374 COC(=O)COc1nc(C)nc2c1sc3nc(C)cc(C)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O11 compound treatment 0.258 0.0085 0.46 0.4568 1.0 1983971 ChemDiv2_001375 CCC1(C)CC(CCO1)C(=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O12 compound treatment 0.386 0.137 7.34 7.3352 1.0 1515094 ChemDiv2_001376 Cn1c(=O)c2c(-c3ccccc3CC42CCCCC4)n5c(SCC(=O)N)nnc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O13 compound treatment 0.301 0.0515 2.77 2.7675 1.0 1038377 ChemDiv2_001377 Cc1c(Cc2c(C)n(C)n(c3ccccc3)c2=O)c(=O)n(c4ccccc4)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O14 compound treatment 0.469 0.22 11.8 11.7955 1.0 1638313 ChemDiv2_001378 COc1cc(cc(OC)c1OC)C(Nc2ccccn2)c3c(C)[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O15 compound treatment 0.253 0.0035 0.19 0.1881 1.0 1983972 ChemDiv2_001379 O=S1(=O)CC(C=C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O16 compound treatment 0.47 0.221 11.85 11.8492 1.0 1983973 ChemDiv2_001380 CCOC(=O)c1ccc(NCc2ccccc2O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O17 compound treatment 0.26 0.0105 0.56 0.5642 1.0 1500621 ChemDiv2_001381 CCOc1ccc(CN(C)CCc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O18 compound treatment 0.533 0.283 15.23 15.2347 1.0 1314100 ChemDiv2_001382 Cc1cc(=O)n2nc(cc2[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O19 compound treatment 0.261 0.0115 0.62 0.618 1.0 1983974 ChemDiv2_001383 NC(=N)SCC1CN=C(Nc2ccccc2)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O20 compound treatment 0.259 0.0095 0.51 0.5105 1.0 1912450 ChemDiv2_001384 Cc1[nH]c2ccccc2c1CCCNC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O21 compound treatment 0.254 0.0045 0.24 0.2418 1.0 1675936 ChemDiv2_001385 CN(C)C(=O)COc1cc(C)cc2oc(=O)cc(c3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O22 compound treatment 0.229 -0.0205 -1.1 -1.1016 -1.0 1178417 ChemDiv2_001386 CC1CCN(CC1)c2nc3n(C)c(=O)n(C)c(=O)c3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O23 mock treatment 0.259 0.0095 0.51 0.5105 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 O24 mock treatment 0.256 0.0065 0.35 0.3493 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P01 compound treatment 0.254 0.0045 0.24 0.2418 1.0 1983975 ChemDiv2_001387 CC(Cc1c[nH]c2ccccc12)NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P02 compound treatment 0.312 0.0625 3.36 3.3586 1.0 1983976 ChemDiv2_001388 O=C(OCCN1CCOCC1)C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P03 compound treatment 0.224 -0.0255 -1.37 -1.3703 -1.0 1606542 ChemDiv2_001389 Cn1c(=N)n(CC(=O)N)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P04 compound treatment 0.233 -0.0165 -0.89 -0.8867 -1.0 1629897 ChemDiv2_001390 CC(=O)OC1COC(C(OC(=O)C)C1OC(=O)C)n2ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P05 compound treatment 0.229 -0.0205 -1.1 -1.1016 -1.0 1983977 ChemDiv2_001391 CC1(O)CC(=O)N(O1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P06 compound treatment 0.241 -0.0085 -0.46 -0.4568 -1.0 1983978 ChemDiv2_001392 CCCCC1(CC(CN2CCOCC2)OC1=O)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P07 compound treatment 0.255 0.0055 0.3 0.2956 1.0 1948877 ChemDiv2_001393 Cc1cnn(c1)c2cc(Oc3ccccc3)ncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P08 compound treatment 0.247 -0.0025 -0.13 -0.1343 -1.0 1983979 ChemDiv2_001394 CN(Cc1ccccc1)C2CCN(Cc3ccc(Cl)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P09 compound treatment 0.265 0.0155 0.83 0.8329 1.0 1983980 ChemDiv2_001395 CCC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P10 compound treatment 0.495 0.246 13.19 13.1927 1.0 1983981 ChemDiv2_001396 Cc1nc(cc2c3ccccc3[nH]c12)C(=O)Nc4ccc5nsnc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P11 compound treatment 0.495 0.246 13.19 13.1927 1.0 1983982 ChemDiv2_001397 CCOC(=O)c1ccc(NC(=O)COC(=O)c2cc3ccccc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P12 compound treatment 0.336 0.0865 4.65 4.6483 1.0 1983983 ChemDiv2_001398 O=c1c2CCCCc2[nH]c3c(cnn13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P13 compound treatment 0.473 0.224 12.01 12.0104 1.0 1983984 ChemDiv2_001399 CCc1ccc(o1)C(=O)Nc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P14 compound treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1262997 ChemDiv2_001400 CC(C)Nc1nc(NC(C)C)nc(n1)n2nc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P15 compound treatment 0.325 0.0755 4.06 4.0572 1.0 1983985 ChemDiv2_001401 COc1ccc(Cc2nnc3c4cnn(c5ccc(C)cc5)c4ncn23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P16 compound treatment 0.364 0.115 6.15 6.153 1.0 1463299 ChemDiv2_001402 CC(=O)N(CCC(c1ccco1)c2ccc(C)cc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P17 compound treatment 0.237 -0.0125 -0.67 -0.6717 -1.0 1983986 ChemDiv2_001403 CCN(CC)S(=O)(=O)c1ccc(NC(=O)[C@@H]2CCCC[C@@H]2C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P18 compound treatment 0.242 -0.0075 -0.4 -0.403 -1.0 1549034 ChemDiv2_001404 OCCS(=O)c1ccccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P19 compound treatment 0.258 0.0085 0.46 0.4568 1.0 1983987 ChemDiv2_001405 COc1ccc(cc1)C(=O)c2c(C)n(C)c(=O)n(C)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P20 compound treatment 0.237 -0.0125 -0.67 -0.6717 -1.0 1983988 ChemDiv2_001406 COC(=O)C1C2OC3(C=C2)C1C(=O)N4C3C(C)C(=O)C(C)C4c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P21 compound treatment 0.262 0.0125 0.67 0.6717 1.0 1317588 ChemDiv2_001407 OC(=O)CC(c1ccccc1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P22 compound treatment 0.244 -0.0055 -0.3 -0.2956 -1.0 1464493 ChemDiv2_001408 Cc1cc(Nc2ccccc2C(=O)O)nc3nc4ccccc4c(=O)n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P23 mock treatment 0.248 -0.0015 -0.08 -0.0806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1372 P24 mock treatment 0.246 -0.0035 -0.19 -0.1881 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A01 compound treatment 0.431 0.183 9.86 9.8566 1.0 1983989 ChemDiv2_001409 Cc1nn(c2ccccc2)c3sc(cc13)c4n[nH]c(=S)o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A02 compound treatment 0.266 0.0184 0.99 0.9898 1.0 1983990 ChemDiv2_001410 O=C1CCCc2nc(Nc3nc4ccccc4s3)ncc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A03 compound treatment 0.25 0.00242 0.13 0.13 1.0 1593092 ChemDiv2_001411 Oc1cccc(c1)C2C3=C(NC4=C2C(=O)CCC4)c5ccccc5C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A04 compound treatment 0.309 0.0614 3.3 3.3005 1.0 1983991 ChemDiv2_001412 Fc1ccccc1COC(=O)CN2CC(CC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A05 compound treatment 0.241 -0.00658 -0.35 -0.3536 -1.0 1983992 ChemDiv2_001413 CCn1c(nc2ccccc12)C(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A06 compound treatment 0.296 0.0484 2.6 2.602 1.0 1983993 ChemDiv2_001414 O=C(CCSc1ccccc1)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A07 compound treatment 0.248 4.19E-4 0.02 0.0225 1.0 1933197 ChemDiv2_001415 Cc1cccc(OCCCn2ccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A08 compound treatment 0.259 0.0114 0.61 0.6137 1.0 1983994 ChemDiv2_001416 NC(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A09 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1983995 ChemDiv2_001417 CCN1C(=O)C(NC(=O)C)c2cc(C)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A10 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1983996 ChemDiv2_001418 COc1ccc(CN2CCCC(C2)C(=O)N3CCCC3)c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A11 compound treatment 0.231 -0.0166 -0.89 -0.891 -1.0 1983997 ChemDiv2_001419 CC(CN1CCCC1)OC(=O)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A12 compound treatment 0.234 -0.0136 -0.73 -0.7298 -1.0 1983998 ChemDiv2_001420 OCCN1CCN(CC1)C2CCN(CC2)C3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A13 compound treatment 0.256 0.00842 0.45 0.4524 1.0 1294438 ChemDiv2_001421 Brc1ccc(cc1)C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A14 compound treatment 0.246 -0.00158 -0.08 -0.0849 -1.0 1703377 ChemDiv2_001422 Oc1cccnc1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A15 compound treatment 0.492 0.244 13.13 13.1346 1.0 1983999 ChemDiv2_001423 CC(C)CN1C(=O)c2ccc(cc2C1=O)C(=O)Nc3ccc(OCC(=O)O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A16 compound treatment 0.25 0.00242 0.13 0.13 1.0 1524312 ChemDiv2_001424 CN(C(=O)C)C1(CCCCC1)c2nnnn2CCOC(=O)Nc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A17 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1984000 ChemDiv2_001425 Cc1cc(=O)[nH]c(n1)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A18 compound treatment 0.313 0.0654 3.52 3.5155 1.0 1875389 ChemDiv2_001426 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A19 compound treatment 0.494 0.246 13.24 13.2421 1.0 1984001 ChemDiv2_001427 COc1cccc(NC(=O)CCSc2ccc3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A20 compound treatment 0.452 0.204 10.99 10.9851 1.0 1984002 ChemDiv2_001428 CCSc1nc2c(N)ncn(Cc3ccccc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A21 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1863606 ChemDiv2_001429 CCOc1ccccc1CNc2nc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A22 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1348332 ChemDiv2_001430 Clc1ccc(OCCN2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A23 mock treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 A24 mock treatment 0.274 0.0264 1.42 1.4197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B01 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1984003 ChemDiv2_001431 CCCn1c2ccccc2c3cc(ccc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B02 compound treatment 0.315 0.0674 3.62 3.623 1.0 1984004 ChemDiv2_001432 Cc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)C(=O)NC(C)(C)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B03 compound treatment 0.277 0.0294 1.58 1.5809 1.0 1984005 ChemDiv2_001433 O=C(NC1=NCCS1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B04 compound treatment 0.385 0.137 7.38 7.3846 1.0 1984006 ChemDiv2_001434 COc1ccc2n(C(=O)C)c3C(=NCCc3c2c1)OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B05 compound treatment 0.259 0.0114 0.61 0.6137 1.0 1451471 ChemDiv2_001435 CC1CCc2cc(F)ccc2N1C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B06 compound treatment 0.271 0.0234 1.26 1.2585 1.0 1984007 ChemDiv2_001436 CC(C)C(=O)NC1=NC(=O)CS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B07 compound treatment 0.255 0.00742 0.4 0.3987 1.0 1292114 ChemDiv2_001437 CC(C)(C)C1CCC2(CC1)NC(CO)(CO)CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B08 compound treatment 0.275 0.0274 1.47 1.4735 1.0 1984008 ChemDiv2_001438 O=C1CC(Cc2nc(NCCN3CCOCC3)ncc12)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B09 compound treatment 0.271 0.0234 1.26 1.2585 1.0 1984009 ChemDiv2_001439 CCn1cc(CNC(=O)CCc2ccc(OC)cc2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B10 compound treatment 0.351 0.103 5.56 5.5575 1.0 1984010 ChemDiv2_001440 CCCCN(C)S(=O)(=O)c1cc(ccc1C)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B11 compound treatment 0.268 0.0204 1.1 1.0973 1.0 1984011 ChemDiv2_001441 Oc1ccccc1C(CC(=O)N2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B12 compound treatment 0.338 0.0904 4.86 4.8589 1.0 1301304 ChemDiv2_001442 NC(=O)C1CCN(Cc2c(O)ccc3ccccc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B13 compound treatment 0.479 0.231 12.44 12.436 1.0 1984012 ChemDiv2_001443 Cc1ccc(cc1)C(=O)COC(=O)c2ccc3nc(C)c(C)nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B14 compound treatment 0.238 -0.00958 -0.51 -0.5148 -1.0 1461799 ChemDiv2_001444 CC(=O)N1CCCC1(C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B15 compound treatment 0.398 0.15 8.08 8.0832 1.0 1236151 ChemDiv2_001445 CCC(=O)N(CCC(c1ccco1)c2ccccc2)Cc3ccc(cc3)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B16 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984013 ChemDiv2_001446 C/C=C/c1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B17 compound treatment 0.284 0.0364 1.96 1.9571 1.0 1984014 ChemDiv2_001447 CCCC1C(=C(N)Oc2n[nH]c(CC(=O)OCC)c12)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B18 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1984015 ChemDiv2_001448 CC(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B19 compound treatment 0.313 0.0654 3.52 3.5155 1.0 1647222 ChemDiv2_001449 CC1(C)Cc2c(C#N)c(=O)n(nc2CO1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B20 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1046865 ChemDiv2_001450 OC(=O)C1(CCN(Cc2ccccc2)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B21 compound treatment 0.266 0.0184 0.99 0.9898 1.0 1984016 ChemDiv2_001451 CC(C)Oc1ccc(cc1)C(CC(=O)NC2CCOC(C)(C)C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B22 compound treatment 0.234 -0.0136 -0.73 -0.7298 -1.0 1984017 ChemDiv2_001452 Brc1cnn(Cc2ccc(o2)C(=O)Nc3sc4CCCCCCc4c3C#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B23 mock treatment 0.288 0.0404 2.17 2.1721 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 B24 mock treatment 0.23 -0.0176 -0.94 -0.9447 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C01 compound treatment 0.357 0.109 5.88 5.88 1.0 1984018 ChemDiv2_001453 CCN(CC)c1ncc2C(=O)CC(Cc2n1)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C02 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1984019 ChemDiv2_001454 Cc1ccccc1NC(=O)c2cnc(Nc3nc4ccccc4s3)nc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C03 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1984020 ChemDiv2_001455 Cn1c(=O)n(C)c2cc(CO)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C04 compound treatment 0.335 0.0874 4.7 4.6977 1.0 1617544 ChemDiv2_001456 CCc1nc(NCCO)c(C#N)c2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C05 compound treatment 0.255 0.00742 0.4 0.3987 1.0 1313537 ChemDiv2_001457 OC(c1nc2ccccc2n1CC=C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C06 compound treatment 0.383 0.135 7.28 7.2772 1.0 1984021 ChemDiv2_001458 Clc1ccccc1C(=O)Nc2nonc2c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C07 compound treatment 0.265 0.0174 0.94 0.9361 1.0 1984022 ChemDiv2_001459 COc1ccc(OCCCn2ccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C08 compound treatment 0.3 0.0524 2.82 2.8169 1.0 1984023 ChemDiv2_001460 CN(C)C(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C09 compound treatment 0.252 0.00442 0.24 0.2375 1.0 1984024 ChemDiv2_001461 CC(=O)NC1C(=O)Nc2c1cc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C10 compound treatment 0.31 0.0624 3.35 3.3543 1.0 1984025 ChemDiv2_001462 CN(Cc1ccccc1)C(=O)C2CCCN(Cc3cc(Br)ccc3O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C11 compound treatment 0.253 0.00542 0.29 0.2912 1.0 1984026 ChemDiv2_001463 Cc1cccc(c1)C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C12 compound treatment 0.237 -0.0106 -0.57 -0.5686 -1.0 1984027 ChemDiv2_001464 CN(Cc1ccccc1)C2CCN(Cc3cccnc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C13 compound treatment 0.246 -0.00158 -0.08 -0.0849 -1.0 1984028 ChemDiv2_001465 CC(CN1C(C)CCCC1C)OC(=O)c2cccc(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C14 compound treatment 0.259 0.0114 0.61 0.6137 1.0 1984029 ChemDiv2_001466 CC(C)OC(=O)N(O)c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C15 compound treatment 0.317 0.0694 3.73 3.7305 1.0 1984030 ChemDiv2_001467 Nc1ccc(cc1)c2cc(nc(n2)c3ccccc3)c4cccc(N)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C16 compound treatment 0.273 0.0254 1.37 1.366 1.0 1643424 ChemDiv2_001468 CC(=O)NC1(CCCC1)c2nnnn2CCOC(=O)Nc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C17 compound treatment 0.304 0.0564 3.03 3.0319 1.0 1984031 ChemDiv2_001469 Clc1ccc(COC(=O)CNC(=O)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C18 compound treatment 0.291 0.0434 2.33 2.3333 1.0 1875410 ChemDiv2_001470 Cn1c(nc2ccccc12)c3sc(=S)n(CC=C)c3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C19 compound treatment 0.493 0.245 13.19 13.1883 1.0 1984032 ChemDiv2_001471 O=C(CCSc1ccc2ccccc2n1)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C20 compound treatment 0.254 0.00642 0.34 0.345 1.0 1240163 ChemDiv2_001472 CCOc1ccc(CN(CCO)CCO)cc1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C21 compound treatment 0.257 0.00942 0.51 0.5062 1.0 1863824 ChemDiv2_001473 C(NC1CCCCC1)c2ccccc2OCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C22 compound treatment 0.255 0.00742 0.4 0.3987 1.0 1984033 ChemDiv2_001474 COc1ccc(OCCCN2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C23 mock treatment 0.255 0.00742 0.4 0.3987 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 C24 mock treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D01 compound treatment 0.416 0.168 9.05 9.0505 1.0 1984034 ChemDiv2_001475 COC(=O)c1cc(on1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D02 compound treatment 0.276 0.0284 1.53 1.5272 1.0 1544587 ChemDiv2_001476 CCN(C1SC(=O)NC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D03 compound treatment 0.312 0.0644 3.46 3.4618 1.0 1984035 ChemDiv2_001477 O=C(NCCCn1ccnc1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D04 compound treatment 0.246 -0.00158 -0.08 -0.0849 -1.0 1984036 ChemDiv2_001478 C(N1CCCCC1)c2ccc(Oc3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D05 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1372144 ChemDiv2_001479 Cc1cc(C)n(n1)C(=O)C2CC=CCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D06 compound treatment 0.435 0.187 10.07 10.0715 1.0 1984037 ChemDiv2_001480 COc1ccc(OCC(=O)N2C(C)CCc3cc(F)ccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D07 compound treatment 0.266 0.0184 0.99 0.9898 1.0 1307814 ChemDiv2_001481 OCC1(CO)COC2(CCN(Cc3ccccc3)CC2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D08 compound treatment 0.329 0.0814 4.38 4.3753 1.0 1984038 ChemDiv2_001482 Oc1cc(nn1c2nc3ccccc3[nH]2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D09 compound treatment 0.252 0.00442 0.24 0.2375 1.0 1984039 ChemDiv2_001483 Cc1c(cnn1C)C(=O)Nc2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D10 compound treatment 0.318 0.0704 3.78 3.7842 1.0 1984040 ChemDiv2_001484 Cc1ccc(cc1S(=O)(=O)NCCN2CCOCC2)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D11 compound treatment 0.428 0.18 9.7 9.6954 1.0 1984041 ChemDiv2_001485 CC(C)NS(=O)(=O)c1ccc(OCC(=O)NCc2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D12 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1673067 ChemDiv2_001486 Cc1ccc(cc1)S(=O)(=O)CC(=O)NC2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D13 compound treatment 0.246 -0.00158 -0.08 -0.0849 -1.0 1984042 ChemDiv2_001487 O=C1CCCN1CC2CCCNC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D14 compound treatment 0.292 0.0444 2.39 2.387 1.0 1984043 ChemDiv2_001488 COc1ccc(cc1)N2C(=O)CC2(C#N)c3ccc(OCc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D15 compound treatment 0.265 0.0174 0.94 0.9361 1.0 1984044 ChemDiv2_001489 Fc1ccc(cc1)C(CC(=O)N2CCCCC2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D16 compound treatment 0.254 0.00642 0.34 0.345 1.0 1984045 ChemDiv2_001490 CC(C)c1[nH]nc2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D17 compound treatment 0.397 0.149 8.03 8.0295 1.0 1984046 ChemDiv2_001491 CC1C(=C(N)Oc2n[nH]c(CSc3ccc(C)cc3)c12)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D18 compound treatment 0.253 0.00542 0.29 0.2912 1.0 1984047 ChemDiv2_001492 CCC(NCc1cccnc1)c2ccc(OC)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D19 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1984048 ChemDiv2_001493 C(NC1CCCCC1)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D20 compound treatment 0.275 0.0274 1.47 1.4735 1.0 1984049 ChemDiv2_001494 CN(C)C(=O)c1cc(c(Cl)cc1N2CCCC2)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D21 compound treatment 0.265 0.0174 0.94 0.9361 1.0 1984050 ChemDiv2_001495 CCN(CC)C(=O)CC(c1ccco1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D22 compound treatment 0.418 0.17 9.16 9.158 1.0 1696252 ChemDiv2_001496 COC(=O)c1ccc(Cn2nc(C)c(Br)c2C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D23 mock treatment 0.251 0.00342 0.18 0.1837 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 D24 mock treatment 0.235 -0.0126 -0.68 -0.6761 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E01 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1984051 ChemDiv2_001497 Cc1ccc(cc1)C2CC(=O)c3cnc(nc3C2)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E02 compound treatment 0.265 0.0174 0.94 0.9361 1.0 1984052 ChemDiv2_001498 COc1ccc2[nH]cc(CCSC(=N)N)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E03 compound treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1913637 ChemDiv2_001499 Cc1n[nH]c(C)c1c2c(C)n[nH]c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E04 compound treatment 0.275 0.0274 1.47 1.4735 1.0 1741216 ChemDiv2_001500 Oc1ncnc2c1sc3nc(c4ccco4)c5CCCCc5c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E05 compound treatment 0.232 -0.0156 -0.84 -0.8373 -1.0 1548944 ChemDiv2_001501 OC(=O)CCCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E06 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1497229 ChemDiv2_001502 CC(NC1CCOC(C)(C)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E07 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1984053 ChemDiv2_001503 COc1ccccc1n2c(SC)nc(O)cc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E08 compound treatment 0.534 0.286 15.39 15.3916 1.0 1984054 ChemDiv2_001504 O=C(Cn1nc2-c3ccccc3-c4cccc(c1=O)c42)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E09 compound treatment 0.241 -0.00658 -0.35 -0.3536 -1.0 1984055 ChemDiv2_001505 CCc1ccc2NC(=O)C(NC(=O)C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E10 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1984056 ChemDiv2_001506 CC(C)N1CCCC(C1)C(=O)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E11 compound treatment 0.242 -0.00558 -0.3 -0.2999 -1.0 1984057 ChemDiv2_001507 CC(CN1CCCC1)OC(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E12 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1984058 ChemDiv2_001508 CCOC(=O)N1CCC(CC1)N2CCCC(C2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E13 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1984059 ChemDiv2_001509 Fc1ccc(cc1)C(=O)NCCN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E14 compound treatment 0.248 4.19E-4 0.02 0.0225 1.0 1404703 ChemDiv2_001510 CC(C)C(CO)NC(=O)Oc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E15 compound treatment 0.417 0.169 9.1 9.1042 1.0 1984060 ChemDiv2_001511 CCN1C(=O)c2ccc(cc2C1=O)C(=O)Nc3cc(OC)c(OC)cc3C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E16 compound treatment 0.291 0.0434 2.33 2.3333 1.0 1642451 ChemDiv2_001512 COCC(=O)NC1(CCCCC1)c2nnnn2CCOC(=O)Nc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E17 compound treatment 0.346 0.0984 5.29 5.2889 1.0 1984061 ChemDiv2_001513 Clc1ccc(COC(=O)CNC(=O)c2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E18 compound treatment 0.282 0.0344 1.85 1.8496 1.0 1984062 ChemDiv2_001514 CCOC(=O)C(N1CCN(CC1)c2ccccc2F)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E19 compound treatment 0.534 0.286 15.39 15.3916 1.0 1984063 ChemDiv2_001515 COc1cccc(NC(=O)CCSc2nnc3scc(c4ccccc4)n23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E20 compound treatment 0.29 0.0424 2.28 2.2795 1.0 1984064 ChemDiv2_001516 COC(=O)CN1C(=O)c2cccc3cccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E21 compound treatment 0.289 0.0414 2.23 2.2258 1.0 1863904 ChemDiv2_001517 Oc1ccc(NCc2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E22 compound treatment 0.266 0.0184 0.99 0.9898 1.0 1094401 ChemDiv2_001518 Cn1nc(nc2c(=O)n(C)c(=O)nc12)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E23 mock treatment 0.248 4.19E-4 0.02 0.0225 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 E24 mock treatment 0.25 0.00242 0.13 0.13 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F01 compound treatment 0.34 0.0924 4.97 4.9664 1.0 1984065 ChemDiv2_001519 COC(=O)c1cc(/C=C/c2ccccc2)on1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F02 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1867795 ChemDiv2_001520 O=c1c(nsn1Cc2ccccc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F03 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1680816 ChemDiv2_001521 CC(C)OC(=O)c1cc(NC(=O)C2C(C3CCC2O3)C(=O)O)cc(c1)C(=O)OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F04 compound treatment 0.542 0.294 15.82 15.8215 1.0 1281950 ChemDiv2_001522 OC(=O)COc1ccc2occ(C(=O)c3cccs3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F05 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1879692 ChemDiv2_001523 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCC(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F06 compound treatment 0.261 0.0134 0.72 0.7211 1.0 1984066 ChemDiv2_001524 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3C(C)CCc4cc(F)ccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F07 compound treatment 0.252 0.00442 0.24 0.2375 1.0 1880695 ChemDiv2_001525 CC1CN(C(C)CN1C(=O)c2ccc3OCOc3c2)C(=O)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F08 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1984067 ChemDiv2_001526 CCn1c(Sc2c(C)c3cc4OCOc4cc3[nH]c2=O)nnc1c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F09 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984068 ChemDiv2_001527 OC(=O)C1C(C2OC1C=C2)C(=O)NC3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F10 compound treatment 0.256 0.00842 0.45 0.4524 1.0 1984069 ChemDiv2_001528 CC(C)NC(=O)CC1OC(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F11 compound treatment 0.258 0.0104 0.56 0.5599 1.0 1984070 ChemDiv2_001529 Nc1ccc(Cc2nc3cc(ccc3[nH]2)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F12 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1478698 ChemDiv2_001530 Cc1ccoc1C(=O)N2CCCCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F13 compound treatment 0.265 0.0174 0.94 0.9361 1.0 1967343 ChemDiv2_001531 OC(=O)CCC(=O)N1CCC(=CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F14 compound treatment 0.26 0.0124 0.67 0.6674 1.0 1984071 ChemDiv2_001532 CC(=O)N1C(CC(=O)OC1c2ccc3OCOc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F15 compound treatment 0.276 0.0284 1.53 1.5272 1.0 1293997 ChemDiv2_001533 CN(c1nc(C)cc2nnnn12)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F16 compound treatment 0.271 0.0234 1.26 1.2585 1.0 1130465 ChemDiv2_001534 C(CN1CCNCC1)NC2CCCCCCCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F17 compound treatment 0.406 0.158 8.51 8.5131 1.0 1984072 ChemDiv2_001535 CC(C)(C)C1CC=C2C(C1)C(CCc3ccccc3)C(C#N)(C#N)C(=C2C#N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F18 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1984073 ChemDiv2_001536 CN(C)S(=O)(=O)c1cc(C(=O)O)c(cc1Cl)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F19 compound treatment 0.264 0.0164 0.88 0.8823 1.0 1984074 ChemDiv2_001537 COc1cccc(C2OC(=O)c3ccccc3N2C(=O)C)c1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F20 compound treatment 0.294 0.0464 2.49 2.4945 1.0 1984075 ChemDiv2_001538 Cc1n[nH]c(C)c1Cc2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F21 compound treatment 0.252 0.00442 0.24 0.2375 1.0 1984076 ChemDiv2_001539 Cc1cc(C)n(n1)c2nc3ccccc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F22 compound treatment 0.3 0.0524 2.82 2.8169 1.0 1501223 ChemDiv2_001540 Cc1nn(Cc2ccc(o2)C(=O)NC(C)(C)C)c(C)c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F23 mock treatment 0.248 4.19E-4 0.02 0.0225 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 F24 mock treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G01 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1984077 ChemDiv2_001541 COC(=O)Cc1cc(O)n(n1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G02 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1984078 ChemDiv2_001542 Cc1ccc(O)c(c1)C(CC(=O)NC2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G03 compound treatment 0.551 0.303 16.31 16.3051 1.0 1681451 ChemDiv2_001543 OC(=O)c1ccc2C(=O)N(Cc3ccccc3)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G04 compound treatment 0.228 -0.0196 -1.05 -1.0522 -1.0 1424507 ChemDiv2_001544 CC1(C)Cc2c(C(=O)N)c(nc(c3ccccc3)c2CO1)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G05 compound treatment 0.246 -0.00158 -0.08 -0.0849 -1.0 1708860 ChemDiv2_001545 Cc1ccccc1Cn2c(=O)[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G06 compound treatment 0.253 0.00542 0.29 0.2912 1.0 1984079 ChemDiv2_001546 OC(CC#CC(O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G07 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1190650 ChemDiv2_001547 CCSc1nc(O)cc(=O)n1c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G08 compound treatment 0.242 -0.00558 -0.3 -0.2999 -1.0 1984080 ChemDiv2_001548 CN1CCC(CC=C)(CC1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G09 compound treatment 0.257 0.00942 0.51 0.5062 1.0 1984081 ChemDiv2_001549 CCc1ccc2[nH]c3sc(C)nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G10 compound treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1984082 ChemDiv2_001550 CCCN1CCC(CC1)N2CCCC(C2)C(=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G11 compound treatment 0.255 0.00742 0.4 0.3987 1.0 1728617 ChemDiv2_001551 Cc1ccc(cc1)C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G12 compound treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1984083 ChemDiv2_001552 COc1cc(CN2CCC(CC2)N3CCN(C)CC3)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G13 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984084 ChemDiv2_001553 CC(CN1C(C)CCCC1C)OC(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G14 compound treatment 0.273 0.0254 1.37 1.366 1.0 1183773 ChemDiv2_001554 CCN(CC)CCOc1c(Br)ccc2c1sc3nc4CCCn4c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G15 compound treatment 0.27 0.0224 1.2 1.2048 1.0 1984085 ChemDiv2_001555 O/N=C/Cc1[nH]c2ccccc2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G16 compound treatment 0.379 0.131 7.06 7.0622 1.0 1256360 ChemDiv2_001556 Clc1ccc(NC(=O)OCCn2nnnc2C(N3CCOCC3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G17 compound treatment 0.596 0.348 18.72 18.7233 1.0 1984086 ChemDiv2_001557 CCOC(=O)C1CN(CC1=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G18 compound treatment 0.424 0.176 9.48 9.4804 1.0 1984087 ChemDiv2_001558 Clc1cccc(NC(=O)OCc2ccc3OCOc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G19 compound treatment 0.485 0.237 12.76 12.7584 1.0 1984088 ChemDiv2_001559 Cc1ccc(NC(=O)CCSc2nnc3scc(c4ccccc4)n23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G20 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984089 ChemDiv2_001560 CCCC1(CN2CC3(C)CN(C1)C(=O)c4ccccc4C2=O)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G21 compound treatment 0.237 -0.0106 -0.57 -0.5686 -1.0 1984090 ChemDiv2_001561 CN1CC2(CN(C)CC(C1)(C2)C(=O)c3ccccc3)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G22 compound treatment 0.361 0.113 6.09 6.0949 1.0 1984091 ChemDiv2_001562 CCOC(=O)C1CCN(CC1)C(=O)CSCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G23 mock treatment 0.266 0.0184 0.99 0.9898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 G24 mock treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H01 compound treatment 0.499 0.251 13.51 13.5108 1.0 1984092 ChemDiv2_001563 COC(=O)c1cc([nH]n1)c2ccc(OC)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H02 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1984093 ChemDiv2_001564 O=C1CSC(=O)N1C/C=C/CN2C(=O)CSC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H03 compound treatment 0.445 0.197 10.61 10.6089 1.0 1984094 ChemDiv2_001565 CCOC(=O)CCc1cccc2C(=O)CCc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H04 compound treatment 0.25 0.00242 0.13 0.13 1.0 1336191 ChemDiv2_001566 CN(C)CCn1c(cc2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H05 compound treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1984095 ChemDiv2_001567 OC(=O)C1C(C2CC1C=C2)C(=O)NCCCn3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H06 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1984096 ChemDiv2_001568 CCC(=O)N1C(Oc2nc(SCC=C)nnc2-c3ccccc13)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H07 compound treatment 0.405 0.157 8.46 8.4594 1.0 1984097 ChemDiv2_001569 Fc1ccc(OCc2ccc(o2)C(=O)NC3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H08 compound treatment 0.308 0.0604 3.25 3.2468 1.0 1984098 ChemDiv2_001570 Cc1cc(=O)[nH]c(Sc2c(C)c3cc4OCOc4cc3[nH]c2=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H09 compound treatment 0.375 0.127 6.85 6.8472 1.0 1984099 ChemDiv2_001571 O=c1[nH]c(nc2ccccc12)c3ccc4nsnc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H10 compound treatment 0.261 0.0134 0.72 0.7211 1.0 1984100 ChemDiv2_001572 CC(Sc1nc(N)cc(=O)[nH]1)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H11 compound treatment 0.438 0.19 10.23 10.2327 1.0 1984101 ChemDiv2_001573 Cc1ccc2nc(Cc3ccc(N)cc3)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H12 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1738525 ChemDiv2_001574 Cc1ccc(o1)C(=O)N2CCCCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H13 compound treatment 0.287 0.0394 2.12 2.1183 1.0 1984102 ChemDiv2_001575 OC(=O)C1CCCCC1C(=O)N2CCC(=CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H14 compound treatment 0.248 4.19E-4 0.02 0.0225 1.0 1267459 ChemDiv2_001576 CCN1CCCC(C1)OC(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H15 compound treatment 0.487 0.239 12.87 12.8659 1.0 1984103 ChemDiv2_001577 Cc1ccc(cc1)c2cccc(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H16 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1269127 ChemDiv2_001578 OC(=O)c1ccc2CN(CC=C)Cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H17 compound treatment 0.471 0.223 12.01 12.0061 1.0 1984104 ChemDiv2_001579 CNc1nc2[nH]c(=O)cc(O)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H18 compound treatment 0.324 0.0764 4.11 4.1066 1.0 1984105 ChemDiv2_001580 O=C(NC1CCCCC1)c2ccc(CNc3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H19 compound treatment 0.412 0.164 8.84 8.8356 1.0 1984106 ChemDiv2_001581 CC(C)COc1ccc(cc1)C(=O)OCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H20 compound treatment 0.291 0.0434 2.33 2.3333 1.0 1984107 ChemDiv2_001582 Brc1cnn(c1)C(=O)c2ccc(OCC=C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H21 compound treatment 0.517 0.269 14.48 14.478 1.0 1984108 ChemDiv2_001583 Nc1cc(O)nc2nnc(SCc3ccccc3)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H22 compound treatment 0.433 0.185 9.96 9.964 1.0 1409979 ChemDiv2_001584 O=C(NCc1cccnc1)c2ccc(COc3ccc4CCCc4c3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H23 mock treatment 0.258 0.0104 0.56 0.5599 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 H24 mock treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I01 compound treatment 0.424 0.176 9.48 9.4804 1.0 1984109 ChemDiv2_001585 Clc1ccc2[nH]c(=O)c(SCC(=O)N3CCCCC3)c(c4ccccc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I02 compound treatment 0.268 0.0204 1.1 1.0973 1.0 1984110 ChemDiv2_001586 CCCN(CCC)C(=O)CC(c1ccccc1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I03 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1481274 ChemDiv2_001587 CCOC(=O)C(Nc1cccc(F)c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I04 compound treatment 0.254 0.00642 0.34 0.345 1.0 1984111 ChemDiv2_001588 CCc1nc2sc3c(SCC(=O)N)ncnc3c2c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I05 compound treatment 0.282 0.0344 1.85 1.8496 1.0 1612434 ChemDiv2_001589 Cc1cccc(Cn2c(=O)[nH]c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I06 compound treatment 0.312 0.0644 3.46 3.4618 1.0 1984112 ChemDiv2_001590 OC(=O)c1ccc(CN2CCN(Cc3ccc(o3)C(=O)O)CC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I07 compound treatment 0.238 -0.00958 -0.51 -0.5148 -1.0 1594335 ChemDiv2_001591 CCN(CC)C(=O)CSc1nc(O)cc(=O)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I08 compound treatment 0.248 4.19E-4 0.02 0.0225 1.0 1984113 ChemDiv2_001592 C1CC2C(O1)c3ccccc3NC2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I09 compound treatment 0.341 0.0934 5.02 5.0202 1.0 1984114 ChemDiv2_001593 CCc1ccc2n(C)c3sc(C)nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I10 compound treatment 0.269 0.0214 1.15 1.151 1.0 1984115 ChemDiv2_001594 CC1CN(CC(C)O1)C2CCN(Cc3ccccn3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I11 compound treatment 0.238 -0.00958 -0.51 -0.5148 -1.0 1984116 ChemDiv2_001595 CC(CN1CCCC1)OC(=O)c2ccccc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I12 compound treatment 0.344 0.0964 5.18 5.1814 1.0 1984117 ChemDiv2_001596 OC(=O)c1cccc(CSc2ncccn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I13 compound treatment 0.565 0.317 17.06 17.0575 1.0 1984118 ChemDiv2_001597 OCCSc1nnc(Nc2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I14 compound treatment 0.532 0.284 15.28 15.2841 1.0 1633374 ChemDiv2_001598 C1CC=C(C1)c2ccc3n4CCNC5CCCc(c54)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I15 compound treatment 0.417 0.169 9.1 9.1042 1.0 1275561 ChemDiv2_001599 CN(C)CCn1c(N)c(c2nc3ccccc3n2C)c4nc(C#N)c(C#N)nc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I16 compound treatment 0.51 0.262 14.1 14.1019 1.0 1984119 ChemDiv2_001600 Cn1c(=O)n(C)c2cc(ccc12)C3C(=C(N)Oc4c3ccc5ccccc45)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I17 compound treatment 0.285 0.0374 2.01 2.0108 1.0 1404680 ChemDiv2_001601 CCOC(=O)c1nn(c2ccc(OC)cc2)c(=O)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I18 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1984120 ChemDiv2_001602 Clc1ccc(OCC(=O)OCc2csc3N4CCC(CC4)c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I19 compound treatment 0.37 0.122 6.58 6.5786 1.0 1984121 ChemDiv2_001603 O=C(CCSc1nnc2scc(c3ccccc3)n12)NCc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I20 compound treatment 0.276 0.0284 1.53 1.5272 1.0 1984122 ChemDiv2_001604 Cc1ccc(C(CC(=O)N2CCNCC2)c3ccccc3)c(O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I21 compound treatment 0.268 0.0204 1.1 1.0973 1.0 1984123 ChemDiv2_001605 CC(C)Cn1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I22 compound treatment 0.322 0.0744 4.0 3.9991 1.0 1984124 ChemDiv2_001606 CCOC(=O)C1CCCN(C1)C(=O)CCC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I23 mock treatment 0.264 0.0164 0.88 0.8823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 I24 mock treatment 0.248 4.19E-4 0.02 0.0225 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J01 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1984125 ChemDiv2_001607 COC(=O)C1=C(C(c2ccccc2)n3nnnc3N1)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J02 compound treatment 0.246 -0.00158 -0.08 -0.0849 -1.0 1984126 ChemDiv2_001608 OC[C@H]1O[C@H](CC1O)n2ccc(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J03 compound treatment 0.321 0.0734 3.95 3.9454 1.0 1393198 ChemDiv2_001609 COc1ccc2C3OCc4ccccc4N3C(=O)c2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J04 compound treatment 0.256 0.00842 0.45 0.4524 1.0 1686878 ChemDiv2_001610 CN(C)CCn1c(cc2ccccc12)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J05 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1225747 ChemDiv2_001611 Cc1occc1C(=O)N(Cc2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J06 compound treatment 0.232 -0.0156 -0.84 -0.8373 -1.0 1984127 ChemDiv2_001612 CC(C(=O)O)n1cnc2sc(C)c(c3ccc(C)c(C)c3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J07 compound treatment 0.495 0.247 13.3 13.2958 1.0 1984128 ChemDiv2_001613 Fc1ccc(OCc2ccc(o2)C(=O)n3cccn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J08 compound treatment 0.271 0.0234 1.26 1.2585 1.0 1984129 ChemDiv2_001614 COC(=O)c1cccc(NC(=O)C2(CCOCC2)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J09 compound treatment 0.256 0.00842 0.45 0.4524 1.0 1984130 ChemDiv2_001615 OC(=O)CCc1c([nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J10 compound treatment 0.253 0.00542 0.29 0.2912 1.0 1984131 ChemDiv2_001616 CC(NC(=O)CSc1nc(=O)c(NC(=O)C)c(O)n1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J11 compound treatment 0.388 0.14 7.55 7.5458 1.0 1318032 ChemDiv2_001617 c1ccc(nc1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J12 compound treatment 0.269 0.0214 1.15 1.151 1.0 1595730 ChemDiv2_001618 Cc1cc(=O)n([nH]1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J13 compound treatment 0.272 0.0244 1.31 1.3122 1.0 1984132 ChemDiv2_001619 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCC(=CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J14 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1669684 ChemDiv2_001620 O=C1C2CCCC1C(CC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J15 compound treatment 0.273 0.0254 1.37 1.366 1.0 1080731 ChemDiv2_001621 OC(=O)C1CC1c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J16 compound treatment 0.258 0.0104 0.56 0.5599 1.0 1055889 ChemDiv2_001622 C(Nc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J17 compound treatment 0.554 0.306 16.47 16.4663 1.0 1984133 ChemDiv2_001623 CNc1sc2c(O)cc(=O)[nH]c2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J18 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1984134 ChemDiv2_001624 Cc1cccc(C)c1NC(=O)c2ccc(CN3CCCCC3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J19 compound treatment 0.255 0.00742 0.4 0.3987 1.0 1984135 ChemDiv2_001625 CN(C)c1ccc(CNC2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J20 compound treatment 0.46 0.212 11.41 11.415 1.0 1377485 ChemDiv2_001626 CCCNC(=O)c1ccc(COc2ccc3ccccc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J21 compound treatment 0.512 0.264 14.21 14.2093 1.0 1984136 ChemDiv2_001627 COc1ccc(NC(=O)CSc2nnc3nc(O)cc(N)n23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J22 compound treatment 0.353 0.105 5.67 5.665 1.0 1627745 ChemDiv2_001628 COC(=O)c1ccc(COc2ccc3CCCc3c2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J23 mock treatment 0.255 0.00742 0.4 0.3987 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 J24 mock treatment 0.234 -0.0136 -0.73 -0.7298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K01 compound treatment 0.284 0.0364 1.96 1.9571 1.0 1984137 ChemDiv2_001629 CCOC(=O)COC1=C(C(=O)c2ccccc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K02 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1984138 ChemDiv2_001630 OC(=O)CC(c1ccccc1)c2cc(Br)ccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K03 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984139 ChemDiv2_001631 CCOC(=O)C(Nc1ccc2OCCOc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K04 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984140 ChemDiv2_001632 Cc1cc(Oc2ccccc2)nc(Oc3ccc(O)nn3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K05 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1486030 ChemDiv2_001633 COc1ccc(cc1)C(=O)C(C)(C)NO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K06 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1984141 ChemDiv2_001634 Cc1ccccc1n2nnc3c(=O)oc4ccccc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K07 compound treatment 0.237 -0.0106 -0.57 -0.5686 -1.0 1596769 ChemDiv2_001635 CCN(CC)C(=O)CSc1nc(O)cc(=O)n1c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K08 compound treatment 0.254 0.00642 0.34 0.345 1.0 1984142 ChemDiv2_001636 Cc1cccc(c1)N2C(CC=C)c3cccc(C(=O)O)c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K09 compound treatment 0.355 0.107 5.77 5.7725 1.0 1984143 ChemDiv2_001637 CCn1c(C)nc2C(=O)c3ccccc3C(=O)c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K10 compound treatment 0.238 -0.00958 -0.51 -0.5148 -1.0 1984144 ChemDiv2_001638 CC1CN(CC(C)O1)C2CCN(CC3CC4CC3C=C4)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K11 compound treatment 0.258 0.0104 0.56 0.5599 1.0 1984145 ChemDiv2_001639 Brc1ccccc1C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K12 compound treatment 0.503 0.255 13.73 13.7257 1.0 1984146 ChemDiv2_001640 Cc1ccc(cc1)C(=O)Nc2c(C#N)sc(=N)n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K13 compound treatment 0.258 0.0104 0.56 0.5599 1.0 1984147 ChemDiv2_001641 COC(=O)C1C(c2c(OC1=O)ccc3ccccc23)C(C)(C)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K14 compound treatment 0.339 0.0914 4.91 4.9127 1.0 1526046 ChemDiv2_001642 C1CC2NCCn3c2c(C1)c4cc(ccc34)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K15 compound treatment 0.256 0.00842 0.45 0.4524 1.0 1984148 ChemDiv2_001643 O/N=C/c1cccn1c2cccc(c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K16 compound treatment 0.268 0.0204 1.1 1.0973 1.0 1984149 ChemDiv2_001644 CC(Oc1ccc(F)cc1)C(=O)NCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K17 compound treatment 0.26 0.0124 0.67 0.6674 1.0 1500472 ChemDiv2_001645 CC1CCN(Cc2c(O)ccc3ccccc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K18 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984150 ChemDiv2_001646 CC(=O)N1CC2C(C3CCN2CC3)N(C(=O)C)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K19 compound treatment 0.287 0.0394 2.12 2.1183 1.0 1249301 ChemDiv2_001647 COc1ccc(CNc2ccc3[nH]c(=O)[nH]c3c2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K20 compound treatment 0.292 0.0444 2.39 2.387 1.0 1984151 ChemDiv2_001648 COc1ccc(CCNC(=O)CC(c2ccccc2)c3cc(C)ccc3O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K21 compound treatment 0.497 0.249 13.4 13.4033 1.0 1984152 ChemDiv2_001649 CC(=O)OC(COc1ccccc1C)Cn2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K22 compound treatment 0.355 0.107 5.77 5.7725 1.0 1984153 ChemDiv2_001650 COC(=O)C1CCN(CC1)C(=O)CCC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K23 mock treatment 0.252 0.00442 0.24 0.2375 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 K24 mock treatment 0.256 0.00842 0.45 0.4524 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L01 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1984154 ChemDiv2_001651 CCOC(=O)NC(C)C1CC2CCC1C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L02 compound treatment 0.531 0.283 15.23 15.2304 1.0 1984155 ChemDiv2_001652 Brc1ccc(cc1)c2n[nH]c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L03 compound treatment 0.372 0.124 6.69 6.686 1.0 1984156 ChemDiv2_001653 Cc1cc(Cl)ccc1OCCCC(=O)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L04 compound treatment 0.505 0.257 13.83 13.8332 1.0 1984157 ChemDiv2_001654 Nc1nnc2c3ccccc3[nH]c2c1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L05 compound treatment 0.294 0.0464 2.49 2.4945 1.0 1153443 ChemDiv2_001655 CC1CN(C(C)CN1C(=O)CCc2ccccc2)C(=O)CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L06 compound treatment 0.248 4.19E-4 0.02 0.0225 1.0 1872413 ChemDiv2_001656 Clc1ccc(Oc2cccc3C(=O)N(CC4CCCO4)C(=O)c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L07 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1881224 ChemDiv2_001657 Cc1ccc(Cn2ccc(NC(=O)C3C(C4CCC3C4)C(=O)O)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L08 compound treatment 0.256 0.00842 0.45 0.4524 1.0 1984158 ChemDiv2_001658 Cn1cnc2cc(ccc12)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L09 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1984159 ChemDiv2_001659 CCOc1ccc(Cc2nc(C)c(CC(=O)N3CCCCC3)c(O)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L10 compound treatment 0.388 0.14 7.55 7.5458 1.0 1984160 ChemDiv2_001660 CC1SC(NC1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L11 compound treatment 0.473 0.225 12.11 12.1136 1.0 1984161 ChemDiv2_001661 c1ccc2oc(nc2c1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L12 compound treatment 0.263 0.0154 0.83 0.8286 1.0 1428359 ChemDiv2_001662 COc1ccc(cc1)n2[nH]c(C)cc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L13 compound treatment 0.257 0.00942 0.51 0.5062 1.0 1984162 ChemDiv2_001663 OC(=O)C1CCCCC1C(=O)NCCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L14 compound treatment 0.235 -0.0126 -0.68 -0.6761 -1.0 1705778 ChemDiv2_001664 C(NCc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L15 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1609544 ChemDiv2_001665 CC(C)N1CC2(CN(CC(C1)(C2=O)c3ccccc3)C(C)C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L16 compound treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1984163 ChemDiv2_001666 OC1C2CCCC1C(CC2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L17 compound treatment 0.298 0.0504 2.71 2.7094 1.0 1984164 ChemDiv2_001667 CCCCc1[nH]nc2OC(=C(C#N)C3(CCN(C)CC3)c12)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L18 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1984165 ChemDiv2_001668 COC(=O)c1cc(c(Cl)cc1N2CCCC2)S(=O)(=O)CC(N3CCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L19 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1984166 ChemDiv2_001669 CC(=O)N1C(OC(=O)c2ccccc12)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L20 compound treatment 0.25 0.00242 0.13 0.13 1.0 1984167 ChemDiv2_001670 CN1Cc2cccc(C(=O)O)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L21 compound treatment 0.271 0.0234 1.26 1.2585 1.0 1098939 ChemDiv2_001671 Nc1c(C#N)sc(=S)n1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L22 compound treatment 0.452 0.204 10.99 10.9851 1.0 1650483 ChemDiv2_001672 Clc1ccc(OCc2ccc(o2)C(=O)NCc3ccccn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L23 mock treatment 0.253 0.00542 0.29 0.2912 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 L24 mock treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M01 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1703028 ChemDiv2_001673 OC1=C(C(=O)c2ccccc2C1=O)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M02 compound treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1984168 ChemDiv2_001674 NC(=N)SCC1COc2ccccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M03 compound treatment 0.333 0.0854 4.59 4.5903 1.0 1233868 ChemDiv2_001675 COCn1c(nc2ccccc12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M04 compound treatment 0.494 0.246 13.24 13.2421 1.0 1984169 ChemDiv2_001676 COc1ccccc1OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M05 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1984170 ChemDiv2_001677 CC1(C)OC(=O)CC1C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M06 compound treatment 0.257 0.00942 0.51 0.5062 1.0 1984171 ChemDiv2_001678 Cc1ccc(cc1)n2nnc3c(=O)oc4ccccc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M07 compound treatment 0.455 0.207 11.15 11.1463 1.0 1984172 ChemDiv2_001679 CCOC(=O)c1cc2C(=O)c3ccccc3-n2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M08 compound treatment 0.257 0.00942 0.51 0.5062 1.0 1984173 ChemDiv2_001680 COc1ccc(cc1OC)C(=O)CSc2nc(O)c3c(C)cc(C)nc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M09 compound treatment 0.272 0.0244 1.31 1.3122 1.0 1984174 ChemDiv2_001681 Nc1nc2c3ccccc3nc(Cc4ccccc4)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M10 compound treatment 0.232 -0.0156 -0.84 -0.8373 -1.0 1984175 ChemDiv2_001682 CC1CN(CC(C)O1)C2CCN(CC2)C3CC4CCC3C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M11 compound treatment 0.241 -0.00658 -0.35 -0.3536 -1.0 1984176 ChemDiv2_001683 CC(CN1CCCC1)OC(=O)c2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M12 compound treatment 0.311 0.0634 3.41 3.408 1.0 1784767 ChemDiv2_001684 CCOc1ccc2[nH]c(C)cc(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M13 compound treatment 0.274 0.0264 1.42 1.4197 1.0 1984177 ChemDiv2_001685 CCOC(=O)C1C(c2cc(Br)ccc2OC1=O)C3(CCCC3)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M14 compound treatment 0.325 0.0774 4.16 4.1604 1.0 1157140 ChemDiv2_001686 CC(O)CNC(=O)COc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M15 compound treatment 0.377 0.129 6.95 6.9547 1.0 1984178 ChemDiv2_001687 CCOC(=O)c1cnc2sccn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M16 compound treatment 0.519 0.271 14.59 14.5855 1.0 1984179 ChemDiv2_001688 COc1ccc(cc1)c2csc(n2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M17 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1984180 ChemDiv2_001689 OC(=O)C1CC(=O)NC(=N)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M18 compound treatment 0.255 0.00742 0.4 0.3987 1.0 1984181 ChemDiv2_001690 CNC(=O)Cn1c(=O)n(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M19 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1863475 ChemDiv2_001691 Clc1ccc(COc2ccc(CNc3ccc4[nH]c(=O)[nH]c4c3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M20 compound treatment 0.264 0.0164 0.88 0.8823 1.0 1984182 ChemDiv2_001692 Cc1cccc(C)c1OCCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M21 compound treatment 0.249 0.00142 0.08 0.0763 1.0 1610923 ChemDiv2_001693 COc1ccc(cc1)N(C(C)C(=O)O)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M22 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1984183 ChemDiv2_001694 Cc1ccc(CC(=O)NCCCn2ccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M23 mock treatment 0.252 0.00442 0.24 0.2375 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 M24 mock treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N01 compound treatment 0.259 0.0114 0.61 0.6137 1.0 1984184 ChemDiv2_001695 COC(=O)NCCc1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N02 compound treatment 0.39 0.142 7.65 7.6533 1.0 1984185 ChemDiv2_001696 COc1ccc2c(c1)sc3nc(=O)ccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N03 compound treatment 0.258 0.0104 0.56 0.5599 1.0 1546234 ChemDiv2_001697 OC(=O)C1CCCCC1C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N04 compound treatment 0.309 0.0614 3.3 3.3005 1.0 1984186 ChemDiv2_001698 CC(Cc1c[nH]c2ccccc12)Nc3ccc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N05 compound treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1294432 ChemDiv2_001699 OC(=O)C1C(C2CCC1O2)C(=O)NCCC(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N06 compound treatment 0.402 0.154 8.3 8.2982 1.0 1984187 ChemDiv2_001700 COc1ccc(CCNc2ncc3C(=O)CC(Cc3n2)c4ccc(C)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N07 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1881304 ChemDiv2_001701 OC(=O)CCC(=O)Nc1ccn(Cc2ccc(Cl)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N08 compound treatment 0.31 0.0624 3.35 3.3543 1.0 1984188 ChemDiv2_001702 Cc1ccc(cc1S(=O)(=O)N2CCCC2)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N09 compound treatment 0.26 0.0124 0.67 0.6674 1.0 1984189 ChemDiv2_001703 Oc1ccccc1C(CC(=O)N2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N10 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1310481 ChemDiv2_001704 COc1ccc(N)c2nc(C)c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N11 compound treatment 0.31 0.0624 3.35 3.3543 1.0 1984190 ChemDiv2_001705 Clc1ccc(NC2CS(=O)(=O)CC2NCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N12 compound treatment 0.258 0.0104 0.56 0.5599 1.0 1984191 ChemDiv2_001706 CCCC(CCC)n1nc(O)c2c(C)cc(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N13 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1984192 ChemDiv2_001707 CC(N1Cc2ccccc2C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N14 compound treatment 0.234 -0.0136 -0.73 -0.7298 -1.0 1452345 ChemDiv2_001708 CC1C=C(C)C2C(C)C1COC2c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N15 compound treatment 0.241 -0.00658 -0.35 -0.3536 -1.0 1984193 ChemDiv2_001709 CNC(=O)CC1SC(=N)NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N16 compound treatment 0.378 0.13 7.01 7.0085 1.0 1789000 ChemDiv2_001710 Oc1ccc(cc1CC=C)C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N17 compound treatment 0.59 0.342 18.4 18.4009 1.0 1984194 ChemDiv2_001711 Oc1cc(=O)[nH]c2c(C#N)c(Nc3ccc(F)cc3)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N18 compound treatment 0.39 0.142 7.65 7.6533 1.0 1984195 ChemDiv2_001712 CC(C)CNC(=O)c1cc(c(Cl)cc1N2CCCC2)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N19 compound treatment 0.264 0.0164 0.88 0.8823 1.0 1984196 ChemDiv2_001713 COc1ccc(NC(=O)C2CCOC(C)(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N20 compound treatment 0.543 0.295 15.88 15.8752 1.0 1638580 ChemDiv2_001714 CC(C)OC(=O)c1ccc(NC(=O)c2ccc(Cn3cc(Br)cn3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N21 compound treatment 0.271 0.0234 1.26 1.2585 1.0 1984197 ChemDiv2_001715 CCOC(=O)C1(Oc2c(cccc2OC)C1O)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N22 compound treatment 0.395 0.147 7.92 7.922 1.0 1984198 ChemDiv2_001716 COC(=O)c1ccc(COc2cccc(OC)c2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N23 mock treatment 0.242 -0.00558 -0.3 -0.2999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 N24 mock treatment 0.235 -0.0126 -0.68 -0.6761 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O01 compound treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1367198 ChemDiv2_001717 CCC(=O)OC1=C2C(c3ccccc3)c4c(N=C2c5ccccc15)n(C)c(=O)n(C)c4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O02 compound treatment 0.293 0.0454 2.44 2.4407 1.0 1984199 ChemDiv2_001718 CCOC(=O)Cn1c2SCC3COc4ccccc4C3c2sc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O03 compound treatment 0.264 0.0164 0.88 0.8823 1.0 1928909 ChemDiv2_001719 CCCCn1c(CCCO)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O04 compound treatment 0.272 0.0244 1.31 1.3122 1.0 1506224 ChemDiv2_001720 OCC(CO)(CO)NCC(O)CN1c2ccccc2Sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O05 compound treatment 0.252 0.00442 0.24 0.2375 1.0 1984200 ChemDiv2_001721 CCc1c(O)nc2SCCn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O06 compound treatment 0.471 0.223 12.01 12.0061 1.0 1984201 ChemDiv2_001722 COC(=O)C1=C(N)Oc2cc(ccc2C1c3ccccc3OC)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O07 compound treatment 0.245 -0.00258 -0.14 -0.1387 -1.0 1984202 ChemDiv2_001723 CCOC(=O)c1nc(N)c(=O)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O08 compound treatment 0.242 -0.00558 -0.3 -0.2999 -1.0 1984203 ChemDiv2_001724 O=C(C1CCCN(Cc2ccccc2)C1)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O09 compound treatment 0.244 -0.00358 -0.19 -0.1924 -1.0 1984204 ChemDiv2_001725 Cc1ccccc1C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O10 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1984205 ChemDiv2_001726 CC1CCCC(C1)N2CCC(CC2)N3CCN(CCO)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O11 compound treatment 0.252 0.00442 0.24 0.2375 1.0 1984206 ChemDiv2_001727 CC(CN1CCCC1)OC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O12 compound treatment 0.242 -0.00558 -0.3 -0.2999 -1.0 1984207 ChemDiv2_001728 C1CCC(SC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O13 compound treatment 0.388 0.14 7.55 7.5458 1.0 1984208 ChemDiv2_001729 CCC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(OCC(=O)O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O14 compound treatment 0.332 0.0844 4.54 4.5365 1.0 1307120 ChemDiv2_001730 CNC1(CCCC1)c2nnnn2CCOC(=O)Nc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O15 compound treatment 0.333 0.0854 4.59 4.5903 1.0 1984209 ChemDiv2_001731 Clc1c(cn[nH]c1=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O16 compound treatment 0.279 0.0314 1.69 1.6884 1.0 1626573 ChemDiv2_001732 OC(=O)c1nn(ccc1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O17 compound treatment 0.371 0.123 6.63 6.6323 1.0 1984210 ChemDiv2_001733 Cc1nc2cc(NS(=O)(=O)c3ccccc3F)ccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O18 compound treatment 0.459 0.211 11.36 11.3612 1.0 1984211 ChemDiv2_001734 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)OCCN2C(=O)CCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O19 compound treatment 0.27 0.0224 1.2 1.2048 1.0 1863494 ChemDiv2_001735 Fc1ccc(CNc2ccc3[nH]c(=O)[nH]c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O20 compound treatment 0.282 0.0344 1.85 1.8496 1.0 1984212 ChemDiv2_001736 Cc1cc(Cl)cc(C)c1OCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O21 compound treatment 0.262 0.0144 0.77 0.7749 1.0 1984213 ChemDiv2_001737 CC1=Nc2ccccc2N=C(N)C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O22 compound treatment 0.259 0.0114 0.61 0.6137 1.0 1374836 ChemDiv2_001738 Cn1c2ccccc2c3cc(ccc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O23 mock treatment 0.267 0.0194 1.04 1.0436 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 O24 mock treatment 0.249 0.00142 0.08 0.0763 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P01 compound treatment 0.251 0.00342 0.18 0.1837 1.0 1322272 ChemDiv2_001739 O=C(N(Cc1ccccc1)Cc2ccccc2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P02 compound treatment 0.237 -0.0106 -0.57 -0.5686 -1.0 1984214 ChemDiv2_001740 Cn1c2NC(=O)C(CC(=O)O)c2c(=O)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P03 compound treatment 0.238 -0.00958 -0.51 -0.5148 -1.0 1275968 ChemDiv2_001741 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P04 compound treatment 0.282 0.0344 1.85 1.8496 1.0 1984215 ChemDiv2_001742 COc1ccc(cc1)C(=O)NC2=NC(=O)C(C)S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P05 compound treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1230663 ChemDiv2_001743 CCN1CCC2(CC1)NC(CO)(CO)CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P06 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1984216 ChemDiv2_001744 CN(C)c1ncc2C(=O)CC(Cc2n1)c3ccc(cc3)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P07 compound treatment 0.233 -0.0146 -0.78 -0.7835 -1.0 1984217 ChemDiv2_001745 Cc1nn(C)cc1CNC(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P08 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1984218 ChemDiv2_001746 CN(C1CCCCC1)S(=O)(=O)c2cc(ccc2C)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P09 compound treatment 0.24 -0.00758 -0.41 -0.4074 -1.0 1984219 ChemDiv2_001747 Cc1cccc2C(CC(=O)Oc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P10 compound treatment 0.239 -0.00858 -0.46 -0.4611 -1.0 1984220 ChemDiv2_001748 COc1ccccc1Oc2nnnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P11 compound treatment 0.289 0.0414 2.23 2.2258 1.0 1984221 ChemDiv2_001749 CCc1ccc(cc1)C(=O)COC(=O)c2cnccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P12 compound treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1984222 ChemDiv2_001750 CCCCC(C)n1nc(O)c2c(C)cc(=O)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P13 compound treatment 0.231 -0.0166 -0.89 -0.891 -1.0 1984223 ChemDiv2_001751 CC(Cc1ccccc1)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P14 compound treatment 0.247 -5.81E-4 -0.03 -0.0312 -1.0 1984224 ChemDiv2_001752 CC1(CCC(=O)O1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P15 compound treatment 0.236 -0.0116 -0.62 -0.6223 -1.0 1071667 ChemDiv2_001753 CN1CC2(CN(C)CC(C1)(C2=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P16 compound treatment 0.314 0.0664 3.57 3.5692 1.0 1984225 ChemDiv2_001754 COC(=O)c1ccc(CN(C(=O)C)c2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P17 compound treatment 0.415 0.167 9.0 8.9968 1.0 1402191 ChemDiv2_001755 Oc1cc(=O)[nH]c2nc(Nc3ccc(F)cc3)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P18 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1984226 ChemDiv2_001756 CC(C)(C)c1ccc(CCC(CC(=O)O)CC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P19 compound treatment 0.243 -0.00458 -0.25 -0.2462 -1.0 1984227 ChemDiv2_001757 CC1(C)CC(CCO1)C(=O)NCCC(c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P20 compound treatment 0.302 0.0544 2.92 2.9244 1.0 1724846 ChemDiv2_001758 Brc1cnn(Cc2cccc(c2)C(=O)NCc3ccncc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P21 compound treatment 0.228 -0.0196 -1.05 -1.0522 -1.0 1984228 ChemDiv2_001759 OC(NS(=O)(=O)c1ccccc1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P22 compound treatment 0.332 0.0844 4.54 4.5365 1.0 1984229 ChemDiv2_001760 COC(=O)c1ccc(COc2ccc(C#N)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P23 mock treatment 0.235 -0.0126 -0.68 -0.6761 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1373 P24 mock treatment 0.235 -0.0126 -0.68 -0.6761 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A01 compound treatment 0.314 0.0685 3.68 3.6827 1.0 1547693 ChemDiv2_001761 Fc1ccc(OCc2ccc(o2)C(=O)NCC3CCCO3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A02 compound treatment 0.23 -0.0155 -0.83 -0.8313 -1.0 1984230 ChemDiv2_001762 CC(C)(C)NC(=O)CSc1nnnn1c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A03 compound treatment 0.335 0.0895 4.81 4.8112 1.0 1984231 ChemDiv2_001763 CCn1ccc(n1)C(=O)Oc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A04 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1984232 ChemDiv2_001764 OC(=O)C(CC1COc2ccccc2O1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A05 compound treatment 0.259 0.0135 0.73 0.7271 1.0 1984233 ChemDiv2_001765 Brc1cnn(Cc2ccc(o2)C(=O)n3cccn3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A06 compound treatment 0.237 -0.00847 -0.46 -0.4551 -1.0 1984234 ChemDiv2_001766 Clc1ccc(COc2cccc3cccnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A07 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984235 ChemDiv2_001767 CC(=O)NCCOc1c(C)cc(cc1C)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A08 compound treatment 0.229 -0.0165 -0.88 -0.885 -1.0 1984236 ChemDiv2_001768 Brc1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A09 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1259714 ChemDiv2_001769 OC(C(=O)OCCN1CCN(CC=C)CC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A10 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984237 ChemDiv2_001770 CCOC(=O)CSc1nn(C)c(=S)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A11 compound treatment 0.282 0.0365 1.96 1.9631 1.0 1414441 ChemDiv2_001771 Clc1c(NCC=C)cnn(Cc2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A12 compound treatment 0.465 0.22 11.8 11.7972 1.0 1984238 ChemDiv2_001772 CCCC(=O)c1ccc(N2CCc3ccccc3C2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A13 compound treatment 0.228 -0.0175 -0.94 -0.9387 -1.0 1984239 ChemDiv2_001773 Cc1cc(C)c2c(O)nn(C3CCCCCC3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A14 compound treatment 0.421 0.176 9.43 9.4327 1.0 1212585 ChemDiv2_001774 Oc1ccc2occ(C(=O)c3ccc(F)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A15 compound treatment 0.434 0.189 10.13 10.1313 1.0 1984240 ChemDiv2_001775 Cc1nc2cc(Oc3ccc4[nH]c(C)nc4c3)ccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A16 compound treatment 0.248 0.00253 0.14 0.136 1.0 1984241 ChemDiv2_001776 O=C(C1CC1)c2oc3ccccc3c2n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A17 compound treatment 0.307 0.0615 3.31 3.3066 1.0 1984242 ChemDiv2_001777 CC1=Nc2ccccc2N=C(NC(=O)CSc3nnnn3c4ccccc4)C1c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A18 compound treatment 0.229 -0.0165 -0.88 -0.885 -1.0 1984243 ChemDiv2_001778 Cc1ccc(NC(=O)C2(C3c4ccccc4OC2=O)C3(C)C(=O)c5ccccc5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A19 compound treatment 0.398 0.153 8.2 8.1967 1.0 1984244 ChemDiv2_001779 CN(CCO)S(=O)(=O)c1ccc2c(c1)oc(=O)c3cc(ccc32)S(=O)(=O)N(C)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A20 compound treatment 0.433 0.188 10.08 10.0775 1.0 1984245 ChemDiv2_001780 CN(CCCc1nc2ccccc2[nH]1)S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A21 compound treatment 0.246 5.31E-4 0.03 0.0285 1.0 1984246 ChemDiv2_001781 CCc1ccc2nc3nc(C)cc(C)c3c(N)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A22 compound treatment 0.236 -0.00947 -0.51 -0.5088 -1.0 1984247 ChemDiv2_001782 COC(=O)C(C)Sc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A23 mock treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 A24 mock treatment 0.256 0.0105 0.57 0.5659 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B01 compound treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1165883 ChemDiv2_001783 Cc1c(CCCN)c2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B02 compound treatment 0.282 0.0365 1.96 1.9631 1.0 1984248 ChemDiv2_001784 Clc1cccc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B03 compound treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1984249 ChemDiv2_001785 COc1ccc(OC)c(c1)c2sccc2CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B04 compound treatment 0.237 -0.00847 -0.46 -0.4551 -1.0 1114285 ChemDiv2_001786 CCOC(C(=O)O)(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B05 compound treatment 0.234 -0.0115 -0.62 -0.6163 -1.0 1984250 ChemDiv2_001787 CC(CN1CCC(C)CC1)OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B06 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1701764 ChemDiv2_001788 CN(CCc1ccccn1)Cc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B07 compound treatment 0.234 -0.0115 -0.62 -0.6163 -1.0 1984251 ChemDiv2_001789 O=c1n(Cc2ccccn2)n(Cc3ccccn3)c(=O)n1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B08 compound treatment 0.23 -0.0155 -0.83 -0.8313 -1.0 1984252 ChemDiv2_001790 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCOC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B09 compound treatment 0.271 0.0255 1.37 1.372 1.0 1418419 ChemDiv2_001791 COc1nc2CCCNC(=O)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B10 compound treatment 0.276 0.0305 1.64 1.6407 1.0 1984253 ChemDiv2_001792 Cc1oc(cc1C(=O)NCC(=O)O)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B11 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984254 ChemDiv2_001793 COc1c(F)c(F)c(C(=O)O)c(Nc2ccccc2)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B12 compound treatment 0.229 -0.0165 -0.88 -0.885 -1.0 1984255 ChemDiv2_001794 CN(C)CCNC(=O)C1CCCNC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B13 compound treatment 0.476 0.231 12.39 12.3883 1.0 1984256 ChemDiv2_001795 Oc1ccccc1CNc2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B14 compound treatment 0.231 -0.0145 -0.78 -0.7775 -1.0 1984257 ChemDiv2_001796 OCCn1c(CCCCc2nc3ccccc3n2CCO)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B15 compound treatment 0.478 0.233 12.5 12.4957 1.0 1352808 ChemDiv2_001797 COc1ccc(cc1)c2ccc3c(n2)sc4c(O)cc(=O)[nH]c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B16 compound treatment 0.339 0.0935 5.03 5.0262 1.0 1984258 ChemDiv2_001798 CN(C)c1ccc(CNc2ccc(CNc3ncn[nH]3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B17 compound treatment 0.315 0.0695 3.74 3.7365 1.0 1984259 ChemDiv2_001799 CC1=Nc2ccccc2N=C(NC(=O)c3ccccc3)C1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B18 compound treatment 0.538 0.293 15.72 15.72 1.0 1984260 ChemDiv2_001800 CC(C)CCNC(=O)c1ccc-2c(c1)C(=O)c3ccccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B19 compound treatment 0.234 -0.0115 -0.62 -0.6163 -1.0 1984261 ChemDiv2_001801 CN(C)CC(CN(C)C)Oc1cc(C)c2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B20 compound treatment 0.285 0.0395 2.12 2.1243 1.0 1984262 ChemDiv2_001802 CC(=O)Oc1cc2c(C(=O)NCCN3CCOCC3)c(C)oc2c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B21 compound treatment 0.238 -0.00747 -0.4 -0.4014 -1.0 1984263 ChemDiv2_001803 OCc1cn(CC(=O)Nc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B22 compound treatment 0.281 0.0355 1.91 1.9094 1.0 1262792 ChemDiv2_001804 Cc1nonc1NC(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B23 mock treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 B24 mock treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C01 compound treatment 0.35 0.105 5.62 5.6173 1.0 1538682 ChemDiv2_001805 Brc1ccccc1OCc2cccc(c2)C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C02 compound treatment 0.398 0.153 8.2 8.1967 1.0 1984264 ChemDiv2_001806 C(NCc1cccnc1)c2ccc(OCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C03 compound treatment 0.425 0.18 9.65 9.6476 1.0 1984265 ChemDiv2_001807 COc1ccc(CNC(=O)c2ccc(Cn3cc(Cl)cn3)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C04 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984266 ChemDiv2_001808 OC(=O)C(CC(=O)c1ccccc1)c2cn(CCC#N)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C05 compound treatment 0.474 0.229 12.28 12.2808 1.0 1984267 ChemDiv2_001809 CN(C)C(=O)c1ccc(COc2ccccc2Br)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C06 compound treatment 0.541 0.296 15.88 15.8812 1.0 1984268 ChemDiv2_001810 Cc1ccc(cc1)C(=O)COc2cccc(c2)c3cnc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C07 compound treatment 0.229 -0.0165 -0.88 -0.885 -1.0 1123872 ChemDiv2_001811 COc1ccc(C)cc1C(=O)C2CC(C(=O)O)C(C)(C)C2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C08 compound treatment 0.255 0.00953 0.51 0.5122 1.0 1984269 ChemDiv2_001812 Fc1c(F)c(F)c(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C09 compound treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1349824 ChemDiv2_001813 C1COC(CN1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C10 compound treatment 0.484 0.239 12.82 12.8182 1.0 1788844 ChemDiv2_001814 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCCCC2)c3nc4ncccn4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C11 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984270 ChemDiv2_001815 CC(C(=O)O)n1cnc2scc(c3ccc(Br)cc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C12 compound treatment 0.358 0.113 6.05 6.0472 1.0 1984271 ChemDiv2_001816 CCCC(=O)c1ccc(N2CCN(CC)CC2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C13 compound treatment 0.328 0.0825 4.44 4.4351 1.0 1984272 ChemDiv2_001817 CC1=NOC(=O)C1C(c2c(C)nn(c2O)c3ccccc3)c4cccc(Br)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C14 compound treatment 0.256 0.0105 0.57 0.5659 1.0 1553754 ChemDiv2_001818 Cc1ccc(cc1)S(=O)(=O)CCN2CCC(O)(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C15 compound treatment 0.5 0.255 13.68 13.678 1.0 1984273 ChemDiv2_001819 CCc1nc2cc(Oc3ccc4[nH]c(CC)nc4c3)ccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C16 compound treatment 0.231 -0.0145 -0.78 -0.7775 -1.0 1984274 ChemDiv2_001820 COc1ccc2nc(C)c(cc2c1)C(=O)OCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C17 compound treatment 0.294 0.0485 2.61 2.608 1.0 1984275 ChemDiv2_001821 N#Cc1cnc(Nc2nc3ccccc3s2)nc1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C18 compound treatment 0.259 0.0135 0.73 0.7271 1.0 1984276 ChemDiv2_001822 CC1(C2c3cc(Br)ccc3OC(=O)C21C(=O)NCc4ccccc4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C19 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984277 ChemDiv2_001823 Cc1ccnc(NCc2ccc(Cl)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C20 compound treatment 0.521 0.276 14.81 14.8065 1.0 1984278 ChemDiv2_001824 Fc1ccc(cc1)C(=O)Nc2nsc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C21 compound treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1984279 ChemDiv2_001825 CCCc1nc2ccccc2n3cc4c(=O)n(C)c(=O)n(C)c4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C22 compound treatment 0.271 0.0255 1.37 1.372 1.0 1386494 ChemDiv2_001826 CCOc1nc2ccccc2c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C23 mock treatment 0.255 0.00953 0.51 0.5122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 C24 mock treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D01 compound treatment 0.236 -0.00947 -0.51 -0.5088 -1.0 1308879 ChemDiv2_001827 Cc1nn(Cc2ccccc2)c(C)c1C(=O)NS(=O)(=O)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D02 compound treatment 0.271 0.0255 1.37 1.372 1.0 1984280 ChemDiv2_001828 COc1cccc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D03 compound treatment 0.444 0.199 10.67 10.6687 1.0 1984281 ChemDiv2_001829 COc1ccc(cc1)C(=O)c2cc(CC(=O)O)c(s2)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D04 compound treatment 0.25 0.00453 0.24 0.2435 1.0 1984282 ChemDiv2_001830 CC[C@]1(C=CCN2CCC3(C4N(C)c5cc(OC)c(Br)cc53)C21)[C@@H](OC(=O)C)[C@]4(O)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D05 compound treatment 0.232 -0.0135 -0.72 -0.7238 -1.0 1984283 ChemDiv2_001831 CC(CN1CCC(C)CC1)OC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D06 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984284 ChemDiv2_001832 CN(CCc1ccccn1)S(=O)(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D07 compound treatment 0.354 0.109 5.83 5.8322 1.0 1984285 ChemDiv2_001833 Brc1cccc(COC(=O)CN2CC(CC2=O)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D08 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1984286 ChemDiv2_001834 CCCc1nc2c3cc4COC(C)(C)Cc4nc3sc2c(=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D09 compound treatment 0.23 -0.0155 -0.83 -0.8313 -1.0 1984287 ChemDiv2_001835 CC(=CCC1(CN2CC3CN(C1)CC2)C3=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D10 compound treatment 0.418 0.173 9.27 9.2715 1.0 1984288 ChemDiv2_001836 Cc1cccc(OCCn2c(=O)sc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D11 compound treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1984289 ChemDiv2_001837 COC(=O)Cn1ncc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D12 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1222932 ChemDiv2_001838 CC(Cc1cn(Cc2ccccc2)c3ccccc13)NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D13 compound treatment 0.385 0.14 7.5 7.4981 1.0 1984290 ChemDiv2_001839 Oc1ccc(c2n[nH]cc2c3ccc(Cl)cc3)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D14 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1984291 ChemDiv2_001840 Nc1ncn(Cc2ccccc2)c3nc(SCC(=O)O)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D15 compound treatment 0.274 0.0285 1.53 1.5332 1.0 1984292 ChemDiv2_001841 CN1CCc2nc(SCc3cccnc3)c(C#N)cc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D16 compound treatment 0.272 0.0265 1.43 1.4257 1.0 1984293 ChemDiv2_001842 COc1ccccc1CNc2ccc(CNc3ncn[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D17 compound treatment 0.452 0.207 11.1 11.0986 1.0 1984294 ChemDiv2_001843 CC(N1C(=O)c2ccccc2C1=O)C(=O)NC3=Nc4ccccc4N=C(C)C3c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D18 compound treatment 0.541 0.296 15.88 15.8812 1.0 1984295 ChemDiv2_001844 CC(C)(CO)NC(=O)c1ccc-2c(c1)C(=O)c3ccccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D19 compound treatment 0.267 0.0215 1.16 1.157 1.0 1984296 ChemDiv2_001845 CC(C)(Cc1nc2ccccc2[nH]1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D20 compound treatment 0.257 0.0115 0.62 0.6197 1.0 1984297 ChemDiv2_001846 COc1ccc(cc1)C(Nc2ccccn2)c3oc(CO)cc(=O)c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D21 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984298 ChemDiv2_001847 Cc1c(C#N)c(=O)n(nc1C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D22 compound treatment 0.261 0.0155 0.83 0.8346 1.0 1984299 ChemDiv2_001848 NC(=O)[C@@H]1[C@@H](c2ccccc2)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D23 mock treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 D24 mock treatment 0.237 -0.00847 -0.46 -0.4551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E01 compound treatment 0.282 0.0365 1.96 1.9631 1.0 1320012 ChemDiv2_001849 Cc1ccc(CNC(=O)c2cccc(Cn3cc(Cl)cn3)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E02 compound treatment 0.297 0.0515 2.77 2.7692 1.0 1984300 ChemDiv2_001850 COc1cccc(CNCc2cccnc2)c1OCc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E03 compound treatment 0.428 0.183 9.81 9.8088 1.0 1651527 ChemDiv2_001851 Clc1cnn(Cc2ccc(cc2)C(=O)NCc3ccc4OCOc4c3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E04 compound treatment 0.284 0.0385 2.07 2.0706 1.0 1984301 ChemDiv2_001852 CC(=C)Cc1c(C)nc(CC=C)nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E05 compound treatment 0.254 0.00853 0.46 0.4585 1.0 1984302 ChemDiv2_001853 COc1ccc(cc1)S(=O)(=O)N2CCCCC2c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E06 compound treatment 0.504 0.259 13.89 13.8929 1.0 1984303 ChemDiv2_001854 Cc1ccc(cc1)C(=O)COc2ccc(cc2)c3cnc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E07 compound treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1984304 ChemDiv2_001855 COC1(OC)N=C(N)C2(C#N)C(c3ccccc3)C21C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E08 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984305 ChemDiv2_001856 Nc1cccc(CCC(=O)O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E09 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984306 ChemDiv2_001857 O=C1CC(CN1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E10 compound treatment 0.509 0.264 14.16 14.1616 1.0 1788846 ChemDiv2_001858 COc1ccccc1NS(=O)(=O)c2ccc(NC(=O)c3nc4ncccn4n3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E11 compound treatment 0.238 -0.00747 -0.4 -0.4014 -1.0 1984307 ChemDiv2_001859 CNCCn1ccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E12 compound treatment 0.345 0.0995 5.35 5.3486 1.0 1984308 ChemDiv2_001860 CCCCn1c(=O)oc2ccc(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E13 compound treatment 0.251 0.00553 0.3 0.2972 1.0 1594375 ChemDiv2_001861 Clc1ccc(cc1)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E14 compound treatment 0.246 5.31E-4 0.03 0.0285 1.0 1154456 ChemDiv2_001862 CC1CN(CCO)Cc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E15 compound treatment 0.526 0.281 15.08 15.0752 1.0 1984309 ChemDiv2_001863 Cc1ccc(cc1)S(=O)(=O)Nc2ccc3nc([nH]c3c2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E16 compound treatment 0.234 -0.0115 -0.62 -0.6163 -1.0 1274375 ChemDiv2_001864 O=C(c1cccnc1)n2nc3-c4ccccc4C(=O)c5cccc2c35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E17 compound treatment 0.481 0.236 12.66 12.657 1.0 1984310 ChemDiv2_001865 N#Cc1cnc(Nc2nc3ccccc3o2)nc1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E18 compound treatment 0.35 0.105 5.62 5.6173 1.0 1984311 ChemDiv2_001866 CC1(C2c3cc(Br)ccc3OC(=O)C21C(=O)N4CCOCC4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E19 compound treatment 0.293 0.0475 2.55 2.5542 1.0 1984312 ChemDiv2_001867 CN(C)c1ccc(CNc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E20 compound treatment 0.414 0.169 9.06 9.0565 1.0 1984313 ChemDiv2_001868 CC(C)(C)C(=O)Nc1nsc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E21 compound treatment 0.403 0.158 8.47 8.4654 1.0 1984314 ChemDiv2_001869 Cc1ccc(cc1)c2nc3ccccc3n4cc5c(=O)n(C)c(=O)n(C)c5c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E22 compound treatment 0.248 0.00253 0.14 0.136 1.0 1984315 ChemDiv2_001870 CC1(CN(CC2(C)CN(C1)S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E23 mock treatment 0.263 0.0175 0.94 0.9421 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 E24 mock treatment 0.249 0.00353 0.19 0.1898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F01 compound treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1916040 ChemDiv2_001871 CCOC(=O)c1c(C)nc(nc1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F02 compound treatment 0.295 0.0495 2.66 2.6617 1.0 1532847 ChemDiv2_001872 O=C1NC(=O)C2C1Sc3[nH]c(=O)sc3C2c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F03 compound treatment 0.274 0.0285 1.53 1.5332 1.0 1984316 ChemDiv2_001873 COc1ccc(cc1)c2c(oc3ncnc(C)c23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F04 compound treatment 0.279 0.0335 1.8 1.8019 1.0 1137506 ChemDiv2_001874 CC1(C)Oc2ccc3ccc(=O)oc3c2C(C1O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F05 compound treatment 0.292 0.0465 2.5 2.5005 1.0 1984317 ChemDiv2_001875 CC(CN1CCC(C)CC1)OC(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F06 compound treatment 0.556 0.311 16.69 16.6873 1.0 1984318 ChemDiv2_001876 CCCSc1nnc2nc3n(C)c4ccccc4c3nn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F07 compound treatment 0.549 0.304 16.31 16.3111 1.0 1984319 ChemDiv2_001877 COC(=O)c1ccc(cc1)n2nnnc2SCC(=O)c3ccc(O)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F08 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984320 ChemDiv2_001878 Oc1nc2ccccc2nc1CCC(=O)OCc3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F09 compound treatment 0.245 -4.69E-4 -0.03 -0.0252 -1.0 1984321 ChemDiv2_001879 CC(=CCC1(CN2CC3CN(C1)CC2)C3O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F10 compound treatment 0.41 0.165 8.84 8.8416 1.0 1984322 ChemDiv2_001880 Cc1ccc(OCCn2c(=O)sc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F11 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984323 ChemDiv2_001881 COC(=O)C(C)n1ncc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F12 compound treatment 0.292 0.0465 2.5 2.5005 1.0 1984324 ChemDiv2_001882 CC(N)Cc1c[nH]c2cc3OCCOc3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F13 compound treatment 0.346 0.101 5.4 5.4023 1.0 1984325 ChemDiv2_001883 CCCc1cc(c2n[nH]cc2c3ccc4OCCCOc4c3)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F14 compound treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1984326 ChemDiv2_001884 CCN(CC)Cc1cc(oc1CC)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F15 compound treatment 0.303 0.0575 3.09 3.0916 1.0 1984327 ChemDiv2_001885 COc1csc2nc(C)cc(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F16 compound treatment 0.293 0.0475 2.55 2.5542 1.0 1984328 ChemDiv2_001886 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Sc3nc[nH]n3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F17 compound treatment 0.29 0.0445 2.39 2.393 1.0 1984329 ChemDiv2_001887 CCOC(=O)CC1=Nc2ccccc2NC(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F18 compound treatment 0.528 0.283 15.18 15.1826 1.0 1984330 ChemDiv2_001888 O=C(NCc1ccco1)c2ccc-3c(c2)C(=O)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F19 compound treatment 0.487 0.242 12.98 12.9794 1.0 1984331 ChemDiv2_001889 Cc1ccc2[nH]c(CCc3nc4cc(C)ccc4[nH]3)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F20 compound treatment 0.301 0.0555 2.98 2.9841 1.0 1163426 ChemDiv2_001890 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCc3cccc(O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F21 compound treatment 0.289 0.0435 2.34 2.3393 1.0 1984332 ChemDiv2_001891 CCOC(=O)c1nn(c2ccc(C)cc2)c(=O)c3c(N)scc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F22 compound treatment 0.257 0.0115 0.62 0.6197 1.0 1984333 ChemDiv2_001892 COC(=O)Nc1ccc(Cl)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F23 mock treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 F24 mock treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G01 compound treatment 0.252 0.00653 0.35 0.351 1.0 1880807 ChemDiv2_001893 CC(C)CNC(=O)c1cccc(Cn2cc(Cl)cn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G02 compound treatment 0.409 0.164 8.79 8.7878 1.0 1984334 ChemDiv2_001894 CCOc1cc(CNCc2cccnc2)cc(Cl)c1OCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G03 compound treatment 0.396 0.151 8.09 8.0892 1.0 1984335 ChemDiv2_001895 Clc1cnn(Cc2ccc(cc2)C(=O)NCc3ccccc3Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G04 compound treatment 0.428 0.183 9.81 9.8088 1.0 1984336 ChemDiv2_001896 OC(=O)COc1ccc(cc1)S(=O)(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G05 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1984337 ChemDiv2_001897 CCC1CC(C)(C)CCN1C(=O)c2cc(=O)[nH]c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G06 compound treatment 0.312 0.0665 3.58 3.5753 1.0 1224585 ChemDiv2_001898 Cc1nc2ccccc2nc1OCC(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G07 compound treatment 0.256 0.0105 0.57 0.5659 1.0 1984338 ChemDiv2_001899 CCOC1(OCC)N=C(N)C2(C#N)C(c3ccc(NC(=O)C)cc3)C21C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G08 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984339 ChemDiv2_001900 CCCN1C(=O)C(NC(=O)C)c2cc(F)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G09 compound treatment 0.237 -0.00847 -0.46 -0.4551 -1.0 1984340 ChemDiv2_001901 CC(C)N1CCC(C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G10 compound treatment 0.401 0.156 8.36 8.3579 1.0 1788848 ChemDiv2_001902 Cc1cc(C)c(NS(=O)(=O)c2ccc(NC(=O)c3nc4ncccn4n3)cc2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G11 compound treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1136118 ChemDiv2_001903 C(NCC1CCCO1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G12 compound treatment 0.251 0.00553 0.3 0.2972 1.0 1446362 ChemDiv2_001904 CC(=O)Nc1scc(c1C(=O)N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G13 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984341 ChemDiv2_001905 Clc1ccccc1OCCCN2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G14 compound treatment 0.238 -0.00747 -0.4 -0.4014 -1.0 1483195 ChemDiv2_001906 CCOC(=O)c1oc2ccccc2c1CN3CCN(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G15 compound treatment 0.251 0.00553 0.3 0.2972 1.0 1984342 ChemDiv2_001907 C(/C=C/c1ccccc1)N2CCN(C/C=C/c3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G16 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1933627 ChemDiv2_001908 COC(=O)c1nc2nc(C)cc(C)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G17 compound treatment 0.334 0.0885 4.76 4.7575 1.0 1984343 ChemDiv2_001909 COC(=O)CSc1nc(C)c2CCCCc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G18 compound treatment 0.255 0.00953 0.51 0.5122 1.0 1984344 ChemDiv2_001910 OC1(C(OC(=O)C21CCCC2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G19 compound treatment 0.284 0.0385 2.07 2.0706 1.0 1984345 ChemDiv2_001911 CCN(CC)c1ccc(CNc2ccc(Br)cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G20 compound treatment 0.432 0.187 10.02 10.0238 1.0 1984346 ChemDiv2_001912 COc1cc(cc(OC)c1OC)C(=O)Nc2nsc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G21 compound treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1984347 ChemDiv2_001913 Cc1ccc(cc1)c2c3c(=O)n(C)c(=O)n(C)c3c4c(C)cc(C)nn24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G22 compound treatment 0.273 0.0275 1.48 1.4795 1.0 1984348 ChemDiv2_001914 O=c1oc2cc(ccc2c3ccc(cc13)S(=O)(=O)N4CCCC4)S(=O)(=O)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G23 mock treatment 0.246 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 G24 mock treatment 0.236 -0.00947 -0.51 -0.5088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H01 compound treatment 0.263 0.0175 0.94 0.9421 1.0 1452174 ChemDiv2_001915 CSc1nc(nc2[nH]c(cc(=O)c12)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H02 compound treatment 0.316 0.0705 3.79 3.7902 1.0 1984349 ChemDiv2_001916 Cc1nc(SCc2ccc(cc2)C(=O)O)nc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H03 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1984350 ChemDiv2_001917 CC(CN(C)Cc1ccccc1)OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H04 compound treatment 0.237 -0.00847 -0.46 -0.4551 -1.0 1984351 ChemDiv2_001918 COc1cc2CCN(C3CC4(C=CC(=O)C=C4)c(c32)c1OC)C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H05 compound treatment 0.265 0.0195 1.05 1.0496 1.0 1984352 ChemDiv2_001919 CC(CN1CCN(Cc2ccccc2)CC1)OC(=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H06 compound treatment 0.257 0.0115 0.62 0.6197 1.0 1984353 ChemDiv2_001920 CC(=O)Nc1ccccc1c2nn3c(C)csc3nc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H07 compound treatment 0.251 0.00553 0.3 0.2972 1.0 1984354 ChemDiv2_001921 Fc1ccc(NC(=O)CS(=O)(=O)c2nnnn2C3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H08 compound treatment 0.432 0.187 10.02 10.0238 1.0 1984355 ChemDiv2_001922 CCOC(=O)c1ccc(COC(=O)CCc2nc3ccccc3nc2O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H09 compound treatment 0.252 0.00653 0.35 0.351 1.0 1984356 ChemDiv2_001923 Cc1ccc(CC2(CN3CC4CN(C2)CC3)C4=O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H10 compound treatment 0.329 0.0835 4.49 4.4888 1.0 1984357 ChemDiv2_001924 COc1ccccc1OCCn2c(=O)sc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H11 compound treatment 0.274 0.0285 1.53 1.5332 1.0 1984358 ChemDiv2_001925 CC1CCC(=O)C(C1)C(CC(=O)c2ccccc2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H12 compound treatment 0.285 0.0395 2.12 2.1243 1.0 1984359 ChemDiv2_001926 Cc1cc(C)c2cc3n(ccc3cc2n1)C4OC[C@H](O)[C@H](O)[C@H]4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H13 compound treatment 0.305 0.0595 3.2 3.1991 1.0 1984360 ChemDiv2_001927 Cn1c(nc2cc(N)ccc12)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H14 compound treatment 0.515 0.27 14.48 14.484 1.0 1984361 ChemDiv2_001928 Cc1ccc(Nc2nc(=O)c3cccnc3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H15 compound treatment 0.513 0.268 14.38 14.3766 1.0 1984362 ChemDiv2_001929 CNc1nc2[nH]c(=O)c3C(C(=C(N)Oc3c2s1)C#N)c4cccc(F)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H16 compound treatment 0.288 0.0425 2.29 2.2855 1.0 1984363 ChemDiv2_001930 Cc1ccc(cc1)S(=O)(=O)/N=C\2/C=C(Sc3nc[nH]n3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H17 compound treatment 0.364 0.119 6.37 6.3696 1.0 1984364 ChemDiv2_001931 Cc1ccc(Nc2nc(CSc3nnnn3c4ccccc4)cc(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H18 compound treatment 0.256 0.0105 0.57 0.5659 1.0 1984365 ChemDiv2_001932 CC1=CC(=O)N(C1c2ccc(Cl)cc2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H19 compound treatment 0.536 0.291 15.61 15.6125 1.0 1984366 ChemDiv2_001933 CC(C)OC(=O)CCCN1C(=O)c2ccc(N)cc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H20 compound treatment 0.283 0.0375 2.02 2.0169 1.0 1984367 ChemDiv2_001934 Cc1ccc2oc(=O)cc(CSc3cnc4ccccc4n3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H21 compound treatment 0.256 0.0105 0.57 0.5659 1.0 1984368 ChemDiv2_001935 OCc1ccc(cc1F)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H22 compound treatment 0.246 5.31E-4 0.03 0.0285 1.0 1519166 ChemDiv2_001936 OCCN1CCN(CCSc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H23 mock treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 H24 mock treatment 0.241 -0.00447 -0.24 -0.2401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I01 compound treatment 0.266 0.0205 1.1 1.1033 1.0 1518251 ChemDiv2_001937 CCc1c(C)sc(NC(=O)c2ccc(Cn3nc(C)c(Cl)c3C)o2)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I02 compound treatment 0.238 -0.00747 -0.4 -0.4014 -1.0 1984369 ChemDiv2_001938 CC(C)(CO)NCc1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I03 compound treatment 0.34 0.0945 5.08 5.0799 1.0 1984370 ChemDiv2_001939 CCN(CC)C(=O)c1ccc(Cn2cc(Cl)cn2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I04 compound treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1984371 ChemDiv2_001940 COc1cc(CO)cc(Br)c1OCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I05 compound treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1984372 ChemDiv2_001941 Clc1ncnc2n(c3ccccc3)c(=S)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I06 compound treatment 0.536 0.291 15.61 15.6125 1.0 1984373 ChemDiv2_001942 Cc1ccc2cccc(OCC(=O)c3ccc(C)c(C)c3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I07 compound treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1984374 ChemDiv2_001943 COc1ccc(cc1OC)C2C3(C#N)C(=NC4(OCCO4)C23C#N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I08 compound treatment 0.54 0.295 15.83 15.8275 1.0 1984375 ChemDiv2_001944 OC(=O)COc1ccc(cc1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I09 compound treatment 0.261 0.0155 0.83 0.8346 1.0 1670408 ChemDiv2_001945 CN(C)CCOC(=O)c1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I10 compound treatment 0.37 0.125 6.69 6.692 1.0 1984376 ChemDiv2_001946 CC(C)CC(NC(=O)c1ccco1)C(=O)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I11 compound treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1027543 ChemDiv2_001947 NCc1cc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I12 compound treatment 0.324 0.0785 4.22 4.2201 1.0 1984377 ChemDiv2_001948 CCCCc1cc(c2n[nH]c(=S)o2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I13 compound treatment 0.536 0.291 15.61 15.6125 1.0 1984378 ChemDiv2_001949 Oc1ccc(cc1)N(Cc2ccco2)C(=O)COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I14 compound treatment 0.438 0.193 10.35 10.3462 1.0 1294440 ChemDiv2_001950 CCc1nc2c3ccccc3oc2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I15 compound treatment 0.315 0.0695 3.74 3.7365 1.0 1984379 ChemDiv2_001951 CC(Oc1cccc(Cl)c1)C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I16 compound treatment 0.254 0.00853 0.46 0.4585 1.0 1984380 ChemDiv2_001952 Cc1cc(C)n2nc(nc2n1)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I17 compound treatment 0.258 0.0125 0.67 0.6734 1.0 1984381 ChemDiv2_001953 O=c1[nH]c2ccccc2c(N3CCOCC3)c1N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I18 compound treatment 0.484 0.239 12.82 12.8182 1.0 1984382 ChemDiv2_001954 CCOc1cccc(=O)c2c(C)n(CC(=O)c3ccccc3)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I19 compound treatment 0.22 -0.0255 -1.37 -1.3686 -1.0 1984383 ChemDiv2_001955 Oc1ccccc1CNc2ccccc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I20 compound treatment 0.548 0.303 16.26 16.2574 1.0 1984384 ChemDiv2_001956 O=C(Nc1nsc(n1)c2ccccc2)c3ccc4ncsc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I21 compound treatment 0.308 0.0625 3.36 3.3603 1.0 1984385 ChemDiv2_001957 CC(C)(C)C(=O)N1CCn2c1nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I22 compound treatment 0.394 0.149 7.98 7.9818 1.0 1336280 ChemDiv2_001958 C=CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I23 mock treatment 0.25 0.00453 0.24 0.2435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 I24 mock treatment 0.251 0.00553 0.3 0.2972 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J01 compound treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1872139 ChemDiv2_001959 CC(C)c1cc(=O)c2c(C)nc(nc2[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J02 compound treatment 0.254 0.00853 0.46 0.4585 1.0 1984386 ChemDiv2_001960 CN(CCc1ccccn1)Cc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J03 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984387 ChemDiv2_001961 CC(CN(C)Cc1ccccc1)OC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J04 compound treatment 0.309 0.0635 3.41 3.414 1.0 1984388 ChemDiv2_001962 CC1(C)Oc2ccc3ccc(=O)oc3c2C(=C1Cl)/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J05 compound treatment 0.272 0.0265 1.43 1.4257 1.0 1984389 ChemDiv2_001963 CC(CN1CCN(Cc2ccccc2)CC1)OC(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J06 compound treatment 0.262 0.0165 0.89 0.8884 1.0 1984390 ChemDiv2_001964 COC(=O)C1=C(C)n2nnnc2NC1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J07 compound treatment 0.294 0.0485 2.61 2.608 1.0 1984391 ChemDiv2_001965 CCc1nnc2Sc3nc4ccccc4nc3Nn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J08 compound treatment 0.379 0.134 7.18 7.1757 1.0 1984392 ChemDiv2_001966 Oc1nc2ccccc2nc1CCC(=O)OCc3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J09 compound treatment 0.232 -0.0135 -0.72 -0.7238 -1.0 1984393 ChemDiv2_001967 Cc1ccc(CC2(CN3CC4CN(C2)CC3)C4O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J10 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984394 ChemDiv2_001968 Cc1ccccc1OC2C(N(CC3CCCO3)C2=O)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J11 compound treatment 0.236 -0.00947 -0.51 -0.5088 -1.0 1984395 ChemDiv2_001969 COc1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J12 compound treatment 0.258 0.0125 0.67 0.6734 1.0 1984396 ChemDiv2_001970 Cc1cc(C)c2cc3N(CC(O)CO)CCc3cc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J13 compound treatment 0.251 0.00553 0.3 0.2972 1.0 1984397 ChemDiv2_001971 Cn1cnc2nc(SCC(=O)O)nc(N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J14 compound treatment 0.462 0.217 11.64 11.6359 1.0 1984398 ChemDiv2_001972 COC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J15 compound treatment 0.263 0.0175 0.94 0.9421 1.0 1984399 ChemDiv2_001973 CN(C)S(=O)(=O)n1nc(C)nc1c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J16 compound treatment 0.262 0.0165 0.89 0.8884 1.0 1984400 ChemDiv2_001974 Clc1ccc(cc1)S(=O)(=O)/N=C\2/C=C(Sc3nc[nH]n3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J17 compound treatment 0.276 0.0305 1.64 1.6407 1.0 1984401 ChemDiv2_001975 CCOc1ccc(Nc2nc(CC(=O)OC)cc(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J18 compound treatment 0.591 0.346 18.57 18.5681 1.0 1024984 ChemDiv2_001976 COc1cc2cccc(OC)c(=O)c2c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J19 compound treatment 0.246 5.31E-4 0.03 0.0285 1.0 1984402 ChemDiv2_001977 CC(=O)n1nc(nc1NCc2ccco2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J20 compound treatment 0.287 0.0415 2.23 2.2318 1.0 1945041 ChemDiv2_001978 CC(NC(=O)CSc1nnc(c2ccco2)n1c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J21 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1984403 ChemDiv2_001979 COc1cc(N2CCCC2)c(OC)cc1CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J22 compound treatment 0.258 0.0125 0.67 0.6734 1.0 1260752 ChemDiv2_001980 COc1ccc(cc1OC)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J23 mock treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 J24 mock treatment 0.246 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K01 compound treatment 0.452 0.207 11.1 11.0986 1.0 1146389 ChemDiv2_001981 O=C(NCc1ccncc1)c2cccc(COc3ccc4CCCc4c3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K02 compound treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1984404 ChemDiv2_001982 CCOc1ccccc1CNC(C)(C)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K03 compound treatment 0.523 0.278 14.91 14.9139 1.0 1514497 ChemDiv2_001983 CC1CCN(CC1)C(=O)c2ccc(COc3ccccc3Cl)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K04 compound treatment 0.452 0.207 11.1 11.0986 1.0 1984405 ChemDiv2_001984 CCOC(=O)COc1ccc(cc1)S(=O)(=O)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K05 compound treatment 0.253 0.00753 0.4 0.4047 1.0 1984406 ChemDiv2_001985 Oc1ncnc2n(c3ccccc3)c(=S)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K06 compound treatment 0.351 0.106 5.67 5.671 1.0 1984407 ChemDiv2_001986 CC(=O)Nc1ccccc1c2nc3ccccc3nc2OCC(=O)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K07 compound treatment 0.532 0.287 15.4 15.3976 1.0 1984408 ChemDiv2_001987 COc1ccc(cc1)c2cc3[nH]c(Cc4ccccc4)cc(=O)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K08 compound treatment 0.306 0.0605 3.25 3.2528 1.0 1984409 ChemDiv2_001988 OC(=O)COc1cccc(c1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K09 compound treatment 0.297 0.0515 2.77 2.7692 1.0 1984410 ChemDiv2_001989 CCC(=O)Nc1nonc1c2nc3ccccc3n2CCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K10 compound treatment 0.262 0.0165 0.89 0.8884 1.0 1224519 ChemDiv2_001990 CCOC(=O)N1CCC(CC1)NC(=O)CNC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K11 compound treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1984411 ChemDiv2_001991 NCc1ccsc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K12 compound treatment 0.246 5.31E-4 0.03 0.0285 1.0 1984412 ChemDiv2_001992 CC(C(CC(=O)O)C(=O)NC1CCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K13 compound treatment 0.336 0.0905 4.86 4.865 1.0 1984413 ChemDiv2_001993 COc1cc(cc(OC)c1OC)C(=O)N(Cc2ccco2)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K14 compound treatment 0.255 0.00953 0.51 0.5122 1.0 1548674 ChemDiv2_001994 COC(=O)c1cc(CN2CCOCC2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K15 compound treatment 0.279 0.0335 1.8 1.8019 1.0 1234356 ChemDiv2_001995 CCC(Oc1ccccc1)C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K16 compound treatment 0.267 0.0215 1.16 1.157 1.0 1984414 ChemDiv2_001996 Cc1ccc(cc1)S(=O)(=O)N2CCCOC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K17 compound treatment 0.267 0.0215 1.16 1.157 1.0 1984415 ChemDiv2_001997 Cc1ccc(cc1)n2c(=O)oc3ccc(Cl)cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K18 compound treatment 0.291 0.0455 2.45 2.4468 1.0 1195345 ChemDiv2_001998 OCCCc1nc2ccccc2n1Cc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K19 compound treatment 0.25 0.00453 0.24 0.2435 1.0 1984416 ChemDiv2_001999 Cc1ccc(NCc2ccccc2O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K20 compound treatment 0.314 0.0685 3.68 3.6827 1.0 1984417 ChemDiv2_002000 Cc1ccc(cc1)C(CCNC(=O)c2cccs2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K21 compound treatment 0.268 0.0225 1.21 1.2108 1.0 1081879 ChemDiv2_002001 CCOC(=O)Cn1c(=O)n(CC(=O)OCC)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K22 compound treatment 0.273 0.0275 1.48 1.4795 1.0 1984418 ChemDiv2_002002 COc1cc2CCN3CC(CC(C)C)/C(=N/O)/CC3c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K23 mock treatment 0.258 0.0125 0.67 0.6734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 K24 mock treatment 0.255 0.00953 0.51 0.5122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L01 compound treatment 0.238 -0.00747 -0.4 -0.4014 -1.0 1239694 ChemDiv2_002003 OC1CC2CCC(C1)N2CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L02 compound treatment 0.336 0.0905 4.86 4.865 1.0 1984419 ChemDiv2_002004 Cc1ccc(cc1)S(=O)(=O)CC2CSc3nc4ccccc4n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L03 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1984420 ChemDiv2_002005 O=C(OCCN1CCCCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L04 compound treatment 0.255 0.00953 0.51 0.5122 1.0 1984421 ChemDiv2_002006 O=C(C1CCCCC1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L05 compound treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1984422 ChemDiv2_002007 OCCC1(CCOC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L06 compound treatment 0.301 0.0555 2.98 2.9841 1.0 1984423 ChemDiv2_002008 Cc1csc(n1)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L07 compound treatment 0.256 0.0105 0.57 0.5659 1.0 1984424 ChemDiv2_002009 CCCc1nnc2Sc3nc4ccccc4nc3Nn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L08 compound treatment 0.258 0.0125 0.67 0.6734 1.0 1984425 ChemDiv2_002010 COc1cc(C)c(cc1C)S(=O)(=O)N2CCN=C2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L09 compound treatment 0.262 0.0165 0.89 0.8884 1.0 1984426 ChemDiv2_002011 NC(=O)Cn1cnc(c1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L10 compound treatment 0.307 0.0615 3.31 3.3066 1.0 1984427 ChemDiv2_002012 Clc1ccc(OC2C(N(CC3CCCO3)C2=O)c4ccc5OCOc5c4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L11 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984428 ChemDiv2_002013 CN1CCN(CCCOc2ccc(Br)cc2C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L12 compound treatment 0.57 0.325 17.44 17.4396 1.0 1984429 ChemDiv2_002014 OC(=O)c1cccc(Nc2nc(cs2)c3cccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L13 compound treatment 0.539 0.294 15.77 15.7738 1.0 1984430 ChemDiv2_002015 COc1ccc(OCC(Cn2cnc3ccccc23)OC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L14 compound treatment 0.439 0.194 10.4 10.4 1.0 1984431 ChemDiv2_002016 O=c1nc(NCc2ccco2)sc3ncccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L15 compound treatment 0.414 0.169 9.06 9.0565 1.0 1984432 ChemDiv2_002017 CC(C)C(=O)Nc1nsc(n1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L16 compound treatment 0.288 0.0425 2.29 2.2855 1.0 1984433 ChemDiv2_002018 OC(=O)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc(=O)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L17 compound treatment 0.275 0.0295 1.59 1.5869 1.0 1984434 ChemDiv2_002019 Fc1ccc(Nc2nc(CSc3nnnn3c4ccccc4)cc(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L18 compound treatment 0.443 0.198 10.61 10.6149 1.0 1984435 ChemDiv2_002020 Cc1ccccc1Nc2cc3ccccc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L19 compound treatment 0.427 0.182 9.76 9.7551 1.0 1984436 ChemDiv2_002021 O=S(=O)(Nc1ccc2n3CCN(Cc4ccccc4)Cc3nc2c1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L20 compound treatment 0.27 0.0245 1.32 1.3183 1.0 1361865 ChemDiv2_002022 Fc1ccc(C(=O)NCC2CCCO2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L21 compound treatment 0.29 0.0445 2.39 2.393 1.0 1984437 ChemDiv2_002023 OCc1ccc(o1)c2cccc(c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L22 compound treatment 0.291 0.0455 2.45 2.4468 1.0 1928704 ChemDiv2_002024 Fc1ccc(OCCNC(=O)c2ccccc2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L23 mock treatment 0.252 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 L24 mock treatment 0.238 -0.00747 -0.4 -0.4014 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M01 compound treatment 0.378 0.133 7.12 7.122 1.0 1255844 ChemDiv2_002025 Cc1cc(C)cc(OCc2ccc(o2)C(=O)NC3CCOC3=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M02 compound treatment 0.294 0.0485 2.61 2.608 1.0 1984438 ChemDiv2_002026 CC(C)(C)NC(=O)COc1ccc(CNc2nc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M03 compound treatment 0.548 0.303 16.26 16.2574 1.0 1984439 ChemDiv2_002027 CCOc1ccc(OCc2ccc(o2)C(=O)OCc3ccccn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M04 compound treatment 0.279 0.0335 1.8 1.8019 1.0 1984440 ChemDiv2_002028 CN1CCN(CC1)c2nc(ncc2F)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M05 compound treatment 0.231 -0.0145 -0.78 -0.7775 -1.0 1022873 ChemDiv2_002029 Nc1ccc(CC(C(=O)O)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M06 compound treatment 0.321 0.0755 4.06 4.0589 1.0 1984441 ChemDiv2_002030 Cc1nc2ccccc2nc1OCc3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M07 compound treatment 0.241 -0.00447 -0.24 -0.2401 -1.0 1984442 ChemDiv2_002031 OC(=O)[C@H]1CCCC[C@H]1C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M08 compound treatment 0.307 0.0615 3.31 3.3066 1.0 1984443 ChemDiv2_002032 Fc1ccc(cc1)c2cc(nc3ncnn23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M09 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1984444 ChemDiv2_002033 CN(C)CC(CN(C)C)OC(=O)c1cc2cc(C)ccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M10 compound treatment 0.288 0.0425 2.29 2.2855 1.0 1984445 ChemDiv2_002034 CN(C)C(=O)Oc1ccc(cc1)c2nnco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M11 compound treatment 0.463 0.218 11.69 11.6897 1.0 1984446 ChemDiv2_002035 OC(CSCC(=O)Nc1ccccc1)Cn2c3ccccc3c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M12 compound treatment 0.268 0.0225 1.21 1.2108 1.0 1984447 ChemDiv2_002036 COc1ccc2oc(C)c(C(=O)Cn3ccnc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M13 compound treatment 0.248 0.00253 0.14 0.136 1.0 1984448 ChemDiv2_002037 OC(=O)CCc1nn2c3ccccc3nc2n(CCN4CCCCC4)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M14 compound treatment 0.431 0.186 9.97 9.9701 1.0 1521505 ChemDiv2_002038 Cc1ccc(NCc2c(C#N)c3ccccc3n2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M15 compound treatment 0.265 0.0195 1.05 1.0496 1.0 1984449 ChemDiv2_002039 CC(O)CNCc1sccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M16 compound treatment 0.285 0.0395 2.12 2.1243 1.0 1984450 ChemDiv2_002040 CC1(C2c3cc(Br)ccc3OC(=O)C21C(=O)c4ccco4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M17 compound treatment 0.479 0.234 12.55 12.5495 1.0 1984451 ChemDiv2_002041 COc1ccc(CCNc2cc(=O)oc3ccccc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M18 compound treatment 0.287 0.0415 2.23 2.2318 1.0 1943397 ChemDiv2_002042 OCCCc1nc2ccccc2n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M19 compound treatment 0.253 0.00753 0.4 0.4047 1.0 1984452 ChemDiv2_002043 Cn1nnn(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M20 compound treatment 0.308 0.0625 3.36 3.3603 1.0 1984453 ChemDiv2_002044 COc1ccccc1C(CCNCc2cccs2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M21 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1125962 ChemDiv2_002045 O=C(Cn1n(CC(=O)N2CCCCC2)c(=O)n(c3ccccc3)c1=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M22 compound treatment 0.263 0.0175 0.94 0.9421 1.0 1352240 ChemDiv2_002046 CCOC(=O)C1CCCN(CCCc2ccccc2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M23 mock treatment 0.249 0.00353 0.19 0.1898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 M24 mock treatment 0.247 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N01 compound treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1427661 ChemDiv2_002047 CN1C2CCC1CC(C2)N(CCc3ccccc3)C(=O)c4cc(C)cc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N02 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1984454 ChemDiv2_002048 CC(C)c1nc2sc3c4ncnn4cnc3c2c5CCCCc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N03 compound treatment 0.267 0.0215 1.16 1.157 1.0 1573913 ChemDiv2_002049 O=C(OCCN1CCCCC1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N04 compound treatment 0.285 0.0395 2.12 2.1243 1.0 1275946 ChemDiv2_002050 OC(C(=O)c1cccs1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N05 compound treatment 0.23 -0.0155 -0.83 -0.8313 -1.0 1984455 ChemDiv2_002051 Cn1nnnc1SCC(=O)NC(C(=O)O)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N06 compound treatment 0.245 -4.69E-4 -0.03 -0.0252 -1.0 1655781 ChemDiv2_002052 O=c1cc(Nc2ccccc2)c3ccccc3o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N07 compound treatment 0.321 0.0755 4.06 4.0589 1.0 1984456 ChemDiv2_002053 CN(Cc1ccccc1)C2CCN(Cc3cc(Br)ccc3O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N08 compound treatment 0.254 0.00853 0.46 0.4585 1.0 1984457 ChemDiv2_002054 CCOc1ccc(cc1)S(=O)(=O)N2CCN=C2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N09 compound treatment 0.265 0.0195 1.05 1.0496 1.0 1445699 ChemDiv2_002055 OC(=O)Cn1cnc(c1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N10 compound treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1984458 ChemDiv2_002056 CSc1n[nH]c(NCc2cccs2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N11 compound treatment 0.425 0.18 9.65 9.6476 1.0 1984459 ChemDiv2_002057 O=c1n(CCOc2ccccc2)ncc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N12 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1984460 ChemDiv2_002058 Cc1cc2nc(cc(N)n2n1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N13 compound treatment 0.26 0.0145 0.78 0.7809 1.0 1984461 ChemDiv2_002059 CC(C)(O)C#Cc1ccc(cc1)C2NCCS2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N14 compound treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1984462 ChemDiv2_002060 O/N=C/C(=O)NCC1CCNCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N15 compound treatment 0.464 0.219 11.74 11.7434 1.0 1984463 ChemDiv2_002061 CCCC1CC(C)(OC1=O)c2csc(Cc3ccc(OCC)cc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N16 compound treatment 0.454 0.209 11.21 11.206 1.0 1984464 ChemDiv2_002062 CN(CCCc1nc2ccccc2[nH]1)S(=O)(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N17 compound treatment 0.29 0.0445 2.39 2.393 1.0 1984465 ChemDiv2_002063 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N18 compound treatment 0.272 0.0265 1.43 1.4257 1.0 1984466 ChemDiv2_002064 CCc1cc(C(N2CCN(CCO)CC2)c3cccc(OC)c3)c(NC(=O)c4ccccc4)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N19 compound treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1984467 ChemDiv2_002065 Cc1nn(C)c(C)c1NS(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N20 compound treatment 0.257 0.0115 0.62 0.6197 1.0 1235308 ChemDiv2_002066 CC(=C1C2CC2C3C(C31)C(=O)O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N21 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1984468 ChemDiv2_002067 COC(=O)C1=NOC2C1C(=O)N(C2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N22 compound treatment 0.289 0.0435 2.34 2.3393 1.0 1038516 ChemDiv2_002068 Clc1ccc(cc1)C(=O)CC2SC(=N)NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N23 mock treatment 0.245 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 N24 mock treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O01 compound treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1984469 ChemDiv2_002069 Cn1ncc(Br)c1C(=O)Oc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O02 compound treatment 0.403 0.158 8.47 8.4654 1.0 1984470 ChemDiv2_002070 COc1cc(CNc2ccc3[nH]c(=O)[nH]c3c2)cc(Cl)c1OCC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O03 compound treatment 0.271 0.0255 1.37 1.372 1.0 1434511 ChemDiv2_002071 COc1ccccc1OCc2ccc(o2)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O04 compound treatment 0.368 0.123 6.58 6.5846 1.0 1984471 ChemDiv2_002072 C1C=CC2C1C(Nc3ccc(cc23)c4ccccc4)c5ccncc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O05 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1334868 ChemDiv2_002073 COc1ccc(cc1OC)C(CC(=O)O)c2ccc(OC)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O06 compound treatment 0.247 0.00153 0.08 0.0823 1.0 1984472 ChemDiv2_002074 CCOC(=O)c1ccc(COc2nc3ccccc3nc2c4ccccc4NC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O07 compound treatment 0.389 0.144 7.71 7.7131 1.0 1984473 ChemDiv2_002075 OC(=O)c1ccc(NC(=O)C2CC(=O)OC2c3ccccc3)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O08 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1874564 ChemDiv2_002076 NC(=O)COc1ccc(=O)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O09 compound treatment 0.264 0.0185 1.0 0.9958 1.0 1984474 ChemDiv2_002077 CCOC(=O)C1=C(NC(=O)CSc2nnnn2c3ccccc3)SC4CN(C)CCC41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O10 compound treatment 0.241 -0.00447 -0.24 -0.2401 -1.0 1984475 ChemDiv2_002078 Cc1ccc(NC(C(=O)N)c2c(C)[nH]c(=O)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O11 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1984476 ChemDiv2_002079 Clc1ccccc1C(=O)NS(=O)(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O12 compound treatment 0.251 0.00553 0.3 0.2972 1.0 1984477 ChemDiv2_002080 Oc1ccc(Cl)cc1C(CC(=O)NCCCN2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O13 compound treatment 0.253 0.00753 0.4 0.4047 1.0 1984478 ChemDiv2_002081 OC(=O)CCc1nn2c3ccccc3nc2n(c4ccccc4)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O14 compound treatment 0.245 -4.69E-4 -0.03 -0.0252 -1.0 1984479 ChemDiv2_002082 CN(C)CCOC(=O)c1c(C)oc2cc3c(C(=O)OCCN(C)C)c(C)oc3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O15 compound treatment 0.273 0.0275 1.48 1.4795 1.0 1984480 ChemDiv2_002083 CC1CCCN(C1)C(=O)c2ccc(NC(=O)C(O)(c3ccccc3)c4ccccc4)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O16 compound treatment 0.264 0.0185 1.0 0.9958 1.0 1984481 ChemDiv2_002084 COC(=O)C(C)(C)C1C(C(=O)c2ccco2)C(=O)Oc3ccc(Br)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O17 compound treatment 0.264 0.0185 1.0 0.9958 1.0 1984482 ChemDiv2_002085 COc1ccc(CCNC2=CC(=O)CC(C)(C)C2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O18 compound treatment 0.266 0.0205 1.1 1.1033 1.0 1984483 ChemDiv2_002086 NC(=O)c1cccc2c(=O)oc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O19 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1984484 ChemDiv2_002087 O=S(=O)(Cc1ccccc1)c2nnnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O20 compound treatment 0.249 0.00353 0.19 0.1898 1.0 1984485 ChemDiv2_002088 CCCN(CCC)C(=O)CC(C1CCOC(C)(C)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O21 compound treatment 0.253 0.00753 0.4 0.4047 1.0 1180549 ChemDiv2_002089 CN(C)S(=O)(=O)N(Cc1ccc(cc1)C(C)(C)C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O22 compound treatment 0.258 0.0125 0.67 0.6734 1.0 1919624 ChemDiv2_002090 CCc1c(C)nn2c1n3nc(C)c(CC)c3n4nc(C)c(CC)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O23 mock treatment 0.266 0.0205 1.1 1.1033 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 O24 mock treatment 0.244 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P01 compound treatment 0.243 -0.00247 -0.13 -0.1327 -1.0 1699911 ChemDiv2_002091 O=c1cc[nH]c2c3nonc3nc(c4ccccc4)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P02 compound treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1984486 ChemDiv2_002092 COc1cc2CCN(C)C3CC4(C=CC(=O)C=C4)c(c32)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P03 compound treatment 0.306 0.0605 3.25 3.2528 1.0 1984487 ChemDiv2_002093 O=C(OCCN1CCCCC1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P04 compound treatment 0.24 -0.00547 -0.29 -0.2939 -1.0 1984488 ChemDiv2_002094 CN(CCc1ccccn1)Cc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P05 compound treatment 0.242 -0.00347 -0.19 -0.1864 -1.0 1984489 ChemDiv2_002095 NC(=O)CSc1nnnn1CC(CC(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P06 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1571315 ChemDiv2_002096 CC1C(=O)CCC1(C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P07 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1984490 ChemDiv2_002097 Fc1ccc(CN2CCC(CC2)N3CCc4ccccc4C3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P08 compound treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1984491 ChemDiv2_002098 Cc1cc(ccc1F)S(=O)(=O)N2CCN=C2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P09 compound treatment 0.261 0.0155 0.83 0.8346 1.0 1984492 ChemDiv2_002099 CC(=O)Nc1ccc(cc1)c2cn(CC(=O)N)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P10 compound treatment 0.215 -0.0305 -1.64 -1.6373 -1.0 1984493 ChemDiv2_002100 CC(C)(CO)NC(=O)C1CCCNC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P11 compound treatment 0.223 -0.0225 -1.21 -1.2074 -1.0 1984494 ChemDiv2_002101 CC(C)c1ccc(OCCN2CCOCC2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P12 compound treatment 0.222 -0.0235 -1.26 -1.2612 -1.0 1984495 ChemDiv2_002102 CC(C)(C)c1cc(N)n(n1)c2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P13 compound treatment 0.222 -0.0235 -1.26 -1.2612 -1.0 1984496 ChemDiv2_002103 OC(=O)CCCN1Cc2ccccc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P14 compound treatment 0.343 0.0975 5.24 5.2411 1.0 1984497 ChemDiv2_002104 O/N=C/c1ccc(cn1)C(=O)NCC2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P15 compound treatment 0.231 -0.0145 -0.78 -0.7775 -1.0 1031623 ChemDiv2_002105 Cc1csc(=S)n1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P16 compound treatment 0.294 0.0485 2.61 2.608 1.0 1984498 ChemDiv2_002106 CCc1c(C)nn2cnnc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P17 compound treatment 0.268 0.0225 1.21 1.2108 1.0 1984499 ChemDiv2_002107 COC(=O)C1(C)Cc2ccccc2C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P18 compound treatment 0.245 -4.69E-4 -0.03 -0.0252 -1.0 1984500 ChemDiv2_002108 Cc1oc2C(=O)c3ccccc3C(=O)c2c1C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P19 compound treatment 0.262 0.0165 0.89 0.8884 1.0 1984501 ChemDiv2_002109 OCc1cn(Cc2ccccc2Cl)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P20 compound treatment 0.443 0.198 10.61 10.6149 1.0 1373828 ChemDiv2_002110 CC(C)Oc1ccccc1NC(=O)c2cccc(c2)C(=O)Nc3ccccc3OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P21 compound treatment 0.369 0.124 6.64 6.6383 1.0 1984502 ChemDiv2_002111 Clc1ccc(NC(=O)c2ccsn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P22 compound treatment 0.233 -0.0125 -0.67 -0.67 -1.0 1984503 ChemDiv2_002112 CCOC(=O)Nc1ccc(Br)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P23 mock treatment 0.235 -0.0105 -0.56 -0.5626 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1374 P24 mock treatment 0.239 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A01 compound treatment 0.24 -4.52E-4 -0.02 -0.0243 -1.0 1914890 ChemDiv2_002113 CC(NC(=O)C1CC1(C)C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A02 compound treatment 0.237 -0.00345 -0.19 -0.1855 -1.0 1267317 ChemDiv2_002114 Oc1ccc2occ(C(=O)c3cccs3)c2c1CN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A03 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1029434 ChemDiv2_002115 CC(=O)Oc1ccc(OCc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A04 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1713707 ChemDiv2_002116 O=c1ccn(Cc2ccccc2)c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A05 compound treatment 0.227 -0.0135 -0.72 -0.7229 -1.0 1314161 ChemDiv2_002117 O=C(Nc1ccccc1)OC2CN3CCC2CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A06 compound treatment 0.263 0.0225 1.21 1.2117 1.0 1129108 ChemDiv2_002118 CC1(C)CC(CC(C)(C)N1)OC(=O)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A07 compound treatment 0.284 0.0435 2.34 2.3402 1.0 1055204 ChemDiv2_002119 CCOc1ccc(cc1)C(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A08 compound treatment 0.45 0.21 11.26 11.2607 1.0 1984504 ChemDiv2_002120 O=C1CCCC1C(C#N)(C#N)C(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A09 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1521460 ChemDiv2_002121 Cn1c2OC(=C(C#N)C(c3ccc(Cl)cc3)c2c(=O)n(C)c1=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A10 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1945035 ChemDiv2_002122 OC(=O)C1NCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A11 compound treatment 0.242 0.00155 0.08 0.0832 1.0 1600077 ChemDiv2_002123 Cc1cccc(NC(=O)C2(CCCCC2)N3CCC3=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A12 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1326255 ChemDiv2_002124 OCC(CO)(CO)c1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A13 compound treatment 0.258 0.0175 0.94 0.943 1.0 1613642 ChemDiv2_002125 Nc1nonc1C(=O)OCC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A14 compound treatment 0.448 0.208 11.15 11.1532 1.0 1984505 ChemDiv2_002126 O=C(OCCCc1nc2ccccc2[nH]1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A15 compound treatment 0.318 0.0775 4.17 4.1673 1.0 1231733 ChemDiv2_002127 Nc1nonc1C(=O)OCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A16 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1984506 ChemDiv2_002128 CCNC(=O)C1OC(C(O)C1O)n2cnc3c(N)ncnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A17 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1938417 ChemDiv2_002129 COC(=O)CN(c1c(C)cccc1C)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A18 compound treatment 0.264 0.0235 1.27 1.2654 1.0 1667440 ChemDiv2_002130 CCCC1C(c2ccccc2)C(C#N)(C#N)C(CC1=O)(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A19 compound treatment 0.259 0.0185 1.0 0.9968 1.0 1164944 ChemDiv2_002131 Nc1nnnn1CC(=O)OCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A20 compound treatment 0.273 0.0325 1.75 1.7491 1.0 1394604 ChemDiv2_002132 COc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A21 compound treatment 0.24 -4.52E-4 -0.02 -0.0243 -1.0 1384799 ChemDiv2_002133 Cc1ccc(cc1)C2N(C(=O)C(=C2S(=O)(=O)C)O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A22 compound treatment 0.232 -0.00845 -0.45 -0.4542 -1.0 1504088 ChemDiv2_002134 CCCC1CC2(O)CC(C#N)(C(=O)N2)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A23 mock treatment 0.24 -4.52E-4 -0.02 -0.0243 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 A24 mock treatment 0.25 0.00955 0.51 0.5131 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B01 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1984507 ChemDiv2_002135 BrCc1ccc2nsnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B02 compound treatment 0.286 0.0455 2.45 2.4477 1.0 1984508 ChemDiv2_002136 Oc1cnc(c2ccccc2)c(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B03 compound treatment 0.386 0.146 7.82 7.8215 1.0 1735610 ChemDiv2_002137 OC(=O)C1CCCc2c1[nH]c3ccc(Br)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B04 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1607014 ChemDiv2_002138 Oc1ccccc1CC2CC3CCN2CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B05 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1305244 ChemDiv2_002139 CC(=CCCC1(C)OC(=O)NC1(C)O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B06 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1984509 ChemDiv2_002140 CC(C)Oc1cccc(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B07 compound treatment 0.447 0.207 11.1 11.0995 1.0 1137379 ChemDiv2_002141 Brc1ccc(Cn2nnc(n2)c3ccc4OCOc4c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B08 compound treatment 0.448 0.208 11.15 11.1532 1.0 1487224 ChemDiv2_002142 Clc1cccc(Cl)c1NC(=O)CSc2nnc3CCCCCn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B09 compound treatment 0.358 0.118 6.32 6.3168 1.0 1984510 ChemDiv2_002143 Brc1cncc(c1)C(=O)NCCSc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B10 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1302662 ChemDiv2_002144 Cc1cccc(C)c1NC(=O)C(N2C(CC2=O)c3ccco3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B11 compound treatment 0.343 0.103 5.51 5.5107 1.0 1147636 ChemDiv2_002145 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B12 compound treatment 0.235 -0.00545 -0.29 -0.293 -1.0 1984511 ChemDiv2_002146 CCCn1cc(C(=O)O)c(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B13 compound treatment 0.342 0.102 5.46 5.457 1.0 1539496 ChemDiv2_002147 CC(C)C(=O)Nc1ccc(Cl)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B14 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1665172 ChemDiv2_002148 Cc1ccc(NC(=O)C2(CCCCC2)N3C(CC3=O)c4ccco4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B15 compound treatment 0.505 0.265 14.22 14.2163 1.0 1563172 ChemDiv2_002149 O=C(Cc1cccs1)Nc2ccc3COC(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B16 compound treatment 0.493 0.253 13.57 13.5714 1.0 1984512 ChemDiv2_002150 COc1ccc(cc1OC)c2csc(=Nc3ccccn3)n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B17 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1562783 ChemDiv2_002151 CC(C)CN(C(=O)Cn1nnnc1N)C2(CCCCC2)C(=O)Nc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B18 compound treatment 0.245 0.00455 0.24 0.2444 1.0 1984513 ChemDiv2_002152 CC1OC(NCCc2ccccc2)C(O)C(O)C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B19 compound treatment 0.253 0.0125 0.67 0.6743 1.0 1984514 ChemDiv2_002153 Cc1cc(C)n(CCO)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B20 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1984515 ChemDiv2_002154 O=C1CC2CS(=O)(=O)CC2N1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B21 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1190525 ChemDiv2_002155 CN(C1CC(C)(C)N(C)C(C)(C)C1)C(=O)CCCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B22 compound treatment 0.23 -0.0105 -0.56 -0.5616 -1.0 1984516 ChemDiv2_002156 NCCCn1cnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B23 mock treatment 0.275 0.0345 1.86 1.8566 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 B24 mock treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C01 compound treatment 0.281 0.0405 2.18 2.179 1.0 1206133 ChemDiv2_002157 CC(=O)N1CCC2(CC1)C3CN(CC=C3C(=C(N)C2(C#N)C#N)C#N)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C02 compound treatment 0.312 0.0715 3.84 3.8449 1.0 1184574 ChemDiv2_002158 CSc1nn(CCc2ccncc2)c(=S)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C03 compound treatment 0.262 0.0215 1.16 1.158 1.0 1923963 ChemDiv2_002159 COc1cccc(OCCNC(=O)Cc2cccc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C04 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1984517 ChemDiv2_002160 CC(C)(O)C#CC(O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C05 compound treatment 0.305 0.0645 3.47 3.4687 1.0 1725779 ChemDiv2_002161 COc1cccc2c(Cl)c(CC=C)c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C06 compound treatment 0.288 0.0475 2.56 2.5552 1.0 1352571 ChemDiv2_002162 Nc1cnn(c2ccccc2)c(=O)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C07 compound treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1113154 ChemDiv2_002163 COc1ccc(cc1)C(CC(=O)O)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C08 compound treatment 0.263 0.0225 1.21 1.2117 1.0 1043938 ChemDiv2_002164 Oc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C09 compound treatment 0.311 0.0705 3.79 3.7911 1.0 1984518 ChemDiv2_002165 Nc1c(C#N)sc2snc(SCC#N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C10 compound treatment 0.258 0.0175 0.94 0.943 1.0 1067661 ChemDiv2_002166 OC(=O)c1ccc2CCc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C11 compound treatment 0.323 0.0825 4.44 4.436 1.0 1984519 ChemDiv2_002167 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3cccs3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C12 compound treatment 0.26 0.0195 1.05 1.0505 1.0 1945775 ChemDiv2_002168 CCSC1(SCC)N=C(N)C2(C#N)C(NC(=CC12C#N)C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C13 compound treatment 0.331 0.0905 4.87 4.8659 1.0 1172399 ChemDiv2_002169 CC(C)(C)OC(=O)COc1ccc2oc(=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C14 compound treatment 0.287 0.0465 2.5 2.5014 1.0 1610822 ChemDiv2_002170 CC1CN(OC(O1)c2cccs2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C15 compound treatment 0.248 0.00755 0.41 0.4056 1.0 1125733 ChemDiv2_002171 COc1cccc(OC)c1C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C16 compound treatment 0.284 0.0435 2.34 2.3402 1.0 1984520 ChemDiv2_002172 Clc1ccc(C(=O)OCn2cncn2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C17 compound treatment 0.257 0.0165 0.89 0.8893 1.0 1984521 ChemDiv2_002173 CC(C)CNC(=O)C(C)c1ccc(CC(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C18 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1142269 ChemDiv2_002174 CC(C)OC(=O)C1CC(C)(O)C(=O)C(C1c2ccc(cc2)N(C)C)C(=O)OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C19 compound treatment 0.345 0.105 5.62 5.6182 1.0 1667616 ChemDiv2_002175 CC(N1C(=O)c2ccccc2C1=O)C(=O)OCC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C20 compound treatment 0.547 0.307 16.47 16.4733 1.0 1984522 ChemDiv2_002176 O=C(CC(C#N)(C#N)C(C#N)C#N)C1CC2CC1C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C21 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1984523 ChemDiv2_002177 CC(C)(C#N)C(C)(C)c1nnn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C22 compound treatment 0.248 0.00755 0.41 0.4056 1.0 1710308 ChemDiv2_002178 CC1(C)OC(=O)N(CCCN2CCOCC2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C23 mock treatment 0.256 0.0155 0.84 0.8355 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 C24 mock treatment 0.248 0.00755 0.41 0.4056 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D01 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1367778 ChemDiv2_002179 Nc1ccc(cc1)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D02 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1359041 ChemDiv2_002180 CC1(NCCc2ccccc21)C3(O)CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D03 compound treatment 0.297 0.0565 3.04 3.0388 1.0 1154308 ChemDiv2_002181 COC(=O)c1ccc(NC(=O)CNc2cc(Cl)ccc2OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D04 compound treatment 0.258 0.0175 0.94 0.943 1.0 1396760 ChemDiv2_002182 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(=O)N4CCOCC4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D05 compound treatment 0.409 0.169 9.06 9.0574 1.0 1364523 ChemDiv2_002183 O=c1[nH]cnc2n(Cc3ccccc3)nnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D06 compound treatment 0.271 0.0305 1.64 1.6416 1.0 1984524 ChemDiv2_002184 CCCOc1cccc(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D07 compound treatment 0.239 -0.00145 -0.08 -0.078 -1.0 1420298 ChemDiv2_002185 Cc1cc(=O)n(C)c(=O)n1CCCN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D08 compound treatment 0.544 0.304 16.31 16.3121 1.0 1536564 ChemDiv2_002186 CCOc1cccc(=O)c2c(C)n(Cc3ccccc3)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D09 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1424315 ChemDiv2_002187 CCC1(C(c2ccc(OC)c(OC)c2)C1(C(=O)OC)C(=O)OC)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D10 compound treatment 0.309 0.0685 3.68 3.6836 1.0 1643908 ChemDiv2_002188 O=C(c1ccccc1)c2ccc3OCC(=O)NCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D11 compound treatment 0.263 0.0225 1.21 1.2117 1.0 1228893 ChemDiv2_002189 Cc1cc(N2CCOCC2)c(F)cc1C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D12 compound treatment 0.459 0.219 11.74 11.7443 1.0 1346867 ChemDiv2_002190 CCOC(=O)c1[nH]c(C)c(CN(C2CCCCC2)S(=O)(=O)C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D13 compound treatment 0.295 0.0545 2.93 2.9313 1.0 1285386 ChemDiv2_002191 COc1ccc(C(=O)c2ccccc2)c(OCC(=O)NC3CC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D14 compound treatment 0.265 0.0245 1.32 1.3192 1.0 1390047 ChemDiv2_002192 COc1ccc(cc1OC)C2CC(=O)N2C(C(=O)Nc3c(C)cccc3C)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D15 compound treatment 0.544 0.304 16.31 16.3121 1.0 1306785 ChemDiv2_002193 COC(=O)c1cccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D16 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1984525 ChemDiv2_002194 NCc1ccccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D17 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1338030 ChemDiv2_002195 CN(C1CC(C)(C)N(C)C(C)(C)C1)C(=O)c2ccc(cc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D18 compound treatment 0.393 0.153 8.2 8.1976 1.0 1984526 ChemDiv2_002196 Clc1cccc(NC(=O)c2scc3OCCOc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D19 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1252500 ChemDiv2_002197 CCC1N(CC1=O)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D20 compound treatment 0.222 -0.0185 -0.99 -0.9916 -1.0 1984527 ChemDiv2_002198 O=C1CC2CS(=O)(=O)CC2N1Cc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D21 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1570677 ChemDiv2_002199 OC(=O)c1cccnc1Oc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D22 compound treatment 0.445 0.205 10.99 10.992 1.0 1984528 ChemDiv2_002200 CC(=O)Nc1ccc(Oc2cc(C#N)c(C#N)cc2N3CCCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D23 mock treatment 0.241 5.48E-4 0.03 0.0295 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 D24 mock treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E01 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1984529 ChemDiv2_002201 Cc1oc(CSCc2cc(C(=O)O)c(C)o2)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E02 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1156093 ChemDiv2_002202 CCC1(C)OC(=O)N2CCc3cc(OC)c(OC)cc3C21C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E03 compound treatment 0.244 0.00355 0.19 0.1907 1.0 1018435 ChemDiv2_002203 O=C(C(c1ccccc1)c2ccccc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E04 compound treatment 0.545 0.305 16.37 16.3658 1.0 1352523 ChemDiv2_002204 CC(=O)Oc1ccc2occ(C(=O)c3cccs3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E05 compound treatment 0.24 -4.52E-4 -0.02 -0.0243 -1.0 1984530 ChemDiv2_002205 COc1ccc2nnnn2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E06 compound treatment 0.245 0.00455 0.24 0.2444 1.0 1689798 ChemDiv2_002206 CC1(C)CC(CCO)CC(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E07 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1937411 ChemDiv2_002207 CC(C)(C)c1cc(Cc2ccccc2)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E08 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1723958 ChemDiv2_002208 CCOC(=O)C1CSC(CC(=O)Nc2ccccc2)C(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E09 compound treatment 0.331 0.0905 4.87 4.8659 1.0 1221421 ChemDiv2_002209 Nc1nonc1n2nnc3C(=O)CCCc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E10 compound treatment 0.253 0.0125 0.67 0.6743 1.0 1647910 ChemDiv2_002210 CC(NC(=O)C(c1ccccc1)c2ccccc2)C(=O)Nc3ccc(C)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E11 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1984531 ChemDiv2_002211 C=CCNC(=O)c1cc(=O)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E12 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1984532 ChemDiv2_002212 Cn1cc(Br)c(n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E13 compound treatment 0.248 0.00755 0.41 0.4056 1.0 1523285 ChemDiv2_002213 CC1(C)CC(=C(CC(=O)Nc2ccc(cc2)S(=O)(=O)N)C(=O)C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E14 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1125457 ChemDiv2_002214 CC(C)(C)C(=O)CC(C)(O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E15 compound treatment 0.339 0.0985 5.3 5.2958 1.0 1445227 ChemDiv2_002215 O=C(NC1CCCCC1)c2ccc3nsnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E16 compound treatment 0.406 0.166 8.9 8.8962 1.0 1257088 ChemDiv2_002216 Cc1nc2cc(NCc3ccccc3O)ccc2n1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E17 compound treatment 0.275 0.0345 1.86 1.8566 1.0 1456372 ChemDiv2_002217 Cc1ccc(NC(=O)c2c[nH]c(=O)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E18 compound treatment 0.239 -0.00145 -0.08 -0.078 -1.0 1984533 ChemDiv2_002218 CC(C)N1CC(CC1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E19 compound treatment 0.266 0.0255 1.37 1.3729 1.0 1236131 ChemDiv2_002219 O=C1OC2(CCCCC2)C(=C1)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E20 compound treatment 0.286 0.0455 2.45 2.4477 1.0 1230351 ChemDiv2_002220 CNc1nn2nnnc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E21 compound treatment 0.239 -0.00145 -0.08 -0.078 -1.0 1563692 ChemDiv2_002221 Cn1nnnc1CN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E22 compound treatment 0.397 0.157 8.41 8.4126 1.0 1064932 ChemDiv2_002222 COc1ccc(cc1OC)C(=O)OC2CC3CCC(C2)N3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E23 mock treatment 0.252 0.0115 0.62 0.6206 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 E24 mock treatment 0.239 -0.00145 -0.08 -0.078 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F01 compound treatment 0.3 0.0595 3.2 3.2 1.0 1586229 ChemDiv2_002223 Cc1cc(NC(=O)c2cccs2)cc(C)c1OCC(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F02 compound treatment 0.377 0.137 7.34 7.3378 1.0 1928034 ChemDiv2_002224 OC(=O)c1ccccc1SCC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F03 compound treatment 0.287 0.0465 2.5 2.5014 1.0 1192200 ChemDiv2_002225 CCOC(=O)CSc1nnnn1c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F04 compound treatment 0.306 0.0655 3.52 3.5224 1.0 1984534 ChemDiv2_002226 CC1(C)C(C#N)C(=O)NC(=C1C#N)SCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F05 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1449744 ChemDiv2_002227 CC1CN(CCC1=O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F06 compound treatment 0.276 0.0355 1.91 1.9103 1.0 1005124 ChemDiv2_002228 OCCOc1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F07 compound treatment 0.304 0.0635 3.41 3.415 1.0 1173890 ChemDiv2_002229 OC(=O)CCC(=O)N(Cc1cccs1)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F08 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1559634 ChemDiv2_002230 CC(=O)NC1(C)CCC(C1)C(C)(C)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F09 compound treatment 0.333 0.0925 4.97 4.9734 1.0 1683024 ChemDiv2_002231 COc1ccc(cc1)C2CC3(C)CC(=O)C2C(C#N)(C#N)C3(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F10 compound treatment 0.465 0.225 12.07 12.0668 1.0 1638063 ChemDiv2_002232 CCNS(=O)(=O)c1c(C)cc(cc1C)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F11 compound treatment 0.28 0.0395 2.13 2.1252 1.0 1526320 ChemDiv2_002233 Nc1nc(cs1)c2ccc(N3CCOCC3)c(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F12 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1350374 ChemDiv2_002234 COc1ccc(Cl)cc1S(=O)(=O)Nc2ccc(CC(=O)O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F13 compound treatment 0.279 0.0385 2.07 2.0715 1.0 1368650 ChemDiv2_002235 CC(C)Cc1cc(C(=O)Nc2ccccc2C(=O)O)c(C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F14 compound treatment 0.487 0.247 13.25 13.249 1.0 1984535 ChemDiv2_002236 CCOC(=O)c1ccc(CNS(=O)(=O)c2cccc(c2)S(=O)(=O)c3ccc(Cl)cc3)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F15 compound treatment 0.313 0.0725 3.9 3.8986 1.0 1984536 ChemDiv2_002237 O=C(CSCc1ccccc1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F16 compound treatment 0.453 0.213 11.42 11.4219 1.0 1984537 ChemDiv2_002238 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)OCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F17 compound treatment 0.248 0.00755 0.41 0.4056 1.0 1412383 ChemDiv2_002239 COC(=O)c1ccccc1S(=O)(=O)NCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F18 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1984538 ChemDiv2_002240 CC1(C)CC(CC(C)(C)N1)NC(=O)c2scc3OCCOc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F19 compound treatment 0.36 0.12 6.42 6.4243 1.0 1424171 ChemDiv2_002241 Brc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F20 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1734127 ChemDiv2_002242 O=C(CC1CCS(=O)(=O)C1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F21 compound treatment 0.231 -0.00945 -0.51 -0.5079 -1.0 1984539 ChemDiv2_002243 CC(C)C1CC(O)(ON1)C2(O)CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F22 compound treatment 0.243 0.00255 0.14 0.1369 1.0 1984540 ChemDiv2_002244 CC1=C(C(=O)N2CCCCC2)S(=O)(=O)C(=C1C#N)NC(=O)CC3CCS(=O)(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F23 mock treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 F24 mock treatment 0.229 -0.0115 -0.62 -0.6154 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G01 compound treatment 0.407 0.167 8.95 8.95 1.0 1984541 ChemDiv2_002245 O/N=C(\COC(=O)c1ccc(Br)cc1)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G02 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1984542 ChemDiv2_002246 Cc1[nH]nc(O)c1C(C(C#N)C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G03 compound treatment 0.272 0.0315 1.7 1.6953 1.0 1377554 ChemDiv2_002247 COC(=O)c1nnc(c2ccccc2)c(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G04 compound treatment 0.243 0.00255 0.14 0.1369 1.0 1505380 ChemDiv2_002248 CN1CCc2c(C1)nnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G05 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1984543 ChemDiv2_002249 CC(=O)Oc1ccc2n(C)c(C)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G06 compound treatment 0.329 0.0885 4.76 4.7584 1.0 1015393 ChemDiv2_002250 CCCC(=O)c1ccc(O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G07 compound treatment 0.602 0.362 19.43 19.4289 1.0 1364226 ChemDiv2_002251 Cc1cc(=O)oc2cc(OC(=O)CSc3nc(Cc4ccccc4)cc(=O)[nH]3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G08 compound treatment 0.232 -0.00845 -0.45 -0.4542 -1.0 1603960 ChemDiv2_002252 CC(C)N1CC(C)C(CC1C)OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G09 compound treatment 0.277 0.0365 1.96 1.964 1.0 1711644 ChemDiv2_002253 CC(NC(=O)OCc1ccccc1)C(=O)Nc2ccc(C)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G10 compound treatment 0.27 0.0295 1.59 1.5879 1.0 1234139 ChemDiv2_002254 O=C1CCC(=O)N1c2ccc(Oc3ccc(C#N)cc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G11 compound treatment 0.277 0.0365 1.96 1.964 1.0 1554503 ChemDiv2_002255 CC1(C)Cc2c(CO1)sc3c2c(=O)n(c4ccccc4)c5nnnn53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G12 compound treatment 0.23 -0.0105 -0.56 -0.5616 -1.0 1431990 ChemDiv2_002256 Oc1nsnc1N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G13 compound treatment 0.43 0.19 10.19 10.1859 1.0 1398204 ChemDiv2_002257 COC(=O)c1cccc(NC(=O)COC(=O)c2ccc(cc2)N3C(=O)CCC3=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G14 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1984544 ChemDiv2_002258 CN(C)c1c[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G15 compound treatment 0.244 0.00355 0.19 0.1907 1.0 1535765 ChemDiv2_002259 CC1CC(O)(Cc2ccccc2)C(C)CN1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G16 compound treatment 0.259 0.0185 1.0 0.9968 1.0 1683486 ChemDiv2_002260 COc1ccc(OC)c(c1)C(O)c2nc3ccccc3n2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G17 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1216646 ChemDiv2_002261 CC(=O)N(C(=O)C)c1ccccc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G18 compound treatment 0.304 0.0635 3.41 3.415 1.0 1184853 ChemDiv2_002262 Cc1ccc(Oc2ccc(cc2C(=O)N)S(=O)(=O)N3CCOCC3)c(c1)n4nc5ccccc5n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G19 compound treatment 0.469 0.229 12.28 12.2817 1.0 1195341 ChemDiv2_002263 Nc1ccc(Sc2ccc(cc2)N3C(=O)c4ccc(N)cc4C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G20 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1984545 ChemDiv2_002264 CC(=O)n1c(=O)n(C(=O)C)c2cc(Br)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G21 compound treatment 0.26 0.0195 1.05 1.0505 1.0 1027021 ChemDiv2_002265 OC(=O)C(Cc1cccs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G22 compound treatment 0.261 0.0205 1.1 1.1042 1.0 1449194 ChemDiv2_002266 Cc1ccc(cc1)N2CCSC2c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G23 mock treatment 0.239 -0.00145 -0.08 -0.078 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 G24 mock treatment 0.241 5.48E-4 0.03 0.0295 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H01 compound treatment 0.292 0.0515 2.77 2.7701 1.0 1585592 ChemDiv2_002267 OC(=O)COc1cccc(NC(=O)c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H02 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1638139 ChemDiv2_002268 CC(C)(NC(=O)c1ccco1)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H03 compound treatment 0.367 0.127 6.8 6.8004 1.0 1334062 ChemDiv2_002269 CCOC(=O)C1(C#N)C(C2CCCCC2=C(C#N)C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H04 compound treatment 0.412 0.172 9.22 9.2187 1.0 1468560 ChemDiv2_002270 Brc1cccc(Cn2ncc3ccccc3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H05 compound treatment 0.263 0.0225 1.21 1.2117 1.0 1013622 ChemDiv2_002271 Nc1c(nnn1Cc2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H06 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1287833 ChemDiv2_002272 CCOc1ccc(CC(=O)NCc2cn(C)nc2C)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H07 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1314148 ChemDiv2_002273 CC(=O)OC(C#CCN1CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H08 compound treatment 0.52 0.28 15.02 15.0223 1.0 1984546 ChemDiv2_002274 CCOC(=O)c1ccc(cc1)c2nnc(COc3cccc(C)c3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H09 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1456485 ChemDiv2_002275 COc1ccc(CNC2CCCC2)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H10 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1444846 ChemDiv2_002276 CCCN(CCC)S(=O)(=O)c1ncn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H11 compound treatment 0.287 0.0465 2.5 2.5014 1.0 1693020 ChemDiv2_002277 O=C(NC1(CCCCC1)C(=O)Nc2ccccc2)c3ccc(cc3)n4cnnn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H12 compound treatment 0.269 0.0285 1.53 1.5341 1.0 1984547 ChemDiv2_002278 CCOc1ccc(CC(=O)Nc2ccc(C/C(=N/O)/N)cc2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H13 compound treatment 0.226 -0.0145 -0.78 -0.7766 -1.0 1600641 ChemDiv2_002279 COC(=O)Cn1n(CC(=O)OC)c(=O)n(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H14 compound treatment 0.235 -0.00545 -0.29 -0.293 -1.0 1669492 ChemDiv2_002280 Nc1cc(Nc2ccccc2)ccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H15 compound treatment 0.257 0.0165 0.89 0.8893 1.0 1741877 ChemDiv2_002281 COc1ccc(NC(=O)C2(CCCCC2)N(C(=O)c3ccc(cc3)n4cnnn4)c5ccc(OC)cc5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H16 compound treatment 0.546 0.306 16.42 16.4195 1.0 1343649 ChemDiv2_002282 O=C(Nc1ccc(cc1)c2nnc(o2)c3ccco3)C(c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H17 compound treatment 0.237 -0.00345 -0.19 -0.1855 -1.0 1284538 ChemDiv2_002283 CC1(O)N(C2CC2)C(=O)OC31CC(C)(C)NC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H18 compound treatment 0.267 0.0265 1.43 1.4267 1.0 1984548 ChemDiv2_002284 NS(=O)(=O)c1ccc(CNC(=O)c2scc3OCCOc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H19 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1694992 ChemDiv2_002285 CN(C1CC(C)(C)N(C)C(C)(C)C1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H20 compound treatment 0.237 -0.00345 -0.19 -0.1855 -1.0 1984549 ChemDiv2_002286 O=C(Nc1ccccc1)OC2CS(=O)(=O)CC2N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H21 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1160264 ChemDiv2_002287 O=C1CC2CS(=O)(=O)CC2N1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H22 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1984550 ChemDiv2_002288 COC(=O)C1=C(C(Nc2nnnn12)c3ccc(OC)c(OC)c3)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H23 mock treatment 0.231 -0.00945 -0.51 -0.5079 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 H24 mock treatment 0.235 -0.00545 -0.29 -0.293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I01 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1303796 ChemDiv2_002289 COc1ccccc1NC(=O)CCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I02 compound treatment 0.333 0.0925 4.97 4.9734 1.0 1132667 ChemDiv2_002290 CCOC(=O)c1cn(nn1)c2nonc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I03 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1579008 ChemDiv2_002291 COc1cc(Cn2cnnn2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I04 compound treatment 0.27 0.0295 1.59 1.5879 1.0 1207430 ChemDiv2_002292 OC1=NS(=O)(=O)C(=C1O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I05 compound treatment 0.267 0.0265 1.43 1.4267 1.0 1323909 ChemDiv2_002293 CCC(C)SCc1cc(oc1C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I06 compound treatment 0.252 0.0115 0.62 0.6206 1.0 1984551 ChemDiv2_002294 CCNc1nc(SC)ncc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I07 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1138711 ChemDiv2_002295 O=C(CN1C(=O)CCC1=O)N(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I08 compound treatment 0.232 -0.00845 -0.45 -0.4542 -1.0 1316868 ChemDiv2_002296 Clc1ccc(NC(=O)C2C3C2C4CCC3C4)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I09 compound treatment 0.242 0.00155 0.08 0.0832 1.0 1453168 ChemDiv2_002297 CCC1(C)OC(=O)N(c2ccc(C)cc2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I10 compound treatment 0.273 0.0325 1.75 1.7491 1.0 1442826 ChemDiv2_002298 Cc1ccc(cc1)C2OCC3(CO)COC(N23)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I11 compound treatment 0.341 0.101 5.4 5.4033 1.0 1462703 ChemDiv2_002299 NS(=O)(=O)c1ccc(NC(=O)COC(=O)CN2C(=O)CCC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I12 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1984552 ChemDiv2_002300 CN(Cc1ccccc1)S(=O)(=O)c2ncn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I13 compound treatment 0.318 0.0775 4.17 4.1673 1.0 1984553 ChemDiv2_002301 O=C(CSC1=NCCS1)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I14 compound treatment 0.311 0.0705 3.79 3.7911 1.0 1786317 ChemDiv2_002302 OC(=O)CCSc1nc(=O)c2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I15 compound treatment 0.527 0.287 15.4 15.3985 1.0 1140460 ChemDiv2_002303 COc1cc(CNS(=O)(=O)c2ccc(CN3C(=O)c4ccccc4C3=O)cc2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I16 compound treatment 0.258 0.0175 0.94 0.943 1.0 1984554 ChemDiv2_002304 CCCC1C(C)C(C#N)(C#N)C(CC1=O)(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I17 compound treatment 0.315 0.0745 4.01 4.0061 1.0 1984555 ChemDiv2_002305 CCc1cc2c(=O)[nH]cnc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I18 compound treatment 0.259 0.0185 1.0 0.9968 1.0 1652887 ChemDiv2_002306 CC(C)COC(=O)N1CCCC1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I19 compound treatment 0.276 0.0355 1.91 1.9103 1.0 1285566 ChemDiv2_002307 COc1ccc(CCC(=O)C2(O)CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I20 compound treatment 0.259 0.0185 1.0 0.9968 1.0 1984556 ChemDiv2_002308 CCCc1cc(C(=O)O)n(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I21 compound treatment 0.464 0.224 12.01 12.013 1.0 1984557 ChemDiv2_002309 COC(=O)CCC(=O)c1cc2ccccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I22 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1984558 ChemDiv2_002310 CCOC(=O)Cc1nnn(CC(=O)OCC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I23 mock treatment 0.242 0.00155 0.08 0.0832 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 I24 mock treatment 0.241 5.48E-4 0.03 0.0295 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J01 compound treatment 0.267 0.0265 1.43 1.4267 1.0 1469512 ChemDiv2_002311 COC(=O)Cn1nc2-c3ccccc3C(=O)c4cccc1c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J02 compound treatment 0.259 0.0185 1.0 0.9968 1.0 1405553 ChemDiv2_002312 N=C1OC23CCCCC3C1(C#N)C(C#N)(C#N)C(O2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J03 compound treatment 0.26 0.0195 1.05 1.0505 1.0 1618063 ChemDiv2_002313 CCOC(=O)C1C(C(C(=O)OCC)C(=O)CC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J04 compound treatment 0.269 0.0285 1.53 1.5341 1.0 1116093 ChemDiv2_002314 CC(=O)Nc1ccc(OCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J05 compound treatment 0.298 0.0575 3.09 3.0925 1.0 1700711 ChemDiv2_002315 COC(=O)CNc1ccccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J06 compound treatment 0.271 0.0305 1.64 1.6416 1.0 1139331 ChemDiv2_002316 Cc1[nH]c2ccccc2c1CCn3c(N)cc(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J07 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1882006 ChemDiv2_002317 Nc1cc(=O)[nH]c(SCCC(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J08 compound treatment 0.233 -0.00745 -0.4 -0.4004 -1.0 1719389 ChemDiv2_002318 COc1cccc2C(=CC(C)(C)Nc12)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J09 compound treatment 0.259 0.0185 1.0 0.9968 1.0 1984559 ChemDiv2_002319 COc1ccc(cc1O)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J10 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1786274 ChemDiv2_002320 Cc1cc(=O)[nH]c(NCCO)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J11 compound treatment 0.245 0.00455 0.24 0.2444 1.0 1392886 ChemDiv2_002321 CC1(C)CC(CC(C)(C)N1)NC2CC(C)(C)NC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J12 compound treatment 0.499 0.259 13.89 13.8938 1.0 1471394 ChemDiv2_002322 O=C(COc1ccc2CCCc2c1)Nc3ccc(CC#N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J13 compound treatment 0.303 0.0625 3.36 3.3612 1.0 1984560 ChemDiv2_002323 COc1ccc2C(C3=C(O)CCCC3=O)C4=C(CCCC4=O)Oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J14 compound treatment 0.304 0.0635 3.41 3.415 1.0 1984561 ChemDiv2_002324 CCOc1cccc(CNCC2NCCc3ccccc23)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J15 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1515903 ChemDiv2_002325 CC(C)(O)C1(C)N(Cc2ccccc2)CCc3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J16 compound treatment 0.485 0.245 13.14 13.1415 1.0 1604669 ChemDiv2_002326 O=C(Cc1ccccc1)Nc2ccc(cc2)c3nnc(o3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J17 compound treatment 0.261 0.0205 1.1 1.1042 1.0 1469093 ChemDiv2_002327 O=C(NC1(CC1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J18 compound treatment 0.47 0.23 12.34 12.3355 1.0 1984562 ChemDiv2_002328 CC(C)OC(=O)c1ccc(NC(=O)CSc2nnc(c3ccco3)n2CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J19 compound treatment 0.237 -0.00345 -0.19 -0.1855 -1.0 1391383 ChemDiv2_002329 CC(C)CN(C(=O)Cn1nnnc1N)C2(CCCCC2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J20 compound treatment 0.244 0.00355 0.19 0.1907 1.0 1984563 ChemDiv2_002330 OC(=O)c1ccc(cc1)C2NCc3ccccc3-n4cccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J21 compound treatment 0.243 0.00255 0.14 0.1369 1.0 1732580 ChemDiv2_002331 O=C(CC1CS(=O)(=O)CC1CC(=O)NCc2ccccc2)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J22 compound treatment 0.222 -0.0185 -0.99 -0.9916 -1.0 1984564 ChemDiv2_002332 O=c1[nH]nc(c2ccccc2)c3C(Nc4nnnn4-c31)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J23 mock treatment 0.235 -0.00545 -0.29 -0.293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 J24 mock treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K01 compound treatment 0.269 0.0285 1.53 1.5341 1.0 1928098 ChemDiv2_002333 O=C(CCc1ccccc1)NCCOc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K02 compound treatment 0.271 0.0305 1.64 1.6416 1.0 1641559 ChemDiv2_002334 COC(=O)c1cccc(NC2=CC(C)(C)CC(=O)C2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K03 compound treatment 0.273 0.0325 1.75 1.7491 1.0 1984565 ChemDiv2_002335 CSc1sc2c(N)nc(N)nc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K04 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1640248 ChemDiv2_002336 CC(C)(O)C#CC(O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K05 compound treatment 0.499 0.259 13.89 13.8938 1.0 1546314 ChemDiv2_002337 O=C(Nc1ccc2C(=O)NC(=O)c2c1)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K06 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1613727 ChemDiv2_002338 OC1(CCCCC1)C#CCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K07 compound treatment 0.312 0.0715 3.84 3.8449 1.0 1145104 ChemDiv2_002339 CC(N1C(=O)CCC1=O)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K08 compound treatment 0.242 0.00155 0.08 0.0832 1.0 1634455 ChemDiv2_002340 Fc1ccc2C(=O)N(C3CC3)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K09 compound treatment 0.281 0.0405 2.18 2.179 1.0 1389979 ChemDiv2_002341 Cc1nonc1c2csc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K10 compound treatment 0.283 0.0425 2.29 2.2865 1.0 1184425 ChemDiv2_002342 Oc1c(Br)cc(CN2CCOCC2)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K11 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1715493 ChemDiv2_002343 CC1CN(C)C(C)CC1Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K12 compound treatment 0.494 0.254 13.63 13.6252 1.0 1984566 ChemDiv2_002344 CC1=NC(=O)C2C(=O)O/C(=C/c3ccc4OCOc4c3)/C2=C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K13 compound treatment 0.253 0.0125 0.67 0.6743 1.0 1623860 ChemDiv2_002345 Nc1c(c(nn1Cc2ccccc2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K14 compound treatment 0.245 0.00455 0.24 0.2444 1.0 1619011 ChemDiv2_002346 CN(C1CC(C)(C)NC(C)(C)C1)S(=O)(=O)CC2(CCC3CC2=O)C3(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K15 compound treatment 0.248 0.00755 0.41 0.4056 1.0 1984567 ChemDiv2_002347 CCC(Cc1cc(OC)c(C)cc1OC)NC(=O)c2ccc(F)c(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K16 compound treatment 0.242 0.00155 0.08 0.0832 1.0 1187697 ChemDiv2_002348 CCCC1OC23CCCCC3C(C#N)(C(=N)O2)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K17 compound treatment 0.253 0.0125 0.67 0.6743 1.0 1416276 ChemDiv2_002349 CC(=CCCC1(C)OC(=O)N(CC=C)C1(C)O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K18 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1984568 ChemDiv2_002350 CC(C)(C)C/1=NOC(=O)\C1=N\O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K19 compound treatment 0.264 0.0235 1.27 1.2654 1.0 1419260 ChemDiv2_002351 NC(=O)c1ccc2CCc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K20 compound treatment 0.289 0.0485 2.61 2.6089 1.0 1603163 ChemDiv2_002352 O=C(CSc1nnc(s1)N2C(=O)c3ccccc3C2=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K21 compound treatment 0.243 0.00255 0.14 0.1369 1.0 1422964 ChemDiv2_002353 COc1ccccc1OCCN2CCN(CCOc3ccccc3OC)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K22 compound treatment 0.245 0.00455 0.24 0.2444 1.0 1455958 ChemDiv2_002354 CCC(O)(CC)C#CCN1CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K23 mock treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 K24 mock treatment 0.247 0.00655 0.35 0.3519 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L01 compound treatment 0.293 0.0525 2.82 2.8238 1.0 1984569 ChemDiv2_002355 CCc1c(C)n2nc(C)cc2nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L02 compound treatment 0.54 0.3 16.1 16.0971 1.0 1296737 ChemDiv2_002356 O=C(COc1ccccc1C#N)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L03 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1373553 ChemDiv2_002357 CN(C(=O)c1ccc2ccccc2n1)C3(CCCC3)C(=O)Nc4c(C)cccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L04 compound treatment 0.262 0.0215 1.16 1.158 1.0 1492113 ChemDiv2_002358 O=C1C2=C(NC3=C(C2c4ccco4)C(=O)CCC3)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L05 compound treatment 0.39 0.15 8.04 8.0364 1.0 1578141 ChemDiv2_002359 CC(C)(CO)NC(=O)COc1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L06 compound treatment 0.277 0.0365 1.96 1.964 1.0 1670207 ChemDiv2_002360 NC(=O)c1ccccc1NC(=O)c2ccc(cc2)C(=O)N(C3CCCCC3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L07 compound treatment 0.328 0.0875 4.7 4.7047 1.0 1115375 ChemDiv2_002361 COC(=O)c1sc(C(=O)OC)c(O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L08 compound treatment 0.242 0.00155 0.08 0.0832 1.0 1552413 ChemDiv2_002362 COC(=O)C1(C#N)C(c2ccccc2)C1(C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L09 compound treatment 0.457 0.217 11.64 11.6369 1.0 1140194 ChemDiv2_002363 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc(OCC(=O)N3CCOCC3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L10 compound treatment 0.281 0.0405 2.18 2.179 1.0 1984570 ChemDiv2_002364 C(Sc1nncn1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L11 compound treatment 0.263 0.0225 1.21 1.2117 1.0 1679096 ChemDiv2_002365 Brc1cncc(c1)C(=O)NC2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L12 compound treatment 0.258 0.0175 0.94 0.943 1.0 1128991 ChemDiv2_002366 COC(=O)C(C1CCCC1)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L13 compound treatment 0.37 0.13 6.96 6.9617 1.0 1984571 ChemDiv2_002367 Cc1cccc(C)c1OCCNC(=O)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L14 compound treatment 0.387 0.147 7.88 7.8752 1.0 1984572 ChemDiv2_002368 CC1CC(=O)C2=C(O1)c3c(NC2c4ccc(Cl)cc4Cl)ccc5ncccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L15 compound treatment 0.328 0.0875 4.7 4.7047 1.0 1511122 ChemDiv2_002369 COc1cc(ccc1O)C(N(C)C(=O)c2ccc(cc2)n3cnnn3)C(=O)Nc4c(C)cccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L16 compound treatment 0.318 0.0775 4.17 4.1673 1.0 1984573 ChemDiv2_002370 CCn1cc(C(=O)Nc2ccc(CC#N)cc2)c(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L17 compound treatment 0.261 0.0205 1.1 1.1042 1.0 1551487 ChemDiv2_002371 CS(=O)(=O)NCCc1nc(cs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L18 compound treatment 0.348 0.108 5.78 5.7794 1.0 1984574 ChemDiv2_002372 CCN(CC)c1nc([nH]c(=O)n1)N(CC)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L19 compound treatment 0.253 0.0125 0.67 0.6743 1.0 1984575 ChemDiv2_002373 OCCNc1[nH]c(=O)[nH]c(=O)c1I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L20 compound treatment 0.244 0.00355 0.19 0.1907 1.0 1984576 ChemDiv2_002374 COC(=O)c1ccc(CC#N)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L21 compound treatment 0.307 0.0665 3.58 3.5762 1.0 1984577 ChemDiv2_002375 COC(=O)CSc1cc2SCC(=O)Nc3c(sc(c1)c32)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L22 compound treatment 0.244 0.00355 0.19 0.1907 1.0 1984578 ChemDiv2_002376 CC(O)CC#CCN1CCCC(C1)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L23 mock treatment 0.241 5.48E-4 0.03 0.0295 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 L24 mock treatment 0.231 -0.00945 -0.51 -0.5079 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M01 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1420215 ChemDiv2_002377 COc1ccc(cc1)C(C)NC(=O)CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M02 compound treatment 0.267 0.0265 1.43 1.4267 1.0 1984579 ChemDiv2_002378 CSc1cccc2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M03 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1667073 ChemDiv2_002379 CC1(C)Cc2c(C#N)c(=O)[nH]c(c3ccco3)c2CO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M04 compound treatment 0.261 0.0205 1.1 1.1042 1.0 1208265 ChemDiv2_002380 Clc1cccc(c1)C2NC(=O)Cc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M05 compound treatment 0.272 0.0315 1.7 1.6953 1.0 1527863 ChemDiv2_002381 COc1ccc(cc1Br)C2CC(=O)NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M06 compound treatment 0.266 0.0255 1.37 1.3729 1.0 1984580 ChemDiv2_002382 Brc1cnn(c1)C(=O)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M07 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1176996 ChemDiv2_002383 CC(C)(CO)NC(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M08 compound treatment 0.293 0.0525 2.82 2.8238 1.0 1937650 ChemDiv2_002384 C(c1ccccc1)n2nnnc2c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M09 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1339951 ChemDiv2_002385 COc1cc(OC)cc(c1)C(=O)NC2CCCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M10 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1984581 ChemDiv2_002386 Nc1nnc(CS(=O)(=O)c2ccc(Cl)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M11 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1686611 ChemDiv2_002387 O=C(CSCC(=O)Nc1ccccc1)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M12 compound treatment 0.288 0.0475 2.56 2.5552 1.0 1984582 ChemDiv2_002388 O/N=C(/c1nonc1\C(=N\O)\c2ccccc2)\c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M13 compound treatment 0.385 0.145 7.77 7.7677 1.0 1656452 ChemDiv2_002389 Cc1cccc(c1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M14 compound treatment 0.403 0.163 8.74 8.735 1.0 1563593 ChemDiv2_002390 CC(O)c1c(O)ccc2ccc(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M15 compound treatment 0.271 0.0305 1.64 1.6416 1.0 1602258 ChemDiv2_002391 COc1ccccc1NC(=O)C2C(C)C3c4ccccc4C2c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M16 compound treatment 0.249 0.00855 0.46 0.4594 1.0 1984583 ChemDiv2_002392 Cc1ccc(N)c(C(=O)O)c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M17 compound treatment 0.39 0.15 8.04 8.0364 1.0 1984584 ChemDiv2_002393 CC(C)Oc1ccccc1NC(=O)CSc2nnc(c3ccco3)n2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M18 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1492223 ChemDiv2_002394 CC(=O)OC1CCNC2CCCCC12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M19 compound treatment 0.244 0.00355 0.19 0.1907 1.0 1129125 ChemDiv2_002395 CC1(C)CC(CC(C)(C)N1)OC(=O)CCC(=O)OC2CC(C)(C)NC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M20 compound treatment 0.24 -4.52E-4 -0.02 -0.0243 -1.0 1273960 ChemDiv2_002396 CCn1ccnc1C(O)c2cc(OC)ccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M21 compound treatment 0.421 0.181 9.7 9.7023 1.0 1145770 ChemDiv2_002397 OC(=O)C1(CC2c3ccccc3C1c4ccccc24)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M22 compound treatment 0.283 0.0425 2.29 2.2865 1.0 1425325 ChemDiv2_002398 CCOC(=O)C1SCCN1c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M23 mock treatment 0.239 -0.00145 -0.08 -0.078 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 M24 mock treatment 0.244 0.00355 0.19 0.1907 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N01 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1346828 ChemDiv2_002399 CN1C(C)(C)CC(CC1(C)C)NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N02 compound treatment 0.243 0.00255 0.14 0.1369 1.0 1707504 ChemDiv2_002400 COC(CN)c1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N03 compound treatment 0.243 0.00255 0.14 0.1369 1.0 1984585 ChemDiv2_002401 CN1C(ON=C(C)C1(C)C)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N04 compound treatment 0.276 0.0355 1.91 1.9103 1.0 1141056 ChemDiv2_002402 COc1ccccc1C(CCN)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N05 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1500010 ChemDiv2_002403 COc1ccc(cc1OC)c2nnn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N06 compound treatment 0.261 0.0205 1.1 1.1042 1.0 1729268 ChemDiv2_002404 CC(C)(C)NC(=O)CSc1nnc(c2ccco2)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N07 compound treatment 0.278 0.0375 2.02 2.0178 1.0 1651111 ChemDiv2_002405 COc1ccc(CNC(=O)c2cncc(Br)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N08 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1984586 ChemDiv2_002406 COC(=O)C1(C(c2ccc(Cl)cc2)C1(C#N)C#N)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N09 compound treatment 0.359 0.119 6.37 6.3705 1.0 1685036 ChemDiv2_002407 CCS(=O)(=O)N1CCC(CC1)C(=O)OCC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N10 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1420379 ChemDiv2_002408 OC(=O)C1(CCC1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N11 compound treatment 0.33 0.0895 4.81 4.8121 1.0 1984587 ChemDiv2_002409 CSc1ccccc1C(=O)NCCOc2ccccc2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N12 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1342262 ChemDiv2_002410 Cc1ccccc1NS(=O)(=O)c2ccc(cc2)n3c(=O)n(C)n(C)c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N13 compound treatment 0.231 -0.00945 -0.51 -0.5079 -1.0 1490467 ChemDiv2_002411 CC(N1C(=O)OC(C)(C)C1(C)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N14 compound treatment 0.227 -0.0135 -0.72 -0.7229 -1.0 1089247 ChemDiv2_002412 OCC(O)C(O)C(O)c1cnn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N15 compound treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1667058 ChemDiv2_002413 CCOc1ccc(cc1OCC)C2CNC(=O)C2C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N16 compound treatment 0.226 -0.0145 -0.78 -0.7766 -1.0 1984588 ChemDiv2_002414 CC(=O)Nc1nonc1n2c(C)ccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N17 compound treatment 0.306 0.0655 3.52 3.5224 1.0 1573447 ChemDiv2_002415 CC1(C)CC(CCNC(=O)c2ccc(cc2)n3cnnn3)CC(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N18 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1984589 ChemDiv2_002416 CCOc1ccc(CC(=O)Nc2c(oc3ccc(Cl)cc23)C(=O)N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N19 compound treatment 0.229 -0.0115 -0.62 -0.6154 -1.0 1641065 ChemDiv2_002417 CCN(CC)C(=O)Cn1n(CC(=O)N(CC)CC)c(=O)n(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N20 compound treatment 0.221 -0.0195 -1.05 -1.0453 -1.0 1984590 ChemDiv2_002418 OC(CCN1CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N21 compound treatment 0.237 -0.00345 -0.19 -0.1855 -1.0 1688324 ChemDiv2_002419 Nc1nnnn1CC(=O)NC2(CCCCC2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N22 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1984591 ChemDiv2_002420 CC1(C)CCCC(C)(O1)C#CCN2CCCC(C2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N23 mock treatment 0.241 5.48E-4 0.03 0.0295 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 N24 mock treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O01 compound treatment 0.269 0.0285 1.53 1.5341 1.0 1605562 ChemDiv2_002421 COC(NC(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O02 compound treatment 0.251 0.0105 0.57 0.5668 1.0 1031015 ChemDiv2_002422 CC(C)Cn1cc(C)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O03 compound treatment 0.267 0.0265 1.43 1.4267 1.0 1984592 ChemDiv2_002423 CC(=O)NCCOc1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O04 compound treatment 0.247 0.00655 0.35 0.3519 1.0 1984593 ChemDiv2_002424 Cc1nnnn1CC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O05 compound treatment 0.231 -0.00945 -0.51 -0.5079 -1.0 1984594 ChemDiv2_002425 CCCOc1ccc(cc1)C(C)(N)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O06 compound treatment 0.266 0.0255 1.37 1.3729 1.0 1024170 ChemDiv2_002426 C(CN1CCN(CC1)c2ccccc2)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O07 compound treatment 0.379 0.139 7.45 7.4453 1.0 1538338 ChemDiv2_002427 CN(c1ccccc1)C2(O)C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O08 compound treatment 0.431 0.191 10.24 10.2397 1.0 1625180 ChemDiv2_002428 CS(=O)(=O)Nc1nnc(SCC(=O)Nc2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O09 compound treatment 0.268 0.0275 1.48 1.4804 1.0 1427934 ChemDiv2_002429 CCCN(Cc1ccccc1)C(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O10 compound treatment 0.248 0.00755 0.41 0.4056 1.0 1984595 ChemDiv2_002430 COCc1cc(C)c2c(N)c(C#N)sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O11 compound treatment 0.241 5.48E-4 0.03 0.0295 1.0 1118439 ChemDiv2_002431 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)n4cccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O12 compound treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1244047 ChemDiv2_002432 COc1ccc(CC(O)CN2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O13 compound treatment 0.25 0.00955 0.51 0.5131 1.0 1171455 ChemDiv2_002433 Nc1c2C(=O)NC(=O)Cc2nn1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O14 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1984596 ChemDiv2_002434 CCOC(=O)c1[nH]c2CCC/C(=N\O)/c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O15 compound treatment 0.301 0.0605 3.25 3.2537 1.0 1984597 ChemDiv2_002435 O=C(CSC1=NC(=O)C(C(=O)N1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O16 compound treatment 0.324 0.0835 4.49 4.4897 1.0 1223783 ChemDiv2_002436 Cc1nc(N)sc1Cc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O17 compound treatment 0.255 0.0145 0.78 0.7818 1.0 1951394 ChemDiv2_002437 O=C1c2ccccc2-c3c(sc(=O)n13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O18 compound treatment 0.548 0.308 16.53 16.527 1.0 1134714 ChemDiv2_002438 Nc1cc(ccc1F)c2nnn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O19 compound treatment 0.256 0.0155 0.84 0.8355 1.0 1146087 ChemDiv2_002439 Oc1c(Br)cc(CN2CCCCC2)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O20 compound treatment 0.242 0.00155 0.08 0.0832 1.0 1044244 ChemDiv2_002440 C(NCc1cccs1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O21 compound treatment 0.365 0.125 6.69 6.693 1.0 1984598 ChemDiv2_002441 CSc1nc(n[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O22 compound treatment 0.261 0.0205 1.1 1.1042 1.0 1244441 ChemDiv2_002442 O=C1N(CCc2nc[nH]n2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O23 mock treatment 0.252 0.0115 0.62 0.6206 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 O24 mock treatment 0.259 0.0185 1.0 0.9968 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P01 compound treatment 0.25 0.00955 0.51 0.5131 1.0 1210474 ChemDiv2_002443 OC(=O)C1CN(CCOc2ccccc2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P02 compound treatment 0.264 0.0235 1.27 1.2654 1.0 1545655 ChemDiv2_002444 Brc1ccc2oc(=O)c(cc2c1)c3cnc(CC#N)s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P03 compound treatment 0.258 0.0175 0.94 0.943 1.0 1147773 ChemDiv2_002445 CC1CCCCN1S(=O)(=O)c2ccc(CCN)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P04 compound treatment 0.246 0.00555 0.3 0.2982 1.0 1454113 ChemDiv2_002446 CCOc1ccc(cc1OCC)C(CN)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P05 compound treatment 0.38 0.14 7.5 7.499 1.0 1573519 ChemDiv2_002447 C=CCSc1nn2c(=O)c3ccccc3nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P06 compound treatment 0.23 -0.0105 -0.56 -0.5616 -1.0 1126477 ChemDiv2_002448 COc1ccc(NC(=O)C2(CCCCC2)N3C(CC3=O)c4ccc(OC(C)C)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P07 compound treatment 0.23 -0.0105 -0.56 -0.5616 -1.0 1634812 ChemDiv2_002449 CCOC(=O)c1ccc(CN)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P08 compound treatment 0.233 -0.00745 -0.4 -0.4004 -1.0 1984599 ChemDiv2_002450 CCOC1(OCC)N=C(N)C2(C#N)C1(C#N)C32CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P09 compound treatment 0.254 0.0135 0.73 0.7281 1.0 1386189 ChemDiv2_002451 CC1CN(Cc2ccccc2)CCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P10 compound treatment 0.231 -0.00945 -0.51 -0.5079 -1.0 1348666 ChemDiv2_002452 NC1(CCC1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P11 compound treatment 0.24 -4.52E-4 -0.02 -0.0243 -1.0 1255405 ChemDiv2_002453 COc1ccc(NC(=O)C2(CCCCC2)N(C)C(=O)c3ccc(cc3)n4cnnn4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P12 compound treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1446549 ChemDiv2_002454 CCN(Cc1c(C#N)c2ccccc2n1C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P13 compound treatment 0.26 0.0195 1.05 1.0505 1.0 1984600 ChemDiv2_002455 COC(=O)CSc1ccc(C#N)c(SCC(=O)OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P14 compound treatment 0.228 -0.0125 -0.67 -0.6691 -1.0 1984601 ChemDiv2_002456 OC(Cn1ccnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P15 compound treatment 0.23 -0.0105 -0.56 -0.5616 -1.0 3178 ChemDiv2_002457 CC(C)c1c(C)n(C)n(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P16 compound treatment 0.238 -0.00245 -0.13 -0.1317 -1.0 1984602 ChemDiv2_002458 NC#Cc1cnn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P17 compound treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1671387 ChemDiv2_002459 CN(C)CCn1c(C)cc(=O)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P18 compound treatment 0.278 0.0375 2.02 2.0178 1.0 1984603 ChemDiv2_002460 Clc1ccc(NC(=O)OC2CS(=O)(=O)CC2N3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P19 compound treatment 0.228 -0.0125 -0.67 -0.6691 -1.0 1432642 ChemDiv2_002461 CC(=O)OC1CC(N(C(C1c2ccccc2)c3ccccc3)C(=O)C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P20 compound treatment 0.225 -0.0155 -0.83 -0.8303 -1.0 1984604 ChemDiv2_002462 COc1ccc(cc1)C2Nc3nc4ccccc4n3C(=C2C(=O)Nc5ccccc5)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P21 compound treatment 0.233 -0.00745 -0.4 -0.4004 -1.0 1227021 ChemDiv2_002463 COc1ccc(NC(=O)C2(CCCCC2)N(Cc3ccccc3)C(=O)Cn4nnnc4N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P22 compound treatment 0.234 -0.00645 -0.35 -0.3467 -1.0 1984605 ChemDiv2_002464 CC1(C)CC(=O)C2=C(C1)C(c3cccnc3)c4c(N2)[nH]c(=O)[nH]c4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P23 mock treatment 0.229 -0.0115 -0.62 -0.6154 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1375 P24 mock treatment 0.236 -0.00445 -0.24 -0.2392 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A01 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984606 ChemDiv2_002465 CCOc1cc(NC(=O)c2ccco2)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A02 compound treatment 0.214 -0.00944 -0.51 -0.5072 -1.0 1984607 ChemDiv2_002466 CC(=O)OC(CN1CCCC1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A03 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984608 ChemDiv2_002467 COC(=O)c1oc2ccc(Br)cc2c1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A04 compound treatment 0.264 0.0406 2.18 2.1797 1.0 1984609 ChemDiv2_002468 Cc1cc([nH]n1)c2ccccc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A05 compound treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1984610 ChemDiv2_002469 CC(=O)OC(Cn1cccn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A06 compound treatment 0.433 0.21 11.26 11.2615 1.0 1984611 ChemDiv2_002470 CC1Cn2c(nnc2S1)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A07 compound treatment 0.218 -0.00544 -0.29 -0.2922 -1.0 1984612 ChemDiv2_002471 O=c1[nH]c(nc2n(Cc3ccccc3)c(=S)sc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A08 compound treatment 0.22 -0.00344 -0.18 -0.1847 -1.0 1984613 ChemDiv2_002472 COc1cc(nc2ccccc12)C(=O)NC3CCN(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A09 compound treatment 0.263 0.0396 2.13 2.126 1.0 1984614 ChemDiv2_002473 CNC(=O)CCC(=O)C1=C(CC(C)(C)CC1=O)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A10 compound treatment 0.231 0.00756 0.41 0.4064 1.0 1984615 ChemDiv2_002474 CC(=O)n1cc(C2OC(=O)C(C)(C)C(=O)C2(C)C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A11 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984616 ChemDiv2_002475 Cc1c(C)c2c(O)n(nc2[nH]c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A12 compound treatment 0.217 -0.00644 -0.35 -0.3459 -1.0 1984617 ChemDiv2_002476 Cc1c(c(=O)n(C)c(=O)n1C)S(=O)(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A13 compound treatment 0.226 0.00256 0.14 0.1377 1.0 1984618 ChemDiv2_002477 Cc1cc(c(C)s1)S(=O)(=O)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A14 compound treatment 0.234 0.0106 0.57 0.5676 1.0 1984619 ChemDiv2_002478 OC1(CCCCC1)C#CCN2CCCC[C@H]2c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A15 compound treatment 0.287 0.0636 3.42 3.4157 1.0 1984620 ChemDiv2_002479 Cc1nn(C(=O)c2ccoc2C)c(N)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A16 compound treatment 0.28 0.0566 3.04 3.0396 1.0 1984621 ChemDiv2_002480 CC(C)c1ccc2CC(C)(C)NC(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A17 compound treatment 0.24 0.0166 0.89 0.89 1.0 1984622 ChemDiv2_002481 CC(NC(=O)c1ccc(Cl)cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A18 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984623 ChemDiv2_002482 c1ccn(c1)c2nonc2c3nnc(o3)c4nonc4n5cccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A19 compound treatment 0.21 -0.0134 -0.72 -0.7221 -1.0 1984624 ChemDiv2_002483 CCOc1ccc2NC(C)(C)CC(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A20 compound treatment 0.213 -0.0104 -0.56 -0.5609 -1.0 1984625 ChemDiv2_002484 COc1ccc(F)cc1S(=O)(=O)NC(Cc2ccccc2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A21 compound treatment 0.273 0.0496 2.66 2.6634 1.0 1984626 ChemDiv2_002485 Nc1cccc(CCc2cccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A22 compound treatment 0.331 0.108 5.78 5.7802 1.0 1984627 ChemDiv2_002486 Fc1ccc(CSc2nsc(NC(=O)c3cccs3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A23 mock treatment 0.225 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 A24 mock treatment 0.231 0.00756 0.41 0.4064 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B01 compound treatment 0.252 0.0286 1.53 1.5349 1.0 1984628 ChemDiv2_002487 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B02 compound treatment 0.258 0.0346 1.86 1.8573 1.0 1984629 ChemDiv2_002488 CCC(C)(N(Cc1ccco1)C(=O)Cc2cccs2)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B03 compound treatment 0.262 0.0386 2.07 2.0723 1.0 1984630 ChemDiv2_002489 Cc1cc(Cc2ccccc2)c(C)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B04 compound treatment 0.262 0.0386 2.07 2.0723 1.0 1984631 ChemDiv2_002490 O=C(Cc1c[nH]c2ccccc12)NC3(CCCCC3)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B05 compound treatment 0.283 0.0596 3.2 3.2008 1.0 1984632 ChemDiv2_002491 CCOc1ccc(C)cc1n2nc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B06 compound treatment 0.291 0.0676 3.63 3.6307 1.0 1984633 ChemDiv2_002492 CC1CC(C(O)c2ccccn2)C(=O)C(C1)C(O)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B07 compound treatment 0.256 0.0326 1.75 1.7498 1.0 1984634 ChemDiv2_002493 O=C(Nc1ccc2OC3(CCCC3)Oc2c1)C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B08 compound treatment 0.262 0.0386 2.07 2.0723 1.0 1984635 ChemDiv2_002494 CC(C)C(NC(=O)C1CCCCC1)C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B09 compound treatment 0.257 0.0336 1.8 1.8036 1.0 1984636 ChemDiv2_002495 CN1C(=O)OC(C)(CCc2ccccc2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B10 compound treatment 0.252 0.0286 1.53 1.5349 1.0 1984637 ChemDiv2_002496 CCOc1ccccc1NC(=O)C(CC(C)C)NC(=O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B11 compound treatment 0.337 0.114 6.1 6.1026 1.0 1984638 ChemDiv2_002497 O=C1CC(C=C1Nc2ccccc2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B12 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1984639 ChemDiv2_002498 CC1CCC(CC1)C(=O)N2CCCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B13 compound treatment 0.341 0.118 6.32 6.3176 1.0 1984640 ChemDiv2_002499 COC(=O)Nc1ccc2C(=O)NC(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B14 compound treatment 0.469 0.246 13.2 13.196 1.0 1984641 ChemDiv2_002500 Clc1ccc2oc3c(=O)n(c4ccccc4)c(=O)[nH]c3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B15 compound treatment 0.233 0.00956 0.51 0.5139 1.0 1984642 ChemDiv2_002501 CCCCN(CC)C(=O)c1n[nH]c(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B16 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984643 ChemDiv2_002502 NC1=C(C#N)C(Nc2nc3ccccc3n12)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B17 compound treatment 0.413 0.19 10.19 10.1867 1.0 1984644 ChemDiv2_002503 CCN(CC)c1nc2cc(OC)ccc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B18 compound treatment 0.379 0.156 8.36 8.3596 1.0 1984645 ChemDiv2_002504 CSc1nc2CC(C)Sc2c(=O)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B19 compound treatment 0.324 0.101 5.4 5.404 1.0 1984646 ChemDiv2_002505 CN(C(C(=O)Nc1ccc2OCCOc2c1)c3ccc(C)cc3)C(=O)Cc4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B20 compound treatment 0.221 -0.00244 -0.13 -0.131 -1.0 1984647 ChemDiv2_002506 CCOC(=O)C1CCCC(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B21 compound treatment 0.263 0.0396 2.13 2.126 1.0 1984648 ChemDiv2_002507 COc1ccc(NC(=O)C(N(Cc2ccco2)C(=O)Cc3cccs3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B22 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984649 ChemDiv2_002508 Cc1ccc(N)cc1CN2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B23 mock treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 B24 mock treatment 0.209 -0.0144 -0.78 -0.7758 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C01 compound treatment 0.253 0.0296 1.59 1.5886 1.0 1984650 ChemDiv2_002509 Cc1cc(c(C)s1)S(=O)(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C02 compound treatment 0.244 0.0206 1.1 1.105 1.0 1984651 ChemDiv2_002510 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C03 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984652 ChemDiv2_002511 COC(=O)c1oc2ccc(OC)cc2c1NC(=O)CCCN3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C04 compound treatment 0.277 0.0536 2.88 2.8783 1.0 1984653 ChemDiv2_002512 COC(=O)Nc1ccc2ncn(C)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C05 compound treatment 0.252 0.0286 1.53 1.5349 1.0 1984654 ChemDiv2_002513 NC1=NC1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C06 compound treatment 0.251 0.0276 1.48 1.4812 1.0 1087592 ChemDiv2_002514 CCOc1ccc2nnnn2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C07 compound treatment 0.358 0.135 7.23 7.2311 1.0 1984655 ChemDiv2_002515 COc1ccc(cc1)c2nc3n(c4ccccc4)c(=S)sc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C08 compound treatment 0.269 0.0456 2.45 2.4484 1.0 1984656 ChemDiv2_002516 O=C1CCCC2=C1C(c3cccnc3)c4c(N2)ccc5ncccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C09 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1984657 ChemDiv2_002517 COc1ccc(cc1)C(=O)c2coc3ccc(O)c(CN4CCCCC4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C10 compound treatment 0.344 0.121 6.48 6.4788 1.0 1954071 ChemDiv2_002518 Nc1oc(c2ccco2)c(c1C#N)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C11 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984658 ChemDiv2_002519 Oc1n(nc2[nH]c(=O)cc(c3ccccc3)c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C12 compound treatment 0.24 0.0166 0.89 0.89 1.0 1984659 ChemDiv2_002520 COC(=O)C1C(CC(=CC1=O)Nc2ccc(F)cc2F)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C13 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1226878 ChemDiv2_002521 OCCOc1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C14 compound treatment 0.233 0.00956 0.51 0.5139 1.0 1984660 ChemDiv2_002522 Cn1c(=O)n(C)c2cc(CN3C(=O)OC(C)(C)C3(C)O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C15 compound treatment 0.365 0.142 7.61 7.6073 1.0 1984661 ChemDiv2_002523 COc1ccc(NC(=O)c2cccnc2Nc3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C16 compound treatment 0.24 0.0166 0.89 0.89 1.0 1984662 ChemDiv2_002524 COc1ccc(cc1OC)C2(CCCC2)C(=O)NC(C)(C)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C17 compound treatment 0.248 0.0246 1.32 1.3199 1.0 1984663 ChemDiv2_002525 CC(NC(=O)c1cccs1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C18 compound treatment 0.253 0.0296 1.59 1.5886 1.0 1984664 ChemDiv2_002526 Clc1ccccc1CS(=O)(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C19 compound treatment 0.298 0.0746 4.01 4.0068 1.0 1984665 ChemDiv2_002527 Nc1nc(C2CC2)c(Sc3sc(N)nc3C4CC4)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C20 compound treatment 0.379 0.156 8.36 8.3596 1.0 1984666 ChemDiv2_002528 O=C(NCCOc1ccc2ccccc2c1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C21 compound treatment 0.229 0.00556 0.3 0.2989 1.0 1984667 ChemDiv2_002529 CC1C(C)C(=O)CCN1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C22 compound treatment 0.232 0.00856 0.46 0.4601 1.0 1984668 ChemDiv2_002530 CC1C(C)N(Cc2ccccc2)CCC1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C23 mock treatment 0.229 0.00556 0.3 0.2989 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 C24 mock treatment 0.218 -0.00544 -0.29 -0.2922 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D01 compound treatment 0.26 0.0366 1.96 1.9648 1.0 1984669 ChemDiv2_002531 Cc1cc2ncn(C3CC(=O)N(C3=O)c4ccccc4Cl)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D02 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984670 ChemDiv2_002532 CCC(C)(N(Cc1cccs1)C(=O)c2ccccn2)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D03 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984671 ChemDiv2_002533 CC1C(C)C(=O)CCN1CCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D04 compound treatment 0.257 0.0336 1.8 1.8036 1.0 1984672 ChemDiv2_002534 CC(=O)N(c1ccc(C)cc1)C2(CCCCC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D05 compound treatment 0.28 0.0566 3.04 3.0396 1.0 1984673 ChemDiv2_002535 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)NCCOc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D06 compound treatment 0.248 0.0246 1.32 1.3199 1.0 1984674 ChemDiv2_002536 O=C1C(C(NC(C1c2ccccc2)c3cccnc3)c4cccnc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D07 compound treatment 0.256 0.0326 1.75 1.7498 1.0 1984675 ChemDiv2_002537 CCOc1ccc(cc1S(=O)(=O)NCc2ccccc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D08 compound treatment 0.269 0.0456 2.45 2.4484 1.0 1984676 ChemDiv2_002538 CC(C)C(NC(=O)C1CCCCC1)C(=O)Nc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D09 compound treatment 0.327 0.104 5.57 5.5652 1.0 1984677 ChemDiv2_002539 CSCCC1C(=C(N)Oc2[nH]nc(c3cccs3)c12)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D10 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984678 ChemDiv2_002540 O=C(CNC(=O)C1CCCCC1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D11 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984679 ChemDiv2_002541 CCCCC(C(=O)O)n1cccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D12 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984680 ChemDiv2_002542 CCCCC1CCC(CC1)C(=O)NC(C(C)C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D13 compound treatment 0.319 0.0956 5.14 5.1353 1.0 1984681 ChemDiv2_002543 Cn1c(CN2CCC(CC2)C(=O)N)c(C#N)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D14 compound treatment 0.312 0.0886 4.76 4.7592 1.0 1984682 ChemDiv2_002544 CCOC(=O)c1ccc(cc1)n2c(=S)sc3c(=O)[nH]c(C)nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D15 compound treatment 0.229 0.00556 0.3 0.2989 1.0 1984683 ChemDiv2_002545 COc1ccc(cc1)C2C(CCC(=O)N2c3ccc(OC)cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D16 compound treatment 0.471 0.248 13.3 13.3035 1.0 1984684 ChemDiv2_002546 O=C(Cc1ccc(cc1)n2c(=O)[nH]c3ccsc3c2=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D17 compound treatment 0.282 0.0586 3.15 3.147 1.0 1984685 ChemDiv2_002547 COc1ccc2cc(C#N)c(NC(C)C)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D18 compound treatment 0.393 0.17 9.11 9.1119 1.0 1984686 ChemDiv2_002548 CCSc1nc2CC(C)Sc2c(=O)n1CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D19 compound treatment 0.261 0.0376 2.02 2.0185 1.0 1984687 ChemDiv2_002549 CN(C(C(=O)Nc1ccc2OCCOc2c1)c3ccccc3)C(=O)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D20 compound treatment 0.218 -0.00544 -0.29 -0.2922 -1.0 1984688 ChemDiv2_002550 Cc1ccc2nsnc2c1N(S(=O)(=O)C)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D21 compound treatment 0.214 -0.00944 -0.51 -0.5072 -1.0 1984689 ChemDiv2_002551 CN(C(=O)Cc1cccs1)C2(CCCCC2)C(=O)Nc3c(C)cccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D22 compound treatment 0.428 0.205 10.99 10.9928 1.0 1984690 ChemDiv2_002552 Oc1nc2ccc(cc2nc1O)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D23 mock treatment 0.228 0.00456 0.25 0.2452 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 D24 mock treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E01 compound treatment 0.465 0.242 12.98 12.9811 1.0 1984691 ChemDiv2_002553 CCOC(=O)c1ccc(CNC(=O)CSc2nnnn2c3ccc(Cl)cc3)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E02 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984692 ChemDiv2_002554 Cc1nn(C(=O)c2cccc(Cl)c2)c(N)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E03 compound treatment 0.244 0.0206 1.1 1.105 1.0 1984693 ChemDiv2_002555 Fc1ccc(NC(=O)C2(CCOCC2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E04 compound treatment 0.546 0.323 17.33 17.3338 1.0 1984694 ChemDiv2_002556 Clc1ccc2oc(NS(=O)(=O)Cc3ccccc3Cl)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E05 compound treatment 0.53 0.307 16.47 16.474 1.0 1984695 ChemDiv2_002557 Oc1ccccc1c2nnc(COc3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E06 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984696 ChemDiv2_002558 Cc1nc2cccc(C(=O)NCc3ccccc3)c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E07 compound treatment 0.45 0.227 12.17 12.175 1.0 1984697 ChemDiv2_002559 Cc1cn(nc1O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E08 compound treatment 0.264 0.0406 2.18 2.1797 1.0 1984698 ChemDiv2_002560 Cc1ccc(Nc2nc(cs2)C3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E09 compound treatment 0.48 0.257 13.79 13.7871 1.0 1984699 ChemDiv2_002561 CC1Cn2c(nnc2S1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E10 compound treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1984700 ChemDiv2_002562 Cc1nccn1CCCN2C(=O)OC(C)(C)C2(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E11 compound treatment 0.368 0.145 7.77 7.7685 1.0 1984701 ChemDiv2_002563 Cc1nn(c2CCc3cnc(N)nc3-c12)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E12 compound treatment 0.379 0.156 8.36 8.3596 1.0 1984702 ChemDiv2_002564 O=C1CCCC(=C1)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E13 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984703 ChemDiv2_002565 CC(C)N(Cc1nccn1C)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E14 compound treatment 0.25 0.0266 1.43 1.4274 1.0 1984704 ChemDiv2_002566 Cc1ccc(OCCN2C(=O)OC(C)(C)C2(C)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E15 compound treatment 0.245 0.0216 1.16 1.1587 1.0 1984705 ChemDiv2_002567 COC(=O)CCC(=O)C1=C(N)CC(C)(C)CC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E16 compound treatment 0.236 0.0126 0.68 0.6751 1.0 1984706 ChemDiv2_002568 COc1ccc(cc1)C(=O)N[C@H]2COC(C)(C)O[C@H]2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E17 compound treatment 0.24 0.0166 0.89 0.89 1.0 1984707 ChemDiv2_002569 CC(NC(=O)c1cccnc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E18 compound treatment 0.398 0.175 9.38 9.3806 1.0 1984708 ChemDiv2_002570 Cn1c(=S)sc2c(=O)[nH]c(nc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E19 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1774296 ChemDiv2_002571 OC1CCN(C2CCCCC12)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E20 compound treatment 0.276 0.0526 2.82 2.8246 1.0 1984709 ChemDiv2_002572 Clc1ccc(CCNC(=O)C2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E21 compound treatment 0.227 0.00356 0.19 0.1914 1.0 1001259 ChemDiv2_002573 CC(C)(N)Cc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E22 compound treatment 0.224 5.62E-4 0.03 0.0302 1.0 1984710 ChemDiv2_002574 COCCN1CCC(OC(=O)C)C(C)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E23 mock treatment 0.237 0.0136 0.73 0.7288 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 E24 mock treatment 0.223 -4.38E-4 -0.02 -0.0235 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F01 compound treatment 0.395 0.172 9.22 9.2194 1.0 1984711 ChemDiv2_002575 COC(=O)c1ccc(COc2ccc(cc2)c3nnn(CC(=O)NC(C)(C)C)n3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F02 compound treatment 0.252 0.0286 1.53 1.5349 1.0 1984712 ChemDiv2_002576 CCC(C)(N(C(=O)C)c1ccccc1)C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F03 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1984713 ChemDiv2_002577 OC(=O)c1cccc(c1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F04 compound treatment 0.24 0.0166 0.89 0.89 1.0 1430912 ChemDiv2_002578 CN1CCc2c(C1)c3cc(C)ccc3n2CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F05 compound treatment 0.529 0.306 16.42 16.4203 1.0 1984714 ChemDiv2_002579 O=C1CCCN1c2ccc(cc2)S(=O)(=O)Nc3ccc(CC#N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F06 compound treatment 0.29 0.0666 3.58 3.5769 1.0 1984715 ChemDiv2_002580 CC(C)C(NC(=O)C1CCCCC1)C(=O)Nc2ccc(F)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F07 compound treatment 0.274 0.0506 2.72 2.7171 1.0 1984716 ChemDiv2_002581 CCOc1ccc(cc1S(=O)(=O)N2CCCCC2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F08 compound treatment 0.239 0.0156 0.84 0.8363 1.0 1984717 ChemDiv2_002582 CC(C)C(NC(=O)C1CCCCC1)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F09 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984718 ChemDiv2_002583 CCN(CC)C(=O)c1scc2OCCOc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F10 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1984719 ChemDiv2_002584 O=C(CNC(=O)C1CCCCC1)N2CCC(CC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F11 compound treatment 0.567 0.344 18.46 18.4623 1.0 1984720 ChemDiv2_002585 Cc1cc2COC(=O)c2c(SCC(=O)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F12 compound treatment 0.242 0.0186 1.0 0.9975 1.0 1984721 ChemDiv2_002586 O=C(c1ccccc1)c2c[nH]c3cc4OCOc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F13 compound treatment 0.233 0.00956 0.51 0.5139 1.0 1984722 ChemDiv2_002587 CCOC(=O)c1oc2ccccc2c1CN3CCC(CC3)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F14 compound treatment 0.316 0.0926 4.97 4.9741 1.0 1984723 ChemDiv2_002588 Cn1c(=O)c2sccc2n3c(CCCC(=O)NCc4ccc(F)cc4)nnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F15 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1774528 ChemDiv2_002589 OC(=O)Cc1n[nH]c(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F16 compound treatment 0.297 0.0736 3.95 3.9531 1.0 1984724 ChemDiv2_002590 O=S(=O)(c1cccs1)n2cccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F17 compound treatment 0.398 0.175 9.38 9.3806 1.0 1984725 ChemDiv2_002591 CN1C(=O)C2C=C(SC2c3ccccc13)C(=O)NCCN4CCC(Cc5ccccc5)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F18 compound treatment 0.495 0.272 14.59 14.5932 1.0 1984726 ChemDiv2_002592 CCSc1nc2CC(C)Sc2c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F19 compound treatment 0.24 0.0166 0.89 0.89 1.0 1984727 ChemDiv2_002593 CCC(C)(N(C(=O)C)c1ccc(cc1)C(=O)N)C(=O)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F20 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984728 ChemDiv2_002594 CS(=O)(=O)Nc1cccc2nsnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F21 compound treatment 0.217 -0.00644 -0.35 -0.3459 -1.0 1984729 ChemDiv2_002595 CCC(C)(N(Cc1ccco1)C(=O)c2ccccn2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F22 compound treatment 0.474 0.251 13.46 13.4647 1.0 1984730 ChemDiv2_002596 COc1ccc(cc1)c2cc3Sc4ccccc4Nc3nn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F23 mock treatment 0.22 -0.00344 -0.18 -0.1847 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 F24 mock treatment 0.217 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G01 compound treatment 0.242 0.0186 1.0 0.9975 1.0 1984731 ChemDiv2_002597 COc1cc(OC)cc(c1)C(=O)n2nc(C)c(c2N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G02 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984732 ChemDiv2_002598 CC1CCCCN1C(=O)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G03 compound treatment 0.236 0.0126 0.68 0.6751 1.0 1984733 ChemDiv2_002599 CN(C)c1nc(N)nc(n1)N(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G04 compound treatment 0.284 0.0606 3.25 3.2545 1.0 1984734 ChemDiv2_002600 O=C(Cc1cccc2ccccc12)Nc3cccc(c3)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G05 compound treatment 0.259 0.0356 1.91 1.9111 1.0 1984735 ChemDiv2_002601 OCC(CO)OC(CO)n1cnc2c(=O)[nH]c(NC(=O)c3ccccc3)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G06 compound treatment 0.25 0.0266 1.43 1.4274 1.0 1984736 ChemDiv2_002602 Cc1nc2cccc(C(=O)N3CCCCCC3)c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G07 compound treatment 0.268 0.0446 2.39 2.3947 1.0 1984737 ChemDiv2_002603 Cc1cc(C(=O)N2CCNCC2)c(o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G08 compound treatment 0.31 0.0866 4.65 4.6517 1.0 1984738 ChemDiv2_002604 Clc1ccc(Nc2nc(cs2)C3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G09 compound treatment 0.32 0.0966 5.19 5.1891 1.0 1984739 ChemDiv2_002605 COC(=O)COC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c3ccc(OC)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G10 compound treatment 0.28 0.0566 3.04 3.0396 1.0 1984740 ChemDiv2_002606 COc1nc([nH]c(=O)n1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G11 compound treatment 0.233 0.00956 0.51 0.5139 1.0 1984741 ChemDiv2_002607 Cc1nn(c2CCc3cnc(nc3-c12)c4ccc(Cl)cc4)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G12 compound treatment 0.282 0.0586 3.15 3.147 1.0 1984742 ChemDiv2_002608 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G13 compound treatment 0.239 0.0156 0.84 0.8363 1.0 1984743 ChemDiv2_002609 O=C(Cc1nnc[nH]1)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G14 compound treatment 0.242 0.0186 1.0 0.9975 1.0 1984744 ChemDiv2_002610 CCOc1ccc(CCNC(=O)C2CC(=CCC2C(=O)O)C)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G15 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984745 ChemDiv2_002611 CC(C)Oc1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G16 compound treatment 0.368 0.145 7.77 7.7685 1.0 1984746 ChemDiv2_002612 O=C1CC(CN1S(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G17 compound treatment 0.26 0.0366 1.96 1.9648 1.0 1984747 ChemDiv2_002613 COc1cccc(c1)N2C(=O)c3ccncc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G18 compound treatment 0.291 0.0676 3.63 3.6307 1.0 1984748 ChemDiv2_002614 CCc1nc(O)c2sc(=S)n(c3ccccc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G19 compound treatment 0.227 0.00356 0.19 0.1914 1.0 1984749 ChemDiv2_002615 CC(=O)N1CCC(O)C2CCCCC21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G20 compound treatment 0.258 0.0346 1.86 1.8573 1.0 1984750 ChemDiv2_002616 COC(=O)c1cc2ccccc2c(CN3C(=O)c4ccccc4C3=O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G21 compound treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1984751 ChemDiv2_002617 CCOC(=O)N1CCCC1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G22 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984752 ChemDiv2_002618 CC1C(C)N(CCc2ccccc2)CCC1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G23 mock treatment 0.232 0.00856 0.46 0.4601 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 G24 mock treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H01 compound treatment 0.518 0.295 15.83 15.8292 1.0 1984753 ChemDiv2_002619 Fc1ccc(cc1)c2nc3n(c4ccccc4)c(=S)sc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H02 compound treatment 0.258 0.0346 1.86 1.8573 1.0 1984754 ChemDiv2_002620 O=C(NC1CCCC1)C2(CCCCC2)N(Cc3ccco3)C(=O)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H03 compound treatment 0.248 0.0246 1.32 1.3199 1.0 1984755 ChemDiv2_002621 CC1(CCc2ccccc2)OC(=O)OC1=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H04 compound treatment 0.299 0.0756 4.06 4.0606 1.0 1984756 ChemDiv2_002622 Clc1cccc(CN2C(=O)CSc3ccc(cc23)C(=O)N4CCOCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H05 compound treatment 0.527 0.304 16.31 16.3128 1.0 1984757 ChemDiv2_002623 O=C1CCCN1c2ccc(cc2)S(=O)(=O)Nc3cccc(CCc4ccccn4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H06 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984758 ChemDiv2_002624 CCOC(=O)N1CCC(CC1)NC(=O)C(NC(=O)C2CCCCC2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H07 compound treatment 0.501 0.278 14.92 14.9156 1.0 1984759 ChemDiv2_002625 Ic1ccc(NS(=O)(=O)c2ccc(cc2)N3CCCC3=O)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H08 compound treatment 0.503 0.28 15.02 15.0231 1.0 1984760 ChemDiv2_002626 CC(C)C(NC(=O)C1CCCCC1)C(=O)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H09 compound treatment 0.239 0.0156 0.84 0.8363 1.0 1984761 ChemDiv2_002627 COc1nc(C)nc2n(C)c(=S)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H10 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1984762 ChemDiv2_002628 O=C(NC(Cc1ccccc1)C(=O)N2CCC3(CC2)OCCO3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H11 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1984763 ChemDiv2_002629 COC(=O)CSc1sc(=O)sc1SC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H12 compound treatment 0.259 0.0356 1.91 1.9111 1.0 1984764 ChemDiv2_002630 COC(=O)c1nnn(CC(=O)Nc2ccccc2)c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H13 compound treatment 0.304 0.0806 4.33 4.3293 1.0 1984765 ChemDiv2_002631 CCCn1nnc(NC(=O)Cc2ccc(Cl)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H14 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984766 ChemDiv2_002632 Cn1c(=O)c2sccc2n3c(CCCC(=O)NCc4ccc5OCOc5c4)nnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H15 compound treatment 0.432 0.209 11.21 11.2077 1.0 1984767 ChemDiv2_002633 CC1CCN(CC1)S(=O)(=O)c2ccc3ncn(CC(=O)N(C)Cc4ccccc4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H16 compound treatment 0.238 0.0146 0.78 0.7826 1.0 1984768 ChemDiv2_002634 Cc1c(CO)[nH]c2ccc(F)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H17 compound treatment 0.372 0.149 7.98 7.9834 1.0 1984769 ChemDiv2_002635 COc1ccc2cc3c(NCc4ccc(F)c(F)c4)n[nH]c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H18 compound treatment 0.399 0.176 9.43 9.4344 1.0 1984770 ChemDiv2_002636 CCOC(=O)c1nnc2ccnn2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H19 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984771 ChemDiv2_002637 CCC(C)(NC(=O)Cc1ccccc1)C(=O)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H20 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984772 ChemDiv2_002638 C=CCn1c(=O)n(CC=C)c2cc3[nH]nnc3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H21 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984773 ChemDiv2_002639 CCC(C)(N(Cc1cccs1)C(=O)C)C(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H22 compound treatment 0.319 0.0956 5.14 5.1353 1.0 1984774 ChemDiv2_002640 Cc1nc2nc(C)cc(SCC(=O)c3ccccc3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H23 mock treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 H24 mock treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I01 compound treatment 0.231 0.00756 0.41 0.4064 1.0 1046460 ChemDiv2_002641 OCc1nnn(c1CO)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I02 compound treatment 0.257 0.0336 1.8 1.8036 1.0 1786550 ChemDiv2_002642 Nc1ccccc1C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I03 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984775 ChemDiv2_002643 OC(Cn1cccn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I04 compound treatment 0.253 0.0296 1.59 1.5886 1.0 1984776 ChemDiv2_002644 CCc1nn(c2CCCC(=O)c12)c3cc(Cl)ccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I05 compound treatment 0.287 0.0636 3.42 3.4157 1.0 1984777 ChemDiv2_002645 C1CN(CCN1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I06 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984778 ChemDiv2_002646 CC(=O)Oc1c2c(C)n[nH]c2nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I07 compound treatment 0.351 0.128 6.85 6.8549 1.0 1984779 ChemDiv2_002647 O=C(NC1c2ccccc2-c3ccccc13)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I08 compound treatment 0.248 0.0246 1.32 1.3199 1.0 1984780 ChemDiv2_002648 Cc1ccc(N=c2scc3CCCn32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I09 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1984781 ChemDiv2_002649 C/C=C/C1(CC=C)CCCCN1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I10 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984782 ChemDiv2_002650 CCOC(=O)c1nnn(c1c2ccccc2)c3nc(nc(n3)N4CCCC4)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I11 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984783 ChemDiv2_002651 CC(C)(C)C(N)Cn1cccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I12 compound treatment 0.347 0.124 6.64 6.64 1.0 1984784 ChemDiv2_002652 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I13 compound treatment 0.236 0.0126 0.68 0.6751 1.0 1984785 ChemDiv2_002653 COc1cnc2n(C)c(=O)n(C)c(=O)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I14 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984786 ChemDiv2_002654 CC(=O)OC1(CCCCC1)C#CCN2CCCC[C@H]2c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I15 compound treatment 0.276 0.0526 2.82 2.8246 1.0 1984787 ChemDiv2_002655 COc1cc(NC(=O)c2cc(=O)n3c4ccccc4nc3s2)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I16 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984788 ChemDiv2_002656 O=c1n(c2ccccc2)c(=O)n3CCCn31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I17 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1260588 ChemDiv2_002657 Cn1cc(SCC(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I18 compound treatment 0.288 0.0646 3.47 3.4695 1.0 1984789 ChemDiv2_002658 COc1cc(ccc1OCC=C)c2nc3n(CC=C)c(=S)sc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I19 compound treatment 0.232 0.00856 0.46 0.4601 1.0 1984790 ChemDiv2_002659 CC1C(C)C(=O)CCN1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I20 compound treatment 0.225 0.00156 0.08 0.084 1.0 1984791 ChemDiv2_002660 NC(=O)C(Cc1ccccc1)NC(=O)Cc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I21 compound treatment 0.225 0.00156 0.08 0.084 1.0 1090165 ChemDiv2_002661 CNc1c(C)n(C)n(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I22 compound treatment 0.466 0.243 13.03 13.0348 1.0 1984792 ChemDiv2_002662 Cc1cc2COC(=O)c2c(SCc3ccccc3Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I23 mock treatment 0.232 0.00856 0.46 0.4601 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 I24 mock treatment 0.226 0.00256 0.14 0.1377 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J01 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1984793 ChemDiv2_002663 C(COc1nnnn1c2ccccc2)Oc3nnnn3c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J02 compound treatment 0.263 0.0396 2.13 2.126 1.0 1984794 ChemDiv2_002664 CC(=O)N(Cc1ccco1)C2(CCCCC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J03 compound treatment 0.24 0.0166 0.89 0.89 1.0 1984795 ChemDiv2_002665 OC(=O)CC(Cn1cnnn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J04 compound treatment 0.284 0.0606 3.25 3.2545 1.0 1984796 ChemDiv2_002666 Fc1ccccc1Cn2c(CSC3=NCCN3)nc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J05 compound treatment 0.545 0.322 17.28 17.2801 1.0 1984797 ChemDiv2_002667 Cn1cnnc1c2cccc(NS(=O)(=O)c3ccc(cc3)N4CCCC4=O)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J06 compound treatment 0.25 0.0266 1.43 1.4274 1.0 1984798 ChemDiv2_002668 CC(C)C(NC(=O)C1CCCCC1)C(=O)NC2CCCC(C)C2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J07 compound treatment 0.251 0.0276 1.48 1.4812 1.0 1984799 ChemDiv2_002669 COC(=O)Nc1ncc(CN2CCCC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J08 compound treatment 0.3 0.0766 4.11 4.1143 1.0 1984800 ChemDiv2_002670 CCOC(=O)c1cccc(NC(=O)C(CC(C)C)NC(=O)C2CCCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J09 compound treatment 0.244 0.0206 1.1 1.105 1.0 1984801 ChemDiv2_002671 Cc1ccc(NC(=O)CN2C(=O)OC(C)(C)C2(C)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J10 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1984802 ChemDiv2_002672 CCOc1ccc(NC(=O)C(Cc2ccccc2)NC(=O)C3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J11 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984803 ChemDiv2_002673 COc1cccc(c1)C2CC(=O)C=C(C2)NCCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J12 compound treatment 0.303 0.0796 4.28 4.2755 1.0 1984804 ChemDiv2_002674 Clc1ccc(cc1)C(=O)c2c[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J13 compound treatment 0.469 0.246 13.2 13.196 1.0 1984805 ChemDiv2_002675 CCOC(=O)c1n[nH]c(C(=O)c2ccc(Br)cc2)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J14 compound treatment 0.41 0.187 10.03 10.0255 1.0 1984806 ChemDiv2_002676 Cn1c(=O)c2sccc2n3c(CCCC(=O)NCCc4ccc(Cl)cc4)nnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J15 compound treatment 0.277 0.0536 2.88 2.8783 1.0 1984807 ChemDiv2_002677 CCOC(=O)Cn1ncc2c(=O)oc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J16 compound treatment 0.244 0.0206 1.1 1.105 1.0 1753974 ChemDiv2_002678 C1CN(CCO1)c2ccc(nn2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J17 compound treatment 0.41 0.187 10.03 10.0255 1.0 1984808 ChemDiv2_002679 CCOc1ccccc1N2CCN(CC2)S(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J18 compound treatment 0.267 0.0436 2.34 2.341 1.0 1984809 ChemDiv2_002680 COc1ccccc1NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J19 compound treatment 0.268 0.0446 2.39 2.3947 1.0 1984810 ChemDiv2_002681 CN(C(C(=O)Nc1ccc2OCCOc2c1)c3ccccc3)C(=O)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J20 compound treatment 0.218 -0.00544 -0.29 -0.2922 -1.0 1984811 ChemDiv2_002682 Cn1c(=O)n(C)c2cc(ccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J21 compound treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1984812 ChemDiv2_002683 CCC(C)(NC(=O)c1ccccn1)C(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J22 compound treatment 0.226 0.00256 0.14 0.1377 1.0 1984813 ChemDiv2_002684 N/C(=N/O)/c1nn(nc1N2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J23 mock treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 J24 mock treatment 0.215 -0.00844 -0.45 -0.4534 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K01 compound treatment 0.294 0.0706 3.79 3.7919 1.0 1984814 ChemDiv2_002685 CC1Cn2c(COc3ccccc3C)nnc2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K02 compound treatment 0.261 0.0376 2.02 2.0185 1.0 1984815 ChemDiv2_002686 CCCc1cc2OCOc2cc1NC(=O)c3ccccc3SC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K03 compound treatment 0.245 0.0216 1.16 1.1587 1.0 1984816 ChemDiv2_002687 C(NCc1ccc2OCOc2c1)C3NCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K04 compound treatment 0.275 0.0516 2.77 2.7709 1.0 1984817 ChemDiv2_002688 Oc1c(n[nH]c1C(=O)c2ccc(Br)cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K05 compound treatment 0.321 0.0976 5.24 5.2428 1.0 1984818 ChemDiv2_002689 c1cn(cn1)c2nc(nc(n2)n3ccnc3)N(c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K06 compound treatment 0.31 0.0866 4.65 4.6517 1.0 1984819 ChemDiv2_002690 CC(=O)n1c2ccccc2c3nc4ccccc4nc3oc5cc(C#N)c(C#N)cc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K07 compound treatment 0.373 0.15 8.04 8.0372 1.0 1984820 ChemDiv2_002691 CCOC(=O)c1ccc(CNC(=O)Cn2nnc(n2)c3ccc(C)cc3)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K08 compound treatment 0.242 0.0186 1.0 0.9975 1.0 1984821 ChemDiv2_002692 CN(c1ccccc1)c2nc(nc(n2)n3ccnc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K09 compound treatment 0.274 0.0506 2.72 2.7171 1.0 1286827 ChemDiv2_002693 Cc1[nH]c2ccc3n(CCC#N)cnc3c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K10 compound treatment 0.342 0.119 6.37 6.3713 1.0 1984822 ChemDiv2_002694 Cc1ccc(C)n1c2ccc3C(=O)OCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K11 compound treatment 0.286 0.0626 3.36 3.362 1.0 1984823 ChemDiv2_002695 Cc1ccc(cc1)N2C(=O)c3ccc(cc3C2=O)C(=O)NCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K12 compound treatment 0.357 0.134 7.18 7.1774 1.0 1984824 ChemDiv2_002696 CC1Cn2c(nnc2S1)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K13 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984825 ChemDiv2_002697 CCOc1cc(NC(=O)c2cccs2)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K14 compound treatment 0.296 0.0726 3.9 3.8994 1.0 1984826 ChemDiv2_002698 COc1ccc(NC(=O)c2cccnc2Nc3cccc(F)c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K15 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984827 ChemDiv2_002699 Cc1cc(=O)nc([nH]1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K16 compound treatment 0.253 0.0296 1.59 1.5886 1.0 1984828 ChemDiv2_002700 O=C(Nc1ccccc1)c2cccnc2N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K17 compound treatment 0.257 0.0336 1.8 1.8036 1.0 1658188 ChemDiv2_002701 OC(=O)CSc1cn(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K18 compound treatment 0.402 0.179 9.6 9.5956 1.0 1984829 ChemDiv2_002702 CCOc1ccc(CC(=O)C2=C(N)CC(C)(C)CC2=O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K19 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984830 ChemDiv2_002703 CC1C(C)C(=O)CCN1C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K20 compound treatment 0.28 0.0566 3.04 3.0396 1.0 1984831 ChemDiv2_002704 O=C(NCCOc1ccccc1Cc2ccccc2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K21 compound treatment 0.435 0.212 11.37 11.3689 1.0 1984832 ChemDiv2_002705 Nc1nc(SCc2ccc(Cl)cc2Cl)ns1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K22 compound treatment 0.226 0.00256 0.14 0.1377 1.0 1984833 ChemDiv2_002706 NC(=O)C1CCCN(CC#N)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K23 mock treatment 0.239 0.0156 0.84 0.8363 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 K24 mock treatment 0.228 0.00456 0.25 0.2452 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L01 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984834 ChemDiv2_002707 COc1ccc(cc1S(=O)(=O)N2CC(CC2=O)c3ccccc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L02 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1984835 ChemDiv2_002708 CC(=O)N(CC1CCCO1)C2(CCCCC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L03 compound treatment 0.251 0.0276 1.48 1.4812 1.0 1984836 ChemDiv2_002709 CCOC(=O)CN1C(C)CC(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L04 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1505303 ChemDiv2_002710 O=C1C(C(NC(C1c2ccccc2)c3ccco3)c4ccco4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L05 compound treatment 0.27 0.0466 2.5 2.5022 1.0 1984837 ChemDiv2_002711 CCN(CC)S(=O)(=O)c1ccc(cc1)C2CNC(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L06 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1984838 ChemDiv2_002712 COc1ccccc1CNC(=O)C(NC(=O)C2CCCCC2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L07 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984839 ChemDiv2_002713 CN(C)CCNS(=O)(=O)c1cc(C)sc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L08 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984840 ChemDiv2_002714 CC(C)CC(NC(=O)C1CCCCC1)C(=O)Nc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L09 compound treatment 0.258 0.0346 1.86 1.8573 1.0 1984841 ChemDiv2_002715 C(c1ccccc1)n2nnc3c(ncnc23)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L10 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984842 ChemDiv2_002716 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCCCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L11 compound treatment 0.297 0.0736 3.95 3.9531 1.0 1984843 ChemDiv2_002717 COc1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L12 compound treatment 0.449 0.226 12.12 12.1213 1.0 1984844 ChemDiv2_002718 Nc1c(nnn1c2ccccc2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L13 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984845 ChemDiv2_002719 CCOC(=O)c1nnn(c1CN2CCOCC2)c3nonc3n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L14 compound treatment 0.275 0.0516 2.77 2.7709 1.0 1984846 ChemDiv2_002720 COc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L15 compound treatment 0.373 0.15 8.04 8.0372 1.0 1984847 ChemDiv2_002721 Cc1ccc2[nH]c(=O)c3cc(sc3c2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L16 compound treatment 0.268 0.0446 2.39 2.3947 1.0 1984848 ChemDiv2_002722 Cc1c([nH]c2CC(CC(=O)c12)c3ccccc3Cl)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L17 compound treatment 0.433 0.21 11.26 11.2615 1.0 1984849 ChemDiv2_002723 COc1ccc(OC)c(c1)S(=O)(=O)N2CC(C)N(CC2C)S(=O)(=O)c3cc(OC)ccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L18 compound treatment 0.35 0.127 6.8 6.8012 1.0 1721509 ChemDiv2_002724 O=c1[nH]c(nc(c1C#N)c2ccccc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L19 compound treatment 0.303 0.0796 4.28 4.2755 1.0 1984850 ChemDiv2_002725 COc1ccc(NC(=O)C(N(C)C(=O)Cc2c[nH]c3ccccc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L20 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1244650 ChemDiv2_002726 OC(=O)CN1CC(CC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L21 compound treatment 0.206 -0.0174 -0.94 -0.9371 -1.0 1984851 ChemDiv2_002727 CCC(C)(NC(=O)C)C(=O)NC1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L22 compound treatment 0.227 0.00356 0.19 0.1914 1.0 1984852 ChemDiv2_002728 Fc1ccc(Cc2nnc(Cc3ccccc3)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L23 mock treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 L24 mock treatment 0.21 -0.0134 -0.72 -0.7221 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M01 compound treatment 0.384 0.161 8.63 8.6283 1.0 1984853 ChemDiv2_002729 Cn1nnnc1SCc2cc(=O)[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M02 compound treatment 0.268 0.0446 2.39 2.3947 1.0 1984854 ChemDiv2_002730 O=C(NCCc1ccccc1)c2ccccc2NS(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M03 compound treatment 0.486 0.263 14.11 14.1096 1.0 1984855 ChemDiv2_002731 COc1cccc(c1)c2nnc3SC(C)Cn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M04 compound treatment 0.256 0.0326 1.75 1.7498 1.0 1984856 ChemDiv2_002732 Nc1nc2CCCc2c(C(=O)OCCO)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M05 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984857 ChemDiv2_002733 CSC1=NC2(C)CCCCC2C31C=CC(=O)C=C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M06 compound treatment 0.5 0.277 14.86 14.8619 1.0 1984858 ChemDiv2_002734 COC(=O)c1ccc(COc2ccc(cc2)c3nnn[nH]3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M07 compound treatment 0.377 0.154 8.25 8.2521 1.0 1984859 ChemDiv2_002735 Cc1c(Br)c(=O)[nH]c(=O)n1COCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M08 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1984860 ChemDiv2_002736 COC(=O)COc1cccc2CC(C)(C)Oc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M09 compound treatment 0.242 0.0186 1.0 0.9975 1.0 1984861 ChemDiv2_002737 Cc1[nH]c2ccccc2c1C3CC(=O)NC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M10 compound treatment 0.28 0.0566 3.04 3.0396 1.0 1103851 ChemDiv2_002738 OC(=O)c1cccc(c1)c2nnn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M11 compound treatment 0.256 0.0326 1.75 1.7498 1.0 1984862 ChemDiv2_002739 CC1Oc2ccccc2CN(C1=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M12 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984863 ChemDiv2_002740 O=c1n(c2ccccc2)c(=O)n3CCCCn31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M13 compound treatment 0.264 0.0406 2.18 2.1797 1.0 1984864 ChemDiv2_002741 CCOc1cc(NC(=O)Cc2cccs2)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M14 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984865 ChemDiv2_002742 CN(C)Cc1cc(C)cc(c1O)C2(C)CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M15 compound treatment 0.309 0.0856 4.6 4.5979 1.0 1984866 ChemDiv2_002743 Cc1ncsc1CCSc2n[nH]c(=O)n2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M16 compound treatment 0.244 0.0206 1.1 1.105 1.0 1984867 ChemDiv2_002744 c1cn(cn1)c2ccc3nnnn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M17 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984868 ChemDiv2_002745 CC(C)n1ncc(C(=O)N)c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M18 compound treatment 0.544 0.321 17.23 17.2264 1.0 1984869 ChemDiv2_002746 CCn1c(=S)sc2c(=O)[nH]c(nc12)c3ccc(OC)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M19 compound treatment 0.231 0.00756 0.41 0.4064 1.0 1984870 ChemDiv2_002747 CC(C)N1CCC(=O)C(C)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M20 compound treatment 0.261 0.0376 2.02 2.0185 1.0 1984871 ChemDiv2_002748 NC(=O)C(Cc1ccccc1)NC(=O)c2ccccc2SCc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M21 compound treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1984872 ChemDiv2_002749 CC(C)(C)C(O)CN1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M22 compound treatment 0.226 0.00256 0.14 0.1377 1.0 1984873 ChemDiv2_002750 CCOc1cc(NC(=O)c2ccncc2)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M23 mock treatment 0.239 0.0156 0.84 0.8363 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 M24 mock treatment 0.222 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N01 compound treatment 0.272 0.0486 2.61 2.6096 1.0 1984874 ChemDiv2_002751 CCc1noc(N)c1C(=O)Nc2ccc(C)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N02 compound treatment 0.254 0.0306 1.64 1.6424 1.0 1984875 ChemDiv2_002752 CC(=O)N(Cc1cccs1)C2(CCCCC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N03 compound treatment 0.261 0.0376 2.02 2.0185 1.0 1984876 ChemDiv2_002753 CCOC(=O)c1c(c2cc(OC)ccc2OC)c3oc4ccccc4c3[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N04 compound treatment 0.263 0.0396 2.13 2.126 1.0 1984877 ChemDiv2_002754 CC1C(NC(C(C)C1=O)c2cccs2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N05 compound treatment 0.398 0.175 9.38 9.3806 1.0 1984878 ChemDiv2_002755 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N06 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984879 ChemDiv2_002756 CC1CCC(CC1)NC(=O)C(Cc2ccccc2)NC(=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N07 compound treatment 0.373 0.15 8.04 8.0372 1.0 1984880 ChemDiv2_002757 Cc1ccc(OCCn2cc(Br)c(=O)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N08 compound treatment 0.243 0.0196 1.05 1.0512 1.0 1984881 ChemDiv2_002758 COc1cc(NC(=O)C(CC(C)C)NC(=O)C2CCCCC2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N09 compound treatment 0.433 0.21 11.26 11.2615 1.0 1984882 ChemDiv2_002759 COc1cc(ccc1OCC=C)c2nc3n(C)c(=S)sc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N10 compound treatment 0.27 0.0466 2.5 2.5022 1.0 1984883 ChemDiv2_002760 COc1ccc(OC)c(NC(=O)C2CCCN2C(=O)C3CCC(C)CC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N11 compound treatment 0.232 0.00856 0.46 0.4601 1.0 1526814 ChemDiv2_002761 OC1CS(=O)(=O)CC1NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N12 compound treatment 0.267 0.0436 2.34 2.341 1.0 1984884 ChemDiv2_002762 Cc1ccc(CNc2c(cnn2Cc3ccc(C)cc3)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N13 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984885 ChemDiv2_002763 CC(C)c1cc(CN2CCN(CCC#N)CC2)cc(C(C)C)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N14 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1984886 ChemDiv2_002764 Cc1cc(C)cc(NC(=O)C/C(=N/O)/N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N15 compound treatment 0.255 0.0316 1.7 1.6961 1.0 1984887 ChemDiv2_002765 COc1ccc2[nH]c(=O)cc(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N16 compound treatment 0.221 -0.00244 -0.13 -0.131 -1.0 1984888 ChemDiv2_002766 COc1cc(OC)c2c(cc(nc2c1)c3ccc(O)c(OC)c3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N17 compound treatment 0.318 0.0946 5.08 5.0816 1.0 1984889 ChemDiv2_002767 O=C(Cc1cc2ccccc2[nH]1)NC(C(=O)Nc3ccc4OCOc4c3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N18 compound treatment 0.265 0.0416 2.23 2.2335 1.0 1984890 ChemDiv2_002768 CN(C)c1nccc(Nc2ccccc2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N19 compound treatment 0.239 0.0156 0.84 0.8363 1.0 1984891 ChemDiv2_002769 COc1ccc(NC(=O)C(NC(=O)Cc2cccs2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N20 compound treatment 0.228 0.00456 0.25 0.2452 1.0 1984892 ChemDiv2_002770 Cn1c(=O)n(C)c2cc(ccc12)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N21 compound treatment 0.223 -4.38E-4 -0.02 -0.0235 -1.0 1984893 ChemDiv2_002771 CCC(C)(N(C)C(=O)c1ccc2OCOc2c1)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N22 compound treatment 0.284 0.0606 3.25 3.2545 1.0 1984894 ChemDiv2_002772 Fc1ccc(Cc2nnc(o2)c3ccc(F)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N23 mock treatment 0.223 -4.38E-4 -0.02 -0.0235 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 N24 mock treatment 0.212 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O01 compound treatment 0.23 0.00656 0.35 0.3527 1.0 1984895 ChemDiv2_002773 COc1cc(OC)cc(c1)C(=O)NC(C)(C)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O02 compound treatment 0.261 0.0376 2.02 2.0185 1.0 1984896 ChemDiv2_002774 Brc1cncc(c1)C(=O)Nc2cccc(c2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O03 compound treatment 0.245 0.0216 1.16 1.1587 1.0 1984897 ChemDiv2_002775 CC(=O)OC(Cn1ccnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O04 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1984898 ChemDiv2_002776 CC(C)(C)C(=O)COC(=O)c1nonc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O05 compound treatment 0.448 0.225 12.07 12.0675 1.0 1984899 ChemDiv2_002777 Nc1nc(c(SC#N)s1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O06 compound treatment 0.253 0.0296 1.59 1.5886 1.0 1984900 ChemDiv2_002778 COc1ccccc1n2nnnc2SCC(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O07 compound treatment 0.297 0.0736 3.95 3.9531 1.0 1984901 ChemDiv2_002779 O=C(NCc1ccccn1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O08 compound treatment 0.241 0.0176 0.94 0.9438 1.0 1266074 ChemDiv2_002780 CC1(C)Cc2cccc(OCC(=O)O)c2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O09 compound treatment 0.326 0.103 5.51 5.5115 1.0 1984902 ChemDiv2_002781 COc1cccc(Oc2nnnn2c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O10 compound treatment 0.269 0.0456 2.45 2.4484 1.0 1984903 ChemDiv2_002782 CN1CCCc2cc(SC#N)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O11 compound treatment 0.258 0.0346 1.86 1.8573 1.0 1984904 ChemDiv2_002783 Cc1cc(c(C)s1)S(=O)(=O)NCc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O12 compound treatment 0.234 0.0106 0.57 0.5676 1.0 1984905 ChemDiv2_002784 Cc1ccc(c(O)c1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O13 compound treatment 0.342 0.119 6.37 6.3713 1.0 1984906 ChemDiv2_002785 Cc1nn(C(=O)c2cccs2)c(N)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O14 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984907 ChemDiv2_002786 CCOc1ccc(CC(=O)C2C(=O)CCCC2=O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O15 compound treatment 0.225 0.00156 0.08 0.084 1.0 1984908 ChemDiv2_002787 CN1CCC(CC1)NC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O16 compound treatment 0.242 0.0186 1.0 0.9975 1.0 1984909 ChemDiv2_002788 OC1(CCNC1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O17 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1475958 ChemDiv2_002789 OC(=O)c1cccnc1c2ncccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O18 compound treatment 0.357 0.134 7.18 7.1774 1.0 1984910 ChemDiv2_002790 CC(C)c1ccc(NC(=O)C2CC(=O)N(C(=S)S2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O19 compound treatment 0.229 0.00556 0.3 0.2989 1.0 1984911 ChemDiv2_002791 COCCN1CCC(=O)C(C)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O20 compound treatment 0.267 0.0436 2.34 2.341 1.0 1984912 ChemDiv2_002792 CC(C)Cc1ccc(cc1)C(C)C(=O)NC(Cc2ccccc2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O21 compound treatment 0.235 0.0116 0.62 0.6213 1.0 1984913 ChemDiv2_002793 NC(Cn1cccn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O22 compound treatment 0.217 -0.00644 -0.35 -0.3459 -1.0 1984914 ChemDiv2_002794 CCOc1cc(NC(=O)Cn2nnc3ccccc23)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O23 mock treatment 0.239 0.0156 0.84 0.8363 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 O24 mock treatment 0.219 -0.00444 -0.24 -0.2385 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P01 compound treatment 0.268 0.0446 2.39 2.3947 1.0 1984915 ChemDiv2_002795 Cc1ccc(C)c(c1)c2cc(C)ncc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P02 compound treatment 0.249 0.0256 1.37 1.3737 1.0 1984916 ChemDiv2_002796 O=C(Cc1cccs1)NC2(CCCCC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P03 compound treatment 0.286 0.0626 3.36 3.362 1.0 1984917 ChemDiv2_002797 CCS(=O)(=O)N1CCN(CC1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P04 compound treatment 0.388 0.165 8.84 8.8432 1.0 1984918 ChemDiv2_002798 OC(C1CCc2ccccc2C1=O)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P05 compound treatment 0.233 0.00956 0.51 0.5139 1.0 1984919 ChemDiv2_002799 CN(C1CCS(=O)(=O)C1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P06 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1984920 ChemDiv2_002800 CC(C)C(NC(=O)C1CCCCC1)C(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P07 compound treatment 0.294 0.0706 3.79 3.7919 1.0 1984921 ChemDiv2_002801 CC(C)(O)C#Cc1ccc(s1)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P08 compound treatment 0.238 0.0146 0.78 0.7826 1.0 1984922 ChemDiv2_002802 CC(C)CC(NC(=O)C1CCCCC1)C(=O)N2CCC3(CC2)OCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P09 compound treatment 0.276 0.0526 2.82 2.8246 1.0 1984923 ChemDiv2_002803 O=C(NC(=O)c1ccccc1)OCC2CCCN3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P10 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984924 ChemDiv2_002804 CC(C)C(NC(=O)C1CCC(C)CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P11 compound treatment 0.378 0.155 8.31 8.3059 1.0 1984925 ChemDiv2_002805 COc1ccc2C3=Nc4ccccc4SC3CCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P12 compound treatment 0.246 0.0226 1.21 1.2125 1.0 1984926 ChemDiv2_002806 COC(=O)c1ccc2c(=O)n3C4CS(=O)(=O)CC4Sc3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P13 compound treatment 0.237 0.0136 0.73 0.7288 1.0 1984927 ChemDiv2_002807 COC(=O)c1nnn(c1C)c2nc(nc(n2)N3CCCCC3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P14 compound treatment 0.536 0.313 16.8 16.7965 1.0 1984928 ChemDiv2_002808 Oc1ccc(Cl)cc1C2=Nc3ncnn3C(C2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P15 compound treatment 0.236 0.0126 0.68 0.6751 1.0 1984929 ChemDiv2_002809 COc1ccc2cc(C#N)c(Nc3cccc(F)c3)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P16 compound treatment 0.221 -0.00244 -0.13 -0.131 -1.0 1984930 ChemDiv2_002810 COC(=O)C1C(C)CC2=C(C(CC(=O)N2)c3ccccc3)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P17 compound treatment 0.252 0.0286 1.53 1.5349 1.0 1984931 ChemDiv2_002811 CN(C(C(=O)Nc1ccc2OCOc2c1)c3ccccc3)C(=O)Cc4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P18 compound treatment 0.214 -0.00944 -0.51 -0.5072 -1.0 1984932 ChemDiv2_002812 CC1CCCC(N1)C(=O)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P19 compound treatment 0.206 -0.0174 -0.94 -0.9371 -1.0 1984933 ChemDiv2_002813 COc1ccc(NC(=O)C(N(C)C(=O)Cc2cccs2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P20 compound treatment 0.247 0.0236 1.27 1.2662 1.0 1984934 ChemDiv2_002814 CNc1nn(nc1N)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P21 compound treatment 0.208 -0.0154 -0.83 -0.8296 -1.0 1984935 ChemDiv2_002815 CCC(C)(N(C(=O)c1ccccn1)c2ccccc2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P22 compound treatment 0.209 -0.0144 -0.78 -0.7758 -1.0 1984936 ChemDiv2_002816 N#Cc1nn(nc1N2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P23 mock treatment 0.212 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1376 P24 mock treatment 0.22 -0.00344 -0.18 -0.1847 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A01 compound treatment 0.303 0.0505 2.71 2.7121 1.0 1984937 ChemDiv2_002817 Clc1nc2ccc(cc2n3nnnc13)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A02 compound treatment 0.218 -0.0345 -1.86 -1.8556 -1.0 1984938 ChemDiv2_002818 COc1ccc(cc1Cl)N2C(=O)c3nccnc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A03 compound treatment 0.236 -0.0165 -0.89 -0.8884 -1.0 1984939 ChemDiv2_002819 Cc1cccc(NC(=O)C2NC(=O)CC2c3ccccc3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A04 compound treatment 0.265 0.0125 0.67 0.67 1.0 1984940 ChemDiv2_002820 CCOc1cc(cc(OCC)c1OCC)c2noc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A05 compound treatment 0.407 0.154 8.3 8.3008 1.0 1984941 ChemDiv2_002821 CCOC(=O)N1CCN(CC1)c2cnn(c3nc4ccccc4s3)c(=O)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A06 compound treatment 0.358 0.105 5.67 5.6677 1.0 1984942 ChemDiv2_002822 CCC(C)N(C)Cc1cccc(c1)C2(O)CCN(CC2)S(=O)(=O)c3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A07 compound treatment 0.49 0.237 12.76 12.7611 1.0 1360122 ChemDiv2_002823 CCOC(=O)CCCc1sc(N)nc1c2[nH]c(=O)[nH]c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A08 compound treatment 0.271 0.0185 0.99 0.9925 1.0 1984943 ChemDiv2_002824 Fc1ccc(cc1)C(=O)N=c2[nH]c3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A09 compound treatment 0.428 0.175 9.43 9.4293 1.0 1984944 ChemDiv2_002825 CCOC(=O)N1CCC(CC1)N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4ccc(OC)c(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A10 compound treatment 0.515 0.262 14.1 14.1045 1.0 1984945 ChemDiv2_002826 CC1CC(C)CN(C1)C(=O)CSc2nc3CCCc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A11 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1984946 ChemDiv2_002827 CCOC(=O)N1CCC(CC1)c2cc(O)n3nccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A12 compound treatment 0.32 0.0675 3.63 3.6256 1.0 1984947 ChemDiv2_002828 O=C(N1CCc2ccccc2C1)c3csc4CCCCc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A13 compound treatment 0.493 0.24 12.92 12.9223 1.0 1984948 ChemDiv2_002829 Fc1ccc(NC(=O)c2ccc3C(=O)N(Cc4ccco4)C(=O)c3c2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A14 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1984949 ChemDiv2_002830 CCOc1ccc(NC2CCN(CC2)C(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A15 compound treatment 0.229 -0.0235 -1.26 -1.2645 -1.0 1984950 ChemDiv2_002831 OC(=O)Cc1coc(n1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A16 compound treatment 0.25 -0.00253 -0.14 -0.136 -1.0 1984951 ChemDiv2_002832 CCOc1ccccc1CNC(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A17 compound treatment 0.456 0.203 10.93 10.934 1.0 1984952 ChemDiv2_002833 CCOC(=O)N1CCC(CC1)NCC2C(Oc3ccc(Cl)cc3)C(=O)N2c4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A18 compound treatment 0.29 0.0375 2.01 2.0135 1.0 1984953 ChemDiv2_002834 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A19 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1984954 ChemDiv2_002835 CCOC(=O)CCc1c(C)nc2ncnn2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A20 compound treatment 0.245 -0.00753 -0.4 -0.4047 -1.0 1984955 ChemDiv2_002836 COc1cccc(CNC(=O)c2[nH]c(C)c(C(=O)NC3CCCCC3)c2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A21 compound treatment 0.285 0.0325 1.74 1.7448 1.0 1984956 ChemDiv2_002837 COc1ccccc1C(=O)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A22 compound treatment 0.271 0.0185 0.99 0.9925 1.0 1984957 ChemDiv2_002838 Fc1ccc(cc1)c2cc3c(=O)[nH]ncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A23 mock treatment 0.273 0.0205 1.1 1.0999 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 A24 mock treatment 0.259 0.00647 0.35 0.3476 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B01 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1984958 ChemDiv2_002839 CCOC(=O)N1CCC2(CC1)CC(=O)c3c(O2)ccc4oc(C(=O)OCC)c(C)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B02 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1984959 ChemDiv2_002840 Cc1ccc(cc1N2CCCC2=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B03 compound treatment 0.278 0.0255 1.37 1.3686 1.0 1984960 ChemDiv2_002841 OC(=O)c1ccc(c2ccco2)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B04 compound treatment 0.604 0.351 18.89 18.8872 1.0 1984961 ChemDiv2_002842 CC1=Nc2cc(ccc2Sc3ccc(C)cc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B05 compound treatment 0.264 0.0115 0.62 0.6163 1.0 1984962 ChemDiv2_002843 CC(C(=O)O)n1nc(c2ccccc2)c3cc(Cl)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B06 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1984963 ChemDiv2_002844 OC(=O)Cn1nc(c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B07 compound treatment 0.534 0.281 15.13 15.1255 1.0 1984964 ChemDiv2_002845 CCc1nn(CCCC(=O)N2CCc3ccccc3C2)c(=O)c4cc5occc5n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B08 compound treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1984965 ChemDiv2_002846 CN1CCC(=CC1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B09 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1984966 ChemDiv2_002847 Nc1cccnc1N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B10 compound treatment 0.247 -0.00553 -0.3 -0.2972 -1.0 1984967 ChemDiv2_002848 OC(=O)Cn1cccc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B11 compound treatment 0.47 0.217 11.69 11.6863 1.0 1984968 ChemDiv2_002849 Clc1ccc(nn1)N2CCC=CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B12 compound treatment 0.289 0.0365 1.96 1.9598 1.0 1984969 ChemDiv2_002850 Cc1ccc(C)n1c2nnc(SCCCC(=O)O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B13 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1984970 ChemDiv2_002851 Cc1nc2cc(C)c(C)cc2n1CCCN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B14 compound treatment 0.275 0.0225 1.21 1.2074 1.0 1984971 ChemDiv2_002852 CCC(C)C(NCc1cccc(Br)c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B15 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1984972 ChemDiv2_002853 O=C(NC1CCCC1)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B16 compound treatment 0.244 -0.00853 -0.46 -0.4585 -1.0 1984973 ChemDiv2_002854 COc1ccc(CNCC2CCC(CC2)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B17 compound treatment 0.269 0.0165 0.88 0.885 1.0 1984974 ChemDiv2_002855 OC(=O)Cn1nc(cc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B18 compound treatment 0.268 0.0155 0.83 0.8313 1.0 1984975 ChemDiv2_002856 CC(=O)N1CCC2(CC1)CC(=O)c3cc(O)ccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B19 compound treatment 0.272 0.0195 1.05 1.0462 1.0 1260824 ChemDiv2_002857 CCC(Sc1nc2ccccc2c(=O)n1CCc3ccc(OC)c(OC)c3)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B20 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1984976 ChemDiv2_002858 Cc1ccc(C2=NCCNC2=O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B21 compound treatment 0.349 0.0965 5.18 5.184 1.0 1984977 ChemDiv2_002859 Cc1ccc2oc(nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B22 compound treatment 0.262 0.00947 0.51 0.5088 1.0 1984978 ChemDiv2_002860 O=c1ccc(n[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B23 mock treatment 0.259 0.00647 0.35 0.3476 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 B24 mock treatment 0.253 4.69E-4 0.03 0.0252 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C01 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1984979 ChemDiv2_002861 Cc1cc(C)n(n1)c2nc3cc(ccc3nc2Cl)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C02 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1984980 ChemDiv2_002862 CCOc1cc(cc(OCC)c1OCC)c2cc(N)n[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C03 compound treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1984981 ChemDiv2_002863 CC(C)(C)n1ncc(Cl)c(Cl)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C04 compound treatment 0.28 0.0275 1.48 1.4761 1.0 1984982 ChemDiv2_002864 Nc1onc(c1C#N)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C05 compound treatment 0.561 0.308 16.58 16.5765 1.0 1917726 ChemDiv2_002865 c1csc(c1)c2nnc(o2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C06 compound treatment 0.277 0.0245 1.31 1.3149 1.0 1984983 ChemDiv2_002866 CCC(C)N(C)Cc1cccc(c1)C2(O)CCN(CC2)S(=O)(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C07 compound treatment 0.238 -0.0145 -0.78 -0.7809 -1.0 1555086 ChemDiv2_002867 CC(C)(C)OC(=O)N1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C08 compound treatment 0.292 0.0395 2.12 2.121 1.0 1984984 ChemDiv2_002868 COc1ccc(cc1OC)C(=O)N=c2[nH]c3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C09 compound treatment 0.262 0.00947 0.51 0.5088 1.0 1984985 ChemDiv2_002869 CC(C)(C)OC(=O)N1CCC(CC1)c2cc(O)n(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C10 compound treatment 0.355 0.102 5.51 5.5065 1.0 1984986 ChemDiv2_002870 CCC(Sc1nc2CCCc2c(=O)[nH]1)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C11 compound treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1007333 ChemDiv2_002871 CN1CCN(CC(O)c2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C12 compound treatment 0.275 0.0225 1.21 1.2074 1.0 1984987 ChemDiv2_002872 CCCNC(=O)c1csc2CCCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C13 compound treatment 0.596 0.343 18.46 18.4573 1.0 1984988 ChemDiv2_002873 O=C(NCc1ccco1)c2ccc3C(=O)N(Cc4ccco4)C(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C14 compound treatment 0.252 -5.31E-4 -0.03 -0.0285 -1.0 1984989 ChemDiv2_002874 OC(=O)C1CCN(CC1)C(=O)c2ccccc2C(=O)N3CCC(CC3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C15 compound treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1984990 ChemDiv2_002875 COc1ccccc1CNc2ncccc2N3C(=O)CCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C16 compound treatment 0.266 0.0135 0.72 0.7238 1.0 1984991 ChemDiv2_002876 Brc1ccccc1CNC(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C17 compound treatment 0.279 0.0265 1.42 1.4224 1.0 1984992 ChemDiv2_002877 Cc1cccc(N2C(C(Oc3ccc(Cl)cc3Cl)C2=O)C(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C18 compound treatment 0.272 0.0195 1.05 1.0462 1.0 1984993 ChemDiv2_002878 CCc1n[nH]c(=O)c2cc3occc3n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C19 compound treatment 0.278 0.0255 1.37 1.3686 1.0 1984994 ChemDiv2_002879 Cc1nc2ncnn2c(C)c1CCC(=O)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C20 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1984995 ChemDiv2_002880 CC1CC(C)CN(CCCNC(=O)c2[nH]c(C)c(C(=O)NC3CCCCC3)c2C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C21 compound treatment 0.313 0.0605 3.25 3.2495 1.0 1223686 ChemDiv2_002881 CCOc1ccc(NC(=O)c2cccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C22 compound treatment 0.295 0.0425 2.28 2.2822 1.0 1096318 ChemDiv2_002882 N#Cc1ccccc1NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C23 mock treatment 0.265 0.0125 0.67 0.67 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 C24 mock treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D01 compound treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1984996 ChemDiv2_002883 Cc1nc2cc(ccc2n1C3CCCC3)S(=O)(=O)N4CCC(CC4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D02 compound treatment 0.259 0.00647 0.35 0.3476 1.0 1984997 ChemDiv2_002884 Cc1ccc(cc1)C(C#N)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D03 compound treatment 0.272 0.0195 1.05 1.0462 1.0 1984998 ChemDiv2_002885 CCOC(=O)Cn1nc2n(Cc3ccc(C)cc3)c4ccccc4n2c(=O)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D04 compound treatment 0.311 0.0585 3.14 3.142 1.0 1984999 ChemDiv2_002886 COC(=O)c1ccc(cc1O)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D05 compound treatment 0.243 -0.00953 -0.51 -0.5122 -1.0 1985000 ChemDiv2_002887 C(N1CCC(=CC1)c2c[nH]c3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D06 compound treatment 0.317 0.0645 3.46 3.4644 1.0 1985001 ChemDiv2_002888 OC(=O)CCCn1nc(c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D07 compound treatment 0.495 0.242 13.03 13.0298 1.0 1985002 ChemDiv2_002889 CCc1nn(CCCC(=O)NCc2ccc(OC)cc2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D08 compound treatment 0.474 0.221 11.9 11.9013 1.0 1985003 ChemDiv2_002890 CN(C1CCCCC1)c2nnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D09 compound treatment 0.25 -0.00253 -0.14 -0.136 -1.0 1470679 ChemDiv2_002891 CN(CC(=O)O)S(=O)(=O)c1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D10 compound treatment 0.355 0.102 5.51 5.5065 1.0 1985004 ChemDiv2_002892 OC(=O)C1CCN(CC1)c2ncnc3c2sc4cccc(F)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D11 compound treatment 0.532 0.279 15.02 15.0181 1.0 1985005 ChemDiv2_002893 O=c1c2ccccc2nc3ccc(nn13)N4CCCC5CCCCC54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D12 compound treatment 0.303 0.0505 2.71 2.7121 1.0 1985006 ChemDiv2_002894 COC(=O)c1sc2ccccc2c1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D13 compound treatment 0.455 0.202 10.88 10.8802 1.0 1985007 ChemDiv2_002895 CN(C1CCCCC1)c2ccc3nc4ccccc4c(=O)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D14 compound treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1985008 ChemDiv2_002896 CCC(C)C(NCc1cccc(C)c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D15 compound treatment 0.243 -0.00953 -0.51 -0.5122 -1.0 1985009 ChemDiv2_002897 CC(C)NC(=O)C1CCN(Cc2cnn(c2n3cccc3)c4ccccc4)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D16 compound treatment 0.332 0.0795 4.27 4.2705 1.0 1985010 ChemDiv2_002898 COC(=O)c1c[nH]n2c(NC3CCCCC3)c(nc12)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D17 compound treatment 0.443 0.19 10.24 10.2354 1.0 1647037 ChemDiv2_002899 OC(=O)c1cc2nc(cc(c3ccccc3)n2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D18 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1985011 ChemDiv2_002900 CC1CCCN(C1)S(=O)(=O)c2ccc3[nH]c(=O)cc(C(=O)O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D19 compound treatment 0.462 0.209 11.26 11.2564 1.0 1637309 ChemDiv2_002901 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCCC(=O)N4CCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D20 compound treatment 0.244 -0.00853 -0.46 -0.4585 -1.0 1985012 ChemDiv2_002902 CC1CCN(CC1)S(=O)(=O)N2CCC(CC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D21 compound treatment 0.291 0.0385 2.07 2.0672 1.0 1985013 ChemDiv2_002903 OC(=O)c1ccc2n(cnc2c1)C3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D22 compound treatment 0.289 0.0365 1.96 1.9598 1.0 1985014 ChemDiv2_002904 CCOC(=O)Cn1nc(ccc1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D23 mock treatment 0.265 0.0125 0.67 0.67 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 D24 mock treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E01 compound treatment 0.399 0.146 7.87 7.8709 1.0 1985015 ChemDiv2_002905 CCOC(=O)c1nnc(Cc2ccc(Cl)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E02 compound treatment 0.257 0.00447 0.24 0.2401 1.0 1075469 ChemDiv2_002906 Cc1ccn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E03 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1985016 ChemDiv2_002907 NC(=O)c1nnc(Cc2ccc(Cl)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E04 compound treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1985017 ChemDiv2_002908 O=c1[nH]c2cccnc2n1Cc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E05 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1087068 ChemDiv2_002909 Clc1cnn(c2ccccc2)c(=O)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E06 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985018 ChemDiv2_002910 Cc1[nH]c2ccccc2c1C3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E07 compound treatment 0.259 0.00647 0.35 0.3476 1.0 1985019 ChemDiv2_002911 CCOC(=O)CC(=O)C1CCN(CC1)C(=O)OC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E08 compound treatment 0.522 0.269 14.48 14.4807 1.0 1985020 ChemDiv2_002912 COc1ccc2cc3c(NC(=O)COc4cccc(C)c4)n[nH]c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E09 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1985021 ChemDiv2_002913 CCOC(=O)N1CCC(CC1)C(=O)/C(=N/O)/C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E10 compound treatment 0.316 0.0635 3.41 3.4107 1.0 1985022 ChemDiv2_002914 COc1ccc(CNC(=O)CN2C(=O)C(=C(c3ccc(C)cc3)S2(=O)=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E11 compound treatment 0.27 0.0175 0.94 0.9387 1.0 1985023 ChemDiv2_002915 CCOC(=O)c1[nH]cc(c1N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E12 compound treatment 0.274 0.0215 1.15 1.1537 1.0 1985024 ChemDiv2_002916 O=C(NCC1CCCO1)c2csc3CCCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E13 compound treatment 0.28 0.0275 1.48 1.4761 1.0 1985025 ChemDiv2_002917 CCC(=O)Nc1ccccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E14 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985026 ChemDiv2_002918 CC(C(=O)O)n1nc(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E15 compound treatment 0.331 0.0785 4.22 4.2167 1.0 1985027 ChemDiv2_002919 COc1ccccc1Cn2cnc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E16 compound treatment 0.284 0.0315 1.69 1.6911 1.0 1985028 ChemDiv2_002920 Brc1cccc(CNC(=O)Cc2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E17 compound treatment 0.336 0.0835 4.49 4.4854 1.0 1985029 ChemDiv2_002921 CCn1c(C)c(CCC(=O)O)c(=O)n2nc(cc12)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E18 compound treatment 0.446 0.193 10.4 10.3966 1.0 1985030 ChemDiv2_002922 CCOC(=O)CCCn1ncn2c3ccoc3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E19 compound treatment 0.345 0.0925 4.97 4.9691 1.0 1985031 ChemDiv2_002923 OCC(=O)c1ccc2cc[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E20 compound treatment 0.37 0.117 6.31 6.3125 1.0 1985032 ChemDiv2_002924 Clc1ccccc1CNC(=O)c2nsc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E21 compound treatment 0.261 0.00847 0.46 0.4551 1.0 1985033 ChemDiv2_002925 OC(=O)c1cccc2CN(Cc3cccnc3)C(=O)c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E22 compound treatment 0.294 0.0415 2.23 2.2284 1.0 1985034 ChemDiv2_002926 COC(=O)Cn1c2ccccc2c3nc(=O)cc(C)n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E23 mock treatment 0.266 0.0135 0.72 0.7238 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 E24 mock treatment 0.257 0.00447 0.24 0.2401 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F01 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985035 ChemDiv2_002927 Cc1nn2c(SCC(=O)O)cc(C)nc2c1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F02 compound treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1985036 ChemDiv2_002928 Cc1nc(N)[nH]c(=O)c1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F03 compound treatment 0.265 0.0125 0.67 0.67 1.0 1985037 ChemDiv2_002929 OC(=O)Cn1ncc2c3ccccc3n(Cc4ccc(Cl)cc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F04 compound treatment 0.381 0.128 6.9 6.9036 1.0 1985038 ChemDiv2_002930 COC(=O)c1ccc2S(=O)C(OC(=O)C)C(=O)N(Cc3ccc(C)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F05 compound treatment 0.3 0.0475 2.55 2.5509 1.0 1985039 ChemDiv2_002931 C1CC(=CCN1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F06 compound treatment 0.244 -0.00853 -0.46 -0.4585 -1.0 1985040 ChemDiv2_002932 Cc1ccc(/N=C\2/NC(=O)CC(S2)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F07 compound treatment 0.392 0.139 7.49 7.4948 1.0 1985041 ChemDiv2_002933 O=C(CCCn1ncn2c3ccoc3cc2c1=O)NC4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F08 compound treatment 0.498 0.245 13.19 13.191 1.0 1985042 ChemDiv2_002934 CN(Cc1ccccc1)c2nnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F09 compound treatment 0.238 -0.0145 -0.78 -0.7809 -1.0 1985043 ChemDiv2_002935 CC1CCCCN1Cc2ccc(cc2)c3nn[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F10 compound treatment 0.243 -0.00953 -0.51 -0.5122 -1.0 1985044 ChemDiv2_002936 COC(=O)Cn1cccc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F11 compound treatment 0.39 0.137 7.39 7.3873 1.0 1985045 ChemDiv2_002937 O=c1c2ccccc2nc3ccc(nn13)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F12 compound treatment 0.35 0.0975 5.24 5.2378 1.0 1985046 ChemDiv2_002938 Cc1ccccc1CSc2ncc(C#N)c(=N)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F13 compound treatment 0.402 0.149 8.03 8.0321 1.0 1985047 ChemDiv2_002939 COc1ccc(C(=O)CCC(=O)Nc2cccnc2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F14 compound treatment 0.239 -0.0135 -0.73 -0.7271 -1.0 1985048 ChemDiv2_002940 CCOc1ccc(CNC(CC(C)C)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F15 compound treatment 0.334 0.0815 4.38 4.378 1.0 1985049 ChemDiv2_002941 O=C(NCCc1ccccc1)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F16 compound treatment 0.586 0.333 17.92 17.9199 1.0 1985050 ChemDiv2_002942 OC(=O)c1ccc2Sc3ccccc3C(=N)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F17 compound treatment 0.339 0.0865 4.65 4.6466 1.0 1985051 ChemDiv2_002943 COc1ccc(NC(=O)c2sc(=S)n3c4ccsc4c(=O)[nH]c23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F18 compound treatment 0.448 0.195 10.5 10.5041 1.0 1985052 ChemDiv2_002944 CCOC(=O)C1CCN(CC1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F19 compound treatment 0.321 0.0685 3.68 3.6794 1.0 1985053 ChemDiv2_002945 CCC(Sc1nc2cc(OC)c(OC)cc2c(=O)n1Cc3ccco3)C(=O)Nc4ccccc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F20 compound treatment 0.261 0.00847 0.46 0.4551 1.0 1985054 ChemDiv2_002946 Fc1ccc(Cn2cccc2C#N)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F21 compound treatment 0.407 0.154 8.3 8.3008 1.0 1985055 ChemDiv2_002947 OC(=O)CNc1ccc(Cl)cc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F22 compound treatment 0.252 -5.31E-4 -0.03 -0.0285 -1.0 1985056 ChemDiv2_002948 OC(=O)Cn1nc(ccc1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F23 mock treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 F24 mock treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G01 compound treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1985057 ChemDiv2_002949 CC(C)n1nnc(CC(=O)N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G02 compound treatment 0.46 0.207 11.15 11.1489 1.0 1985058 ChemDiv2_002950 Nc1cc(no1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G03 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985059 ChemDiv2_002951 CCc1ccccc1NC(=O)C2NC(=O)CC2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G04 compound treatment 0.26 0.00747 0.4 0.4014 1.0 1985060 ChemDiv2_002952 Cc1ccc2[nH]c3C(CCCc3c2c1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G05 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985061 ChemDiv2_002953 COc1ccc(NC(=O)C(N(C(=O)C)c2ccc(C)cc2)c3ccccn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G06 compound treatment 0.299 0.0465 2.5 2.4971 1.0 1985062 ChemDiv2_002954 COc1ccc(cc1)c2cc3nc(C4CCN(CC4)C(=O)OC(C)(C)C)c(cn3n2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G07 compound treatment 0.236 -0.0165 -0.89 -0.8884 -1.0 1985063 ChemDiv2_002955 CCOC(=O)N1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G08 compound treatment 0.429 0.176 9.48 9.4831 1.0 1985064 ChemDiv2_002956 COC(=O)c1cc(NC(=O)CSCCc2ccccn2)cc(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G09 compound treatment 0.269 0.0165 0.88 0.885 1.0 1985065 ChemDiv2_002957 CCOC(=O)N1CCC(CC1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G10 compound treatment 0.346 0.0935 5.02 5.0228 1.0 1985066 ChemDiv2_002958 NS(=O)(=O)c1ccc(CCNC(=O)c2csc3CCCCc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G11 compound treatment 0.379 0.126 6.8 6.7962 1.0 1985067 ChemDiv2_002959 O=C(NCc1ccco1)c2cc(c(s2)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G12 compound treatment 0.299 0.0465 2.5 2.4971 1.0 1985068 ChemDiv2_002960 COC(=O)c1c(sc2CN(CCc12)C(=O)C)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G13 compound treatment 0.288 0.0355 1.91 1.906 1.0 1985069 ChemDiv2_002961 COc1ccccc1c2cc(N)[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G14 compound treatment 0.257 0.00447 0.24 0.2401 1.0 1985070 ChemDiv2_002962 Cc1nn(CC(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G15 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1985071 ChemDiv2_002963 Cc1nc2cc(nn2c(C)c1CC(=O)O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G16 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1985072 ChemDiv2_002964 CN(CC(=O)NCc1cccc(F)c1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G17 compound treatment 0.379 0.126 6.8 6.7962 1.0 1985073 ChemDiv2_002965 Cc1ccccc1N2C(CNCC3CCCO3)C(Oc4ccc(Cl)cc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G18 compound treatment 0.504 0.251 13.51 13.5134 1.0 1985074 ChemDiv2_002966 CCc1cc2c(cc3c(=O)[nH]nc(CC)n23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G19 compound treatment 0.323 0.0705 3.79 3.7868 1.0 1985075 ChemDiv2_002967 COc1ccc(NC(=O)CC2=C(CCC2=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G20 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1985076 ChemDiv2_002968 Cc1cc(C)c2N(CC(=O)O)C(=O)CSc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G21 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985077 ChemDiv2_002969 OC(=O)c1ncccc1C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G22 compound treatment 0.259 0.00647 0.35 0.3476 1.0 1985078 ChemDiv2_002970 COC(=O)Cn1ncn2cccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G23 mock treatment 0.255 0.00247 0.13 0.1327 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 G24 mock treatment 0.252 -5.31E-4 -0.03 -0.0285 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H01 compound treatment 0.265 0.0125 0.67 0.67 1.0 1985079 ChemDiv2_002971 OC(=O)c1c(sc2CCCc12)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H02 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985080 ChemDiv2_002972 CC(=O)N(C(=O)C)c1cc(ccc1Sc2ccc(Br)cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H03 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985081 ChemDiv2_002973 O=c1[nH]ncc2c3ccccc3n(Cc4ccccc4)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H04 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985082 ChemDiv2_002974 COC(=O)c1cnn2c(=O)c3CN(Cc4ccccc4)C(=O)c3[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H05 compound treatment 0.26 0.00747 0.4 0.4014 1.0 1985083 ChemDiv2_002975 CCC(C(=O)O)n1nc(c2ccccc2)c3cc(Cl)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H06 compound treatment 0.259 0.00647 0.35 0.3476 1.0 1985084 ChemDiv2_002976 Cc1cc(sc1C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H07 compound treatment 0.489 0.236 12.71 12.7073 1.0 1985085 ChemDiv2_002977 COc1ccc(CCNC(=O)CCCn2ncn3c4ccoc4cc3c2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H08 compound treatment 0.498 0.245 13.19 13.191 1.0 1985086 ChemDiv2_002978 Nc1nnc(s1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H09 compound treatment 0.234 -0.0185 -1.0 -0.9958 -1.0 1696165 ChemDiv2_002979 CC(C(=O)O)n1cnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H10 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985087 ChemDiv2_002980 OCc1cnn(c1n2cccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H11 compound treatment 0.379 0.126 6.8 6.7962 1.0 1985088 ChemDiv2_002981 O=c1c2ccccc2nc3ccc(NCc4cccs4)nn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H12 compound treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1985089 ChemDiv2_002982 NC(CSCc1cccc(Br)c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H13 compound treatment 0.387 0.134 7.23 7.2261 1.0 1985090 ChemDiv2_002983 Fc1ccc(cc1)C(=O)CCC(=O)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H14 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1985091 ChemDiv2_002984 Cc1c(NCc2ccccc2)cccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H15 compound treatment 0.295 0.0425 2.28 2.2822 1.0 1985092 ChemDiv2_002985 Cc1ccc(NC(=O)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H16 compound treatment 0.282 0.0295 1.58 1.5836 1.0 1985093 ChemDiv2_002986 Cc1ccccc1Cc2c(C)nc3ncnn3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H17 compound treatment 0.405 0.152 8.19 8.1934 1.0 1985094 ChemDiv2_002987 Fc1ccccc1Cn2c(=O)c3ccccc3n4nncc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H18 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985095 ChemDiv2_002988 OC(=O)C1CCN(CC1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H19 compound treatment 0.363 0.11 5.94 5.9364 1.0 1985096 ChemDiv2_002989 CCC(Sc1nc2cc(OC)c(OC)cc2c(=O)n1Cc3ccco3)C(=O)NCc4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H20 compound treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1985097 ChemDiv2_002990 NC(=O)c1cccn1Cc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H21 compound treatment 0.247 -0.00553 -0.3 -0.2972 -1.0 1671372 ChemDiv2_002991 OC(=O)CN(CC(=O)O)S(=O)(=O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H22 compound treatment 0.26 0.00747 0.4 0.4014 1.0 1985098 ChemDiv2_002992 Cc1ccc(cc1)c2ccc(=O)[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H23 mock treatment 0.255 0.00247 0.13 0.1327 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 H24 mock treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I01 compound treatment 0.233 -0.0195 -1.05 -1.0496 -1.0 1985099 ChemDiv2_002993 OC(=O)C1NC(=O)CC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I02 compound treatment 0.332 0.0795 4.27 4.2705 1.0 1985100 ChemDiv2_002994 COc1cccc(c1)c2noc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I03 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985101 ChemDiv2_002995 CCOc1ccc(NC(=O)C2NC(=O)CC2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I04 compound treatment 0.3 0.0475 2.55 2.5509 1.0 1985102 ChemDiv2_002996 CCOC(=O)N1CCN(CC1)C2CCCc3c2[nH]c4ccc(C)cc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I05 compound treatment 0.238 -0.0145 -0.78 -0.7809 -1.0 1985103 ChemDiv2_002997 Cn1cccc1C2=NCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I06 compound treatment 0.286 0.0335 1.8 1.7985 1.0 1985104 ChemDiv2_002998 COC(=O)c1cc(=O)n(CC=C)c(=NCC=C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I07 compound treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1985105 ChemDiv2_002999 CC(C)(C)OC(=O)N1CCC(CC1)c2cc(O)n[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I08 compound treatment 0.284 0.0315 1.69 1.6911 1.0 1985106 ChemDiv2_003000 COc1ccc(cc1OC)C2OC(=O)CC2C(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I09 compound treatment 0.273 0.0205 1.1 1.0999 1.0 1985107 ChemDiv2_003001 CCOC(=O)N1CCC(CC1)c2nc(C)sc2C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I10 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985108 ChemDiv2_003002 O=C(NCCN1CCOCC1)c2csc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I11 compound treatment 0.367 0.114 6.15 6.1513 1.0 1985109 ChemDiv2_003003 Cc1nc2cc(nn2c(C)c1CCC(=O)O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I12 compound treatment 0.244 -0.00853 -0.46 -0.4585 -1.0 1985110 ChemDiv2_003004 CC(=O)N1CCC(CC1)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I13 compound treatment 0.244 -0.00853 -0.46 -0.4585 -1.0 1985111 ChemDiv2_003005 Cc1nc2ncnn2c(C)c1CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I14 compound treatment 0.462 0.209 11.26 11.2564 1.0 1985112 ChemDiv2_003006 O=C(Nc1nnc(s1)N2CCCCCC2)c3csc4CCCCc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I15 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985113 ChemDiv2_003007 Cc1cc(N)n(n1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I16 compound treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1985114 ChemDiv2_003008 CN(CC(=O)NCc1ccccc1F)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I17 compound treatment 0.259 0.00647 0.35 0.3476 1.0 1985115 ChemDiv2_003009 CCOC(=O)N1CCC(CC1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I18 compound treatment 0.295 0.0425 2.28 2.2822 1.0 1985116 ChemDiv2_003010 CC(NC(=O)CSCc1cccs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I19 compound treatment 0.309 0.0565 3.03 3.0345 1.0 1985117 ChemDiv2_003011 CC(C)(C)OC(=O)N1CCC(CC1)c2c(cnn2c3ccccc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I20 compound treatment 0.443 0.19 10.24 10.2354 1.0 1985118 ChemDiv2_003012 OC(=O)CNc1nnc(s1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I21 compound treatment 0.257 0.00447 0.24 0.2401 1.0 1985119 ChemDiv2_003013 COC(=O)C(O)C(Sc1ccccc1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I22 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985120 ChemDiv2_003014 COc1cc(N)c(cc1OC)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I23 mock treatment 0.258 0.00547 0.29 0.2939 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 I24 mock treatment 0.254 0.00147 0.08 0.0789 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J01 compound treatment 0.311 0.0585 3.14 3.142 1.0 1985121 ChemDiv2_003015 Cc1n(Cc2ccccc2)c(C)c3c(=O)[nH]ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J02 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985122 ChemDiv2_003016 CC(=O)Nc1cc(ccc1Sc2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J03 compound treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1985123 ChemDiv2_003017 CCOC(=O)CN1CCOc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J04 compound treatment 0.264 0.0115 0.62 0.6163 1.0 1985124 ChemDiv2_003018 Clc1ccccc1c2cc(=O)[nH]c3CCCc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J05 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1985125 ChemDiv2_003019 CC(C(=O)O)n1c2ccccc2c3cn[nH]c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J06 compound treatment 0.534 0.281 15.13 15.1255 1.0 1985126 ChemDiv2_003020 CC1CCCC(C)N1c2nnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J07 compound treatment 0.277 0.0245 1.31 1.3149 1.0 1985127 ChemDiv2_003021 Fc1ccc(cc1)c2nc(CC(=O)NCc3ccccc3)co2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J08 compound treatment 0.416 0.163 8.78 8.7845 1.0 1985128 ChemDiv2_003022 CC(C)CN(CC(C)C)c1nnc(N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J09 compound treatment 0.464 0.211 11.36 11.3639 1.0 1985129 ChemDiv2_003023 Clc1ccc(nn1)N2CCCC3CCCCC32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J10 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985130 ChemDiv2_003024 ClCc1cnn(c1n2cccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J11 compound treatment 0.441 0.188 10.13 10.1279 1.0 1985131 ChemDiv2_003025 COc1ccc(CNc2ccc3nc4ccc(C)cc4c(=O)n3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J12 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1384775 ChemDiv2_003026 OC(=O)c1ccc(CNCc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J13 compound treatment 0.49 0.237 12.76 12.7611 1.0 1985132 ChemDiv2_003027 COc1ccc(CNC(=O)CCCn2ncc3ccc(C)cc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J14 compound treatment 0.407 0.154 8.3 8.3008 1.0 1985133 ChemDiv2_003028 CCOC(=O)Cc1ccc(NCc2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J15 compound treatment 0.263 0.0105 0.56 0.5626 1.0 1985134 ChemDiv2_003029 CCOC(=O)N1CCC(CC1)NC(=O)CCC(=O)N2CCOc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J16 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985135 ChemDiv2_003030 OC(=O)c1ccc(NCc2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J17 compound treatment 0.405 0.152 8.19 8.1934 1.0 1985136 ChemDiv2_003031 Cc1ccc(Cn2c(=O)c3ccccc3n4nncc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J18 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985137 ChemDiv2_003032 OC(=O)C1CCN(CC1)S(=O)(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J19 compound treatment 0.541 0.288 15.5 15.5017 1.0 1985138 ChemDiv2_003033 CN(C)C(=O)c1sc2nc(SCC(=O)NCc3ccco3)n(CCc4ccccc4)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J20 compound treatment 0.271 0.0185 0.99 0.9925 1.0 1985139 ChemDiv2_003034 Cc1ccc(C)c(Cn2cccc2C#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J21 compound treatment 0.375 0.122 6.58 6.5812 1.0 1985140 ChemDiv2_003035 OC(=O)CSc1ccc(nn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J22 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985141 ChemDiv2_003036 Cc1ccc(CS(=O)(=O)CCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J23 mock treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 J24 mock treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K01 compound treatment 0.238 -0.0145 -0.78 -0.7809 -1.0 1985142 ChemDiv2_003037 CC(NC(=O)Cc1nnn[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K02 compound treatment 0.302 0.0495 2.66 2.6583 1.0 1985143 ChemDiv2_003038 Cc1ccccc1c2noc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K03 compound treatment 0.509 0.256 13.78 13.7821 1.0 1985144 ChemDiv2_003039 Clc1cccc(Nc2cnn(c3nc4ccccc4s3)c(=O)c2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K04 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985145 ChemDiv2_003040 COc1cccc(c1)c2nn3c(C)cc(C)nc3c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K05 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985146 ChemDiv2_003041 Cn1cccc1C2=NC(C)(C)CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K06 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985147 ChemDiv2_003042 COC(=O)c1cc(=O)n(Cc2ccccc2)c(=NCc3ccccc3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K07 compound treatment 0.257 0.00447 0.24 0.2401 1.0 1985148 ChemDiv2_003043 CCOC(=O)N1CCC(CC1)c2[nH]nc(O)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K08 compound treatment 0.547 0.294 15.82 15.8241 1.0 1985149 ChemDiv2_003044 CNC(=O)c1ccc2Sc3c(C)ccc(C)c3C(=Nc2c1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K09 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985150 ChemDiv2_003045 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(ccc2CO)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K10 compound treatment 0.262 0.00947 0.51 0.5088 1.0 1985151 ChemDiv2_003046 O=C(NCCN1CCCCCC1)c2csc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K11 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985152 ChemDiv2_003047 OC(=O)c1cc(c(s1)N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K12 compound treatment 0.495 0.242 13.03 13.0298 1.0 1985153 ChemDiv2_003048 CCc1nnc(SCC(=O)OC)c2cc3sccc3n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K13 compound treatment 0.281 0.0285 1.53 1.5299 1.0 1985154 ChemDiv2_003049 COc1ccccc1Cn2c(=O)[nH]c3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K14 compound treatment 0.454 0.201 10.83 10.8265 1.0 1985155 ChemDiv2_003050 CC1CCCCN1c2nnc(NC(=O)c3csc4CCCCc34)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K15 compound treatment 0.288 0.0355 1.91 1.906 1.0 1985156 ChemDiv2_003051 CC(C)NCC1C(Oc2ccc(Cl)cc2)C(=O)N1c3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K16 compound treatment 0.268 0.0155 0.83 0.8313 1.0 1985157 ChemDiv2_003052 OC(=O)Cn1ncc2CCc3occc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K17 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985158 ChemDiv2_003053 O=C(NC1CCCCC1)C2N(Cc3ccc4OCOc4c3)C(=O)Cn5cccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K18 compound treatment 0.274 0.0215 1.15 1.1537 1.0 1985159 ChemDiv2_003054 O=C(CN1C(=O)c2ccccc2Sc3ccccc13)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K19 compound treatment 0.316 0.0635 3.41 3.4107 1.0 1985160 ChemDiv2_003055 OC(=O)c1ccc(C(=O)NCc2ccco2)c(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K20 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985161 ChemDiv2_003056 CC(N1C(=O)CSc2ncccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K21 compound treatment 0.272 0.0195 1.05 1.0462 1.0 1985162 ChemDiv2_003057 OC1C(Sc2ccccc2NC1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K22 compound treatment 0.252 -5.31E-4 -0.03 -0.0285 -1.0 1985163 ChemDiv2_003058 OC(=O)Cn1cc2CCCCCc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K23 mock treatment 0.257 0.00447 0.24 0.2401 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 K24 mock treatment 0.25 -0.00253 -0.14 -0.136 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L01 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985164 ChemDiv2_003059 Cc1[nH]c(C)c2c(=O)n(ncc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L02 compound treatment 0.243 -0.00953 -0.51 -0.5122 -1.0 1985165 ChemDiv2_003060 CCC(=O)Nc1cc(ccc1Sc2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L03 compound treatment 0.247 -0.00553 -0.3 -0.2972 -1.0 1985166 ChemDiv2_003061 Cc1cc(C)c(Cn2c3ccccc3c4cnn(CC(=O)O)c(=O)c24)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L04 compound treatment 0.274 0.0215 1.15 1.1537 1.0 1985167 ChemDiv2_003062 COc1ccc2oc(=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L05 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1985168 ChemDiv2_003063 CC1CCCCC1NCc2c(C)[nH]c(C)c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L06 compound treatment 0.455 0.202 10.88 10.8802 1.0 1985169 ChemDiv2_003064 CCC1=Nc2cc(ccc2Sc3ccccc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L07 compound treatment 0.247 -0.00553 -0.3 -0.2972 -1.0 1985170 ChemDiv2_003065 Fc1ccc(cc1)c2nc(CC(=O)N3CCOCC3)co2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L08 compound treatment 0.5 0.247 13.3 13.2985 1.0 1985171 ChemDiv2_003066 CC1CC(C)CN(C1)c2nnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L09 compound treatment 0.305 0.0525 2.82 2.8196 1.0 1985172 ChemDiv2_003067 CC1CN(CC(C)O1)c2ccc(Cl)nn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L10 compound treatment 0.247 -0.00553 -0.3 -0.2972 -1.0 1985173 ChemDiv2_003068 OC(=O)CSCc1cnn(c1n2cccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L11 compound treatment 0.328 0.0755 4.06 4.0555 1.0 1985174 ChemDiv2_003069 COc1ccc(cc1)c2noc(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L12 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1660940 ChemDiv2_003070 CCOC(=O)C1CCC(CNCc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L13 compound treatment 0.327 0.0745 4.0 4.0018 1.0 1985175 ChemDiv2_003071 Cc1ccc2cnn(CC(=O)N3CCc4ccccc4C3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L14 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985176 ChemDiv2_003072 CCOC(=O)CNCc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L15 compound treatment 0.459 0.206 11.1 11.0952 1.0 1985177 ChemDiv2_003073 CC1CC(C)CN(CCCNC(=O)C2CCCN(C2)c3nnc(s3)N4CCCC4=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L16 compound treatment 0.284 0.0315 1.69 1.6911 1.0 1074372 ChemDiv2_003074 CCOC(=O)CCCc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L17 compound treatment 0.345 0.0925 4.97 4.9691 1.0 1985178 ChemDiv2_003075 COc1ccccc1c2nnn3c2[nH]c(=O)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L18 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1177068 ChemDiv2_003076 CN(CC(=O)O)c1ccccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L19 compound treatment 0.46 0.207 11.15 11.1489 1.0 1648414 ChemDiv2_003077 CC1CCCCN1C(=O)c2ccc3C(=O)N(CCC4=CCCCC4)C(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L20 compound treatment 0.266 0.0135 0.72 0.7238 1.0 1033125 ChemDiv2_003078 NC(=O)CSc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L21 compound treatment 0.296 0.0435 2.34 2.3359 1.0 1985179 ChemDiv2_003079 CC1CCCCC1n2cnc3cc(ccc23)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L22 compound treatment 0.253 4.69E-4 0.03 0.0252 1.0 1985180 ChemDiv2_003080 OC(=O)CCS(=O)(=O)Cc1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L23 mock treatment 0.261 0.00847 0.46 0.4551 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 L24 mock treatment 0.245 -0.00753 -0.4 -0.4047 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M01 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985181 ChemDiv2_003081 COc1ccc2nc(Cl)c3nnnn3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M02 compound treatment 0.261 0.00847 0.46 0.4551 1.0 1985182 ChemDiv2_003082 COC(=O)c1c(N)onc1c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M03 compound treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1985183 ChemDiv2_003083 COc1ccc(CCNC(=O)C2NC(=O)CC2c3ccccc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M04 compound treatment 0.249 -0.00353 -0.19 -0.1898 -1.0 1985184 ChemDiv2_003084 COc1ccc(Cn2c(CCC(=O)O)nc3cccnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M05 compound treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1985185 ChemDiv2_003085 CCC1COC(=N1)c2cccn2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M06 compound treatment 0.287 0.0345 1.85 1.8523 1.0 1985186 ChemDiv2_003086 COC(=O)c1cc(=O)n(C2CC2)c(=NC3CC3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M07 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1985187 ChemDiv2_003087 Oc1cc([nH]n1)C2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M08 compound treatment 0.442 0.189 10.18 10.1817 1.0 1985188 ChemDiv2_003088 CCC(Sc1nc2CCCCc2c(=O)[nH]1)C(=O)Nc3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M09 compound treatment 0.376 0.123 6.63 6.635 1.0 1985189 ChemDiv2_003089 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(ccc2CO)C(=O)Nc3ccc(C)c(F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M10 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1985190 ChemDiv2_003090 CC1CCCC(C)N1CCCNC(=O)c2csc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M11 compound treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1003359 ChemDiv2_003091 Cc1ccccc1N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M12 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985191 ChemDiv2_003092 COC(=O)c1sccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M13 compound treatment 0.271 0.0185 0.99 0.9925 1.0 1985192 ChemDiv2_003093 COc1ccccc1Cn2c(=O)c(C)nc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M14 compound treatment 0.33 0.0775 4.16 4.163 1.0 1985193 ChemDiv2_003094 CCCOc1ccc(CNC(=O)Cc2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M15 compound treatment 0.53 0.277 14.91 14.9106 1.0 1985194 ChemDiv2_003095 CCOC(=O)CCc1c(C)n(CC)c2cc(nn2c1=O)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M16 compound treatment 0.273 0.0205 1.1 1.0999 1.0 1985195 ChemDiv2_003096 Cc1c(oc2CCc3cn[nH]c3-c12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M17 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1985196 ChemDiv2_003097 CC1CCC(CC1)NC(=O)C2N(C(=O)Cn3cccc23)c4cccc(F)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M18 compound treatment 0.287 0.0345 1.85 1.8523 1.0 1985197 ChemDiv2_003098 Clc1ccccc1NC(=O)C2CCN(Cc3cnn(c3n4cccc4)c5ccccc5)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M19 compound treatment 0.511 0.258 13.89 13.8896 1.0 1985198 ChemDiv2_003099 CCOC(=O)c1nc([nH]c1C)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M20 compound treatment 0.333 0.0805 4.32 4.3242 1.0 1985199 ChemDiv2_003100 COc1ccc(cc1)c2cc3c(=O)[nH]ncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M21 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985200 ChemDiv2_003101 OCc1nccnc1C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M22 compound treatment 0.267 0.0145 0.78 0.7775 1.0 1985201 ChemDiv2_003102 COc1cc2[nH]n3c(C)cc(=O)nc3c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M23 mock treatment 0.252 -5.31E-4 -0.03 -0.0285 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 M24 mock treatment 0.256 0.00347 0.19 0.1864 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N01 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1985202 ChemDiv2_003103 Cc1n(Cc2ccccc2)c(C)c3c(=O)n(CC(=O)O)ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N02 compound treatment 0.25 -0.00253 -0.14 -0.136 -1.0 1985203 ChemDiv2_003104 OC(=O)c1ccc(CS(=O)c2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N03 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1985204 ChemDiv2_003105 COC(=O)Cn1ncc2c3ccccc3n(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N04 compound treatment 0.251 -0.00153 -0.08 -0.0823 -1.0 1985205 ChemDiv2_003106 COc1ccccc1c2cc(=O)[nH]c3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N05 compound treatment 0.342 0.0895 4.81 4.8079 1.0 1985206 ChemDiv2_003107 CCOc1ccc(CCNCc2c(C)[nH]c(C)c2C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N06 compound treatment 0.334 0.0815 4.38 4.378 1.0 1044815 ChemDiv2_003108 O=C(c1ccc[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N07 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1985207 ChemDiv2_003109 CS(=O)(=O)n1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N08 compound treatment 0.569 0.316 17.01 17.0064 1.0 1985208 ChemDiv2_003110 Nc1nnc(s1)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N09 compound treatment 0.302 0.0495 2.66 2.6583 1.0 1985209 ChemDiv2_003111 Clc1ccc2nc3ccc(nn3c(=O)c2c1)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N10 compound treatment 0.5 0.247 13.3 13.2985 1.0 1985210 ChemDiv2_003112 CCOC(=O)COc1ccc2OC3(CCCCC3)CC(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N11 compound treatment 0.37 0.117 6.31 6.3125 1.0 1985211 ChemDiv2_003113 O=c1c2ccccc2nc3ccc(NCc4ccco4)nn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N12 compound treatment 0.365 0.112 6.04 6.0438 1.0 1594192 ChemDiv2_003114 OC(=O)c1ccccc1NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N13 compound treatment 0.26 0.00747 0.4 0.4014 1.0 1985212 ChemDiv2_003115 Cc1ccc2cnn(CC(=O)N3CCCCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N14 compound treatment 0.254 0.00147 0.08 0.0789 1.0 1985213 ChemDiv2_003116 OC(=O)C1CCC(CNCc2cccc(Br)c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N15 compound treatment 0.369 0.116 6.26 6.2588 1.0 1985214 ChemDiv2_003117 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2cc(C(=O)OCC)n(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N16 compound treatment 0.266 0.0135 0.72 0.7238 1.0 1985215 ChemDiv2_003118 OC(=O)CCC1CC(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N17 compound treatment 0.278 0.0255 1.37 1.3686 1.0 1985216 ChemDiv2_003119 O=c1[nH]c2c(nnn2c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N18 compound treatment 0.27 0.0175 0.94 0.9387 1.0 1985217 ChemDiv2_003120 CC(C)N1C(CCC1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N19 compound treatment 0.435 0.182 9.81 9.8055 1.0 1449954 ChemDiv2_003121 CC1CCCN(C1)C(=O)c2ccc3C(=O)N(CCC4=CCCCC4)C(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N20 compound treatment 0.407 0.154 8.3 8.3008 1.0 1985218 ChemDiv2_003122 OC(=O)COc1ccc2OC3(CCCCC3)CC(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N21 compound treatment 0.305 0.0525 2.82 2.8196 1.0 1985219 ChemDiv2_003123 CCOC(=O)c1ccc(CS(=O)(=O)c2ccc(Cl)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N22 compound treatment 0.264 0.0115 0.62 0.6163 1.0 1985220 ChemDiv2_003124 OC(=O)c1cccn1Cc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N23 mock treatment 0.247 -0.00553 -0.3 -0.2972 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 N24 mock treatment 0.241 -0.0115 -0.62 -0.6197 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O01 compound treatment 0.226 -0.0265 -1.43 -1.4257 -1.0 1985221 ChemDiv2_003125 OC(=O)Cc1nnn(n1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O02 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1985222 ChemDiv2_003126 CCOc1cc(cc(OCC)c1OCC)c2noc(N)c2C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O03 compound treatment 0.245 -0.00753 -0.4 -0.4047 -1.0 1418235 ChemDiv2_003127 OC(=O)c1ccc(cc1)n2ncc(Cl)c(Cl)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O04 compound treatment 0.269 0.0165 0.88 0.885 1.0 1985223 ChemDiv2_003128 CCOC(=O)Cn1c(=O)n(Cc2ccco2)c3ncccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O05 compound treatment 0.301 0.0485 2.6 2.6046 1.0 1985224 ChemDiv2_003129 Cc1ccc(cc1N2CCCC2=O)C(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O06 compound treatment 0.329 0.0765 4.11 4.1093 1.0 1985225 ChemDiv2_003130 Fc1ccccc1C(=O)N=c2[nH]c3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O07 compound treatment 0.26 0.00747 0.4 0.4014 1.0 1985226 ChemDiv2_003131 CCOC(=O)N1CCC(CC1)c2cc(O)n(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O08 compound treatment 0.384 0.131 7.06 7.0649 1.0 1985227 ChemDiv2_003132 COC(=O)c1ccccc1NC(=O)CSc2nc3CCCCc3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O09 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1361195 ChemDiv2_003133 CCOC(=O)N1CCC(CC1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O10 compound treatment 0.271 0.0185 0.99 0.9925 1.0 1985228 ChemDiv2_003134 CC1CCCC(C)N1C(=O)c2csc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O11 compound treatment 0.27 0.0175 0.94 0.9387 1.0 1985229 ChemDiv2_003135 O=C1N(C(=O)c2ccccc12)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O12 compound treatment 0.255 0.00247 0.13 0.1327 1.0 1985230 ChemDiv2_003136 OC(=O)CN1C(=O)c2cccnc2Sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O13 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1985231 ChemDiv2_003137 CCOC(=O)CN1Cc2cccc(C(=O)O)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O14 compound treatment 0.261 0.00847 0.46 0.4551 1.0 1985232 ChemDiv2_003138 Cc1ccccc1CNC(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O15 compound treatment 0.264 0.0115 0.62 0.6163 1.0 1985233 ChemDiv2_003139 Cc1nn(c2nc(C)c(CCC(=O)O)c(C)c12)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O16 compound treatment 0.503 0.25 13.46 13.4597 1.0 1985234 ChemDiv2_003140 CCOC(=O)CCCn1nc(C)n2c3ccsc3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O17 compound treatment 0.271 0.0185 0.99 0.9925 1.0 1985235 ChemDiv2_003141 CC1CCCCC1NC(=O)C2N(Cc3ccccc3)C(=O)Cn4cccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O18 compound treatment 0.262 0.00947 0.51 0.5088 1.0 1985236 ChemDiv2_003142 Cc1[nH]c(C(=O)N2CCCCC2)c(C)c1C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O19 compound treatment 0.268 0.0155 0.83 0.8313 1.0 1985237 ChemDiv2_003143 OC1N(Cc2ccccc2)C(=O)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O20 compound treatment 0.515 0.262 14.1 14.1045 1.0 1985238 ChemDiv2_003144 CCOC(=O)C1CCN(CC1)c2nnc(s2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O21 compound treatment 0.258 0.00547 0.29 0.2939 1.0 1985239 ChemDiv2_003145 OC(=O)c1ncccc1C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O22 compound treatment 0.28 0.0275 1.48 1.4761 1.0 1985240 ChemDiv2_003146 CCOC(=O)N1CCC2(CC1)CC(=O)c3cc(O)ccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O23 mock treatment 0.258 0.00547 0.29 0.2939 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 O24 mock treatment 0.242 -0.0105 -0.57 -0.5659 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P01 compound treatment 0.238 -0.0145 -0.78 -0.7809 -1.0 1985241 ChemDiv2_003147 Cc1cc(C(=O)O)c(C)n1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P02 compound treatment 0.231 -0.0215 -1.16 -1.157 -1.0 1985242 ChemDiv2_003148 COC(=O)c1ccc(CS(=O)(=O)c2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P03 compound treatment 0.23 -0.0225 -1.21 -1.2108 -1.0 1985243 ChemDiv2_003149 COC(=O)Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P04 compound treatment 0.225 -0.0275 -1.48 -1.4795 -1.0 1985244 ChemDiv2_003150 CC(C)(C)NC(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P05 compound treatment 0.239 -0.0135 -0.73 -0.7271 -1.0 1985245 ChemDiv2_003151 CC1CCC(CC1)NCc2c(C)n(Cc3ccccc3)c(C)c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P06 compound treatment 0.235 -0.0175 -0.94 -0.9421 -1.0 1985246 ChemDiv2_003152 OC(=O)c1cc2CS(=O)(=O)Cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P07 compound treatment 0.287 0.0345 1.85 1.8523 1.0 1417078 ChemDiv2_003153 C(c1ccco1)n2c(nc3ccccc23)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P08 compound treatment 0.261 0.00847 0.46 0.4551 1.0 1985247 ChemDiv2_003154 OC(=O)c1cnn(c1n2cccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P09 compound treatment 0.411 0.158 8.52 8.5158 1.0 1985248 ChemDiv2_003155 Clc1ccc(NCC2CCCCC2)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P10 compound treatment 0.298 0.0455 2.44 2.4434 1.0 1985249 ChemDiv2_003156 Cc1cc(C)c2c(c(sc2n1)C(=O)O)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P11 compound treatment 0.427 0.174 9.38 9.3756 1.0 1985250 ChemDiv2_003157 O=c1c2ccccc2nc3ccc(NC4CCCCC4)nn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P12 compound treatment 0.229 -0.0235 -1.26 -1.2645 -1.0 1985251 ChemDiv2_003158 CC(C)C(NCc1c(Cl)cccc1Cl)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P13 compound treatment 0.236 -0.0165 -0.89 -0.8884 -1.0 1985252 ChemDiv2_003159 Cc1ccc2cnn(CC(=O)NCc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P14 compound treatment 0.234 -0.0185 -1.0 -0.9958 -1.0 1985253 ChemDiv2_003160 Cc1ccccc1CNCC2CCC(CC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P15 compound treatment 0.232 -0.0205 -1.1 -1.1033 -1.0 1985254 ChemDiv2_003161 Cc1cc(C)n(CC(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P16 compound treatment 0.256 0.00347 0.19 0.1864 1.0 1985255 ChemDiv2_003162 COC(=O)c1cc(O)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P17 compound treatment 0.276 0.0235 1.26 1.2612 1.0 1985256 ChemDiv2_003163 COc1ccc(cc1)c2nnn3c2[nH]c(=O)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P18 compound treatment 0.24 -0.0125 -0.67 -0.6734 -1.0 1985257 ChemDiv2_003164 CCOC(=O)CN1C(=O)CSc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P19 compound treatment 0.323 0.0705 3.79 3.7868 1.0 1497865 ChemDiv2_003165 CCc1cc2c(C)cc(=O)oc2c3C(=O)COc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P20 compound treatment 0.232 -0.0205 -1.1 -1.1033 -1.0 1985258 ChemDiv2_003166 CC1CC(C)CC(C1)S(=O)(=O)N2CCC(CC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P21 compound treatment 0.248 -0.00453 -0.24 -0.2435 -1.0 1985259 ChemDiv2_003167 Cc1ccc(cc1)S(=O)(=O)NCC(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P22 compound treatment 0.238 -0.0145 -0.78 -0.7809 -1.0 1985260 ChemDiv2_003168 CC(=O)n1cccc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P23 mock treatment 0.246 -0.00653 -0.35 -0.351 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1377 P24 mock treatment 0.243 -0.00953 -0.51 -0.5122 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A01 compound treatment 0.264 0.018 0.97 0.9673 1.0 1279784 ChemDiv2_003169 COc1ccc(cc1)c2ccc(=O)[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A02 compound treatment 0.294 0.048 2.58 2.5794 1.0 1985261 ChemDiv2_003170 CCC(C)NC(=O)c1coc2nc3ccccc3nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A03 compound treatment 0.255 0.009 0.48 0.4836 1.0 1985262 ChemDiv2_003171 CCn1cc(C2=NCC(C)O2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A04 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1985263 ChemDiv2_003172 COC(=O)c1sccc1N2C(C(=O)NC3CCC(C)CC3)c4cccn4CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A05 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1985264 ChemDiv2_003173 C1OC(=NC1c2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A06 compound treatment 0.222 -0.024 -1.29 -1.2897 -1.0 1985265 ChemDiv2_003174 OC(=O)CCSc1nnc(c2cccnc2)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A07 compound treatment 0.269 0.023 1.24 1.236 1.0 1985266 ChemDiv2_003175 CCc1nn2c(cc(=O)nc2s1)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A08 compound treatment 0.424 0.178 9.57 9.5653 1.0 1985267 ChemDiv2_003176 COC(=O)CS(=O)(=O)c1cc(Br)cc2CCN(C(=O)C)c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A09 compound treatment 0.224 -0.022 -1.18 -1.1822 -1.0 1626292 ChemDiv2_003177 Cc1ccccc1CS(=O)(=O)CC2Nc3cc(ccc3NC2=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A10 compound treatment 0.227 -0.019 -1.02 -1.021 -1.0 1985268 ChemDiv2_003178 COC(=O)c1ccc(cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A11 compound treatment 0.213 -0.033 -1.77 -1.7734 -1.0 1985269 ChemDiv2_003179 CC(C)(N1C(=O)c2ccccc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A12 compound treatment 0.349 0.103 5.54 5.535 1.0 1985270 ChemDiv2_003180 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A13 compound treatment 0.395 0.149 8.01 8.0069 1.0 1985271 ChemDiv2_003181 CCOc1ccccc1CNC(=O)CCSCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A14 compound treatment 0.234 -0.012 -0.64 -0.6449 -1.0 1985272 ChemDiv2_003182 OC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A15 compound treatment 0.231 -0.015 -0.81 -0.8061 -1.0 1985273 ChemDiv2_003183 CC1CCCC(NC(=O)CNC(=O)c2cccs2)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A16 compound treatment 0.233 -0.013 -0.7 -0.6986 -1.0 1392007 ChemDiv2_003184 COc1ccc(cc1)n2nc(C(=O)N3CCCc4ccccc34)c5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A17 compound treatment 0.315 0.069 3.71 3.7079 1.0 1985274 ChemDiv2_003185 Clc1ccc(CSCCC(=O)NC2CCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A18 compound treatment 0.293 0.047 2.53 2.5257 1.0 1985275 ChemDiv2_003186 COc1cc(cc(Br)c1OCc2ccccn2)C3NC(Cc4nc[nH]c34)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A19 compound treatment 0.277 0.031 1.67 1.6659 1.0 1985276 ChemDiv2_003187 Fc1ccc(CSCC(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A20 compound treatment 0.254 0.008 0.43 0.4299 1.0 1391920 ChemDiv2_003188 CN(C)c1ccc(CNCc2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A21 compound treatment 0.259 0.013 0.7 0.6986 1.0 1985277 ChemDiv2_003189 Brc1ccc2[nH]c(=O)cc(C(=O)N3CCC4(CC3)OCCO4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A22 compound treatment 0.407 0.161 8.65 8.6518 1.0 1985278 ChemDiv2_003190 COc1ccc2-c3[nH]nc(C(=O)O)c3CCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A23 mock treatment 0.259 0.013 0.7 0.6986 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 A24 mock treatment 0.257 0.011 0.59 0.5911 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B01 compound treatment 0.206 -0.04 -2.15 -2.1495 -1.0 1985279 ChemDiv2_003191 C1CNCC(C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B02 compound treatment 0.291 0.045 2.42 2.4182 1.0 1408148 ChemDiv2_003192 Nc1ccc2C(=O)N(CCO)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B03 compound treatment 0.224 -0.022 -1.18 -1.1822 -1.0 1985280 ChemDiv2_003193 CCC1CCCCN1CCCN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B04 compound treatment 0.25 0.004 0.21 0.215 1.0 1985281 ChemDiv2_003194 CCC(=O)Nc1cc(on1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B05 compound treatment 0.231 -0.015 -0.81 -0.8061 -1.0 1985282 ChemDiv2_003195 OC(=O)C1(CCCCC1)NCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B06 compound treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1494617 ChemDiv2_003196 Cc1cc(C)nc(SCCN2CCCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B07 compound treatment 0.224 -0.022 -1.18 -1.1822 -1.0 1985283 ChemDiv2_003197 Cc1ccc(CSCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B08 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1739095 ChemDiv2_003198 O=c1[nH]n(c2ncnc3sc4CCCCc4c23)c(=O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B09 compound treatment 0.252 0.006 0.32 0.3224 1.0 1985284 ChemDiv2_003199 CCOc1ccc2OC3(CCCC3)CC(SCC(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B10 compound treatment 0.261 0.015 0.81 0.8061 1.0 1313411 ChemDiv2_003200 O=C(Nc1c(nc2ncccn12)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B11 compound treatment 0.235 -0.011 -0.59 -0.5911 -1.0 1985285 ChemDiv2_003201 Nc1ccc(CN2CCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B12 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1464209 ChemDiv2_003202 COC(=O)C1=C(C)NC2=C(C1c3cc4OCOc4cc3Br)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B13 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1326545 ChemDiv2_003203 CC(=C)C(C)(O)C#CCN1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B14 compound treatment 0.252 0.006 0.32 0.3224 1.0 1779182 ChemDiv2_003204 CC(C)OC(=O)CNc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B15 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1915647 ChemDiv2_003205 Nc1c(cnn1c2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B16 compound treatment 0.253 0.007 0.38 0.3762 1.0 1383023 ChemDiv2_003206 Cn1c(=N)n(CC(=O)C(C)(C)C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B17 compound treatment 0.481 0.235 12.63 12.6284 1.0 1160479 ChemDiv2_003207 Oc1cccc(NC(=O)c2cccc(c2)S(=O)(=O)Nc3cccc(O)c3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B18 compound treatment 0.273 0.027 1.45 1.4509 1.0 1709235 ChemDiv2_003208 CN(C)CCCN1C(SCC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B19 compound treatment 0.456 0.21 11.28 11.285 1.0 1730812 ChemDiv2_003209 Oc1ccc2[nH]cc(CCN3C(=O)c4ccccc4C3=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B20 compound treatment 0.258 0.012 0.64 0.6449 1.0 1317969 ChemDiv2_003210 CC(=O)Nc1ccc2NC(C3CC=CC3c2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B21 compound treatment 0.261 0.015 0.81 0.8061 1.0 1241622 ChemDiv2_003211 COC(=O)c1ccc(cc1)c2ncc(o2)c3ccc(cc3)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B22 compound treatment 0.255 0.009 0.48 0.4836 1.0 1464945 ChemDiv2_003212 Oc1ccc(NC(=O)c2ccccc2)cc1c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B23 mock treatment 0.242 -0.004 -0.21 -0.215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 B24 mock treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C01 compound treatment 0.229 -0.017 -0.91 -0.9135 -1.0 1985286 ChemDiv2_003213 CCOc1ccc2OC(C)(C)CC(NCCN3CCOCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C02 compound treatment 0.391 0.145 7.79 7.792 1.0 1985287 ChemDiv2_003214 CC1CCN(CCCNC(=O)c2coc3nc4ccccc4nc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C03 compound treatment 0.287 0.041 2.2 2.2033 1.0 1985288 ChemDiv2_003215 O=C(NC1CC1)C2CSC(=N2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C04 compound treatment 0.226 -0.02 -1.07 -1.0748 -1.0 1985289 ChemDiv2_003216 COc1ccc(C)cc1N2C(C(=O)NC3CCC(C)CC3)c4cccn4CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C05 compound treatment 0.231 -0.015 -0.81 -0.8061 -1.0 1985290 ChemDiv2_003217 OC(=O)C1CSC(=N1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C06 compound treatment 0.388 0.142 7.63 7.6308 1.0 1985291 ChemDiv2_003218 COc1c(N)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C07 compound treatment 0.331 0.085 4.57 4.5677 1.0 1985292 ChemDiv2_003219 COC(=O)c1cc(=O)[nH]c(SCc2cccc(C)c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C08 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1985293 ChemDiv2_003220 Cc1cc(C)c([nH]1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C09 compound treatment 0.227 -0.019 -1.02 -1.021 -1.0 1985294 ChemDiv2_003221 OC(=O)CCS(=O)(=O)Cc1ccccc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C10 compound treatment 0.217 -0.029 -1.56 -1.5584 -1.0 1985295 ChemDiv2_003222 Cc1ccc(CNC(=O)Cc2ccc(cc2)n3cccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C11 compound treatment 0.229 -0.017 -0.91 -0.9135 -1.0 1985296 ChemDiv2_003223 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)NC3CCCCC3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C12 compound treatment 0.228 -0.018 -0.97 -0.9673 -1.0 1985297 ChemDiv2_003224 CC1CCCCN1S(=O)(=O)c2ccc3n(CC(=O)O)c(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C13 compound treatment 0.536 0.29 15.58 15.584 1.0 1985298 ChemDiv2_003225 O=C(CCC1CC(=O)Nc2ccccc12)NCCC3=CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C14 compound treatment 0.261 0.015 0.81 0.8061 1.0 1985299 ChemDiv2_003226 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)NCCN(C)C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C15 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1985300 ChemDiv2_003227 CCOC(=O)N1CCC(CC1)NC(=O)CNC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C16 compound treatment 0.25 0.004 0.21 0.215 1.0 1398317 ChemDiv2_003228 CCOc1ccccc1N(C)C(=O)c2nn(c3ccc(OC)cc3OC)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C17 compound treatment 0.365 0.119 6.39 6.3948 1.0 1985301 ChemDiv2_003229 Clc1ccc(CSCCC(=O)NCc2cccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C18 compound treatment 0.251 0.005 0.27 0.2687 1.0 1985302 ChemDiv2_003230 COc1ccccc1C/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C19 compound treatment 0.331 0.085 4.57 4.5677 1.0 1985303 ChemDiv2_003231 Cc1ccc(CCNC(=O)CSCc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C20 compound treatment 0.267 0.021 1.13 1.1285 1.0 1025810 ChemDiv2_003232 Nc1ccc(OCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C21 compound treatment 0.256 0.01 0.54 0.5374 1.0 1985304 ChemDiv2_003233 CC(NC(=O)c1cc(=O)[nH]c2ccc(Br)cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C22 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985305 ChemDiv2_003234 OC(=O)c1cc(n[nH]1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C23 mock treatment 0.258 0.012 0.64 0.6449 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 C24 mock treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D01 compound treatment 0.234 -0.012 -0.64 -0.6449 -1.0 1985306 ChemDiv2_003235 OC(=O)CCS(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D02 compound treatment 0.293 0.047 2.53 2.5257 1.0 1345799 ChemDiv2_003236 Cc1ccc2occ(C(=O)c3ccccc3Cl)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D03 compound treatment 0.238 -0.008 -0.43 -0.4299 -1.0 1985307 ChemDiv2_003237 CN(CCN)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D04 compound treatment 0.29 0.044 2.36 2.3645 1.0 1985308 ChemDiv2_003238 Cc1c(C#N)c(N)nc(SCC(=O)c2ccc(Cl)cc2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D05 compound treatment 0.227 -0.019 -1.02 -1.021 -1.0 1985309 ChemDiv2_003239 OC(=O)C1(CCCCC1)NCc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D06 compound treatment 0.243 -0.003 -0.16 -0.1612 -1.0 1659920 ChemDiv2_003240 CN(C)CCSc1nc2ccccc2n1CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D07 compound treatment 0.233 -0.013 -0.7 -0.6986 -1.0 1985310 ChemDiv2_003241 OCC1Cc2ccccc2CN1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D08 compound treatment 0.247 0.001 0.05 0.0537 1.0 1536419 ChemDiv2_003242 Oc1nc2SCCCn2c(=O)c1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D09 compound treatment 0.231 -0.015 -0.81 -0.8061 -1.0 1985311 ChemDiv2_003243 Cc1ccc2OC3(CCCC3)CC(SCC(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D10 compound treatment 0.395 0.149 8.01 8.0069 1.0 1016637 ChemDiv2_003244 C(Cc1ccccc1)Sc2ncnc3[nH]cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D11 compound treatment 0.314 0.068 3.65 3.6542 1.0 1985312 ChemDiv2_003245 COc1ccc(Nc2ncc(C(=O)O)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D12 compound treatment 0.266 0.02 1.07 1.0748 1.0 1430303 ChemDiv2_003246 CCOc1ccccc1C2CC(=O)Nc3c2ccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D13 compound treatment 0.247 0.001 0.05 0.0537 1.0 1985313 ChemDiv2_003247 COC(=O)c1ccccc1n2cnnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D14 compound treatment 0.254 0.008 0.43 0.4299 1.0 1291835 ChemDiv2_003248 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D15 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1282181 ChemDiv2_003249 CN(C)c1cc(nc(N)n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D16 compound treatment 0.593 0.347 18.65 18.6471 1.0 1379521 ChemDiv2_003250 CC(=O)Nc1ccc2n(cnc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D17 compound treatment 0.411 0.165 8.87 8.8668 1.0 1249059 ChemDiv2_003251 Oc1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N3CCCCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D18 compound treatment 0.4 0.154 8.28 8.2756 1.0 1399394 ChemDiv2_003252 COc1cc(NC(=O)CCc2ccccc2)nc(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D19 compound treatment 0.262 0.016 0.86 0.8598 1.0 1044908 ChemDiv2_003253 CCOC(=O)c1cnn(c1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D20 compound treatment 0.247 0.001 0.05 0.0537 1.0 1503681 ChemDiv2_003254 OC(CN1CCCC1)Cn2c3ccccc3c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D21 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1985314 ChemDiv2_003255 Cc1ccc(OC(=O)c2cccc(n2)C(=O)Oc3ccc(C)cn3)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D22 compound treatment 0.274 0.028 1.5 1.5047 1.0 1539048 ChemDiv2_003256 CCCn1c(SCCO)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D23 mock treatment 0.237 -0.009 -0.48 -0.4836 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 D24 mock treatment 0.24 -0.006 -0.32 -0.3224 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E01 compound treatment 0.227 -0.019 -1.02 -1.021 -1.0 1985315 ChemDiv2_003257 CCOC(=O)C1Sc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E02 compound treatment 0.468 0.222 11.93 11.9298 1.0 1985316 ChemDiv2_003258 O=C(NC1CCCC1)c2coc3nc4ccccc4nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E03 compound treatment 0.27 0.024 1.29 1.2897 1.0 1985317 ChemDiv2_003259 CCn1cc(C2=NCCO2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E04 compound treatment 0.387 0.141 7.58 7.577 1.0 1985318 ChemDiv2_003260 CCc1cccc(NC(=O)CSCCc2ccccn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E05 compound treatment 0.269 0.023 1.24 1.236 1.0 1985319 ChemDiv2_003261 Fc1ccc(CNC(=O)c2cc3CN(Cc3s2)C4CCCCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E06 compound treatment 0.254 0.008 0.43 0.4299 1.0 1723630 ChemDiv2_003262 COc1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E07 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1985320 ChemDiv2_003263 COC(=O)C1(N)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E08 compound treatment 0.349 0.103 5.54 5.535 1.0 1985321 ChemDiv2_003264 Clc1ccc(NC(=O)CNC(=O)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E09 compound treatment 0.279 0.033 1.77 1.7734 1.0 1985322 ChemDiv2_003265 Cc1ccccc1CSCCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E10 compound treatment 0.261 0.015 0.81 0.8061 1.0 1985323 ChemDiv2_003266 O=C(Cc1ccc(cc1)n2cccc2)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E11 compound treatment 0.252 0.006 0.32 0.3224 1.0 1985324 ChemDiv2_003267 COC(=O)c1cnn2c(O)cc(CCl)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E12 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1985325 ChemDiv2_003268 OC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E13 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985326 ChemDiv2_003269 CC1CCCC(NC(=O)c2ccccc2C(=O)O)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E14 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985327 ChemDiv2_003270 COC(=O)c1cc(cn1C)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E15 compound treatment 0.252 0.006 0.32 0.3224 1.0 1985328 ChemDiv2_003271 O=C(CNC(=O)c1cccs1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E16 compound treatment 0.259 0.013 0.7 0.6986 1.0 1021691 ChemDiv2_003272 Cc1nc(C)c(cc1C(=O)O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E17 compound treatment 0.257 0.011 0.59 0.5911 1.0 1985329 ChemDiv2_003273 CCS(=O)(=O)N1CCC(CC1)C(=O)N2CCC3(CC2)OCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E18 compound treatment 0.29 0.044 2.36 2.3645 1.0 1985330 ChemDiv2_003274 COc1ccc(C/C(=N/O)/N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E19 compound treatment 0.272 0.026 1.4 1.3972 1.0 1985331 ChemDiv2_003275 Cc1ccc(CS(=O)(=O)CCC(=O)NCc2ccc3OCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E20 compound treatment 0.256 0.01 0.54 0.5374 1.0 1223785 ChemDiv2_003276 OC(=O)C1COc2ccccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E21 compound treatment 0.258 0.012 0.64 0.6449 1.0 1985332 ChemDiv2_003277 CC1CCCC(NC(=O)c2cc(=O)[nH]c3ccc(Br)cc23)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E22 compound treatment 0.465 0.219 11.77 11.7686 1.0 1985333 ChemDiv2_003278 CCOC(=O)COc1nc(C)cc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E23 mock treatment 0.248 0.002 0.11 0.1075 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 E24 mock treatment 0.243 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F01 compound treatment 0.232 -0.014 -0.75 -0.7523 -1.0 1037610 ChemDiv2_003279 OC(=O)c1ccc(cc1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F02 compound treatment 0.247 0.001 0.05 0.0537 1.0 1985334 ChemDiv2_003280 CCC(=O)Nc1c(C)n[nH]c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F03 compound treatment 0.253 0.007 0.38 0.3762 1.0 1985335 ChemDiv2_003281 CCN(CCCN)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F04 compound treatment 0.452 0.206 11.07 11.07 1.0 1277069 ChemDiv2_003282 CC1C(=C(NC2=C1C(=O)CC(C)(C)C2)SCC(=O)c3ccc(Cl)cc3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F05 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1985336 ChemDiv2_003283 NC1C(Cc2ccco2)CCc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F06 compound treatment 0.389 0.143 7.68 7.6845 1.0 1468020 ChemDiv2_003284 Fc1ccccc1C(=O)NCCN2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F07 compound treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1574844 ChemDiv2_003285 CC(N1CC(CC1=O)C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F08 compound treatment 0.424 0.178 9.57 9.5653 1.0 1012498 ChemDiv2_003286 OC(=O)CCSc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F09 compound treatment 0.395 0.149 8.01 8.0069 1.0 1136803 ChemDiv2_003287 OC(=O)c1ccc2n(cnc2c1)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F10 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1032899 ChemDiv2_003288 CC(=O)Nc1ncnc2[nH]cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F11 compound treatment 0.227 -0.019 -1.02 -1.021 -1.0 1985337 ChemDiv2_003289 OC(=O)c1cc(on1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F12 compound treatment 0.36 0.114 6.13 6.1261 1.0 1577297 ChemDiv2_003290 Cc1ccc(OCCn2c(SCC(=O)N)nc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F13 compound treatment 0.235 -0.011 -0.59 -0.5911 -1.0 1985338 ChemDiv2_003291 CCCOC1=NOC2C3CCC(C3)C21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F14 compound treatment 0.383 0.137 7.36 7.3621 1.0 1921452 ChemDiv2_003292 CN1CCN(CCCNC(=O)c2sc3ccccc3c2Cl)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F15 compound treatment 0.24 -0.006 -0.32 -0.3224 -1.0 1985339 ChemDiv2_003293 Nc1nnc(CCC(=O)O)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F16 compound treatment 0.306 0.06 3.22 3.2243 1.0 1200972 ChemDiv2_003294 CC(=O)Nc1ccc2n(Cc3ccccc3)c(C)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F17 compound treatment 0.261 0.015 0.81 0.8061 1.0 1096123 ChemDiv2_003295 CCN(CC)c1ccc2cc(c3nc4ccccc4n3C)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F18 compound treatment 0.262 0.016 0.86 0.8598 1.0 1508019 ChemDiv2_003296 Cc1cc(C)cc(OC(=O)CN2C(=O)c3ccccc3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F19 compound treatment 0.262 0.016 0.86 0.8598 1.0 1415000 ChemDiv2_003297 Cc1cc(NC(=O)c2ccco2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F20 compound treatment 0.286 0.04 2.15 2.1495 1.0 1230287 ChemDiv2_003298 O=C(NC1CCCCC1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F21 compound treatment 0.253 0.007 0.38 0.3762 1.0 1656911 ChemDiv2_003299 Cn1c(=O)c(nc2ccccc12)c3ccccc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F22 compound treatment 0.444 0.198 10.64 10.6401 1.0 1276735 ChemDiv2_003300 COc1ccc(Cc2nnc(N)s2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F23 mock treatment 0.25 0.004 0.21 0.215 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 F24 mock treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G01 compound treatment 0.229 -0.017 -0.91 -0.9135 -1.0 1524354 ChemDiv2_003301 OC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G02 compound treatment 0.298 0.052 2.79 2.7944 1.0 1985340 ChemDiv2_003302 CCC(C(=O)Nc1ccccc1CC)n2nc(ccc2=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G03 compound treatment 0.241 -0.005 -0.27 -0.2687 -1.0 1985341 ChemDiv2_003303 OC(=O)C1CSC(=N1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G04 compound treatment 0.301 0.055 2.96 2.9556 1.0 1985342 ChemDiv2_003304 COC(=O)c1cc2OCOc2cc1NC(=O)CSCCc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G05 compound treatment 0.459 0.213 11.45 11.4462 1.0 1985343 ChemDiv2_003305 COc1ccc(Cl)cc1NC(=O)C2CSC(=N2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G06 compound treatment 0.232 -0.014 -0.75 -0.7523 -1.0 1661784 ChemDiv2_003306 CCCC(=O)Nc1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G07 compound treatment 0.322 0.076 4.08 4.0841 1.0 1985344 ChemDiv2_003307 CCC1CN(C(=O)CCC(=O)NCc2ccc(F)cc2)c3cc(Cl)ccc3O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G08 compound treatment 0.259 0.013 0.7 0.6986 1.0 1985345 ChemDiv2_003308 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G09 compound treatment 0.289 0.043 2.31 2.3107 1.0 1268668 ChemDiv2_003309 Clc1ccccc1CSCC(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G10 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985346 ChemDiv2_003310 O=C(Cc1ccc(cc1)n2cccc2)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G11 compound treatment 0.335 0.089 4.78 4.7827 1.0 1985347 ChemDiv2_003311 O=C(N1CCC2(CC1)OCCO2)c3ccc4SCC(=O)N(Cc5ccccc5)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G12 compound treatment 0.258 0.012 0.64 0.6449 1.0 1985348 ChemDiv2_003312 C(C1CNc2ccccc2CN1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G13 compound treatment 0.276 0.03 1.61 1.6121 1.0 1985349 ChemDiv2_003313 Cc1ccc2OC(CNc2c1)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G14 compound treatment 0.383 0.137 7.36 7.3621 1.0 1985350 ChemDiv2_003314 COC(=O)CS(=O)(=O)c1ccc2NC(=O)Cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G15 compound treatment 0.263 0.017 0.91 0.9135 1.0 1985351 ChemDiv2_003315 Brc1ccccc1CC(=O)N(CCCN2CCOCC2)Cc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G16 compound treatment 0.248 0.002 0.11 0.1075 1.0 1782008 ChemDiv2_003316 Nc1cc(=O)[nH]c(=O)n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G17 compound treatment 0.247 0.001 0.05 0.0537 1.0 1985352 ChemDiv2_003317 CCS(=O)(=O)N1CCC(CC1)C(=O)NCCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G18 compound treatment 0.251 0.005 0.27 0.2687 1.0 1985353 ChemDiv2_003318 CN(C)c1ccc(cc1)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G19 compound treatment 0.335 0.089 4.78 4.7827 1.0 1985354 ChemDiv2_003319 Clc1ccccc1CSCC(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G20 compound treatment 0.265 0.019 1.02 1.021 1.0 1272853 ChemDiv2_003320 OC(=O)c1n[nH]c2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G21 compound treatment 0.253 0.007 0.38 0.3762 1.0 1985355 ChemDiv2_003321 Brc1ccc2[nH]c(=O)cc(C(=O)NC3CC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G22 compound treatment 0.262 0.016 0.86 0.8598 1.0 1985356 ChemDiv2_003322 CCOC(=O)CCc1c(C)n[nH]c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G23 mock treatment 0.252 0.006 0.32 0.3224 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 G24 mock treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H01 compound treatment 0.242 -0.004 -0.21 -0.215 -1.0 1985357 ChemDiv2_003323 CC1CNCCN1c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H02 compound treatment 0.417 0.171 9.19 9.1892 1.0 1917636 ChemDiv2_003324 C(CSc1nc2ccccc2s1)CN3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H03 compound treatment 0.25 0.004 0.21 0.215 1.0 1985358 ChemDiv2_003325 CCN1CCN(CCCN)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H04 compound treatment 0.368 0.122 6.56 6.556 1.0 1985359 ChemDiv2_003326 Nc1ccc(cc1)c2nc(nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H05 compound treatment 0.249 0.003 0.16 0.1612 1.0 1603122 ChemDiv2_003327 OC(=O)C1CN(C(=O)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H06 compound treatment 0.251 0.005 0.27 0.2687 1.0 1019716 ChemDiv2_003328 CN1CCN(CCN2C(=O)c3ccccc3C2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H07 compound treatment 0.242 -0.004 -0.21 -0.215 -1.0 1985360 ChemDiv2_003329 Cc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H08 compound treatment 0.326 0.08 4.3 4.299 1.0 1359239 ChemDiv2_003330 Clc1ccc(cc1)S(=O)(=O)NCC(N2CCNCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H09 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985361 ChemDiv2_003331 OC(=O)COc1ccc2nccnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H10 compound treatment 0.252 0.006 0.32 0.3224 1.0 1653418 ChemDiv2_003332 Cn1cnc2n(C)c(=O)n(Cc3ccccc3)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H11 compound treatment 0.275 0.029 1.56 1.5584 1.0 1985362 ChemDiv2_003333 OC(=O)c1cc(on1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H12 compound treatment 0.266 0.02 1.07 1.0748 1.0 1780856 ChemDiv2_003334 CCCOC(=O)CNc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H13 compound treatment 0.247 0.001 0.05 0.0537 1.0 1253944 ChemDiv2_003335 CC(C)OC(=O)C1CC(C)(O)C(=O)C(C1c2ccc(F)cc2)C(=O)OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H14 compound treatment 0.489 0.243 13.06 13.0583 1.0 1190508 ChemDiv2_003336 CCOC(=O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3oc2=N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H15 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1210633 ChemDiv2_003337 COc1ccc(CCN2C(=O)c3ccccc3C2(O)c4ncc[nH]4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H16 compound treatment 0.463 0.217 11.66 11.6611 1.0 1985363 ChemDiv2_003338 CC(=O)Nc1ccc2n(cnc2c1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H17 compound treatment 0.262 0.016 0.86 0.8598 1.0 1400078 ChemDiv2_003339 O=c1cccc([nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H18 compound treatment 0.441 0.195 10.48 10.4789 1.0 1412523 ChemDiv2_003340 CC(C)c1ccc(OC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H19 compound treatment 0.243 -0.003 -0.16 -0.1612 -1.0 1985364 ChemDiv2_003341 CCCCc1nc(no1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H20 compound treatment 0.264 0.018 0.97 0.9673 1.0 1409356 ChemDiv2_003342 O=C(Nc1nccs1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H21 compound treatment 0.236 -0.01 -0.54 -0.5374 -1.0 1380103 ChemDiv2_003343 COc1ccc(cc1)C(=O)n2c(=O)oc3ccc(Cl)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H22 compound treatment 0.4 0.154 8.28 8.2756 1.0 1918900 ChemDiv2_003344 O=c1[nH]nc(SCc2ccccc2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H23 mock treatment 0.248 0.002 0.11 0.1075 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 H24 mock treatment 0.234 -0.012 -0.64 -0.6449 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I01 compound treatment 0.213 -0.033 -1.77 -1.7734 -1.0 1985365 ChemDiv2_003345 COC(=O)CN1C(=O)C(OC(=O)C)S(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I02 compound treatment 0.371 0.125 6.72 6.7172 1.0 1985366 ChemDiv2_003346 CCC(C(=O)Nc1cccc(Cl)c1)n2nc(ccc2=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I03 compound treatment 0.35 0.104 5.59 5.5887 1.0 1985367 ChemDiv2_003347 Cc1ccc(CNC(=O)C2CSC(=N2)c3cccs3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I04 compound treatment 0.469 0.223 11.98 11.9836 1.0 1985368 ChemDiv2_003348 CCOc1ccc(OCC)c(NC(=O)CSCCc2ccccn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I05 compound treatment 0.496 0.25 13.43 13.4345 1.0 1985369 ChemDiv2_003349 Fc1cc(Br)ccc1NC(=O)C2CSC(=N2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I06 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1985370 ChemDiv2_003350 OC(=O)CCS(=O)(=O)c1ccc2[nH]c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I07 compound treatment 0.243 -0.003 -0.16 -0.1612 -1.0 1985371 ChemDiv2_003351 Cc1c2C(N(Cc3ccccc3)C(=O)c2c(C)n1C)C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I08 compound treatment 0.414 0.168 9.03 9.028 1.0 1985372 ChemDiv2_003352 CCOc1ccc2nc(sc2c1)C(=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I09 compound treatment 0.398 0.152 8.17 8.1682 1.0 1985373 ChemDiv2_003353 Clc1ccccc1CSCCC(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I10 compound treatment 0.259 0.013 0.7 0.6986 1.0 1985374 ChemDiv2_003354 CCc1ccccc1NC(=O)Cc2ccc(cc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I11 compound treatment 0.266 0.02 1.07 1.0748 1.0 1985375 ChemDiv2_003355 CCN1C(=O)CSc2ccc(cc12)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I12 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985376 ChemDiv2_003356 OC(=O)C(Cc1ccccc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I13 compound treatment 0.419 0.173 9.3 9.2967 1.0 1985377 ChemDiv2_003357 Cc1ccc2OC(CNc2c1)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I14 compound treatment 0.256 0.01 0.54 0.5374 1.0 1419847 ChemDiv2_003358 Cc1ccccc1CN2CCN(CC2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I15 compound treatment 0.254 0.008 0.43 0.4299 1.0 1985378 ChemDiv2_003359 CS(=O)(=O)N1CCC(CC1)C(=O)NC2CCCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I16 compound treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1985379 ChemDiv2_003360 C(Nc1ccncc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I17 compound treatment 0.372 0.126 6.77 6.771 1.0 1985380 ChemDiv2_003361 COc1cccc(CNC(=O)CCSCc2ccccc2F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I18 compound treatment 0.255 0.009 0.48 0.4836 1.0 1985381 ChemDiv2_003362 N/C(=N\O)/c1cccc(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I19 compound treatment 0.257 0.011 0.59 0.5911 1.0 1985382 ChemDiv2_003363 Cc1ccc(CS(=O)(=O)CCC(=O)NCC2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I20 compound treatment 0.253 0.007 0.38 0.3762 1.0 1316765 ChemDiv2_003364 CC(C)c1cc([nH]n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I21 compound treatment 0.256 0.01 0.54 0.5374 1.0 1985383 ChemDiv2_003365 COc1ccc(CCNC(=O)c2cc(=O)[nH]c3ccc(Br)cc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I22 compound treatment 0.277 0.031 1.67 1.6659 1.0 1985384 ChemDiv2_003366 OC(=O)c1n[nH]c-2c1COc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I23 mock treatment 0.252 0.006 0.32 0.3224 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 I24 mock treatment 0.252 0.006 0.32 0.3224 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J01 compound treatment 0.248 0.002 0.11 0.1075 1.0 1043915 ChemDiv2_003367 NC1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J02 compound treatment 0.267 0.021 1.13 1.1285 1.0 1985385 ChemDiv2_003368 CCc1cc2c(NCCCC(=O)O)ncnc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J03 compound treatment 0.247 0.001 0.05 0.0537 1.0 1204374 ChemDiv2_003369 CCN1CCN(CCN)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J04 compound treatment 0.261 0.015 0.81 0.8061 1.0 1933791 ChemDiv2_003370 COc1cc(nc(N)n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J05 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1985386 ChemDiv2_003371 CC(C)(NCc1ccccc1Cl)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J06 compound treatment 0.336 0.09 4.84 4.8364 1.0 1985387 ChemDiv2_003372 C(c1noc(n1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J07 compound treatment 0.242 -0.004 -0.21 -0.215 -1.0 1985388 ChemDiv2_003373 NC(CO)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J08 compound treatment 0.41 0.164 8.81 8.813 1.0 1620849 ChemDiv2_003374 Nc1ccc(cc1)C(=O)OCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J09 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1676366 ChemDiv2_003375 Cc1nn(Cc2ccccc2)c(C)c1CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J10 compound treatment 0.248 0.002 0.11 0.1075 1.0 1735582 ChemDiv2_003376 Fc1cc(F)nc(NCc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J11 compound treatment 0.24 -0.006 -0.32 -0.3224 -1.0 1985389 ChemDiv2_003377 OC(=O)c1cc2ncc(Br)cn2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J12 compound treatment 0.242 -0.004 -0.21 -0.215 -1.0 1779134 ChemDiv2_003378 COC(=O)C(C)Nc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J13 compound treatment 0.253 0.007 0.38 0.3762 1.0 1388025 ChemDiv2_003379 Nc1nonc1NC(=O)COC2CN3CCC2CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J14 compound treatment 0.265 0.019 1.02 1.021 1.0 1309236 ChemDiv2_003380 Cc1ccc(NC(=O)c2c(O)c3ccccc3[nH]c2=O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J15 compound treatment 0.24 -0.006 -0.32 -0.3224 -1.0 1985390 ChemDiv2_003381 C(CNc1c2CCCc2nc3ccccc13)CN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J16 compound treatment 0.269 0.023 1.24 1.236 1.0 1985391 ChemDiv2_003382 Cn1c(nc2ccccc12)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J17 compound treatment 0.27 0.024 1.29 1.2897 1.0 1577648 ChemDiv2_003383 CC(C)Cc1cc(c(C#N)c(N)n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J18 compound treatment 0.253 0.007 0.38 0.3762 1.0 1330843 ChemDiv2_003384 Clc1ccc(NC(=O)c2cc3ccccc3oc2=N)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J19 compound treatment 0.537 0.291 15.64 15.6377 1.0 1985392 ChemDiv2_003385 Nc1ccc(Sc2nc3ccccc3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J20 compound treatment 0.272 0.026 1.4 1.3972 1.0 1137064 ChemDiv2_003386 COC(=O)c1ccccc1NC(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J21 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1985393 ChemDiv2_003387 CCC(=O)n1c(=O)oc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J22 compound treatment 0.248 0.002 0.11 0.1075 1.0 1510499 ChemDiv2_003388 Fc1ccccc1C(=O)Oc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J23 mock treatment 0.237 -0.009 -0.48 -0.4836 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 J24 mock treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K01 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1985394 ChemDiv2_003389 OC(=O)C1CSC(=N1)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K02 compound treatment 0.324 0.078 4.19 4.1916 1.0 1985395 ChemDiv2_003390 CCC(C(=O)NCc1ccco1)n2nc(ccc2=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K03 compound treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1985396 ChemDiv2_003391 OC(=O)C1CNC(=N1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K04 compound treatment 0.272 0.026 1.4 1.3972 1.0 1985397 ChemDiv2_003392 COc1ccc(OC)c(c1)C2CC(=O)C(C(C)C)C(N2)c3cc(OC)ccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K05 compound treatment 0.452 0.206 11.07 11.07 1.0 1985398 ChemDiv2_003393 CCOc1ccc(NC(=O)C2CSC(=N2)c3ccncc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K06 compound treatment 0.258 0.012 0.64 0.6449 1.0 1985399 ChemDiv2_003394 COC(=O)CCS(=O)(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K07 compound treatment 0.421 0.175 9.4 9.4041 1.0 1985400 ChemDiv2_003395 COC(=O)c1c(C)c(C)sc1NC(=O)C2CSC(=N2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K08 compound treatment 0.312 0.066 3.55 3.5467 1.0 1985401 ChemDiv2_003396 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K09 compound treatment 0.253 0.007 0.38 0.3762 1.0 1201383 ChemDiv2_003397 OC(=O)C1CC(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K10 compound treatment 0.233 -0.013 -0.7 -0.6986 -1.0 1985402 ChemDiv2_003398 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K11 compound treatment 0.269 0.023 1.24 1.236 1.0 1985403 ChemDiv2_003399 CC1CCN(CC1)C(=O)c2ccc3SCC(=O)N(CC=C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K12 compound treatment 0.316 0.07 3.76 3.7617 1.0 1985404 ChemDiv2_003400 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3c(C)noc3/C=C/NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K13 compound treatment 0.35 0.104 5.59 5.5887 1.0 1985405 ChemDiv2_003401 O=C(NCCC1=CCCCC1)C2CCN(CC2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K14 compound treatment 0.32 0.074 3.98 3.9766 1.0 1985406 ChemDiv2_003402 CC(C)OC(=O)CN1CCN(CC1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K15 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1985407 ChemDiv2_003403 CCC(C)NC(=O)C1CCN(CC1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K16 compound treatment 0.248 0.002 0.11 0.1075 1.0 1509994 ChemDiv2_003404 C(C#Cc1ccccc1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K17 compound treatment 0.358 0.112 6.02 6.0186 1.0 1985408 ChemDiv2_003405 CCOc1ccc(CNC(=O)CCSCc2ccccc2Cl)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K18 compound treatment 0.565 0.319 17.14 17.1424 1.0 1661453 ChemDiv2_003406 Nc1ccc(Oc2ccc3C(=O)N(Cc4cccnc4)C(=O)c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K19 compound treatment 0.258 0.012 0.64 0.6449 1.0 1985409 ChemDiv2_003407 Cc1ccc(CS(=O)(=O)CCC(=O)N2CCC3(CC2)OCCO3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K20 compound treatment 0.263 0.017 0.91 0.9135 1.0 1327346 ChemDiv2_003408 CS(=O)(=O)N1Cc2ccccc2CC1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K21 compound treatment 0.276 0.03 1.61 1.6121 1.0 1985410 ChemDiv2_003409 CC(C1Sc2ccccc2NC1=O)C(=O)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K22 compound treatment 0.248 0.002 0.11 0.1075 1.0 1920197 ChemDiv2_003410 Cc1cc(C)n(CC(=O)O)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K23 mock treatment 0.253 0.007 0.38 0.3762 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 K24 mock treatment 0.248 0.002 0.11 0.1075 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L01 compound treatment 0.228 -0.018 -0.97 -0.9673 -1.0 1005357 ChemDiv2_003411 O=C(c1cccs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L02 compound treatment 0.268 0.022 1.18 1.1822 1.0 1985411 ChemDiv2_003412 CCSc1nc(N)c(C#N)c(CC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L03 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985412 ChemDiv2_003413 NCCCN1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L04 compound treatment 0.247 0.001 0.05 0.0537 1.0 1670712 ChemDiv2_003414 Cc1cc(Oc2ccccc2)nc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L05 compound treatment 0.252 0.006 0.32 0.3224 1.0 1985413 ChemDiv2_003415 COc1ccc(cc1)C(N)CCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L06 compound treatment 0.262 0.016 0.86 0.8598 1.0 1275366 ChemDiv2_003416 Fc1ccc(NC(=O)c2cc3cc(Cl)cc(Cl)c3oc2=N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L07 compound treatment 0.234 -0.012 -0.64 -0.6449 -1.0 1985414 ChemDiv2_003417 OC(=O)C1CCC(=O)N1Cc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L08 compound treatment 0.25 0.004 0.21 0.215 1.0 1985415 ChemDiv2_003418 COc1ccc(cc1)C2SCC(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L09 compound treatment 0.242 -0.004 -0.21 -0.215 -1.0 1985416 ChemDiv2_003419 CCn1nc(C)c(CCC(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L10 compound treatment 0.362 0.116 6.23 6.2336 1.0 1985417 ChemDiv2_003420 Brc1ccc2oc(=O)c(cc2c1)c3nnc(o3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L11 compound treatment 0.237 -0.009 -0.48 -0.4836 -1.0 1985418 ChemDiv2_003421 OC(=O)CCCCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L12 compound treatment 0.288 0.042 2.26 2.257 1.0 1985419 ChemDiv2_003422 CCCOC(=O)CSc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L13 compound treatment 0.251 0.005 0.27 0.2687 1.0 1399997 ChemDiv2_003423 CCC1(C)OC(=O)N(C2CC(C)(C)NC(C)(C)C2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L14 compound treatment 0.532 0.286 15.37 15.369 1.0 1128356 ChemDiv2_003424 CC(=O)Nc1ccc(cc1)S(=O)(=O)n2cnc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L15 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1607154 ChemDiv2_003425 Cc1nnc(SCc2cc(=O)oc3cc(O)ccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L16 compound treatment 0.298 0.052 2.79 2.7944 1.0 1191437 ChemDiv2_003426 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(CCO)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L17 compound treatment 0.231 -0.015 -0.81 -0.8061 -1.0 1007329 ChemDiv2_003427 OC(=O)CN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L18 compound treatment 0.323 0.077 4.14 4.1378 1.0 1276347 ChemDiv2_003428 CCOc1ccc(Nc2c3-c4ccccc4C(=O)c5cccc([nH]c2=O)c53)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L19 compound treatment 0.288 0.042 2.26 2.257 1.0 1632067 ChemDiv2_003429 COC(=O)c1cc(=O)c2ccc(OC)cc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L20 compound treatment 0.288 0.042 2.26 2.257 1.0 1662752 ChemDiv2_003430 O=C(CCOc1ccccc1)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L21 compound treatment 0.304 0.058 3.12 3.1168 1.0 1331271 ChemDiv2_003431 CCN(CC)C(=O)CSc1nc2cc(Cl)ccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L22 compound treatment 0.263 0.017 0.91 0.9135 1.0 1655392 ChemDiv2_003432 Fc1cccc(c1)C(=O)Oc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L23 mock treatment 0.243 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 L24 mock treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M01 compound treatment 0.235 -0.011 -0.59 -0.5911 -1.0 1985420 ChemDiv2_003433 OC(=O)C1CNC(=N1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M02 compound treatment 0.357 0.111 5.96 5.9649 1.0 1985421 ChemDiv2_003434 CCC(C(=O)Nc1cccc(OC)c1)n2nc(ccc2=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M03 compound treatment 0.236 -0.01 -0.54 -0.5374 -1.0 1985422 ChemDiv2_003435 CCC1COC(=N1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M04 compound treatment 0.383 0.137 7.36 7.3621 1.0 1481 ChemDiv2_003436 Oc1c(Cc2c(O)c3ccccc3oc2=O)c(=O)oc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M05 compound treatment 0.291 0.045 2.42 2.4182 1.0 1985423 ChemDiv2_003437 O=C(NC1CC1)C2CSC(=N2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M06 compound treatment 0.238 -0.008 -0.43 -0.4299 -1.0 1985424 ChemDiv2_003438 CN(CC(=O)O)S(=O)(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M07 compound treatment 0.575 0.329 17.68 17.6798 1.0 1985425 ChemDiv2_003439 COC(=O)c1ccc2Sc3ccccc3C(=Nc2c1)Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M08 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1060483 ChemDiv2_003440 Clc1ccc(cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M09 compound treatment 0.262 0.016 0.86 0.8598 1.0 1302751 ChemDiv2_003441 Cc1ccc(Cc2c(C)nc3c(cnn3c2C)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M10 compound treatment 0.242 -0.004 -0.21 -0.215 -1.0 1985426 ChemDiv2_003442 COC(=O)CN1CCN(C(=O)c2ccc(F)cc2)c3ccccc3C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M11 compound treatment 0.26 0.014 0.75 0.7523 1.0 1985427 ChemDiv2_003443 CC(C)N(C)C1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M12 compound treatment 0.254 0.008 0.43 0.4299 1.0 1985428 ChemDiv2_003444 Cn1cnc(c1)S(=O)(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M13 compound treatment 0.298 0.052 2.79 2.7944 1.0 1985429 ChemDiv2_003445 O=C(NC1CCCCCC1)C2CCCN(C2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M14 compound treatment 0.308 0.062 3.33 3.3318 1.0 1985430 ChemDiv2_003446 CC(C)OC(=O)CN1CCN(CC1)C2c3ccccc3-c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M15 compound treatment 0.307 0.061 3.28 3.278 1.0 1985431 ChemDiv2_003447 CCS(=O)(=O)N1CCC(CC1)C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M16 compound treatment 0.258 0.012 0.64 0.6449 1.0 1458819 ChemDiv2_003448 COC(=O)c1ccccc1SN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M17 compound treatment 0.344 0.098 5.27 5.2663 1.0 1985432 ChemDiv2_003449 Clc1ccccc1CSCCC(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M18 compound treatment 0.257 0.011 0.59 0.5911 1.0 1013879 ChemDiv2_003450 OC(=O)Cc1ccccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M19 compound treatment 0.369 0.123 6.61 6.6098 1.0 1985433 ChemDiv2_003451 CCCS(=O)(=O)N1CCC(CC1)C(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M20 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1985434 ChemDiv2_003452 NC1(CC(=O)O)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M21 compound treatment 0.323 0.077 4.14 4.1378 1.0 1985435 ChemDiv2_003453 CC(C1Sc2ccccc2NC1=O)C(=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M22 compound treatment 0.251 0.005 0.27 0.2687 1.0 1985436 ChemDiv2_003454 OC(=O)c1c[nH]nc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M23 mock treatment 0.252 0.006 0.32 0.3224 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 M24 mock treatment 0.25 0.004 0.21 0.215 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N01 compound treatment 0.225 -0.021 -1.13 -1.1285 -1.0 1033916 ChemDiv2_003455 CC(C)(C)C1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N02 compound treatment 0.503 0.257 13.81 13.8106 1.0 1374247 ChemDiv2_003456 CCCc1ccc(cc1)C(=O)Nc2cnc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N03 compound treatment 0.247 0.001 0.05 0.0537 1.0 1985437 ChemDiv2_003457 CCOC(=O)Cc1nn2c(=O)cc(C)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N04 compound treatment 0.237 -0.009 -0.48 -0.4836 -1.0 1256595 ChemDiv2_003458 O=C(N1CCOCC1)c2ccccc2N3C(=O)c4cccc5cccc(C3=O)c45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N05 compound treatment 0.248 0.002 0.11 0.1075 1.0 1985438 ChemDiv2_003459 Cc1ccc(cc1C)C(N)CCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N06 compound treatment 0.243 -0.003 -0.16 -0.1612 -1.0 1922854 ChemDiv2_003460 O=c1[nH]c2CCCc2c(=O)n1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N07 compound treatment 0.241 -0.005 -0.27 -0.2687 -1.0 1985439 ChemDiv2_003461 Cc1ccc(CN2C(CCC2=O)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N08 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985440 ChemDiv2_003462 CSC1=C(C#N)C(C)CC(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N09 compound treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1554403 ChemDiv2_003463 CC1Cc2cc(ccc2O1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N10 compound treatment 0.293 0.047 2.53 2.5257 1.0 1287078 ChemDiv2_003464 C1CCC2(C1)Cc3ccccc3-c4nnc(c5ccco5)n42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N11 compound treatment 0.236 -0.01 -0.54 -0.5374 -1.0 1026143 ChemDiv2_003465 OCCN(Cc1ccccc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N12 compound treatment 0.257 0.011 0.59 0.5911 1.0 1140337 ChemDiv2_003466 CN(C1CCCCC1)C(=O)CN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N13 compound treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1985441 ChemDiv2_003467 Cc1ccc(o1)C2Nc3ccccc3C(C)(C)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N14 compound treatment 0.26 0.014 0.75 0.7523 1.0 1985442 ChemDiv2_003468 CCOC(=O)Cn1c2nc(C)nn2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N15 compound treatment 0.247 0.001 0.05 0.0537 1.0 1143839 ChemDiv2_003469 O=C1SC(Nc2ccccc2)C(=O)N1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N16 compound treatment 0.246 0.0 0.0 -1.0 -1.0 1985443 ChemDiv2_003470 CCOC(=O)N1CCN(CC1)C(=O)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N17 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1591259 ChemDiv2_003471 Oc1c(C(=O)Nc2ccc(Cl)c(Cl)c2)c(=O)[nH]c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N18 compound treatment 0.529 0.283 15.21 15.2078 1.0 1273037 ChemDiv2_003472 Nc1nnc(CCS(=O)(=O)c2ccc(Cl)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N19 compound treatment 0.379 0.133 7.15 7.1471 1.0 1382040 ChemDiv2_003473 CCC(Sc1nc2ccccc2o1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N20 compound treatment 0.328 0.082 4.41 4.4065 1.0 1233519 ChemDiv2_003474 O=C(CCOc1ccccc1)NCCc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N21 compound treatment 0.314 0.068 3.65 3.6542 1.0 1266598 ChemDiv2_003475 O=c1oc2ccccc2cc1c3csc(Nc4ccccc4)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N22 compound treatment 0.259 0.013 0.7 0.6986 1.0 1985444 ChemDiv2_003476 O=C(Cc1ccccc1)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N23 mock treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 N24 mock treatment 0.244 -0.002 -0.11 -0.1075 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O01 compound treatment 0.352 0.106 5.7 5.6962 1.0 1064546 ChemDiv2_003477 OC(=O)C1CSC(=N1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O02 compound treatment 0.288 0.042 2.26 2.257 1.0 1985445 ChemDiv2_003478 COc1ccc(cc1)c2ccc(=O)n(Cc3c(F)cccc3Cl)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O03 compound treatment 0.307 0.061 3.28 3.278 1.0 1985446 ChemDiv2_003479 CSCCC1COC(=N1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O04 compound treatment 0.282 0.036 1.93 1.9346 1.0 1985447 ChemDiv2_003480 CCc1ccc2cc(CNC3CCCCC3)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O05 compound treatment 0.395 0.149 8.01 8.0069 1.0 1985448 ChemDiv2_003481 O=C(NCc1ccccc1)c2cc(=O)nc3sc(nn23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O06 compound treatment 0.554 0.308 16.55 16.5513 1.0 1985449 ChemDiv2_003482 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)CC(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O07 compound treatment 0.341 0.095 5.11 5.1051 1.0 1985450 ChemDiv2_003483 Cc1ccc(CNC(=O)CCSCc2cccc(F)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O08 compound treatment 0.245 -0.001 -0.05 -0.0537 -1.0 1985451 ChemDiv2_003484 CC(C)(C)OC(=O)N1CCNc2ccccc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O09 compound treatment 0.585 0.339 18.22 18.2172 1.0 1985452 ChemDiv2_003485 OC(=O)c1ccc2Sc3ccccc3C(=Nc2c1)Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O10 compound treatment 0.267 0.021 1.13 1.1285 1.0 1985453 ChemDiv2_003486 CCOC(=O)c1cc(c2ccccc2)n(CC(=O)N3CCCC3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O11 compound treatment 0.514 0.268 14.4 14.4018 1.0 1985454 ChemDiv2_003487 O=C(CCC1CC(=O)Nc2ccccc12)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O12 compound treatment 0.253 0.007 0.38 0.3762 1.0 1985455 ChemDiv2_003488 Cc1ccc(CNS(=O)(=O)c2cn(C)cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O13 compound treatment 0.258 0.012 0.64 0.6449 1.0 1985456 ChemDiv2_003489 O=C(CNC(=O)c1cccs1)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O14 compound treatment 0.239 -0.007 -0.38 -0.3762 -1.0 1985457 ChemDiv2_003490 Cc1n[nH]c(C)c1CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O15 compound treatment 0.251 0.005 0.27 0.2687 1.0 1985458 ChemDiv2_003491 CCS(=O)(=O)N1CCC(CC1)C(=O)NC2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O16 compound treatment 0.264 0.018 0.97 0.9673 1.0 1467971 ChemDiv2_003492 O=C1N(CC2NCCc3ccccc23)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O17 compound treatment 0.431 0.185 9.94 9.9415 1.0 1985459 ChemDiv2_003493 Clc1cccc(CSCCC(=O)NC2CCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O18 compound treatment 0.252 0.006 0.32 0.3224 1.0 1985460 ChemDiv2_003494 COC(=O)C1Cc2nc[nH]c2C(N1)c3ccc(OC)c(OC)c3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O19 compound treatment 0.254 0.008 0.43 0.4299 1.0 1985461 ChemDiv2_003495 CCCS(=O)(=O)N1CCC(CC1)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O20 compound treatment 0.249 0.003 0.16 0.1612 1.0 1985462 ChemDiv2_003496 CCOC(=O)CC1(N)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O21 compound treatment 0.457 0.211 11.34 11.3387 1.0 1985463 ChemDiv2_003497 O=C(NCC1CCCO1)c2coc3nc4ccccc4nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O22 compound treatment 0.269 0.023 1.24 1.236 1.0 1131065 ChemDiv2_003498 Nc1ccn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O23 mock treatment 0.255 0.009 0.48 0.4836 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 O24 mock treatment 0.247 0.001 0.05 0.0537 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P01 compound treatment 0.211 -0.035 -1.88 -1.8808 -1.0 1985464 ChemDiv2_003499 CC1CCN(CCCN)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P02 compound treatment 0.262 0.016 0.86 0.8598 1.0 1149770 ChemDiv2_003500 OC(=O)c1cccc2c(CN3CCN(CC3)C(c4ccccc4)c5ccccc5)c[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P03 compound treatment 0.203 -0.043 -2.31 -2.3107 -1.0 1645151 ChemDiv2_003501 OC(=O)C1CCC(CNCc2cccnc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P04 compound treatment 0.221 -0.025 -1.34 -1.3434 -1.0 1985465 ChemDiv2_003502 CN(C)CCSc1nc(C)cc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P05 compound treatment 0.21 -0.036 -1.93 -1.9346 -1.0 1985466 ChemDiv2_003503 OC(=O)C1CCC(=O)N1C2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P06 compound treatment 0.226 -0.02 -1.07 -1.0748 -1.0 1536614 ChemDiv2_003504 CCOc1ccccc1N2C(=O)CC(Nc3ccccc3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P07 compound treatment 0.227 -0.019 -1.02 -1.021 -1.0 1985467 ChemDiv2_003505 Cc1cccc(N2CCN(CCN)CC2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P08 compound treatment 0.48 0.234 12.57 12.5747 1.0 1985468 ChemDiv2_003506 CSc1nnc(o1)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P09 compound treatment 0.225 -0.021 -1.13 -1.1285 -1.0 1862472 ChemDiv2_003507 Nc1ccc(CN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P10 compound treatment 0.468 0.222 11.93 11.9298 1.0 1466134 ChemDiv2_003508 COc1ccccc1NC(=O)c2cc3cc(Br)ccc3oc2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P11 compound treatment 0.233 -0.013 -0.7 -0.6986 -1.0 1606924 ChemDiv2_003509 OCCNC(=O)Cc1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P12 compound treatment 0.266 0.02 1.07 1.0748 1.0 1985469 ChemDiv2_003510 CCOC(=O)c1sc(NC(=O)CN2C(=O)c3ccccc3C2=O)c(C(=O)OCC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P13 compound treatment 0.232 -0.014 -0.75 -0.7523 -1.0 1335094 ChemDiv2_003511 OC(=O)CCC(=O)N1CCN(CC1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P14 compound treatment 0.287 0.041 2.2 2.2033 1.0 1150115 ChemDiv2_003512 O=C(Nc1nc2ccccc2n1CCN3CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P15 compound treatment 0.222 -0.024 -1.29 -1.2897 -1.0 1047100 ChemDiv2_003513 Cc1cc(C(=O)N)c2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P16 compound treatment 0.241 -0.005 -0.27 -0.2687 -1.0 1628981 ChemDiv2_003514 O=C1CSC(N1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P17 compound treatment 0.231 -0.015 -0.81 -0.8061 -1.0 1014454 ChemDiv2_003515 O=c1oc(nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P18 compound treatment 0.298 0.052 2.79 2.7944 1.0 1572497 ChemDiv2_003516 CC(=O)Nc1nnc(CCS(=O)(=O)c2ccc3ccccc3c2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P19 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1985470 ChemDiv2_003517 CC(=O)NCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P20 compound treatment 0.234 -0.012 -0.64 -0.6449 -1.0 1985471 ChemDiv2_003518 Cc1cc(C)nc(SCCC(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P21 compound treatment 0.23 -0.016 -0.86 -0.8598 -1.0 1985472 ChemDiv2_003519 O=C(NC1=C(CCC1)C#N)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P22 compound treatment 0.254 0.008 0.43 0.4299 1.0 1930839 ChemDiv2_003520 Cc1nnc(SCc2ccccc2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P23 mock treatment 0.234 -0.012 -0.64 -0.6449 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1378 P24 mock treatment 0.236 -0.01 -0.54 -0.5374 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A01 compound treatment 0.225 -0.0242 -1.3 -1.3015 -1.0 1213399 ChemDiv2_003521 CCCc1cc2c(=O)c(coc2cc1OC)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A02 compound treatment 0.245 -0.00422 -0.23 -0.2267 -1.0 1609007 ChemDiv2_003522 Clc1ccc(OCc2nnc(NC(=O)C3CCCCC3)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A03 compound treatment 0.233 -0.0162 -0.87 -0.8716 -1.0 1294366 ChemDiv2_003523 COc1ccc(NC(=O)CSc2nc3cc4ccccc4cc3c(=O)n2CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A04 compound treatment 0.243 -0.00622 -0.33 -0.3342 -1.0 1271582 ChemDiv2_003524 O=C1N(CCCc2nc3ccccc3c(=O)n2Cc4ccco4)C(=O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A05 compound treatment 0.231 -0.0182 -0.98 -0.979 -1.0 1985473 ChemDiv2_003525 Cc1ccc(NC(=O)c2cnn(c2NC(=O)c3ccco3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A06 compound treatment 0.246 -0.00322 -0.17 -0.173 -1.0 1392176 ChemDiv2_003526 CCn1c(SCC(=O)OC)nc2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A07 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1620420 ChemDiv2_003527 C=CCn1c(Cc2ccccc2)nc3n(ncc3c1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A08 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1615833 ChemDiv2_003528 CCC(c1nnc(N)s1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A09 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1595774 ChemDiv2_003529 CCCSc1nc2n(C)c(=O)[nH]c(=O)c2n1C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A10 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1671963 ChemDiv2_003530 Nc1nnc(s1)c2ccccc2SCc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A11 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1705701 ChemDiv2_003531 COc1cc(OC)cc(c1)C(=O)N2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A12 compound treatment 0.235 -0.0142 -0.76 -0.7641 -1.0 1456152 ChemDiv2_003532 CC(=O)Nc1nc2ccccc2n1CCN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A13 compound treatment 0.525 0.276 14.82 14.8199 1.0 1420880 ChemDiv2_003533 CCn1c2ccccc2c3nnc(SCC(=O)Nc4ccc(cc4)S(=O)(=O)N)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A14 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1382489 ChemDiv2_003534 CCN(CC)CCn1c2nc(C)cn2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A15 compound treatment 0.462 0.213 11.43 11.4344 1.0 1985474 ChemDiv2_003535 CCC(=O)Nc1nc2CC(CC(=O)c2s1)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A16 compound treatment 0.242 -0.00722 -0.39 -0.3879 -1.0 1613265 ChemDiv2_003536 CC(C)Cn1c(=O)c2cc3c(=O)n(CC(C)C)c(=O)c3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A17 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1480506 ChemDiv2_003537 CCC(=O)OCCn1c(=O)c2cc3c(=O)n(CCOC(=O)CC)c(=O)c3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A18 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1123996 ChemDiv2_003538 CC(Oc1ccc2c(=O)c(Oc3ccccc3)c(C)oc2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A19 compound treatment 0.241 -0.00822 -0.44 -0.4417 -1.0 1445496 ChemDiv2_003539 C=CCn1c(=N)n(CC(=O)c2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A20 compound treatment 0.351 0.102 5.47 5.4695 1.0 1143616 ChemDiv2_003540 CN(C1CCS(=O)(=O)C1)C(=O)COc2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A21 compound treatment 0.241 -0.00822 -0.44 -0.4417 -1.0 1515649 ChemDiv2_003541 COc1ccc(OC(C)C(=O)Nc2nnc[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A22 compound treatment 0.285 0.0358 1.92 1.9228 1.0 1928306 ChemDiv2_003542 Oc1nc(SCC(=O)c2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A23 mock treatment 0.251 0.00178 0.1 0.0957 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 A24 mock treatment 0.26 0.0108 0.58 0.5794 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B01 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1321267 ChemDiv2_003543 COc1ccc(Cc2c(O)nc(SC)n(c3ccccc3)c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B02 compound treatment 0.319 0.0698 3.75 3.7499 1.0 1985475 ChemDiv2_003544 CCC(=O)Nc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B03 compound treatment 0.356 0.107 5.74 5.7382 1.0 1985476 ChemDiv2_003545 CCC(Sc1ccccn1)C(=O)Nc2ccc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B04 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1134754 ChemDiv2_003546 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B05 compound treatment 0.287 0.0378 2.03 2.0303 1.0 1274302 ChemDiv2_003547 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(cc3)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B06 compound treatment 0.283 0.0338 1.82 1.8153 1.0 1985477 ChemDiv2_003548 COC(=O)C1=CNC=C(C1c2cccc3ccccc23)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B07 compound treatment 0.27 0.0208 1.12 1.1167 1.0 1234602 ChemDiv2_003549 Cc1nc2ccc(Cc3ccc4nc(C)oc(=O)c4c3)cc2c(=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B08 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1714761 ChemDiv2_003550 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(C)cc3)C(=O)Nc4cc(C)ccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B09 compound treatment 0.332 0.0828 4.45 4.4485 1.0 1448706 ChemDiv2_003551 CCN(Cc1ccccc1)C(=O)CN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B10 compound treatment 0.252 0.00278 0.15 0.1495 1.0 1612493 ChemDiv2_003552 Cc1cccc(c1)C(=O)Nc2sc3CCCc3c2C(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B11 compound treatment 0.272 0.0228 1.22 1.2242 1.0 1285041 ChemDiv2_003553 COC(=O)CNC(=O)c1cc(nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B12 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1665381 ChemDiv2_003554 CCCC(=O)N1C(C2=C(CCCC2=O)Nc3ccccc13)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B13 compound treatment 0.32 0.0708 3.8 3.8036 1.0 1985478 ChemDiv2_003555 C=CCSc1nnc2n(c3ccccc3)c(=O)c4c5CCCc5sc4n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B14 compound treatment 0.264 0.0148 0.79 0.7943 1.0 1033505 ChemDiv2_003556 O=c1[nH]c2ccccc2c(=O)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B15 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1478188 ChemDiv2_003557 O=C(CN1C(=O)c2ccccc2C1=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B16 compound treatment 0.56 0.311 16.7 16.7007 1.0 1526658 ChemDiv2_003558 Cc1ccccc1c2nc3cc(NC(=O)c4cccs4)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B17 compound treatment 0.358 0.109 5.85 5.8457 1.0 1443126 ChemDiv2_003559 COc1ccccc1C(=O)Nc2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B18 compound treatment 0.252 0.00278 0.15 0.1495 1.0 1985479 ChemDiv2_003560 COc1ncnc2sc(C(=O)O)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B19 compound treatment 0.474 0.225 12.08 12.0793 1.0 1187503 ChemDiv2_003561 CCN(CC)Cc1c(O)c(CC)cc2c(=O)c(coc12)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B20 compound treatment 0.263 0.0138 0.74 0.7406 1.0 1985480 ChemDiv2_003562 CCN(C(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B21 compound treatment 0.275 0.0258 1.39 1.3854 1.0 1985481 ChemDiv2_003563 Clc1cccc(Oc2ncnc3c4ccccc4oc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B22 compound treatment 0.249 -2.19E-4 -0.01 -0.0118 -1.0 1411618 ChemDiv2_003564 Cc1ccc(cc1)c2nn(CC(=O)N)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B23 mock treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 B24 mock treatment 0.233 -0.0162 -0.87 -0.8716 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C01 compound treatment 0.291 0.0418 2.25 2.2452 1.0 1661025 ChemDiv2_003565 CCOC(=O)c1ccc(o1)c2coc3cc(O)c(CC)cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C02 compound treatment 0.25 7.81E-4 0.04 0.042 1.0 1146986 ChemDiv2_003566 OCCCN1C(=O)C2C3CC(C=C3)C2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C03 compound treatment 0.473 0.224 12.03 12.0255 1.0 1167604 ChemDiv2_003567 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ncn(Cc3ccccc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C04 compound treatment 0.362 0.113 6.06 6.0606 1.0 1564137 ChemDiv2_003568 CC(C)C(=O)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C05 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1322613 ChemDiv2_003569 Cc1c(CCN)c2cccc3CCCn1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C06 compound treatment 0.335 0.0858 4.61 4.6097 1.0 1729074 ChemDiv2_003570 Cn1c(=O)n(C)c2nc(SCc3ccc(F)cc3)n(Cc4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C07 compound treatment 0.27 0.0208 1.12 1.1167 1.0 1985482 ChemDiv2_003571 Cc1cc(C)nc(Nc2ccccc2Br)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C08 compound treatment 0.277 0.0278 1.49 1.4929 1.0 1186388 ChemDiv2_003572 COc1ccc(N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C09 compound treatment 0.27 0.0208 1.12 1.1167 1.0 1566137 ChemDiv2_003573 CCOC(=O)C(C)Sc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C10 compound treatment 0.309 0.0598 3.21 3.2125 1.0 1985483 ChemDiv2_003574 N#Cc1ccc(Sc2nc3ccccc3[nH]2)cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C11 compound treatment 0.316 0.0668 3.59 3.5887 1.0 1341100 ChemDiv2_003575 OC(COc1ccccc1C(=O)O)Cn2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C12 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1397415 ChemDiv2_003576 CCC(=O)Nc1nc2ccccc2n1CCN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C13 compound treatment 0.335 0.0858 4.61 4.6097 1.0 1625849 ChemDiv2_003577 O=C1N(CSc2nc3ccccc3[nH]2)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C14 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1286795 ChemDiv2_003578 CN(C)C(=O)c1cnn(c1NC(=O)c2ccc(Br)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C15 compound treatment 0.292 0.0428 2.3 2.299 1.0 1946553 ChemDiv2_003579 COc1nc(c2ccccc2)c3cc(C)ccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C16 compound treatment 0.25 7.81E-4 0.04 0.042 1.0 1706155 ChemDiv2_003580 CC(=O)Oc1ccc(cc1)N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C17 compound treatment 0.288 0.0388 2.08 2.084 1.0 1985484 ChemDiv2_003581 CC(C)(C)C(=O)OCCn1c(=O)c2cc3c(=O)n(CCOC(=O)C(C)(C)C)c(=O)c3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C18 compound treatment 0.263 0.0138 0.74 0.7406 1.0 1985485 ChemDiv2_003582 CCC(C)n1c(=O)[nH]c2CCCc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C19 compound treatment 0.272 0.0228 1.22 1.2242 1.0 1606911 ChemDiv2_003583 Cc1ccc(Cn2c(=N)n(CC(=O)c3ccco3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C20 compound treatment 0.264 0.0148 0.79 0.7943 1.0 1777351 ChemDiv2_003584 CCCCn1c(=O)[nH]c2CCCc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C21 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1526424 ChemDiv2_003585 CCCn1c(nc2c(=O)n(C)c(=O)[nH]c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C22 compound treatment 0.284 0.0348 1.87 1.8691 1.0 1033442 ChemDiv2_003586 Oc1nc(SCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C23 mock treatment 0.254 0.00478 0.26 0.2569 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 C24 mock treatment 0.249 -2.19E-4 -0.01 -0.0118 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D01 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1236687 ChemDiv2_003587 Fc1cccc(c1)C(=O)N2CCN(CC2)C(=O)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D02 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1724706 ChemDiv2_003588 Cc1ccc2nsnc2c1NC(=O)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D03 compound treatment 0.496 0.247 13.26 13.2615 1.0 1985486 ChemDiv2_003589 CCC(Sc1nc2ccccc2s1)C(=O)Nc3ccccc3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D04 compound treatment 0.285 0.0358 1.92 1.9228 1.0 1397326 ChemDiv2_003590 Cc1cccc(NC(=O)c2ccn(n2)C(=O)Oc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D05 compound treatment 0.269 0.0198 1.06 1.063 1.0 1089467 ChemDiv2_003591 Cc1cc(O)nc(n1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D06 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1149234 ChemDiv2_003592 OC(=O)C1C2OC3(CN(Cc4ccccc4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D07 compound treatment 0.281 0.0318 1.71 1.7079 1.0 1471918 ChemDiv2_003593 Clc1cc(nc(n1)N2CCCC2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D08 compound treatment 0.322 0.0728 3.91 3.9111 1.0 1666375 ChemDiv2_003594 CC(NC(=O)c1cc2cccc(CC=C)c2oc1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D09 compound treatment 0.444 0.195 10.47 10.4671 1.0 1588410 ChemDiv2_003595 OCCNc1cc(ncn1)n2nc(cc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D10 compound treatment 0.32 0.0708 3.8 3.8036 1.0 1697507 ChemDiv2_003596 O=c1n(c2ccccc2)c(nc3n(ncc13)c4ccccc4)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D11 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1650656 ChemDiv2_003597 Cc1nnc(SC2CC(=O)N(C2=O)c3ccc(C)cc3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D12 compound treatment 0.261 0.0118 0.63 0.6331 1.0 1985487 ChemDiv2_003598 CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D13 compound treatment 0.317 0.0678 3.64 3.6424 1.0 1444605 ChemDiv2_003599 CCSc1nc2sc3CN(C)CCc3c2c(=O)n1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D14 compound treatment 0.363 0.114 6.11 6.1144 1.0 1515816 ChemDiv2_003600 CCOc1cccc(c1)C(=O)Nc2cccc(c3nc4ccccc4[nH]3)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D15 compound treatment 0.265 0.0158 0.85 0.8481 1.0 1331335 ChemDiv2_003601 OC(Cn1c(=N)n(Cc2ccccc2)c3ccccc13)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D16 compound treatment 0.457 0.208 11.17 11.1657 1.0 1561694 ChemDiv2_003602 CCCC1CC(CSc2nc3ccccc3[nH]2)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D17 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1174383 ChemDiv2_003603 CCOc1ccc(cc1Br)C(=O)Nc2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D18 compound treatment 0.269 0.0198 1.06 1.063 1.0 1309572 ChemDiv2_003604 O=C(Cn1cnc2scc(c3ccccc3)c2c1=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D19 compound treatment 0.311 0.0618 3.32 3.32 1.0 1612854 ChemDiv2_003605 COC(=O)c1c(C)oc2ccc(O)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D20 compound treatment 0.286 0.0368 1.98 1.9765 1.0 1985488 ChemDiv2_003606 COc1ccccc1N2CCN(CC2)c3ncc(C(=O)Nc4cc(OC)c(OC)c(OC)c4)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D21 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1011785 ChemDiv2_003607 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D22 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1731728 ChemDiv2_003608 CCCOc1nnc(c2ccc(C)c(c2)S(=O)(=O)N(C)C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D23 mock treatment 0.242 -0.00722 -0.39 -0.3879 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 D24 mock treatment 0.239 -0.0102 -0.55 -0.5491 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E01 compound treatment 0.238 -0.0112 -0.6 -0.6029 -1.0 1569706 ChemDiv2_003609 CCCCn1c(=N)n(CC(O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E02 compound treatment 0.34 0.0908 4.88 4.8784 1.0 1948008 ChemDiv2_003610 Fc1ccc(NC(=O)CSc2nsc(SCC(=O)Nc3ccc(F)cc3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E03 compound treatment 0.373 0.124 6.65 6.6517 1.0 1926921 ChemDiv2_003611 Brc1ccc(cc1)c2nnc(SC(=O)OCc3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E04 compound treatment 0.261 0.0118 0.63 0.6331 1.0 1661495 ChemDiv2_003612 CC(C)CC(Nc1ncnc2ccc(C)cc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E05 compound treatment 0.265 0.0158 0.85 0.8481 1.0 1027121 ChemDiv2_003613 Cc1nc(c([nH]1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E06 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1068433 ChemDiv2_003614 CC1C(N(C)C(CC1=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E07 compound treatment 0.283 0.0338 1.82 1.8153 1.0 1710211 ChemDiv2_003615 Cc1cc(C)nc(Nc2ccccc2O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E08 compound treatment 0.246 -0.00322 -0.17 -0.173 -1.0 1293534 ChemDiv2_003616 OC(=O)CNc1ncnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E09 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1448443 ChemDiv2_003617 CN(C)c1nc2n(C)c(=O)[nH]c(=O)c2n1Cc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E10 compound treatment 0.253 0.00378 0.2 0.2032 1.0 1176262 ChemDiv2_003618 OC(CN1CCCCC1)Cn2c3CCCCc3c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E11 compound treatment 0.459 0.21 11.27 11.2732 1.0 1985489 ChemDiv2_003619 CCOc1ccc(OCCSc2nc3ccccc3n2CC(O)CO)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E12 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1225379 ChemDiv2_003620 CCC(=O)Nc1nc2ccccc2n1CCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E13 compound treatment 0.305 0.0558 3.0 2.9976 1.0 1985490 ChemDiv2_003621 Cc1nnc(SCC(=O)Nc2ccccn2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E14 compound treatment 0.285 0.0358 1.92 1.9228 1.0 1624516 ChemDiv2_003622 O=C(Nc1nccs1)C2CC2(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E15 compound treatment 0.535 0.286 15.36 15.3573 1.0 1673253 ChemDiv2_003623 COc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E16 compound treatment 0.547 0.298 16.0 16.0021 1.0 1985491 ChemDiv2_003624 Nc1cccc(c1)c2nnc(o2)c3cccc(N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E17 compound treatment 0.305 0.0558 3.0 2.9976 1.0 1286612 ChemDiv2_003625 O=C(Nc1c[nH]c(=O)[nH]c1=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(cc4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E18 compound treatment 0.495 0.246 13.21 13.2078 1.0 1623041 ChemDiv2_003626 O=C(CN1C(=O)c2ccccc2C1=O)OCc3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E19 compound treatment 0.426 0.177 9.5 9.4999 1.0 1701518 ChemDiv2_003627 COc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCN5CCN(CCO)CC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E20 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1690451 ChemDiv2_003628 O=c1[nH]c2CCCc2c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E21 compound treatment 0.325 0.0758 4.07 4.0723 1.0 1392568 ChemDiv2_003629 CCn1c2ccccc2c3nnc(SCC(=O)N4CCCc5ccccc45)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E22 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1483513 ChemDiv2_003630 CNc1nc2ccccc2n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E23 mock treatment 0.259 0.00978 0.53 0.5256 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 E24 mock treatment 0.251 0.00178 0.1 0.0957 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F01 compound treatment 0.29 0.0408 2.19 2.1915 1.0 1202698 ChemDiv2_003631 COc1ccc2ccccc2c1CN3CCN(CC3)C(=O)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F02 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1211430 ChemDiv2_003632 Cc1ccc2nsnc2c1NC(=O)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F03 compound treatment 0.516 0.267 14.34 14.3363 1.0 1196151 ChemDiv2_003633 Nc1nc(SCc2cnc(o2)c3ccccc3)nc4[nH]cnc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F04 compound treatment 0.413 0.164 8.8 8.8013 1.0 1575799 ChemDiv2_003634 COC(=O)n1ccc(n1)C(=O)Nc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F05 compound treatment 0.276 0.0268 1.44 1.4392 1.0 1985492 ChemDiv2_003635 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F06 compound treatment 0.441 0.192 10.31 10.3059 1.0 1565119 ChemDiv2_003636 CCC(Sc1nnc2c3ccccc3[nH]c2n1)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F07 compound treatment 0.454 0.205 11.0 11.0045 1.0 1518006 ChemDiv2_003637 COc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F08 compound treatment 0.467 0.218 11.7 11.7031 1.0 1196538 ChemDiv2_003638 O=C(Nc1ccc2oc(nc2c1)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F09 compound treatment 0.313 0.0638 3.43 3.4275 1.0 1616520 ChemDiv2_003639 COc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F10 compound treatment 0.525 0.276 14.82 14.8199 1.0 1409955 ChemDiv2_003640 O=C(Cc1ccccc1)Nc2cccc(c2)c3nc4ncccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F11 compound treatment 0.369 0.12 6.44 6.4368 1.0 1503587 ChemDiv2_003641 COc1cccc(c1)C(NC(=O)c2ccccc2)c3ccc4cccnc4c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F12 compound treatment 0.418 0.169 9.07 9.07 1.0 1985493 ChemDiv2_003642 CCOC(=O)CSc1nc(N)c2c3CCCCc3sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F13 compound treatment 0.274 0.0248 1.33 1.3317 1.0 1654439 ChemDiv2_003643 CCOC(=O)c1c(NC(=O)C)sc2c(OCC(O)CNC(C)(C)C)c(Br)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F14 compound treatment 0.426 0.177 9.5 9.4999 1.0 1863043 ChemDiv2_003644 COc1ccc(cc1NC(=O)C)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F15 compound treatment 0.447 0.198 10.63 10.6284 1.0 1295749 ChemDiv2_003645 Nc1nnc(SCC(=O)n2c3ccccc3c4ccccc24)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F16 compound treatment 0.392 0.143 7.67 7.6728 1.0 1443603 ChemDiv2_003646 CCCCC1CC(CSc2nnc[nH]2)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F17 compound treatment 0.288 0.0388 2.08 2.084 1.0 1985494 ChemDiv2_003647 CCCCC(=O)Nc1cccc2nsnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F18 compound treatment 0.403 0.154 8.26 8.2639 1.0 1417832 ChemDiv2_003648 CCOC(=O)c1sc2nc(CC(=O)OC)nc(NCC(=O)OC)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F19 compound treatment 0.274 0.0248 1.33 1.3317 1.0 1673558 ChemDiv2_003649 CC(C)OC(=O)c1c(C)oc2ccc(OC(=O)N3CCOCC3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F20 compound treatment 0.465 0.216 11.6 11.5956 1.0 1452684 ChemDiv2_003650 CCc1nc2ccccc2n1CC(O)COc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F21 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1392118 ChemDiv2_003651 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3CCN(CC3)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F22 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1270735 ChemDiv2_003652 Cn1c(=O)n(C)c2nc(Oc3ccc4OCOc4c3)n(Cc5ccc(F)cc5)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F23 mock treatment 0.253 0.00378 0.2 0.2032 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 F24 mock treatment 0.237 -0.0122 -0.66 -0.6566 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G01 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1157550 ChemDiv2_003653 C=CCn1c(NCc2ccc3OCOc3c2)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G02 compound treatment 0.275 0.0258 1.39 1.3854 1.0 1944148 ChemDiv2_003654 Cc1nnc(SCc2ccc(cc2)C(=O)O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G03 compound treatment 0.442 0.193 10.36 10.3597 1.0 1318133 ChemDiv2_003655 Fc1ccccc1C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G04 compound treatment 0.283 0.0338 1.82 1.8153 1.0 1985495 ChemDiv2_003656 CCC(Sc1nc2ccccc2s1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G05 compound treatment 0.358 0.109 5.85 5.8457 1.0 1919506 ChemDiv2_003657 CSc1nc2c(ccc3ccccc23)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G06 compound treatment 0.242 -0.00722 -0.39 -0.3879 -1.0 1571661 ChemDiv2_003658 OC(=O)CSc1nc(c([nH]1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G07 compound treatment 0.454 0.205 11.0 11.0045 1.0 1092526 ChemDiv2_003659 c1cn2cc(nc2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G08 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1985496 ChemDiv2_003660 Cc1n[nH]c(C)c1Sc2n[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G09 compound treatment 0.248 -0.00122 -0.07 -0.0655 -1.0 1651780 ChemDiv2_003661 Cc1ccc(Cn2c(SCC(O)CO)nc3n(C)c(=O)[nH]c(=O)c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G10 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1328756 ChemDiv2_003662 Nc1nc2ccccc2n1CCN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G11 compound treatment 0.31 0.0608 3.27 3.2663 1.0 1416633 ChemDiv2_003663 CCOC(=O)N1CCN(CC1)C(=O)CC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G12 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1677178 ChemDiv2_003664 CCN(CC)CCn1c(NC(=O)CC)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G13 compound treatment 0.424 0.175 9.39 9.3924 1.0 1260672 ChemDiv2_003665 CCOC(=O)Cc1csc(NC(=O)COc2c(C)cccc2C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G14 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1985497 ChemDiv2_003666 Cc1nn(c2ccc(Cl)cc2Cl)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G15 compound treatment 0.492 0.243 13.05 13.0466 1.0 1373053 ChemDiv2_003667 NS(=O)(=O)c1ccc(NC(=O)CSc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G16 compound treatment 0.473 0.224 12.03 12.0255 1.0 1211062 ChemDiv2_003668 CC(=O)Oc1cccc(c1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G17 compound treatment 0.27 0.0208 1.12 1.1167 1.0 1480638 ChemDiv2_003669 O=C(Nc1c[nH]c(=O)[nH]c1=O)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G18 compound treatment 0.302 0.0528 2.84 2.8364 1.0 1638448 ChemDiv2_003670 O=C(Nc1nc(cs1)c2ccc3OCOc3c2)c4cc5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G19 compound treatment 0.294 0.0448 2.41 2.4065 1.0 1985498 ChemDiv2_003671 Cc1noc(n1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G20 compound treatment 0.46 0.211 11.33 11.3269 1.0 1269795 ChemDiv2_003672 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4cc(=O)c5ccccc5o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G21 compound treatment 0.242 -0.00722 -0.39 -0.3879 -1.0 1985499 ChemDiv2_003673 CCC1C(=O)NC(=NC1=O)SCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G22 compound treatment 0.265 0.0158 0.85 0.8481 1.0 1328542 ChemDiv2_003674 O=C(NCC1COc2ccccc2O1)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G23 mock treatment 0.254 0.00478 0.26 0.2569 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 G24 mock treatment 0.25 7.81E-4 0.04 0.042 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H01 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1985500 ChemDiv2_003675 C(Cc1c[nH]c2ccccc12)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H02 compound treatment 0.403 0.154 8.26 8.2639 1.0 1985501 ChemDiv2_003676 O=C(CSc1ccccn1)Nc2ccc(cc2)c3ccc(NC(=O)CSc4ccccn4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H03 compound treatment 0.423 0.174 9.34 9.3386 1.0 1985502 ChemDiv2_003677 O=C(OCc1cnc(o1)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H04 compound treatment 0.362 0.113 6.06 6.0606 1.0 1412880 ChemDiv2_003678 C(Nc1ncnc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H05 compound treatment 0.271 0.0218 1.17 1.1705 1.0 1228522 ChemDiv2_003679 CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H06 compound treatment 0.352 0.103 5.52 5.5232 1.0 1249130 ChemDiv2_003680 CCCn1c2ccccc2c3nnc(SCOC(=O)CN4C(=O)c5ccccc5C4=O)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H07 compound treatment 0.389 0.14 7.51 7.5116 1.0 1660833 ChemDiv2_003681 COC(=O)COc1ccc2c(=O)c(coc2c1)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H08 compound treatment 0.522 0.273 14.66 14.6587 1.0 1677022 ChemDiv2_003682 O=C(COc1ccccc1)Nc2ccc(cc2)c3nc4ncccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H09 compound treatment 0.325 0.0758 4.07 4.0723 1.0 1160263 ChemDiv2_003683 C1CCC(CC1)Nc2nc(nc3ccccc23)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H10 compound treatment 0.296 0.0468 2.51 2.5139 1.0 1599171 ChemDiv2_003684 O=C1CCCC2=C1C(Nc3ccccc3N2)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H11 compound treatment 0.375 0.126 6.76 6.7592 1.0 1221016 ChemDiv2_003685 COc1ccc(cc1)C(NC(=O)c2ccccc2)c3ccc4cccnc4c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H12 compound treatment 0.306 0.0568 3.05 3.0513 1.0 1384204 ChemDiv2_003686 O=C(CN1C(=O)c2ccccc2C1=O)N3c4ccccc4CCc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H13 compound treatment 0.343 0.0938 5.04 5.0396 1.0 1514352 ChemDiv2_003687 CCCN1C(=O)C(Cc2nc3ccccc3c(=O)n2C)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H14 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1651359 ChemDiv2_003688 O=C1C2C3CC(C=C3)C2C(=O)N1CCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H15 compound treatment 0.452 0.203 10.9 10.897 1.0 1312208 ChemDiv2_003689 Nc1nnc(SCC(=O)N2CCc3ccccc3C2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H16 compound treatment 0.271 0.0218 1.17 1.1705 1.0 1350114 ChemDiv2_003690 CN(C)c1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H17 compound treatment 0.296 0.0468 2.51 2.5139 1.0 1523430 ChemDiv2_003691 CC1(C)Cc2ccccc2C(=N1)CSc3ccccc3C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H18 compound treatment 0.287 0.0378 2.03 2.0303 1.0 1447449 ChemDiv2_003692 CCCCN(CC)C(=O)c1sc2ncn(CC(=O)N(CC)CC)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H19 compound treatment 0.418 0.169 9.07 9.07 1.0 1171480 ChemDiv2_003693 CC(=C)COc1ccc2oc(c(C(=O)O)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H20 compound treatment 0.289 0.0398 2.14 2.1378 1.0 1302163 ChemDiv2_003694 OC(=O)CNc1nc(c2ccccc2)c3cc(Br)ccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H21 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1648808 ChemDiv2_003695 Cn1c(=O)n(C)c2ncn(Cc3ccc(F)cc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H22 compound treatment 0.248 -0.00122 -0.07 -0.0655 -1.0 1985503 ChemDiv2_003696 CCCOc1cccc(c1)C(=O)Nc2c[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H23 mock treatment 0.253 0.00378 0.2 0.2032 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 H24 mock treatment 0.243 -0.00622 -0.33 -0.3342 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I01 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1310171 ChemDiv2_003697 Cn1c(CNc2ccc(cc2)C(=O)O)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I02 compound treatment 0.461 0.212 11.38 11.3807 1.0 1402934 ChemDiv2_003698 COc1ccc2[nH]c(SCC(=O)c3ccc4OCOc4c3)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I03 compound treatment 0.284 0.0348 1.87 1.8691 1.0 1985504 ChemDiv2_003699 CC(=C)c1nc2ccccc2c(=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I04 compound treatment 0.276 0.0268 1.44 1.4392 1.0 1246016 ChemDiv2_003700 CCN(CC)C(=O)c1sc2nc(C)cc(C)c2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I05 compound treatment 0.333 0.0838 4.5 4.5022 1.0 1985505 ChemDiv2_003701 COc1nnc(Cl)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I06 compound treatment 0.311 0.0618 3.32 3.32 1.0 1985506 ChemDiv2_003702 CCOc1ccc(Nc2nc(Cl)nc(NCC=C)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I07 compound treatment 0.24 -0.00922 -0.5 -0.4954 -1.0 1594743 ChemDiv2_003703 Cn1c(NCC=C)nc2n(C)c(=O)[nH]c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I08 compound treatment 0.268 0.0188 1.01 1.0093 1.0 1985507 ChemDiv2_003704 Cn1c(=O)n(C)c2nc(NCC3CCCO3)n(Cc4ccc(Cl)cc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I09 compound treatment 0.239 -0.0102 -0.55 -0.5491 -1.0 1945711 ChemDiv2_003705 CCN(CC)CCSc1nc(O)c(CC)c(=O)n1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I10 compound treatment 0.253 0.00378 0.2 0.2032 1.0 1217164 ChemDiv2_003706 Nc1nc2ccccc2n1CCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I11 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1306044 ChemDiv2_003707 OCCN1C(=O)c2ccccc2C1(O)c3ncc[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I12 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1517877 ChemDiv2_003708 Cc1ccc(Cn2c(NC(=O)c3cccs3)nc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I13 compound treatment 0.304 0.0548 2.94 2.9438 1.0 1405523 ChemDiv2_003709 CC(C)N(Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I14 compound treatment 0.286 0.0368 1.98 1.9765 1.0 1674829 ChemDiv2_003710 CN(C)C(=O)Cn1nc(C)c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I15 compound treatment 0.537 0.288 15.46 15.4648 1.0 1592972 ChemDiv2_003711 CSc1nc2ccccc2n1CCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I16 compound treatment 0.272 0.0228 1.22 1.2242 1.0 1985508 ChemDiv2_003712 C=CCn1c2ncnn2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I17 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1341879 ChemDiv2_003713 O=C(Cc1ccccc1)Nc2c[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I18 compound treatment 0.418 0.169 9.07 9.07 1.0 1260052 ChemDiv2_003714 CC1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I19 compound treatment 0.271 0.0218 1.17 1.1705 1.0 1610987 ChemDiv2_003715 COC(=O)c1ccc(cc1)n2c(C)nc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I20 compound treatment 0.444 0.195 10.47 10.4671 1.0 1662741 ChemDiv2_003716 CCOC(=O)c1sc2ccccc2c1NC(=O)c3coc4ccccc4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I21 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1030466 ChemDiv2_003717 CCN(CC)CCSc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I22 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1598232 ChemDiv2_003718 OCCNc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I23 mock treatment 0.253 0.00378 0.2 0.2032 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 I24 mock treatment 0.248 -0.00122 -0.07 -0.0655 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J01 compound treatment 0.248 -0.00122 -0.07 -0.0655 -1.0 1586604 ChemDiv2_003719 CC(C)NCCc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J02 compound treatment 0.345 0.0958 5.15 5.1471 1.0 1646746 ChemDiv2_003720 Oc1ccc(cc1)n2c(nc3ccccc3c2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J03 compound treatment 0.381 0.132 7.08 7.0816 1.0 1985509 ChemDiv2_003721 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J04 compound treatment 0.301 0.0518 2.78 2.7826 1.0 1509059 ChemDiv2_003722 Cc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J05 compound treatment 0.386 0.137 7.35 7.3503 1.0 1500678 ChemDiv2_003723 O=C(CSc1nc2ccccc2o1)NC(=O)CSc3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J06 compound treatment 0.353 0.104 5.58 5.577 1.0 1579030 ChemDiv2_003724 C(CN1CCOCC1)Sc2nnc3c4ccccc4n(CCc5ccccc5)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J07 compound treatment 0.267 0.0178 0.96 0.9555 1.0 1285901 ChemDiv2_003725 CCN(CC)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J08 compound treatment 0.273 0.0238 1.28 1.278 1.0 1722301 ChemDiv2_003726 OC(=O)CCSc1nc2ccccc2n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J09 compound treatment 0.284 0.0348 1.87 1.8691 1.0 1985510 ChemDiv2_003727 COc1nc(nc2ccccc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J10 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1256759 ChemDiv2_003728 CCC(=O)N1C(C2=C(CCCC2=O)Nc3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J11 compound treatment 0.264 0.0148 0.79 0.7943 1.0 1544625 ChemDiv2_003729 COc1ccc(cc1OC)C(NC(=O)C(C)C)c2ccc3cccnc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J12 compound treatment 0.292 0.0428 2.3 2.299 1.0 1471874 ChemDiv2_003730 CC1=CC(C)(C)Nc2ccc(OC(=O)CN3C(=O)CCC3=O)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J13 compound treatment 0.294 0.0448 2.41 2.4065 1.0 1274056 ChemDiv2_003731 CC(C)Cc1cc(c2ccco2)c(C#N)c(NC(=O)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J14 compound treatment 0.365 0.116 6.22 6.2218 1.0 1642129 ChemDiv2_003732 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccncc4)ccc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J15 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1261161 ChemDiv2_003733 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccco4)C(=O)C5CC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J16 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1402608 ChemDiv2_003734 CC(=O)NCC1OCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J17 compound treatment 0.277 0.0278 1.49 1.4929 1.0 1287279 ChemDiv2_003735 COc1cc2CC3(CCCC3)n4c(C)nnc4-c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J18 compound treatment 0.245 -0.00422 -0.23 -0.2267 -1.0 1284539 ChemDiv2_003736 Cc1sc2ncn(CC(=O)NCC(=O)O)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J19 compound treatment 0.49 0.241 12.94 12.9391 1.0 1386115 ChemDiv2_003737 CCOC(=O)COc1ccc2cc(c3nc4ccccc4[nH]3)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J20 compound treatment 0.584 0.335 17.99 17.9904 1.0 1606578 ChemDiv2_003738 COc1ccc(NC(=O)CCSc2nc3ccccc3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J21 compound treatment 0.253 0.00378 0.2 0.2032 1.0 1449803 ChemDiv2_003739 Cc1ccc2n3CCN(CCC#N)C4CCCc(c43)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J22 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1781477 ChemDiv2_003740 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3c[nH]c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J23 mock treatment 0.252 0.00278 0.15 0.1495 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 J24 mock treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K01 compound treatment 0.269 0.0198 1.06 1.063 1.0 1985511 ChemDiv2_003741 CN(C(=O)c1nc[nH]n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K02 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1391868 ChemDiv2_003742 COc1cc(CNc2nc3ccccc3[nH]2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K03 compound treatment 0.33 0.0808 4.34 4.341 1.0 1280356 ChemDiv2_003743 CCCOc1ccc(cc1)c2nc(N)n[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K04 compound treatment 0.252 0.00278 0.15 0.1495 1.0 1985512 ChemDiv2_003744 COC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K05 compound treatment 0.265 0.0158 0.85 0.8481 1.0 1166877 ChemDiv2_003745 CSc1nsc(SC)c1NC(=O)OC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K06 compound treatment 0.307 0.0578 3.11 3.105 1.0 1505337 ChemDiv2_003746 CS(=O)(=O)N1CCN(CC(O)Cn2c3ccccc3c4ccccc24)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K07 compound treatment 0.259 0.00978 0.53 0.5256 1.0 1402712 ChemDiv2_003747 CCn1c(nc2n(C)c(=O)[nH]c(=O)c12)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K08 compound treatment 0.303 0.0538 2.89 2.8901 1.0 1569509 ChemDiv2_003748 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4ccccc4F)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K09 compound treatment 0.248 -0.00122 -0.07 -0.0655 -1.0 1783822 ChemDiv2_003749 CCN(CC)CCSc1nc(O)c(C2CCCCC2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K10 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1601163 ChemDiv2_003750 Cn1c(=N)n(CC(O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K11 compound treatment 0.375 0.126 6.76 6.7592 1.0 1428781 ChemDiv2_003751 C(Sc1nnc2c3ccccc3[nH]c2n1)C4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K12 compound treatment 0.459 0.21 11.27 11.2732 1.0 1587696 ChemDiv2_003752 CCc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K13 compound treatment 0.272 0.0228 1.22 1.2242 1.0 1525172 ChemDiv2_003753 CCN(CC)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K14 compound treatment 0.268 0.0188 1.01 1.0093 1.0 1590784 ChemDiv2_003754 Oc1ccc(NC(=O)Cn2nc(c3ccccc3)c4ccccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K15 compound treatment 0.25 7.81E-4 0.04 0.042 1.0 1316920 ChemDiv2_003755 CCOC(=O)c1c(CN(CC)CC)n(C)c2cc(Br)c(OC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K16 compound treatment 0.283 0.0338 1.82 1.8153 1.0 1985513 ChemDiv2_003756 Cn1c(NC(=N)c2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K17 compound treatment 0.525 0.276 14.82 14.8199 1.0 1660106 ChemDiv2_003757 O=C(Nc1nccs1)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K18 compound treatment 0.527 0.278 14.93 14.9274 1.0 1448867 ChemDiv2_003758 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)N5C(=O)CCC5=O)sc32)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K19 compound treatment 0.259 0.00978 0.53 0.5256 1.0 1985514 ChemDiv2_003759 COc1nc(NC(=O)C)nc(C)c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K20 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1661172 ChemDiv2_003760 Cn1c(=O)n(C)c2nc(NCCO)n(Cc3ccc(F)cc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K21 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1249651 ChemDiv2_003761 Cc1ccc(cc1NC(=O)c2ccc3OCCOc3c2)c4nc5ccccc5s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K22 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1985515 ChemDiv2_003762 COC(=O)C(C)N(C#N)c1nc(C)cc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K23 mock treatment 0.245 -0.00422 -0.23 -0.2267 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 K24 mock treatment 0.257 0.00778 0.42 0.4181 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L01 compound treatment 0.246 -0.00322 -0.17 -0.173 -1.0 1525834 ChemDiv2_003763 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4Sc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L02 compound treatment 0.318 0.0688 3.7 3.6962 1.0 1372259 ChemDiv2_003764 Oc1cccc(c1)n2c(nc3ccccc3c2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L03 compound treatment 0.264 0.0148 0.79 0.7943 1.0 1119977 ChemDiv2_003765 Cc1nn(c2cccc(c2)C(=O)O)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L04 compound treatment 0.263 0.0138 0.74 0.7406 1.0 1682266 ChemDiv2_003766 O=C(CN1C(=O)c2ccccc2C1=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L05 compound treatment 0.349 0.0998 5.36 5.362 1.0 1695161 ChemDiv2_003767 Cn1c(SCC(=O)Nc2ccccc2Oc3ccccc3)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L06 compound treatment 0.231 -0.0182 -0.98 -0.979 -1.0 1668224 ChemDiv2_003768 C(NC(Cc1ccccc1)c2ccccc2)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L07 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1332500 ChemDiv2_003769 CCCCN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L08 compound treatment 0.312 0.0628 3.37 3.3737 1.0 1577473 ChemDiv2_003770 COc1ccc(NC(=O)Cn2c(nc3ccccc23)c4cscn4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L09 compound treatment 0.395 0.146 7.83 7.834 1.0 1932196 ChemDiv2_003771 CCn1c(SCC(=O)c2ccccc2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L10 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1190368 ChemDiv2_003772 O=C(N1C(C2=C(CCCC2=O)Nc3ccccc13)c4ccco4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L11 compound treatment 0.293 0.0438 2.35 2.3527 1.0 1173633 ChemDiv2_003773 Oc1c(ccc2cccnc12)C(NC(=O)c3ccccc3)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L12 compound treatment 0.36 0.111 5.95 5.9532 1.0 1619780 ChemDiv2_003774 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4ccc(O)c(O)c4)C(=O)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L13 compound treatment 0.449 0.2 10.74 10.7358 1.0 1668288 ChemDiv2_003775 CCOC(=O)C(C1CCCCC1)C(=O)Nc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L14 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1207293 ChemDiv2_003776 CC(C)(C)C1CCC(CC1)OC(=O)CCC(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L15 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1985516 ChemDiv2_003777 COC(=O)C1=CNC=C(C1c2ccc(C)s2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L16 compound treatment 0.259 0.00978 0.53 0.5256 1.0 1154571 ChemDiv2_003778 CNC(=O)CC1Sc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L17 compound treatment 0.253 0.00378 0.2 0.2032 1.0 1605114 ChemDiv2_003779 C1CCC2(CC1)Cc3ccccc3-c4nnc(c5cccnc5)n42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L18 compound treatment 0.368 0.119 6.38 6.3831 1.0 1728037 ChemDiv2_003780 CCOC(=O)c1sc2ncnc(N3CCc4ccccc4C3)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L19 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1134290 ChemDiv2_003781 CC1CCCN(Cc2c(O)ccc3c(=O)c(c4nc5ccccc5s4)c(C)oc23)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L20 compound treatment 0.277 0.0278 1.49 1.4929 1.0 1285086 ChemDiv2_003782 CN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L21 compound treatment 0.259 0.00978 0.53 0.5256 1.0 1116168 ChemDiv2_003783 Cn1c(=O)n(C)c2ncn(CC=C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L22 compound treatment 0.311 0.0618 3.32 3.32 1.0 1522786 ChemDiv2_003784 O=C1CCC(=O)N1c2ccc(cc2)c3nc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L23 mock treatment 0.246 -0.00322 -0.17 -0.173 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 L24 mock treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M01 compound treatment 0.296 0.0468 2.51 2.5139 1.0 1247577 ChemDiv2_003785 O=C(COc1ccc2c(=O)c(coc2c1)c3ccccc3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M02 compound treatment 0.236 -0.0132 -0.71 -0.7103 -1.0 1274952 ChemDiv2_003786 O=C1N(Cc2nc3ccccc3c(=O)n2c4ccncc4)C(=O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M03 compound treatment 0.307 0.0578 3.11 3.105 1.0 1652071 ChemDiv2_003787 Clc1ccc(OC(C(=O)c2ccc(Cl)cc2)n3cncn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M04 compound treatment 0.267 0.0178 0.96 0.9555 1.0 1611104 ChemDiv2_003788 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(C#N)c(Cl)c3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M05 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1261321 ChemDiv2_003789 COc1ccc(Cl)cc1S(=O)(=O)n2ccnc2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M06 compound treatment 0.35 0.101 5.42 5.4158 1.0 1507411 ChemDiv2_003790 CS(=O)(=O)N(CC(O)Cn1c2ccccc2c3ccccc13)Cc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M07 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1708969 ChemDiv2_003791 Cn1c(SCC(=O)c2ccccc2)nc3n(C)c(=O)[nH]c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M08 compound treatment 0.266 0.0168 0.9 0.9018 1.0 1362523 ChemDiv2_003792 CC(CCO)Nc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccccc3Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M09 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1560195 ChemDiv2_003793 CN(C)CCSc1nc(O)c(c2ccccc2)c(=O)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M10 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1738517 ChemDiv2_003794 CC(O)Cn1c(=N)n(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M11 compound treatment 0.309 0.0598 3.21 3.2125 1.0 1485737 ChemDiv2_003795 C(CN1CCCCC1)Sc2nnc3c4ccccc4[nH]c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M12 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1174008 ChemDiv2_003796 O=S(=O)(Cc1ccccc1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M13 compound treatment 0.28 0.0308 1.65 1.6541 1.0 1673829 ChemDiv2_003797 CN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M14 compound treatment 0.445 0.196 10.52 10.5209 1.0 1524792 ChemDiv2_003798 OC(=O)CCC(=O)Nc1ccc(cc1)c2nc3cc(NC(=O)CCC(=O)O)ccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M15 compound treatment 0.27 0.0208 1.12 1.1167 1.0 1985517 ChemDiv2_003799 Cc1cc(C)nc(SC/C(=N\O)/N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M16 compound treatment 0.51 0.261 14.01 14.0138 1.0 1606282 ChemDiv2_003800 Cc1sc2nc(SCC(=O)N3CCCC3)[nH]c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M17 compound treatment 0.267 0.0178 0.96 0.9555 1.0 1426057 ChemDiv2_003801 O=c1[nH]cc(n2c(=O)c3ccccc3c4ccccc4c2=O)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M18 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1428395 ChemDiv2_003802 COC(=O)c1sc2ccccc2c1NC(=O)c3ccc(cc3)N4C(=O)CCC4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M19 compound treatment 0.249 -2.19E-4 -0.01 -0.0118 -1.0 1256333 ChemDiv2_003803 COc1cc(C)nc(n1)N(C)S(=O)(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M20 compound treatment 0.261 0.0118 0.63 0.6331 1.0 1461325 ChemDiv2_003804 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M21 compound treatment 0.263 0.0138 0.74 0.7406 1.0 1985518 ChemDiv2_003805 ClC1=CCC2C(C1)C(=O)N(CC(=O)Nc3sc4CCCc4c3C#N)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M22 compound treatment 0.271 0.0218 1.17 1.1705 1.0 1985519 ChemDiv2_003806 CC(C)Nc1nc(NC(C)C)nc(n1)N(C)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M23 mock treatment 0.249 -2.19E-4 -0.01 -0.0118 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 M24 mock treatment 0.254 0.00478 0.26 0.2569 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N01 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1985520 ChemDiv2_003807 Oc1nc2cc(Cl)ccc2c(c1Sc3nnc[nH]3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N02 compound treatment 0.261 0.0118 0.63 0.6331 1.0 1137093 ChemDiv2_003808 Oc1ccccc1n2c(nc3ccccc3c2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N03 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1590333 ChemDiv2_003809 Cc1nn(c2ccccc2C(=O)O)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N04 compound treatment 0.29 0.0408 2.19 2.1915 1.0 1528365 ChemDiv2_003810 CCC(CC)c1nc2cc(OC)c(OC)cc2c(=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N05 compound treatment 0.269 0.0198 1.06 1.063 1.0 1389197 ChemDiv2_003811 NC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N06 compound treatment 0.283 0.0338 1.82 1.8153 1.0 1985521 ChemDiv2_003812 Cc1ccc(NC(=O)CSc2nccn2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N07 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1242910 ChemDiv2_003813 Cc1nc2ccccc2c(O)c1CN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N08 compound treatment 0.546 0.297 15.95 15.9484 1.0 1205134 ChemDiv2_003814 COc1ccc(cc1)c2nc(SCC=C)n(CC=C)c(=O)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N09 compound treatment 0.344 0.0948 5.09 5.0933 1.0 1448790 ChemDiv2_003815 CSc1nc2sc-3c(CCc4ccccc34)c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N10 compound treatment 0.303 0.0538 2.89 2.8901 1.0 1246434 ChemDiv2_003816 CCOC(=O)C(CC)Oc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N11 compound treatment 0.299 0.0498 2.68 2.6751 1.0 1935835 ChemDiv2_003817 CCn1c2C(=O)CCCc2c3cc(C)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N12 compound treatment 0.289 0.0398 2.14 2.1378 1.0 1166230 ChemDiv2_003818 O=C(CSc1nnc[nH]1)N2c3ccccc3CCc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N13 compound treatment 0.306 0.0568 3.05 3.0513 1.0 1002464 ChemDiv2_003819 CC(C)Nc1ncnc2n(ncc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N14 compound treatment 0.247 -0.00222 -0.12 -0.1192 -1.0 1309191 ChemDiv2_003820 Nc1nc2CCCCCc2c(c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N15 compound treatment 0.253 0.00378 0.2 0.2032 1.0 1985522 ChemDiv2_003821 Cn1c(Cn2ccnc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N16 compound treatment 0.251 0.00178 0.1 0.0957 1.0 1713545 ChemDiv2_003822 CC(=O)Oc1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(F)cc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N17 compound treatment 0.457 0.208 11.17 11.1657 1.0 1447756 ChemDiv2_003823 CCN(CC)C(=O)c1ccc2nc(NC(=O)c3ccc(OC(=O)C)cc3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N18 compound treatment 0.24 -0.00922 -0.5 -0.4954 -1.0 1985523 ChemDiv2_003824 Clc1ccc(cc1)n2nc(C(=O)Nc3cccc(Cl)c3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N19 compound treatment 0.248 -0.00122 -0.07 -0.0655 -1.0 1699139 ChemDiv2_003825 COC(=O)c1c(C)oc2cc(Br)c(OC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N20 compound treatment 0.25 7.81E-4 0.04 0.042 1.0 1602961 ChemDiv2_003826 C=CCN(CC=C)Cc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N21 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1430085 ChemDiv2_003827 Cc1cc2nn(nc2cc1NC(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N22 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1124306 ChemDiv2_003828 O=c1n(CC2CCCO2)c(=O)c3ccccc3c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N23 mock treatment 0.256 0.00678 0.36 0.3644 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 N24 mock treatment 0.242 -0.00722 -0.39 -0.3879 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O01 compound treatment 0.258 0.00878 0.47 0.4719 1.0 1249595 ChemDiv2_003829 COC(=O)c1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(OC)cc4OC)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O02 compound treatment 0.313 0.0638 3.43 3.4275 1.0 1579499 ChemDiv2_003830 Cc1cccnc1n2c(CCN3C(=O)c4ccccc4C3=O)nc5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O03 compound treatment 0.267 0.0178 0.96 0.9555 1.0 1985524 ChemDiv2_003831 Brc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O04 compound treatment 0.246 -0.00322 -0.17 -0.173 -1.0 1214662 ChemDiv2_003832 CC(=O)NS(=O)(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O05 compound treatment 0.283 0.0338 1.82 1.8153 1.0 1411065 ChemDiv2_003833 CC(=O)Nc1nc(CC(=O)O)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O06 compound treatment 0.298 0.0488 2.62 2.6214 1.0 1686502 ChemDiv2_003834 CC(c1nnc(NC(=O)c2ccc3OCOc3c2)s1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O07 compound treatment 0.253 0.00378 0.2 0.2032 1.0 1295273 ChemDiv2_003835 CC(C)Cn1c(nc2n(C)c(=O)[nH]c(=O)c12)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O08 compound treatment 0.487 0.238 12.78 12.7779 1.0 1109371 ChemDiv2_003836 Cn1c(NCCc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O09 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1985525 ChemDiv2_003837 Clc1ccccc1c2nc(no2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O10 compound treatment 0.257 0.00778 0.42 0.4181 1.0 1576029 ChemDiv2_003838 CCn1c(=N)n(CC(O)c2cccs2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O11 compound treatment 0.471 0.222 11.92 11.9181 1.0 1211212 ChemDiv2_003839 CCn1c2ccccc2c3nnc(SCN4C(=O)c5ccccc5C4=O)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O12 compound treatment 0.267 0.0178 0.96 0.9555 1.0 1210332 ChemDiv2_003840 CC(C)(C)C(=O)Cn1c(=N)n(CC=C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O13 compound treatment 0.259 0.00978 0.53 0.5256 1.0 1721613 ChemDiv2_003841 CC1(C)Cc2c(sc3ncn4nc(nc4c23)c5ccncc5)C(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O14 compound treatment 0.246 -0.00322 -0.17 -0.173 -1.0 1248335 ChemDiv2_003842 CC(=O)OCCn1c(=O)c2cc3c(=O)n(CCOC(=O)C)c(=O)c3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O15 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1398101 ChemDiv2_003843 COc1ccc(CN2CCN(CC2)C(=O)CC(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O16 compound treatment 0.252 0.00278 0.15 0.1495 1.0 1669303 ChemDiv2_003844 CC(C)CSc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O17 compound treatment 0.252 0.00278 0.15 0.1495 1.0 1528874 ChemDiv2_003845 Cc1cc(C)nc(Nc2ncc(O)n2c3ccc(C)c(C)c3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O18 compound treatment 0.496 0.247 13.26 13.2615 1.0 1401181 ChemDiv2_003846 O=C(Nc1cccc(c1)c2nc3ccccc3[nH]2)c4cccc(c4)N5C(=O)CCC5=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O19 compound treatment 0.256 0.00678 0.36 0.3644 1.0 1985526 ChemDiv2_003847 CN(C)c1nc(OCCOC(=O)C)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O20 compound treatment 0.279 0.0298 1.6 1.6004 1.0 1169554 ChemDiv2_003848 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=O)[nH]c(=O)c3C2c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O21 compound treatment 0.327 0.0778 4.18 4.1798 1.0 1654469 ChemDiv2_003849 CCCC(=O)Nc1nnc(s1)c2cccc(OCC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O22 compound treatment 0.266 0.0168 0.9 0.9018 1.0 1464046 ChemDiv2_003850 CC(C)(C)C(=O)Nc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O23 mock treatment 0.251 0.00178 0.1 0.0957 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 O24 mock treatment 0.256 0.00678 0.36 0.3644 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P01 compound treatment 0.416 0.167 8.96 8.9625 1.0 1601526 ChemDiv2_003851 Cc1cc(NC(=O)CSc2ccccn2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P02 compound treatment 0.294 0.0448 2.41 2.4065 1.0 1985527 ChemDiv2_003852 CCOC(=O)c1cnc2ccccc2c1NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P03 compound treatment 0.259 0.00978 0.53 0.5256 1.0 1170375 ChemDiv2_003853 Brc1ccc2[nH]c(=O)c(NC(=O)CNS(=O)(=O)c3ccccc3)c(c4ccccc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P04 compound treatment 0.335 0.0858 4.61 4.6097 1.0 1429901 ChemDiv2_003854 Cc1cccc(NC(=O)CSc2nsc(SCC(=O)Nc3cccc(C)c3)n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P05 compound treatment 0.279 0.0298 1.6 1.6004 1.0 1109378 ChemDiv2_003855 c1ccc(cc1)c2noc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P06 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1852059 ChemDiv2_003856 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3Cl)C(=O)Nc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P07 compound treatment 0.254 0.00478 0.26 0.2569 1.0 1404602 ChemDiv2_003857 CCN1CCN(Cc2c(C)nc3ccc(C)cc3c2O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P08 compound treatment 0.272 0.0228 1.22 1.2242 1.0 1550131 ChemDiv2_003858 OC(CN1C(=O)c2ccccc2S1(=O)=O)CN3c4ccccc4Sc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P09 compound treatment 0.286 0.0368 1.98 1.9765 1.0 1433402 ChemDiv2_003859 COC(=O)c1[nH]c2CCCC(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P10 compound treatment 0.244 -0.00522 -0.28 -0.2804 -1.0 1350186 ChemDiv2_003860 CC(C)OC(=O)COc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P11 compound treatment 0.26 0.0108 0.58 0.5794 1.0 1223281 ChemDiv2_003861 CCn1c2C(=O)CCCc2c3cc(ccc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P12 compound treatment 0.193 -0.0562 -3.02 -3.0211 -1.0 1590353 ChemDiv2_003862 Cc1nccn1CC(=O)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P13 compound treatment 0.262 0.0128 0.69 0.6868 1.0 1528981 ChemDiv2_003863 COc1ccc(Nc2ncnc3n(ncc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P14 compound treatment 0.277 0.0278 1.49 1.4929 1.0 1494576 ChemDiv2_003864 CC(C)c1ccc(cc1)c2c3CCCc3nc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P15 compound treatment 0.448 0.199 10.68 10.6821 1.0 1619071 ChemDiv2_003865 COc1ccc(Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P16 compound treatment 0.236 -0.0132 -0.71 -0.7103 -1.0 1599355 ChemDiv2_003866 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc(Oc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P17 compound treatment 0.303 0.0538 2.89 2.8901 1.0 1678180 ChemDiv2_003867 CC1CCCN(Cc2c(O)ccc3cc(c4nc5ccccc5[nH]4)c(=O)oc23)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P18 compound treatment 0.249 -2.19E-4 -0.01 -0.0118 -1.0 1985528 ChemDiv2_003868 CCn1c(C(=O)O)c(CC(=O)Nc2ccccc2OC)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P19 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1693929 ChemDiv2_003869 CCN(CC)CC(O)Cn1c(C)c(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P20 compound treatment 0.255 0.00578 0.31 0.3107 1.0 1485807 ChemDiv2_003870 CN(C)C(=O)c1cc(nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P21 compound treatment 0.417 0.168 9.02 9.0162 1.0 1734260 ChemDiv2_003871 Fc1ccc(cc1)c2ccc(o2)C(=O)Nc3ccc4oc(nc4c3)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P22 compound treatment 0.486 0.237 12.72 12.7241 1.0 1398066 ChemDiv2_003872 CSc1nnc(SCc2nc3ccccc3[nH]2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P23 mock treatment 0.258 0.00878 0.47 0.4719 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1379 P24 mock treatment 0.242 -0.00722 -0.39 -0.3879 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A01 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1985529 ChemDiv2_003873 OCCN1C(=O)C2CC=C(Cl)CC2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A02 compound treatment 0.241 -0.012 -0.64 -0.6432 -1.0 1985530 ChemDiv2_003874 COC(=O)CNc1nc(Cl)nc(Nc2ccc(I)cc2C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A03 compound treatment 0.25 -0.00297 -0.16 -0.1595 -1.0 1787243 ChemDiv2_003875 CCn1c(NCc2nc3ccccc3n2C)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A04 compound treatment 0.237 -0.016 -0.86 -0.8581 -1.0 1278506 ChemDiv2_003876 CSc1nc2ccccc2c(=O)n1C3CCOC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A05 compound treatment 0.552 0.299 16.07 16.0693 1.0 1585132 ChemDiv2_003877 COC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A06 compound treatment 0.252 -9.69E-4 -0.05 -0.0521 -1.0 1348462 ChemDiv2_003878 CNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A07 compound treatment 0.54 0.287 15.42 15.4245 1.0 1676456 ChemDiv2_003879 CCOc1ccc(cc1)c2cc(=O)c3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A08 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1147108 ChemDiv2_003880 CN(C)CCOc1nc(nc2c3ccccc3oc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A09 compound treatment 0.295 0.042 2.26 2.2587 1.0 1852741 ChemDiv2_003881 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccccc4)C(=O)Nc5ccccc5F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A10 compound treatment 0.241 -0.012 -0.64 -0.6432 -1.0 1788959 ChemDiv2_003882 CCCCn1c(SCC(=O)N)nc2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A11 compound treatment 0.473 0.22 11.82 11.824 1.0 1940697 ChemDiv2_003883 CSc1nnc2sc3ccccc3n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A12 compound treatment 0.334 0.081 4.35 4.3544 1.0 1189819 ChemDiv2_003884 CN1C(=O)C(Cc2nc3ccccc3c(=O)n2c4ccccc4)c5cc(Br)ccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A13 compound treatment 0.248 -0.00497 -0.27 -0.267 -1.0 1985531 ChemDiv2_003885 CCC(C)C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A14 compound treatment 0.34 0.087 4.68 4.6769 1.0 1677801 ChemDiv2_003886 CN(Cc1ccccc1)c2ncnc3ccc(Br)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A15 compound treatment 0.339 0.086 4.62 4.6231 1.0 1183872 ChemDiv2_003887 Cc1nnc(NC(=O)C2c3ccccc3Oc4ccccc24)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A16 compound treatment 0.437 0.184 9.89 9.8895 1.0 1467768 ChemDiv2_003888 Cc1ccc2nc(SCc3nc4ccccc4n3C)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A17 compound treatment 0.343 0.09 4.84 4.8381 1.0 1596259 ChemDiv2_003889 COc1ccc(OCC(=O)OCCN2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A18 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1585824 ChemDiv2_003890 COc1ccc(C2N(CCCN(C)C)C(=O)C(=C2C(=O)c3cccs3)O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A19 compound treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1180824 ChemDiv2_003891 CC(C)CNc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A20 compound treatment 0.286 0.033 1.78 1.775 1.0 1421738 ChemDiv2_003892 COc1ccc2oc(c(C(=O)O)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A21 compound treatment 0.238 -0.015 -0.8 -0.8044 -1.0 1388493 ChemDiv2_003893 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A22 compound treatment 0.247 -0.00597 -0.32 -0.3207 -1.0 1134604 ChemDiv2_003894 CCOc1ccc2nc(C)c(CN(CC=C)CC=C)c(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A23 mock treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 A24 mock treatment 0.266 0.013 0.7 0.7003 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B01 compound treatment 0.256 0.00303 0.16 0.1629 1.0 1985532 ChemDiv2_003895 CCS(=O)(=O)CCSc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B02 compound treatment 0.272 0.019 1.02 1.0227 1.0 1985533 ChemDiv2_003896 Cc1csc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B03 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1407872 ChemDiv2_003897 COc1ccc(cc1)C(=O)c2c(C)c3ccccc3n2CC(O)CNC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B04 compound treatment 0.256 0.00303 0.16 0.1629 1.0 1412975 ChemDiv2_003898 O=C(Cc1ccccc1)NCC2OCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B05 compound treatment 0.245 -0.00797 -0.43 -0.4282 -1.0 1462746 ChemDiv2_003899 Cc1cccc(n1)N2C(=O)c3cccc4cccc(C2=O)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B06 compound treatment 0.274 0.021 1.13 1.1302 1.0 1364030 ChemDiv2_003900 CCOC(=O)N1CCN(CC1)C(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B07 compound treatment 0.452 0.199 10.7 10.6955 1.0 1507536 ChemDiv2_003901 Cc1cccc(c1)C2C3C(=O)c4ccccc4C3=Nc5c2c(=O)n(C)c(=O)n5C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B08 compound treatment 0.319 0.066 3.55 3.5484 1.0 1378763 ChemDiv2_003902 Cc1nc2ccccc2c3nc(NC(=O)c4ccc5nsnc5c4)nn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B09 compound treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1681748 ChemDiv2_003903 Cc1nnc(NC2CCCCC2)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B10 compound treatment 0.253 3.12E-5 0.0 0.0017 1.0 1246768 ChemDiv2_003904 Cc1ccc(cc1)N2CC(CC2=O)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B11 compound treatment 0.293 0.04 2.15 2.1512 1.0 1145131 ChemDiv2_003905 Oc1ccccc1c2nc(N3CCCCC3)c4ccccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B12 compound treatment 0.264 0.011 0.59 0.5928 1.0 1985534 ChemDiv2_003906 CC(C)c1nnc2c3c4CCCCc4sc3ncn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B13 compound treatment 0.517 0.264 14.19 14.1885 1.0 1618238 ChemDiv2_003907 CC(C)(C)c1ccc(cc1)c2nc(no2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B14 compound treatment 0.47 0.217 11.66 11.6628 1.0 1461551 ChemDiv2_003908 CC(C)COC(=O)COc1ccc2c(=O)c(coc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B15 compound treatment 0.3 0.047 2.53 2.5274 1.0 1433715 ChemDiv2_003909 CCOC(=O)c1c(C)oc2c1c(C(N3CCOCC3)c4cccnc4)c(O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B16 compound treatment 0.505 0.252 13.54 13.5436 1.0 1744845 ChemDiv2_003910 C(Sc1nnc(c2ccco2)c(n1)c3ccco3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B17 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1519762 ChemDiv2_003911 CC1CCCCN1Cc2c(O)ccc3cc(c4nc5ccccc5n4C)c(=O)oc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B18 compound treatment 0.253 3.12E-5 0.0 0.0017 1.0 1702985 ChemDiv2_003912 CCCN(CCC)c1nc(Cl)nc(NCCN2CCOCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B19 compound treatment 0.28 0.027 1.45 1.4526 1.0 1788904 ChemDiv2_003913 CCOc1cc(ccc1O)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B20 compound treatment 0.389 0.136 7.31 7.31 1.0 1985535 ChemDiv2_003914 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4nc(cs4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B21 compound treatment 0.523 0.27 14.51 14.5109 1.0 1985536 ChemDiv2_003915 CCc1c(C)c2c(C)n[nH]c2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B22 compound treatment 0.262 0.00903 0.49 0.4853 1.0 988 ChemDiv2_003916 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B23 mock treatment 0.242 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 B24 mock treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C01 compound treatment 0.304 0.051 2.74 2.7423 1.0 1447858 ChemDiv2_003917 OC1(Cc2ccccc2)N(C(=O)c3ccccc31)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C02 compound treatment 0.248 -0.00497 -0.27 -0.267 -1.0 1985537 ChemDiv2_003918 Cn1c(Sc2nc3ccccc3n2CC(=O)NC4CCCCC4)nc5n(C)c(=O)n(C)c(=O)c15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C03 compound treatment 0.273 0.02 1.08 1.0764 1.0 1211055 ChemDiv2_003919 COC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C04 compound treatment 0.284 0.031 1.67 1.6676 1.0 1710707 ChemDiv2_003920 CCn1c(SCC(=O)N)nc2-c3ccccc3CC4(CCCCC4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C05 compound treatment 0.258 0.00503 0.27 0.2704 1.0 1985538 ChemDiv2_003921 Cc1nnc(SCC(=O)O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C06 compound treatment 0.278 0.025 1.35 1.3451 1.0 1700221 ChemDiv2_003922 Cn1c(=O)[nH]c(=O)c2n(CCCc3ccccc3)c(nc12)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C07 compound treatment 0.446 0.193 10.37 10.3731 1.0 1018152 ChemDiv2_003923 Oc1ccc(cc1)c2cc(=O)c3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C08 compound treatment 0.463 0.21 11.29 11.2866 1.0 1985539 ChemDiv2_003924 O=c1n(c(CSc2ncnc3ccccc23)nc4ccccc14)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C09 compound treatment 0.259 0.00603 0.32 0.3241 1.0 1389664 ChemDiv2_003925 Cc1cc(C)n(n1)C(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C10 compound treatment 0.299 0.046 2.47 2.4736 1.0 1607669 ChemDiv2_003926 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3CN(C(=O)C3)c4ccccc4)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C11 compound treatment 0.422 0.169 9.08 9.0834 1.0 1370661 ChemDiv2_003927 OCCNc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C12 compound treatment 0.305 0.052 2.8 2.7961 1.0 1931121 ChemDiv2_003928 CCOc1ccc(CSc2nnc[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C13 compound treatment 0.262 0.00903 0.49 0.4853 1.0 1741267 ChemDiv2_003929 CCSC1=C(C#N)C2(CCN(C)CC2)C(C#N)C(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C14 compound treatment 0.279 0.026 1.4 1.3989 1.0 1194253 ChemDiv2_003930 CCN1CCN(CC1)c2ncnc3ccc(Br)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C15 compound treatment 0.316 0.063 3.39 3.3872 1.0 1681515 ChemDiv2_003931 Cc1cc(NC(=O)CCc2ccccc2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C16 compound treatment 0.368 0.115 6.18 6.1815 1.0 1101145 ChemDiv2_003932 CCOC(=O)CSc1nnc(o1)c2cc(OC)c(OC)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C17 compound treatment 0.421 0.168 9.03 9.0296 1.0 1335202 ChemDiv2_003933 CC(C)c1ccc(C)cc1OCC(=O)OCCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C18 compound treatment 0.288 0.035 1.88 1.8825 1.0 1218864 ChemDiv2_003934 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3cccs3)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C19 compound treatment 0.327 0.074 3.98 3.9783 1.0 1478851 ChemDiv2_003935 O=C(c1cccc(c1)C(=O)n2cnc3ccccc23)n4cnc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C20 compound treatment 0.256 0.00303 0.16 0.1629 1.0 1624361 ChemDiv2_003936 CCc1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4n3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C21 compound treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1374492 ChemDiv2_003937 Cc1cccc2c(C)nc(Nc3nc(=O)c4ccccc4n3C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C22 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1936152 ChemDiv2_003938 CCOC(=O)/C(=N/O)/C1=NC(C)(C)Cc2cc(OC)c(OC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C23 mock treatment 0.257 0.00403 0.22 0.2166 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 C24 mock treatment 0.261 0.00803 0.43 0.4316 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D01 compound treatment 0.474 0.221 11.88 11.8778 1.0 1985540 ChemDiv2_003939 CC(C)Nc1nc(NC(C)C)nc(OCCOC(=O)Nc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D02 compound treatment 0.285 0.032 1.72 1.7213 1.0 1985541 ChemDiv2_003940 COC(=O)C(CC(C)C)NC(=O)C1c2ccccc2Oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D03 compound treatment 0.245 -0.00797 -0.43 -0.4282 -1.0 1556856 ChemDiv2_003941 CC1(CC2C(C(=O)N3CCOCC3)C(=O)N1CC=C)Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D04 compound treatment 0.516 0.263 14.13 14.1347 1.0 1163961 ChemDiv2_003942 Cc1cc(=O)[nH]c2[nH]nc(c3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D05 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1460437 ChemDiv2_003943 COc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D06 compound treatment 0.341 0.088 4.73 4.7306 1.0 1199261 ChemDiv2_003944 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3ccc(OCC(=O)N)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D07 compound treatment 0.381 0.128 6.88 6.8801 1.0 1471249 ChemDiv2_003945 COc1ccc(OC)c(c1)N2C(=O)CC(Sc3nc4ccccc4s3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D08 compound treatment 0.257 0.00403 0.22 0.2166 1.0 1985542 ChemDiv2_003946 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4nncs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D09 compound treatment 0.266 0.013 0.7 0.7003 1.0 1359643 ChemDiv2_003947 COc1ccc(CCNc2nnc(c3ccccc3)c(=O)n2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D10 compound treatment 0.253 3.12E-5 0.0 0.0017 1.0 1985543 ChemDiv2_003948 CCOc1cc(cc(Br)c1OCC)C2C(=CNC=C2C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D11 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1625431 ChemDiv2_003949 CCOc1nc(nc2ccccc12)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D12 compound treatment 0.431 0.178 9.57 9.567 1.0 1276008 ChemDiv2_003950 O=c1oc(nc2sc3CCCCc3c12)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D13 compound treatment 0.409 0.156 8.38 8.3848 1.0 1924112 ChemDiv2_003951 Cc1ccc(cc1)c2noc(CCc3ccccc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D14 compound treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1331248 ChemDiv2_003952 CN(Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D15 compound treatment 0.259 0.00603 0.32 0.3241 1.0 1617188 ChemDiv2_003953 Cc1cc(=O)n([nH]1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D16 compound treatment 0.428 0.175 9.41 9.4058 1.0 1985544 ChemDiv2_003954 CC1=CC(C)(C)N(C(=O)CSc2nccn2C)c3cc(C)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D17 compound treatment 0.456 0.203 10.91 10.9105 1.0 1234210 ChemDiv2_003955 OCCN1CCN(Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D18 compound treatment 0.387 0.134 7.2 7.2026 1.0 1694731 ChemDiv2_003956 CCOc1nc(OCC)nc(n1)N2CCC(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D19 compound treatment 0.282 0.029 1.56 1.5601 1.0 1717287 ChemDiv2_003957 Cc1cccc(N(CC(=O)Nc2cccnc2)S(=O)(=O)C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D20 compound treatment 0.438 0.185 9.94 9.9432 1.0 1985545 ChemDiv2_003958 CCOc1ccc2sc(NC(=O)CN3C(=O)C4C5CC(C=C5)C4C3=O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D21 compound treatment 0.542 0.289 15.53 15.5319 1.0 1494460 ChemDiv2_003959 O=C(Nc1ccc(cc1)c2nc3ccccc3[nH]2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D22 compound treatment 0.323 0.07 3.76 3.7633 1.0 1985546 ChemDiv2_003960 Nc1ccccc1c2nnc(SCC=C)nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D23 mock treatment 0.252 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 D24 mock treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E01 compound treatment 0.237 -0.016 -0.86 -0.8581 -1.0 1606935 ChemDiv2_003961 CC1CN(CC(C)O1)C(=O)c2cc(nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E02 compound treatment 0.277 0.024 1.29 1.2914 1.0 1938346 ChemDiv2_003962 CCOC(=O)c1c(C)nc2sccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E03 compound treatment 0.264 0.011 0.59 0.5928 1.0 1485500 ChemDiv2_003963 Oc1ccc2c(=O)c(coc2c1CN(CC=C)CC=C)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E04 compound treatment 0.27 0.017 0.92 0.9152 1.0 1152641 ChemDiv2_003964 CC(=C)Cn1c(SCC(=O)N)nc2-c3ccccc3CC4(CCCC4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E05 compound treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1985547 ChemDiv2_003965 CCc1nnc(SCC(=O)OC)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E06 compound treatment 0.29 0.037 1.99 1.99 1.0 1719946 ChemDiv2_003966 CN(Cc1ccccc1)c2nc3n(C)c(=O)[nH]c(=O)c3n2Cc4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E07 compound treatment 0.42 0.167 8.98 8.9759 1.0 1053054 ChemDiv2_003967 O=c1cc(oc2ccccc12)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E08 compound treatment 0.384 0.131 7.04 7.0413 1.0 1553742 ChemDiv2_003968 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E09 compound treatment 0.304 0.051 2.74 2.7423 1.0 1310466 ChemDiv2_003969 Brc1ccccc1C(=O)NCC2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E10 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1243246 ChemDiv2_003970 CC1(C)Cc2ccccc2C(=N1)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E11 compound treatment 0.262 0.00903 0.49 0.4853 1.0 1549340 ChemDiv2_003971 Cc1ccnc(c1)n2c(nc3ccccc3c2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E12 compound treatment 0.355 0.102 5.48 5.4829 1.0 1355628 ChemDiv2_003972 CCOc1ccc(cc1)c2cc(C(=O)OC)c3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E13 compound treatment 0.375 0.122 6.56 6.5577 1.0 1737515 ChemDiv2_003973 COc1cccc(c1)C(=O)N2CCN(CC2)C(=O)c3cc(OC)cc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E14 compound treatment 0.318 0.065 3.49 3.4946 1.0 1372546 ChemDiv2_003974 CCCCN(CC)c1ncnc2ccc(Br)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E15 compound treatment 0.271 0.018 0.97 0.969 1.0 1321399 ChemDiv2_003975 CC(Oc1ccccc1)C(=O)Nc2cc(C)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E16 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1985548 ChemDiv2_003976 Cc1cc(NCCO)nc(n1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E17 compound treatment 0.514 0.261 14.03 14.0273 1.0 1288449 ChemDiv2_003977 Brc1cccc(OCC(=O)OCCN2C(=O)c3ccccc3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E18 compound treatment 0.321 0.068 3.66 3.6559 1.0 1670896 ChemDiv2_003978 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCN3CCNCC3)C2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E19 compound treatment 0.308 0.055 2.96 2.9573 1.0 1300061 ChemDiv2_003979 CN(C)c1ncnc2c3ccccc3[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E20 compound treatment 0.345 0.092 4.95 4.9456 1.0 1147545 ChemDiv2_003980 COC(=O)c1c(C)oc2ccc(OCC(=O)N)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E21 compound treatment 0.306 0.053 2.85 2.8498 1.0 1370594 ChemDiv2_003981 CC(C)n1c(SCc2ccc(F)cc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E22 compound treatment 0.287 0.034 1.83 1.8288 1.0 1985549 ChemDiv2_003982 COc1cc2CC(C)(C)N=C(/C(=N\O)/C#N)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E23 mock treatment 0.26 0.00703 0.38 0.3778 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 E24 mock treatment 0.249 -0.00397 -0.21 -0.2133 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F01 compound treatment 0.244 -0.00897 -0.48 -0.482 -1.0 1578373 ChemDiv2_003983 CN(C)c1nc(SCCO)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F02 compound treatment 0.296 0.043 2.31 2.3124 1.0 1183244 ChemDiv2_003984 COCC(=O)Nc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F03 compound treatment 0.365 0.112 6.02 6.0203 1.0 1531823 ChemDiv2_003985 CN(C)C(=O)c1cc2cccc(CC=C)c2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F04 compound treatment 0.287 0.034 1.83 1.8288 1.0 1690768 ChemDiv2_003986 Cc1nn(c2ccccc2)c3[nH]c(=O)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F05 compound treatment 0.311 0.058 3.12 3.1185 1.0 1572670 ChemDiv2_003987 O=c1n(Cc2ccccc2)n(Cc3ccccc3)c(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F06 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1787081 ChemDiv2_003988 O=C1OC(NCc2cccnc2)(c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F07 compound treatment 0.47 0.217 11.66 11.6628 1.0 1985550 ChemDiv2_003989 CC1=CC(C)(C)N(C(=O)CSc2nc(C)cc(C)n2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F08 compound treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1985551 ChemDiv2_003990 OCc1ccccc1NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F09 compound treatment 0.473 0.22 11.82 11.824 1.0 1985552 ChemDiv2_003991 CCOC(=O)c1sc2ncn(CC(=O)OCC(C)C)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F10 compound treatment 0.264 0.011 0.59 0.5928 1.0 1985553 ChemDiv2_003992 COC(=O)c1scc(C)c1NC(=O)C(C)Sc2nc(C)cc(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F11 compound treatment 0.256 0.00303 0.16 0.1629 1.0 1023746 ChemDiv2_003993 NCCc1c[nH]c2ccc(F)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F12 compound treatment 0.368 0.115 6.18 6.1815 1.0 1985554 ChemDiv2_003994 CCSc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F13 compound treatment 0.293 0.04 2.15 2.1512 1.0 1308916 ChemDiv2_003995 COc1cccc(OCC(=O)N2CCN(C)CC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F14 compound treatment 0.329 0.076 4.09 4.0858 1.0 1930247 ChemDiv2_003996 Cc1nc2n(ncc2c(=O)n1CC=C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F15 compound treatment 0.295 0.042 2.26 2.2587 1.0 1559847 ChemDiv2_003997 COc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F16 compound treatment 0.38 0.127 6.83 6.8264 1.0 1871050 ChemDiv2_003998 COc1cccc(c1)C2C3=C(Nc4c2c(=O)n(C)c(=O)n4C)c5ccccc5C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F17 compound treatment 0.286 0.033 1.78 1.775 1.0 1145453 ChemDiv2_003999 COC(=O)c1ccc(cc1)C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F18 compound treatment 0.247 -0.00597 -0.32 -0.3207 -1.0 1985555 ChemDiv2_004000 CCOC(=O)CN1C(=O)C2CC=C(Cl)CC2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F19 compound treatment 0.339 0.086 4.62 4.6231 1.0 1985556 ChemDiv2_004001 COc1ccccc1N(CC(=O)Nc2ccc(Oc3ccccc3)cc2)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F20 compound treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1985557 ChemDiv2_004002 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)Nc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F21 compound treatment 0.43 0.177 9.51 9.5133 1.0 1985558 ChemDiv2_004003 O=C(Nc1cccc(c1)c2nc3ccccc3s2)c4nc[nH]n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F22 compound treatment 0.25 -0.00297 -0.16 -0.1595 -1.0 1454699 ChemDiv2_004004 Cc1ccc2ccc(C(Nc3ccccn3)c4ccc5OCOc5c4)c(O)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F23 mock treatment 0.247 -0.00597 -0.32 -0.3207 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 F24 mock treatment 0.239 -0.014 -0.75 -0.7507 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G01 compound treatment 0.244 -0.00897 -0.48 -0.482 -1.0 1688675 ChemDiv2_004005 CC(Nc1nc(c2ccccc2)c3cc(C)ccc3n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G02 compound treatment 0.236 -0.017 -0.91 -0.9119 -1.0 1985559 ChemDiv2_004006 Nc1nc(N)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G03 compound treatment 0.559 0.306 16.45 16.4455 1.0 1342611 ChemDiv2_004007 CCCOC(=O)c1ccc(cc1)N2COc3ccc4c(C)cc(=O)oc4c3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G04 compound treatment 0.402 0.149 8.01 8.0086 1.0 1985560 ChemDiv2_004008 CCN(CC)c1ncnc2sc3CC(CCc3c12)(C#N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G05 compound treatment 0.233 -0.02 -1.07 -1.0731 -1.0 1985561 ChemDiv2_004009 CCc1nnc(SCC(=O)N)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G06 compound treatment 0.288 0.035 1.88 1.8825 1.0 1179519 ChemDiv2_004010 Cn1c(=O)n(C)c2nc(N3CCCCC3)n(CCCc4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G07 compound treatment 0.448 0.195 10.48 10.4806 1.0 1415482 ChemDiv2_004011 Oc1ccc2oc(cc(=O)c2c1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G08 compound treatment 0.239 -0.014 -0.75 -0.7507 -1.0 1788140 ChemDiv2_004012 Cc1n[nH]c(=O)nc1NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G09 compound treatment 0.371 0.118 6.34 6.3428 1.0 1492417 ChemDiv2_004013 OCCN1CCN(CC1)C(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G10 compound treatment 0.433 0.18 9.67 9.6745 1.0 1985562 ChemDiv2_004014 Cc1ccc2nc([nH]c2c1)c3cc4ccccc4oc3=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G11 compound treatment 0.393 0.14 7.52 7.525 1.0 1610332 ChemDiv2_004015 CCC1CC(C)(OC1=O)c2csc(Nc3ccccc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G12 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1474699 ChemDiv2_004016 Cc1ccc2nc(C)cc(N3CCOCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G13 compound treatment 0.263 0.01 0.54 0.5391 1.0 1499074 ChemDiv2_004017 CS(=O)(=O)N1CCN(CCCc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G14 compound treatment 0.443 0.19 10.21 10.2119 1.0 1421194 ChemDiv2_004018 OC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G15 compound treatment 0.368 0.115 6.18 6.1815 1.0 1381460 ChemDiv2_004019 CCOC(=O)Cc1csc(NC(=O)CN2C(=O)c3ccccc3C2=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G16 compound treatment 0.267 0.014 0.75 0.754 1.0 1344892 ChemDiv2_004020 Cc1nnc2n(C3CCCCC3)c(=O)c4c5CCCc5sc4n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G17 compound treatment 0.538 0.285 15.32 15.317 1.0 1231822 ChemDiv2_004021 Nc1c(C#N)c2nc3ccccc3nc2n1C4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G18 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1450839 ChemDiv2_004022 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G19 compound treatment 0.404 0.151 8.12 8.1161 1.0 1695689 ChemDiv2_004023 CCN(CC)c1ncnc2c3ccccc3[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G20 compound treatment 0.408 0.155 8.33 8.3311 1.0 1470992 ChemDiv2_004024 COC(=O)C(C)Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G21 compound treatment 0.259 0.00603 0.32 0.3241 1.0 1985563 ChemDiv2_004025 OC(=O)C1C2OC3(CN(C(=O)C13)c4ccccc4)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G22 compound treatment 0.263 0.01 0.54 0.5391 1.0 1648286 ChemDiv2_004026 O=C(Oc1cccc2cccnc12)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G23 mock treatment 0.256 0.00303 0.16 0.1629 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 G24 mock treatment 0.242 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H01 compound treatment 0.266 0.013 0.7 0.7003 1.0 1363433 ChemDiv2_004027 CCOC(=O)Nc1sc(NS(=O)(=O)c2ccc(C)cc2)nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H02 compound treatment 0.245 -0.00797 -0.43 -0.4282 -1.0 1297191 ChemDiv2_004028 CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2c(C)onc2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H03 compound treatment 0.593 0.34 18.27 18.2726 1.0 1128100 ChemDiv2_004029 O=C(Nc1cccc(c1)c2nc3ncccc3o2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H04 compound treatment 0.249 -0.00397 -0.21 -0.2133 -1.0 1641552 ChemDiv2_004030 OC(=O)C(Cc1ccccc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H05 compound treatment 0.402 0.149 8.01 8.0086 1.0 1343091 ChemDiv2_004031 CC(C(=O)c1ccccc1)C2(O)C(=O)N(CCc3ccccc3)c4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H06 compound treatment 0.242 -0.011 -0.59 -0.5894 -1.0 1985564 ChemDiv2_004032 CCOC(=O)C(C1CCCCC1)C(=O)N2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H07 compound treatment 0.363 0.11 5.91 5.9128 1.0 1083393 ChemDiv2_004033 CSc1nsc(SC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H08 compound treatment 0.408 0.155 8.33 8.3311 1.0 1985565 ChemDiv2_004034 O=C(Nc1nncs1)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H09 compound treatment 0.462 0.209 11.23 11.2329 1.0 1985566 ChemDiv2_004035 CCOC(=O)CSc1nnc(o1)c2ccc(cc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H10 compound treatment 0.28 0.027 1.45 1.4526 1.0 1985567 ChemDiv2_004036 CC(=O)Oc1ccc(cc1)C(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H11 compound treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1394912 ChemDiv2_004037 O=C(C1CCCNC1=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H12 compound treatment 0.346 0.093 5.0 4.9993 1.0 1985568 ChemDiv2_004038 C=CCSc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H13 compound treatment 0.467 0.214 11.5 11.5016 1.0 1516589 ChemDiv2_004039 COc1ccccc1C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H14 compound treatment 0.38 0.127 6.83 6.8264 1.0 1938255 ChemDiv2_004040 O=c1oc(nc2sc3CCCCc3c12)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H15 compound treatment 0.551 0.298 16.02 16.0156 1.0 1339554 ChemDiv2_004041 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc4C(=O)NC(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H16 compound treatment 0.419 0.166 8.92 8.9222 1.0 1985569 ChemDiv2_004042 Cc1ccc(cc1)c2nc(no2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H17 compound treatment 0.447 0.194 10.43 10.4268 1.0 1222479 ChemDiv2_004043 CCOc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H18 compound treatment 0.441 0.188 10.1 10.1044 1.0 1502222 ChemDiv2_004044 COc1cc(cc(OC)c1OC)c2nnc(SC(=O)OCc3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H19 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1985570 ChemDiv2_004045 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(CC#N)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H20 compound treatment 0.296 0.043 2.31 2.3124 1.0 1985571 ChemDiv2_004046 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)Nc4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H21 compound treatment 0.465 0.212 11.39 11.3941 1.0 1240358 ChemDiv2_004047 CCc1ccc(Oc2coc3cc(OC(=O)OC)ccc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H22 compound treatment 0.265 0.012 0.65 0.6465 1.0 1393349 ChemDiv2_004048 C(Sc1nnc-2c(OC(Nc3ccccc32)c4ccncc4)n1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H23 mock treatment 0.253 3.12E-5 0.0 0.0017 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 H24 mock treatment 0.243 -0.00997 -0.54 -0.5357 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I01 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1264064 ChemDiv2_004049 O=C(NCc1ccccc1)C2CN(C(=O)C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I02 compound treatment 0.242 -0.011 -0.59 -0.5894 -1.0 1985572 ChemDiv2_004050 CC(=O)Nc1nc(N)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I03 compound treatment 0.356 0.103 5.54 5.5367 1.0 1630449 ChemDiv2_004051 COC(=O)c1cccc(c1)N2COc3ccc4c5CCCc5c(=O)oc4c3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I04 compound treatment 0.297 0.044 2.37 2.3661 1.0 1333763 ChemDiv2_004052 CCN(CC)c1nc(nc2ccccc12)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I05 compound treatment 0.306 0.053 2.85 2.8498 1.0 1935272 ChemDiv2_004053 CCOc1cccc(=O)c2c(C)oc(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I06 compound treatment 0.237 -0.016 -0.86 -0.8581 -1.0 1474130 ChemDiv2_004054 CCn1c(NC)nc2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I07 compound treatment 0.304 0.051 2.74 2.7423 1.0 1172205 ChemDiv2_004055 O=C(Nc1ncnc2sc3CCCc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I08 compound treatment 0.297 0.044 2.37 2.3661 1.0 1985573 ChemDiv2_004056 CCCCN(CC)c1ncnc2ccc(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I09 compound treatment 0.349 0.096 5.16 5.1605 1.0 1985574 ChemDiv2_004057 N#CC1(CCc2c(C1)sc3ncnc(N4CCCC4)c23)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I10 compound treatment 0.26 0.00703 0.38 0.3778 1.0 1577289 ChemDiv2_004058 CC(C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I11 compound treatment 0.266 0.013 0.7 0.7003 1.0 1248301 ChemDiv2_004059 CCCSc1nc2ccccc2c(=O)n1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I12 compound treatment 0.25 -0.00297 -0.16 -0.1595 -1.0 1985575 ChemDiv2_004060 Cc1ccc2nc(C)cc(NCC=C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I13 compound treatment 0.304 0.051 2.74 2.7423 1.0 1315107 ChemDiv2_004061 CCc1ccc(CN2CCN(CC2)C(=O)Cc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I14 compound treatment 0.315 0.062 3.33 3.3334 1.0 1581829 ChemDiv2_004062 O=C(NCCN1CCOCC1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I15 compound treatment 0.298 0.045 2.42 2.4199 1.0 1637910 ChemDiv2_004063 OC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I16 compound treatment 0.444 0.191 10.27 10.2656 1.0 1281521 ChemDiv2_004064 Clc1ccc2nc(oc(=O)c2c1)c3ccc4C(=O)N(CC5CCCO5)C(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I17 compound treatment 0.594 0.341 18.33 18.3263 1.0 1985576 ChemDiv2_004065 O=C(COC(=O)c1cccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I18 compound treatment 0.288 0.035 1.88 1.8825 1.0 1563751 ChemDiv2_004066 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I19 compound treatment 0.26 0.00703 0.38 0.3778 1.0 1679216 ChemDiv2_004067 CCOCc1cnc(C)nc1NCC(=O)c2c(C)n(C)c3ccc(OC)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I20 compound treatment 0.523 0.27 14.51 14.5109 1.0 1315726 ChemDiv2_004068 COc1ccc(CCNc2nnc(c3ccccc3)c(=O)[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I21 compound treatment 0.428 0.175 9.41 9.4058 1.0 1560002 ChemDiv2_004069 O=C(CC1SC(=O)NC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I22 compound treatment 0.269 0.016 0.86 0.8615 1.0 1247513 ChemDiv2_004070 CCCCS(=O)c1sc2nc(C)cc(C)c2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I23 mock treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 I24 mock treatment 0.262 0.00903 0.49 0.4853 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J01 compound treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1636508 ChemDiv2_004071 O=c1[nH]c2ccccc2nc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J02 compound treatment 0.298 0.045 2.42 2.4199 1.0 1574560 ChemDiv2_004072 Fc1ccc(NC(=O)C2CCC(CC2)N3C(=O)C4C5CC(C=C5)C4C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J03 compound treatment 0.596 0.343 18.43 18.4338 1.0 1603978 ChemDiv2_004073 O=C(COc1ccccc1)Nc2cccc(c2)c3nc4ncccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J04 compound treatment 0.364 0.111 5.97 5.9666 1.0 1985577 ChemDiv2_004074 CC1(C)Cc2c(C#N)c(sc2CO1)N3C(=O)C4CC=C(Cl)CC4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J05 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1385447 ChemDiv2_004075 CCOC(=O)C1C2C(C)C(C)(NC1=O)Oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J06 compound treatment 0.262 0.00903 0.49 0.4853 1.0 1985578 ChemDiv2_004076 CCOC(=O)C(Cc1ccccc1)C(=O)N2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J07 compound treatment 0.343 0.09 4.84 4.8381 1.0 1985579 ChemDiv2_004077 CCCOC(=O)CN1C(=O)c2ccc(Br)cc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J08 compound treatment 0.318 0.065 3.49 3.4946 1.0 1258167 ChemDiv2_004078 OC(=O)c1cc(C(=O)O)c2cc(Cl)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J09 compound treatment 0.263 0.01 0.54 0.5391 1.0 1788728 ChemDiv2_004079 NCCOC(=O)Nc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J10 compound treatment 0.253 3.12E-5 0.0 0.0017 1.0 1583260 ChemDiv2_004080 CC(Sc1nc2ccccc2n1Cc3ccccc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J11 compound treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1559143 ChemDiv2_004081 CC(C)NCC(O)COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J12 compound treatment 0.304 0.051 2.74 2.7423 1.0 1985580 ChemDiv2_004082 CC1CCc2c(C1)sc3ncnc(SCC=C)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J13 compound treatment 0.4 0.147 7.9 7.9012 1.0 1245318 ChemDiv2_004083 CCOC(=O)c1c(CSC#N)oc2ccc(OC(=O)C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J14 compound treatment 0.464 0.211 11.34 11.3404 1.0 1460387 ChemDiv2_004084 CCOC(=O)c1cnc2c(ccc3ccccc32)c1NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J15 compound treatment 0.452 0.199 10.7 10.6955 1.0 1371985 ChemDiv2_004085 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc-4c(COc5ccccc45)s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J16 compound treatment 0.372 0.119 6.4 6.3965 1.0 1121878 ChemDiv2_004086 COC(=O)c1cn(C(=O)c2cccs2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J17 compound treatment 0.262 0.00903 0.49 0.4853 1.0 1599498 ChemDiv2_004087 CC(O)CSc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(=C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J18 compound treatment 0.32 0.067 3.6 3.6021 1.0 1985581 ChemDiv2_004088 OC(=O)CCC(=O)Nc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J19 compound treatment 0.358 0.105 5.64 5.6442 1.0 1985582 ChemDiv2_004089 Clc1ccc(NC(=O)OCN2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J20 compound treatment 0.274 0.021 1.13 1.1302 1.0 1985583 ChemDiv2_004090 CCCc1nnc(NC(=O)C(C)N2C(=O)C3C4CC(C=C4)C3C2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J21 compound treatment 0.324 0.071 3.82 3.8171 1.0 1738660 ChemDiv2_004091 CC(=O)Oc1cccc(Nc2ncnc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J22 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1439414 ChemDiv2_004092 Cc1cccc(NC(c2cccc(OCC=C)c2)c3ccc4cccnc4c3O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J23 mock treatment 0.243 -0.00997 -0.54 -0.5357 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 J24 mock treatment 0.257 0.00403 0.22 0.2166 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K01 compound treatment 0.349 0.096 5.16 5.1605 1.0 1787231 ChemDiv2_004093 CCn1c(NCc2ccccc2O)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K02 compound treatment 0.366 0.113 6.07 6.0741 1.0 1944426 ChemDiv2_004094 CSc1nnc(c2ccccc2)c(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K03 compound treatment 0.256 0.00303 0.16 0.1629 1.0 1985584 ChemDiv2_004095 Cc1nnc2c3c(csc3ncn12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K04 compound treatment 0.321 0.068 3.66 3.6559 1.0 1985585 ChemDiv2_004096 CCCOc1ccc(cc1)c2nc(NCCN)c3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K05 compound treatment 0.238 -0.015 -0.8 -0.8044 -1.0 1181297 ChemDiv2_004097 CCOc1cc(cc(=O)c2c(C)oc(C)c12)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K06 compound treatment 0.294 0.041 2.2 2.2049 1.0 1337936 ChemDiv2_004098 Cn1c(=O)n(C)c2nc(NCC=C)n(Cc3ccc(F)cc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K07 compound treatment 0.511 0.258 13.87 13.8661 1.0 1985586 ChemDiv2_004099 Brc1cnc2[nH]c(SCc3ccccc3C#N)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K08 compound treatment 0.249 -0.00397 -0.21 -0.2133 -1.0 1364518 ChemDiv2_004100 CC1(C)Cc2c(CO1)sc3nc([nH]c(=O)c23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K09 compound treatment 0.26 0.00703 0.38 0.3778 1.0 1625468 ChemDiv2_004101 COc1cc(cc(OC)c1OC)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K10 compound treatment 0.309 0.056 3.01 3.011 1.0 1200092 ChemDiv2_004102 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K11 compound treatment 0.257 0.00403 0.22 0.2166 1.0 1311236 ChemDiv2_004103 CSc1nc2ccccc2c(=O)n1CC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K12 compound treatment 0.264 0.011 0.59 0.5928 1.0 1677229 ChemDiv2_004104 CCCCN(C)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K13 compound treatment 0.248 -0.00497 -0.27 -0.267 -1.0 1285445 ChemDiv2_004105 CC(C)N1CCN(CC1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K14 compound treatment 0.258 0.00503 0.27 0.2704 1.0 1140828 ChemDiv2_004106 O=C1CC(c2ccccc2)n3ncnc3N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K15 compound treatment 0.265 0.012 0.65 0.6465 1.0 1523696 ChemDiv2_004107 CCCn1c(NC(=O)C2CCCCC2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K16 compound treatment 0.399 0.146 7.85 7.8474 1.0 1720633 ChemDiv2_004108 CCCOc1cccc(c1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K17 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1985587 ChemDiv2_004109 Cc1ccc(cc1)S(=O)(=O)CCc2nc3ccccc3n2CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K18 compound treatment 0.275 0.022 1.18 1.1839 1.0 1985588 ChemDiv2_004110 CCN(CC)CCSc1nc2ccccc2c(=O)n1c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K19 compound treatment 0.264 0.011 0.59 0.5928 1.0 1422263 ChemDiv2_004111 Cc1[nH]c2cc(C)ccc2c1C(=O)CNc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K20 compound treatment 0.264 0.011 0.59 0.5928 1.0 1507069 ChemDiv2_004112 Cc1n[nH]c(=O)nc1NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K21 compound treatment 0.334 0.081 4.35 4.3544 1.0 1295730 ChemDiv2_004113 Oc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K22 compound treatment 0.359 0.106 5.7 5.6979 1.0 1414391 ChemDiv2_004114 CCCCS(=O)c1sc2nc3CCCCc3cc2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K23 mock treatment 0.265 0.012 0.65 0.6465 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 K24 mock treatment 0.266 0.013 0.7 0.7003 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L01 compound treatment 0.343 0.09 4.84 4.8381 1.0 1585607 ChemDiv2_004115 CC(=O)n1c2C(=O)CCCc2c3cc(C)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L02 compound treatment 0.38 0.127 6.83 6.8264 1.0 1985589 ChemDiv2_004116 COC(=O)c1ccc(C)c(NC(=O)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L03 compound treatment 0.484 0.231 12.42 12.4151 1.0 1647651 ChemDiv2_004117 CC(C)CC(=O)Nc1cc(ccc1C)c2nc3ncccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L04 compound treatment 0.266 0.013 0.7 0.7003 1.0 1985590 ChemDiv2_004118 OC(=O)C1CC=C(Cl)CC1C(=O)NCC2OCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L05 compound treatment 0.34 0.087 4.68 4.6769 1.0 1507006 ChemDiv2_004119 CSc1nc(SC)c2c3CCN(C)Cc3sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L06 compound treatment 0.276 0.023 1.24 1.2377 1.0 1781197 ChemDiv2_004120 O=C1C2ON(C(C2C(=O)N1Cc3ccccc3)c4ccco4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L07 compound treatment 0.279 0.026 1.4 1.3989 1.0 1332115 ChemDiv2_004121 CC(C)(C)C1CCc2c(C(=O)N3CCCC3)c(NC(=O)c4ccco4)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L08 compound treatment 0.238 -0.015 -0.8 -0.8044 -1.0 1985591 ChemDiv2_004122 Fc1cccc2C3C=CCC3C(Nc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L09 compound treatment 0.3 0.047 2.53 2.5274 1.0 1985592 ChemDiv2_004123 CCCCc1nnc(SCC(=O)Nc2ncccn2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L10 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1469291 ChemDiv2_004124 OC(=O)Cn1c(SC2CCCCC2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L11 compound treatment 0.242 -0.011 -0.59 -0.5894 -1.0 1316454 ChemDiv2_004125 COc1ccc2c(CCN)c[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L12 compound treatment 0.262 0.00903 0.49 0.4853 1.0 1213639 ChemDiv2_004126 OCCN1CCN(CC1)c2ncnc3ccc(Br)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L13 compound treatment 0.278 0.025 1.35 1.3451 1.0 1257376 ChemDiv2_004127 CNc1nc2n(C)c(=O)n(C)c(=O)c2n1CC(O)COc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L14 compound treatment 0.319 0.066 3.55 3.5484 1.0 1360890 ChemDiv2_004128 CCOC(=O)c1cnc2c(C)c(Cl)ccc2c1N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L15 compound treatment 0.558 0.305 16.39 16.3917 1.0 1985593 ChemDiv2_004129 Cc1cc(C)nc(SCc2n[nH]c(=S)o2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L16 compound treatment 0.264 0.011 0.59 0.5928 1.0 1985594 ChemDiv2_004130 Clc1ccc(CC(=O)Nc2nc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L17 compound treatment 0.41 0.157 8.44 8.4385 1.0 1665366 ChemDiv2_004131 Cc1cccc(Cn2c(SCC=C)nc3n(C)c(=O)n(C)c(=O)c23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L18 compound treatment 0.435 0.182 9.78 9.782 1.0 1985595 ChemDiv2_004132 CCCC(=O)Nc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L19 compound treatment 0.263 0.01 0.54 0.5391 1.0 1656195 ChemDiv2_004133 CC(C)Nc1nc(NC(C)C)nc(OCC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L20 compound treatment 0.259 0.00603 0.32 0.3241 1.0 1985596 ChemDiv2_004134 OC(Cn1c(=N)n(CC=C)c2ccccc12)c3cccc(Br)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L21 compound treatment 0.434 0.181 9.73 9.7282 1.0 1329450 ChemDiv2_004135 COc1cc(cc(OC)c1OC)C(=O)Oc2cccc(Nc3ncnc4ccccc34)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L22 compound treatment 0.365 0.112 6.02 6.0203 1.0 1426441 ChemDiv2_004136 COC(=O)c1ccc(cc1)C(Nc2ccccn2)c3ccc4ccc(C)nc4c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L23 mock treatment 0.241 -0.012 -0.64 -0.6432 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 L24 mock treatment 0.254 0.00103 0.06 0.0554 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M01 compound treatment 0.394 0.141 7.58 7.5787 1.0 1787236 ChemDiv2_004137 Cn1c(NCc2cc(Cl)ccc2O)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M02 compound treatment 0.289 0.036 1.94 1.9362 1.0 1985597 ChemDiv2_004138 CC(=C)Cn1c(SCC=C)nc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M03 compound treatment 0.244 -0.00897 -0.48 -0.482 -1.0 1246133 ChemDiv2_004139 CCC(CO)Nc1nc(C)nc2sc3CCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M04 compound treatment 0.291 0.038 2.04 2.0437 1.0 1985598 ChemDiv2_004140 COC(=O)CNc1nc(nc2ccccc12)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M05 compound treatment 0.454 0.201 10.8 10.803 1.0 1659336 ChemDiv2_004141 CCOc1cc(cc(=O)c2c(C)oc(C)c12)c3ccc(O)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M06 compound treatment 0.263 0.01 0.54 0.5391 1.0 1521556 ChemDiv2_004142 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M07 compound treatment 0.243 -0.00997 -0.54 -0.5357 -1.0 1852545 ChemDiv2_004143 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(F)cc3)C(=O)Nc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M08 compound treatment 0.259 0.00603 0.32 0.3241 1.0 1711439 ChemDiv2_004144 Cn1c(NCc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M09 compound treatment 0.279 0.026 1.4 1.3989 1.0 1941082 ChemDiv2_004145 Nc1cc(O)nc(SCc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M10 compound treatment 0.438 0.185 9.94 9.9432 1.0 1873332 ChemDiv2_004146 Nc1c(sc2[nH]c(=O)c(cc12)C(=O)O)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M11 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1357607 ChemDiv2_004147 CCSc1nc2ccccc2c(=O)n1CC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M12 compound treatment 0.253 3.12E-5 0.0 0.0017 1.0 1283051 ChemDiv2_004148 CCN1CCN(Cc2c(O)ccc3c(=O)c(coc23)c4ccccc4Cl)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M13 compound treatment 0.272 0.019 1.02 1.0227 1.0 1199270 ChemDiv2_004149 CC(C)CC(=O)N1CCN(CC2CCC=CC2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M14 compound treatment 0.419 0.166 8.92 8.9222 1.0 1985599 ChemDiv2_004150 OCC(O)Cn1c(SCCSc2nc3ccccc3n2CC(O)CO)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M15 compound treatment 0.445 0.192 10.32 10.3194 1.0 1562625 ChemDiv2_004151 NC(=O)COc1ccc(Nc2nnc(c3ccccc3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M16 compound treatment 0.39 0.137 7.36 7.3638 1.0 1274097 ChemDiv2_004152 CC(C)CCN1C(=O)c2ccc(cc2C1=O)c3nc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M17 compound treatment 0.456 0.203 10.91 10.9105 1.0 1488203 ChemDiv2_004153 CC(=O)Nc1nnc(SCC(=O)c2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M18 compound treatment 0.466 0.213 11.45 11.4479 1.0 1209322 ChemDiv2_004154 CN(C)Cc1c(O)ccc2cc(c3nc4ccccc4s3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M19 compound treatment 0.258 0.00503 0.27 0.2704 1.0 1247196 ChemDiv2_004155 COc1ccc2n(C)c(C)c(C(=O)CNc3nccs3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M20 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1434210 ChemDiv2_004156 CN(C)Cc1c(C)nc2ccccc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M21 compound treatment 0.26 0.00703 0.38 0.3778 1.0 1985600 ChemDiv2_004157 CCN(CC)Cc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M22 compound treatment 0.301 0.048 2.58 2.5811 1.0 1602483 ChemDiv2_004158 Nc1c(sc2nc3CCCCc3cc12)S(=O)Cc4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M23 mock treatment 0.266 0.013 0.7 0.7003 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 M24 mock treatment 0.252 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N01 compound treatment 0.26 0.00703 0.38 0.3778 1.0 1407265 ChemDiv2_004159 Cc1ccc2n(CC(O)CNc3ccccc3)c4C(=O)CCCc4c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N02 compound treatment 0.262 0.00903 0.49 0.4853 1.0 1658265 ChemDiv2_004160 OCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N03 compound treatment 0.522 0.269 14.46 14.4572 1.0 1985601 ChemDiv2_004161 COC(=O)c1ccc(NC(=O)CN(Cc2ccccc2)S(=O)(=O)c3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N04 compound treatment 0.263 0.01 0.54 0.5391 1.0 1582646 ChemDiv2_004162 Cc1cc(C)nc(SCc2nc3ccccc3c(=O)n2c4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N05 compound treatment 0.32 0.067 3.6 3.6021 1.0 1985602 ChemDiv2_004163 Cc1cc(NCc2ccccc2)nc(NCc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N06 compound treatment 0.346 0.093 5.0 4.9993 1.0 1592562 ChemDiv2_004164 COc1ccc(cc1O)C2C3C(ON2c4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N07 compound treatment 0.257 0.00403 0.22 0.2166 1.0 1125067 ChemDiv2_004165 Cc1cc(NCc2ccccc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N08 compound treatment 0.443 0.19 10.21 10.2119 1.0 1985603 ChemDiv2_004166 CSc1nnc(c2ccccc2N)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N09 compound treatment 0.453 0.2 10.75 10.7493 1.0 1243491 ChemDiv2_004167 CCCn1c2ccccc2c3nnc(SC(CC)C(=O)Nc4cc(C)on4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N10 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1391940 ChemDiv2_004168 Cc1ccc(Nc2nnc(C)c(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N11 compound treatment 0.422 0.169 9.08 9.0834 1.0 1282668 ChemDiv2_004169 CN(C)c1ccnc2sc3c(=O)n(cnc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N12 compound treatment 0.385 0.132 7.1 7.0951 1.0 1376108 ChemDiv2_004170 CCC(Oc1ccc2c(c1)oc(=O)c3ccccc32)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N13 compound treatment 0.249 -0.00397 -0.21 -0.2133 -1.0 1469143 ChemDiv2_004171 CCCn1c(NC)nc2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N14 compound treatment 0.377 0.124 6.67 6.6652 1.0 1444014 ChemDiv2_004172 COC(=O)Oc1ccc2c(=O)c(Oc3cccc(C)c3)coc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N15 compound treatment 0.531 0.278 14.94 14.9408 1.0 1985604 ChemDiv2_004173 S=c1[nH]nc(CSc2nc3ccccc3s2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N16 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1985605 ChemDiv2_004174 COc1ccc(CC(=O)Nc2nc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N17 compound treatment 0.323 0.07 3.76 3.7633 1.0 1788896 ChemDiv2_004175 CSc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N18 compound treatment 0.551 0.298 16.02 16.0156 1.0 1985606 ChemDiv2_004176 O=C(Nc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N19 compound treatment 0.263 0.01 0.54 0.5391 1.0 1490286 ChemDiv2_004177 CCCCc1nc2sc3c(=O)[nH]cnc3c2c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N20 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1985607 ChemDiv2_004178 Cn1c(=O)n(C)c2cn(C3CCCCC3)c(c4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N21 compound treatment 0.43 0.177 9.51 9.5133 1.0 1123686 ChemDiv2_004179 O=C(Oc1cccc(Nc2ncnc3ccccc23)c1)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N22 compound treatment 0.287 0.034 1.83 1.8288 1.0 1535427 ChemDiv2_004180 C=CCSc1nnc-2c(OC3(CCCC3)Nc4ccccc42)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N23 mock treatment 0.246 -0.00697 -0.37 -0.3745 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 N24 mock treatment 0.252 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O01 compound treatment 0.256 0.00303 0.16 0.1629 1.0 1787241 ChemDiv2_004181 CC(Nc1nc2ccccc2n1C)c3cc(Cl)ccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O02 compound treatment 0.254 0.00103 0.06 0.0554 1.0 1939173 ChemDiv2_004182 CSc1nc(C)cc(n1)n2ccc(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O03 compound treatment 0.55 0.297 15.96 15.9618 1.0 1315048 ChemDiv2_004183 OCCNC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O04 compound treatment 0.253 3.12E-5 0.0 0.0017 1.0 1985608 ChemDiv2_004184 COC(=O)c1ccc(Oc2nc(nc3ccccc23)c4cccnc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O05 compound treatment 0.514 0.261 14.03 14.0273 1.0 1308020 ChemDiv2_004185 COc1ccc(cc1)c2cc(=O)c3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O06 compound treatment 0.258 0.00503 0.27 0.2704 1.0 1405685 ChemDiv2_004186 Cn1c(=O)n(C)c2[nH]c(=N)c(nc2c1=O)c3nnc4CCCCCn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O07 compound treatment 0.268 0.015 0.81 0.8077 1.0 1423988 ChemDiv2_004187 CC1=C(C(C2=C(CCCC2=O)N1)c3cccs3)C(=O)Nc4cccc(F)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O08 compound treatment 0.291 0.038 2.04 2.0437 1.0 1939615 ChemDiv2_004188 CCN(CC)c1nc(C)cc(COC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O09 compound treatment 0.32 0.067 3.6 3.6021 1.0 1228828 ChemDiv2_004189 O=C(Oc1ccc2oc(=O)sc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O10 compound treatment 0.286 0.033 1.78 1.775 1.0 1329682 ChemDiv2_004190 NC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O11 compound treatment 0.308 0.055 2.96 2.9573 1.0 1985609 ChemDiv2_004191 CCn1c(SC)nc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O12 compound treatment 0.26 0.00703 0.38 0.3778 1.0 1593808 ChemDiv2_004192 Brc1ccc2ncnc(N3CCOCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O13 compound treatment 0.258 0.00503 0.27 0.2704 1.0 1281647 ChemDiv2_004193 CCNc1ccccc1c2nc3ccccc3[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O14 compound treatment 0.468 0.215 11.56 11.5553 1.0 1432392 ChemDiv2_004194 CCn1c(SCc2nc3ccccc3[nH]2)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O15 compound treatment 0.413 0.16 8.6 8.5997 1.0 1985610 ChemDiv2_004195 Cc1ccccc1OCCCC(=O)Nc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O16 compound treatment 0.434 0.181 9.73 9.7282 1.0 1985611 ChemDiv2_004196 COc1ccccc1OCC(=O)Nc2ccc(cc2)c3nnc(o3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O17 compound treatment 0.275 0.022 1.18 1.1839 1.0 1933665 ChemDiv2_004197 Cc1cc(O)nc(NCc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O18 compound treatment 0.273 0.02 1.08 1.0764 1.0 1288061 ChemDiv2_004198 CCc1cc2c(=O)c(c3nc4ccccc4[nH]3)c(C)oc2cc1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O19 compound treatment 0.263 0.01 0.54 0.5391 1.0 1985612 ChemDiv2_004199 CSc1nc2sc3COC(Cc3c2c(=O)n1c4ccccc4)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O20 compound treatment 0.29 0.037 1.99 1.99 1.0 1985613 ChemDiv2_004200 C=CCNc1ncnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O21 compound treatment 0.271 0.018 0.97 0.969 1.0 1366272 ChemDiv2_004201 Cc1c(NC(=O)c2ccc3OCCOc3c2)cccc1c4nc5ncccc5o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O22 compound treatment 0.282 0.029 1.56 1.5601 1.0 1529850 ChemDiv2_004202 O=C1CCCCC1Sc2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O23 mock treatment 0.26 0.00703 0.38 0.3778 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 O24 mock treatment 0.266 0.013 0.7 0.7003 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P01 compound treatment 0.249 -0.00397 -0.21 -0.2133 -1.0 1304053 ChemDiv2_004203 CC(C)NCC(O)Cn1c2C(=O)CCCc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P02 compound treatment 0.244 -0.00897 -0.48 -0.482 -1.0 1138265 ChemDiv2_004204 COc1ccccc1C2N(CC(C)O)C(=O)C(=C2C(=O)c3ccccc3)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P03 compound treatment 0.257 0.00403 0.22 0.2166 1.0 1238501 ChemDiv2_004205 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3CN(C(=O)C3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P04 compound treatment 0.293 0.04 2.15 2.1512 1.0 1985614 ChemDiv2_004206 CCOC(=O)N1CCN(CC1)C(=O)CSc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P05 compound treatment 0.261 0.00803 0.43 0.4316 1.0 1932623 ChemDiv2_004207 CC(=O)N1c2ccccc2C(=CC1(C)C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P06 compound treatment 0.299 0.046 2.47 2.4736 1.0 1661966 ChemDiv2_004208 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2)nc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P07 compound treatment 0.329 0.076 4.09 4.0858 1.0 1168548 ChemDiv2_004209 Cc1cc(C)c(NC(=O)C2COc3ccccc3O2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P08 compound treatment 0.318 0.065 3.49 3.4946 1.0 1248403 ChemDiv2_004210 Brc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P09 compound treatment 0.281 0.028 1.51 1.5063 1.0 1137306 ChemDiv2_004211 CCCc1nc(NC(=O)C)c(C#N)c(c1CC)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P10 compound treatment 0.284 0.031 1.67 1.6676 1.0 1985615 ChemDiv2_004212 CCOC(=O)C(C)Sc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P11 compound treatment 0.415 0.162 8.71 8.7072 1.0 1419811 ChemDiv2_004213 COc1cc(ccc1O)C2N(C(=O)c3[nH]nc(c23)c4ccc(F)cc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P12 compound treatment 0.25 -0.00297 -0.16 -0.1595 -1.0 1622871 ChemDiv2_004214 CCCOC(=O)COc1ccc2c(=O)c(coc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P13 compound treatment 0.245 -0.00797 -0.43 -0.4282 -1.0 1182479 ChemDiv2_004215 CCOC(=O)c1c(C)oc2c1c(C(N3CCN(C)CC3)c4ccccn4)c(O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P14 compound treatment 0.333 0.08 4.3 4.3007 1.0 1985616 ChemDiv2_004216 CSc1nnc(c2ccco2)c(n1)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P15 compound treatment 0.25 -0.00297 -0.16 -0.1595 -1.0 1690069 ChemDiv2_004217 CC1=C(C(c2ccccc2)c3c(N1)[nH]c(=O)[nH]c3=O)C(=O)OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P16 compound treatment 0.299 0.046 2.47 2.4736 1.0 1184251 ChemDiv2_004218 O=C(CCc1ccccc1)N2CCN(Cc3ccc4OCOc4c3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P17 compound treatment 0.279 0.026 1.4 1.3989 1.0 1788897 ChemDiv2_004219 COc1ccc(OC)c(c1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P18 compound treatment 0.255 0.00203 0.11 0.1092 1.0 1570805 ChemDiv2_004220 C(CN1CCOCC1)Nc2ncnc3scc(c4ccccc4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P19 compound treatment 0.242 -0.011 -0.59 -0.5894 -1.0 1985617 ChemDiv2_004221 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2C(=O)OC)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P20 compound treatment 0.252 -9.69E-4 -0.05 -0.0521 -1.0 1985618 ChemDiv2_004222 Cc1n(Cc2ccccc2)c(C)c3c(C)nnc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P21 compound treatment 0.245 -0.00797 -0.43 -0.4282 -1.0 1263507 ChemDiv2_004223 Cc1cccc(c1)N2C(=O)C3ON(C(C3C2=O)c4ccco4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P22 compound treatment 0.272 0.019 1.02 1.0227 1.0 1985619 ChemDiv2_004224 CSc1nnc-2c(OC(N(C(=O)c3ccccc3)c4ccccc42)c5ccco5)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P23 mock treatment 0.243 -0.00997 -0.54 -0.5357 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1380 P24 mock treatment 0.251 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A01 compound treatment 0.376 0.142 7.61 7.6056 1.0 1985620 ChemDiv2_004225 Nc1ccccc1c2nnc(SCc3ccccc3)nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A02 compound treatment 0.225 -0.00947 -0.51 -0.5088 -1.0 1259237 ChemDiv2_004226 CCOC(=O)c1cnc2ccc(C)cc2c1NCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A03 compound treatment 0.276 0.0415 2.23 2.2318 1.0 1985621 ChemDiv2_004227 CSc1nc(C)cc(OCCNS(=O)(=O)c2ccc(C)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A04 compound treatment 0.301 0.0665 3.58 3.5753 1.0 1985622 ChemDiv2_004228 COc1ccc(CCNC(=O)CSc2nc(O)cc(=O)[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A05 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1871144 ChemDiv2_004229 O=C1C2=C(Nc3[nH]c(=O)[nH]c(=O)c3C2c4ccccc4)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A06 compound treatment 0.237 0.00253 0.14 0.136 1.0 1571414 ChemDiv2_004230 Cc1ccc(cc1)C2C3=C(CCCC3=O)Nc4c2c(=O)n(C)c(=O)n4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A07 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1563905 ChemDiv2_004231 C(N1CCN(Cc2ccccc2)CC1)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A08 compound treatment 0.42 0.186 9.97 9.9701 1.0 1985623 ChemDiv2_004232 Cc1nnc(Nc2ccc(CC(=O)N)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A09 compound treatment 0.25 0.0155 0.83 0.8346 1.0 1985624 ChemDiv2_004233 CCC(C)Nc1nc(nc2ccccc12)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A10 compound treatment 0.234 -4.69E-4 -0.03 -0.0252 -1.0 1382446 ChemDiv2_004234 COC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A11 compound treatment 0.231 -0.00347 -0.19 -0.1864 -1.0 1985625 ChemDiv2_004235 CC(=O)Oc1ccc2nc(oc(=O)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A12 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1985626 ChemDiv2_004236 OCn1nnc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A13 compound treatment 0.426 0.192 10.29 10.2925 1.0 1699438 ChemDiv2_004237 Cc1sc2nc3c4ccccc4c(NCc5ccco5)nn3c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A14 compound treatment 0.227 -0.00747 -0.4 -0.4014 -1.0 1985627 ChemDiv2_004238 CC(C)(C)OC(=O)C1C(/C=C/c2ccccc2)C(C(=O)OC(C)(C)C)C(C)(O)CC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A15 compound treatment 0.226 -0.00847 -0.46 -0.4551 -1.0 1059825 ChemDiv2_004239 CC1(NCCc2c1[nH]c3ccccc23)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A16 compound treatment 0.323 0.0885 4.76 4.7575 1.0 1985628 ChemDiv2_004240 Oc1nc(O)nc(Nc2nc(=O)c3ccccc3s2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A17 compound treatment 0.241 0.00653 0.35 0.351 1.0 1985629 ChemDiv2_004241 CCOC(=O)c1c(NC(=O)c2c(Br)cnn2C)c(C#N)nn1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A18 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1197817 ChemDiv2_004242 COc1ccc(OC)c(c1)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A19 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1985630 ChemDiv2_004243 CC(C)C(Nc1ncnc2sc3CCCc3c12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A20 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1985631 ChemDiv2_004244 COc1ccc(cc1)N2CCN(CC2)c3nc(NCCc4ccc(OC)c(OC)c4)nc(OC)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A21 compound treatment 0.384 0.15 8.04 8.0355 1.0 1985632 ChemDiv2_004245 CCOC(=O)c1ccc(cc1)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A22 compound treatment 0.276 0.0415 2.23 2.2318 1.0 1985633 ChemDiv2_004246 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccc(cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A23 mock treatment 0.229 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 A24 mock treatment 0.246 0.0115 0.62 0.6197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B01 compound treatment 0.238 0.00353 0.19 0.1898 1.0 1985634 ChemDiv2_004247 Cc1ccc(cc1S(=O)(=O)N)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B02 compound treatment 0.29 0.0555 2.98 2.9841 1.0 1985635 ChemDiv2_004248 COc1ccc(CCNCC(O)Cn2c3C(=O)N(C)CCc3c4ccccc24)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B03 compound treatment 0.503 0.269 14.43 14.4303 1.0 1985636 ChemDiv2_004249 CCc1nnc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C4CC=C(Cl)CC4C3=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B04 compound treatment 0.274 0.0395 2.12 2.1243 1.0 1871770 ChemDiv2_004250 CCN(C(=O)COc1ccccc1)c2nnc(s2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B05 compound treatment 0.345 0.111 5.94 5.9397 1.0 1850728 ChemDiv2_004251 OC(=O)c1ccc(NC(=O)CSc2nnc(c3ccco3)c(n2)c4ccco4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B06 compound treatment 0.255 0.0205 1.1 1.1033 1.0 1985637 ChemDiv2_004252 CCC(Sc1nc(C)cc(C)n1)C(=O)NC(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B07 compound treatment 0.501 0.267 14.32 14.3228 1.0 1985638 ChemDiv2_004253 Cc1ccc(OCC(=O)Nc2cccc(c2)c3nc4ccccc4c(=O)o3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B08 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1985639 ChemDiv2_004254 CCCN1C(=O)c2ccc(cc2C1=O)c3nc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B09 compound treatment 0.279 0.0445 2.39 2.393 1.0 1985640 ChemDiv2_004255 O=C(Cn1c(=O)sc2ccccc12)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B10 compound treatment 0.311 0.0765 4.11 4.1126 1.0 1488526 ChemDiv2_004256 O=C(CNC(=O)c1ccco1)OCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B11 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1985641 ChemDiv2_004257 CC(C)C1Cc2c(CO1)sc3nc(SCC(=O)O)n(c4ccccc4)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B12 compound treatment 0.308 0.0735 3.95 3.9514 1.0 1985642 ChemDiv2_004258 NC(=O)C1CCN(CC1)C(=O)CSc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B13 compound treatment 0.265 0.0305 1.64 1.6407 1.0 1272574 ChemDiv2_004259 Cc1cccc(c1)c2nc(O)c3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B14 compound treatment 0.247 0.0125 0.67 0.6734 1.0 1192614 ChemDiv2_004260 CCN(CC)CCNc1nc(CC)c2COC(C)(C)Cc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B15 compound treatment 0.288 0.0535 2.88 2.8767 1.0 1985643 ChemDiv2_004261 COc1cccc(OC)c1C(=O)Nc2nnc(s2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B16 compound treatment 0.297 0.0625 3.36 3.3603 1.0 1985644 ChemDiv2_004262 COc1ccccc1c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B17 compound treatment 0.254 0.0195 1.05 1.0496 1.0 1985645 ChemDiv2_004263 O=C(N1CCN(CC1)c2ccccc2)c3cc(=O)n4c5ccccc5nc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B18 compound treatment 0.428 0.194 10.4 10.4 1.0 1322124 ChemDiv2_004264 COc1cc(cc(OC)c1OC)C2Nc3ccccc3-c4nc5ccccc5n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B19 compound treatment 0.291 0.0565 3.04 3.0379 1.0 1209891 ChemDiv2_004265 CN(C1CCN(C)CC1)c2ncnc3ccc(Br)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B20 compound treatment 0.225 -0.00947 -0.51 -0.5088 -1.0 1323471 ChemDiv2_004266 CCc1ccccc1Nc2nc(=O)[nH]nc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B21 compound treatment 0.274 0.0395 2.12 2.1243 1.0 1985646 ChemDiv2_004267 O=C(Nc1ccccc1)c2cc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B22 compound treatment 0.248 0.0135 0.73 0.7271 1.0 1985647 ChemDiv2_004268 Cc1cc(C)n(CC(=O)NCc2cc(ccc2C)c3nn(C)c(=O)c4ccccc34)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B23 mock treatment 0.236 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 B24 mock treatment 0.229 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C01 compound treatment 0.233 -0.00147 -0.08 -0.0789 -1.0 1985648 ChemDiv2_004269 COc1ccc2n3CC(O)CN=C4CCCc(c43)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C02 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1690239 ChemDiv2_004270 CCCc1oc2cc(O)ccc2c(=O)c1Oc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C03 compound treatment 0.262 0.0275 1.48 1.4795 1.0 1985649 ChemDiv2_004271 CSc1nc(C)cc(OCCNC(=O)COc2ccc(Cl)cc2C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C04 compound treatment 0.258 0.0235 1.26 1.2645 1.0 1985650 ChemDiv2_004272 CCc1c(O)nc(SCc2ccc(F)cc2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C05 compound treatment 0.233 -0.00147 -0.08 -0.0789 -1.0 1985651 ChemDiv2_004273 COc1cc(ccc1O)C2N(CC3CCCO3)C(=O)C(=C2C(=O)c4ccco4)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C06 compound treatment 0.293 0.0585 3.15 3.1453 1.0 1504417 ChemDiv2_004274 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CNCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C07 compound treatment 0.26 0.0255 1.37 1.372 1.0 1539487 ChemDiv2_004275 Clc1ccc(CN2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C08 compound treatment 0.549 0.315 16.9 16.9023 1.0 1871600 ChemDiv2_004276 O=C(CSc1nc2ccccc2s1)Nc3ncc4C(=O)CC(Cc4n3)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C09 compound treatment 0.224 -0.0105 -0.56 -0.5626 -1.0 1088192 ChemDiv2_004277 OC1(C2CCCCC2=O)C(=O)Nc3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C10 compound treatment 0.241 0.00653 0.35 0.351 1.0 1587058 ChemDiv2_004278 CCCCC(=O)NC(c1ccccc1OC)c2cc(Cl)c3cccnc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C11 compound treatment 0.238 0.00353 0.19 0.1898 1.0 1985652 ChemDiv2_004279 CN1C(=O)c2ccc(cc2C1=O)c3nc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C12 compound treatment 0.519 0.285 15.29 15.2901 1.0 1985653 ChemDiv2_004280 CCn1cnc2cc(NC(=O)c3ccccc3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C13 compound treatment 0.5 0.266 14.27 14.2691 1.0 1985654 ChemDiv2_004281 CC1CCc2c(C1)sc3nc4c5ccccc5c(NCCCN(C)C)nn4c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C14 compound treatment 0.366 0.132 7.07 7.0682 1.0 1985655 ChemDiv2_004282 COc1ccc(cc1OC)c2cc(n[nH]2)C3CCN(CC3)c4nc(N)c5cc(OC)c(OC)cc5n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C15 compound treatment 0.246 0.0115 0.62 0.6197 1.0 1985656 ChemDiv2_004283 COc1nc(SC)nnc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C16 compound treatment 0.438 0.204 10.94 10.9373 1.0 1379718 ChemDiv2_004284 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NC3CCCCC3)OCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C17 compound treatment 0.306 0.0715 3.84 3.8439 1.0 1985657 ChemDiv2_004285 CCOC(=O)c1nn(c(C(=O)OCC)c1NC(=O)c2nn(CC)cc2Br)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C18 compound treatment 0.26 0.0255 1.37 1.372 1.0 1985658 ChemDiv2_004286 COc1ccccc1c2nc3[nH]c(C)cc(=O)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C19 compound treatment 0.262 0.0275 1.48 1.4795 1.0 1985659 ChemDiv2_004287 C=CCn1c(SCC(=O)N2CCc3ccccc23)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C20 compound treatment 0.482 0.248 13.3 13.3018 1.0 1985660 ChemDiv2_004288 CC(C)n1c2ccccc2c3nnc(SCC(=O)Nc4nc5CCCCc5s4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C21 compound treatment 0.252 0.0175 0.94 0.9421 1.0 1985661 ChemDiv2_004289 CC(C)Nc1nc(NC(C)C)nc(Oc2ccc(/C=N/O)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C22 compound treatment 0.448 0.214 11.47 11.4747 1.0 1985662 ChemDiv2_004290 COc1nnc(c2ccc(C)c(c2)S(=O)(=O)NCc3cccnc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C23 mock treatment 0.249 0.0145 0.78 0.7809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 C24 mock treatment 0.234 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D01 compound treatment 0.255 0.0205 1.1 1.1033 1.0 1985663 ChemDiv2_004291 COc1ccc(Oc2nnc(C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D02 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1985664 ChemDiv2_004292 CCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D03 compound treatment 0.33 0.0955 5.13 5.1336 1.0 1985665 ChemDiv2_004293 CC1(C)Cc2c(CO1)sc3nc(SCC(=O)Nc4ccccc4)nc(N)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D04 compound treatment 0.281 0.0465 2.5 2.5005 1.0 1985666 ChemDiv2_004294 CCOC(=O)C1=C(C)N=C2C(C1c3ccccc3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D05 compound treatment 0.222 -0.0125 -0.67 -0.67 -1.0 1985667 ChemDiv2_004295 Cc1ccc(NCc2c[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D06 compound treatment 0.332 0.0975 5.24 5.2411 1.0 1985668 ChemDiv2_004296 COC(=O)n1c(=O)oc2cc(ccc12)S(=O)(=O)Nc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D07 compound treatment 0.254 0.0195 1.05 1.0496 1.0 1985669 ChemDiv2_004297 COc1cc(ccc1OC(=O)C)C(=O)Nc2c[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D08 compound treatment 0.274 0.0395 2.12 2.1243 1.0 1460733 ChemDiv2_004298 COc1ccc(Nc2nc(=O)[nH]nc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D09 compound treatment 0.357 0.123 6.58 6.5846 1.0 1873473 ChemDiv2_004299 CC1Cc2ccccc2N1C(=O)CSC3=C(C#N)C(CC(=O)N3)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D10 compound treatment 0.405 0.171 9.16 9.164 1.0 1985670 ChemDiv2_004300 COc1cccc(OCC(O)Cn2c(Cc3ccccc3)nc4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D11 compound treatment 0.24 0.00553 0.3 0.2972 1.0 1286694 ChemDiv2_004301 CCCCC1(C)NCCN2C1SCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D12 compound treatment 0.241 0.00653 0.35 0.351 1.0 1511683 ChemDiv2_004302 Cn1c(=O)n(C)c2ncn(CCCN)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D13 compound treatment 0.51 0.276 14.81 14.8065 1.0 1985671 ChemDiv2_004303 CC1CC(CC(=O)Nc2nc(cs2)c3ccccc3)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D14 compound treatment 0.398 0.164 8.79 8.7878 1.0 1624177 ChemDiv2_004304 CCc1nc(NCC2CCCO2)c(C#N)c3CC(C)(C)OCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D15 compound treatment 0.504 0.27 14.48 14.484 1.0 1985672 ChemDiv2_004305 COc1ccc(CC(=O)Nc2nnc(s2)C3CCCCC3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D16 compound treatment 0.232 -0.00247 -0.13 -0.1327 -1.0 1985673 ChemDiv2_004306 CC(C)CCn1c(=O)c2ccccc2c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D17 compound treatment 0.461 0.227 12.17 12.1733 1.0 1530324 ChemDiv2_004307 Cc1cc(C)nc(n1)N(CCOc2ccccc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D18 compound treatment 0.318 0.0835 4.49 4.4888 1.0 1711888 ChemDiv2_004308 CN(C)c1ccc(cc1)C2Nc3ccccc3-c4nc5ccccc5n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D19 compound treatment 0.39 0.156 8.36 8.3579 1.0 1145020 ChemDiv2_004309 COc1ccc(cc1)c2cc(=O)c3cc(OC(=O)c4ccncc4)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D20 compound treatment 0.237 0.00253 0.14 0.136 1.0 1985674 ChemDiv2_004310 CCCNc1nc(=O)[nH]nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D21 compound treatment 0.451 0.217 11.64 11.6359 1.0 1546121 ChemDiv2_004311 CC(=O)n1ccc(n1)C(=O)Nc2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D22 compound treatment 0.248 0.0135 0.73 0.7271 1.0 1985675 ChemDiv2_004312 Cc1ccc(cc1CNC(=O)CSc2nc3ccccc3o2)c4nn(C)c(=O)c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D23 mock treatment 0.231 -0.00347 -0.19 -0.1864 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 D24 mock treatment 0.23 -0.00447 -0.24 -0.2401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E01 compound treatment 0.302 0.0675 3.63 3.629 1.0 1985676 ChemDiv2_004313 Cc1nnc(Nc2ccc(F)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E02 compound treatment 0.273 0.0385 2.07 2.0706 1.0 1985677 ChemDiv2_004314 Clc1ccc(OCCn2c(NC(=O)c3ccco3)nc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E03 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1874455 ChemDiv2_004315 CCCn1nc(Oc2nc(NCC)nc(NC(C)C)n2)ccc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E04 compound treatment 0.268 0.0335 1.8 1.8019 1.0 1985678 ChemDiv2_004316 COc1cc(cc(OC)c1OC)c2nc(c([nH]2)c3ccsc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E05 compound treatment 0.409 0.175 9.38 9.3789 1.0 1718030 ChemDiv2_004317 C(C1CCCCC1)c2nc(no2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E06 compound treatment 0.522 0.288 15.45 15.4513 1.0 1259652 ChemDiv2_004318 CCc1cc2c(=O)c(coc2c(CN3CCOCC3)c1O)c4cnn(c4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E07 compound treatment 0.423 0.189 10.13 10.1313 1.0 1276782 ChemDiv2_004319 Oc1ccc(Br)cc1CN2CCN(Cc3ccccc3F)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E08 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1985679 ChemDiv2_004320 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccco5)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E09 compound treatment 0.527 0.293 15.72 15.72 1.0 1266176 ChemDiv2_004321 COC(=O)c1ccc(OCC(O)Cn2cnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E10 compound treatment 0.265 0.0305 1.64 1.6407 1.0 1185080 ChemDiv2_004322 CC(C)C(=O)NC(c1ccc(C)cc1)c2cc(Cl)c3cccnc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E11 compound treatment 0.445 0.211 11.31 11.3135 1.0 1985680 ChemDiv2_004323 CCCCn1cnc2c3cc4COC(C)(C)Cc4nc3sc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E12 compound treatment 0.39 0.156 8.36 8.3579 1.0 1870263 ChemDiv2_004324 OC(COc1ccccc1)CN2C(=O)c3ccccc3S2(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E13 compound treatment 0.463 0.229 12.28 12.2808 1.0 1687449 ChemDiv2_004325 Clc1ccc(SCn2nnc3ccccc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E14 compound treatment 0.236 0.00153 0.08 0.0823 1.0 1549678 ChemDiv2_004326 CCN(c1ccccc1C(=O)O)S(=O)(=O)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E15 compound treatment 0.243 0.00853 0.46 0.4585 1.0 1558277 ChemDiv2_004327 Cc1oc2c(C)c(OC(=O)c3ccco3)ccc2c(=O)c1c4nc5ccccc5s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E16 compound treatment 0.415 0.181 9.7 9.7014 1.0 1985681 ChemDiv2_004328 CCOC(=O)[C@@H]1Nc2ccc(cc2[C@@H]3C=CC[C@@H]31)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E17 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1985682 ChemDiv2_004329 CCOC(=O)c1nn(c(C(=O)OCC)c1NC(=O)C2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E18 compound treatment 0.446 0.212 11.37 11.3672 1.0 1985683 ChemDiv2_004330 O=C(Nc1nc2nccc(c3ccccc3)n2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E19 compound treatment 0.377 0.143 7.66 7.6593 1.0 1985684 ChemDiv2_004331 COC(=O)c1ccc(Nc2nc(N3CCN(C)CC3)c4ccccc4n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E20 compound treatment 0.267 0.0325 1.75 1.7482 1.0 1132518 ChemDiv2_004332 COc1ccc2n(C)c(C)c(C(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E21 compound treatment 0.268 0.0335 1.8 1.8019 1.0 1985685 ChemDiv2_004333 CN(C)c1nc(Oc2ccc(/C=N/O)cc2)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E22 compound treatment 0.399 0.165 8.84 8.8416 1.0 1985686 ChemDiv2_004334 CCOc1ccc(cc1)c2nnc(OC)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E23 mock treatment 0.249 0.0145 0.78 0.7809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 E24 mock treatment 0.24 0.00553 0.3 0.2972 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F01 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1985687 ChemDiv2_004335 COc1ccc(Nc2nnc(C)c3ccccc23)cc1C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F02 compound treatment 0.372 0.138 7.39 7.3906 1.0 1985688 ChemDiv2_004336 Cc1c(Sc2nc3ccccc3s2)c(=O)[nH]c4cc5OCOc5cc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F03 compound treatment 0.26 0.0255 1.37 1.372 1.0 1985689 ChemDiv2_004337 CCCC(C(=O)c1ccccc1)n2cncn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F04 compound treatment 0.378 0.144 7.71 7.7131 1.0 1985690 ChemDiv2_004338 CCC(=O)Nc1cc(ccc1OC)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F05 compound treatment 0.294 0.0595 3.2 3.1991 1.0 1985691 ChemDiv2_004339 Cn1c(NCc2c[nH]c3ccccc23)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F06 compound treatment 0.284 0.0495 2.66 2.6617 1.0 1399749 ChemDiv2_004340 CCCCc1c(O)nc2SCCCn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F07 compound treatment 0.542 0.308 16.53 16.5261 1.0 1985692 ChemDiv2_004341 COc1cc(ccc1OC(=O)C)c2nc3ccc(Br)cc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F08 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1985693 ChemDiv2_004342 CS(=O)(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F09 compound treatment 0.373 0.139 7.44 7.4444 1.0 1728995 ChemDiv2_004343 CCN(CC)C(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F10 compound treatment 0.538 0.304 16.31 16.3111 1.0 1985694 ChemDiv2_004344 COc1ccc(OCC(=O)NCCSc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F11 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1186459 ChemDiv2_004345 CC1(C)CC(=O)C(CO1)C2(O)C(=O)N(Cc3ccccc3)c4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F12 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1487990 ChemDiv2_004346 COc1cc2nc(nc(N)c2cc1OC)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F13 compound treatment 0.257 0.0225 1.21 1.2108 1.0 1985695 ChemDiv2_004347 CC(CC1CC(C)OC1=O)C(=O)Nc2nncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F14 compound treatment 0.339 0.105 5.62 5.6173 1.0 1406160 ChemDiv2_004348 CCc1nc2sc3c(NCCN(C)C)ncnc3c2c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F15 compound treatment 0.433 0.199 10.67 10.6687 1.0 1861310 ChemDiv2_004349 Nc1nnc(CCC2CCCCC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F16 compound treatment 0.297 0.0625 3.36 3.3603 1.0 1214412 ChemDiv2_004350 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CNC(CO)(CO)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F17 compound treatment 0.493 0.259 13.89 13.8929 1.0 1985696 ChemDiv2_004351 Clc1ccccc1OCc2nc(C#N)c(o2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F18 compound treatment 0.405 0.171 9.16 9.164 1.0 1985697 ChemDiv2_004352 CN1C(c2ccccn2)n3c(nc4ccccc34)-c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F19 compound treatment 0.46 0.226 12.12 12.1196 1.0 1152497 ChemDiv2_004353 COc1ccc(cc1)c2cc(=O)c3cc(OCC(=O)N)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F20 compound treatment 0.35 0.116 6.21 6.2084 1.0 1650116 ChemDiv2_004354 COC(=O)C(C)Oc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F21 compound treatment 0.275 0.0405 2.18 2.1781 1.0 1985698 ChemDiv2_004355 OC(=O)CSc1cc(nc(SCC(=O)O)n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F22 compound treatment 0.252 0.0175 0.94 0.9421 1.0 1985699 ChemDiv2_004356 Cc1ccc(cc1CO)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F23 mock treatment 0.247 0.0125 0.67 0.6734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 F24 mock treatment 0.23 -0.00447 -0.24 -0.2401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G01 compound treatment 0.319 0.0845 4.54 4.5425 1.0 1947113 ChemDiv2_004357 COC(=O)c1cn(C(=O)c2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G02 compound treatment 0.313 0.0785 4.22 4.2201 1.0 1788931 ChemDiv2_004358 COc1ccc(OCCn2c(NC(=O)c3ccco3)nc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G03 compound treatment 0.228 -0.00647 -0.35 -0.3476 -1.0 1217168 ChemDiv2_004359 CC(=C1C2C=CC1C3C2C(=O)N(C3=O)c4ccc5OCOc5c4)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G04 compound treatment 0.223 -0.0115 -0.62 -0.6163 -1.0 1985700 ChemDiv2_004360 CSc1nc2nc3CC(C)(C)OCc3cc2c(=O)n1c4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G05 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1558254 ChemDiv2_004361 COc1cc(cc(OC)c1OC)C(=O)N2CCN(Cc3c[nH]c4ccccc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G06 compound treatment 0.282 0.0475 2.55 2.5542 1.0 1214433 ChemDiv2_004362 Cn1c(=O)n(C)c2nc(N3CCCC3)n(Cc4ccc(Cl)cc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G07 compound treatment 0.272 0.0375 2.02 2.0169 1.0 1985701 ChemDiv2_004363 C/C(=N\O)/CC1(O)C(=O)N(Cc2ccccc2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G08 compound treatment 0.484 0.25 13.41 13.4093 1.0 1211698 ChemDiv2_004364 C(Sc1nc2ccccc2o1)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G09 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1985702 ChemDiv2_004365 COc1ccccc1NC(=O)CSC2=NC(=O)C(Cc3ccccc3)C(=O)N2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G10 compound treatment 0.252 0.0175 0.94 0.9421 1.0 1186374 ChemDiv2_004366 CCCC(=O)NC(c1ccc(OC)c(OC)c1)c2cc(Cl)c3cccnc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G11 compound treatment 0.348 0.114 6.1 6.1009 1.0 1985703 ChemDiv2_004367 COc1cc(NC(=O)c2c(C)onc2c3ccccc3Cl)c4ncccc4c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G12 compound treatment 0.396 0.162 8.68 8.6804 1.0 1149309 ChemDiv2_004368 O=C1N(Cc2cccc3ccccc23)S(=O)(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G13 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1618203 ChemDiv2_004369 Cc1c(NC(=O)C2CCCCN2S(=O)(=O)c3ccc(Cl)cc3)c(=O)n(c4ccccc4)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G14 compound treatment 0.48 0.246 13.19 13.1943 1.0 1985704 ChemDiv2_004370 C(Sc1nc2ccccc2o1)c3nc(no3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G15 compound treatment 0.24 0.00553 0.3 0.2972 1.0 1985705 ChemDiv2_004371 CCc1c(O)nc(SCC(=O)NCC2CCCO2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G16 compound treatment 0.309 0.0745 4.01 4.0052 1.0 1985706 ChemDiv2_004372 CCOC(=O)[C@@H]1Nc2ccc(Br)cc2[C@@H]3C=CC[C@@H]31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G17 compound treatment 0.359 0.125 6.69 6.692 1.0 1659135 ChemDiv2_004373 Clc1ccc2oc(SC3=CS(=O)(=O)c4ccccc34)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G18 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1985707 ChemDiv2_004374 CC1=CC(c2ccccc2)n3nc(nc3N1)N4C(=O)c5ccccc5C4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G19 compound treatment 0.322 0.0875 4.7 4.7037 1.0 1985708 ChemDiv2_004375 CN(C)c1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G20 compound treatment 0.244 0.00953 0.51 0.5122 1.0 1985709 ChemDiv2_004376 CCOc1ccc(cc1)c2nc(NC(=O)C)c3c(=O)oc4ccccc4c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G21 compound treatment 0.316 0.0815 4.38 4.3813 1.0 1367860 ChemDiv2_004377 O=C1N(Cc2nc3ccccc3c(=O)n2CCCn4ccnc4)C(=O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G22 compound treatment 0.27 0.0355 1.91 1.9094 1.0 1985710 ChemDiv2_004378 CCN(CC)C(=O)Cn1nc(c2ccc(Cl)cc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G23 mock treatment 0.247 0.0125 0.67 0.6734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 G24 mock treatment 0.233 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H01 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1951450 ChemDiv2_004379 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H02 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1985711 ChemDiv2_004380 O=C1OC(N2CCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H03 compound treatment 0.277 0.0425 2.29 2.2855 1.0 1985712 ChemDiv2_004381 Cc1cc(OCCn2cc(/C(=N/O)/N)c3ccccc23)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H04 compound treatment 0.554 0.32 17.17 17.1709 1.0 1985713 ChemDiv2_004382 CCN(CC)C(=O)COc1ccc(cc1)c2nnc(Nc3ccc(cc3)C(=O)N)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H05 compound treatment 0.301 0.0665 3.58 3.5753 1.0 1985714 ChemDiv2_004383 CCn1c(NCc2c[nH]c3ccccc23)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H06 compound treatment 0.256 0.0215 1.16 1.157 1.0 1195379 ChemDiv2_004384 CCC(C)c1c(O)nc2SCCCn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H07 compound treatment 0.519 0.285 15.29 15.2901 1.0 1985715 ChemDiv2_004385 Cc1cc(NC(=O)c2ccc3C(=O)N(Cc4ccccc4)C(=O)c3c2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H08 compound treatment 0.282 0.0475 2.55 2.5542 1.0 1985716 ChemDiv2_004386 CCOC(=O)c1nc(Nc2ccccc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H09 compound treatment 0.365 0.131 7.01 7.0145 1.0 1985717 ChemDiv2_004387 CC1(C)Cc2nc3sc4c(ncnc4c3cc2CS1)N5CCNCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H10 compound treatment 0.478 0.244 13.09 13.0869 1.0 1930466 ChemDiv2_004388 Clc1cccc(c1)C(=O)NCCSc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H11 compound treatment 0.256 0.0215 1.16 1.157 1.0 1985718 ChemDiv2_004389 NC(=O)CN1C(=O)C2(C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H12 compound treatment 0.265 0.0305 1.64 1.6407 1.0 1985719 ChemDiv2_004390 OC(=O)CN1C(=O)SC(CC(=O)Nc2nccs2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H13 compound treatment 0.287 0.0525 2.82 2.8229 1.0 1985720 ChemDiv2_004391 Cc1cc(=O)oc2n(nc(c3ccccc3)c12)c4ccc(cc4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H14 compound treatment 0.318 0.0835 4.49 4.4888 1.0 1407465 ChemDiv2_004392 CCc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c5CCCCc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H15 compound treatment 0.561 0.327 17.55 17.5471 1.0 1985721 ChemDiv2_004393 CC(C)Cc1nnc(NC(=O)CSc2nc(=O)cc(N)n2c3ccccc3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H16 compound treatment 0.236 0.00153 0.08 0.0823 1.0 1370666 ChemDiv2_004394 Cc1c(C)c2ccccc2n1CC(O)CNC(CO)(CO)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H17 compound treatment 0.446 0.212 11.37 11.3672 1.0 1661924 ChemDiv2_004395 OC(=O)c1cccnc1SC2CC(=O)N(C2=O)c3sc4CCCCc4c3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H18 compound treatment 0.243 0.00853 0.46 0.4585 1.0 1985722 ChemDiv2_004396 OC(=O)C1C2OC3(C=C2)C(Cc4ccccc4)N(Cc5ccccc5)C(=O)C13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H19 compound treatment 0.258 0.0235 1.26 1.2645 1.0 1274035 ChemDiv2_004397 OC(=O)C(Cc1ccccc1)Nc2ncnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H20 compound treatment 0.365 0.131 7.01 7.0145 1.0 1163472 ChemDiv2_004398 O=C(CCC1CCCC1)N2CCN(Cc3c[nH]c4ccccc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H21 compound treatment 0.248 0.0135 0.73 0.7271 1.0 1985723 ChemDiv2_004399 Cn1c(=O)n(C)c2nc(Sc3nnc(N)[nH]3)n(Cc4ccccc4Cl)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H22 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1985724 ChemDiv2_004400 CC(=O)OCc1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H23 mock treatment 0.236 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 H24 mock treatment 0.224 -0.0105 -0.56 -0.5626 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I01 compound treatment 0.327 0.0925 4.97 4.9724 1.0 1137364 ChemDiv2_004401 CC1(CC2C(C(=O)Nc3nc(cs3)c4ccccc4)C(=O)N1)Oc5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I02 compound treatment 0.349 0.115 6.15 6.1547 1.0 1187273 ChemDiv2_004402 CCOC(=O)c1sc(=S)n(CC)c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I03 compound treatment 0.526 0.292 15.67 15.6663 1.0 1985725 ChemDiv2_004403 COc1ccc(Cc2nnc(SCC(=O)Nc3ccc(F)cc3)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I04 compound treatment 0.276 0.0415 2.23 2.2318 1.0 1985726 ChemDiv2_004404 CCC1(C)Cc2nc3nc(SCC(=O)OC)n(Cc4ccccc4)c(=O)c3cc2CO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I05 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1357105 ChemDiv2_004405 Cn1cccc1CN2CCN(CC2)C(=O)c3cccc(F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I06 compound treatment 0.252 0.0175 0.94 0.9421 1.0 1440377 ChemDiv2_004406 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4c2c(=O)[nH]c(=O)n4Cc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I07 compound treatment 0.379 0.145 7.77 7.7668 1.0 1276814 ChemDiv2_004407 Cc1nnc(Nc2ccc3OCOc3c2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I08 compound treatment 0.325 0.0905 4.86 4.865 1.0 1526507 ChemDiv2_004408 CCN(C(=O)CN1c2cccc3cccc(c23)S1(=O)=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I09 compound treatment 0.319 0.0845 4.54 4.5425 1.0 1789224 ChemDiv2_004409 CCC(SC1=NCCS1)C(=O)Nc2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I10 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1527103 ChemDiv2_004410 CCCCC(=O)NC(c1cccs1)c2cc(Cl)c3cccnc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I11 compound treatment 0.264 0.0295 1.59 1.5869 1.0 1653098 ChemDiv2_004411 CCN1C(=O)C2ON(C(C2C1=O)c3ccccc3)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I12 compound treatment 0.56 0.326 17.49 17.4934 1.0 1735691 ChemDiv2_004412 CCN(CC)c1ncnc2n(Cc3c(Cl)cccc3Cl)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I13 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1269149 ChemDiv2_004413 CC(C)N1C(=O)C(O)(CC(=O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I14 compound treatment 0.526 0.292 15.67 15.6663 1.0 1985727 ChemDiv2_004414 C(Sc1nc2ccccc2[nH]1)c3nc(no3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I15 compound treatment 0.243 0.00853 0.46 0.4585 1.0 1985728 ChemDiv2_004415 CCC(C)c1c(O)nc(SCC(=O)NCc2ccco2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I16 compound treatment 0.394 0.16 8.57 8.5729 1.0 1985729 ChemDiv2_004416 Cn1c(SCc2ccc(cc2)C(=O)O)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I17 compound treatment 0.276 0.0415 2.23 2.2318 1.0 1527820 ChemDiv2_004417 Cc1nc2oc(C(=O)c3ccccc3)c(N)c2c4CC(C)(C)OCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I18 compound treatment 0.311 0.0765 4.11 4.1126 1.0 1218647 ChemDiv2_004418 CCc1ccccc1NC(=O)c2cc3cccc(OC)c3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I19 compound treatment 0.238 0.00353 0.19 0.1898 1.0 1985730 ChemDiv2_004419 CN1C(=C(OC(=O)Cc2ccccc2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I20 compound treatment 0.239 0.00453 0.24 0.2435 1.0 1564217 ChemDiv2_004420 CC12C3CC(C=C3)C2C(=O)N(C1=O)c4ccc(cc4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I21 compound treatment 0.38 0.146 7.82 7.8205 1.0 1410271 ChemDiv2_004421 Nc1nc(nc(n1)c2ccccc2O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I22 compound treatment 0.241 0.00653 0.35 0.351 1.0 1985731 ChemDiv2_004422 Clc1ccc(cc1)c2nn(CC(=O)NCc3cccnc3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I23 mock treatment 0.241 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 I24 mock treatment 0.24 0.00553 0.3 0.2972 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J01 compound treatment 0.234 -4.69E-4 -0.03 -0.0252 -1.0 1170637 ChemDiv2_004423 CC1(CC(=O)O)SC(=O)NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J02 compound treatment 0.25 0.0155 0.83 0.8346 1.0 1985732 ChemDiv2_004424 COc1ccc(cc1)N2CCN(CC2)C3OC(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J03 compound treatment 0.272 0.0375 2.02 2.0169 1.0 1508106 ChemDiv2_004425 O=C(CSC1CC(=O)N(C1=O)c2ccccc2)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J04 compound treatment 0.247 0.0125 0.67 0.6734 1.0 1207778 ChemDiv2_004426 NC(=O)Cn1c(=O)sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J05 compound treatment 0.312 0.0775 4.17 4.1664 1.0 1985733 ChemDiv2_004427 CCCn1c(NCc2c[nH]c3ccccc23)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J06 compound treatment 0.243 0.00853 0.46 0.4585 1.0 1934437 ChemDiv2_004428 CCc1c(O)nc(SCC(=O)N2CCOCC2)n(c3ccccc3C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J07 compound treatment 0.536 0.302 16.2 16.2037 1.0 1985734 ChemDiv2_004429 Clc1ccccc1c2nc3cc(NC(=O)c4nc[nH]n4)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J08 compound treatment 0.247 0.0125 0.67 0.6734 1.0 1985735 ChemDiv2_004430 CCOC(=O)CSc1nnc(N)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J09 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1985736 ChemDiv2_004431 Nc1nncn1C(=O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J10 compound treatment 0.273 0.0385 2.07 2.0706 1.0 1250343 ChemDiv2_004432 O=C(N1CCCCC1)c2ccc(CN3CCc4ccccc4C3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J11 compound treatment 0.539 0.305 16.36 16.3649 1.0 1931875 ChemDiv2_004433 Cn1cnnc1SCC(=O)n2c3ccccc3c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J12 compound treatment 0.289 0.0545 2.93 2.9304 1.0 1985737 ChemDiv2_004434 Clc1ccc(CN2C(=O)SC(CC(=O)Nc3nccs3)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J13 compound treatment 0.301 0.0665 3.58 3.5753 1.0 1985738 ChemDiv2_004435 CC(C)(C)Cc1nc(no1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J14 compound treatment 0.456 0.222 11.9 11.9046 1.0 1428957 ChemDiv2_004436 CCc1nc2sc3c(NCCO)ncnc3c2c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J15 compound treatment 0.32 0.0855 4.6 4.5963 1.0 1985739 ChemDiv2_004437 CC(C)Cc1nnc(SCC(=O)Nc2ccccn2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J16 compound treatment 0.517 0.283 15.18 15.1826 1.0 1985740 ChemDiv2_004438 O=C(Nc1cccc(c1)c2cn3ccsc3n2)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J17 compound treatment 0.24 0.00553 0.3 0.2972 1.0 1985741 ChemDiv2_004439 COC(=O)C1C2OC3(CN(C(=O)C13)c4ccccc4OC)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J18 compound treatment 0.223 -0.0115 -0.62 -0.6163 -1.0 1985742 ChemDiv2_004440 COC(=O)C1C2OC3(CN(CC(C)C)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J19 compound treatment 0.295 0.0605 3.25 3.2528 1.0 1985743 ChemDiv2_004441 CC(=O)OCCNc1nc(nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J20 compound treatment 0.32 0.0855 4.6 4.5963 1.0 1985744 ChemDiv2_004442 COC(=O)C1=C(N)OC2=C(C1c3ccc(OCc4ccccc4)cc3)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J21 compound treatment 0.435 0.201 10.78 10.7761 1.0 1985745 ChemDiv2_004443 CC(=O)Nc1nnc(CCCCn2c(nc3ccccc23)c4nonc4NC(=O)C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J22 compound treatment 0.247 0.0125 0.67 0.6734 1.0 1985746 ChemDiv2_004444 Cc1ccc(cc1CN2CCCCC2)c3nn(C)c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J23 mock treatment 0.234 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 J24 mock treatment 0.227 -0.00747 -0.4 -0.4014 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K01 compound treatment 0.384 0.15 8.04 8.0355 1.0 1147858 ChemDiv2_004445 Clc1ccc(SCC(=O)Nc2cccc(c2)c3nc4ncccc4o3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K02 compound treatment 0.25 0.0155 0.83 0.8346 1.0 1985747 ChemDiv2_004446 Cc1ccc(cc1Cl)C(=O)n2cnnc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K03 compound treatment 0.437 0.203 10.88 10.8836 1.0 1985748 ChemDiv2_004447 O=C(CSc1nnc(COc2ccccc2)o1)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K04 compound treatment 0.31 0.0755 4.06 4.0589 1.0 1985749 ChemDiv2_004448 Fc1ccc(cc1)C(CC(=O)Nc2nccs2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K05 compound treatment 0.263 0.0285 1.53 1.5332 1.0 1610443 ChemDiv2_004449 COc1ccccc1C(=O)N2CCN(Cc3c[nH]c4ccccc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K06 compound treatment 0.296 0.0615 3.31 3.3066 1.0 1985750 ChemDiv2_004450 Cn1c(=O)[nH]c(=O)c2n(CCCc3ccccc3)c(nc12)N(CCO)Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K07 compound treatment 0.254 0.0195 1.05 1.0496 1.0 1269240 ChemDiv2_004451 CCOc1cc(cc(Br)c1O)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K08 compound treatment 0.567 0.333 17.87 17.8695 1.0 1985751 ChemDiv2_004452 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc(NC3=NS(=O)(=O)c4ccccc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K09 compound treatment 0.55 0.316 16.96 16.956 1.0 1985752 ChemDiv2_004453 CCC(=O)Nc1ccc2nc(SCc3nc4ccccc4[nH]3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K10 compound treatment 0.234 -4.69E-4 -0.03 -0.0252 -1.0 1985753 ChemDiv2_004454 CCc1nc2ccccc2c(=O)n1CCCCn3c(CC)nc4ccccc4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K11 compound treatment 0.29 0.0555 2.98 2.9841 1.0 1711842 ChemDiv2_004455 CCCCN1C(=O)C2ON(C(C2C1=O)c3ccco3)c4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K12 compound treatment 0.268 0.0335 1.8 1.8019 1.0 1152158 ChemDiv2_004456 COc1ccccc1Cn2cnc3n(C)c(=O)n(C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K13 compound treatment 0.241 0.00653 0.35 0.351 1.0 1985754 ChemDiv2_004457 Cc1c(N2C(C(=C(O)C2=O)C(=O)c3ccc(Br)cc3)c4cccnc4)c(=O)n(c5ccccc5)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K14 compound treatment 0.52 0.286 15.34 15.3439 1.0 1985755 ChemDiv2_004458 CCn1c(SCc2nc(no2)c3ccccc3)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K15 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1985756 ChemDiv2_004459 Oc1nc(SCC(=O)NCC2CCCO2)[nH]c(=O)c1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K16 compound treatment 0.254 0.0195 1.05 1.0496 1.0 1130530 ChemDiv2_004460 CCSc1nc2ccccc2n1CC(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K17 compound treatment 0.251 0.0165 0.89 0.8884 1.0 1281495 ChemDiv2_004461 CC1(C)CC(CC(=O)N2CCCCC2)(CCO1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K18 compound treatment 0.479 0.245 13.14 13.1406 1.0 1555590 ChemDiv2_004462 OC(=O)c1cc(NC(=O)CSc2ccccn2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K19 compound treatment 0.28 0.0455 2.45 2.4468 1.0 1985757 ChemDiv2_004463 CN1C(=C(NC(=O)c2ccccc2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K20 compound treatment 0.299 0.0645 3.47 3.4678 1.0 1985758 ChemDiv2_004464 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K21 compound treatment 0.251 0.0165 0.89 0.8884 1.0 1703314 ChemDiv2_004465 CNc1nc(C)nc(n1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K22 compound treatment 0.248 0.0135 0.73 0.7271 1.0 1985759 ChemDiv2_004466 CC(NC(=O)Cn1nc(c2ccc(Cl)cc2)c3ccccc3c1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K23 mock treatment 0.241 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 K24 mock treatment 0.234 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L01 compound treatment 0.265 0.0305 1.64 1.6407 1.0 1473335 ChemDiv2_004467 CC1N(CCc2c1[nH]c3ccccc23)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L02 compound treatment 0.437 0.203 10.88 10.8836 1.0 1985760 ChemDiv2_004468 Oc1nc(CSc2nnc(c3cccnc3)n2c4ccccc4)nc5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L03 compound treatment 0.496 0.262 14.05 14.0541 1.0 1847180 ChemDiv2_004469 Nc1c(sc2nc3CCCCCCc3cc12)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L04 compound treatment 0.286 0.0515 2.77 2.7692 1.0 1985761 ChemDiv2_004470 CC(C)c1nc(C#N)c(NCCCn2ccnc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L05 compound treatment 0.406 0.172 9.22 9.2177 1.0 1985762 ChemDiv2_004471 Oc1ccccc1CNc2nc3ccccc3n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L06 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1171628 ChemDiv2_004472 CCc1ccc2[nH]c3nc4ccccc4nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L07 compound treatment 0.264 0.0295 1.59 1.5869 1.0 1985763 ChemDiv2_004473 COC(=O)Cn1c(SC)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L08 compound treatment 0.264 0.0295 1.59 1.5869 1.0 1985764 ChemDiv2_004474 COc1ccc(cc1)c2c3C(=O)CC(C)(C)Cc3nc4sc(C(=O)N5CCOCC5)c(N)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L09 compound treatment 0.314 0.0795 4.27 4.2738 1.0 1985765 ChemDiv2_004475 CSc1nc(C)cc(Oc2ccc(=O)n(C)n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L10 compound treatment 0.277 0.0425 2.29 2.2855 1.0 1163871 ChemDiv2_004476 COc1ccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L11 compound treatment 0.374 0.14 7.5 7.4981 1.0 1724687 ChemDiv2_004477 COc1cc2nc(oc(=O)c2cc1OC)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L12 compound treatment 0.509 0.275 14.75 14.7527 1.0 1985766 ChemDiv2_004478 COc1ccccc1c2nc(SCC(=O)c3ccc(O)c(O)c3)n[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L13 compound treatment 0.331 0.0965 5.19 5.1874 1.0 1985767 ChemDiv2_004479 CC(C)C1Cc2c(CO1)sc3nc(SCC(=O)O)n(Cc4ccccc4)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L14 compound treatment 0.375 0.141 7.55 7.5519 1.0 1985768 ChemDiv2_004480 Cc1ccc2n(CC(O)Cn3c(C)cc(C)nc3=O)c4C(=O)CCCc4c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L15 compound treatment 0.256 0.0215 1.16 1.157 1.0 1044826 ChemDiv2_004481 OC(=O)CCc1ccc([nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L16 compound treatment 0.471 0.237 12.71 12.7107 1.0 1985769 ChemDiv2_004482 CCCc1nnc(NC2=NS(=O)(=O)c3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L17 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1985770 ChemDiv2_004483 COC(=O)C1C2OC3(CN(C4CCCCC4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L18 compound treatment 0.248 0.0135 0.73 0.7271 1.0 1985771 ChemDiv2_004484 COC(=O)C1C2OC3(CN(Cc4ccccc4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L19 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1182139 ChemDiv2_004485 CCOC(=O)c1cnc2ccc(Cl)cc2c1NCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L20 compound treatment 0.271 0.0365 1.96 1.9631 1.0 1875288 ChemDiv2_004486 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L21 compound treatment 0.363 0.129 6.91 6.907 1.0 1985772 ChemDiv2_004487 CN1CCc2c(C1=O)n(CC(O)Cn3nnc4ccccc34)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L22 compound treatment 0.244 0.00953 0.51 0.5122 1.0 1985773 ChemDiv2_004488 Cc1nn(CC(=O)N2CCCC2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L23 mock treatment 0.233 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 L24 mock treatment 0.222 -0.0125 -0.67 -0.67 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M01 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1430763 ChemDiv2_004489 Oc1c(ccc2cccnc12)C(NC(=O)C3CCCCC3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M02 compound treatment 0.236 0.00153 0.08 0.0823 1.0 1480832 ChemDiv2_004490 CCN1CCn2c3C1CCCc3c4cc(C)ccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M03 compound treatment 0.399 0.165 8.84 8.8416 1.0 1985774 ChemDiv2_004491 CC1CCCCC1NC(=O)CSc2nnc(COc3ccc(C)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M04 compound treatment 0.517 0.283 15.18 15.1826 1.0 1985775 ChemDiv2_004492 Cc1ccc(c2nc(no2)c3ccccn3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M05 compound treatment 0.241 0.00653 0.35 0.351 1.0 1536329 ChemDiv2_004493 COc1cccc(CN2CCN(CC2)C(=O)CC(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M06 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1985776 ChemDiv2_004494 CN1C(=O)C(C2C3CCCCC31Oc4ccccc24)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M07 compound treatment 0.289 0.0545 2.93 2.9304 1.0 1411616 ChemDiv2_004495 COc1ccccc1N2CCN(CC2)c3nc4ccccc4n5c(C)nnc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M08 compound treatment 0.53 0.296 15.88 15.8812 1.0 1985777 ChemDiv2_004496 Clc1ccc(cc1)N2CC(CC2=O)C(=O)OCCNC3=NS(=O)(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M09 compound treatment 0.485 0.251 13.46 13.463 1.0 1985778 ChemDiv2_004497 CC(C)C(=O)Nc1ccc(cc1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M10 compound treatment 0.262 0.0275 1.48 1.4795 1.0 1985779 ChemDiv2_004498 CC(=O)Nc1ccc(Oc2nc(nc3ccccc23)c4ccccc4F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M11 compound treatment 0.271 0.0365 1.96 1.9631 1.0 1375696 ChemDiv2_004499 Cc1cc(=O)oc2cc(Oc3nc(nc4ccccc34)c5cccnc5)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M12 compound treatment 0.237 0.00253 0.14 0.136 1.0 1985780 ChemDiv2_004500 Cn1c(=O)[nH]c(=O)c2n(Cc3ccccc3F)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M13 compound treatment 0.316 0.0815 4.38 4.3813 1.0 1985781 ChemDiv2_004501 CCC1S/C(=N\CC=C)/N(C1=O)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M14 compound treatment 0.459 0.225 12.07 12.0658 1.0 1985782 ChemDiv2_004502 C(Sc1nnnn1C2CCCCC2)c3nc(no3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M15 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1328510 ChemDiv2_004503 COC(=O)C1=C(C)Nc2c(C1c3ccc(Br)cc3)c(=O)n(C)c(=O)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M16 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1672502 ChemDiv2_004504 COC(=O)C(C1CCCC1)C(=O)Nc2cc(C)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M17 compound treatment 0.247 0.0125 0.67 0.6734 1.0 1985783 ChemDiv2_004505 COc1cc(CNCCC2CCOC(C)(C)C2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M18 compound treatment 0.522 0.288 15.45 15.4513 1.0 1985784 ChemDiv2_004506 CSc1nc(C)cc(SCCOC(=O)Nc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M19 compound treatment 0.267 0.0325 1.75 1.7482 1.0 1985785 ChemDiv2_004507 CCN1C(=C(NC(=O)c2ccccc2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M20 compound treatment 0.384 0.15 8.04 8.0355 1.0 1152621 ChemDiv2_004508 Cc1cc2ncn(CC(O)COCC3CCC=CC3)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M21 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1333370 ChemDiv2_004509 CCCc1nc(NC)nc(n1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M22 compound treatment 0.242 0.00753 0.4 0.4047 1.0 1985786 ChemDiv2_004510 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M23 mock treatment 0.236 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 M24 mock treatment 0.23 -0.00447 -0.24 -0.2401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N01 compound treatment 0.262 0.0275 1.48 1.4795 1.0 1985787 ChemDiv2_004511 NC(=O)CSc1nc(SCC(=O)N)c2c3CCCCc3[nH]c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N02 compound treatment 0.274 0.0395 2.12 2.1243 1.0 1985788 ChemDiv2_004512 Oc1nc(CN2CCC(Cc3ccccc3)CC2)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N03 compound treatment 0.582 0.348 18.68 18.6756 1.0 1847184 ChemDiv2_004513 CCc1nnc(NC(=O)c2sc3nc4CCCCCCc4cc3c2N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N04 compound treatment 0.28 0.0455 2.45 2.4468 1.0 1985789 ChemDiv2_004514 Nc1cc(=O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N05 compound treatment 0.306 0.0715 3.84 3.8439 1.0 1985790 ChemDiv2_004515 C=CCn1c(NCc2c[nH]c3ccccc23)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N06 compound treatment 0.318 0.0835 4.49 4.4888 1.0 1985791 ChemDiv2_004516 CCc1ccc2n(C)c3nc4ccccc4nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N07 compound treatment 0.256 0.0215 1.16 1.157 1.0 1985792 ChemDiv2_004517 CS(=O)(=O)CCC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3cccc4cccnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N08 compound treatment 0.283 0.0485 2.61 2.608 1.0 1985793 ChemDiv2_004518 O=C(CCSc1nnc2scc(c3ccccc3)n12)Nc4nc(ns4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N09 compound treatment 0.314 0.0795 4.27 4.2738 1.0 1985794 ChemDiv2_004519 O=C(NCCCN1CCOCC1)C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N10 compound treatment 0.304 0.0695 3.74 3.7365 1.0 1985795 ChemDiv2_004520 C(c1nc(no1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N11 compound treatment 0.257 0.0225 1.21 1.2108 1.0 1985796 ChemDiv2_004521 COC(=O)CSc1nc(c2ccccc2)c3cc(Cl)ccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N12 compound treatment 0.291 0.0565 3.04 3.0379 1.0 1985797 ChemDiv2_004522 Clc1ccccc1c2nc(SCC(=O)NC3CCCCC3)n[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N13 compound treatment 0.246 0.0115 0.62 0.6197 1.0 1985798 ChemDiv2_004523 COc1ccccc1NC(=O)CSc2nc3sc4COC(C)(C)Cc4c3c(=O)n2c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N14 compound treatment 0.329 0.0945 5.08 5.0799 1.0 1985799 ChemDiv2_004524 C(NC1CCCC1)c2nc(no2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N15 compound treatment 0.289 0.0545 2.93 2.9304 1.0 1985800 ChemDiv2_004525 Cc1ccc(Nc2nc(N)nc(CSc3nnnn3c4ccccc4)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N16 compound treatment 0.269 0.0345 1.86 1.8556 1.0 1162021 ChemDiv2_004526 Cc1cc2nc(SCC(=O)NCCN3CCCCC3)[nH]c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N17 compound treatment 0.326 0.0915 4.92 4.9187 1.0 1985801 ChemDiv2_004527 C(Sc1nc2cccnc2[nH]1)c3ccc(CSc4nc5cccnc5[nH]4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N18 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1985802 ChemDiv2_004528 COC(=O)C1C2OC3(CN(C(=O)C13)c4cccc(C)c4)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N19 compound treatment 0.275 0.0405 2.18 2.1781 1.0 1250041 ChemDiv2_004529 CCOC(=O)c1cnc2c(C)cc(C)cc2c1NCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N20 compound treatment 0.33 0.0955 5.13 5.1336 1.0 1875317 ChemDiv2_004530 CCn1c(N)c(sc1=S)C(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N21 compound treatment 0.257 0.0225 1.21 1.2108 1.0 1985803 ChemDiv2_004531 CN1CCc2c(C1=O)n(CC(O)CNC3CCCC3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N22 compound treatment 0.239 0.00453 0.24 0.2435 1.0 1985804 ChemDiv2_004532 O=C(Cn1nc(c2ccccc2)c3ccccc3c1=O)NCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N23 mock treatment 0.237 0.00253 0.14 0.136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 N24 mock treatment 0.216 -0.0185 -0.99 -0.9925 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O01 compound treatment 0.246 0.0115 0.62 0.6197 1.0 1551753 ChemDiv2_004533 O=S1(=O)CC(Sc2nc3ccccc3[nH]2)C=C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O02 compound treatment 0.249 0.0145 0.78 0.7809 1.0 1985805 ChemDiv2_004534 Oc1cc(=O)[nH]c(SCC(=O)NCC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O03 compound treatment 0.291 0.0565 3.04 3.0379 1.0 1985806 ChemDiv2_004535 Cc1c(C)c2ccccc2n1C(=O)CSc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O04 compound treatment 0.275 0.0405 2.18 2.1781 1.0 1557975 ChemDiv2_004536 CC(C)(C)N1COc2ccc3c4C(=O)c5ccccc5C(=O)c4oc3c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O05 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1309082 ChemDiv2_004537 CC(C)CC(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O06 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1985807 ChemDiv2_004538 Cn1c(=O)[nH]c(=O)c2n(CCOc3ccccc3)c(N)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O07 compound treatment 0.254 0.0195 1.05 1.0496 1.0 1985808 ChemDiv2_004539 CCN1CCN(CC1)c2nc3ccccc3n4c(C)nnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O08 compound treatment 0.28 0.0455 2.45 2.4468 1.0 1184970 ChemDiv2_004540 Cc1cc(C)n(n1)C(=O)CN2C(=O)CN=C(c3ccccc3)c4cc(Br)ccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O09 compound treatment 0.251 0.0165 0.89 0.8884 1.0 1182653 ChemDiv2_004541 O=C1N(C(=O)c2ncccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O10 compound treatment 0.241 0.00653 0.35 0.351 1.0 1985809 ChemDiv2_004542 COc1ccc(cc1)c2cc(nc(n2)N3CCOCC3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O11 compound treatment 0.472 0.238 12.76 12.7644 1.0 1206364 ChemDiv2_004543 O=c1c2c3CCCCc3sc2nc4ccc(nn14)N5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O12 compound treatment 0.252 0.0175 0.94 0.9421 1.0 1007732 ChemDiv2_004544 Cn1c(Oc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O13 compound treatment 0.247 0.0125 0.67 0.6734 1.0 1382933 ChemDiv2_004545 COc1cccc(c1)N(C2CS(=O)(=O)C=C2)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O14 compound treatment 0.392 0.158 8.47 8.4654 1.0 1985810 ChemDiv2_004546 C(Sc1nc2ccccc2[nH]1)Sc3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O15 compound treatment 0.255 0.0205 1.1 1.1033 1.0 1257928 ChemDiv2_004547 Clc1ccc(cc1)C2C3=C(CCCC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O16 compound treatment 0.272 0.0375 2.02 2.0169 1.0 1253894 ChemDiv2_004548 CCc1cc(=O)oc2cc3occ(C)c3cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O17 compound treatment 0.258 0.0235 1.26 1.2645 1.0 1985811 ChemDiv2_004549 OC(=O)C(Cc1ccccc1)Nc2ncnc3sc4CCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O18 compound treatment 0.315 0.0805 4.33 4.3276 1.0 1580435 ChemDiv2_004550 Clc1ccccc1Oc2coc3cc(OC(=O)OCC=C)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O19 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1985812 ChemDiv2_004551 COc1ccc(cc1)C(=O)NC2=C(N(CC=C)S(=O)(=O)c3ccccc23)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O20 compound treatment 0.462 0.228 12.23 12.2271 1.0 1985813 ChemDiv2_004552 CC(=O)Nc1ccccc1C(=O)OCC(=O)Nc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O21 compound treatment 0.259 0.0245 1.32 1.3183 1.0 1533133 ChemDiv2_004553 COC(=O)Oc1ccc2c(=O)c(Oc3ccc(C)cc3)coc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O22 compound treatment 0.261 0.0265 1.43 1.4257 1.0 1985814 ChemDiv2_004554 CCN(CC)C(=O)c1ccc(NC(=O)Cn2nc(c3ccccc3)c4ccccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O23 mock treatment 0.249 0.0145 0.78 0.7809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 O24 mock treatment 0.233 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P01 compound treatment 0.264 0.0295 1.59 1.5869 1.0 1985815 ChemDiv2_004555 COC(=O)COc1ccc(Oc2cc(C)nc(SC)n2)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P02 compound treatment 0.275 0.0405 2.18 2.1781 1.0 1871822 ChemDiv2_004556 COc1ccc(Nc2nc(N)nc(CC(=O)CSc3ccc(C)cc3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P03 compound treatment 0.267 0.0325 1.75 1.7482 1.0 1850722 ChemDiv2_004557 COc1ccc(CCNC(=O)CSc2nnc(c3ccco3)c(n2)c4ccco4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P04 compound treatment 0.375 0.141 7.55 7.5519 1.0 1882631 ChemDiv2_004558 CCC(Sc1nc(=O)cc(N)n1c2cccc(C)c2)C(=O)Nc3nnc(C)s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P05 compound treatment 0.24 0.00553 0.3 0.2972 1.0 1985816 ChemDiv2_004559 Clc1ccc(NC(=O)COc2ccccc2)cc1c3nc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P06 compound treatment 0.52 0.286 15.34 15.3439 1.0 1985817 ChemDiv2_004560 COc1cc(ccc1OC(=O)C)C(=O)Nc2cccc(c2)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P07 compound treatment 0.307 0.0725 3.9 3.8977 1.0 1985818 ChemDiv2_004561 Cn1c(=O)n(C)c2cn(cc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P08 compound treatment 0.233 -0.00147 -0.08 -0.0789 -1.0 1985819 ChemDiv2_004562 C=CCN1C(=O)C(C2C3CCCCC31Oc4ccccc24)C(=O)Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P09 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1353989 ChemDiv2_004563 COc1ccc2oc(=O)c(cc2c1)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P10 compound treatment 0.246 0.0115 0.62 0.6197 1.0 1985820 ChemDiv2_004564 CCOc1cccc2c(C)nc(Nc3nc(=O)c4CCCCc4[nH]3)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P11 compound treatment 0.32 0.0855 4.6 4.5963 1.0 1381733 ChemDiv2_004565 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3nnc(s3)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P12 compound treatment 0.345 0.111 5.94 5.9397 1.0 1985821 ChemDiv2_004566 Fc1ccccc1NC(=O)CSc2n[nH]c(n2)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P13 compound treatment 0.238 0.00353 0.19 0.1898 1.0 1985822 ChemDiv2_004567 CCC1(C)Cc2c(CO1)sc3c2c(=O)n(C)c4nnc(SCC(=O)c5ccccc5)n43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P14 compound treatment 0.24 0.00553 0.3 0.2972 1.0 1985823 ChemDiv2_004568 COc1ccc(CCN(Cc2nc(no2)c3ccccc3)Cc4nc(no4)c5ccccc5)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P15 compound treatment 0.236 0.00153 0.08 0.0823 1.0 1985824 ChemDiv2_004569 O=C(CSc1nn(c2ccccc2)c(=S)s1)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P16 compound treatment 0.253 0.0185 1.0 0.9958 1.0 1985825 ChemDiv2_004570 OC(=O)c1ccc(cc1)C2SCC(=O)N2CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P17 compound treatment 0.308 0.0735 3.95 3.9514 1.0 1289587 ChemDiv2_004571 COc1ccccc1c2coc3cc(OCC(=O)O)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P18 compound treatment 0.224 -0.0105 -0.56 -0.5626 -1.0 1985826 ChemDiv2_004572 COC(=O)C1C2OC3(CN(C(C)c4ccccc4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P19 compound treatment 0.262 0.0275 1.48 1.4795 1.0 1280425 ChemDiv2_004573 CCOC(=O)c1ccc2ncc(C(=O)OCC)c(NCCN(C)C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P20 compound treatment 0.224 -0.0105 -0.56 -0.5626 -1.0 1985827 ChemDiv2_004574 COc1ccc(NC(=O)C2C3CC(C)(Oc4ccccc34)N(C)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P21 compound treatment 0.245 0.0105 0.57 0.5659 1.0 1985828 ChemDiv2_004575 CN1CCc2c(C1=O)n(CC(O)CN(CC=C)CC=C)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P22 compound treatment 0.235 5.31E-4 0.03 0.0285 1.0 1985829 ChemDiv2_004576 O=C(Cn1nc(c2ccccc2)c3ccccc3c1=O)Nc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P23 mock treatment 0.211 -0.0235 -1.26 -1.2612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1381 P24 mock treatment 0.229 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A01 compound treatment 0.224 -0.026 -1.4 -1.3955 -1.0 1985830 ChemDiv2_004577 CC(=O)NCc1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A02 compound treatment 0.237 -0.013 -0.7 -0.6969 -1.0 1985831 ChemDiv2_004578 CCNc1nc(OC)nc(n1)N2CCC(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A03 compound treatment 0.214 -0.036 -1.93 -1.9329 -1.0 1985832 ChemDiv2_004579 CCOC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A04 compound treatment 0.217 -0.033 -1.77 -1.7717 -1.0 1985833 ChemDiv2_004580 CCOC(=O)c1cc(CC)sc1NC(=O)Cn2c(=O)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A05 compound treatment 0.322 0.072 3.87 3.8708 1.0 1985834 ChemDiv2_004581 COC(=O)C1CCN(CC1)C(=O)c2sc3ccccc3c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A06 compound treatment 0.23 -0.02 -1.07 -1.0731 -1.0 1985835 ChemDiv2_004582 OCCN(CCO)S(=O)(=O)c1cccc2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A07 compound treatment 0.246 -0.00397 -0.21 -0.2133 -1.0 1257855 ChemDiv2_004583 CCc1ccc(cc1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)NC(=O)C)c4ccccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A08 compound treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1337005 ChemDiv2_004584 CCOc1nsnc1N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A09 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1730937 ChemDiv2_004585 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)CCC(=O)O)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A10 compound treatment 0.277 0.027 1.45 1.4526 1.0 1985836 ChemDiv2_004586 COc1cccc(c1)[C@@H]2Nc3ccc(cc3[C@@H]4C=CC[C@@H]42)S(=O)(=O)Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A11 compound treatment 0.316 0.066 3.55 3.5484 1.0 1985837 ChemDiv2_004587 CN(C)C(=O)c1sc(NC(=O)C2CC2c3ccc(cc3)C(C)(C)C)nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A12 compound treatment 0.405 0.155 8.33 8.3311 1.0 1985838 ChemDiv2_004588 Nc1nc(CSc2ncccn2)nc(Nc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A13 compound treatment 0.471 0.221 11.88 11.8778 1.0 1689276 ChemDiv2_004589 COc1cccc2cc(C(=O)Nc3sc(C)c(c3C(=O)N)c4ccccc4)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A14 compound treatment 0.277 0.027 1.45 1.4526 1.0 1985839 ChemDiv2_004590 CC1CCc2c(C1)sc3nnn(CC=C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A15 compound treatment 0.249 -9.69E-4 -0.05 -0.0521 -1.0 1985840 ChemDiv2_004591 Cn1c(=O)n(C)c2cn(c(c3ccccc3)c2c1=O)C(CO)(CO)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A16 compound treatment 0.249 -9.69E-4 -0.05 -0.0521 -1.0 1985841 ChemDiv2_004592 CC1(C)CC(=O)C=C(C1)NCCN2CCN(CC2)C(=O)Cc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A17 compound treatment 0.254 0.00403 0.22 0.2166 1.0 1985842 ChemDiv2_004593 CC(C)n1c(CCC(=O)O)ccc1c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A18 compound treatment 0.253 0.00303 0.16 0.1629 1.0 1985843 ChemDiv2_004594 CCCCN(C)S(=O)(=O)c1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A19 compound treatment 0.473 0.223 11.99 11.9852 1.0 1985844 ChemDiv2_004595 CC(C)NS(=O)(=O)c1ccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A20 compound treatment 0.265 0.015 0.81 0.8077 1.0 1985845 ChemDiv2_004596 COc1ccc(cc1)C(=O)n2c(nc3ccccc23)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A21 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1985846 ChemDiv2_004597 CC(C)c1cc(C(=O)O)c2cc(Br)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A22 compound treatment 0.288 0.038 2.04 2.0437 1.0 1985847 ChemDiv2_004598 CCn1nccc1C(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A23 mock treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 A24 mock treatment 0.261 0.011 0.59 0.5928 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B01 compound treatment 0.294 0.044 2.37 2.3661 1.0 1465260 ChemDiv2_004599 O=C(N1CCN(CC1)C(=O)c2ccc(COc3ccc4CCCc4c3)o2)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B02 compound treatment 0.333 0.083 4.46 4.4619 1.0 1985848 ChemDiv2_004600 O=c1[nH]c2ccc(cc2[nH]1)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B03 compound treatment 0.229 -0.021 -1.13 -1.1268 -1.0 1165564 ChemDiv2_004601 COc1ccc(cc1)N2CC(CC2=O)C(=O)NC3CC(C)(C)NC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B04 compound treatment 0.277 0.027 1.45 1.4526 1.0 1985849 ChemDiv2_004602 CN(C1CCCCC1)C(=O)c2ccc(cc2)c3nn(C)c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B05 compound treatment 0.254 0.00403 0.22 0.2166 1.0 1985850 ChemDiv2_004603 CC(C)CCn1cnc2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B06 compound treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1985851 ChemDiv2_004604 COc1nc(NCC(C)C)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B07 compound treatment 0.234 -0.016 -0.86 -0.8581 -1.0 1985852 ChemDiv2_004605 COC(=O)C1C2OC3(CN(C(C)C)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B08 compound treatment 0.235 -0.015 -0.8 -0.8044 -1.0 1985853 ChemDiv2_004606 CC1CC(C)CN(Cc2nc(N)nc(Nc3ccccc3)n2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B09 compound treatment 0.373 0.123 6.61 6.6114 1.0 1985854 ChemDiv2_004607 Cc1cccc(C)c1N(CC(O)Cn2c3ccccc3c4ccccc24)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B10 compound treatment 0.342 0.092 4.95 4.9456 1.0 1985855 ChemDiv2_004608 Cc1nnc(SCc2cc(=O)n3ncnc3[nH]2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B11 compound treatment 0.26 0.01 0.54 0.5391 1.0 1985856 ChemDiv2_004609 CCOc1cc(ccc1OCc2cccc(F)c2)C3NC(CS3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B12 compound treatment 0.47 0.22 11.82 11.824 1.0 1985857 ChemDiv2_004610 CCCCC(=O)N1CCN(CC1)c2cc(C)c(cc2F)C(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B13 compound treatment 0.297 0.047 2.53 2.5274 1.0 1985858 ChemDiv2_004611 CCC(Oc1ccccc1)c2nc(no2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B14 compound treatment 0.285 0.035 1.88 1.8825 1.0 1985859 ChemDiv2_004612 Cc1cc(C)cc(CC(CC(=O)Nc2nccs2)C(=O)Nc3nccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B15 compound treatment 0.246 -0.00397 -0.21 -0.2133 -1.0 1985860 ChemDiv2_004613 CN(C)c1ccc(CNc2nc3ccccc3n2CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B16 compound treatment 0.412 0.162 8.71 8.7072 1.0 1985861 ChemDiv2_004614 COC(=O)CCC(=O)c1oc2ccc(Br)cc2c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B17 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1985862 ChemDiv2_004615 COc1ccc(cc1OC)S(=O)(=O)N2Cc3ccccc3CC2C(=O)N4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B18 compound treatment 0.525 0.275 14.78 14.7796 1.0 1985863 ChemDiv2_004616 Clc1ccc(cc1)C2C=C(Nc3nc(nn23)C(=O)N4CCOCC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B19 compound treatment 0.278 0.028 1.51 1.5063 1.0 1985864 ChemDiv2_004617 CC1CC(C)CN(C1)c2oc(nc2C#N)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B20 compound treatment 0.284 0.034 1.83 1.8288 1.0 1985865 ChemDiv2_004618 Nc1nc2ccccc2n1S(=O)(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B21 compound treatment 0.316 0.066 3.55 3.5484 1.0 1985866 ChemDiv2_004619 CN(Cc1ccccc1)C(=O)CN2C(=O)c3cccc4cccc2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B22 compound treatment 0.241 -0.00897 -0.48 -0.482 -1.0 1985867 ChemDiv2_004620 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)CC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B23 mock treatment 0.245 -0.00497 -0.27 -0.267 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 B24 mock treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C01 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1985868 ChemDiv2_004621 CCC(=O)NCc1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C02 compound treatment 0.264 0.014 0.75 0.754 1.0 1985869 ChemDiv2_004622 CCNc1nc(nc(n1)N2CCC(Cc3ccccc3)CC2)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C03 compound treatment 0.297 0.047 2.53 2.5274 1.0 1985870 ChemDiv2_004623 CN(C)C(=O)c1ccc(cc1)C2SCC(=O)N2CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C04 compound treatment 0.361 0.111 5.97 5.9666 1.0 1985871 ChemDiv2_004624 Cc1nnc(NC(=O)Cn2c(=O)sc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C05 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1985872 ChemDiv2_004625 Cc1cccc(N2CCN(CC2)C(=O)C3C(C4OC3C=C4)C(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C06 compound treatment 0.425 0.175 9.41 9.4058 1.0 1985873 ChemDiv2_004626 Cc1ccc(Cl)cc1NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C07 compound treatment 0.48 0.23 12.36 12.3614 1.0 1369804 ChemDiv2_004627 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C08 compound treatment 0.26 0.01 0.54 0.5391 1.0 1731466 ChemDiv2_004628 C(Oc1nsnc1N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C09 compound treatment 0.317 0.067 3.6 3.6021 1.0 1729202 ChemDiv2_004629 O=C(N1CCc2ccccc2C1)c3cc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C10 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1985874 ChemDiv2_004630 Brc1ccc(cc1)N2OC3C(C2c4cccnc4)C(=O)N(C3=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C11 compound treatment 0.379 0.129 6.93 6.9339 1.0 1985875 ChemDiv2_004631 CCOc1ccc(cc1)C(=O)Nc2cnn(Cc3ccc(F)cc3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C12 compound treatment 0.392 0.142 7.63 7.6325 1.0 1985876 ChemDiv2_004632 Cc1cc2nc(SCCOC(=O)CN3C(=O)c4ccccc4C3=O)nc(C)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C13 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1985877 ChemDiv2_004633 COC(=O)Nc1cc(C)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C14 compound treatment 0.325 0.075 4.03 4.032 1.0 1985878 ChemDiv2_004634 CCCn1nnc2sc3CC(C)CCc3c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C15 compound treatment 0.282 0.032 1.72 1.7213 1.0 1985879 ChemDiv2_004635 COc1ccc(CCn2cc3n(C)c(=O)n(C)c(=O)c3c2c4ccccc4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C16 compound treatment 0.404 0.154 8.28 8.2773 1.0 1985880 ChemDiv2_004636 CCn1c(SCc2nc(O)c3ccccc3n2)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C17 compound treatment 0.269 0.019 1.02 1.0227 1.0 1985881 ChemDiv2_004637 OC(=O)CCc1ccc(c2cccs2)n1Cc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C18 compound treatment 0.438 0.188 10.1 10.1044 1.0 1985882 ChemDiv2_004638 Cc1ccc(cc1S(=O)(=O)N2CCN(Cc3ccccc3)CC2)c4n[nH]c(=O)c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C19 compound treatment 0.273 0.023 1.24 1.2377 1.0 1985883 ChemDiv2_004639 COc1ccc(Nc2nc(nc3ccccc23)N4CCCC4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C20 compound treatment 0.272 0.022 1.18 1.1839 1.0 1985884 ChemDiv2_004640 Nc1nc(SCc2ccccc2Cl)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C21 compound treatment 0.28 0.03 1.61 1.6138 1.0 1985885 ChemDiv2_004641 CCNc1nc(Cl)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C22 compound treatment 0.308 0.058 3.12 3.1185 1.0 1985886 ChemDiv2_004642 COC(=O)c1ccccc1NC(=O)CSc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C23 mock treatment 0.26 0.01 0.54 0.5391 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 C24 mock treatment 0.249 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D01 compound treatment 0.306 0.056 3.01 3.011 1.0 1440675 ChemDiv2_004643 Brc1cnn(Cc2ccc(cc2)C(=O)N3CCN(CC3)C(=O)c4ccco4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D02 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1007736 ChemDiv2_004644 Cn1c(OCc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D03 compound treatment 0.224 -0.026 -1.4 -1.3955 -1.0 1356215 ChemDiv2_004645 S=c1sc2c(ncnc2n1c3ccccc3)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D04 compound treatment 0.265 0.015 0.81 0.8077 1.0 1985887 ChemDiv2_004646 Cn1nc(c2ccc(cc2)C(=O)NCCN3CCOCC3)c4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D05 compound treatment 0.416 0.166 8.92 8.9222 1.0 1985888 ChemDiv2_004647 COC(=O)c1ccc(NC(=O)Cn2c(nc3ccccc23)c4cncs4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D06 compound treatment 0.227 -0.023 -1.23 -1.2343 -1.0 1363845 ChemDiv2_004648 OC(=O)c1ccccc1C(=O)n2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D07 compound treatment 0.22 -0.03 -1.61 -1.6105 -1.0 1985889 ChemDiv2_004649 CCOC(=O)C1C2OC3(CN(C(=O)C13)c4ccc(Cl)c(F)c4)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D08 compound treatment 0.375 0.125 6.72 6.7189 1.0 1985890 ChemDiv2_004650 Cc1ccc(Nc2nc(N)nc(CSc3nnc(o3)c4ccncc4)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D09 compound treatment 0.245 -0.00497 -0.27 -0.267 -1.0 1985891 ChemDiv2_004651 COc1cc(cc(OC)c1OC)c2nc3n(ncc3c(=O)[nH]2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D10 compound treatment 0.262 0.012 0.65 0.6465 1.0 1985892 ChemDiv2_004652 CCN1C(=O)c2ccc(cc2C1=O)c3nc4ccccc4c(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D11 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1985893 ChemDiv2_004653 CCOC(=O)COc1ccc(cc1OC)C2NC(CS2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D12 compound treatment 0.512 0.262 14.08 14.081 1.0 1985894 ChemDiv2_004654 Cc1ccc(OCc2nc(C#N)c(NCC=C)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D13 compound treatment 0.444 0.194 10.43 10.4268 1.0 1985895 ChemDiv2_004655 Cc1nnc(SCC(=O)c2c(C)[nH]c3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D14 compound treatment 0.444 0.194 10.43 10.4268 1.0 1985896 ChemDiv2_004656 CC1(C)CC(CCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D15 compound treatment 0.479 0.229 12.31 12.3077 1.0 1985897 ChemDiv2_004657 Cc1ccc(cc1)C2N(C(=O)c3oc4ccccc4c(=O)c23)c5nccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D16 compound treatment 0.404 0.154 8.28 8.2773 1.0 1985898 ChemDiv2_004658 CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(c3ccccc3)c4ccc(O)cc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D17 compound treatment 0.268 0.018 0.97 0.969 1.0 1985899 ChemDiv2_004659 Cc1noc(C)c1CSc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D18 compound treatment 0.247 -0.00297 -0.16 -0.1595 -1.0 1985900 ChemDiv2_004660 CCS(=O)(=O)n1nc(nc1N)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D19 compound treatment 0.4 0.15 8.06 8.0624 1.0 1985901 ChemDiv2_004661 CCOc1ccc(cc1)c2nc(C#N)c(o2)N3CCN(CC)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D20 compound treatment 0.286 0.036 1.94 1.9362 1.0 1985902 ChemDiv2_004662 CCCCN1C(=O)C(O)(CC(=O)c2ccco2)c3cc(Br)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D21 compound treatment 0.26 0.01 0.54 0.5391 1.0 1985903 ChemDiv2_004663 CCOc1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D22 compound treatment 0.489 0.239 12.85 12.845 1.0 1985904 ChemDiv2_004664 CC(=O)N1CCC(CC1)C(=O)Nc2nc(ns2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D23 mock treatment 0.249 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 D24 mock treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E01 compound treatment 0.479 0.229 12.31 12.3077 1.0 1985905 ChemDiv2_004665 CCc1ccc(OCc2nc(no2)c3ccncc3)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E02 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1985906 ChemDiv2_004666 Cc1cc(NC(=O)COC(=O)Cn2ccc(=O)[nH]c2=O)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E03 compound treatment 0.273 0.023 1.24 1.2377 1.0 1985907 ChemDiv2_004667 CCN(CC)c1ncnc2c1sc3nc(C)cc(C)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E04 compound treatment 0.245 -0.00497 -0.27 -0.267 -1.0 1985908 ChemDiv2_004668 OC(=O)c1ccc(COc2ccc(cc2)C3C4=C(CCCC4=O)OC5=C3C(=O)CCC5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E05 compound treatment 0.349 0.099 5.32 5.3217 1.0 1985909 ChemDiv2_004669 NS(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc5OCOc5c4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E06 compound treatment 0.339 0.089 4.78 4.7844 1.0 1985910 ChemDiv2_004670 O=C(N1CCCCC1)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E07 compound treatment 0.233 -0.017 -0.91 -0.9119 -1.0 1307325 ChemDiv2_004671 Cc1cc(NC(=O)CCCC(=O)O)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E08 compound treatment 0.343 0.093 5.0 4.9993 1.0 1985911 ChemDiv2_004672 CCCN1C(=O)SC(CC(=O)Nc2ccccc2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E09 compound treatment 0.364 0.114 6.13 6.1278 1.0 1880677 ChemDiv2_004673 COc1cc(cc(OC)c1OC)c2cc(C(=O)O)c3cc(Br)ccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E10 compound treatment 0.234 -0.016 -0.86 -0.8581 -1.0 1985912 ChemDiv2_004674 CCN(C)CCc1c[nH]c2ccc(OC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E11 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1985913 ChemDiv2_004675 Fc1cccc(Cl)c1Cn2ccc(NC(=O)c3cc4ccccc4oc3=O)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E12 compound treatment 0.497 0.247 13.27 13.2749 1.0 1985914 ChemDiv2_004676 CN(C(=O)C(OC(=O)C)c1ccccc1)c2nnc(s2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E13 compound treatment 0.478 0.228 12.25 12.2539 1.0 1985915 ChemDiv2_004677 O=C(Nc1nnc(s1)c2ccncc2)C3c4ccccc4Oc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E14 compound treatment 0.339 0.089 4.78 4.7844 1.0 1985916 ChemDiv2_004678 O=C(Cn1nnc2sc3CCCCc3c2c1=O)OCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E15 compound treatment 0.274 0.024 1.29 1.2914 1.0 1985917 ChemDiv2_004679 Clc1ccc(cc1)c2noc(COc3ccc4OCOc4c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E16 compound treatment 0.245 -0.00497 -0.27 -0.267 -1.0 1985918 ChemDiv2_004680 Cn1c(=O)n(C)c2ncn(CC(O)CN3C(=O)c4ccccc4S3(=O)=O)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E17 compound treatment 0.263 0.013 0.7 0.7003 1.0 1985919 ChemDiv2_004681 COc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccc(cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E18 compound treatment 0.561 0.311 16.71 16.7142 1.0 1985920 ChemDiv2_004682 C(Oc1nnc(c2ccccc2)c3ccccc13)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E19 compound treatment 0.26 0.01 0.54 0.5391 1.0 1517029 ChemDiv2_004683 CC(C)NCc1c(O)c(Br)cc2oc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E20 compound treatment 0.276 0.026 1.4 1.3989 1.0 1985921 ChemDiv2_004684 Cc1ccc(CSc2n[nH]c(N)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E21 compound treatment 0.281 0.031 1.67 1.6676 1.0 1985922 ChemDiv2_004685 CC(C)(C)Nc1nc(Cl)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E22 compound treatment 0.507 0.257 13.81 13.8123 1.0 1210337 ChemDiv2_004686 Cc1ccc2nc(NC(=O)c3ccc(Cn4cc(Cl)cn4)o3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E23 mock treatment 0.258 0.00803 0.43 0.4316 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 E24 mock treatment 0.258 0.00803 0.43 0.4316 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F01 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1985923 ChemDiv2_004687 CCn1nccc1C(=O)Nc2ccc(C)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F02 compound treatment 0.264 0.014 0.75 0.754 1.0 1985924 ChemDiv2_004688 Cn1nc(c2ccc(OCC(=O)N)cc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F03 compound treatment 0.257 0.00703 0.38 0.3778 1.0 1985925 ChemDiv2_004689 Cc1c(nc(N)c(C#N)c1c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F04 compound treatment 0.321 0.071 3.82 3.8171 1.0 1985926 ChemDiv2_004690 CN(C(=O)c1ccc(cc1)c2nn(C)c(=O)c3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F05 compound treatment 0.246 -0.00397 -0.21 -0.2133 -1.0 1985927 ChemDiv2_004691 CSc1nc2sc3COC(C)(C)Cc3c2c4nnc(SCC(=O)Nc5ccccc5)n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F06 compound treatment 0.249 -9.69E-4 -0.05 -0.0521 -1.0 1985928 ChemDiv2_004692 COc1ccc(cc1)C2C(=C(Nc3ncnn23)C(C)(C)C)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F07 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1985929 ChemDiv2_004693 CCCn1c(OC)nc2n(C)c(=O)n(C)c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F08 compound treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1985930 ChemDiv2_004694 Cc1cc(C)nc(n1)N(CC(=O)N2c3ccccc3CCc4ccccc24)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F09 compound treatment 0.346 0.096 5.16 5.1605 1.0 1985931 ChemDiv2_004695 COC(=O)C(Cc1c[nH]c2ccccc12)NC3OC(=O)c4c3ccc(OC)c4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F10 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1985932 ChemDiv2_004696 CN(C)S(=O)(=O)N1CCN(CC1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F11 compound treatment 0.372 0.122 6.56 6.5577 1.0 1985933 ChemDiv2_004697 c1ccc(cc1)c2nc3[nH]c4ccccc4n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F12 compound treatment 0.512 0.262 14.08 14.081 1.0 1985934 ChemDiv2_004698 CN(Cc1ccccc1)c2oc(COc3ccccc3F)nc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F13 compound treatment 0.467 0.217 11.66 11.6628 1.0 1985935 ChemDiv2_004699 Cc1[nH]c2ccccc2c1C(=O)CSc3nnc(N)s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F14 compound treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1985936 ChemDiv2_004700 CCC(C)Nc1nc(OC)nc(Oc2ccc(O)nn2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F15 compound treatment 0.454 0.204 10.96 10.9642 1.0 1985937 ChemDiv2_004701 O=C1N(C(c2c1oc3ccccc3c2=O)c4ccncc4)c5nccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F16 compound treatment 0.273 0.023 1.24 1.2377 1.0 1985938 ChemDiv2_004702 Nc1c(oc2ccc(Br)cc12)C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F17 compound treatment 0.367 0.117 6.29 6.289 1.0 1985939 ChemDiv2_004703 Cn1c(SCCNS(=O)(=O)c2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F18 compound treatment 0.379 0.129 6.93 6.9339 1.0 1985940 ChemDiv2_004704 Nc1nc(nn1S(=O)(=O)c2ccccc2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F19 compound treatment 0.405 0.155 8.33 8.3311 1.0 1985941 ChemDiv2_004705 Cc1ccc(cc1)c2nc(C#N)c(NCCCN3CCOCC3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F20 compound treatment 0.389 0.139 7.47 7.4712 1.0 1985942 ChemDiv2_004706 COc1ccc(cc1)C2C(=C(N)Oc3c2ccc(=O)c4c(C)oc(C)c34)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F21 compound treatment 0.267 0.017 0.92 0.9152 1.0 1985943 ChemDiv2_004707 CCc1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F22 compound treatment 0.374 0.124 6.67 6.6652 1.0 1985944 ChemDiv2_004708 COCC(=O)Nc1nc(ns1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F23 mock treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 F24 mock treatment 0.255 0.00503 0.27 0.2704 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G01 compound treatment 0.351 0.101 5.43 5.4292 1.0 1985945 ChemDiv2_004709 CCc1nn2c(=O)cc(nc2s1)N3CCN(CC3)c4cc(C)nc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G02 compound treatment 0.264 0.014 0.75 0.754 1.0 1985946 ChemDiv2_004710 CCn1cc(Br)c(n1)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G03 compound treatment 0.24 -0.00997 -0.54 -0.5357 -1.0 1985947 ChemDiv2_004711 OC(=O)CCC(=O)NCC1OCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G04 compound treatment 0.282 0.032 1.72 1.7213 1.0 1985948 ChemDiv2_004712 OC(=O)COc1ccc(cc1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G05 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1985949 ChemDiv2_004713 COC(=O)c1sc(NC(=O)C2c3ccccc3Oc4ccccc24)nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G06 compound treatment 0.276 0.026 1.4 1.3989 1.0 1985950 ChemDiv2_004714 Cc1ccccc1NC(=O)C2Cc3ccccc3C(=O)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G07 compound treatment 0.415 0.165 8.87 8.8684 1.0 1399422 ChemDiv2_004715 CCN1CCN(CC1)C(=O)c2ccc(COc3ccc(Cl)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G08 compound treatment 0.477 0.227 12.2 12.2002 1.0 1292618 ChemDiv2_004716 CCOc1ccc(NC(=O)CC2SC(=O)N(C2=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G09 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1880696 ChemDiv2_004717 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCN(C/C=C/c4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G10 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1505341 ChemDiv2_004718 CCOC(=O)c1cc2ccccc2n1CCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G11 compound treatment 0.29 0.04 2.15 2.1512 1.0 1985951 ChemDiv2_004719 Cc1ccc(o1)C(=O)N2CCCN(CC2)C(=O)c3ccc(C)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G12 compound treatment 0.513 0.263 14.13 14.1347 1.0 1985952 ChemDiv2_004720 COc1ccc(cc1)C(=O)N(CC=C)c2nnc(s2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G13 compound treatment 0.246 -0.00397 -0.21 -0.2133 -1.0 1882167 ChemDiv2_004721 OC(=O)C1C(C2CCC1O2)C(=O)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G14 compound treatment 0.426 0.176 9.46 9.4596 1.0 1985953 ChemDiv2_004722 Fc1ccccc1Cn2nnc3sc4CCCCc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G15 compound treatment 0.262 0.012 0.65 0.6465 1.0 1500480 ChemDiv2_004723 CCN1C(C(C)C(=O)C(C)C1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G16 compound treatment 0.266 0.016 0.86 0.8615 1.0 1595276 ChemDiv2_004724 Cc1cccc(NCC(O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G17 compound treatment 0.263 0.013 0.7 0.7003 1.0 1985954 ChemDiv2_004725 OC(=O)CCc1ccc(c2cccs2)n1c3ccc(cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G18 compound treatment 0.315 0.065 3.49 3.4946 1.0 1985955 ChemDiv2_004726 Cc1ccc(cc1)c2nnc(OCCN3CCOCC3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G19 compound treatment 0.291 0.041 2.2 2.2049 1.0 1985956 ChemDiv2_004727 COc1ccccc1N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G20 compound treatment 0.264 0.014 0.75 0.754 1.0 1985957 ChemDiv2_004728 Nc1nc(n[nH]1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G21 compound treatment 0.281 0.031 1.67 1.6676 1.0 1985958 ChemDiv2_004729 COC(=O)Cc1[nH]nc2OC(=C(C#N)C(C3CCCC=C3)c12)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G22 compound treatment 0.266 0.016 0.86 0.8615 1.0 1717827 ChemDiv2_004730 CN1CCN(CC1)C(=O)c2ccc(Cn3cc(Cl)cn3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G23 mock treatment 0.26 0.01 0.54 0.5391 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 G24 mock treatment 0.253 0.00303 0.16 0.1629 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H01 compound treatment 0.235 -0.015 -0.8 -0.8044 -1.0 1985959 ChemDiv2_004731 CCn1ncc(Cl)c1C(=O)NC(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H02 compound treatment 0.407 0.157 8.44 8.4385 1.0 1985960 ChemDiv2_004732 CC1CCN(CC1)C(=O)COc2ccc(cc2)c3nn(C)c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H03 compound treatment 0.281 0.031 1.67 1.6676 1.0 1985961 ChemDiv2_004733 O=C(Nc1nccs1)C2CC(=O)OC2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H04 compound treatment 0.434 0.184 9.89 9.8895 1.0 1985962 ChemDiv2_004734 CCCC(=O)N1CCN(CC1)c2nnc(c3ccc(C)cc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H05 compound treatment 0.348 0.098 5.27 5.268 1.0 1985963 ChemDiv2_004735 COc1ccccc1NC(=O)CSc2nnc3c4c5CCN(C)Cc5sc4nc(SC)n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H06 compound treatment 0.282 0.032 1.72 1.7213 1.0 1985964 ChemDiv2_004736 CCSC1=NN1c2cc(C)nc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H07 compound treatment 0.255 0.00503 0.27 0.2704 1.0 1985965 ChemDiv2_004737 COc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H08 compound treatment 0.446 0.196 10.53 10.5343 1.0 1985966 ChemDiv2_004738 Cc1[nH]c2ccccc2c1C(=O)CSc3nncn3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H09 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1985967 ChemDiv2_004739 O=C(Cn1c(=O)oc2ccccc12)Nc3nc4CCCCc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H10 compound treatment 0.257 0.00703 0.38 0.3778 1.0 1985968 ChemDiv2_004740 CN(C)S(=O)(=O)N1CCN(CC1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H11 compound treatment 0.503 0.253 13.6 13.5974 1.0 1985969 ChemDiv2_004741 COC(=O)c1ccc(cc1)C(=O)Nc2ccc3[nH]c(nc3c2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H12 compound treatment 0.485 0.235 12.63 12.6301 1.0 1985970 ChemDiv2_004742 N#Cc1nc(COc2ccccc2)oc1N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H13 compound treatment 0.289 0.039 2.1 2.0975 1.0 1985971 ChemDiv2_004743 CCOC(=O)N1CCN(CC1)C(=O)C(C)(C)Oc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H14 compound treatment 0.253 0.00303 0.16 0.1629 1.0 1528125 ChemDiv2_004744 CCOC(=O)c1c(CN2CCCCC2)oc3ccc(OC)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H15 compound treatment 0.518 0.268 14.4 14.4034 1.0 1985972 ChemDiv2_004745 CCOC(=O)c1sc(nc1C)N2C(c3c(oc4ccccc4c3=O)C2=O)c5ccc(O)c(OCC)c5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H16 compound treatment 0.267 0.017 0.92 0.9152 1.0 1985973 ChemDiv2_004746 CCOC(=O)c1c(CN(CC)CC)oc2ccc(O)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H17 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1985974 ChemDiv2_004747 CC(C)(C)NC(=O)Cn1c(=O)oc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H18 compound treatment 0.262 0.012 0.65 0.6465 1.0 1985975 ChemDiv2_004748 Nc1nc(NCc2ccc(F)cc2)nn1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H19 compound treatment 0.467 0.217 11.66 11.6628 1.0 1464653 ChemDiv2_004749 COc1ccc(cc1)c2nc(C#N)c(o2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H20 compound treatment 0.284 0.034 1.83 1.8288 1.0 1985976 ChemDiv2_004750 CC1(CC2C(C(=O)OCc3ccccc3)C(=O)N1)Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H21 compound treatment 0.294 0.044 2.37 2.3661 1.0 1985977 ChemDiv2_004751 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccc(cc4)S(=O)(=O)Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H22 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1014053 ChemDiv2_004752 O=c1[nH]n(c2ccccc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H23 mock treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 H24 mock treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I01 compound treatment 0.499 0.249 13.38 13.3824 1.0 1985978 ChemDiv2_004753 CCc1nn2c(=O)cc(nc2s1)N3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I02 compound treatment 0.242 -0.00797 -0.43 -0.4282 -1.0 1985979 ChemDiv2_004754 Cc1nc2c3cc4COC(C)(C)Cc4nc3sc2c(=O)n1Cc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I03 compound treatment 0.311 0.061 3.28 3.2797 1.0 1985980 ChemDiv2_004755 COc1cc(ccc1OC(=O)C)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I04 compound treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1985981 ChemDiv2_004756 CC1(C)CC(CCO1)C(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I05 compound treatment 0.261 0.011 0.59 0.5928 1.0 1592233 ChemDiv2_004757 Cc1noc(C)c1C(=O)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I06 compound treatment 0.356 0.106 5.7 5.6979 1.0 1365319 ChemDiv2_004758 OC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I07 compound treatment 0.316 0.066 3.55 3.5484 1.0 1921120 ChemDiv2_004759 O=C(Cc1ccccc1)N2CCN(C/C=C/c3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I08 compound treatment 0.526 0.276 14.83 14.8333 1.0 1985982 ChemDiv2_004760 C=CCn1c(SCC(=O)c2ccc3cc[nH]c3c2)nnc1c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I09 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1985983 ChemDiv2_004761 OC(=O)C1C(C2CCC1O2)C(=O)Nc3cnn(Cc4ccccc4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I10 compound treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1985984 ChemDiv2_004762 Cc1cc(C)nc(NC(=N)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I11 compound treatment 0.292 0.042 2.26 2.2587 1.0 1985985 ChemDiv2_004763 Cc1ccccc1Cn2cc(NC(=O)c3cc4ccccc4oc3=O)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I12 compound treatment 0.464 0.214 11.5 11.5016 1.0 1985986 ChemDiv2_004764 Cc1nnc(SCC(=O)N2CCc3ccccc3C2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I13 compound treatment 0.326 0.076 4.09 4.0858 1.0 1882173 ChemDiv2_004765 COc1ccc(OC)c(c1)c2cc(C(=O)N3CCN(CC3)c4ncccn4)c5ccccc5n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I14 compound treatment 0.292 0.042 2.26 2.2587 1.0 1985987 ChemDiv2_004766 O=C(Cn1nnc2sc3CCCCc3c2c1=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I15 compound treatment 0.254 0.00403 0.22 0.2166 1.0 1985988 ChemDiv2_004767 CCCCn1c(CCC(=O)O)ccc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I16 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1985989 ChemDiv2_004768 CCNc1nc(N)nc(Sc2ccc(cc2)C(=O)OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I17 compound treatment 0.381 0.131 7.04 7.0413 1.0 1985990 ChemDiv2_004769 Cc1ccc(cc1C)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I18 compound treatment 0.273 0.023 1.24 1.2377 1.0 1985991 ChemDiv2_004770 Nc1cc(=O)nc(SCC(=O)Nc2ccccc2)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I19 compound treatment 0.319 0.069 3.71 3.7096 1.0 1985992 ChemDiv2_004771 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCc4cc3C#N)cc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I20 compound treatment 0.252 0.00203 0.11 0.1092 1.0 1465078 ChemDiv2_004772 Cc1cc(C)n(CC(=O)NC2CCCCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I21 compound treatment 0.418 0.168 9.03 9.0296 1.0 1985993 ChemDiv2_004773 CCOC(=O)CCc1c(C)nc(SCc2ccc(cc2)C(=O)O)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I22 compound treatment 0.419 0.169 9.08 9.0834 1.0 1572963 ChemDiv2_004774 Fc1cc(F)c(F)c(OCc2ccc(o2)C(=O)NCCc3c[nH]c4ccccc34)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I23 mock treatment 0.255 0.00503 0.27 0.2704 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 I24 mock treatment 0.252 0.00203 0.11 0.1092 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J01 compound treatment 0.33 0.08 4.3 4.3007 1.0 1985994 ChemDiv2_004775 CCn1ccc(n1)C(=O)NC2=C(CCC2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J02 compound treatment 0.328 0.078 4.19 4.1932 1.0 1985995 ChemDiv2_004776 CN(C1CCCCC1)C(=O)COc2ccc(cc2)c3nn(C)c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J03 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1985996 ChemDiv2_004777 COc1ccc2c(NCC3=CC=CC3)cc(C)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J04 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1985997 ChemDiv2_004778 CC(C)Nc1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J05 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1985998 ChemDiv2_004779 Cc1cccc(c1)n2c(SCC(=O)Nc3ccccc3)nc4nc5CC(C)(C)OCc5cc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J06 compound treatment 0.411 0.161 8.65 8.6535 1.0 1985999 ChemDiv2_004780 CN(C)c1nc(nc(n1)C(=O)Nc2ccccc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J07 compound treatment 0.261 0.011 0.59 0.5928 1.0 1986000 ChemDiv2_004781 CCCCn1c(NCCO)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J08 compound treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1986001 ChemDiv2_004782 Oc1c2C(C3=C(CCCC3=O)Nc2nn1c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J09 compound treatment 0.299 0.049 2.63 2.6348 1.0 1986002 ChemDiv2_004783 CCC(c1nc(no1)c2ccncc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J10 compound treatment 0.32 0.07 3.76 3.7633 1.0 1986003 ChemDiv2_004784 COc1cc2CCN(Cc2cc1OC)C(=O)CSc3nc4[nH]ncc4c(=O)n3c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J11 compound treatment 0.548 0.298 16.02 16.0156 1.0 1986004 ChemDiv2_004785 Nc1ccc(cc1)C(=O)Nc2ccc3[nH]c(nc3c2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J12 compound treatment 0.524 0.274 14.73 14.7259 1.0 1986005 ChemDiv2_004786 COc1ccc(Nc2oc(COc3ccccc3F)nc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J13 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1986006 ChemDiv2_004787 CCOCC(=O)Nc1cc(C)on1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J14 compound treatment 0.344 0.094 5.05 5.053 1.0 1986007 ChemDiv2_004788 CCOC(=O)c1oc2ccccc2c1CSc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J15 compound treatment 0.276 0.026 1.4 1.3989 1.0 1986008 ChemDiv2_004789 CNc1ncnc2sc(C)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J16 compound treatment 0.241 -0.00897 -0.48 -0.482 -1.0 1986009 ChemDiv2_004790 CCN1C(=O)C2(N(CCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(F)cc4)O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J17 compound treatment 0.277 0.027 1.45 1.4526 1.0 1986010 ChemDiv2_004791 CCS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J18 compound treatment 0.266 0.016 0.86 0.8615 1.0 1986011 ChemDiv2_004792 Cc1ccc(CNc2nc(N)n(n2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J19 compound treatment 0.263 0.013 0.7 0.7003 1.0 1986012 ChemDiv2_004793 CCOC(=O)N1CCC(CC1)Nc2nc(nc(n2)N3CCCC3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J20 compound treatment 0.252 0.00203 0.11 0.1092 1.0 1986013 ChemDiv2_004794 COc1ccccc1NC(=O)C2C3C4CCCCC4(NC2=O)Oc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J21 compound treatment 0.257 0.00703 0.38 0.3778 1.0 1986014 ChemDiv2_004795 O=C(CN1C(=O)c2cccc3cccc1c23)NC4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J22 compound treatment 0.302 0.052 2.8 2.7961 1.0 1986015 ChemDiv2_004796 COc1cccc(CNCCc2c[nH]c3ccccc23)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J23 mock treatment 0.242 -0.00797 -0.43 -0.4282 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 J24 mock treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K01 compound treatment 0.246 -0.00397 -0.21 -0.2133 -1.0 1986016 ChemDiv2_004797 CC(Sc1nnc2n(C)c3ccccc3n12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K02 compound treatment 0.242 -0.00797 -0.43 -0.4282 -1.0 1986017 ChemDiv2_004798 CCN(CC)c1nc(C)nc2c3cc4COC(C)(C)Cc4nc3sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K03 compound treatment 0.325 0.075 4.03 4.032 1.0 1986018 ChemDiv2_004799 Oc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ccc5ccccc5c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K04 compound treatment 0.481 0.231 12.42 12.4151 1.0 1986019 ChemDiv2_004800 COc1ccc(CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K05 compound treatment 0.374 0.124 6.67 6.6652 1.0 1412400 ChemDiv2_004801 OCCNc1cc(nc(n1)c2ccc(Br)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K06 compound treatment 0.233 -0.017 -0.91 -0.9119 -1.0 1986020 ChemDiv2_004802 Cc1ccc2n(CCN3CCOCC3)c4nc5ccccc5nc4c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K07 compound treatment 0.417 0.167 8.98 8.9759 1.0 1262411 ChemDiv2_004803 O=C(Nc1ccc(Oc2ccc(NC(=O)c3cnccn3)cc2)cc1)c4cnccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K08 compound treatment 0.343 0.093 5.0 4.9993 1.0 1986021 ChemDiv2_004804 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccnc4)C(=O)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K09 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1240871 ChemDiv2_004805 CCOC(=O)Cc1csc(NC(=O)C2CCCCC2C(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K10 compound treatment 0.432 0.182 9.78 9.782 1.0 1871768 ChemDiv2_004806 COc1cc(OC)cc(c1)C(=O)N(CC=C)c2nnc(s2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K11 compound treatment 0.323 0.073 3.92 3.9245 1.0 1986022 ChemDiv2_004807 O=C(NCc1cccc(CNC(=O)c2cnccn2)c1)c3cnccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K12 compound treatment 0.241 -0.00897 -0.48 -0.482 -1.0 1986023 ChemDiv2_004808 CC(C1SC(=O)NC1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K13 compound treatment 0.271 0.021 1.13 1.1302 1.0 1882179 ChemDiv2_004809 COC(=O)c1sccc1NC(=O)C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K14 compound treatment 0.282 0.032 1.72 1.7213 1.0 1986024 ChemDiv2_004810 O=C(Cn1nnc2sc3CCCCc3c2c1=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K15 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1986025 ChemDiv2_004811 CC(C)Cn1c(CCC(=O)O)ccc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K16 compound treatment 0.292 0.042 2.26 2.2587 1.0 1986026 ChemDiv2_004812 CCC(C)Nc1nc(SCC(=O)OC)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K17 compound treatment 0.446 0.196 10.53 10.5343 1.0 1986027 ChemDiv2_004813 Clc1ccc(cc1)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K18 compound treatment 0.287 0.037 1.99 1.99 1.0 1882583 ChemDiv2_004814 Nc1cc(=O)nc(SCC(=O)Nc2ccccc2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K19 compound treatment 0.35 0.1 5.38 5.3755 1.0 1312784 ChemDiv2_004815 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CCCCc3[nH]c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K20 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1380378 ChemDiv2_004816 CCN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K21 compound treatment 0.491 0.241 12.95 12.9525 1.0 1986028 ChemDiv2_004817 CCOC(=O)CCc1c(C)nc(SCCCn2c(=O)[nH]c3ccccc23)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K22 compound treatment 0.253 0.00303 0.16 0.1629 1.0 1986029 ChemDiv2_004818 CCn1ncc(Br)c1C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K23 mock treatment 0.254 0.00403 0.22 0.2166 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 K24 mock treatment 0.255 0.00503 0.27 0.2704 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L01 compound treatment 0.308 0.058 3.12 3.1185 1.0 1986030 ChemDiv2_004819 CCn1ccc(n1)C(=O)Nc2ccc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L02 compound treatment 0.254 0.00403 0.22 0.2166 1.0 1986031 ChemDiv2_004820 COC(=O)COc1ccc(cc1)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L03 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1986032 ChemDiv2_004821 CC(=O)Nc1cccc(Oc2nc(C)nc3sc4CCCc4c23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L04 compound treatment 0.242 -0.00797 -0.43 -0.4282 -1.0 1986033 ChemDiv2_004822 CCNc1nc(Oc2ccc(OCC)nn2)nc(n1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L05 compound treatment 0.233 -0.017 -0.91 -0.9119 -1.0 1986034 ChemDiv2_004823 CC(C)OC(=O)C1C2OC3(CN(CC4CCCO4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L06 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1986035 ChemDiv2_004824 CN(C)c1nc(nc(n1)C(=O)OCCO)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L07 compound treatment 0.405 0.155 8.33 8.3311 1.0 1986036 ChemDiv2_004825 Cc1ccc(cc1)c2cc(C(=O)OCC(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L08 compound treatment 0.275 0.025 1.35 1.3451 1.0 1986037 ChemDiv2_004826 Cc1ccc(cc1)c2nc(Nc3nc(C)cc(C)n3)n[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L09 compound treatment 0.537 0.287 15.42 15.4245 1.0 1986038 ChemDiv2_004827 NC(=O)COc1ccc(cc1)c2noc(COc3ccccc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L10 compound treatment 0.29 0.04 2.15 2.1512 1.0 1986039 ChemDiv2_004828 COCCn1c2NC3=C(C(c4ccccc4)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L11 compound treatment 0.533 0.283 15.21 15.2095 1.0 1986040 ChemDiv2_004829 Nc1cccc(c1)C(=O)Nc2ccc3[nH]c(nc3c2)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L12 compound treatment 0.254 0.00403 0.22 0.2166 1.0 1986041 ChemDiv2_004830 Oc1ccc(CN2CCCc3ccccc23)c4cccnc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L13 compound treatment 0.314 0.064 3.44 3.4409 1.0 1986042 ChemDiv2_004831 CCN(CC)S(=O)(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L14 compound treatment 0.257 0.00703 0.38 0.3778 1.0 1451904 ChemDiv2_004832 COc1cc2c(C(=O)N3CCN(C)CC3)c(C)oc2cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L15 compound treatment 0.237 -0.013 -0.7 -0.6969 -1.0 1986043 ChemDiv2_004833 Brc1ccc(cc1)N2OC3C(C2c4cccnc4)C(=O)N(C5CCCCC5)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L16 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1986044 ChemDiv2_004834 CCCN1C(=O)C2(N(CCN(C)C)C(=O)C(=C2C(=O)c3ccc(F)cc3)O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L17 compound treatment 0.24 -0.00997 -0.54 -0.5357 -1.0 1986045 ChemDiv2_004835 CCN(CC)C(=O)Cn1c(nc2ccccc12)S(=O)(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L18 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1986046 ChemDiv2_004836 Nc1nc(NCc2ccco2)nn1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L19 compound treatment 0.265 0.015 0.81 0.8077 1.0 1986047 ChemDiv2_004837 O=C(CN1C(=O)c2cccc3cccc1c23)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L20 compound treatment 0.284 0.034 1.83 1.8288 1.0 1986048 ChemDiv2_004838 Brc1ccc(NC(=O)C2C3C4CCCCC4(NC2=O)Oc5ccccc35)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L21 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1986049 ChemDiv2_004839 C=CCNC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L22 compound treatment 0.267 0.017 0.92 0.9152 1.0 1986050 ChemDiv2_004840 CN(C)c1nc(N)nc(CSc2nnc(c3cccnc3)n2CC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L23 mock treatment 0.257 0.00703 0.38 0.3778 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 L24 mock treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M01 compound treatment 0.26 0.01 0.54 0.5391 1.0 1986051 ChemDiv2_004841 OC(=O)CSc1nnc2n(CCOc3ccccc3)c4ccccc4n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M02 compound treatment 0.418 0.168 9.03 9.0296 1.0 1986052 ChemDiv2_004842 Oc1cccc(c1)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M03 compound treatment 0.28 0.03 1.61 1.6138 1.0 1986053 ChemDiv2_004843 Cc1cc(NC(=O)Cc2ccc(C)cc2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M04 compound treatment 0.247 -0.00297 -0.16 -0.1595 -1.0 1452141 ChemDiv2_004844 CN(C)C(=O)C1Cc2ccccc2CN1S(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M05 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1134920 ChemDiv2_004845 COc1ccc(cc1OC)C(=O)Oc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M06 compound treatment 0.257 0.00703 0.38 0.3778 1.0 1986054 ChemDiv2_004846 Cc1ccc2n(CC#N)c3nc4ccccc4nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M07 compound treatment 0.316 0.066 3.55 3.5484 1.0 1510264 ChemDiv2_004847 COc1ccccc1N2CCN(CC2)C(=O)CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M08 compound treatment 0.294 0.044 2.37 2.3661 1.0 1986055 ChemDiv2_004848 Nc1nc(COc2cccc3cccnc23)nc(Nc4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M09 compound treatment 0.342 0.092 4.95 4.9456 1.0 1986056 ChemDiv2_004849 Cc1onc(c1C(=O)Nc2ccn(Cc3ccc(C)cc3)n2)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M10 compound treatment 0.247 -0.00297 -0.16 -0.1595 -1.0 1986057 ChemDiv2_004850 CC(=O)OC(C(=O)Nc1nccs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M11 compound treatment 0.293 0.043 2.31 2.3124 1.0 1881582 ChemDiv2_004851 CCOc1ccccc1c2cc(C(=O)Nc3ccon3)c4ccccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M12 compound treatment 0.251 0.00103 0.06 0.0554 1.0 1986058 ChemDiv2_004852 O=c1[nH]c2SC3C4CCC(C4)C3C(c2s1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M13 compound treatment 0.377 0.127 6.83 6.8264 1.0 1986059 ChemDiv2_004853 COc1ccc(cc1)n2cc3n(C)c(=O)n(C)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M14 compound treatment 0.416 0.166 8.92 8.9222 1.0 1986060 ChemDiv2_004854 CC(C)Cc1nnc(NS(=O)(=O)c2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M15 compound treatment 0.267 0.017 0.92 0.9152 1.0 1986061 ChemDiv2_004855 OC(=O)CCc1ccc(c2ccccc2)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M16 compound treatment 0.34 0.09 4.84 4.8381 1.0 1986062 ChemDiv2_004856 C=CCOc1ccc(cc1)C(=O)N(Cc2ccccc2)C3CCS(=O)(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M17 compound treatment 0.508 0.258 13.87 13.8661 1.0 1259552 ChemDiv2_004857 Brc1cccc(c1)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M18 compound treatment 0.25 3.13E-5 0.0 0.0017 1.0 1882604 ChemDiv2_004858 Nc1cc(=O)nc(SCC(=O)NC2CCCCC2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M19 compound treatment 0.517 0.267 14.35 14.3497 1.0 1986063 ChemDiv2_004859 CC1(C)Cc2c(CO1)c(nc3sc(c(N)c23)c4ccc(o4)C(=O)O)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M20 compound treatment 0.253 0.00303 0.16 0.1629 1.0 1705917 ChemDiv2_004860 CN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M21 compound treatment 0.366 0.116 6.24 6.2353 1.0 1986064 ChemDiv2_004861 Cc1cc(NC(=O)c2sc(NCC=C)nc2N)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M22 compound treatment 0.278 0.028 1.51 1.5063 1.0 1311215 ChemDiv2_004862 CN(C)S(=O)(=O)c1cc(C(=O)N2CCN(Cc3ccccc3)CC2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M23 mock treatment 0.257 0.00703 0.38 0.3778 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 M24 mock treatment 0.253 0.00303 0.16 0.1629 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N01 compound treatment 0.273 0.023 1.24 1.2377 1.0 1986065 ChemDiv2_004863 Clc1cnn(Cc2cccc(c2)C(=O)Nc3nc4ccc(Cl)cc4s3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N02 compound treatment 0.244 -0.00597 -0.32 -0.3207 -1.0 1986066 ChemDiv2_004864 Cn1nc(c2ccc(cc2)C(=O)O)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N03 compound treatment 0.253 0.00303 0.16 0.1629 1.0 1986067 ChemDiv2_004865 OCCN1CCN(CC1)C(=O)c2cccc(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N04 compound treatment 0.24 -0.00997 -0.54 -0.5357 -1.0 1986068 ChemDiv2_004866 CC(C)(C)Nc1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N05 compound treatment 0.236 -0.014 -0.75 -0.7507 -1.0 1986069 ChemDiv2_004867 COC(=O)C1C2OC3(CN(CCc4ccccc4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N06 compound treatment 0.246 -0.00397 -0.21 -0.2133 -1.0 1986070 ChemDiv2_004868 CCNc1nc(nc(n1)C(=O)O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N07 compound treatment 0.475 0.225 12.09 12.0927 1.0 1986071 ChemDiv2_004869 Cc1cc(C)nc(SCCC(=O)OCN2C(=O)c3ccccc3C2=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N08 compound treatment 0.302 0.052 2.8 2.7961 1.0 1986072 ChemDiv2_004870 Cc1ccc(SCc2cc(=O)n3ncnc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N09 compound treatment 0.492 0.242 13.01 13.0063 1.0 1986073 ChemDiv2_004871 NC(=O)COc1ccc(cc1)c2noc(n2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N10 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1986074 ChemDiv2_004872 CCn1c2NC3=C(C(c4ccccc4)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N11 compound treatment 0.504 0.254 13.65 13.6511 1.0 1986075 ChemDiv2_004873 Fc1ccccc1C(=O)Nc2ccc3[nH]c(nc3c2)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N12 compound treatment 0.262 0.012 0.65 0.6465 1.0 1986076 ChemDiv2_004874 CCC1(C)Cc2ccccc2-c3nc(NCCO)n(c4ccccc4)c(=O)c31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N13 compound treatment 0.283 0.033 1.78 1.775 1.0 1986077 ChemDiv2_004875 CCn1c(NCc2ccc(Br)cc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N14 compound treatment 0.253 0.00303 0.16 0.1629 1.0 1784157 ChemDiv2_004876 COc1ccc2n(C)c(C)c(C(=O)N3CCN(C)CC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N15 compound treatment 0.452 0.202 10.86 10.8567 1.0 1986078 ChemDiv2_004877 Cc1cc(C)n2c(SCCN3C(=O)c4ccccc4C3=O)nnc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N16 compound treatment 0.234 -0.016 -0.86 -0.8581 -1.0 1986079 ChemDiv2_004878 CN1C(=O)C2(N(CC3CCCO3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N17 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1693306 ChemDiv2_004879 Cn1c(SCC(=O)NC(c2ccccc2)c3ccccc3)nc4n(C)c(=O)n(C)c(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N18 compound treatment 0.26 0.01 0.54 0.5391 1.0 1986080 ChemDiv2_004880 Nc1nc(NCc2cccs2)nn1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N19 compound treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1986081 ChemDiv2_004881 CCOc1ccc(NC(=O)CN2C(=O)c3cccc4cccc2c34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N20 compound treatment 0.277 0.027 1.45 1.4526 1.0 1986082 ChemDiv2_004882 CC(C)NCc1nc(no1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N21 compound treatment 0.271 0.021 1.13 1.1302 1.0 1986083 ChemDiv2_004883 COc1ccc(CCNC(=O)CN2C(=O)c3cccc4cccc2c34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N22 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1986084 ChemDiv2_004884 Nc1nc(Cc2cc3ccccc3[nH]2)nc(NC4CCCCC4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N23 mock treatment 0.249 -9.69E-4 -0.05 -0.0521 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 N24 mock treatment 0.236 -0.014 -0.75 -0.7507 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O01 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1986085 ChemDiv2_004885 CN(C)S(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O02 compound treatment 0.258 0.00803 0.43 0.4316 1.0 1986086 ChemDiv2_004886 Cc1nnc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O03 compound treatment 0.29 0.04 2.15 2.1512 1.0 1986087 ChemDiv2_004887 COCc1nnc(NC(=O)c2cccc(NC(=O)C(C)C)c2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O04 compound treatment 0.303 0.053 2.85 2.8498 1.0 1986088 ChemDiv2_004888 CN(C)CCSc1nnc2sc3ccccc3n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O05 compound treatment 0.252 0.00203 0.11 0.1092 1.0 1629645 ChemDiv2_004889 CC(Oc1ccc(Cl)cc1C)C(=O)n2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O06 compound treatment 0.252 0.00203 0.11 0.1092 1.0 1237456 ChemDiv2_004890 Cc1c(C)c2ccccc2n1CC(O)CNC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O07 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1879686 ChemDiv2_004891 Cc1cccc(N2CCN(CC2)C(=O)CCCC(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O08 compound treatment 0.273 0.023 1.24 1.2377 1.0 1986089 ChemDiv2_004892 Cc1cccc(Nc2nc(N)nc(CSc3nccn3C)n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O09 compound treatment 0.306 0.056 3.01 3.011 1.0 1881065 ChemDiv2_004893 CCn1c(NC(=O)c2cccc(Cn3cc(Cl)cn3)c2)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O10 compound treatment 0.248 -0.00197 -0.11 -0.1058 -1.0 1986090 ChemDiv2_004894 COc1ccccc1N2CCN(CC2)C(=O)C(C)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O11 compound treatment 0.307 0.057 3.06 3.0647 1.0 1696403 ChemDiv2_004895 COC(=O)c1cc(nc2ccccc12)c3cccc(N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O12 compound treatment 0.245 -0.00497 -0.27 -0.267 -1.0 1864300 ChemDiv2_004896 Cc1n[nH]c(=O)nc1NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O13 compound treatment 0.264 0.014 0.75 0.754 1.0 1986091 ChemDiv2_004897 CCOC(=O)Cn1cc2n(C)c(=O)n(C)c(=O)c2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O14 compound treatment 0.259 0.00903 0.49 0.4853 1.0 1986092 ChemDiv2_004898 Cc1cc(O)n(n1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O15 compound treatment 0.277 0.027 1.45 1.4526 1.0 1986093 ChemDiv2_004899 OC(=O)CCc1ccc(c2ccc(F)cc2)n1Cc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O16 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1986094 ChemDiv2_004900 Cc1ccc(cc1S(=O)(=O)N2CCCC2)c3nn(C)c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O17 compound treatment 0.274 0.024 1.29 1.2914 1.0 1986095 ChemDiv2_004901 CCCOc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O18 compound treatment 0.267 0.017 0.92 0.9152 1.0 1876335 ChemDiv2_004902 CC(Sc1nc(=O)cc(N)n1c2ccccc2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O19 compound treatment 0.323 0.073 3.92 3.9245 1.0 1986096 ChemDiv2_004903 Cc1ccc(cc1)C2C=C(Nc3nc(nn23)N4C(=O)CCC4=O)c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O20 compound treatment 0.261 0.011 0.59 0.5928 1.0 1986097 ChemDiv2_004904 CCOC(=O)c1sc(NC(=O)c2c(Br)cnn2CC)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O21 compound treatment 0.266 0.016 0.86 0.8615 1.0 1986098 ChemDiv2_004905 NC1=C(C#N)C(c2ccccc2Cl)c3c(O)ncnc3O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O22 compound treatment 0.282 0.032 1.72 1.7213 1.0 1986099 ChemDiv2_004906 Cn1cc(Cl)c(n1)C(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O23 mock treatment 0.261 0.011 0.59 0.5928 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 O24 mock treatment 0.256 0.00603 0.32 0.3241 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P01 compound treatment 0.469 0.219 11.77 11.7703 1.0 1986100 ChemDiv2_004907 COc1ccc(CCNC(=O)c2nn(C)cc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P02 compound treatment 0.235 -0.015 -0.8 -0.8044 -1.0 1986101 ChemDiv2_004908 CNC(=O)c1ccc(cc1)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P03 compound treatment 0.231 -0.019 -1.02 -1.0193 -1.0 1986102 ChemDiv2_004909 OCCN1CCN(CC1)C(=O)CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P04 compound treatment 0.242 -0.00797 -0.43 -0.4282 -1.0 1986103 ChemDiv2_004910 COc1nc(NCC(C)C)nc(Oc2ccc(OCc3ccccc3)nn2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P05 compound treatment 0.229 -0.021 -1.13 -1.1268 -1.0 1986104 ChemDiv2_004911 OC(=O)C1C2OC3(CN(C4CCCC4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P06 compound treatment 0.269 0.019 1.02 1.0227 1.0 1986105 ChemDiv2_004912 Nc1nc(CN2CCc3ccccc3C2)nc(Nc4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P07 compound treatment 0.272 0.022 1.18 1.1839 1.0 1986106 ChemDiv2_004913 Cc1n[nH]c(=O)nc1N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P08 compound treatment 0.293 0.043 2.31 2.3124 1.0 1986107 ChemDiv2_004914 Clc1ccc(SCc2cc(=O)n3ncnc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P09 compound treatment 0.402 0.152 8.17 8.1698 1.0 1986108 ChemDiv2_004915 COC(=O)c1ccc(COc2ccc(cc2OC)C3NC(CS3)C(=O)O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P10 compound treatment 0.298 0.048 2.58 2.5811 1.0 1986109 ChemDiv2_004916 Cc1cccc(c1)C2C3=C(Nc4c2c(=O)[nH]c(=O)n4C)c5ccccc5C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P11 compound treatment 0.326 0.076 4.09 4.0858 1.0 1986110 ChemDiv2_004917 CC(Oc1cccc(Cl)c1)c2nc(no2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P12 compound treatment 0.242 -0.00797 -0.43 -0.4282 -1.0 1986111 ChemDiv2_004918 CCC1(C)Cc2ccccc2-c3nc(c4ccccc4)n(CCO)c(=O)c31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P13 compound treatment 0.235 -0.015 -0.8 -0.8044 -1.0 1986112 ChemDiv2_004919 CC(C)n1c(NCc2ccc(cc2)N(C)C)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P14 compound treatment 0.45 0.2 10.75 10.7493 1.0 1986113 ChemDiv2_004920 COc1ccc(OC)c(c1)C(=O)c2oc3ccc(OC)cc3c2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P15 compound treatment 0.261 0.011 0.59 0.5928 1.0 1986114 ChemDiv2_004921 Cc1nnc(SCCN2C(=O)c3ccccc3C2=O)nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P16 compound treatment 0.234 -0.016 -0.86 -0.8581 -1.0 1986115 ChemDiv2_004922 Cc1ccc(cc1F)C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C42C(=O)N(CC=C)c5ccccc54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P17 compound treatment 0.235 -0.015 -0.8 -0.8044 -1.0 1211907 ChemDiv2_004923 Cn1c(SCC(=O)Nc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P18 compound treatment 0.24 -0.00997 -0.54 -0.5357 -1.0 1986116 ChemDiv2_004924 Nc1nc2ccccc2n1C(=O)CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P19 compound treatment 0.239 -0.011 -0.59 -0.5894 -1.0 1986117 ChemDiv2_004925 CCN(CC)C(=O)CN1C(=O)c2cccc3cccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P20 compound treatment 0.241 -0.00897 -0.48 -0.482 -1.0 1986118 ChemDiv2_004926 CC(C)N(Cc1nc2ccccc2[nH]1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P21 compound treatment 0.231 -0.019 -1.02 -1.0193 -1.0 1673682 ChemDiv2_004927 OC(=O)CC1SC(=O)NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P22 compound treatment 0.256 0.00603 0.32 0.3241 1.0 1986119 ChemDiv2_004928 O=C1N(C(=O)c2ccccc12)c3nc4[nH]c(cc(=O)n4n3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P23 mock treatment 0.238 -0.012 -0.64 -0.6432 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1382 P24 mock treatment 0.243 -0.00697 -0.37 -0.3745 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A01 compound treatment 0.378 0.129 6.92 6.9171 1.0 1986120 ChemDiv2_004929 O=C(Nc1nc2[nH]c(cc(=O)n2n1)c3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A02 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1986121 ChemDiv2_004930 COc1ccc(OCC(O)Cn2c(=N)n(CC=C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A03 compound treatment 0.227 -0.0223 -1.2 -1.1973 -1.0 1547468 ChemDiv2_004931 CC(C)(C)S(=O)(=O)c1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A04 compound treatment 0.369 0.12 6.43 6.4334 1.0 1986122 ChemDiv2_004932 Fc1ccc(cc1)N(Cc2nc3ccccc3[nH]2)Cc4nc5ccccc5[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A05 compound treatment 0.225 -0.0243 -1.3 -1.3048 -1.0 1986123 ChemDiv2_004933 COC(=O)c1ccccc1NC(=O)CN(c2ccccc2)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A06 compound treatment 0.234 -0.0153 -0.82 -0.8212 -1.0 1986124 ChemDiv2_004934 Oc1ccc(Oc2nc(nc(n2)N3CCCCC3)N4CCCCC4)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A07 compound treatment 0.218 -0.0313 -1.68 -1.681 -1.0 1986125 ChemDiv2_004935 Cc1cccc(NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A08 compound treatment 0.426 0.177 9.5 9.4965 1.0 1986126 ChemDiv2_004936 Cc1cccc2c(C)nc(Nc3nc(CSc4ccc(Cl)cc4)cc(=O)[nH]3)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A09 compound treatment 0.259 0.00972 0.52 0.5223 1.0 1986127 ChemDiv2_004937 Cc1ccc2n(CC(O)CNCC3CCCO3)c4CCCCc4c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A10 compound treatment 0.219 -0.0303 -1.63 -1.6273 -1.0 1986128 ChemDiv2_004938 CC(NC(=O)c1nn(C)c(=O)c2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A11 compound treatment 0.415 0.166 8.91 8.9054 1.0 1986129 ChemDiv2_004939 CCCc1nnc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A12 compound treatment 0.41 0.161 8.64 8.6367 1.0 1986130 ChemDiv2_004940 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCc5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A13 compound treatment 0.275 0.0257 1.38 1.3821 1.0 1986131 ChemDiv2_004941 Oc1ccc(cc1)C2N(C(=O)c3oc4ccccc4c(=O)c23)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A14 compound treatment 0.223 -0.0263 -1.41 -1.4123 -1.0 1986132 ChemDiv2_004942 COc1cccc2c3nc(nc(NC(=O)C)c3c(=O)oc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A15 compound treatment 0.384 0.135 7.24 7.2395 1.0 1986133 ChemDiv2_004943 COc1ccc2-c3nc(NC(=O)c4ccccc4)sc3Cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A16 compound treatment 0.444 0.195 10.46 10.4638 1.0 1986134 ChemDiv2_004944 CCOC(=O)c1c(C)n(C)c2ccc(OCC(O)Cn3nnc4ccccc34)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A17 compound treatment 0.481 0.232 12.45 12.4521 1.0 1986135 ChemDiv2_004945 CC(C)NS(=O)(=O)c1cc(ccc1C)c2nnc3c4ccccc4c(C)nn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A18 compound treatment 0.286 0.0367 1.97 1.9732 1.0 1986136 ChemDiv2_004946 CCOc1nc(ccc1c2noc(n2)c3ccco3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A19 compound treatment 0.413 0.164 8.8 8.7979 1.0 1986137 ChemDiv2_004947 C(Sc1nnc(C2CC2)n1c3ccccc3)c4nc(no4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A20 compound treatment 0.269 0.0197 1.06 1.0596 1.0 1986138 ChemDiv2_004948 OC(=O)Cn1cc(C(=O)C2CCCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A21 compound treatment 0.264 0.0147 0.79 0.791 1.0 1986139 ChemDiv2_004949 CCOC(=O)c1oc2cc(O)ccc2c(=O)c1c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A22 compound treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1986140 ChemDiv2_004950 CCC(=O)c1cn(CC(=O)N2CCOCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A23 mock treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 A24 mock treatment 0.274 0.0247 1.33 1.3283 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B01 compound treatment 0.275 0.0257 1.38 1.3821 1.0 1986141 ChemDiv2_004951 OC(=O)c1ccccc1c2cc(=O)c3cc(Cl)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B02 compound treatment 0.274 0.0247 1.33 1.3283 1.0 1574488 ChemDiv2_004952 Cn1ccnc1SCC(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B03 compound treatment 0.279 0.0297 1.6 1.597 1.0 1986142 ChemDiv2_004953 O=C(Cn1c(nc2ccccc12)c3ccccn3)NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B04 compound treatment 0.521 0.272 14.6 14.6016 1.0 1986143 ChemDiv2_004954 Cn1c2ccccc2c3nnc(SCC(=O)NC4=NC(=O)CS4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B05 compound treatment 0.54 0.291 15.62 15.6226 1.0 1986144 ChemDiv2_004955 Cc1ccc2cc(c3noc(n3)C4CCCO4)c(O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B06 compound treatment 0.261 0.0117 0.63 0.6297 1.0 1986145 ChemDiv2_004956 O=S1(=O)N=C(NC2CC2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B07 compound treatment 0.548 0.299 16.05 16.0525 1.0 1986146 ChemDiv2_004957 O=C(Nc1cccc(c1)c2nc3ncccc3o2)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B08 compound treatment 0.475 0.226 12.13 12.1297 1.0 1986147 ChemDiv2_004958 OC(CSc1nc(cc(c1C#N)c2ccccc2)c3cccs3)CN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B09 compound treatment 0.342 0.0927 4.98 4.9825 1.0 1986148 ChemDiv2_004959 CCOc1ccc(cc1OC)C2N(CC3CCCO3)C(=O)c4oc5ccc(F)cc5c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B10 compound treatment 0.352 0.103 5.52 5.5199 1.0 1125460 ChemDiv2_004960 CC(C)CN1C(=O)c2ccc(cc2C1=O)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B11 compound treatment 0.421 0.172 9.23 9.2278 1.0 1986149 ChemDiv2_004961 CCS(=O)(=O)c1nc2ccccc2n1CCOc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B12 compound treatment 0.433 0.184 9.87 9.8727 1.0 1986150 ChemDiv2_004962 CCOc1ccccc1NC(=O)CSc2nnc(o2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B13 compound treatment 0.238 -0.0113 -0.61 -0.6062 -1.0 1986151 ChemDiv2_004963 CC(NCC(O)Cn1c2ccccc2c3ccccc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B14 compound treatment 0.262 0.0127 0.68 0.6835 1.0 1694533 ChemDiv2_004964 Cc1ccccc1N2CCN(CC2)C(=O)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B15 compound treatment 0.449 0.2 10.73 10.7325 1.0 1986152 ChemDiv2_004965 CCc1nc(SCC(=O)c2ccc(C)cc2)c(C#N)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B16 compound treatment 0.243 -0.00628 -0.34 -0.3375 -1.0 1232007 ChemDiv2_004966 COc1cc2CCN=C(CC(C)C)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B17 compound treatment 0.311 0.0617 3.32 3.3166 1.0 1986153 ChemDiv2_004967 COCc1cc(C)c(C#N)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B18 compound treatment 0.367 0.118 6.33 6.326 1.0 1619243 ChemDiv2_004968 COc1cc(cc(OC)c1OC)c2nc(no2)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B19 compound treatment 0.459 0.21 11.27 11.2698 1.0 1986154 ChemDiv2_004969 O=c1cc(nc(o1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B20 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1689502 ChemDiv2_004970 Cc1cc(C)c2c(N)c(sc2n1)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B21 compound treatment 0.27 0.0207 1.11 1.1134 1.0 1146020 ChemDiv2_004971 CC(C)(C)OC(=O)NCCc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B22 compound treatment 0.257 0.00772 0.41 0.4148 1.0 1931126 ChemDiv2_004972 C(Sc1nnc[nH]1)c2ccc(CSc3nnc[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B23 mock treatment 0.251 0.00172 0.09 0.0924 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 B24 mock treatment 0.247 -0.00228 -0.12 -0.1226 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C01 compound treatment 0.281 0.0317 1.7 1.7045 1.0 1986155 ChemDiv2_004973 COc1ccc(cc1)C2C=C(Nc3nc(NC(=O)Cc4ccccc4)nn23)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C02 compound treatment 0.255 0.00572 0.31 0.3073 1.0 1986156 ChemDiv2_004974 COc1cccc(CNc2nc3ccccc3n2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C03 compound treatment 0.259 0.00972 0.52 0.5223 1.0 1986157 ChemDiv2_004975 CCOC(=O)c1c(N)nn(C(=O)C(C)C)c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C04 compound treatment 0.467 0.218 11.7 11.6998 1.0 1986158 ChemDiv2_004976 CCOC(=O)C1=C(CSc2nc(ccc2C#N)c3ccccc3)OC(=C(C#N)C1c4cccnc4)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C05 compound treatment 0.271 0.0217 1.17 1.1671 1.0 1986159 ChemDiv2_004977 Cc1ccc(cc1)N(CC(=O)Nc2ccc(F)cc2)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C06 compound treatment 0.241 -0.00828 -0.45 -0.445 -1.0 1986160 ChemDiv2_004978 Cn1nc(Oc2nc(nc(n2)N3CCCCC3)N4CCCCC4)ccc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C07 compound treatment 0.261 0.0117 0.63 0.6297 1.0 1986161 ChemDiv2_004979 COC(=O)Cn1cc(C(=O)C2CC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C08 compound treatment 0.239 -0.0103 -0.55 -0.5525 -1.0 1986162 ChemDiv2_004980 Clc1ccc2nc(Nc3nc4CCCc4c(=O)[nH]3)nc(c5ccccc5)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C09 compound treatment 0.259 0.00972 0.52 0.5223 1.0 1986163 ChemDiv2_004981 Cc1ccc2n(CC(O)CNC(C)(C)C)c3CCCCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C10 compound treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1986164 ChemDiv2_004982 Cn1nc(C(=O)NCc2cccnc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C11 compound treatment 0.553 0.304 16.32 16.3212 1.0 1986165 ChemDiv2_004983 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)OCCNC2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C12 compound treatment 0.278 0.0287 1.54 1.5433 1.0 1986166 ChemDiv2_004984 CC(Nc1nc(nc2ccccc12)N3CCN(CC3)S(=O)(=O)C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C13 compound treatment 0.347 0.0977 5.25 5.2512 1.0 1986167 ChemDiv2_004985 CCOc1ccc(cc1)C2N(C(=O)c3oc4ccccc4c(=O)c23)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C14 compound treatment 0.259 0.00972 0.52 0.5223 1.0 1986168 ChemDiv2_004986 COc1cccc2c1oc(=O)c3c(NC(=O)C)nc4CCCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C15 compound treatment 0.263 0.0137 0.74 0.7372 1.0 1986169 ChemDiv2_004987 CC(=O)Nc1ccc2OCN(Cc3ccccc3)Cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C16 compound treatment 0.356 0.107 5.73 5.7348 1.0 1986170 ChemDiv2_004988 CCOC(=O)c1c(C)n(C)c2ccc(OCC(O)CN3CCN(CCO)CC3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C17 compound treatment 0.595 0.346 18.58 18.5782 1.0 1986171 ChemDiv2_004989 CN(CCO)S(=O)(=O)c1cc(ccc1C)c2nnc3c4ccccc4c(C)nn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C18 compound treatment 0.255 0.00572 0.31 0.3073 1.0 1986172 ChemDiv2_004990 O=C(C1CCCN(C1)S(=O)(=O)Cc2ccccc2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C19 compound treatment 0.251 0.00172 0.09 0.0924 1.0 1986173 ChemDiv2_004991 CN(c1ccccc1)c2cc(=O)n(C)c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C20 compound treatment 0.274 0.0247 1.33 1.3283 1.0 1986174 ChemDiv2_004992 NC(=O)Cn1cc(C(=O)c2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C21 compound treatment 0.429 0.18 9.66 9.6577 1.0 1986175 ChemDiv2_004993 Oc1ccc2c(=O)c(coc2c1)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C22 compound treatment 0.274 0.0247 1.33 1.3283 1.0 1986176 ChemDiv2_004994 CCC(=O)c1cn(CC(=O)NCC2CCCO2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C23 mock treatment 0.256 0.00672 0.36 0.3611 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 C24 mock treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D01 compound treatment 0.359 0.11 5.9 5.8961 1.0 1986177 ChemDiv2_004995 Cc1nnc2sc(nn12)c3ccc(C)c(N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D02 compound treatment 0.237 -0.0123 -0.66 -0.66 -1.0 1330190 ChemDiv2_004996 CN1CCN(CC1)C(=O)c2cnn(c2NC(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D03 compound treatment 0.359 0.11 5.9 5.8961 1.0 1986178 ChemDiv2_004997 C(c1nnc2sc(nn12)c3ccccn3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D04 compound treatment 0.542 0.293 15.73 15.7301 1.0 1986179 ChemDiv2_004998 CCn1c2ccccc2c3nnc(SCC(=O)NC4=NC(=O)CS4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D05 compound treatment 0.512 0.263 14.12 14.118 1.0 1986180 ChemDiv2_004999 CC(C)Cc1nc(no1)c2cc3ccc(C)cc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D06 compound treatment 0.465 0.216 11.59 11.5923 1.0 1986181 ChemDiv2_005000 CCC(OC(=O)CN1C(=O)c2ccccc2C1=O)C(=O)Nc3sc4CCCCc4c3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D07 compound treatment 0.289 0.0397 2.13 2.1344 1.0 1986182 ChemDiv2_005001 COc1ccccc1CNc2nc3ccccc3n2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D08 compound treatment 0.347 0.0977 5.25 5.2512 1.0 1126086 ChemDiv2_005002 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc4ccc(Cl)cn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D09 compound treatment 0.458 0.209 11.22 11.2161 1.0 1986183 ChemDiv2_005003 COc1ccc(OCCS(=O)(=O)c2nc3ccccc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D10 compound treatment 0.236 -0.0133 -0.71 -0.7137 -1.0 1096912 ChemDiv2_005004 CN(C)c1nc2n(C)c(=O)n(C)c(=O)c2n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D11 compound treatment 0.265 0.0157 0.84 0.8447 1.0 1986184 ChemDiv2_005005 COc1ccc(cc1)N(C(=O)c2cccnc2)S(=O)(=O)c3cccc4cccnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D12 compound treatment 0.512 0.263 14.12 14.118 1.0 1946270 ChemDiv2_005006 Cc1cc(C)nc(N=c2[nH]c(=O)c3ccccc3s2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D13 compound treatment 0.251 0.00172 0.09 0.0924 1.0 1175708 ChemDiv2_005007 OC(=O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D14 compound treatment 0.254 0.00472 0.25 0.2536 1.0 1569672 ChemDiv2_005008 CCn1c(=N)n(CC(=O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D15 compound treatment 0.271 0.0217 1.17 1.1671 1.0 1986185 ChemDiv2_005009 NC(=O)c1ccc(cc1)C2SCC(=O)N2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D16 compound treatment 0.399 0.15 8.05 8.0456 1.0 1417405 ChemDiv2_005010 Clc1ccc(CSc2nc3cccnc3[nH]2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D17 compound treatment 0.279 0.0297 1.6 1.597 1.0 1579169 ChemDiv2_005011 CN(C)c1nc(nc(n1)N(C#N)S(=O)(=O)c2ccc(C)cc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D18 compound treatment 0.246 -0.00328 -0.18 -0.1763 -1.0 1127574 ChemDiv2_005012 Cn1nc(CC(=O)NCCN2C(=O)CSC2=O)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D19 compound treatment 0.317 0.0677 3.64 3.6391 1.0 1986186 ChemDiv2_005013 Nc1nc(n[nH]1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D20 compound treatment 0.399 0.15 8.05 8.0456 1.0 1126200 ChemDiv2_005014 Nc1nonc1c2noc(CCCN3C(=O)c4ccccc4C3=O)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D21 compound treatment 0.296 0.0467 2.51 2.5106 1.0 1268003 ChemDiv2_005015 Cc1cc(C)nc(SCC(=O)Oc2cccc(OC(=O)CSc3nc(C)cc(C)n3)c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D22 compound treatment 0.242 -0.00728 -0.39 -0.3913 -1.0 1935511 ChemDiv2_005016 Brc1ccc2nc(SCC(=O)NCc3ccco3)n(c4ccccc4)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D23 mock treatment 0.247 -0.00228 -0.12 -0.1226 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 D24 mock treatment 0.239 -0.0103 -0.55 -0.5525 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E01 compound treatment 0.5 0.251 13.47 13.4731 1.0 1215118 ChemDiv2_005017 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E02 compound treatment 0.252 0.00272 0.15 0.1461 1.0 1986187 ChemDiv2_005018 CCCn1c(NCc2cccc(OC)c2OC)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E03 compound treatment 0.232 -0.0173 -0.93 -0.9287 -1.0 1945983 ChemDiv2_005019 CN(C)CCSc1nc(O)c(c2ccccc2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E04 compound treatment 0.261 0.0117 0.63 0.6297 1.0 1986188 ChemDiv2_005020 CCOC(=O)CC1=C(C(C(=C(N)O1)C#N)c2ccc(C)o2)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E05 compound treatment 0.238 -0.0113 -0.61 -0.6062 -1.0 1986189 ChemDiv2_005021 NC(=O)Cn1c(nc2ccccc12)S(=O)(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E06 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1986190 ChemDiv2_005022 CN(C)c1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E07 compound treatment 0.311 0.0617 3.32 3.3166 1.0 1986191 ChemDiv2_005023 O=C(Cn1cc(C(=O)C2CC2)c3ccccc13)NCc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E08 compound treatment 0.464 0.215 11.54 11.5385 1.0 1986192 ChemDiv2_005024 CCc1nc2ccccc2n1CC(O)COc3cc(OC)cc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E09 compound treatment 0.264 0.0147 0.79 0.791 1.0 1986193 ChemDiv2_005025 COC(=O)CSc1nc(C)cc(Oc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E10 compound treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1986194 ChemDiv2_005026 Cn1nc(C(=O)NCC2CCCO2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E11 compound treatment 0.333 0.0837 4.5 4.4989 1.0 1986195 ChemDiv2_005027 OC(=O)c1c(NC(=O)Cn2c(=O)sc3ccccc23)sc4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E12 compound treatment 0.253 0.00372 0.2 0.1998 1.0 1986196 ChemDiv2_005028 CC(C)CCOc1cccc(c1)C2N(CCCN3CCOCC3)C(=O)c4oc5ccccc5c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E13 compound treatment 0.391 0.142 7.62 7.6157 1.0 1986197 ChemDiv2_005029 C=CCOc1cccc(c1)C2N(C(=O)c3oc4ccccc4c(=O)c23)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E14 compound treatment 0.249 -2.81E-4 -0.02 -0.0151 -1.0 1986198 ChemDiv2_005030 Cc1cc(C)nc(Nc2n[nH]c(Cc3ccccc3)n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E15 compound treatment 0.249 -2.81E-4 -0.02 -0.0151 -1.0 1107238 ChemDiv2_005031 COc1ccc2OCN(Cc3ccccc3)Cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E16 compound treatment 0.484 0.235 12.61 12.6133 1.0 1986199 ChemDiv2_005032 COc1nc(C)ccc1c2noc(n2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E17 compound treatment 0.555 0.306 16.43 16.4287 1.0 1986200 ChemDiv2_005033 COc1ccc(cc1S(=O)(=O)N2CCN(C)CC2)c3nnc4c5ccccc5c(C)nn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E18 compound treatment 0.292 0.0427 2.3 2.2956 1.0 1986201 ChemDiv2_005034 O=S(=O)(CC1CSc2ncnc3ncn1c23)c4ccc5ccccc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E19 compound treatment 0.254 0.00472 0.25 0.2536 1.0 1986202 ChemDiv2_005035 CCOC(=O)c1oc2c(CN3CCCCC3C)c(O)ccc2c(=O)c1c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E20 compound treatment 0.413 0.164 8.8 8.7979 1.0 1986203 ChemDiv2_005036 O=C(Cn1cc(C(=O)c2ccco2)c3ccccc13)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E21 compound treatment 0.268 0.0187 1.01 1.0059 1.0 1986204 ChemDiv2_005037 COc1ccccc1Oc2c(C)oc3cc(OC(=O)N(C)C)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E22 compound treatment 0.277 0.0277 1.49 1.4895 1.0 1986205 ChemDiv2_005038 CCC(=O)c1cn(CC(=O)NCc2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E23 mock treatment 0.247 -0.00228 -0.12 -0.1226 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 E24 mock treatment 0.252 0.00272 0.15 0.1461 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F01 compound treatment 0.295 0.0457 2.46 2.4568 1.0 1986206 ChemDiv2_005039 CC(=O)Nc1cc(ccc1C)c2nn3c(C)nnc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F02 compound treatment 0.27 0.0207 1.11 1.1134 1.0 1139756 ChemDiv2_005040 CSc1nsc(SC)c1NC(=O)OCCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F03 compound treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1986207 ChemDiv2_005041 Cc1nccn1CCc2nc(N)nc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F04 compound treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1716283 ChemDiv2_005042 CCNC(=O)C1CCCN1C(=O)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F05 compound treatment 0.577 0.328 17.61 17.6109 1.0 1986208 ChemDiv2_005043 Cc1ccc2nc(O)c(cc2c1)c3noc(n3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F06 compound treatment 0.263 0.0137 0.74 0.7372 1.0 1251351 ChemDiv2_005044 CCC(Sc1nc2ccccc2o1)C(=O)Nc3ccccc3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F07 compound treatment 0.26 0.0107 0.58 0.576 1.0 1986209 ChemDiv2_005045 CC(C)n1c(NCc2cccs2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F08 compound treatment 0.379 0.13 6.97 6.9708 1.0 1724410 ChemDiv2_005046 O=C(N1CCCc2ccccc12)c3cccc(c3)S(=O)(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F09 compound treatment 0.249 -2.81E-4 -0.02 -0.0151 -1.0 1986210 ChemDiv2_005047 CCn1c2nnc(SC(C)C(=O)O)n2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F10 compound treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1986211 ChemDiv2_005048 NC(=N)Sc1nc(nc(n1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F11 compound treatment 0.287 0.0377 2.03 2.0269 1.0 1820582 ChemDiv2_005049 Cc1cc(C)c2c(N)c(sc2n1)C(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F12 compound treatment 0.481 0.232 12.45 12.4521 1.0 1442990 ChemDiv2_005050 CC(=O)NC(=O)CSc1nc2ccccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F13 compound treatment 0.277 0.0277 1.49 1.4895 1.0 1986212 ChemDiv2_005051 OC(=O)c1cccc(NS(=O)(=O)c2cccc3cccnc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F14 compound treatment 0.284 0.0347 1.87 1.8657 1.0 1986213 ChemDiv2_005052 CCc1sc2ncnc(N(C)C)c2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F15 compound treatment 0.267 0.0177 0.95 0.9522 1.0 1986214 ChemDiv2_005053 Cn1cc(CC(=O)Nc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F16 compound treatment 0.246 -0.00328 -0.18 -0.1763 -1.0 1514368 ChemDiv2_005054 OC(=O)CCSc1cc(nc(SCCC(=O)O)n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F17 compound treatment 0.457 0.208 11.16 11.1624 1.0 1122836 ChemDiv2_005055 O=C(NC(C(=O)OCN1C(=O)c2ccccc2C1=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F18 compound treatment 0.259 0.00972 0.52 0.5223 1.0 1685243 ChemDiv2_005056 Cc1cc(C)c(C#N)c(Oc2ccc(F)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F19 compound treatment 0.25 7.19E-4 0.04 0.0386 1.0 1552710 ChemDiv2_005057 CC(C)N1C(=O)C2C3C=CC(C2C1=O)C3=C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F20 compound treatment 0.252 0.00272 0.15 0.1461 1.0 1153048 ChemDiv2_005058 CC(=O)Nc1nc(cc(c2ccco2)c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F21 compound treatment 0.334 0.0847 4.55 4.5526 1.0 1733301 ChemDiv2_005059 Cc1nnc(SCC(=O)Nc2nc(cs2)c3ccc(Br)cc3)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F22 compound treatment 0.24 -0.00928 -0.5 -0.4988 -1.0 1427954 ChemDiv2_005060 CCN(CC)c1nc2n(C)c(=O)n(C)c(=O)c2n1CC(=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F23 mock treatment 0.252 0.00272 0.15 0.1461 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 F24 mock treatment 0.237 -0.0123 -0.66 -0.66 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G01 compound treatment 0.285 0.0357 1.92 1.9195 1.0 1081217 ChemDiv2_005061 Cn1c2ccccc2c3nnc(SCCN4CCOCC4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G02 compound treatment 0.293 0.0437 2.35 2.3494 1.0 1986215 ChemDiv2_005062 CCCCn1c(NCc2cccs2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G03 compound treatment 0.24 -0.00928 -0.5 -0.4988 -1.0 1783821 ChemDiv2_005063 CCN(CC)CCSc1nc(O)c(c2ccccc2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G04 compound treatment 0.267 0.0177 0.95 0.9522 1.0 1986216 ChemDiv2_005064 Nc1nc(CSc2nc3ccccc3o2)nc(n1)c4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G05 compound treatment 0.292 0.0427 2.3 2.2956 1.0 1986217 ChemDiv2_005065 Cc1ccc(Nc2nc(=O)[nH]nc2C)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G06 compound treatment 0.264 0.0147 0.79 0.791 1.0 1986218 ChemDiv2_005066 CCNc1nc(NCC)nc(OCCNS(=O)(=O)c2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G07 compound treatment 0.247 -0.00228 -0.12 -0.1226 -1.0 1986219 ChemDiv2_005067 CCN(CC)C(=O)Cn1cc(C(=O)C2CC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G08 compound treatment 0.466 0.217 11.65 11.646 1.0 1986220 ChemDiv2_005068 COc1ccc(cc1)c2noc(CCCN3C(=O)c4ccccc4C3=O)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G09 compound treatment 0.242 -0.00728 -0.39 -0.3913 -1.0 1986221 ChemDiv2_005069 OC(=O)CCCNc1nc(Cl)nc(n1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G10 compound treatment 0.489 0.24 12.88 12.882 1.0 1986222 ChemDiv2_005070 Cn1nc(C(=O)Nc2cccnc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G11 compound treatment 0.54 0.291 15.62 15.6226 1.0 1986223 ChemDiv2_005071 CCc1nnc(NC(=O)C2Cc3ccccc3C(=O)O2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G12 compound treatment 0.333 0.0837 4.5 4.4989 1.0 1986224 ChemDiv2_005072 Oc1cccc(c1)C2N(CCCN3CCOCC3)C(=O)c4oc5ccc(F)cc5c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G13 compound treatment 0.261 0.0117 0.63 0.6297 1.0 1986225 ChemDiv2_005073 C(NCc1ccccc1)c2cn(Cc3ccccc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G14 compound treatment 0.246 -0.00328 -0.18 -0.1763 -1.0 1986226 ChemDiv2_005074 CC(Sc1nnc2sc3ccccc3n12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G15 compound treatment 0.283 0.0337 1.81 1.812 1.0 1986227 ChemDiv2_005075 OC(=O)CC1SC(=NC1=O)Nc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G16 compound treatment 0.454 0.205 11.0 11.0012 1.0 1986228 ChemDiv2_005076 COc1nc(ccc1c2noc(n2)c3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G17 compound treatment 0.563 0.314 16.86 16.8586 1.0 1986229 ChemDiv2_005077 COc1ccc(cc1S(=O)(=O)NCc2cccnc2)c3nnc4c5ccccc5c(C)nn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G18 compound treatment 0.288 0.0387 2.08 2.0807 1.0 1986230 ChemDiv2_005078 OCCNc1ncnc2c1sc3nc(c4ccccc4)c5CCCCc5c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G19 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1986231 ChemDiv2_005079 CCOC(=O)c1oc2c(CN3CCN(C)CC3)c(O)ccc2c(=O)c1c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G20 compound treatment 0.389 0.14 7.51 7.5082 1.0 1986232 ChemDiv2_005080 COC(=O)Cn1cc(C(=O)c2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G21 compound treatment 0.407 0.158 8.48 8.4755 1.0 1986233 ChemDiv2_005081 COc1ccccc1Oc2coc3cc(OCC(=O)N)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G22 compound treatment 0.273 0.0237 1.27 1.2746 1.0 1986234 ChemDiv2_005082 CCC(=O)c1cn(CC(=O)NCc2cccs2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G23 mock treatment 0.258 0.00872 0.47 0.4685 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 G24 mock treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H01 compound treatment 0.237 -0.0123 -0.66 -0.66 -1.0 1986235 ChemDiv2_005083 CC(C)CNc1nc(Oc2ccc(=O)n(C)n2)nc(n1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H02 compound treatment 0.269 0.0197 1.06 1.0596 1.0 1700534 ChemDiv2_005084 CC(=O)Oc1ccc2c(=O)oc(nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H03 compound treatment 0.28 0.0307 1.65 1.6508 1.0 1986236 ChemDiv2_005085 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccc(cc4)S(=O)(=O)N5CCCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H04 compound treatment 0.243 -0.00628 -0.34 -0.3375 -1.0 1471373 ChemDiv2_005086 O=C(CSc1nc[nH]n1)NC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H05 compound treatment 0.572 0.323 17.34 17.3422 1.0 1986237 ChemDiv2_005087 CC(C)c1nc(no1)c2cc3cc(C)ccc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H06 compound treatment 0.395 0.146 7.83 7.8306 1.0 1739657 ChemDiv2_005088 CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H07 compound treatment 0.326 0.0767 4.12 4.1227 1.0 1986238 ChemDiv2_005089 Cn1c(CNc2nc3ccccc3n2CCN4CCCCC4)nc5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H08 compound treatment 0.255 0.00572 0.31 0.3073 1.0 1384173 ChemDiv2_005090 CC(C)(CO)NC(=O)c1cccc(c1)S(=O)(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H09 compound treatment 0.347 0.0977 5.25 5.2512 1.0 1986239 ChemDiv2_005091 CCn1c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H10 compound treatment 0.269 0.0197 1.06 1.0596 1.0 1986240 ChemDiv2_005092 ClCCCC(=O)N1CCc2[nH]c3ccccc3c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H11 compound treatment 0.264 0.0147 0.79 0.791 1.0 1986241 ChemDiv2_005093 Cc1ccc2oc(c(O)c(=O)c2c1)c3ccc(Cl)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H12 compound treatment 0.373 0.124 6.65 6.6484 1.0 1618540 ChemDiv2_005094 CCCCN1C(C(=C(O)C1=O)C(=O)c2ccc(OC)cc2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H13 compound treatment 0.454 0.205 11.0 11.0012 1.0 1986242 ChemDiv2_005095 O=C(CSc1ncnc2[nH]cnc12)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H14 compound treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1526356 ChemDiv2_005096 CCN(CC)C(=O)c1cccnc1Oc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H15 compound treatment 0.249 -2.81E-4 -0.02 -0.0151 -1.0 1528101 ChemDiv2_005097 COc1ccccc1n2c(=O)c3cc4c(=O)n(c5ccccc5OC)c(=O)c4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H16 compound treatment 0.275 0.0257 1.38 1.3821 1.0 1669249 ChemDiv2_005098 Nc1nonc1C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H17 compound treatment 0.508 0.259 13.9 13.903 1.0 1569150 ChemDiv2_005099 Cc1ccc(cc1)C(=O)c2sc3nc(C)ccc3c2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H18 compound treatment 0.265 0.0157 0.84 0.8447 1.0 1986243 ChemDiv2_005100 NC(=O)CSc1nc(N)cc(O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H19 compound treatment 0.301 0.0517 2.78 2.7793 1.0 1986244 ChemDiv2_005101 Cc1cc(C)c(C#N)c(SCC(=O)NC2CC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H20 compound treatment 0.247 -0.00228 -0.12 -0.1226 -1.0 1603284 ChemDiv2_005102 CCC1(CC)OC(Nc2ccccc21)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H21 compound treatment 0.301 0.0517 2.78 2.7793 1.0 1327650 ChemDiv2_005103 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc3ccccc3)Oc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H22 compound treatment 0.267 0.0177 0.95 0.9522 1.0 1986245 ChemDiv2_005104 O=C(CSc1nnc(c2ccccc2)n1Cc3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H23 mock treatment 0.254 0.00472 0.25 0.2536 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 H24 mock treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I01 compound treatment 0.253 0.00372 0.2 0.1998 1.0 1402990 ChemDiv2_005105 Cc1c(NC(=O)CSc2nnc3c4ccccc4n(CC=C)c3n2)c(=O)n(c5ccccc5)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I02 compound treatment 0.249 -2.81E-4 -0.02 -0.0151 -1.0 1986246 ChemDiv2_005106 CCN(CC)CCn1c(NCc2ccccc2OC)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I03 compound treatment 0.236 -0.0133 -0.71 -0.7137 -1.0 1986247 ChemDiv2_005107 Oc1nc(SCCN2CCOCC2)[nH]c(=O)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I04 compound treatment 0.237 -0.0123 -0.66 -0.66 -1.0 718 ChemDiv2_005108 Cn1c(=O)n(C)c2ncn(CCO)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I05 compound treatment 0.251 0.00172 0.09 0.0924 1.0 1986248 ChemDiv2_005109 Cc1ccc2oc(cc(=O)c2c1)c3ccccc3C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I06 compound treatment 0.275 0.0257 1.38 1.3821 1.0 1986249 ChemDiv2_005110 CC(C)Nc1nc(Nc2cccc(C)c2)nc(Oc3ccc(=O)n(C)n3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I07 compound treatment 0.246 -0.00328 -0.18 -0.1763 -1.0 1986250 ChemDiv2_005111 CC1CCCC(C)N1C(=O)Cn2cc(C(=O)C3CC3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I08 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1986251 ChemDiv2_005112 O=c1[nH]cnc2c1sc3nc(N4CCCCC4)c5CCCCc5c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I09 compound treatment 0.257 0.00772 0.41 0.4148 1.0 1986252 ChemDiv2_005113 CSc1nc(C)cc(OCC(=O)N2CCOCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I10 compound treatment 0.237 -0.0123 -0.66 -0.66 -1.0 1986253 ChemDiv2_005114 Cn1nc(C(=O)NCCN2CCOCC2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I11 compound treatment 0.447 0.198 10.62 10.625 1.0 1986254 ChemDiv2_005115 O=C1OC(Cc2ccccc12)c3nn4c(nnc4s3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I12 compound treatment 0.269 0.0197 1.06 1.0596 1.0 1986255 ChemDiv2_005116 COCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4ccc(cc4)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I13 compound treatment 0.271 0.0217 1.17 1.1671 1.0 1986256 ChemDiv2_005117 COC(=O)C1Cc2cc(OC)c(OC)cc2C(=N1)Cc3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I14 compound treatment 0.261 0.0117 0.63 0.6297 1.0 1986257 ChemDiv2_005118 CC(NCC(O)Cn1c(C)c(C)c2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I15 compound treatment 0.274 0.0247 1.33 1.3283 1.0 1986258 ChemDiv2_005119 CCOC(=O)N1CCC(CC1)Nc2nc(NCC=C)nc(OCC)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I16 compound treatment 0.535 0.286 15.35 15.3539 1.0 1986259 ChemDiv2_005120 COCc1nc(no1)c2ccc(nc2OC)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I17 compound treatment 0.596 0.347 18.63 18.6319 1.0 1986260 ChemDiv2_005121 COc1ccc(cc1S(=O)(=O)N2CCN(CCO)CC2)c3nnc4c5ccccc5c(C)nn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I18 compound treatment 0.352 0.103 5.52 5.5199 1.0 1272276 ChemDiv2_005122 Cc1nc2sc3c(NCc4ccccc4)ncnc3c2c5CC(C)(C)OCc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I19 compound treatment 0.287 0.0377 2.03 2.0269 1.0 1986261 ChemDiv2_005123 CCc1cc2c(=O)c(coc2c(CN3CCC(C)CC3)c1O)c4nc5ccccc5[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I20 compound treatment 0.487 0.238 12.77 12.7745 1.0 1986262 ChemDiv2_005124 COc1ccc(OC)c(NC(=O)Cn2cc(C(=O)c3ccco3)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I21 compound treatment 0.292 0.0427 2.3 2.2956 1.0 1986263 ChemDiv2_005125 Cc1oc2cc(OCC(=O)O)ccc2c(=O)c1c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I22 compound treatment 0.254 0.00472 0.25 0.2536 1.0 1986264 ChemDiv2_005126 CCC(=O)c1cn(CC(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I23 mock treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 I24 mock treatment 0.252 0.00272 0.15 0.1461 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J01 compound treatment 0.237 -0.0123 -0.66 -0.66 -1.0 1986265 ChemDiv2_005127 Cc1ccccc1NC(=O)CN2C(=O)CSc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J02 compound treatment 0.298 0.0487 2.62 2.618 1.0 1986266 ChemDiv2_005128 Cc1sc2nc(SCc3ccccc3)n(C)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J03 compound treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1986267 ChemDiv2_005129 CC(=O)Nc1ccc(Br)cc1c2nc3ccccc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J04 compound treatment 0.537 0.288 15.46 15.4614 1.0 1986268 ChemDiv2_005130 Nc1nc(CSc2nnc(o2)c3cccc(Br)c3)nc(Nc4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J05 compound treatment 0.563 0.314 16.86 16.8586 1.0 1986269 ChemDiv2_005131 COc1cccc(c1)c2nc(no2)c3cc4ccccc4nc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J06 compound treatment 0.308 0.0587 3.16 3.1554 1.0 1986270 ChemDiv2_005132 CCOC(=O)c1cnn(c1NC(=O)CSc2nc3ccccc3o2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J07 compound treatment 0.459 0.21 11.27 11.2698 1.0 1986271 ChemDiv2_005133 CN(C)S(=O)(=O)c1cccc(c1)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J08 compound treatment 0.507 0.258 13.85 13.8493 1.0 1175480 ChemDiv2_005134 CCCOc1cccc(c1)C(=O)Nc2cccc(c2)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J09 compound treatment 0.358 0.109 5.84 5.8423 1.0 1986272 ChemDiv2_005135 Nc1ncnc2n(Cc3ccccc3)c(SCCC(=O)O)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J10 compound treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1201665 ChemDiv2_005136 Cc1cccc(NC(=O)C2CCCN2C(=O)OCc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J11 compound treatment 0.251 0.00172 0.09 0.0924 1.0 1986273 ChemDiv2_005137 COc1cc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J12 compound treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1196132 ChemDiv2_005138 CCc1c(C)[nH]c2nc(NC(=O)C)nn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J13 compound treatment 0.312 0.0627 3.37 3.3704 1.0 1986274 ChemDiv2_005139 Cc1cc(C)c2c(n1)sc3c(ncnc32)N4CCN(CC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J14 compound treatment 0.287 0.0377 2.03 2.0269 1.0 1532868 ChemDiv2_005140 COc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(C#CC(C)(C)O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J15 compound treatment 0.493 0.244 13.1 13.0969 1.0 1986275 ChemDiv2_005141 CC(C)(C)NC(=O)CSc1nc(ccc1C#N)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J16 compound treatment 0.279 0.0297 1.6 1.597 1.0 1242649 ChemDiv2_005142 COc1ccc(CCNC(=O)c2ccn[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J17 compound treatment 0.521 0.272 14.6 14.6016 1.0 1386814 ChemDiv2_005143 Clc1ccc(OCC(=O)NCC2(OC3C=C2)C4C3C(=O)N(Cc5ccccc5)C4=O)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J18 compound treatment 0.378 0.129 6.92 6.9171 1.0 1274387 ChemDiv2_005144 Cc1ccccc1n2c(CSc3ncccn3)nc4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J19 compound treatment 0.345 0.0957 5.14 5.1437 1.0 1676862 ChemDiv2_005145 O=C(CSc1nsc(SCC(=O)NC2CC2)c1C#N)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J20 compound treatment 0.263 0.0137 0.74 0.7372 1.0 1986276 ChemDiv2_005146 OC(=O)CSc1nc(O)cc(O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J21 compound treatment 0.497 0.248 13.31 13.3119 1.0 1986277 ChemDiv2_005147 O=C(CSC1=NC(=O)CC(=O)N1)Nc2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J22 compound treatment 0.284 0.0347 1.87 1.8657 1.0 1418875 ChemDiv2_005148 COc1ccc(cc1)c2cn3c(nc4n(C)c(=O)n(C)c(=O)c43)n2CCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J23 mock treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 J24 mock treatment 0.241 -0.00828 -0.45 -0.445 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K01 compound treatment 0.241 -0.00828 -0.45 -0.445 -1.0 1352229 ChemDiv2_005149 CC(NC(=O)CSc1nnc2c3ccccc3n(C)c2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K02 compound treatment 0.294 0.0447 2.4 2.4031 1.0 1986278 ChemDiv2_005150 Oc1ccccc1CNc2nc3ccccc3n2CCN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K03 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1940491 ChemDiv2_005151 CCCc1c(O)nc(SCC(=O)O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K04 compound treatment 0.462 0.213 11.43 11.4311 1.0 1986279 ChemDiv2_005152 COc1ccc(OC(C)c2nc(no2)c3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K05 compound treatment 0.268 0.0187 1.01 1.0059 1.0 1986280 ChemDiv2_005153 Cc1nn(c2nnn[nH]2)c3oc(=O)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K06 compound treatment 0.363 0.114 6.11 6.111 1.0 1986281 ChemDiv2_005154 Cc1cc(F)ccc1S(=O)(=O)N(C(=O)c2ccncc2)c3ccc4oc(=O)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K07 compound treatment 0.288 0.0387 2.08 2.0807 1.0 1986282 ChemDiv2_005155 NC(=O)Cn1cc(C(=O)c2cccs2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K08 compound treatment 0.303 0.0537 2.89 2.8867 1.0 1874091 ChemDiv2_005156 O=C(Nc1c(oc2ccccc12)C(=O)c3ccccc3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K09 compound treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1986283 ChemDiv2_005157 CN(C)c1nc(nc(n1)C(=O)O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K10 compound treatment 0.274 0.0247 1.33 1.3283 1.0 1986284 ChemDiv2_005158 COc1ccccc1NC(=O)c2nn(C)c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K11 compound treatment 0.396 0.147 7.88 7.8844 1.0 1986285 ChemDiv2_005159 Cc1nnc2sc(nn12)c3csc4CCCCc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K12 compound treatment 0.306 0.0567 3.05 3.0479 1.0 1986286 ChemDiv2_005160 COCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4cccc(O)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K13 compound treatment 0.433 0.184 9.87 9.8727 1.0 1986287 ChemDiv2_005161 O=C(OCCn1c2ccccc2c3nc4ccccc4nc13)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K14 compound treatment 0.262 0.0127 0.68 0.6835 1.0 1986288 ChemDiv2_005162 CCOC(=O)c1c(C)n(C)c2ccc(OCC(O)CN(CC)CC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K15 compound treatment 0.393 0.144 7.72 7.7231 1.0 1986289 ChemDiv2_005163 CCOC(=O)N1CCC(CC1)Nc2nc(Nc3ccccc3)nc(OC)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K16 compound treatment 0.495 0.246 13.2 13.2044 1.0 1986290 ChemDiv2_005164 CCOc1ccccc1c2nc(no2)c3ccc(nc3OC)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K17 compound treatment 0.379 0.13 6.97 6.9708 1.0 1986291 ChemDiv2_005165 Oc1nc(nc2n(CC3CCCO3)nnc12)C(=O)NCc4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K18 compound treatment 0.359 0.11 5.9 5.8961 1.0 1662363 ChemDiv2_005166 CCCCN(C)c1nc(c2ccco2)c3COC(C)(C)Cc3c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K19 compound treatment 0.329 0.0797 4.28 4.2839 1.0 1986292 ChemDiv2_005167 CCc1cc2c(=O)c(coc2cc1OC(=O)N3CCOCC3)c4nc5ccccc5[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K20 compound treatment 0.321 0.0717 3.85 3.854 1.0 1986293 ChemDiv2_005168 CCN(CC)C(=O)Cn1cc(C(=O)c2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K21 compound treatment 0.368 0.119 6.38 6.3797 1.0 1986294 ChemDiv2_005169 COc1ccc(cc1OC)c2c(C)oc3cc(O)cc(O)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K22 compound treatment 0.291 0.0417 2.24 2.2419 1.0 1986295 ChemDiv2_005170 Cc1ccc(cc1)c2oc3ncnc(N)c3c2c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K23 mock treatment 0.267 0.0177 0.95 0.9522 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 K24 mock treatment 0.259 0.00972 0.52 0.5223 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L01 compound treatment 0.237 -0.0123 -0.66 -0.66 -1.0 1986296 ChemDiv2_005171 CCc1c(O)nc(SCC(=O)NCc2ccco2)n(c3ccccc3)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L02 compound treatment 0.394 0.145 7.78 7.7769 1.0 1132522 ChemDiv2_005172 CCc1nnc(NC(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L03 compound treatment 0.253 0.00372 0.2 0.1998 1.0 1986297 ChemDiv2_005173 Fc1ccccc1N2C(=O)c3ccccc3S2(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L04 compound treatment 0.416 0.167 8.96 8.9591 1.0 1986298 ChemDiv2_005174 OC(=O)c1ccc(CSc2nnc(o2)c3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L05 compound treatment 0.339 0.0897 4.82 4.8213 1.0 1986299 ChemDiv2_005175 O=C1N(c2ccccc2C#N)S(=O)(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L06 compound treatment 0.435 0.186 9.98 9.9801 1.0 1677562 ChemDiv2_005176 CCc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L07 compound treatment 0.483 0.234 12.56 12.5596 1.0 1986300 ChemDiv2_005177 O=S(=O)(N1CCCC1)c2cccc(c2)c3cn4cccnc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L08 compound treatment 0.292 0.0427 2.3 2.2956 1.0 1408158 ChemDiv2_005178 CC(=O)OCCn1nc(c2ccccc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L09 compound treatment 0.271 0.0217 1.17 1.1671 1.0 1986301 ChemDiv2_005179 CC(Sc1nc2c(N)ncnc2n1CCOc3ccccc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L10 compound treatment 0.322 0.0727 3.91 3.9078 1.0 1275136 ChemDiv2_005180 C1CCN(CC1)c2ncnc3c4ccccc4[nH]c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L11 compound treatment 0.287 0.0377 2.03 2.0269 1.0 1986302 ChemDiv2_005181 COc1cc(NC(=O)Cn2c(nc3ccccc23)c4cncs4)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L12 compound treatment 0.25 7.19E-4 0.04 0.0386 1.0 1215821 ChemDiv2_005182 CC(C)Nc1nc(NC2CCCC2)nc(n1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L13 compound treatment 0.529 0.28 15.03 15.0315 1.0 1986303 ChemDiv2_005183 Oc1ccccc1c2nnc(SC3CC(=O)N(C3=O)c4ccc(Br)cc4)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L14 compound treatment 0.27 0.0207 1.11 1.1134 1.0 1950575 ChemDiv2_005184 COC(=O)C1=CNC=C(C1c2ccc(cc2)C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L15 compound treatment 0.249 -2.81E-4 -0.02 -0.0151 -1.0 1371 ChemDiv2_005185 CN(C)c1nc(nc(n1)N(C)C)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L16 compound treatment 0.239 -0.0103 -0.55 -0.5525 -1.0 1658727 ChemDiv2_005186 OCCNC(=O)c1ccn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L17 compound treatment 0.275 0.0257 1.38 1.3821 1.0 1344037 ChemDiv2_005187 O=C(Nc1nc[nH]n1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L18 compound treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1686654 ChemDiv2_005188 CN(C(=O)CSc1nc2ccccc2c(=O)n1Cc3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L19 compound treatment 0.451 0.202 10.84 10.8399 1.0 1986304 ChemDiv2_005189 O=C(CSc1nsc(SCC(=O)Nc2ccccc2)c1C#N)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L20 compound treatment 0.248 -0.00128 -0.07 -0.0689 -1.0 1986305 ChemDiv2_005190 Cn1c(=O)n(C)c2ncn(CCCNC3=CC(=O)CC(C)(C)C3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L21 compound treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1718689 ChemDiv2_005191 CSc1c(CC(=O)NC(C)(C)CO)n(Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L22 compound treatment 0.236 -0.0133 -0.71 -0.7137 -1.0 1254550 ChemDiv2_005192 Cn1c(=O)n(C)c2nc3n(c(cn3c2c1=O)c4cccs4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L23 mock treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 L24 mock treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M01 compound treatment 0.268 0.0187 1.01 1.0059 1.0 1536635 ChemDiv2_005193 CC(NC(=O)CSc1nnc2c3ccccc3n(CC=C)c2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M02 compound treatment 0.287 0.0377 2.03 2.0269 1.0 1986306 ChemDiv2_005194 CSc1nnc-2c(OC3(Nc4ccccc42)C(=O)Nc5ccc(Cl)cc53)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M03 compound treatment 0.288 0.0387 2.08 2.0807 1.0 1986307 ChemDiv2_005195 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)NCCc3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M04 compound treatment 0.341 0.0917 4.93 4.9288 1.0 1986308 ChemDiv2_005196 CCOC(=O)CSc1nc(C)cc(Oc2ccc(=O)n(C)n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M05 compound treatment 0.24 -0.00928 -0.5 -0.4988 -1.0 1986309 ChemDiv2_005197 NC(=O)Cn1cc(C(=O)C2CC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M06 compound treatment 0.306 0.0567 3.05 3.0479 1.0 1986310 ChemDiv2_005198 CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CSc4nnc(C)s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M07 compound treatment 0.265 0.0157 0.84 0.8447 1.0 1986311 ChemDiv2_005199 O=C(Cn1cc(C(=O)c2cccs2)c3ccccc13)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M08 compound treatment 0.364 0.115 6.16 6.1647 1.0 1986312 ChemDiv2_005200 CC(=O)Nc1ccc2n3CCN(Cc4ccccc4)Cc3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M09 compound treatment 0.381 0.132 7.08 7.0783 1.0 1986313 ChemDiv2_005201 CC(c1ccccc1)n2c(nc3ccccc23)C4CN(C(=O)C4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M10 compound treatment 0.378 0.129 6.92 6.9171 1.0 1986314 ChemDiv2_005202 CC(=O)Nc1ccc(cc1)c2nnc3c4ccccc4c(C)nn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M11 compound treatment 0.302 0.0527 2.83 2.833 1.0 1986315 ChemDiv2_005203 Clc1ccc(cc1)c2noc(CCC(=O)OCc3ccc(Br)cc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M12 compound treatment 0.304 0.0547 2.94 2.9405 1.0 1986316 ChemDiv2_005204 Cc1ccc(cc1)C2N(C(=O)c3oc4ccc(C)cc4c(=O)c23)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M13 compound treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1986317 ChemDiv2_005205 CC(=O)Nc1nc2CCCCCc2c3c4ccccc4oc(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M14 compound treatment 0.268 0.0187 1.01 1.0059 1.0 1986318 ChemDiv2_005206 CCOC(=O)c1c(C)n(C)c2ccc(OCC(O)CNC3CCCCC3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M15 compound treatment 0.326 0.0767 4.12 4.1227 1.0 1986319 ChemDiv2_005207 CCCN(CCC)c1nc(NC2CCN(CC2)C(=O)OCC)nc(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M16 compound treatment 0.366 0.117 6.27 6.2722 1.0 1986320 ChemDiv2_005208 COc1nc(ccc1c2noc(COc3ccccc3)n2)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M17 compound treatment 0.454 0.205 11.0 11.0012 1.0 1986321 ChemDiv2_005209 Cc1ccc(Cn2nnc3c(O)nc(nc23)C4CCN(CC4)C(=O)CC(C)(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M18 compound treatment 0.332 0.0827 4.45 4.4451 1.0 1986322 ChemDiv2_005210 CC(C1SC(=O)NC1=O)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M19 compound treatment 0.284 0.0347 1.87 1.8657 1.0 1986323 ChemDiv2_005211 CN(C)C(=O)Oc1ccc2c(=O)c(c3nc4ccccc4s3)c(C)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M20 compound treatment 0.507 0.258 13.85 13.8493 1.0 1986324 ChemDiv2_005212 CCn1c(SCc2nc(no2)c3ccc(Cl)cc3)nnc1c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M21 compound treatment 0.261 0.0117 0.63 0.6297 1.0 1986325 ChemDiv2_005213 Cc1cccc(OCC(O)Cn2c(=N)n(C)c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M22 compound treatment 0.257 0.00772 0.41 0.4148 1.0 1986326 ChemDiv2_005214 Oc1ccc(cc1)C2N(Cc3ccccc3)C(=O)c4oc5ccccc5c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M23 mock treatment 0.251 0.00172 0.09 0.0924 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 M24 mock treatment 0.251 0.00172 0.09 0.0924 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N01 compound treatment 0.257 0.00772 0.41 0.4148 1.0 1986327 ChemDiv2_005215 Oc1ccccc1N2C(=O)CC(C2=O)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N02 compound treatment 0.36 0.111 5.95 5.9498 1.0 1986328 ChemDiv2_005216 O=C(CSc1nc(cc(n1)c2ccccc2)c3ccccc3)NC4=NC(=O)CS4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N03 compound treatment 0.479 0.23 12.34 12.3446 1.0 1986329 ChemDiv2_005217 CCc1nc(no1)c2cc3ccc(C)cc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N04 compound treatment 0.266 0.0167 0.9 0.8984 1.0 1687088 ChemDiv2_005218 Cc1csc(NC(=O)C2CCCN2C(=O)Oc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N05 compound treatment 0.317 0.0677 3.64 3.6391 1.0 1986330 ChemDiv2_005219 COc1ccc(cc1OC)c2cc(C(=O)NC(Cc3c[nH]c4ccccc34)C(=O)O)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N06 compound treatment 0.379 0.13 6.97 6.9708 1.0 1986331 ChemDiv2_005220 CC(Sc1nnnn1c2ccccc2)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N07 compound treatment 0.504 0.255 13.69 13.6881 1.0 1986332 ChemDiv2_005221 CCN(CC)S(=O)(=O)c1cccc(c1)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N08 compound treatment 0.294 0.0447 2.4 2.4031 1.0 1986333 ChemDiv2_005222 CC(=O)OCCn1nc(C)c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N09 compound treatment 0.273 0.0237 1.27 1.2746 1.0 1986334 ChemDiv2_005223 CCOc1ccc(OCCn2c(SCC(=O)O)nc3c(N)ncnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N10 compound treatment 0.29 0.0407 2.19 2.1881 1.0 1986335 ChemDiv2_005224 CCc1c(C#N)c(SC)nc(C)c1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N11 compound treatment 0.329 0.0797 4.28 4.2839 1.0 1986336 ChemDiv2_005225 O=c1[nH]c2ccc(cc2[nH]1)S(=O)(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N12 compound treatment 0.424 0.175 9.39 9.389 1.0 1267936 ChemDiv2_005226 Cc1cc(C)nc(Nc2ccccc2C(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N13 compound treatment 0.333 0.0837 4.5 4.4989 1.0 1986337 ChemDiv2_005227 CCOC(=O)C(C)Sc1nc(C)cc(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N14 compound treatment 0.33 0.0807 4.34 4.3377 1.0 1986338 ChemDiv2_005228 COc1ccc(OCCSc2nc(C)nc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N15 compound treatment 0.258 0.00872 0.47 0.4685 1.0 1986339 ChemDiv2_005229 CCC(CC)NC1=NS(=O)(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N16 compound treatment 0.241 -0.00828 -0.45 -0.445 -1.0 1986340 ChemDiv2_005230 Nc1nc(CCl)nc(n1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N17 compound treatment 0.307 0.0577 3.1 3.1017 1.0 1004303 ChemDiv2_005231 CCOC(=O)C1=C(C)NC(=C(C1)C(=O)OCC)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N18 compound treatment 0.247 -0.00228 -0.12 -0.1226 -1.0 1313127 ChemDiv2_005232 CCCOc1ccc(cc1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N19 compound treatment 0.25 7.19E-4 0.04 0.0386 1.0 1436646 ChemDiv2_005233 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N20 compound treatment 0.293 0.0437 2.35 2.3494 1.0 1697330 ChemDiv2_005234 COc1ccc(cc1)N2C(=O)CC(N(Cc3ccc4OCOc4c3)C(=O)c5cccc(F)c5)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N21 compound treatment 0.305 0.0557 2.99 2.9942 1.0 1348208 ChemDiv2_005235 OCCCn1c(csc1=Nc2ccccc2)c3ccc(cc3)S(=O)(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N22 compound treatment 0.239 -0.0103 -0.55 -0.5525 -1.0 1469339 ChemDiv2_005236 COc1ccccc1OCCn2c(=O)c3cc4c(=O)n(CCOc5ccccc5OC)c(=O)c4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N23 mock treatment 0.241 -0.00828 -0.45 -0.445 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 N24 mock treatment 0.238 -0.0113 -0.61 -0.6062 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O01 compound treatment 0.241 -0.00828 -0.45 -0.445 -1.0 1660770 ChemDiv2_005237 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)NC(C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O02 compound treatment 0.317 0.0677 3.64 3.6391 1.0 1986341 ChemDiv2_005238 CCOC(=O)c1ccc(NCc2nc3ccccc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O03 compound treatment 0.252 0.00272 0.15 0.1461 1.0 1986342 ChemDiv2_005239 CN(C)S(=O)(=O)N(CC(=O)Nc1ccccc1F)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O04 compound treatment 0.32 0.0707 3.8 3.8003 1.0 1986343 ChemDiv2_005240 O=C(CSc1nc[nH]n1)Nc2nc(ns2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O05 compound treatment 0.255 0.00572 0.31 0.3073 1.0 1986344 ChemDiv2_005241 O=C(Cn1cc(C(=O)C2CC2)c3ccccc13)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O06 compound treatment 0.551 0.302 16.21 16.2137 1.0 1986345 ChemDiv2_005242 Cc1nnc(SCc2cc(=O)[nH]c(Nc3nc(C)c4cc(C)ccc4n3)n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O07 compound treatment 0.391 0.142 7.62 7.6157 1.0 1986346 ChemDiv2_005243 CCOC(=O)Cn1cc(C(=O)c2cccs2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O08 compound treatment 0.536 0.287 15.41 15.4077 1.0 1986347 ChemDiv2_005244 O=C(Nc1ccc2n3CCN(Cc4ccccc4)Cc3nc2c1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O09 compound treatment 0.485 0.236 12.67 12.667 1.0 1986348 ChemDiv2_005245 O=C(Nc1nc2CCCNC(=O)c2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O10 compound treatment 0.257 0.00772 0.41 0.4148 1.0 1986349 ChemDiv2_005246 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O11 compound treatment 0.294 0.0447 2.4 2.4031 1.0 1986350 ChemDiv2_005247 Clc1ccc(cc1)C2N(C(=O)c3oc4ccccc4c(=O)c23)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O12 compound treatment 0.275 0.0257 1.38 1.3821 1.0 1986351 ChemDiv2_005248 Cc1ccc2nsnc2c1S(=O)(=O)N3CCN=C3Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O13 compound treatment 0.298 0.0487 2.62 2.618 1.0 1986352 ChemDiv2_005249 COc1ccc(Br)c2Cc3sc(NC(=O)C)nc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O14 compound treatment 0.334 0.0847 4.55 4.5526 1.0 1986353 ChemDiv2_005250 CCOC(=O)c1c(C)n(C)c2ccc(OCC(O)CNCc3ccccc3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O15 compound treatment 0.432 0.183 9.82 9.8189 1.0 1986354 ChemDiv2_005251 Cc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O16 compound treatment 0.272 0.0227 1.22 1.2209 1.0 1986355 ChemDiv2_005252 CCOc1nc(C)ccc1c2noc(n2)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O17 compound treatment 0.329 0.0797 4.28 4.2839 1.0 1986356 ChemDiv2_005253 Cc1ccc(C)c(c1)C(=O)N2CCC(CC2)c3nc(O)c4nnn(Cc5ccc(F)cc5F)c4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O18 compound treatment 0.265 0.0157 0.84 0.8447 1.0 1986357 ChemDiv2_005254 O=C(Cn1cc(C(=O)C2CCCCC2)c3ccccc13)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O19 compound treatment 0.264 0.0147 0.79 0.791 1.0 1986358 ChemDiv2_005255 COc1ccc(cc1OC)c2c(C)oc3cc(OC(C)C(=O)O)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O20 compound treatment 0.324 0.0747 4.02 4.0152 1.0 1986359 ChemDiv2_005256 Cn1c(SCc2nc(no2)c3ccccc3)nnc1C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O21 compound treatment 0.257 0.00772 0.41 0.4148 1.0 1986360 ChemDiv2_005257 CCn1c(=N)n(CC(O)COc2cccc(C)c2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O22 compound treatment 0.26 0.0107 0.58 0.576 1.0 1986361 ChemDiv2_005258 Nc1nncn1C(=O)CC2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O23 mock treatment 0.252 0.00272 0.15 0.1461 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 O24 mock treatment 0.257 0.00772 0.41 0.4148 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P01 compound treatment 0.314 0.0647 3.48 3.4779 1.0 1986362 ChemDiv2_005259 CC(C)(C)c1ccc(cc1)c2nnc3sc(nn23)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P02 compound treatment 0.231 -0.0183 -0.98 -0.9824 -1.0 1536535 ChemDiv2_005260 CCC(Sc1nccn1C)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P03 compound treatment 0.28 0.0307 1.65 1.6508 1.0 1986363 ChemDiv2_005261 Cc1ccc2cc(c3noc(n3)C4CCCCC4)c(O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P04 compound treatment 0.223 -0.0263 -1.41 -1.4123 -1.0 1340219 ChemDiv2_005262 CSc1nc2ccccc2n1CC(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P05 compound treatment 0.232 -0.0173 -0.93 -0.9287 -1.0 1986364 ChemDiv2_005263 Cc1onc(c1C(=O)N2CCCCC2C(=O)O)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P06 compound treatment 0.234 -0.0153 -0.82 -0.8212 -1.0 1726854 ChemDiv2_005264 Cn1nccc1C(=O)Nc2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P07 compound treatment 0.295 0.0457 2.46 2.4568 1.0 1986365 ChemDiv2_005265 CC1CN(CC(C)O1)S(=O)(=O)c2cccc(c2)c3cn4cccnc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P08 compound treatment 0.228 -0.0213 -1.14 -1.1436 -1.0 1231527 ChemDiv2_005266 O=C1N(C(=O)c2cccc3cccc1c23)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P09 compound treatment 0.388 0.139 7.45 7.4545 1.0 1986366 ChemDiv2_005267 COc1ccc(OCCn2c(nc3ccccc23)S(=O)(=O)Cc4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P10 compound treatment 0.256 0.00672 0.36 0.3611 1.0 1947300 ChemDiv2_005268 CC(=O)n1c(SCC(=O)Nc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P11 compound treatment 0.263 0.0137 0.74 0.7372 1.0 1986367 ChemDiv2_005269 OC(=O)c1ccc(cc1)S(=O)(=O)Nc2ccc3oc4CCCCc4c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P12 compound treatment 0.226 -0.0233 -1.25 -1.2511 -1.0 1254995 ChemDiv2_005270 CCSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P13 compound treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1986368 ChemDiv2_005271 CCOC(=O)C1=C(N)OC2=C(C1c3cccs3)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P14 compound treatment 0.23 -0.0193 -1.04 -1.0361 -1.0 1163747 ChemDiv2_005272 CC(C)Nc1nc(nc(n1)N2CCCC2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P15 compound treatment 0.369 0.12 6.43 6.4334 1.0 1421331 ChemDiv2_005273 Cc1ccc(cc1)S(=O)(=O)NCc2nnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P16 compound treatment 0.234 -0.0153 -0.82 -0.8212 -1.0 1556306 ChemDiv2_005274 Cc1c(CCN)c2ccccc2n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P17 compound treatment 0.24 -0.00928 -0.5 -0.4988 -1.0 1519587 ChemDiv2_005275 Brc1ccc(cc1)C(=O)CN2C(=O)C3(OCCO3)c4cc(Br)ccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P18 compound treatment 0.235 -0.0143 -0.77 -0.7674 -1.0 1986369 ChemDiv2_005276 CC(=O)Nc1c(C)cc(C)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P19 compound treatment 0.244 -0.00528 -0.28 -0.2838 -1.0 1986370 ChemDiv2_005277 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P20 compound treatment 0.324 0.0747 4.02 4.0152 1.0 1986371 ChemDiv2_005278 Cc1cccc(NC(=O)C2CC(=O)N/C(=N/c3ccccc3)/S2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P21 compound treatment 0.243 -0.00628 -0.34 -0.3375 -1.0 1158630 ChemDiv2_005279 Nc1nc(CSc2nc3ccccc3s2)nc(n1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P22 compound treatment 0.24 -0.00928 -0.5 -0.4988 -1.0 1154569 ChemDiv2_005280 CCCn1c2ccccc2c3nnc(SCC(=O)NC4CCCC4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P23 mock treatment 0.242 -0.00728 -0.39 -0.3913 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1383 P24 mock treatment 0.245 -0.00428 -0.23 -0.2301 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A01 compound treatment 0.21 -0.0368 -1.98 -1.9782 -1.0 1380752 ChemDiv2_005281 Nc1nc(CSc2nnc(c3cccc(F)c3)n2c4ccccc4)nc(n1)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A02 compound treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1986372 ChemDiv2_005282 CCOC(=O)Cc1nnc(NC(=O)C(CC)Sc2nc(C)cc(C)n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A03 compound treatment 0.229 -0.0178 -0.96 -0.9572 -1.0 1491012 ChemDiv2_005283 CCCn1c(cn2c1nc3n(C)c(=O)n(C)c(=O)c32)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A04 compound treatment 0.23 -0.0168 -0.9 -0.9035 -1.0 1986373 ChemDiv2_005284 Cc1ccc2n3CCN(C4CCCc(c43)c2c1)C(=O)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A05 compound treatment 0.222 -0.0248 -1.33 -1.3334 -1.0 1986374 ChemDiv2_005285 CN(C)CCCSc1nc(C)cc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A06 compound treatment 0.215 -0.0318 -1.71 -1.7095 -1.0 1986375 ChemDiv2_005286 CCOc1cc(NC(=O)c2ccnn2C)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A07 compound treatment 0.218 -0.0288 -1.55 -1.5483 -1.0 1288369 ChemDiv2_005287 Cc1cccc(c1)N2CCn3c2nc4n(C)c(=O)n(C)c(=O)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A08 compound treatment 0.22 -0.0268 -1.44 -1.4408 -1.0 1986376 ChemDiv2_005288 COc1ccc2[nH]c(C)c(CCN3CCC(=O)C(C)C3C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A09 compound treatment 0.262 0.0152 0.82 0.8161 1.0 1214626 ChemDiv2_005289 Cc1nc2nc(nn2c(C)c1C)S(=O)(=O)N(CC=C)CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A10 compound treatment 0.233 -0.0138 -0.74 -0.7423 -1.0 1986377 ChemDiv2_005290 CC(Sc1nc(=O)cc(N)n1CCc2ccccc2)C(=O)Nc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A11 compound treatment 0.227 -0.0198 -1.06 -1.0647 -1.0 1478967 ChemDiv2_005291 Cc1cc(C)c(C#N)c(Oc2cccc(N)c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A12 compound treatment 0.215 -0.0318 -1.71 -1.7095 -1.0 1986378 ChemDiv2_005292 CCN1CCN(CC1)c2ncnc3n(c4ccccc4)c(=S)sc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A13 compound treatment 0.234 -0.0128 -0.69 -0.6885 -1.0 1986379 ChemDiv2_005293 CN(C1CCS(=O)(=O)C1)S(=O)(=O)c2cccc3N=S=Nc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A14 compound treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1986380 ChemDiv2_005294 Cc1nc2ccccc2nc1CSc3nnc(o3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A15 compound treatment 0.247 1.88E-4 0.01 0.0101 1.0 1986381 ChemDiv2_005295 Cn1nccc1C(=O)Nc2ccc(CC#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A16 compound treatment 0.25 0.00319 0.17 0.1713 1.0 1986382 ChemDiv2_005296 CC(Sc1nc(C)c(Cl)c(C)c1C#N)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A17 compound treatment 0.396 0.149 8.02 8.017 1.0 1986383 ChemDiv2_005297 COc1ccc2[nH]c(C)c(CCNCc3ccc(C#N)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A18 compound treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1986384 ChemDiv2_005298 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A19 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1986385 ChemDiv2_005299 Clc1ccc(CNc2nc(Cl)nc(NCCN3CCOCC3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A20 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1986386 ChemDiv2_005300 CCOc1cc(NC(=O)c2ccc(OC)c(c2)S(=O)(=O)N3CCC(C)CC3)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A21 compound treatment 0.269 0.0222 1.19 1.1923 1.0 1986387 ChemDiv2_005301 COc1cccc2cc(C(=O)N3CCC(C)CC3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A22 compound treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1986388 ChemDiv2_005302 Clc1ccc(cc1)c2nnc(SCc3nc(no3)c4ccccc4)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A23 mock treatment 0.267 0.0202 1.08 1.0848 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 A24 mock treatment 0.27 0.0232 1.25 1.246 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B01 compound treatment 0.227 -0.0198 -1.06 -1.0647 -1.0 1986389 ChemDiv2_005303 CN(C)c1nc(C)nc2n(C)c(=S)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B02 compound treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1986390 ChemDiv2_005304 COc1cc(NC(=O)CCc2nc(no2)C3=CCN(C)CC3)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B03 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1986391 ChemDiv2_005305 N/C(=N/O)/c1nc(nc(n1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B04 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1317010 ChemDiv2_005306 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nnc(o3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B05 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1986392 ChemDiv2_005307 COc1cccc(NC(=O)CCCN2C(=O)C3C4CC(C=C4)C3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B06 compound treatment 0.251 0.00419 0.23 0.225 1.0 1986393 ChemDiv2_005308 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)NCC4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B07 compound treatment 0.233 -0.0138 -0.74 -0.7423 -1.0 1140300 ChemDiv2_005309 O=C(N(Cc1ccccc1)c2ccccc2)c3cnc4SCCn4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B08 compound treatment 0.484 0.237 12.75 12.746 1.0 1986394 ChemDiv2_005310 CCOC(=O)C1CCN(CC1)c2cc(NCC(=O)O)c3C(=O)c4ccccc4-c5onc2c53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B09 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986395 ChemDiv2_005311 O=C(NCc1ccco1)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B10 compound treatment 0.278 0.0312 1.68 1.676 1.0 1986396 ChemDiv2_005312 Cc1sc2ncn(CC(=O)NCCC3=CCCCC3)c(=O)c2c1S(=O)(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B11 compound treatment 0.351 0.104 5.6 5.5988 1.0 1986397 ChemDiv2_005313 COc1ccc(cc1Cl)n2nc(C(=O)NCC(=O)Nc3ccc4OCCOc4c3)c5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B12 compound treatment 0.238 -0.00881 -0.47 -0.4736 -1.0 1986398 ChemDiv2_005314 COc1ccc(cc1)C2C(C(=O)Nc3ccc4OCCOc4c3)c5ccccc5C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B13 compound treatment 0.267 0.0202 1.08 1.0848 1.0 1986399 ChemDiv2_005315 CC1CCN(CC1)S(=O)(=O)c2ccc3ncn(CC(=O)Nc4cnc5ccccc5c4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B14 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1339592 ChemDiv2_005316 CCc1ccc(Nc2nnc(Cc3ccc(OC)cc3)c(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B15 compound treatment 0.226 -0.0208 -1.12 -1.1184 -1.0 1560951 ChemDiv2_005317 CCOC(=O)c1sc2ncn(CC(=O)N)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B16 compound treatment 0.289 0.0422 2.27 2.2671 1.0 1986400 ChemDiv2_005318 CCc1cccc(NC(=O)CCS(=O)(=O)c2cccc3nonc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B17 compound treatment 0.308 0.0612 3.29 3.2881 1.0 1986401 ChemDiv2_005319 O=C(NCCCN1CCCCCC1)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B18 compound treatment 0.267 0.0202 1.08 1.0848 1.0 1986402 ChemDiv2_005320 CN(C(=O)CN1C(=O)c2ccccc2S1(=O)=O)c3ccccc3C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B19 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1986403 ChemDiv2_005321 Cc1ccccc1NC(=O)C2C3N(CCc4ccccc34)C(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B20 compound treatment 0.27 0.0232 1.25 1.246 1.0 1986404 ChemDiv2_005322 CCN/C(=C/c1nsc(Nc2ccc(Cl)cc2)n1)/C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B21 compound treatment 0.359 0.112 6.03 6.0287 1.0 1986405 ChemDiv2_005323 COc1ccc(cc1)c2noc(n2)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B22 compound treatment 0.256 0.00919 0.49 0.4937 1.0 1986406 ChemDiv2_005324 CCN(CC)c1cc(C)c2cc(NC(=O)c3ccco3)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B23 mock treatment 0.236 -0.0108 -0.58 -0.581 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 B24 mock treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C01 compound treatment 0.353 0.106 5.71 5.7063 1.0 1986407 ChemDiv2_005325 Clc1cc2OCOc2cc1CSc3nnc(c4cccnc4)n3CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C02 compound treatment 0.375 0.128 6.89 6.8885 1.0 1986408 ChemDiv2_005326 Cc1ncsc1CCSc2nc3ccccc3c(=O)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C03 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986409 ChemDiv2_005327 CCOC(=O)c1[nH]c(C)c(C2C(=C(N)OC3=C2C(=O)CCC3)C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C04 compound treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1986410 ChemDiv2_005328 Cn1nnnc1SCC(=O)Nc2nn(nc2C(=O)N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C05 compound treatment 0.266 0.0192 1.03 1.0311 1.0 1541624 ChemDiv2_005329 CCOc1nc(C#N)nc(n1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C06 compound treatment 0.348 0.101 5.44 5.4376 1.0 1986411 ChemDiv2_005330 Cc1cc(C)nc(n1)N(Cc2ccccc2Cl)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C07 compound treatment 0.275 0.0282 1.51 1.5147 1.0 1368018 ChemDiv2_005331 O=C(CN1C(=O)c2ccccc2C1=O)OC3CSCC3NC(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C08 compound treatment 0.25 0.00319 0.17 0.1713 1.0 1986412 ChemDiv2_005332 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4coc5ccccc5c4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C09 compound treatment 0.235 -0.0118 -0.63 -0.6348 -1.0 1986413 ChemDiv2_005333 CCOc1ccc(CCNC(=O)CSc2nc(C)c(Cl)c(C)c2C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C10 compound treatment 0.246 -8.12E-4 -0.04 -0.0437 -1.0 1986414 ChemDiv2_005334 COc1ccc(CCNC(=O)COc2nsnc2N3CCOCC3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C11 compound treatment 0.439 0.192 10.33 10.3278 1.0 1348996 ChemDiv2_005335 Cc1cc(NC(=O)c2sc(Nc3ccccc3)c(C#N)c2N)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C12 compound treatment 0.264 0.0172 0.92 0.9236 1.0 1986415 ChemDiv2_005336 COc1ccc(CCNC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4F)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C13 compound treatment 0.326 0.0792 4.26 4.2554 1.0 1285231 ChemDiv2_005337 O=C(CCCN1C(=O)c2ccccc2C1=O)N3c4ccccc4Sc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C14 compound treatment 0.441 0.194 10.44 10.4352 1.0 1986416 ChemDiv2_005338 CCN(Cc1ccccc1)C(=O)CSc2nc3nc(C)cc(C)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C15 compound treatment 0.401 0.154 8.29 8.2857 1.0 1986417 ChemDiv2_005339 C=CCn1c(SCc2ccc3nonc3c2)nnc1c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C16 compound treatment 0.246 -8.12E-4 -0.04 -0.0437 -1.0 1986418 ChemDiv2_005340 CN(C(=O)CSc1ncn[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C17 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986419 ChemDiv2_005341 CCOc1ccc(cc1OC)C2Nc3ccccc3C(C)(C)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C18 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986420 ChemDiv2_005342 CN(C(=O)CSc1nc(N)nn1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C19 compound treatment 0.264 0.0172 0.92 0.9236 1.0 1986421 ChemDiv2_005343 CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCc3ccc(cc3)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C20 compound treatment 0.446 0.199 10.7 10.7039 1.0 1986422 ChemDiv2_005344 O=C(Nc1nnc(s1)C2CC2)c3cccc(c3)S(=O)(=O)N4CC(CC4=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C21 compound treatment 0.361 0.114 6.14 6.1362 1.0 1986423 ChemDiv2_005345 Cc1cc(C)nc(SCC2=NC(C)(C)Cc3ccccc23)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C22 compound treatment 0.258 0.0112 0.6 0.6012 1.0 1986424 ChemDiv2_005346 CN(C1CCS(=O)(=O)C1)C(=O)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C23 mock treatment 0.254 0.00719 0.39 0.3862 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 C24 mock treatment 0.25 0.00319 0.17 0.1713 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D01 compound treatment 0.247 1.88E-4 0.01 0.0101 1.0 1986425 ChemDiv2_005347 CCN1CCN(CC1)c2nc(C)nc3n(C)c(=S)sc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D02 compound treatment 0.226 -0.0208 -1.12 -1.1184 -1.0 1986426 ChemDiv2_005348 Cn1c(C(=O)O)c(CC(=O)N2CCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D03 compound treatment 0.237 -0.00981 -0.53 -0.5273 -1.0 1986427 ChemDiv2_005349 CN(C)c1nc(nc(n1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D04 compound treatment 0.374 0.127 6.83 6.8348 1.0 1986428 ChemDiv2_005350 O=C(Nc1nnc(o1)C2CC2)c3ccc(cc3)S(=O)(=O)N4CCCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D05 compound treatment 0.283 0.0362 1.94 1.9446 1.0 1492927 ChemDiv2_005351 O=C(CCCN1C(=O)C2C3CC(C=C3)C2C1=O)N4CCN(CC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D06 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1986429 ChemDiv2_005352 CCOc1ccc(cc1)N(CC)C(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D07 compound treatment 0.249 0.00219 0.12 0.1176 1.0 1668118 ChemDiv2_005353 O=c1n(c2ccc3OCOc3c2)c(=O)c4ccccc4c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D08 compound treatment 0.248 0.00119 0.06 0.0638 1.0 1986430 ChemDiv2_005354 CCN1CCN(CC1)c2cc(NCC(=O)O)c3C(=O)c4ccccc4-c5onc2c53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D09 compound treatment 0.318 0.0712 3.83 3.8255 1.0 1986431 ChemDiv2_005355 COc1ccc(c(OC)c1)n2nc(C(=O)NCC(=O)Nc3ccc4OCOc4c3)c5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D10 compound treatment 0.263 0.0162 0.87 0.8699 1.0 1231904 ChemDiv2_005356 Cc1sc2ncn(CC(=O)Nc3ccc(Oc4ccccc4)cc3)c(=O)c2c1S(=O)(=O)N5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D11 compound treatment 0.232 -0.0148 -0.8 -0.796 -1.0 1986432 ChemDiv2_005357 COc1ccc(cc1)C2C(C(=O)Nc3ccccn3)c4ccccc4C(=O)N2C5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D12 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986433 ChemDiv2_005358 COc1ccc(cc1)C2C(C(=O)N3CCN(CC3)c4ccccc4)c5ccccc5C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D13 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1986434 ChemDiv2_005359 Cc1cc(nc2ccc(cc12)N3C(=O)CCC3=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D14 compound treatment 0.32 0.0732 3.93 3.9329 1.0 1214604 ChemDiv2_005360 COc1ccc(Cc2nnc(Nc3ccc4OCOc4c3)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D15 compound treatment 0.381 0.134 7.21 7.211 1.0 1986435 ChemDiv2_005361 CCOC(=O)c1sc2ncn(CC(=O)N3CCCc4ccccc34)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D16 compound treatment 0.258 0.0112 0.6 0.6012 1.0 1986436 ChemDiv2_005362 CC1CCCCC1NC(=O)CCS(=O)(=O)c2cccc3nonc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D17 compound treatment 0.492 0.245 13.18 13.1759 1.0 1986437 ChemDiv2_005363 CCCN(CCC)C(=O)c1cc2c(=O)oc3ccccc3c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D18 compound treatment 0.49 0.243 13.07 13.0684 1.0 1986438 ChemDiv2_005364 Cc1ccc(cc1)N(Cc2ccccc2O)C(=O)CN3C(=O)c4ccccc4S3(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D19 compound treatment 0.286 0.0392 2.11 2.1059 1.0 1986439 ChemDiv2_005365 CCOc1ccc(cc1)c2noc(CCC(=O)O)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D20 compound treatment 0.266 0.0192 1.03 1.0311 1.0 1986440 ChemDiv2_005366 O=C(NCCc1ccccc1)C2C3OC4(CN(Cc5cccs5)C(=O)C24)C=C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D21 compound treatment 0.377 0.13 7.0 6.996 1.0 1986441 ChemDiv2_005367 COc1ccc(cc1)c2noc(Nc3cc(OC)ccc3OC)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D22 compound treatment 0.25 0.00319 0.17 0.1713 1.0 1986442 ChemDiv2_005368 CCN(CC)c1cc(C)c2cc(NC(=O)C3CC3)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D23 mock treatment 0.238 -0.00881 -0.47 -0.4736 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 D24 mock treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E01 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1715424 ChemDiv2_005369 CC(C)(C)NC(=O)CSc1nnc2c3ccccc3n(CC=C)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E02 compound treatment 0.234 -0.0128 -0.69 -0.6885 -1.0 1986443 ChemDiv2_005370 CNc1nc(Cl)nc(Oc2ccc(=O)n(C)n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E03 compound treatment 0.275 0.0282 1.51 1.5147 1.0 1569564 ChemDiv2_005371 NC(=O)c1noc(C(=O)c2ccccc2)c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E04 compound treatment 0.227 -0.0198 -1.06 -1.0647 -1.0 1986444 ChemDiv2_005372 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3c(oc4ccccc34)C(=O)C5CC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E05 compound treatment 0.221 -0.0258 -1.39 -1.3871 -1.0 1986445 ChemDiv2_005373 CC(C)C1Cc2c(CO1)sc3c2c(=O)n(c4ccccc4)c5nncn53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E06 compound treatment 0.373 0.126 6.78 6.7811 1.0 1986446 ChemDiv2_005374 CCOC(=O)Cc1nnc(NC(=O)C(CC)Sc2nc3ccccc3[nH]2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E07 compound treatment 0.398 0.151 8.12 8.1245 1.0 1165432 ChemDiv2_005375 Cc1ccc(cc1)c2noc(CN(Cc3ccco3)S(=O)(=O)C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E08 compound treatment 0.286 0.0392 2.11 2.1059 1.0 1986447 ChemDiv2_005376 CCSc1nc2cc(ccc2c(=O)n1CC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E09 compound treatment 0.298 0.0512 2.75 2.7507 1.0 1425027 ChemDiv2_005377 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)c3nn(CC(=O)NCc4ccccn4)c(=O)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E10 compound treatment 0.339 0.0922 4.95 4.954 1.0 1986448 ChemDiv2_005378 Cc1cc(C)c(C#N)c(SCC(=O)NC(C)(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E11 compound treatment 0.4 0.153 8.23 8.232 1.0 1334019 ChemDiv2_005379 C=CCN(C(=O)COc1ccccc1)c2nnc(s2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E12 compound treatment 0.296 0.0492 2.64 2.6432 1.0 1986449 ChemDiv2_005380 N#Cc1nc(nc(n1)N2CCCC2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E13 compound treatment 0.411 0.164 8.82 8.8231 1.0 1986450 ChemDiv2_005381 CCCn1c2ccccc2c3nnc(SCC(=O)Nc4ccc(F)c(F)c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E14 compound treatment 0.492 0.245 13.18 13.1759 1.0 1986451 ChemDiv2_005382 Cc1cc(C)n2nc(SCC(=O)N(c3ccccc3)c4ccccc4)nc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E15 compound treatment 0.246 -8.12E-4 -0.04 -0.0437 -1.0 1986452 ChemDiv2_005383 COC(=O)C(C1CCCC1)C(=O)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E16 compound treatment 0.247 1.88E-4 0.01 0.0101 1.0 1986453 ChemDiv2_005384 Cc1cc(C)c2c(n1)sc3c(=O)n(nnc32)c4cccc5cccnc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E17 compound treatment 0.349 0.102 5.49 5.4913 1.0 1986454 ChemDiv2_005385 CN(C)S(=O)(=O)c1cc(C(=O)NCCc2ccccc2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E18 compound treatment 0.265 0.0182 0.98 0.9774 1.0 1986455 ChemDiv2_005386 CCCCN(C#N)c1nc(nc(n1)N2CCOCC2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E19 compound treatment 0.43 0.183 9.84 9.8441 1.0 1986456 ChemDiv2_005387 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CSc3nnc4c5ccccc5n(CC=C)c4n3)cc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E20 compound treatment 0.465 0.218 11.72 11.7249 1.0 1986457 ChemDiv2_005388 Cc1nnc(NC(=O)c2cccc(c2)S(=O)(=O)N3CC(CC3=O)c4ccccc4)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E21 compound treatment 0.395 0.148 7.96 7.9633 1.0 1986458 ChemDiv2_005389 O=C(CC1CCS(=O)(=O)C1)Nc2ccc[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E22 compound treatment 0.259 0.0122 0.65 0.6549 1.0 1986459 ChemDiv2_005390 CCCN(CC1CC1)S(=O)(=O)c2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E23 mock treatment 0.257 0.0102 0.55 0.5475 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 E24 mock treatment 0.255 0.00819 0.44 0.44 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F01 compound treatment 0.236 -0.0108 -0.58 -0.581 -1.0 1986460 ChemDiv2_005391 CN(C)c1cc(C)nc(Nc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F02 compound treatment 0.283 0.0362 1.94 1.9446 1.0 1986461 ChemDiv2_005392 Cn1c(C(=O)O)c(CC(=O)NCC2COc3ccccc3O2)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F03 compound treatment 0.263 0.0162 0.87 0.8699 1.0 1986462 ChemDiv2_005393 C=CCN(C#N)c1nc(nc(n1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F04 compound treatment 0.377 0.13 7.0 6.996 1.0 1986463 ChemDiv2_005394 CSCc1nnc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F05 compound treatment 0.25 0.00319 0.17 0.1713 1.0 1986464 ChemDiv2_005395 COc1ccc(OC)c(NC(=O)c2coc(=O)c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F06 compound treatment 0.257 0.0102 0.55 0.5475 1.0 1986465 ChemDiv2_005396 COc1ccc(cc1)N(C)C(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F07 compound treatment 0.249 0.00219 0.12 0.1176 1.0 1986466 ChemDiv2_005397 CN(C(=O)Cc1c(C(=O)O)n(C)c2ccccc12)c3ccc(C)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F08 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986467 ChemDiv2_005398 CCN1CCN(CC1)c2ncc(C(=O)Nc3ccccc3C(=O)OC)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F09 compound treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1986468 ChemDiv2_005399 CC(C)NC(=O)c1n[nH]c(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F10 compound treatment 0.233 -0.0138 -0.74 -0.7423 -1.0 1986469 ChemDiv2_005400 COCCN1C(C(C(=O)NCc2ccccn2)c3ccccc3C1=O)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F11 compound treatment 0.23 -0.0168 -0.9 -0.9035 -1.0 1986470 ChemDiv2_005401 CCOc1ccc(cc1)C2C(C(=O)O)c3ccccc3C(=O)N2CCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F12 compound treatment 0.254 0.00719 0.39 0.3862 1.0 1986471 ChemDiv2_005402 COc1ccc(cc1)C2C(C(=O)N3CCC4(CC3)OCCO4)c5ccccc5C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F13 compound treatment 0.237 -0.00981 -0.53 -0.5273 -1.0 1986472 ChemDiv2_005403 CCN(C(=O)c1coc(=O)c2ccccc12)c3ccccc3CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F14 compound treatment 0.447 0.2 10.76 10.7577 1.0 1296968 ChemDiv2_005404 Cc1nnc(Nc2ccc3OCCOc3c2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F15 compound treatment 0.281 0.0342 1.84 1.8372 1.0 1986473 ChemDiv2_005405 Cc1ccc(CNC(=O)c2coc(=O)c3ccccc23)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F16 compound treatment 0.351 0.104 5.6 5.5988 1.0 1986474 ChemDiv2_005406 CC1Cc2ccccc2N1C(=O)CCS(=O)(=O)c3cccc4nonc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F17 compound treatment 0.299 0.0522 2.8 2.8044 1.0 1986475 ChemDiv2_005407 O=C(Nc1cccc(C#N)c1)c2coc(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F18 compound treatment 0.504 0.257 13.82 13.8207 1.0 1986476 ChemDiv2_005408 COc1cc(CN(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)c4ccc(Cl)cc4)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F19 compound treatment 0.251 0.00419 0.23 0.225 1.0 1986477 ChemDiv2_005409 O=C(C1C2CCCCN2C(=O)c3ccccc13)N4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F20 compound treatment 0.23 -0.0168 -0.9 -0.9035 -1.0 1986478 ChemDiv2_005410 CN1CCN(CCCNC(=O)C2C3OC4(CN(Cc5ccccc5Cl)C(=O)C24)C=C3)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F21 compound treatment 0.446 0.199 10.7 10.7039 1.0 1986479 ChemDiv2_005411 O=C(Nc1ccc2nc3CCCCCn3c(=O)c2c1)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F22 compound treatment 0.454 0.207 11.13 11.1338 1.0 1986480 ChemDiv2_005412 CCc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F23 mock treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 F24 mock treatment 0.229 -0.0178 -0.96 -0.9572 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G01 compound treatment 0.303 0.0562 3.02 3.0194 1.0 1986481 ChemDiv2_005413 CCC(=O)Nc1nc2nc(cc(O)n2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G02 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986482 ChemDiv2_005414 COc1nc(OCC#N)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G03 compound treatment 0.251 0.00419 0.23 0.225 1.0 1136133 ChemDiv2_005415 CCn1c(SCC(=O)NC2CCCCC2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G04 compound treatment 0.279 0.0322 1.73 1.7297 1.0 1986483 ChemDiv2_005416 Fc1ccc(cc1)n2c(SCc3cc(=O)[nH]c4ccccc34)nc5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G05 compound treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1986484 ChemDiv2_005417 CCOC(=O)Cc1nc2[nH]c(C)c(Br)c(=O)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G06 compound treatment 0.322 0.0752 4.04 4.0404 1.0 1986485 ChemDiv2_005418 COc1cc(Br)cc2cc(C(=O)NCc3ccc4OCOc4c3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G07 compound treatment 0.232 -0.0148 -0.8 -0.796 -1.0 1410875 ChemDiv2_005419 CCC(=O)Nc1nc(nc2c3ccccc3oc(=O)c12)c4ccc(Cl)c(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G08 compound treatment 0.517 0.27 14.52 14.5193 1.0 1986486 ChemDiv2_005420 CCOC(=O)Nc1ccc2n(cnc2c1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G09 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1197538 ChemDiv2_005421 CC1(C)CC(CC(C)(C)N1)NC(=O)Cn2nc(c3ccccc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G10 compound treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1986487 ChemDiv2_005422 CN1CCC(CC1)OC(=O)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G11 compound treatment 0.259 0.0122 0.65 0.6549 1.0 1530659 ChemDiv2_005423 O=C1C2C3CC(C=C3)C2C(=O)N1c4sc5CCCc5c4C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G12 compound treatment 0.293 0.0462 2.48 2.482 1.0 1986488 ChemDiv2_005424 C=CCOc1nc(nc(n1)N2CCCC2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G13 compound treatment 0.231 -0.0158 -0.85 -0.8497 -1.0 1986489 ChemDiv2_005425 Cc1ccc(C#N)c(SC(C)(C)C(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G14 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1986490 ChemDiv2_005426 COCc1cc(C)nc2sc3c(=O)n(Cc4ccco4)nnc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G15 compound treatment 0.282 0.0352 1.89 1.8909 1.0 1986491 ChemDiv2_005427 COC(=O)C1Cc2c([nH]c3ccccc23)C(N1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G16 compound treatment 0.516 0.269 14.47 14.4656 1.0 1986492 ChemDiv2_005428 Cc1cc(C)c(C#N)c(SCC(=O)N(Cc2ccccc2)Cc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G17 compound treatment 0.273 0.0262 1.41 1.4073 1.0 1986493 ChemDiv2_005429 COc1nc(OC/C(=N/O)/N)nc(n1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G18 compound treatment 0.272 0.0252 1.35 1.3535 1.0 1986494 ChemDiv2_005430 CCCN(CCC)S(=O)(=O)c1nc2nc(C)cc(C)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G19 compound treatment 0.533 0.286 15.38 15.3791 1.0 1986495 ChemDiv2_005431 CCc1c(C)nc(SCCOc2ccc(OC)cc2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G20 compound treatment 0.448 0.201 10.81 10.8114 1.0 1986496 ChemDiv2_005432 COc1ccc(cc1S(=O)(=O)N2CC(CC2=O)c3ccccc3)C(=O)Nc4nncs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G21 compound treatment 0.271 0.0242 1.3 1.2998 1.0 1986497 ChemDiv2_005433 CCCCc1cc2c3ccccc3oc(=O)c2c(NC(=O)CC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G22 compound treatment 0.503 0.256 13.77 13.767 1.0 1986498 ChemDiv2_005434 COc1ccc2oc(COc3ccccc3)c(C(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G23 mock treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 G24 mock treatment 0.248 0.00119 0.06 0.0638 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H01 compound treatment 0.299 0.0522 2.8 2.8044 1.0 1986499 ChemDiv2_005435 Cc1nn(Cc2nc(no2)c3cccs3)c(C)c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H02 compound treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1986500 ChemDiv2_005436 CC1CCN(CCCNC(=O)Cc2c(C(=O)O)n(C)c3ccccc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H03 compound treatment 0.269 0.0222 1.19 1.1923 1.0 1986501 ChemDiv2_005437 CN(c1ccccc1)S(=O)(=O)c2nc(C)c(Cl)c(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H04 compound treatment 0.491 0.244 13.12 13.1221 1.0 1986502 ChemDiv2_005438 Cc1cc(NC(=O)CCCN2C(=O)c3cccnc3C2=O)ccc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H05 compound treatment 0.25 0.00319 0.17 0.1713 1.0 1986503 ChemDiv2_005439 CCCCN(C)C(=O)c1coc(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H06 compound treatment 0.256 0.00919 0.49 0.4937 1.0 1986504 ChemDiv2_005440 CC(C)CN(CC(C)C)C(=O)Cn1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H07 compound treatment 0.411 0.164 8.82 8.8231 1.0 1334980 ChemDiv2_005441 O=C(Nc1ccc(Oc2ccccc2)cc1)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H08 compound treatment 0.235 -0.0118 -0.63 -0.6348 -1.0 1986505 ChemDiv2_005442 CN(C(C(=O)Nc1c(C)cccc1C)c2ccccc2)C(=O)c3cnccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H09 compound treatment 0.362 0.115 6.19 6.1899 1.0 1986506 ChemDiv2_005443 O=C(NCC1COc2ccccc2O1)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H10 compound treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1986507 ChemDiv2_005444 COCCN1C(C(C(=O)NCCCN2CCCC2)c3ccccc3C1=O)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H11 compound treatment 0.256 0.00919 0.49 0.4937 1.0 1986508 ChemDiv2_005445 CCOc1ccc(NC(=O)CNC(=O)c2nn(c3ccc(OC)c(OC)c3)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H12 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986509 ChemDiv2_005446 COC(=O)CNC(=O)C1C(N(Cc2ccc(F)cc2)C(=O)c3ccccc13)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H13 compound treatment 0.323 0.0762 4.09 4.0942 1.0 1986510 ChemDiv2_005447 CCOc1ccc(CCNC(=O)c2coc(=O)c3ccccc23)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H14 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986511 ChemDiv2_005448 Cc1ccc2[nH]c3CCN(Cc4ccccc4)Cc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H15 compound treatment 0.302 0.0552 2.97 2.9657 1.0 1986512 ChemDiv2_005449 CCOc1sc2nc(C)n(CC(=O)N(CC)CC)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H16 compound treatment 0.452 0.205 11.03 11.0263 1.0 1986513 ChemDiv2_005450 CCOC(=O)c1cccc(NC(=O)CCS(=O)(=O)c2cccc3nsnc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H17 compound treatment 0.354 0.107 5.76 5.76 1.0 1986514 ChemDiv2_005451 O=C(Nc1cccnc1)c2coc(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H18 compound treatment 0.282 0.0352 1.89 1.8909 1.0 1453547 ChemDiv2_005452 O=C1CCCC2=C1C(c3ccncc3)c4c(N2)nc(SCc5ccccc5)[nH]c4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H19 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986515 ChemDiv2_005453 CC(C)NC(=O)Cn1ncc2c(=O)oc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H20 compound treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1986516 ChemDiv2_005454 COc1ccc(cc1)N2C(C(CCC2=O)C(=O)NC(C)C)c3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H21 compound treatment 0.324 0.0772 4.15 4.1479 1.0 1986517 ChemDiv2_005455 CC(C)NC(=O)c1ccc2c(=O)n3CCCCCc3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H22 compound treatment 0.463 0.216 11.62 11.6175 1.0 1986518 ChemDiv2_005456 COc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)N4CCN(CC4)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H23 mock treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 H24 mock treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I01 compound treatment 0.226 -0.0208 -1.12 -1.1184 -1.0 1578065 ChemDiv2_005457 Cn1c(SCc2nc(N)nc(n2)N3CCCCC3)nc4n(C)c(=O)n(C)c(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I02 compound treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1986519 ChemDiv2_005458 Nc1nc(C#N)nc(n1)N(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I03 compound treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1986520 ChemDiv2_005459 OC(=O)CCCNc1nc(F)cc(F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I04 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1986521 ChemDiv2_005460 ClC1=CCC2C(C1)C(=O)N(C2=O)c3nnc[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I05 compound treatment 0.266 0.0192 1.03 1.0311 1.0 1341076 ChemDiv2_005461 CCOc1ccc(CCNC(=O)CN2C(=O)c3ccccc3C2=O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I06 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986522 ChemDiv2_005462 CCOc1ccc(Cn2c(O)nc3n(C)c(=O)n(C)c(=O)c23)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I07 compound treatment 0.336 0.0892 4.79 4.7927 1.0 1385203 ChemDiv2_005463 Cn1c(N)c(sc1=S)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I08 compound treatment 0.553 0.306 16.45 16.4539 1.0 1986523 ChemDiv2_005464 O=C(Nc1ccc2OCCOc2c1)c3nc[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I09 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986524 ChemDiv2_005465 Cc1nc2nc(SCC(=O)O)nn2c(C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I10 compound treatment 0.304 0.0572 3.07 3.0731 1.0 1986525 ChemDiv2_005466 COc1ccc(cc1S(=O)(=O)Nc2ccccc2)C(=O)Nc3ccon3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I11 compound treatment 0.425 0.178 9.58 9.5754 1.0 1409003 ChemDiv2_005467 CC(C)n1c2ccccc2c3nnc(SCc4ccc5nonc5c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I12 compound treatment 0.246 -8.12E-4 -0.04 -0.0437 -1.0 1986526 ChemDiv2_005468 COc1nc(Oc2nc(OC)nc(n2)N3CCCC3)nc(n1)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I13 compound treatment 0.408 0.161 8.66 8.6619 1.0 1986527 ChemDiv2_005469 CC(C)n1c2ccccc2c3nnc(SCC(=O)NCc4ccc5OCOc5c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I14 compound treatment 0.384 0.137 7.37 7.3722 1.0 1986528 ChemDiv2_005470 CN(C)S(=O)(=O)c1cc(C(=O)Nc2nccs2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I15 compound treatment 0.474 0.227 12.21 12.2086 1.0 1986529 ChemDiv2_005471 CCCn1c2ccccc2c3nnc(SCC(=O)Nc4ccc5OCCOc5c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I16 compound treatment 0.279 0.0322 1.73 1.7297 1.0 1986530 ChemDiv2_005472 COc1ccc(NS(=O)(=O)Cc2ccccc2Cl)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I17 compound treatment 0.578 0.331 17.8 17.7973 1.0 1986531 ChemDiv2_005473 CCOc1nc(nc(n1)n2cc(nn2)c3ccccc3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I18 compound treatment 0.287 0.0402 2.16 2.1596 1.0 1986532 ChemDiv2_005474 COc1ccc(cc1)n2nnc3c(sc4nc(C)cc(C)c43)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I19 compound treatment 0.285 0.0382 2.05 2.0521 1.0 1986533 ChemDiv2_005475 c1cn(cn1)c2nc(nc(n2)n3ccnc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I20 compound treatment 0.363 0.116 6.24 6.2437 1.0 1986534 ChemDiv2_005476 COc1ccc(cc1S(=O)(=O)N2CC(CC2=O)c3ccccc3)C(=O)Nc4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I21 compound treatment 0.416 0.169 9.09 9.0918 1.0 1986535 ChemDiv2_005477 Cn1c(SCc2ccon2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I22 compound treatment 0.26 0.0132 0.71 0.7087 1.0 1736822 ChemDiv2_005478 Cc1csc(NC(=O)C2CCC(C)(C(=O)O)C2(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I23 mock treatment 0.25 0.00319 0.17 0.1713 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 I24 mock treatment 0.256 0.00919 0.49 0.4937 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J01 compound treatment 0.333 0.0862 4.63 4.6315 1.0 1986536 ChemDiv2_005479 c1csc(c1)c2noc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J02 compound treatment 0.259 0.0122 0.65 0.6549 1.0 1986537 ChemDiv2_005480 COc1ccc(cc1)n2nc(C(=O)NCC(=O)NCc3ccccn3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J03 compound treatment 0.274 0.0272 1.46 1.461 1.0 1986538 ChemDiv2_005481 Cc1nc(c(C#N)c(C)c1Cl)S(=O)(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J04 compound treatment 0.463 0.216 11.62 11.6175 1.0 1986539 ChemDiv2_005482 O=C(CCS(=O)(=O)c1ccc2[nH]c(=O)oc2c1)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J05 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986540 ChemDiv2_005483 CC1CC(C)CN(C1)C(=O)c2coc(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J06 compound treatment 0.251 0.00419 0.23 0.225 1.0 1986541 ChemDiv2_005484 CC1Cc2ccccc2N1C(=O)Cn3c(=O)oc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J07 compound treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1986542 ChemDiv2_005485 COc1ccc(c(OC)c1)n2nc(C(=O)NCC(=O)NC3CCCC(C)C3C)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J08 compound treatment 0.257 0.0102 0.55 0.5475 1.0 1986543 ChemDiv2_005486 COc1ccc(NC(=O)C(N(C)C(=O)c2ccc(=O)[nH]c2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J09 compound treatment 0.374 0.127 6.83 6.8348 1.0 1986544 ChemDiv2_005487 O=C(Nc1nc2ccccc2s1)c3n[nH]c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J10 compound treatment 0.259 0.0122 0.65 0.6549 1.0 1986545 ChemDiv2_005488 CCOc1ccc(cc1)C2C(C(=O)Nc3ccc(F)cc3)c4ccccc4C(=O)N2CCN5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J11 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986546 ChemDiv2_005489 COc1ccc(cc1)C2C(C(=O)NCCCN3CCOCC3)c4ccccc4C(=O)N2c5ccc(OC)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J12 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986547 ChemDiv2_005490 COc1ccc(cc1)C2C(C(=O)NCCCN3CCN(C)CC3)c4ccccc4C(=O)N2Cc5ccc(F)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J13 compound treatment 0.254 0.00719 0.39 0.3862 1.0 1986548 ChemDiv2_005491 COc1ccc(C)cc1N(C)C(=O)c2coc(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J14 compound treatment 0.259 0.0122 0.65 0.6549 1.0 1986549 ChemDiv2_005492 O=C(CCS(=O)(=O)c1cccc2nonc12)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J15 compound treatment 0.344 0.0972 5.22 5.2227 1.0 1986550 ChemDiv2_005493 CN1CCN(CCCNC(=O)c2cnc(Nc3ccc(C)c(Cl)c3)c4ccccc24)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J16 compound treatment 0.306 0.0592 3.18 3.1806 1.0 1986551 ChemDiv2_005494 O=C(CCS(=O)(=O)c1cccc2nsnc12)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J17 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986552 ChemDiv2_005495 O=C(NC1CC1)C2C3N(CCc4ccccc34)C(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J18 compound treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1127689 ChemDiv2_005496 CSc1nc2NC3=C(C(c4ccccc4)c2c(=O)[nH]1)C(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J19 compound treatment 0.448 0.201 10.81 10.8114 1.0 1986553 ChemDiv2_005497 Cc1ccc2[nH]c(=O)c3cc(sc3c2c1)C(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J20 compound treatment 0.295 0.0482 2.59 2.5895 1.0 1986554 ChemDiv2_005498 COc1ccc(cc1)N2C(C(CCC2=O)C(=O)NCc3ccc(F)cc3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J21 compound treatment 0.275 0.0282 1.51 1.5147 1.0 1986555 ChemDiv2_005499 CCOC(=O)n1nc(Cc2ccncc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J22 compound treatment 0.357 0.11 5.92 5.9212 1.0 1986556 ChemDiv2_005500 CCOc1ccc(CCNC(=O)C2COc3ccccc3O2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J23 mock treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 J24 mock treatment 0.246 -8.12E-4 -0.04 -0.0437 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K01 compound treatment 0.227 -0.0198 -1.06 -1.0647 -1.0 1146908 ChemDiv2_005501 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(N4CCOCC4)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K02 compound treatment 0.234 -0.0128 -0.69 -0.6885 -1.0 1374421 ChemDiv2_005502 CCOC(=O)CNc1nc(Cl)nc(n1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K03 compound treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1986557 ChemDiv2_005503 OC(=O)CNC1=NC2(CCCCC2)Cc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K04 compound treatment 0.247 1.88E-4 0.01 0.0101 1.0 1619285 ChemDiv2_005504 CN(C1CCCCC1)C(=O)c2cc3cc(Br)ccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K05 compound treatment 0.229 -0.0178 -0.96 -0.9572 -1.0 1986558 ChemDiv2_005505 OC(=O)CCC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccc(O)cc4O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K06 compound treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1986559 ChemDiv2_005506 COc1cc(OC)nc(NC(=O)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K07 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1361186 ChemDiv2_005507 CC(C)N1CC(CC1=O)C(=O)Nc2cccc(Cl)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K08 compound treatment 0.479 0.232 12.48 12.4773 1.0 1986560 ChemDiv2_005508 CCc1nnc(s1)N2C(=O)c3ccccc3C2(O)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K09 compound treatment 0.251 0.00419 0.23 0.225 1.0 1986561 ChemDiv2_005509 CCCCc1nc(CNCCc2c(C)[nH]c3ccc(OC)cc23)c[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K10 compound treatment 0.264 0.0172 0.92 0.9236 1.0 1986562 ChemDiv2_005510 Nc1cc(=O)nc(SCC(=O)NCc2ccccc2)n1CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K11 compound treatment 0.271 0.0242 1.3 1.2998 1.0 1986563 ChemDiv2_005511 CC(C)(C)/C(=C/C1=Nc2ccccc2SC1(O)CC(=O)C(C)(C)C)/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K12 compound treatment 0.401 0.154 8.29 8.2857 1.0 1986564 ChemDiv2_005512 CCOC(=O)C1C(CC(=CC1=O)Nc2ccccc2F)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K13 compound treatment 0.275 0.0282 1.51 1.5147 1.0 1986565 ChemDiv2_005513 Clc1cnc(Oc2ccc(OC(=O)c3ccco3)cc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K14 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986566 ChemDiv2_005514 CN(C)c1nc(N)nc(CSc2nnnn2c3ccc4OCOc4c3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K15 compound treatment 0.279 0.0322 1.73 1.7297 1.0 1986567 ChemDiv2_005515 COCc1cc(C)nc(OCC(=O)OC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K16 compound treatment 0.276 0.0292 1.57 1.5685 1.0 1986568 ChemDiv2_005516 Nc1nc(SCC(=O)N2CCCc3ccccc23)n(n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K17 compound treatment 0.325 0.0782 4.2 4.2016 1.0 1986569 ChemDiv2_005517 CCN(CC)c1nc(C#N)nc(n1)N(CC)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K18 compound treatment 0.282 0.0352 1.89 1.8909 1.0 1986570 ChemDiv2_005518 CCC(Sc1nc(=O)cc(N)n1CCc2ccccc2)C(=O)Nc3ccccc3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K19 compound treatment 0.267 0.0202 1.08 1.0848 1.0 1986571 ChemDiv2_005519 CCc1c(nc2nc(C)c(C)nn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K20 compound treatment 0.396 0.149 8.02 8.017 1.0 1986572 ChemDiv2_005520 CC(C)C(=O)N1CCN(CC1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K21 compound treatment 0.279 0.0322 1.73 1.7297 1.0 1986573 ChemDiv2_005521 Cc1cc(C)c(C#N)c(Nc2ccc3OCCOc3c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K22 compound treatment 0.256 0.00919 0.49 0.4937 1.0 1986574 ChemDiv2_005522 CC(C)N1C(=O)C2C(NC(C)(C2C1=O)C(=O)O)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K23 mock treatment 0.251 0.00419 0.23 0.225 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 K24 mock treatment 0.258 0.0112 0.6 0.6012 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L01 compound treatment 0.364 0.117 6.3 6.2974 1.0 1986575 ChemDiv2_005523 COC(=O)c1ccc(cc1)c2nc(no2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L02 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986576 ChemDiv2_005524 COc1ccc(cc1)n2nc(C(=O)NCC(=O)N3CCCCC3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L03 compound treatment 0.25 0.00319 0.17 0.1713 1.0 1722739 ChemDiv2_005525 O=C(NC1CCCCC1)c2ccc3c(=O)n(Cc4ccccc4)c(SCC#N)nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L04 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986577 ChemDiv2_005526 Clc1ccccc1CCNC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L05 compound treatment 0.247 1.88E-4 0.01 0.0101 1.0 1189327 ChemDiv2_005527 COc1ccc(cc1)C2C3=C(CCCC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L06 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986578 ChemDiv2_005528 CCCN(C(=O)Cn1c(=O)oc2ccccc12)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L07 compound treatment 0.257 0.0102 0.55 0.5475 1.0 1986579 ChemDiv2_005529 COc1ccc(c(OC)c1)n2nc(C(=O)NCC(=O)NCC3CCCO3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L08 compound treatment 0.275 0.0282 1.51 1.5147 1.0 1986580 ChemDiv2_005530 COc1ccc(NC(=O)C(N(C)C(=O)c2cnccn2)c3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L09 compound treatment 0.271 0.0242 1.3 1.2998 1.0 1986581 ChemDiv2_005531 CC1CCN(CCCNC(=O)c2n[nH]c(=O)c3ccccc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L10 compound treatment 0.257 0.0102 0.55 0.5475 1.0 1986582 ChemDiv2_005532 CCOc1ccc(cc1)C2C(C(=O)Nc3ccccn3)c4ccccc4C(=O)N2CCN5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L11 compound treatment 0.267 0.0202 1.08 1.0848 1.0 1986583 ChemDiv2_005533 COc1ccc(cc1)C2C(CCC(=O)N2c3ccc(OC)cc3)C(=O)Nc4cccc(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L12 compound treatment 0.255 0.00819 0.44 0.44 1.0 1679360 ChemDiv2_005534 CCOC(=O)c1c(NC(=O)C(C)Sc2nc3n(ncc3c(=O)[nH]2)c4ccc(F)cc4)sc5CCCc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L13 compound treatment 0.248 0.00119 0.06 0.0638 1.0 1986584 ChemDiv2_005535 CCc1ccc(cc1)C2C(C(=O)O)c3ccccc3C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L14 compound treatment 0.319 0.0722 3.88 3.8792 1.0 1986585 ChemDiv2_005536 Clc1cccc(NC(=O)CCS(=O)(=O)c2cccc3nonc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L15 compound treatment 0.321 0.0742 3.99 3.9867 1.0 1986586 ChemDiv2_005537 CCN(Cc1ccccc1)C(=O)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L16 compound treatment 0.437 0.19 10.22 10.2203 1.0 1986587 ChemDiv2_005538 CCc1ccc(NC(=O)CNS(=O)(=O)c2cccc3nonc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L17 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986588 ChemDiv2_005539 CN1C(C(C(=O)O)c2ccccc2C1=O)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L18 compound treatment 0.31 0.0632 3.4 3.3956 1.0 1689679 ChemDiv2_005540 COC(=O)C1=C(C)Nc2nc(SC)[nH]c(=O)c2C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L19 compound treatment 0.342 0.0952 5.12 5.1152 1.0 1986589 ChemDiv2_005541 COc1ccc2cc3c(N)nn(C(=O)Cc4ccc(Cl)cc4)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L20 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986590 ChemDiv2_005542 CCOC(=O)N1CCN(CC1)C(=O)C2CCC(=O)N(C2c3ccc(F)cc3)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L21 compound treatment 0.449 0.202 10.87 10.8651 1.0 1986591 ChemDiv2_005543 O=C(NCCC1=CCCCC1)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L22 compound treatment 0.26 0.0132 0.71 0.7087 1.0 1986592 ChemDiv2_005544 CCOc1ccc(OCC)c(NC(=O)C2Cc3ccccc3CN2S(=O)(=O)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L23 mock treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 L24 mock treatment 0.24 -0.00681 -0.37 -0.3661 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M01 compound treatment 0.331 0.0842 4.52 4.5241 1.0 1614133 ChemDiv2_005545 COc1ccc(cc1OC)C(=O)NCCc2c(C)[nH]c3c(C)ccc(F)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M02 compound treatment 0.311 0.0642 3.45 3.4493 1.0 1986593 ChemDiv2_005546 Cc1[nH]c2ccc(C)cc2c1CCNS(=O)(=O)c3ccc4N(CCc4c3)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M03 compound treatment 0.246 -8.12E-4 -0.04 -0.0437 -1.0 1986594 ChemDiv2_005547 CC(C)(C)c1nnc2sc(SCC(=O)Nc3ccc(Br)cc3)nn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M04 compound treatment 0.265 0.0182 0.98 0.9774 1.0 1986595 ChemDiv2_005548 OCCN1CCN(CC1)C(=O)c2cc3c(ccc4ccccc43)oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M05 compound treatment 0.445 0.198 10.65 10.6502 1.0 1455970 ChemDiv2_005549 Nc1c(sc2nc3CCCc3cc12)c4nc(N)nc(n4)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M06 compound treatment 0.274 0.0272 1.46 1.461 1.0 1986596 ChemDiv2_005550 Cc1nc(CN2CCN(CC2)C(=O)c3ccc(cc3)C(C)(C)C)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M07 compound treatment 0.27 0.0232 1.25 1.246 1.0 1986597 ChemDiv2_005551 COc1ccc2[nH]c(C)c(CCNCC(C)Cc3ccc4OCOc4c3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M08 compound treatment 0.241 -0.00581 -0.31 -0.3124 -1.0 1986598 ChemDiv2_005552 O=C(COc1nsnc1N2CCOCC2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M09 compound treatment 0.238 -0.00881 -0.47 -0.4736 -1.0 1986599 ChemDiv2_005553 CC(=O)n1cc(N2C(=O)C3C4CC(C=C4)C3C2=O)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M10 compound treatment 0.446 0.199 10.7 10.7039 1.0 1986600 ChemDiv2_005554 CCc1ccc(cc1)c2cn3nc(C)c(C)nc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M11 compound treatment 0.27 0.0232 1.25 1.246 1.0 1606354 ChemDiv2_005555 O=C(OCc1ccc2nonc2c1)c3c4CCCc4nc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M12 compound treatment 0.282 0.0352 1.89 1.8909 1.0 1986601 ChemDiv2_005556 CCOC(=O)C1C(CC(=CC1=O)Nc2ccc(Br)cn2)c3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M13 compound treatment 0.27 0.0232 1.25 1.246 1.0 1868539 ChemDiv2_005557 Cc1nnc([nH]c1=O)n2nc(cc2N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M14 compound treatment 0.248 0.00119 0.06 0.0638 1.0 1986602 ChemDiv2_005558 COC(=O)c1ccc(Oc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M15 compound treatment 0.254 0.00719 0.39 0.3862 1.0 1986603 ChemDiv2_005559 COc1cc(C)c(C(=O)O)c(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M16 compound treatment 0.322 0.0752 4.04 4.0404 1.0 1986604 ChemDiv2_005560 CCc1nnc(NC(=O)C2CCCN2S(=O)(=O)c3ccccc3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M17 compound treatment 0.27 0.0232 1.25 1.246 1.0 1986605 ChemDiv2_005561 Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c32)n1c4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M18 compound treatment 0.268 0.0212 1.14 1.1386 1.0 1986606 ChemDiv2_005562 COc1nc(nc(n1)n2ccnc2)N(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M19 compound treatment 0.262 0.0152 0.82 0.8161 1.0 1986607 ChemDiv2_005563 Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c32)n1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M20 compound treatment 0.469 0.222 11.94 11.9399 1.0 1986608 ChemDiv2_005564 Cc1cc(NC(=O)c2sc(Nc3ccccc3F)nc2N)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M21 compound treatment 0.269 0.0222 1.19 1.1923 1.0 1986609 ChemDiv2_005565 Clc1nc(NCc2ccco2)nc(n1)N3CC4CC(C3)C5=CC=CC(=O)C5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M22 compound treatment 0.258 0.0112 0.6 0.6012 1.0 1986610 ChemDiv2_005566 CCCC1(NC(C2C1C(=O)N(Cc3ccccc3)C2=O)c4ccccc4O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M23 mock treatment 0.253 0.00619 0.33 0.3325 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 M24 mock treatment 0.247 1.88E-4 0.01 0.0101 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N01 compound treatment 0.23 -0.0168 -0.9 -0.9035 -1.0 1986611 ChemDiv2_005567 CCOC(=O)c1c(CN2CCCCC2C)n(C)c3cc(Br)c(OC(=O)C)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N02 compound treatment 0.262 0.0152 0.82 0.8161 1.0 1393972 ChemDiv2_005568 COc1ccc(cc1)c2nnc(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N03 compound treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1635250 ChemDiv2_005569 CCN(CC)C(=O)c1ccc2c(=O)n(Cc3ccccc3)c(SCC(=O)C(C)(C)C)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N04 compound treatment 0.43 0.183 9.84 9.8441 1.0 1986612 ChemDiv2_005570 Cc1ccc2nc(NC(=O)CN3C(=O)C4C5CC(C=C5)C4C3=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N05 compound treatment 0.327 0.0802 4.31 4.3091 1.0 1273011 ChemDiv2_005571 O=C(NC1CCCC1)c2cnc3SCCn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N06 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1125149 ChemDiv2_005572 CC1CN(CC(C)O1)S(=O)(=O)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N07 compound treatment 0.26 0.0132 0.71 0.7087 1.0 1986613 ChemDiv2_005573 COc1ccc(c(OC)c1)n2nc(C(=O)NCC(=O)NC3CCCCCC3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N08 compound treatment 0.254 0.00719 0.39 0.3862 1.0 1986614 ChemDiv2_005574 CCC(C)(N(C(=O)Cc1cccs1)c2c(C)n(C)n(c3ccccc3)c2=O)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N09 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986615 ChemDiv2_005575 O=C(NCCN1CCCC1)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N10 compound treatment 0.293 0.0462 2.48 2.482 1.0 1986616 ChemDiv2_005576 COc1ccc(cc1)C2C(C(=O)Nc3ccccn3)c4ccccc4C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N11 compound treatment 0.234 -0.0128 -0.69 -0.6885 -1.0 1986617 ChemDiv2_005577 COc1ccc(cc1)C2C(CCC(=O)N2c3ccc(OC)cc3)C(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N12 compound treatment 0.255 0.00819 0.44 0.44 1.0 1290285 ChemDiv2_005578 Cn1c(=O)n(C)c2nc(N3CCCC3)n(CCSc4nc5ccccc5s4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N13 compound treatment 0.44 0.193 10.38 10.3815 1.0 1986618 ChemDiv2_005579 COc1ccc(CNC(=O)c2coc(=O)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N14 compound treatment 0.269 0.0222 1.19 1.1923 1.0 1986619 ChemDiv2_005580 O=C(CCS(=O)(=O)c1cccc2nonc12)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N15 compound treatment 0.263 0.0162 0.87 0.8699 1.0 1986620 ChemDiv2_005581 CCOC(=O)N1CCC(CC1)NC(=O)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N16 compound treatment 0.251 0.00419 0.23 0.225 1.0 1986621 ChemDiv2_005582 O=S(=O)(NCc1cccnc1)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N17 compound treatment 0.263 0.0162 0.87 0.8699 1.0 1986622 ChemDiv2_005583 OC(=O)c1[nH]c2ccc(Cl)cc2c1CC(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N18 compound treatment 0.302 0.0552 2.97 2.9657 1.0 1986623 ChemDiv2_005584 CCOC(=O)C1=C(C)NC2=C(C1c3cccc(OC)c3OC)C(=O)C(C(C)C2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N19 compound treatment 0.254 0.00719 0.39 0.3862 1.0 1986624 ChemDiv2_005585 COc1ccc(NC(=O)c2ccc3c(c4CCCCc4nc3c2)n5ccnc5)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N20 compound treatment 0.234 -0.0128 -0.69 -0.6885 -1.0 1986625 ChemDiv2_005586 CCN1CCCC1CNC(=O)C2C(N(C)C(=O)c3cc(OC)c(OC)cc23)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N21 compound treatment 0.279 0.0322 1.73 1.7297 1.0 1986626 ChemDiv2_005587 COc1cc(NC(=O)c2ccc3c(=O)n4CCCCCc4nc3c2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N22 compound treatment 0.517 0.27 14.52 14.5193 1.0 1986627 ChemDiv2_005588 CCOC(=O)N1CCC(CC1)NC(=O)CCS(=O)(=O)c2cc(Br)cc3CCN(C(=O)C)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N23 mock treatment 0.228 -0.0188 -1.01 -1.0109 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 N24 mock treatment 0.232 -0.0148 -0.8 -0.796 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O01 compound treatment 0.237 -0.00981 -0.53 -0.5273 -1.0 1601376 ChemDiv2_005589 Cn1c(=O)n(C)c2nc3n(CC(O)c4ccccc4)c(cn3c2c1=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O02 compound treatment 0.237 -0.00981 -0.53 -0.5273 -1.0 1986628 ChemDiv2_005590 CCc1c([nH]c2nc3n(C)c(=O)n(C)c(=O)c3n12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O03 compound treatment 0.347 0.1 5.38 5.3839 1.0 1471174 ChemDiv2_005591 CCOc1ccc2[nH]c(SCC(=O)NCc3ccccc3)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O04 compound treatment 0.253 0.00619 0.33 0.3325 1.0 1986629 ChemDiv2_005592 O=c1n(CC2CCCO2)c(=O)c3cc4c(=O)n(CC5CCCO5)c(=O)c4cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O05 compound treatment 0.255 0.00819 0.44 0.44 1.0 1702001 ChemDiv2_005593 Cn1c(=O)n(C)c2nc3n(C4CC4)c(cn3c2c1=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O06 compound treatment 0.329 0.0822 4.42 4.4166 1.0 1552671 ChemDiv2_005594 NCCc1c([nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O07 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986630 ChemDiv2_005595 O=C1C(=C(C(=O)c2ccccc12)n3nnc4ccccc34)Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O08 compound treatment 0.238 -0.00881 -0.47 -0.4736 -1.0 1986631 ChemDiv2_005596 CCCc1nn(c2CC(C)(C)CC(=O)c12)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O09 compound treatment 0.281 0.0342 1.84 1.8372 1.0 1453249 ChemDiv2_005597 COc1ccc(CNC(=O)c2n[nH]c(=O)c3ccccc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O10 compound treatment 0.286 0.0392 2.11 2.1059 1.0 1986632 ChemDiv2_005598 CCCn1c(CNS(=O)(=O)c2ccc(C)cc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O11 compound treatment 0.372 0.125 6.73 6.7273 1.0 1986633 ChemDiv2_005599 OC(=O)c1ccccc1NS(=O)(=O)c2cccc3N=S=Nc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O12 compound treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1986634 ChemDiv2_005600 Clc1ccc(C(=O)N(CC=C)c2nnc(s2)c3ccncc3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O13 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986635 ChemDiv2_005601 Cc1ccc(cc1Cl)N2CCN(CC2)C(=O)c3cc4cc(Br)ccc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O14 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986636 ChemDiv2_005602 CC(C)COC(=O)c1[nH]c2CC(CC(=O)c2c1C)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O15 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986637 ChemDiv2_005603 CSc1nn2c(=O)c(nnc2s1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O16 compound treatment 0.446 0.199 10.7 10.7039 1.0 1986638 ChemDiv2_005604 O=C(N1CCN(CC1)c2nc(cs2)c3ccccc3)c4nc[nH]n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O17 compound treatment 0.45 0.203 10.92 10.9189 1.0 1265853 ChemDiv2_005605 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O18 compound treatment 0.29 0.0432 2.32 2.3208 1.0 1986639 ChemDiv2_005606 CCOC(=O)c1c(CN2CCN(CC#N)CC2)oc3cc(Br)c(OC(=O)C)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O19 compound treatment 0.252 0.00519 0.28 0.2788 1.0 1986640 ChemDiv2_005607 Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c32)n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O20 compound treatment 0.255 0.00819 0.44 0.44 1.0 1986641 ChemDiv2_005608 COC(=O)CCC(=O)c1oc2ccccc2c1NC(=O)CCCN3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O21 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986642 ChemDiv2_005609 CC1(C)Cc2ccccc2C(=N1)c3sc4nc5CCCc5cc4c3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O22 compound treatment 0.243 -0.00381 -0.2 -0.2049 -1.0 1986643 ChemDiv2_005610 COc1ccc(NS(=O)(=O)N(C)C)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O23 mock treatment 0.261 0.0142 0.76 0.7624 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 O24 mock treatment 0.255 0.00819 0.44 0.44 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P01 compound treatment 0.328 0.0812 4.36 4.3628 1.0 1986644 ChemDiv2_005611 Clc1ccccc1OCc2nc(no2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P02 compound treatment 0.262 0.0152 0.82 0.8161 1.0 1294569 ChemDiv2_005612 COc1ccc(cc1)c2nnc(NC(=O)c3ccc(cc3)S(=O)(=O)N4CCCc5ccccc45)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P03 compound treatment 0.357 0.11 5.92 5.9212 1.0 1309803 ChemDiv2_005613 COc1ccc2nc(NC(=O)CCCN3C(=O)C4C5CC(C=C5)C4C3=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P04 compound treatment 0.238 -0.00881 -0.47 -0.4736 -1.0 1986645 ChemDiv2_005614 CCCCN(Cc1ccccc1)C(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P05 compound treatment 0.251 0.00419 0.23 0.225 1.0 1187162 ChemDiv2_005615 O=C(NCc1ccccc1)c2cnc3SCCn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P06 compound treatment 0.242 -0.00481 -0.26 -0.2586 -1.0 1986646 ChemDiv2_005616 OC(=O)CCCNc1cc(N2CCCC2)c3noc4-c5ccccc5C(=O)c1c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P07 compound treatment 0.228 -0.0188 -1.01 -1.0109 -1.0 1986647 ChemDiv2_005617 CC1CCCC(NC(=O)c2n[nH]c(=O)c3ccccc23)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P08 compound treatment 0.277 0.0302 1.62 1.6222 1.0 1986648 ChemDiv2_005618 Cc1ccc(CC(=O)Nc2ccc3nc(cc(C)c3c2)N4CCN(CC4)c5ncccn5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P09 compound treatment 0.229 -0.0178 -0.96 -0.9572 -1.0 1986649 ChemDiv2_005619 CN(C(=O)c1cnc(N2CCN(CC2)c3ncccn3)c4ccccc14)c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P10 compound treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1986650 ChemDiv2_005620 COc1ccc(cc1)C2C(C(=O)Nc3ccccc3F)c4ccccc4C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P11 compound treatment 0.227 -0.0198 -1.06 -1.0647 -1.0 1986651 ChemDiv2_005621 COC(=O)Cn1cnc2sc(C)c(c2c1=O)S(=O)(=O)N3CCC(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P12 compound treatment 0.231 -0.0158 -0.85 -0.8497 -1.0 1986652 ChemDiv2_005622 CN(Cc1ccccc1)c2nc3n(C)c(=O)n(C)c(=O)c3n2CCSc4nnc(C)s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P13 compound treatment 0.237 -0.00981 -0.53 -0.5273 -1.0 1986653 ChemDiv2_005623 CCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c4cc(OC)ccc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P14 compound treatment 0.237 -0.00981 -0.53 -0.5273 -1.0 1986654 ChemDiv2_005624 Cc1ccccc1NC(=O)CCS(=O)(=O)c2cccc3nonc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P15 compound treatment 0.268 0.0212 1.14 1.1386 1.0 1986655 ChemDiv2_005625 O=C(NC1CCc2ccccc2C1)c3cc4c(=O)oc5ccccc5c4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P16 compound treatment 0.245 -0.00181 -0.1 -0.0974 -1.0 1986656 ChemDiv2_005626 Clc1ccc(CNS(=O)(=O)c2cccc3nsnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P17 compound treatment 0.238 -0.00881 -0.47 -0.4736 -1.0 1986657 ChemDiv2_005627 O=C(Nc1cccnc1)C2C3N(CCc4ccccc34)C(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P18 compound treatment 0.299 0.0522 2.8 2.8044 1.0 1872415 ChemDiv2_005628 C/C(=C\c1nsc(Nc2ccccc2)n1)/NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P19 compound treatment 0.292 0.0452 2.43 2.4283 1.0 1986658 ChemDiv2_005629 COc1ccccc1NC(=O)c2ccc3c(Cl)c4CCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P20 compound treatment 0.232 -0.0148 -0.8 -0.796 -1.0 1986659 ChemDiv2_005630 CCN1CCN(CCCNC(=O)C2C(N(C)C(=O)c3cc(OC)c(OC)cc23)c4cccnc4)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P21 compound treatment 0.279 0.0322 1.73 1.7297 1.0 1986660 ChemDiv2_005631 COc1cc(OC)c(NC(=O)c2ccc3c(=O)n4CCCCCc4nc3c2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P22 compound treatment 0.307 0.0602 3.23 3.2344 1.0 1986661 ChemDiv2_005632 O=C(CCS(=O)(=O)c1cccs1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P23 mock treatment 0.239 -0.00781 -0.42 -0.4198 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1384 P24 mock treatment 0.244 -0.00281 -0.15 -0.1511 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A01 compound treatment 0.28 0.0284 1.53 1.5282 1.0 1986662 ChemDiv2_005633 CN(Cc1ccccc1)C(=O)CNS(=O)(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A02 compound treatment 0.228 -0.0236 -1.27 -1.2662 -1.0 1986663 ChemDiv2_005634 CC1CCC(CC1)NC(=O)CCc2nc3sc4CCCCc4c3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A03 compound treatment 0.282 0.0304 1.64 1.6356 1.0 1986664 ChemDiv2_005635 COc1cccc(CNC(=O)CCS(=O)(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A04 compound treatment 0.259 0.00744 0.4 0.3997 1.0 1986665 ChemDiv2_005636 CCC(=O)NCCc1nc2ccccc2n1CC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A05 compound treatment 0.529 0.277 14.91 14.9089 1.0 1986666 ChemDiv2_005637 CC1Cc2cc(Br)cc(c2N1C(=O)C)S(=O)(=O)N3CCN(CC3)C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A06 compound treatment 0.346 0.0944 5.07 5.0749 1.0 1986667 ChemDiv2_005638 O=C(Nc1ccc(cc1)C(=O)NCc2ccc3OCOc3c2)C4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A07 compound treatment 0.305 0.0534 2.87 2.8716 1.0 1613496 ChemDiv2_005639 Cn1c(SCC(=O)Nc2ccc3OCOc3c2)nc4c5ccccc5[nH]c4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A08 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986668 ChemDiv2_005640 CCC1CCCCN1C(=O)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A09 compound treatment 0.259 0.00744 0.4 0.3997 1.0 1145337 ChemDiv2_005641 Cc1nnc(NC(=O)CSc2nc3c4ccccc4[nH]c3c(=O)n2c5ccc(F)cc5)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A10 compound treatment 0.428 0.176 9.48 9.4814 1.0 1986669 ChemDiv2_005642 COc1ccc(Cn2c(=O)[nH]c3cc(ccc3c2=O)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A11 compound treatment 0.26 0.00844 0.45 0.4534 1.0 1986670 ChemDiv2_005643 CCc1ccccc1NC(=O)c2sc3[nH]c(=O)c(cc3c2N)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A12 compound treatment 0.306 0.0544 2.93 2.9254 1.0 1986671 ChemDiv2_005644 CCOC(=O)N1CCN(CC1)C(=O)c2ccc(Cn3c(=O)[nH]c4cc(OC)c(OC)cc4c3=O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A13 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986672 ChemDiv2_005645 CCN1CCCC1CNC(=O)C(NC(=O)C2CCC(C)CC2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A14 compound treatment 0.246 -0.00556 -0.3 -0.2989 -1.0 1986673 ChemDiv2_005646 CN(C(=O)Cc1c([nH]c2ccccc12)C(=O)O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A15 compound treatment 0.257 0.00544 0.29 0.2922 1.0 1986674 ChemDiv2_005647 CC1CCC(CC1)C(=O)NC(Cc2ccccc2)C(=O)NCc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A16 compound treatment 0.252 4.37E-4 0.02 0.0235 1.0 1986675 ChemDiv2_005648 COc1cc(cc(OC)c1OC)n2c(=O)n(CC(=O)NCc3ccco3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A17 compound treatment 0.259 0.00744 0.4 0.3997 1.0 1986676 ChemDiv2_005649 COc1ccc(cc1)c2nc(nc3[nH]nc(N)c23)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A18 compound treatment 0.263 0.0114 0.61 0.6146 1.0 1986677 ChemDiv2_005650 COc1cc(OC)cc(c1)n2c(=O)[nH]c3cc(ccc3c2=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A19 compound treatment 0.28 0.0284 1.53 1.5282 1.0 1986678 ChemDiv2_005651 Cc1ccc(o1)c2nc3cnccn3c2Nc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A20 compound treatment 0.26 0.00844 0.45 0.4534 1.0 1986679 ChemDiv2_005652 COc1ccccc1NC2=NC3CS(=O)(=O)CC3S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A21 compound treatment 0.383 0.131 7.06 7.0632 1.0 1986680 ChemDiv2_005653 O=C(CCCCn1c(=O)[nH]c2ccsc2c1=O)N3CCN(Cc4ccc5OCOc5c4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A22 compound treatment 0.265 0.0134 0.72 0.7221 1.0 1986681 ChemDiv2_005654 COc1ccccc1NC(=O)C2=C(C)Nc3nc4ccccc4n3C2c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A23 mock treatment 0.242 -0.00956 -0.51 -0.5139 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 A24 mock treatment 0.272 0.0204 1.1 1.0983 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B01 compound treatment 0.229 -0.0226 -1.21 -1.2125 -1.0 1551320 ChemDiv2_005655 CN(Cc1ccccc1)S(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B02 compound treatment 0.296 0.0444 2.39 2.388 1.0 1986682 ChemDiv2_005656 CN(Cc1ccccc1)C(=O)c2cc(on2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B03 compound treatment 0.507 0.255 13.73 13.7267 1.0 1986683 ChemDiv2_005657 CCN(CC)C(=O)COc1ccc2OC3(CCN(CC3)C(=O)C)CC(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B04 compound treatment 0.263 0.0114 0.61 0.6146 1.0 1986684 ChemDiv2_005658 CC1CCc2c(C(=O)N)c(NC(=O)c3cc(on3)c4ccc5OCOc5c4)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B05 compound treatment 0.483 0.231 12.44 12.437 1.0 1986685 ChemDiv2_005659 CCOC(=O)N1CCN(CC1)C(=O)COc2ccc3OC(C)(C)CC(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B06 compound treatment 0.294 0.0424 2.28 2.2805 1.0 1986686 ChemDiv2_005660 CN(C(=O)c1cc(on1)c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B07 compound treatment 0.475 0.223 12.01 12.0071 1.0 1986687 ChemDiv2_005661 CCn1cnc2cc(NCc3ccncc3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B08 compound treatment 0.286 0.0344 1.85 1.8506 1.0 1986688 ChemDiv2_005662 COc1ccc(Cl)cc1NC(=O)c2cc(on2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B09 compound treatment 0.275 0.0234 1.26 1.2595 1.0 1986689 ChemDiv2_005663 CC(C)C(NS(=O)(=O)c1cccs1)C(=O)NCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B10 compound treatment 0.422 0.17 9.16 9.159 1.0 1986690 ChemDiv2_005664 Oc1ccccc1c2cc(no2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B11 compound treatment 0.579 0.327 17.6 17.5958 1.0 1986691 ChemDiv2_005665 CN(c1ccc(Br)cc1)S(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B12 compound treatment 0.366 0.114 6.15 6.1496 1.0 1986692 ChemDiv2_005666 Cc1cc(no1)C(=O)Nc2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B13 compound treatment 0.48 0.228 12.28 12.2758 1.0 1986693 ChemDiv2_005667 CN(Cc1ccccc1)C(=O)c2cc(on2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B14 compound treatment 0.394 0.142 7.65 7.6543 1.0 1986694 ChemDiv2_005668 Brc1ccc(NC(=O)c2cc(on2)C3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B15 compound treatment 0.343 0.0914 4.91 4.9137 1.0 1986695 ChemDiv2_005669 Clc1ccc(cc1)c2cc(no2)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B16 compound treatment 0.38 0.128 6.9 6.902 1.0 1986696 ChemDiv2_005670 CC(C)c1cc(no1)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B17 compound treatment 0.338 0.0864 4.64 4.645 1.0 1986697 ChemDiv2_005671 CN(C(=O)c1cc(on1)c2ccc(O)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B18 compound treatment 0.445 0.193 10.39 10.3949 1.0 1986698 ChemDiv2_005672 CCCc1cc(no1)C(=O)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B19 compound treatment 0.475 0.223 12.01 12.0071 1.0 1986699 ChemDiv2_005673 COc1ccc(cc1)c2cc(no2)C(=O)NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B20 compound treatment 0.274 0.0224 1.21 1.2057 1.0 1986700 ChemDiv2_005674 Cc1ccc(NC(=O)c2noc3CCCc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B21 compound treatment 0.391 0.139 7.49 7.4931 1.0 1986701 ChemDiv2_005675 CCN(CC)C(=O)c1cc(on1)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B22 compound treatment 0.239 -0.0126 -0.68 -0.6751 -1.0 1986702 ChemDiv2_005676 CCc1ccccc1NC(=O)c2noc3CCCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B23 mock treatment 0.276 0.0244 1.31 1.3132 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 B24 mock treatment 0.241 -0.0106 -0.57 -0.5676 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C01 compound treatment 0.313 0.0614 3.3 3.3015 1.0 1986703 ChemDiv2_005677 Cc1ccc(C)c(c1)N2CCN(CC2)C(=O)CNS(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C02 compound treatment 0.267 0.0154 0.83 0.8296 1.0 1986704 ChemDiv2_005678 O=C(CCc1nc2sc3CCCCc3c2c(=O)[nH]1)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C03 compound treatment 0.339 0.0874 4.7 4.6987 1.0 1986705 ChemDiv2_005679 CC1Cc2ccccc2N1C(=O)CCS(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C04 compound treatment 0.257 0.00544 0.29 0.2922 1.0 1986706 ChemDiv2_005680 CC(C)(C)C(=O)NCCCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C05 compound treatment 0.568 0.316 17.0 17.0047 1.0 1986707 ChemDiv2_005681 CC1Cc2cc(Br)cc(c2N1C(=O)C)S(=O)(=O)N3CCN(C(C)C3)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C06 compound treatment 0.317 0.0654 3.52 3.5165 1.0 1986708 ChemDiv2_005682 O=C(Nc1ccc(cc1)C(=O)NCc2cccs2)C3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C07 compound treatment 0.429 0.177 9.54 9.5351 1.0 1453562 ChemDiv2_005683 COC(=O)c1ccc(CSc2nc3c4ccccc4[nH]c3c(=O)n2C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C08 compound treatment 0.474 0.222 11.95 11.9533 1.0 1986709 ChemDiv2_005684 CN(CCc1ccccn1)C(=O)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C09 compound treatment 0.353 0.101 5.45 5.451 1.0 1986710 ChemDiv2_005685 Cn1c(CNC(c2ccccc2)c3ccccc3)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C10 compound treatment 0.362 0.11 5.93 5.9347 1.0 1986711 ChemDiv2_005686 COCCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C11 compound treatment 0.552 0.3 16.14 16.1449 1.0 1986712 ChemDiv2_005687 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)NCCc3ccc(OC)c(OC)c3)c(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C12 compound treatment 0.272 0.0204 1.1 1.0983 1.0 1986713 ChemDiv2_005688 OC(=O)c1[nH]c2ccccc2c1CC(=O)Nc3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C13 compound treatment 0.24 -0.0116 -0.62 -0.6213 -1.0 1986714 ChemDiv2_005689 CC(C)C(NC(=O)C1CCC(C)CC1)C(=O)N2CCC(CC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C14 compound treatment 0.293 0.0414 2.23 2.2268 1.0 1986715 ChemDiv2_005690 OC(=O)c1[nH]c2ccccc2c1CC(=O)NCCN3CCN(CC3)c4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C15 compound treatment 0.246 -0.00556 -0.3 -0.2989 -1.0 1986716 ChemDiv2_005691 CC(C)C(NC(=O)C1CCC(C)CC1)C(=O)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C16 compound treatment 0.248 -0.00356 -0.19 -0.1914 -1.0 1986717 ChemDiv2_005692 Fc1ccc(cc1)n2c(=O)n(CC(=O)NCc3ccccc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C17 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986718 ChemDiv2_005693 Cc1cc(C)n2nc3nc(nc(c4ccccc4)c3c2n1)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C18 compound treatment 0.236 -0.0156 -0.84 -0.8363 -1.0 1986719 ChemDiv2_005694 COc1ccc(C2NC(C3C2C(=O)N(C3=O)c4ccc(F)cc4)C(=O)O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C19 compound treatment 0.288 0.0364 1.96 1.9581 1.0 1986720 ChemDiv2_005695 C1COc2cc(Nc3c(nc4cnccn34)c5ccccc5)ccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C20 compound treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1986721 ChemDiv2_005696 CN(C)C(=O)c1sc2[nH]c(=O)n(c3ccc(F)cc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C21 compound treatment 0.409 0.157 8.46 8.4604 1.0 1986722 ChemDiv2_005697 O=C(N1CCN(CC1)c2ccccn2)c3ccc(Cn4c(=O)[nH]c5ccsc5c4=O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C22 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986723 ChemDiv2_005698 CCc1cccc(NC(=O)c2ccc(Cn3c(=O)[nH]c4ccsc4c3=O)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C23 mock treatment 0.254 0.00244 0.13 0.131 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 C24 mock treatment 0.261 0.00944 0.51 0.5072 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D01 compound treatment 0.234 -0.0176 -0.94 -0.9438 -1.0 1986724 ChemDiv2_005699 Cc1cccc(NS(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D02 compound treatment 0.251 -5.63E-4 -0.03 -0.0302 -1.0 1986725 ChemDiv2_005700 CC1CCCC(C)N1C(=O)c2cc(on2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D03 compound treatment 0.481 0.229 12.33 12.3295 1.0 1986726 ChemDiv2_005701 O=C(COc1ccc2OC3(CCCCC3)CC(=O)c2c1)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D04 compound treatment 0.265 0.0134 0.72 0.7221 1.0 1986727 ChemDiv2_005702 Clc1cccc(NC(=O)c2cc(on2)c3cccc(Cl)c3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D05 compound treatment 0.485 0.233 12.54 12.5444 1.0 1986728 ChemDiv2_005703 Cc1ccc(CNc2ccc3n(C)cnc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D06 compound treatment 0.505 0.253 13.62 13.6192 1.0 1986729 ChemDiv2_005704 O=C(NCCN1CCOCC1)c2cc(on2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D07 compound treatment 0.436 0.184 9.91 9.9113 1.0 1986730 ChemDiv2_005705 Cn1cnc2cc(NCc3cccs3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D08 compound treatment 0.387 0.135 7.28 7.2781 1.0 1986731 ChemDiv2_005706 Cc1ccc(NC(=O)c2cc(on2)c3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D09 compound treatment 0.264 0.0124 0.67 0.6684 1.0 1986732 ChemDiv2_005707 CC(C)C(NS(=O)(=O)c1cccs1)C(=O)Nc2nc(cs2)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D10 compound treatment 0.314 0.0624 3.36 3.3553 1.0 1986733 ChemDiv2_005708 CC1(CC2CC(C)(C)C1)CN2C(=O)c3cc(on3)c4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D11 compound treatment 0.247 -0.00456 -0.25 -0.2452 -1.0 1986734 ChemDiv2_005709 CC1CCCCN1S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D12 compound treatment 0.353 0.101 5.45 5.451 1.0 1986735 ChemDiv2_005710 Cc1cc(no1)C(=O)Nc2cnn(Cc3ccccc3C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D13 compound treatment 0.46 0.208 11.2 11.201 1.0 1986736 ChemDiv2_005711 Fc1ccc(cc1)c2cc(no2)C(=O)NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D14 compound treatment 0.287 0.0354 1.9 1.9043 1.0 1986737 ChemDiv2_005712 COc1cc(NC(=O)c2cc(on2)C3CC3)c(OC)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D15 compound treatment 0.313 0.0614 3.3 3.3015 1.0 1986738 ChemDiv2_005713 Brc1ccc(cc1)c2cc(no2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D16 compound treatment 0.349 0.0974 5.24 5.2361 1.0 1986739 ChemDiv2_005714 CCCc1cc(no1)C(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D17 compound treatment 0.345 0.0934 5.02 5.0211 1.0 1986740 ChemDiv2_005715 Oc1ccc(cc1)c2cc(no2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D18 compound treatment 0.249 -0.00256 -0.14 -0.1377 -1.0 1986741 ChemDiv2_005716 CC(C)Cc1cc(no1)C(=O)NCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D19 compound treatment 0.331 0.0794 4.27 4.2688 1.0 1986742 ChemDiv2_005717 COc1ccc(cc1)c2cc(no2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D20 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986743 ChemDiv2_005718 O=C(NC1CCCCC1)c2noc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D21 compound treatment 0.331 0.0794 4.27 4.2688 1.0 1986744 ChemDiv2_005719 COc1ccc(cc1)c2cc(no2)C(=O)Nc3ccc(C)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D22 compound treatment 0.246 -0.00556 -0.3 -0.2989 -1.0 1986745 ChemDiv2_005720 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2noc3CCCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D23 mock treatment 0.247 -0.00456 -0.25 -0.2452 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 D24 mock treatment 0.247 -0.00456 -0.25 -0.2452 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E01 compound treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1986746 ChemDiv2_005721 Cc1cccc(NC(=O)CNS(=O)(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E02 compound treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1986747 ChemDiv2_005722 CCn1c(CNC(=O)C)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E03 compound treatment 0.516 0.264 14.21 14.2103 1.0 1986748 ChemDiv2_005723 CCOC(=O)c1cccc(NC(=O)CNS(=O)(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E04 compound treatment 0.429 0.177 9.54 9.5351 1.0 1986749 ChemDiv2_005724 CCCNC(=O)CSc1nc2nc(C)c(Cc3ccccc3C)c(C)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E05 compound treatment 0.234 -0.0176 -0.94 -0.9438 -1.0 1986750 ChemDiv2_005725 COc1ccc(cc1)C2C(CCC(=O)N2c3ccc4OCOc4c3)C(=O)NCC5CCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E06 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986751 ChemDiv2_005726 CC1CCN(CCNC(=O)c2ccc(NC(=O)C3CCCO3)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E07 compound treatment 0.332 0.0804 4.32 4.3225 1.0 1128466 ChemDiv2_005727 CCOC(=O)C(C)Sc1nc2c3ccccc3[nH]c2c(=O)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E08 compound treatment 0.238 -0.0136 -0.73 -0.7288 -1.0 1986752 ChemDiv2_005728 COc1ccc(cc1)C2C(CCC(=O)N2c3cc(OC)c(OC)c(OC)c3)C(=O)N4CCCC(C)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E09 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1372840 ChemDiv2_005729 CCn1c(CNc2ccc(cc2)C(=O)O)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E10 compound treatment 0.446 0.194 10.45 10.4487 1.0 1986753 ChemDiv2_005730 COc1ccc(Cn2c(=O)[nH]c3cc(ccc3c2=O)C(=O)NCCCN4CCCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E11 compound treatment 0.506 0.254 13.67 13.6729 1.0 1986754 ChemDiv2_005731 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)NCCCN3CCOCC3)c(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E12 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986755 ChemDiv2_005732 COc1ccc(NC(=O)Cc2c([nH]c3ccccc23)C(=O)O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E13 compound treatment 0.26 0.00844 0.45 0.4534 1.0 1986756 ChemDiv2_005733 CC(C)C(NC(=O)C1CCC(C)CC1)C(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E14 compound treatment 0.249 -0.00256 -0.14 -0.1377 -1.0 1986757 ChemDiv2_005734 O=C(NC1CCCCC1)c2ccc3c(=O)n(c4ccccc4)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E15 compound treatment 0.294 0.0424 2.28 2.2805 1.0 1986758 ChemDiv2_005735 CCC(C)C(NC(=O)C1CCC(C)CC1)C(=O)Nc2cc(OC)ccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E16 compound treatment 0.254 0.00244 0.13 0.131 1.0 1986759 ChemDiv2_005736 COc1ccc(CCNC(=O)Cn2c(=O)[nH]c3ccsc3c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E17 compound treatment 0.276 0.0244 1.31 1.3132 1.0 1986760 ChemDiv2_005737 Oc1nc(nc(c1C#N)c2ccccc2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E18 compound treatment 0.495 0.243 13.08 13.0818 1.0 1986761 ChemDiv2_005738 COc1ccc(NC(=O)CCCn2c(=O)n(CC(=O)c3ccccc3)c4ccsc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E19 compound treatment 0.38 0.128 6.9 6.902 1.0 1986762 ChemDiv2_005739 Oc1ccccc1c2nc3cnccn3c2Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E20 compound treatment 0.268 0.0164 0.88 0.8833 1.0 1986763 ChemDiv2_005740 CSc1nc2c3ccccc3sc2c(=O)n1CCCC(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E21 compound treatment 0.317 0.0654 3.52 3.5165 1.0 1986764 ChemDiv2_005741 COc1ccc(CNC(=O)C2CCC(Cn3c(=O)[nH]c4ccsc4c3=O)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E22 compound treatment 0.324 0.0724 3.89 3.8926 1.0 1986765 ChemDiv2_005742 CCN1CCN(CC1)c2cc(C)c3cc(NC(=O)CCC(=O)Nc4ccc(OC)c(OC)c4)ccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E23 mock treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 E24 mock treatment 0.26 0.00844 0.45 0.4534 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F01 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986766 ChemDiv2_005743 CC1CCCCC1NS(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F02 compound treatment 0.334 0.0824 4.43 4.43 1.0 1986767 ChemDiv2_005744 O=C(NCCc1ccccc1)c2cc(on2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F03 compound treatment 0.438 0.186 10.02 10.0188 1.0 1986768 ChemDiv2_005745 O=C(COc1ccc2OC3(CCCCC3)CC(=O)c2c1)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F04 compound treatment 0.443 0.191 10.29 10.2875 1.0 1986769 ChemDiv2_005746 CN(Cc1ccccc1)C(=O)c2cc(on2)c3cccc(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F05 compound treatment 0.514 0.262 14.1 14.1028 1.0 1986770 ChemDiv2_005747 CC(C)(C)n1cnc2cc(NCc3ccccc3O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F06 compound treatment 0.339 0.0874 4.7 4.6987 1.0 1986771 ChemDiv2_005748 O=C(N1CCCCC1)c2cc(on2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F07 compound treatment 0.459 0.207 11.15 11.1473 1.0 1986772 ChemDiv2_005749 CCn1cnc2cc(NCc3cccs3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F08 compound treatment 0.366 0.114 6.15 6.1496 1.0 1986773 ChemDiv2_005750 CCC1CCCCN1C(=O)c2cc(on2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F09 compound treatment 0.537 0.285 15.34 15.3388 1.0 1351971 ChemDiv2_005751 COc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F10 compound treatment 0.284 0.0324 1.74 1.7431 1.0 1986774 ChemDiv2_005752 CCc1ccccc1NC(=O)c2cc(on2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F11 compound treatment 0.254 0.00244 0.13 0.131 1.0 1986775 ChemDiv2_005753 CN(C)CCN(Cc1ccccc1)S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F12 compound treatment 0.273 0.0214 1.15 1.152 1.0 1986776 ChemDiv2_005754 O=C(NC1CCCC1)c2cc(on2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F13 compound treatment 0.412 0.16 8.62 8.6216 1.0 1986777 ChemDiv2_005755 CCC1CCCCN1C(=O)c2cc(on2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F14 compound treatment 0.359 0.107 5.77 5.7735 1.0 1986778 ChemDiv2_005756 O=C(Nc1cccnc1)c2cc(on2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F15 compound treatment 0.495 0.243 13.08 13.0818 1.0 1986779 ChemDiv2_005757 CC(C)NC(=O)c1cc(on1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F16 compound treatment 0.511 0.259 13.94 13.9416 1.0 1986780 ChemDiv2_005758 CCCc1cc(no1)C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F17 compound treatment 0.389 0.137 7.39 7.3856 1.0 1986781 ChemDiv2_005759 CCC(C)NC(=O)c1cc(on1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F18 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986782 ChemDiv2_005760 CC(C)Cc1cc(no1)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F19 compound treatment 0.273 0.0214 1.15 1.152 1.0 1986783 ChemDiv2_005761 COc1ccc(cc1)c2cc(no2)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F20 compound treatment 0.27 0.0184 0.99 0.9908 1.0 1986784 ChemDiv2_005762 O=C(NCc1ccccc1)c2noc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F21 compound treatment 0.415 0.163 8.78 8.7828 1.0 1986785 ChemDiv2_005763 CCCNC(=O)c1cc(on1)c2cccc(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F22 compound treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1986786 ChemDiv2_005764 CC(C)(C)C1CCc2onc(C(=O)Nc3ccc(C#N)cc3)c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F23 mock treatment 0.261 0.00944 0.51 0.5072 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 F24 mock treatment 0.246 -0.00556 -0.3 -0.2989 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G01 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986787 ChemDiv2_005765 O=C(CNS(=O)(=O)c1cccs1)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G02 compound treatment 0.239 -0.0126 -0.68 -0.6751 -1.0 1986788 ChemDiv2_005766 CCCn1c(CNC(=O)C)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G03 compound treatment 0.334 0.0824 4.43 4.43 1.0 1986789 ChemDiv2_005767 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)NC(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G04 compound treatment 0.414 0.162 8.73 8.7291 1.0 1986790 ChemDiv2_005768 Cc1nc2nc(SCC(=O)NC3CC3)nn2c(C)c1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G05 compound treatment 0.256 0.00444 0.24 0.2385 1.0 1986791 ChemDiv2_005769 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(F)c(Br)c3)C(=O)C(C(C)C2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G06 compound treatment 0.412 0.16 8.62 8.6216 1.0 1986792 ChemDiv2_005770 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)CCC(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G07 compound treatment 0.239 -0.0126 -0.68 -0.6751 -1.0 1642046 ChemDiv2_005771 CCOC(=O)N1CCN(CC1)C(=O)CSc2nc3c4ccccc4[nH]c3c(=O)n2c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G08 compound treatment 0.24 -0.0116 -0.62 -0.6213 -1.0 1986793 ChemDiv2_005772 CCN1CCN(CC1)C(=O)C2CCC(=O)N(C2c3ccc(OC)cc3)c4cc(OC)c(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G09 compound treatment 0.285 0.0334 1.8 1.7969 1.0 1779437 ChemDiv2_005773 OC(=O)c1ccc(NCc2nc3ccccc3n2Cc4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G10 compound treatment 0.248 -0.00356 -0.19 -0.1914 -1.0 1986794 ChemDiv2_005774 COc1ccc(CCNC(=O)c2ccc3c(=O)n(CCc4ccccc4)c(=O)[nH]c3c2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G11 compound treatment 0.432 0.18 9.7 9.6963 1.0 1986795 ChemDiv2_005775 COc1ccc(CNC(=O)c2oc3ccc(cc3c2C)S(=O)(=O)N4CCOCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G12 compound treatment 0.294 0.0424 2.28 2.2805 1.0 1986796 ChemDiv2_005776 COC(=O)c1ccccc1NC(=O)Cc2c([nH]c3ccccc23)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G13 compound treatment 0.243 -0.00856 -0.46 -0.4601 -1.0 1986797 ChemDiv2_005777 CCOC(=O)N1CCN(CC1)C(=O)C(CC(C)C)NC(=O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G14 compound treatment 0.347 0.0954 5.13 5.1286 1.0 1986798 ChemDiv2_005778 C=CCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G15 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986799 ChemDiv2_005779 CC(C)CCNC(=O)C1CCCCN1S(=O)(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G16 compound treatment 0.248 -0.00356 -0.19 -0.1914 -1.0 1986800 ChemDiv2_005780 O=C(Cn1c(=O)[nH]c2ccsc2c1=O)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G17 compound treatment 0.482 0.23 12.38 12.3832 1.0 1986801 ChemDiv2_005781 COc1ccc(cc1)c2nc(nc(O)c2C#N)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G18 compound treatment 0.474 0.222 11.95 11.9533 1.0 1986802 ChemDiv2_005782 COc1ccc(NC(=O)CCCn2c(=O)n(Cc3ccccc3F)c4ccsc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G19 compound treatment 0.3 0.0484 2.6 2.6029 1.0 1986803 ChemDiv2_005783 N(c1c(nc2cnccn12)c3ccsc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G20 compound treatment 0.449 0.197 10.61 10.6099 1.0 1986804 ChemDiv2_005784 CCOC(=O)N1CCc2c(C1)sc3n(CC(=O)Nc4ccccc4F)c(=O)n(c5ccccc5)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G21 compound treatment 0.37 0.118 6.36 6.3646 1.0 1986805 ChemDiv2_005785 O=C(NC1CCCC1)c2ccc(Cn3c(=O)[nH]c4ccsc4c3=O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G22 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986806 ChemDiv2_005786 CN(Cc1ccccc1)C(=O)CN2C(=O)COc3ccc(C)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G23 mock treatment 0.251 -5.63E-4 -0.03 -0.0302 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 G24 mock treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H01 compound treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1986807 ChemDiv2_005787 CC1CCc2cc(F)ccc2N1S(=O)(=O)c3c(C)[nH]c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H02 compound treatment 0.278 0.0264 1.42 1.4207 1.0 1986808 ChemDiv2_005788 O=C(N1CCCCC1)c2cc(on2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H03 compound treatment 0.496 0.244 13.14 13.1356 1.0 1986809 ChemDiv2_005789 O=C(COc1ccc2OC3(CCCCC3)CC(=O)c2c1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H04 compound treatment 0.452 0.2 10.77 10.7711 1.0 1986810 ChemDiv2_005790 Oc1cccc(c1)c2cc(no2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H05 compound treatment 0.51 0.258 13.89 13.8879 1.0 1986811 ChemDiv2_005791 Cn1cnc2cc(NCc3ccccc3Cl)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H06 compound treatment 0.492 0.24 12.92 12.9206 1.0 1986812 ChemDiv2_005792 COc1ccc(CCNC(=O)c2cc(on2)c3ccco3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H07 compound treatment 0.477 0.225 12.11 12.1145 1.0 1986813 ChemDiv2_005793 CCCCn1cnc2cc(NCc3cccs3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H08 compound treatment 0.491 0.239 12.87 12.8669 1.0 1986814 ChemDiv2_005794 O=C(NCCc1ccccc1)c2cc(on2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H09 compound treatment 0.517 0.265 14.26 14.2641 1.0 1312006 ChemDiv2_005795 O=c1[nH]c2ccc(cc2[nH]c1=O)S(=O)(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H10 compound treatment 0.327 0.0754 4.05 4.0539 1.0 1986815 ChemDiv2_005796 COC(=O)c1ccccc1NC(=O)c2cc(on2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H11 compound treatment 0.259 0.00744 0.4 0.3997 1.0 1986816 ChemDiv2_005797 O=S(=O)(NCCN1CCCC1)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H12 compound treatment 0.304 0.0524 2.82 2.8179 1.0 1986817 ChemDiv2_005798 O=C(N1CCCC1)c2cc(on2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H13 compound treatment 0.308 0.0564 3.03 3.0328 1.0 1986818 ChemDiv2_005799 CC1CCCC(C)N1C(=O)c2cc(on2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H14 compound treatment 0.266 0.0144 0.78 0.7758 1.0 1986819 ChemDiv2_005800 CC(C)c1cc(no1)C(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H15 compound treatment 0.429 0.177 9.54 9.5351 1.0 1986820 ChemDiv2_005801 CCN(CC)C(=O)c1cc(on1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H16 compound treatment 0.446 0.194 10.45 10.4487 1.0 1986821 ChemDiv2_005802 CCCc1cc(no1)C(=O)NCCc2ccc(OC)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H17 compound treatment 0.519 0.267 14.37 14.3715 1.0 1986822 ChemDiv2_005803 Oc1ccc(cc1)c2cc(no2)C(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H18 compound treatment 0.266 0.0144 0.78 0.7758 1.0 1986823 ChemDiv2_005804 CCc1ccccc1NC(=O)c2cc(CC(C)C)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H19 compound treatment 0.501 0.249 13.4 13.4042 1.0 1986824 ChemDiv2_005805 COc1ccc(cc1)c2cc(no2)C(=O)NCCCn3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H20 compound treatment 0.271 0.0194 1.04 1.0445 1.0 1986825 ChemDiv2_005806 O=C(N1CCCC1)c2noc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H21 compound treatment 0.506 0.254 13.67 13.6729 1.0 1986826 ChemDiv2_005807 COc1cccc(c1)c2cc(no2)C(=O)Nc3cccc(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H22 compound treatment 0.429 0.177 9.54 9.5351 1.0 1986827 ChemDiv2_005808 O=C(NC1CCCC1)c2noc-3c2CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H23 mock treatment 0.248 -0.00356 -0.19 -0.1914 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 H24 mock treatment 0.241 -0.0106 -0.57 -0.5676 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I01 compound treatment 0.271 0.0194 1.04 1.0445 1.0 1986828 ChemDiv2_005809 CCN(CCN(C)C)S(=O)(=O)c1cc(Br)cc2CCN(C(=O)CC)c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I02 compound treatment 0.232 -0.0196 -1.05 -1.0512 -1.0 1986829 ChemDiv2_005810 CC(=O)NCc1nc2ccccc2n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I03 compound treatment 0.367 0.115 6.2 6.2034 1.0 1986830 ChemDiv2_005811 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)N(C)c3ccc(OC)cc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I04 compound treatment 0.332 0.0804 4.32 4.3225 1.0 1986831 ChemDiv2_005812 Cc1nc2nc(SCC(=O)NCC3COc4ccccc4O3)nn2c(C)c1Cc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I05 compound treatment 0.234 -0.0176 -0.94 -0.9438 -1.0 1986832 ChemDiv2_005813 COC(=O)C1C(C)CC2=C(C(C(=C(C)N2)C(=O)OC(C)C)c3coc4ccccc4c3=O)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I06 compound treatment 0.56 0.308 16.57 16.5748 1.0 1986833 ChemDiv2_005814 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)CCC(=O)N(C)c3ccc(OC)cc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I07 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1529500 ChemDiv2_005815 COc1cccc(c1)n2c(SCC(=O)N3CCC(C)CC3)nc4c5ccccc5[nH]c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I08 compound treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1986834 ChemDiv2_005816 CC1CC(C)CN(C1)S(=O)(=O)c2c(C)sc3ncn(CC(=O)NCC4COc5ccccc5O4)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I09 compound treatment 0.347 0.0954 5.13 5.1286 1.0 1457639 ChemDiv2_005817 Cn1c(CNc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I10 compound treatment 0.436 0.184 9.91 9.9113 1.0 1986835 ChemDiv2_005818 CCN1CCN(CCCNC(=O)c2ccc3c(=O)n(CCc4ccccc4)c(=O)[nH]c3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I11 compound treatment 0.524 0.272 14.64 14.6402 1.0 1986836 ChemDiv2_005819 CN(Cc1ccccc1)C(=O)c2oc3ccc(cc3c2C)S(=O)(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I12 compound treatment 0.238 -0.0136 -0.73 -0.7288 -1.0 1986837 ChemDiv2_005820 CC(C)NC(=O)Cc1c([nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I13 compound treatment 0.26 0.00844 0.45 0.4534 1.0 1986838 ChemDiv2_005821 COc1ccccc1N2CCN(CC2)C(=O)C(CC(C)C)NC(=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I14 compound treatment 0.281 0.0294 1.58 1.5819 1.0 1986839 ChemDiv2_005822 Fc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc4c(=O)n(c5ccccc5)c(=O)[nH]c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I15 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986840 ChemDiv2_005823 CCC(C)NC(=O)C1CCCCN1S(=O)(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I16 compound treatment 0.339 0.0874 4.7 4.6987 1.0 1986841 ChemDiv2_005824 CCOc1ccc(cc1)n2c(=O)[nH]c3sc4CCCc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I17 compound treatment 0.261 0.00944 0.51 0.5072 1.0 1986842 ChemDiv2_005825 O=C(NC1CCCCC1)C(Cc2ccccc2)NS(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I18 compound treatment 0.487 0.235 12.65 12.6519 1.0 1986843 ChemDiv2_005826 C1Oc2ccc(cc2O1)c3cn4ccsc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I19 compound treatment 0.372 0.12 6.47 6.4721 1.0 1986844 ChemDiv2_005827 C1CN(CCO1)c2ccc(cc2)c3nc4cnccn4c3Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I20 compound treatment 0.251 -5.63E-4 -0.03 -0.0302 -1.0 1986845 ChemDiv2_005828 Cc1cccc(NC2=NC3CS(=O)(=O)CC3S2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I21 compound treatment 0.478 0.226 12.17 12.1683 1.0 1986846 ChemDiv2_005829 O=C(CCCCn1c(=O)[nH]c2ccsc2c1=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I22 compound treatment 0.242 -0.00956 -0.51 -0.5139 -1.0 1986847 ChemDiv2_005830 Cc1ccc2OCC(=O)N(CC(=O)NC3CCCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I23 mock treatment 0.252 4.37E-4 0.02 0.0235 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 I24 mock treatment 0.26 0.00844 0.45 0.4534 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J01 compound treatment 0.29 0.0384 2.07 2.0656 1.0 1986848 ChemDiv2_005831 CCOC(=O)C1=C(NC(=C(C#N)C1c2ccco2)SCC(=O)Nc3ccc(F)cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J02 compound treatment 0.486 0.234 12.6 12.5982 1.0 1986849 ChemDiv2_005832 Oc1cccc(NC(=O)c2cc(on2)c3ccc4OCOc4c3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J03 compound treatment 0.468 0.216 11.63 11.6309 1.0 1986850 ChemDiv2_005833 CC1(C)CC(=O)c2cc(OCC(=O)NC3CC3)ccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J04 compound treatment 0.482 0.23 12.38 12.3832 1.0 1986851 ChemDiv2_005834 COc1ccc(OC)c(c1)c2cc(no2)C(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J05 compound treatment 0.543 0.291 15.66 15.6612 1.0 1986852 ChemDiv2_005835 CCCCn1cnc2cc(NCc3cc(OC)ccc3OC)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J06 compound treatment 0.411 0.159 8.57 8.5678 1.0 1986853 ChemDiv2_005836 COCC(C)NC(=O)c1cc(on1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J07 compound treatment 0.313 0.0614 3.3 3.3015 1.0 1986854 ChemDiv2_005837 O=C1CC(c2ccccc2OCc3ccccc3)c4cc5OCCOc5cc4N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J08 compound treatment 0.365 0.113 6.1 6.0959 1.0 1986855 ChemDiv2_005838 CCc1ccccc1NC(=O)c2cc(on2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J09 compound treatment 0.595 0.343 18.46 18.4556 1.0 1338855 ChemDiv2_005839 O=c1[nH]c2ccc(cc2[nH]c1=O)S(=O)(=O)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J10 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986856 ChemDiv2_005840 CC1CCCC(C)N1C(=O)c2cc(C)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J11 compound treatment 0.286 0.0344 1.85 1.8506 1.0 1986857 ChemDiv2_005841 CCOc1ccc(NC(=O)C(NS(=O)(=O)c2cccs2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J12 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986858 ChemDiv2_005842 C=CCNC(=O)c1cc(on1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J13 compound treatment 0.342 0.0904 4.86 4.8599 1.0 1986859 ChemDiv2_005843 CN(C(=O)c1cc(on1)c2ccc(F)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J14 compound treatment 0.27 0.0184 0.99 0.9908 1.0 1986860 ChemDiv2_005844 CC(C)c1cc(no1)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J15 compound treatment 0.271 0.0194 1.04 1.0445 1.0 1986861 ChemDiv2_005845 CCc1ccccc1NC(=O)c2cc(on2)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J16 compound treatment 0.28 0.0284 1.53 1.5282 1.0 1986862 ChemDiv2_005846 CCCc1cc(no1)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J17 compound treatment 0.345 0.0934 5.02 5.0211 1.0 1986863 ChemDiv2_005847 CCN(CC)C(=O)c1cc(on1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J18 compound treatment 0.333 0.0814 4.38 4.3763 1.0 1986864 ChemDiv2_005848 CC(C)Cc1cc(no1)C(=O)Nc2cc(Br)ccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J19 compound treatment 0.418 0.166 8.94 8.944 1.0 1986865 ChemDiv2_005849 COc1ccc(cc1)c2cc(no2)C(=O)N3CCCCC3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J20 compound treatment 0.259 0.00744 0.4 0.3997 1.0 1986866 ChemDiv2_005850 CN(C(=O)c1noc2CCCCc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J21 compound treatment 0.345 0.0934 5.02 5.0211 1.0 1986867 ChemDiv2_005851 CCC1CCCCN1C(=O)c2cc(on2)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J22 compound treatment 0.285 0.0334 1.8 1.7969 1.0 1986868 ChemDiv2_005852 CC1CCCC(C)N1C(=O)c2noc-3c2CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J23 mock treatment 0.246 -0.00556 -0.3 -0.2989 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 J24 mock treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K01 compound treatment 0.242 -0.00956 -0.51 -0.5139 -1.0 1986869 ChemDiv2_005853 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K02 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986870 ChemDiv2_005854 COc1cc(cc(OC)c1OC)C(=O)NC(C)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K03 compound treatment 0.479 0.227 12.22 12.222 1.0 1986871 ChemDiv2_005855 Brc1cc2CCN(C(=O)C3CC3)c2c(c1)S(=O)(=O)N4CCN(CC4)C5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K04 compound treatment 0.248 -0.00356 -0.19 -0.1914 -1.0 1986872 ChemDiv2_005856 O=C(Nc1ccc(cc1)C(=O)NC2CCCC2)C3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K05 compound treatment 0.256 0.00444 0.24 0.2385 1.0 1986873 ChemDiv2_005857 CCCOC(=O)C1=C(C)NC2=C(C1c3ccc(C)s3)C(=O)C(C(C)C2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K06 compound treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1986874 ChemDiv2_005858 O=C(NC1CCCCC1)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K07 compound treatment 0.278 0.0264 1.42 1.4207 1.0 1462367 ChemDiv2_005859 COc1cccc(c1)n2c(SCC(=O)Nc3nccs3)nc4c5ccccc5[nH]c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K08 compound treatment 0.237 -0.0146 -0.78 -0.7826 -1.0 1986875 ChemDiv2_005860 CC1CCCC(C)N1C(=O)Cn2c(=O)sc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K09 compound treatment 0.267 0.0154 0.83 0.8296 1.0 1492701 ChemDiv2_005861 Cn1c(CNCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K10 compound treatment 0.363 0.111 5.99 5.9884 1.0 1986876 ChemDiv2_005862 CCN1CCN(CC1)C(=O)c2ccc3c(=O)n(CCc4ccccc4)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K11 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986877 ChemDiv2_005863 CCC1CCC(CC1)C(=O)NC(C(C)C)C(=O)Nc2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K12 compound treatment 0.246 -0.00556 -0.3 -0.2989 -1.0 1986878 ChemDiv2_005864 OC(=O)c1[nH]c2ccccc2c1CC(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K13 compound treatment 0.233 -0.0186 -1.0 -0.9975 -1.0 1986879 ChemDiv2_005865 CC(C)C(NC(=O)C1CCC(C)CC1)C(=O)Nc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K14 compound treatment 0.506 0.254 13.67 13.6729 1.0 1986880 ChemDiv2_005866 C=CCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)N3CCC(=CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K15 compound treatment 0.252 4.37E-4 0.02 0.0235 1.0 1986881 ChemDiv2_005867 Fc1ccc(cc1)S(=O)(=O)N2CCCCC2C(=O)NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K16 compound treatment 0.267 0.0154 0.83 0.8296 1.0 1986882 ChemDiv2_005868 COc1ccc(cc1OC)n2c(=O)[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K17 compound treatment 0.308 0.0564 3.03 3.0328 1.0 1986883 ChemDiv2_005869 COc1ccc(NC(=O)C(Cc2ccccc2)NS(=O)(=O)c3cccs3)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K18 compound treatment 0.252 4.37E-4 0.02 0.0235 1.0 1986884 ChemDiv2_005870 COC(=O)c1cccnc1n2c(=O)[nH]c3ncccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K19 compound treatment 0.391 0.139 7.49 7.4931 1.0 1986885 ChemDiv2_005871 Oc1cccc(c1)c2nc3cnccn3c2Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K20 compound treatment 0.271 0.0194 1.04 1.0445 1.0 1986886 ChemDiv2_005872 COc1ccc(cc1OC)C(=O)C2=C(O)c3ccccc3S(=O)(=O)N2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K21 compound treatment 0.377 0.125 6.74 6.7407 1.0 1986887 ChemDiv2_005873 O=C(CCCn1c(=O)[nH]c2ccsc2c1=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K22 compound treatment 0.272 0.0204 1.1 1.0983 1.0 1986888 ChemDiv2_005874 CC(N1C(=O)COc2ccc(C)cc12)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K23 mock treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 K24 mock treatment 0.265 0.0134 0.72 0.7221 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L01 compound treatment 0.266 0.0144 0.78 0.7758 1.0 1986889 ChemDiv2_005875 CN(Cc1ccco1)S(=O)(=O)c2ccc3[nH]cc(C(=O)O)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L02 compound treatment 0.264 0.0124 0.67 0.6684 1.0 1986890 ChemDiv2_005876 Cc1cc(NC(=O)c2cc(on2)c3ccc4OCOc4c3)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L03 compound treatment 0.466 0.214 11.52 11.5234 1.0 1986891 ChemDiv2_005877 CC1CCCCC1NC(=O)COc2ccc3OC(C)(C)CC(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L04 compound treatment 0.402 0.15 8.08 8.0842 1.0 1986892 ChemDiv2_005878 O=C(NC1CCCC1)c2cc(on2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L05 compound treatment 0.506 0.254 13.67 13.6729 1.0 1986893 ChemDiv2_005879 CCCCn1cnc2cc(NCc3cccc(OC)c3OC)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L06 compound treatment 0.351 0.0994 5.34 5.3436 1.0 1986894 ChemDiv2_005880 CCN(CC)C(=O)c1cc(on1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L07 compound treatment 0.333 0.0814 4.38 4.3763 1.0 1986895 ChemDiv2_005881 CCN1CCN(CC1)C(=O)c2cnn3c(O)c(Cc4cccc(C)c4)c(C)nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L08 compound treatment 0.536 0.284 15.29 15.2851 1.0 1986896 ChemDiv2_005882 Clc1ccc(cc1Cl)c2cc(no2)C(=O)NCCCn3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L09 compound treatment 0.354 0.102 5.5 5.5048 1.0 1382036 ChemDiv2_005883 O=c1[nH]c2ccc(cc2[nH]c1=O)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L10 compound treatment 0.272 0.0204 1.1 1.0983 1.0 1986897 ChemDiv2_005884 Cc1cc(no1)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L11 compound treatment 0.547 0.295 15.88 15.8762 1.0 1986898 ChemDiv2_005885 O=C(CCS(=O)(=O)c1cccs1)Nc2ccc(cc2)C(=O)N3CCC(=CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L12 compound treatment 0.277 0.0254 1.37 1.367 1.0 1986899 ChemDiv2_005886 CCc1ccccc1NC(=O)c2cc(on2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L13 compound treatment 0.34 0.0884 4.75 4.7524 1.0 1986900 ChemDiv2_005887 Fc1ccc(cc1)c2cc(no2)C(=O)Nc3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L14 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986901 ChemDiv2_005888 CC(C)c1cc(no1)C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L15 compound treatment 0.428 0.176 9.48 9.4814 1.0 1986902 ChemDiv2_005889 Oc1ccc(cc1)c2cc(no2)C(=O)NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L16 compound treatment 0.465 0.213 11.47 11.4697 1.0 1986903 ChemDiv2_005890 CCCc1cc(no1)C(=O)Nc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L17 compound treatment 0.42 0.168 9.05 9.0515 1.0 1986904 ChemDiv2_005891 Oc1ccc(cc1)c2cc(no2)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L18 compound treatment 0.383 0.131 7.06 7.0632 1.0 1986905 ChemDiv2_005892 CC(C)Cc1cc(no1)C(=O)Nc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L19 compound treatment 0.483 0.231 12.44 12.437 1.0 1986906 ChemDiv2_005893 COc1ccc(cc1)c2cc(no2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L20 compound treatment 0.47 0.218 11.74 11.7384 1.0 1986907 ChemDiv2_005894 Oc1cccc(NC(=O)c2noc3CCCCc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L21 compound treatment 0.267 0.0154 0.83 0.8296 1.0 1986908 ChemDiv2_005895 COc1ccccc1c2cc(no2)C(=O)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L22 compound treatment 0.27 0.0184 0.99 0.9908 1.0 1986909 ChemDiv2_005896 O=C(N1CCCC1)c2noc-3c2CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L23 mock treatment 0.243 -0.00856 -0.46 -0.4601 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 L24 mock treatment 0.247 -0.00456 -0.25 -0.2452 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M01 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986910 ChemDiv2_005897 CCC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M02 compound treatment 0.249 -0.00256 -0.14 -0.1377 -1.0 1986911 ChemDiv2_005898 CC(=O)NCCc1nc2ccccc2n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M03 compound treatment 0.243 -0.00856 -0.46 -0.4601 -1.0 1986912 ChemDiv2_005899 Brc1cc2CCN(C(=O)C3CC3)c2c(c1)S(=O)(=O)NCCCN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M04 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1986913 ChemDiv2_005900 CCOC(=O)C1CCN(CC1)C(=O)c2ccc(NC(=O)C3CCCO3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M05 compound treatment 0.257 0.00544 0.29 0.2922 1.0 1986914 ChemDiv2_005901 O=C(CSc1nc2CCSc2c(=O)n1c3ccccc3)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M06 compound treatment 0.394 0.142 7.65 7.6543 1.0 1986915 ChemDiv2_005902 CN(Cc1ccccc1)C(=O)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M07 compound treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1445957 ChemDiv2_005903 COc1ccc(cc1)n2c(SCC(=O)N3CCCCC3)nc4c5ccccc5[nH]c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M08 compound treatment 0.377 0.125 6.74 6.7407 1.0 1986916 ChemDiv2_005904 O=C(CS(=O)(=O)c1c[nH]c2ccccc12)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M09 compound treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1674641 ChemDiv2_005905 Cn1c(CNC2CCCCC2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M10 compound treatment 0.472 0.22 11.85 11.8459 1.0 1986917 ChemDiv2_005906 NS(=O)(=O)c1ccc(CCNC(=O)CCCn2c(=O)[nH]c3ccc(Br)cc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M11 compound treatment 0.243 -0.00856 -0.46 -0.4601 -1.0 1986918 ChemDiv2_005907 CCC1CCC(CC1)C(=O)NC(C(C)C)C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M12 compound treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1986919 ChemDiv2_005908 OC(=O)c1[nH]c2ccccc2c1CC(=O)NCCCN3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M13 compound treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1986920 ChemDiv2_005909 CCN1CCN(CC1)C(=O)C(NC(=O)C2CCC(C)CC2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M14 compound treatment 0.389 0.137 7.39 7.3856 1.0 1986921 ChemDiv2_005910 Cc1ccc(NC(=O)c2c(C)nc3sc(C(=O)N4CCCC4)c(N)c3c2c5ccco5)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M15 compound treatment 0.271 0.0194 1.04 1.0445 1.0 1986922 ChemDiv2_005911 CC(C)C(=O)NCCSc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M16 compound treatment 0.249 -0.00256 -0.14 -0.1377 -1.0 1986923 ChemDiv2_005912 COc1cc2n(CC(=O)N3CC(C)CC(C)C3)c(=O)n(Cc4ccccc4)c(=O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M17 compound treatment 0.342 0.0904 4.86 4.8599 1.0 1986924 ChemDiv2_005913 CCOc1ccccc1NC(=O)C(Cc2ccccc2)NS(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M18 compound treatment 0.259 0.00744 0.4 0.3997 1.0 1986925 ChemDiv2_005914 CCN(CC)C(=O)c1sc2[nH]c(=O)n(c3ccccc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M19 compound treatment 0.276 0.0244 1.31 1.3132 1.0 1986926 ChemDiv2_005915 Clc1ccc(Nc2c(nc3cnccn23)c4ccccn4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M20 compound treatment 0.305 0.0534 2.87 2.8716 1.0 1986927 ChemDiv2_005916 CCOC(=O)c1cn(CC(=O)N(Cc2ccccc2)c3ccc(Br)cc3)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M21 compound treatment 0.509 0.257 13.83 13.8342 1.0 1986928 ChemDiv2_005917 NS(=O)(=O)c1ccc(CCNC(=O)CCc2nc3sc4CCCCc4c3c(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M22 compound treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1229673 ChemDiv2_005918 CNS(=O)(=O)c1cccc2nsnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M23 mock treatment 0.244 -0.00756 -0.41 -0.4064 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 M24 mock treatment 0.252 4.37E-4 0.02 0.0235 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N01 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986929 ChemDiv2_005919 COc1ccc(CNS(=O)(=O)c2ccc3[nH]cc(C(=O)O)c(=O)c3c2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N02 compound treatment 0.332 0.0804 4.32 4.3225 1.0 1986930 ChemDiv2_005920 Cc1ccccc1Cn2cc(NC(=O)c3cc(on3)c4ccc5OCOc5c4)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N03 compound treatment 0.342 0.0904 4.86 4.8599 1.0 1986931 ChemDiv2_005921 CCN1CCN(CCCNC(=O)COc2ccc3OC(C)(C)CC(=O)c3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N04 compound treatment 0.359 0.107 5.77 5.7735 1.0 1986932 ChemDiv2_005922 O=C(N1CCCc2ccccc12)c3cc(on3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N05 compound treatment 0.525 0.273 14.69 14.694 1.0 1986933 ChemDiv2_005923 CCCCn1cnc2cc(NCc3cc(OC)c(OC)c(OC)c3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N06 compound treatment 0.373 0.121 6.53 6.5258 1.0 1986934 ChemDiv2_005924 C=CCNC(=O)c1cc(on1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N07 compound treatment 0.466 0.214 11.52 11.5234 1.0 1986935 ChemDiv2_005925 Cc1nc2c(cnn2c(O)c1Cc3ccc(Cl)cc3)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N08 compound treatment 0.492 0.24 12.92 12.9206 1.0 1986936 ChemDiv2_005926 CN(Cc1ccccc1)C(=O)c2cc(on2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N09 compound treatment 0.444 0.192 10.34 10.3412 1.0 1299726 ChemDiv2_005927 O=c1[nH]c2ccc(cc2[nH]c1=O)S(=O)(=O)Nc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N10 compound treatment 0.311 0.0594 3.19 3.194 1.0 1986937 ChemDiv2_005928 Cc1cc(no1)C(=O)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N11 compound treatment 0.411 0.159 8.57 8.5678 1.0 1986938 ChemDiv2_005929 O=C(CCS(=O)(=O)c1cccs1)Nc2ccc(cc2)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N12 compound treatment 0.35 0.0984 5.29 5.2898 1.0 1986939 ChemDiv2_005930 COC(=O)c1ccccc1NC(=O)c2cc(on2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N13 compound treatment 0.291 0.0394 2.12 2.1193 1.0 1986940 ChemDiv2_005931 Cc1ccc(Cn2ccc(NC(=O)c3cc(on3)c4ccc(F)cc4)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N14 compound treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1986941 ChemDiv2_005932 CCC(C)NC(=O)c1cc(on1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N15 compound treatment 0.445 0.193 10.39 10.3949 1.0 1986942 ChemDiv2_005933 Oc1ccc(cc1)c2cc(no2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N16 compound treatment 0.365 0.113 6.1 6.0959 1.0 1986943 ChemDiv2_005934 CCCc1cc(no1)C(=O)Nc2ccccc2C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N17 compound treatment 0.397 0.145 7.82 7.8155 1.0 1986944 ChemDiv2_005935 Oc1ccc(cc1)c2cc(no2)C(=O)Nc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N18 compound treatment 0.291 0.0394 2.12 2.1193 1.0 1986945 ChemDiv2_005936 CC(C)Cc1cc(no1)C(=O)Nc2cnn(Cc3ccc(F)cc3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N19 compound treatment 0.286 0.0344 1.85 1.8506 1.0 1986946 ChemDiv2_005937 COc1ccc(cc1)c2cc(no2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N20 compound treatment 0.254 0.00244 0.13 0.131 1.0 1986947 ChemDiv2_005938 Cc1ccc(NC(=O)c2noc3CCCCc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N21 compound treatment 0.308 0.0564 3.03 3.0328 1.0 1986948 ChemDiv2_005939 COc1ccc(cc1OC)c2cc(no2)C(=O)N(C)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N22 compound treatment 0.252 4.37E-4 0.02 0.0235 1.0 1986949 ChemDiv2_005940 CN(C(=O)c1noc-2c1CCc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N23 mock treatment 0.242 -0.00956 -0.51 -0.5139 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 N24 mock treatment 0.245 -0.00656 -0.35 -0.3527 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O01 compound treatment 0.336 0.0844 4.54 4.5375 1.0 1986950 ChemDiv2_005941 COc1ccccc1CNC(=O)CCS(=O)(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O02 compound treatment 0.44 0.188 10.13 10.1262 1.0 1986951 ChemDiv2_005942 CCn1c(CCNC(=O)c2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O03 compound treatment 0.387 0.135 7.28 7.2781 1.0 1986952 ChemDiv2_005943 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2cc(Br)cc3CC(C)N(C(=O)C)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O04 compound treatment 0.24 -0.0116 -0.62 -0.6213 -1.0 1986953 ChemDiv2_005944 CC1CCN(CC1)C(=O)c2ccc(NC(=O)C3CCCO3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O05 compound treatment 0.24 -0.0116 -0.62 -0.6213 -1.0 1986954 ChemDiv2_005945 CSc1nc2CCSc2c(=O)n1c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O06 compound treatment 0.273 0.0214 1.15 1.152 1.0 1986955 ChemDiv2_005946 CC1CCCCN1C(=O)c2cc3c(=O)oc4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O07 compound treatment 0.238 -0.0136 -0.73 -0.7288 -1.0 1145579 ChemDiv2_005947 COc1ccc(cc1)n2c(SCC(=O)NCC3CCCO3)nc4c5ccccc5[nH]c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O08 compound treatment 0.27 0.0184 0.99 0.9908 1.0 1986956 ChemDiv2_005948 COCCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O09 compound treatment 0.397 0.145 7.82 7.8155 1.0 1986957 ChemDiv2_005949 C(Cn1c(CNc2ccccc2)nc3ccccc13)Oc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O10 compound treatment 0.436 0.184 9.91 9.9113 1.0 1986958 ChemDiv2_005950 COc1cc2[nH]c(=O)n(CCCC(=O)N3CCN(CC3)c4cc(Cl)ccc4C)c(=O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O11 compound treatment 0.239 -0.0126 -0.68 -0.6751 -1.0 1986959 ChemDiv2_005951 CC(C)C(NC(=O)C1CCC(C)CC1)C(=O)NC2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O12 compound treatment 0.257 0.00544 0.29 0.2922 1.0 1986960 ChemDiv2_005952 OC(=O)c1[nH]c2ccccc2c1CC(=O)N(CC=C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O13 compound treatment 0.256 0.00444 0.24 0.2385 1.0 1986961 ChemDiv2_005953 CC(C)CC(NC(=O)C1CCC(C)CC1)C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O14 compound treatment 0.252 4.37E-4 0.02 0.0235 1.0 1986962 ChemDiv2_005954 COc1ccc(c(OC)c1)n2c(=O)n(Cc3ccccc3C#N)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O15 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986963 ChemDiv2_005955 Nc1n[nH]c2nc(nc(c3ccccc3)c12)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O16 compound treatment 0.467 0.215 11.58 11.5772 1.0 1986964 ChemDiv2_005956 CSc1cccc(c1)n2cc([nH]c2=O)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O17 compound treatment 0.409 0.157 8.46 8.4604 1.0 1986965 ChemDiv2_005957 CCOc1ccc2nc(NC(=O)c3ccc(NS(=O)(=O)c4cccs4)cc3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O18 compound treatment 0.256 0.00444 0.24 0.2385 1.0 1986966 ChemDiv2_005958 CCOc1ccc(NC2=NC3CS(=O)(=O)CC3S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O19 compound treatment 0.26 0.00844 0.45 0.4534 1.0 1986967 ChemDiv2_005959 COc1ccc(Nc2c(nc3cnccn23)c4ccsc4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O20 compound treatment 0.265 0.0134 0.72 0.7221 1.0 1986968 ChemDiv2_005960 N/C(=N\O)/c1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O21 compound treatment 0.322 0.0704 3.79 3.7852 1.0 1986969 ChemDiv2_005961 COc1ccc(CCNC(=O)CCc2nc3sc4CCCCc4c3c(=O)[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O22 compound treatment 0.252 4.37E-4 0.02 0.0235 1.0 1986970 ChemDiv2_005962 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N(CC=C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O23 mock treatment 0.251 -5.63E-4 -0.03 -0.0302 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 O24 mock treatment 0.267 0.0154 0.83 0.8296 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P01 compound treatment 0.263 0.0114 0.61 0.6146 1.0 1986971 ChemDiv2_005963 CC(=O)N1CCC2(CC1)CC(=O)c3cc(OCC(=O)NCc4ccccc4)ccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P02 compound treatment 0.297 0.0454 2.44 2.4417 1.0 1986972 ChemDiv2_005964 Fc1ccc(Cn2cc(NC(=O)c3cc(on3)c4ccc5OCOc5c4)cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P03 compound treatment 0.454 0.202 10.88 10.8786 1.0 1986973 ChemDiv2_005965 CC1(C)CC(=O)c2cc(OCC(=O)NCCCN3CCN(CC3)c4ccccc4F)ccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P04 compound treatment 0.481 0.229 12.33 12.3295 1.0 1986974 ChemDiv2_005966 O=C(N1CCCC1)c2cc(on2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P05 compound treatment 0.41 0.158 8.51 8.5141 1.0 1986975 ChemDiv2_005967 Cn1cnc2cc(NCc3ccncc3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P06 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986976 ChemDiv2_005968 COC(=O)c1ccccc1NC(=O)c2cc(on2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P07 compound treatment 0.254 0.00244 0.13 0.131 1.0 1986977 ChemDiv2_005969 CC(C)C(NS(=O)(=O)c1cccs1)C(=O)N(C)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P08 compound treatment 0.263 0.0114 0.61 0.6146 1.0 1986978 ChemDiv2_005970 CC1CCCCN1C(=O)c2cc(on2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P09 compound treatment 0.436 0.184 9.91 9.9113 1.0 1986979 ChemDiv2_005971 O=c1[nH]c2ccc(cc2[nH]c1=O)S(=O)(=O)N(CCc3ccccc3)Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P10 compound treatment 0.242 -0.00956 -0.51 -0.5139 -1.0 1986980 ChemDiv2_005972 CCc1c(C)sc(NC(=O)c2cc(C)on2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P11 compound treatment 0.279 0.0274 1.47 1.4744 1.0 1986981 ChemDiv2_005973 CN1CCN(CC1)C(=O)c2cc(on2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P12 compound treatment 0.36 0.108 5.83 5.8272 1.0 1986982 ChemDiv2_005974 Oc1cccc(NC(=O)c2cc(on2)C3CC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P13 compound treatment 0.286 0.0344 1.85 1.8506 1.0 1986983 ChemDiv2_005975 Clc1ccc(cc1)c2cc(no2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P14 compound treatment 0.374 0.122 6.58 6.5795 1.0 1986984 ChemDiv2_005976 COc1ccc(CCNC(=O)c2cc(on2)C(C)C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P15 compound treatment 0.404 0.152 8.19 8.1917 1.0 1986985 ChemDiv2_005977 Oc1ccc(cc1)c2cc(no2)C(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P16 compound treatment 0.353 0.101 5.45 5.451 1.0 1986986 ChemDiv2_005978 CCCc1cc(no1)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P17 compound treatment 0.356 0.104 5.61 5.6123 1.0 1986987 ChemDiv2_005979 Cc1ccc(NC(=O)c2cc(on2)c3ccc(O)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P18 compound treatment 0.284 0.0324 1.74 1.7431 1.0 1986988 ChemDiv2_005980 Clc1cccc(NC(=O)c2noc3CCCc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P19 compound treatment 0.287 0.0354 1.9 1.9043 1.0 1986989 ChemDiv2_005981 COc1ccc(cc1)c2cc(no2)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P20 compound treatment 0.331 0.0794 4.27 4.2688 1.0 1986990 ChemDiv2_005982 Fc1ccc(Cn2cc(NC(=O)c3noc4CCCCc34)cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P21 compound treatment 0.253 0.00144 0.08 0.0772 1.0 1986991 ChemDiv2_005983 COc1ccc(cc1OC)c2cc(no2)C(=O)Nc3sc4CC(C)CCc4c3C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P22 compound treatment 0.258 0.00644 0.35 0.3459 1.0 1986992 ChemDiv2_005984 Cc1ccc(NC(=O)c2noc-3c2CCc4ccccc34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P23 mock treatment 0.251 -5.63E-4 -0.03 -0.0302 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1385 P24 mock treatment 0.25 -0.00156 -0.08 -0.084 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A01 compound treatment 0.242 0.00161 0.09 0.0867 1.0 1986993 ChemDiv2_005985 COc1ccc2-c3onc(C(=O)NCc4ccccc4)c3CCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A02 compound treatment 0.234 -0.00639 -0.34 -0.3432 -1.0 1986994 ChemDiv2_005986 CCOC(=O)c1ccccc1NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A03 compound treatment 0.323 0.0826 4.44 4.4394 1.0 1986995 ChemDiv2_005987 CCCCN(C)C(=O)C1C2N(CCc3ccccc23)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A04 compound treatment 0.223 -0.0174 -0.93 -0.9343 -1.0 1986996 ChemDiv2_005988 Cc1ccccc1NC(=O)Cn2c(=O)n(C3CCCC3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A05 compound treatment 0.229 -0.0114 -0.61 -0.6119 -1.0 1986997 ChemDiv2_005989 Cc1ccc(NC(=O)Cn2c(=O)n(c3cc(C)cc(C)c3)c(=O)c4sccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A06 compound treatment 0.24 -3.87E-4 -0.02 -0.0208 -1.0 1986998 ChemDiv2_005990 O=C(Cc1ccc(cc1)n2c(=O)n(CC(=O)NCc3ccco3)c4ccccc4c2=O)NCC5CCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A07 compound treatment 0.236 -0.00439 -0.24 -0.2358 -1.0 1986999 ChemDiv2_005991 CCC(C)NC(=O)Cn1c(=O)n(CC(=O)NCCc2ccccc2)c(=O)c3sccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A08 compound treatment 0.232 -0.00839 -0.45 -0.4507 -1.0 1987000 ChemDiv2_005992 CCOc1ccc(NC(=O)Cn2c(=O)n(CC(=O)NC3CCCC3)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A09 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987001 ChemDiv2_005993 COC(=O)CSc1nnc(CNC(=O)Cc2ccccc2)n1c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A10 compound treatment 0.241 6.13E-4 0.03 0.0329 1.0 1987002 ChemDiv2_005994 COc1cccc(CNC(=O)C2C3N(CCc4cc(OC)c(OC)cc34)C(=O)c5ccccc25)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A11 compound treatment 0.238 -0.00239 -0.13 -0.1283 -1.0 1987003 ChemDiv2_005995 CC1(CCC(=O)N1Cc2ccccc2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A12 compound treatment 0.233 -0.00739 -0.4 -0.397 -1.0 1987004 ChemDiv2_005996 CN1C(C(C(=O)NC2CC2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A13 compound treatment 0.235 -0.00539 -0.29 -0.2895 -1.0 1987005 ChemDiv2_005997 CCN(Cc1ccccc1)C(=O)C2(CC2)S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A14 compound treatment 0.233 -0.00739 -0.4 -0.397 -1.0 1987006 ChemDiv2_005998 CCOc1ccccc1C2CC(=O)NC3=C2C(=O)CCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A15 compound treatment 0.238 -0.00239 -0.13 -0.1283 -1.0 1987007 ChemDiv2_005999 CCC(C)NC(=O)C1N(Cc2ccc(F)cc2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A16 compound treatment 0.244 0.00361 0.19 0.1941 1.0 1987008 ChemDiv2_006000 Fc1ccc(cc1)C2CC(=O)C3=C(C2)NC(=O)CC3c4cccc(F)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A17 compound treatment 0.226 -0.0144 -0.77 -0.7731 -1.0 1987009 ChemDiv2_006001 O=C(Cn1c(=O)n(c2ccccc2)c(=O)c3c4CCCc4sc13)NCc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A18 compound treatment 0.391 0.151 8.09 8.0936 1.0 1987010 ChemDiv2_006002 CCn1c(SCC(=O)Nc2ccccc2)nc3CC(C)Sc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A19 compound treatment 0.383 0.143 7.66 7.6637 1.0 1987011 ChemDiv2_006003 CN(CC(=O)Nc1nc2c(C)cccc2s1)S(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A20 compound treatment 0.23 -0.0104 -0.56 -0.5582 -1.0 1987012 ChemDiv2_006004 COC(=O)c1c2CCCc2nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A21 compound treatment 0.221 -0.0194 -1.04 -1.0418 -1.0 1987013 ChemDiv2_006005 Clc1ccc2c(=O)n(Cc3cccs3)c(=O)n(CC(=O)NCC4CCCO4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A22 compound treatment 0.269 0.0286 1.54 1.5376 1.0 1987014 ChemDiv2_006006 CCOc1cc2CCN3C(C(C(=O)NCCCN4CCN(C)CC4)c5ccccc5C3=O)c2cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A23 mock treatment 0.226 -0.0144 -0.77 -0.7731 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 A24 mock treatment 0.245 0.00461 0.25 0.2479 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B01 compound treatment 0.312 0.0716 3.85 3.8483 1.0 1987015 ChemDiv2_006007 Cc1ccc(cc1)c2noc(CCC(=O)N3CCCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B02 compound treatment 0.53 0.29 15.56 15.5632 1.0 1987016 ChemDiv2_006008 COc1ccc2nc3sc(cc3cc2c1)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B03 compound treatment 0.257 0.0166 0.89 0.8927 1.0 1987017 ChemDiv2_006009 Cc1ccc(CNC(=O)CCc2nc(no2)c3ccc(C)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B04 compound treatment 0.462 0.222 11.91 11.909 1.0 1987018 ChemDiv2_006010 CCCC1=Nc2cc(ccc2Sc3ccccc13)C(=O)N4CCC(CC4)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B05 compound treatment 0.377 0.137 7.34 7.3413 1.0 1987019 ChemDiv2_006011 CC(CCc1ccccc1)NC(=O)CCc2nc(no2)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B06 compound treatment 0.268 0.0276 1.48 1.4839 1.0 1987020 ChemDiv2_006012 Cn1cc(CC(=O)NC2CCCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B07 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987021 ChemDiv2_006013 COCCN1C(C(C(=O)NCc2ccccn2)c3ccccc3C1=O)c4cn(C)c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B08 compound treatment 0.517 0.277 14.86 14.8646 1.0 1987022 ChemDiv2_006014 COCCn1c(=NC(=O)CSCC(=O)NC2CCCCC2)sc3cc(OC)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B09 compound treatment 0.406 0.166 8.9 8.8997 1.0 1987023 ChemDiv2_006015 Fc1ccc(F)c(NC(=O)CCS(=O)(=O)c2cc(Br)cc3CCN(C(=O)C4CC4)c32)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B10 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987024 ChemDiv2_006016 Cc1noc(C)c1S(=O)(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B11 compound treatment 0.278 0.0376 2.02 2.0212 1.0 1987025 ChemDiv2_006017 CCOc1ccc(CCNc2cc(C)nc3ncnn23)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B12 compound treatment 0.363 0.123 6.59 6.589 1.0 1987026 ChemDiv2_006018 Cc1ccc(o1)c2nc3ncccn3c2NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B13 compound treatment 0.241 6.13E-4 0.03 0.0329 1.0 1987027 ChemDiv2_006019 COc1cc(OC)c(Nc2nc3ccccc3n4cnnc24)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B14 compound treatment 0.274 0.0336 1.81 1.8063 1.0 1987028 ChemDiv2_006020 COC(=O)c1nnn(CC(=O)N(c2ccccc2)c3ccccc3)c1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B15 compound treatment 0.299 0.0586 3.15 3.1497 1.0 1987029 ChemDiv2_006021 COc1cccc(CNc2nc3ccc(C)cc3n4cnnc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B16 compound treatment 0.24 -3.87E-4 -0.02 -0.0208 -1.0 1987030 ChemDiv2_006022 Cc1ccc2ncc3c(n[nH]c3c2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B17 compound treatment 0.538 0.298 15.99 15.9931 1.0 1987031 ChemDiv2_006023 O=C(CCc1nc2ccccc2[nH]1)Nc3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B18 compound treatment 0.285 0.0446 2.4 2.3974 1.0 1987032 ChemDiv2_006024 CN(C(=O)Cn1cccc1C2=NC(CO2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B19 compound treatment 0.266 0.0256 1.38 1.3764 1.0 1987033 ChemDiv2_006025 Clc1ccc(Cc2nnc(o2)C(=O)NCc3ccc4OCOc4c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B20 compound treatment 0.241 6.13E-4 0.03 0.0329 1.0 1987034 ChemDiv2_006026 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B21 compound treatment 0.239 -0.00139 -0.07 -0.0745 -1.0 1987035 ChemDiv2_006027 Cc1ccc(CNC(=O)c2nnc(Cc3ccc(F)cc3)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B22 compound treatment 0.232 -0.00839 -0.45 -0.4507 -1.0 1987036 ChemDiv2_006028 Cc1ccc2cc3cc(oc3nc2c1)C(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B23 mock treatment 0.245 0.00461 0.25 0.2479 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 B24 mock treatment 0.224 -0.0164 -0.88 -0.8806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C01 compound treatment 0.32 0.0796 4.28 4.2782 1.0 1987037 ChemDiv2_006029 Cc1cc(nc2ccc(NC(=O)CCC(=O)NCc3ccco3)cc12)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C02 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987038 ChemDiv2_006030 CCN(C(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C03 compound treatment 0.252 0.0116 0.62 0.6241 1.0 1987039 ChemDiv2_006031 CCN(CC)C(=O)C1C2N(CCc3ccccc23)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C04 compound treatment 0.326 0.0856 4.6 4.6007 1.0 1987040 ChemDiv2_006032 Clc1ccc(Cn2c(=O)n(CCCC(=O)NC3CCCC3)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C05 compound treatment 0.275 0.0346 1.86 1.86 1.0 1987041 ChemDiv2_006033 CC1CCCCN1C(=O)Cn2c(=O)n(CCCC(=O)NCc3ccc(C)cc3)c(=O)c4sccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C06 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987042 ChemDiv2_006034 Cc1cc(NC(=O)Cn2c(=O)n(CCCC(=O)NCc3ccccc3Cl)c(=O)c4ccccc24)[nH]n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C07 compound treatment 0.311 0.0706 3.79 3.7946 1.0 1987043 ChemDiv2_006035 O=C(Cn1c(=O)n(CC(=O)Nc2ccccc2)c3ccsc3c1=O)NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C08 compound treatment 0.32 0.0796 4.28 4.2782 1.0 1987044 ChemDiv2_006036 COc1cccc(NC(=O)Cn2c(=O)n(CC(=O)NCCc3ccccc3)c(=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C09 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987045 ChemDiv2_006037 CCCCn1c(CNC(=O)c2ccccc2F)nnc1SCC(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C10 compound treatment 0.438 0.198 10.62 10.6193 1.0 1370963 ChemDiv2_006038 CCOc1ccc(Cc2nnc(N)s2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C11 compound treatment 0.279 0.0386 2.07 2.075 1.0 1987046 ChemDiv2_006039 CC1(CCC(=O)N1CCc2ccc(Cl)cc2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C12 compound treatment 0.253 0.0126 0.68 0.6778 1.0 1987047 ChemDiv2_006040 Fc1ccc(cc1)N2COc3cc4OCOc4cc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C13 compound treatment 0.3 0.0596 3.2 3.2035 1.0 1276472 ChemDiv2_006041 Clc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C14 compound treatment 0.252 0.0116 0.62 0.6241 1.0 1987048 ChemDiv2_006042 Brc1cccc(c1)C2CC(=O)NC3=C2C(=O)CCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C15 compound treatment 0.242 0.00161 0.09 0.0867 1.0 1987049 ChemDiv2_006043 CCC(C)NC(=O)C1N(C(C)CCc2ccccc2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C16 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987050 ChemDiv2_006044 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=O)CC3c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C17 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987051 ChemDiv2_006045 CC1CCCCN1C(=O)Cn2c(=O)n(c3ccccc3)c(=O)c4c5CCCc5sc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C18 compound treatment 0.318 0.0776 4.17 4.1708 1.0 1987052 ChemDiv2_006046 COCCn1c(SCC(=O)N2CCCc3ccccc23)nc4CC(C)Sc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C19 compound treatment 0.274 0.0336 1.81 1.8063 1.0 1987053 ChemDiv2_006047 CCC(C)NC(=O)C1CCN(CC1)S(=O)(=O)c2cccc3nonc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C20 compound treatment 0.447 0.207 11.1 11.1029 1.0 1987054 ChemDiv2_006048 CCCOc1ccc2oc(=O)c3N(CCCc3c2c1)C(=O)CN(C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C21 compound treatment 0.292 0.0516 2.77 2.7736 1.0 1987055 ChemDiv2_006049 Fc1ccc(CNC(=O)CCCn2c(=O)n(Cc3ccc(F)cc3)c4ccccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C22 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987056 ChemDiv2_006050 CCCCN(CC)C(=O)Cc1c([nH]c2ccc(Cl)cc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C23 mock treatment 0.253 0.0126 0.68 0.6778 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 C24 mock treatment 0.241 6.13E-4 0.03 0.0329 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D01 compound treatment 0.432 0.192 10.3 10.2969 1.0 1987057 ChemDiv2_006051 CCN(Cc1ccccc1)C(=O)CCc2nc(no2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D02 compound treatment 0.557 0.317 17.01 17.0141 1.0 1987058 ChemDiv2_006052 CC1=Nc2cc(ccc2Sc3ccccc13)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D03 compound treatment 0.315 0.0746 4.01 4.0095 1.0 1987059 ChemDiv2_006053 COc1ccc2nc(NC(=O)CCc3nc(no3)c4ccccc4F)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D04 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987060 ChemDiv2_006054 COc1ccccc1NC(=O)C2=C(C)Nc3nc(SC)nn3C2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D05 compound treatment 0.467 0.227 12.18 12.1777 1.0 1987061 ChemDiv2_006055 COc1ccc(Br)cc1CNC(=O)CCc2nc(no2)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D06 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987062 ChemDiv2_006056 Cn1cc(CC(=O)NCC2CCCO2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D07 compound treatment 0.24 -3.87E-4 -0.02 -0.0208 -1.0 1987063 ChemDiv2_006057 COc1cccc(C(N2CCCC(C)C2)c3c(O)[nH]c(=O)[nH]c3=O)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D08 compound treatment 0.531 0.291 15.62 15.6169 1.0 1987064 ChemDiv2_006058 COCCn1c(=NC(=O)CSCC(=O)N2CCc3ccccc23)sc4cc(OC)ccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D09 compound treatment 0.439 0.199 10.67 10.673 1.0 1987065 ChemDiv2_006059 COc1ccc(NC(=O)CCS(=O)(=O)c2cc(Br)cc3CCN(C(=O)C4CC4)c32)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D10 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987066 ChemDiv2_006060 Cc1noc(C)c1S(=O)(=O)NCc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D11 compound treatment 0.293 0.0526 2.83 2.8273 1.0 1987067 ChemDiv2_006061 Cc1cc(N2CC(=O)N(CCc3ccccc3)C(=O)C2)n4ncnc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D12 compound treatment 0.349 0.109 5.84 5.8366 1.0 1987068 ChemDiv2_006062 COc1cc(ccc1O)c2nc3ncccn3c2Nc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D13 compound treatment 0.318 0.0776 4.17 4.1708 1.0 1987069 ChemDiv2_006063 COc1ccc(OC)c(Nc2nc3ccccc3n4cnnc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D14 compound treatment 0.267 0.0266 1.43 1.4301 1.0 1987070 ChemDiv2_006064 COC(=O)c1nnn(CC(=O)Nc2ccc3OCOc3c2)c1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D15 compound treatment 0.285 0.0446 2.4 2.3974 1.0 1987071 ChemDiv2_006065 CCN(CC)S(=O)(=O)c1ccc(Nc2nc3ccc(Cl)cc3n4cnnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D16 compound treatment 0.272 0.0316 1.7 1.6988 1.0 1987072 ChemDiv2_006066 COc1ccc(cc1)c2n[nH]c3c2cnc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D17 compound treatment 0.284 0.0436 2.34 2.3437 1.0 1987073 ChemDiv2_006067 O=C(CCc1nc2ccccc2[nH]1)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D18 compound treatment 0.45 0.21 11.26 11.2642 1.0 1987074 ChemDiv2_006068 CCC(=O)N1C(C)Cc2cc(ccc12)S(=O)(=O)CCC(=O)N3CCn4c3nc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D19 compound treatment 0.261 0.0206 1.11 1.1077 1.0 1987075 ChemDiv2_006069 CC1CCCCC1NC(=O)c2nnc(Cc3ccc(Cl)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D20 compound treatment 0.425 0.185 9.92 9.9207 1.0 1987076 ChemDiv2_006070 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)Nc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D21 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987077 ChemDiv2_006071 Fc1ccc(Cc2nnc(o2)C(=O)NC3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D22 compound treatment 0.568 0.328 17.61 17.6052 1.0 1987078 ChemDiv2_006072 CC1CCCCN1C(=O)c2cc3cc4ccc(C)cc4nc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D23 mock treatment 0.252 0.0116 0.62 0.6241 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 D24 mock treatment 0.232 -0.00839 -0.45 -0.4507 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E01 compound treatment 0.307 0.0666 3.58 3.5796 1.0 1987079 ChemDiv2_006073 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)NC(=C(C3c4ccccc4)C(=O)Nc5ccc(C)cc5)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E02 compound treatment 0.502 0.262 14.06 14.0585 1.0 1987080 ChemDiv2_006074 CC1CC(C)CN(C1)C(=O)Cn2c(=O)n(Cc3ccc(cc3)C(=O)NCc4ccco4)c(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E03 compound treatment 0.26 0.0196 1.05 1.054 1.0 1987081 ChemDiv2_006075 COc1cccc(c1)n2c(=O)n(CC(=O)NCC3CCCO3)c4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E04 compound treatment 0.345 0.105 5.62 5.6217 1.0 1987082 ChemDiv2_006076 O=C(CCCn1c(=O)n(CC(=O)c2ccccc2)c3ccccc3c1=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E05 compound treatment 0.487 0.247 13.25 13.2525 1.0 1987083 ChemDiv2_006077 O=C(CCCn1c(=O)n(CC(=O)c2ccccc2)c3ccsc3c1=O)NCc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E06 compound treatment 0.307 0.0666 3.58 3.5796 1.0 1987084 ChemDiv2_006078 O=C(Cn1c(=O)n(CC2CCCO2)c(=O)c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E07 compound treatment 0.319 0.0786 4.22 4.2245 1.0 1987085 ChemDiv2_006079 Fc1ccccc1Cn2c(=O)n(c3ccc(CC(=O)NCc4ccco4)cc3)c(=O)c5sccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E08 compound treatment 0.285 0.0446 2.4 2.3974 1.0 1987086 ChemDiv2_006080 CC1CCCCN1C(=O)Cn2c(=O)n(CCCS(=O)(=O)C3CCCCC3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E09 compound treatment 0.27 0.0296 1.59 1.5913 1.0 1987087 ChemDiv2_006081 CCOC(=O)CSc1nnc(CNC(=O)c2cccs2)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E10 compound treatment 0.512 0.272 14.6 14.5959 1.0 1987088 ChemDiv2_006082 Nc1nnc(CCCN2C(=O)c3ccccc3C2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E11 compound treatment 0.257 0.0166 0.89 0.8927 1.0 1987089 ChemDiv2_006083 CC1(CCC(=O)N1CCC2=CCCCC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E12 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987090 ChemDiv2_006084 COC(=O)C1C(C)Cc2[nH]c(C(=O)OC)c(C)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E13 compound treatment 0.332 0.0916 4.92 4.9231 1.0 1987091 ChemDiv2_006085 Clc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E14 compound treatment 0.244 0.00361 0.19 0.1941 1.0 1987092 ChemDiv2_006086 Cc1ccccc1C2CC(=O)NC3=C2C(=O)CCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E15 compound treatment 0.257 0.0166 0.89 0.8927 1.0 1987093 ChemDiv2_006087 O=C(NCCc1ccccc1)C2N(C3CCCCCC3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E16 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987094 ChemDiv2_006088 O=C1CC(C2=C(CC(CC2=O)c3cccs3)N1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E17 compound treatment 0.314 0.0736 3.96 3.9558 1.0 1987095 ChemDiv2_006089 CN(C(=O)Cn1c(=O)n(c2ccccc2)c(=O)c3c4CCCc4sc13)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E18 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987096 ChemDiv2_006090 COCCn1c(SCC(=O)N)nc2CC(C)Sc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E19 compound treatment 0.414 0.174 9.33 9.3296 1.0 1987097 ChemDiv2_006091 COc1ccccc1CNC(=O)C2CCN(CC2)S(=O)(=O)c3cccc4nonc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E20 compound treatment 0.251 0.0106 0.57 0.5703 1.0 1692093 ChemDiv2_006092 NC(=O)c1cccc(n1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E21 compound treatment 0.287 0.0466 2.5 2.5049 1.0 1987098 ChemDiv2_006093 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E22 compound treatment 0.284 0.0436 2.34 2.3437 1.0 1987099 ChemDiv2_006094 CC1CN(CCN1c2cccc(C)c2)C(=O)Cc3c([nH]c4ccc(Cl)cc34)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E23 mock treatment 0.258 0.0176 0.95 0.9465 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 E24 mock treatment 0.238 -0.00239 -0.13 -0.1283 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F01 compound treatment 0.482 0.242 12.98 12.9838 1.0 1987100 ChemDiv2_006095 CN(C(=O)CCc1nc(no1)c2ccc(C)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F02 compound treatment 0.594 0.354 19.0 19.0024 1.0 1987101 ChemDiv2_006096 CC1=Nc2cc(ccc2Sc3ccccc13)C(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F03 compound treatment 0.332 0.0916 4.92 4.9231 1.0 1987102 ChemDiv2_006097 Fc1ccccc1c2noc(CCC(=O)NC3CCCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F04 compound treatment 0.414 0.174 9.33 9.3296 1.0 1987103 ChemDiv2_006098 Cc1cc(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCC3)nc4c5ccccc5oc(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F05 compound treatment 0.422 0.182 9.76 9.7595 1.0 1987104 ChemDiv2_006099 Fc1ccccc1c2noc(CCC(=O)NCCN3CCc4ccccc4C3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F06 compound treatment 0.257 0.0166 0.89 0.8927 1.0 1987105 ChemDiv2_006100 Cn1cc(CC(=O)NCCN2CCOCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F07 compound treatment 0.242 0.00161 0.09 0.0867 1.0 1987106 ChemDiv2_006101 COc1ccc(C(N(Cc2ccccc2)C(C)C)c3c(O)[nH]c(=O)[nH]c3=O)c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F08 compound treatment 0.537 0.297 15.94 15.9394 1.0 1987107 ChemDiv2_006102 Cn1c(=NC(=O)CSCC(=O)N2CCCC2)sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F09 compound treatment 0.487 0.247 13.25 13.2525 1.0 1987108 ChemDiv2_006103 Brc1cc2CCN(C(=O)C3CC3)c2c(c1)S(=O)(=O)CCC(=O)N4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F10 compound treatment 0.309 0.0686 3.69 3.6871 1.0 1987109 ChemDiv2_006104 Cc1noc(C)c1S(=O)(=O)N(c2ccc(Br)cc2F)S(=O)(=O)c3c(C)noc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F11 compound treatment 0.275 0.0346 1.86 1.86 1.0 1987110 ChemDiv2_006105 COc1ccc(OC)c(Nc2cc(C)nc3nc(C)nn23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F12 compound treatment 0.365 0.125 6.7 6.6964 1.0 1987111 ChemDiv2_006106 COc1ccc(Nc2c(nc3ncccn23)c4ccc(O)c(OC)c4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F13 compound treatment 0.3 0.0596 3.2 3.2035 1.0 1987112 ChemDiv2_006107 COc1cccc(CNC(=O)c2cc(n[nH]2)C(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F14 compound treatment 0.323 0.0826 4.44 4.4394 1.0 1987113 ChemDiv2_006108 CCOC(=O)c1nnn(CC(=O)Nc2ccc(C)cc2Cl)c1C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F15 compound treatment 0.435 0.195 10.46 10.4581 1.0 1987114 ChemDiv2_006109 O=C(CCc1nc2ccccc2[nH]1)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F16 compound treatment 0.25 0.00961 0.52 0.5166 1.0 1987115 ChemDiv2_006110 CC(C)CCn1cccc1C2=NC(C)(C)CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F17 compound treatment 0.361 0.121 6.48 6.4815 1.0 1711491 ChemDiv2_006111 CCOC(=O)c1c[nH]c2ncnn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F18 compound treatment 0.462 0.222 11.91 11.909 1.0 1987116 ChemDiv2_006112 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)Nc3ccc(C)cn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F19 compound treatment 0.252 0.0116 0.62 0.6241 1.0 1987117 ChemDiv2_006113 Clc1ccc(Cc2nnc(o2)C(=O)N3CCOCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F20 compound treatment 0.339 0.0986 5.3 5.2993 1.0 1987118 ChemDiv2_006114 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F21 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987119 ChemDiv2_006115 Cc1nnc2c(nc3ccccc3n12)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F22 compound treatment 0.544 0.304 16.32 16.3155 1.0 1987120 ChemDiv2_006116 Cc1ccc2cc3cc(oc3nc2c1)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F23 mock treatment 0.25 0.00961 0.52 0.5166 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 F24 mock treatment 0.235 -0.00539 -0.29 -0.2895 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G01 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987121 ChemDiv2_006117 Cc1ccc(cc1)c2nc3[nH]cnn3c2Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G02 compound treatment 0.24 -3.87E-4 -0.02 -0.0208 -1.0 1987122 ChemDiv2_006118 Fc1cccc(Cn2c(=O)n(C3CCCC3)c(=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G03 compound treatment 0.262 0.0216 1.16 1.1614 1.0 1987123 ChemDiv2_006119 CCOc1ccc(cc1)n2c(=O)n(CC(=O)Nc3ccccc3C(=O)OC)c4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G04 compound treatment 0.397 0.157 8.42 8.416 1.0 1987124 ChemDiv2_006120 CCc1ccccc1NC(=O)Cn2c(=O)n(Cc3ccc4OCOc4c3)c(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G05 compound treatment 0.389 0.149 7.99 7.9861 1.0 1987125 ChemDiv2_006121 CC1CC(C)CN(C1)C(=O)Cn2c(=O)n(CCCC(=O)NCc3ccc4OCOc4c3)c(=O)c5sccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G06 compound treatment 0.487 0.247 13.25 13.2525 1.0 1987126 ChemDiv2_006122 Clc1ccc2c(=O)n(CCCC(=O)NCCN3CCN(CC3)c4ccccc4)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G07 compound treatment 0.493 0.253 13.57 13.5749 1.0 1987127 ChemDiv2_006123 Fc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(cc3)C(=O)NCc4ccco4)c(=O)c5sccc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G08 compound treatment 0.35 0.11 5.89 5.8904 1.0 1987128 ChemDiv2_006124 O=C(Cn1c(=O)n(CCCS(=O)(=O)C2CCCCC2)c(=O)c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G09 compound treatment 0.252 0.0116 0.62 0.6241 1.0 1987129 ChemDiv2_006125 COC(=O)CSc1nnc(CNC(=O)c2cccs2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G10 compound treatment 0.247 0.00661 0.36 0.3554 1.0 1987130 ChemDiv2_006126 CC(C)NC(=O)C1C(N(C)C(=O)c2ccccc12)c3cn(C)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G11 compound treatment 0.253 0.0126 0.68 0.6778 1.0 1987131 ChemDiv2_006127 COc1ccc(CCN2C(=O)CCC2(C)C(=O)NCc3cccnc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G12 compound treatment 0.259 0.0186 1.0 1.0002 1.0 1987132 ChemDiv2_006128 Clc1ccc(CCN2COc3cc4OCOc4cc3C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G13 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1276908 ChemDiv2_006129 Clc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G14 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987133 ChemDiv2_006130 CCOC(=O)c1[nH]c2CC(CC(=O)c2c1c3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G15 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987134 ChemDiv2_006131 O=C(NCCc1ccccc1)C2N(C3CC3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G16 compound treatment 0.253 0.0126 0.68 0.6778 1.0 1987135 ChemDiv2_006132 O=C1CC(C2=C(CCCC2=O)N1)c3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G17 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987136 ChemDiv2_006133 Cc1ccc(cc1C)n2c(=O)n(CC(=O)N)c3sc4CCCCCc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G18 compound treatment 0.296 0.0556 2.99 2.9885 1.0 1987137 ChemDiv2_006134 CC1Cc2nc(SCC(=O)N3CCCCC3)n(Cc4ccccc4)c(=O)c2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G19 compound treatment 0.33 0.0896 4.82 4.8156 1.0 1987138 ChemDiv2_006135 CCOc1ccc(OCC)c(NC(=O)C2CCCN(C2)S(=O)(=O)c3cccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G20 compound treatment 0.492 0.252 13.52 13.5212 1.0 1987139 ChemDiv2_006136 CC1Cc2cc(Br)cc(c2N1C(=O)C)S(=O)(=O)CCC(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G21 compound treatment 0.305 0.0646 3.47 3.4722 1.0 1987140 ChemDiv2_006137 CCOC(=O)Cn1c(=O)n(CCc2ccccc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G22 compound treatment 0.342 0.102 5.46 5.4605 1.0 1987141 ChemDiv2_006138 CC1CCCCN1C(=O)CCc2nc(no2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G23 mock treatment 0.248 0.00761 0.41 0.4091 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 G24 mock treatment 0.237 -0.00339 -0.18 -0.182 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H01 compound treatment 0.272 0.0316 1.7 1.6988 1.0 1987142 ChemDiv2_006139 CCOC(=O)N1CCC(CC1)NC(=O)CCc2nc(no2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H02 compound treatment 0.521 0.281 15.08 15.0796 1.0 1987143 ChemDiv2_006140 CC1=Nc2cc(ccc2Sc3ccccc13)C(=O)N4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H03 compound treatment 0.444 0.204 10.94 10.9417 1.0 1987144 ChemDiv2_006141 COc1ccc(NC(=O)CCc2nc(no2)c3ccccc3F)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H04 compound treatment 0.337 0.0966 5.19 5.1918 1.0 1987145 ChemDiv2_006142 COc1ccc(cc1)c2noc(CCC(=O)NC3CCCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H05 compound treatment 0.281 0.0406 2.18 2.1825 1.0 1987146 ChemDiv2_006143 Cc1ccc(NC(=O)c2c(C)nc3sc(C(=O)NC4CCCC4)c(N)c3c2c5cccnc5)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H06 compound treatment 0.244 0.00361 0.19 0.1941 1.0 1987147 ChemDiv2_006144 Cn1cc(CC(=O)NCc2ccccn2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H07 compound treatment 0.244 0.00361 0.19 0.1941 1.0 1987148 ChemDiv2_006145 CN(Cc1ccccc1)C(c2ccc(F)cc2)c3c(O)[nH]c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H08 compound treatment 0.354 0.114 6.11 6.1053 1.0 1987149 ChemDiv2_006146 O=C(Nc1nccs1)C2CCN(CC2)S(=O)(=O)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H09 compound treatment 0.536 0.296 15.89 15.8856 1.0 1987150 ChemDiv2_006147 Fc1ccc(CNC(=O)CCS(=O)(=O)c2cc(Br)cc3CCN(C(=O)C4CC4)c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H10 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987151 ChemDiv2_006148 CN(c1cccc(C)c1)S(=O)(=O)c2c(C)noc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H11 compound treatment 0.261 0.0206 1.11 1.1077 1.0 1987152 ChemDiv2_006149 CN(c1cccc(C)c1)c2cc(C)nc3nc(C)nn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H12 compound treatment 0.33 0.0896 4.82 4.8156 1.0 1987153 ChemDiv2_006150 COc1ccc(Nc2c(nc3ncccn23)c4ccc(C)o4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H13 compound treatment 0.367 0.127 6.8 6.8039 1.0 1987154 ChemDiv2_006151 Cc1cc(C)n(n1)c2nc3cc(C)ccc3nc2Nc4ccc5[nH]c(=O)[nH]c5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H14 compound treatment 0.246 0.00561 0.3 0.3016 1.0 1987155 ChemDiv2_006152 COc1cc(OC)c(NC(=O)Cn2nnc(C(=O)O)c2C(=O)O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H15 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987156 ChemDiv2_006153 Fc1ccc(CNC(=O)CCc2nc3ccccc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H16 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987157 ChemDiv2_006154 CCC1COC(=N1)c2cccn2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H17 compound treatment 0.365 0.125 6.7 6.6964 1.0 1987158 ChemDiv2_006155 O=C(c1ccccc1)c2ccc3nc(N4CCCCC4)c5nncn5c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H18 compound treatment 0.459 0.219 11.75 11.7478 1.0 1987159 ChemDiv2_006156 COc1ccc(NC(=O)CCS(=O)(=O)c2ccc3N(CCc3c2)C(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H19 compound treatment 0.273 0.0326 1.75 1.7525 1.0 1987160 ChemDiv2_006157 Clc1cnn(c2nc3ccccc3o2)c(=O)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H20 compound treatment 0.412 0.172 9.22 9.2221 1.0 1987161 ChemDiv2_006158 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)Nc3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H21 compound treatment 0.49 0.25 13.41 13.4137 1.0 1987162 ChemDiv2_006159 CC(C)NC(=O)c1cc2cc3ccc(C)cc3nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H22 compound treatment 0.542 0.302 16.21 16.208 1.0 1987163 ChemDiv2_006160 Cc1ccc2cc3cc(oc3nc2c1)C(=O)NCCCN4CCc5ccccc5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H23 mock treatment 0.241 6.13E-4 0.03 0.0329 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 H24 mock treatment 0.232 -0.00839 -0.45 -0.4507 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I01 compound treatment 0.243 0.00261 0.14 0.1404 1.0 1987164 ChemDiv2_006161 N(c1c(nc2[nH]cnn12)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I02 compound treatment 0.264 0.0236 1.27 1.2689 1.0 1987165 ChemDiv2_006162 CCOC(=O)Cn1c(=O)n(C2CCCC2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I03 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987166 ChemDiv2_006163 CC1CCCCN1C(=O)Cn2c(=O)n(c3ccc(F)cc3)c(=O)c4sccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I04 compound treatment 0.521 0.281 15.08 15.0796 1.0 1987167 ChemDiv2_006164 CN(Cc1ccccc1)C(=O)CCCn2c(=O)[nH]c3cc(Cl)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I05 compound treatment 0.349 0.109 5.84 5.8366 1.0 1987168 ChemDiv2_006165 CN(C(=O)Cn1c(=O)n(CCCC(=O)NCc2ccco2)c(=O)c3sccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I06 compound treatment 0.438 0.198 10.62 10.6193 1.0 1987169 ChemDiv2_006166 CC1CCCCN1C(=O)Cn2c(=O)n(CC3CCC(CC3)C(=O)NC4CCCC4)c(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I07 compound treatment 0.345 0.105 5.62 5.6217 1.0 1987170 ChemDiv2_006167 O=C(CCCn1c(=O)n(Cc2ccccc2)c3ccsc3c1=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I08 compound treatment 0.284 0.0436 2.34 2.3437 1.0 1987171 ChemDiv2_006168 C=CCn1c(=O)n(Cc2ccccc2)c3cc(ccc3c1=O)C(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I09 compound treatment 0.487 0.247 13.25 13.2525 1.0 1987172 ChemDiv2_006169 C(N1CCc2ccccc12)c3cn4c(nnc4s3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I10 compound treatment 0.416 0.176 9.44 9.4371 1.0 1987173 ChemDiv2_006170 CN1C(C(C(=O)Nc2ccccn2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I11 compound treatment 0.252 0.0116 0.62 0.6241 1.0 1987174 ChemDiv2_006171 CN(Cc1ccccc1)C(=O)C2(CC2)S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I12 compound treatment 0.264 0.0236 1.27 1.2689 1.0 1987175 ChemDiv2_006172 O=C1CC(c2ccccc2)c3cc4OCOc4cc3N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I13 compound treatment 0.341 0.101 5.41 5.4067 1.0 1987176 ChemDiv2_006173 CCOc1ccc(OCC)c(NC(=O)C2(CC2)S(=O)(=O)c3ccc(Cl)cc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I14 compound treatment 0.352 0.112 6.0 5.9978 1.0 1987177 ChemDiv2_006174 CCC(C)OC(=O)c1[nH]c2CC(CC(=O)c2c1C)c3ccc(cc3)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I15 compound treatment 0.427 0.187 10.03 10.0282 1.0 1987178 ChemDiv2_006175 CCOc1ccccc1CN2C(C(=O)NCCc3ccccc3)c4ccccc4C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I16 compound treatment 0.529 0.289 15.51 15.5095 1.0 1987179 ChemDiv2_006176 COc1ccc(OC)c2[nH]c(=O)c(CCNC(=O)c3ccco3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I17 compound treatment 0.264 0.0236 1.27 1.2689 1.0 1987180 ChemDiv2_006177 CCC(C)NC(=O)Cn1c(=O)n(c2ccccc2)c(=O)c3c4CCCCc4sc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I18 compound treatment 0.29 0.0496 2.67 2.6661 1.0 1987181 ChemDiv2_006178 CC1Cc2nc(SCC(=O)N)n(Cc3ccccc3)c(=O)c2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I19 compound treatment 0.241 6.13E-4 0.03 0.0329 1.0 1987182 ChemDiv2_006179 Cc1ccc(cc1)n2c(=O)n(CC(=O)NCCc3ccccc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I20 compound treatment 0.54 0.3 16.1 16.1006 1.0 1987183 ChemDiv2_006180 CC(=O)N1CCc2cc(Br)cc(c12)S(=O)(=O)CC(=O)Nc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I21 compound treatment 0.262 0.0216 1.16 1.1614 1.0 1987184 ChemDiv2_006181 CCN(Cc1ccccc1)C(=O)Cn2c(=O)n(CCc3ccccc3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I22 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987185 ChemDiv2_006182 CC1CCCC(NC(=O)CCc2nc(no2)c3ccc(C)cc3)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I23 mock treatment 0.247 0.00661 0.36 0.3554 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 I24 mock treatment 0.243 0.00261 0.14 0.1404 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J01 compound treatment 0.286 0.0456 2.45 2.4511 1.0 1987186 ChemDiv2_006183 Cc1ccc(cc1)c2noc(CCC(=O)NC3CC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J02 compound treatment 0.53 0.29 15.56 15.5632 1.0 1987187 ChemDiv2_006184 CC1=Nc2cc(ccc2Sc3ccccc13)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J03 compound treatment 0.476 0.236 12.66 12.6613 1.0 1987188 ChemDiv2_006185 Fc1ccccc1c2noc(CCC(=O)N3CCC4(CC3)OCCO4)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J04 compound treatment 0.57 0.33 17.71 17.7127 1.0 1987189 ChemDiv2_006186 COc1ccc(cc1)c2noc(CCC(=O)Nc3ccc4OCCOc4c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J05 compound treatment 0.517 0.277 14.86 14.8646 1.0 1987190 ChemDiv2_006187 CC1CCCCN1C(=O)CSc2nnc(COc3ccc(Cl)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J06 compound treatment 0.261 0.0206 1.11 1.1077 1.0 1987191 ChemDiv2_006188 CCN(CC)C(=O)Cc1cn(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J07 compound treatment 0.237 -0.00339 -0.18 -0.182 -1.0 1987192 ChemDiv2_006189 Oc1[nH]c(=O)[nH]c(=O)c1C(N2CCCC2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J08 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987193 ChemDiv2_006190 Cc1n[nH]c(C)c1S(=O)(=O)Nc2cc(C)cc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J09 compound treatment 0.305 0.0646 3.47 3.4722 1.0 1987194 ChemDiv2_006191 Cc1cc(Nc2ccc3OCCOc3c2)n4ncnc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J10 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987195 ChemDiv2_006192 CC1CCCN(CCCNS(=O)(=O)c2c(C)noc2C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J11 compound treatment 0.259 0.0186 1.0 1.0002 1.0 1987196 ChemDiv2_006193 Cc1nn(c(C)c1NC(=O)Cc2cccs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J12 compound treatment 0.435 0.195 10.46 10.4581 1.0 1987197 ChemDiv2_006194 O=C(CCc1nc(no1)c2cccs2)Nc3cnc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J13 compound treatment 0.433 0.193 10.35 10.3506 1.0 1987198 ChemDiv2_006195 OC(=O)Cc1ccc(Nc2nc3ccccc3n4nnnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J14 compound treatment 0.349 0.109 5.84 5.8366 1.0 1987199 ChemDiv2_006196 Cc1cc(C)cc(NS(=O)(=O)c2ccc3n(C)c(=O)n(C)c(=O)c3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J15 compound treatment 0.31 0.0696 3.74 3.7409 1.0 1987200 ChemDiv2_006197 CCOC(=O)N1CCC(CC1)Nc2nc3ccc(C)cc3nc2n4nc(C)cc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J16 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987201 ChemDiv2_006198 CC1(C)COC(=N1)c2cccn2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J17 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987202 ChemDiv2_006199 Oc1cc(CCl)nc2ncnn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J18 compound treatment 0.303 0.0626 3.36 3.3647 1.0 1987203 ChemDiv2_006200 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)Nc3cccc(F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J19 compound treatment 0.3 0.0596 3.2 3.2035 1.0 1987204 ChemDiv2_006201 CN(C)C(=O)c1nnc(Cc2ccc(Cl)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J20 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987205 ChemDiv2_006202 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)Nc3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J21 compound treatment 0.466 0.226 12.12 12.124 1.0 1987206 ChemDiv2_006203 CCCCN(C)C(=O)c1cc2cc3ccc(C)cc3nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J22 compound treatment 0.401 0.161 8.63 8.631 1.0 1987207 ChemDiv2_006204 Oc1nc(SCC=C)nc2n(ncc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J23 mock treatment 0.241 6.13E-4 0.03 0.0329 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 J24 mock treatment 0.242 0.00161 0.09 0.0867 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K01 compound treatment 0.265 0.0246 1.32 1.3226 1.0 1987208 ChemDiv2_006205 Oc1ccccc1c2nc3sccn3c2Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K02 compound treatment 0.254 0.0136 0.73 0.7315 1.0 1987209 ChemDiv2_006206 O=c1n(Cc2ccccc2C#N)c3ccccc3c(=O)n1C4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K03 compound treatment 0.246 0.00561 0.3 0.3016 1.0 1987210 ChemDiv2_006207 CCN(CC)C(=O)Cn1c(=O)n(c2ccccc2)c(=O)c3sccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K04 compound treatment 0.346 0.106 5.68 5.6754 1.0 1987211 ChemDiv2_006208 Clc1ccc2c(=O)n(CCCC(=O)NCC3CCCO3)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K05 compound treatment 0.343 0.103 5.51 5.5142 1.0 1987212 ChemDiv2_006209 CN(C1CCCCC1)C(=O)Cn2c(=O)n(CCCC(=O)NCc3ccco3)c(=O)c4sccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K06 compound treatment 0.466 0.226 12.12 12.124 1.0 1987213 ChemDiv2_006210 Cc1ccc(CNC(=O)CCCn2c(=O)n(CC(=O)c3ccccc3)c4ccccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K07 compound treatment 0.25 0.00961 0.52 0.5166 1.0 1987214 ChemDiv2_006211 CCOc1ccc(cc1)n2c(=O)n(CC(=O)N3CC(C)CC(C)C3)c4sc(C)c(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K08 compound treatment 0.277 0.0366 1.97 1.9675 1.0 1987215 ChemDiv2_006212 Fc1ccccc1NS(=O)(=O)c2ccc3[nH]c(nc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K09 compound treatment 0.333 0.0926 4.98 4.9768 1.0 1987216 ChemDiv2_006213 CCC(=O)Nc1cc2nc3[nH]c(=O)n(CCc4ccccc4)c(=O)c3nc2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K10 compound treatment 0.469 0.229 12.29 12.2852 1.0 1987217 ChemDiv2_006214 COc1cc(OC)c(NC(=O)C2C(N(C)C(=O)c3ccccc23)c4c[nH]c5ccccc45)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K11 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987218 ChemDiv2_006215 Cc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K12 compound treatment 0.312 0.0716 3.85 3.8483 1.0 1987219 ChemDiv2_006216 CCOC(=O)c1[nH]c2CC(CC(=O)c2c1c3ccc(OC)cc3)c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K13 compound treatment 0.254 0.0136 0.73 0.7315 1.0 1987220 ChemDiv2_006217 CCN(CC)C(=O)C1(CC1)S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K14 compound treatment 0.304 0.0636 3.42 3.4184 1.0 1987221 ChemDiv2_006218 Cc1ccc2C(CC(=O)Nc2c1C)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K15 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987222 ChemDiv2_006219 COc1ccc(CN2C(C(=O)NCC3CCCO3)c4ccccc4C2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K16 compound treatment 0.293 0.0526 2.83 2.8273 1.0 1987223 ChemDiv2_006220 CCC(CC)C(=O)NCCc1cc2ccc(C)cc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K17 compound treatment 0.309 0.0686 3.69 3.6871 1.0 1987224 ChemDiv2_006221 CN(CC(=O)NCc1ccccc1Cl)S(=O)(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K18 compound treatment 0.418 0.178 9.54 9.5445 1.0 1987225 ChemDiv2_006222 CCOc1ccc(cc1OCC)C(=O)NCCn2ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K19 compound treatment 0.265 0.0246 1.32 1.3226 1.0 1987226 ChemDiv2_006223 CCN(Cc1ccccc1)C(=O)Cn2c(=O)n(c3ccc(OC)cc3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K20 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987227 ChemDiv2_006224 Cc1cccc(C)c1NC(=O)CS(=O)(=O)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K21 compound treatment 0.248 0.00761 0.41 0.4091 1.0 1987228 ChemDiv2_006225 Cc1cc(NC(=O)Cn2c(=O)n(CCCC(=O)NCc3ccc4OCOc4c3)c(=O)c5ccccc25)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K22 compound treatment 0.304 0.0636 3.42 3.4184 1.0 1987229 ChemDiv2_006226 Cc1ccc(cc1)c2noc(CCC(=O)N3CCCc4ccccc34)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K23 mock treatment 0.238 -0.00239 -0.13 -0.1283 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 K24 mock treatment 0.246 0.00561 0.3 0.3016 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L01 compound treatment 0.253 0.0126 0.68 0.6778 1.0 1987230 ChemDiv2_006227 Cc1ccc(cc1)c2noc(CCC(=O)NC3CCCc4ccccc34)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L02 compound treatment 0.554 0.314 16.85 16.8529 1.0 1987231 ChemDiv2_006228 CCC1=Nc2cc(ccc2Sc3ccccc13)C(=O)NCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L03 compound treatment 0.54 0.3 16.1 16.1006 1.0 1987232 ChemDiv2_006229 CCN(C(=O)CCc1nc(no1)c2ccccc2F)c3cc(OC)ccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L04 compound treatment 0.461 0.221 11.86 11.8553 1.0 1987233 ChemDiv2_006230 COc1ccc(cc1)c2noc(CCC(=O)N3CCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L05 compound treatment 0.306 0.0656 3.53 3.5259 1.0 1987234 ChemDiv2_006231 CCOC(=O)N1CCN(CC1)C(=O)CSc2nnc(o2)C3COc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L06 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987235 ChemDiv2_006232 Cn1cc(CC(=O)NCCCN2CCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L07 compound treatment 0.243 0.00261 0.14 0.1404 1.0 1987236 ChemDiv2_006233 CC(C)N(Cc1ccccc1)C(c2ccc(F)cc2)c3c(O)[nH]c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L08 compound treatment 0.248 0.00761 0.41 0.4091 1.0 1987237 ChemDiv2_006234 Cc1n[nH]c(C)c1S(=O)(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L09 compound treatment 0.258 0.0176 0.95 0.9465 1.0 1987238 ChemDiv2_006235 Cc1cccc(N2CCN(CC2)c3nc4ccccc4n5nnnc35)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L10 compound treatment 0.261 0.0206 1.11 1.1077 1.0 1987239 ChemDiv2_006236 Cc1noc(C)c1S(=O)(=O)NCCN2CCC(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L11 compound treatment 0.28 0.0396 2.13 2.1287 1.0 1987240 ChemDiv2_006237 COC(=O)c1cc(Nc2cc(C)nc3ncnn23)cc(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L12 compound treatment 0.464 0.224 12.02 12.0165 1.0 1987241 ChemDiv2_006238 O=C(CCc1nc(no1)c2cccs2)Nc3cccc(C#N)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L13 compound treatment 0.318 0.0776 4.17 4.1708 1.0 1987242 ChemDiv2_006239 COc1cc(Nc2nc3ccccc3n4nnnc24)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L14 compound treatment 0.379 0.139 7.45 7.4488 1.0 1987243 ChemDiv2_006240 COc1cc(cc(OC)c1OC)n2cc(c3ccccc3)n(CC(=O)Nc4ccccc4C)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L15 compound treatment 0.247 0.00661 0.36 0.3554 1.0 1987244 ChemDiv2_006241 Cc1cc(C)n(n1)c2nc3cc(C)ccc3nc2NCc4ccc(cc4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L16 compound treatment 0.248 0.00761 0.41 0.4091 1.0 1987245 ChemDiv2_006242 Clc1ccc(Cn2cccc2C3=NCCO3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L17 compound treatment 0.261 0.0206 1.11 1.1077 1.0 1987246 ChemDiv2_006243 COc1cc(Cl)c(C)cc1NC(=O)CCc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L18 compound treatment 0.32 0.0796 4.28 4.2782 1.0 1987247 ChemDiv2_006244 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L19 compound treatment 0.321 0.0806 4.33 4.332 1.0 1987248 ChemDiv2_006245 Cc1ccc(Nc2cnn(c3nc4ccccc4o3)c(=O)c2Cl)cc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L20 compound treatment 0.373 0.133 7.13 7.1263 1.0 1987249 ChemDiv2_006246 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L21 compound treatment 0.536 0.296 15.89 15.8856 1.0 1987250 ChemDiv2_006247 Cc1ccc2cc3cc(sc3nc2c1)C(=O)NCC4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L22 compound treatment 0.268 0.0276 1.48 1.4839 1.0 1987251 ChemDiv2_006248 CC(C)Sc1nc(O)c2cnn(c3ccccc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L23 mock treatment 0.24 -3.87E-4 -0.02 -0.0208 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 L24 mock treatment 0.233 -0.00739 -0.4 -0.397 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M01 compound treatment 0.264 0.0236 1.27 1.2689 1.0 1987252 ChemDiv2_006249 Fc1ccccc1NC(=O)C2C3N(CCc4ccccc34)C(=O)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M02 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987253 ChemDiv2_006250 Cc1ccc(NC(=O)Cn2c(=O)n(CCc3ccccc3)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M03 compound treatment 0.247 0.00661 0.36 0.3554 1.0 1987254 ChemDiv2_006251 COc1cccc(NC(=O)Cn2c(=O)n(c3ccccc3)c(=O)c4sccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M04 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987255 ChemDiv2_006252 Clc1ccc(cc1)C(=O)Cn2c(=O)n(CCCC(=O)NCc3ccco3)c(=O)c4ccc(Cl)cc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M05 compound treatment 0.232 -0.00839 -0.45 -0.4507 -1.0 1987256 ChemDiv2_006253 CCN(CC)C(=O)Cn1c(=O)n(CC(=O)NCc2ccc(C)cc2)c(=O)c3sccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M06 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987257 ChemDiv2_006254 CC1CC(C)CN(C1)C(=O)Cn2c(=O)n(CCCC(=O)NCc3ccc(C)cc3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M07 compound treatment 0.238 -0.00239 -0.13 -0.1283 -1.0 1987258 ChemDiv2_006255 Cc1sc2n(CC(=O)NC3CCCC3)c(=O)n(Cc4ccccc4)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M08 compound treatment 0.478 0.238 12.77 12.7688 1.0 1166813 ChemDiv2_006256 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc4[nH]c(nc4c3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M09 compound treatment 0.329 0.0886 4.76 4.7619 1.0 1987259 ChemDiv2_006257 CCOc1ccc(NC(=O)CSc2ncnc3c4ccccc4oc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M10 compound treatment 0.257 0.0166 0.89 0.8927 1.0 1987260 ChemDiv2_006258 CN1C(C(C(=O)NCC2CCCO2)c3ccccc3C1=O)c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M11 compound treatment 0.246 0.00561 0.3 0.3016 1.0 1987261 ChemDiv2_006259 Cc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M12 compound treatment 0.425 0.185 9.92 9.9207 1.0 1987262 ChemDiv2_006260 COc1cc(cc(OC)c1OC)C2CC(=O)c3c(C)c([nH]c3C2)C(=O)OCCOc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M13 compound treatment 0.257 0.0166 0.89 0.8927 1.0 1987263 ChemDiv2_006261 Clc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)NCCCN3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M14 compound treatment 0.291 0.0506 2.72 2.7198 1.0 1987264 ChemDiv2_006262 O=C1CC(C2=C(CCCC2=O)N1)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M15 compound treatment 0.273 0.0326 1.75 1.7525 1.0 1987265 ChemDiv2_006263 CCOc1ccc(cc1)n2c(=O)n(Cc3cccnc3)c4sc5CCCc5c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M16 compound treatment 0.251 0.0106 0.57 0.5703 1.0 1987266 ChemDiv2_006264 CCOc1cc(cc(OCC)c1OCC)C(=O)NCCc2cc3c(C)ccc(C)c3[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M17 compound treatment 0.419 0.179 9.6 9.5983 1.0 1987267 ChemDiv2_006265 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M18 compound treatment 0.486 0.246 13.2 13.1987 1.0 1987268 ChemDiv2_006266 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCCn2ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M19 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987269 ChemDiv2_006267 COc1ccc(cc1OC)n2c(=O)n(Cc3ccccc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M20 compound treatment 0.39 0.15 8.04 8.0399 1.0 1987270 ChemDiv2_006268 CCOc1ccc(NC(=O)CS(=O)(=O)c2cccc3nsnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M21 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987271 ChemDiv2_006269 Cc1cccc(Cn2c(=O)n(Cc3ccco3)c(=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M22 compound treatment 0.27 0.0296 1.59 1.5913 1.0 1987272 ChemDiv2_006270 CCN1CCCC1CNC(=O)CCc2nc(no2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M23 mock treatment 0.248 0.00761 0.41 0.4091 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 M24 mock treatment 0.241 6.13E-4 0.03 0.0329 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N01 compound treatment 0.272 0.0316 1.7 1.6988 1.0 1987273 ChemDiv2_006271 CCc1cccc(NC(=O)CCc2nc(no2)c3ccc(C)cc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N02 compound treatment 0.521 0.281 15.08 15.0796 1.0 1987274 ChemDiv2_006272 CCCC1=Nc2cc(ccc2Sc3ccccc13)C(=O)NCCCN4CCN(C)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N03 compound treatment 0.279 0.0386 2.07 2.075 1.0 1987275 ChemDiv2_006273 Fc1ccccc1c2noc(CCC(=O)N3CCN(CC3)C4CCCCC4)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N04 compound treatment 0.26 0.0196 1.05 1.054 1.0 1987276 ChemDiv2_006274 CCOC(=O)c1ccccc1NC(=O)CCc2nc(no2)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N05 compound treatment 0.246 0.00561 0.3 0.3016 1.0 1987277 ChemDiv2_006275 COCCN1C(C(C(=O)NC(C)C)c2ccccc2C1=O)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N06 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987278 ChemDiv2_006276 Cn1cc(CC(=O)N2CCN(CC2)C3CCCCC3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N07 compound treatment 0.248 0.00761 0.41 0.4091 1.0 1987279 ChemDiv2_006277 CC(C)N(Cc1ccccc1)C(c2cccs2)c3c(O)[nH]c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N08 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987280 ChemDiv2_006278 Cc1n[nH]c(C)c1S(=O)(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N09 compound treatment 0.31 0.0696 3.74 3.7409 1.0 1987281 ChemDiv2_006279 C1Oc2ccc(Nc3nc4ccccc4n5nnnc35)cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N10 compound treatment 0.359 0.119 6.37 6.374 1.0 1987282 ChemDiv2_006280 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)NCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N11 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987283 ChemDiv2_006281 Cc1cc(N2CCc3ccccc23)n4ncnc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N12 compound treatment 0.301 0.0606 3.26 3.2572 1.0 1987284 ChemDiv2_006282 COc1ccc(cc1OC)c2nc(SCC(=O)NCC3CCCO3)c([nH]2)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N13 compound treatment 0.266 0.0256 1.38 1.3764 1.0 1987285 ChemDiv2_006283 Cc1cc(C)n(n1)c2nc3ccccc3nc2Nc4ccc(CC(=O)O)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N14 compound treatment 0.365 0.125 6.7 6.6964 1.0 1987286 ChemDiv2_006284 Cc1cccc(C)c1NC(=O)Cn2c(cn(c3ccccc3)c2=O)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N15 compound treatment 0.372 0.132 7.07 7.0726 1.0 1987287 ChemDiv2_006285 O=C(CCc1nc2ccccc2[nH]1)N3CCC(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N16 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987288 ChemDiv2_006286 COc1ccc(Cn2cccc2C3=NCCO3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N17 compound treatment 0.34 0.0996 5.35 5.353 1.0 1987289 ChemDiv2_006287 O=C(CCc1nc2ccccc2[nH]1)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N18 compound treatment 0.331 0.0906 4.87 4.8693 1.0 1987290 ChemDiv2_006288 CC(=O)N1CCc2cc(ccc12)S(=O)(=O)CCC(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N19 compound treatment 0.528 0.288 15.46 15.4557 1.0 1987291 ChemDiv2_006289 Clc1c(cnn(c2nc3ccccc3o2)c1=O)N4CCN(CC4)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N20 compound treatment 0.561 0.321 17.23 17.2291 1.0 1987292 ChemDiv2_006290 Cc1ccc2cc3cc(oc3nc2c1)C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N21 compound treatment 0.369 0.129 6.91 6.9114 1.0 1987293 ChemDiv2_006291 COc1ccc2cc3cc(sc3nc2c1)C(=O)NCc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N22 compound treatment 0.235 -0.00539 -0.29 -0.2895 -1.0 1987294 ChemDiv2_006292 Oc1nc(SCc2ccccc2)nc3n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N23 mock treatment 0.238 -0.00239 -0.13 -0.1283 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 N24 mock treatment 0.225 -0.0154 -0.83 -0.8269 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O01 compound treatment 0.235 -0.00539 -0.29 -0.2895 -1.0 1987295 ChemDiv2_006293 CC(C)NC(=O)C1C2N(CCc3ccccc23)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O02 compound treatment 0.264 0.0236 1.27 1.2689 1.0 1987296 ChemDiv2_006294 Clc1ccc(NC(=O)Cn2c(=O)n(CCc3ccccc3)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O03 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987297 ChemDiv2_006295 O=C(Cn1c(=O)n(c2ccccc2)c(=O)c3sccc13)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O04 compound treatment 0.312 0.0716 3.85 3.8483 1.0 1987298 ChemDiv2_006296 Fc1ccc(F)c(NC(=O)Cn2c(=O)n(c3ccc(CC(=O)NCC4CCCO4)cc3)c(=O)c5ccccc25)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O05 compound treatment 0.253 0.0126 0.68 0.6778 1.0 1987299 ChemDiv2_006297 COc1ccc(CCNC(=O)Cn2c(=O)n(CC(=O)N3CCCCC3C)c4ccsc4c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O06 compound treatment 0.265 0.0246 1.32 1.3226 1.0 1987300 ChemDiv2_006298 Fc1cccc(NC(=O)Cn2c(=O)n(CC(=O)NC3CCCC3)c(=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O07 compound treatment 0.266 0.0256 1.38 1.3764 1.0 1987301 ChemDiv2_006299 COc1ccc(CCNC(=O)Cn2c(=O)n(CCc3ccccc3)c(=O)c4c(C)c(C)sc24)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O08 compound treatment 0.44 0.2 10.73 10.7268 1.0 1987302 ChemDiv2_006300 CCOC(=O)c1ccc(NC(=O)CSc2nccn2c3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O09 compound treatment 0.254 0.0136 0.73 0.7315 1.0 1987303 ChemDiv2_006301 O=C(CSc1ncnc2c3ccccc3oc12)NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O10 compound treatment 0.248 0.00761 0.41 0.4091 1.0 1987304 ChemDiv2_006302 CC(C)NC(=O)C1C(N(C)C(=O)c2ccccc12)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O11 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987305 ChemDiv2_006303 CC(NC(=O)C1(CC1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O12 compound treatment 0.239 -0.00139 -0.07 -0.0745 -1.0 1987306 ChemDiv2_006304 Brc1ccccc1C2CC(=O)NC3=C2C(=O)CCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O13 compound treatment 0.241 6.13E-4 0.03 0.0329 1.0 1987307 ChemDiv2_006305 CC1CCC(CC1)NC(=O)C2N(CCCN3CCOCC3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O14 compound treatment 0.252 0.0116 0.62 0.6241 1.0 1987308 ChemDiv2_006306 Cn1c2NC(=O)CC(c3cc4OCOc4cc3Br)c2c(=O)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O15 compound treatment 0.249 0.00861 0.46 0.4628 1.0 1987309 ChemDiv2_006307 COc1cccc(c1)n2c(=O)n(CC(=O)NC3CCCC3)c4sc5CCCCc5c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O16 compound treatment 0.273 0.0326 1.75 1.7525 1.0 1987310 ChemDiv2_006308 CC1Cc2nc(SCC(=O)N)n(C)c(=O)c2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O17 compound treatment 0.381 0.141 7.56 7.5562 1.0 1987311 ChemDiv2_006309 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O18 compound treatment 0.242 0.00161 0.09 0.0867 1.0 1987312 ChemDiv2_006310 Cc1nc2c3c(nc(nc3nn2c(C)c1CCC(=O)O)N4CCCCC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O19 compound treatment 0.236 -0.00439 -0.24 -0.2358 -1.0 1987313 ChemDiv2_006311 COc1ccc(cc1OC)n2c(=O)n(CC(=O)OCc3ccccc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O20 compound treatment 0.244 0.00361 0.19 0.1941 1.0 1987314 ChemDiv2_006312 CCN(C(=O)CS(=O)(=O)c1cccc2nsnc12)c3ccc(C)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O21 compound treatment 0.259 0.0186 1.0 1.0002 1.0 1987315 ChemDiv2_006313 Clc1cccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O22 compound treatment 0.291 0.0506 2.72 2.7198 1.0 1987316 ChemDiv2_006314 Cc1ccc(cc1)c2noc(CCC(=O)Nc3ccc4OCOc4c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O23 mock treatment 0.245 0.00461 0.25 0.2479 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 O24 mock treatment 0.236 -0.00439 -0.24 -0.2358 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P01 compound treatment 0.279 0.0386 2.07 2.075 1.0 1987317 ChemDiv2_006315 Cc1ccc(cc1)c2noc(CCC(=O)NCC3CCN(Cc4cccc(C)c4)CC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P02 compound treatment 0.532 0.292 15.67 15.6707 1.0 1987318 ChemDiv2_006316 CCCC1=Nc2cc(ccc2Sc3ccccc13)C(=O)NCCN4CCN(CC)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P03 compound treatment 0.442 0.202 10.83 10.8343 1.0 1987319 ChemDiv2_006317 CCCN(C(=O)CCc1nc(no1)c2ccccc2F)c3ccc(OCC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P04 compound treatment 0.461 0.221 11.86 11.8553 1.0 1987320 ChemDiv2_006318 CCOc1ccc(cc1)N(CC)C(=O)CCc2nc(no2)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P05 compound treatment 0.263 0.0226 1.22 1.2152 1.0 1987321 ChemDiv2_006319 COCCN1C(C(C(=O)NCc2cc(OC)ccc2OC)c3ccccc3C1=O)c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P06 compound treatment 0.259 0.0186 1.0 1.0002 1.0 1987322 ChemDiv2_006320 Cn1cc(CC(=O)NCCN2CCN(Cc3ccccc3)CC2)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P07 compound treatment 0.248 0.00761 0.41 0.4091 1.0 1987323 ChemDiv2_006321 Cc1ccc(cc1)C(N2CCCC2)c3c(O)[nH]c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P08 compound treatment 0.239 -0.00139 -0.07 -0.0745 -1.0 1987324 ChemDiv2_006322 Cc1noc(C)c1S(=O)(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P09 compound treatment 0.242 0.00161 0.09 0.0867 1.0 1987325 ChemDiv2_006323 COc1cc(Nc2cc(C)nc3ncnn23)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P10 compound treatment 0.297 0.0566 3.04 3.0423 1.0 1987326 ChemDiv2_006324 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)N(C)CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P11 compound treatment 0.256 0.0156 0.84 0.839 1.0 1987327 ChemDiv2_006325 CCN(c1ccccc1)c2cc(C)nc3ncnn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P12 compound treatment 0.275 0.0346 1.86 1.86 1.0 1987328 ChemDiv2_006326 COc1cc(cc(OC)c1OC)c2nc(SCC(=O)NC3CCCC3)c([nH]2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P13 compound treatment 0.371 0.131 7.02 7.0189 1.0 1987329 ChemDiv2_006327 CC(C)c1cc([nH]n1)C(=O)Nc2ccc(Br)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P14 compound treatment 0.242 0.00161 0.09 0.0867 1.0 1987330 ChemDiv2_006328 CCOC(=O)Cn1nc(c2ccccc2)c3cnc4ccccc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P15 compound treatment 0.245 0.00461 0.25 0.2479 1.0 1987331 ChemDiv2_006329 CCOC(=O)N1CCN(CC1)C(=O)CCc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P16 compound treatment 0.224 -0.0164 -0.88 -0.8806 -1.0 1987332 ChemDiv2_006330 CCc1ccccc1NC(=O)Cn2cccc2C3=NC(CO3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P17 compound treatment 0.231 -0.00939 -0.5 -0.5044 -1.0 1987333 ChemDiv2_006331 CCOc1ccc(CCNC(=O)c2nnc(Cc3ccc(Cl)cc3)o2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P18 compound treatment 0.266 0.0256 1.38 1.3764 1.0 1987334 ChemDiv2_006332 CN(C(=O)CCS(=O)(=O)c1ccc2N(CCc2c1)C(=O)C)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P19 compound treatment 0.255 0.0146 0.79 0.7853 1.0 1987335 ChemDiv2_006333 Clc1c(NCCc2ccccc2)cnn(c3nc4ccccc4o3)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P20 compound treatment 0.434 0.194 10.4 10.4044 1.0 1987336 ChemDiv2_006334 CN(C1CCCCC1)C(=O)c2cc3cc4ccc(C)cc4nc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P21 compound treatment 0.271 0.0306 1.65 1.6451 1.0 1987337 ChemDiv2_006335 CCC1CCCCN1C(=O)c2cc3cc4cc(OC)ccc4nc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P22 compound treatment 0.229 -0.0114 -0.61 -0.6119 -1.0 1987338 ChemDiv2_006336 Oc1nc(SCC(=O)Nc2ccccc2)nc3n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P23 mock treatment 0.211 -0.0294 -1.58 -1.5792 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1386 P24 mock treatment 0.232 -0.00839 -0.45 -0.4507 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A01 mock treatment 0.207 -0.0303 -1.63 -1.6277 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A02 mock treatment 0.217 -0.0203 -1.09 -1.0904 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A03 compound treatment 0.209 -0.0283 -1.52 -1.5203 -1.0 1987339 ChemDiv2_006337 CC(NC(=O)C1=C(C)C(=O)OC21CCC(C)CC2)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A04 compound treatment 0.225 -0.0123 -0.66 -0.6605 -1.0 1987340 ChemDiv2_006338 CC(C)c1ccc(cc1)N(CC(=O)N2CCCCCC2)S(=O)(=O)c3c(C)noc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A05 compound treatment 0.531 0.294 15.78 15.7833 1.0 1987341 ChemDiv2_006339 CN(Cc1ccccc1)C(=O)c2ccc3c(c2)N(Cc4ccccc4)C(=O)c5ccccc5S3(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A06 compound treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1987342 ChemDiv2_006340 CC1CCCCN1S(=O)(=O)c2coc(c2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A07 compound treatment 0.276 0.0387 2.08 2.0802 1.0 1987343 ChemDiv2_006341 CCCCN(C)C(=O)c1ccc2S(=O)c3ccccc3C(=O)N(Cc4ccccc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A08 compound treatment 0.228 -0.00929 -0.5 -0.4992 -1.0 1987344 ChemDiv2_006342 CN(Cc1ccccc1)S(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A09 compound treatment 0.363 0.126 6.76 6.7554 1.0 1987345 ChemDiv2_006343 CC1CCCC(NC(=O)CS(=O)(=O)Cc2nc(oc2C)c3ccccc3F)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A10 compound treatment 0.214 -0.0233 -1.25 -1.2516 -1.0 1987346 ChemDiv2_006344 COc1ccc(cc1)n2c(Cc3cc(=O)[nH]c(=O)[nH]3)nnc2SCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A11 compound treatment 0.279 0.0417 2.24 2.2414 1.0 1987347 ChemDiv2_006345 Cc1oc(nc1CS(=O)CC(=O)NC2CC2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A12 compound treatment 0.265 0.0277 1.49 1.4891 1.0 1987348 ChemDiv2_006346 Clc1ccc2nc3CCCCc3c(SCC(=O)NC4CC4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A13 compound treatment 0.261 0.0237 1.27 1.2741 1.0 1987349 ChemDiv2_006347 Cc1oc(nc1CSCC(=O)NCCN2CCCC2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A14 compound treatment 0.263 0.0257 1.38 1.3816 1.0 1987350 ChemDiv2_006348 CN1CCN(CC1)C(=O)c2cc3c(nn(C)c3s2)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A15 compound treatment 0.278 0.0407 2.19 2.1877 1.0 1987351 ChemDiv2_006349 COc1ccc(cc1OC)c2nc(CSCC(=O)NC(C)C)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A16 compound treatment 0.275 0.0377 2.03 2.0264 1.0 1987352 ChemDiv2_006350 CCOC(=O)c1cccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A17 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987353 ChemDiv2_006351 Cc1oc(nc1CN2CCC(CC2)C(=O)NCc3ccccc3)c4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A18 compound treatment 0.26 0.0227 1.22 1.2204 1.0 1987354 ChemDiv2_006352 Cn1c(cc2c(=O)[nH]c3ccccc3c12)C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A19 compound treatment 0.469 0.232 12.45 12.4516 1.0 1987355 ChemDiv2_006353 CCc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A20 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987356 ChemDiv2_006354 NC(=O)Cn1c(=O)n(c2ccccc2)c(=O)c3ccc(cc13)C(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A21 compound treatment 0.272 0.0347 1.87 1.8652 1.0 1987357 ChemDiv2_006355 Brc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A22 compound treatment 0.239 0.00171 0.09 0.0919 1.0 1987358 ChemDiv2_006356 CC1CCCCN1C(=O)CN(C)S(=O)(=O)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A23 compound treatment 0.507 0.27 14.49 14.4936 1.0 1987359 ChemDiv2_006357 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NCCCN3CCN(CC3)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 A24 compound treatment 0.288 0.0507 2.73 2.725 1.0 1987360 ChemDiv2_006358 Cn1c(=O)n(C)c2nc(CN3CCN(Cc4ccccc4)CC3)n(CCCc5ccccc5)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B01 mock treatment 0.239 0.00171 0.09 0.0919 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B02 mock treatment 0.25 0.0127 0.68 0.683 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B03 compound treatment 0.245 0.00771 0.41 0.4143 1.0 1987361 ChemDiv2_006359 CC1CN(Cc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc4c(F)cccc4Cl)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B04 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987362 ChemDiv2_006360 O=C(Cn1ncc2c(=O)oc3ccccc3c12)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B05 compound treatment 0.43 0.193 10.36 10.3558 1.0 1987363 ChemDiv2_006361 COc1ccc(CCNC(=O)c2cnc3scc(C)n3c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B06 compound treatment 0.227 -0.0103 -0.55 -0.553 -1.0 1987364 ChemDiv2_006362 COCCN1Cc2cccc(C(=O)Nc3ccccc3C)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B07 compound treatment 0.254 0.0167 0.9 0.8979 1.0 1987365 ChemDiv2_006363 CCOc1ccc(CCNS(=O)(=O)c2c[nH]cn2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B08 compound treatment 0.266 0.0287 1.54 1.5428 1.0 1987366 ChemDiv2_006364 CC(C)(C)OC(=O)N1CCC(CC1)c2cc(O)n3ncc(C(=O)NC4CCCC4)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B09 compound treatment 0.339 0.102 5.47 5.4657 1.0 1987367 ChemDiv2_006365 CCOc1ccc(NS(=O)(=O)c2c[nH]cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B10 compound treatment 0.234 -0.00329 -0.18 -0.1768 -1.0 1987368 ChemDiv2_006366 CCOC(=O)CN1CC2(OC3C=C2)C(C3C(=O)NCc4cccs4)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B11 compound treatment 0.313 0.0757 4.07 4.0685 1.0 1987369 ChemDiv2_006367 COc1cccc(c1)c2nn(C)c3sc(cc23)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B12 compound treatment 0.261 0.0237 1.27 1.2741 1.0 1987370 ChemDiv2_006368 Cc1n[nH]c2C(=O)N(C(c12)c3cccnc3)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B13 compound treatment 0.451 0.214 11.48 11.4843 1.0 1987371 ChemDiv2_006369 Cc1ccc(CNC(=O)c2cc3c(=O)[nH]c4ccccc4c3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B14 compound treatment 0.468 0.231 12.4 12.3979 1.0 1987372 ChemDiv2_006370 CCOc1ccc(CCNC(=O)c2ccc(cc2)N3CCCC3=O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B15 compound treatment 0.277 0.0397 2.13 2.1339 1.0 1987373 ChemDiv2_006371 CCOC(=O)N1CCC(CC1)N2Cc3cccc(C(=O)NCc4ccc5OCOc5c4)c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B16 compound treatment 0.415 0.178 9.55 9.5497 1.0 1987374 ChemDiv2_006372 CCOc1ccc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCCCC4)c(=O)c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B17 compound treatment 0.289 0.0517 2.78 2.7788 1.0 1987375 ChemDiv2_006373 COCCN1Cc2cccc(C(=O)NCc3ccco3)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B18 compound treatment 0.347 0.11 5.9 5.8956 1.0 1987376 ChemDiv2_006374 CCN1CCN(CC1)C(=O)c2ccc(CNS(=O)(=O)c3ccc(Br)cc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B19 compound treatment 0.26 0.0227 1.22 1.2204 1.0 1987377 ChemDiv2_006375 CCOC(=O)CSc1nc2cc(OC)c(OC)cc2c3nc(CCn4c(C)nc5ccccc45)nn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B20 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1656107 ChemDiv2_006376 COC(=O)c1cc(NC(=O)c2oc(=O)c3ccccc3c2c4ccc(C)cc4)cc(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B21 compound treatment 0.257 0.0197 1.06 1.0592 1.0 1987378 ChemDiv2_006377 Cc1nc2sc(C(N3CCN(CC3)C(=O)c4ccco4)c5ccco5)c(O)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B22 compound treatment 0.261 0.0237 1.27 1.2741 1.0 1987379 ChemDiv2_006378 COc1cccc(c1)n2c(C)nc3n(ncc3c2=O)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B23 compound treatment 0.243 0.00571 0.31 0.3068 1.0 1987380 ChemDiv2_006379 COc1ccc(Br)cc1CNC(=O)Cn2ncc3c(=O)oc4ccccc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 B24 compound treatment 0.531 0.294 15.78 15.7833 1.0 1987381 ChemDiv2_006380 COc1ccc2nc3oc(cc3cc2c1)C(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C01 mock treatment 0.217 -0.0203 -1.09 -1.0904 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C02 mock treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C03 compound treatment 0.243 0.00571 0.31 0.3068 1.0 1987382 ChemDiv2_006381 CC(C)CCNC(=O)C1=C(C)C(=O)OC21CCC(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C04 compound treatment 0.238 7.1E-4 0.04 0.0381 1.0 1987383 ChemDiv2_006382 CN(C(=O)CN(c1ccc2OCOc2c1)S(=O)(=O)c3c(C)noc3C)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C05 compound treatment 0.536 0.299 16.05 16.052 1.0 1987384 ChemDiv2_006383 Fc1ccccc1CN2C(=O)c3ccccc3S(=O)(=O)c4ccc(cc24)C(=O)NCCCN5CCCC5=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C06 compound treatment 0.245 0.00771 0.41 0.4143 1.0 1987385 ChemDiv2_006384 NC(=O)c1cc(co1)S(=O)(=O)Nc2cccc(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C07 compound treatment 0.273 0.0357 1.92 1.919 1.0 1987386 ChemDiv2_006385 CCN(CC)C(=O)c1ccc2S(=O)c3ccccc3C(=O)N(Cc4ccc(F)cc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C08 compound treatment 0.353 0.116 6.22 6.218 1.0 1987387 ChemDiv2_006386 CCOC(=O)c1cn(CC(=O)Nc2cccc(OC)c2)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C09 compound treatment 0.312 0.0747 4.01 4.0147 1.0 1987388 ChemDiv2_006387 Cc1oc(nc1CS(=O)(=O)CC(=O)N2CCCC2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C10 compound treatment 0.252 0.0147 0.79 0.7905 1.0 1987389 ChemDiv2_006388 CCOC(=O)C(C)Sc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C11 compound treatment 0.332 0.0947 5.09 5.0895 1.0 1987390 ChemDiv2_006389 Cc1oc(nc1CS(=O)CC(=O)NCCc2ccccc2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C12 compound treatment 0.279 0.0417 2.24 2.2414 1.0 1987391 ChemDiv2_006390 CN1CCN(CCCNC(=O)CSc2c3CCCCc3nc4ccc(Cl)cc24)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C13 compound treatment 0.458 0.221 11.86 11.8605 1.0 1987392 ChemDiv2_006391 Cc1oc(nc1CSCC(=O)NCCc2ccccc2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C14 compound treatment 0.464 0.227 12.18 12.1829 1.0 1987393 ChemDiv2_006392 COc1ccc2nc(sc2c1)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C15 compound treatment 0.543 0.306 16.43 16.4282 1.0 1987394 ChemDiv2_006393 COc1ccc(cc1)c2nc(CSCC(=O)N3CCCC3)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C16 compound treatment 0.453 0.216 11.59 11.5918 1.0 1987395 ChemDiv2_006394 COc1ccc(CNC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C17 compound treatment 0.276 0.0387 2.08 2.0802 1.0 1987396 ChemDiv2_006395 Cc1oc(nc1CN2CCC(CC2)C(=O)NCc3ccc4OCOc4c3)c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C18 compound treatment 0.273 0.0357 1.92 1.919 1.0 1987397 ChemDiv2_006396 CC(C1Sc2ccccc2N(Cc3ccccc3F)C1=O)C(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C19 compound treatment 0.254 0.0167 0.9 0.8979 1.0 1987398 ChemDiv2_006397 Cc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)NCCN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C20 compound treatment 0.332 0.0947 5.09 5.0895 1.0 1987399 ChemDiv2_006398 COc1ccc(cc1)N(C)C(=O)C(NS(=O)(=O)c2cccc3nsnc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C21 compound treatment 0.273 0.0357 1.92 1.919 1.0 1987400 ChemDiv2_006399 Brc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C22 compound treatment 0.396 0.159 8.53 8.5287 1.0 1987401 ChemDiv2_006400 COc1ccc(CNC(=O)C(NS(=O)(=O)c2cccc3nsnc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C23 compound treatment 0.38 0.143 7.67 7.6689 1.0 1987402 ChemDiv2_006401 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NCCN3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 C24 compound treatment 0.254 0.0167 0.9 0.8979 1.0 1987403 ChemDiv2_006402 CC1CC(C)CN(Cc2nc3n(C)c(=O)n(C)c(=O)c3n2CCCO)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D01 mock treatment 0.248 0.0107 0.58 0.5755 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D02 mock treatment 0.248 0.0107 0.58 0.5755 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D03 compound treatment 0.239 0.00171 0.09 0.0919 1.0 1987404 ChemDiv2_006403 CCn1c(CN2CCN(CC2)c3ccccc3F)nc4n(C)c(=O)n(C)c(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D04 compound treatment 0.31 0.0727 3.91 3.9073 1.0 1987405 ChemDiv2_006404 O=C(Cn1ncc2c(=O)oc3ccccc3c12)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D05 compound treatment 0.331 0.0937 5.04 5.0358 1.0 1987406 ChemDiv2_006405 Cc1csc2ncc(C(=O)NCc3cccs3)c(=O)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D06 compound treatment 0.311 0.0737 3.96 3.961 1.0 1987407 ChemDiv2_006406 Cc1nn(c2ccccc2)c3[nH]c(=O)cc(CCl)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D07 compound treatment 0.246 0.00871 0.47 0.468 1.0 1987408 ChemDiv2_006407 Cc1cccc(NS(=O)(=O)c2c[nH]cn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D08 compound treatment 0.318 0.0807 4.34 4.3372 1.0 1987409 ChemDiv2_006408 CC(C)(C)OC(=O)N1CCC(CC1)c2cc(O)n3ncc(C(=O)NCc4ccco4)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D09 compound treatment 0.243 0.00571 0.31 0.3068 1.0 1987410 ChemDiv2_006409 CC1CCCCN1S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D10 compound treatment 0.244 0.00671 0.36 0.3606 1.0 1987411 ChemDiv2_006410 CCOC(=O)N1CCC(CC1)N2CC3(OC4C=C3)C(C4C(=O)Nc5ccc(C)c(F)c5)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D11 compound treatment 0.5 0.263 14.12 14.1175 1.0 1987412 ChemDiv2_006411 COc1cccc(c1)c2nn(C)c3sc(cc23)C(=O)NCCc4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D12 compound treatment 0.287 0.0497 2.67 2.6713 1.0 1987413 ChemDiv2_006412 OC(=O)c1ccc(cc1)N2C(c3c(n[nH]c3C2=O)c4ccccc4)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D13 compound treatment 0.424 0.187 10.03 10.0334 1.0 1987414 ChemDiv2_006413 O=C(NC1CC1)c2cc3c(=O)[nH]c4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D14 compound treatment 0.303 0.0657 3.53 3.5311 1.0 1987415 ChemDiv2_006414 CCN1CCCC1CNC(=O)c2ccc(cc2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D15 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987416 ChemDiv2_006415 CCOC(=O)N1CCC(CC1)N2Cc3cccc(C(=O)Nc4ccc(OC)c(OC)c4)c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D16 compound treatment 0.295 0.0577 3.1 3.1012 1.0 1987417 ChemDiv2_006416 Fc1ccccc1NS(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCCC4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D17 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987418 ChemDiv2_006417 COCCN1Cc2cccc(C(=O)NC3CCCCCC3)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D18 compound treatment 0.279 0.0417 2.24 2.2414 1.0 1987419 ChemDiv2_006418 CCN1CCN(CC1)C(=O)c2ccc(CNS(=O)(=O)c3ccc(C)cc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D19 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987420 ChemDiv2_006419 COc1cc2nc(SCC#N)n3nc(CCn4c(C)nc5ccccc45)nc3c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D20 compound treatment 0.261 0.0237 1.27 1.2741 1.0 1987421 ChemDiv2_006420 O=C(NCCCN1CCCCC1)c2oc(=O)c3ccccc3c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D21 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987422 ChemDiv2_006421 Cc1nc2sc(C(N3CCc4ccccc4C3)c5ccccc5)c(O)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D22 compound treatment 0.55 0.313 16.8 16.8044 1.0 1987423 ChemDiv2_006422 Clc1ccc2cc3cc(oc3nc2c1)C(=O)NCCCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D23 compound treatment 0.232 -0.00529 -0.28 -0.2843 -1.0 1987424 ChemDiv2_006423 O=C(Cn1ncc2c(=O)oc3ccccc3c12)Nc4cccc(C#N)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 D24 compound treatment 0.465 0.228 12.24 12.2366 1.0 1987425 ChemDiv2_006424 COc1ccc2nc3oc(cc3cc2c1)C(=O)Nc4ccc(F)cc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E01 mock treatment 0.224 -0.0133 -0.71 -0.7142 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E02 mock treatment 0.234 -0.00329 -0.18 -0.1768 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E03 compound treatment 0.259 0.0217 1.17 1.1666 1.0 1987426 ChemDiv2_006425 CCN1CCN(CC1)C(=O)c2cc(C)nn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E04 compound treatment 0.361 0.124 6.65 6.6479 1.0 1987427 ChemDiv2_006426 CCOc1ccc(cc1)N(CC(=O)N2CCN(CC2)c3ccc(F)cc3)S(=O)(=O)c4c(C)noc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E05 compound treatment 0.476 0.239 12.83 12.8278 1.0 1987428 ChemDiv2_006427 CN1CCN(CC1)C(=O)c2ccc3c(c2)N(Cc4ccccc4F)C(=O)c5ccccc5S3(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E06 compound treatment 0.26 0.0227 1.22 1.2204 1.0 1987429 ChemDiv2_006428 COc1cc(OC)c(NS(=O)(=O)c2coc(c2)C(=O)N)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E07 compound treatment 0.296 0.0587 3.15 3.1549 1.0 1987430 ChemDiv2_006429 CN(CCC#N)C(=O)c1ccc2S(=O)c3ccccc3C(=O)N(Cc4ccc(F)cc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E08 compound treatment 0.307 0.0697 3.75 3.7461 1.0 1987431 ChemDiv2_006430 CCOC(=O)c1cn(CC(=O)Nc2cccc(F)c2)nn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E09 compound treatment 0.391 0.154 8.26 8.26 1.0 1987432 ChemDiv2_006431 CN(Cc1ccccc1)C(=O)CS(=O)(=O)Cc2nc(oc2C)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E10 compound treatment 0.23 -0.00729 -0.39 -0.3918 -1.0 1987433 ChemDiv2_006432 CCOC(=O)CSc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3cc(C)ccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E11 compound treatment 0.275 0.0377 2.03 2.0264 1.0 1987434 ChemDiv2_006433 CC(C)NC(=O)CS(=O)Cc1nc(oc1C)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E12 compound treatment 0.43 0.193 10.36 10.3558 1.0 1987435 ChemDiv2_006434 Clc1ccc2nc3CCCCc3c(SCC(=O)NCc4ccco4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E13 compound treatment 0.442 0.205 11.0 11.0007 1.0 1987436 ChemDiv2_006435 Cc1oc(nc1CSCC(=O)NCc2ccccc2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E14 compound treatment 0.317 0.0797 4.28 4.2834 1.0 1987437 ChemDiv2_006436 O=C(CSc1c2CCCCc2nc3ccccc13)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E15 compound treatment 0.271 0.0337 1.81 1.8115 1.0 1987438 ChemDiv2_006437 Cc1oc(nc1CN2CCC(CC2)C(=O)NCCC3=CCCCC3)c4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E16 compound treatment 0.482 0.245 13.15 13.1502 1.0 1987439 ChemDiv2_006438 Cn1c(cc2c(=O)[nH]c3ccccc3c12)C(=O)NCc4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E17 compound treatment 0.268 0.0307 1.65 1.6503 1.0 1987440 ChemDiv2_006439 Cc1oc(nc1CN2CCC(CC2)C(=O)N3CCc4ccccc4C3)c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E18 compound treatment 0.437 0.2 10.73 10.732 1.0 1987441 ChemDiv2_006440 N=c1oc2c3CCCN4CCCc(cc2cc1C(=O)Nc5ccccc5)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E19 compound treatment 0.262 0.0247 1.33 1.3278 1.0 1987442 ChemDiv2_006441 CC1CCN(CCCNC(=O)c2ccc(CS(=O)(=O)c3ccccc3C)o2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E20 compound treatment 0.337 0.0997 5.36 5.3582 1.0 1987443 ChemDiv2_006442 CN(CC(=O)N(C)c1ccc(Br)cc1)S(=O)(=O)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E21 compound treatment 0.352 0.115 6.16 6.1643 1.0 1987444 ChemDiv2_006443 Cc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E22 compound treatment 0.3 0.0627 3.37 3.3699 1.0 1987445 ChemDiv2_006444 CCOC(=O)N1CCN(CC1)C(=O)C(NS(=O)(=O)c2cccc3nsnc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E23 compound treatment 0.448 0.211 11.32 11.3231 1.0 1987446 ChemDiv2_006445 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 E24 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987447 ChemDiv2_006446 Cn1c(=O)n(C)c2nc(CN(Cc3ccccc3)Cc4ccccc4)n(CCCO)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F01 mock treatment 0.225 -0.0123 -0.66 -0.6605 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F02 mock treatment 0.236 -0.00129 -0.07 -0.0693 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F03 compound treatment 0.26 0.0227 1.22 1.2204 1.0 1987448 ChemDiv2_006447 CCn1c(CN2CCCCC2C)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F04 compound treatment 0.27 0.0327 1.76 1.7577 1.0 1987449 ChemDiv2_006448 COc1cccc(NC(=O)Cn2ncc3c(=O)oc4ccccc4c23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F05 compound treatment 0.36 0.123 6.59 6.5942 1.0 1987450 ChemDiv2_006449 Cc1cc(NC(=O)c2cnc3sccn3c2=O)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F06 compound treatment 0.385 0.148 7.94 7.9376 1.0 1987451 ChemDiv2_006450 CCOC(=O)CCc1c(C)c2c(C)nn(c3ccccc3)c2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F07 compound treatment 0.42 0.183 9.82 9.8184 1.0 1987452 ChemDiv2_006451 O=C1N(CC2N(CCc3ccccc23)S(=O)(=O)c4c[nH]cn4)C(=O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F08 compound treatment 0.264 0.0267 1.44 1.4353 1.0 1987453 ChemDiv2_006452 COc1ccc(NC(=O)c2cnn3c(O)cc(nc23)C4CCN(CC4)C(=O)OC(C)(C)C)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F09 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987454 ChemDiv2_006453 O=S(=O)(N1CCc2ccccc12)c3c[nH]cn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F10 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987455 ChemDiv2_006454 Fc1cccc(NC(=O)C2C3OC4(CN(CCCN5CCOCC5)C(=O)C24)C=C3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F11 compound treatment 0.463 0.226 12.13 12.1292 1.0 1987456 ChemDiv2_006455 COc1cccc(c1)c2nn(C)c3sc(cc23)C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F12 compound treatment 0.365 0.128 6.86 6.8629 1.0 1987457 ChemDiv2_006456 O=C(N1CCOCC1)c2cccc(c2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F13 compound treatment 0.454 0.217 11.65 11.6455 1.0 1987458 ChemDiv2_006457 CCOC(=O)c1cccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3s2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F14 compound treatment 0.305 0.0677 3.64 3.6386 1.0 1987459 ChemDiv2_006458 CSc1cccc(Nc2cc(C(=O)NCCN3CCOCC3)c4ccccc4n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F15 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987460 ChemDiv2_006459 CCOC(=O)C1CCN(CC1)C(=O)c2cccc3CN(C4CCCCC4)C(=O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F16 compound treatment 0.462 0.225 12.08 12.0754 1.0 1987461 ChemDiv2_006460 Fc1ccccc1NS(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F17 compound treatment 0.275 0.0377 2.03 2.0264 1.0 1987462 ChemDiv2_006461 CCCN1Cc2cccc(C(=O)N3CCN(CC3)c4ccc(F)cc4)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F18 compound treatment 0.27 0.0327 1.76 1.7577 1.0 1987463 ChemDiv2_006462 CN1CCN(CCCNC(=O)c2ccc(CNS(=O)(=O)c3ccc(C)cc3)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F19 compound treatment 0.262 0.0247 1.33 1.3278 1.0 1987464 ChemDiv2_006463 COc1cc2nc(SCC(=O)NCc3ccco3)n4nc(CCn5nc(C)cc5C)nc4c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F20 compound treatment 0.234 -0.00329 -0.18 -0.1768 -1.0 1987465 ChemDiv2_006464 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)c3oc(=O)c4ccccc4c3c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F21 compound treatment 0.34 0.103 5.52 5.5194 1.0 1987466 ChemDiv2_006465 Cc1n[nH]c(C)c1S(=O)(=O)N(CC(=O)Nc2ccc(Br)cc2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F22 compound treatment 0.51 0.273 14.65 14.6548 1.0 1987467 ChemDiv2_006466 CCOc1ccc(CNC(=O)c2cc3cc4ccc(OC)cc4nc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F23 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987468 ChemDiv2_006467 O=C(Cn1ncc2c(=O)oc3ccccc3c12)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 F24 compound treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1987469 ChemDiv2_006468 COc1ccc(NC(=O)Cn2nnc(C(=O)NCc3ccc4OCOc4c3)c2N)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G01 mock treatment 0.24 0.00271 0.15 0.1456 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G02 mock treatment 0.232 -0.00529 -0.28 -0.2843 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G03 compound treatment 0.236 -0.00129 -0.07 -0.0693 -1.0 1987470 ChemDiv2_006469 Cc1cc(C(=O)N2CCOCC2)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G04 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987471 ChemDiv2_006470 CCOc1ccc(cc1)N(CC(=O)NC2CCCC2)S(=O)(=O)c3c(C)noc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G05 compound treatment 0.417 0.18 9.66 9.6572 1.0 1987472 ChemDiv2_006471 Cc1cccc(CN2C(=O)c3ccccc3S(=O)(=O)c4ccc(cc24)C(=O)NCCN5CCCC5)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G06 compound treatment 0.34 0.103 5.52 5.5194 1.0 1987473 ChemDiv2_006472 CC1CCC(CC1)NS(=O)(=O)c2ccc3N(CCc3c2)C(=O)CCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G07 compound treatment 0.323 0.0857 4.61 4.6059 1.0 1987474 ChemDiv2_006473 CC1CCCCN1CCNC(=O)c2ccc3S(=O)c4ccccc4C(=O)N(Cc5ccccc5F)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G08 compound treatment 0.296 0.0587 3.15 3.1549 1.0 1987475 ChemDiv2_006474 CCc1ccc(cc1)n2c(nc3ccccc3c2=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G09 compound treatment 0.342 0.105 5.63 5.6269 1.0 1987476 ChemDiv2_006475 Cc1oc(nc1CS(=O)(=O)CC(=O)Nc2c(C)cccc2C)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G10 compound treatment 0.247 0.00971 0.52 0.5218 1.0 1987477 ChemDiv2_006476 O=c1cc(Cc2nnc(SCc3ccccc3)n2c4ccccc4)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G11 compound treatment 0.335 0.0977 5.25 5.2507 1.0 1987478 ChemDiv2_006477 Cc1oc(nc1CS(=O)CC(=O)NCc2ccc(C)cc2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G12 compound treatment 0.341 0.104 5.57 5.5731 1.0 1987479 ChemDiv2_006478 CCC1CCCCN1C(=O)CSc2c3CCCc3nc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G13 compound treatment 0.379 0.142 7.62 7.6152 1.0 1987480 ChemDiv2_006479 Cc1oc(nc1CSCC(=O)N2CCOCC2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G14 compound treatment 0.266 0.0287 1.54 1.5428 1.0 1987481 ChemDiv2_006480 CCN1CCCC1CNC(=O)CSc2c3CCCCc3nc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G15 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987482 ChemDiv2_006481 Cc1oc(nc1CN2CCC(CC2)C(=O)NC3CCCCC3)c4cccc(Br)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G16 compound treatment 0.384 0.147 7.88 7.8839 1.0 1987483 ChemDiv2_006482 CCC1CCCCN1CCCNC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G17 compound treatment 0.258 0.0207 1.11 1.1129 1.0 1987484 ChemDiv2_006483 CC1CCCN(CCCNC(=O)c2ccc(CS(=O)(=O)c3c(Cl)cccc3Cl)o2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G18 compound treatment 0.276 0.0387 2.08 2.0802 1.0 1987485 ChemDiv2_006484 CCOC(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c3ccc(cc13)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G19 compound treatment 0.363 0.126 6.76 6.7554 1.0 1987486 ChemDiv2_006485 Cc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G20 compound treatment 0.413 0.176 9.44 9.4423 1.0 1987487 ChemDiv2_006486 O=C(NCC1COc2ccccc2O1)C(NS(=O)(=O)c3cccc4nsnc34)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G21 compound treatment 0.434 0.197 10.57 10.5708 1.0 1987488 ChemDiv2_006487 Cc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G22 compound treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1987489 ChemDiv2_006488 CCOC(=O)c1nn(c2ccc(F)cc2)c(=O)c3c(NC(=O)c4cc(OC)c(OC)c(OC)c4)scc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G23 compound treatment 0.401 0.164 8.8 8.7974 1.0 1987490 ChemDiv2_006489 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCC(CC3)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 G24 compound treatment 0.234 -0.00329 -0.18 -0.1768 -1.0 1987491 ChemDiv2_006490 Cn1c(=O)n(C)c2nc(CN3CCCCC3)n(CC(=O)N)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H01 mock treatment 0.241 0.00371 0.2 0.1994 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H02 mock treatment 0.238 7.1E-4 0.04 0.0381 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H03 compound treatment 0.257 0.0197 1.06 1.0592 1.0 1987492 ChemDiv2_006491 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)NC(C(C)C)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H04 compound treatment 0.492 0.255 13.69 13.6876 1.0 1987493 ChemDiv2_006492 O=C(Cn1ncc2c(=O)oc3ccccc3c12)Nc4ccc(Oc5ccccc5)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H05 compound treatment 0.288 0.0507 2.73 2.725 1.0 1987494 ChemDiv2_006493 O=C(Nc1ccccc1)c2cnc3sccn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H06 compound treatment 0.279 0.0417 2.24 2.2414 1.0 1987495 ChemDiv2_006494 OC(=O)Cc1cnc(o1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H07 compound treatment 0.236 -0.00129 -0.07 -0.0693 -1.0 1987496 ChemDiv2_006495 O=S(=O)(N1CCCCC1)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H08 compound treatment 0.253 0.0157 0.84 0.8442 1.0 1128390 ChemDiv2_006496 O=C1N(CCN2CCOCC2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H09 compound treatment 0.291 0.0537 2.89 2.8862 1.0 1987497 ChemDiv2_006497 CCN(c1ccccc1)S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H10 compound treatment 0.247 0.00971 0.52 0.5218 1.0 1987498 ChemDiv2_006498 CCOc1ccc(NC(=O)C2C3OC4(CN(C(C(C)C)C(=O)OC)C(=O)C24)C=C3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H11 compound treatment 0.28 0.0427 2.3 2.2951 1.0 1987499 ChemDiv2_006499 COc1ccc(cc1)n2nc(C(=O)N(C)c3ccc(OC)cc3OC)c4c5ccccc5n(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H12 compound treatment 0.375 0.138 7.4 7.4002 1.0 1987500 ChemDiv2_006500 CNC(=O)c1cccc(c1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H13 compound treatment 0.47 0.233 12.51 12.5053 1.0 1987501 ChemDiv2_006501 CC(C)CCNC(=O)c1cc2c(=O)[nH]c3ccccc3c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H14 compound treatment 0.262 0.0247 1.33 1.3278 1.0 1987502 ChemDiv2_006502 COc1ccc(Nc2cc(C(=O)NCC3CCCO3)c4ccccc4n2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H15 compound treatment 0.337 0.0997 5.36 5.3582 1.0 1987503 ChemDiv2_006503 COCCN1Cc2cccc(C(=O)NCC3CCN(CC(C)C)C3)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H16 compound treatment 0.487 0.25 13.42 13.4189 1.0 1987504 ChemDiv2_006504 CCc1ccc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)NC4CCCCC4)c(=O)c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H17 compound treatment 0.27 0.0327 1.76 1.7577 1.0 1987505 ChemDiv2_006505 CC(C)CN1CCC(CNC(=O)c2cccc3CN(Cc4cccnc4)C(=O)c32)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H18 compound treatment 0.293 0.0557 2.99 2.9937 1.0 1987506 ChemDiv2_006506 COc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)N3CCN(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H19 compound treatment 0.445 0.208 11.16 11.1619 1.0 1987507 ChemDiv2_006507 CC(=O)N1CCCc2cc(ccc12)S(=O)(=O)N3CCC(=CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H20 compound treatment 0.241 0.00371 0.2 0.1994 1.0 1738809 ChemDiv2_006508 O=C(N1CCOCC1)c2oc(=O)c3ccccc3c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H21 compound treatment 0.423 0.186 9.98 9.9796 1.0 1987508 ChemDiv2_006509 COc1cccc(c1)N2CCN(CC2)C(=O)CN(c3ccc(C)cc3)S(=O)(=O)c4c(C)n[nH]c4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H22 compound treatment 0.557 0.32 17.18 17.1805 1.0 1987509 ChemDiv2_006510 CCc1ccccc1NC(=O)c2cc3cc4ccc(OC)cc4nc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H23 compound treatment 0.28 0.0427 2.3 2.2951 1.0 1987510 ChemDiv2_006511 O=C(Cn1ncc2c(=O)oc3ccccc3c12)NCCCN4CCCC4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 H24 compound treatment 0.239 0.00171 0.09 0.0919 1.0 1987511 ChemDiv2_006512 Nc1c(nnn1CC(=O)Nc2ccccc2)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I01 mock treatment 0.223 -0.0143 -0.77 -0.7679 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I02 mock treatment 0.232 -0.00529 -0.28 -0.2843 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I03 compound treatment 0.238 7.1E-4 0.04 0.0381 1.0 1987512 ChemDiv2_006513 Cc1cc(C(=O)NC2CC2)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I04 compound treatment 0.296 0.0587 3.15 3.1549 1.0 1987513 ChemDiv2_006514 COc1ccc(cc1)N(CC(=O)N2CCc3ccccc23)S(=O)(=O)c4c(C)n[nH]c4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I05 compound treatment 0.454 0.217 11.65 11.6455 1.0 1987514 ChemDiv2_006515 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc3c(c2)N(CC)C(=O)c4ccccc4S3(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I06 compound treatment 0.342 0.105 5.63 5.6269 1.0 1987515 ChemDiv2_006516 CC1CCCN(C1)S(=O)(=O)c2ccc3N(CCc3c2)C(=O)CCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I07 compound treatment 0.476 0.239 12.83 12.8278 1.0 1987516 ChemDiv2_006517 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc3S(=O)c4ccccc4C(=O)N(Cc5ccccc5F)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I08 compound treatment 0.313 0.0757 4.07 4.0685 1.0 1987517 ChemDiv2_006518 O=C(N1CCN(CC1)c2nc3ccccc3c(=O)n2c4ccccc4)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I09 compound treatment 0.347 0.11 5.9 5.8956 1.0 1987518 ChemDiv2_006519 Cc1oc(nc1CS(=O)CC(=O)N2CCc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I10 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987519 ChemDiv2_006520 O=C(CSc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3ccccc3)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I11 compound treatment 0.276 0.0387 2.08 2.0802 1.0 1987520 ChemDiv2_006521 Cc1oc(nc1CS(=O)CC(=O)N2CCCCC2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I12 compound treatment 0.305 0.0677 3.64 3.6386 1.0 1987521 ChemDiv2_006522 COc1cccc(NC(=O)CSc2c3CCCc3nc4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I13 compound treatment 0.406 0.169 9.07 9.0661 1.0 1987522 ChemDiv2_006523 CCN1CCN(CC1)C(=O)CSCc2nc(oc2C)c3ccc(CC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I14 compound treatment 0.278 0.0407 2.19 2.1877 1.0 1987523 ChemDiv2_006524 CC(C)NC(=O)CSc1c2CCCCc2nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I15 compound treatment 0.35 0.113 6.06 6.0568 1.0 1987524 ChemDiv2_006525 CCc1ccc(cc1)c2nc(CN3CCC(CC3)C(=O)NCc4cccs4)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I16 compound treatment 0.342 0.105 5.63 5.6269 1.0 1987525 ChemDiv2_006526 CN1CCN(CCCNC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I17 compound treatment 0.268 0.0307 1.65 1.6503 1.0 1987526 ChemDiv2_006527 Clc1cccc(Cl)c1S(=O)(=O)Cc2ccc(o2)C(=O)NCCN3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I18 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987527 ChemDiv2_006528 CC(C)(C)C(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c3ccc(cc13)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I19 compound treatment 0.371 0.134 7.19 7.1853 1.0 1987528 ChemDiv2_006529 CCCCN(C)C(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I20 compound treatment 0.269 0.0317 1.7 1.704 1.0 1987529 ChemDiv2_006530 O=C(C(Cc1ccccc1)NS(=O)(=O)c2cccc3nsnc23)N4CCN(CC4)C(=O)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I21 compound treatment 0.361 0.124 6.65 6.6479 1.0 1987530 ChemDiv2_006531 Cc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I22 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987531 ChemDiv2_006532 CCOC(=O)c1nn(c2ccccc2)c(=O)c3c(NC(=O)C(C)C)scc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I23 compound treatment 0.332 0.0947 5.09 5.0895 1.0 1987532 ChemDiv2_006533 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 I24 compound treatment 0.246 0.00871 0.47 0.468 1.0 1987533 ChemDiv2_006534 Cn1c(=O)n(C)c2nc(CN(Cc3ccccc3)Cc4ccccc4)n(CC(=O)N)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J01 mock treatment 0.232 -0.00529 -0.28 -0.2843 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J02 mock treatment 0.251 0.0137 0.74 0.7367 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J03 compound treatment 0.345 0.108 5.79 5.7881 1.0 1987534 ChemDiv2_006535 CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)NC(C(C)C)C(=O)N3CCN(CC3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J04 compound treatment 0.265 0.0277 1.49 1.4891 1.0 1987535 ChemDiv2_006536 O=C(Cn1ncc2c(=O)oc3ccccc3c12)Nc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J05 compound treatment 0.276 0.0387 2.08 2.0802 1.0 1987536 ChemDiv2_006537 O=C(N(Cc1ccccc1)c2ccccn2)c3cnc4sccn4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J06 compound treatment 0.254 0.0167 0.9 0.8979 1.0 1987537 ChemDiv2_006538 CCCN1Cc2cccc(c3nc(C)c(o3)C(=O)OCC)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J07 compound treatment 0.262 0.0247 1.33 1.3278 1.0 1987538 ChemDiv2_006539 CN(c1cccc(C)c1)S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J08 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987539 ChemDiv2_006540 CCOC(=O)CN1CC2(OC3C=C2)C(C3C(=O)N4CCCC4)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J09 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987540 ChemDiv2_006541 Clc1cccc(NS(=O)(=O)c2c[nH]cn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J10 compound treatment 0.244 0.00671 0.36 0.3606 1.0 1150387 ChemDiv2_006542 CCOC(=O)CN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J11 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987541 ChemDiv2_006543 COc1ccc(cc1)n2nc(C(=O)N3CCCCC3C)c4c5ccccc5n(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J12 compound treatment 0.475 0.238 12.77 12.774 1.0 1987542 ChemDiv2_006544 O=C(NCc1ccccc1)c2cccc(c2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J13 compound treatment 0.482 0.245 13.15 13.1502 1.0 1987543 ChemDiv2_006545 CCc1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J14 compound treatment 0.258 0.0207 1.11 1.1129 1.0 1987544 ChemDiv2_006546 COc1ccc(Nc2cc(C(=O)NCCCN3CCOCC3)c4ccccc4n2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J15 compound treatment 0.431 0.194 10.41 10.4096 1.0 1987545 ChemDiv2_006547 CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cccc3CN(CCOC)C(=O)c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J16 compound treatment 0.473 0.236 12.67 12.6665 1.0 1987546 ChemDiv2_006548 CCc1ccccc1NS(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4cccnc4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J17 compound treatment 0.392 0.155 8.31 8.3138 1.0 1987547 ChemDiv2_006549 CCOc1ccc(CCNC(=O)c2cccc3CN(Cc4cccnc4)C(=O)c32)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J18 compound treatment 0.288 0.0507 2.73 2.725 1.0 1987548 ChemDiv2_006550 COc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)NCCCN3CC(C)CC(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J19 compound treatment 0.259 0.0217 1.17 1.1666 1.0 1987549 ChemDiv2_006551 CC(=O)N1CCCc2cc(ccc12)S(=O)(=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J20 compound treatment 0.282 0.0447 2.4 2.4026 1.0 1987550 ChemDiv2_006552 O=C(N1CCN(CC1)C(=O)c2oc(=O)c3ccccc3c2c4ccccc4)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J21 compound treatment 0.376 0.139 7.45 7.454 1.0 1987551 ChemDiv2_006553 CCOC(=O)c1cccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3c(C)n[nH]c3C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J22 compound treatment 0.582 0.345 18.52 18.524 1.0 1987552 ChemDiv2_006554 CCCCN(CC)C(=O)c1cc2cc3ccc(OC)cc3nc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J23 compound treatment 0.277 0.0397 2.13 2.1339 1.0 1987553 ChemDiv2_006555 C=CCN(C(=O)Cn1ncc2c(=O)oc3ccccc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 J24 compound treatment 0.239 0.00171 0.09 0.0919 1.0 1987554 ChemDiv2_006556 CCOC(=O)C(C)(C)Sc1nc(O)c2cnn(c3ccc(C)c(C)c3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K01 mock treatment 0.232 -0.00529 -0.28 -0.2843 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K02 mock treatment 0.238 7.1E-4 0.04 0.0381 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K03 compound treatment 0.247 0.00971 0.52 0.5218 1.0 1987555 ChemDiv2_006557 CCN(CC)C(=O)c1ccc2S(=O)CC(=O)N(Cc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K04 compound treatment 0.261 0.0237 1.27 1.2741 1.0 1987556 ChemDiv2_006558 COc1ccc(cc1)N(CC(=O)N2CCc3ccccc23)S(=O)(=O)c4c(C)nn(C)c4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K05 compound treatment 0.311 0.0737 3.96 3.961 1.0 1987557 ChemDiv2_006559 CCN1C(=O)c2ccccc2S(=O)c3ccc(cc13)C(=O)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K06 compound treatment 0.401 0.164 8.8 8.7974 1.0 1987558 ChemDiv2_006560 OC(=O)CCCC(=O)N1CCc2cc(ccc12)S(=O)(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K07 compound treatment 0.327 0.0897 4.82 4.8208 1.0 1987559 ChemDiv2_006561 CC1CN(CCN1c2cccc(C)c2)C(=O)CS(=O)(=O)Cc3nc(oc3C)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K08 compound treatment 0.24 0.00271 0.15 0.1456 1.0 1159794 ChemDiv2_006562 O=c1n(c2ccccc2)c(nc3ccccc13)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K09 compound treatment 0.342 0.105 5.63 5.6269 1.0 1987560 ChemDiv2_006563 COc1ccc(cc1OC)c2nc(CS(=O)CC(=O)NC3CCCc4ccccc34)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K10 compound treatment 0.264 0.0267 1.44 1.4353 1.0 1987561 ChemDiv2_006564 O=C(CSc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3ccccc3)Nc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K11 compound treatment 0.443 0.206 11.05 11.0544 1.0 1987562 ChemDiv2_006565 Cc1ccsc1c2nc(CSCC(=O)NCc3ccc4OCOc4c3)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K12 compound treatment 0.393 0.156 8.37 8.3675 1.0 1987563 ChemDiv2_006566 Fc1ccccc1NC(=O)CSc2c3CCCc3nc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K13 compound treatment 0.529 0.292 15.68 15.6759 1.0 1987564 ChemDiv2_006567 CSc1ccc(cc1)c2nc(CSCC(=O)N(C)Cc3ccccc3)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K14 compound treatment 0.508 0.271 14.55 14.5474 1.0 1987565 ChemDiv2_006568 Cc1cccc(NC(=O)CSc2c3CCCCc3nc4ccccc24)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K15 compound treatment 0.254 0.0167 0.9 0.8979 1.0 1987566 ChemDiv2_006569 CCc1ccc(cc1)c2nc(CN3CCC(CC3)C(=O)NC(C)C)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K16 compound treatment 0.287 0.0497 2.67 2.6713 1.0 1987567 ChemDiv2_006570 Cn1c(cc2c(=O)[nH]c3ccccc3c12)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K17 compound treatment 0.282 0.0447 2.4 2.4026 1.0 1987568 ChemDiv2_006571 Clc1cccc(Cl)c1S(=O)(=O)Cc2ccc(o2)C(=O)NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K18 compound treatment 0.39 0.153 8.21 8.2063 1.0 1987569 ChemDiv2_006572 Cc1cc(NC(=O)Cn2c(=O)n(CC3CCCO3)c(=O)c4ccc(cc24)C(=O)NC5CCCCC5)[nH]n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K19 compound treatment 0.357 0.12 6.43 6.4329 1.0 1987570 ChemDiv2_006573 Cc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)N3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K20 compound treatment 0.337 0.0997 5.36 5.3582 1.0 1987571 ChemDiv2_006574 COc1cccc(CNC(=O)C(NS(=O)(=O)c2cccc3nsnc23)c4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K21 compound treatment 0.268 0.0307 1.65 1.6503 1.0 1987572 ChemDiv2_006575 O=C(NCc1ccccc1)c2ccc(CS(=O)(=O)c3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K22 compound treatment 0.398 0.161 8.64 8.6362 1.0 1987573 ChemDiv2_006576 OC1=C2C(Sc3ccccc3N=C2c4ccccc14)c5ccc(O)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K23 compound treatment 0.312 0.0747 4.01 4.0147 1.0 1987574 ChemDiv2_006577 CN(Cc1ccccc1)S(=O)(=O)c2ccc3n(C)c(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 K24 compound treatment 0.234 -0.00329 -0.18 -0.1768 -1.0 1987575 ChemDiv2_006578 CCOC(=O)Cn1c(CN2CC(C)OC(C)C2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L01 mock treatment 0.246 0.00871 0.47 0.468 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L02 mock treatment 0.254 0.0167 0.9 0.8979 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L03 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987576 ChemDiv2_006579 COc1ccc(Cl)cc1NC(=O)c2cnc3scc(C)n3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L04 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987577 ChemDiv2_006580 OC(=O)C1C2OC3(CN(CC4CCCO4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L05 compound treatment 0.255 0.0177 0.95 0.9517 1.0 1987578 ChemDiv2_006581 CC1CCCCN1C(=O)c2cnc3sccn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L06 compound treatment 0.326 0.0887 4.77 4.7671 1.0 1987579 ChemDiv2_006582 NC(=O)c1cccc2CN(C3CCCCC3)C(=O)c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L07 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987580 ChemDiv2_006583 O=S(=O)(Nc1ccc2OCCOc2c1)c3c[nH]cn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L08 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987581 ChemDiv2_006584 CCOC(=O)CN1CC2(OC3C=C2)C(C3C(=O)N4CCN(CC4)c5ccc(F)cc5)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L09 compound treatment 0.279 0.0417 2.24 2.2414 1.0 1987582 ChemDiv2_006585 CCCN1CCN(CCCNC(=O)c2cc3c(nn(C)c3s2)c4ccc(OC)c(OC)c4)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L10 compound treatment 0.263 0.0257 1.38 1.3816 1.0 1774294 ChemDiv2_006586 Cc1[nH]c(=O)[nH]c1CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L11 compound treatment 0.277 0.0397 2.13 2.1339 1.0 1987583 ChemDiv2_006587 COc1ccc(cc1)n2nc(C(=O)N3CCCC3)c4c5ccccc5n(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L12 compound treatment 0.339 0.102 5.47 5.4657 1.0 1987584 ChemDiv2_006588 CC1CCCCC1NC(=O)c2cccc(c2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L13 compound treatment 0.474 0.237 12.72 12.7203 1.0 1987585 ChemDiv2_006589 Fc1ccc(CNC(=O)c2cc3c(=O)[nH]c4ccccc4c3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L14 compound treatment 0.254 0.0167 0.9 0.8979 1.0 1788995 ChemDiv2_006590 COc1ccc(Nc2cc(C(=O)N3CCCCC3)c4ccccc4n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L15 compound treatment 0.448 0.211 11.32 11.3231 1.0 1987586 ChemDiv2_006591 COCCN1Cc2cccc(C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L16 compound treatment 0.405 0.168 9.01 9.0124 1.0 1987587 ChemDiv2_006592 COc1cccc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCCCC4)c(=O)c3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L17 compound treatment 0.246 0.00871 0.47 0.468 1.0 1987588 ChemDiv2_006593 O=C(N1CCN(CC1)c2ccccc2)c3cccc4CN(Cc5cccnc5)C(=O)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L18 compound treatment 0.329 0.0917 4.93 4.9283 1.0 1987589 ChemDiv2_006594 COc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)NCCN3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L19 compound treatment 0.277 0.0397 2.13 2.1339 1.0 1987590 ChemDiv2_006595 CC(=O)N1CCCc2cc(ccc12)S(=O)(=O)Nc3cc(C)[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L20 compound treatment 0.383 0.146 7.83 7.8301 1.0 1987591 ChemDiv2_006596 CCCN1CCN(CC1)C(=O)c2oc(=O)c3ccccc3c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L21 compound treatment 0.373 0.136 7.29 7.2928 1.0 1987592 ChemDiv2_006597 Cc1noc(C)c1S(=O)(=O)Nc2ccc(cc2)C(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L22 compound treatment 0.547 0.31 16.64 16.6432 1.0 1987593 ChemDiv2_006598 COc1ccc2cc3cc(oc3nc2c1)C(=O)NCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L23 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987594 ChemDiv2_006599 CCN(C(=O)Cn1ncc2c(=O)oc3ccccc3c12)c4cc(OC)ccc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 L24 compound treatment 0.224 -0.0133 -0.71 -0.7142 -1.0 1987595 ChemDiv2_006600 Cc1ccc(cc1)n2ncc3c(O)nc(SCC(=O)NCc4ccco4)nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M01 mock treatment 0.231 -0.00629 -0.34 -0.338 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M02 mock treatment 0.24 0.00271 0.15 0.1456 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M03 compound treatment 0.499 0.262 14.06 14.0637 1.0 1987596 ChemDiv2_006601 CCN1CCCC1CNC(=O)c2ccc3c(c2)N(Cc4ccccc4)C(=O)c5ccccc5S3(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M04 compound treatment 0.238 7.1E-4 0.04 0.0381 1.0 1987597 ChemDiv2_006602 Cc1nn(C)c(C)c1S(=O)(=O)N(CC(=O)Nc2ccc(C)c(C)c2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M05 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987598 ChemDiv2_006603 O=C(NCc1ccccc1)c2ccc3S(=O)c4ccccc4C(=O)N(Cc5ccccc5)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M06 compound treatment 0.428 0.191 10.25 10.2483 1.0 1987599 ChemDiv2_006604 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)NCCN3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M07 compound treatment 0.305 0.0677 3.64 3.6386 1.0 1987600 ChemDiv2_006605 Cc1oc(nc1CS(=O)(=O)CC(=O)N2CCc3ccccc3C2)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M08 compound treatment 0.257 0.0197 1.06 1.0592 1.0 1987601 ChemDiv2_006606 CCOC(=O)C(C)Sc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M09 compound treatment 0.263 0.0257 1.38 1.3816 1.0 1987602 ChemDiv2_006607 Cc1oc(nc1CS(=O)CC(=O)NCCN2CCCC2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M10 compound treatment 0.271 0.0337 1.81 1.8115 1.0 1987603 ChemDiv2_006608 O=C(CSc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3ccccc3)N4CCCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M11 compound treatment 0.372 0.135 7.24 7.239 1.0 1987604 ChemDiv2_006609 Cc1ccsc1c2nc(CSCC(=O)N3CCC4(CC3)OCCO4)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M12 compound treatment 0.255 0.0177 0.95 0.9517 1.0 1987605 ChemDiv2_006610 Cn1nc(c2ccc(Cl)cc2)c3cc(sc13)C(=O)Nc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M13 compound treatment 0.313 0.0757 4.07 4.0685 1.0 1987606 ChemDiv2_006611 Cc1oc(nc1CSCC(=O)NC2CC2)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M14 compound treatment 0.37 0.133 7.13 7.1315 1.0 1987607 ChemDiv2_006612 Cn1nc(c2ccccc2F)c3cc(sc13)C(=O)NCc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M15 compound treatment 0.269 0.0317 1.7 1.704 1.0 1987608 ChemDiv2_006613 CCc1ccc(cc1)c2nc(CN3CCC(CC3)C(=O)NCc4ccco4)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M16 compound treatment 0.342 0.105 5.63 5.6269 1.0 1987609 ChemDiv2_006614 Cn1c(cc2c(=O)[nH]c3ccccc3c12)C(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M17 compound treatment 0.416 0.179 9.6 9.6035 1.0 1987610 ChemDiv2_006615 CCOC(=O)N1CCN(CC1)C(=O)c2ccc(CS(=O)(=O)c3c(Cl)cccc3Cl)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M18 compound treatment 0.275 0.0377 2.03 2.0264 1.0 1987611 ChemDiv2_006616 Fc1ccc(NC(=O)Cn2c(=O)n(CC3CCCO3)c(=O)c4ccc(cc24)C(=O)NC5CCCCC5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M19 compound treatment 0.372 0.135 7.24 7.239 1.0 1987612 ChemDiv2_006617 CCC(C)NC(=O)c1ccc(CS(=O)(=O)c2ccc(OC)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M20 compound treatment 0.261 0.0237 1.27 1.2741 1.0 1987613 ChemDiv2_006618 COc1ccccc1CNC(=O)C(NS(=O)(=O)c2cccc3nsnc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M21 compound treatment 0.25 0.0127 0.68 0.683 1.0 1987614 ChemDiv2_006619 O=C(N1CCOCC1)c2ccc(CS(=O)(=O)c3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M22 compound treatment 0.345 0.108 5.79 5.7881 1.0 1987615 ChemDiv2_006620 OC1=C2C(Sc3ccccc3N=C2c4ccccc14)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M23 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987616 ChemDiv2_006621 CSc1cccc(NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)c3c(C)noc3C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 M24 compound treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1987617 ChemDiv2_006622 COC(=O)Cn1c(CN2CCN(CC2)C(=O)c3ccco3)nc4n(C)c(=O)n(C)c(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N01 mock treatment 0.239 0.00171 0.09 0.0919 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N02 mock treatment 0.241 0.00371 0.2 0.1994 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N03 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987618 ChemDiv2_006623 COc1ccc(NC(=O)c2cnc3scc(C)n3c2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N04 compound treatment 0.277 0.0397 2.13 2.1339 1.0 1987619 ChemDiv2_006624 COCCN1Cc2cccc(C(=O)Nc3cccnc3)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N05 compound treatment 0.244 0.00671 0.36 0.3606 1.0 1987620 ChemDiv2_006625 Cc1c(NC(=O)C2CCN(CC2)S(=O)(=O)c3c[nH]cn3)c(=O)n(c4ccccc4)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N06 compound treatment 0.272 0.0347 1.87 1.8652 1.0 1987621 ChemDiv2_006626 Oc1cc(nc2c(cnn12)C(=O)NCc3ccco3)C4CCNCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N07 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987622 ChemDiv2_006627 Cc1ccc(CCNS(=O)(=O)c2c[nH]cn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N08 compound treatment 0.262 0.0247 1.33 1.3278 1.0 1987623 ChemDiv2_006628 CCOC(=O)CN1CC2(OC3C=C2)C(C3C(=O)Nc4ccc5OCOc5c4)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N09 compound treatment 0.245 0.00771 0.41 0.4143 1.0 1987624 ChemDiv2_006629 COc1ccc(cc1OC)c2nn(C)c3sc(cc23)C(=O)NCCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N10 compound treatment 0.428 0.191 10.25 10.2483 1.0 1987625 ChemDiv2_006630 Cc1n[nH]c2C(=O)NC(c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N11 compound treatment 0.247 0.00971 0.52 0.5218 1.0 1987626 ChemDiv2_006631 COc1ccc(cc1)n2nc(C(=O)N(C)Cc3ccccc3)c4c5ccccc5n(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N12 compound treatment 0.359 0.122 6.54 6.5404 1.0 1987627 ChemDiv2_006632 CN(Cc1ccco1)C(=O)c2ccc(cc2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N13 compound treatment 0.363 0.126 6.76 6.7554 1.0 1987628 ChemDiv2_006633 CN(Cc1ccccc1)C(=O)c2cc3c(=O)[nH]c4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N14 compound treatment 0.279 0.0417 2.24 2.2414 1.0 1987629 ChemDiv2_006634 CNC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)Nc3ccc(cc3)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N15 compound treatment 0.265 0.0277 1.49 1.4891 1.0 1987630 ChemDiv2_006635 COCCN1Cc2cccc(C(=O)Nc3ccc(OC)c(Cl)c3)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N16 compound treatment 0.356 0.119 6.38 6.3792 1.0 1987631 ChemDiv2_006636 COc1cccc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCc5ccccc45)c(=O)c3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N17 compound treatment 0.27 0.0327 1.76 1.7577 1.0 1987632 ChemDiv2_006637 O=C(NCc1cccnc1)c2cccc3CN(Cc4cccnc4)C(=O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N18 compound treatment 0.395 0.158 8.47 8.475 1.0 1987633 ChemDiv2_006638 CCOc1ccc(CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)NC(=O)C5CCNCC5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N19 compound treatment 0.44 0.203 10.89 10.8932 1.0 1987634 ChemDiv2_006639 CCOc1ccc(NC(=O)CCS(=O)(=O)c2ccc3N(CCCc3c2)C(=O)CC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N20 compound treatment 0.383 0.146 7.83 7.8301 1.0 1987635 ChemDiv2_006640 O=C(NC1CCCC1)c2oc(=O)c3ccccc3c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N21 compound treatment 0.242 0.00471 0.25 0.2531 1.0 1987636 ChemDiv2_006641 CCOc1ccc(CNC(=O)Cn2ncc3c(=O)oc4ccccc4c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N22 compound treatment 0.466 0.229 12.29 12.2904 1.0 1987637 ChemDiv2_006642 COc1ccc2nc3oc(cc3cc2c1)C(=O)NCCc4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N23 compound treatment 0.234 -0.00329 -0.18 -0.1768 -1.0 1987638 ChemDiv2_006643 CC1CCN(CCCNC(=O)Cn2ncc3c(=O)oc4ccccc4c23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 N24 compound treatment 0.251 0.0137 0.74 0.7367 1.0 1987639 ChemDiv2_006644 COC(=O)c1ccc(CSc2nc(O)c3cnn(c4ccc(C)cc4)c3n2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O01 mock treatment 0.226 -0.0113 -0.61 -0.6067 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O02 mock treatment 0.248 0.0107 0.58 0.5755 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O03 compound treatment 0.311 0.0737 3.96 3.961 1.0 1987640 ChemDiv2_006645 CCN(CC)C(=O)c1ccc2c(c1)N(Cc3ccccc3)C(=O)c4ccccc4S2(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O04 compound treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1987641 ChemDiv2_006646 CC(C)C(NS(=O)(=O)c1ccc2N(CCCc2c1)C(=O)C)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O05 compound treatment 0.244 0.00671 0.36 0.3606 1.0 1987642 ChemDiv2_006647 O=C(N1CCCCC1)c2ccc3S(=O)c4ccccc4C(=O)N(Cc5ccccc5)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O06 compound treatment 0.245 0.00771 0.41 0.4143 1.0 1987643 ChemDiv2_006648 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O07 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987644 ChemDiv2_006649 CC1CCCC(C)N1C(=O)CS(=O)(=O)Cc2nc(oc2C)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O08 compound treatment 0.255 0.0177 0.95 0.9517 1.0 1987645 ChemDiv2_006650 CCOc1ccc(cc1)n2c(Cc3cc(=O)[nH]c(=O)[nH]3)nnc2SCC(=O)Nc4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O09 compound treatment 0.263 0.0257 1.38 1.3816 1.0 1987646 ChemDiv2_006651 Cc1oc(nc1CS(=O)CC(=O)NC2CCCCC2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O10 compound treatment 0.245 0.00771 0.41 0.4143 1.0 1987647 ChemDiv2_006652 O=C(CSc1nnc(Cc2cc(=O)[nH]c(=O)[nH]2)n1c3ccccc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O11 compound treatment 0.259 0.0217 1.17 1.1666 1.0 1987648 ChemDiv2_006653 Cc1ccsc1c2nc(CSCC(=O)N3CCN(CC3)c4ccccc4)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O12 compound treatment 0.248 0.0107 0.58 0.5755 1.0 1987649 ChemDiv2_006654 Cn1nc(c2ccc(Cl)cc2)c3cc(sc13)C(=O)NCc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O13 compound treatment 0.265 0.0277 1.49 1.4891 1.0 1987650 ChemDiv2_006655 CC(NC(=O)CSCc1nc(oc1C)c2ccccc2C)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O14 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987651 ChemDiv2_006656 CC(NC(=O)c1cc2c(=O)[nH]c3ccccc3c2n1C)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O15 compound treatment 0.255 0.0177 0.95 0.9517 1.0 1987652 ChemDiv2_006657 Cc1oc(nc1CN2CCC(CC2)C(=O)NCC3CCCO3)c4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O16 compound treatment 0.387 0.15 8.05 8.0451 1.0 1987653 ChemDiv2_006658 Cn1c(cc2c(=O)[nH]c3ccccc3c12)C(=O)NCc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O17 compound treatment 0.288 0.0507 2.73 2.725 1.0 1987654 ChemDiv2_006659 COc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)NCCN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O18 compound treatment 0.263 0.0257 1.38 1.3816 1.0 1987655 ChemDiv2_006660 C=CCn1c(=O)n(CC(=O)NCc2ccco2)c3cc(ccc3c1=O)C(=O)NCc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O19 compound treatment 0.378 0.141 7.56 7.5614 1.0 1987656 ChemDiv2_006661 CCOC(=O)N1CCN(CC1)C(=O)c2ccc(CS(=O)(=O)c3ccc(OC)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O20 compound treatment 0.273 0.0357 1.92 1.919 1.0 1987657 ChemDiv2_006662 COc1ccc(OC)c(NC(=O)C(Cc2ccccc2)NS(=O)(=O)c3cccc4nsnc34)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O21 compound treatment 0.28 0.0427 2.3 2.2951 1.0 1987658 ChemDiv2_006663 O=C(N1CCN(CC1)c2ccccc2)c3ccc(CS(=O)(=O)c4ccccc4)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O22 compound treatment 0.257 0.0197 1.06 1.0592 1.0 1987659 ChemDiv2_006664 Cn1c(=O)n(C)c2nc(CN3CCc4ccccc4C3)n(CCCc5ccccc5)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O23 compound treatment 0.258 0.0207 1.11 1.1129 1.0 1987660 ChemDiv2_006665 CC(C)c1ccc(cc1)N(CC(=O)NCc2ccc(C)cc2)S(=O)(=O)c3c(C)noc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 O24 compound treatment 0.245 0.00771 0.41 0.4143 1.0 1987661 ChemDiv2_006666 Cc1cccc(Cn2c(CN3CCN(CC3)c4ccc(F)cc4)nc5n(C)c(=O)n(C)c(=O)c25)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P01 mock treatment 0.251 0.0137 0.74 0.7367 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P02 mock treatment 0.246 0.00871 0.47 0.468 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P03 compound treatment 0.229 -0.00829 -0.45 -0.4455 -1.0 1987662 ChemDiv2_006667 CCN(C(=O)c1cnc2scc(C)n2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P04 compound treatment 0.287 0.0497 2.67 2.6713 1.0 1987663 ChemDiv2_006668 CCOC(=O)CCc1c(C)n(CC)c2ncnn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P05 compound treatment 0.228 -0.00929 -0.5 -0.4992 -1.0 1987664 ChemDiv2_006669 CN(c1ccc(Br)cc1)S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P06 compound treatment 0.255 0.0177 0.95 0.9517 1.0 1987665 ChemDiv2_006670 COc1ccc(NC(=O)c2cnn3c(O)cc(nc23)C4CCNCC4)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P07 compound treatment 0.226 -0.0113 -0.61 -0.6067 -1.0 1987666 ChemDiv2_006671 CC1CN(CCN1c2cccc(C)c2)S(=O)(=O)c3c[nH]cn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P08 compound treatment 0.236 -0.00129 -0.07 -0.0693 -1.0 1987667 ChemDiv2_006672 CCOC(=O)CN1CC2(OC3C=C2)C(C3C(=O)NC4CCCCCC4)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P09 compound treatment 0.432 0.195 10.46 10.4633 1.0 1987668 ChemDiv2_006673 CCOC(=O)C1CCN(CC1)C(=O)c2cc3c(nn(C)c3s2)c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P10 compound treatment 0.26 0.0227 1.22 1.2204 1.0 1987669 ChemDiv2_006674 O=C1NC(c2c(n[nH]c12)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P11 compound treatment 0.249 0.0117 0.63 0.6293 1.0 1987670 ChemDiv2_006675 COc1cccc(CNC(=O)c2cc3c(=O)[nH]c4ccccc4c3s2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P12 compound treatment 0.243 0.00571 0.31 0.3068 1.0 1987671 ChemDiv2_006676 O=C(NCCN1CCCCCC1)c2ccc(cc2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P13 compound treatment 0.287 0.0497 2.67 2.6713 1.0 1987672 ChemDiv2_006677 CN(C1CCCCC1)C(=O)c2cc3c(=O)[nH]c4ccccc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P14 compound treatment 0.289 0.0517 2.78 2.7788 1.0 1987673 ChemDiv2_006678 Cc1cc(C)cc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4)c(=O)c3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P15 compound treatment 0.238 7.1E-4 0.04 0.0381 1.0 1987674 ChemDiv2_006679 COCCN1Cc2cccc(C(=O)N3CCN(CC3)c4ccccc4)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P16 compound treatment 0.388 0.151 8.1 8.0988 1.0 1987675 ChemDiv2_006680 COc1cccc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4)c(=O)c3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P17 compound treatment 0.244 0.00671 0.36 0.3606 1.0 1987676 ChemDiv2_006681 Fc1ccc(NC(=O)c2cccc3CN(Cc4ccccn4)C(=O)c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P18 compound treatment 0.237 -2.9E-4 -0.02 -0.0156 -1.0 1987677 ChemDiv2_006682 CS(=O)(=O)N1CCn2c(C1)nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P19 compound treatment 0.233 -0.00429 -0.23 -0.2306 -1.0 1987678 ChemDiv2_006683 O=C(NCc1cccnc1)C2CCCN(C2)S(=O)(=O)c3cccc4nsnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P20 compound treatment 0.221 -0.0163 -0.88 -0.8754 -1.0 1987679 ChemDiv2_006684 CCOc1ccc(cc1)n2c(C)nc3n(ncc3c2=O)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P21 compound treatment 0.224 -0.0133 -0.71 -0.7142 -1.0 1987680 ChemDiv2_006685 O=C(Cn1ncc2c(=O)oc3ccccc3c12)NCC4(CCCC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P22 compound treatment 0.52 0.283 15.19 15.1922 1.0 1987681 ChemDiv2_006686 COc1ccc2nc3oc(cc3cc2c1)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P23 compound treatment 0.257 0.0197 1.06 1.0592 1.0 1987682 ChemDiv2_006687 O=C(Cn1ncc2c(=O)oc3ccccc3c12)NCCCN4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1387 P24 compound treatment 0.231 -0.00629 -0.34 -0.338 -1.0 1987683 ChemDiv2_006688 CCOC(=O)C(C)Sc1nc(O)c2cnn(c3ccc(Cl)cc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A01 compound treatment 0.318 0.0831 4.47 4.4653 1.0 1987684 ChemDiv2_006689 CC1=C(C(=O)Nc2cc([nH]n2)c3cccc(F)c3)C4(CCCCC4)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A02 compound treatment 0.247 0.0121 0.65 0.6499 1.0 1987685 ChemDiv2_006690 COc1ccc(cc1)c2cc3c(cc(NC(=O)C)cc3n2C)S(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A03 compound treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1987686 ChemDiv2_006691 CCOc1ccc2OC3(CCCCC3)CC(SCC(=O)N4CCN(CC4)c5ncccn5)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A04 compound treatment 0.363 0.128 6.88 6.8835 1.0 1987687 ChemDiv2_006692 Cc1ccc(NC(=O)C2CCN(CC2)c3ccc(nn3)N4CCOCC4)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A05 compound treatment 0.237 0.00209 0.11 0.1125 1.0 1987688 ChemDiv2_006693 O=C(NCc1ccc2OCOc2c1)C3CCCN(C3)S(=O)(=O)c4c[nH]cn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A06 compound treatment 0.289 0.0541 2.91 2.9069 1.0 1987689 ChemDiv2_006694 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)NCCCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A07 compound treatment 0.24 0.00509 0.27 0.2737 1.0 1987690 ChemDiv2_006695 O=C(NCc1cccnc1)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A08 compound treatment 0.255 0.0201 1.08 1.0798 1.0 1987691 ChemDiv2_006696 COc1ccc2cc3c(N)nn(C(=O)c4cccnc4)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A09 compound treatment 0.48 0.245 13.17 13.1708 1.0 1987692 ChemDiv2_006697 Nc1c(nnn1Cc2ccc(Br)cc2F)C(=O)Nc3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A10 compound treatment 0.263 0.0281 1.51 1.5097 1.0 1987693 ChemDiv2_006698 COc1ccc2cc3c(N)nn(C(=O)C4Cc5ccccc5CN4S(=O)(=O)C)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A11 compound treatment 0.484 0.249 13.39 13.3858 1.0 1987694 ChemDiv2_006699 CCC(C)C(N1Cc2ccccc2C1=O)C(=O)Nc3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A12 compound treatment 0.226 -0.00891 -0.48 -0.4786 -1.0 1987695 ChemDiv2_006700 CN(CC(=O)N1CCCCC1)S(=O)(=O)c2ccc3n(C)c(=O)n(C)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A13 compound treatment 0.268 0.0331 1.78 1.7784 1.0 1987696 ChemDiv2_006701 Cc1nc2cc(nn2c(C)c1CCC(=O)NCc3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A14 compound treatment 0.404 0.169 9.09 9.0867 1.0 1987697 ChemDiv2_006702 CCN1CCN(CCCNC(=O)c2ccc3c(Cl)c4CCCCc4nc3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A15 compound treatment 0.333 0.0981 5.27 5.2714 1.0 1987698 ChemDiv2_006703 COc1ccccc1c2cc3nc(C)c(CCC(=O)Nc4ccc5OCCOc5c4)c(C)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A16 compound treatment 0.229 -0.00591 -0.32 -0.3174 -1.0 1987699 ChemDiv2_006704 CC(C)N(Cc1nc(no1)c2cccc(C)c2)C(=O)CCC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A17 compound treatment 0.251 0.0161 0.86 0.8648 1.0 1987700 ChemDiv2_006705 Cc1nc2ncnn2c(C)c1CCC(=O)NCCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A18 compound treatment 0.34 0.105 5.65 5.6475 1.0 1987701 ChemDiv2_006706 CC(C)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A19 compound treatment 0.225 -0.00991 -0.53 -0.5323 -1.0 1987702 ChemDiv2_006707 CC(C)CC(NS(=O)(=O)c1ccc2n(C)c(=O)oc2c1)C(=O)NC3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A20 compound treatment 0.227 -0.00791 -0.42 -0.4249 -1.0 1987703 ChemDiv2_006708 CC(C)(CNC(=O)c1oc(=O)c2ccccc2c1c3ccccc3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A21 compound treatment 0.234 -9.06E-4 -0.05 -0.0487 -1.0 1987704 ChemDiv2_006709 O=C(NCc1ccccc1)C(NS(=O)(=O)c2ccc3NC(=O)CCc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A22 compound treatment 0.37 0.135 7.26 7.2597 1.0 1987705 ChemDiv2_006710 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A23 mock treatment 0.225 -0.00991 -0.53 -0.5323 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 A24 mock treatment 0.237 0.00209 0.11 0.1125 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B01 compound treatment 0.211 -0.0239 -1.28 -1.2847 -1.0 1987706 ChemDiv2_006711 COc1ccc(cc1)c2nc(SCC(=O)N3CCCc4ccccc34)c5c(=O)n(C)c(=O)n(C)c5n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B02 compound treatment 0.28 0.0451 2.42 2.4232 1.0 1987707 ChemDiv2_006712 O=c1cc([nH]c(=O)n1c2ccccc2)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B03 compound treatment 0.263 0.0281 1.51 1.5097 1.0 1987708 ChemDiv2_006713 CCCN1Cc2cccc(C(=O)NCc3ccccc3)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B04 compound treatment 0.491 0.256 13.76 13.7619 1.0 1987709 ChemDiv2_006714 O=C(N1CCN(CC1)c2ccc(nn2)N3CCOCC3)c4cc5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B05 compound treatment 0.261 0.0261 1.4 1.4022 1.0 1987710 ChemDiv2_006715 COc1ccc(Cn2c(CCC(=O)Nc3ccccc3)nc4cccnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B06 compound treatment 0.518 0.283 15.21 15.2129 1.0 1987711 ChemDiv2_006716 CC(C)C(=O)Nc1ccc(cc1)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B07 compound treatment 0.33 0.0951 5.11 5.1101 1.0 1987712 ChemDiv2_006717 CN(C(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B08 compound treatment 0.587 0.352 18.92 18.9208 1.0 1987713 ChemDiv2_006718 Cc1c(nc2ncccn12)c3cccc(NC(=O)c4cccc(Cl)c4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B09 compound treatment 0.279 0.0441 2.37 2.3695 1.0 1987714 ChemDiv2_006719 CC(C)CCN(Cc1ccco1)C(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B10 compound treatment 0.357 0.122 6.56 6.5611 1.0 1987715 ChemDiv2_006720 COc1ccc(cc1)C2=NOC(C2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B11 compound treatment 0.285 0.0501 2.69 2.6919 1.0 1987716 ChemDiv2_006721 CC(C)NC(=O)c1cc(C)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B12 compound treatment 0.344 0.109 5.86 5.8625 1.0 1987717 ChemDiv2_006722 Fc1ccc(cc1)C2=NOC(C2)C(=O)Nc3ccc(C#N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B13 compound treatment 0.249 0.0141 0.76 0.7574 1.0 1987718 ChemDiv2_006723 Cc1noc(C(=O)N2CCCC2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B14 compound treatment 0.284 0.0491 2.64 2.6382 1.0 1987719 ChemDiv2_006724 COc1ccc(OC)c(c1)C2=NOC(C2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B15 compound treatment 0.338 0.103 5.54 5.54 1.0 1987720 ChemDiv2_006725 Cc1ccc(CNC(=O)c2cc3c(C)nc4ccccc4c3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B16 compound treatment 0.368 0.133 7.15 7.1522 1.0 1987721 ChemDiv2_006726 CCOc1ccccc1NC(=O)Cn2cnc3n(Cc4ccc(F)cc4)nnc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B17 compound treatment 0.242 0.00709 0.38 0.3812 1.0 1987722 ChemDiv2_006727 Fc1ccc(Cn2c(=O)cc([nH]c2=O)N3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B18 compound treatment 0.299 0.0641 3.44 3.4443 1.0 1987723 ChemDiv2_006728 CCC(C(=O)OC)n1cnc2n(Cc3ccc(Cl)cc3)nnc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B19 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1987724 ChemDiv2_006729 Clc1ccc(cc1)n2c(=O)cc([nH]c2=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B20 compound treatment 0.246 0.0111 0.6 0.5962 1.0 1987725 ChemDiv2_006730 COc1ccc(cc1)n2nnc3c(=O)n(Cc4ccc(C)cc4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B21 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1987726 ChemDiv2_006731 Cc1ccc(Cl)cc1n2c(=O)cc([nH]c2=O)N3CCN(CC3)C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B22 compound treatment 0.237 0.00209 0.11 0.1125 1.0 1987727 ChemDiv2_006732 O=C(Cn1ncc2c(=O)oc3ccccc3c12)N(Cc4ccco4)C5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B23 mock treatment 0.225 -0.00991 -0.53 -0.5323 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 B24 mock treatment 0.221 -0.0139 -0.75 -0.7473 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C01 compound treatment 0.236 0.00109 0.06 0.0588 1.0 1987728 ChemDiv2_006733 CN(CCC#N)C(=O)C1=C(C)C(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C02 compound treatment 0.245 0.0101 0.54 0.5424 1.0 1987729 ChemDiv2_006734 CC(C)CC(NS(=O)(=O)c1ccc2nc(C)sc2c1)C(=O)N3CCn4c3nc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C03 compound treatment 0.578 0.343 18.44 18.4371 1.0 1987730 ChemDiv2_006735 COc1ccc(cc1)c2cn3c(C)c(sc3n2)C(=O)Nc4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C04 compound treatment 0.285 0.0501 2.69 2.6919 1.0 1987731 ChemDiv2_006736 Cn1c(SCC(=O)N2CCCC2)nnc1c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C05 compound treatment 0.314 0.0791 4.25 4.2503 1.0 1987732 ChemDiv2_006737 Cc1ccc(Cl)cc1N2CCN(CC2)C(=O)C3CCCN(C3)S(=O)(=O)c4c[nH]cn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C06 compound treatment 0.274 0.0391 2.1 2.1008 1.0 1987733 ChemDiv2_006738 CN(C(=O)c1cc2c(=O)oc3ccc(C)cc3c2s1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C07 compound treatment 0.282 0.0471 2.53 2.5307 1.0 1987734 ChemDiv2_006739 COc1ccc(NC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C08 compound treatment 0.327 0.0921 4.95 4.9489 1.0 1987735 ChemDiv2_006740 COc1cccc(CC(=O)n2nc(N)c3cc4ccc(OC)cc4nc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C09 compound treatment 0.344 0.109 5.86 5.8625 1.0 1987736 ChemDiv2_006741 COc1ccc(OC)c(NC(=O)c2nnn(CCc3ccccc3)c2N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C10 compound treatment 0.29 0.0551 2.96 2.9606 1.0 1987737 ChemDiv2_006742 CCCNC(=O)c1ccc2C(O)N(CCC)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C11 compound treatment 0.297 0.0621 3.34 3.3368 1.0 1987738 ChemDiv2_006743 COc1ccc(NC(=O)C(CCS(=O)(=O)C)N2Cc3ccccc3C2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C12 compound treatment 0.25 0.0151 0.81 0.8111 1.0 1987739 ChemDiv2_006744 OC(=O)CSc1c2CCCCc2nc3cc(ccc13)C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C13 compound treatment 0.334 0.0991 5.33 5.3251 1.0 1987740 ChemDiv2_006745 Cc1ccccc1NC(=O)CCc2c(C)nc3cc(nn3c2C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C14 compound treatment 0.477 0.242 13.01 13.0096 1.0 1987741 ChemDiv2_006746 Clc1c2CCCCc2nc3cc(ccc13)C(=O)NCCCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C15 compound treatment 0.269 0.0341 1.83 1.8321 1.0 1987742 ChemDiv2_006747 Cc1nn2c(C)c(CCC(=O)NCCN3CCCC3)c(C)nc2c1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C16 compound treatment 0.369 0.134 7.21 7.2059 1.0 1987743 ChemDiv2_006748 CC(C)NCc1nc(no1)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C17 compound treatment 0.257 0.0221 1.19 1.1873 1.0 1987744 ChemDiv2_006749 Cc1nc2ncnn2c(C)c1CCC(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C18 compound treatment 0.265 0.0301 1.62 1.6172 1.0 1987745 ChemDiv2_006750 CCOC(=O)CSc1nc2c3ccccc3sc2c(=O)n1CCCC(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C19 compound treatment 0.298 0.0631 3.39 3.3905 1.0 1987746 ChemDiv2_006751 CC1CCCCC1NC(=O)C(Cc2ccccc2)NS(=O)(=O)c3ccc4n(C)c(=O)oc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C20 compound treatment 0.232 -0.00291 -0.16 -0.1562 -1.0 1987747 ChemDiv2_006752 CC1CCN(CC(O)c2ccc3cc[nH]c3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C21 compound treatment 0.434 0.199 10.7 10.6989 1.0 1987748 ChemDiv2_006753 Cc1ccc(cc1C)S(=O)(=O)c2cc3ccc(O)cc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C22 compound treatment 0.243 0.00809 0.43 0.4349 1.0 1987749 ChemDiv2_006754 COc1ccc(cc1)N2CCN(CC2)C(C(C)NC(=O)c3c(F)cccc3F)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C23 mock treatment 0.249 0.0141 0.76 0.7574 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 C24 mock treatment 0.241 0.00609 0.33 0.3275 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D01 compound treatment 0.237 0.00209 0.11 0.1125 1.0 1987750 ChemDiv2_006755 COc1ccc(cc1)c2nc(SCC(=O)Nc3cccc(C)c3)c4c(=O)n(C)c(=O)n(C)c4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D02 compound treatment 0.259 0.0241 1.29 1.2947 1.0 1987751 ChemDiv2_006756 O=c1c(c[nH]c2ccccc12)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D03 compound treatment 0.263 0.0281 1.51 1.5097 1.0 1987752 ChemDiv2_006757 OC1N(Cc2ccco2)C(=O)c3cc(ccc13)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D04 compound treatment 0.508 0.273 14.68 14.6755 1.0 1987753 ChemDiv2_006758 CC(C)C(=O)Nc1cccc(c1)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D05 compound treatment 0.253 0.0181 0.97 0.9723 1.0 1987754 ChemDiv2_006759 CN(C1CCCC1)C2CCN(CC2)c3cc(C)c4ccc(O)cc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D06 compound treatment 0.492 0.257 13.82 13.8157 1.0 1987755 ChemDiv2_006760 O=C(Nc1ccc(cc1)c2cn3cccnc3n2)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D07 compound treatment 0.248 0.0131 0.7 0.7036 1.0 1987756 ChemDiv2_006761 Cc1ccc2oc(=O)c3cnn(CC(=O)NCCCN4CCc5ccccc5C4)c3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D08 compound treatment 0.247 0.0121 0.65 0.6499 1.0 1987757 ChemDiv2_006762 COc1ccc(NC(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D09 compound treatment 0.247 0.0121 0.65 0.6499 1.0 1987758 ChemDiv2_006763 Cc1ccc2oc(=O)c3cnn(CC(=O)Nc4cc(no4)c5cccc(Cl)c5)c3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D10 compound treatment 0.341 0.106 5.7 5.7013 1.0 1987759 ChemDiv2_006764 COc1ccc(cc1)C2=NOC(C2)C(=O)N(C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D11 compound treatment 0.265 0.0301 1.62 1.6172 1.0 1987760 ChemDiv2_006765 CN(C(=O)c1cc(C)no1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D12 compound treatment 0.485 0.25 13.44 13.4395 1.0 1987761 ChemDiv2_006766 CN(Cc1ccccc1)C(=O)C2CC(=NO2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D13 compound treatment 0.316 0.0811 4.36 4.3578 1.0 1987762 ChemDiv2_006767 Cc1noc(C(=O)Nc2sc3CCCc3c2C#N)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D14 compound treatment 0.27 0.0351 1.89 1.8859 1.0 1987763 ChemDiv2_006768 COc1ccc(cc1OC)C2=NOC(C2)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D15 compound treatment 0.289 0.0541 2.91 2.9069 1.0 1987764 ChemDiv2_006769 Cc1ccccc1NC(=O)c2cc3c(C)nc4ccccc4c3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D16 compound treatment 0.275 0.0401 2.15 2.1546 1.0 1987765 ChemDiv2_006770 Fc1ccc(Cn2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D17 compound treatment 0.254 0.0191 1.03 1.0261 1.0 1987766 ChemDiv2_006771 CC1CC(C)CN(C1)c2cc(=O)n(Cc3ccc(F)cc3)c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D18 compound treatment 0.24 0.00509 0.27 0.2737 1.0 1987767 ChemDiv2_006772 COc1ccc(NC(=O)Cn2cnc3n(nnc3c2=O)c4cccc(Cl)c4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D19 compound treatment 0.23 -0.00491 -0.26 -0.2637 -1.0 1987768 ChemDiv2_006773 Clc1ccc(cc1)n2c(=O)cc(NCC3CCCO3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D20 compound treatment 0.249 0.0141 0.76 0.7574 1.0 1987769 ChemDiv2_006774 COc1ccc2cc3c(NC(=O)c4cnccn4)n[nH]c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D21 compound treatment 0.262 0.0271 1.46 1.456 1.0 1987770 ChemDiv2_006775 Cc1ccccc1n2c(=O)cc([nH]c2=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D22 compound treatment 0.359 0.124 6.67 6.6685 1.0 1987771 ChemDiv2_006776 CCC(C)NC(=O)c1cc2CSc3ccccc3-c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D23 mock treatment 0.232 -0.00291 -0.16 -0.1562 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 D24 mock treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E01 compound treatment 0.234 -9.06E-4 -0.05 -0.0487 -1.0 1987772 ChemDiv2_006777 Cc1nn2c(cc(C)nc2c1c3ccccc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E02 compound treatment 0.251 0.0161 0.86 0.8648 1.0 1987773 ChemDiv2_006778 COc1ccc(NC(=O)C(CC(C)C)NS(=O)(=O)c2ccc3nc(C)sc3c2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E03 compound treatment 0.279 0.0441 2.37 2.3695 1.0 1987774 ChemDiv2_006779 CCOC(=O)NCc1ccc2[nH]c(C)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E04 compound treatment 0.417 0.182 9.79 9.7853 1.0 1987775 ChemDiv2_006780 COCCn1c(SCC(=O)Nc2ccc3OCOc3c2)nnc1c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E05 compound treatment 0.249 0.0141 0.76 0.7574 1.0 1987776 ChemDiv2_006781 CC(C)C(NS(=O)(=O)c1cccc2nsnc12)C(=O)N3CCn4c3nc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E06 compound treatment 0.272 0.0371 1.99 1.9933 1.0 1987777 ChemDiv2_006782 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E07 compound treatment 0.286 0.0511 2.75 2.7457 1.0 1987778 ChemDiv2_006783 CC(NC(=O)C1CCC(CNS(=O)(=O)c2cccc3nsnc23)CC1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E08 compound treatment 0.262 0.0271 1.46 1.456 1.0 1987779 ChemDiv2_006784 COc1ccc2cc3c(N)nn(C(=O)Cc4ccccc4OC)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E09 compound treatment 0.293 0.0581 3.12 3.1218 1.0 1987780 ChemDiv2_006785 CC(NC(=O)C(N1Cc2ccccc2C1=O)c3ccccc3)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E10 compound treatment 0.271 0.0361 1.94 1.9396 1.0 1987781 ChemDiv2_006786 Cn1c(=O)n(C)c2ccc(cc2c1=O)S(=O)(=O)NC(Cc3ccccc3)C(=O)NC4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E11 compound treatment 0.45 0.215 11.56 11.5587 1.0 1987782 ChemDiv2_006787 COc1cc(OC)cc(c1)c2cc3nc(C)c(CCC(=O)NC(C)c4cccs4)c(C)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E12 compound treatment 0.294 0.0591 3.18 3.1756 1.0 1987783 ChemDiv2_006788 COc1cc(NC(=O)c2ccc3c(SCC(=O)O)c4CCCCc4nc3c2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E13 compound treatment 0.359 0.124 6.67 6.6685 1.0 1987784 ChemDiv2_006789 CCOC(=O)N1CCC(CC1)NC(=O)CCc2c(C)nc3cc(nn3c2C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E14 compound treatment 0.436 0.201 10.81 10.8064 1.0 1987785 ChemDiv2_006790 Clc1c2CCCCc2nc3cc(ccc13)C(=O)Nc4ccccc4C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E15 compound treatment 0.258 0.0231 1.24 1.241 1.0 1987786 ChemDiv2_006791 COc1ccc(cc1)N2Cc3cccc(C(=O)Nc4ccccc4)c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E16 compound treatment 0.321 0.0861 4.63 4.6265 1.0 1987787 ChemDiv2_006792 O=C(CSC1=NS(=O)(=O)c2ccccc12)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E17 compound treatment 0.295 0.0601 3.23 3.2293 1.0 1987788 ChemDiv2_006793 COc1ccc(CNC(=O)CCc2c(C)nc3nc(C)nn3c2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E18 compound treatment 0.327 0.0921 4.95 4.9489 1.0 1987789 ChemDiv2_006794 CSc1nc2c3ccccc3sc2c(=O)n1CCCC(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E19 compound treatment 0.274 0.0391 2.1 2.1008 1.0 1987790 ChemDiv2_006795 Cc1ccc(NC(=O)C(Cc2ccccc2)NS(=O)(=O)c3ccc4n(C)c(=O)oc4c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E20 compound treatment 0.28 0.0451 2.42 2.4232 1.0 1987791 ChemDiv2_006796 CCOC(=O)N1CCN(CC(O)c2ccc3cc[nH]c3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E21 compound treatment 0.297 0.0621 3.34 3.3368 1.0 1987792 ChemDiv2_006797 COc1ccc(cc1OC)S(=O)(=O)c2cc3cc(Br)ccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E22 compound treatment 0.312 0.0771 4.14 4.1429 1.0 1987793 ChemDiv2_006798 Cc1nc(SCC(=O)N2CCCC2)c3c(=O)n(C)c(=O)n(C)c3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E23 mock treatment 0.248 0.0131 0.7 0.7036 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 E24 mock treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F01 compound treatment 0.235 9.37E-5 0.01 0.005 1.0 1987794 ChemDiv2_006799 COc1ccc(cc1)c2nc(SCC(=O)NCc3ccccc3)c4c(=O)n(C)c(=O)n(C)c4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F02 compound treatment 0.305 0.0701 3.77 3.7667 1.0 1987795 ChemDiv2_006800 Cc1ccc(cc1)S(=O)(=O)c2c[nH]c3cc4OCOc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F03 compound treatment 0.5 0.265 14.25 14.2456 1.0 1987796 ChemDiv2_006801 COc1ccc(CCNC(=O)c2cc3ccccn3n2)c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F04 compound treatment 0.505 0.27 14.51 14.5143 1.0 1987797 ChemDiv2_006802 O=C(Nc1cccc(c1)c2cn3cccnc3n2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F05 compound treatment 0.31 0.0751 4.04 4.0354 1.0 1987798 ChemDiv2_006803 COc1ccc(Cn2c(CCC(=O)NC3CCCC3)nc4cccnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F06 compound treatment 0.526 0.291 15.64 15.6428 1.0 1987799 ChemDiv2_006804 O=C(CCC1CCCC1)Nc2ccc(cc2)c3cn4cccnc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F07 compound treatment 0.277 0.0421 2.26 2.262 1.0 1987800 ChemDiv2_006805 Cc1ccc2oc(=O)c3cnn(CC(=O)NCCN4CCN(CC4)c5ccccc5F)c3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F08 compound treatment 0.244 0.00909 0.49 0.4887 1.0 1987801 ChemDiv2_006806 CCN1CCN(CC1)C(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F09 compound treatment 0.257 0.0221 1.19 1.1873 1.0 1987802 ChemDiv2_006807 CCOc1ccccc1c2cc(NC(=O)Cn3ncc4c(=O)oc5ccc(C)cc5c34)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F10 compound treatment 0.386 0.151 8.12 8.1195 1.0 1987803 ChemDiv2_006808 CCN(CC)C(=O)C1CC(=NO1)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F11 compound treatment 0.25 0.0151 0.81 0.8111 1.0 1987804 ChemDiv2_006809 Cc1cc(on1)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F12 compound treatment 0.43 0.195 10.48 10.4839 1.0 1987805 ChemDiv2_006810 CC1CCCCN1C(=O)C2CC(=NO2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F13 compound treatment 0.249 0.0141 0.76 0.7574 1.0 1987806 ChemDiv2_006811 COc1ccc(cc1)N(CC(=O)NCc2cccs2)S(=O)(=O)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F14 compound treatment 0.424 0.189 10.16 10.1615 1.0 1135408 ChemDiv2_006812 O=c1n(nc2oc3ccccc3cc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F15 compound treatment 0.493 0.258 13.87 13.8694 1.0 1987807 ChemDiv2_006813 Cc1nc2ccccc2c3oc(cc13)C(=O)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F16 compound treatment 0.407 0.172 9.25 9.248 1.0 1987808 ChemDiv2_006814 Fc1ccc(Cn2nnc3c(=O)n(CC(=O)OCc4ccccc4)cnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F17 compound treatment 0.248 0.0131 0.7 0.7036 1.0 1987809 ChemDiv2_006815 Fc1ccc(Cn2c(=O)cc(NCc3cccs3)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F18 compound treatment 0.313 0.0781 4.2 4.1966 1.0 1987810 ChemDiv2_006816 CCOC(=O)C(CC)n1cnc2n(nnc2c1=O)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F19 compound treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1987811 ChemDiv2_006817 Clc1ccc(cc1)n2c(=O)cc(NCc3ccco3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F20 compound treatment 0.231 -0.00391 -0.21 -0.2099 -1.0 1987812 ChemDiv2_006818 COc1cc2C(C3CCCCN3C(=O)c2cc1OC)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F21 compound treatment 0.228 -0.00691 -0.37 -0.3711 -1.0 1987813 ChemDiv2_006819 Cc1ccccc1n2c(=O)cc(NCC3CCCO3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F22 compound treatment 0.222 -0.0129 -0.69 -0.6936 -1.0 1987814 ChemDiv2_006820 Cc1ncoc1C(=O)NC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F23 mock treatment 0.232 -0.00291 -0.16 -0.1562 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 F24 mock treatment 0.226 -0.00891 -0.48 -0.4786 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G01 compound treatment 0.25 0.0151 0.81 0.8111 1.0 1987815 ChemDiv2_006821 COc1ccc(cc1OC)c2c(C)nn3c(NCCN4CCCC4)cc(C)nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G02 compound treatment 0.289 0.0541 2.91 2.9069 1.0 1987816 ChemDiv2_006822 COc1ccc(CNC(=O)C(CC(C)C)NS(=O)(=O)c2ccc3nc(C)sc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G03 compound treatment 0.237 0.00209 0.11 0.1125 1.0 1987817 ChemDiv2_006823 Cc1cc2cc(CNC(=O)CCC(=O)O)ccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G04 compound treatment 0.463 0.228 12.26 12.2573 1.0 1987818 ChemDiv2_006824 COc1ccc(OC)c(c1)n2c(SCC(=O)N3CCOCC3)nnc2c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G05 compound treatment 0.248 0.0131 0.7 0.7036 1.0 1987819 ChemDiv2_006825 CN(Cc1ccccc1)C(=O)C2CCCN2S(=O)(=O)c3cccc4nsnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G06 compound treatment 0.471 0.236 12.69 12.6872 1.0 1987820 ChemDiv2_006826 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)NCCN4CCc5ccccc5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G07 compound treatment 0.349 0.114 6.13 6.1312 1.0 1987821 ChemDiv2_006827 COc1ccc(cc1)N(C)C(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G08 compound treatment 0.316 0.0811 4.36 4.3578 1.0 1987822 ChemDiv2_006828 COc1ccc2cc3c(N)nn(C(=O)CCS(=O)(=O)c4ccccc4)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G09 compound treatment 0.438 0.203 10.91 10.9138 1.0 1987823 ChemDiv2_006829 O=C(NCc1cccs1)C(CSCc2ccccc2)N3Cc4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G10 compound treatment 0.481 0.246 13.22 13.2246 1.0 1987824 ChemDiv2_006830 Cn1c(=O)n(C)c2ccc(cc2c1=O)S(=O)(=O)NC(C(=O)N3CCCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G11 compound treatment 0.443 0.208 11.18 11.1825 1.0 1987825 ChemDiv2_006831 Cc1nc2cc(nn2c(C)c1CCC(=O)NC3CCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G12 compound treatment 0.419 0.184 9.89 9.8928 1.0 1987826 ChemDiv2_006832 COc1cc(OC)c(NC(=O)c2ccc3c(SCC(=O)O)c4CCCCc4nc3c2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G13 compound treatment 0.483 0.248 13.33 13.332 1.0 1987827 ChemDiv2_006833 CC(NC(=O)CCc1c(C)nc2cc(nn2c1C)c3ccccc3)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G14 compound treatment 0.52 0.285 15.32 15.3203 1.0 1987828 ChemDiv2_006834 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(Cl)c4CCCCc4nc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G15 compound treatment 0.552 0.317 17.04 17.04 1.0 1987829 ChemDiv2_006835 COc1ccc(NC(=O)CCc2c(C)nc3cc(nn3c2C)c4ccc(OC)cc4OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G16 compound treatment 0.285 0.0501 2.69 2.6919 1.0 1987830 ChemDiv2_006836 COc1ccc(CCNC(=O)CSC2=NS(=O)(=O)c3ccccc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G17 compound treatment 0.288 0.0531 2.85 2.8531 1.0 1987831 ChemDiv2_006837 CCOC(=O)N1CCC(CC1)NC(=O)CCc2c(C)nc3ncnn3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G18 compound treatment 0.292 0.0571 3.07 3.0681 1.0 1987832 ChemDiv2_006838 O=S(=O)(N1CCn2c(C1)nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G19 compound treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1987833 ChemDiv2_006839 COc1ccc(NC(=O)C(NS(=O)(=O)c2ccc3n(C)c(=O)oc3c2)C(C)C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G20 compound treatment 0.262 0.0271 1.46 1.456 1.0 1987834 ChemDiv2_006840 COc1ccccc1N2CCN(CC(O)c3ccc4cc[nH]c4c3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G21 compound treatment 0.353 0.118 6.35 6.3461 1.0 1987835 ChemDiv2_006841 CCN(CC)c1ccc2cc(c(=O)oc2c1)S(=O)(=O)c3ccc(F)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G22 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1987836 ChemDiv2_006842 Cc1nc(SCC(=O)N2CCCc3ccccc23)c4c(=O)n(C)c(=O)n(C)c4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G23 mock treatment 0.242 0.00709 0.38 0.3812 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 G24 mock treatment 0.245 0.0101 0.54 0.5424 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H01 compound treatment 0.257 0.0221 1.19 1.1873 1.0 1987837 ChemDiv2_006843 COC(=O)c1ccc(CSc2nc(nc3n(C)c(=O)n(C)c(=O)c23)c4ccc(OC)cc4)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H02 compound treatment 0.297 0.0621 3.34 3.3368 1.0 1987838 ChemDiv2_006844 CCOC(=O)c1ccc(N=c2sc(cc(=O)n2CCCN3CCOCC3)C(=O)OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H03 compound treatment 0.266 0.0311 1.67 1.6709 1.0 1987839 ChemDiv2_006845 Cc1cc(nc2cc(O)ccc12)N3CCN(CC3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H04 compound treatment 0.556 0.321 17.25 17.2549 1.0 1987840 ChemDiv2_006846 Cc1ccc(cc1)C(=O)Nc2cccc(c2)c3cn4cccnc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H05 compound treatment 0.286 0.0511 2.75 2.7457 1.0 1987841 ChemDiv2_006847 O=C(CCc1nc2cccnc2n1Cc3ccccc3)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H06 compound treatment 0.572 0.337 18.11 18.1147 1.0 1987842 ChemDiv2_006848 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)c3cn4cccnc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H07 compound treatment 0.266 0.0311 1.67 1.6709 1.0 1987843 ChemDiv2_006849 Cc1ccc2oc(=O)c3cnn(CC(=O)Nc4ccccc4C)c3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H08 compound treatment 0.516 0.281 15.11 15.1054 1.0 1987844 ChemDiv2_006850 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCC(CC3)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H09 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1987845 ChemDiv2_006851 Cc1ccc2cc3c(N)nn(C(=O)c4ccncc4)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H10 compound treatment 0.419 0.184 9.89 9.8928 1.0 1987846 ChemDiv2_006852 COc1ccc(cc1)C2=NOC(C2)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H11 compound treatment 0.346 0.111 5.97 5.9699 1.0 1987847 ChemDiv2_006853 Cc1cc(on1)C(=O)N2CCC(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H12 compound treatment 0.435 0.2 10.75 10.7526 1.0 1987848 ChemDiv2_006854 Fc1ccc(cc1)C2=NOC(C2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H13 compound treatment 0.447 0.212 11.4 11.3975 1.0 1987849 ChemDiv2_006855 O=C(N1CCCC1)c2cc3ccccn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H14 compound treatment 0.277 0.0421 2.26 2.262 1.0 1987850 ChemDiv2_006856 COc1cccc2cc3c(=O)n(nc3oc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H15 compound treatment 0.384 0.149 8.01 8.012 1.0 1987851 ChemDiv2_006857 CC1CCC(CC1)NC(=O)c2cc3c(C)nc4ccccc4c3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H16 compound treatment 0.355 0.12 6.45 6.4536 1.0 1987852 ChemDiv2_006858 Fc1ccc(Cn2nnc3c(=O)n(CC(=O)c4ccc(Cl)cc4)cnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H17 compound treatment 0.352 0.117 6.29 6.2924 1.0 1987853 ChemDiv2_006859 NS(=O)(=O)c1ccc(CCNc2cc(=O)n(Cc3ccc(F)cc3)c(=O)[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H18 compound treatment 0.384 0.149 8.01 8.012 1.0 1987854 ChemDiv2_006860 COc1cccc(c1)n2nnc3c(=O)n(C/C=C/c4ccccc4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H19 compound treatment 0.261 0.0261 1.4 1.4022 1.0 1987855 ChemDiv2_006861 Clc1ccc(cc1)n2c(=O)cc(Nc3ccc4OCCOc4c3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H20 compound treatment 0.31 0.0751 4.04 4.0354 1.0 1987856 ChemDiv2_006862 Fc1ccc(NC(=O)c2ccc3c(Cl)c4CCCc4nc3c2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H21 compound treatment 0.247 0.0121 0.65 0.6499 1.0 1987857 ChemDiv2_006863 Cc1ccccc1n2c(=O)cc(NCCCn3ccnc3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H22 compound treatment 0.244 0.00909 0.49 0.4887 1.0 1987858 ChemDiv2_006864 Cc1ncoc1C(=O)Nc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H23 mock treatment 0.234 -9.06E-4 -0.05 -0.0487 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 H24 mock treatment 0.248 0.0131 0.7 0.7036 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I01 compound treatment 0.231 -0.00391 -0.21 -0.2099 -1.0 1987859 ChemDiv2_006865 COc1ccc(cc1OC)c2c(C)nn3c(cc(C)nc23)N4CCN(CC4)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I02 compound treatment 0.257 0.0221 1.19 1.1873 1.0 1987860 ChemDiv2_006866 COc1ccccc1CNC(=O)C(CC(C)C)NS(=O)(=O)c2ccc3nc(C)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I03 compound treatment 0.307 0.0721 3.87 3.8742 1.0 1987861 ChemDiv2_006867 CCOC(=O)NCc1ccc2n(C)c(C)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I04 compound treatment 0.312 0.0771 4.14 4.1429 1.0 1987862 ChemDiv2_006868 COc1ccc(OC)c(c1)n2c(SCC(=O)NCC3CCCO3)nnc2c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I05 compound treatment 0.25 0.0151 0.81 0.8111 1.0 1987863 ChemDiv2_006869 CCN(C(=O)C1CCCN1S(=O)(=O)c2cccc3nsnc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I06 compound treatment 0.318 0.0831 4.47 4.4653 1.0 1987864 ChemDiv2_006870 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)NCCN4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I07 compound treatment 0.551 0.316 16.99 16.9862 1.0 1987865 ChemDiv2_006871 CN(CC(=O)N1CCn2c1nc3ccccc23)S(=O)(=O)c4ccc5NC(=O)CCc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I08 compound treatment 0.493 0.258 13.87 13.8694 1.0 1987866 ChemDiv2_006872 COc1ccc(CC(=O)n2nc(N)c3cc4ccc(OC)cc4nc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I09 compound treatment 0.552 0.317 17.04 17.04 1.0 1987867 ChemDiv2_006873 COc1ccc(NC(=O)C(CSCc2ccccc2)N3Cc4ccccc4C3=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I10 compound treatment 0.279 0.0441 2.37 2.3695 1.0 1987868 ChemDiv2_006874 CN(CC(=O)NC1CCCCCC1)S(=O)(=O)c2ccc3n(C)c(=O)n(C)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I11 compound treatment 0.546 0.311 16.72 16.7175 1.0 1987869 ChemDiv2_006875 Cc1nc2cc(nn2c(C)c1CCC(=O)Nc3ccc4OCOc4c3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I12 compound treatment 0.259 0.0241 1.29 1.2947 1.0 1987870 ChemDiv2_006876 OC(=O)CSc1c2CCCCc2nc3cc(ccc13)C(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I13 compound treatment 0.5 0.265 14.25 14.2456 1.0 1987871 ChemDiv2_006877 Cc1nc2cc(nn2c(C)c1CCC(=O)N3CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I14 compound treatment 0.371 0.136 7.31 7.3134 1.0 1987872 ChemDiv2_006878 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)C(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I15 compound treatment 0.264 0.0291 1.56 1.5634 1.0 1987873 ChemDiv2_006879 COc1ccc(c2cc3nc(C)c(CCC(=O)N4CCc5ccccc45)c(C)n3n2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I16 compound treatment 0.404 0.169 9.09 9.0867 1.0 1987874 ChemDiv2_006880 CCOC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N(C)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I17 compound treatment 0.275 0.0401 2.15 2.1546 1.0 1987875 ChemDiv2_006881 CCOC(=O)C1CCCCN1C(=O)CCc2c(C)nc3ncnn3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I18 compound treatment 0.261 0.0261 1.4 1.4022 1.0 1987876 ChemDiv2_006882 CCS(=O)(=O)N1CCn2c(C1)nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I19 compound treatment 0.375 0.14 7.53 7.5283 1.0 1987877 ChemDiv2_006883 CN(Cc1ccccc1)S(=O)(=O)c2ccc3N(CCc3c2)C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I20 compound treatment 0.236 0.00109 0.06 0.0588 1.0 1987878 ChemDiv2_006884 CN(CC(O)c1ccc2cc[nH]c2c1)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I21 compound treatment 0.422 0.187 10.05 10.054 1.0 1987879 ChemDiv2_006885 O=C(NC1CCCC1)c2cc3CSCc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I22 compound treatment 0.237 0.00209 0.11 0.1125 1.0 1987880 ChemDiv2_006886 Cc1nc(SCC(=O)N)c2c(=O)n(C)c(=O)n(C)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I23 mock treatment 0.244 0.00909 0.49 0.4887 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 I24 mock treatment 0.238 0.00309 0.17 0.1663 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J01 compound treatment 0.243 0.00809 0.43 0.4349 1.0 1987881 ChemDiv2_006887 COC(=O)C(C)Sc1nc(nc2n(C)c(=O)n(C)c(=O)c12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J02 compound treatment 0.515 0.28 15.05 15.0517 1.0 1987882 ChemDiv2_006888 CCOc1ccc(cc1)c2cc(CCCC(=O)Nc3cc(Cl)ccc3O)no2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J03 compound treatment 0.386 0.151 8.12 8.1195 1.0 1987883 ChemDiv2_006889 Cc1cc(nc2cc(O)ccc12)N3CCN(CC3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J04 compound treatment 0.587 0.352 18.92 18.9208 1.0 1987884 ChemDiv2_006890 COc1cccc(C(=O)Nc2cccc(c2)c3cn4cccnc4n3)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J05 compound treatment 0.441 0.206 11.08 11.075 1.0 1987885 ChemDiv2_006891 O=C(CCc1nc2cccnc2n1Cc3ccccc3)NCCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J06 compound treatment 0.545 0.31 16.66 16.6638 1.0 1987886 ChemDiv2_006892 O=C(COc1ccccc1)Nc2ccc(cc2)c3cn4cccnc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J07 compound treatment 0.247 0.0121 0.65 0.6499 1.0 1987887 ChemDiv2_006893 CC1CCCC(C)N1C(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J08 compound treatment 0.493 0.258 13.87 13.8694 1.0 1987888 ChemDiv2_006894 COc1ccc(cc1)C2=NOC(C2)C(=O)Nc3ccc(C#N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J09 compound treatment 0.331 0.0961 5.16 5.1639 1.0 1987889 ChemDiv2_006895 CN(C)CCNc1cc(N2CCOCC2)c3noc4-c5ccccc5C(=O)c1c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J10 compound treatment 0.308 0.0731 3.93 3.9279 1.0 1987890 ChemDiv2_006896 CCc1ccccc1NC(=O)C2CC(=NO2)c3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J11 compound treatment 0.292 0.0571 3.07 3.0681 1.0 1987891 ChemDiv2_006897 Cc1cc(on1)C(=O)Nc2c(C)nn(Cc3ccccc3)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J12 compound treatment 0.432 0.197 10.59 10.5914 1.0 1987892 ChemDiv2_006898 Fc1ccc(cc1)C2=NOC(C2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J13 compound treatment 0.503 0.268 14.41 14.4068 1.0 1987893 ChemDiv2_006899 COc1ccc(OC)c(NC(=O)c2cc3ccccn3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J14 compound treatment 0.266 0.0311 1.67 1.6709 1.0 1987894 ChemDiv2_006900 CCOc1cccc2cc3c(=O)n(nc3oc12)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J15 compound treatment 0.264 0.0291 1.56 1.5634 1.0 1987895 ChemDiv2_006901 Cc1nc2ccccc2c3oc(cc13)C(=O)NCCN4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J16 compound treatment 0.386 0.151 8.12 8.1195 1.0 1987896 ChemDiv2_006902 COc1ccc(NC(=O)Cn2cnc3n(Cc4ccccc4F)nnc3c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J17 compound treatment 0.249 0.0141 0.76 0.7574 1.0 1987897 ChemDiv2_006903 Fc1ccc(Cn2c(=O)cc([nH]c2=O)N3CCc4ccccc34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J18 compound treatment 0.522 0.287 15.43 15.4278 1.0 1987898 ChemDiv2_006904 COc1cccc(c1)n2nnc3c(=O)n(Cc4ccc(C)cc4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J19 compound treatment 0.236 0.00109 0.06 0.0588 1.0 1987899 ChemDiv2_006905 COc1ccc(cc1)n2c(=O)cc([nH]c2=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J20 compound treatment 0.397 0.162 8.71 8.7106 1.0 1987900 ChemDiv2_006906 NS(=O)(=O)c1ccc(Nc2c3CCCc3nc4ccc(Cl)cc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J21 compound treatment 0.272 0.0371 1.99 1.9933 1.0 1987901 ChemDiv2_006907 Cc1ccccc1n2c(=O)cc(NCc3ccc4OCOc4c3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J22 compound treatment 0.276 0.0411 2.21 2.2083 1.0 1987902 ChemDiv2_006908 Fc1ccccc1NC(=O)CSc2nnc(Cn3c(=O)sc4ccccc34)n2c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J23 mock treatment 0.243 0.00809 0.43 0.4349 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 J24 mock treatment 0.238 0.00309 0.17 0.1663 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K01 compound treatment 0.257 0.0221 1.19 1.1873 1.0 1987903 ChemDiv2_006909 Cc1nn2c(cc(C)nc2c1c3ccc(Cl)cc3)N4CCC(CC4)C(=O)NC(=O)C5CCNCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K02 compound treatment 0.333 0.0981 5.27 5.2714 1.0 1987904 ChemDiv2_006910 Oc1ccc2cc(C(=O)c3ccc4OCOc4c3)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K03 compound treatment 0.449 0.214 11.5 11.505 1.0 1987905 ChemDiv2_006911 COc1ccc(cc1)N(CC(=O)N2CCc3ccccc23)S(=O)(=O)c4c(C)[nH]c(=O)[nH]c4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K04 compound treatment 0.427 0.192 10.32 10.3227 1.0 1987906 ChemDiv2_006912 CCOC(=O)CSc1nnc(c2c[nH]c3ccccc23)n1c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K05 compound treatment 0.265 0.0301 1.62 1.6172 1.0 1987907 ChemDiv2_006913 CN(C(=O)C1CCCN1S(=O)(=O)c2cccc3nsnc23)c4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K06 compound treatment 0.371 0.136 7.31 7.3134 1.0 1987908 ChemDiv2_006914 CN1CCN(CCNC(=O)c2cc3c(=O)oc4ccc(C)cc4c3s2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K07 compound treatment 0.38 0.145 7.8 7.797 1.0 1987909 ChemDiv2_006915 CN(CC(=O)Nc1nccs1)S(=O)(=O)c2ccc3NC(=O)CCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K08 compound treatment 0.292 0.0571 3.07 3.0681 1.0 1987910 ChemDiv2_006916 COc1ccc2cc3c(N)nn(C(=O)CSc4ccncc4)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K09 compound treatment 0.478 0.243 13.06 13.0633 1.0 1987911 ChemDiv2_006917 CSCCC(N1Cc2ccccc2C1=O)C(=O)Nc3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K10 compound treatment 0.259 0.0241 1.29 1.2947 1.0 1987912 ChemDiv2_006918 CN(CC(=O)N1CCc2ccccc12)S(=O)(=O)c3ccc4n(C)c(=O)n(C)c(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K11 compound treatment 0.508 0.273 14.68 14.6755 1.0 1987913 ChemDiv2_006919 Cc1nc2cc(nn2c(C)c1CCC(=O)NCCCN3CCCC3=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K12 compound treatment 0.248 0.0131 0.7 0.7036 1.0 1987914 ChemDiv2_006920 OC(=O)CSc1c2CCCCc2nc3cc(ccc13)C(=O)N4CCCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K13 compound treatment 0.501 0.266 14.3 14.2993 1.0 1987915 ChemDiv2_006921 Cc1nc2cc(nn2c(C)c1CCC(=O)NO)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K14 compound treatment 0.34 0.105 5.65 5.6475 1.0 1987916 ChemDiv2_006922 CC(C)N(Cc1nc(no1)c2ccccc2)C(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K15 compound treatment 0.275 0.0401 2.15 2.1546 1.0 1987917 ChemDiv2_006923 CCOC(=O)C1CCCCN1C(=O)CCc2c(C)nc3cc(nn3c2C)c4ccc(OC)cc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K16 compound treatment 0.29 0.0551 2.96 2.9606 1.0 1987918 ChemDiv2_006924 CCOC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K17 compound treatment 0.264 0.0291 1.56 1.5634 1.0 1987919 ChemDiv2_006925 Cc1nc2ncnn2c(C)c1CCC(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K18 compound treatment 0.24 0.00509 0.27 0.2737 1.0 1987920 ChemDiv2_006926 OC(CN1CCCCC1)c2ccc3cc[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K19 compound treatment 0.402 0.167 8.98 8.9793 1.0 1987921 ChemDiv2_006927 OC(=O)CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)N(CCc3ccccc3)Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K20 compound treatment 0.27 0.0351 1.89 1.8859 1.0 1987922 ChemDiv2_006928 OC(CN1CCN(CC1)c2ccccc2)c3ccc4NCCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K21 compound treatment 0.375 0.14 7.53 7.5283 1.0 1987923 ChemDiv2_006929 O=C(NC(=O)c1cc2CSCc2s1)C3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K22 compound treatment 0.242 0.00709 0.38 0.3812 1.0 1987924 ChemDiv2_006930 CCSc1nc(nc2n(C)c(=O)n(C)c(=O)c12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K23 mock treatment 0.23 -0.00491 -0.26 -0.2637 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 K24 mock treatment 0.239 0.00409 0.22 0.22 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L01 compound treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1987925 ChemDiv2_006931 Cn1c(=O)n(C)c2nc(nc(SCc3cccc(F)c3)c2c1=O)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L02 compound treatment 0.544 0.309 16.61 16.6101 1.0 1987926 ChemDiv2_006932 CCOc1ccc(cc1)c2cc(CCCC(=O)Nc3ccc(F)cc3F)no2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L03 compound treatment 0.297 0.0621 3.34 3.3368 1.0 1987927 ChemDiv2_006933 Cc1cc(nc2cc(O)ccc12)N3CCC(CC3)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L04 compound treatment 0.496 0.261 14.03 14.0306 1.0 1987928 ChemDiv2_006934 COc1ccc(cc1NC(=O)C)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L05 compound treatment 0.278 0.0431 2.32 2.3158 1.0 1987929 ChemDiv2_006935 CCOC(=O)N1CCC(CC1)c2nc(C)sc2C(=O)NCc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L06 compound treatment 0.413 0.178 9.57 9.5704 1.0 1987930 ChemDiv2_006936 CCCC(CCC)C(=O)Nc1cccc(c1)c2nc3ncccn3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L07 compound treatment 0.252 0.0171 0.92 0.9186 1.0 1987931 ChemDiv2_006937 CCN(CCN(C)C)C(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L08 compound treatment 0.403 0.168 9.03 9.033 1.0 1987932 ChemDiv2_006938 COc1ccc(cc1)C2=NOC(C2)C(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L09 compound treatment 0.243 0.00809 0.43 0.4349 1.0 1987933 ChemDiv2_006939 Cc1cc(on1)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L10 compound treatment 0.516 0.281 15.11 15.1054 1.0 1987934 ChemDiv2_006940 COc1cccc(c1)C2=NOC(C2)C(=O)Nc3cc(C)on3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L11 compound treatment 0.246 0.0111 0.6 0.5962 1.0 1987935 ChemDiv2_006941 COC(=O)c1ccccc1NC(=O)c2onc(C)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L12 compound treatment 0.455 0.22 11.83 11.8274 1.0 1987936 ChemDiv2_006942 CN(C1CCCCC1)C(=O)C2CC(=NO2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L13 compound treatment 0.34 0.105 5.65 5.6475 1.0 1987937 ChemDiv2_006943 COc1ccc(cc1)N2CCN(CC2)C(=O)c3cc4ccccn4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L14 compound treatment 0.372 0.137 7.37 7.3671 1.0 1987938 ChemDiv2_006944 CCOC(=O)N1CCN(CC1)C(=O)Cn2cnc3n(Cc4ccc(C)cc4)nnc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L15 compound treatment 0.304 0.0691 3.71 3.713 1.0 1987939 ChemDiv2_006945 O=C1CC(CN1Cc2ccccc2)c3nc4ccccc4n3CCc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L16 compound treatment 0.35 0.115 6.18 6.1849 1.0 1987940 ChemDiv2_006946 Fc1ccccc1Cn2nnc3c(=O)n(CC(=O)NCc4ccc5OCOc5c4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L17 compound treatment 0.441 0.206 11.08 11.075 1.0 1987941 ChemDiv2_006947 Fc1ccc(Cn2c(=O)cc(Nc3ccc4OCOc4c3)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L18 compound treatment 0.455 0.22 11.83 11.8274 1.0 1987942 ChemDiv2_006948 COc1cccc(c1)n2nnc3c(=O)n(Cc4ccccc4F)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L19 compound treatment 0.229 -0.00591 -0.32 -0.3174 -1.0 1987943 ChemDiv2_006949 COC(=O)C1CCN(CC1)c2cc(=O)n(c3ccc(OC)cc3)c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L20 compound treatment 0.409 0.174 9.36 9.3554 1.0 1987944 ChemDiv2_006950 CCN1CCN(CCCNC(=O)c2cc3c(=O)[nH]c4ccc(C)cc4c3s2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L21 compound treatment 0.225 -0.00991 -0.53 -0.5323 -1.0 1987945 ChemDiv2_006951 Cc1ccc(cc1)n2c(=O)cc([nH]c2=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L22 compound treatment 0.34 0.105 5.65 5.6475 1.0 1987946 ChemDiv2_006952 O=c1sc2ccccc2n1Cc3nnc(SCc4ccccn4)n3c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L23 mock treatment 0.227 -0.00791 -0.42 -0.4249 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 L24 mock treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M01 compound treatment 0.229 -0.00591 -0.32 -0.3174 -1.0 1987947 ChemDiv2_006953 Cc1nn2c(cc(C)nc2c1c3ccc(Cl)cc3)N4CCC(CC4)C(=O)NCCN5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M02 compound treatment 0.272 0.0371 1.99 1.9933 1.0 1987948 ChemDiv2_006954 O=C(C1CCN(CC1)c2ccc(nn2)N3CCOCC3)N4CCN(CC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M03 compound treatment 0.299 0.0641 3.44 3.4443 1.0 1987949 ChemDiv2_006955 Cc1cc(C)cc(c1)N(CC(=O)NC2CCCc3ccccc23)S(=O)(=O)c4c(C)[nH]c(=O)[nH]c4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M04 compound treatment 0.351 0.116 6.24 6.2386 1.0 1987950 ChemDiv2_006956 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M05 compound treatment 0.253 0.0181 0.97 0.9723 1.0 1987951 ChemDiv2_006957 O=C(NCc1ccccc1)C2CCCN2S(=O)(=O)c3cccc4nsnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M06 compound treatment 0.366 0.131 7.04 7.0447 1.0 1987952 ChemDiv2_006958 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)N(CC4CCCO4)Cc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M07 compound treatment 0.381 0.146 7.85 7.8508 1.0 1987953 ChemDiv2_006959 CN(CC(=O)N1CCN(CC1)c2ccccc2)S(=O)(=O)c3ccc4NC(=O)CCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M08 compound treatment 0.464 0.229 12.31 12.311 1.0 1987954 ChemDiv2_006960 COc1ccc2cc3c(N)nn(C(=O)Cc4c[nH]c5ccccc45)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M09 compound treatment 0.534 0.299 16.07 16.0727 1.0 1987955 ChemDiv2_006961 CCOC(=O)c1ccc(CNC(=O)C(Cc2ccccc2)N3Cc4ccccc4C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M10 compound treatment 0.277 0.0421 2.26 2.262 1.0 1987956 ChemDiv2_006962 CN(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c3ccc4n(C)c(=O)n(C)c(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M11 compound treatment 0.463 0.228 12.26 12.2573 1.0 1987957 ChemDiv2_006963 Cc1nc2cc(nn2c(C)c1CCC(=O)NCCCc3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M12 compound treatment 0.306 0.0711 3.82 3.8204 1.0 1987958 ChemDiv2_006964 Cc1cc(NC(=O)c2ccc3c(Cl)c4CCCCc4nc3c2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M13 compound treatment 0.477 0.242 13.01 13.0096 1.0 1987959 ChemDiv2_006965 COc1cc(NC(=O)CCc2c(C)nc3cc(nn3c2C)c4cccc(F)c4)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M14 compound treatment 0.446 0.211 11.34 11.3437 1.0 1987960 ChemDiv2_006966 CC(C)N(Cc1nc(no1)c2ccccc2)C(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M15 compound treatment 0.265 0.0301 1.62 1.6172 1.0 1987961 ChemDiv2_006967 Cc1nc2ncnn2c(C)c1CCC(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M16 compound treatment 0.263 0.0281 1.51 1.5097 1.0 1987962 ChemDiv2_006968 CCOC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N(CC)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M17 compound treatment 0.387 0.152 8.17 8.1732 1.0 1987963 ChemDiv2_006969 CC(C)CC(NS(=O)(=O)c1ccc2n(C)c(=O)oc2c1)C(=O)Nc3nc(C)cs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M18 compound treatment 0.278 0.0431 2.32 2.3158 1.0 1987964 ChemDiv2_006970 OC1CCN(CC1)C(=O)c2oc(=O)c3ccccc3c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M19 compound treatment 0.263 0.0281 1.51 1.5097 1.0 1987965 ChemDiv2_006971 OC(=O)CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M20 compound treatment 0.291 0.0561 3.01 3.0144 1.0 1987966 ChemDiv2_006972 CC(=O)N1CCc2cc(ccc12)C(O)CN3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M21 compound treatment 0.236 0.00109 0.06 0.0588 1.0 1987967 ChemDiv2_006973 Cc1ccc(C(=O)c2[nH]c(=O)c3ccccc3c2O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M22 compound treatment 0.247 0.0121 0.65 0.6499 1.0 1987968 ChemDiv2_006974 COc1ccc(cc1)c2nc(SC3CCCC3)c4c(=O)n(C)c(=O)n(C)c4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M23 mock treatment 0.24 0.00509 0.27 0.2737 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 M24 mock treatment 0.243 0.00809 0.43 0.4349 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N01 compound treatment 0.233 -0.00191 -0.1 -0.1024 -1.0 1987969 ChemDiv2_006975 Cc1cc(NC(=O)CSc2nc(nc3n(C)c(=O)n(C)c(=O)c23)c4ccco4)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N02 compound treatment 0.546 0.311 16.72 16.7175 1.0 1987970 ChemDiv2_006976 CCOc1ccc(cc1)c2cc(CCCC(=O)Nc3cc(OC)ccc3OC)no2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N03 compound treatment 0.339 0.104 5.59 5.5938 1.0 1987971 ChemDiv2_006977 Nc1cc(nn1S(=O)(=O)c2ccc(Cl)cc2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N04 compound treatment 0.471 0.236 12.69 12.6872 1.0 1987972 ChemDiv2_006978 CC(=O)Nc1ccc(cc1)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N05 compound treatment 0.261 0.0261 1.4 1.4022 1.0 1987973 ChemDiv2_006979 Cc1ccc(cc1Cl)n2ncc(C(=O)N3CCOCC3)c2C4CCN(CC4)C(=O)OC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N06 compound treatment 0.515 0.28 15.05 15.0517 1.0 1987974 ChemDiv2_006980 Cc1c(nc2ncccn12)c3cccc(NC(=O)CCC4CCCC4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N07 compound treatment 0.251 0.0161 0.86 0.8648 1.0 1987975 ChemDiv2_006981 Cc1ccc(CCNC(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N08 compound treatment 0.265 0.0301 1.62 1.6172 1.0 1987976 ChemDiv2_006982 COc1ccc(cc1)C2=NOC(C2)C(=O)N3C(C)CCCC3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N09 compound treatment 0.286 0.0511 2.75 2.7457 1.0 1987977 ChemDiv2_006983 Cc1cc(on1)C(=O)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N10 compound treatment 0.369 0.134 7.21 7.2059 1.0 1987978 ChemDiv2_006984 COc1cccc(c1)C2=NOC(C2)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N11 compound treatment 0.272 0.0371 1.99 1.9933 1.0 1987979 ChemDiv2_006985 Cc1noc(C(=O)NC2CCCCC2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N12 compound treatment 0.314 0.0791 4.25 4.2503 1.0 1987980 ChemDiv2_006986 COCC(C)NC(=O)C1CC(=NO1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N13 compound treatment 0.351 0.116 6.24 6.2386 1.0 1987981 ChemDiv2_006987 O=C(NCc1ccccc1)c2cc3ccccn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N14 compound treatment 0.345 0.11 5.92 5.9162 1.0 1987982 ChemDiv2_006988 Cc1ccc(Cn2nnc3c(=O)n(CC(=O)NCc4ccccc4Cl)cnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N15 compound treatment 0.274 0.0391 2.1 2.1008 1.0 1987983 ChemDiv2_006989 COc1ccc(OC)c(c1)N2CC(CC2=O)c3nc4ccccc4n3Cc5ccccc5F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N16 compound treatment 0.466 0.231 12.42 12.4185 1.0 1987984 ChemDiv2_006990 Cc1ccc(C)c(Cn2cnc3n(Cc4ccccc4F)nnc3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N17 compound treatment 0.232 -0.00291 -0.16 -0.1562 -1.0 1987985 ChemDiv2_006991 COC(=O)C1CCN(CC1)c2cc(=O)n(c3ccccc3Cl)c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N18 compound treatment 0.426 0.191 10.27 10.269 1.0 1987986 ChemDiv2_006992 COc1ccc(cc1)n2nnc3c(=O)n(C/C=C/c4ccccc4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N19 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1987987 ChemDiv2_006993 Brc1ccc(cc1)n2c(=O)cc(NCc3cccs3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N20 compound treatment 0.273 0.0381 2.05 2.0471 1.0 1987988 ChemDiv2_006994 CCN1CCCC1CNC(=O)c2cc3c(=O)[nH]c4ccc(C)cc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N21 compound treatment 0.223 -0.0119 -0.64 -0.6398 -1.0 1987989 ChemDiv2_006995 Cc1ccc(cc1)n2c(=O)cc(NCc3cccnc3)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N22 compound treatment 0.264 0.0291 1.56 1.5634 1.0 1987990 ChemDiv2_006996 CCSc1nnc(Cn2c(=O)sc3ccccc23)n1CCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N23 mock treatment 0.224 -0.0109 -0.59 -0.5861 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 N24 mock treatment 0.222 -0.0129 -0.69 -0.6936 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O01 compound treatment 0.242 0.00709 0.38 0.3812 1.0 1987991 ChemDiv2_006997 CCOc1ccc2OC3(CCCCC3)CC(SCC(=O)N4CCC5(CC4)OCCO5)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O02 compound treatment 0.498 0.263 14.14 14.1381 1.0 1987992 ChemDiv2_006998 COc1ccc(cc1)N2CCN(CC2)C(=O)CCCc3cc(on3)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O03 compound treatment 0.241 0.00609 0.33 0.3275 1.0 1987993 ChemDiv2_006999 O=C(C1CCCN(C1)S(=O)(=O)c2c[nH]cn2)N3CCn4c3nc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O04 compound treatment 0.314 0.0791 4.25 4.2503 1.0 1987994 ChemDiv2_007000 CN(C)CCNC(=O)c1cc2c(=O)oc3ccc(C)cc3c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O05 compound treatment 0.258 0.0231 1.24 1.241 1.0 1987995 ChemDiv2_007001 O=C(Nc1nccs1)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O06 compound treatment 0.232 -0.00291 -0.16 -0.1562 -1.0 1987996 ChemDiv2_007002 Cc1ccc2oc(=O)c3cc(sc3c2c1)C(=O)NCCc4ccsc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O07 compound treatment 0.252 0.0171 0.92 0.9186 1.0 1987997 ChemDiv2_007003 CN(CC(=O)NC(c1ccccc1)c2ccccc2)S(=O)(=O)c3ccc4NC(=O)CCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O08 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1987998 ChemDiv2_007004 COc1ccc2cc3c(N)nn(C(=O)Cn4c(=O)oc5ccccc45)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O09 compound treatment 0.478 0.243 13.06 13.0633 1.0 1987999 ChemDiv2_007005 CCC(C)C(N1Cc2ccccc2C1=O)C(=O)Nc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O10 compound treatment 0.251 0.0161 0.86 0.8648 1.0 1988000 ChemDiv2_007006 CN(CC(=O)NC(c1ccccc1)c2ccccc2)S(=O)(=O)c3ccc4n(C)c(=O)n(C)c(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O11 compound treatment 0.257 0.0221 1.19 1.1873 1.0 1988001 ChemDiv2_007007 CC(C)NC(=O)CCc1c(C)nc2cc(nn2c1C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O12 compound treatment 0.445 0.21 11.29 11.29 1.0 1988002 ChemDiv2_007008 CN1CCN(CCCNC(=O)c2ccc3c(Cl)c4CCCCc4nc3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O13 compound treatment 0.437 0.202 10.86 10.8601 1.0 1988003 ChemDiv2_007009 CCOC(=O)c1ccc(NC(=O)CCc2c(C)nc3cc(nn3c2C)c4ccccc4OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O14 compound treatment 0.374 0.139 7.47 7.4746 1.0 1988004 ChemDiv2_007010 CC(C)N(Cc1nc(no1)c2ccccc2)C(=O)COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O15 compound treatment 0.245 0.0101 0.54 0.5424 1.0 1988005 ChemDiv2_007011 Cc1nc2ncnn2c(C)c1CCC(=O)NCc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O16 compound treatment 0.282 0.0471 2.53 2.5307 1.0 1988006 ChemDiv2_007012 CCOC(=O)Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O17 compound treatment 0.255 0.0201 1.08 1.0798 1.0 1988007 ChemDiv2_007013 CCOc1ccc2nc(NC(=O)C(CC(C)C)NS(=O)(=O)c3ccc4n(C)c(=O)oc4c3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O18 compound treatment 0.242 0.00709 0.38 0.3812 1.0 1988008 ChemDiv2_007014 CCCN(C(=O)c1oc(=O)c2ccccc2c1c3ccccc3)c4ccccc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O19 compound treatment 0.284 0.0491 2.64 2.6382 1.0 1988009 ChemDiv2_007015 CN(C1CCCCC1)C(=O)C(NS(=O)(=O)c2ccc3NC(=O)CCc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O20 compound treatment 0.432 0.197 10.59 10.5914 1.0 1988010 ChemDiv2_007016 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O21 compound treatment 0.234 -9.06E-4 -0.05 -0.0487 -1.0 1988011 ChemDiv2_007017 CCOc1ccc(cc1)C(=O)c2[nH]c(=O)c3ccccc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O22 compound treatment 0.229 -0.00591 -0.32 -0.3174 -1.0 1988012 ChemDiv2_007018 COc1ccc(cc1)c2nc(SCC(=O)N3CCCC3)c4c(=O)n(C)c(=O)n(C)c4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O23 mock treatment 0.235 9.37E-5 0.01 0.005 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 O24 mock treatment 0.235 9.37E-5 0.01 0.005 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P01 compound treatment 0.242 0.00709 0.38 0.3812 1.0 1988013 ChemDiv2_007019 COc1ccc(CCNC(=O)CSc2nc(nc3n(C)c(=O)n(C)c(=O)c23)c4cccs4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P02 compound treatment 0.463 0.228 12.26 12.2573 1.0 1988014 ChemDiv2_007020 CCOc1ccc(cc1)c2cc(CCCC(=O)NCc3ccccc3)no2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P03 compound treatment 0.24 0.00509 0.27 0.2737 1.0 1988015 ChemDiv2_007021 COc1ccc(Cn2c(CCC(=O)N3CCOCC3)nc4cccnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P04 compound treatment 0.36 0.125 6.72 6.7223 1.0 1988016 ChemDiv2_007022 CCC(=O)Nc1ccc(cc1)c2cn3cccnc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P05 compound treatment 0.226 -0.00891 -0.48 -0.4786 -1.0 1988017 ChemDiv2_007023 CN(C)CCNC(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P06 compound treatment 0.42 0.185 9.95 9.9466 1.0 1988018 ChemDiv2_007024 Cc1c(nc2ncccn12)c3cccc(NC(=O)c4ccccc4F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P07 compound treatment 0.222 -0.0129 -0.69 -0.6936 -1.0 1988019 ChemDiv2_007025 CC(C)N(C1CCCCC1)C(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P08 compound treatment 0.236 0.00109 0.06 0.0588 1.0 1988020 ChemDiv2_007026 COc1ccc(cc1)C2=NOC(C2)C(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P09 compound treatment 0.251 0.0161 0.86 0.8648 1.0 1988021 ChemDiv2_007027 CN(C1CCCCC1)C(=O)c2cc(C)no2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P10 compound treatment 0.376 0.141 7.58 7.5821 1.0 1988022 ChemDiv2_007028 COc1cccc(c1)C2=NOC(C2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P11 compound treatment 0.355 0.12 6.45 6.4536 1.0 1988023 ChemDiv2_007029 Cc1noc(C(=O)NCCc2ccccc2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P12 compound treatment 0.306 0.0711 3.82 3.8204 1.0 1988024 ChemDiv2_007030 COc1ccc(OC)c(c1)C2=NOC(C2)C(=O)Nc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P13 compound treatment 0.231 -0.00391 -0.21 -0.2099 -1.0 1988025 ChemDiv2_007031 Cc1nc2ccccc2c3oc(cc13)C(=O)NCCCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P14 compound treatment 0.325 0.0901 4.84 4.8414 1.0 1988026 ChemDiv2_007032 CCOC(=O)C(CC)n1cnc2n(Cc3ccc(C)cc3)nnc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P15 compound treatment 0.238 0.00309 0.17 0.1663 1.0 1988027 ChemDiv2_007033 COc1ccccc1OCCn2c(nc3ccccc23)C4CN(C(=O)C4)c5cccc(SC)c5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P16 compound treatment 0.237 0.00209 0.11 0.1125 1.0 1988028 ChemDiv2_007034 CCOC(=O)Cn1cnc2n(Cc3ccccc3F)nnc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P17 compound treatment 0.254 0.0191 1.03 1.0261 1.0 1988029 ChemDiv2_007035 Clc1ccccc1n2c(=O)cc([nH]c2=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P18 compound treatment 0.225 -0.00991 -0.53 -0.5323 -1.0 1988030 ChemDiv2_007036 COc1ccc(cc1)n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P19 compound treatment 0.21 -0.0249 -1.34 -1.3384 -1.0 1988031 ChemDiv2_007037 CC1CN(CC(C)O1)c2cc(=O)n(c3cc(Cl)ccc3C)c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P20 compound treatment 0.218 -0.0169 -0.91 -0.9085 -1.0 1988032 ChemDiv2_007038 CN(CCC#N)C(=O)Cn1ncc2c(=O)oc3ccccc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P21 compound treatment 0.216 -0.0189 -1.02 -1.016 -1.0 1988033 ChemDiv2_007039 O=c1cc([nH]c(=O)n1c2ccccc2)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P22 compound treatment 0.31 0.0751 4.04 4.0354 1.0 1988034 ChemDiv2_007040 COc1ccc(cc1)n2c(Cn3c(=O)sc4ccccc34)nnc2SCC(=O)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P23 mock treatment 0.224 -0.0109 -0.59 -0.5861 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1388 P24 mock treatment 0.231 -0.00391 -0.21 -0.2099 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A01 compound treatment 0.302 0.0586 3.15 3.1487 1.0 1988035 ChemDiv2_007041 Nc1cc(nn1S(=O)(=O)c2cccc3nsnc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A02 compound treatment 0.24 -0.00341 -0.18 -0.183 -1.0 1988036 ChemDiv2_007042 CCCCN(CC)C(=O)Cn1nc(Cc2ccncc2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A03 compound treatment 0.375 0.132 7.07 7.0716 1.0 1988037 ChemDiv2_007043 Clc1c2CCCc2nc3cc(ccc13)C(=O)NCC4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A04 compound treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1988038 ChemDiv2_007044 COC(=O)c1cc2OCOc2cc1NC(=O)Cn3nc(Cc4ccncc4)c5ccccc5c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A05 compound treatment 0.481 0.238 12.77 12.7678 1.0 1988039 ChemDiv2_007045 Cc1cc2nc(CSc3nnc(N)s3)cc(=O)n2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A06 compound treatment 0.232 -0.0114 -0.61 -0.6129 -1.0 1988040 ChemDiv2_007046 CN(C(=O)C1CCCN1S(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A07 compound treatment 0.461 0.218 11.69 11.693 1.0 1988041 ChemDiv2_007047 CCc1nn2c(=O)cc(CSc3nc(C)cc(=O)[nH]3)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A08 compound treatment 0.397 0.154 8.25 8.2538 1.0 1988042 ChemDiv2_007048 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc3SCCN(Cc4ccccc4)c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A09 compound treatment 0.231 -0.0124 -0.67 -0.6667 -1.0 1988043 ChemDiv2_007049 Cc1nc2c3ccccc3n4c(CCCC(=O)N5CCOCC5)nnc4n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A10 compound treatment 0.263 0.0196 1.05 1.0529 1.0 1988044 ChemDiv2_007050 CCN1CCSc2ccc(cc12)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A11 compound treatment 0.248 0.00459 0.25 0.2469 1.0 1988045 ChemDiv2_007051 O=C(N1CCCC1)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A12 compound treatment 0.281 0.0376 2.02 2.0202 1.0 1988046 ChemDiv2_007052 O=C(Cn1ncc2ccsc2c1=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A13 compound treatment 0.254 0.0106 0.57 0.5693 1.0 1988047 ChemDiv2_007053 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2c(oc3ccccc23)C(=O)Nc4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A14 compound treatment 0.208 -0.0354 -1.9 -1.9027 -1.0 1988048 ChemDiv2_007054 Cc1cc(C)c2c(=O)n(CC(=O)NCCCN3CCOCC3)sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A15 compound treatment 0.235 -0.00841 -0.45 -0.4517 -1.0 1988049 ChemDiv2_007055 O=C(NCc1ccco1)c2cnn3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A16 compound treatment 0.242 -0.00141 -0.08 -0.0756 -1.0 1988050 ChemDiv2_007056 Cc1ccc(Cn2c(cc3sccc23)C(=O)NCCCN4CCOCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A17 compound treatment 0.229 -0.0144 -0.77 -0.7742 -1.0 1988051 ChemDiv2_007057 CCOC(=O)c1cnn(CCOC(=O)C(C)(C)C)c1NC(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A18 compound treatment 0.243 -4.06E-4 -0.02 -0.0218 -1.0 1988052 ChemDiv2_007058 CC(C(=O)NCCCN1CCN(C)CC1)n2nc(c3ccccc3)c4cc(Cl)ccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A19 compound treatment 0.256 0.0126 0.68 0.6768 1.0 1988053 ChemDiv2_007059 CCOC(=O)N1CCc2c(C1)sc3n(C)c(=O)n(CCc4ccccc4)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A20 compound treatment 0.481 0.238 12.77 12.7678 1.0 1988054 ChemDiv2_007060 CN(CCc1ccccn1)C(=O)c2cc3COc4ccccc4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A21 compound treatment 0.452 0.209 11.21 11.2094 1.0 1988055 ChemDiv2_007061 CCOC(=O)N1CCN(CC1)c2nnc(Cc3cccnc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A22 compound treatment 0.296 0.0526 2.83 2.8263 1.0 1988056 ChemDiv2_007062 NS(=O)(=O)c1ccc(CCNc2ccc3nnc(c4ccccc4)n3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A23 mock treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 A24 mock treatment 0.246 0.00259 0.14 0.1394 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B01 compound treatment 0.316 0.0726 3.9 3.901 1.0 1988057 ChemDiv2_007063 CCn1ncc(C2=NOC(C2)C(=O)NCc3ccccc3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B02 compound treatment 0.248 0.00459 0.25 0.2469 1.0 1988058 ChemDiv2_007064 O=C(Cn1cccc1)NC2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B03 compound treatment 0.248 0.00459 0.25 0.2469 1.0 1988059 ChemDiv2_007065 CCOC(=O)c1[nH]c(C)c(C(=O)N2CCCCC2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B04 compound treatment 0.236 -0.00741 -0.4 -0.398 -1.0 1988060 ChemDiv2_007066 O=C(C1CCCN1S(=O)(=O)c2cccc3cccnc23)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B05 compound treatment 0.384 0.141 7.56 7.5552 1.0 1988061 ChemDiv2_007067 O=C(CSc1ncnc2ccccc12)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B06 compound treatment 0.44 0.197 10.56 10.5645 1.0 1988062 ChemDiv2_007068 Cc1nnc2ccc(NCCc3ccc(cc3)S(=O)(=O)N)nn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B07 compound treatment 0.262 0.0186 1.0 0.9992 1.0 1988063 ChemDiv2_007069 Cc1cccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)NCc4ccccc4)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B08 compound treatment 0.249 0.00559 0.3 0.3006 1.0 1988064 ChemDiv2_007070 COc1ccc(OC)c(CCNc2ccc3nncn3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B09 compound treatment 0.249 0.00559 0.3 0.3006 1.0 1988065 ChemDiv2_007071 CCOC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B10 compound treatment 0.472 0.229 12.28 12.2842 1.0 1988066 ChemDiv2_007072 C(Sc1ccc2nnc(c3ccccc3)n2n1)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B11 compound treatment 0.479 0.236 12.66 12.6603 1.0 1988067 ChemDiv2_007073 CC(CCc1ccco1)NC(=O)c2cc3c(=O)[nH]c4ccc(C)cc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B12 compound treatment 0.247 0.00359 0.19 0.1931 1.0 1988068 ChemDiv2_007074 CN(Cc1ccccc1)S(=O)(=O)c2ccc3NC(=O)CNC(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B13 compound treatment 0.232 -0.0114 -0.61 -0.6129 -1.0 1988069 ChemDiv2_007075 Cc1ccc(CNC(=O)Cn2ncc3COc4ccccc4-c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B14 compound treatment 0.226 -0.0174 -0.94 -0.9354 -1.0 1988070 ChemDiv2_007076 CC1CCCCC1NC(=O)CC2Oc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B15 compound treatment 0.3 0.0566 3.04 3.0412 1.0 1988071 ChemDiv2_007077 C1CN(c2nc3ccccc3n4cnnc24)c5ccccc5C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B16 compound treatment 0.323 0.0796 4.28 4.2772 1.0 1988072 ChemDiv2_007078 CCOc1ccc(cc1OCC)C(=O)N(C2CS(=O)(=O)C=C2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B17 compound treatment 0.29 0.0466 2.5 2.5039 1.0 1988073 ChemDiv2_007079 CC(C)Nc1nc2ccccc2n3cnnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B18 compound treatment 0.237 -0.00641 -0.34 -0.3443 -1.0 1988074 ChemDiv2_007080 CCN(CCN(C)C)C(=O)Cn1ncc2COc3ccc(C)cc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B19 compound treatment 0.307 0.0636 3.42 3.4174 1.0 1988075 ChemDiv2_007081 COc1cc(NC(=O)C(Cc2ccccc2)n3cccc3)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B20 compound treatment 0.286 0.0426 2.29 2.2889 1.0 1988076 ChemDiv2_007082 CC(C)NC(=O)c1cc2CS(=O)(=O)Cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B21 compound treatment 0.246 0.00259 0.14 0.1394 1.0 1988077 ChemDiv2_007083 CN(Cc1ccccc1)C(=O)Cn2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B22 compound treatment 0.279 0.0356 1.91 1.9127 1.0 1988078 ChemDiv2_007084 CC1(C)CC(=O)N(CC(=O)Nc2ccc3OCCOc3c2)c4ccccc4S1(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B23 mock treatment 0.249 0.00559 0.3 0.3006 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 B24 mock treatment 0.236 -0.00741 -0.4 -0.398 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C01 compound treatment 0.302 0.0586 3.15 3.1487 1.0 1988079 ChemDiv2_007085 CCOc1ccc(cc1)c2cc(N)n(n2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C02 compound treatment 0.266 0.0226 1.21 1.2141 1.0 1988080 ChemDiv2_007086 COc1ccc(N(C)C(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C03 compound treatment 0.386 0.143 7.66 7.6627 1.0 1988081 ChemDiv2_007087 Clc1c2CCCc2nc3cc(ccc13)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C04 compound treatment 0.314 0.0706 3.79 3.7936 1.0 1988082 ChemDiv2_007088 CCCCN(Cc1ccco1)C(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C05 compound treatment 0.387 0.144 7.72 7.7164 1.0 1988083 ChemDiv2_007089 Cc1cc2nc(CSc3nc4sc5CCCCc5c4c(=O)n3C)cc(=O)n2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C06 compound treatment 0.258 0.0146 0.78 0.7842 1.0 1988084 ChemDiv2_007090 CN(CC(=O)NC1CCCCCC1)S(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C07 compound treatment 0.536 0.293 15.72 15.7234 1.0 1988085 ChemDiv2_007091 CCc1nn2c(=O)cc(CSc3nc4sc5CCCCc5c4c(=O)n3C)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C08 compound treatment 0.243 -4.06E-4 -0.02 -0.0218 -1.0 1988086 ChemDiv2_007092 CCN1CCN(CCCNC(=O)c2ccc3SCCN(Cc4ccccc4)c3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C09 compound treatment 0.295 0.0516 2.77 2.7725 1.0 1988087 ChemDiv2_007093 Cc1nc2c3ccccc3n4c(CCCC(=O)NCCc5ccccc5)nnc4n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C10 compound treatment 0.319 0.0756 4.06 4.0623 1.0 1988088 ChemDiv2_007094 COc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NCCCN3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C11 compound treatment 0.33 0.0866 4.65 4.6534 1.0 1988089 ChemDiv2_007095 Fc1ccc(NC(=O)Cc2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C12 compound treatment 0.234 -0.00941 -0.51 -0.5055 -1.0 1988090 ChemDiv2_007096 O=C(Cn1ncc2ccsc2c1=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C13 compound treatment 0.355 0.112 6.0 5.9968 1.0 1988091 ChemDiv2_007097 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)COC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C14 compound treatment 0.234 -0.00941 -0.51 -0.5055 -1.0 1988092 ChemDiv2_007098 Cc1ccc(CNC(=O)Cn2sc3nc(C)cc(C)c3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C15 compound treatment 0.244 5.94E-4 0.03 0.0319 1.0 1988093 ChemDiv2_007099 CC1CCN(CC1)C(=O)c2cnn3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C16 compound treatment 0.331 0.0876 4.71 4.7071 1.0 1988094 ChemDiv2_007100 Cn1c(cc2sccc12)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C17 compound treatment 0.32 0.0766 4.12 4.116 1.0 1988095 ChemDiv2_007101 Cn1c(=O)[nH]c(=O)c2n(Cc3ccc(Cl)cc3)c(CN4CCN(Cc5ccccc5)CC4)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C18 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988096 ChemDiv2_007102 COc1ccc2n(C)c3c(=O)n(CCO)c(SCC(=O)c4ccccc4)nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C19 compound treatment 0.377 0.134 7.18 7.179 1.0 1988097 ChemDiv2_007103 Cc1nc2c3ccccc3n(CC#N)c(=O)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C20 compound treatment 0.478 0.235 12.61 12.6066 1.0 1988098 ChemDiv2_007104 O=C(NCCCN1CCCCCC1)c2cc3COc4ccccc4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C21 compound treatment 0.412 0.169 9.06 9.0599 1.0 1988099 ChemDiv2_007105 C(N1CCN(CC1)c2nnc(Cc3cccnc3)c4ccccc24)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C22 compound treatment 0.26 0.0166 0.89 0.8917 1.0 1988100 ChemDiv2_007106 CN(CCNc1ccc2nnc(c3ccccc3)n2n1)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C23 mock treatment 0.243 -4.06E-4 -0.02 -0.0218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 C24 mock treatment 0.25 0.00659 0.35 0.3543 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D01 compound treatment 0.339 0.0956 5.14 5.137 1.0 1988101 ChemDiv2_007107 CCn1ncc(C2=NOC(C2)C(=O)Nc3c(C)nn(Cc4ccc(F)cc4)c3C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D02 compound treatment 0.242 -0.00141 -0.08 -0.0756 -1.0 1988102 ChemDiv2_007108 O=C(Cn1cccc1)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D03 compound treatment 0.379 0.136 7.29 7.2865 1.0 1988103 ChemDiv2_007109 CCOC(=O)c1c(C)c(C(=O)N(C)C2CCCCC2)c(C)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D04 compound treatment 0.274 0.0306 1.64 1.644 1.0 1988104 ChemDiv2_007110 CCOc1ccc(OCC)c(NC(=O)C2CCCN2S(=O)(=O)c3cccc4cccnc34)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D05 compound treatment 0.286 0.0426 2.29 2.2889 1.0 1988105 ChemDiv2_007111 CC(=O)N1CCc2c(C1)sc3n(Cc4ccccc4F)c(=O)n(c5ccccc5)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D06 compound treatment 0.386 0.143 7.66 7.6627 1.0 1988106 ChemDiv2_007112 Cc1nnc2ccc(NCc3ccccc3)nn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D07 compound treatment 0.359 0.116 6.21 6.2118 1.0 1988107 ChemDiv2_007113 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3n(CC(=O)NCCc4ccccc4)c(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D08 compound treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1988108 ChemDiv2_007114 C(Nc1ccc2nncn2n1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D09 compound treatment 0.31 0.0666 3.58 3.5786 1.0 1988109 ChemDiv2_007115 COc1ccc(CCn2c(=O)n(Cc3ccc(C#N)cc3)c4ncccc4c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D10 compound treatment 0.5 0.257 13.79 13.7888 1.0 1988110 ChemDiv2_007116 C(Sc1ccc2nnc(c3ccccc3)n2n1)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D11 compound treatment 0.228 -0.0154 -0.83 -0.8279 -1.0 1988111 ChemDiv2_007117 CC(C)NC(=O)Cn1ncc2COc3ccccc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D12 compound treatment 0.259 0.0156 0.84 0.838 1.0 1988112 ChemDiv2_007118 O=C(CN1C(=O)CCSc2ccccc12)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D13 compound treatment 0.247 0.00359 0.19 0.1931 1.0 1988113 ChemDiv2_007119 O=C(Cn1ncc2COc3ccccc3-c21)Nc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D14 compound treatment 0.326 0.0826 4.44 4.4384 1.0 1988114 ChemDiv2_007120 Cc1ccc2nc(NC(=O)CC3Oc4ccccc4NC3=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D15 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988115 ChemDiv2_007121 CN(c1cccc(C)c1)c2nc3ccccc3n4cnnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D16 compound treatment 0.237 -0.00641 -0.34 -0.3443 -1.0 1988116 ChemDiv2_007122 O=C(C1CCCC1)N(C2CS(=O)(=O)C=C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D17 compound treatment 0.506 0.263 14.11 14.1112 1.0 1988117 ChemDiv2_007123 CC(C)N(CCNc1nc2ccccc2c3nc(nn13)c4cccnc4)Cc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D18 compound treatment 0.322 0.0786 4.22 4.2235 1.0 1988118 ChemDiv2_007124 Cc1ccc(CCNC(=O)Cn2ncc3COc4ccc(C)cc4-c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D19 compound treatment 0.285 0.0416 2.24 2.2352 1.0 1988119 ChemDiv2_007125 O=C(C(Cc1ccccc1)n2cccc2)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D20 compound treatment 0.305 0.0616 3.31 3.3099 1.0 1988120 ChemDiv2_007126 CC(C)CCNC(=O)c1cc2CS(=O)(=O)Cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D21 compound treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1988121 ChemDiv2_007127 Fc1ccc(NC(=O)Cn2cccc2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D22 compound treatment 0.251 0.00759 0.41 0.4081 1.0 1988122 ChemDiv2_007128 Cc1cc(F)ccc1NC(=O)CN2C(=O)CC(C)(C)S(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D23 mock treatment 0.233 -0.0104 -0.56 -0.5592 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 D24 mock treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E01 compound treatment 0.277 0.0336 1.81 1.8053 1.0 1988123 ChemDiv2_007129 CCCS(=O)(=O)n1nc(cc1N)c2ccc(OC)cc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E02 compound treatment 0.425 0.182 9.76 9.7585 1.0 1988124 ChemDiv2_007130 COc1ccc(Cl)cc1N(C)C(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E03 compound treatment 0.372 0.129 6.91 6.9104 1.0 1988125 ChemDiv2_007131 CN(C(=O)c1ccc2c(Cl)c3CCCc3nc2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E04 compound treatment 0.271 0.0276 1.48 1.4828 1.0 1988126 ChemDiv2_007132 COc1ccc(OC)c(CCNC(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E05 compound treatment 0.339 0.0956 5.14 5.137 1.0 1988127 ChemDiv2_007133 Clc1ccc(SCc2cc(=O)n3ccsc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E06 compound treatment 0.38 0.137 7.34 7.3403 1.0 1988128 ChemDiv2_007134 CN(CC(=O)NCc1cccs1)S(=O)(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E07 compound treatment 0.41 0.167 8.95 8.9524 1.0 1988129 ChemDiv2_007135 C1CN(CCO1)c2nc3c(nnn3c4ccccc24)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E08 compound treatment 0.266 0.0226 1.21 1.2141 1.0 1988130 ChemDiv2_007136 O=C(N1CCCCC1)c2ccc3SCCN(Cc4ccccc4)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E09 compound treatment 0.225 -0.0184 -0.99 -0.9891 -1.0 1988131 ChemDiv2_007137 Cc1nc2c3ccccc3n4c(CCCC(=O)N5CCC(CC5)C(=O)N)nnc4n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E10 compound treatment 0.53 0.287 15.4 15.4009 1.0 1988132 ChemDiv2_007138 O=C(CCCn1nc(c2ccccc2)c3ccccc13)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E11 compound treatment 0.235 -0.00841 -0.45 -0.4517 -1.0 1988133 ChemDiv2_007139 Cc1ccc(NC(=O)Cc2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E12 compound treatment 0.28 0.0366 1.97 1.9665 1.0 1988134 ChemDiv2_007140 CN(Cc1ccccc1)C(=O)Cn2ncc3ccsc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E13 compound treatment 0.274 0.0306 1.64 1.644 1.0 1988135 ChemDiv2_007141 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c4cccs4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E14 compound treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1988136 ChemDiv2_007142 Cc1cc(C)c2c(=O)n(CC(=O)N3CCCCC3)sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E15 compound treatment 0.251 0.00759 0.41 0.4081 1.0 1988137 ChemDiv2_007143 O=C(N1CCN(CC1)C2CCCCC2)c3cnn4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E16 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988138 ChemDiv2_007144 CC1CCCCC1NC(=O)c2cc3sccc3n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E17 compound treatment 0.357 0.114 6.1 6.1043 1.0 1988139 ChemDiv2_007145 Cn1c(=O)[nH]c(=O)c2n(CCc3ccccc3)c(CN4CCN(CC4)c5ccccc5F)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E18 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988140 ChemDiv2_007146 COc1ccc2n(C)c3c(=O)n(CCO)c(SCC(C)C)nc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E19 compound treatment 0.328 0.0846 4.55 4.5459 1.0 1988141 ChemDiv2_007147 Cc1cc(C)n(CCc2nc3c4ccccc4n(CC#N)c(=O)n3n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E20 compound treatment 0.551 0.308 16.53 16.5294 1.0 1988142 ChemDiv2_007148 O=C(Nc1cccc(C#N)c1)c2cc3COc4ccccc4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E21 compound treatment 0.56 0.317 17.01 17.0131 1.0 1988143 ChemDiv2_007149 C(c1cccnc1)c2nnc(N3CCN(CC3)c4ccccn4)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E22 compound treatment 0.369 0.126 6.75 6.7491 1.0 1988144 ChemDiv2_007150 CCN(CC)CCNc1ccc2nnc(c3ccc(F)cc3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E23 mock treatment 0.252 0.00859 0.46 0.4618 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 E24 mock treatment 0.251 0.00759 0.41 0.4081 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F01 compound treatment 0.498 0.255 13.68 13.6813 1.0 1988145 ChemDiv2_007151 Clc1ccccc1NC(=O)CSc2ncc(c(=O)[nH]2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F02 compound treatment 0.367 0.124 6.64 6.6417 1.0 1988146 ChemDiv2_007152 Cc1ccc2nc(NC(=O)Cn3cccc3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F03 compound treatment 0.262 0.0186 1.0 0.9992 1.0 1988147 ChemDiv2_007153 CCOC(=O)c1c(C)c(C(=O)N2CCCCC2)c(C)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F04 compound treatment 0.249 0.00559 0.3 0.3006 1.0 1988148 ChemDiv2_007154 O=C(NCc1ccccc1)C2CCCN2S(=O)(=O)c3cccc4cccnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F05 compound treatment 0.296 0.0526 2.83 2.8263 1.0 1988149 ChemDiv2_007155 CC(=O)N1CCc2c(C1)sc3n(Cc4ccccc4C#N)c(=O)n(c5ccccc5)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F06 compound treatment 0.299 0.0556 2.99 2.9875 1.0 1988150 ChemDiv2_007156 C(Nc1ccc2nncn2n1)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F07 compound treatment 0.455 0.212 11.37 11.3706 1.0 1988151 ChemDiv2_007157 O=C(Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCc4ccccc34)NC5CCCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F08 compound treatment 0.268 0.0246 1.32 1.3216 1.0 1988152 ChemDiv2_007158 CC1CC(C)CN(C1)c2ccc3nncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F09 compound treatment 0.431 0.188 10.08 10.0809 1.0 1988153 ChemDiv2_007159 Fc1cccc(Cn2c(=O)n(CCc3c[nH]c4ccccc34)c(=O)c5cccnc25)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F10 compound treatment 0.46 0.217 11.64 11.6393 1.0 1988154 ChemDiv2_007160 COC(=O)CSc1ccc2nnc(c3ccccc3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F11 compound treatment 0.254 0.0106 0.57 0.5693 1.0 1988155 ChemDiv2_007161 O=C(Cn1ncc2COc3ccccc3-c21)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F12 compound treatment 0.292 0.0486 2.61 2.6113 1.0 1988156 ChemDiv2_007162 O=C(CN1C(=O)CCSc2ccccc12)NCCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F13 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988157 ChemDiv2_007163 NS(=O)(=O)c1ccc(NC(=O)Cn2ncc3COc4ccccc4-c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F14 compound treatment 0.388 0.145 7.77 7.7702 1.0 1988158 ChemDiv2_007164 CCOc1ccc(OCC)c(NC(=O)CC2Oc3ccccc3NC2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F15 compound treatment 0.297 0.0536 2.88 2.88 1.0 1988159 ChemDiv2_007165 CCN(c1ccccc1)c2nc3ccccc3n4cnnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F16 compound treatment 0.496 0.253 13.57 13.5739 1.0 1988160 ChemDiv2_007166 O=C(N(C1CS(=O)(=O)C=C1)c2ccccc2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F17 compound treatment 0.293 0.0496 2.67 2.6651 1.0 1988161 ChemDiv2_007167 COc1cc2nc(NCc3ccccc3)n4nc(nc4c2cc1OC)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F18 compound treatment 0.456 0.213 11.42 11.4243 1.0 1988162 ChemDiv2_007168 CCc1nnc(NC(=O)Cn2ncc3COc4ccc(C)cc4-c32)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F19 compound treatment 0.261 0.0176 0.95 0.9455 1.0 1988163 ChemDiv2_007169 Cc1ccc(CNC(=O)C(Cc2ccccc2)n3cccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F20 compound treatment 0.281 0.0376 2.02 2.0202 1.0 1988164 ChemDiv2_007170 CCN1CCCC1CNC(=O)c2cc3CS(=O)(=O)Cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F21 compound treatment 0.256 0.0126 0.68 0.6768 1.0 1988165 ChemDiv2_007171 CCc1ccc(NC(=O)Cn2cccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F22 compound treatment 0.254 0.0106 0.57 0.5693 1.0 1988166 ChemDiv2_007172 COc1ccc(OC)c(CCNC(=O)CN2C(=O)CC(C)(C)S(=O)(=O)c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F23 mock treatment 0.234 -0.00941 -0.51 -0.5055 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 F24 mock treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G01 compound treatment 0.35 0.107 5.73 5.7281 1.0 1988167 ChemDiv2_007173 Oc1ccccc1Cc2c(O)nc3SCCCn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G02 compound treatment 0.257 0.0136 0.73 0.7305 1.0 1988168 ChemDiv2_007174 CN(C(=O)Cn1nc(Cc2ccncc2)c3ccccc3c1=O)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G03 compound treatment 0.559 0.316 16.96 16.9593 1.0 1988169 ChemDiv2_007175 Clc1c2CCCc2nc3cc(ccc13)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G04 compound treatment 0.287 0.0436 2.34 2.3426 1.0 1988170 ChemDiv2_007176 O=C(Cn1nc(Cc2cccnc2)c3ccccc3c1=O)NCC4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G05 compound treatment 0.268 0.0246 1.32 1.3216 1.0 1988171 ChemDiv2_007177 OC(=O)c1ccccc1SCc2cc(=O)n3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G06 compound treatment 0.272 0.0286 1.54 1.5366 1.0 1988172 ChemDiv2_007178 CCn1c(=O)c(=O)n(CC)c2cc(ccc12)S(=O)(=O)NCc3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G07 compound treatment 0.44 0.197 10.56 10.5645 1.0 1988173 ChemDiv2_007179 CC(=O)NCCNc1nc2c(nnn2c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G08 compound treatment 0.333 0.0896 4.81 4.8146 1.0 1988174 ChemDiv2_007180 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc3SCCN(Cc4ccc(C)cc4)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G09 compound treatment 0.251 0.00759 0.41 0.4081 1.0 1988175 ChemDiv2_007181 Cc1nc2c3ccccc3n4c(CCCC(=O)NCC5CCCO5)nnc4n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G10 compound treatment 0.394 0.151 8.09 8.0926 1.0 1988176 ChemDiv2_007182 COc1ccc(cc1OC)C2OC(=O)CC2C(=O)N3CCN(CC3)c4cc(Cl)ccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G11 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988177 ChemDiv2_007183 CN(C1CCCCC1)C(=O)Cc2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G12 compound treatment 0.359 0.116 6.21 6.2118 1.0 1988178 ChemDiv2_007184 O=C(Cn1ncc2ccsc2c1=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G13 compound treatment 0.284 0.0406 2.18 2.1814 1.0 1988179 ChemDiv2_007185 O=c1n(Cc2ccccn2)c(=O)c3sc4ccccc4c3n1CCN5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G14 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988180 ChemDiv2_007186 CCCNC(=O)Cn1sc2nc(C)cc(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G15 compound treatment 0.514 0.271 14.54 14.5411 1.0 1988181 ChemDiv2_007187 CCOC(=O)c1ccc(NC(=O)c2cnn3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G16 compound treatment 0.257 0.0136 0.73 0.7305 1.0 1988182 ChemDiv2_007188 CCn1c(cc2sccc12)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G17 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988183 ChemDiv2_007189 Cn1c(=O)[nH]c(=O)c2n(CCCc3ccccc3)c(CN4CCOCC4)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G18 compound treatment 0.454 0.211 11.32 11.3169 1.0 1988184 ChemDiv2_007190 Cc1cc(NC(=O)c2cc3COc4cccc(C)c4-c3s2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G19 compound treatment 0.288 0.0446 2.4 2.3964 1.0 1988185 ChemDiv2_007191 Cc1cc(C)n(CCc2nc3c4ccccc4n(Cc5ccc(F)cc5)c(=O)n3n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G20 compound treatment 0.396 0.153 8.2 8.2001 1.0 1988186 ChemDiv2_007192 Cc1ccc(CNC(=O)c2cc3COc4ccccc4-c3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G21 compound treatment 0.486 0.243 13.04 13.0365 1.0 1988187 ChemDiv2_007193 C(c1cccnc1)c2nnc(N3CCC4(CC3)OCCO4)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G22 compound treatment 0.331 0.0876 4.71 4.7071 1.0 1988188 ChemDiv2_007194 CN(C1CCCC1)C2CCN(CC2)c3ccc4nnc(c5ccc(F)cc5)n4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G23 mock treatment 0.243 -4.06E-4 -0.02 -0.0218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 G24 mock treatment 0.244 5.94E-4 0.03 0.0319 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H01 compound treatment 0.493 0.25 13.41 13.4126 1.0 1988189 ChemDiv2_007195 COc1ccc(NC(=O)CSc2ncc(c(=O)[nH]2)S(=O)(=O)c3ccccc3)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H02 compound treatment 0.247 0.00359 0.19 0.1931 1.0 1988190 ChemDiv2_007196 Cc1cccc(NC(=O)Cn2cccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H03 compound treatment 0.391 0.148 7.93 7.9314 1.0 1988191 ChemDiv2_007197 Fc1ccccc1CSc2nc3ncccc3c(=O)n2Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H04 compound treatment 0.292 0.0486 2.61 2.6113 1.0 1988192 ChemDiv2_007198 CN(CC(=O)Nc1nc(C)cs1)S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H05 compound treatment 0.255 0.0116 0.62 0.623 1.0 1988193 ChemDiv2_007199 COc1ccccc1NC(=O)Cn2c(=O)n(c3ccccc3)c(=O)c4c5CCN(Cc5sc24)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H06 compound treatment 0.358 0.115 6.16 6.158 1.0 1988194 ChemDiv2_007200 C(Cc1ccccc1)Nc2ccc3nncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H07 compound treatment 0.413 0.17 9.11 9.1136 1.0 1988195 ChemDiv2_007201 Cc1ccnc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCc5ccccc45)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H08 compound treatment 0.445 0.202 10.83 10.8332 1.0 1988196 ChemDiv2_007202 Cc1nnc2ccc(nn12)N3CCC(C3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H09 compound treatment 0.381 0.138 7.39 7.394 1.0 1988197 ChemDiv2_007203 Cc1ccc2[nH]c(=O)c3cc(sc3c2c1)C(=O)N4CCCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H10 compound treatment 0.406 0.163 8.74 8.7374 1.0 1988198 ChemDiv2_007204 COC(=O)C(C)Sc1ccc2nnc(c3ccccc3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H11 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988199 ChemDiv2_007205 O=C(Cn1ncc2COc3ccccc3-c21)NCCCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H12 compound treatment 0.253 0.00959 0.52 0.5155 1.0 1988200 ChemDiv2_007206 O=C(CN1C(=O)CCSc2ccccc12)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H13 compound treatment 0.262 0.0186 1.0 0.9992 1.0 1988201 ChemDiv2_007207 O=C(Cn1ncc2COc3ccccc3-c21)NCCc4ccsc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H14 compound treatment 0.384 0.141 7.56 7.5552 1.0 1988202 ChemDiv2_007208 O=C(CC1Oc2ccccc2NC1=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H15 compound treatment 0.3 0.0566 3.04 3.0412 1.0 1988203 ChemDiv2_007209 C1CC1Nc2nc3ccccc3n4cnnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H16 compound treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1988204 ChemDiv2_007210 CCC(=O)N(C1CS(=O)(=O)C=C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H17 compound treatment 0.254 0.0106 0.57 0.5693 1.0 1988205 ChemDiv2_007211 COc1cc2nc(NCCCN3CCCCC3C)n4nc(nc4c2cc1OC)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H18 compound treatment 0.37 0.127 6.8 6.8029 1.0 1988206 ChemDiv2_007212 COC(=O)c1sccc1NC(=O)Cn2ncc3COc4ccc(C)cc4-c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H19 compound treatment 0.27 0.0266 1.43 1.4291 1.0 1988207 ChemDiv2_007213 O=C(NCc1ccc2OCOc2c1)C(Cc3ccccc3)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H20 compound treatment 0.271 0.0276 1.48 1.4828 1.0 1988208 ChemDiv2_007214 CC1CCCCC1NC(=O)c2cc3CS(=O)(=O)Cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H21 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988209 ChemDiv2_007215 Cc1ccc(CNC(=O)Cn2cccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H22 compound treatment 0.292 0.0486 2.61 2.6113 1.0 1988210 ChemDiv2_007216 Fc1ccccc1Cn2c(nc3ccccc23)N4CCC(CC4)C(=O)NCc5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H23 mock treatment 0.247 0.00359 0.19 0.1931 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 H24 mock treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I01 compound treatment 0.246 0.00259 0.14 0.1394 1.0 1988211 ChemDiv2_007217 COC(=O)c1ccccc1NC(=O)c2ccc3c(Cl)c4CCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I02 compound treatment 0.276 0.0326 1.75 1.7515 1.0 1988212 ChemDiv2_007218 Clc1ccc(CCNC(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I03 compound treatment 0.32 0.0766 4.12 4.116 1.0 1988213 ChemDiv2_007219 OC(=O)CSc1c2CCCc2nc3cc(ccc13)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I04 compound treatment 0.291 0.0476 2.56 2.5576 1.0 1988214 ChemDiv2_007220 C=CCN(C(=O)Cn1nc(Cc2cccnc2)c3ccccc3c1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I05 compound treatment 0.329 0.0856 4.6 4.5996 1.0 1988215 ChemDiv2_007221 O=c1cc(CSc2nc3ccccc3[nH]2)nc4sccn14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I06 compound treatment 0.397 0.154 8.25 8.2538 1.0 1988216 ChemDiv2_007222 O=C(NCc1ccccn1)c2ccc3SCCN(Cc4ccccc4)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I07 compound treatment 0.379 0.136 7.29 7.2865 1.0 1988217 ChemDiv2_007223 O=C(Cn1c(=O)c2ccccc2n3nncc13)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I08 compound treatment 0.343 0.0996 5.35 5.352 1.0 1988218 ChemDiv2_007224 Cc1ccc(CN2CCSc3ccc(cc23)C(=O)NCCCN4CCOCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I09 compound treatment 0.235 -0.00841 -0.45 -0.4517 -1.0 1988219 ChemDiv2_007225 CC(C)NC(=O)CCCc1nnc2n3nc(C)nc3c4ccccc4n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I10 compound treatment 0.255 0.0116 0.62 0.623 1.0 1988220 ChemDiv2_007226 O=C(CC1Oc2ccccc2NC1=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I11 compound treatment 0.272 0.0286 1.54 1.5366 1.0 1988221 ChemDiv2_007227 COc1cccc(NC(=O)c2oc3ccccc3c2NC(=O)C4CCCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I12 compound treatment 0.351 0.108 5.78 5.7819 1.0 1988222 ChemDiv2_007228 O=C(Cn1ncc2ccsc2c1=O)N3CCC(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I13 compound treatment 0.272 0.0286 1.54 1.5366 1.0 1988223 ChemDiv2_007229 COCCn1c(=O)n(CCN2CCOCC2)c3c4ccccc4sc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I14 compound treatment 0.249 0.00559 0.3 0.3006 1.0 1988224 ChemDiv2_007230 CC1=C(c2ccc(C)cc2)S(=O)(=O)N=C1NCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I15 compound treatment 0.39 0.147 7.88 7.8776 1.0 1988225 ChemDiv2_007231 O=C(NCCc1ccccc1)c2cnn3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I16 compound treatment 0.288 0.0446 2.4 2.3964 1.0 1988226 ChemDiv2_007232 CCn1c(cc2sccc12)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I17 compound treatment 0.397 0.154 8.25 8.2538 1.0 1988227 ChemDiv2_007233 CCOC(=O)Cn1c(CN2CCN(CC2)c3cccc(Cl)c3)nc4n(C)c(=O)[nH]c(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I18 compound treatment 0.53 0.287 15.4 15.4009 1.0 1988228 ChemDiv2_007234 Cc1csc(NC(=O)c2cc3COc4cccc(C)c4-c3s2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I19 compound treatment 0.274 0.0306 1.64 1.644 1.0 1988229 ChemDiv2_007235 Cc1cc(C)n(CCc2nc3c4ccccc4n(CC(=O)Nc5ccc(Cl)cc5F)c(=O)n3n2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I20 compound treatment 0.55 0.307 16.48 16.4757 1.0 1988230 ChemDiv2_007236 O=C(NCCc1c[nH]c2ccccc12)c3cc4COc5ccccc5-c4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I21 compound treatment 0.265 0.0216 1.16 1.1604 1.0 1988231 ChemDiv2_007237 C(c1ccncc1)c2nnc(N3CCC(CC3)N4CCCCC4)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I22 compound treatment 0.376 0.133 7.13 7.1253 1.0 1988232 ChemDiv2_007238 Fc1cccc(F)c1C(=O)N2CCN(CC2)c3ccc4nnc(c5ccccc5)n4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I23 mock treatment 0.242 -0.00141 -0.08 -0.0756 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 I24 mock treatment 0.259 0.0156 0.84 0.838 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J01 compound treatment 0.553 0.31 16.64 16.6369 1.0 1988233 ChemDiv2_007239 CCOC(=O)c1ccc(NC(=O)CSc2ncc(c(=O)[nH]2)S(=O)(=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J02 compound treatment 0.337 0.0936 5.03 5.0295 1.0 1988234 ChemDiv2_007240 O=C(NCCc1ccccc1)C2CCC(CNS(=O)(=O)c3cccc4cccnc34)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J03 compound treatment 0.322 0.0786 4.22 4.2235 1.0 1988235 ChemDiv2_007241 CCC(Sc1nc2ncccc2c(=O)n1Cc3ccccc3)C(=O)Nc4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J04 compound treatment 0.274 0.0306 1.64 1.644 1.0 1988236 ChemDiv2_007242 CN(CC(=O)N1CCCCCC1)S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J05 compound treatment 0.393 0.15 8.04 8.0389 1.0 1988237 ChemDiv2_007243 O=C(Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCCC3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J06 compound treatment 0.252 0.00859 0.46 0.4618 1.0 1988238 ChemDiv2_007244 C(CN1CCOCC1)Nc2ccc3nncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J07 compound treatment 0.408 0.165 8.84 8.8449 1.0 1988239 ChemDiv2_007245 CCOC(=O)Cn1c(=O)n(Cc2ccc(C)cc2)c(=O)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J08 compound treatment 0.471 0.228 12.23 12.2304 1.0 1988240 ChemDiv2_007246 CSc1ccc2nnc(c3ccccc3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J09 compound treatment 0.444 0.201 10.78 10.7795 1.0 1988241 ChemDiv2_007247 CN(C(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J10 compound treatment 0.392 0.149 7.99 7.9851 1.0 1988242 ChemDiv2_007248 O=C(CSc1ccc2nnc(c3ccccc3)n2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J11 compound treatment 0.372 0.129 6.91 6.9104 1.0 1988243 ChemDiv2_007249 CCCN(C(=O)Cn1ncc2COc3ccccc3-c21)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J12 compound treatment 0.277 0.0336 1.81 1.8053 1.0 1988244 ChemDiv2_007250 O=C(CN1C(=O)CCSc2ccccc12)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J13 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988245 ChemDiv2_007251 Cc1ccc(cc1Nc2nc3ccccc3n4cnnc24)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J14 compound treatment 0.327 0.0836 4.49 4.4922 1.0 1988246 ChemDiv2_007252 O=C(CC1Oc2ccccc2NC1=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J15 compound treatment 0.414 0.171 9.17 9.1674 1.0 1988247 ChemDiv2_007253 O=C1CCCN1CCCNc2nc3ccccc3n4cnnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J16 compound treatment 0.255 0.0116 0.62 0.623 1.0 1725436 ChemDiv2_007254 O=C(N(C1CS(=O)(=O)C=C1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J17 compound treatment 0.31 0.0666 3.58 3.5786 1.0 1988248 ChemDiv2_007255 O=C(Nc1nccs1)C(Cc2ccccc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J18 compound treatment 0.264 0.0206 1.11 1.1067 1.0 1988249 ChemDiv2_007256 COC(=O)c1cc2OCOc2cc1NC(=O)Cn3ncc4COc5ccc(C)cc5-c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J19 compound treatment 0.263 0.0196 1.05 1.0529 1.0 1988250 ChemDiv2_007257 O=C(NCc1cccs1)C(Cc2ccccc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J20 compound treatment 0.419 0.176 9.44 9.436 1.0 1988251 ChemDiv2_007258 COc1ccc(OC)c(NC(=O)CN2C(=O)CC(C)(C)Sc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J21 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988252 ChemDiv2_007259 O=C(Cn1cccc1)N2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J22 compound treatment 0.253 0.00959 0.52 0.5155 1.0 1988253 ChemDiv2_007260 CCCNC(=O)C1CCN(CC1)c2nc3ccccc3n2Cc4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J23 mock treatment 0.24 -0.00341 -0.18 -0.183 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 J24 mock treatment 0.242 -0.00141 -0.08 -0.0756 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K01 compound treatment 0.348 0.105 5.62 5.6206 1.0 1988254 ChemDiv2_007261 Clc1c2CCCc2nc3cc(ccc13)C(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K02 compound treatment 0.253 0.00959 0.52 0.5155 1.0 1988255 ChemDiv2_007262 CC(CCc1ccccc1)NC(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K03 compound treatment 0.26 0.0166 0.89 0.8917 1.0 1988256 ChemDiv2_007263 CCN(C(=O)c1ccc2c(SCC(=O)O)c3CCCc3nc2c1)c4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K04 compound treatment 0.305 0.0616 3.31 3.3099 1.0 1988257 ChemDiv2_007264 CC(NC(=O)Cn1nc(Cc2cccnc2)c3ccccc3c1=O)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K05 compound treatment 0.554 0.311 16.69 16.6907 1.0 1988258 ChemDiv2_007265 Nc1nnc(SCc2cc(=O)n3ccsc3n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K06 compound treatment 0.277 0.0336 1.81 1.8053 1.0 1988259 ChemDiv2_007266 CN(C)CCNC(=O)c1ccc2SCCN(Cc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K07 compound treatment 0.32 0.0766 4.12 4.116 1.0 1988260 ChemDiv2_007267 NC(=O)CSc1nc(nc2Oc3ccccc3Cc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K08 compound treatment 0.37 0.127 6.8 6.8029 1.0 1988261 ChemDiv2_007268 Fc1ccc(CN2CCSc3ccc(cc23)C(=O)NC4CC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K09 compound treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1988262 ChemDiv2_007269 Cc1nc2c3ccccc3n4c(CCCC(=O)NC5CC5)nnc4n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K10 compound treatment 0.407 0.164 8.79 8.7912 1.0 1988263 ChemDiv2_007270 Clc1ccc(CN2CCSc3ccc(cc23)C(=O)NCCN4CCOCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K11 compound treatment 0.291 0.0476 2.56 2.5576 1.0 1988264 ChemDiv2_007271 COCC(=O)Nc1c(oc2ccccc12)C(=O)Nc3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K12 compound treatment 0.255 0.0116 0.62 0.623 1.0 1988265 ChemDiv2_007272 O=C(CC1Oc2ccccc2NC1=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K13 compound treatment 0.305 0.0616 3.31 3.3099 1.0 1988266 ChemDiv2_007273 COCCn1c(=O)n(CC=C)c2c3ccccc3sc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K14 compound treatment 0.308 0.0646 3.47 3.4711 1.0 1988267 ChemDiv2_007274 COc1ccc(cc1)N2CCN(CC2)C(=O)CNC3=NS(=O)(=O)C(=C3C)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K15 compound treatment 0.306 0.0626 3.36 3.3637 1.0 1988268 ChemDiv2_007275 O=C(N(Cc1ccco1)C2CCCC2)c3cnn4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K16 compound treatment 0.282 0.0386 2.07 2.0739 1.0 1988269 ChemDiv2_007276 CCC(C)NC(=O)Cn1nc(c2ccccc2)c3cc(Cl)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K17 compound treatment 0.295 0.0516 2.77 2.7725 1.0 1988270 ChemDiv2_007277 CCOC(=O)N1CCc2c(C1)sc3n(CC(=O)N(CC)CC)c(=O)n(c4ccc(F)cc4)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K18 compound treatment 0.398 0.155 8.31 8.3075 1.0 1988271 ChemDiv2_007278 CN(C)CCN(Cc1ccco1)C(=O)c2cc3COc4cccc(C)c4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K19 compound treatment 0.502 0.259 13.9 13.8963 1.0 1988272 ChemDiv2_007279 C(CC1=CCCCC1)Nc2nnc(Cc3cccnc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K20 compound treatment 0.278 0.0346 1.86 1.859 1.0 1988273 ChemDiv2_007280 CN(CCNC(=O)c1cc2COc3ccccc3-c2s1)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K21 compound treatment 0.317 0.0736 3.95 3.9548 1.0 1988274 ChemDiv2_007281 O=C(Cn1nc(Cc2ccncc2)c3ccccc3c1=O)NCCC4=CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K22 compound treatment 0.273 0.0296 1.59 1.5903 1.0 1988275 ChemDiv2_007282 Cc1nnc2ccc(nn12)N3CCN(CC3)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K23 mock treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 K24 mock treatment 0.251 0.00759 0.41 0.4081 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L01 compound treatment 0.238 -0.00541 -0.29 -0.2905 -1.0 1988276 ChemDiv2_007283 CCOC(=O)c1c(C)c(c2ccccc2)n(CC(=O)NC3CCCC3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L02 compound treatment 0.253 0.00959 0.52 0.5155 1.0 1988277 ChemDiv2_007284 COc1ccc(NC(=O)C2(CCCCC2)NS(=O)(=O)c3cccc4cccnc34)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L03 compound treatment 0.511 0.268 14.38 14.3799 1.0 1988278 ChemDiv2_007285 Cc1ccc(Cn2c(SCC(=O)Nc3ccccc3C)nc4ncccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L04 compound treatment 0.29 0.0466 2.5 2.5039 1.0 1988279 ChemDiv2_007286 COc1ccccc1CNC(=O)CN(C)S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L05 compound treatment 0.251 0.00759 0.41 0.4081 1.0 1988280 ChemDiv2_007287 O=C(Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NC3CCCC3)Nc4nccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L06 compound treatment 0.244 5.94E-4 0.03 0.0319 1.0 1988281 ChemDiv2_007288 C1CCN(CC1)c2ccc3nncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L07 compound treatment 0.299 0.0556 2.99 2.9875 1.0 1988282 ChemDiv2_007289 CCOC(=O)Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L08 compound treatment 0.261 0.0176 0.95 0.9455 1.0 1988283 ChemDiv2_007290 O=C(CSc1ccc2nnc(c3ccccc3)n2n1)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L09 compound treatment 0.532 0.289 15.51 15.5084 1.0 1988284 ChemDiv2_007291 CCCN(CCC)C(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L10 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988285 ChemDiv2_007292 CC(C)Sc1ccc2nnc(c3cccc(F)c3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L11 compound treatment 0.306 0.0626 3.36 3.3637 1.0 1988286 ChemDiv2_007293 CCN(C(=O)Cn1ncc2COc3ccccc3-c21)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L12 compound treatment 0.259 0.0156 0.84 0.838 1.0 1988287 ChemDiv2_007294 CC(=O)Nc1ccccc1c2nc3ccc(cc3[nH]c2=O)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L13 compound treatment 0.271 0.0276 1.48 1.4828 1.0 1988288 ChemDiv2_007295 C(CNc1nc2ccccc2n3cnnc13)CN4CCc5ccccc5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L14 compound treatment 0.251 0.00759 0.41 0.4081 1.0 1988289 ChemDiv2_007296 Cc1ccc(NC(=O)CC2Oc3ccc(C)cc3NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L15 compound treatment 0.269 0.0256 1.38 1.3754 1.0 1988290 ChemDiv2_007297 CN(C)S(=O)(=O)c1ccc(Nc2nc3ccccc3n4cnnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L16 compound treatment 0.244 5.94E-4 0.03 0.0319 1.0 1200813 ChemDiv2_007298 CC(=O)N(C1CS(=O)(=O)C=C1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L17 compound treatment 0.346 0.103 5.51 5.5132 1.0 1988291 ChemDiv2_007299 O=C(Nc1cccnc1)C(Cc2ccccc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L18 compound treatment 0.252 0.00859 0.46 0.4618 1.0 1988292 ChemDiv2_007300 CN(C)CCN(Cc1ccco1)C(=O)Cn2ncc3COc4ccc(C)cc4-c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L19 compound treatment 0.277 0.0336 1.81 1.8053 1.0 1988293 ChemDiv2_007301 CCC(Cc1ccccc1)NC(=O)C(Cc2ccccc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L20 compound treatment 0.533 0.29 15.56 15.5622 1.0 1988294 ChemDiv2_007302 CCc1nnc(NC(=O)CN2C(=O)CC(C)(C)Sc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L21 compound treatment 0.257 0.0136 0.73 0.7305 1.0 1988295 ChemDiv2_007303 O=C(Cn1cccc1)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L22 compound treatment 0.435 0.192 10.3 10.2958 1.0 1988296 ChemDiv2_007304 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(CC2)c3nc4ccccc4n3Cc5ccc(F)cc5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L23 mock treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 L24 mock treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M01 compound treatment 0.479 0.236 12.66 12.6603 1.0 1988297 ChemDiv2_007305 Clc1c2CCCc2nc3cc(ccc13)C(=O)NCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M02 compound treatment 0.238 -0.00541 -0.29 -0.2905 -1.0 1988298 ChemDiv2_007306 CC1CCC(CC1)NC(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M03 compound treatment 0.242 -0.00141 -0.08 -0.0756 -1.0 1988299 ChemDiv2_007307 Cc1ccccc1NC(=O)c2ccc3c(SCC(=O)O)c4CCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M04 compound treatment 0.282 0.0386 2.07 2.0739 1.0 1988300 ChemDiv2_007308 O=C(Cn1nc(Cc2cccnc2)c3ccccc3c1=O)Nc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M05 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988301 ChemDiv2_007309 CCOC(=O)c1sc2nc(CSc3nc(C)cc(=O)[nH]3)cc(=O)n2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M06 compound treatment 0.312 0.0686 3.69 3.6861 1.0 1988302 ChemDiv2_007310 O=C(NCc1ccco1)c2ccc3SCCN(Cc4ccccc4)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M07 compound treatment 0.358 0.115 6.16 6.158 1.0 1988303 ChemDiv2_007311 COC(=O)CSc1nc(nc2Oc3c(OC)cccc3Cc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M08 compound treatment 0.281 0.0376 2.02 2.0202 1.0 1988304 ChemDiv2_007312 Fc1ccc(CN2CCSc3ccc(cc23)C(=O)N4CCC5(CC4)OCCO5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M09 compound treatment 0.382 0.139 7.45 7.4477 1.0 1988305 ChemDiv2_007313 CC(C)NC(=O)CCCc1nnc2n3nc(nc3c4ccccc4n12)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M10 compound treatment 0.244 5.94E-4 0.03 0.0319 1.0 1988306 ChemDiv2_007314 CC(C)NC(=O)CC1Oc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M11 compound treatment 0.33 0.0866 4.65 4.6534 1.0 1988307 ChemDiv2_007315 COc1cccc(NC(=O)c2oc3ccccc3c2NC(=O)c4cccs4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M12 compound treatment 0.3 0.0566 3.04 3.0412 1.0 1988308 ChemDiv2_007316 O=C(CC1Oc2ccccc2NC1=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M13 compound treatment 0.271 0.0276 1.48 1.4828 1.0 1988309 ChemDiv2_007317 CCOC(=O)N1CCC(CC1)NC(=O)c2cnn3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M14 compound treatment 0.28 0.0366 1.97 1.9665 1.0 1988310 ChemDiv2_007318 CCc1ccc(NC(=O)Cn2ncn3nc(cc3c2=O)c4ccc(OC)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M15 compound treatment 0.256 0.0126 0.68 0.6768 1.0 1988311 ChemDiv2_007319 CCOC(=O)c1cnn(CCOC(=O)C2CC2)c1NC(=O)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M16 compound treatment 0.276 0.0326 1.75 1.7515 1.0 1988312 ChemDiv2_007320 Clc1ccc2n(CC(=O)NC3CC3)nc(c4ccccc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M17 compound treatment 0.285 0.0416 2.24 2.2352 1.0 1988313 ChemDiv2_007321 CCOC(=O)N1CCc2c(C1)sc3n(CC(=O)NCC4CCCO4)c(=O)n(c5ccc(CC)cc5)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M18 compound treatment 0.537 0.294 15.78 15.7771 1.0 1988314 ChemDiv2_007322 CN(C1CCCCC1)C(=O)c2cc3COc4ccccc4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M19 compound treatment 0.269 0.0256 1.38 1.3754 1.0 1988315 ChemDiv2_007323 CCN(CC)CCCNc1nnc(Cc2cccnc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M20 compound treatment 0.531 0.288 15.45 15.4547 1.0 1988316 ChemDiv2_007324 CN(Cc1ccccc1)c2ccc3nnc(c4ccccc4)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M21 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988317 ChemDiv2_007325 COc1ccc(NC(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M22 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988318 ChemDiv2_007326 CC1CC(=O)N(CC(=O)N)c2ccccc2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M23 mock treatment 0.246 0.00259 0.14 0.1394 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 M24 mock treatment 0.247 0.00359 0.19 0.1931 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N01 compound treatment 0.233 -0.0104 -0.56 -0.5592 -1.0 1988319 ChemDiv2_007327 CCOC(=O)c1c(C)c(c2ccccc2)n(CC(=O)NCc3ccco3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N02 compound treatment 0.284 0.0406 2.18 2.1814 1.0 1988320 ChemDiv2_007328 Fc1ccc(NC(=O)C(Cc2ccccc2)NS(=O)(=O)c3cccc4cccnc34)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N03 compound treatment 0.275 0.0316 1.7 1.6978 1.0 1988321 ChemDiv2_007329 COc1ccc(Cn2c(SCC(=O)Nc3cccc(Cl)c3)nc4ncccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N04 compound treatment 0.252 0.00859 0.46 0.4618 1.0 1988322 ChemDiv2_007330 CC1CC(C)CN(C1)C(=O)CN(C)S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N05 compound treatment 0.306 0.0626 3.36 3.3637 1.0 1988323 ChemDiv2_007331 CN(Cc1ccccc1)C(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N06 compound treatment 0.259 0.0156 0.84 0.838 1.0 1988324 ChemDiv2_007332 CCOc1ccc(CCNc2ccc3nncn3n2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N07 compound treatment 0.243 -4.06E-4 -0.02 -0.0218 -1.0 1988325 ChemDiv2_007333 COc1ccccc1NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c4cccnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N08 compound treatment 0.271 0.0276 1.48 1.4828 1.0 1988326 ChemDiv2_007334 O=C(CSc1ccc2nnc(c3ccccc3)n2n1)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N09 compound treatment 0.469 0.226 12.12 12.1229 1.0 1988327 ChemDiv2_007335 CC1CCCC(C)N1CCCNC(=O)c2cc3c(=O)[nH]c4ccc(C)cc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N10 compound treatment 0.281 0.0376 2.02 2.0202 1.0 1988328 ChemDiv2_007336 CCSc1ccc2nnc(c3ccc(OC)c(OC)c3)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N11 compound treatment 0.296 0.0526 2.83 2.8263 1.0 1988329 ChemDiv2_007337 CN(C(=O)Cn1ncc2COc3ccccc3-c21)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N12 compound treatment 0.254 0.0106 0.57 0.5693 1.0 1988330 ChemDiv2_007338 CC1CCCCC1NC(=O)c2ccc3nc(c4ccccc4NC(=O)C)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N13 compound treatment 0.413 0.17 9.11 9.1136 1.0 1988331 ChemDiv2_007339 CC(CCc1ccccc1)Nc2nc3ccccc3n4cnnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N14 compound treatment 0.29 0.0466 2.5 2.5039 1.0 1988332 ChemDiv2_007340 CCN1CCN(CCCNC(=O)CC2Oc3ccc(C)cc3NC2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N15 compound treatment 0.475 0.232 12.45 12.4454 1.0 1988333 ChemDiv2_007341 C(CC1=CCCCC1)Nc2nc3ccccc3n4cnnc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N16 compound treatment 0.312 0.0686 3.69 3.6861 1.0 1988334 ChemDiv2_007342 COc1cc(OC)c(NC(=O)Cn2ncc3COc4ccc(C)cc4-c32)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N17 compound treatment 0.249 0.00559 0.3 0.3006 1.0 1988335 ChemDiv2_007343 CCC(C)NC(=O)C(Cc1ccccc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N18 compound treatment 0.291 0.0476 2.56 2.5576 1.0 1988336 ChemDiv2_007344 CCOC(=O)C1CCCN(C1)c2c(cnc3ccccc23)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N19 compound treatment 0.247 0.00359 0.19 0.1931 1.0 1988337 ChemDiv2_007345 CCOc1ccc(OCC)c(NC(=O)C(Cc2ccccc2)n3cccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N20 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988338 ChemDiv2_007346 CCCCN(C)C(=O)CN1C(=O)CC(C)(C)Sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N21 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988339 ChemDiv2_007347 O=C(Cn1cccc1)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N22 compound treatment 0.386 0.143 7.66 7.6627 1.0 1988340 ChemDiv2_007348 COc1ccc(OC)c(CCNC(=O)C2CCCN(C2)c3nc4ccccc4[nH]3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N23 mock treatment 0.244 5.94E-4 0.03 0.0319 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 N24 mock treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O01 compound treatment 0.257 0.0136 0.73 0.7305 1.0 1988341 ChemDiv2_007349 COc1ccc(CCNC(=O)c2ccc3c(Cl)c4CCCc4nc3c2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O02 compound treatment 0.259 0.0156 0.84 0.838 1.0 1988342 ChemDiv2_007350 CCc1nnc(NC(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O03 compound treatment 0.232 -0.0114 -0.61 -0.6129 -1.0 1988343 ChemDiv2_007351 Cc1cc2nc(CSc3ccccc3C(=O)O)cc(=O)n2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O04 compound treatment 0.245 0.00159 0.09 0.0856 1.0 1988344 ChemDiv2_007352 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)N3CCCC3C(=O)Nc4nccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O05 compound treatment 0.361 0.118 6.32 6.3192 1.0 1988345 ChemDiv2_007353 Cc1nn2c(=O)cc(CSc3ccc(C)cc3)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O06 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988346 ChemDiv2_007354 CCCNC(=O)c1ccc2SCCN(Cc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O07 compound treatment 0.26 0.0166 0.89 0.8917 1.0 1988347 ChemDiv2_007355 Cc1nc2c3ccccc3n4c(CCCC(=O)NCc5ccccn5)nnc4n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O08 compound treatment 0.424 0.181 9.7 9.7047 1.0 1988348 ChemDiv2_007356 CCOC(=O)C1CCCN(C1)C(=O)c2ccc3SCCN(CC)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O09 compound treatment 0.23 -0.0134 -0.72 -0.7204 -1.0 1988349 ChemDiv2_007357 CC1CCCCC1NC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O10 compound treatment 0.236 -0.00741 -0.4 -0.398 -1.0 1988350 ChemDiv2_007358 CCC(=O)N1C(CSC1c2ccc(OC)cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O11 compound treatment 0.242 -0.00141 -0.08 -0.0756 -1.0 1988351 ChemDiv2_007359 CCOCC(=O)Nc1c(oc2ccccc12)C(=O)Nc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O12 compound treatment 0.247 0.00359 0.19 0.1931 1.0 1988352 ChemDiv2_007360 COc1ccc(CCNC(=O)Cn2sc3nc(C)cc(C)c3c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O13 compound treatment 0.266 0.0226 1.21 1.2141 1.0 1988353 ChemDiv2_007361 O=C(NCc1cccnc1)c2cnn3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O14 compound treatment 0.33 0.0866 4.65 4.6534 1.0 1988354 ChemDiv2_007362 Cc1cc2n(Cc3ccc(Cl)cc3)c(cc2o1)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O15 compound treatment 0.308 0.0646 3.47 3.4711 1.0 1988355 ChemDiv2_007363 CCOC(=O)c1cnn(CCOC(=O)c2ccccc2)c1NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O16 compound treatment 0.244 5.94E-4 0.03 0.0319 1.0 1988356 ChemDiv2_007364 CCCNC(=O)C(C)n1nc(c2ccccc2)c3cc(Cl)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O17 compound treatment 0.321 0.0776 4.17 4.1697 1.0 1988357 ChemDiv2_007365 CCOC(=O)N1CCc2c(C1)sc3n(CC(=O)Nc4cccc(OC)c4)c(=O)n(Cc5ccccc5)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O18 compound treatment 0.443 0.2 10.73 10.7258 1.0 1988358 ChemDiv2_007366 CC(C)NC(=O)c1cc2COc3ccccc3-c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O19 compound treatment 0.439 0.196 10.51 10.5108 1.0 1988359 ChemDiv2_007367 COc1ccc(CCNc2nnc(Cc3cccnc3)c4ccccc24)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O20 compound treatment 0.28 0.0366 1.97 1.9665 1.0 1988360 ChemDiv2_007368 Clc1ccc(CNc2ccc3nnc(c4ccccc4)n3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O21 compound treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1988361 ChemDiv2_007369 CN(C1CCCCC1)C(=O)Cn2nc(Cc3ccncc3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O22 compound treatment 0.281 0.0376 2.02 2.0202 1.0 1988362 ChemDiv2_007370 COc1ccc(cc1)C2CC(=O)N(CC(=O)c3ccccc3)c4ccccc4S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O23 mock treatment 0.251 0.00759 0.41 0.4081 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 O24 mock treatment 0.252 0.00859 0.46 0.4618 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P01 compound treatment 0.232 -0.0114 -0.61 -0.6129 -1.0 1988363 ChemDiv2_007371 CCOC(=O)c1cc(c2ccc(C)cc2)n(CC(=O)NCc3ccccn3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P02 compound treatment 0.225 -0.0184 -0.99 -0.9891 -1.0 1988364 ChemDiv2_007372 CN(Cc1ccco1)C(=O)C(Cc2ccccc2)NS(=O)(=O)c3cccc4cccnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P03 compound treatment 0.217 -0.0264 -1.42 -1.419 -1.0 1988365 ChemDiv2_007373 CCOC(=O)c1sc(NC(=O)C(C)Sc2ncnc3ccccc23)c(C(=O)OCC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P04 compound treatment 0.216 -0.0274 -1.47 -1.4728 -1.0 1988366 ChemDiv2_007374 CC1Cc2ccccc2N1C(=O)CN(C)S(=O)(=O)c3cccc4cccnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P05 compound treatment 0.23 -0.0134 -0.72 -0.7204 -1.0 1988367 ChemDiv2_007375 O=C(Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NCc3ccccc3)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P06 compound treatment 0.239 -0.00441 -0.24 -0.2368 -1.0 1988368 ChemDiv2_007376 C(CNc1ccc2nncn2n1)CN3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P07 compound treatment 0.219 -0.0244 -1.31 -1.3115 -1.0 1988369 ChemDiv2_007377 Fc1ccc(Cn2c(=O)n(Cc3ccc(F)cc3)c4ncccc4c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P08 compound treatment 0.408 0.165 8.84 8.8449 1.0 1988370 ChemDiv2_007378 COC(=O)c1ccc(CSc2ccc3nnc(c4ccccc4)n3n2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P09 compound treatment 0.281 0.0376 2.02 2.0202 1.0 1988371 ChemDiv2_007379 CCCCN(Cc1ccco1)C(=O)c2cc3c(=O)[nH]c4ccc(C)cc4c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P10 compound treatment 0.226 -0.0174 -0.94 -0.9354 -1.0 1988372 ChemDiv2_007380 COc1ccc(cc1OC)c2nnc3ccc(SCC(=O)NCCc4ccccc4)nn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P11 compound treatment 0.22 -0.0234 -1.26 -1.2578 -1.0 1988373 ChemDiv2_007381 O=C(Cn1ncc2COc3ccccc3-c21)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P12 compound treatment 0.221 -0.0224 -1.2 -1.2041 -1.0 1988374 ChemDiv2_007382 Brc1ccccc1NC(=O)CC2Oc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P13 compound treatment 0.238 -0.00541 -0.29 -0.2905 -1.0 1988375 ChemDiv2_007383 CC1CN(CCN1c2cccc(C)c2)c3nc4ccccc4n5cnnc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P14 compound treatment 0.266 0.0226 1.21 1.2141 1.0 1988376 ChemDiv2_007384 CN(Cc1ccccc1)C(=O)CC2Oc3ccc(C)cc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P15 compound treatment 0.26 0.0166 0.89 0.8917 1.0 1988377 ChemDiv2_007385 Clc1cccc(c1)N2CCN(CCNc3nc4ccccc4n5cnnc35)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P16 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988378 ChemDiv2_007386 CN(C1CCCCC1)C(=O)Cn2ncc3COc4ccc(C)cc4-c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P17 compound treatment 0.231 -0.0124 -0.67 -0.6667 -1.0 1988379 ChemDiv2_007387 O=C(NC1CCCCC1)C(Cc2ccccc2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P18 compound treatment 0.258 0.0146 0.78 0.7842 1.0 1988380 ChemDiv2_007388 CCc1ccc(cc1)C(=O)c2cnc3cc4OCCOc4cc3c2N5CCC(CC5)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P19 compound treatment 0.231 -0.0124 -0.67 -0.6667 -1.0 1988381 ChemDiv2_007389 O=C(C(Cc1ccccc1)n2cccc2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P20 compound treatment 0.277 0.0336 1.81 1.8053 1.0 1988382 ChemDiv2_007390 CC(N1C(=O)CC(C)(C)Sc2ccccc12)C(=O)NCCc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P21 compound treatment 0.241 -0.00241 -0.13 -0.1293 -1.0 1988383 ChemDiv2_007391 Fc1ccc(CNC(=O)Cn2cccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P22 compound treatment 0.25 0.00659 0.35 0.3543 1.0 1988384 ChemDiv2_007392 CCc1ccc(NC(=O)Cn2c(cc3occc23)C(=O)OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P23 mock treatment 0.24 -0.00341 -0.18 -0.183 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1389 P24 mock treatment 0.227 -0.0164 -0.88 -0.8816 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A01 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988385 ChemDiv2_007393 COC(=O)c1cc2occc2n1CC(=O)Nc3cc(C)cc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A02 compound treatment 0.271 0.0295 1.59 1.5853 1.0 1988386 ChemDiv2_007394 COC(=O)c1ccc2N3CCCC3C(=O)N(Cc4nc(oc4C)c5ccccc5C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A03 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988387 ChemDiv2_007395 COC(=O)c1cc2ccsc2n1CC(=O)N(C)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A04 compound treatment 0.227 -0.0145 -0.78 -0.7792 -1.0 1988388 ChemDiv2_007396 COc1ccc(cc1OC)c2nc(CN3C(=O)CSc4ncccc34)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A05 compound treatment 0.248 0.0065 0.35 0.3493 1.0 1988389 ChemDiv2_007397 CCN1CCN(CC1)C(=O)C2CCN(CC2)C(=O)c3cc4sccc4n3Cc5ccc(F)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A06 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988390 ChemDiv2_007398 O=C(NC1CC1)C2CCN(CC2)C(=O)c3sccc3n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A07 compound treatment 0.295 0.0535 2.87 2.875 1.0 1988391 ChemDiv2_007399 O=C(N1CCCCC1)c2ccc(CSc3nc4cnccc4[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A08 compound treatment 0.23 -0.0115 -0.62 -0.618 -1.0 1988392 ChemDiv2_007400 OC(=O)Cn1ncn2c(cc3ccccc32)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A09 compound treatment 0.312 0.0705 3.79 3.7885 1.0 1988393 ChemDiv2_007401 CCOc1ccc2nc(sc2c1)N3CCCC(C3)C(=O)NCCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A10 compound treatment 0.317 0.0755 4.06 4.0572 1.0 1988394 ChemDiv2_007402 CCOC(=O)C1CCN(CC1)c2nc3ccccc3n2Cc4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A11 compound treatment 0.288 0.0465 2.5 2.4988 1.0 1988395 ChemDiv2_007403 Fc1ccc(cc1)S(=O)(=O)N2CCC(=CC2)C(=O)NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A12 compound treatment 0.223 -0.0185 -0.99 -0.9942 -1.0 1988396 ChemDiv2_007404 CN(C)CCNC(=O)Cn1nc(C)cc1c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A13 compound treatment 0.219 -0.0225 -1.21 -1.2091 -1.0 1988397 ChemDiv2_007405 Cc1nn(CC(=O)NC2CCCc3ccccc23)c(=O)c4cc5sccc5n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A14 compound treatment 0.222 -0.0195 -1.05 -1.0479 -1.0 1988398 ChemDiv2_007406 O=C(Cn1cnc2n(ncc2c1=O)c3ccccc3)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A15 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988399 ChemDiv2_007407 CCCCN(CC)C(=O)Cn1nc(CC)n2c3ccsc3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A16 compound treatment 0.314 0.0725 3.9 3.896 1.0 1988400 ChemDiv2_007408 COC(=O)c1ccc(Cn2cnc3n(ncc3c2=O)c4ccccc4)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A17 compound treatment 0.313 0.0715 3.84 3.8423 1.0 1988401 ChemDiv2_007409 Cc1nn(CCCC(=O)NCCC2=CCCCC2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A18 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988402 ChemDiv2_007410 Cc1ccc(cc1C)n2ncc3c(=O)n(C/C=C/c4ccccc4)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A19 compound treatment 0.605 0.363 19.53 19.5337 1.0 1988403 ChemDiv2_007411 O=C(N1CCC(=CC1)c2ccccc2)c3ccc4Sc5ccccc5C(=O)Nc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A20 compound treatment 0.268 0.0265 1.42 1.4241 1.0 1988404 ChemDiv2_007412 CS(=O)(=O)CC(=O)Nc1ccc2nc3CCCCCn3c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A21 compound treatment 0.234 -0.0075 -0.4 -0.403 -1.0 1988405 ChemDiv2_007413 CCOC(=O)N1CCC(CC1)NC(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A22 compound treatment 0.238 -0.0035 -0.19 -0.1881 -1.0 1988406 ChemDiv2_007414 COc1ccc(cc1)c2noc(n2)N(C)CC(=O)Nc3cc(Cl)c(OC)cc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A23 mock treatment 0.243 0.0015 0.08 0.0806 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 A24 mock treatment 0.247 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B01 compound treatment 0.254 0.0125 0.67 0.6717 1.0 1988407 ChemDiv2_007415 CN(C(=O)c1ccc2c(=O)n3CCCCCc3nc2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B02 compound treatment 0.255 0.0135 0.73 0.7255 1.0 1988408 ChemDiv2_007416 Cn1c2ccccc2c3cnn(CC(=O)N4CCCCC4)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B03 compound treatment 0.418 0.176 9.48 9.4847 1.0 1988409 ChemDiv2_007417 CN(CC(=O)N1CCc2ccccc2C1)S(=O)(=O)c3ccc4nc(C)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B04 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988410 ChemDiv2_007418 COC(=O)c1ccccc1NC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B05 compound treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1988411 ChemDiv2_007419 O=C(Cn1cccc1C(=O)c2ccccc2)NCCCN3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B06 compound treatment 0.276 0.0345 1.85 1.854 1.0 1988412 ChemDiv2_007420 Cc1ccc(C)c(Cn2c3ccccc3c4cnn(CC(=O)NCCCN5CCOCC5)c(=O)c24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B07 compound treatment 0.237 -0.0045 -0.24 -0.2418 -1.0 1988413 ChemDiv2_007421 CC(C(=O)NCc1cccnc1)n2cccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B08 compound treatment 0.256 0.0145 0.78 0.7792 1.0 1988414 ChemDiv2_007422 COc1cccc(CNC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5F)c3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B09 compound treatment 0.5 0.259 13.89 13.8912 1.0 1988415 ChemDiv2_007423 O=C(NC1CCCc2ccccc12)C3CCN(CC3)c4nnc(s4)n5cccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B10 compound treatment 0.308 0.0665 3.57 3.5736 1.0 1988416 ChemDiv2_007424 O=C(Cn1cc2CCCCc2n1)Nc3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B11 compound treatment 0.355 0.114 6.1 6.0993 1.0 1988417 ChemDiv2_007425 CCN1CCCC1CNC(=O)c2ccc3nc(sc3c2)N4CCC(C)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B12 compound treatment 0.289 0.0475 2.55 2.5526 1.0 1988418 ChemDiv2_007426 O=C(Cn1c2ccccc2c3cn[nH]c(=O)c13)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B13 compound treatment 0.35 0.109 5.83 5.8306 1.0 1988419 ChemDiv2_007427 CCOC(=O)N1CCC(CC1)NC(=O)C2CCN(CC2)c3ncnc4c3sc5cccc(F)c54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B14 compound treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1988420 ChemDiv2_007428 CCc1nn(CC(=O)N2CC(C)CC(C)C2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B15 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988421 ChemDiv2_007429 CNC(=O)CCCN1C(=O)CSc2ncccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B16 compound treatment 0.259 0.0175 0.94 0.9404 1.0 1988422 ChemDiv2_007430 Cc1n(CCCC(=O)N2CCc3ccccc23)c(C)c4c(=O)n(ncc14)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B17 compound treatment 0.52 0.279 14.97 14.966 1.0 1988423 ChemDiv2_007431 O=C(CC(=O)Nc1ccc2nc3CCCCCn3c(=O)c2c1)NC4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B18 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988424 ChemDiv2_007432 CCN1CCCC1CNC(=O)CCCn2c(C)c3cnn(c4ccccc4)c(=O)c3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B19 compound treatment 0.282 0.0405 2.18 2.1764 1.0 1988425 ChemDiv2_007433 Cc1cccc(CSc2nc3ccncc3n2CC(=O)NCc4ccco4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B20 compound treatment 0.285 0.0435 2.34 2.3376 1.0 1988426 ChemDiv2_007434 CCCCN(CC)C(=O)Cn1ncc2c(C)n(Cc3ccc(F)cc3)c(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B21 compound treatment 0.341 0.0995 5.35 5.3469 1.0 1988427 ChemDiv2_007435 COc1ccc(CC(=O)Cn2c(SCc3ccc(F)cc3)nc4ccncc24)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B22 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988428 ChemDiv2_007436 CCN(C(=O)c1cc2CS(=O)(=O)c3ccccc3-c2s1)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B23 mock treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 B24 mock treatment 0.233 -0.0085 -0.46 -0.4568 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C01 compound treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1988429 ChemDiv2_007437 COC(=O)c1cc2occc2n1CC(=O)Nc3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C02 compound treatment 0.322 0.0805 4.33 4.3259 1.0 1988430 ChemDiv2_007438 COc1ccccc1CNC(=O)c2ccc3n(C)c(=O)c(=O)n(C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C03 compound treatment 0.279 0.0375 2.02 2.0152 1.0 1988431 ChemDiv2_007439 COC(=O)c1cc2ccsc2n1CC(=O)Nc3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C04 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988432 ChemDiv2_007440 O=C(Cn1cccc1C(=O)c2ccccc2)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C05 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988433 ChemDiv2_007441 Fc1ccc(Cn2c(cc3sccc23)C(=O)N4CCC(CC4)C(=O)NCCN5CCOCC5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C06 compound treatment 0.51 0.269 14.43 14.4286 1.0 1988434 ChemDiv2_007442 Cc1c(oc2ccc3OC(C)(C)CC(=O)c3c12)C(=O)NCc4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C07 compound treatment 0.533 0.291 15.66 15.6646 1.0 1988435 ChemDiv2_007443 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C08 compound treatment 0.5 0.259 13.89 13.8912 1.0 1988436 ChemDiv2_007444 Brc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)N4CCC5(CC4)OCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C09 compound treatment 0.281 0.0395 2.12 2.1226 1.0 1988437 ChemDiv2_007445 Cc1cc(C)c2nc(sc2c1)N3CCC(CC3)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C10 compound treatment 0.27 0.0285 1.53 1.5315 1.0 1988438 ChemDiv2_007446 CCN1CCN(CCCNC(=O)C2CCN(CC2)c3nc4ccccc4n3Cc5ccc(F)cc5)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C11 compound treatment 0.457 0.216 11.58 11.5805 1.0 1988439 ChemDiv2_007447 CCOc1ccc(CCNC(=O)C2=CCN(CC2)S(=O)(=O)c3ccc(F)cc3)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C12 compound treatment 0.23 -0.0115 -0.62 -0.618 -1.0 1988440 ChemDiv2_007448 CCC(C)NC(=O)Cn1nc(C)cc1c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C13 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988441 ChemDiv2_007449 CC1CCC(CC1)NC(=O)Cn2nc(C)n3c4ccsc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C14 compound treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1988442 ChemDiv2_007450 NC(=O)Cn1cnc2n(ncc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C15 compound treatment 0.524 0.282 15.18 15.181 1.0 1988443 ChemDiv2_007451 CCN(CC)C(=O)CCCn1nc(C)n2c3ccsc3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C16 compound treatment 0.248 0.0065 0.35 0.3493 1.0 1988444 ChemDiv2_007452 COC(=O)Cn1cnc2n(ncc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C17 compound treatment 0.277 0.0355 1.91 1.9077 1.0 1988445 ChemDiv2_007453 CCc1cccc(NC(=O)Cn2ncn3c(cc4ccccc43)c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C18 compound treatment 0.247 0.0055 0.3 0.2956 1.0 1988446 ChemDiv2_007454 Cc1ccc(cc1C)n2ncc3c(=O)n(Cc4c(F)cccc4Cl)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C19 compound treatment 0.259 0.0175 0.94 0.9404 1.0 1988447 ChemDiv2_007455 Clc1cccc(CNC(=O)Cn2ncc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C20 compound treatment 0.25 0.0085 0.46 0.4568 1.0 1988448 ChemDiv2_007456 O=C(Cn1c(=O)oc2ccccc12)Nc3ccc4nc5CCCCCn5c(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C21 compound treatment 0.261 0.0195 1.05 1.0479 1.0 1988449 ChemDiv2_007457 Clc1ccc(NC(=O)Cn2ncc3ccccc23)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C22 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1988450 ChemDiv2_007458 O=C(N1CCCCCC1)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C23 mock treatment 0.247 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 C24 mock treatment 0.252 0.0105 0.56 0.5642 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D01 compound treatment 0.247 0.0055 0.3 0.2956 1.0 1988451 ChemDiv2_007459 COC(=O)c1cc(NC(=O)c2ccc3c(=O)n4CCCCCc4nc3c2)cc(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D02 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988452 ChemDiv2_007460 CNC(=O)Cn1ncc2c3ccccc3n(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D03 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988453 ChemDiv2_007461 CN(CC(=O)NC1CCN(Cc2ccccc2)CC1)S(=O)(=O)c3ccc4nc(C)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D04 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988454 ChemDiv2_007462 CC(C)NC(=O)Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D05 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1988455 ChemDiv2_007463 O=C(Cn1cccc1C(=O)c2ccccc2)NCCCN3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D06 compound treatment 0.264 0.0225 1.21 1.2091 1.0 1988456 ChemDiv2_007464 CCN1CCCC1CNC(=O)Cn2ncc3c4ccccc4n(Cc5cc(C)ccc5C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D07 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988457 ChemDiv2_007465 CC(C(=O)NCC1CCCO1)n2cccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D08 compound treatment 0.267 0.0255 1.37 1.3703 1.0 1988458 ChemDiv2_007466 Fc1ccccc1Cn2c3ccccc3c4cnn(CC(=O)NCc5cccs5)c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D09 compound treatment 0.561 0.32 17.17 17.1693 1.0 1988459 ChemDiv2_007467 CC1CCN(Cc2ccc(NC(=O)C3CCN(CC3)c4nnc(s4)n5cccc5)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D10 compound treatment 0.251 0.0095 0.51 0.5105 1.0 1988460 ChemDiv2_007468 Cc1ccc(NC(=O)Cn2cc3CCCCc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D11 compound treatment 0.486 0.245 13.14 13.1389 1.0 1988461 ChemDiv2_007469 CNC(=O)c1ccc2nc(sc2c1)N3CCC(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D12 compound treatment 0.27 0.0285 1.53 1.5315 1.0 1988462 ChemDiv2_007470 CCCNC(=O)Cn1c2ccccc2c3cn[nH]c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D13 compound treatment 0.331 0.0895 4.81 4.8095 1.0 1988463 ChemDiv2_007471 COC(=O)c1ccccc1NC(=O)C2CCN(CC2)c3ncnc4c3sc5cccc(F)c54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D14 compound treatment 0.227 -0.0145 -0.78 -0.7792 -1.0 1988464 ChemDiv2_007472 CCc1nn(CC(=O)NC)c(=O)c2cc3occc3n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D15 compound treatment 0.236 -0.0055 -0.3 -0.2956 -1.0 1988465 ChemDiv2_007473 CN1CCN(CC1)C(=O)CN2C(=O)CSc3nc(C)cc(C)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D16 compound treatment 0.286 0.0445 2.39 2.3913 1.0 1988466 ChemDiv2_007474 Cc1n(CCCC(=O)N2CCCC2)c(C)c3c(=O)n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D17 compound treatment 0.534 0.292 15.72 15.7183 1.0 1988467 ChemDiv2_007475 CCc1ccc(NC(=O)CC(=O)Nc2ccc3nc4CCCCCn4c(=O)c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D18 compound treatment 0.334 0.0925 4.97 4.9708 1.0 1988468 ChemDiv2_007476 Cc1n(CCCC(=O)NCCC2=CCCCC2)c(C)c3c(=O)n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D19 compound treatment 0.273 0.0315 1.69 1.6927 1.0 1988469 ChemDiv2_007477 Fc1cccc(CSc2nc3ccncc3n2CC(=O)N4CCCCCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D20 compound treatment 0.533 0.291 15.66 15.6646 1.0 1988470 ChemDiv2_007478 Cc1n(Cc2ccc(F)cc2)c(C)c3c(=O)n(CC(=O)NCCCN4CCCC4=O)ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D21 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988471 ChemDiv2_007479 CN(C1CCCCC1)C(=O)Cn2c(SCc3ccccc3F)nc4ccncc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D22 compound treatment 0.47 0.229 12.28 12.2791 1.0 1988472 ChemDiv2_007480 CCOc1ccc(CCNC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D23 mock treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 D24 mock treatment 0.238 -0.0035 -0.19 -0.1881 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E01 compound treatment 0.23 -0.0115 -0.62 -0.618 -1.0 1988473 ChemDiv2_007481 COC(=O)c1cc2occc2n1CC(=O)N(CC=C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E02 compound treatment 0.339 0.0975 5.24 5.2394 1.0 1988474 ChemDiv2_007482 O=C(NC1CC1)c2cc3CS(=O)(=O)Cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E03 compound treatment 0.283 0.0415 2.23 2.2301 1.0 1988475 ChemDiv2_007483 COC(=O)c1cc2ccsc2n1CC(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E04 compound treatment 0.232 -0.0095 -0.51 -0.5105 -1.0 1988476 ChemDiv2_007484 O=C(Cn1cccc1C(=O)c2ccccc2)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E05 compound treatment 0.435 0.194 10.4 10.3983 1.0 1988477 ChemDiv2_007485 O=C(NC1CCCC1)c2ccc(CSc3nc4cnccc4[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E06 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988478 ChemDiv2_007486 Cc1nn(CC(=O)NCCc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E07 compound treatment 0.564 0.323 17.33 17.3305 1.0 1988479 ChemDiv2_007487 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)Nc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E08 compound treatment 0.411 0.17 9.11 9.1086 1.0 1988480 ChemDiv2_007488 Brc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E09 compound treatment 0.308 0.0665 3.57 3.5736 1.0 1988481 ChemDiv2_007489 Cc1cc(C)c2nc(sc2c1)N3CCC(CC3)C(=O)N4CCN(CC4)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E10 compound treatment 0.273 0.0315 1.69 1.6927 1.0 1988482 ChemDiv2_007490 O=C(Oc1ccccc1)C2CCN(CC2)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E11 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988483 ChemDiv2_007491 Cc1cc2c(cc3c(=O)n(CC(=O)NCc4ccccc4)ncn23)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E12 compound treatment 0.278 0.0365 1.96 1.9614 1.0 1988484 ChemDiv2_007492 COC(=O)CC1Oc2ccc(C)cc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E13 compound treatment 0.261 0.0195 1.05 1.0479 1.0 1988485 ChemDiv2_007493 CC(CCc1ccccc1)NC(=O)Cn2nc(C)n3c4ccsc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E14 compound treatment 0.258 0.0165 0.89 0.8867 1.0 1988486 ChemDiv2_007494 O=C(Cn1cnc2n(ncc2c1=O)c3ccccc3)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E15 compound treatment 0.386 0.144 7.77 7.7651 1.0 1988487 ChemDiv2_007495 Cc1nn(CCCC(=O)N2CCCCC2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E16 compound treatment 0.266 0.0245 1.32 1.3166 1.0 1988488 ChemDiv2_007496 COC(=O)C(C)n1cnc2n(ncc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E17 compound treatment 0.385 0.143 7.71 7.7114 1.0 1988489 ChemDiv2_007497 CCOC(=O)c1ccc(NC(=O)Cn2c(cc3sccc23)C(=O)OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E18 compound treatment 0.271 0.0295 1.59 1.5853 1.0 1988490 ChemDiv2_007498 Clc1ccc(CC(=O)Nc2ccc3nc4CCCCn4c(=O)c3c2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E19 compound treatment 0.258 0.0165 0.89 0.8867 1.0 1988491 ChemDiv2_007499 CCCOc1ccc(CNC(=O)Cn2ncc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E20 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988492 ChemDiv2_007500 CN(CC(=O)NC1CCCC1)S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E21 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1988493 ChemDiv2_007501 Brc1ccccc1NC(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E22 compound treatment 0.274 0.0325 1.75 1.7465 1.0 1988494 ChemDiv2_007502 CC1CCCCN1C(=O)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E23 mock treatment 0.249 0.0075 0.4 0.403 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 E24 mock treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F01 compound treatment 0.237 -0.0045 -0.24 -0.2418 -1.0 1988495 ChemDiv2_007503 O=C(N(CCC#N)c1ccccc1)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F02 compound treatment 0.258 0.0165 0.89 0.8867 1.0 1988496 ChemDiv2_007504 Cn1c2ccccc2c3cnn(CC(=O)NCCCN4CCN(CC4)C5CCCCC5)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F03 compound treatment 0.512 0.271 14.54 14.5361 1.0 1988497 ChemDiv2_007505 CCOc1ccc(OCC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3nc(C)sc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F04 compound treatment 0.281 0.0395 2.12 2.1226 1.0 1988498 ChemDiv2_007506 CCOC(=O)c1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5)c3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F05 compound treatment 0.265 0.0235 1.26 1.2628 1.0 1988499 ChemDiv2_007507 Cc1cccc(N2CCN(CCNC(=O)Cn3cccc3C(=O)c4ccccc4)CC2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F06 compound treatment 0.265 0.0235 1.26 1.2628 1.0 1988500 ChemDiv2_007508 CCCN1CCN(CC1)C(=O)Cn2ncc3c4ccccc4n(Cc5c(C)cc(C)cc5C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F07 compound treatment 0.256 0.0145 0.78 0.7792 1.0 1988501 ChemDiv2_007509 CC(C(=O)NCc1ccc(F)cc1)n2cccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F08 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988502 ChemDiv2_007510 CN1CCN(CCCNC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5F)c3c2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F09 compound treatment 0.506 0.265 14.21 14.2137 1.0 1988503 ChemDiv2_007511 O=C(C1CCN(CC1)c2nnc(s2)n3cccc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F10 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988504 ChemDiv2_007512 CCC(C)NC(=O)Cn1cc2CC(C)CCc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F11 compound treatment 0.256 0.0145 0.78 0.7792 1.0 1988505 ChemDiv2_007513 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc3nc(sc3c2)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F12 compound treatment 0.474 0.233 12.49 12.4941 1.0 1988506 ChemDiv2_007514 CC(C)NC(=O)C1CCN(CC1)c2nn3c(=O)cc(C)nc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F13 compound treatment 0.47 0.229 12.28 12.2791 1.0 1988507 ChemDiv2_007515 Fc1cccc2sc3c(ncnc3c12)N4CCC(CC4)C(=O)NCCc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F14 compound treatment 0.233 -0.0085 -0.46 -0.4568 -1.0 1988508 ChemDiv2_007516 CCc1nn(CC(=O)NCCCN2CCC(Cc3ccccc3)CC2)c(=O)c4cc5occc5n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F15 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988509 ChemDiv2_007517 CCOC(=O)N1CCC(CC1)NC(=O)CN2C(=O)CSc3nc(C)cc(C)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F16 compound treatment 0.29 0.0485 2.61 2.6063 1.0 1988510 ChemDiv2_007518 Cc1n(CCCC(=O)N2CCc3ccccc3C2)c(C)c4c(=O)n(ncc14)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F17 compound treatment 0.25 0.0085 0.46 0.4568 1.0 1988511 ChemDiv2_007519 COc1ccc(cc1)N2C(c3c(C2=O)n(C)c4ccccc34)c5ccc(NC(=O)C)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F18 compound treatment 0.27 0.0285 1.53 1.5315 1.0 1988512 ChemDiv2_007520 Cc1n(Cc2ccc(C)cc2)c(C)c3c(=O)n(CC(=O)N4CCCCCC4)ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F19 compound treatment 0.276 0.0345 1.85 1.854 1.0 1988513 ChemDiv2_007521 CC(C)CCNC(=O)Cn1c(SCc2cccc(F)c2)nc3ccncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F20 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988514 ChemDiv2_007522 CC1CCC(CC1)NC(=O)Cn2ncc3c(C)n(Cc4ccc(F)cc4)c(C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F21 compound treatment 0.271 0.0295 1.59 1.5853 1.0 1988515 ChemDiv2_007523 COc1ccc(NC(=O)Cn2c(SCc3ccccc3F)nc4ccncc24)c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F22 compound treatment 0.272 0.0305 1.64 1.639 1.0 1988516 ChemDiv2_007524 CC(C)CCNC(=O)c1cc2CS(=O)(=O)c3ccccc3-c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F23 mock treatment 0.23 -0.0115 -0.62 -0.618 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 F24 mock treatment 0.236 -0.0055 -0.3 -0.2956 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G01 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988517 ChemDiv2_007525 COC(=O)c1cc2occc2n1CC(=O)Nc3ccc(F)cc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G02 compound treatment 0.285 0.0435 2.34 2.3376 1.0 1988518 ChemDiv2_007526 CN1CCN(CC1)c2nnc(NC(=O)Cn3c(=O)oc4ccccc34)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G03 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988519 ChemDiv2_007527 CCc1ccccc1NC(=O)Cn2c(cc3ccsc23)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G04 compound treatment 0.255 0.0135 0.73 0.7255 1.0 1988520 ChemDiv2_007528 Cc1nc(sc1C(=O)NC2CCCC2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G05 compound treatment 0.496 0.255 13.68 13.6763 1.0 1988521 ChemDiv2_007529 O=C(NCCCc1ccccc1)c2ccc(CSc3nc4cnccc4[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G06 compound treatment 0.228 -0.0135 -0.73 -0.7255 -1.0 1988522 ChemDiv2_007530 CC(C(=O)N1CCCCC1)n2ncn3cccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G07 compound treatment 0.484 0.242 13.03 13.0314 1.0 1988523 ChemDiv2_007531 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G08 compound treatment 0.352 0.111 5.94 5.938 1.0 1988524 ChemDiv2_007532 COC(=O)c1ccc(CSc2nc3ccncc3n2CC(=O)N4CCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G09 compound treatment 0.302 0.0605 3.25 3.2511 1.0 1988525 ChemDiv2_007533 Cc1cc(C)c2nc(sc2c1)N3CCC(CC3)C(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G10 compound treatment 0.36 0.118 6.37 6.3679 1.0 1988526 ChemDiv2_007534 CCOc1ccc(CNC(=O)C2CCN(CC2)c3nc4ccccc4[nH]3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G11 compound treatment 0.259 0.0175 0.94 0.9404 1.0 1988527 ChemDiv2_007535 O=C(Cn1ncn2c3ccsc3cc2c1=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G12 compound treatment 0.376 0.135 7.23 7.2277 1.0 1988528 ChemDiv2_007536 COC(=O)CC1Oc2ccccc2N(Cc3ccccc3)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G13 compound treatment 0.253 0.0115 0.62 0.618 1.0 1988529 ChemDiv2_007537 Cc1ccc(Cl)cc1N2CCN(CCNC(=O)Cn3nc(C)n4c5ccsc5cc4c3=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G14 compound treatment 0.248 0.0065 0.35 0.3493 1.0 1988530 ChemDiv2_007538 O=C(Cn1cnc2n(ncc2c1=O)c3ccccc3)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G15 compound treatment 0.378 0.137 7.34 7.3352 1.0 1988531 ChemDiv2_007539 Cc1nn(CCCC(=O)NCc2ccccn2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G16 compound treatment 0.316 0.0745 4.0 4.0035 1.0 1988532 ChemDiv2_007540 CCn1cnc2n(ncc2c1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G17 compound treatment 0.561 0.32 17.17 17.1693 1.0 1988533 ChemDiv2_007541 Cc1cc(NC(=O)c2ccc3Sc4ccccc4C(=O)Nc3c2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G18 compound treatment 0.432 0.191 10.24 10.2371 1.0 1988534 ChemDiv2_007542 Cc1ccccc1C(=O)Nc2ccc3nc4CCCn4c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G19 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988535 ChemDiv2_007543 CN1CCN(CC1)C(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G20 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988536 ChemDiv2_007544 CC1CCCC(NC(=O)CN(C)S(=O)(=O)c2c[nH]cn2)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G21 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988537 ChemDiv2_007545 CC1CCC(CC1)NC(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G22 compound treatment 0.287 0.0455 2.45 2.4451 1.0 1988538 ChemDiv2_007546 CC1CCCC(NC(=O)c2ccc3c(=O)n4CCCCCc4nc3c2)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G23 mock treatment 0.243 0.0015 0.08 0.0806 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 G24 mock treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H01 compound treatment 0.303 0.0615 3.3 3.3049 1.0 1988539 ChemDiv2_007547 CN(CCC#N)C(=O)c1ccc2c(=O)n3CCCCCc3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H02 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988540 ChemDiv2_007548 Cc1cccc(N2CCN(CCNC(=O)Cn3ncc4c5ccccc5n(C)c4c3=O)CC2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H03 compound treatment 0.268 0.0265 1.42 1.4241 1.0 1988541 ChemDiv2_007549 CCOC(=O)N1CCC(CC1)NC(=O)Cn2cccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H04 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988542 ChemDiv2_007550 O=C(Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O)NCCc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H05 compound treatment 0.253 0.0115 0.62 0.618 1.0 1988543 ChemDiv2_007551 Cc1ccccc1C(=O)c2cccn2CC(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H06 compound treatment 0.258 0.0165 0.89 0.8867 1.0 1988544 ChemDiv2_007552 Cc1cc(C)c(Cn2c3ccccc3c4cnn(CC(=O)NCc5ccco5)c(=O)c24)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H07 compound treatment 0.505 0.264 14.16 14.1599 1.0 1988545 ChemDiv2_007553 O=C(NCc1ccc2OCOc2c1)C3CCN(CC3)c4nnc(s4)n5cccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H08 compound treatment 0.269 0.0275 1.48 1.4778 1.0 1988546 ChemDiv2_007554 Clc1ccc(Cn2c3ccccc3c4cnn(CC(=O)NC5CC5)c(=O)c24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H09 compound treatment 0.538 0.296 15.93 15.9333 1.0 1988547 ChemDiv2_007555 COc1cc(OC)c(NC(=O)C2CCCN(C2)c3nnc(s3)n4cccc4)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H10 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988548 ChemDiv2_007556 CC1CCc2nn(CC(=O)NC3CCCCCC3)cc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H11 compound treatment 0.331 0.0895 4.81 4.8095 1.0 1988549 ChemDiv2_007557 O=C(NCc1ccccc1)c2ccc3nc(sc3c2)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H12 compound treatment 0.309 0.0675 3.63 3.6273 1.0 1988550 ChemDiv2_007558 CCN(Cc1ccccc1)C(=O)Cn2nc(C)n3c4ccoc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H13 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988551 ChemDiv2_007559 COc1cc(OC)c(NC(=O)CN2C(=O)CSc3ncccc23)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H14 compound treatment 0.25 0.0085 0.46 0.4568 1.0 1988552 ChemDiv2_007560 CC(C(=O)NCc1ccccc1)n2nc(C)n3c4ccoc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H15 compound treatment 0.238 -0.0035 -0.19 -0.1881 -1.0 1988553 ChemDiv2_007561 CNC(=O)CN1C(=O)CSc2nc(C)cc(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H16 compound treatment 0.293 0.0515 2.77 2.7675 1.0 1988554 ChemDiv2_007562 Cc1n(CCCC(=O)Nc2c(C)cccc2C)c(C)c3c(=O)n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H17 compound treatment 0.264 0.0225 1.21 1.2091 1.0 1988555 ChemDiv2_007563 CC(C)CC(=O)N1CCC(CC1)(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H18 compound treatment 0.271 0.0295 1.59 1.5853 1.0 1988556 ChemDiv2_007564 Cc1n(Cc2ccc(C)cc2)c(C)c3c(=O)n(CC(=O)NCC4CCCO4)ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H19 compound treatment 0.27 0.0285 1.53 1.5315 1.0 1988557 ChemDiv2_007565 Fc1cccc(CSc2nc3ccncc3n2CC(=O)NCC4CCCO4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H20 compound treatment 0.286 0.0445 2.39 2.3913 1.0 1988558 ChemDiv2_007566 Clc1cccc(NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H21 compound treatment 0.379 0.138 7.39 7.389 1.0 1988559 ChemDiv2_007567 Clc1cccc(CSc2nc3ccncc3n2Cc4ccccn4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H22 compound treatment 0.283 0.0415 2.23 2.2301 1.0 1988560 ChemDiv2_007568 Cc1csc(NC(=O)CCc2c(C)nc3n(nc(C)c3c2C)c4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H23 mock treatment 0.243 0.0015 0.08 0.0806 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 H24 mock treatment 0.248 0.0065 0.35 0.3493 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I01 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988561 ChemDiv2_007569 COC(=O)c1cc2oc(C)cc2n1CC(=O)NCCC3=CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I02 compound treatment 0.286 0.0445 2.39 2.3913 1.0 1988562 ChemDiv2_007570 CN(Cc1ccccc1)c2nnc(NC(=O)Cn3c(=O)oc4ccccc34)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I03 compound treatment 0.269 0.0275 1.48 1.4778 1.0 1988563 ChemDiv2_007571 COC(=O)c1cc2ccsc2n1CC(=O)Nc3ccc(C)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I04 compound treatment 0.472 0.231 12.39 12.3866 1.0 1988564 ChemDiv2_007572 Fc1cccc2sc3c(ncnc3c12)N4CCC(CC4)C(=O)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I05 compound treatment 0.474 0.233 12.49 12.4941 1.0 1988565 ChemDiv2_007573 O=C(NCc1ccc2OCOc2c1)c3ccc(CSc4nc5cnccc5[nH]4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I06 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988566 ChemDiv2_007574 CC(C(=O)N1CCCCC1)n2sc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I07 compound treatment 0.537 0.295 15.88 15.8796 1.0 1988567 ChemDiv2_007575 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I08 compound treatment 0.315 0.0735 3.95 3.9497 1.0 1988568 ChemDiv2_007576 Cc1ccc(Cn2ncn3c(cc4ccccc43)c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I09 compound treatment 0.269 0.0275 1.48 1.4778 1.0 1988569 ChemDiv2_007577 CNC(=O)C1CCN(CC1)c2nc3c(C)cc(C)cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I10 compound treatment 0.253 0.0115 0.62 0.618 1.0 1988570 ChemDiv2_007578 OC(=O)C1CCN(CC1)c2nc3ccccc3n2Cc4cccc(F)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I11 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988571 ChemDiv2_007579 O=C(Cn1ncn2c3ccsc3cc2c1=O)NC4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I12 compound treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1988572 ChemDiv2_007580 COC(=O)CN1C(=O)CCSc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I13 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988573 ChemDiv2_007581 CCc1nn(CC(=O)Nc2cc(Cl)c(OC)cc2OC)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I14 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988574 ChemDiv2_007582 O=C(Cn1cnc2n(ncc2c1=O)c3ccccc3)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I15 compound treatment 0.333 0.0915 4.92 4.917 1.0 1988575 ChemDiv2_007583 Cc1nn(CCCC(=O)NC2CC2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I16 compound treatment 0.288 0.0465 2.5 2.4988 1.0 1988576 ChemDiv2_007584 CCCCn1cnc2n(ncc2c1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I17 compound treatment 0.307 0.0655 3.52 3.5198 1.0 1988577 ChemDiv2_007585 CC1CCCC(C)N1c2nnc(NC(=O)c3c(C)onc3c4ccccc4)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I18 compound treatment 0.523 0.281 15.13 15.1272 1.0 1988578 ChemDiv2_007586 O=C(Nc1ccc2nc3CCCCCn3c(=O)c2c1)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I19 compound treatment 0.25 0.0085 0.46 0.4568 1.0 1988579 ChemDiv2_007587 O=C(Cn1ncc2ccccc12)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I20 compound treatment 0.248 0.0065 0.35 0.3493 1.0 1988580 ChemDiv2_007588 CN(CC(=O)NCc1ccccc1)S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I21 compound treatment 0.26 0.0185 0.99 0.9942 1.0 1988581 ChemDiv2_007589 COc1ccc(Cl)cc1NC(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I22 compound treatment 0.417 0.175 9.43 9.431 1.0 1988582 ChemDiv2_007590 O=C(NCC1CCCO1)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I23 mock treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 I24 mock treatment 0.246 0.0045 0.24 0.2418 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J01 compound treatment 0.529 0.287 15.45 15.4496 1.0 1988583 ChemDiv2_007591 CSc1ccc(CCNC(=O)c2ccc3c(=O)n4CCCCCc4nc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J02 compound treatment 0.267 0.0255 1.37 1.3703 1.0 1988584 ChemDiv2_007592 CCN(CC)C(=O)Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J03 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988585 ChemDiv2_007593 O=C(Cn1cccc1C(=O)c2ccccc2)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J04 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988586 ChemDiv2_007594 Cc1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5)c3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J05 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988587 ChemDiv2_007595 Cc1ccccc1C(=O)c2cccn2CC(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J06 compound treatment 0.247 0.0055 0.3 0.2956 1.0 1988588 ChemDiv2_007596 COc1ccccc1CNC(=O)Cn2ncc3c4ccccc4n(Cc5ccc(F)cc5)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J07 compound treatment 0.519 0.278 14.91 14.9123 1.0 1988589 ChemDiv2_007597 Fc1cc(Br)ccc1NC(=O)C2CCN(CC2)c3nnc(s3)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J08 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988590 ChemDiv2_007598 Clc1ccc(NC(=O)Cn2cc3CCCCc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J09 compound treatment 0.593 0.351 18.89 18.8889 1.0 1988591 ChemDiv2_007599 COC(=O)c1ccccc1NC(=O)C2CCCN(C2)c3nnc(s3)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J10 compound treatment 0.25 0.0085 0.46 0.4568 1.0 1988592 ChemDiv2_007600 O=C(Cn1cc2CCCCCc2n1)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J11 compound treatment 0.468 0.227 12.17 12.1716 1.0 1988593 ChemDiv2_007601 COc1ccc(CCNC(=O)c2ccc3nc(sc3c2)N4CCOCC4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J12 compound treatment 0.236 -0.0055 -0.3 -0.2956 -1.0 1988594 ChemDiv2_007602 Cc1nn(CC(=O)NC2CCCCCC2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J13 compound treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1988595 ChemDiv2_007603 O=C(CN1C(=O)CSc2ncccc12)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J14 compound treatment 0.248 0.0065 0.35 0.3493 1.0 1988596 ChemDiv2_007604 CCc1nn(C(C)C(=O)NCCc2ccccc2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J15 compound treatment 0.272 0.0305 1.64 1.639 1.0 1988597 ChemDiv2_007605 Cc1cc(C)c2N(CCCC(=O)NCc3cccc(Br)c3)C(=O)CSc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J16 compound treatment 0.296 0.0545 2.93 2.9287 1.0 1988598 ChemDiv2_007606 CC(C)NC(=O)CCCn1c(C)c2cnn(c3ccccc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J17 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988599 ChemDiv2_007607 CCn1c(=O)c2sccc2n3c(=S)sc(c4ccccc4)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J18 compound treatment 0.445 0.203 10.94 10.9357 1.0 1988600 ChemDiv2_007608 CNC(=O)Cn1ncc2c(C)n(Cc3ccc(C)cc3)c(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J19 compound treatment 0.261 0.0195 1.05 1.0479 1.0 1988601 ChemDiv2_007609 Fc1cccc(CSc2nc3ccncc3n2CC(=O)NCCC4=CCCCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J20 compound treatment 0.27 0.0285 1.53 1.5315 1.0 1988602 ChemDiv2_007610 Cc1cc(NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J21 compound treatment 0.493 0.252 13.52 13.5151 1.0 1988603 ChemDiv2_007611 Fc1ccc(Cn2c(SCc3ccc(cc3)C(=O)N4CCCC4)nc5ccncc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J22 compound treatment 0.25 0.0085 0.46 0.4568 1.0 1988604 ChemDiv2_007612 Cc1nn(c2ccccc2)c3nc(C)c(CCC(=O)N4CCc5ccccc45)c(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J23 mock treatment 0.247 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 J24 mock treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K01 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988605 ChemDiv2_007613 CCC(C(=O)Nc1ccccc1OC)n2c(cc3oc(C)cc23)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K02 compound treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1988606 ChemDiv2_007614 CC(C)CN(CC(C)C)c1nnc(NC(=O)Cn2c(=O)oc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K03 compound treatment 0.238 -0.0035 -0.19 -0.1881 -1.0 1988607 ChemDiv2_007615 CCC(C(=O)Nc1ccccc1OC)n2c(cc3ccsc23)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K04 compound treatment 0.234 -0.0075 -0.4 -0.403 -1.0 1988608 ChemDiv2_007616 O=C(NCc1ccccc1)C2CCN(CC2)C(=O)c3sccc3n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K05 compound treatment 0.349 0.108 5.78 5.7768 1.0 1988609 ChemDiv2_007617 COc1ccccc1CNC(=O)c2ccc(CSc3nc4cnccc4[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K06 compound treatment 0.226 -0.0155 -0.83 -0.8329 -1.0 1988610 ChemDiv2_007618 O=C(Cn1ncn2cccc2c1=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K07 compound treatment 0.551 0.31 16.63 16.6319 1.0 1988611 ChemDiv2_007619 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NCCc4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K08 compound treatment 0.455 0.214 11.47 11.473 1.0 1988612 ChemDiv2_007620 COC(=O)C(C)n1c(SCc2ccc(cc2)C(=O)OC)nc3ccncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K09 compound treatment 0.258 0.0165 0.89 0.8867 1.0 1988613 ChemDiv2_007621 Cc1cc(C)c2nc(sc2c1)N3CCC(CC3)C(=O)NCCCN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K10 compound treatment 0.286 0.0445 2.39 2.3913 1.0 1988614 ChemDiv2_007622 COc1cccc(CSc2nc3ccncc3[nH]2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K11 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988615 ChemDiv2_007623 Cc1ccc(CCNC(=O)Cn2ncn3c4ccsc4cc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K12 compound treatment 0.473 0.232 12.44 12.4403 1.0 1988616 ChemDiv2_007624 CCOC(=O)c1cc(C)n(Cc2ccccc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K13 compound treatment 0.261 0.0195 1.05 1.0479 1.0 1988617 ChemDiv2_007625 CCc1nn(CC(=O)NCCc2ccccc2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K14 compound treatment 0.237 -0.0045 -0.24 -0.2418 -1.0 1988618 ChemDiv2_007626 COc1ccc(CCNC(=O)Cn2cnc3n(ncc3c2=O)c4ccccc4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K15 compound treatment 0.301 0.0595 3.2 3.1974 1.0 1988619 ChemDiv2_007627 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K16 compound treatment 0.279 0.0375 2.02 2.0152 1.0 1988620 ChemDiv2_007628 Clc1ccc(cc1)n2ncc3c(=O)n(CC=C)cnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K17 compound treatment 0.644 0.403 21.63 21.6295 1.0 1988621 ChemDiv2_007629 CCN(Cc1ccccc1)C(=O)c2ccc3Sc4ccccc4C(=O)Nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K18 compound treatment 0.552 0.311 16.69 16.6856 1.0 1988622 ChemDiv2_007630 O=C(Cc1cccs1)Nc2ccc3nc4CCCCCn4c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K19 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988623 ChemDiv2_007631 CC1CCCCC1NC(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K20 compound treatment 0.255 0.0135 0.73 0.7255 1.0 1988624 ChemDiv2_007632 CN(CC(=O)N1CCCCC1)S(=O)(=O)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K21 compound treatment 0.265 0.0235 1.26 1.2628 1.0 1988625 ChemDiv2_007633 OC(=O)C1CCN(CC1)C(=O)c2cc3sccc3n2Cc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K22 compound treatment 0.347 0.106 5.67 5.6693 1.0 1988626 ChemDiv2_007634 O=C(NCc1ccccn1)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K23 mock treatment 0.243 0.0015 0.08 0.0806 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 K24 mock treatment 0.248 0.0065 0.35 0.3493 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L01 compound treatment 0.352 0.111 5.94 5.938 1.0 1988627 ChemDiv2_007635 O=C(NCCc1ccsc1)c2ccc3c(=O)n4CCCCCc4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L02 compound treatment 0.255 0.0135 0.73 0.7255 1.0 1988628 ChemDiv2_007636 O=C(Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O)N5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L03 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988629 ChemDiv2_007637 O=C(Cn1cccc1C(=O)c2ccccc2)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L04 compound treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1988630 ChemDiv2_007638 CNC(=O)Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L05 compound treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1988631 ChemDiv2_007639 Cc1ccccc1C(=O)c2cccn2CC(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L06 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988632 ChemDiv2_007640 CCN1CCCC1CNC(=O)Cn2ncc3c4ccccc4n(Cc5ccc(F)cc5)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L07 compound treatment 0.577 0.336 18.03 18.0291 1.0 1988633 ChemDiv2_007641 CCOC(=O)c1ccc(NC(=O)C2CCN(CC2)c3nnc(s3)n4cccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L08 compound treatment 0.251 0.0095 0.51 0.5105 1.0 1988634 ChemDiv2_007642 COC(=O)c1ccccc1NC(=O)Cn2cc3CCCCc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L09 compound treatment 0.461 0.22 11.8 11.7955 1.0 1988635 ChemDiv2_007643 CC(C)NC(=O)C1CCCN(C1)c2nnc(s2)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L10 compound treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1988636 ChemDiv2_007644 O=C(Cn1cc2CCCCCc2n1)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L11 compound treatment 0.456 0.215 11.53 11.5268 1.0 1988637 ChemDiv2_007645 O=C(NCCCN1CCCC1=O)c2ccc3nc(sc3c2)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L12 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988638 ChemDiv2_007646 Cc1nn(CC(=O)NCCc2ccccc2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L13 compound treatment 0.272 0.0305 1.64 1.639 1.0 1988639 ChemDiv2_007647 COC(=O)c1ccccc1NC(=O)CN2C(=O)CSc3ncccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L14 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988640 ChemDiv2_007648 CCC(C(=O)N1CCCC1)n2nc(C)n3c4ccoc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L15 compound treatment 0.487 0.246 13.19 13.1927 1.0 1988641 ChemDiv2_007649 Cc1cc(NC(=O)CC(=O)Nc2ccc3nc4CCCCCn4c(=O)c3c2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L16 compound treatment 0.294 0.0525 2.82 2.8212 1.0 1988642 ChemDiv2_007650 CC(NC(=O)CCCn1c(C)c2cnn(c3ccccc3)c(=O)c2c1C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L17 compound treatment 0.436 0.195 10.45 10.452 1.0 1988643 ChemDiv2_007651 Cc1oc(nc1CSc2nc3ccncc3[nH]2)c4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L18 compound treatment 0.338 0.0965 5.19 5.1857 1.0 1988644 ChemDiv2_007652 Cc1n(Cc2ccc(C)cc2)c(C)c3c(=O)n(CC(=O)NCCCN4CCCCCC4)ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L19 compound treatment 0.326 0.0845 4.54 4.5409 1.0 1988645 ChemDiv2_007653 CN(C(=O)Cn1c(SCc2cccc(F)c2)nc3ccncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L20 compound treatment 0.351 0.11 5.88 5.8843 1.0 1988646 ChemDiv2_007654 COC(=O)c1ccccc1NC(=O)c2cc3CS(=O)(=O)c4ccccc4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L21 compound treatment 0.522 0.281 15.07 15.0735 1.0 1988647 ChemDiv2_007655 Fc1ccc(Cn2c(SCc3ccc(cc3)C(=O)NCc4ccccn4)nc5ccncc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L22 compound treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1988648 ChemDiv2_007656 CC(NC(=O)CCc1c(C)nc2n(nc(C)c2c1C)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L23 mock treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 L24 mock treatment 0.245 0.0035 0.19 0.1881 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M01 compound treatment 0.232 -0.0095 -0.51 -0.5105 -1.0 1988649 ChemDiv2_007657 COC(=O)c1cc2sccc2n1CC(=O)Nc3ccc(OC)c(OC)c3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M02 compound treatment 0.278 0.0365 1.96 1.9614 1.0 1988650 ChemDiv2_007658 CC1CCCCN1c2nnc(NC(=O)Cn3c(=O)oc4ccccc34)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M03 compound treatment 0.247 0.0055 0.3 0.2956 1.0 1988651 ChemDiv2_007659 CCC(C(=O)NC1CCCC1)n2c(cc3ccsc23)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M04 compound treatment 0.23 -0.0115 -0.62 -0.618 -1.0 1988652 ChemDiv2_007660 O=C(Cn1c2ccccc2c3cn[nH]c(=O)c13)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M05 compound treatment 0.288 0.0465 2.5 2.4988 1.0 1988653 ChemDiv2_007661 CC1CCCCC1NC(=O)c2ccc(CSc3nc4cnccc4[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M06 compound treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1988654 ChemDiv2_007662 CC1CC(C)CN(CCCNC(=O)Cn2ncn3cccc3c2=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M07 compound treatment 0.405 0.164 8.79 8.7861 1.0 1988655 ChemDiv2_007663 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M08 compound treatment 0.505 0.264 14.16 14.1599 1.0 1988656 ChemDiv2_007664 CCOc1cc2sc(nc2cc1Br)N3CCC(CC3)C(=O)NCCCN4CCN(C)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M09 compound treatment 0.265 0.0235 1.26 1.2628 1.0 1988657 ChemDiv2_007665 CCN1CCCC1CNC(=O)C2=CCN(CC2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M10 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988658 ChemDiv2_007666 Cc1cc(c2ccco2)n(CC(=O)NCCCc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M11 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988659 ChemDiv2_007667 CCC(C(=O)N1CCc2ccccc2C1)n3nc(C)n4c5ccsc5cc4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M12 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988660 ChemDiv2_007668 CC(C)(C)C1CCc2nc3ccc(cc3c(C(=O)O)c2C1)S(=O)(=O)N4CCC(CC4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M13 compound treatment 0.261 0.0195 1.05 1.0479 1.0 1988661 ChemDiv2_007669 CCc1nn(CC(=O)NC(C)c2ccc3OCCOc3c2)c(=O)c4cc5sccc5n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M14 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1679057 ChemDiv2_007670 O=c1n(Cc2ccccc2)cnc3n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M15 compound treatment 0.454 0.212 11.42 11.4193 1.0 1988662 ChemDiv2_007671 Cc1nn(CCCC(=O)NCC2CCCO2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M16 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988663 ChemDiv2_007672 Cc1cc(NC(=O)Cn2cnc3n(ncc3c2=O)c4ccc(Cl)cc4)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M17 compound treatment 0.59 0.348 18.73 18.7277 1.0 1988664 ChemDiv2_007673 CCN1CCCC1CNC(=O)c2ccc3Sc4ccccc4C(=O)Nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M18 compound treatment 0.42 0.178 9.59 9.5922 1.0 1988665 ChemDiv2_007674 O=C(CCS(=O)(=O)c1ccccc1)Nc2ccc3nc4CCCCCn4c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M19 compound treatment 0.255 0.0135 0.73 0.7255 1.0 1988666 ChemDiv2_007675 CCOc1ccc(CCNC(=O)Cn2ncc3ccccc23)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M20 compound treatment 0.27 0.0285 1.53 1.5315 1.0 1988667 ChemDiv2_007676 COc1ccc(cc1)c2noc(n2)N(C)CC(=O)Nc3cccc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M21 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988668 ChemDiv2_007677 CCn1c(cc2occc12)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M22 compound treatment 0.268 0.0265 1.42 1.4241 1.0 1988669 ChemDiv2_007678 O=C(NCc1ccc2OCOc2c1)c3ccc4c(=O)n5CCCCCc5nc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M23 mock treatment 0.247 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 M24 mock treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N01 compound treatment 0.459 0.218 11.69 11.688 1.0 1988670 ChemDiv2_007679 O=C(NCCCN1CCCC1)c2cc3CSc4ccccc4-c3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N02 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988671 ChemDiv2_007680 O=C(Cn1ncc2c3ccccc3n(Cc4ccccc4)c2c1=O)NC5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N03 compound treatment 0.239 -0.0025 -0.13 -0.1343 -1.0 1988672 ChemDiv2_007681 CCN1CCCC1CNC(=O)Cn2cccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N04 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988673 ChemDiv2_007682 Cc1ccccc1Cn2c3ccccc3c4cnn(CC(=O)NCC5CCCO5)c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N05 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988674 ChemDiv2_007683 CC1CCCC(NC(=O)Cn2cccc2C(=O)c3ccccc3C)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N06 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988675 ChemDiv2_007684 CC1CCCCN1CCCNC(=O)Cn2ncc3c4ccccc4n(Cc5ccc(F)cc5)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N07 compound treatment 0.478 0.236 12.71 12.709 1.0 1988676 ChemDiv2_007685 O=C(NC1CC1)C2CCN(CC2)c3nnc(s3)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N08 compound treatment 0.29 0.0485 2.61 2.6063 1.0 1988677 ChemDiv2_007686 CCOC(=O)c1ccc(NC(=O)Cn2cc3CCCCc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N09 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1988678 ChemDiv2_007687 O=C(NCc1ccccc1)c2ccc3nc(sc3c2)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N10 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988679 ChemDiv2_007688 O=C(Cn1cc2CCCCCc2n1)NCCCN3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N11 compound treatment 0.32 0.0785 4.22 4.2184 1.0 1988680 ChemDiv2_007689 Cc1ccc(NC(=O)c2ccc3nc(sc3c2)N4CCOCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N12 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988681 ChemDiv2_007690 CCc1nn(CC(=O)N(C)Cc2ccccc2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N13 compound treatment 0.247 0.0055 0.3 0.2956 1.0 1988682 ChemDiv2_007691 CNC(=O)CN1C(=O)CSc2ncccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N14 compound treatment 0.265 0.0235 1.26 1.2628 1.0 1988683 ChemDiv2_007692 Cc1oc(nc1Cn2ncn3c(cc4ccccc43)c2=O)c5cccc(Cl)c5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N15 compound treatment 0.449 0.207 11.15 11.1506 1.0 1988684 ChemDiv2_007693 COc1ccc(Cl)cc1NC(=O)CC(=O)Nc2ccc3nc4CCCCCn4c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N16 compound treatment 0.298 0.0565 3.04 3.0362 1.0 1988685 ChemDiv2_007694 Cc1n(CCCC(=O)NC2CC2)c(C)c3c(=O)n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N17 compound treatment 0.461 0.22 11.8 11.7955 1.0 1988686 ChemDiv2_007695 CCN(C(=O)CSc1nc2ccncc2[nH]1)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N18 compound treatment 0.259 0.0175 0.94 0.9404 1.0 1988687 ChemDiv2_007696 CC(NC(=O)Cn1ncc2c(C)n(Cc3ccc(C)cc3)c(C)c2c1=O)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N19 compound treatment 0.404 0.163 8.73 8.7324 1.0 1988688 ChemDiv2_007697 CCC(C(=O)Nc1ccccc1OC)n2c(SCc3cccc(F)c3)nc4ccncc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N20 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988689 ChemDiv2_007698 CCCCN(C)C(=O)c1cc2CS(=O)(=O)c3ccccc3-c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N21 compound treatment 0.243 0.0015 0.08 0.0806 1.0 1988690 ChemDiv2_007699 Cn1c2ccccc2c3cnn(CC(=O)N4CCc5ccccc45)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N22 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988691 ChemDiv2_007700 Cc1cc(C)c2c(nn3c(C)c(CCC(=O)NCC4CCCO4)c(C)nc23)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N23 mock treatment 0.244 0.0025 0.13 0.1343 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 N24 mock treatment 0.234 -0.0075 -0.4 -0.403 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O01 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988692 ChemDiv2_007701 COC(=O)c1cc2sccc2n1CC(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O02 compound treatment 0.254 0.0125 0.67 0.6717 1.0 1988693 ChemDiv2_007702 Cn1c(cc2sccc12)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O03 compound treatment 0.301 0.0595 3.2 3.1974 1.0 1988694 ChemDiv2_007703 Cn1c(cc2sccc12)C(=O)N3CCCC(C3)C(=O)NCCc4ccc(cc4)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O04 compound treatment 0.231 -0.0105 -0.56 -0.5642 -1.0 1988695 ChemDiv2_007704 CCC(C)NC(=O)C1CCN(CC1)C(=O)c2sccc2n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O05 compound treatment 0.456 0.215 11.53 11.5268 1.0 1988696 ChemDiv2_007705 O=C(NCc1cccs1)c2ccc(CSc3nc4cnccc4[nH]3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O06 compound treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1988697 ChemDiv2_007706 CC(C(=O)NCCCN1CC(C)CC(C)C1)n2nc(C)c3sc4ccccc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O07 compound treatment 0.34 0.0985 5.29 5.2932 1.0 1988698 ChemDiv2_007707 CCOc1ccc2nc(sc2c1)N3CCC(CC3)C(=O)NCCc4ccc(OC)cc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O08 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988699 ChemDiv2_007708 Fc1ccccc1Cn2ncn3c(cc4ccccc43)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O09 compound treatment 0.262 0.0205 1.1 1.1016 1.0 1988700 ChemDiv2_007709 CC(C)N(Cc1ccccc1)C(=O)C2=CCN(CC2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O10 compound treatment 0.237 -0.0045 -0.24 -0.2418 -1.0 1988701 ChemDiv2_007710 Cc1cc(c2ccco2)n(CC(=O)NCc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O11 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988702 ChemDiv2_007711 CC(C)NC(=O)C(C)n1nc(C)n2c3ccsc3cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O12 compound treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1988703 ChemDiv2_007712 O=C(Cn1cnc2n(ncc2c1=O)c3ccccc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O13 compound treatment 0.262 0.0205 1.1 1.1016 1.0 1988704 ChemDiv2_007713 CCc1nn(CC(=O)N2CCCCCC2)c(=O)c3cc4sccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O14 compound treatment 0.246 0.0045 0.24 0.2418 1.0 1988705 ChemDiv2_007714 CC(c1ccccc1)n2cnc3n(ncc3c2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O15 compound treatment 0.292 0.0505 2.71 2.7138 1.0 1988706 ChemDiv2_007715 CCN1CCCC1CNC(=O)CCCn2nc(C)n3c4ccsc4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O16 compound treatment 0.244 0.0025 0.13 0.1343 1.0 1988707 ChemDiv2_007716 CCOC(=O)C(CC)n1cnc2n(ncc2c1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O17 compound treatment 0.294 0.0525 2.82 2.8212 1.0 1988708 ChemDiv2_007717 Cc1onc(c1C(=O)Nc2nnc(s2)N3CCCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O18 compound treatment 0.463 0.222 11.9 11.9029 1.0 1988709 ChemDiv2_007718 COCC(=O)Nc1ccc2nc3CCCCCn3c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O19 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988710 ChemDiv2_007719 CCOC(=O)C1CCN(CC1)C(=O)Cn2ncc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O20 compound treatment 0.242 5.0E-4 0.03 0.0269 1.0 1988711 ChemDiv2_007720 COc1ccc(cc1)c2noc(n2)N(C)CC(=O)NCCC3=CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O21 compound treatment 0.26 0.0185 0.99 0.9942 1.0 1988712 ChemDiv2_007721 CCc1nn(CC(=O)NCc2ccc(OC)c(OC)c2)c(=O)c3cc4occc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O22 compound treatment 0.256 0.0145 0.78 0.7792 1.0 1988713 ChemDiv2_007722 CCN(C(=O)c1ccc2c(=O)n3CCCCCc3nc2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O23 mock treatment 0.247 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 O24 mock treatment 0.257 0.0155 0.83 0.8329 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P01 compound treatment 0.281 0.0395 2.12 2.1226 1.0 1988714 ChemDiv2_007723 CN(CC(=O)NCc1ccc2OCOc2c1)S(=O)(=O)c3ccc4nc(C)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P02 compound treatment 0.253 0.0115 0.62 0.618 1.0 1988715 ChemDiv2_007724 Fc1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5)c3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P03 compound treatment 0.238 -0.0035 -0.19 -0.1881 -1.0 1988716 ChemDiv2_007725 CNC(=O)Cn1cccc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P04 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1988717 ChemDiv2_007726 CN1CCN(CCNC(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5C)c3c2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P05 compound treatment 0.233 -0.0085 -0.46 -0.4568 -1.0 1988718 ChemDiv2_007727 CC(C(=O)NCc1ccccn1)n2cccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P06 compound treatment 0.254 0.0125 0.67 0.6717 1.0 1988719 ChemDiv2_007728 CN(Cc1ccccc1)C(=O)Cn2ncc3c4ccccc4n(Cc5ccccc5F)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P07 compound treatment 0.49 0.249 13.35 13.3539 1.0 1988720 ChemDiv2_007729 O=C(NCCc1ccccc1)C2CCN(CC2)c3nnc(s3)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P08 compound treatment 0.257 0.0155 0.83 0.8329 1.0 1988721 ChemDiv2_007730 O=C(Cn1cc2CCCCc2n1)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P09 compound treatment 0.252 0.0105 0.56 0.5642 1.0 1988722 ChemDiv2_007731 CN(Cc1ccccc1)C(=O)c2ccc3nc(sc3c2)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P10 compound treatment 0.226 -0.0155 -0.83 -0.8329 -1.0 1988723 ChemDiv2_007732 CC1CCCCC1NC(=O)Cn2cc3CCCCCc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P11 compound treatment 0.241 -5.0E-4 -0.03 -0.0269 -1.0 1988724 ChemDiv2_007733 CCOC(=O)N1CCC(CC1)NC(=O)c2sc(nc2C)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P12 compound treatment 0.237 -0.0045 -0.24 -0.2418 -1.0 1988725 ChemDiv2_007734 CCc1nn(CC(=O)N2CCN(CC2)c3cc(Cl)ccc3C)c(=O)c4cc5occc5n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P13 compound treatment 0.231 -0.0105 -0.56 -0.5642 -1.0 1988726 ChemDiv2_007735 CCN1CCN(Cc2ccc(NC(=O)CN3C(=O)CSc4ncccc34)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P14 compound treatment 0.245 0.0035 0.19 0.1881 1.0 1988727 ChemDiv2_007736 CNC(=O)c1cc2oc3ccccc3c2n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P15 compound treatment 0.421 0.179 9.65 9.646 1.0 1988728 ChemDiv2_007737 O=C(CC(=O)N1CCCCCC1)Nc2ccc3nc4CCCCCn4c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P16 compound treatment 0.28 0.0385 2.07 2.0689 1.0 1988729 ChemDiv2_007738 Cc1n(CCCC(=O)NCC2CCCO2)c(C)c3c(=O)n(ncc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P17 compound treatment 0.274 0.0325 1.75 1.7465 1.0 1988730 ChemDiv2_007739 CCC(Sc1nc2ccncc2[nH]1)C(=O)Nc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P18 compound treatment 0.24 -0.0015 -0.08 -0.0806 -1.0 1988731 ChemDiv2_007740 Cc1n(Cc2ccc(F)cc2)c(C)c3c(=O)n(CC(=O)N4CCc5ccccc45)ncc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P19 compound treatment 0.249 0.0075 0.4 0.403 1.0 1988732 ChemDiv2_007741 CCC(C(=O)NC1CCCC1)n2c(SCc3cccc(F)c3)nc4ccncc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P20 compound treatment 0.251 0.0095 0.51 0.5105 1.0 1988733 ChemDiv2_007742 CCN(CC)C(=O)c1cc2CS(=O)(=O)c3ccccc3-c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P21 compound treatment 0.248 0.0065 0.35 0.3493 1.0 1988734 ChemDiv2_007743 CCCCN(CC)C(=O)Cn1ncc2c3ccccc3n(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P22 compound treatment 0.253 0.0115 0.62 0.618 1.0 1988735 ChemDiv2_007744 Cc1cc(C)c2c(nn3c(C)c(CCC(=O)Nc4ccc5OCOc5c4)c(C)nc23)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P23 mock treatment 0.235 -0.0065 -0.35 -0.3493 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1390 P24 mock treatment 0.223 -0.0185 -0.99 -0.9942 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A01 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988736 ChemDiv2_007745 CC(C(=O)Nc1cccc(Cl)c1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A02 compound treatment 0.309 0.0809 4.35 4.3461 1.0 1988737 ChemDiv2_007746 CC(C(=O)N1CCC(C)CC1)n2c3ccccc3c4nc(=O)cc(C)n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A03 compound treatment 0.294 0.0659 3.54 3.54 1.0 1988738 ChemDiv2_007747 CN(Cc1ccccc1)C(=O)CNS(=O)(=O)c2ccc3nc(C)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A04 compound treatment 0.281 0.0529 2.84 2.8414 1.0 1988739 ChemDiv2_007748 COc1cc(NC(=O)CSCc2cnn(c2n3cccc3)c4ccccc4)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A05 compound treatment 0.243 0.0149 0.8 0.7994 1.0 1988740 ChemDiv2_007749 NC(=O)c1nc(nc2n(c3ccccc3)c(=O)[nH]c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A06 compound treatment 0.451 0.223 11.98 11.9768 1.0 1988741 ChemDiv2_007750 O=C(NCCc1c[nH]c2ccccc12)C3CCN(CC3)c4nnc(s4)N5CCCC5=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A07 compound treatment 0.219 -0.00912 -0.49 -0.4904 -1.0 1988742 ChemDiv2_007751 Cc1nn(c2ccc(C)cc2)c3nc(C)c(CCC(=O)NCc4ccc5OCOc5c4)c(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A08 compound treatment 0.294 0.0659 3.54 3.54 1.0 1988743 ChemDiv2_007752 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2cc(Br)cnc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A09 compound treatment 0.281 0.0529 2.84 2.8414 1.0 1988744 ChemDiv2_007753 Cc1ccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCC4)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A10 compound treatment 0.363 0.135 7.25 7.2479 1.0 1988745 ChemDiv2_007754 Clc1cccc(c1)N2CCN(CCCNC(=O)c3nc(no3)c4ccncc4)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A11 compound treatment 0.286 0.0579 3.11 3.1101 1.0 1988746 ChemDiv2_007755 OCCN(C(=O)c1ccc2snnc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A12 compound treatment 0.246 0.0179 0.96 0.9606 1.0 1988747 ChemDiv2_007756 Oc1ccc(Cl)cc1N2C(SCC2=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A13 compound treatment 0.294 0.0659 3.54 3.54 1.0 1988748 ChemDiv2_007757 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A14 compound treatment 0.458 0.23 12.35 12.353 1.0 1988749 ChemDiv2_007758 CCOc1cc2[nH]c(=O)n(CCCN3CCCC3=O)c(=O)c2cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A15 compound treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1988750 ChemDiv2_007759 Cc1ccc2[nH]c3c(=O)n(CCCN4CCCC4)cnc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A16 compound treatment 0.255 0.0269 1.44 1.4442 1.0 1988751 ChemDiv2_007760 O=C(NC1CCCCC1)c2ccc3c(=O)n(CC4CCCO4)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A17 compound treatment 0.259 0.0309 1.66 1.6592 1.0 1988752 ChemDiv2_007761 C=CCn1c(NCc2cccs2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A18 compound treatment 0.232 0.00388 0.21 0.2082 1.0 1988753 ChemDiv2_007762 CCOc1ccccc1NC(=O)c2cc3c(CO)cnc(C)c3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A19 compound treatment 0.286 0.0579 3.11 3.1101 1.0 1988754 ChemDiv2_007763 COc1ccc2[nH]cc(CCNS(=O)(=O)c3ccc(c(OC)c3)n4cnnn4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A20 compound treatment 0.322 0.0939 5.04 5.0446 1.0 1988755 ChemDiv2_007764 Cc1ccc(NC(=O)c2sc(=S)n3c2[nH]c(=O)c4ccccc43)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A21 compound treatment 0.26 0.0319 1.71 1.7129 1.0 1988756 ChemDiv2_007765 Cc1cc(=O)nc2c3ccccc3n(CC(=O)N4CCc5ccccc45)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A22 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1988757 ChemDiv2_007766 COc1ccccc1NC(=O)CSc2nc3ccccc3c4nc5ccccc5n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A23 mock treatment 0.238 0.00987 0.53 0.5307 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 A24 mock treatment 0.239 0.0109 0.58 0.5844 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B01 compound treatment 0.237 0.00887 0.48 0.4769 1.0 1988758 ChemDiv2_007767 ClCCC1=Nc2ccccc2S(=O)(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B02 compound treatment 0.245 0.0169 0.91 0.9068 1.0 1988759 ChemDiv2_007768 CC1CCCCN1C(=O)CSc2nc3cc4OCOc4cc3c(=O)n2Cc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B03 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1988760 ChemDiv2_007769 COc1cccc(NC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CCCN5CCOCC5)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B04 compound treatment 0.287 0.0589 3.16 3.1638 1.0 1988761 ChemDiv2_007770 CCCCn1c(SC(CC)C(=O)Nc2ccc3OCOc3c2)nc4ccc(cc4c1=O)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B05 compound treatment 0.381 0.153 8.22 8.2152 1.0 1988762 ChemDiv2_007771 CSc1nc2c3ccccc3sc2c(=O)n1CC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B06 compound treatment 0.293 0.0649 3.49 3.4862 1.0 1988763 ChemDiv2_007772 CCOC(=O)c1sc(=S)n(c1N)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B07 compound treatment 0.356 0.128 6.87 6.8717 1.0 1623219 ChemDiv2_007773 CCOC(=O)CSc1nc2ccccc2c(=O)n1Cc3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B08 compound treatment 0.289 0.0609 3.27 3.2713 1.0 1719596 ChemDiv2_007774 CCOc1ccc(NC(=O)CSc2nc3ccsc3c(=O)n2c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B09 compound treatment 0.239 0.0109 0.58 0.5844 1.0 1666476 ChemDiv2_007775 O=C(CSc1nc2ccccc2c(=O)n1CCc3ccccc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B10 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1375395 ChemDiv2_007776 CCCCn1c(SCC(=O)Nc2nccs2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B11 compound treatment 0.494 0.266 14.29 14.2876 1.0 1467112 ChemDiv2_007777 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc4ccc5OCOc5c4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B12 compound treatment 0.315 0.0869 4.67 4.6685 1.0 1316321 ChemDiv2_007778 CCCCn1c(SCC(=O)NCc2ccc(C)cc2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B13 compound treatment 0.433 0.205 11.01 11.0096 1.0 1499225 ChemDiv2_007779 CC(=O)NCCn1c(SCc2ccccc2Cl)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B14 compound treatment 0.41 0.182 9.77 9.7736 1.0 1988764 ChemDiv2_007780 Fc1ccc(cc1)C(=O)CSc2nc3ccsc3c(=O)n2CCCC(=O)NCc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B15 compound treatment 0.329 0.101 5.42 5.4208 1.0 1590146 ChemDiv2_007781 CCN(CCCn1c(SCC#N)nc2ccccc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B16 compound treatment 0.444 0.216 11.6 11.6007 1.0 1988765 ChemDiv2_007782 CCC(Sc1nc2ccsc2c(=O)n1Cc3ccc(cc3)C(=O)O)C(=O)Nc4cccc(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B17 compound treatment 0.3 0.0719 3.86 3.8624 1.0 1497057 ChemDiv2_007783 CCCN(CCC)C(=O)CSc1nc2ccccc2c(=O)n1C3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B18 compound treatment 0.219 -0.00912 -0.49 -0.4904 -1.0 1988766 ChemDiv2_007784 CN(C)C(=O)c1sc2n(CC(=O)N(C)c3ccccc3)c(=O)n(c4ccccc4)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B19 compound treatment 0.433 0.205 11.01 11.0096 1.0 1204209 ChemDiv2_007785 O=C(CCCn1c(SCC#N)nc2ccccc2c1=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B20 compound treatment 0.228 -1.25E-4 -0.01 -0.0067 -1.0 1561033 ChemDiv2_007786 COc1cc(OC)cc(c1)c2n[nH]c(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B21 compound treatment 0.281 0.0529 2.84 2.8414 1.0 1395047 ChemDiv2_007787 O=C(CSc1nc2ccccc2c(=O)n1CC3CCC(CC3)C(=O)NCc4ccccc4)Nc5nccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B22 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988767 ChemDiv2_007788 C(NC1CCCC1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B23 mock treatment 0.225 -0.00312 -0.17 -0.1679 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 B24 mock treatment 0.22 -0.00812 -0.44 -0.4366 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C01 compound treatment 0.217 -0.0111 -0.6 -0.5978 -1.0 1988768 ChemDiv2_007789 CC(C(=O)N1CCc2ccccc12)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C02 compound treatment 0.241 0.0129 0.69 0.6919 1.0 1988769 ChemDiv2_007790 CC(C)NC(=O)C(C)n1c2ccccc2c3nc(=O)cc(C)n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C03 compound treatment 0.317 0.0889 4.78 4.776 1.0 1988770 ChemDiv2_007791 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C04 compound treatment 0.265 0.0369 1.98 1.9816 1.0 1988771 ChemDiv2_007792 O=C(CSCc1cnn(c1n2cccc2)c3ccccc3)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C05 compound treatment 0.25 0.0219 1.18 1.1755 1.0 1988772 ChemDiv2_007793 NC(=O)c1nc(nc2n(c3ccccc3)c(=O)[nH]c12)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C06 compound treatment 0.242 0.0139 0.75 0.7456 1.0 1988773 ChemDiv2_007794 CCOC(=O)N1CCN(CC1)C(=O)C(CC)n2nc(C)c3sc4ccccc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C07 compound treatment 0.411 0.183 9.83 9.8273 1.0 1988774 ChemDiv2_007795 Cc1nn(c2ccc(C)cc2)c3nc(C)c(CCC(=O)N4CCCC4)c(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C08 compound treatment 0.221 -0.00712 -0.38 -0.3829 -1.0 1988775 ChemDiv2_007796 O=c1cc([nH]c(=O)n1C2CCCCC2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C09 compound treatment 0.232 0.00388 0.21 0.2082 1.0 1988776 ChemDiv2_007797 CS(=O)(=O)NCc1cn2ccsc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C10 compound treatment 0.22 -0.00812 -0.44 -0.4366 -1.0 1988777 ChemDiv2_007798 CCCCC1NC(CS1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C11 compound treatment 0.23 0.00188 0.1 0.1008 1.0 1988778 ChemDiv2_007799 CC(C)N(C(C)C)C(=O)c1ccc2snnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C12 compound treatment 0.287 0.0589 3.16 3.1638 1.0 1988779 ChemDiv2_007800 CCOC(=O)N1CCC(CC1)NC(=O)c2ccc3nc(c4cccs4)c(nc3c2)c5cccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C13 compound treatment 0.541 0.313 16.81 16.8132 1.0 1988780 ChemDiv2_007801 O=C(NCCCN1CCCC1=O)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C14 compound treatment 0.233 0.00488 0.26 0.262 1.0 1087114 ChemDiv2_007802 O=c1[nH]c2ccccc2c(=O)n1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C15 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1988781 ChemDiv2_007803 CN(CCCn1cnc2c3cc(C)ccc3[nH]c2c1=O)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C16 compound treatment 0.283 0.0549 2.95 2.9489 1.0 1988782 ChemDiv2_007804 CC1CCCC(NC(=O)c2ccc3c(=O)n(CC4CCCO4)c(=O)[nH]c3c2)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C17 compound treatment 0.285 0.0569 3.06 3.0563 1.0 1988783 ChemDiv2_007805 CC(=O)NCCc1nc2ccccc2n1CCOc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C18 compound treatment 0.519 0.291 15.63 15.631 1.0 1988784 ChemDiv2_007806 O=c1oc2ccccc2cc1c3nnc(NCc4ccc5OCOc5c4)s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C19 compound treatment 0.243 0.0149 0.8 0.7994 1.0 1988785 ChemDiv2_007807 CC(C(=O)NCc1ccc(C)cc1)n2nc(C)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C20 compound treatment 0.46 0.232 12.46 12.4605 1.0 1339682 ChemDiv2_007808 CN(C)c1ccc(cc1)c2nc(cs2)c3cc4ccc(O)cc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C21 compound treatment 0.273 0.0449 2.41 2.4115 1.0 1988786 ChemDiv2_007809 Cc1cc(=O)nc2c3ccccc3n(CC(=O)N4CCCCC4)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C22 compound treatment 0.235 0.00687 0.37 0.3694 1.0 1988787 ChemDiv2_007810 CCC(C)NC(=O)CSc1nc2ccccc2c3nc4ccccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C23 mock treatment 0.23 0.00188 0.1 0.1008 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 C24 mock treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D01 compound treatment 0.307 0.0789 4.24 4.2386 1.0 1988788 ChemDiv2_007811 NC(=O)CCCC1=Nc2ccccc2S(=O)(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D02 compound treatment 0.238 0.00987 0.53 0.5307 1.0 1988789 ChemDiv2_007812 CCN(CC)C(=O)CSc1nc2cc3OCOc3cc2c(=O)n1CCC4=CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D03 compound treatment 0.276 0.0479 2.57 2.5727 1.0 1988790 ChemDiv2_007813 O=C(CSc1nc2c3ccccc3sc2c(=O)n1CCCN4CCOCC4)NC5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D04 compound treatment 0.522 0.294 15.79 15.7922 1.0 1988791 ChemDiv2_007814 CC1CCCCN1C(=O)CSc2nc3ccccc3c(=O)n2Cc4ccc(cc4)C(=O)NCc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D05 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1988792 ChemDiv2_007815 CCSc1nc2c3ccccc3sc2c(=O)n1C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D06 compound treatment 0.27 0.0419 2.25 2.2503 1.0 1988793 ChemDiv2_007816 CCOC(=O)c1sc(=S)n(c1N)c2ccc(F)cc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D07 compound treatment 0.399 0.171 9.18 9.1825 1.0 1489649 ChemDiv2_007817 COc1ccccc1Cn2c(SC)nc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D08 compound treatment 0.296 0.0679 3.65 3.6475 1.0 1730725 ChemDiv2_007818 COc1cccc(NC(=O)CSc2nc3ccsc3c(=O)n2Cc4ccccc4Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D09 compound treatment 0.245 0.0169 0.91 0.9068 1.0 1176670 ChemDiv2_007819 O=C(CSc1nc2ccccc2c(=O)n1Cc3ccccc3)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D10 compound treatment 0.361 0.133 7.14 7.1404 1.0 1599493 ChemDiv2_007820 CCCCn1c(SCC(=O)N(CC)c2cccc(C)c2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D11 compound treatment 0.458 0.23 12.35 12.353 1.0 1270045 ChemDiv2_007821 CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc4ccc(cc4)S(=O)(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D12 compound treatment 0.323 0.0949 5.1 5.0984 1.0 1608521 ChemDiv2_007822 CCCCn1c(SCc2ccccc2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D13 compound treatment 0.235 0.00687 0.37 0.3694 1.0 1169279 ChemDiv2_007823 CC(=O)NCCn1c(SCC(=O)NC2CCCCC2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D14 compound treatment 0.312 0.0839 4.51 4.5073 1.0 1988794 ChemDiv2_007824 OC(=O)C1CCC(Cn2c(SCC(=O)c3ccc(F)cc3)nc4ccsc4c2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D15 compound treatment 0.354 0.126 6.76 6.7643 1.0 1278878 ChemDiv2_007825 CC(=O)NCCn1c(SCC(=O)Nc2ccccc2Cl)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D16 compound treatment 0.269 0.0409 2.2 2.1965 1.0 1988795 ChemDiv2_007826 O=C(CSc1nc2ccsc2c(=O)n1Cc3ccccn3)Nc4nccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D17 compound treatment 0.435 0.207 11.12 11.117 1.0 1677628 ChemDiv2_007827 CCCN(CCC)C(=O)CSc1nc2ccccc2c(=O)n1Cc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D18 compound treatment 0.236 0.00787 0.42 0.4232 1.0 1988796 ChemDiv2_007828 CCN(CC)C(=O)c1sc2n(CC(=O)C(C)(C)C)c(=O)n(Cc3ccccc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D19 compound treatment 0.488 0.26 13.97 13.9651 1.0 1305916 ChemDiv2_007829 Clc1ccccc1CSc2nc3ccccc3c(=O)n2CCCC(=O)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D20 compound treatment 0.288 0.0599 3.22 3.2176 1.0 1625272 ChemDiv2_007830 Cc1cc(ccc1Br)N2S(=O)(=O)c3ccccc3S2(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D21 compound treatment 0.308 0.0799 4.29 4.2923 1.0 1988797 ChemDiv2_007831 O=C(CSc1nc2ccccc2c(=O)n1C3CC3)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D22 compound treatment 0.241 0.0129 0.69 0.6919 1.0 1988798 ChemDiv2_007832 CC(C)NCc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D23 mock treatment 0.214 -0.0141 -0.76 -0.759 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 D24 mock treatment 0.223 -0.00512 -0.28 -0.2754 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E01 compound treatment 0.264 0.0359 1.93 1.9278 1.0 1988799 ChemDiv2_007833 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)Nc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E02 compound treatment 0.231 0.00288 0.15 0.1545 1.0 1988800 ChemDiv2_007834 COc1cc2n(CC(=O)NC3CCCCCC3)n4c(C)cc(=O)nc4c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E03 compound treatment 0.487 0.259 13.91 13.9114 1.0 1988801 ChemDiv2_007835 CCOC(=O)c1cccc(NC(=O)CNS(=O)(=O)c2ccc3nc(C)sc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E04 compound treatment 0.292 0.0639 3.43 3.4325 1.0 1988802 ChemDiv2_007836 CCc1cccc(C)c1NC(=O)CSCc2cnn(c2n3cccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E05 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988803 ChemDiv2_007837 CC(C)Cc1nc(C(=O)N)c2[nH]c(=O)n(c3cccc(Cl)c3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E06 compound treatment 0.438 0.21 11.28 11.2782 1.0 1988804 ChemDiv2_007838 CN1CCC(=CC1)c2noc(CCC(=O)Nc3nc4ccccc4s3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E07 compound treatment 0.288 0.0599 3.22 3.2176 1.0 1988805 ChemDiv2_007839 CC(CCc1ccco1)NC(=O)CCc2c(C)nc3n(nc(C)c3c2C)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E08 compound treatment 0.248 0.0199 1.07 1.068 1.0 1988806 ChemDiv2_007840 COc1ccc(cc1)N2CCN(CC2)C(CNC(=O)C3CCCCC3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E09 compound treatment 0.437 0.209 11.22 11.2245 1.0 1988807 ChemDiv2_007841 O=C(NC1=NCCS1)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E10 compound treatment 0.367 0.139 7.46 7.4629 1.0 1988808 ChemDiv2_007842 CCCc1noc(n1)c2ccc(CCC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E11 compound treatment 0.332 0.104 5.58 5.582 1.0 1988809 ChemDiv2_007843 O=C(NCc1ccc2OCOc2c1)c3ccc4snnc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E12 compound treatment 0.465 0.237 12.73 12.7292 1.0 1988810 ChemDiv2_007844 COc1ccc(cc1OC)c2nc3ccc(cc3nc2c4ccc(OC)c(OC)c4)C(=O)NCc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E13 compound treatment 0.408 0.18 9.67 9.6661 1.0 1988811 ChemDiv2_007845 CC(C)NC(=O)c1ccc2snnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E14 compound treatment 0.258 0.0299 1.61 1.6054 1.0 1988812 ChemDiv2_007846 CCOc1cc2[nH]c(=O)n(CCCC(=O)O)c(=O)c2cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E15 compound treatment 0.256 0.0279 1.5 1.4979 1.0 1988813 ChemDiv2_007847 CCCN(CCC)CCCn1cnc2c3cc(OC)ccc3[nH]c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E16 compound treatment 0.243 0.0149 0.8 0.7994 1.0 1988814 ChemDiv2_007848 CCC(C)NC(=O)c1ccc2c(=O)n(C3CCCC3)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E17 compound treatment 0.27 0.0419 2.25 2.2503 1.0 1177559 ChemDiv2_007849 CCN(CC)c1ccc2cc(C(=O)O)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E18 compound treatment 0.316 0.0879 4.72 4.7222 1.0 1399158 ChemDiv2_007850 O=C(CCC(=O)Nc1nc(cs1)c2cc3ccccc3oc2=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E19 compound treatment 0.252 0.0239 1.28 1.283 1.0 1988815 ChemDiv2_007851 CC(C(=O)NCCc1ccccc1)n2nc(C)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E20 compound treatment 0.51 0.282 15.15 15.1474 1.0 1678536 ChemDiv2_007852 Oc1ccc2cc(c3csc(n3)c4ccccc4Cl)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E21 compound treatment 0.266 0.0379 2.04 2.0353 1.0 1988816 ChemDiv2_007853 COc1cc(OC)c(NC(=O)Cn2c3ccccc3c4nc(=O)cc(C)n24)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E22 compound treatment 0.242 0.0139 0.75 0.7456 1.0 1988817 ChemDiv2_007854 CCC(Sc1nc2ccccc2c3nc4ccccc4n13)C(=O)NCc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E23 mock treatment 0.235 0.00687 0.37 0.3694 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 E24 mock treatment 0.231 0.00288 0.15 0.1545 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F01 compound treatment 0.383 0.155 8.32 8.3227 1.0 1988818 ChemDiv2_007855 O=C(CC1(CC2=Nc3ccccc3S(=O)(=O)N2)CCCC1)NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F02 compound treatment 0.258 0.0299 1.61 1.6054 1.0 1988819 ChemDiv2_007856 CCN(CC)C(=O)CSc1nc2cc(OC)c(OC)cc2c(=O)n1Cc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F03 compound treatment 0.489 0.261 14.02 14.0189 1.0 1988820 ChemDiv2_007857 CCOC(=O)CSc1nc2c3ccccc3sc2c(=O)n1CCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F04 compound treatment 0.445 0.217 11.65 11.6544 1.0 1988821 ChemDiv2_007858 CCC(Sc1nc2cc3OCOc3cc2c(=O)n1Cc4ccc(OC)cc4)C(=O)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F05 compound treatment 0.491 0.263 14.13 14.1264 1.0 1988822 ChemDiv2_007859 CCSc1nc2c3ccccc3sc2c(=O)n1CC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F06 compound treatment 0.52 0.292 15.68 15.6848 1.0 1216480 ChemDiv2_007860 COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(SCc4cccnc4)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F07 compound treatment 0.334 0.106 5.69 5.6895 1.0 1252905 ChemDiv2_007861 CCOc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc4ccccc4OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F08 compound treatment 0.295 0.0669 3.59 3.5937 1.0 1599522 ChemDiv2_007862 CCC(C)NC(=O)CSc1nc2ccsc2c(=O)n1Cc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F09 compound treatment 0.413 0.185 9.93 9.9348 1.0 1188147 ChemDiv2_007863 COCCn1c(SCC(=O)Nc2ccccc2Cl)nc3cc(ccc3c1=O)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F10 compound treatment 0.432 0.204 10.96 10.9558 1.0 1452150 ChemDiv2_007864 COc1ccc(cc1)n2c(SCC(=O)c3ccc(O)c(O)c3)nc4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F11 compound treatment 0.514 0.286 15.36 15.3623 1.0 1585540 ChemDiv2_007865 COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)Nc4ccc(OC)cc4OC)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F12 compound treatment 0.311 0.0829 4.45 4.4535 1.0 1498655 ChemDiv2_007866 CC(C)CCn1c(SCC(=O)NC2CCCC2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F13 compound treatment 0.418 0.19 10.2 10.2035 1.0 1394358 ChemDiv2_007867 CC(=O)NCCn1c(SCc2ccc(C)cc2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F14 compound treatment 0.28 0.0519 2.79 2.7877 1.0 1988823 ChemDiv2_007868 OC(=O)Cn1c(SCC(=O)c2ccc(Br)cc2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F15 compound treatment 0.465 0.237 12.73 12.7292 1.0 1703017 ChemDiv2_007869 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCNC(=O)C)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F16 compound treatment 0.329 0.101 5.42 5.4208 1.0 1988824 ChemDiv2_007870 CCC(Sc1nc2ccsc2c(=O)n1Cc3ccccn3)C(=O)Nc4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F17 compound treatment 0.365 0.137 7.36 7.3554 1.0 1341124 ChemDiv2_007871 CCC1CCCCN1C(=O)CSc2nc3ccccc3c(=O)n2CC4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F18 compound treatment 0.241 0.0129 0.69 0.6919 1.0 1988825 ChemDiv2_007872 CCN(CC)C(=O)c1sc2n(CC(=O)NCC3CCCO3)c(=O)n(Cc4ccccc4)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F19 compound treatment 0.386 0.158 8.48 8.4839 1.0 1421115 ChemDiv2_007873 O=C(CCCn1c(SCC#N)nc2ccccc2c1=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F20 compound treatment 0.576 0.348 18.69 18.6941 1.0 1988826 ChemDiv2_007874 OC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F21 compound treatment 0.279 0.0509 2.73 2.7339 1.0 1988827 ChemDiv2_007875 Fc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F22 compound treatment 0.23 0.00188 0.1 0.1008 1.0 1988828 ChemDiv2_007876 OC(=O)CN1C(=O)COc2cc(ccc12)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F23 mock treatment 0.245 0.0169 0.91 0.9068 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 F24 mock treatment 0.209 -0.0191 -1.03 -1.0277 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G01 compound treatment 0.256 0.0279 1.5 1.4979 1.0 1988829 ChemDiv2_007877 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)NCc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G02 compound treatment 0.233 0.00488 0.26 0.262 1.0 1988830 ChemDiv2_007878 CNC(=O)Cn1c2cc(OC)c(OC)cc2c3nc(=O)cc(C)n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G03 compound treatment 0.459 0.231 12.41 12.4067 1.0 1988831 ChemDiv2_007879 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G04 compound treatment 0.245 0.0169 0.91 0.9068 1.0 1988832 ChemDiv2_007880 O=C(CSCc1cnn(c1n2cccc2)c3ccccc3)NCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G05 compound treatment 0.263 0.0349 1.87 1.8741 1.0 1988833 ChemDiv2_007881 CC(C)c1nc(C(=O)N)c2[nH]c(=O)n(c3ccc(Cl)cc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G06 compound treatment 0.323 0.0949 5.1 5.0984 1.0 1988834 ChemDiv2_007882 CN1CCC(=CC1)c2noc(CCC(=O)Nc3cc(C)on3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G07 compound treatment 0.488 0.26 13.97 13.9651 1.0 1988835 ChemDiv2_007883 Cc1cccc2sc(NC(=O)Cn3c(=O)oc4cc(ccc34)S(=O)(=O)N5CCCC5)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G08 compound treatment 0.257 0.0289 1.55 1.5517 1.0 1988836 ChemDiv2_007884 COc1ccc(cc1)N2CCN(CC2)C(CNS(=O)(=O)c3ccc(Cl)cc3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G09 compound treatment 0.239 0.0109 0.58 0.5844 1.0 1988837 ChemDiv2_007885 CC1Cc2ccccc2N1C(=O)c3ccc4snnc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G10 compound treatment 0.335 0.107 5.74 5.7432 1.0 1988838 ChemDiv2_007886 CCCc1noc(n1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G11 compound treatment 0.492 0.264 14.18 14.1801 1.0 1988839 ChemDiv2_007887 O=C(NC1CC1)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G12 compound treatment 0.432 0.204 10.96 10.9558 1.0 1988840 ChemDiv2_007888 O=C(NC1CCCC1)c2ccc3nc(c4ccco4)c(nc3c2)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G13 compound treatment 0.278 0.0499 2.68 2.6802 1.0 1988841 ChemDiv2_007889 CC(C)(CC(=O)O)Cc1nc(no1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G14 compound treatment 0.523 0.295 15.85 15.846 1.0 1988842 ChemDiv2_007890 CCOc1cc2[nH]c(=O)n(CCCC(=O)N(C)Cc3ccccc3)c(=O)c2cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G15 compound treatment 0.256 0.0279 1.5 1.4979 1.0 1988843 ChemDiv2_007891 COc1ccc2[nH]c3c(=O)n(Cc4ccccc4Cl)cnc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G16 compound treatment 0.415 0.187 10.04 10.0423 1.0 1988844 ChemDiv2_007892 COc1ccc(CCn2c(=O)[nH]c3cc(ccc3c2=O)C(=O)N4CCCCCC4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G17 compound treatment 0.3 0.0719 3.86 3.8624 1.0 1988845 ChemDiv2_007893 COc1ccc(cc1)N2CCN(CC2)S(=O)(=O)c3ccccc3c4nn[nH]n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G18 compound treatment 0.424 0.196 10.53 10.5259 1.0 1988846 ChemDiv2_007894 Brc1ccc2oc(=O)c(cc2c1)c3csc(NC(=O)CCC(=O)N4CCc5ccccc5C4)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G19 compound treatment 0.233 0.00488 0.26 0.262 1.0 1988847 ChemDiv2_007895 CCC(C)NC(=O)C(C)n1nc(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G20 compound treatment 0.5 0.272 14.61 14.61 1.0 1988848 ChemDiv2_007896 Cc1cccc(c1)n2nnc(C(=O)N3CCc4ccccc4C3)c2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G21 compound treatment 0.273 0.0449 2.41 2.4115 1.0 1988849 ChemDiv2_007897 Cc1cc(=O)nc2c3ccccc3n(CC(=O)NCCc4ccccc4)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G22 compound treatment 0.245 0.0169 0.91 0.9068 1.0 1988850 ChemDiv2_007898 CSc1nc2ccccc2c3nc4ccccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G23 mock treatment 0.24 0.0119 0.64 0.6381 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 G24 mock treatment 0.229 8.75E-4 0.05 0.047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H01 compound treatment 0.239 0.0109 0.58 0.5844 1.0 1988851 ChemDiv2_007899 COc1ccc(Cn2c(SCC#N)nc3c4ccccc4sc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H02 compound treatment 0.33 0.102 5.47 5.4745 1.0 1988852 ChemDiv2_007900 CCOc1ccccc1NC(=O)C(CC)Sc2nc3ccccc3c(=O)n2C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H03 compound treatment 0.298 0.0699 3.75 3.7549 1.0 1988853 ChemDiv2_007901 CCOC(=O)CSc1nc2c3ccccc3sc2c(=O)n1CCCOC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H04 compound treatment 0.511 0.283 15.2 15.2011 1.0 1988854 ChemDiv2_007902 CCN(CC)C(=O)CSc1nc2ccccc2c(=O)n1Cc3ccc(cc3)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H05 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1988855 ChemDiv2_007903 COc1ccc2OC3(C)CC(C(C(=O)c4ccccc4)C(=O)N3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H06 compound treatment 0.26 0.0319 1.71 1.7129 1.0 1527468 ChemDiv2_007904 CCOC(=O)CSc1nc2cc(ccc2c(=O)n1c3ccccc3)C(=O)N4CCC(CC4)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H07 compound treatment 0.315 0.0869 4.67 4.6685 1.0 1585113 ChemDiv2_007905 O=C(CSc1nc2ccccc2c(=O)n1Cc3ccc4OCOc4c3)NC5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H08 compound treatment 0.271 0.0429 2.3 2.304 1.0 1988856 ChemDiv2_007906 COC(=O)c1ccccc1NC(=O)CSc2nc3ccsc3c(=O)n2c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H09 compound treatment 0.443 0.215 11.55 11.5469 1.0 1285900 ChemDiv2_007907 CC(C)(C)C(=O)CSc1nc2ccccc2c(=O)n1CCCN3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H10 compound treatment 0.444 0.216 11.6 11.6007 1.0 1327694 ChemDiv2_007908 CCCCn1c(SCC(=O)Nc2ccccc2OC)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H11 compound treatment 0.409 0.181 9.72 9.7198 1.0 1540338 ChemDiv2_007909 COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)Nc4ccc(C)c(Cl)c4)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H12 compound treatment 0.258 0.0299 1.61 1.6054 1.0 1988857 ChemDiv2_007910 Cc1cc(ccc1Cl)n2c(SCC(=O)Nc3nccs3)nc4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H13 compound treatment 0.391 0.163 8.75 8.7526 1.0 1207708 ChemDiv2_007911 CC(=O)NCCn1c(SCC(=O)c2ccccc2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H14 compound treatment 0.448 0.22 11.82 11.8156 1.0 1988858 ChemDiv2_007912 CCC(C)n1c(SCC(=O)Nc2ccc(OC)cc2OC)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H15 compound treatment 0.227 -0.00112 -0.06 -0.0605 -1.0 1524775 ChemDiv2_007913 CC(=O)NCCn1c(SCC(=O)NCC2CCCO2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H16 compound treatment 0.42 0.192 10.31 10.311 1.0 1988859 ChemDiv2_007914 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nc3ccsc3c(=O)n2Cc4ccccn4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H17 compound treatment 0.242 0.0139 0.75 0.7456 1.0 1481512 ChemDiv2_007915 CCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1CC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H18 compound treatment 0.262 0.0339 1.82 1.8204 1.0 1988860 ChemDiv2_007916 CN(C)C(=O)c1sc2n(CC(=O)Nc3cccc(C)c3)c(=O)n(Cc4ccccc4)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H19 compound treatment 0.492 0.264 14.18 14.1801 1.0 1443763 ChemDiv2_007917 Fc1ccccc1CSc2nc3ccccc3c(=O)n2CCCC(=O)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H20 compound treatment 0.222 -0.00612 -0.33 -0.3291 -1.0 1639970 ChemDiv2_007918 O=C1C2C3CC(C=C3)C2C(=O)N1c4nc[nH]n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H21 compound treatment 0.451 0.223 11.98 11.9768 1.0 1988861 ChemDiv2_007919 CCOc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2C4CC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H22 compound treatment 0.267 0.0389 2.09 2.0891 1.0 1988862 ChemDiv2_007920 COC(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H23 mock treatment 0.234 0.00588 0.32 0.3157 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 H24 mock treatment 0.22 -0.00812 -0.44 -0.4366 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I01 compound treatment 0.218 -0.0101 -0.54 -0.5441 -1.0 1988863 ChemDiv2_007921 Cn1c(=O)c(=O)n(C)c2cc(ccc12)S(=O)(=O)CCC(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I02 compound treatment 0.278 0.0499 2.68 2.6802 1.0 1988864 ChemDiv2_007922 CCN(CC)C(=O)CSCc1cnn(c1n2cccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I03 compound treatment 0.464 0.236 12.68 12.6754 1.0 1988865 ChemDiv2_007923 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)N3CCN(CC3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I04 compound treatment 0.56 0.332 17.83 17.8343 1.0 1988866 ChemDiv2_007924 CC(C)NC(=O)c1oc2CCc3cn[nH]c3-c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I05 compound treatment 0.244 0.0159 0.85 0.8531 1.0 1988867 ChemDiv2_007925 CCc1ccc(s1)S(=O)(=O)NCc2csc(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I06 compound treatment 0.31 0.0819 4.4 4.3998 1.0 1988868 ChemDiv2_007926 CN1CCC(=CC1)c2noc(CCC(=O)N3CCN(CC3)c4ccccn4)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I07 compound treatment 0.418 0.19 10.2 10.2035 1.0 1988869 ChemDiv2_007927 Clc1ccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCC4)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I08 compound treatment 0.299 0.0709 3.81 3.8087 1.0 1988870 ChemDiv2_007928 CCOC(=O)N1CCN(CC1)C(=O)c2cc([nH]c2C)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I09 compound treatment 0.256 0.0279 1.5 1.4979 1.0 1988871 ChemDiv2_007929 C=CCN(C(=O)c1ccc2snnc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I10 compound treatment 0.269 0.0409 2.2 2.1965 1.0 1312145 ChemDiv2_007930 CCCCc1noc(n1)c2c(C)onc2c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I11 compound treatment 0.457 0.229 12.3 12.2993 1.0 1988872 ChemDiv2_007931 O=C(NCCc1cc2ccccc2[nH]1)c3ccc4snnc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I12 compound treatment 0.456 0.228 12.25 12.2455 1.0 1607251 ChemDiv2_007932 Clc1ccc2oc(=O)c(cc2c1)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I13 compound treatment 0.303 0.0749 4.02 4.0236 1.0 1193482 ChemDiv2_007933 OC(=O)CCc1nc(no1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I14 compound treatment 0.478 0.25 13.43 13.4278 1.0 1988873 ChemDiv2_007934 O=C(C1CCC(Cn2c(=O)[nH]c3ccccc3c2=O)CC1)N4CCN(CC4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I15 compound treatment 0.233 0.00488 0.26 0.262 1.0 1988874 ChemDiv2_007935 COc1ccc2[nH]c3c(=O)n(Cc4ccc(Cl)cc4)cnc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I16 compound treatment 0.372 0.144 7.73 7.7315 1.0 1988875 ChemDiv2_007936 CN1CCN(CC1)C(=O)c2ccc3c(=O)n(CCC4=CCCCC4)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I17 compound treatment 0.27 0.0419 2.25 2.2503 1.0 1490751 ChemDiv2_007937 COCc1cc(CN2CCN(CC2)c3ccccc3OC)c(O)c4ncccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I18 compound treatment 0.54 0.312 16.76 16.7595 1.0 1988876 ChemDiv2_007938 CCOC(=O)c1sc(=S)n2c1[nH]c(=O)c3ccc(cc32)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I19 compound treatment 0.267 0.0389 2.09 2.0891 1.0 1988877 ChemDiv2_007939 CC(C)N(Cc1ccccc1)C(=O)Cn2nc(C)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I20 compound treatment 0.499 0.271 14.56 14.5563 1.0 1988878 ChemDiv2_007940 c1c(nc2ncccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I21 compound treatment 0.298 0.0699 3.75 3.7549 1.0 1988879 ChemDiv2_007941 Cc1cc(=O)nc2c3ccccc3n(CC(=O)NC4CCCc5ccccc45)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I22 compound treatment 0.513 0.285 15.31 15.3086 1.0 1722522 ChemDiv2_007942 CCc1nc2c(=O)[nH]c3ccccc3c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I23 mock treatment 0.238 0.00987 0.53 0.5307 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 I24 mock treatment 0.228 -1.25E-4 -0.01 -0.0067 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J01 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988880 ChemDiv2_007943 O=C(CSc1nc2c3ccccc3sc2c(=O)n1Cc4ccccc4)NCC5CCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J02 compound treatment 0.374 0.146 7.84 7.839 1.0 1988881 ChemDiv2_007944 CC1CC(C)CN(C1)C(=O)CSc2nc3ccccc3c(=O)n2C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J03 compound treatment 0.289 0.0609 3.27 3.2713 1.0 1988882 ChemDiv2_007945 O=C(CSc1nc2c3ccccc3sc2c(=O)n1CCCN4CCCC4)NCc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J04 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1251713 ChemDiv2_007946 Nc1c(sc(=S)n1CC=C)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J05 compound treatment 0.23 0.00188 0.1 0.1008 1.0 1988883 ChemDiv2_007947 CCC(Sc1nc2ccccc2c3nc(C)nn13)C(=O)Nc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J06 compound treatment 0.385 0.157 8.43 8.4301 1.0 1594666 ChemDiv2_007948 CCOC(=O)CSc1nc2ccsc2c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J07 compound treatment 0.258 0.0299 1.61 1.6054 1.0 1428683 ChemDiv2_007949 O=c1n(C2CCCCC2)c(SCC#N)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J08 compound treatment 0.398 0.17 9.13 9.1287 1.0 1466995 ChemDiv2_007950 Oc1ccc(cc1O)C(=O)CSc2nc3ccsc3c(=O)n2c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J09 compound treatment 0.495 0.267 14.34 14.3413 1.0 1705428 ChemDiv2_007951 Fc1cccc(F)c1CSc2nc3ccccc3c(=O)n2CCCN4CCCC4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J10 compound treatment 0.27 0.0419 2.25 2.2503 1.0 1310323 ChemDiv2_007952 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J11 compound treatment 0.433 0.205 11.01 11.0096 1.0 1297081 ChemDiv2_007953 COc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J12 compound treatment 0.244 0.0159 0.85 0.8531 1.0 1988884 ChemDiv2_007954 CCC(C)n1c(SCc2ccccc2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J13 compound treatment 0.307 0.0789 4.24 4.2386 1.0 1377318 ChemDiv2_007955 NS(=O)(=O)c1ccc(CCNC(=O)CSc2nc3ccccc3c(=O)n2c4ccc5OCOc5c4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J14 compound treatment 0.259 0.0309 1.66 1.6592 1.0 1988885 ChemDiv2_007956 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)NCc3ccco3)nc4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J15 compound treatment 0.22 -0.00812 -0.44 -0.4366 -1.0 1597062 ChemDiv2_007957 CCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1CCNC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J16 compound treatment 0.461 0.233 12.51 12.5142 1.0 1988886 ChemDiv2_007958 Cc1ccc(CSc2nc3ccsc3c(=O)n2Cc4ccccn4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J17 compound treatment 0.248 0.0199 1.07 1.068 1.0 1742974 ChemDiv2_007959 O=C(CSc1nc2ccccc2c(=O)n1CC3CCCO3)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J18 compound treatment 0.394 0.166 8.91 8.9138 1.0 1585416 ChemDiv2_007960 CC(C)N1CCc2c(C(=O)N)c(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J19 compound treatment 0.245 0.0169 0.91 0.9068 1.0 1564104 ChemDiv2_007961 O=C(CSc1nc2ccccc2c(=O)n1CCCN3CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J20 compound treatment 0.292 0.0639 3.43 3.4325 1.0 1170378 ChemDiv2_007962 CN(Cc1ccccc1)C(=O)c2cccc(c2)N3C(=O)C4CC=CCC4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J21 compound treatment 0.356 0.128 6.87 6.8717 1.0 1988887 ChemDiv2_007963 Fc1cccc(CSc2nc3cc4OCOc4cc3c(=O)n2Cc5ccco5)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J22 compound treatment 0.247 0.0189 1.01 1.0143 1.0 1988888 ChemDiv2_007964 CCc1ccc(cc1)c2nc(CN3CCC(CC3)C(=O)O)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J23 mock treatment 0.23 0.00188 0.1 0.1008 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 J24 mock treatment 0.217 -0.0111 -0.6 -0.5978 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K01 compound treatment 0.235 0.00687 0.37 0.3694 1.0 1988889 ChemDiv2_007965 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K02 compound treatment 0.385 0.157 8.43 8.4301 1.0 1988890 ChemDiv2_007966 O=C(CSCc1cnn(c1n2cccc2)c3ccccc3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K03 compound treatment 0.429 0.201 10.79 10.7946 1.0 1988891 ChemDiv2_007967 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)N3CCC(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K04 compound treatment 0.247 0.0189 1.01 1.0143 1.0 1988892 ChemDiv2_007968 CCOC(=O)N1CCC(CC1)NC(=O)c2sc3nc(C)cc(C)c3c2n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K05 compound treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1988893 ChemDiv2_007969 Cc1nc(CNS(=O)(=O)c2cccc(C)c2)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K06 compound treatment 0.366 0.138 7.41 7.4091 1.0 1988894 ChemDiv2_007970 CCc1nnc(NC(=O)CCc2nc(no2)C3=CCN(C)CC3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K07 compound treatment 0.38 0.152 8.16 8.1614 1.0 1988895 ChemDiv2_007971 O=C(Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCCC3)NCc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K08 compound treatment 0.277 0.0489 2.63 2.6264 1.0 1988896 ChemDiv2_007972 CCOC(=O)N1CCC(CC1)NC(=O)c2cc([nH]c2C)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K09 compound treatment 0.253 0.0249 1.34 1.3367 1.0 1988897 ChemDiv2_007973 COc1ccc(cc1)N(C)C(=O)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K10 compound treatment 0.493 0.265 14.23 14.2338 1.0 1696513 ChemDiv2_007974 CCCCc1ccc(cc1)c2nc(no2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K11 compound treatment 0.467 0.239 12.84 12.8366 1.0 1988898 ChemDiv2_007975 COc1ccc(OCCNC(=O)c2ccc3snnc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K12 compound treatment 0.463 0.235 12.62 12.6217 1.0 1988899 ChemDiv2_007976 O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K13 compound treatment 0.307 0.0789 4.24 4.2386 1.0 1988900 ChemDiv2_007977 OC(=O)c1ccccc1c2nc(no2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K14 compound treatment 0.481 0.253 13.59 13.589 1.0 1988901 ChemDiv2_007978 O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)N(Cc3ccccc3)Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K15 compound treatment 0.304 0.0759 4.08 4.0774 1.0 1988902 ChemDiv2_007979 Fc1ccc2[nH]c3c(=O)n(CCN4CCN(Cc5ccccc5)CC4)cnc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K16 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988903 ChemDiv2_007980 CCC(C)NC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K17 compound treatment 0.516 0.288 15.47 15.4698 1.0 1988904 ChemDiv2_007981 Oc1nc(nc2n(Cc3ccco3)nnc12)C4CCN(CC4)C(=O)c5ccccc5Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K18 compound treatment 0.393 0.165 8.86 8.86 1.0 1988905 ChemDiv2_007982 O=C(NCc1ccccc1)c2sc(=S)n3c2[nH]c(=O)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K19 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1988906 ChemDiv2_007983 Cc1nn(CC(=O)NC2CCCCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K20 compound treatment 0.233 0.00488 0.26 0.262 1.0 1988907 ChemDiv2_007984 CCN(CC)CCCNC1=NC2CS(=O)(=O)CC2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K21 compound treatment 0.238 0.00987 0.53 0.5307 1.0 1988908 ChemDiv2_007985 CNC(=O)Cn1c2ccccc2c3nc(=O)cc(C)n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K22 compound treatment 0.521 0.293 15.74 15.7385 1.0 1538853 ChemDiv2_007986 CCCCc1nc2c(=O)[nH]c3ccccc3c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K23 mock treatment 0.234 0.00588 0.32 0.3157 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 K24 mock treatment 0.233 0.00488 0.26 0.262 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L01 compound treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1988909 ChemDiv2_007987 CCN(CC)CCn1c(SCC(=O)NCc2ccccc2)nc3c4ccccc4sc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L02 compound treatment 0.265 0.0369 1.98 1.9816 1.0 1988910 ChemDiv2_007988 COc1ccc(Cn2c(SCC(=O)c3ccccc3)nc4ccc(cc4c2=O)N5CCOCC5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L03 compound treatment 0.344 0.116 6.23 6.2269 1.0 1988911 ChemDiv2_007989 NC(=O)CSc1nc2c3ccccc3sc2c(=O)n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L04 compound treatment 0.248 0.0199 1.07 1.068 1.0 1401980 ChemDiv2_007990 Nc1c(sc(=S)n1c2ccccc2)C(=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L05 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1988912 ChemDiv2_007991 CCC(Sc1nc2ccccc2c3nc(CCn4cncc4C)nn13)C(=O)NC5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L06 compound treatment 0.272 0.0439 2.36 2.3578 1.0 1363943 ChemDiv2_007992 CC(C)(C)C(=O)CSc1nc2ccsc2c(=O)n1Cc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L07 compound treatment 0.238 0.00987 0.53 0.5307 1.0 1376230 ChemDiv2_007993 O=C(CSc1nc2ccccc2c(=O)n1CCc3ccccc3)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L08 compound treatment 0.451 0.223 11.98 11.9768 1.0 1219925 ChemDiv2_007994 CCOC(=O)c1ccc(NC(=O)CSc2nc3ccsc3c(=O)n2Cc4ccc5OCOc5c4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L09 compound treatment 0.243 0.0149 0.8 0.7994 1.0 1120565 ChemDiv2_007995 COC(=O)c1ccc2c(=O)n(CCN3CCOCC3)c(SCC(=O)c4ccccc4)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L10 compound treatment 0.536 0.308 16.54 16.5446 1.0 1269074 ChemDiv2_007996 CCCCn1c(SCC(=O)c2ccc(O)c(O)c2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L11 compound treatment 0.26 0.0319 1.71 1.7129 1.0 1494178 ChemDiv2_007997 Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc4ccccc4)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L12 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1988913 ChemDiv2_007998 CCC(C)n1c(SCC(=O)NCCc2ccc(OC)c(OC)c2)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L13 compound treatment 0.264 0.0359 1.93 1.9278 1.0 1199322 ChemDiv2_007999 CCOC(=O)CSc1nc2ccccc2c(=O)n1C3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L14 compound treatment 0.53 0.302 16.22 16.2221 1.0 1988914 ChemDiv2_008000 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)Nc3ccc(OC)cc3OC)nc4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L15 compound treatment 0.241 0.0129 0.69 0.6919 1.0 1369130 ChemDiv2_008001 CCN(CC)C(=O)CSc1nc2ccccc2c(=O)n1CCc3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L16 compound treatment 0.35 0.122 6.55 6.5493 1.0 1988915 ChemDiv2_008002 CCOc1ccccc1NC(=O)C(CC)Sc2nc3ccsc3c(=O)n2Cc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L17 compound treatment 0.26 0.0319 1.71 1.7129 1.0 1499890 ChemDiv2_008003 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)N3CCCCCC3)nc4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L18 compound treatment 0.547 0.319 17.14 17.1357 1.0 1181250 ChemDiv2_008004 COC(=O)c1c(NC(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3)sc4CN(CCc14)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L19 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1469092 ChemDiv2_008005 CCC(Sc1nc2ccccc2c(=O)n1C3CCCC3)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L20 compound treatment 0.242 0.0139 0.75 0.7456 1.0 1570756 ChemDiv2_008006 O=S(=O)(N1CCCC1)c2cccc3nsnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L21 compound treatment 0.233 0.00488 0.26 0.262 1.0 1988916 ChemDiv2_008007 COc1ccc(CCNC(=O)CSc2nc3cc4OCOc4cc3c(=O)n2Cc5ccco5)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L22 compound treatment 0.401 0.173 9.29 9.2899 1.0 1988917 ChemDiv2_008008 COC(=O)c1ccc2c(c1)N(Cc3ccc(Cl)cc3)C(=O)c4ccccc4S2(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L23 mock treatment 0.234 0.00588 0.32 0.3157 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 L24 mock treatment 0.219 -0.00912 -0.49 -0.4904 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M01 compound treatment 0.435 0.207 11.12 11.117 1.0 1988918 ChemDiv2_008009 Cc1cc(NC(=O)CNS(=O)(=O)c2ccc3nc(C)sc3c2)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M02 compound treatment 0.244 0.0159 0.85 0.8531 1.0 1988919 ChemDiv2_008010 CCOC(=O)N1CCC(CC1)NC(=O)CSCc2cnn(c2n3cccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M03 compound treatment 0.311 0.0829 4.45 4.4535 1.0 1988920 ChemDiv2_008011 CC1CCC(CC1)NC(=O)CNS(=O)(=O)c2ccc3nc(C)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M04 compound treatment 0.465 0.237 12.73 12.7292 1.0 1988921 ChemDiv2_008012 COc1ccc(cc1)c2cc3c(=O)n(CC(=O)NCc4cccc(Br)c4)ncn3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M05 compound treatment 0.313 0.0849 4.56 4.561 1.0 1988922 ChemDiv2_008013 Clc1ccc(cc1)S(=O)(=O)NCc2csc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M06 compound treatment 0.308 0.0799 4.29 4.2923 1.0 1988923 ChemDiv2_008014 CCN1CCN(Cc2ccc(NC(=O)CCc3nc(no3)C4=CCN(C)CC4)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M07 compound treatment 0.397 0.169 9.07 9.075 1.0 1988924 ChemDiv2_008015 COc1cccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M08 compound treatment 0.256 0.0279 1.5 1.4979 1.0 1988925 ChemDiv2_008016 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc3N(C)C(=O)C(C)(C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M09 compound treatment 0.324 0.0959 5.15 5.1521 1.0 1988926 ChemDiv2_008017 OCCNC(=O)c1ccc2snnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M10 compound treatment 0.273 0.0449 2.41 2.4115 1.0 1988927 ChemDiv2_008018 Cc1ccc(cc1)c2noc(n2)c3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M11 compound treatment 0.444 0.216 11.6 11.6007 1.0 1988928 ChemDiv2_008019 O=C(Nc1ccccc1)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M12 compound treatment 0.265 0.0369 1.98 1.9816 1.0 1988929 ChemDiv2_008020 O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M13 compound treatment 0.28 0.0519 2.79 2.7877 1.0 1988930 ChemDiv2_008021 OC(=O)CC1(Cc2nc(no2)c3cccs3)CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M14 compound treatment 0.267 0.0389 2.09 2.0891 1.0 1988931 ChemDiv2_008022 O=C(Cc1ccc(cc1)n2c(=O)[nH]c3ccccc3c2=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M15 compound treatment 0.249 0.0209 1.12 1.1218 1.0 1627118 ChemDiv2_008023 Cn1c(NCc2cccs2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M16 compound treatment 0.266 0.0379 2.04 2.0353 1.0 1988932 ChemDiv2_008024 Cc1ncc(CO)c2cc(C(=O)Nc3ccccc3Cl)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M17 compound treatment 0.348 0.12 6.44 6.4418 1.0 1988933 ChemDiv2_008025 Cc1ccc(C)c(c1)S(=O)(=O)N2CCC(CC2)c3nc(O)c4nnn(Cc5ccc(F)cc5)c4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M18 compound treatment 0.311 0.0829 4.45 4.4535 1.0 1988934 ChemDiv2_008026 O=C(NC1CCCC1)c2sc(=S)n3c2[nH]c(=O)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M19 compound treatment 0.457 0.229 12.3 12.2993 1.0 1988935 ChemDiv2_008027 CN(Cc1ccccc1)C(=O)Cn2c3ccccc3c4nc(=O)cc(C)n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M20 compound treatment 0.272 0.0439 2.36 2.3578 1.0 1988936 ChemDiv2_008028 CCCCN(C)C(=O)c1ccc(Cl)c(NC2=NC3CS(=O)(=O)CC3S2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M21 compound treatment 0.267 0.0389 2.09 2.0891 1.0 1988937 ChemDiv2_008029 CC(NC(=O)Cn1c2ccccc2c3nc(=O)cc(C)n13)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M22 compound treatment 0.493 0.265 14.23 14.2338 1.0 1381416 ChemDiv2_008030 CCCc1nc2c(=O)[nH]c3ccccc3c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M23 mock treatment 0.234 0.00588 0.32 0.3157 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 M24 mock treatment 0.227 -0.00112 -0.06 -0.0605 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N01 compound treatment 0.236 0.00787 0.42 0.4232 1.0 1988938 ChemDiv2_008031 NC(=O)CSc1nc2c3ccccc3sc2c(=O)n1CCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N02 compound treatment 0.276 0.0479 2.57 2.5727 1.0 1988939 ChemDiv2_008032 CCN(CC)C(=O)CSc1nc2ccc(cc2c(=O)n1Cc3ccc4OCOc4c3)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N03 compound treatment 0.262 0.0339 1.82 1.8204 1.0 1988940 ChemDiv2_008033 OCCn1c(SCC#N)nc2c3ccccc3sc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N04 compound treatment 0.242 0.0139 0.75 0.7456 1.0 1988941 ChemDiv2_008034 COC(=O)c1sc(=S)n(c1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N05 compound treatment 0.237 0.00887 0.48 0.4769 1.0 1988942 ChemDiv2_008035 Cc1nc2c3ccccc3nc(SCc4ccc(C#N)cc4)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N06 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1174827 ChemDiv2_008036 O=C(CSc1nc2ccsc2c(=O)n1Cc3ccccc3)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N07 compound treatment 0.242 0.0139 0.75 0.7456 1.0 1362932 ChemDiv2_008037 O=c1n(Cc2ccccc2)c(SCC#N)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N08 compound treatment 0.255 0.0269 1.44 1.4442 1.0 1988943 ChemDiv2_008038 O=C(CSc1nc2ccsc2c(=O)n1CCc3ccccc3)Nc4nccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N09 compound treatment 0.234 0.00588 0.32 0.3157 1.0 1681699 ChemDiv2_008039 CCN(C(=O)CSc1nc2ccccc2c(=O)n1CC3CCCO3)c4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N10 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988944 ChemDiv2_008040 CCCCn1c(SCC(=O)Nc2ccccc2C(=O)OC)nc3ccsc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N11 compound treatment 0.358 0.13 6.98 6.9792 1.0 1701634 ChemDiv2_008041 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CC4COc5ccccc5O4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N12 compound treatment 0.265 0.0369 1.98 1.9816 1.0 1988945 ChemDiv2_008042 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)Nc3ccccc3C(=O)OC)nc4ccsc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N13 compound treatment 0.322 0.0939 5.04 5.0446 1.0 1393424 ChemDiv2_008043 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2C4CCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N14 compound treatment 0.412 0.184 9.88 9.8811 1.0 1988946 ChemDiv2_008044 O=C(CSc1nc2ccsc2c(=O)n1C3CC3)OCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N15 compound treatment 0.253 0.0249 1.34 1.3367 1.0 1257980 ChemDiv2_008045 CC(=O)NCCn1c(SCC(=O)OCc2ccccc2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N16 compound treatment 0.226 -0.00212 -0.11 -0.1142 -1.0 1988947 ChemDiv2_008046 COc1cccc(c1)n2c(=O)n(Cc3ccccc3)c4sc(C(=O)N(C)C)c(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N17 compound treatment 0.244 0.0159 0.85 0.8531 1.0 1579071 ChemDiv2_008047 O=C(CCCn1c(SCC(=O)c2ccccc2)nc3ccccc3c1=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N18 compound treatment 0.503 0.275 14.77 14.7712 1.0 1332490 ChemDiv2_008048 CCOC(=O)N1CCc2c(C(=O)N)c(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC)CC)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N19 compound treatment 0.25 0.0219 1.18 1.1755 1.0 1397320 ChemDiv2_008049 CCC(Sc1nc2ccccc2c(=O)n1Cc3ccccc3OC)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N20 compound treatment 0.233 0.00488 0.26 0.262 1.0 1393210 ChemDiv2_008050 O=C(CCS(=O)(=O)c1ccccc1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N21 compound treatment 0.212 -0.0161 -0.87 -0.8665 -1.0 1988948 ChemDiv2_008051 CCC(Sc1nc2cc3OCOc3cc2c(=O)n1Cc4ccco4)C(=O)Nc5ccccc5CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N22 compound treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1988949 ChemDiv2_008052 COC(=O)c1ccc2S(=O)c3ccccc3C(=O)N(Cc4cc(C)ccc4C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N23 mock treatment 0.231 0.00288 0.15 0.1545 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 N24 mock treatment 0.21 -0.0181 -0.97 -0.974 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O01 compound treatment 0.281 0.0529 2.84 2.8414 1.0 1988950 ChemDiv2_008053 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)NCc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O02 compound treatment 0.326 0.0979 5.26 5.2596 1.0 1988951 ChemDiv2_008054 O=C(CSCc1cnn(c1n2cccc2)c3ccccc3)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O03 compound treatment 0.267 0.0389 2.09 2.0891 1.0 1988952 ChemDiv2_008055 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O04 compound treatment 0.332 0.104 5.58 5.582 1.0 1988953 ChemDiv2_008056 O=C(C1CCN(CC1)c2nnc(s2)N3CCCC3=O)N4CCN(CC4)C5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O05 compound treatment 0.265 0.0369 1.98 1.9816 1.0 1988954 ChemDiv2_008057 CCOc1ccc(cc1)S(=O)(=O)NCc2csc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O06 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988955 ChemDiv2_008058 CCOC(=O)c1[nH]c(C)c(C(=O)N2CCc3ccccc23)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O07 compound treatment 0.352 0.124 6.66 6.6568 1.0 1988956 ChemDiv2_008059 CN(Cc1ccccc1)C(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O08 compound treatment 0.264 0.0359 1.93 1.9278 1.0 1988957 ChemDiv2_008060 COc1ccc(cc1)c2noc(n2)N3CCC(CC3)C(=O)N4CCN(CC4)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O09 compound treatment 0.259 0.0309 1.66 1.6592 1.0 1988958 ChemDiv2_008061 COc1ccc(OC)c(NC(=O)c2ccc3snnc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O10 compound treatment 0.237 0.00887 0.48 0.4769 1.0 1927690 ChemDiv2_008062 Cc1ccc(cc1)c2noc(n2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O11 compound treatment 0.236 0.00787 0.42 0.4232 1.0 1988959 ChemDiv2_008063 NC(=O)C1CCC(CC1)NC(=O)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O12 compound treatment 0.262 0.0339 1.82 1.8204 1.0 1374592 ChemDiv2_008064 O=c1[nH]c2ccccc2c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O13 compound treatment 0.232 0.00388 0.21 0.2082 1.0 1988960 ChemDiv2_008065 CC1CCCCN1CCn2cnc3c4ccccc4[nH]c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O14 compound treatment 0.291 0.0629 3.38 3.3788 1.0 1988961 ChemDiv2_008066 CCC1CCCCN1CCCNC(=O)C2CCC(Cn3c(=O)[nH]c4ccccc4c3=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O15 compound treatment 0.253 0.0249 1.34 1.3367 1.0 1988962 ChemDiv2_008067 CCn1c(NCc2ccco2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O16 compound treatment 0.474 0.246 13.21 13.2128 1.0 1988963 ChemDiv2_008068 Cc1ncc(CO)c2cc(c3nnc(NCc4ccco4)s3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O17 compound treatment 0.247 0.0189 1.01 1.0143 1.0 1988964 ChemDiv2_008069 OC(C(CN1CCOCC1)c2ccccc2)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O18 compound treatment 0.252 0.0239 1.28 1.283 1.0 1988965 ChemDiv2_008070 O=C(N1CCc2ccccc2C1)c3sc(=S)n4c3[nH]c(=O)c5ccccc54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O19 compound treatment 0.244 0.0159 0.85 0.8531 1.0 1988966 ChemDiv2_008071 CCCN(CCC)C(=O)Cn1c2ccccc2c3nc(=O)cc(C)n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O20 compound treatment 0.266 0.0379 2.04 2.0353 1.0 1988967 ChemDiv2_008072 Clc1ccc(cc1NC2=NC3CS(=O)(=O)CC3S2)C(=O)NC4CCCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O21 compound treatment 0.24 0.0119 0.64 0.6381 1.0 1988968 ChemDiv2_008073 CC(C(=O)N1CCc2ccccc12)n3c4ccccc4c5nc(=O)cc(C)n35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O22 compound treatment 0.499 0.271 14.56 14.5563 1.0 1988969 ChemDiv2_008074 CC(=O)N1CCc2c(C1)sc3nc([nH]c(=O)c23)c4cc5cc(Cl)ccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O23 mock treatment 0.235 0.00687 0.37 0.3694 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 O24 mock treatment 0.226 -0.00212 -0.11 -0.1142 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P01 compound treatment 0.237 0.00887 0.48 0.4769 1.0 1988970 ChemDiv2_008075 COc1ccc(CCn2c(SCC(=O)N)nc3c4ccccc4sc3c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P02 compound treatment 0.283 0.0549 2.95 2.9489 1.0 1988971 ChemDiv2_008076 COc1ccc(CCn2c(SCC#N)nc3ccc(cc3c2=O)N4CCOCC4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P03 compound treatment 0.254 0.0259 1.39 1.3905 1.0 1988972 ChemDiv2_008077 COc1cccc(NC(=O)CSc2nc3c4ccccc4sc3c(=O)n2CCN(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P04 compound treatment 0.26 0.0319 1.71 1.7129 1.0 1988973 ChemDiv2_008078 CCOC(=O)Cn1c(N)c(sc1=S)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P05 compound treatment 0.229 8.75E-4 0.05 0.047 1.0 1988974 ChemDiv2_008079 Cc1n[nH]c(C)c1CCc2nc3c4ccccc4nc(SCC#N)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P06 compound treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1420544 ChemDiv2_008080 CCC(C)NC(=O)CSc1nc2ccsc2c(=O)n1CCc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P07 compound treatment 0.232 0.00388 0.21 0.2082 1.0 1988975 ChemDiv2_008081 O=C(CSc1nc2ccccc2c(=O)n1Cc3ccco3)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P08 compound treatment 0.219 -0.00912 -0.49 -0.4904 -1.0 1686622 ChemDiv2_008082 COc1ccc(CCn2c(SCC(=O)NC3CCCCC3)nc4ccsc4c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P09 compound treatment 0.238 0.00987 0.53 0.5307 1.0 1988976 ChemDiv2_008083 Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc4ccco4)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P10 compound treatment 0.217 -0.0111 -0.6 -0.5978 -1.0 1621666 ChemDiv2_008084 CCCCn1c(SC(CC)C(=O)Nc2ccc3OCOc3c2)nc4ccsc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P11 compound treatment 0.228 -1.25E-4 -0.01 -0.0067 -1.0 1517332 ChemDiv2_008085 O=C(CSc1nc2ccccc2c(=O)n1CC3COc4ccccc4O3)NCc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P12 compound treatment 0.282 0.0539 2.9 2.8951 1.0 1988977 ChemDiv2_008086 Oc1ccc2c(CSc3nc4ccsc4c(=O)n3CCCC(=O)NCCc5ccccc5)cc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P13 compound treatment 0.22 -0.00812 -0.44 -0.4366 -1.0 1566949 ChemDiv2_008087 CCOC(=O)N1CCC(CC1)n2c(SCC(=O)c3ccc(Cl)cc3)nc4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P14 compound treatment 0.224 -0.00412 -0.22 -0.2217 -1.0 1988978 ChemDiv2_008088 CCC(Sc1nc2ccsc2c(=O)n1C3CC3)C(=O)Nc4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P15 compound treatment 0.227 -0.00112 -0.06 -0.0605 -1.0 1601321 ChemDiv2_008089 CCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1CC3COc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P16 compound treatment 0.216 -0.0121 -0.65 -0.6516 -1.0 1988979 ChemDiv2_008090 CCc1ccc(cc1)n2c(=O)n(CC(=O)NCc3ccco3)c4sc(C(=O)N(C)C)c(C)c4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P17 compound treatment 0.23 0.00188 0.1 0.1008 1.0 1485241 ChemDiv2_008091 O=C(CSc1nc2ccccc2c(=O)n1CCCN3CCCCC3)NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P18 compound treatment 0.368 0.14 7.52 7.5166 1.0 1988980 ChemDiv2_008092 CC(C)SC1=NN2CCCC(=O)N=C2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P19 compound treatment 0.223 -0.00512 -0.28 -0.2754 -1.0 1187309 ChemDiv2_008093 O=C(NCCc1ccccc1)C2CCC(Cn3c(SCC#N)nc4ccccc4c3=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P20 compound treatment 0.218 -0.0101 -0.54 -0.5441 -1.0 1207388 ChemDiv2_008094 O=C(Cn1cnc2sc3CCCc3c2c1=O)Nc4ccc(Oc5ccccc5)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P21 compound treatment 0.219 -0.00912 -0.49 -0.4904 -1.0 1988981 ChemDiv2_008095 CC(C)CSc1nc2cc3OCOc3cc2c(=O)n1Cc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P22 compound treatment 0.246 0.0179 0.96 0.9606 1.0 1988982 ChemDiv2_008096 COC(=O)c1ccc2SCCN(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P23 mock treatment 0.221 -0.00712 -0.38 -0.3829 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1391 P24 mock treatment 0.227 -0.00112 -0.06 -0.0605 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A01 compound treatment 0.317 0.0836 4.49 4.4938 1.0 1988983 ChemDiv2_008097 COC(=O)CSCc1nc2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A02 compound treatment 0.225 -0.00837 -0.45 -0.4501 -1.0 1988984 ChemDiv2_008098 Cc1ccccc1Cc2c(C)nc3c(cnn3c2C)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A03 compound treatment 0.293 0.0596 3.2 3.2041 1.0 1213157 ChemDiv2_008099 CCN(CC)S(=O)(=O)c1ccc2[nH]c3nc(SCC(=O)Nc4ccc(C)c(Cl)c4)nnc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A04 compound treatment 0.271 0.0376 2.02 2.0219 1.0 1988985 ChemDiv2_008100 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NCC2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A05 compound treatment 0.218 -0.0154 -0.83 -0.8262 -1.0 1988986 ChemDiv2_008101 OC(=O)CN1C(=O)C2(OCCCO2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A06 compound treatment 0.247 0.0136 0.73 0.7322 1.0 1988987 ChemDiv2_008102 CCC(Sc1ncccc1C(=O)O)C(=O)Nc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A07 compound treatment 0.299 0.0656 3.53 3.5266 1.0 1988988 ChemDiv2_008103 O=C(NCc1ccccc1)c2ccc(cc2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A08 compound treatment 0.477 0.244 13.09 13.0919 1.0 1988989 ChemDiv2_008104 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)Nc3cccc(OC)c3)c(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A09 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1988990 ChemDiv2_008105 COc1ccc(CCNC(=O)CN2CCOc3ccccc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A10 compound treatment 0.25 0.0166 0.89 0.8934 1.0 1988991 ChemDiv2_008106 Cn1cc(CCC(=O)NCc2ccccc2Cl)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A11 compound treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1988992 ChemDiv2_008107 Cc1cc(C)c2c(=O)n(CC(=O)Nc3ccc(F)cc3C)sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A12 compound treatment 0.215 -0.0184 -0.99 -0.9874 -1.0 1988993 ChemDiv2_008108 CC(C)N1C(CCC1=O)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A13 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1988994 ChemDiv2_008109 OC(=O)CN(Cc1ccccc1)S(=O)(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A14 compound treatment 0.239 0.00562 0.3 0.3023 1.0 1988995 ChemDiv2_008110 CC(=O)Nc1cc(ccc1Sc2ccc(Cl)cc2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A15 compound treatment 0.252 0.0186 1.0 1.0009 1.0 1988996 ChemDiv2_008111 Cc1c2CCCCc2nc3c(cnn13)C(=O)NC4CCCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A16 compound treatment 0.294 0.0606 3.26 3.2579 1.0 1988997 ChemDiv2_008112 Cn1cc(CCCC(=O)NCc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A17 compound treatment 0.375 0.142 7.61 7.6106 1.0 1640090 ChemDiv2_008113 Cc1cc(=O)oc(C)c1C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A18 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1988998 ChemDiv2_008114 CCCCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)cc(C(=O)NCc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A19 compound treatment 0.536 0.303 16.26 16.2624 1.0 1988999 ChemDiv2_008115 O=C(NCCN1CCOCC1)c2ccc3Sc4ccccc4C(=O)N(Cc5ccccc5)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A20 compound treatment 0.508 0.275 14.76 14.7578 1.0 1989000 ChemDiv2_008116 CCOc1ccccc1CNC(=O)c2ccc3n(cnc3c2)C4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A21 compound treatment 0.248 0.0146 0.79 0.7859 1.0 1989001 ChemDiv2_008117 Fc1ccc(CN2C(=O)C3(OCCCO3)c4ccccc24)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A22 compound treatment 0.253 0.0196 1.05 1.0546 1.0 1989002 ChemDiv2_008118 CS(=O)(=O)N1CCC(CC1)C(=O)NCCN2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A23 mock treatment 0.238 0.00462 0.25 0.2485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 A24 mock treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B01 compound treatment 0.222 -0.0114 -0.61 -0.6113 -1.0 1989003 ChemDiv2_008119 O=C(Cn1nc(ccc1=O)c2ccccc2)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B02 compound treatment 0.268 0.0346 1.86 1.8607 1.0 1989004 ChemDiv2_008120 CNC(=O)c1cc(Sc2nnc(C)s2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B03 compound treatment 0.231 -0.00237 -0.13 -0.1276 -1.0 1989005 ChemDiv2_008121 CC(N1CC(CC1=O)C(=O)NC2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B04 compound treatment 0.397 0.164 8.79 8.7929 1.0 1989006 ChemDiv2_008122 CN1CCN(CC1)C(=O)CC2Sc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B05 compound treatment 0.218 -0.0154 -0.83 -0.8262 -1.0 1989007 ChemDiv2_008123 C=CCNC(=O)C1CCC(=O)N1C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B06 compound treatment 0.27 0.0366 1.97 1.9682 1.0 1989008 ChemDiv2_008124 CC(NC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B07 compound treatment 0.256 0.0226 1.22 1.2158 1.0 1989009 ChemDiv2_008125 COc1ccccc1CN2CC(CC2=O)C(=O)NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B08 compound treatment 0.261 0.0276 1.48 1.4845 1.0 1989010 ChemDiv2_008126 O=C(NCCCN1CCCC1)c2ccc(cc2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B09 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989011 ChemDiv2_008127 Cc1ccc(CNC(=O)C2CCC(=O)N2C3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B10 compound treatment 0.442 0.209 11.21 11.2111 1.0 1989012 ChemDiv2_008128 Fc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NC3CCCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B11 compound treatment 0.327 0.0936 5.03 5.0312 1.0 1989013 ChemDiv2_008129 Cc1ccc(cc1)c2ccc(=O)n(CC(=O)NCc3ccco3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B12 compound treatment 0.221 -0.0124 -0.67 -0.665 -1.0 1989014 ChemDiv2_008130 COc1ccccc1S(=O)(=O)Cc2ccc(o2)C(=O)NCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B13 compound treatment 0.309 0.0756 4.06 4.0639 1.0 1989015 ChemDiv2_008131 Cc1cccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCCCN3CCOCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B14 compound treatment 0.317 0.0836 4.49 4.4938 1.0 1989016 ChemDiv2_008132 COc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NC3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B15 compound treatment 0.223 -0.0104 -0.56 -0.5575 -1.0 1989017 ChemDiv2_008133 O=C(NCCc1ccccc1)C2CCC(=O)N2CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B16 compound treatment 0.494 0.261 14.01 14.0054 1.0 1989018 ChemDiv2_008134 CCOc1ccc(cc1)c2nc(CSCC(=O)NC3CC3)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B17 compound treatment 0.475 0.242 12.98 12.9844 1.0 1989019 ChemDiv2_008135 O=C(NCCN1CCCC1)c2ccc3n(cnc3c2)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B18 compound treatment 0.341 0.108 5.78 5.7835 1.0 1546650 ChemDiv2_008136 COc1ccccc1NC(=O)c2sc3ncn(Cc4cccc(F)c4)c(=O)c3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B19 compound treatment 0.259 0.0256 1.38 1.377 1.0 1989020 ChemDiv2_008137 CC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B20 compound treatment 0.464 0.231 12.39 12.3933 1.0 1989021 ChemDiv2_008138 CC1CC(C)CN(C1)S(=O)(=O)c2ccc3[nH]cc(C(=O)O)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B21 compound treatment 0.251 0.0176 0.95 0.9471 1.0 1989022 ChemDiv2_008139 CCCS(=O)(=O)N1CCCC(C1)C(=O)NCCCN2CCN(CC2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B22 compound treatment 0.265 0.0316 1.7 1.6995 1.0 1642991 ChemDiv2_008140 COc1ccc(cc1)C2=CC(c3sccc3C)n4nnnc4N2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B23 mock treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 B24 mock treatment 0.221 -0.0124 -0.67 -0.665 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C01 compound treatment 0.336 0.103 5.51 5.5149 1.0 1989023 ChemDiv2_008141 OC(=O)CSCc1nc2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C02 compound treatment 0.46 0.227 12.18 12.1784 1.0 1989024 ChemDiv2_008142 Cc1c(oc2ccc(cc12)S(=O)(=O)NCc3ccccc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C03 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989025 ChemDiv2_008143 CCOC(=O)c1cn[nH]c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C04 compound treatment 0.331 0.0976 5.25 5.2462 1.0 1989026 ChemDiv2_008144 O=C(NCCC1=CCCCC1)C2CCN(CC2)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C05 compound treatment 0.454 0.221 11.86 11.8559 1.0 1989027 ChemDiv2_008145 CCOC(=O)c1sc2ccc(cc2c1N)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C06 compound treatment 0.33 0.0966 5.19 5.1924 1.0 1989028 ChemDiv2_008146 CC(C)NC(=O)C1CCN(CC1)c2nc3cc(Cl)ccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C07 compound treatment 0.325 0.0916 4.92 4.9237 1.0 1989029 ChemDiv2_008147 O=C(NC1CCCCCCC1)c2ccc(cc2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C08 compound treatment 0.42 0.187 10.03 10.0288 1.0 1989030 ChemDiv2_008148 Cc1c(oc2ccc(cc12)S(=O)(=O)N3CCCCC3)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C09 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989031 ChemDiv2_008149 Cc1cc(C(=O)NCc2ccc(C)cc2)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C10 compound treatment 0.444 0.211 11.32 11.3185 1.0 1989032 ChemDiv2_008150 Cc1ccc(CCNC(=O)C2CCN(CC2)S(=O)(=O)N3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C11 compound treatment 0.222 -0.0114 -0.61 -0.6113 -1.0 1989033 ChemDiv2_008151 COc1ccc(CNC(=O)C2CSC(N2C(=O)C)c3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C12 compound treatment 0.212 -0.0214 -1.15 -1.1486 -1.0 1989034 ChemDiv2_008152 CC(C)N1C(CCC1=O)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C13 compound treatment 0.496 0.263 14.11 14.1129 1.0 1989035 ChemDiv2_008153 COc1ccccc1CNC(=O)c2ccc3nc4[nH]c5ccccc5c4nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C14 compound treatment 0.316 0.0826 4.44 4.4401 1.0 1989036 ChemDiv2_008154 CN(CCC#N)C(=O)c1ccc(Sc2ccc(Cl)cc2)c(NC(=O)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C15 compound treatment 0.406 0.173 9.28 9.2765 1.0 1989037 ChemDiv2_008155 COc1cccc(CNC(=O)c2cnn3c(C)c4CCCCc4nc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C16 compound treatment 0.431 0.198 10.62 10.62 1.0 1989038 ChemDiv2_008156 Clc1ccccc1OC(=O)c2cccnc2SCC(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C17 compound treatment 0.265 0.0316 1.7 1.6995 1.0 1989039 ChemDiv2_008157 CCc1nc2ccc(cc2nc1CC)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C18 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989040 ChemDiv2_008158 Cc1ccc(cc1)S(=O)(=O)N(CCCN2CCOCC2)Cc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C19 compound treatment 0.312 0.0786 4.23 4.2251 1.0 1989041 ChemDiv2_008159 C=CCN1C(=O)CSc2ccc(cc12)C(=O)N3CCN(CC3)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C20 compound treatment 0.49 0.257 13.79 13.7905 1.0 1989042 ChemDiv2_008160 O=C(NCc1ccc2OCOc2c1)c3ccc4n(cnc4c3)C5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C21 compound treatment 0.237 0.00362 0.19 0.1948 1.0 1989043 ChemDiv2_008161 CC(Sc1nc2nc(C)cc(C)n2n1)C(=O)NCc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C22 compound treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1989044 ChemDiv2_008162 CC(C)CCN1CC(CC1=O)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C23 mock treatment 0.231 -0.00237 -0.13 -0.1276 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 C24 mock treatment 0.24 0.00662 0.36 0.356 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D01 compound treatment 0.242 0.00862 0.46 0.4635 1.0 1989045 ChemDiv2_008163 COc1ccc(OC)c(CNC(=O)Cn2nc(ccc2=O)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D02 compound treatment 0.365 0.132 7.07 7.0733 1.0 1989046 ChemDiv2_008164 Cc1nnc(Sc2cc(C(=O)N3CCC4(CC3)OCCO4)c5ccccc5n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D03 compound treatment 0.253 0.0196 1.05 1.0546 1.0 1989047 ChemDiv2_008165 O=C(Cn1nc(ccc1=O)c2ccccc2)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D04 compound treatment 0.419 0.186 9.98 9.9751 1.0 1739787 ChemDiv2_008166 COc1ccc(CCNC(=O)CC2Sc3ccccc3NC2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D05 compound treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1989048 ChemDiv2_008167 COc1ccc(CN2CC(CC2=O)C(=O)NCC3CCCO3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D06 compound treatment 0.473 0.24 12.88 12.8769 1.0 1989049 ChemDiv2_008168 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCC2CCC(CC2)C(=O)N3CCN(CC3)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D07 compound treatment 0.223 -0.0104 -0.56 -0.5575 -1.0 1989050 ChemDiv2_008169 O=C(NCCC1=CCCCC1)C2CN(C3CCCC3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D08 compound treatment 0.304 0.0706 3.8 3.7952 1.0 1989051 ChemDiv2_008170 CCN(C(=O)Cn1nc(ccc1=O)c2ccc(OC)cc2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D09 compound treatment 0.22 -0.0134 -0.72 -0.7187 -1.0 1989052 ChemDiv2_008171 Fc1ccccc1N2CCN(CCCNC(=O)C3CCC(=O)N3C4CCCC4)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D10 compound treatment 0.462 0.229 12.29 12.2858 1.0 1989053 ChemDiv2_008172 Fc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D11 compound treatment 0.459 0.226 12.12 12.1246 1.0 1989054 ChemDiv2_008173 Cc1ccc(CSCc2ccc(o2)C(=O)NCc3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D12 compound treatment 0.499 0.266 14.27 14.2741 1.0 1989055 ChemDiv2_008174 CSc1ccc(cc1)c2nc(CSCC(=O)N3C(C)CCCC3C)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D13 compound treatment 0.245 0.0116 0.62 0.6247 1.0 1989056 ChemDiv2_008175 CCCCN(C)C(=O)Cn1nc(ccc1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D14 compound treatment 0.4 0.167 8.95 8.9541 1.0 1989057 ChemDiv2_008176 Cc1nccc2[nH]c(=O)c(cc12)C(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D15 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989058 ChemDiv2_008177 Cc1ccc(CCN2CC(CC2=O)C(=O)NCCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D16 compound treatment 0.297 0.0636 3.42 3.4191 1.0 1989059 ChemDiv2_008178 COc1ccc(cc1OC)c2nc(CSCC(=O)NC3CCN(Cc4ccccc4)CC3)c(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D17 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989060 ChemDiv2_008179 Cc1ccc(CN2C(CCC2=O)C(=O)NCc3ccc4OCOc4c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D18 compound treatment 0.233 -3.75E-4 -0.02 -0.0202 -1.0 1989061 ChemDiv2_008180 CCOC(=O)N1CCC(CC1)NC(=O)c2cccnc2SC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D19 compound treatment 0.262 0.0286 1.54 1.5382 1.0 1989062 ChemDiv2_008181 CC1CCCCC1NC(=O)c2ccc(c(NC(=O)C)c2)S(=O)(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D20 compound treatment 0.406 0.173 9.28 9.2765 1.0 1415325 ChemDiv2_008182 C=CCN(c1ccccc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCC4CCCO4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D21 compound treatment 0.302 0.0686 3.69 3.6878 1.0 1989063 ChemDiv2_008183 CN(Cc1ccco1)C(=O)Cn2nc(ccc2=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D22 compound treatment 0.296 0.0626 3.37 3.3653 1.0 1989064 ChemDiv2_008184 COc1ccc(cc1)C2C=C(Nc3nc4ccccc4n23)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D23 mock treatment 0.236 0.00262 0.14 0.1411 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 D24 mock treatment 0.23 -0.00337 -0.18 -0.1814 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E01 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989065 ChemDiv2_008185 Cc1nn2c(cc(C)nc2c1c3ccc(Cl)cc3)N4CCC(CC4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E02 compound treatment 0.432 0.199 10.67 10.6737 1.0 1989066 ChemDiv2_008186 Cc1c(oc2ccc(cc12)S(=O)(=O)NC3CCCCC3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E03 compound treatment 0.435 0.202 10.83 10.8349 1.0 1212367 ChemDiv2_008187 CCOc1ccc(cc1)n2c(C)nc3cc(ccc23)C(=O)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E04 compound treatment 0.426 0.193 10.35 10.3513 1.0 1989067 ChemDiv2_008188 CCCN(CCC)C(=O)CSc1ncccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E05 compound treatment 0.239 0.00562 0.3 0.3023 1.0 1989068 ChemDiv2_008189 CCOC(=O)CN1C(=O)C(CC)Oc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E06 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989069 ChemDiv2_008190 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E07 compound treatment 0.484 0.251 13.47 13.4681 1.0 1989070 ChemDiv2_008191 O=C(NCc1ccccc1)c2ccc3nc4SCCc4cc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E08 compound treatment 0.237 0.00362 0.19 0.1948 1.0 1989071 ChemDiv2_008192 CN1CCN(CC1)C(=O)C2CNc3cc(C)ccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E09 compound treatment 0.237 0.00362 0.19 0.1948 1.0 1989072 ChemDiv2_008193 Cc1nccc2[nH]c(=O)c(cc12)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E10 compound treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1989073 ChemDiv2_008194 C=CCN1C(C(=O)NCc2cccnc2)c3ccccc3C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E11 compound treatment 0.214 -0.0194 -1.04 -1.0412 -1.0 1989074 ChemDiv2_008195 CCC(=O)N1C(CSC1c2ccc(OC)cc2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E12 compound treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1989075 ChemDiv2_008196 CCOc1ccc(CCNC(=O)c2cc(=O)[nH]c3ccc(cc23)S(=O)(=O)N4CCCC4)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E13 compound treatment 0.233 -3.75E-4 -0.02 -0.0202 -1.0 1989076 ChemDiv2_008197 CN(C)CCNC(=O)c1cc(Sc2ccc(F)cc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E14 compound treatment 0.429 0.196 10.51 10.5125 1.0 1989077 ChemDiv2_008198 Clc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)N3CCCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E15 compound treatment 0.399 0.166 8.9 8.9003 1.0 1989078 ChemDiv2_008199 CC(C)CCNC(=O)c1cnn2c(O)cc(CSc3ccc(Cl)cc3)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E16 compound treatment 0.412 0.179 9.6 9.5989 1.0 1989079 ChemDiv2_008200 CC1(C)CC(=O)c2cc(OCC(=O)NCC=C)ccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E17 compound treatment 0.271 0.0376 2.02 2.0219 1.0 1989080 ChemDiv2_008201 CCc1nc2ccc(cc2nc1CC)C(=O)NC(C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E18 compound treatment 0.349 0.116 6.21 6.2134 1.0 1989081 ChemDiv2_008202 CC(=O)Nc1ccc(cc1)S(=O)(=O)N(CCCN2CCOCC2)Cc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E19 compound treatment 0.398 0.165 8.85 8.8466 1.0 1989082 ChemDiv2_008203 Cc1nc2c(cnn2c(C)c1Cc3ccccc3)C(=O)NCCCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E20 compound treatment 0.336 0.103 5.51 5.5149 1.0 1989083 ChemDiv2_008204 O=C(NCCCN1CCCCC1)c2ccc3n(cnc3c2)C4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E21 compound treatment 0.25 0.0166 0.89 0.8934 1.0 1989084 ChemDiv2_008205 CC(Sc1nc2nc(C)cc(C)n2n1)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E22 compound treatment 0.238 0.00462 0.25 0.2485 1.0 1989085 ChemDiv2_008206 O=C(Cn1nc(ccc1=O)c2ccccc2)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E23 mock treatment 0.234 6.25E-4 0.03 0.0336 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 E24 mock treatment 0.238 0.00462 0.25 0.2485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F01 compound treatment 0.218 -0.0154 -0.83 -0.8262 -1.0 1989086 ChemDiv2_008207 CC(C)NC(=O)C1CCCN(C1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F02 compound treatment 0.52 0.287 15.4 15.4026 1.0 1989087 ChemDiv2_008208 O=C(CC1Sc2ccccc2NC1=O)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F03 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1989088 ChemDiv2_008209 CC(C)CCNC(=O)C1CN(CCC(C)C)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F04 compound treatment 0.378 0.145 7.77 7.7718 1.0 1989089 ChemDiv2_008210 Cc1ccccc1NS(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccccc4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F05 compound treatment 0.303 0.0696 3.74 3.7415 1.0 1989090 ChemDiv2_008211 Fc1ccc(cc1Cl)N2CC(CC2=O)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F06 compound treatment 0.283 0.0496 2.67 2.6667 1.0 1989091 ChemDiv2_008212 CCN1CCN(CC1)C(=O)C2CCC(CNS(=O)(=O)c3ccc(NC(=O)C)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F07 compound treatment 0.225 -0.00837 -0.45 -0.4501 -1.0 1989092 ChemDiv2_008213 O=C(NCCN1CCc2ccccc2C1)C3CN(C4CCCC4)C(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F08 compound treatment 0.286 0.0526 2.83 2.828 1.0 1989093 ChemDiv2_008214 COc1ccc(cc1)c2ccc(=O)n(CC(=O)Nc3ccc(C)cc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F09 compound treatment 0.225 -0.00837 -0.45 -0.4501 -1.0 1989094 ChemDiv2_008215 O=C(C1CCC(=O)N1C2CCCC2)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F10 compound treatment 0.281 0.0476 2.56 2.5593 1.0 1989095 ChemDiv2_008216 CC1CCN(CCCNC(=O)c2ccc(CS(=O)(=O)Cc3cccc(C)c3)o2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F11 compound treatment 0.486 0.253 13.58 13.5755 1.0 1989096 ChemDiv2_008217 Cc1ccc(CSCc2ccc(o2)C(=O)NCc3cccs3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F12 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989097 ChemDiv2_008218 CC1CN(CCN1c2cccc(C)c2)C(=O)CN3CCOc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F13 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989098 ChemDiv2_008219 Clc1ccc(cc1)c2ccc(=O)n(CC(=O)NCCCN3CCCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F14 compound treatment 0.446 0.213 11.43 11.426 1.0 1989099 ChemDiv2_008220 Cc1nccc2[nH]c(=O)c(cc12)C(=O)NCCN3CCN(CC3)c4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F15 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989100 ChemDiv2_008221 Fc1ccc(cc1)N2CCN(CC2)C(=O)C3CN(CCc4ccccc4)C(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F16 compound treatment 0.344 0.111 5.94 5.9448 1.0 1989101 ChemDiv2_008222 COc1ccccc1c2c(C)nn3c(cc(C)nc23)N4CCC(CC4)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F17 compound treatment 0.22 -0.0134 -0.72 -0.7187 -1.0 1989102 ChemDiv2_008223 CNC(=O)C1CCC(=O)N1Cc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F18 compound treatment 0.238 0.00462 0.25 0.2485 1.0 1989103 ChemDiv2_008224 COc1ccc(C(=O)Nc2cc(Cl)cc(Cl)c2)c(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F19 compound treatment 0.434 0.201 10.78 10.7812 1.0 1989104 ChemDiv2_008225 CC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(Cl)cc2)C(=O)NCCc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F20 compound treatment 0.286 0.0526 2.83 2.828 1.0 1737255 ChemDiv2_008226 O=C(NCc1ccccc1)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)N4CCC5(CC4)OCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F21 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989105 ChemDiv2_008227 Fc1ccc(cc1)N2CCN(CC2)C(=O)C3CCC(=O)N3Cc4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F22 compound treatment 0.311 0.0776 4.17 4.1714 1.0 1989106 ChemDiv2_008228 Clc1cccc(c1)C2C=C(Nc3nc4ccccc4n23)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F23 mock treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 F24 mock treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G01 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1288469 ChemDiv2_008229 Brc1ccccc1n2c(SCC#N)nc3[nH]ncc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G02 compound treatment 0.267 0.0336 1.81 1.8069 1.0 1989107 ChemDiv2_008230 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NCc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G03 compound treatment 0.427 0.194 10.41 10.405 1.0 1297603 ChemDiv2_008231 COc1ccc(OC)c(NC(=O)c2cc(ccc2F)S(=O)(=O)NCC3COc4ccccc4O3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G04 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989108 ChemDiv2_008232 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncccc2C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G05 compound treatment 0.359 0.126 6.75 6.7508 1.0 1989109 ChemDiv2_008233 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G06 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989110 ChemDiv2_008234 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NC2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G07 compound treatment 0.324 0.0906 4.87 4.87 1.0 1989111 ChemDiv2_008235 Cc1ccc(CCNC(=O)c2cnc3ccc(cc3c2Cl)S(=O)(=O)N4CCOCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G08 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989112 ChemDiv2_008236 O=C(NCC1CCCO1)C2CCN(CC2)S(=O)(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G09 compound treatment 0.437 0.204 10.94 10.9424 1.0 1989113 ChemDiv2_008237 Cc1ccc(cc1)S(=O)(=O)N2CCC(=CC2)C(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G10 compound treatment 0.264 0.0306 1.65 1.6457 1.0 1989114 ChemDiv2_008238 CN(CCNC(=O)c1ccc(Sc2ccc(F)cc2)c(NC(=O)C)c1)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G11 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989115 ChemDiv2_008239 CCC(=O)N1C(CSC1c2ccc(OC)cc2)C(=O)NCc3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G12 compound treatment 0.268 0.0346 1.86 1.8607 1.0 1989116 ChemDiv2_008240 CC(=O)Nc1cc(ccc1Sc2ccc(C)cc2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G13 compound treatment 0.386 0.153 8.2 8.2017 1.0 1989117 ChemDiv2_008241 CC1CCC(CC1)NC(=O)c2ccc3SCC(=O)Nc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G14 compound treatment 0.491 0.258 13.84 13.8442 1.0 1989118 ChemDiv2_008242 CN(Cc1ccccc1)C(=O)c2ccc(CS(=O)(=O)Cc3ccc(Cl)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G15 compound treatment 0.253 0.0196 1.05 1.0546 1.0 1483330 ChemDiv2_008243 O=C(NC1CC1)c2cc(nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G16 compound treatment 0.345 0.112 6.0 5.9985 1.0 1989119 ChemDiv2_008244 CCOC(=O)c1cccnc1SCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G17 compound treatment 0.233 -3.75E-4 -0.02 -0.0202 -1.0 1989120 ChemDiv2_008245 CN(C)CCNC(=O)c1ccc2nc(C)c(C)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G18 compound treatment 0.261 0.0276 1.48 1.4845 1.0 1989121 ChemDiv2_008246 CCC1Oc2ccccc2N(CC(=O)N(C)Cc3ccccc3)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G19 compound treatment 0.25 0.0166 0.89 0.8934 1.0 1989122 ChemDiv2_008247 Cc1c(Cl)cccc1NC(=O)CN2C(=O)C3(OCCCO3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G20 compound treatment 0.293 0.0596 3.2 3.2041 1.0 1989123 ChemDiv2_008248 CCC(Oc1ccc2OC(C)(C)CC(=O)c2c1)C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G21 compound treatment 0.268 0.0346 1.86 1.8607 1.0 1989124 ChemDiv2_008249 Cc1cc(C)n2nc(SCCC(=O)NCc3ccccc3)nc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G22 compound treatment 0.256 0.0226 1.22 1.2158 1.0 1989125 ChemDiv2_008250 COc1ccc(CCNC(=O)Cn2nc(ccc2=O)c3ccccc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G23 mock treatment 0.241 0.00762 0.41 0.4098 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 G24 mock treatment 0.236 0.00262 0.14 0.1411 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H01 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989126 ChemDiv2_008251 O=C(NC1CC1)C2CCN(CC2)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H02 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989127 ChemDiv2_008252 CN1CCN(CC1)C(=O)C2CCC(=O)N2Cc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H03 compound treatment 0.505 0.272 14.6 14.5966 1.0 1989128 ChemDiv2_008253 Clc1ccccc1CSCc2ccc(o2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H04 compound treatment 0.242 0.00862 0.46 0.4635 1.0 1989129 ChemDiv2_008254 O=C(NC1CC1)c2cc(nc3ccc(cc23)S(=O)(=O)N4CCCCCC4)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H05 compound treatment 0.266 0.0326 1.75 1.7532 1.0 1989130 ChemDiv2_008255 CCC(C)N1CC(CC1=O)C(=O)NCCc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H06 compound treatment 0.258 0.0246 1.32 1.3233 1.0 1989131 ChemDiv2_008256 COc1ccc(cc1)N2CCN(CCCNC(=O)C3CCN(CC3)S(=O)(=O)N4CCOCC4)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H07 compound treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1989132 ChemDiv2_008257 CN(CCNC(=O)C1CN(C2CCCC2)C(=O)C1)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H08 compound treatment 0.432 0.199 10.67 10.6737 1.0 1989133 ChemDiv2_008258 Clc1cccc(CSCc2ccc(o2)C(=O)NCc3ccccn3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H09 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989134 ChemDiv2_008259 O=C(NCc1cccs1)C2CCC(=O)N2C3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H10 compound treatment 0.326 0.0926 4.98 4.9775 1.0 1989135 ChemDiv2_008260 O=C(NC1CC1)c2ccc(CS(=O)(=O)c3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H11 compound treatment 0.53 0.297 15.94 15.94 1.0 1989136 ChemDiv2_008261 Cc1ccc(CSCc2ccc(o2)C(=O)NC3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H12 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989137 ChemDiv2_008262 CC(CCc1ccccc1)NC(=O)CN2CCOc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H13 compound treatment 0.528 0.295 15.83 15.8325 1.0 1989138 ChemDiv2_008263 CC(C)NC(=O)c1ccc(CSCc2cccc(C)c2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H14 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989139 ChemDiv2_008264 Cc1nccc2[nH]c(=O)c(cc12)C(=O)NC3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H15 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989140 ChemDiv2_008265 O=C(NCCc1ccccc1)C2CN(CCc3ccccc3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H16 compound treatment 0.289 0.0556 2.99 2.9892 1.0 1989141 ChemDiv2_008266 CC(N1CCC(CNC(=O)c2ccc(CS(=O)(=O)c3ccccc3C)o2)C1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H17 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989142 ChemDiv2_008267 CCCCN1CC(CC1=O)C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H18 compound treatment 0.403 0.17 9.12 9.1153 1.0 1989143 ChemDiv2_008268 CCOC(=O)N1CCN(CC1)C(=O)CCC(=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H19 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989144 ChemDiv2_008269 CCCS(=O)(=O)N1CCCC(C1)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H20 compound treatment 0.242 0.00862 0.46 0.4635 1.0 1989145 ChemDiv2_008270 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccc(C)cc4)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H21 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989146 ChemDiv2_008271 CNC(=O)C1CCC(=O)N1Cc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H22 compound treatment 0.23 -0.00337 -0.18 -0.1814 -1.0 1989147 ChemDiv2_008272 Fc1ccc(cc1)C2C3=C(CCCC3=O)Nc4nc5ccccc5n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H23 mock treatment 0.237 0.00362 0.19 0.1948 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 H24 mock treatment 0.231 -0.00237 -0.13 -0.1276 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I01 compound treatment 0.235 0.00162 0.09 0.0873 1.0 1736990 ChemDiv2_008273 C=CCN(C(=O)CSc1nc2[nH]ncc2c(=O)n1c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I02 compound treatment 0.276 0.0426 2.29 2.2906 1.0 1989148 ChemDiv2_008274 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I03 compound treatment 0.278 0.0446 2.4 2.3981 1.0 1214949 ChemDiv2_008275 Cc1nc2cc(ccc2n1c3cccc(C)c3)C(=O)N4CCC5(CC4)OCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I04 compound treatment 0.481 0.248 13.31 13.3068 1.0 1989149 ChemDiv2_008276 CC1CC(C)CN(C1)C(=O)CSc2ncccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I05 compound treatment 0.23 -0.00337 -0.18 -0.1814 -1.0 1989150 ChemDiv2_008277 OC(=O)CN1C(=O)COc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I06 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989151 ChemDiv2_008278 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I07 compound treatment 0.233 -3.75E-4 -0.02 -0.0202 -1.0 1989152 ChemDiv2_008279 Cc1nn2c(cc(C)nc2c1c3ccc(Cl)cc3)N4CCC5(CC4)OCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I08 compound treatment 0.452 0.219 11.75 11.7485 1.0 1989153 ChemDiv2_008280 COc1ccc(NC(=O)c2oc3ccc(cc3c2C)S(=O)(=O)N(C)C4CCCCC4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I09 compound treatment 0.339 0.106 5.68 5.6761 1.0 1989154 ChemDiv2_008281 CN1CCSc2ccc(cc12)C(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I10 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989155 ChemDiv2_008282 CC(=O)Nc1cc(ccc1Sc2ccc(F)cc2)C(=O)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I11 compound treatment 0.27 0.0366 1.97 1.9682 1.0 1989156 ChemDiv2_008283 OC(=O)c1c2CCCCc2nc3ccc(cc13)S(=O)(=O)N4CCC(CC4)C(=O)NCc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I12 compound treatment 0.513 0.28 15.03 15.0265 1.0 1989157 ChemDiv2_008284 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)N4CCC5(CC4)OCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I13 compound treatment 0.25 0.0166 0.89 0.8934 1.0 1989158 ChemDiv2_008285 Cc1ccc(CNC(=O)Cc2nc3nc(C)cc(C)n3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I14 compound treatment 0.475 0.242 12.98 12.9844 1.0 1989159 ChemDiv2_008286 CC1CCCCC1NC(=O)c2ccc(CS(=O)(=O)Cc3ccc(Cl)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I15 compound treatment 0.252 0.0186 1.0 1.0009 1.0 1436117 ChemDiv2_008287 O=C(NCC1CCCO1)c2cc(nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I16 compound treatment 0.23 -0.00337 -0.18 -0.1814 -1.0 1989160 ChemDiv2_008288 COC(=O)c1ccccc1S(=O)(=O)N(CCCN2CCOCC2)Cc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I17 compound treatment 0.248 0.0146 0.79 0.7859 1.0 1989161 ChemDiv2_008289 Cc1nc2ccc(cc2nc1C)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I18 compound treatment 0.25 0.0166 0.89 0.8934 1.0 1989162 ChemDiv2_008290 CCC(Oc1ccc2OC(C)(C)CC(=O)c2c1)C(=O)NCCN3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I19 compound treatment 0.238 0.00462 0.25 0.2485 1.0 1989163 ChemDiv2_008291 CCC(N1C(=O)C2(OCCCO2)c3ccccc13)C(=O)Nc4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I20 compound treatment 0.256 0.0226 1.22 1.2158 1.0 1989164 ChemDiv2_008292 O=C(NCCc1ccccc1)C2CN(C3CCCCCC3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I21 compound treatment 0.245 0.0116 0.62 0.6247 1.0 1989165 ChemDiv2_008293 O=C(NCCN1CCOCC1)c2cc(nc3ccccc23)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I22 compound treatment 0.252 0.0186 1.0 1.0009 1.0 1989166 ChemDiv2_008294 O=C(Cn1nc(ccc1=O)c2ccccc2)NCCCN3CCC(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I23 mock treatment 0.239 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 I24 mock treatment 0.236 0.00262 0.14 0.1411 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J01 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989167 ChemDiv2_008295 CC1CCCN(CCCNC(=O)Cn2nc(ccc2=O)c3ccccc3)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J02 compound treatment 0.238 0.00462 0.25 0.2485 1.0 1989168 ChemDiv2_008296 Fc1ccc(CN2C(CCC2=O)C(=O)NCCN3CCOCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J03 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989169 ChemDiv2_008297 CS(=O)(=O)N1CCCC(C1)C(=O)NCCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J04 compound treatment 0.614 0.381 20.45 20.454 1.0 1989170 ChemDiv2_008298 COc1ccccc1N2CCN(CC2)C(=O)c3ccc4Sc5ccccc5C(=O)N(CC=C)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J05 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989171 ChemDiv2_008299 CCC(C)N1CC(CC1=O)C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J06 compound treatment 0.408 0.175 9.38 9.384 1.0 1989172 ChemDiv2_008300 COc1ccc(NC(=O)CN2C(=O)c3ccccc3Sc4ccc(cc24)C(=O)N5CCCC5)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J07 compound treatment 0.244 0.0106 0.57 0.571 1.0 1989173 ChemDiv2_008301 COc1ccc(CN2CC(CC2=O)C(=O)NC3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J08 compound treatment 0.434 0.201 10.78 10.7812 1.0 1989174 ChemDiv2_008302 Clc1cccc(CSCc2ccc(o2)C(=O)NCCCN3CCCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J09 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989175 ChemDiv2_008303 CCOc1ccc(CNC(=O)C2CCC(=O)N2C3CCCC3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J10 compound treatment 0.323 0.0896 4.82 4.8163 1.0 1989176 ChemDiv2_008304 Cc1oc(nc1CSCC(=O)N2CCC(CC2)C(=O)N)c3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J11 compound treatment 0.498 0.265 14.22 14.2204 1.0 1989177 ChemDiv2_008305 Cc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NC3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J12 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989178 ChemDiv2_008306 O=C(CN1CCOc2ccccc12)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J13 compound treatment 0.305 0.0716 3.85 3.849 1.0 1989179 ChemDiv2_008307 CC(C)CCNC(=O)c1ccc(CS(=O)(=O)Cc2ccccc2C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J14 compound treatment 0.276 0.0426 2.29 2.2906 1.0 1989180 ChemDiv2_008308 NC(=O)C1CCN(CC1)C(=O)c2ccc(CS(=O)(=O)c3c(Cl)cccc3Cl)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J15 compound treatment 0.239 0.00562 0.3 0.3023 1.0 1989181 ChemDiv2_008309 O=C(NCC1CCCO1)C2CN(CCc3ccccc3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J16 compound treatment 0.474 0.241 12.93 12.9307 1.0 1989182 ChemDiv2_008310 COc1ccc(OC)c(CCNC(=O)c2ccc(CS(=O)(=O)c3c(Cl)cccc3Cl)o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J17 compound treatment 0.301 0.0676 3.63 3.634 1.0 1989183 ChemDiv2_008311 CNC(=O)C1CN(C(=O)C1)c2ccc(F)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J18 compound treatment 0.285 0.0516 2.77 2.7742 1.0 1678833 ChemDiv2_008312 COC(=O)Cc1nc(N2CCC(C)CC2)c3c4CCCCc4sc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J19 compound treatment 0.246 0.0126 0.68 0.6784 1.0 1989184 ChemDiv2_008313 CC(C)CCN1CC(CC1=O)C(=O)N2CCN(CC2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J20 compound treatment 0.276 0.0426 2.29 2.2906 1.0 1989185 ChemDiv2_008314 CCN(CC)S(=O)(=O)c1ccc2[nH]cc(C(=O)NCc3ccc(F)cc3)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J21 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989186 ChemDiv2_008315 Clc1ccccc1CN2C(CCC2=O)C(=O)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J22 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989187 ChemDiv2_008316 COc1ccc(cc1OC)C2C(=C(C)Nc3nc4ccccc4n23)C(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J23 mock treatment 0.23 -0.00337 -0.18 -0.1814 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 J24 mock treatment 0.225 -0.00837 -0.45 -0.4501 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K01 compound treatment 0.246 0.0126 0.68 0.6784 1.0 1399753 ChemDiv2_008317 CCOc1ccc(NC(=O)CSc2nc3[nH]ncc3c(=O)n2c4ccccc4OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K02 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989188 ChemDiv2_008318 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K03 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1989189 ChemDiv2_008319 OC(=O)Cc1c(nc2ccccc2c1C(=O)O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K04 compound treatment 0.482 0.249 13.36 13.3606 1.0 1989190 ChemDiv2_008320 CCN(C(=O)CSc1ncccc1C(=O)O)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K05 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989191 ChemDiv2_008321 CCC1Oc2ccccc2N(Cc3ccccc3Cl)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K06 compound treatment 0.233 -3.75E-4 -0.02 -0.0202 -1.0 1989192 ChemDiv2_008322 C=CCSc1ncccc1C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K07 compound treatment 0.235 0.00162 0.09 0.0873 1.0 1989193 ChemDiv2_008323 Cc1oc(nc1CN2CCCCC2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K08 compound treatment 0.289 0.0556 2.99 2.9892 1.0 1989194 ChemDiv2_008324 Cc1ccc2[nH]c(nc2c1)N3CCC(CC3)C(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K09 compound treatment 0.314 0.0806 4.33 4.3326 1.0 1989195 ChemDiv2_008325 CN1CCSc2ccc(cc12)C(=O)Nc3cc(F)ccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K10 compound treatment 0.466 0.233 12.5 12.5008 1.0 1989196 ChemDiv2_008326 CCOC(=O)c1cccnc1SCC(=O)Nc2cc(OC)ccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K11 compound treatment 0.5 0.267 14.33 14.3279 1.0 1989197 ChemDiv2_008327 CCCNC(=O)C1CCN(CC1)c2nc3ccc(CC)cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K12 compound treatment 0.503 0.27 14.49 14.4891 1.0 1989198 ChemDiv2_008328 CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K13 compound treatment 0.285 0.0516 2.77 2.7742 1.0 1989199 ChemDiv2_008329 COc1ccc(cc1)c2nc3ccc(cc3nc2c4ccc(OC)cc4)C(=O)NC5CC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K14 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989200 ChemDiv2_008330 O=C(CN1C(=O)CSc2ccccc12)NCCC3=CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K15 compound treatment 0.248 0.0146 0.79 0.7859 1.0 1989201 ChemDiv2_008331 Cc1cc(C)n2nc(SCC(=O)NC3CCCc4ccccc34)nc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K16 compound treatment 0.272 0.0386 2.08 2.0756 1.0 1989202 ChemDiv2_008332 Clc1ccc(cc1)S(=O)(=O)N(CCCN2CCOCC2)Cc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K17 compound treatment 0.313 0.0796 4.28 4.2789 1.0 1989203 ChemDiv2_008333 Cc1nc2ccc(cc2nc1C)C(=O)NCC3COc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K18 compound treatment 0.486 0.253 13.58 13.5755 1.0 1989204 ChemDiv2_008334 CC(C)CCNC(=O)c1ccc2n(cnc2c1)C3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K19 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989205 ChemDiv2_008335 COc1ccc(OC)c(NC(=O)CN2C(=O)C3(OCCCO3)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K20 compound treatment 0.235 0.00162 0.09 0.0873 1.0 1989206 ChemDiv2_008336 O=C(NCc1ccccc1)C2CN(C3CCCCCC3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K21 compound treatment 0.261 0.0276 1.48 1.4845 1.0 1989207 ChemDiv2_008337 O=C(NCC1COc2ccccc2O1)c3cc(nc4ccccc34)c5ccncc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K22 compound treatment 0.299 0.0656 3.53 3.5266 1.0 1989208 ChemDiv2_008338 O=C(Cn1nc(ccc1=O)c2ccccc2)NCCCN3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K23 mock treatment 0.231 -0.00237 -0.13 -0.1276 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 K24 mock treatment 0.228 -0.00537 -0.29 -0.2888 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L01 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989209 ChemDiv2_008339 CC1CCCCN1CCNC(=O)Cn2nc(ccc2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L02 compound treatment 0.506 0.273 14.65 14.6503 1.0 1989210 ChemDiv2_008340 O=C(NC1CCCC1)c2ccc3n(cnc3c2)C4CCCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L03 compound treatment 0.232 -0.00137 -0.07 -0.0739 -1.0 1989211 ChemDiv2_008341 CS(=O)(=O)N1CCCC(C1)C(=O)N2CCC3(CC2)OCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L04 compound treatment 0.534 0.301 16.15 16.155 1.0 1989212 ChemDiv2_008342 O=C(N1CCN(CC1)c2ccccc2)c3coc4nc5ccccc5nc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L05 compound treatment 0.269 0.0356 1.91 1.9144 1.0 1989213 ChemDiv2_008343 O=C(NCc1ccc2OCOc2c1)C3CN(C4CCCCCCC4)C(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L06 compound treatment 0.323 0.0896 4.82 4.8163 1.0 1989214 ChemDiv2_008344 CC(NC(=O)c1ccc(CS(=O)(=O)Cc2ccccc2F)o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L07 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989215 ChemDiv2_008345 C=CCNC(=O)C1CCN(CC1)S(=O)(=O)N2CCC3(CC2)OCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L08 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989216 ChemDiv2_008346 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(Cl)cc2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L09 compound treatment 0.282 0.0486 2.61 2.613 1.0 1989217 ChemDiv2_008347 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L10 compound treatment 0.248 0.0146 0.79 0.7859 1.0 1989218 ChemDiv2_008348 CN(CCC#N)c1cc(C)nc2c(c(C)nn12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L11 compound treatment 0.426 0.193 10.35 10.3513 1.0 1989219 ChemDiv2_008349 Cc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCC3CCCO3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L12 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989220 ChemDiv2_008350 O=C(CN1CCOc2ccccc12)NC3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L13 compound treatment 0.333 0.0996 5.35 5.3536 1.0 1989221 ChemDiv2_008351 CC(NC(=O)c1ccc(CS(=O)(=O)Cc2ccccc2C)o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L14 compound treatment 0.244 0.0106 0.57 0.571 1.0 1989222 ChemDiv2_008352 CN(C)CCNC(=O)c1ccc(CS(=O)(=O)c2c(Cl)cccc2Cl)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L15 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989223 ChemDiv2_008353 O=C(NCCCN1CCCCC1)C2CN(C3CCCCC3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L16 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1989224 ChemDiv2_008354 Cc1oc(nc1CS(=O)CC(=O)Nc2ccc(F)cc2C)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L17 compound treatment 0.248 0.0146 0.79 0.7859 1.0 1989225 ChemDiv2_008355 CC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(Cl)cc2)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L18 compound treatment 0.389 0.156 8.36 8.363 1.0 1989226 ChemDiv2_008356 CCOC(=O)c1cc(C)n(CCc2ccccc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L19 compound treatment 0.221 -0.0124 -0.67 -0.665 -1.0 1989227 ChemDiv2_008357 CC(C)NC(=O)C1CCC(=O)N1Cc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L20 compound treatment 0.366 0.133 7.13 7.127 1.0 1989228 ChemDiv2_008358 O=C(NCCc1ccccc1)c2c[nH]c3ccc(cc3c2=O)S(=O)(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L21 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989229 ChemDiv2_008359 Clc1ccccc1CN2C(CCC2=O)C(=O)NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L22 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989230 ChemDiv2_008360 CCC1=C(C(c2ccccc2OC)n3ncnc3N1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L23 mock treatment 0.239 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 L24 mock treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M01 compound treatment 0.233 -3.75E-4 -0.02 -0.0202 -1.0 1440390 ChemDiv2_008361 COC(=O)c1cn(nc1N)C(=O)c2cc(OC)cc(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M02 compound treatment 0.242 0.00862 0.46 0.4635 1.0 1989231 ChemDiv2_008362 CCN(CC)S(=O)(=O)N1CCC(CC1)C(=O)NCc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M03 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989232 ChemDiv2_008363 Cc1ccc(cc1)c2nc3ccccc3c(C(=O)O)c2CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M04 compound treatment 0.237 0.00362 0.19 0.1948 1.0 1989233 ChemDiv2_008364 CCC1CCCCN1C(=O)CSc2ncccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M05 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989234 ChemDiv2_008365 Cn1cc(CN2CCN(CC2)c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M06 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989235 ChemDiv2_008366 CC(C)NC(=O)C1CCN(CC1)S(=O)(=O)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M07 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989236 ChemDiv2_008367 Cc1cccc(Cc2c(C)nc(O)c(C#N)c2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M08 compound treatment 0.251 0.0176 0.95 0.9471 1.0 1989237 ChemDiv2_008368 Cc1ccc(CNC(=O)c2sc3ccc(cc3c2N)S(=O)(=O)N4CCCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M09 compound treatment 0.295 0.0616 3.31 3.3116 1.0 1989238 ChemDiv2_008369 CCOc1ccc(NC(=O)c2ccc3SCCN(C)c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M10 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1989239 ChemDiv2_008370 CN(C(=O)CSc1ncccc1C(=O)Oc2ccccc2Cl)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M11 compound treatment 0.251 0.0176 0.95 0.9471 1.0 1200058 ChemDiv2_008371 CCCN(CCC)C(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N(CC)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M12 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989240 ChemDiv2_008372 CCOC(=O)c1cccnc1SCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M13 compound treatment 0.249 0.0156 0.84 0.8397 1.0 1989241 ChemDiv2_008373 Cc1c2CCCCc2nc3c(cnn13)C(=O)NCc4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M14 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989242 ChemDiv2_008374 CCOc1ccc(CCNC(=O)CN2C(=O)CSc3ccccc23)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M15 compound treatment 0.246 0.0126 0.68 0.6784 1.0 1989243 ChemDiv2_008375 CC1CCCC(C)N1CCCNC(=O)c2c(C)cc(=O)oc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M16 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1989244 ChemDiv2_008376 CC(N1C(=O)CCC1(C)C(=O)NC2CCCC(C)C2C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M17 compound treatment 0.459 0.226 12.12 12.1246 1.0 1989245 ChemDiv2_008377 C=CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M18 compound treatment 0.474 0.241 12.93 12.9307 1.0 1989246 ChemDiv2_008378 COc1ccc(OC)c(CNC(=O)c2ccc3n(cnc3c2)C4CCCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M19 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989247 ChemDiv2_008379 CCC(N1C(=O)C2(OCCCO2)c3ccccc13)C(=O)Nc4ccccc4CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M20 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989248 ChemDiv2_008380 CCC(C)N1C(CCC1=O)C(=O)N2CCN(CC2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M21 compound treatment 0.247 0.0136 0.73 0.7322 1.0 1989249 ChemDiv2_008381 O=C(NCCCN1CCCCC1)c2cc(nc3ccccc23)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M22 compound treatment 0.252 0.0186 1.0 1.0009 1.0 1989250 ChemDiv2_008382 CC1CCCCC1NC(=O)Cn2nc(ccc2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M23 mock treatment 0.234 6.25E-4 0.03 0.0336 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 M24 mock treatment 0.239 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N01 compound treatment 0.249 0.0156 0.84 0.8397 1.0 1989251 ChemDiv2_008383 Clc1cccc(c1)N2CCN(CCNC(=O)Cn3nc(ccc3=O)c4ccccc4)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N02 compound treatment 0.5 0.267 14.33 14.3279 1.0 1989252 ChemDiv2_008384 CCC1=Nc2cc(ccc2Sc3ccc(C)cc13)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N03 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989253 ChemDiv2_008385 CC(C)CN(CC(C)C)S(=O)(=O)N1CCC(CC1)C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N04 compound treatment 0.274 0.0406 2.18 2.1831 1.0 1989254 ChemDiv2_008386 O=C(NCCCN1CCCC1=O)C2CCC(CNS(=O)(=O)c3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N05 compound treatment 0.23 -0.00337 -0.18 -0.1814 -1.0 1989255 ChemDiv2_008387 O=C(NC1CC1)C2CN(C3CCCCC3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N06 compound treatment 0.396 0.163 8.74 8.7391 1.0 1989256 ChemDiv2_008388 CC1CN(CCN1C(=O)c2cccc(c2)N3CCCC3=O)c4cccc(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N07 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989257 ChemDiv2_008389 CN1CCN(CCCNC(=O)C2CCN(CC2)S(=O)(=O)N3CCC4(CC3)OCCO4)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N08 compound treatment 0.322 0.0886 4.76 4.7625 1.0 1989258 ChemDiv2_008390 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(Cl)cc2)C(=O)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N09 compound treatment 0.284 0.0506 2.72 2.7205 1.0 1989259 ChemDiv2_008391 CCCC(=O)Nc1cc(ccc1S(=O)(=O)c2ccc(C)cc2)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N10 compound treatment 0.367 0.134 7.18 7.1807 1.0 1989260 ChemDiv2_008392 Fc1cccc(CSCc2ccc(o2)C(=O)NCc3cccnc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N11 compound treatment 0.33 0.0966 5.19 5.1924 1.0 1989261 ChemDiv2_008393 Cc1ccc(CS(=O)(=O)Cc2ccc(o2)C(=O)NCc3ccccn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N12 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989262 ChemDiv2_008394 O=C(CN1CCOc2ccccc12)N3CCC(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N13 compound treatment 0.262 0.0286 1.54 1.5382 1.0 1989263 ChemDiv2_008395 Cc1ccccc1CS(=O)(=O)Cc2ccc(o2)C(=O)NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N14 compound treatment 0.339 0.106 5.68 5.6761 1.0 1989264 ChemDiv2_008396 Clc1cccc(Cl)c1S(=O)(=O)Cc2ccc(o2)C(=O)NC3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N15 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989265 ChemDiv2_008397 CCC(C)NC(=O)C1CN(C2CCCCC2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N16 compound treatment 0.236 0.00262 0.14 0.1411 1.0 1989266 ChemDiv2_008398 Brc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NCCCN3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N17 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989267 ChemDiv2_008399 CCS(=O)(=O)N1CCCC(C1)C(=O)NCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N18 compound treatment 0.246 0.0126 0.68 0.6784 1.0 1989268 ChemDiv2_008400 CCC(CC)C(=O)c1c(O)c2ccccc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N19 compound treatment 0.239 0.00562 0.3 0.3023 1.0 1989269 ChemDiv2_008401 Clc1ccccc1CN2C(CCC2=O)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N20 compound treatment 0.407 0.174 9.33 9.3302 1.0 1136172 ChemDiv2_008402 CN(CCC#N)S(=O)(=O)c1ccc2[nH]cc(C(=O)N(CC3CCCO3)Cc4ccco4)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N21 compound treatment 0.439 0.206 11.05 11.0499 1.0 1989270 ChemDiv2_008403 Cc1nnc(Sc2cc(C(=O)NCCCN3CCOCC3)c4ccccc4n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N22 compound treatment 0.237 0.00362 0.19 0.1948 1.0 1414727 ChemDiv2_008404 Cc1c(sc2ncn(C)c(=O)c12)C(=O)Oc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N23 mock treatment 0.243 0.00962 0.52 0.5172 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 N24 mock treatment 0.221 -0.0124 -0.67 -0.665 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O01 compound treatment 0.238 0.00462 0.25 0.2485 1.0 1989271 ChemDiv2_008405 CC1CCN(CC1)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCN(CC4)c5ccc(F)cc5)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O02 compound treatment 0.24 0.00662 0.36 0.356 1.0 1989272 ChemDiv2_008406 CCN(CC)S(=O)(=O)c1ccc2[nH]cc(C(=O)NCCCN3CCCCC3)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O03 compound treatment 0.245 0.0116 0.62 0.6247 1.0 1989273 ChemDiv2_008407 CCOC(=O)c1ccc2SCC(=O)N(CC=C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O04 compound treatment 0.286 0.0526 2.83 2.828 1.0 1989274 ChemDiv2_008408 CCC(Sc1ncccc1C(=O)O)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O05 compound treatment 0.225 -0.00837 -0.45 -0.4501 -1.0 1989275 ChemDiv2_008409 Cn1cc(CN2CCc3ccccc3C2)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O06 compound treatment 0.358 0.125 6.7 6.6971 1.0 1989276 ChemDiv2_008410 Cc1c(oc2ccc(cc12)S(=O)(=O)N3CCOCC3)C(=O)N4CCCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O07 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989277 ChemDiv2_008411 Cc1cc(C)c(C#N)c(OCc2ccccc2Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O08 compound treatment 0.241 0.00762 0.41 0.4098 1.0 1989278 ChemDiv2_008412 Cn1cc(CCC(=O)NC2CC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O09 compound treatment 0.237 0.00362 0.19 0.1948 1.0 1989279 ChemDiv2_008413 Cc1cc(C)c2c(=O)n(CC(=O)NC3CCCC3)sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O10 compound treatment 0.256 0.0226 1.22 1.2158 1.0 1989280 ChemDiv2_008414 CCC1CCCCN1C(=O)CSc2ncccc2C(=O)Oc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O11 compound treatment 0.272 0.0386 2.08 2.0756 1.0 1989281 ChemDiv2_008415 O=C(NCC1CCCO1)c2ccc3nc(c4ccccc4)c(nc3c2)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O12 compound treatment 0.255 0.0216 1.16 1.1621 1.0 1989282 ChemDiv2_008416 CC1CCN(CC1)S(=O)(=O)N2CCC(CC2)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O13 compound treatment 0.278 0.0446 2.4 2.3981 1.0 1989283 ChemDiv2_008417 CC1CCCCC1NC(=O)c2cnn3c(C)c4CCCCc4nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O14 compound treatment 0.248 0.0146 0.79 0.7859 1.0 1989284 ChemDiv2_008418 Cc1ccc(CCNC(=O)CCCc2cn(C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O15 compound treatment 0.257 0.0236 1.27 1.2696 1.0 1989285 ChemDiv2_008419 Cc1cc(=O)oc(C)c1C(=O)NCCCN2CCN(CC2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O16 compound treatment 0.255 0.0216 1.16 1.1621 1.0 1989286 ChemDiv2_008420 CC(=O)Nc1cc(ccc1Sc2ccc(C)cc2)C(=O)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O17 compound treatment 0.544 0.311 16.69 16.6923 1.0 1989287 ChemDiv2_008421 C=CCN1C(=O)c2ccccc2Sc3ccc(cc13)C(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O18 compound treatment 0.461 0.228 12.23 12.2321 1.0 1989288 ChemDiv2_008422 O=C(NCc1cccs1)c2ccc3n(cnc3c2)C4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O19 compound treatment 0.25 0.0166 0.89 0.8934 1.0 1989289 ChemDiv2_008423 Cc1ccc(CN2C(=O)C3(OCCCO3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O20 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989290 ChemDiv2_008424 C=CCNC(=O)C1CN(C2CCCCCC2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O21 compound treatment 0.234 6.25E-4 0.03 0.0336 1.0 1989291 ChemDiv2_008425 O=C(NCc1ccccc1)c2cc(nc3ccccc23)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O22 compound treatment 0.256 0.0226 1.22 1.2158 1.0 1989292 ChemDiv2_008426 C=CCNC(=O)Cn1nc(ccc1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O23 mock treatment 0.255 0.0216 1.16 1.1621 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 O24 mock treatment 0.246 0.0126 0.68 0.6784 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P01 compound treatment 0.229 -0.00437 -0.24 -0.2351 -1.0 1989293 ChemDiv2_008427 O=C(Cn1nc(ccc1=O)c2ccccc2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P02 compound treatment 0.216 -0.0174 -0.93 -0.9337 -1.0 1989294 ChemDiv2_008428 CN(Cc1ccco1)C(=O)C2CCC(=O)N2Cc3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P03 compound treatment 0.222 -0.0114 -0.61 -0.6113 -1.0 1989295 ChemDiv2_008429 O=C(NCCc1ccccc1)C2CCC(=O)N2C3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P04 compound treatment 0.215 -0.0184 -0.99 -0.9874 -1.0 1989296 ChemDiv2_008430 Cc1ccc(CN2C(=O)CN=C(c3ccccc3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P05 compound treatment 0.207 -0.0264 -1.42 -1.4173 -1.0 1989297 ChemDiv2_008431 O=C(NC1CCCCC1)C2CCC(=O)N2C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P06 compound treatment 0.243 0.00962 0.52 0.5172 1.0 1989298 ChemDiv2_008432 O=C(NCCCN1CCCC1)c2cccc(c2)N3CCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P07 compound treatment 0.217 -0.0164 -0.88 -0.88 -1.0 1989299 ChemDiv2_008433 Fc1ccc(CNC(=O)C2CCC(=O)N2C3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P08 compound treatment 0.245 0.0116 0.62 0.6247 1.0 1989300 ChemDiv2_008434 CC1CCC(CC1)NC(=O)c2ccc(CS(=O)(=O)Cc3cccc(Cl)c3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P09 compound treatment 0.311 0.0776 4.17 4.1714 1.0 1989301 ChemDiv2_008435 Cc1ccc(cc1)c2ccc(=O)n(CC(=O)NCc3ccccn3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P10 compound treatment 0.42 0.187 10.03 10.0288 1.0 1989302 ChemDiv2_008436 CC(C)NC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P11 compound treatment 0.385 0.152 8.15 8.148 1.0 1989303 ChemDiv2_008437 Cc1ccccc1CSCc2ccc(o2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P12 compound treatment 0.308 0.0746 4.01 4.0102 1.0 1989304 ChemDiv2_008438 COc1ccc(cc1)S(=O)(=O)Cc2ccc(o2)C(=O)NC3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P13 compound treatment 0.224 -0.00937 -0.5 -0.5038 -1.0 1989305 ChemDiv2_008439 O=C(C1CCC(=O)N1CCc2ccccc2)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P14 compound treatment 0.251 0.0176 0.95 0.9471 1.0 1989306 ChemDiv2_008440 CC(C)NC(=O)c1ccc(CS(=O)(=O)c2ccc(Br)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P15 compound treatment 0.227 -0.00637 -0.34 -0.3426 -1.0 1989307 ChemDiv2_008441 CCN1CCN(CC1)C(=O)C2CN(CCc3ccc(C)cc3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P16 compound treatment 0.285 0.0516 2.77 2.7742 1.0 1989308 ChemDiv2_008442 O=C(CSCCc1ccccn1)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P17 compound treatment 0.226 -0.00737 -0.4 -0.3963 -1.0 1989309 ChemDiv2_008443 CCS(=O)(=O)N1CCCC(C1)C(=O)NC(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P18 compound treatment 0.235 0.00162 0.09 0.0873 1.0 1989310 ChemDiv2_008444 Oc1c(C(=O)CCC2CCCC2)c(=O)oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P19 compound treatment 0.381 0.148 7.93 7.9331 1.0 1989311 ChemDiv2_008445 CNC(=O)c1cnn2c(O)c(Cc3ccccc3F)c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P20 compound treatment 0.246 0.0126 0.68 0.6784 1.0 1375920 ChemDiv2_008446 COc1ccc(NC(=O)CSc2nc3[nH]ncc3c(=O)n2c4ccc(C)c(Cl)c4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P21 compound treatment 0.249 0.0156 0.84 0.8397 1.0 1989312 ChemDiv2_008447 CCN1CCN(CC1)C(=O)c2cc(Nc3ccccc3)nc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P22 compound treatment 0.235 0.00162 0.09 0.0873 1.0 1331269 ChemDiv2_008448 CC1=C(C(C2=C(CCCC2=O)N1)c3ccsc3)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P23 mock treatment 0.223 -0.0104 -0.56 -0.5575 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1392 P24 mock treatment 0.235 0.00162 0.09 0.0873 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A01 compound treatment 0.232 0.00456 0.25 0.2453 1.0 1424067 ChemDiv2_008449 COc1cc(cc(OC)c1O)C2C(=C(C)NC3=C2C(=O)CC(C)(C)C3)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A02 mock treatment 0.236 0.00856 0.46 0.4602 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A03 compound treatment 0.243 0.0156 0.84 0.8364 1.0 1346095 ChemDiv2_008450 Oc1c(CC(=O)Nc2ccc(F)cc2)c(=O)[nH]c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A04 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A05 compound treatment 0.245 0.0176 0.94 0.9438 1.0 1331765 ChemDiv2_008451 Oc1cccc(NC(=O)C2CCCN2C(=O)OCc3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A06 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A07 compound treatment 0.464 0.237 12.71 12.7124 1.0 1514784 ChemDiv2_008452 COc1ccccc1n2cnc3cc(ccc23)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A08 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A09 compound treatment 0.355 0.128 6.86 6.855 1.0 1718899 ChemDiv2_008453 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(C)cc3)nc4[nH]nc(C)c4c2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A10 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A11 compound treatment 0.362 0.135 7.23 7.2312 1.0 1989313 ChemDiv2_008454 Cc1ccc(NC(=O)C2CCC(CNC(=O)c3ccc(=O)[nH]c3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A12 mock treatment 0.208 -0.0194 -1.04 -1.0445 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A13 compound treatment 0.305 0.0776 4.17 4.1681 1.0 1989314 ChemDiv2_008455 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)N3CCC(CC3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A14 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A15 compound treatment 0.255 0.0276 1.48 1.4812 1.0 1989315 ChemDiv2_008456 CC1CCCCN1S(=O)(=O)c2ccc3n(CC(=O)NC4CCCCCCC4)c(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A16 mock treatment 0.241 0.0136 0.73 0.7289 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A17 compound treatment 0.49 0.263 14.11 14.1096 1.0 1492557 ChemDiv2_008457 Cc1ccccc1OCc2nc(no2)c3ccc(NC(=O)c4ccco4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A18 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A19 compound treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1282339 ChemDiv2_008458 CCCNC(=O)Cn1cnc2sc(C(=O)NC(C)CC)c(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A20 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A21 compound treatment 0.25 0.0226 1.21 1.2125 1.0 1989316 ChemDiv2_008459 Cc1ccc(cc1)S(=O)(=O)CCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A22 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A23 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 A24 mock treatment 0.217 -0.0104 -0.56 -0.5608 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B01 compound treatment 0.26 0.0326 1.75 1.7499 1.0 1194521 ChemDiv2_008460 CCOC(=O)c1ccccc1NC(=O)c2nn(c3ccccc3OC)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B02 mock treatment 0.252 0.0246 1.32 1.32 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B03 compound treatment 0.541 0.314 16.85 16.8503 1.0 1989317 ChemDiv2_008461 CCCCN(CC)S(=O)(=O)c1ccc2oc(C(=O)O)c(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B04 mock treatment 0.247 0.0196 1.05 1.0513 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B05 compound treatment 0.486 0.259 13.89 13.8947 1.0 1297022 ChemDiv2_008462 O=C(NC1CC1)C2CN(C(=O)C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B06 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B07 compound treatment 0.453 0.226 12.12 12.1213 1.0 1199688 ChemDiv2_008463 CC(C)n1c2ccccc2c3nnc(SCC(=O)N4CCCCC4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B08 mock treatment 0.236 0.00856 0.46 0.4602 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B09 mock treatment 0.242 0.0146 0.78 0.7826 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B10 mock treatment 0.241 0.0136 0.73 0.7289 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B11 mock treatment 0.252 0.0246 1.32 1.32 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B12 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B13 mock treatment 0.233 0.00556 0.3 0.299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B14 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B15 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B16 mock treatment 0.246 0.0186 1.0 0.9976 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B17 mock treatment 0.238 0.0106 0.57 0.5677 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B18 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B19 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B20 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B21 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B22 mock treatment 0.217 -0.0104 -0.56 -0.5608 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B23 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 B24 mock treatment 0.206 -0.0214 -1.15 -1.1519 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C01 compound treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1143982 ChemDiv2_008464 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3)C(=O)N5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C02 mock treatment 0.24 0.0126 0.68 0.6752 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C03 compound treatment 0.236 0.00856 0.46 0.4602 1.0 1618355 ChemDiv2_008465 CC(C)NC(=O)Cc1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C04 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C05 compound treatment 0.244 0.0166 0.89 0.8901 1.0 1705637 ChemDiv2_008466 CN(Cc1ccccc1)C(=O)CNC(=O)Cn2cnc3sc(C)c(C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C06 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C07 compound treatment 0.554 0.327 17.55 17.5489 1.0 1655642 ChemDiv2_008467 COc1ccc(cc1)n2cnc3cc(ccc23)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C08 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C09 compound treatment 0.248 0.0206 1.11 1.1051 1.0 1514737 ChemDiv2_008468 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C10 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C11 compound treatment 0.326 0.0986 5.3 5.2966 1.0 1989318 ChemDiv2_008469 CCOc1ccc(NC(=O)C2CCC(CNC(=O)c3ccc(=O)[nH]c3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C12 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C13 compound treatment 0.278 0.0506 2.72 2.7172 1.0 1989319 ChemDiv2_008470 COc1ccc(cc1)N(CC(=O)O)S(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C14 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C15 compound treatment 0.424 0.197 10.56 10.5629 1.0 1989320 ChemDiv2_008471 CC1CCCN(C1)C(=O)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C16 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C17 compound treatment 0.428 0.201 10.78 10.7779 1.0 1989321 ChemDiv2_008472 Cc1ccccc1c2nc(no2)c3ccc(NC(=O)c4cccnc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C18 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C19 compound treatment 0.428 0.201 10.78 10.7779 1.0 1989322 ChemDiv2_008473 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCC2CCC(CC2)C(=O)N3CCC4(CC3)OCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C20 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C21 compound treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1989323 ChemDiv2_008474 COC(=O)c1cc(NC(=O)CCS(=O)(=O)c2ccc(Br)cc2)cc(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C22 mock treatment 0.22 -0.00744 -0.4 -0.3996 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C23 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 C24 mock treatment 0.233 0.00556 0.3 0.299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D01 compound treatment 0.325 0.0976 5.24 5.2429 1.0 1727057 ChemDiv2_008475 CCOc1ccc(cc1)n2nc(C(=O)Nc3cnc4ccccc4c3)c5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D02 mock treatment 0.244 0.0166 0.89 0.8901 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D03 compound treatment 0.257 0.0296 1.59 1.5887 1.0 1989324 ChemDiv2_008476 CC(N1C(=O)COc2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D04 mock treatment 0.24 0.0126 0.68 0.6752 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D05 compound treatment 0.25 0.0226 1.21 1.2125 1.0 1156347 ChemDiv2_008477 Clc1nc(NCc2cccnc2)nc(n1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D06 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D07 compound treatment 0.276 0.0486 2.61 2.6097 1.0 1636346 ChemDiv2_008478 CCn1cc(C(=O)NCCc2c(C)[nH]c3ccc(OC)cc23)c(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D08 mock treatment 0.245 0.0176 0.94 0.9438 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D09 mock treatment 0.247 0.0196 1.05 1.0513 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D10 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D11 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D12 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D13 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D14 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D15 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D16 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D17 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D18 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D19 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D20 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D21 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D22 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D23 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 D24 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E01 compound treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1357818 ChemDiv2_008479 COc1cc(ccc1OC(=O)C)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E02 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E03 compound treatment 0.316 0.0886 4.76 4.7592 1.0 1289185 ChemDiv2_008480 CCN(CC)c1ccc2cc(c3c(O)c4ccccc4[nH]c3=O)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E04 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E05 compound treatment 0.261 0.0336 1.8 1.8037 1.0 1989325 ChemDiv2_008481 Clc1nc(NCCN2CCOCC2)nc(Nc3ccc(I)cc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E06 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E07 compound treatment 0.255 0.0276 1.48 1.4812 1.0 1226364 ChemDiv2_008482 CN(c1ccccc1)c2ncnc3sc(C(=O)N4CCC5(CC4)OCCO5)c(C)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E08 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E09 compound treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1989326 ChemDiv2_008483 COc1ccc(CCNC(=O)Cn2c(=O)oc3ccccc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E10 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E11 compound treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1989327 ChemDiv2_008484 Cc1nn(C)c(C)c1S(=O)(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E12 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E13 compound treatment 0.237 0.00956 0.51 0.5139 1.0 1989328 ChemDiv2_008485 CC(N(c1ccc(C)cc1)S(=O)(=O)c2cccnc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E14 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E15 compound treatment 0.388 0.161 8.63 8.6284 1.0 1989329 ChemDiv2_008486 O=C(NCc1cccs1)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E16 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E17 compound treatment 0.525 0.298 15.99 15.9905 1.0 1989330 ChemDiv2_008487 O=C(Nc1ccc(cc1)c2noc(n2)c3cccs3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E18 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E19 compound treatment 0.345 0.118 6.32 6.3176 1.0 1989331 ChemDiv2_008488 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCC2CCC(CC2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E20 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E21 compound treatment 0.274 0.0466 2.5 2.5022 1.0 1989332 ChemDiv2_008489 CN(Cc1ccccc1)C(=O)CCS(=O)(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E22 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E23 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 E24 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F01 compound treatment 0.239 0.0116 0.62 0.6214 1.0 1695925 ChemDiv2_008490 CCOc1ccc(cc1)n2nc(C(=O)NC(C)C)c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F02 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F03 compound treatment 0.25 0.0226 1.21 1.2125 1.0 1989333 ChemDiv2_008491 CCC(N1C(=O)COc2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F04 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F05 compound treatment 0.251 0.0236 1.27 1.2663 1.0 1636475 ChemDiv2_008492 Cc1ccccc1N(CC(=O)N2CCOCC2)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F06 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F07 compound treatment 0.234 0.00656 0.35 0.3527 1.0 1519307 ChemDiv2_008493 COc1ccc(cc1OC)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5cccs5)C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F08 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F09 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F10 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F11 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F12 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F13 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F14 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F15 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F16 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F17 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F18 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F19 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F20 mock treatment 0.212 -0.0154 -0.83 -0.8295 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F21 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F22 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F23 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 F24 mock treatment 0.206 -0.0214 -1.15 -1.1519 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G01 compound treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1701949 ChemDiv2_008494 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccccc3F)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G02 mock treatment 0.241 0.0136 0.73 0.7289 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G03 compound treatment 0.264 0.0366 1.96 1.9649 1.0 1169014 ChemDiv2_008495 CC1CCCCN1C(=O)Cn2cnc3sc(C(=O)NCc4cccnc4)c(C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G04 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G05 compound treatment 0.286 0.0586 3.15 3.1471 1.0 1989334 ChemDiv2_008496 OCCNc1nc(Nc2ccc(I)cc2)nc(n1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G06 mock treatment 0.216 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G07 compound treatment 0.274 0.0466 2.5 2.5022 1.0 1296044 ChemDiv2_008497 Cc1n[nH]c2nc(SCC(=O)NCc3ccccc3)n(c4ccccc4C)c(=N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G08 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G09 compound treatment 0.342 0.115 6.16 6.1564 1.0 1371564 ChemDiv2_008498 CCOC(=O)Cc1csc(NC(=O)Cn2c(=O)oc3ccccc23)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G10 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G11 compound treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1989335 ChemDiv2_008499 O=S(=O)(NCc1ccccc1)c2c[nH]cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G12 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G13 compound treatment 0.231 0.00356 0.19 0.1915 1.0 1989336 ChemDiv2_008500 OC(=O)C(NS(=O)(=O)c1cccc2cccnc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G14 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G15 compound treatment 0.455 0.228 12.23 12.2288 1.0 1989337 ChemDiv2_008501 CC1CCCC(NC(=O)c2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2)C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G16 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G17 compound treatment 0.488 0.261 14.0 14.0022 1.0 1989338 ChemDiv2_008502 O=C(Nc1ccc(cc1)c2noc(CCc3ccccc3)n2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G18 mock treatment 0.22 -0.00744 -0.4 -0.3996 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G19 compound treatment 0.302 0.0746 4.01 4.0069 1.0 1989339 ChemDiv2_008503 CCC(C)NC(=O)C1CCC(CNS(=O)(=O)c2ccc(NC(=O)C)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G20 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G21 compound treatment 0.458 0.231 12.39 12.39 1.0 1989340 ChemDiv2_008504 CCOC(=O)c1ccc(NC(=O)CCS(=O)(=O)c2ccc(OC)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G22 mock treatment 0.215 -0.0124 -0.67 -0.6683 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G23 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 G24 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H01 compound treatment 0.249 0.0216 1.16 1.1588 1.0 1230210 ChemDiv2_008505 COc1ccc(c(OC)c1)n2nc(C(=O)N(C)C3CCCCC3)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H02 mock treatment 0.242 0.0146 0.78 0.7826 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H03 compound treatment 0.237 0.00956 0.51 0.5139 1.0 1989341 ChemDiv2_008506 CC1Oc2ccccc2N(CC(=O)O)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H04 mock treatment 0.245 0.0176 0.94 0.9438 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H05 compound treatment 0.42 0.193 10.35 10.348 1.0 1472282 ChemDiv2_008507 O=C(CSCc1ccccc1)Nc2nnc(CSCc3ccccc3)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H06 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H07 compound treatment 0.464 0.237 12.71 12.7124 1.0 1503365 ChemDiv2_008508 CCOC(=O)c1[nH]c(C)c(CN(Cc2ccccc2)S(=O)(=O)CC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H08 mock treatment 0.232 0.00456 0.25 0.2453 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H09 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H10 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H11 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H12 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H13 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H14 mock treatment 0.22 -0.00744 -0.4 -0.3996 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H15 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H16 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H17 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H18 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H19 mock treatment 0.212 -0.0154 -0.83 -0.8295 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H20 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H21 mock treatment 0.215 -0.0124 -0.67 -0.6683 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H22 mock treatment 0.215 -0.0124 -0.67 -0.6683 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H23 mock treatment 0.204 -0.0234 -1.26 -1.2594 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 H24 mock treatment 0.212 -0.0154 -0.83 -0.8295 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I01 compound treatment 0.31 0.0826 4.44 4.4368 1.0 1169010 ChemDiv2_008509 Cc1cccc(NC(=O)c2ccccc2NC(=O)c3cccc(c3)S(=O)(=O)N4CCOCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I02 mock treatment 0.242 0.0146 0.78 0.7826 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I03 compound treatment 0.229 0.00156 0.08 0.084 1.0 1989342 ChemDiv2_008510 Cn1nc(CC(=O)NC2CCCCCC2)c3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I04 mock treatment 0.232 0.00456 0.25 0.2453 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I05 compound treatment 0.286 0.0586 3.15 3.1471 1.0 1467572 ChemDiv2_008511 CC1CCN(CC1)C(=O)c2sc3ncn(CC(=O)Nc4ccc(C)c(Cl)c4)c(=O)c3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I06 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I07 compound treatment 0.233 0.00556 0.3 0.299 1.0 1989343 ChemDiv2_008512 CCC(Sc1nc2[nH]nc(C)c2c(=N)n1c3ccccc3C)C(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I08 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I09 compound treatment 0.299 0.0716 3.85 3.8457 1.0 1989344 ChemDiv2_008513 COc1ccc(OC)c(NC(=O)Cn2c(=O)oc3cc(Cl)ccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I10 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I11 compound treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1458316 ChemDiv2_008514 OC(=O)C(NS(=O)(=O)c1cccc2nsnc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I12 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I13 compound treatment 0.242 0.0146 0.78 0.7826 1.0 1989345 ChemDiv2_008515 OC(=O)C1CCCN1S(=O)(=O)c2ccc3NC(=O)CCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I14 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I15 compound treatment 0.433 0.206 11.05 11.0466 1.0 1989346 ChemDiv2_008516 CCOC(=O)c1cc(c2ccc(F)cc2)n(CC(=O)Nc3nccs3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I16 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I17 compound treatment 0.456 0.229 12.28 12.2825 1.0 1989347 ChemDiv2_008517 Brc1ccccc1c2nc(no2)c3ccc(NC(=O)c4cccnc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I18 mock treatment 0.233 0.00556 0.3 0.299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I19 compound treatment 0.443 0.216 11.58 11.584 1.0 1989348 ChemDiv2_008518 COC(=O)c1ccc(NC(=O)C2CCCN2C(=O)OCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I20 mock treatment 0.209 -0.0184 -0.99 -0.9907 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I21 compound treatment 0.253 0.0256 1.37 1.3738 1.0 1989349 ChemDiv2_008519 COc1ccc(cc1)S(=O)(=O)CCC(=O)N(C)c2cc(C)ccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I22 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I23 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 I24 mock treatment 0.216 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J01 compound treatment 0.271 0.0436 2.34 2.341 1.0 1545932 ChemDiv2_008520 COc1cc(OC)cc(c1)n2nc(C(=O)NCc3ccccc3OC)c4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J02 mock treatment 0.24 0.0126 0.68 0.6752 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J03 compound treatment 0.246 0.0186 1.0 0.9976 1.0 1989350 ChemDiv2_008521 CC(N1C(=O)C(C)Oc2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J04 mock treatment 0.244 0.0166 0.89 0.8901 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J05 compound treatment 0.51 0.283 15.18 15.1844 1.0 1227044 ChemDiv2_008522 C(Sc1ncnc2[nH]cnc12)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J06 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J07 compound treatment 0.321 0.0936 5.03 5.0279 1.0 1463706 ChemDiv2_008523 CN(C)S(=O)(=O)c1cc(C(=O)NCc2ccncc2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J08 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J09 mock treatment 0.24 0.0126 0.68 0.6752 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J10 mock treatment 0.238 0.0106 0.57 0.5677 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J11 mock treatment 0.245 0.0176 0.94 0.9438 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J12 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J13 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J14 mock treatment 0.22 -0.00744 -0.4 -0.3996 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J15 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J16 mock treatment 0.233 0.00556 0.3 0.299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J17 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J18 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J19 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J20 mock treatment 0.21 -0.0174 -0.94 -0.937 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J21 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J22 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J23 mock treatment 0.211 -0.0164 -0.88 -0.8832 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 J24 mock treatment 0.205 -0.0224 -1.21 -1.2057 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K01 compound treatment 0.262 0.0346 1.86 1.8574 1.0 1438367 ChemDiv2_008524 CCOC(=O)CNc1ncnc2scc(c3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K02 mock treatment 0.249 0.0216 1.16 1.1588 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K03 compound treatment 0.264 0.0366 1.96 1.9649 1.0 1198168 ChemDiv2_008525 COc1ccc(CNC(=O)Cc2nn(C)c(=O)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K04 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K05 compound treatment 0.426 0.199 10.67 10.6704 1.0 1715152 ChemDiv2_008526 O=c1[nH]c2ccc(cc2o1)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K06 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K07 compound treatment 0.391 0.164 8.79 8.7896 1.0 1508553 ChemDiv2_008527 COc1cccc(c1)n2c(SCC(=O)N3CC(C)CC(C)C3)nc4[nH]nc(C)c4c2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K08 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K09 compound treatment 0.239 0.0116 0.62 0.6214 1.0 1204787 ChemDiv2_008528 Cc1cc2c(=O)n(CC(=O)N3CCCCCC3)cnc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K10 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K11 compound treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1989351 ChemDiv2_008529 COc1ccc(cc1)N(CC(=O)O)S(=O)(=O)c2c(C)noc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K12 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K13 compound treatment 0.28 0.0526 2.82 2.8247 1.0 1989352 ChemDiv2_008530 COc1cccc(c1)C(=O)N2CCN(C(=O)c3ccc(F)cc3)c4ccccc4C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K14 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K15 compound treatment 0.4 0.173 9.27 9.2732 1.0 1989353 ChemDiv2_008531 CCOC(=O)c1cccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCC4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K16 mock treatment 0.232 0.00456 0.25 0.2453 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K17 compound treatment 0.42 0.193 10.35 10.348 1.0 1989354 ChemDiv2_008532 CC(Oc1ccc(Cl)cc1Cl)c2nc(no2)c3ccc(NC(=O)c4cccnc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K18 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K19 compound treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1643012 ChemDiv2_008533 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)N4CCc5ccccc5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K20 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K21 compound treatment 0.217 -0.0104 -0.56 -0.5608 -1.0 1989355 ChemDiv2_008534 O=C(CNC(=O)Cn1cnc2ccccc2c1=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K22 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K23 mock treatment 0.211 -0.0164 -0.88 -0.8832 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 K24 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L01 compound treatment 0.249 0.0216 1.16 1.1588 1.0 1666462 ChemDiv2_008535 CCCn1cnc2n(C)c(=O)[nH]c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L02 mock treatment 0.24 0.0126 0.68 0.6752 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L03 compound treatment 0.249 0.0216 1.16 1.1588 1.0 1989356 ChemDiv2_008536 COCc1cc(nc(N)n1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L04 mock treatment 0.241 0.0136 0.73 0.7289 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L05 compound treatment 0.36 0.133 7.12 7.1237 1.0 1915354 ChemDiv2_008537 Cc1nc2nc(cn2nc1C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L06 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L07 compound treatment 0.335 0.108 5.78 5.7803 1.0 1423519 ChemDiv2_008538 CN(C)S(=O)(=O)c1cc(C(=O)NCc2ccco2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L08 mock treatment 0.237 0.00956 0.51 0.5139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L09 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L10 mock treatment 0.232 0.00456 0.25 0.2453 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L11 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L12 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L13 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L14 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L15 mock treatment 0.236 0.00856 0.46 0.4602 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L16 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L17 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L18 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L19 mock treatment 0.214 -0.0134 -0.72 -0.722 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L20 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L21 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L22 mock treatment 0.213 -0.0144 -0.78 -0.7758 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L23 mock treatment 0.216 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 L24 mock treatment 0.207 -0.0204 -1.1 -1.0982 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M01 compound treatment 0.254 0.0266 1.43 1.4275 1.0 1730870 ChemDiv2_008539 Cc1ccc(NC(=O)Cc2c(O)c3ccccc3[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M02 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M03 compound treatment 0.229 0.00156 0.08 0.084 1.0 1624115 ChemDiv2_008540 Cn1nc(CC(=O)N2CCN(CC2)c3ccccc3)c4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M04 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M05 compound treatment 0.233 0.00556 0.3 0.299 1.0 1775743 ChemDiv2_008541 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M06 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M07 compound treatment 0.375 0.148 7.93 7.9298 1.0 1346895 ChemDiv2_008542 Cc1n[nH]c2nc(SCC(=O)NCCc3ccccc3)n(c4cccc(C)c4)c(=N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M08 mock treatment 0.221 -0.00644 -0.35 -0.3459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M09 compound treatment 0.263 0.0356 1.91 1.9111 1.0 1989357 ChemDiv2_008543 COc1ccc(CC(=O)N2CC(=O)N(CCc3ccccc3)C(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M10 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M11 compound treatment 0.23 0.00256 0.14 0.1378 1.0 1989358 ChemDiv2_008544 Cc1noc(C)c1S(=O)(=O)N(CC(=O)O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M12 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M13 compound treatment 0.245 0.0176 0.94 0.9438 1.0 1989359 ChemDiv2_008545 O=C(N1CCNc2ccccc2C1)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M14 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M15 compound treatment 0.257 0.0296 1.59 1.5887 1.0 1989360 ChemDiv2_008546 CCOC(=O)c1ccc(NC(=O)Cn2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M16 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M17 compound treatment 0.294 0.0666 3.58 3.577 1.0 1657079 ChemDiv2_008547 CCOc1ccc(cc1)N(C)S(=O)(=O)c2ccc3[nH]cc(C(=O)NCC=C)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M18 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M19 compound treatment 0.228 5.64E-4 0.03 0.0303 1.0 1433192 ChemDiv2_008548 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)N4CCN(Cc5ccccc5)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M20 mock treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M21 compound treatment 0.219 -0.00844 -0.45 -0.4533 -1.0 1315086 ChemDiv2_008549 COc1cccc(NC(=O)c2nn(c3cccc(OC)c3)c(=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M22 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M23 mock treatment 0.212 -0.0154 -0.83 -0.8295 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 M24 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N01 compound treatment 0.248 0.0206 1.11 1.1051 1.0 1475530 ChemDiv2_008550 Cc1cc(C)nc(NCCO)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N02 mock treatment 0.253 0.0256 1.37 1.3738 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N03 compound treatment 0.241 0.0136 0.73 0.7289 1.0 1989361 ChemDiv2_008551 COc1nc(N)nc(CC(=O)C2CC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N04 mock treatment 0.241 0.0136 0.73 0.7289 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N05 compound treatment 0.25 0.0226 1.21 1.2125 1.0 1279286 ChemDiv2_008552 Cn1c(=N)n(CC(=O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N06 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N07 mock treatment 0.234 0.00656 0.35 0.3527 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N08 mock treatment 0.241 0.0136 0.73 0.7289 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N09 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N10 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N11 mock treatment 0.24 0.0126 0.68 0.6752 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N12 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N13 mock treatment 0.238 0.0106 0.57 0.5677 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N14 mock treatment 0.229 0.00156 0.08 0.084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N15 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N16 mock treatment 0.233 0.00556 0.3 0.299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N17 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N18 mock treatment 0.217 -0.0104 -0.56 -0.5608 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N19 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N20 mock treatment 0.214 -0.0134 -0.72 -0.722 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N21 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N22 mock treatment 0.216 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N23 mock treatment 0.217 -0.0104 -0.56 -0.5608 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 N24 mock treatment 0.206 -0.0214 -1.15 -1.1519 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O01 compound treatment 0.235 0.00756 0.41 0.4065 1.0 1495944 ChemDiv2_008553 Oc1c(CC(=O)NC2CCCCCCC2)c(=O)[nH]c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O02 mock treatment 0.238 0.0106 0.57 0.5677 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O03 compound treatment 0.312 0.0846 4.54 4.5443 1.0 1650893 ChemDiv2_008554 O=C(CCS(=O)(=O)c1ccccc1)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O04 mock treatment 0.232 0.00456 0.25 0.2453 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O05 compound treatment 0.494 0.267 14.32 14.3246 1.0 1639448 ChemDiv2_008555 COc1ccccc1n2cnc3cc(ccc23)C(=O)NCc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O06 mock treatment 0.238 0.0106 0.57 0.5677 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O07 compound treatment 0.356 0.129 6.91 6.9088 1.0 1633975 ChemDiv2_008556 Cc1n[nH]c2nc(SCC(=O)Nc3cccc(C)c3)n(c4cccc(C)c4)c(=N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O08 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O09 compound treatment 0.235 0.00756 0.41 0.4065 1.0 1989362 ChemDiv2_008557 Cc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O10 mock treatment 0.231 0.00356 0.19 0.1915 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O11 compound treatment 0.305 0.0776 4.17 4.1681 1.0 1989363 ChemDiv2_008558 CC(NS(=O)(=O)c1ccc2n(C)c(=O)n(C)c(=O)c2c1)C(=O)N3CCN(CC3)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O12 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O13 compound treatment 0.24 0.0126 0.68 0.6752 1.0 1989364 ChemDiv2_008559 CN(CC(=O)Nc1ccc(F)cc1)S(=O)(=O)c2c(C)noc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O14 mock treatment 0.235 0.00756 0.41 0.4065 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O15 compound treatment 0.252 0.0246 1.32 1.32 1.0 1989365 ChemDiv2_008560 Nc1ncc(Br)cc1S(=O)(=O)Nc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O16 mock treatment 0.239 0.0116 0.62 0.6214 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O17 compound treatment 0.234 0.00656 0.35 0.3527 1.0 1485680 ChemDiv2_008561 CCCN(CCC)C(=O)c1c[nH]c2ccc(cc2c1=O)S(=O)(=O)N(C)c3ccccc3OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O18 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O19 compound treatment 0.229 0.00156 0.08 0.084 1.0 1628120 ChemDiv2_008562 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O20 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O21 compound treatment 0.217 -0.0104 -0.56 -0.5608 -1.0 1663953 ChemDiv2_008563 CCOc1ccc(NC(=O)c2nn(c3ccccc3OC)c(=O)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O22 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O23 mock treatment 0.22 -0.00744 -0.4 -0.3996 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 O24 mock treatment 0.227 -4.36E-4 -0.02 -0.0234 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P01 compound treatment 0.33 0.103 5.51 5.5116 1.0 1989366 ChemDiv2_008564 CN(c1ccc(F)cc1)S(=O)(=O)c2ccc3[nH]cc(C(=O)O)c(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P02 mock treatment 0.246 0.0186 1.0 0.9976 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P03 compound treatment 0.262 0.0346 1.86 1.8574 1.0 1989367 ChemDiv2_008565 CCn1c(=O)n(CC)c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P04 mock treatment 0.224 -0.00344 -0.18 -0.1846 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P05 compound treatment 0.243 0.0156 0.84 0.8364 1.0 1506259 ChemDiv2_008566 CCC1(CC)OC(Nc2ccccc21)c3ccc(NC(=O)C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P06 mock treatment 0.23 0.00256 0.14 0.1378 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P07 mock treatment 0.238 0.0106 0.57 0.5677 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P08 mock treatment 0.226 -0.00144 -0.08 -0.0772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P09 mock treatment 0.228 5.64E-4 0.03 0.0303 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P10 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P11 mock treatment 0.216 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P12 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P13 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P14 mock treatment 0.225 -0.00244 -0.13 -0.1309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P15 mock treatment 0.22 -0.00744 -0.4 -0.3996 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P16 mock treatment 0.218 -0.00944 -0.51 -0.5071 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P17 mock treatment 0.215 -0.0124 -0.67 -0.6683 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P18 mock treatment 0.213 -0.0144 -0.78 -0.7758 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P19 mock treatment 0.232 0.00456 0.25 0.2453 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P20 mock treatment 0.214 -0.0134 -0.72 -0.722 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P21 mock treatment 0.216 -0.0114 -0.61 -0.6146 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P22 mock treatment 0.223 -0.00444 -0.24 -0.2384 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P23 mock treatment 0.222 -0.00544 -0.29 -0.2921 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1393 P24 mock treatment 0.214 -0.0134 -0.72 -0.722 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A01 compound treatment 0.297 0.0553 2.97 2.9741 1.0 1083875 Enamine_000001 Fc1ccc(cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A02 compound treatment 0.244 0.00234 0.13 0.1259 1.0 1514114 Enamine_000002 CC1(C)CC(=O)C=C(C1)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A03 compound treatment 0.304 0.0623 3.35 3.3502 1.0 1465612 Enamine_000003 O=C(NCc1ccccc1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A04 compound treatment 0.506 0.264 14.21 14.2053 1.0 2060505 Enamine_000004 c1coc(c1)c2nnc(o2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A05 compound treatment 0.274 0.0323 1.74 1.7381 1.0 2060506 Enamine_000005 CC(C)C1Nc2ccc(cc2NC1=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A06 compound treatment 0.393 0.151 8.13 8.1329 1.0 2060507 Enamine_000006 Oc1n[n+](nn1c2cccc(Cl)c2)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A07 compound treatment 0.234 -0.00766 -0.41 -0.4114 -1.0 1334319 Enamine_000007 CC(C)(C)N=c1scc(c2ccccc2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A08 compound treatment 0.537 0.295 15.87 15.8712 1.0 2060508 Enamine_000008 CC1(C)CC(=O)c2sc(NC(=O)/C=C/c3ccccc3)nc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A09 compound treatment 0.249 0.00734 0.39 0.3946 1.0 1194594 Enamine_000009 CC1=CC(c2ccccc2)n3nc(N)nc3N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A10 compound treatment 0.245 0.00334 0.18 0.1797 1.0 1160416 Enamine_000010 CC1CN(CC(O)COCc2ccccc2CC=C)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A11 compound treatment 0.357 0.115 6.2 6.1983 1.0 2060509 Enamine_000011 ClCCCC(=O)Nc1sc2CCCc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A12 compound treatment 0.472 0.23 12.38 12.3782 1.0 1322575 Enamine_000012 CCc1ccc(OCC(=O)N(C)C2CCS(=O)(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A13 compound treatment 0.367 0.125 6.74 6.7357 1.0 1179006 Enamine_000013 COC(=O)c1cccc(CSc2nc3ccccc3[nH]2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A14 compound treatment 0.507 0.265 14.26 14.259 1.0 1287987 Enamine_000014 COc1ccc2[nH]c(=NC(=O)c3ccc(Br)cc3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A15 compound treatment 0.245 0.00334 0.18 0.1797 1.0 2060510 Enamine_000015 Cc1n[nH]c(C)c1c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A16 compound treatment 0.242 3.44E-4 0.02 0.0185 1.0 2060511 Enamine_000016 FC(F)(F)S(=O)(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A17 compound treatment 0.251 0.00934 0.5 0.5021 1.0 1914550 Enamine_000017 C(Nn1cn[n+](Cc2ccccc2)c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A18 compound treatment 0.331 0.0893 4.8 4.8011 1.0 2060512 Enamine_000018 Brc1ccc(cc1)c2csc(CC#N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A19 compound treatment 0.262 0.0203 1.09 1.0932 1.0 1537252 Enamine_000019 CC1Cc2ccccc2N1C(=O)C3(CCCC3)S(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A20 compound treatment 0.252 0.0103 0.56 0.5559 1.0 2060513 Enamine_000020 CC(=O)Nc1cccc2nc(C)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A21 compound treatment 0.242 3.44E-4 0.02 0.0185 1.0 2060514 Enamine_000021 Brc1ccc(NC2=Nc3ccccc3CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A22 compound treatment 0.247 0.00534 0.29 0.2872 1.0 1513176 Enamine_000022 CC(C)(C)c1cc(cc(c1)C(C)(C)C)C(=O)N(CCO)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A23 mock treatment 0.246 0.00434 0.23 0.2334 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 A24 mock treatment 0.258 0.0163 0.88 0.8783 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B01 compound treatment 0.239 -0.00266 -0.14 -0.1427 -1.0 2060515 Enamine_000023 CN1/C(=C/C=N/O)/C(C)(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B02 compound treatment 0.268 0.0263 1.42 1.4157 1.0 1363536 Enamine_000024 Cc1nc2ccc(cc2s1)n3ccc(=O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B03 compound treatment 0.253 0.0113 0.61 0.6096 1.0 2060516 Enamine_000025 COc1ccc(cc1)[N+]2=C3CCc4ccccc4N3CC2(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B04 compound treatment 0.25 0.00834 0.45 0.4484 1.0 2060517 Enamine_000026 CCN1CCN(CC1)C(=O)CC2(OCCO2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B05 compound treatment 0.393 0.151 8.13 8.1329 1.0 2060518 Enamine_000027 O/C(=N\c1nc2CCCCc2s1)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B06 compound treatment 0.317 0.0753 4.05 4.0488 1.0 2060519 Enamine_000028 Brc1ccc(o1)C(=O)Nc2ccccc2I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B07 compound treatment 0.516 0.274 14.74 14.7427 1.0 1590083 Enamine_000029 COC(=O)c1ccc(NC(=O)COc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B08 compound treatment 0.249 0.00734 0.39 0.3946 1.0 2060520 Enamine_000030 CC(CCC(=O)O)C1CCC2C3CCC4C[C@H](O)CCC4(C)C3CC(=O)C12C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B09 compound treatment 0.42 0.178 9.58 9.5838 1.0 1710139 Enamine_000031 O=C(N=c1nc2ccccn2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B10 compound treatment 0.274 0.0323 1.74 1.7381 1.0 2060521 Enamine_000032 Cc1csc(CC(=O)N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B11 compound treatment 0.481 0.239 12.86 12.8618 1.0 1247425 Enamine_000033 CN(C1CCS(=O)(=O)C1)C(=O)COc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B12 compound treatment 0.474 0.232 12.49 12.4857 1.0 1215332 Enamine_000034 CC1=CC(C)(C)Nc2ccc(OC(=O)c3ccc(Cl)cc3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B13 compound treatment 0.25 0.00834 0.45 0.4484 1.0 2060522 Enamine_000035 COc1ccc(cc1)N2C3=[N+](CC2(O)c4ccccc4)CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B14 compound treatment 0.607 0.365 19.63 19.6328 1.0 2060523 Enamine_000036 CCN1/C(=C\C=C\C(=O)c2ccccc2OC)/Sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B15 compound treatment 0.308 0.0663 3.57 3.5652 1.0 2060524 Enamine_000037 Cc1ccc(cc1)/C(=N/c2nc3CCCCc3s2)/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B16 compound treatment 0.261 0.0193 1.04 1.0395 1.0 2060525 Enamine_000038 CN1C/C(=C\c2ccccn2)/C(=O)\C(=C/c3ccccn3)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B17 compound treatment 0.244 0.00234 0.13 0.1259 1.0 2060526 Enamine_000039 CC(C)N1C(SCC1=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B18 compound treatment 0.457 0.215 11.57 11.5721 1.0 1519734 Enamine_000040 COc1ccc2c(c1)oc(=O)c3ccccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B19 compound treatment 0.243 0.00134 0.07 0.0722 1.0 2060527 Enamine_000041 NC(=O)c1cc2ccccc2oc1=Nc3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B20 compound treatment 0.315 0.0733 3.94 3.9413 1.0 2060528 Enamine_000042 OC(c1ccc(NC(=O)COc2ccccc2)cc1)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B21 compound treatment 0.243 0.00134 0.07 0.0722 1.0 2060529 Enamine_000043 OC(=O)CC1CS(=O)(=O)C(=C1)Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B22 compound treatment 0.232 -0.00966 -0.52 -0.5189 -1.0 1416354 Enamine_000044 CC(C)COc1ccc(N)cc1OCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B23 mock treatment 0.227 -0.0147 -0.79 -0.7876 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 B24 mock treatment 0.23 -0.0117 -0.63 -0.6264 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C01 compound treatment 0.254 0.0123 0.66 0.6633 1.0 2060530 Enamine_000045 CCN1C(=O)c2cccc3c(Cl)cc(Cl)c1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C02 compound treatment 0.273 0.0313 1.68 1.6843 1.0 2060531 Enamine_000046 N#C/C(=C\1/CCCCCN1)/c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C03 compound treatment 0.245 0.00334 0.18 0.1797 1.0 1026531 Enamine_000047 Cc1ccc(cc1)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C04 compound treatment 0.277 0.0353 1.9 1.8993 1.0 2060532 Enamine_000048 Cc1nc2cc(ccc2n1C)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C05 compound treatment 0.256 0.0143 0.77 0.7708 1.0 1020452 Enamine_000049 Cc1ccccc1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C06 compound treatment 0.259 0.0173 0.93 0.932 1.0 2060533 Enamine_000050 O=S(=O)(c1ccccc1)C2(CCCC2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C07 compound treatment 0.357 0.115 6.2 6.1983 1.0 1189587 Enamine_000051 COc1ccccc1N=c2[nH]c(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C08 compound treatment 0.301 0.0593 3.19 3.189 1.0 2060534 Enamine_000052 Cn1ccnc1C(=O)c2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C09 compound treatment 0.496 0.254 13.67 13.6679 1.0 1316979 Enamine_000053 COc1ccc2cc(c3nc4ccccc4[nH]3)c(=N)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C10 compound treatment 0.361 0.119 6.41 6.4133 1.0 2060535 Enamine_000054 O=C(Sc1cccc2cccnc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C11 compound treatment 0.256 0.0143 0.77 0.7708 1.0 2060536 Enamine_000055 CC12CCC3C(CCC4C[C@H](O)CCC43C)C2CCC1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C12 compound treatment 0.446 0.204 10.98 10.981 1.0 1261830 Enamine_000056 CCOc1ccc2[nH]c(=NC(=O)C(C)C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C13 compound treatment 0.303 0.0613 3.3 3.2965 1.0 1087624 Enamine_000057 CN(C)C(=S)SCC(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C14 compound treatment 0.519 0.277 14.9 14.9039 1.0 2060537 Enamine_000058 CCN(CC)C(=O)COc1ccc(CC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C15 compound treatment 0.253 0.0113 0.61 0.6096 1.0 2060538 Enamine_000059 Cn1c(COc2ccccc2O)[n+](C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C16 compound treatment 0.304 0.0623 3.35 3.3502 1.0 2060539 Enamine_000060 Cc1ccc(NC(=O)Cc2cccs2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C17 compound treatment 0.328 0.0863 4.64 4.6399 1.0 1467148 Enamine_000061 CC(C)C(C(=O)Nc1nccs1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C18 compound treatment 0.255 0.0133 0.72 0.7171 1.0 2060540 Enamine_000062 C(=N/c1ncccn1)\c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C19 compound treatment 0.465 0.223 12.0 12.002 1.0 1611874 Enamine_000063 CCOc1ccc2[nH]c(=NC(=O)c3ccc(cc3)C(C)(C)C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C20 compound treatment 0.325 0.0833 4.48 4.4787 1.0 1534951 Enamine_000064 N#CCc1nc(cs1)c2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C21 compound treatment 0.416 0.174 9.37 9.3689 1.0 1032906 Enamine_000065 Oc1ccc(Br)cc1c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C22 compound treatment 0.259 0.0173 0.93 0.932 1.0 1430435 Enamine_000066 O=C(CNc1ccncc1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C23 mock treatment 0.245 0.00334 0.18 0.1797 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 C24 mock treatment 0.237 -0.00466 -0.25 -0.2502 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D01 compound treatment 0.24 -0.00166 -0.09 -0.089 -1.0 2060541 Enamine_000067 Nc1ccc(/C=C\C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D02 compound treatment 0.245 0.00334 0.18 0.1797 1.0 1677572 Enamine_000068 Oc1ccccc1C(=O)Nc2nc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D03 compound treatment 0.309 0.0673 3.62 3.6189 1.0 1244157 Enamine_000069 Cc1cc2ccccn2c1C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D04 compound treatment 0.267 0.0253 1.36 1.3619 1.0 1395295 Enamine_000070 Cc1nc2cc(ccc2n1c3ccccc3)n4c(C)cc(=O)cc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D05 compound treatment 0.42 0.178 9.58 9.5838 1.0 1604713 Enamine_000071 Nc1nc2NC(=CC(c3ccc(Br)cc3)n2n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D06 compound treatment 0.282 0.0403 2.17 2.168 1.0 1499966 Enamine_000072 Clc1ccc(cc1)C(=O)N(Cc2ccccc2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D07 compound treatment 0.264 0.0223 1.2 1.2007 1.0 1043897 Enamine_000073 CC(=O)Nc1ccc2oc(=O)ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D08 compound treatment 0.278 0.0363 1.95 1.953 1.0 1727371 Enamine_000074 CC(=O)Nc1c(C#N)c2nc3ccccc3nc2n1C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D09 compound treatment 0.235 -0.00666 -0.36 -0.3577 -1.0 1628396 Enamine_000075 COC(=O)NC1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D10 compound treatment 0.484 0.242 13.02 13.023 1.0 2060542 Enamine_000076 CC(C)(C)c1csc(NC(=O)/C=C/c2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D11 compound treatment 0.273 0.0313 1.68 1.6843 1.0 1706368 Enamine_000077 Cc1nn(c2ccccc2)c3nc(O)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D12 compound treatment 0.291 0.0493 2.65 2.6516 1.0 1741266 Enamine_000078 COc1ccc2c(C)cc3nncn3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D13 compound treatment 0.178 -0.0637 -3.42 -3.4208 -1.0 1463660 Enamine_000079 CC(C)(C)c1ccc(O)c(c1O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D14 compound treatment 0.29 0.0483 2.6 2.5979 1.0 2060543 Enamine_000080 CC(C)CCSc1nc2ncn(C)c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D15 compound treatment 0.288 0.0463 2.49 2.4904 1.0 2060544 Enamine_000081 Cc1ccc2nc(/N=C(\O)/C=C/c3ccccc3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D16 compound treatment 0.391 0.149 8.03 8.0254 1.0 2060545 Enamine_000082 O/N=C/1\CCC\C1=C/c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D17 compound treatment 0.243 0.00134 0.07 0.0722 1.0 1120321 Enamine_000083 CC(=O)Nc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D18 compound treatment 0.583 0.341 18.34 18.3431 1.0 2060546 Enamine_000084 Oc1ccc2ccccc2c1/C=N/Cc3cn4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D19 compound treatment 0.247 0.00534 0.29 0.2872 1.0 2060547 Enamine_000085 CC(C)C(Nc1ccc(cc1Cl)C(F)(F)F)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D20 compound treatment 0.285 0.0433 2.33 2.3292 1.0 2060548 Enamine_000086 c1[nH]nc(c1c2nc3ccccc3[nH]2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D21 compound treatment 0.35 0.108 5.82 5.8222 1.0 1592397 Enamine_000087 C1CCC(=Nc2nc(Nc3ccccc3)cs2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D22 compound treatment 0.246 0.00434 0.23 0.2334 1.0 2060549 Enamine_000088 CC(C)(Oc1ccccc1OC(=O)c2ccccc2)C(=O)CBr 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D23 mock treatment 0.229 -0.0127 -0.68 -0.6801 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 D24 mock treatment 0.232 -0.00966 -0.52 -0.5189 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E01 compound treatment 0.28 0.0383 2.06 2.0605 1.0 1130564 Enamine_000089 CCOC(=O)c1c(NC(=O)C)scc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E02 compound treatment 0.247 0.00534 0.29 0.2872 1.0 2060550 Enamine_000090 COCc1cnc(C)nc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E03 compound treatment 0.241 -6.56E-4 -0.04 -0.0353 -1.0 2060551 Enamine_000091 COC(=O)/N=C(\Nc1c(C)cc(C)cc1C)/C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E04 compound treatment 0.262 0.0203 1.09 1.0932 1.0 2060552 Enamine_000092 COc1ccc(cc1)/C(=N/C#N)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E05 compound treatment 0.245 0.00334 0.18 0.1797 1.0 2060553 Enamine_000093 CS(=O)(=O)C1(CCCCC1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E06 compound treatment 0.295 0.0533 2.87 2.8666 1.0 1588783 Enamine_000094 Cc1ccc(NC(=O)c2cccnc2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E07 compound treatment 0.365 0.123 6.63 6.6282 1.0 2060554 Enamine_000095 OCC[n+]1c(Nc2ccccc2)scc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E08 compound treatment 0.563 0.321 17.27 17.2683 1.0 2060555 Enamine_000096 Ic1cccc(c1)c2nnc(o2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E09 compound treatment 0.503 0.261 14.04 14.0441 1.0 1570270 Enamine_000097 Cc1csc(n1)c2cc3c(ccc4ccccc43)oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E10 compound treatment 0.252 0.0103 0.56 0.5559 1.0 1682255 Enamine_000098 COc1ccc(cc1)C2C=C(C)Nc3nc4ccccc4n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E11 compound treatment 0.313 0.0713 3.83 3.8339 1.0 1705726 Enamine_000099 Brc1cccc(c1)C(=O)Oc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E12 compound treatment 0.266 0.0243 1.31 1.3082 1.0 1706002 Enamine_000100 N=c1sc2ccccc2n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E13 compound treatment 0.254 0.0123 0.66 0.6633 1.0 2060556 Enamine_000101 FC(F)(F)C(=O)NCc1cn2ccsc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E14 compound treatment 0.538 0.296 15.92 15.9249 1.0 1253405 Enamine_000102 Clc1ccc2[nH]c(=NC(=O)c3ccc(cc3)C(=O)c4ccccc4)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E15 compound treatment 0.429 0.187 10.07 10.0675 1.0 1728382 Enamine_000103 COc1ccc2N=C(CC(=O)Nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E16 compound treatment 0.26 0.0183 0.99 0.9858 1.0 2060557 Enamine_000104 COc1ccc(cc1)N2C3=[N+](CC2(C)O)CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E17 compound treatment 0.282 0.0403 2.17 2.168 1.0 1418018 Enamine_000105 CN1CCN(CC1)C(=O)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E18 compound treatment 0.425 0.183 9.85 9.8525 1.0 1046649 Enamine_000106 O=C(CSc1nc2ccccc2[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E19 compound treatment 0.327 0.0853 4.59 4.5862 1.0 2060558 Enamine_000107 Fc1ccc(cc1)c2csc(NC3=NCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E20 compound treatment 0.287 0.0453 2.44 2.4367 1.0 1376353 Enamine_000108 Cc1ccc(Sc2c(O)c3ccccc3oc2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E21 compound treatment 0.264 0.0223 1.2 1.2007 1.0 1420490 Enamine_000109 COC(=O)C(Cc1ccccc1)NC(=O)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E22 compound treatment 0.25 0.00834 0.45 0.4484 1.0 2060559 Enamine_000110 Cc1ccccc1OC2OCCOC2Oc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E23 mock treatment 0.244 0.00234 0.13 0.1259 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 E24 mock treatment 0.247 0.00534 0.29 0.2872 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F01 compound treatment 0.265 0.0233 1.25 1.2544 1.0 2060560 Enamine_000111 CN1/C(=C\C(=O)c2ccccc2)/C(C)(C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F02 compound treatment 0.255 0.0133 0.72 0.7171 1.0 1331982 Enamine_000112 Cc1nc2cc(CC(=O)O)ccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F03 compound treatment 0.241 -6.56E-4 -0.04 -0.0353 -1.0 2060561 Enamine_000113 CC1(C)CC(=C/C(=N\c2ccc(cc2)C(=O)O)/C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F04 compound treatment 0.261 0.0193 1.04 1.0395 1.0 1497093 Enamine_000114 Cc1nc2n(ncc2c(=O)[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F05 compound treatment 0.354 0.112 6.04 6.0371 1.0 1004829 Enamine_000115 c1ccc(nc1)c2cccc(n2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F06 compound treatment 0.246 0.00434 0.23 0.2334 1.0 1206549 Enamine_000116 Clc1ccccc1C(=O)N(Cc2ccccc2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F07 compound treatment 0.236 -0.00566 -0.3 -0.304 -1.0 2060562 Enamine_000117 CCN(CC)C(=S)SC(=O)c1ccccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F08 compound treatment 0.272 0.0303 1.63 1.6306 1.0 1120930 Enamine_000118 CC(=O)Nc1c(C#N)c2nc3ccccc3nc2n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F09 compound treatment 0.258 0.0163 0.88 0.8783 1.0 1331021 Enamine_000119 CC(C)(Nc1ccccc1N)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F10 compound treatment 0.268 0.0263 1.42 1.4157 1.0 1290996 Enamine_000120 COc1ccc(O)c(c1)C2SCC(=O)N2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F11 compound treatment 0.236 -0.00566 -0.3 -0.304 -1.0 1626823 Enamine_000121 CC1CCCC(C)N1CC(O)COc2c(F)cc(Br)cc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F12 compound treatment 0.417 0.175 9.42 9.4226 1.0 1220483 Enamine_000122 CC(C)CCOc1cccc(OCC(=O)Nc2ccncc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F13 compound treatment 0.23 -0.0117 -0.63 -0.6264 -1.0 1202409 Enamine_000123 CC(C)(C)C1(NC(=O)C2=C(CC(C)(C)CC2=O)O1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F14 compound treatment 0.476 0.234 12.59 12.5931 1.0 2060563 Enamine_000124 CCn1c2ccccc2c3cc(/C=N/n4cnnc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F15 compound treatment 0.238 -0.00366 -0.2 -0.1965 -1.0 1394599 Enamine_000125 Cc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)Nc3ncccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F16 compound treatment 0.236 -0.00566 -0.3 -0.304 -1.0 2060564 Enamine_000126 FC(F)(F)c1cnc(N2Cc3ccccc3C2=N)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F17 compound treatment 0.245 0.00334 0.18 0.1797 1.0 2060565 Enamine_000127 CN1C(=C)Sc2ccc(C=C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F18 compound treatment 0.436 0.194 10.44 10.4436 1.0 2060566 Enamine_000128 NC1=C(C#N)C(c2ccccc2)c3c(O1)ccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F19 compound treatment 0.31 0.0683 3.67 3.6727 1.0 2060567 Enamine_000129 CCOc1ccc(cc1)N2Cc3ccccc3C2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F20 compound treatment 0.292 0.0503 2.71 2.7054 1.0 1157724 Enamine_000130 Nc1nc(C(=O)Nc2ccccc2)c(s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F21 compound treatment 0.254 0.0123 0.66 0.6633 1.0 1021370 Enamine_000131 Oc1ccccc1NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F22 compound treatment 0.242 3.44E-4 0.02 0.0185 1.0 1702991 Enamine_000132 OC(=O)C(O)(c1ccc(Br)cc1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F23 mock treatment 0.245 0.00334 0.18 0.1797 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 F24 mock treatment 0.238 -0.00366 -0.2 -0.1965 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G01 compound treatment 0.237 -0.00466 -0.25 -0.2502 -1.0 1720564 Enamine_000133 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G02 compound treatment 0.25 0.00834 0.45 0.4484 1.0 2060568 Enamine_000134 Cc1ccc(cc1)S(=O)(=O)NC2=NCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G03 compound treatment 0.339 0.0973 5.23 5.231 1.0 2060569 Enamine_000135 Clc1ccc(cc1)S(=O)(=O)C2(CC2)C(=O)Nc3ccc(I)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G04 compound treatment 0.245 0.00334 0.18 0.1797 1.0 2060570 Enamine_000136 Cn1ccnc1C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G05 compound treatment 0.551 0.309 16.62 16.6235 1.0 1689950 Enamine_000137 OC1(COc2ccccc2O1)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G06 compound treatment 0.282 0.0403 2.17 2.168 1.0 1008557 Enamine_000138 COc1ccc(cc1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G07 compound treatment 0.235 -0.00666 -0.36 -0.3577 -1.0 1646935 Enamine_000139 O=C1CCCCCC1CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G08 compound treatment 0.248 0.00634 0.34 0.3409 1.0 1101856 Enamine_000140 CCOc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G09 compound treatment 0.519 0.277 14.9 14.9039 1.0 2060571 Enamine_000141 O=C/1N=C(O\C1=C/C=C/c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G10 compound treatment 0.354 0.112 6.04 6.0371 1.0 1543444 Enamine_000142 Cc1ccccc1C(=O)Nc2sc3CCCc3c2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G11 compound treatment 0.248 0.00634 0.34 0.3409 1.0 1591090 Enamine_000143 CC(=O)Oc1ccc(cc1)N2C(=O)CCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G12 compound treatment 0.306 0.0643 3.46 3.4577 1.0 1723857 Enamine_000144 O=C1CCCN1c2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G13 compound treatment 0.348 0.106 5.71 5.7147 1.0 2060572 Enamine_000145 O=c1[nH]c(nc2sc3CCCCc3c12)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G14 compound treatment 0.277 0.0353 1.9 1.8993 1.0 2060573 Enamine_000146 Clc1ccc(cc1)S(=O)(=O)C2(CC2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G15 compound treatment 0.434 0.192 10.34 10.3362 1.0 1237705 Enamine_000147 Oc1ccc(cc1)c2cn3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G16 compound treatment 0.432 0.19 10.23 10.2287 1.0 1375180 Enamine_000148 O=C(Cc1cccs1)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G17 compound treatment 0.267 0.0253 1.36 1.3619 1.0 2060574 Enamine_000149 Clc1ccc(SC2C(=O)CCCC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G18 compound treatment 0.248 0.00634 0.34 0.3409 1.0 2060575 Enamine_000150 [O-][n+]1ccccc1SCC(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G19 compound treatment 0.327 0.0853 4.59 4.5862 1.0 2060576 Enamine_000151 CC(=O)Nc1cc2CCCCc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G20 compound treatment 0.289 0.0473 2.54 2.5442 1.0 1633910 Enamine_000152 Oc1c(Sc2ccc(Cl)cc2)c(=O)oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G21 compound treatment 0.265 0.0233 1.25 1.2544 1.0 2060577 Enamine_000153 Oc1ccc(/C=N/c2ccccc2c3nc4ccccc4[nH]3)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G22 compound treatment 0.351 0.109 5.88 5.8759 1.0 1234606 Enamine_000154 COc1ccc(cc1)C(=O)Nc2ccc3ncsc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G23 mock treatment 0.252 0.0103 0.56 0.5559 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 G24 mock treatment 0.242 3.44E-4 0.02 0.0185 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H01 compound treatment 0.272 0.0303 1.63 1.6306 1.0 1159232 Enamine_000155 CNc1ccccc1C(C)(C)c2cc(no2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H02 compound treatment 0.275 0.0333 1.79 1.7918 1.0 2060578 Enamine_000156 SC(=S)NC1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H03 compound treatment 0.249 0.00734 0.39 0.3946 1.0 1428645 Enamine_000157 COc1cc2CCCC(N)Cc2c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H04 compound treatment 0.248 0.00634 0.34 0.3409 1.0 2060579 Enamine_000158 CC(NC1=NCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H05 compound treatment 0.382 0.14 7.54 7.5418 1.0 1671244 Enamine_000159 CC(=O)Oc1ccc2c3CCCCc3c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H06 compound treatment 0.258 0.0163 0.88 0.8783 1.0 2060580 Enamine_000160 FC(F)(F)SCC(=O)Nc1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H07 compound treatment 0.366 0.124 6.68 6.682 1.0 2060581 Enamine_000161 COc1ccc(/N=C/c2ccc3OCCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H08 compound treatment 0.329 0.0873 4.69 4.6937 1.0 1492973 Enamine_000162 Oc1ccccc1OCC(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H09 compound treatment 0.35 0.108 5.82 5.8222 1.0 1537571 Enamine_000163 COc1ccc(cc1)c2nc3ccccc3n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H10 compound treatment 0.564 0.322 17.32 17.3221 1.0 1353008 Enamine_000164 CCOc1ccc2[nH]c(=NC(=O)c3ccccc3Cl)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H11 compound treatment 0.247 0.00534 0.29 0.2872 1.0 2060582 Enamine_000165 FC(F)(Cl)c1ccc(=O)[nH]c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H12 compound treatment 0.247 0.00534 0.29 0.2872 1.0 1262075 Enamine_000166 Cc1cc(C)c(C(=O)NCc2ccco2)c(C)c1C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H13 compound treatment 0.348 0.106 5.71 5.7147 1.0 2060583 Enamine_000167 Clc1ccccc1C(=O)Sc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H14 compound treatment 0.496 0.254 13.67 13.6679 1.0 1702375 Enamine_000168 O=C(COc1cccc2ccccc12)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H15 compound treatment 0.325 0.0833 4.48 4.4787 1.0 1437238 Enamine_000169 O=C(COc1ccccc1)NCc2cn3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H16 compound treatment 0.251 0.00934 0.5 0.5021 1.0 2060584 Enamine_000170 CCCSC1=C(C#N)C(CC(=O)N1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H17 compound treatment 0.273 0.0313 1.68 1.6843 1.0 1142796 Enamine_000171 CCN1CCN(CC1)c2cc(c3ccccc3)c4ccccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H18 compound treatment 0.243 0.00134 0.07 0.0722 1.0 2060585 Enamine_000172 Cc1ccccc1NS(=O)(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H19 compound treatment 0.255 0.0133 0.72 0.7171 1.0 1216182 Enamine_000173 O=C(N1CCCCC1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H20 compound treatment 0.241 -6.56E-4 -0.04 -0.0353 -1.0 2060586 Enamine_000174 CC(C)c1cccc(C(C)C)c1NC(=O)/C=C/c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H21 compound treatment 0.25 0.00834 0.45 0.4484 1.0 1574485 Enamine_000175 Clc1ccccc1C(=O)NC2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H22 compound treatment 0.277 0.0353 1.9 1.8993 1.0 2060587 Enamine_000176 Nc1ccc(/N=C/c2ccc3OCCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H23 mock treatment 0.243 0.00134 0.07 0.0722 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 H24 mock treatment 0.246 0.00434 0.23 0.2334 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I01 compound treatment 0.271 0.0293 1.58 1.5769 1.0 2060588 Enamine_000177 COc1ccc(cc1)c2cn3CCCc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I02 compound treatment 0.268 0.0263 1.42 1.4157 1.0 2060589 Enamine_000178 N#C/C(=C\1/CCCCCN1)/c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I03 compound treatment 0.248 0.00634 0.34 0.3409 1.0 1653816 Enamine_000179 CC1(Cc2nc3ccccc3[nH]2)OCCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I04 compound treatment 0.251 0.00934 0.5 0.5021 1.0 1336938 Enamine_000180 Ic1ccccc1NC(=O)C2(CCCC2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I05 compound treatment 0.292 0.0503 2.71 2.7054 1.0 1443715 Enamine_000181 CC1=C(Oc2ccccc2O1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I06 compound treatment 0.251 0.00934 0.5 0.5021 1.0 1294772 Enamine_000182 O=C(NS(=O)(=O)NC(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I07 compound treatment 0.244 0.00234 0.13 0.1259 1.0 2060590 Enamine_000183 C(c1ccccc1)n2cn[n+](Cc3ccccc3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I08 compound treatment 0.252 0.0103 0.56 0.5559 1.0 2060591 Enamine_000184 CN(C)c1cccc(c1)N2Cc3ccccc3C2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I09 compound treatment 0.535 0.293 15.76 15.7637 1.0 1099026 Enamine_000185 CCN(CC)c1ccc2cc(c3nc4ccccc4[nH]3)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I10 compound treatment 0.516 0.274 14.74 14.7427 1.0 1702433 Enamine_000186 COc1ccc2nc(NC(=O)c3ccccc3C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I11 compound treatment 0.259 0.0173 0.93 0.932 1.0 1220570 Enamine_000187 OCc1csc(=Nc2ccccc2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I12 compound treatment 0.293 0.0513 2.76 2.7591 1.0 1399299 Enamine_000188 CC1Cc2ccccc2N1C(=O)c3ccc(cc3)S(=O)(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I13 compound treatment 0.45 0.208 11.2 11.196 1.0 1377821 Enamine_000189 CCOc1ccc2nc(NC(=O)C(C)C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I14 compound treatment 0.24 -0.00166 -0.09 -0.089 -1.0 2060592 Enamine_000190 OCCOc1ccccc1OCCBr 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I15 compound treatment 0.262 0.0203 1.09 1.0932 1.0 2060593 Enamine_000191 CC1(C)Cc2snc(C(=O)N)c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I16 compound treatment 0.248 0.00634 0.34 0.3409 1.0 2060594 Enamine_000192 CSc1nc(nc2CCCCc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I17 compound treatment 0.283 0.0413 2.22 2.2217 1.0 1740367 Enamine_000193 Cc1cc(C)c(OCC(O)CNC2CC(C)(C)NC(C)(C)C2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I18 compound treatment 0.263 0.0213 1.15 1.147 1.0 1139403 Enamine_000194 CCN1CCN(CC1)c2cc(C)c3ccc(OC)cc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I19 compound treatment 0.32 0.0783 4.21 4.21 1.0 1915045 Enamine_000195 CC(=O)Nc1sc2CCCCc2c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I20 compound treatment 0.316 0.0743 4.0 3.9951 1.0 2060595 Enamine_000196 N/1/C(=N\c2ccccc2)/c3ccccc3\C1=N\c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I21 compound treatment 0.304 0.0623 3.35 3.3502 1.0 1298770 Enamine_000197 Cc1ccc(NC(=O)COc2ccccc2O)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I22 compound treatment 0.287 0.0453 2.44 2.4367 1.0 1372987 Enamine_000198 Clc1ccc2N(CCC#N)C(=O)c3cccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I23 mock treatment 0.248 0.00634 0.34 0.3409 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 I24 mock treatment 0.258 0.0163 0.88 0.8783 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J01 compound treatment 0.366 0.124 6.68 6.682 1.0 2060596 Enamine_000199 CC(=O)N1CCN(CC1)C(=O)COc2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J02 compound treatment 0.344 0.102 5.5 5.4997 1.0 1291969 Enamine_000200 CC(=O)Oc1ccc2c3CCCc3c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J03 compound treatment 0.297 0.0553 2.97 2.9741 1.0 1194922 Enamine_000201 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J04 compound treatment 0.246 0.00434 0.23 0.2334 1.0 2060597 Enamine_000202 CC(NC1=NCCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J05 compound treatment 0.247 0.00534 0.29 0.2872 1.0 1527481 Enamine_000203 CC1(C)CC(=C(CC2=C(O)CC(C)(C)CC2=O)C(=O)C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J06 compound treatment 0.257 0.0153 0.82 0.8245 1.0 1302644 Enamine_000204 CC1CN(CC(C)O1)C(=O)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J07 compound treatment 0.245 0.00334 0.18 0.1797 1.0 1201090 Enamine_000205 CCn1cnc(C(=O)NC)c1C(=O)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J08 compound treatment 0.239 -0.00266 -0.14 -0.1427 -1.0 2060598 Enamine_000206 OC(=O)/C=C/C(=O)N1CCN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J09 compound treatment 0.412 0.17 9.15 9.1539 1.0 2060599 Enamine_000207 O1C=C(Oc2ccccc12)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J10 compound treatment 0.267 0.0253 1.36 1.3619 1.0 2060600 Enamine_000208 COC(=O)/N=C(/Nc1ccc(OC)cc1)\C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J11 compound treatment 0.407 0.165 8.89 8.8852 1.0 1129484 Enamine_000209 Brc1ccc2nc(cn2c1)C(C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J12 compound treatment 0.298 0.0563 3.03 3.0278 1.0 1584962 Enamine_000210 CC(C)C(=O)N(C1CC(C)Nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J13 compound treatment 0.245 0.00334 0.18 0.1797 1.0 1285385 Enamine_000211 CC(=O)NC(CSCc1ccccc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J14 compound treatment 0.244 0.00234 0.13 0.1259 1.0 2060601 Enamine_000212 CC1(C)OC(=O)C1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J15 compound treatment 0.288 0.0463 2.49 2.4904 1.0 2060602 Enamine_000213 Cc1nc2cc(CCl)ccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J16 compound treatment 0.249 0.00734 0.39 0.3946 1.0 2060603 Enamine_000214 CS(=O)(=O)n1cc(ccc1=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J17 compound treatment 0.485 0.243 13.08 13.0768 1.0 2060604 Enamine_000215 FC(F)(F)Sc1ccc(NC(=O)c2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J18 compound treatment 0.493 0.251 13.51 13.5067 1.0 2060605 Enamine_000216 Cc1cc(N)n(CCC#N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J19 compound treatment 0.335 0.0933 5.02 5.0161 1.0 1575843 Enamine_000217 Clc1cc(Cl)cc(c1)C(=O)NCc2cn3ccsc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J20 compound treatment 0.45 0.208 11.2 11.196 1.0 2060606 Enamine_000218 FC(F)(F)c1cccc(NC(=O)c2ccccn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J21 compound treatment 0.226 -0.0157 -0.84 -0.8413 -1.0 1190671 Enamine_000219 CNc1ccccc1C(C)(C)c2ccn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J22 compound treatment 0.274 0.0323 1.74 1.7381 1.0 2060607 Enamine_000220 ClCC1Cc2cc(I)c(Cl)cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J23 mock treatment 0.24 -0.00166 -0.09 -0.089 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 J24 mock treatment 0.242 3.44E-4 0.02 0.0185 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K01 compound treatment 0.259 0.0173 0.93 0.932 1.0 2060608 Enamine_000221 CCn1c(C)nc2cc(OC)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K02 compound treatment 0.515 0.273 14.69 14.6889 1.0 2060609 Enamine_000222 Brc1ccc(cc1)n2cnc(c2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K03 compound treatment 0.274 0.0323 1.74 1.7381 1.0 1159773 Enamine_000223 COc1ccc2c(cc(O)nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K04 compound treatment 0.276 0.0343 1.85 1.8456 1.0 1691179 Enamine_000224 Oc1nnc(Cc2ccncc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K05 compound treatment 0.453 0.211 11.36 11.3572 1.0 2060610 Enamine_000225 O=C(OCC1COc2ccccc2O1)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K06 compound treatment 0.338 0.0963 5.18 5.1773 1.0 1398562 Enamine_000226 O=C(CNc1ccccc1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K07 compound treatment 0.467 0.225 12.11 12.1095 1.0 2060611 Enamine_000227 CN(C)c1ccc(/C=C/C=N/n2cnnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K08 compound treatment 0.249 0.00734 0.39 0.3946 1.0 1267740 Enamine_000228 CCOC(=O)N=S(=O)(N)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K09 compound treatment 0.288 0.0463 2.49 2.4904 1.0 2060612 Enamine_000229 Cc1ccc(/N=C\c2ccc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K10 compound treatment 0.393 0.151 8.13 8.1329 1.0 1265992 Enamine_000230 COc1ccc(cc1OC)c2cn3Cc4ccccc4-c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K11 compound treatment 0.252 0.0103 0.56 0.5559 1.0 2060613 Enamine_000231 CCN(CC)CCOc1ccc(cc1)/C(=N\O)/C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K12 compound treatment 0.546 0.304 16.35 16.3548 1.0 1478202 Enamine_000232 CSc1nc2ccc(NC(=O)c3ccc(F)c(F)c3)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K13 compound treatment 0.25 0.00834 0.45 0.4484 1.0 2060614 Enamine_000233 CC1(C)CC(=C/C(=N/c2ccc(F)cc2)/C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K14 compound treatment 0.259 0.0173 0.93 0.932 1.0 2060615 Enamine_000234 CC1(CCCC1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K15 compound treatment 0.49 0.248 13.35 13.3455 1.0 2060616 Enamine_000235 O=C(Sc1nc2ccccc2o1)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K16 compound treatment 0.345 0.103 5.55 5.5535 1.0 2060617 Enamine_000236 Cc1nc2ccccc2nc1SCC(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K17 compound treatment 0.564 0.322 17.32 17.3221 1.0 1675382 Enamine_000237 Cc1ccc(cc1)C(=O)COc2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K18 compound treatment 0.264 0.0223 1.2 1.2007 1.0 1913506 Enamine_000238 CCc1n[n+](CC(=O)c2ccccc2)c(N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K19 compound treatment 0.298 0.0563 3.03 3.0278 1.0 2060618 Enamine_000239 Fc1cccc(c1)C(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K20 compound treatment 0.252 0.0103 0.56 0.5559 1.0 2060619 Enamine_000240 CC1(C)CC(=O)C(=Cc2ccc3OCCOc3c2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K21 compound treatment 0.338 0.0963 5.18 5.1773 1.0 1738171 Enamine_000241 CN1CCN(CC1)C(=O)COc2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K22 compound treatment 0.316 0.0743 4.0 3.9951 1.0 2060620 Enamine_000242 COc1ccc(/C=C/C(=O)Nc2ccc(C)cc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K23 mock treatment 0.247 0.00534 0.29 0.2872 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 K24 mock treatment 0.246 0.00434 0.23 0.2334 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L01 compound treatment 0.227 -0.0147 -0.79 -0.7876 -1.0 1445657 Enamine_000243 NC(=O)CS(=O)(=O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L02 compound treatment 0.276 0.0343 1.85 1.8456 1.0 1599948 Enamine_000244 Cc1cccc(OCC(=O)NCc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L03 compound treatment 0.411 0.169 9.1 9.1002 1.0 1523758 Enamine_000245 OC1(COc2ccccc2O1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L04 compound treatment 0.248 0.00634 0.34 0.3409 1.0 2060621 Enamine_000246 OC(=O)/C=C/C(=O)N1CCC(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L05 compound treatment 0.273 0.0313 1.68 1.6843 1.0 1447952 Enamine_000247 CC(C)c1ccc(OCC(O)CN2CC(C)OC(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L06 compound treatment 0.295 0.0533 2.87 2.8666 1.0 2060622 Enamine_000248 O=C(c1ccc2ccccc2n1)n3nc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L07 compound treatment 0.289 0.0473 2.54 2.5442 1.0 1546288 Enamine_000249 Fc1ccc(cc1)C(=O)Nc2ncnc3sc4CCCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L08 compound treatment 0.239 -0.00266 -0.14 -0.1427 -1.0 2060623 Enamine_000250 CC(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L09 compound treatment 0.252 0.0103 0.56 0.5559 1.0 1520257 Enamine_000251 CC(CC(=O)O)C(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L10 compound treatment 0.281 0.0393 2.11 2.1143 1.0 1564833 Enamine_000252 O=C(NC1CCS(=O)(=O)C1)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L11 compound treatment 0.348 0.106 5.71 5.7147 1.0 2060624 Enamine_000253 Fc1ccc(cc1)c2nn(cc2/C=C/C(=O)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L12 compound treatment 0.28 0.0383 2.06 2.0605 1.0 1439805 Enamine_000254 CCc1nc2n(ncc2c3nncn13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L13 compound treatment 0.275 0.0333 1.79 1.7918 1.0 1330114 Enamine_000255 CN(C(=O)c1ccc(cc1)S(=O)(=O)N2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L14 compound treatment 0.247 0.00534 0.29 0.2872 1.0 2060625 Enamine_000256 CC1C=Cc2ccccc2N1C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L15 compound treatment 0.514 0.272 14.64 14.6352 1.0 2060626 Enamine_000257 COc1ccc(/C=C/C(=O)Sc2cccc3cccnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L16 compound treatment 0.461 0.219 11.79 11.7871 1.0 1623925 Enamine_000258 O=C(Nc1ccncc1)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L17 compound treatment 0.479 0.237 12.75 12.7544 1.0 1175508 Enamine_000259 Cc1ccc(NC(=O)c2cc3ccccc3o2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L18 compound treatment 0.235 -0.00666 -0.36 -0.3577 -1.0 2060627 Enamine_000260 COC(=O)C1(CC=CC1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L19 compound treatment 0.29 0.0483 2.6 2.5979 1.0 2060628 Enamine_000261 Cc1ccc(/N=C/c2ccc3OCCOc3c2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L20 compound treatment 0.225 -0.0167 -0.9 -0.8951 -1.0 2060629 Enamine_000262 Cc1c(cc2ccccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L21 compound treatment 0.234 -0.00766 -0.41 -0.4114 -1.0 2060630 Enamine_000263 NC(=O)CC1(OCCO1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L22 compound treatment 0.258 0.0163 0.88 0.8783 1.0 1607228 Enamine_000264 C=CCNc1nn(c2nc3ccccc3s2)c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L23 mock treatment 0.244 0.00234 0.13 0.1259 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 L24 mock treatment 0.229 -0.0127 -0.68 -0.6801 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M01 compound treatment 0.241 -6.56E-4 -0.04 -0.0353 -1.0 2060631 Enamine_000265 Cc1n(C)c2ccccc2[n+]1c3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M02 compound treatment 0.244 0.00234 0.13 0.1259 1.0 2060632 Enamine_000266 Cc1ccc(cc1)S(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M03 compound treatment 0.234 -0.00766 -0.41 -0.4114 -1.0 1427443 Enamine_000267 CC(C)N(C(=O)C1(CC2CC3CC(C2)C1)C3)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M04 compound treatment 0.258 0.0163 0.88 0.8783 1.0 1048264 Enamine_000268 CSc1sc2ccccc2[n+]1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M05 compound treatment 0.472 0.23 12.38 12.3782 1.0 1153647 Enamine_000269 Cc1ncc(s1)c2cc3c(ccc4ccccc43)oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M06 compound treatment 0.26 0.0183 0.99 0.9858 1.0 1382151 Enamine_000270 Cc1ccc(cc1)S(=O)(=O)N2CCCCC2C(=O)N3CCCC4CCCCC43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M07 compound treatment 0.344 0.102 5.5 5.4997 1.0 2060633 Enamine_000271 Cc1csc(NC2=NCCCCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M08 compound treatment 0.245 0.00334 0.18 0.1797 1.0 1953832 Enamine_000272 NC(=N)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M09 compound treatment 0.542 0.3 16.14 16.1398 1.0 2060634 Enamine_000273 CN(C)c1ccc(/N=C/c2c(O)ccc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M10 compound treatment 0.318 0.0763 4.1 4.1026 1.0 2060635 Enamine_000274 C1CCn2c(cnc2C1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M11 compound treatment 0.471 0.229 12.32 12.3245 1.0 2060636 Enamine_000275 COc1ccc2/C(=C/Nc3ccccc3)/C(=O)N(C)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M12 compound treatment 0.265 0.0233 1.25 1.2544 1.0 1983631 Enamine_000276 CN(C)S(=O)(=O)Nc1cccc(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M13 compound treatment 0.312 0.0703 3.78 3.7801 1.0 2060637 Enamine_000277 Cc1ccc(cc1)c2csc(Nc3ccccc3)[n+]2NC(=O)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M14 compound treatment 0.264 0.0223 1.2 1.2007 1.0 2060638 Enamine_000278 Cc1ccc(cc1)S(=O)(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M15 compound treatment 0.261 0.0193 1.04 1.0395 1.0 2060639 Enamine_000279 CC[n+]1c(C)sc2ccc(CC(=O)O)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M16 compound treatment 0.378 0.136 7.33 7.3268 1.0 2060640 Enamine_000280 O/N=C(\Cc1nc2ccccc2s1)/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M17 compound treatment 0.263 0.0213 1.15 1.147 1.0 1469630 Enamine_000281 CC(=O)NC(C1CCCCC1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M18 compound treatment 0.487 0.245 13.18 13.1843 1.0 2060641 Enamine_000282 COc1ccc2cc(c3nc4ccccc4[nH]3)c(N)[o+]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M19 compound treatment 0.376 0.134 7.22 7.2194 1.0 1282910 Enamine_000283 Cc1cccc(NC(=O)CC(=O)c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M20 compound treatment 0.303 0.0613 3.3 3.2965 1.0 1142044 Enamine_000284 OCCN1C(SCC1=O)c2cn(nc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M21 compound treatment 0.337 0.0953 5.12 5.1236 1.0 1253879 Enamine_000285 COc1ccc2CC(=O)N(Cc3ccccc3)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M22 compound treatment 0.254 0.0123 0.66 0.6633 1.0 1164194 Enamine_000286 COc1ccc(NC(=O)c2ccc(F)c(F)c2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M23 mock treatment 0.243 0.00134 0.07 0.0722 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 M24 mock treatment 0.246 0.00434 0.23 0.2334 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N01 compound treatment 0.242 3.44E-4 0.02 0.0185 1.0 1321141 Enamine_000287 CC1N(C)c2ccc(NC(=O)C)cc2C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N02 compound treatment 0.299 0.0573 3.08 3.0815 1.0 1679896 Enamine_000288 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N03 compound treatment 0.248 0.00634 0.34 0.3409 1.0 1920250 Enamine_000289 CN(/C=C/C=[N+](\C)/c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N04 compound treatment 0.267 0.0253 1.36 1.3619 1.0 2060642 Enamine_000290 Cc1cc(NC2=CC(=O)CCC2)ccc1I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N05 compound treatment 0.33 0.0883 4.75 4.7474 1.0 1057118 Enamine_000291 FC(F)(F)C(=O)Nc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N06 compound treatment 0.512 0.27 14.53 14.5277 1.0 1714957 Enamine_000292 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)c4ccncc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N07 compound treatment 0.449 0.207 11.14 11.1422 1.0 1519751 Enamine_000293 COc1cccc2sc(=NC(=O)c3ccccc3Cl)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N08 compound treatment 0.319 0.0773 4.16 4.1563 1.0 1251008 Enamine_000294 Brc1c(CSC2CCS(=O)(=O)C2)nc3ccccn13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N09 compound treatment 0.243 0.00134 0.07 0.0722 1.0 1525743 Enamine_000295 NC(=O)CC1CS(=O)(=O)C=C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N10 compound treatment 0.243 0.00134 0.07 0.0722 1.0 1594703 Enamine_000296 Fc1ccc(cc1)C(=O)N(C(=O)c2ccc(F)cc2)c3ncccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N11 compound treatment 0.256 0.0143 0.77 0.7708 1.0 1625316 Enamine_000297 OC1Oc2ccccc2OC1C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N12 compound treatment 0.381 0.139 7.49 7.488 1.0 1497186 Enamine_000298 CN(Cc1ccccc1)C(=O)COc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N13 compound treatment 0.249 0.00734 0.39 0.3946 1.0 2060643 Enamine_000299 Cc1ccc(OC(=O)NC2(OCCO2)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N14 compound treatment 0.238 -0.00366 -0.2 -0.1965 -1.0 2060644 Enamine_000300 CC[N+](=c1[nH]c2ccccc2s1)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N15 compound treatment 0.245 0.00334 0.18 0.1797 1.0 2060645 Enamine_000301 COc1ccccc1[n+]2c(C)cc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N16 compound treatment 0.24 -0.00166 -0.09 -0.089 -1.0 2060646 Enamine_000302 C=C1C(C1C(=O)NCc2ccco2)C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N17 compound treatment 0.278 0.0363 1.95 1.953 1.0 2060647 Enamine_000303 ClCCCC(=O)Nc1ccccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N18 compound treatment 0.255 0.0133 0.72 0.7171 1.0 1147613 Enamine_000304 C=C1C(C1C(=O)Nc2ccccc2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N19 compound treatment 0.246 0.00434 0.23 0.2334 1.0 2060648 Enamine_000305 Brc1ccc(/N=C/c2ccc3OCCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N20 compound treatment 0.277 0.0353 1.9 1.8993 1.0 2060649 Enamine_000306 Brc1ccc(cc1)C(=O)OCC2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N21 compound treatment 0.237 -0.00466 -0.25 -0.2502 -1.0 2060650 Enamine_000307 Cc1sc2cc(ccc2[n+]1c3ccccc3)[n+]4ccc(O)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N22 compound treatment 0.234 -0.00766 -0.41 -0.4114 -1.0 2060651 Enamine_000308 COC(=O)c1c(OC)n(nc1c2ccccc2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N23 mock treatment 0.236 -0.00566 -0.3 -0.304 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 N24 mock treatment 0.233 -0.00866 -0.47 -0.4652 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O01 compound treatment 0.247 0.00534 0.29 0.2872 1.0 1536133 Enamine_000309 CC(=O)Nc1sc2CCCCc2c1CN3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O02 compound treatment 0.258 0.0163 0.88 0.8783 1.0 2060652 Enamine_000310 C/C(=C(/N)\c1ccccc1)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O03 compound treatment 0.452 0.21 11.3 11.3034 1.0 1030656 Enamine_000311 CCSc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O04 compound treatment 0.255 0.0133 0.72 0.7171 1.0 1142785 Enamine_000312 NC(=O)CCS(=O)(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O05 compound treatment 0.274 0.0323 1.74 1.7381 1.0 2060653 Enamine_000313 Oc1ccccc1/C=N/c2nnc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O06 compound treatment 0.246 0.00434 0.23 0.2334 1.0 2060654 Enamine_000314 Oc1ccccc1/C=N/[n+]2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O07 compound treatment 0.408 0.166 8.94 8.939 1.0 2060655 Enamine_000315 O=C/1OC(=N\C1=C/2\CCc3ccccc3N2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O08 compound treatment 0.266 0.0243 1.31 1.3082 1.0 1574848 Enamine_000316 COc1cccc(c1)C(=O)Oc2ccc3C(=CC(C)(C)Nc3c2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O09 compound treatment 0.554 0.312 16.78 16.7847 1.0 1155435 Enamine_000317 COc1ccc(cc1)N2Cc3ccc(OC)c(OC)c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O10 compound treatment 0.292 0.0503 2.71 2.7054 1.0 1702340 Enamine_000318 C(C#Cc1ccccc1)N2CCN(CC2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O11 compound treatment 0.311 0.0693 3.73 3.7264 1.0 2060656 Enamine_000319 Fc1ccc(cc1)C(=O)N=c2[nH]ccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O12 compound treatment 0.481 0.239 12.86 12.8618 1.0 1514080 Enamine_000320 CCc1ccc(cc1)c2csc(=NC(=O)c3cccs3)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O13 compound treatment 0.308 0.0663 3.57 3.5652 1.0 1250613 Enamine_000321 O=C(Nc1ccc(NC(=O)c2cccnc2)cc1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O14 compound treatment 0.355 0.113 6.09 6.0909 1.0 1917012 Enamine_000322 NNc1nc(cc(n1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O15 compound treatment 0.24 -0.00166 -0.09 -0.089 -1.0 1448512 Enamine_000323 C[N+]1(CCOS(=O)C2(CC3CC4CC(C3)C2)C4)CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O16 compound treatment 0.366 0.124 6.68 6.682 1.0 1295901 Enamine_000324 CCN(CC)c1ncnc2sc3CCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O17 compound treatment 0.285 0.0433 2.33 2.3292 1.0 1517789 Enamine_000325 CC(C)C1CCC(C)CC1OCC(O)CN2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O18 compound treatment 0.247 0.00534 0.29 0.2872 1.0 2060657 Enamine_000326 C(=N/[n+]1ccccc1)\c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O19 compound treatment 0.315 0.0733 3.94 3.9413 1.0 1213677 Enamine_000327 Cc1cccc(NCc2cn3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O20 compound treatment 0.249 0.00734 0.39 0.3946 1.0 2060658 Enamine_000328 CC(C)c1nc(C)cc(O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O21 compound treatment 0.261 0.0193 1.04 1.0395 1.0 1120123 Enamine_000329 NCCSc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O22 compound treatment 0.243 0.00134 0.07 0.0722 1.0 1488496 Enamine_000330 COC(=O)CC1(CC2CC3C1)CC(C2)(C3)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O23 mock treatment 0.242 3.44E-4 0.02 0.0185 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 O24 mock treatment 0.244 0.00234 0.13 0.1259 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P01 compound treatment 0.266 0.0243 1.31 1.3082 1.0 2060659 Enamine_000331 Cc1ccc(cc1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P02 compound treatment 0.233 -0.00866 -0.47 -0.4652 -1.0 1684080 Enamine_000332 CC(C)C(NS(=O)(=O)c1ccc(C)cc1)C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P03 compound treatment 0.233 -0.00866 -0.47 -0.4652 -1.0 1083 Enamine_000333 C(C1=NCCN1)c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P04 compound treatment 0.258 0.0163 0.88 0.8783 1.0 2060660 Enamine_000334 Ic1ccc(NC2=CC(=O)CCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P05 compound treatment 0.256 0.0143 0.77 0.7708 1.0 1250228 Enamine_000335 COc1cccc(c1)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P06 compound treatment 0.254 0.0123 0.66 0.6633 1.0 1703691 Enamine_000336 COc1ccccc1NC(=O)COc2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P07 compound treatment 0.237 -0.00466 -0.25 -0.2502 -1.0 1514594 Enamine_000337 O=S1(=O)CC(C=C1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P08 compound treatment 0.297 0.0553 2.97 2.9741 1.0 2060661 Enamine_000338 COc1ccc(cc1)c2nc(N)s[n+]2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P09 compound treatment 0.232 -0.00966 -0.52 -0.5189 -1.0 2060662 Enamine_000339 CC1Oc2ccccc2OC1(O)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P10 compound treatment 0.42 0.178 9.58 9.5838 1.0 1437433 Enamine_000340 COc1cccc(OCC(=O)Nc2ccncc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P11 compound treatment 0.251 0.00934 0.5 0.5021 1.0 1328931 Enamine_000341 O=C1NC(C=C(C1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P12 compound treatment 0.264 0.0223 1.2 1.2007 1.0 1352119 Enamine_000342 O=C(CC1COc2ccccc2O1)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P13 compound treatment 0.488 0.246 13.24 13.238 1.0 2060663 Enamine_000343 CO/C(=C\c1cccc(O)c1)/C(=O)Nc2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P14 compound treatment 0.234 -0.00766 -0.41 -0.4114 -1.0 1151013 Enamine_000344 CCN1CCN(CC1)C(=O)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P15 compound treatment 0.285 0.0433 2.33 2.3292 1.0 1588395 Enamine_000345 CC(C)c1c(C)c2ccc(O)cc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P16 compound treatment 0.278 0.0363 1.95 1.953 1.0 1193685 Enamine_000346 CC(C)(C)c1csc(NC(=O)c2ccncc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P17 compound treatment 0.364 0.122 6.57 6.5745 1.0 2060664 Enamine_000347 COc1ccc(/N=C/c2ccc3ncccc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P18 compound treatment 0.504 0.262 14.1 14.0978 1.0 2060665 Enamine_000348 Oc1ccc2ccccc2c1/C=N/Cc3cn4ccsc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P19 compound treatment 0.228 -0.0137 -0.73 -0.7339 -1.0 2060666 Enamine_000349 O=S1(=O)CCC(C1)C(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P20 compound treatment 0.413 0.171 9.21 9.2077 1.0 2060667 Enamine_000350 Cc1ccc(cn1)C(O)C/N=C/c2c(O)ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P21 compound treatment 0.24 -0.00166 -0.09 -0.089 -1.0 1265486 Enamine_000351 Cc1nc2cc(ccc2n1c3ccccc3)n4ccc(=O)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P22 compound treatment 0.296 0.0543 2.92 2.9203 1.0 2060668 Enamine_000352 COc1ccc(cc1)C2(NC(=O)C3=C(CC(C)(C)CC3=O)O2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P23 mock treatment 0.233 -0.00866 -0.47 -0.4652 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1394 P24 mock treatment 0.241 -6.56E-4 -0.04 -0.0353 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A01 compound treatment 0.274 0.0243 1.31 1.3082 1.0 1467442 Enamine_000353 O=C1CCCC(=C1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A02 compound treatment 0.231 -0.0187 -1.0 -1.0025 -1.0 1666591 Enamine_000354 CC1(CC2(C)CC3(C)C1)CC(C2)(C3)C(=O)NCCc4ccc(cc4)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A03 compound treatment 0.27 0.0203 1.09 1.0932 1.0 2060669 Enamine_000355 ClC(=C1N=C(NC1=O)c2ccccc2)Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A04 compound treatment 0.234 -0.0157 -0.84 -0.8413 -1.0 1918096 Enamine_000356 COc1ccc(OC)c(c1)c2n(C)c3ccccc3[n+]2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A05 compound treatment 0.232 -0.0177 -0.95 -0.9488 -1.0 2060670 Enamine_000357 CCn1c(C)nc2cc(O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A06 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1412972 Enamine_000358 O=C1NC(Oc2ccccc12)c3cccc(Oc4ccccc4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A07 compound treatment 0.303 0.0533 2.87 2.8666 1.0 2060671 Enamine_000359 Fc1ccc(/C=C\2/SC(=N)NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A08 compound treatment 0.253 0.00334 0.18 0.1797 1.0 1475449 Enamine_000360 CCc1nnc2c3ccccc3nc(c4ccncc4)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A09 compound treatment 0.22 -0.0297 -1.59 -1.5937 -1.0 2060672 Enamine_000361 CCOC(=O)c1c(NC(=O)C(F)(F)F)scc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A10 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 1727528 Enamine_000362 CN(C)CCOC(=O)c1ccccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A11 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1555783 Enamine_000363 CC(C)(C)C1CCC(CC1)OCC(O)CN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A12 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 2060673 Enamine_000364 COC(=C(C#N)C#N)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A13 compound treatment 0.233 -0.0167 -0.9 -0.8951 -1.0 1257779 Enamine_000365 CC(NC(=O)c1cccs1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A14 compound treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 1204468 Enamine_000366 COc1cc(C(=O)Nc2ccc(O)cc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A15 compound treatment 0.251 0.00134 0.07 0.0722 1.0 2060674 Enamine_000367 C(=N/c1cnc2ccc3ccccc3c2c1)\c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A16 compound treatment 0.321 0.0713 3.83 3.8339 1.0 2060675 Enamine_000368 CSC(=S)Nc1ccc(cc1)c2nc3ccc(C)cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A17 compound treatment 0.235 -0.0147 -0.79 -0.7876 -1.0 1662076 Enamine_000369 COc1cccc(NC(=O)C2C(C(=O)Nc3cccc(OC)c3)C2=C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A18 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 1313471 Enamine_000370 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A19 compound treatment 0.275 0.0253 1.36 1.3619 1.0 2060676 Enamine_000371 Cn1cnnc1SCc2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A20 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1508789 Enamine_000372 Cc1c(oc2ccccc12)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A21 compound treatment 0.23 -0.0197 -1.06 -1.0563 -1.0 1582552 Enamine_000373 COc1cc(OC)cc(c1)C(=O)c2c(C)c(C#N)c3ccccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A22 compound treatment 0.326 0.0763 4.1 4.1026 1.0 2060677 Enamine_000374 Cc1cc2nc(SCC(=O)C(C)(C)C)[nH]c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A23 mock treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 A24 mock treatment 0.244 -0.00566 -0.3 -0.304 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B01 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 2060678 Enamine_000375 Cn1cc(C=C2C(=O)CC(C)(C)CC2=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B02 compound treatment 0.298 0.0483 2.6 2.5979 1.0 1650123 Enamine_000376 CCc1cc(C(=O)O)c(NC(=O)c2ccc(Br)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B03 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 1126282 Enamine_000377 CN(C1CCN(C)CC1)C(=O)c2cc(Cl)cc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B04 compound treatment 0.278 0.0283 1.52 1.5231 1.0 1635795 Enamine_000378 Nc1nc2ccccc2n1CCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B05 compound treatment 0.298 0.0483 2.6 2.5979 1.0 1440586 Enamine_000379 CCCCn1c(nc2ccccc12)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B06 compound treatment 0.262 0.0123 0.66 0.6633 1.0 1591701 Enamine_000380 CS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B07 compound treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 1595282 Enamine_000381 CC(=O)Oc1cc2oc(=O)c3CCCc3c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B08 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1319084 Enamine_000382 CC[N+]1(CC(O)COC2CC(C)CC(C)(C)C2)CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B09 compound treatment 0.304 0.0543 2.92 2.9203 1.0 2060679 Enamine_000383 COc1ccc(/N=C\2/N=C(N)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B10 compound treatment 0.239 -0.0107 -0.57 -0.5726 -1.0 1511938 Enamine_000384 CC(C)(C)C(=O)NCC(N1CCOCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B11 compound treatment 0.244 -0.00566 -0.3 -0.304 -1.0 2060680 Enamine_000385 Cc1ccc(cc1Cl)N2Cc3ccccc3C2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B12 compound treatment 0.235 -0.0147 -0.79 -0.7876 -1.0 1607540 Enamine_000386 COc1cccc(c1)C(=O)N(c2ccccn2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B13 compound treatment 0.266 0.0163 0.88 0.8783 1.0 2060681 Enamine_000387 OC(=O)c1ccccc1C(=O)Cc2ccc(I)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B14 compound treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 1379372 Enamine_000388 CN(C)CC1CCCCC1OC(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B15 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 1216574 Enamine_000389 Cc1oc2cc(O)ccc2c(=O)c1c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B16 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1251205 Enamine_000390 O=C(Nc1ccccc1)C2CC3CCCC(C2)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B17 compound treatment 0.522 0.272 14.64 14.6352 1.0 2060682 Enamine_000391 COc1ccc(/C=C/C(=O)Nc2ccn(n2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B18 compound treatment 0.339 0.0893 4.8 4.8011 1.0 2060683 Enamine_000392 CNc1nc(c2ccccc2)[n+](s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B19 compound treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 1578080 Enamine_000393 CC1CC(CC(C)(C)C1)OCC(O)C[N+]2(C)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B20 compound treatment 0.478 0.228 12.27 12.2707 1.0 1920525 Enamine_000394 Oc1ccccc1OCc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B21 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 2060684 Enamine_000395 Nc1scc[n+]1Cc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B22 compound treatment 0.268 0.0183 0.99 0.9858 1.0 1206216 Enamine_000396 OC(=O)c1cccc(Oc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B23 mock treatment 0.244 -0.00566 -0.3 -0.304 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 B24 mock treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C01 compound treatment 0.238 -0.0117 -0.63 -0.6264 -1.0 2060685 Enamine_000397 CC1(C)CCCC(C)(C)N1Sc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C02 compound treatment 0.298 0.0483 2.6 2.5979 1.0 1446621 Enamine_000398 Clc1ccc2[nH]c(=NC(=O)c3ccc(Br)s3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C03 compound treatment 0.241 -0.00866 -0.47 -0.4652 -1.0 1255628 Enamine_000399 CC(=O)NC1=C(C(=O)c2ccccc2C1=O)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C04 compound treatment 0.241 -0.00866 -0.47 -0.4652 -1.0 2060686 Enamine_000400 Cn1c(c2ccc(Cl)cc2)[n+](C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C05 compound treatment 0.26 0.0103 0.56 0.5559 1.0 2060687 Enamine_000401 CSC(=S)n1c(C)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C06 compound treatment 0.271 0.0213 1.15 1.147 1.0 1668675 Enamine_000402 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C07 compound treatment 0.25 3.44E-4 0.02 0.0185 1.0 2060688 Enamine_000403 Nc1nc(Cl)c(c(Cl)n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C08 compound treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 2060689 Enamine_000404 BrC1(CC2CC3C1)CC(CC(=O)NCC4CCCO4)(C2)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C09 compound treatment 0.463 0.213 11.46 11.4646 1.0 2060690 Enamine_000405 COc1ccc(cc1)c2cc(=NO)c3cc(F)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C10 compound treatment 0.244 -0.00566 -0.3 -0.304 -1.0 2060691 Enamine_000406 OCN1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C11 compound treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 1488292 Enamine_000407 CC(C)(C)C1CCC(CC1)OCC(O)CN2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C12 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1033593 Enamine_000408 OC(=O)c1cccc(Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C13 compound treatment 0.252 0.00234 0.13 0.1259 1.0 1344353 Enamine_000409 CC(C)c1cccc(C(C)C)c1NC(=O)c2ccc3ncccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C14 compound treatment 0.446 0.196 10.55 10.5511 1.0 2060692 Enamine_000410 CN(C)c1ccc(/C=C\2/Sc3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C15 compound treatment 0.272 0.0223 1.2 1.2007 1.0 2060693 Enamine_000411 Cc1cc(C=C2C(=O)CCCC2=O)c(C)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C16 compound treatment 0.314 0.0643 3.46 3.4577 1.0 1389450 Enamine_000412 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(O)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C17 compound treatment 0.257 0.00734 0.39 0.3946 1.0 2060694 Enamine_000413 COC(=O)NC(=C(Cl)Cl)c1ccc(C)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C18 compound treatment 0.261 0.0113 0.61 0.6096 1.0 2060695 Enamine_000414 CSc1ncc(Cl)c(n1)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C19 compound treatment 0.261 0.0113 0.61 0.6096 1.0 2060696 Enamine_000415 CC(C)N1C(SCC1=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C20 compound treatment 0.258 0.00834 0.45 0.4484 1.0 1233605 Enamine_000416 Cc1c(oc2ccccc12)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C21 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1564604 Enamine_000417 O=C(Nc1ccccn1)C2(CCC3CC2)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C22 compound treatment 0.272 0.0223 1.2 1.2007 1.0 1196594 Enamine_000418 COc1cc2CC(=O)OC(c3ccccc3F)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C23 mock treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 C24 mock treatment 0.248 -0.00166 -0.09 -0.089 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D01 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 1406626 Enamine_000419 Fc1ccc(cc1)c2nc3C(=O)c4ccccc4C(=O)c3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D02 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 1276671 Enamine_000420 CN(C)c1ccc(CNc2nc3ccccc3n2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D03 compound treatment 0.268 0.0183 0.99 0.9858 1.0 2060697 Enamine_000421 NC1=N/C(=N/c2ccccc2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D04 compound treatment 0.356 0.106 5.71 5.7147 1.0 1727936 Enamine_000422 COc1ccc(OCCn2c(N)nc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D05 compound treatment 0.412 0.162 8.72 8.724 1.0 1144828 Enamine_000423 CCCn1c(nc2ccccc12)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D06 compound treatment 0.233 -0.0167 -0.9 -0.8951 -1.0 1204445 Enamine_000424 O=C(Nc1ccccc1)c2cc(=O)[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D07 compound treatment 0.229 -0.0207 -1.11 -1.11 -1.0 1051280 Enamine_000425 CC(=O)NC(c1ccccc1)(c2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D08 compound treatment 0.398 0.148 7.97 7.9717 1.0 1688402 Enamine_000426 COc1ccc(Cl)cc1NC(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D09 compound treatment 0.319 0.0693 3.73 3.7264 1.0 1195814 Enamine_000427 CCC(C)Nc1ncnc2c3ccccc3oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D10 compound treatment 0.256 0.00634 0.34 0.3409 1.0 1309177 Enamine_000428 OCCNc1nc2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D11 compound treatment 0.274 0.0243 1.31 1.3082 1.0 1314570 Enamine_000429 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D12 compound treatment 0.367 0.117 6.31 6.3058 1.0 2060698 Enamine_000430 Cc1cc(C[n+]2nc(sc2N)c3ccccc3)c4ncccc4c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D13 compound treatment 0.228 -0.0217 -1.16 -1.1638 -1.0 2060699 Enamine_000431 FC(F)(F)C(=O)NCC(N1CCOCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D14 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 1571928 Enamine_000432 CN(C)Cc1c(O)ccc2c(=O)c(Oc3ccccc3)coc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D15 compound treatment 0.411 0.161 8.67 8.6703 1.0 2060700 Enamine_000433 FC(F)(F)c1ccccc1N2C(=O)/C(=C\NCc3cccnc3)/c4ccccc4C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D16 compound treatment 0.31 0.0603 3.24 3.2427 1.0 1482928 Enamine_000434 CCc1ccc(cc1)C(=O)Cn2c(nc3ccccc23)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D17 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1503718 Enamine_000435 CN(C1CCS(=O)(=O)C1)C(=O)c2cccnc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D18 compound treatment 0.317 0.0673 3.62 3.6189 1.0 1400665 Enamine_000436 C(c1ccccc1)n2nnc3cnccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D19 compound treatment 0.35 0.1 5.39 5.3923 1.0 1298490 Enamine_000437 Nc1c(C#N)c2nc3ccccc3nc2n1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D20 compound treatment 0.265 0.0153 0.82 0.8245 1.0 1123680 Enamine_000438 CN(c1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D21 compound treatment 0.252 0.00234 0.13 0.1259 1.0 1740142 Enamine_000439 OC(COCc1ccccc1)CN2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D22 compound treatment 0.446 0.196 10.55 10.5511 1.0 2060701 Enamine_000440 C(Oc1ccccc1)c2cc([nH]n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D23 mock treatment 0.232 -0.0177 -0.95 -0.9488 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 D24 mock treatment 0.238 -0.0117 -0.63 -0.6264 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E01 compound treatment 0.237 -0.0127 -0.68 -0.6801 -1.0 1337165 Enamine_000441 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E02 compound treatment 0.238 -0.0117 -0.63 -0.6264 -1.0 2060702 Enamine_000442 CN1CCN(CC1)C(=O)CC2(CC3CC4CC(Br)(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E03 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1204286 Enamine_000443 CC(C)C(=O)NCc1cccnc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E04 compound treatment 0.252 0.00234 0.13 0.1259 1.0 2060703 Enamine_000444 Cn1c(c2ccccc2O)[n+](C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E05 compound treatment 0.471 0.221 11.89 11.8946 1.0 1316671 Enamine_000445 CN(C(=O)COc1cccc(Br)c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E06 compound treatment 0.252 0.00234 0.13 0.1259 1.0 2060704 Enamine_000446 Cc1cc(C)n(n1)c2nc(C)nc3sc4CCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E07 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 2060705 Enamine_000447 COc1cnc(N)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E08 compound treatment 0.337 0.0873 4.69 4.6937 1.0 2060706 Enamine_000448 COc1cccc(OC(=O)c2ccc(Cl)cc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E09 compound treatment 0.414 0.164 8.83 8.8315 1.0 1608461 Enamine_000449 CC(C)COc1cccc(OCC(=O)Nc2ccc(F)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E10 compound treatment 0.26 0.0103 0.56 0.5559 1.0 2060707 Enamine_000450 CC(=C)C(=O)Oc1ccc(NC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E11 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 2060708 Enamine_000451 CC1(C)CC(=O)C/C(=N\C2CCS(=O)(=O)C2)/C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E12 compound treatment 0.26 0.0103 0.56 0.5559 1.0 1033598 Enamine_000452 COC(=O)c1cccc(Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E13 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 2060709 Enamine_000453 COc1cccc(NC2=NCCCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E14 compound treatment 0.302 0.0523 2.81 2.8128 1.0 1664311 Enamine_000454 CCOC(=O)c1c(C)n(c2ccc(cc2)N(C)C)c3ccc(OC)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E15 compound treatment 0.25 3.44E-4 0.02 0.0185 1.0 1300742 Enamine_000455 CC12COC3(CC2CCC13C)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E16 compound treatment 0.303 0.0533 2.87 2.8666 1.0 2060710 Enamine_000456 Fc1ccccc1OC2OCCOC2Oc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E17 compound treatment 0.277 0.0273 1.47 1.4694 1.0 2060711 Enamine_000457 CC(C)C1C(C=C(Cl)Cl)C1C(=O)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E18 compound treatment 0.275 0.0253 1.36 1.3619 1.0 1272079 Enamine_000458 CSc1ncc(Cl)c(n1)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E19 compound treatment 0.315 0.0653 3.51 3.5114 1.0 1659247 Enamine_000459 Clc1ccccc1NC(=O)Cn2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E20 compound treatment 0.295 0.0453 2.44 2.4367 1.0 1734693 Enamine_000460 Cc1ccc(cc1)n2cnc3C(=O)c4ccccc4C(=O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E21 compound treatment 0.255 0.00534 0.29 0.2872 1.0 2060712 Enamine_000461 CC(C)C1CCC(C)CC1OC(=O)C[n+]2ccsc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E22 compound treatment 0.278 0.0283 1.52 1.5231 1.0 2060713 Enamine_000462 COc1ccc(/C=C(\NC(=O)c2ccccc2)/C(=O)Nc3ccc(F)cc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E23 mock treatment 0.262 0.0123 0.66 0.6633 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 E24 mock treatment 0.266 0.0163 0.88 0.8783 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F01 compound treatment 0.397 0.147 7.92 7.9179 1.0 1251809 Enamine_000463 CC1CCCC(C)N1C(=O)COc2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F02 compound treatment 0.264 0.0143 0.77 0.7708 1.0 1508653 Enamine_000464 CCn1c(NCc2ccc3OCOc3c2)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F03 compound treatment 0.265 0.0153 0.82 0.8245 1.0 1320572 Enamine_000465 COc1ccc2cc(Br)ccc2c1CC(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F04 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 2060714 Enamine_000466 Clc1ccccc1/C=C(\NC(=O)c2ccccc2)/C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F05 compound treatment 0.276 0.0263 1.42 1.4157 1.0 2060715 Enamine_000467 Cc1cc(C#N)c(C)n1c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F06 compound treatment 0.264 0.0143 0.77 0.7708 1.0 1455513 Enamine_000468 CCOc1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F07 compound treatment 0.253 0.00334 0.18 0.1797 1.0 1570033 Enamine_000469 CC(C)c1ccc(OCC(O)CNC(C)(C)C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F08 compound treatment 0.32 0.0703 3.78 3.7801 1.0 1483882 Enamine_000470 Brc1cccc(OCC(=O)NCC2CCCO2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F09 compound treatment 0.346 0.0963 5.18 5.1773 1.0 1376281 Enamine_000471 CCOC(=O)c1c(C)n(CC)c2cc(Br)c(OC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F10 compound treatment 0.382 0.132 7.11 7.1119 1.0 2060716 Enamine_000472 Cc1cc(C)c(N/C=C/2\N=C(OC2=O)c3ccccc3)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F11 compound treatment 0.282 0.0323 1.74 1.7381 1.0 2060717 Enamine_000473 Clc1ccc(CC(SC#N)C#N)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F12 compound treatment 0.244 -0.00566 -0.3 -0.304 -1.0 1092010 Enamine_000474 O=C1CCCC(=C1)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F13 compound treatment 0.294 0.0443 2.38 2.3829 1.0 1547686 Enamine_000475 O=C(Cc1ccccc1)NCC(N2CCOCC2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F14 compound treatment 0.257 0.00734 0.39 0.3946 1.0 2060718 Enamine_000476 CCCSc1nc2cc(C)c(C)cc2n1CC(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F15 compound treatment 0.396 0.146 7.86 7.8642 1.0 2060719 Enamine_000477 COc1ccc(cc1)C2=Nc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F16 compound treatment 0.252 0.00234 0.13 0.1259 1.0 1379441 Enamine_000478 O=C(Cn1c(nc2ccccc12)N3CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F17 compound treatment 0.31 0.0603 3.24 3.2427 1.0 1340359 Enamine_000479 CN(C1CCCCC1)C(=O)c2cccc(c2)S(=O)(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F18 compound treatment 0.324 0.0743 4.0 3.9951 1.0 2060720 Enamine_000480 Clc1cccc(NC(=O)/C(=C\c2cccnc2)/NC(=O)c3cccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F19 compound treatment 0.465 0.215 11.57 11.5721 1.0 1561248 Enamine_000481 Nc1c(C#N)c2nc3ccccc3nc2n1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F20 compound treatment 0.275 0.0253 1.36 1.3619 1.0 1113333 Enamine_000482 CCN(CC)S(=O)(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F21 compound treatment 0.279 0.0293 1.58 1.5769 1.0 1588571 Enamine_000483 CCOc1cc2oc(=O)c3CCCc3c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F22 compound treatment 0.31 0.0603 3.24 3.2427 1.0 1621669 Enamine_000484 CC(C)CCNC(=O)c1cccc(c1)S(=O)(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F23 mock treatment 0.26 0.0103 0.56 0.5559 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 F24 mock treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G01 compound treatment 0.283 0.0333 1.79 1.7918 1.0 2060721 Enamine_000485 Cc1cc(/N=C/c2cc(C)n(Cc3ccccc3)c2C)n(CCC#N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G02 compound treatment 0.241 -0.00866 -0.47 -0.4652 -1.0 2060722 Enamine_000486 c1nnc(o1)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G03 compound treatment 0.257 0.00734 0.39 0.3946 1.0 2060723 Enamine_000487 COc1ccc(/C=C/C(=O)Nc2ccccc2C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G04 compound treatment 0.254 0.00434 0.23 0.2334 1.0 2060724 Enamine_000488 Cc1nc2ccccc2c(=O)n1c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G05 compound treatment 0.355 0.105 5.66 5.661 1.0 1392298 Enamine_000489 Cc1ccccc1NC(=O)COc2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G06 compound treatment 0.429 0.179 9.64 9.6376 1.0 1515226 Enamine_000490 CN(C)c1ccc(NC(=O)COc2cccc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G07 compound treatment 0.286 0.0363 1.95 1.953 1.0 2060725 Enamine_000491 CC(=C(C#N)C#N)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G08 compound treatment 0.272 0.0223 1.2 1.2007 1.0 2060726 Enamine_000492 COc1ccc(/C=N/c2ccc(C)cc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G09 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 2060727 Enamine_000493 [O-][n+]1ccc(cc1)C(=O)Nc2ccccc2I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G10 compound treatment 0.254 0.00434 0.23 0.2334 1.0 1423079 Enamine_000494 CCN(CC)c1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G11 compound treatment 0.255 0.00534 0.29 0.2872 1.0 1923214 Enamine_000495 Cc1cc(cc(c1NC(=O)/C=C/C(=O)O)C(C)(C)C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G12 compound treatment 0.341 0.0913 4.91 4.9086 1.0 2060728 Enamine_000496 COc1ccc(O)c(/C=N/c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G13 compound treatment 0.254 0.00434 0.23 0.2334 1.0 2060729 Enamine_000497 ClCCCC(=O)NCc1cccnc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G14 compound treatment 0.26 0.0103 0.56 0.5559 1.0 2060730 Enamine_000498 Cc1ccccc1NC(=O)/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G15 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1396874 Enamine_000499 CC12CC3(C2CCC13C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G16 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1282161 Enamine_000500 OC(COCc1ccccc1)C[N+]2(Cc3ccccc3)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G17 compound treatment 0.297 0.0473 2.54 2.5442 1.0 2060731 Enamine_000501 C1CCc2nnc(c3ccco3)n2CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G18 compound treatment 0.292 0.0423 2.28 2.2755 1.0 1152201 Enamine_000502 COc1ccc(NS(=O)(=O)c2ccc(C)c(Cl)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G19 compound treatment 0.304 0.0543 2.92 2.9203 1.0 1344278 Enamine_000503 O=C(Cn1nnc2ccccc12)Nc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G20 compound treatment 0.256 0.00634 0.34 0.3409 1.0 1640768 Enamine_000504 CC1(C)C2(C)CCC1(OC2=O)C(=O)Nc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G21 compound treatment 0.548 0.298 16.03 16.0324 1.0 2060732 Enamine_000505 CCN1C(=O)/C(=C/c2ccc(NC(=O)C)cc2)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G22 compound treatment 0.25 3.44E-4 0.02 0.0185 1.0 1391887 Enamine_000506 COc1ccc2[nH]c(nc2c1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G23 mock treatment 0.253 0.00334 0.18 0.1797 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 G24 mock treatment 0.251 0.00134 0.07 0.0722 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H01 compound treatment 0.322 0.0723 3.89 3.8876 1.0 1705783 Enamine_000507 Clc1nc2ccccc2cc1C(=O)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H02 compound treatment 0.257 0.00734 0.39 0.3946 1.0 1217148 Enamine_000508 OC(=O)c1ccccc1N(Cc2ccccc2)C(=O)COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H03 compound treatment 0.339 0.0893 4.8 4.8011 1.0 2060733 Enamine_000509 Fc1ccc(/C=N/c2nc3ccccc3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H04 compound treatment 0.258 0.00834 0.45 0.4484 1.0 1291979 Enamine_000510 CCN(CC)CCNc1nc2cc(Cl)ccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H05 compound treatment 0.553 0.303 16.3 16.3011 1.0 1383659 Enamine_000511 Fc1ccc(cc1)C(=O)Nc2cccc(c2)c3csc(=NC(=O)c4ccc(F)cc4)[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H06 compound treatment 0.478 0.228 12.27 12.2707 1.0 1610555 Enamine_000512 CCOC(=O)c1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H07 compound treatment 0.274 0.0243 1.31 1.3082 1.0 1713817 Enamine_000513 COc1ccc(NC(=O)c2c3CCCCc3nc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H08 compound treatment 0.459 0.209 11.25 11.2497 1.0 1676393 Enamine_000514 Cc1ccc(Oc2ccc(OCC(=O)NCc3ccco3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H09 compound treatment 0.295 0.0453 2.44 2.4367 1.0 1693513 Enamine_000515 CCCCn1c(C)c(C(=O)O)c2cc(OC)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H10 compound treatment 0.442 0.192 10.34 10.3362 1.0 1477062 Enamine_000516 CNC(=O)COc1ccc(Oc2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H11 compound treatment 0.345 0.0953 5.12 5.1236 1.0 1326799 Enamine_000517 Clc1nc2ccccc2cc1C(=O)NCc3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H12 compound treatment 0.317 0.0673 3.62 3.6189 1.0 2060734 Enamine_000518 CCOc1ccc2[n+](Cc3cc(C)cc4cccnc34)c(N)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H13 compound treatment 0.517 0.267 14.37 14.3665 1.0 1418021 Enamine_000519 CN(C)C(=O)COc1ccc(Oc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H14 compound treatment 0.368 0.118 6.36 6.3595 1.0 2060735 Enamine_000520 CCCSc1nc2cc(C)c(C)cc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H15 compound treatment 0.253 0.00334 0.18 0.1797 1.0 2060736 Enamine_000521 CC(=O)OC1=C(Sc2ccc(Cl)cc2)C(=O)CCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H16 compound treatment 0.29 0.0403 2.17 2.168 1.0 1309725 Enamine_000522 CCCSc1nc2cc(C)c(C)cc2n1CC(O)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H17 compound treatment 0.26 0.0103 0.56 0.5559 1.0 1645299 Enamine_000523 Cc1ccc2c(CC(=O)O)coc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H18 compound treatment 0.3 0.0503 2.71 2.7054 1.0 1637609 Enamine_000524 C(Nc1ccccc1)c2nnc3CCCCCn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H19 compound treatment 0.554 0.304 16.35 16.3548 1.0 1217297 Enamine_000525 CCCCn1c(N)c(C#N)c2nc3ccccc3nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H20 compound treatment 0.422 0.172 9.26 9.2614 1.0 2060737 Enamine_000526 Cc1nc(C)c(s1)c2csc(Nc3ccccc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H21 compound treatment 0.256 0.00634 0.34 0.3409 1.0 1052409 Enamine_000527 CC(NC(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H22 compound treatment 0.489 0.239 12.86 12.8618 1.0 2060738 Enamine_000528 OC1(C/C(=N\n2cnnc2)/C=C1c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H23 mock treatment 0.263 0.0133 0.72 0.7171 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 H24 mock treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I01 compound treatment 0.251 0.00134 0.07 0.0722 1.0 2060739 Enamine_000529 CN(C)c1ccc(/C=N/c2ccc(cc2)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I02 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 2060740 Enamine_000530 FC(F)(F)S(=O)(=O)CCN1CCN(CC1)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I03 compound treatment 0.273 0.0233 1.25 1.2544 1.0 2060741 Enamine_000531 Clc1cc2/C(=N/c3nc4ccccc4[nH]3)/C(=O)Nc2c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I04 compound treatment 0.255 0.00534 0.29 0.2872 1.0 2060742 Enamine_000532 CC(=O)Nc1scc[n+]1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I05 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1152434 Enamine_000533 C=C1C(C1C(=O)N2CCCC2)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I06 compound treatment 0.53 0.28 15.07 15.0651 1.0 1195630 Enamine_000534 Clc1ccc(cc1)c2nc(=O)c3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I07 compound treatment 0.263 0.0133 0.72 0.7171 1.0 2060743 Enamine_000535 Cn1c(nc2ccccc12)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I08 compound treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 2060744 Enamine_000536 Cc1ccc(/N=C/c2ccc(F)cc2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I09 compound treatment 0.349 0.0993 5.34 5.3385 1.0 1596193 Enamine_000537 Cc1cc(Nc2ccccc2)nn1C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I10 compound treatment 0.345 0.0953 5.12 5.1236 1.0 1068796 Enamine_000538 CN(C)c1ccc(cc1)C(=C(C#N)C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I11 compound treatment 0.276 0.0263 1.42 1.4157 1.0 1485357 Enamine_000539 Fc1ccc2oc(cc(=O)c2c1)c3cc(Cl)cc4COCOc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I12 compound treatment 0.281 0.0313 1.68 1.6843 1.0 2060745 Enamine_000540 C/C(=C\Nc1ccccc1)/C=Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I13 compound treatment 0.25 3.44E-4 0.02 0.0185 1.0 2060746 Enamine_000541 Cc1csc(Nc2ccccc2)[n+]1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I14 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 2060747 Enamine_000542 CC(=C)C(=O)Oc1cccc(c1)N2C(=O)CCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I15 compound treatment 0.251 0.00134 0.07 0.0722 1.0 2060748 Enamine_000543 CC12CC3(C2CCC13C)C(=O)Nc4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I16 compound treatment 0.256 0.00634 0.34 0.3409 1.0 1545113 Enamine_000544 Cc1cc(ccc1N)N2OCc3ccccc3CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I17 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 1037713 Enamine_000545 Oc1ccc(cc1)C2(CCCC2)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I18 compound treatment 0.541 0.291 15.66 15.6562 1.0 1169253 Enamine_000546 CC(C)NC(=O)c1ccc2C(=O)c3ccccc3S(=O)(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I19 compound treatment 0.273 0.0233 1.25 1.2544 1.0 1670775 Enamine_000547 O=c1n(cnc2sc3CCCCc3c12)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I20 compound treatment 0.259 0.00934 0.5 0.5021 1.0 1709576 Enamine_000548 C[N+]1(Cc2nc3ccccc3[nH]2)CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I21 compound treatment 0.515 0.265 14.26 14.259 1.0 2060749 Enamine_000549 CC1C/C(=C\c2ccccn2)/C(=O)\C(=C\c3ccccn3)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I22 compound treatment 0.288 0.0383 2.06 2.0605 1.0 1640510 Enamine_000550 CCOc1cc2oc(=O)cc(C)c2cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I23 mock treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 I24 mock treatment 0.258 0.00834 0.45 0.4484 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J01 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 1475114 Enamine_000551 Clc1nc2ccccc2cc1C(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J02 compound treatment 0.282 0.0323 1.74 1.7381 1.0 1725586 Enamine_000552 CCOC(=O)c1c(NC(=O)C2CC2)scc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J03 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1438002 Enamine_000553 CC(NC(=O)c1ccc(Br)o1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J04 compound treatment 0.267 0.0173 0.93 0.932 1.0 1466643 Enamine_000554 CCOC(=O)c1c(NC(=O)c2ccccc2)sc3CCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J05 compound treatment 0.26 0.0103 0.56 0.5559 1.0 2060750 Enamine_000555 CSC(=Nc1cccc(c1)C(F)(F)F)SC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J06 compound treatment 0.26 0.0103 0.56 0.5559 1.0 1297340 Enamine_000556 COc1ccc(CNc2nc3ccccc3n2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J07 compound treatment 0.24 -0.00966 -0.52 -0.5189 -1.0 2060751 Enamine_000557 COc1nccc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J08 compound treatment 0.259 0.00934 0.5 0.5021 1.0 1272745 Enamine_000558 COc1ccc(Cc2nc3ccccc3[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J09 compound treatment 0.328 0.0783 4.21 4.21 1.0 1257788 Enamine_000559 CCc1cc(C(=O)O)c(NC(=O)c2cccc(C)c2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J10 compound treatment 0.35 0.1 5.39 5.3923 1.0 1196017 Enamine_000560 CCN1CCN(CC1)C(=O)COc2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J11 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 1156570 Enamine_000561 Clc1ccc2nc(CN3CCCCC3)cn2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J12 compound treatment 0.449 0.199 10.71 10.7123 1.0 2060752 Enamine_000562 Fc1ccc(cc1)C2=Nn3c(Cc4ccccc4)nnc3SC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J13 compound treatment 0.273 0.0233 1.25 1.2544 1.0 1215363 Enamine_000563 CSc1nc2CC(C)(C)CC(=O)c2c(c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J14 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 2060753 Enamine_000564 COC(=O)C1CCC(C(=O)O)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J15 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 1208966 Enamine_000565 COc1ccc(cc1)n2c(C)cc(=O)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J16 compound treatment 0.254 0.00434 0.23 0.2334 1.0 1349339 Enamine_000566 Cc1cccc(NC(=O)C2(CCC3(C)C(=O)O2)C3(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J17 compound treatment 0.418 0.168 9.05 9.0464 1.0 1081093 Enamine_000567 O=C1C(=Nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J18 compound treatment 0.551 0.301 16.19 16.1936 1.0 1244692 Enamine_000568 Cc1cc(C)n(n1)c2ccc(cc2)C(=O)NCCc3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J19 compound treatment 0.582 0.332 17.86 17.8595 1.0 1221523 Enamine_000569 CC(c1ccccc1)n2c(N)c(C#N)c3nc4ccccc4nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J20 compound treatment 0.309 0.0593 3.19 3.189 1.0 2060754 Enamine_000570 CCCN(CCC)S(=O)(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J21 compound treatment 0.253 0.00334 0.18 0.1797 1.0 2060755 Enamine_000571 OC(=O)CC(NC(=O)Cc1ccccc1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J22 compound treatment 0.407 0.157 8.46 8.4553 1.0 2060756 Enamine_000572 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)/C=C/c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J23 mock treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 J24 mock treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K01 compound treatment 0.276 0.0263 1.42 1.4157 1.0 1566695 Enamine_000573 CC(=O)Nc1nc2CC(C)(C)CC(=O)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K02 compound treatment 0.238 -0.0117 -0.63 -0.6264 -1.0 2060757 Enamine_000574 CCNc1ccc(cc1NC(=O)C2(CCC3CC2)C3)S(=O)(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K03 compound treatment 0.272 0.0223 1.2 1.2007 1.0 1560228 Enamine_000575 CC(NC(=O)c1ccc(Br)o1)C2CC3CCC2C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K04 compound treatment 0.487 0.237 12.75 12.7544 1.0 1316353 Enamine_000576 COc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K05 compound treatment 0.272 0.0223 1.2 1.2007 1.0 2060758 Enamine_000577 Fc1cc(C(=O)NCc2ccc(Cl)cc2)c(F)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K06 compound treatment 0.495 0.245 13.18 13.1843 1.0 2060759 Enamine_000578 CN1/C(=C\C=C(/C#N)\c2nc3ccccc3[nH]2)/C(C)(C)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K07 compound treatment 0.282 0.0323 1.74 1.7381 1.0 2060760 Enamine_000579 CCNc1ccc(cc1N)S(=O)(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K08 compound treatment 0.254 0.00434 0.23 0.2334 1.0 2060761 Enamine_000580 COc1ccc(SCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K09 compound treatment 0.276 0.0263 1.42 1.4157 1.0 1279517 Enamine_000581 O=C(N1CCc2ccccc2C1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K10 compound treatment 0.393 0.143 7.7 7.703 1.0 2060762 Enamine_000582 CCOC(=O)/C=C/c1ccc(N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K11 compound treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 1937372 Enamine_000583 Cc1c(CCO)sc[n+]1CC(=O)OC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K12 compound treatment 0.24 -0.00966 -0.52 -0.5189 -1.0 2060763 Enamine_000584 Cc1cc(=O)cc(C)n1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K13 compound treatment 0.335 0.0853 4.59 4.5862 1.0 1448502 Enamine_000585 CC1=CC(C)(C)Nc2ccc(OC(=O)Cc3ccccc3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K14 compound treatment 0.258 0.00834 0.45 0.4484 1.0 1052318 Enamine_000586 OC(=O)C1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K15 compound treatment 0.279 0.0293 1.58 1.5769 1.0 2060764 Enamine_000587 O=c1n(cnc2scc(c3ccccc3)c12)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K16 compound treatment 0.253 0.00334 0.18 0.1797 1.0 2060765 Enamine_000588 C=CC[n+]1cc(c2ccccc2)n3CCCCCc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K17 compound treatment 0.253 0.00334 0.18 0.1797 1.0 1606234 Enamine_000589 Cc1cc(=O)cc(C)n1c2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K18 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 2060766 Enamine_000590 CSc1ncc(Cl)c(n1)C(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K19 compound treatment 0.277 0.0273 1.47 1.4694 1.0 1561959 Enamine_000591 CCC(=O)Nc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K20 compound treatment 0.261 0.0113 0.61 0.6096 1.0 1044631 Enamine_000592 Cc1ccc(SCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K21 compound treatment 0.332 0.0823 4.42 4.425 1.0 1476053 Enamine_000593 CC(C)CCOc1cccc(OCC(=O)NCC2CCCO2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K22 compound treatment 0.268 0.0183 0.99 0.9858 1.0 1489112 Enamine_000594 CC(=O)Oc1ccc(cc1C)c2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K23 mock treatment 0.253 0.00334 0.18 0.1797 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 K24 mock treatment 0.263 0.0133 0.72 0.7171 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L01 compound treatment 0.24 -0.00966 -0.52 -0.5189 -1.0 1326202 Enamine_000595 Clc1ccc(CNC(=O)c2cc3ccccc3nc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L02 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 1328604 Enamine_000596 OC(=O)c1ccccc1N(Cc2ccccc2)C(=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L03 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 1324703 Enamine_000597 CCN1CCN(CC1)C(=O)c2ccc(Cl)nc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L04 compound treatment 0.465 0.215 11.57 11.5721 1.0 1620483 Enamine_000598 NC1=C(C#N)C(c2sc3ccccc3c2O1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L05 compound treatment 0.33 0.0803 4.32 4.3175 1.0 2060767 Enamine_000599 CC(=O)Oc1cc2oc(=O)cc(C)c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L06 compound treatment 0.468 0.218 11.73 11.7333 1.0 1920374 Enamine_000600 COc1ccc(NC(=O)c2ccc(Br)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L07 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1645228 Enamine_000601 CC1CCCN(C1)C(=O)c2ccc(Cl)nc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L08 compound treatment 0.257 0.00734 0.39 0.3946 1.0 2060768 Enamine_000602 Cc1ccccc1Oc2ccc(Oc3ccccc3C)nn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L09 compound treatment 0.356 0.106 5.71 5.7147 1.0 1694610 Enamine_000603 Nc1ccc2n(CCCn3cnc4cc(N)ccc34)cnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L10 compound treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 2060769 Enamine_000604 CC1(C)CNC(=O)C=C(C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L11 compound treatment 0.256 0.00634 0.34 0.3409 1.0 2060770 Enamine_000605 Cc1c(CCOC(=O)C2CC2)sc[n+]1CC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L12 compound treatment 0.304 0.0543 2.92 2.9203 1.0 1173196 Enamine_000606 Nc1ncc(Cc2cccc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L13 compound treatment 0.431 0.181 9.75 9.745 1.0 2060771 Enamine_000607 Brc1ccc2oc(=N)c(cc2c1)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L14 compound treatment 0.256 0.00634 0.34 0.3409 1.0 1726203 Enamine_000608 O=C(C1CC2CCCC(C1)C2=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L15 compound treatment 0.482 0.232 12.49 12.4857 1.0 1513313 Enamine_000609 Cc1ccc(cc1)C(=O)CSc2nc(=O)cc(C)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L16 compound treatment 0.295 0.0453 2.44 2.4367 1.0 1603883 Enamine_000610 OC(NC(=O)c1ccccn1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L17 compound treatment 0.473 0.223 12.0 12.002 1.0 1725950 Enamine_000611 CCC(=O)Nc1c(C#N)c2nc3ccccc3nc2n1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L18 compound treatment 0.343 0.0933 5.02 5.0161 1.0 1171448 Enamine_000612 Cc1c(O)ccc2c(=O)c(coc12)c3ccc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L19 compound treatment 0.282 0.0323 1.74 1.7381 1.0 2060772 Enamine_000613 FC(F)(F)C(=O)NCSc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L20 compound treatment 0.54 0.29 15.6 15.6025 1.0 2060773 Enamine_000614 COc1ccccc1N/C=C\2/Sc3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L21 compound treatment 0.276 0.0263 1.42 1.4157 1.0 2060774 Enamine_000615 O=C/1CCCC\C1=C/Nc2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L22 compound treatment 0.28 0.0303 1.63 1.6306 1.0 2060775 Enamine_000616 Oc1ccccc1/N=C/c2sc3ccccc3c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L23 mock treatment 0.255 0.00534 0.29 0.2872 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 L24 mock treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M01 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 2060776 Enamine_000617 OC(=O)Cc1cc(on1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M02 compound treatment 0.25 3.44E-4 0.02 0.0185 1.0 2060777 Enamine_000618 Cn1c(c2ccco2)[n+](C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M03 compound treatment 0.24 -0.00966 -0.52 -0.5189 -1.0 1415193 Enamine_000619 CC1CCc2ccccc2N1C(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M04 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 2060778 Enamine_000620 CNC(=O)/C=C/1\N(C)c2ccccc2C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M05 compound treatment 0.23 -0.0197 -1.06 -1.0563 -1.0 2060779 Enamine_000621 Cc1ccc(C)c(NC2=NCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M06 compound treatment 0.248 -0.00166 -0.09 -0.089 -1.0 1208942 Enamine_000622 CC1(C)CC(C)(c2ccccc2)c3cccc4CC(=O)N1c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M07 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 1678743 Enamine_000623 NC(=O)C(=C1CCCCCC1)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M08 compound treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 1626998 Enamine_000624 CC1(C)C(CCC1(C)C(=O)O)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M09 compound treatment 0.257 0.00734 0.39 0.3946 1.0 2060780 Enamine_000625 Cc1ccc(NC(=O)CC2(OCCO2)C(F)(F)F)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M10 compound treatment 0.254 0.00434 0.23 0.2334 1.0 3048206 Enamine_000626 C[N+](C)(C)Cc1ccccc1.OC(=O)c1ccccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M11 compound treatment 0.262 0.0123 0.66 0.6633 1.0 2060781 Enamine_000627 COc1ccc(NC(=O)C2C(C(=O)Nc3ccc(OC)cc3)C2=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M12 compound treatment 0.321 0.0713 3.83 3.8339 1.0 1195895 Enamine_000628 COc1ccc2n(c(C)c(C(=O)O)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M13 compound treatment 0.472 0.222 11.95 11.9483 1.0 1139797 Enamine_000629 CCc1ccc(OCC(=O)N2CC(C)OC(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M14 compound treatment 0.252 0.00234 0.13 0.1259 1.0 2060782 Enamine_000630 Nc1cccc(/C=C/C(=O)O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M15 compound treatment 0.378 0.128 6.9 6.8969 1.0 2060783 Enamine_000631 CC(=O)N1C(=O)/C(=C\C(=O)c2ccc(C)cc2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M16 compound treatment 0.251 0.00134 0.07 0.0722 1.0 2060784 Enamine_000632 O=C(C[n+]1cc(c2ccccc2)n3CCCc31)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M17 compound treatment 0.266 0.0163 0.88 0.8783 1.0 1239678 Enamine_000633 CCN1CCN(CC1)C(=O)c2ccc(I)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M18 compound treatment 0.307 0.0573 3.08 3.0815 1.0 1697263 Enamine_000634 CSC1=C(C#N)C2(CCCC2)C(C#N)C(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M19 compound treatment 0.311 0.0613 3.3 3.2965 1.0 2060785 Enamine_000635 COc1ccc(cc1)C2SCC(=O)N2c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M20 compound treatment 0.264 0.0143 0.77 0.7708 1.0 2060786 Enamine_000636 c1nc(c(s1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M21 compound treatment 0.278 0.0283 1.52 1.5231 1.0 1564874 Enamine_000637 COc1cccc(OCC(=O)NCC2CCCO2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M22 compound treatment 0.271 0.0213 1.15 1.147 1.0 1568000 Enamine_000638 CN(C)c1ccc(CNc2nc3ccccc3n2CCN4CCCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M23 mock treatment 0.254 0.00434 0.23 0.2334 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 M24 mock treatment 0.257 0.00734 0.39 0.3946 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N01 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 1422077 Enamine_000639 C[N+]1(Cc2cn3ccccc3n2)CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N02 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1339471 Enamine_000640 OC(=O)c1ccccc1N(Cc2ccccc2)C(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N03 compound treatment 0.285 0.0353 1.9 1.8993 1.0 1576596 Enamine_000641 Nc1nc2ccccc2n1Cc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N04 compound treatment 0.269 0.0193 1.04 1.0395 1.0 1691589 Enamine_000642 CCn1c(NCc2cccs2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N05 compound treatment 0.491 0.241 12.97 12.9693 1.0 2060787 Enamine_000643 ClCCCC(=O)Nc1ncnc2n(ncc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N06 compound treatment 0.337 0.0873 4.69 4.6937 1.0 2060788 Enamine_000644 Cc1cccnc1N/C=C/2\C(=O)N(C(=O)c3ccccc23)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N07 compound treatment 0.27 0.0203 1.09 1.0932 1.0 1368892 Enamine_000645 Cc1ccccc1Oc2ncnc3sc4CCCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N08 compound treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 1718640 Enamine_000646 OC(=O)c1ccccc1C(=O)N2CC(=O)Nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N09 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1427587 Enamine_000647 COc1cc(Br)c(CC(=O)N2CCOCC2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N10 compound treatment 0.341 0.0913 4.91 4.9086 1.0 1475244 Enamine_000648 Cc1cc(NC(=O)COc2ccccc2)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N11 compound treatment 0.371 0.121 6.52 6.5208 1.0 2060789 Enamine_000649 CN1/C(=C\C=C2C(=O)c3ccccc3C2=O)/Sc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N12 compound treatment 0.307 0.0573 3.08 3.0815 1.0 2060790 Enamine_000650 FC(F)(F)c1cccc(NC(=O)/C(=C\c2cccnc2)/NC(=O)c3cccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N13 compound treatment 0.265 0.0153 0.82 0.8245 1.0 2060791 Enamine_000651 FC(F)(F)S(=O)(=O)c1ccc(Cl)c(NC(=O)COc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N14 compound treatment 0.235 -0.0147 -0.79 -0.7876 -1.0 2060792 Enamine_000652 CNC1=N/C(=N\C)/c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N15 compound treatment 0.479 0.229 12.32 12.3245 1.0 1637442 Enamine_000653 C1Cc2ncc(c3ccc4OCCOc4c3)n2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N16 compound treatment 0.252 0.00234 0.13 0.1259 1.0 2060793 Enamine_000654 CC1SC(=O)N(C1=O)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N17 compound treatment 0.25 3.44E-4 0.02 0.0185 1.0 1187240 Enamine_000655 O=C(N(c1ccccn1)c2ccccn2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N18 compound treatment 0.256 0.00634 0.34 0.3409 1.0 1339910 Enamine_000656 Fc1cc(Cl)c(cc1F)C(=O)C(C#N)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N19 compound treatment 0.272 0.0223 1.2 1.2007 1.0 2060794 Enamine_000657 FC(F)(F)C(=O)NCSc1nc2ccccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N20 compound treatment 0.261 0.0113 0.61 0.6096 1.0 1155410 Enamine_000658 CCOc1ccc(NC2=CC(=O)CC(C)(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N21 compound treatment 0.257 0.00734 0.39 0.3946 1.0 2060795 Enamine_000659 NC(CC(=O)O)c1ccccc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N22 compound treatment 0.272 0.0223 1.2 1.2007 1.0 2060796 Enamine_000660 O=C1CCCC(=C1)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N23 mock treatment 0.249 -6.56E-4 -0.04 -0.0353 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 N24 mock treatment 0.241 -0.00866 -0.47 -0.4652 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O01 compound treatment 0.243 -0.00666 -0.36 -0.3577 -1.0 1335831 Enamine_000661 Clc1ccc(NCC(=O)c2cc3ccccc3oc2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O02 compound treatment 0.244 -0.00566 -0.3 -0.304 -1.0 2060797 Enamine_000662 Cn1c(c2ccccn2)[n+](C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O03 compound treatment 0.259 0.00934 0.5 0.5021 1.0 2060798 Enamine_000663 CC(C)C(=O)Nc1ncc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O04 compound treatment 0.39 0.14 7.54 7.5418 1.0 2060799 Enamine_000664 CN1C/C(=C\c2ccccc2F)/C(=O)\C(=C\c3ccccc3F)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O05 compound treatment 0.241 -0.00866 -0.47 -0.4652 -1.0 1666153 Enamine_000665 CC1(CCCC1)C(=O)Nc2ccc(NC(=O)C3(C)CCCC3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O06 compound treatment 0.246 -0.00366 -0.2 -0.1965 -1.0 2060800 Enamine_000666 CCN1CCN(CC1)C(=O)c2cc[n+]([O-])cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O07 compound treatment 0.266 0.0163 0.88 0.8783 1.0 1480394 Enamine_000667 Cc1cccc(c1)C(=O)Cc2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O08 compound treatment 0.296 0.0463 2.49 2.4904 1.0 1486441 Enamine_000668 Cc1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O09 compound treatment 0.254 0.00434 0.23 0.2334 1.0 1259057 Enamine_000669 CNc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O10 compound treatment 0.264 0.0143 0.77 0.7708 1.0 2060801 Enamine_000670 N#CC(=C(Nc1ccccc1)c2ccccc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O11 compound treatment 0.252 0.00234 0.13 0.1259 1.0 1702551 Enamine_000671 CC(NC(=O)c1cccs1)C2CC3CCC2C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O12 compound treatment 0.242 -0.00766 -0.41 -0.4114 -1.0 2060802 Enamine_000672 Fc1ccc(cc1)c2nc3sc4CCCCc4c3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O13 compound treatment 0.535 0.285 15.33 15.3338 1.0 1661874 Enamine_000673 O=C(COc1ccccc1)N2CCCC3CCCCC32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O14 compound treatment 0.313 0.0633 3.4 3.404 1.0 2060803 Enamine_000674 C1CC(C=C1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O15 compound treatment 0.266 0.0163 0.88 0.8783 1.0 2060804 Enamine_000675 C1CCC(CC1)Nc2nc(c3ccccc3)[n+](s2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O16 compound treatment 0.262 0.0123 0.66 0.6633 1.0 1590768 Enamine_000676 CN1C(=CC(c2ccccc2)n3ncnc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O17 compound treatment 0.275 0.0253 1.36 1.3619 1.0 1388672 Enamine_000677 CCN1CCN(CC1)C(=O)c2ccc(Br)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O18 compound treatment 0.268 0.0183 0.99 0.9858 1.0 1498187 Enamine_000678 C1CCC2=C(C1)Nc3ncnn3C2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O19 compound treatment 0.266 0.0163 0.88 0.8783 1.0 2060805 Enamine_000679 CCSC1=C(C#N)C(C)C(C#N)C(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O20 compound treatment 0.258 0.00834 0.45 0.4484 1.0 1502514 Enamine_000680 CCN1CCN(CC1)C(=O)Cc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O21 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1270508 Enamine_000681 OC(=O)c1ccccc1C(=O)c2cc(Cl)ccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O22 compound treatment 0.329 0.0793 4.26 4.2638 1.0 1671107 Enamine_000682 COc1ccc(NC(=O)c2ccc(O)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O23 mock treatment 0.25 3.44E-4 0.02 0.0185 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 O24 mock treatment 0.247 -0.00266 -0.14 -0.1427 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P01 compound treatment 0.24 -0.00966 -0.52 -0.5189 -1.0 2060806 Enamine_000683 CN(C)C(=O)n1nc2-c3ccccc3C(=O)c4cccc1c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P02 compound treatment 0.273 0.0233 1.25 1.2544 1.0 1287089 Enamine_000684 OC(=O)c1ccccc1NCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P03 compound treatment 0.251 0.00134 0.07 0.0722 1.0 1494283 Enamine_000685 CCC(C)CNC(=O)c1ccc(OC)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P04 compound treatment 0.274 0.0243 1.31 1.3082 1.0 2060807 Enamine_000686 O=C(NCCCn1ccnc1)c2cn(nc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P05 compound treatment 0.262 0.0123 0.66 0.6633 1.0 1728248 Enamine_000687 Cc1ccc(Cn2c(N)nc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P06 compound treatment 0.4 0.15 8.08 8.0792 1.0 2060808 Enamine_000688 Cc1cc(N/C=C/2\CCCCC2=O)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P07 compound treatment 0.235 -0.0147 -0.79 -0.7876 -1.0 1506446 Enamine_000689 Cc1cc(C)cc(OCC(O)CNC(C)(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P08 compound treatment 0.236 -0.0137 -0.73 -0.7339 -1.0 1640910 Enamine_000690 COc1ccc(NC2(CCCCC2)C(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P09 compound treatment 0.448 0.198 10.66 10.6586 1.0 2060809 Enamine_000691 CC(C)Cc1csc(NC(=O)/C=C/c2ccccc2)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P10 compound treatment 0.257 0.00734 0.39 0.3946 1.0 1199030 Enamine_000692 CN(C)c1cccc(NC(=O)c2ccncc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P11 compound treatment 0.293 0.0433 2.33 2.3292 1.0 1615580 Enamine_000693 CCN1C(=O)c2cccc3c(NC(=O)C4CCCCC4)ccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P12 compound treatment 0.456 0.206 11.09 11.0885 1.0 1477710 Enamine_000694 Cc1ccc(cc1)C(=O)Oc2ccc3n(C)cnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P13 compound treatment 0.298 0.0483 2.6 2.5979 1.0 2060810 Enamine_000695 Cc1cc(OC(=O)c2ccc(Br)cc2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P14 compound treatment 0.245 -0.00466 -0.25 -0.2502 -1.0 1176285 Enamine_000696 O=C(Nc1nccs1)C2CC3CCCC(C2)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P15 compound treatment 0.392 0.142 7.65 7.6493 1.0 2060811 Enamine_000697 Cn1c(CO)nc2cc(/N=C/c3ccccc3O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P16 compound treatment 0.24 -0.00966 -0.52 -0.5189 -1.0 1584077 Enamine_000698 CC(C(O)c1ccccc1)N(C)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P17 compound treatment 0.275 0.0253 1.36 1.3619 1.0 1109084 Enamine_000699 CCOC(=O)c1c(C)cc2ccccn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P18 compound treatment 0.491 0.241 12.97 12.9693 1.0 1505629 Enamine_000700 N#Cc1nc(oc1NCc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P19 compound treatment 0.225 -0.0247 -1.32 -1.325 -1.0 1315152 Enamine_000701 O=C(NC1C2CC3CC(C2)CC1C3)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P20 compound treatment 0.345 0.0953 5.12 5.1236 1.0 1449715 Enamine_000702 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)COc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P21 compound treatment 0.239 -0.0107 -0.57 -0.5726 -1.0 1534526 Enamine_000703 Clc1ccc(cc1Cl)C(=O)N(c2ccccn2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P22 compound treatment 0.244 -0.00566 -0.3 -0.304 -1.0 1261225 Enamine_000704 CCOc1ccc(NC(=O)c2cc(Cl)nc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P23 mock treatment 0.255 0.00534 0.29 0.2872 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.1395 P24 mock treatment 0.241 -0.00866 -0.47 -0.4652 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A01 compound treatment 0.269 0.0157 0.84 0.843 1.0 3118959 ChemDiv3_003873 COC(=O)C(CC(C)C)N1C=C(C(C(=C1)C(=O)OC)c2ccc(Br)cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A02 compound treatment 0.241 -0.0123 -0.66 -0.6616 -1.0 3023755 ChemDiv3_003874 CN(C)c1ccc(cc1)n2cccc2C=C3C(=O)N(C)C(=S)N(C)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A03 compound treatment 0.263 0.00969 0.52 0.5206 1.0 1344150 ChemDiv3_003875 CSc1nnc-2c(OC(C)Nc3ccccc32)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A04 compound treatment 0.354 0.101 5.41 5.4107 1.0 3118960 ChemDiv3_003876 O=C(CSc1nnc(COc2ccccc2)o1)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A05 compound treatment 0.359 0.106 5.68 5.6794 1.0 3023867 ChemDiv3_003877 CCc1ccc2NC(=O)/C(=C/3\SC(=N)NC3=O)/c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A06 compound treatment 0.234 -0.0193 -1.04 -1.0378 -1.0 1867181 ChemDiv3_003878 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CNC(C)(C)C)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A07 compound treatment 0.255 0.00169 0.09 0.0907 1.0 3118961 ChemDiv3_003879 CCc1ccc(/C=N/n2c(C)nnc2n3nc(C)cc3C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A08 compound treatment 0.244 -0.00931 -0.5 -0.5004 -1.0 1292139 ChemDiv3_003880 O=C(N1c2ccccc2Sc3ccccc13)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A09 compound treatment 0.28 0.0267 1.43 1.4341 1.0 3119097 ChemDiv3_003881 CN1C(=O)/C(=C/2\S\C(=N/c3ccc(F)cc3)\NC2=O)/c4cc(Br)cc(C)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A10 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3023868 ChemDiv3_003882 CCCn1c(C)cc(C)c(C#N)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A11 compound treatment 0.285 0.0317 1.7 1.7028 1.0 3023869 ChemDiv3_003883 CC(Cc1ccccc1)[n+]2[cH-]/c(=N\C(=O)N)/on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A12 compound treatment 0.263 0.00969 0.52 0.5206 1.0 1249817 ChemDiv3_003884 COc1cccc(CN2CCN(CC2)C(=O)c3cccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A13 compound treatment 0.331 0.0777 4.17 4.1748 1.0 3119098 ChemDiv3_003885 Cc1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)NCC4CCCO4)c5ccccc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A14 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3023870 ChemDiv3_003886 C(Cc1c[nH]c2ccccc12)NCc3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A15 compound treatment 0.46 0.207 11.11 11.107 1.0 1549146 ChemDiv3_003887 Clc1ccc(SCC(=O)Nc2ccc(cc2)c3nc4ncccc4o3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A16 compound treatment 0.245 -0.00831 -0.45 -0.4467 -1.0 3023871 ChemDiv3_003888 CCCN(CCC)C1=C(N(CC(=O)N)S(=O)(=O)c2ccccc12)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A17 compound treatment 0.267 0.0137 0.74 0.7355 1.0 1118860 ChemDiv3_003889 CCN(CC)CCC(=O)N1N=C(CC1c2ccc(OC)cc2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A18 compound treatment 0.257 0.00369 0.2 0.1982 1.0 1173412 ChemDiv3_003890 Cc1cc(C)cc(Oc2coc3cc(OCC(=O)NCc4ccccc4)ccc3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A19 compound treatment 0.261 0.00769 0.41 0.4131 1.0 1387978 ChemDiv3_003891 CN(C)C1CS(=O)(=O)CC1N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A20 compound treatment 0.329 0.0757 4.07 4.0673 1.0 1867723 ChemDiv3_003892 COc1ccccc1COc2ccc3c4CCCCCc4c(=O)oc3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A21 compound treatment 0.249 -0.00431 -0.23 -0.2317 -1.0 1361724 ChemDiv3_003893 O=C(NCc1ccccc1)NC2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A22 compound treatment 0.504 0.251 13.47 13.4714 1.0 1233165 ChemDiv3_003894 Cc1oc(cc1COc2ccc3c(C)c(Cc4ccccc4)c(=O)oc3c2C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A23 mock treatment 0.254 6.88E-4 0.04 0.0369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 A24 mock treatment 0.243 -0.0103 -0.55 -0.5542 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B01 compound treatment 0.307 0.0537 2.89 2.8851 1.0 3119099 ChemDiv3_003895 CN(/N=C/c1ccccc1)C2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B02 compound treatment 0.519 0.266 14.28 14.2775 1.0 3119100 ChemDiv3_003896 COC(=O)C1=C(C)N/C(=C/c2cc(C)n(c2C)c3ccc(OC)c(Cl)c3)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B03 compound treatment 0.282 0.0287 1.54 1.5416 1.0 3023872 ChemDiv3_003897 COc1cccc(C=C2C(=O)c3ccccc3C2=O)c1OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B04 compound treatment 0.278 0.0247 1.33 1.3267 1.0 3023873 ChemDiv3_003898 Cc1ccc(cc1)c2c[n+]([O-])c3CCCc3[n+]2[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B05 compound treatment 0.612 0.359 19.28 19.2751 1.0 3119101 ChemDiv3_003899 O=c1[nH]c2ccccc2n1CCCSc3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B06 compound treatment 0.383 0.13 6.97 6.9691 1.0 1401658 ChemDiv3_003900 CCOC(=O)c1c(oc2ccc(OCC(=O)OC)cc12)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B07 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1210771 ChemDiv3_003901 CC(C)Cn1c(=O)c2cc3c(=O)n(CC(C)C)c(=O)c3c(C(=O)c4ccc(Cl)cc4)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B08 compound treatment 0.46 0.207 11.11 11.107 1.0 1511593 ChemDiv3_003902 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B09 compound treatment 0.259 0.00569 0.31 0.3056 1.0 1487762 ChemDiv3_003903 O=S(=O)(NCCC1(CC2CC3CC(C2)C1)C3)c4cccc5nsnc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B10 compound treatment 0.494 0.241 12.93 12.934 1.0 3023874 ChemDiv3_003904 COc1cc(/C=C\2/C(=N)N3C=CSC3=NC2=O)cc(OC)c1OCCOc4ccc(C)c(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B11 compound treatment 0.321 0.0677 3.64 3.6374 1.0 3119102 ChemDiv3_003905 CN(C)/C=N/c1c(C#N)cnn1c2ncnc3sc4CCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B12 compound treatment 0.4 0.147 7.88 7.8827 1.0 3023875 ChemDiv3_003906 COc1ccc2N3C(=NC(=O)C(Cc4ccccc4)C3=O)Sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B13 compound treatment 0.271 0.0177 0.95 0.9505 1.0 1072961 ChemDiv3_003907 O=c1n(Cc2ccccc2)nc(c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B14 compound treatment 0.333 0.0797 4.28 4.2822 1.0 1739914 ChemDiv3_003908 Clc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B15 compound treatment 0.478 0.225 12.07 12.0742 1.0 3023876 ChemDiv3_003909 C(Sc1nc2ccccc2[nH]1)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B16 compound treatment 0.434 0.181 9.71 9.7098 1.0 1325550 ChemDiv3_003910 NC1=C(C#N)C(c2sc3ccccc3c2O1)c4ccccc4OC(=O)c5ccccc5Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B17 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3023877 ChemDiv3_003911 CC(C)OC(=O)C1=c2s/c(=C\c3cccnc3)/c(=O)n2C(=C(C#N)C1c4cccnc4)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B18 compound treatment 0.3 0.0467 2.51 2.5089 1.0 3119103 ChemDiv3_003912 COc1ccc(CN2C(=O)CC(Cc3ccc(C)cc3)C2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B19 compound treatment 0.476 0.223 11.97 11.9668 1.0 1408601 ChemDiv3_003913 COc1ccc(CCNc2ncnc3sc4CCCCc4c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B20 compound treatment 0.505 0.252 13.53 13.5252 1.0 3023878 ChemDiv3_003914 N=C1NC(=O)/C(=C\c2cc3ccccc3nc2N4CCCCC4)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B21 compound treatment 0.248 -0.00531 -0.29 -0.2855 -1.0 1543973 ChemDiv3_003915 COc1ccc2CNCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B22 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3119104 ChemDiv3_003916 CC1CCN(CN2CC(COc3ccccc3C)OC2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B23 mock treatment 0.237 -0.0163 -0.88 -0.8766 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 B24 mock treatment 0.238 -0.0153 -0.82 -0.8229 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C01 compound treatment 0.25 -0.00331 -0.18 -0.178 -1.0 3119105 ChemDiv3_003917 COC(=O)C1=CN(C=C(C1c2ccsc2)C(=O)OC)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C02 compound treatment 0.285 0.0317 1.7 1.7028 1.0 3023910 ChemDiv3_003918 Cn1c(=O)n(C)c2cc(/C=C/3\C(=O)NC(=S)N(CC=C)C3=O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C03 compound treatment 0.264 0.0107 0.57 0.5743 1.0 3119106 ChemDiv3_003919 CSC1=N/C(=C\c2ccccc2C)/C(=O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C04 compound treatment 0.474 0.221 11.86 11.8593 1.0 3119107 ChemDiv3_003920 COc1ccc(CCCc2nnc(SCC(=O)Nc3cc(F)ccc3C)o2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C05 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3023911 ChemDiv3_003921 C=CCN1C(=O)/C(=C/2\S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)/c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C06 compound treatment 0.268 0.0147 0.79 0.7893 1.0 1871099 ChemDiv3_003922 Cc1cccc(c1)N2C(=O)CC(Sc3nccc(C)n3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C07 compound treatment 0.369 0.116 6.22 6.2168 1.0 3023912 ChemDiv3_003923 CSC1=N/C(=C\C=C\c2cccs2)/C(=O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C08 compound treatment 0.302 0.0487 2.62 2.6164 1.0 1871152 ChemDiv3_003924 O=C(Cc1cccs1)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C09 compound treatment 0.302 0.0487 2.62 2.6164 1.0 3023913 ChemDiv3_003925 CCSC1=N/C(=C\c2ccc(C)s2)/C(=O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C10 compound treatment 0.292 0.0387 2.08 2.079 1.0 3119108 ChemDiv3_003926 CCCN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C(=C(C#N)C1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C11 compound treatment 0.259 0.00569 0.31 0.3056 1.0 3023914 ChemDiv3_003927 N=c1[cH-][n+](CCc2ccccc2)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C12 compound treatment 0.396 0.143 7.67 7.6677 1.0 1216628 ChemDiv3_003928 CCOc1cc(CN2CCN(CC2)C(=O)COc3ccc(C)cc3)ccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C13 compound treatment 0.417 0.164 8.8 8.7962 1.0 3023915 ChemDiv3_003929 COc1ccc(cc1)c2nnc(Nc3cccc(c3)C(F)(F)F)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C14 compound treatment 0.294 0.0407 2.19 2.1865 1.0 3119109 ChemDiv3_003930 COc1cccc(CNCCc2c[nH]c3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C15 compound treatment 0.277 0.0237 1.27 1.2729 1.0 1485768 ChemDiv3_003931 CCC(=O)NC(c1ccco1)c2cc(Cl)c3cccnc3c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C16 compound treatment 0.277 0.0237 1.27 1.2729 1.0 1522564 ChemDiv3_003932 Cc1nc(NCCN2CCOCC2)c3sc4nc5CC(C)(C)OCc5cc4c3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C17 compound treatment 0.422 0.169 9.06 9.0649 1.0 3119239 ChemDiv3_003933 COc1ccc(cc1)C2CC(=NN2C(=O)CCN3CCOCC3)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C18 compound treatment 0.375 0.122 6.54 6.5392 1.0 1139781 ChemDiv3_003934 CC(C)COC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C19 compound treatment 0.268 0.0147 0.79 0.7893 1.0 1505314 ChemDiv3_003935 O=S1(=O)CCC(C1)N2C(=S)SC3CS(=O)(=O)C=C32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C20 compound treatment 0.516 0.263 14.12 14.1163 1.0 1867708 ChemDiv3_003936 COc1cc(COc2ccc3c4CCCc4c(=O)oc3c2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C21 compound treatment 0.281 0.0277 1.49 1.4879 1.0 1172275 ChemDiv3_003937 CC1(CCS(=O)(=O)C1)NC(=S)Nc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C22 compound treatment 0.284 0.0307 1.65 1.6491 1.0 1132860 ChemDiv3_003938 CN(C)C(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C23 mock treatment 0.254 6.88E-4 0.04 0.0369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 C24 mock treatment 0.259 0.00569 0.31 0.3056 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D01 compound treatment 0.41 0.157 8.42 8.4201 1.0 3023916 ChemDiv3_003939 O=S1(=O)N=C(N(CCC#N)/N=C/c2ccccc2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D02 compound treatment 0.344 0.0907 4.87 4.8734 1.0 3119240 ChemDiv3_003940 COC(=O)C/1=C(C)NC(=O)\C1=C\c2ccc(CNS(=O)(=O)c3ccc(Cl)cc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D03 compound treatment 0.407 0.154 8.26 8.2588 1.0 3023917 ChemDiv3_003941 CCC(C)N1C(=O)S/C(=C/c2ccc3n(C)c(=O)n(C)c3c2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D04 compound treatment 0.265 0.0117 0.63 0.6281 1.0 3119241 ChemDiv3_003942 [O-][n+]1cc(c2ccc(F)cc2)[n+]([O-])c3CCCc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D05 compound treatment 0.319 0.0657 3.53 3.5299 1.0 3119242 ChemDiv3_003943 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3sc4CCCCc4c3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D06 compound treatment 0.275 0.0217 1.17 1.1654 1.0 3023918 ChemDiv3_003944 CCCCc1c(O)nc(SCC(=O)N2CCCCC2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D07 compound treatment 0.465 0.212 11.38 11.3756 1.0 3119243 ChemDiv3_003945 COc1ccccc1CC(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D08 compound treatment 0.278 0.0247 1.33 1.3267 1.0 3023919 ChemDiv3_003946 OC(Cn1c2ccccc2c3ccccc13)C[n+]4cccc5cccc(O)c45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D09 compound treatment 0.423 0.17 9.12 9.1187 1.0 3119244 ChemDiv3_003947 Nc1nc(SCC(=O)NCc2ccco2)c(C#N)cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D10 compound treatment 0.321 0.0677 3.64 3.6374 1.0 3119245 ChemDiv3_003948 COc1ccccc1N(C(=O)NCc2ccccc2)C3=NCC(C)S3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D11 compound treatment 0.286 0.0327 1.76 1.7566 1.0 1494926 ChemDiv3_003949 Cc1ccc(cc1)c2nnc(n3cnc4cc(C)c(C)cc34)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D12 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1647264 ChemDiv3_003950 CCc1nc2oc(C(=O)c3ccccc3)c(N)c2c4CC(C)(C)OCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D13 compound treatment 0.265 0.0117 0.63 0.6281 1.0 1516394 ChemDiv3_003951 Cc1nc(Oc2ccc(NC(=O)c3ccccc3)cc2)c4c5CCCc5sc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D14 compound treatment 0.341 0.0877 4.71 4.7121 1.0 1736266 ChemDiv3_003952 CCc1ccc(Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(C)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D15 compound treatment 0.261 0.00769 0.41 0.4131 1.0 1623664 ChemDiv3_003953 C(N1CCc2ccccc2C1)n3cnc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D16 compound treatment 0.321 0.0677 3.64 3.6374 1.0 1684726 ChemDiv3_003954 COc1ccccc1NC(=O)COc2ccc3oc4CCCCc4c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D17 compound treatment 0.272 0.0187 1.0 1.0042 1.0 1574911 ChemDiv3_003955 NC1=C(C#N)C2(C(=O)N(CC=C)c3ccccc32)c4c(O1)c5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D18 compound treatment 0.277 0.0237 1.27 1.2729 1.0 1249386 ChemDiv3_003956 O=C1CC(Cc2ccccc2)C(=O)N1c3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D19 compound treatment 0.418 0.165 8.85 8.85 1.0 1153670 ChemDiv3_003957 Cc1sc2nc3c4ccccc4c(NCC5CCCO5)nn3c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D20 compound treatment 0.448 0.195 10.46 10.4621 1.0 3119246 ChemDiv3_003958 CC(=O)N1C(=N)S/C(=C/c2cc3ccccc3nc2Sc4ccccc4)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D21 compound treatment 0.506 0.253 13.58 13.5789 1.0 1736305 ChemDiv3_003959 CC(C)COc1ccc2c3CCCCc3c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D22 compound treatment 0.29 0.0367 1.97 1.9715 1.0 3023957 ChemDiv3_003960 CC1CCN(CN2CC(Cn3c4ccccc4c5ccccc35)OC2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D23 mock treatment 0.252 -0.00131 -0.07 -0.0705 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 D24 mock treatment 0.254 6.88E-4 0.04 0.0369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E01 compound treatment 0.263 0.00969 0.52 0.5206 1.0 3119247 ChemDiv3_003961 COC(=O)CN1C=C(C(C(=C1)C(=O)OC)c2ccc(O)cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E02 compound treatment 0.318 0.0647 3.48 3.4762 1.0 3119248 ChemDiv3_003962 CCC(C)n1cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E03 compound treatment 0.591 0.338 18.15 18.1466 1.0 3023958 ChemDiv3_003963 O=C/1N=C(S\C1=C/c2cccs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E04 compound treatment 0.306 0.0527 2.83 2.8313 1.0 3023959 ChemDiv3_003964 O=C(CSc1nnc(COc2ccccc2)o1)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E05 compound treatment 0.548 0.295 15.84 15.8359 1.0 3119249 ChemDiv3_003965 CN/1C(=N)NC(=O)\C1=C\c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E06 compound treatment 0.325 0.0717 3.85 3.8523 1.0 1871115 ChemDiv3_003966 CC(C)(CO)NC(=O)c1sc2ccccc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E07 compound treatment 0.402 0.149 7.99 7.9902 1.0 3023960 ChemDiv3_003967 C(Sc1nnc-2c(OC(Nc3ccccc32)/C=C/c4ccco4)n1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E08 compound treatment 0.325 0.0717 3.85 3.8523 1.0 3119250 ChemDiv3_003968 Cc1ccc(SCc2cc(O)nc(SCC(=O)n3c4ccccc4c5ccccc35)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E09 compound treatment 0.271 0.0177 0.95 0.9505 1.0 3023961 ChemDiv3_003969 CCSC1=N/C(=C\c2cccc(F)c2)/C(=O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E10 compound treatment 0.325 0.0717 3.85 3.8523 1.0 1156555 ChemDiv3_003970 CC1CCN(CC1)C(=O)CNS(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E11 compound treatment 0.281 0.0277 1.49 1.4879 1.0 1664682 ChemDiv3_003971 Cc1n[nH]c(C)c1N2C(=O)c3cccc4c(N)ccc(C2=O)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E12 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1473240 ChemDiv3_003972 O=C(N1CCN(Cc2cccnc2)CC1)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E13 compound treatment 0.349 0.0957 5.14 5.142 1.0 3119251 ChemDiv3_003973 CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc4OCOc4c3)c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E14 compound treatment 0.292 0.0387 2.08 2.079 1.0 1668191 ChemDiv3_003974 CCOc1ccc(CN(CCc2ccc3OCOc3c2)Cc4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E15 compound treatment 0.273 0.0197 1.06 1.058 1.0 1243341 ChemDiv3_003975 COc1ccc2cc(C3CC(=NN3C(=O)c4ccco4)c5ccc(OC)c(OC)c5)c(Cl)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E16 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3023962 ChemDiv3_003976 Fc1ccc(Nc2nc3ccccc3nc2Nc4ccc(F)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E17 compound treatment 0.403 0.15 8.04 8.0439 1.0 1173393 ChemDiv3_003977 CC(C)N(C(=O)Cn1c2ccccc2c3nc4ccccc4nc13)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E18 compound treatment 0.274 0.0207 1.11 1.1117 1.0 3023963 ChemDiv3_003978 OC(C#CCN1CCOCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E19 compound treatment 0.273 0.0197 1.06 1.058 1.0 3119252 ChemDiv3_003979 CCN(CC)C(=S)SC1=CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E20 compound treatment 0.543 0.29 15.57 15.5672 1.0 1158512 ChemDiv3_003980 COc1ccc2c(c1)c(=O)oc3cc(OC(C)C)ccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E21 compound treatment 0.265 0.0117 0.63 0.6281 1.0 3119253 ChemDiv3_003981 CC12CS(=O)(=O)CC2SC(=S)N1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E22 compound treatment 0.368 0.115 6.16 6.1631 1.0 1357925 ChemDiv3_003982 CN(C)C(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E23 mock treatment 0.249 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 E24 mock treatment 0.253 -3.12E-4 -0.02 -0.0168 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F01 compound treatment 0.286 0.0327 1.76 1.7566 1.0 3023964 ChemDiv3_003983 CN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C(=C(C#N)C1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F02 compound treatment 0.534 0.281 15.08 15.0836 1.0 3119382 ChemDiv3_003984 O=C(NC1=NCCS1)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F03 compound treatment 0.3 0.0467 2.51 2.5089 1.0 1627858 ChemDiv3_003985 CN(C)c1ccc2nc3C(=O)c4ccccc4C(=O)c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F04 compound treatment 0.244 -0.00931 -0.5 -0.5004 -1.0 3119383 ChemDiv3_003986 CC1=[N+]([O-])C(C)(C)[N+](=C1c2ccc(C)cc2)[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F05 compound treatment 0.407 0.154 8.26 8.2588 1.0 3119384 ChemDiv3_003987 COC(=O)c1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F06 compound treatment 0.275 0.0217 1.17 1.1654 1.0 3023965 ChemDiv3_003988 CC(C)Cc1c(O)nc(SCC(=O)NC(C)(C)C)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F07 compound treatment 0.608 0.355 19.06 19.0602 1.0 3119385 ChemDiv3_003989 Cc1ccccc1OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F08 compound treatment 0.28 0.0267 1.43 1.4341 1.0 3023966 ChemDiv3_003990 COC(=O)c1c(C)c(=O)[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F09 compound treatment 0.267 0.0137 0.74 0.7355 1.0 1509397 ChemDiv3_003991 Fc1ccc(cc1)C(=O)Nc2ncnc3sc4CCCCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F10 compound treatment 0.258 0.00469 0.25 0.2519 1.0 3023967 ChemDiv3_003992 FC(F)(F)C1(N=C(OC(=N1)c2ccccc2)N3CCCCC3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F11 compound treatment 0.398 0.145 7.78 7.7752 1.0 1229183 ChemDiv3_003993 Cc1sc2nc3c4ccccc4c(NCCO)nn3c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F12 compound treatment 0.325 0.0717 3.85 3.8523 1.0 1299234 ChemDiv3_003994 COC(=O)c1c(N)n(CCc2ccccc2)c3nc4ccccc4nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F13 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1319064 ChemDiv3_003995 Cc1ccc(Oc2nnc(c3cccs3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F14 compound treatment 0.308 0.0547 2.94 2.9388 1.0 3119386 ChemDiv3_003996 Cc1cccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F15 compound treatment 0.27 0.0167 0.9 0.8968 1.0 3023968 ChemDiv3_003997 Cn1nc(CC(=O)Nc2nc(cs2)c3ccccc3)c4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F16 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3119387 ChemDiv3_003998 COc1ccc(/N=C/c2c(O)ccc3oc4CCCCc4c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F17 compound treatment 0.26 0.00669 0.36 0.3594 1.0 1229320 ChemDiv3_003999 CCOC(=O)CN1C(=O)C2(C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OCC)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F18 compound treatment 0.326 0.0727 3.91 3.9061 1.0 1796400 ChemDiv3_004000 COc1ccc(CCn2cnc3sc4CCCCc4c3c2=N)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F19 compound treatment 0.472 0.219 11.75 11.7518 1.0 1598055 ChemDiv3_004001 Cc1cc(C(=O)CSc2nnc3cc(C)c4ccccc4n23)c(C)n1Cc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F20 compound treatment 0.492 0.239 12.83 12.8266 1.0 3024019 ChemDiv3_004002 CC(=O)N1C(=N)S/C(=C/c2cc3ccc(C)cc3nc2O)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F21 compound treatment 0.26 0.00669 0.36 0.3594 1.0 1409929 ChemDiv3_004003 Cn1nc(C(=O)O)c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F22 compound treatment 0.3 0.0467 2.51 2.5089 1.0 1387840 ChemDiv3_004004 CCOC(=O)Cc1c(C)nc(Cc2ccc(OC(C)C)cc2)nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F23 mock treatment 0.258 0.00469 0.25 0.2519 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 F24 mock treatment 0.249 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G01 compound treatment 0.262 0.00869 0.47 0.4668 1.0 3119388 ChemDiv3_004005 COC(=O)C1=CN(C=C(C1c2ccccc2)C(=O)OC)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G02 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3024021 ChemDiv3_004006 Cc1cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c(C)n1c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G03 compound treatment 0.252 -0.00131 -0.07 -0.0705 -1.0 3119389 ChemDiv3_004007 c1ccc2sc(nc2c1)c3cccc(n3)c4nc5ccccc5s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G04 compound treatment 0.536 0.283 15.19 15.191 1.0 3119390 ChemDiv3_004008 COc1ccc(Cc2nnc(SCC(=O)Nc3ccc(OC)cc3)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G05 compound treatment 0.575 0.322 17.29 17.2868 1.0 3024022 ChemDiv3_004009 COc1ccc(/C=C/C=N/n2c(SC)nnc2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G06 compound treatment 0.525 0.272 14.6 14.5999 1.0 1871125 ChemDiv3_004010 Cc1c(C)c2ccccc2n1C(=O)CSc3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G07 compound treatment 0.288 0.0347 1.86 1.864 1.0 1673764 ChemDiv3_004011 CC(=O)N1C(Oc2nc(SCC=C)nnc2-c3ccccc13)c4ccc(o4)c5ccc(F)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G08 compound treatment 0.461 0.208 11.16 11.1607 1.0 3119391 ChemDiv3_004012 COc1ccc(NC(=O)C2CC(=O)N=C(Nc3ccccc3)S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G09 compound treatment 0.262 0.00869 0.47 0.4668 1.0 1613829 ChemDiv3_004013 CCSc1nnc(c(O)n1)c2ccccc2NC(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G10 compound treatment 0.25 -0.00331 -0.18 -0.178 -1.0 1558726 ChemDiv3_004014 CC(C)(C)NC(=O)N1c2ccccc2Sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G11 compound treatment 0.254 6.88E-4 0.04 0.0369 1.0 3119392 ChemDiv3_004015 Cc1nn(C)c(C)c1NC(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G12 compound treatment 0.272 0.0187 1.0 1.0042 1.0 1465103 ChemDiv3_004016 CCc1ccc(CN2CCN(Cc3cccc(OC)c3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G13 compound treatment 0.331 0.0777 4.17 4.1748 1.0 3119393 ChemDiv3_004017 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(F)cc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G14 compound treatment 0.261 0.00769 0.41 0.4131 1.0 1303056 ChemDiv3_004018 CC(C)(C)NC1=C(N(CC(=O)c2ccccc2)S(=O)(=O)c3ccccc13)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G15 compound treatment 0.256 0.00269 0.14 0.1444 1.0 1692964 ChemDiv3_004019 CCC(=O)N1N=C(CC1c2cc3cc(OC)ccc3nc2Cl)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G16 compound treatment 0.296 0.0427 2.29 2.2939 1.0 1699942 ChemDiv3_004020 Brc1ccc(cc1)C2NC(=O)c3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G17 compound treatment 0.26 0.00669 0.36 0.3594 1.0 3024023 ChemDiv3_004021 CC(=O)OC1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G18 compound treatment 0.351 0.0977 5.25 5.2495 1.0 3119394 ChemDiv3_004022 CCCc1n[nH]c2OC(=C(C#N)C(CCc3ccccc3)c12)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G19 compound treatment 0.263 0.00969 0.52 0.5206 1.0 3024024 ChemDiv3_004023 CC1(CCS(=O)(=O)C1)NC(=S)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G20 compound treatment 0.471 0.218 11.7 11.6981 1.0 1713974 ChemDiv3_004024 Oc1cc(OCC(=O)c2ccccc2)cc3oc(cc(=O)c13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G21 compound treatment 0.279 0.0257 1.38 1.3804 1.0 1338699 ChemDiv3_004025 CCCCN(C1CCS(=O)(=O)C1)C(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G22 compound treatment 0.326 0.0727 3.91 3.9061 1.0 1306939 ChemDiv3_004026 Cc1c(OC(=O)c2ccco2)ccc3c4CCCc4c(=O)oc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G23 mock treatment 0.259 0.00569 0.31 0.3056 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 G24 mock treatment 0.257 0.00369 0.2 0.1982 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H01 compound treatment 0.437 0.184 9.87 9.871 1.0 3119395 ChemDiv3_004027 CC(C)N1C(=O)S/C(=C/c2ccc(Sc3nc4ccccc4[nH]3)o2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H02 compound treatment 0.274 0.0207 1.11 1.1117 1.0 3024025 ChemDiv3_004028 Cc1c(c2ccco2)[n+]([O-])c(c(C)[n+]1[O-])c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H03 compound treatment 0.323 0.0697 3.74 3.7449 1.0 3119396 ChemDiv3_004029 C/C(=N\O)/CCc1oc2ccccc2c1c3ccc(C)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H04 compound treatment 0.274 0.0207 1.11 1.1117 1.0 3024026 ChemDiv3_004030 CC1N(O)C(C)(C)[N+](=C1c2ccccc2)[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H05 compound treatment 0.273 0.0197 1.06 1.058 1.0 3024027 ChemDiv3_004031 CC(=O)N/C(=C\c1cccs1)/C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H06 compound treatment 0.284 0.0307 1.65 1.6491 1.0 3119397 ChemDiv3_004032 CCSc1nc(O)c(C(C)CC)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H07 compound treatment 0.451 0.198 10.62 10.6233 1.0 1130593 ChemDiv3_004033 O=C(Cc1ccccc1)Nc2cccc(c2)S(=O)(=O)c3cccc(NC(=O)Cc4ccccc4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H08 compound treatment 0.405 0.152 8.15 8.1514 1.0 3024028 ChemDiv3_004034 CCOC(=O)c1nn(c(C#N)c1NC(=O)c2nn(CC)cc2Br)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H09 compound treatment 0.414 0.161 8.64 8.635 1.0 1423488 ChemDiv3_004035 COc1cc2c(cc1NP(=O)(C)Oc3ccccc3)oc4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H10 compound treatment 0.277 0.0237 1.27 1.2729 1.0 3024029 ChemDiv3_004036 COc1ccc(Cl)cc1NC2=NCC(C)S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H11 compound treatment 0.327 0.0737 3.96 3.9598 1.0 1247540 ChemDiv3_004037 CC1CCN(CC1)c2nn3c(=O)c4c(C)c(C)sc4nc3c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H12 compound treatment 0.272 0.0187 1.0 1.0042 1.0 1685422 ChemDiv3_004038 CCOC(=O)c1c(N)n(C2CCCCC2)c3nc4ccccc4nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H13 compound treatment 0.416 0.163 8.74 8.7425 1.0 1241398 ChemDiv3_004039 C1CCCN(CC1)c2nnc(c3cccs3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H14 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3119548 ChemDiv3_004040 CCc1ccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H15 compound treatment 0.417 0.164 8.8 8.7962 1.0 3024030 ChemDiv3_004041 O=C(Oc1ccc(cc1)N(Cc2cccs2)C3=NS(=O)(=O)c4ccccc34)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H16 compound treatment 0.263 0.00969 0.52 0.5206 1.0 3119549 ChemDiv3_004042 Oc1ccc2oc3CCCCc3c2c1/C=N/N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H17 compound treatment 0.269 0.0157 0.84 0.843 1.0 1705908 ChemDiv3_004043 CCOC(=O)CN1C(=O)C2(C(=C(N)Oc3[nH]nc(C)c32)C#N)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H18 compound treatment 0.442 0.189 10.14 10.1397 1.0 3024031 ChemDiv3_004044 COc1ccc(CCn2cnc3oc(c(c4ccccc4)c3c2=N)c5ccccc5)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H19 compound treatment 0.256 0.00269 0.14 0.1444 1.0 3119550 ChemDiv3_004045 Cc1nc(SC2CCCCN(C(=O)c3ccc(Cl)cc3)C2=O)c4c5CCCCc5sc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H20 compound treatment 0.278 0.0247 1.33 1.3267 1.0 3442340 ChemDiv3_004046 CC(C)CC(Nc1ncnc2sc3CCCc3c12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H21 compound treatment 0.306 0.0527 2.83 2.8313 1.0 3024084 ChemDiv3_004047 COC(=O)/C=c/1\sc2ncnn2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H22 compound treatment 0.269 0.0157 0.84 0.843 1.0 1470170 ChemDiv3_004048 Nc1cc(=O)nc(SCC(=O)NCc2ccccc2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H23 mock treatment 0.242 -0.0113 -0.61 -0.6079 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 H24 mock treatment 0.251 -0.00231 -0.12 -0.1243 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I01 compound treatment 0.246 -0.00731 -0.39 -0.393 -1.0 3024085 ChemDiv3_004049 Cc1[n+](CC=C)n(C)c2cc(Cl)c(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I02 compound treatment 0.281 0.0277 1.49 1.4879 1.0 3119551 ChemDiv3_004050 COCCn1c(C)cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I03 compound treatment 0.299 0.0457 2.46 2.4552 1.0 1185967 ChemDiv3_004051 CCSc1nnc-2c(OC(Nc3ccccc32)c4cc5OCOc5cc4Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I04 compound treatment 0.541 0.288 15.46 15.4597 1.0 3119552 ChemDiv3_004052 COc1ccc(Cl)c(NC2=NC(=O)/C(=C\c3cccnc3)/S2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I05 compound treatment 0.274 0.0207 1.11 1.1117 1.0 1528287 ChemDiv3_004053 CSc1nnc-2c(OC(C)N(C(=O)C)c3ccccc32)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I06 compound treatment 0.464 0.211 11.32 11.3219 1.0 1788578 ChemDiv3_004054 O=C(CSc1nnc(o1)c2ccccc2)N3c4ccccc4CCc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I07 compound treatment 0.276 0.0227 1.22 1.2192 1.0 3024086 ChemDiv3_004055 COC(=O)C1=C(C)NC(=S)NC1c2cc3OCOc3cc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I08 compound treatment 0.257 0.00369 0.2 0.1982 1.0 3119553 ChemDiv3_004056 FC(F)(F)c1cccc(c1)n2c(=O)oc3ccc(Cl)cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I09 compound treatment 0.44 0.187 10.03 10.0322 1.0 3119554 ChemDiv3_004057 CCc1ccc2NC(=O)/C(=C/3\S\C(=N/c4cccc(Cl)c4C)\NC3=O)/c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I10 compound treatment 0.303 0.0497 2.67 2.6701 1.0 1437793 ChemDiv3_004058 O=C(NCCc1ccccc1)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I11 compound treatment 0.316 0.0627 3.37 3.3687 1.0 3119555 ChemDiv3_004059 COC(=O)c1cc2c(C)nn(c3ccccc3)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I12 compound treatment 0.271 0.0177 0.95 0.9505 1.0 1679546 ChemDiv3_004060 CCc1ccc(CN2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I13 compound treatment 0.338 0.0847 4.55 4.5509 1.0 3119556 ChemDiv3_004061 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(OC)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I14 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3024087 ChemDiv3_004062 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I15 compound treatment 0.305 0.0517 2.78 2.7776 1.0 1737307 ChemDiv3_004063 O=C(N1N=C(CC1c2ccc3nccnc3c2)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I16 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3024088 ChemDiv3_004064 NC(=N)SCC1CN=C(S1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I17 compound treatment 0.265 0.0117 0.63 0.6281 1.0 1449842 ChemDiv3_004065 CNC(=S)NC1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I18 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3119557 ChemDiv3_004066 CCCOc1ccc(cc1OCC)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I19 compound treatment 0.263 0.00969 0.52 0.5206 1.0 3024089 ChemDiv3_004067 CCCC(NC1CCS(=O)(=O)C1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I20 compound treatment 0.452 0.199 10.68 10.6771 1.0 1874878 ChemDiv3_004068 COc1ccc2c(c1)c(=O)oc3c(C)c(OC(C(=O)O)c4ccccc4)ccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I21 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1557945 ChemDiv3_004069 CCc1ccccc1NC(=O)CC2CS(=O)(=O)CC2CC(=O)Nc3ccccc3CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I22 compound treatment 0.282 0.0287 1.54 1.5416 1.0 3024090 ChemDiv3_004070 Cc1cc(OC(=O)c2cccs2)c3c4CCCc4c(=O)oc3c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I23 mock treatment 0.255 0.00169 0.09 0.0907 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 I24 mock treatment 0.263 0.00969 0.52 0.5206 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J01 compound treatment 0.371 0.118 6.32 6.3243 1.0 3024091 ChemDiv3_004071 CC(C)N1C(=O)S/C(=C/c2cc(C)n(c2C)c3ccncc3)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J02 compound treatment 0.28 0.0267 1.43 1.4341 1.0 3119558 ChemDiv3_004072 CC(=O)OC1CCC(OC(=O)C)c2c1[n+]([O-])c(C)c(C)[n+]2[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J03 compound treatment 0.354 0.101 5.41 5.4107 1.0 3024092 ChemDiv3_004073 S=c1cc(oc(c1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J04 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3119559 ChemDiv3_004074 Cc1c(c2ccccc2)[n+]([O-])c(c(C)[n+]1[O-])c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J05 compound treatment 0.486 0.233 12.5 12.5041 1.0 1128591 ChemDiv3_004075 COc1ccc(CC(=O)Nc2cccc(c2)c3nc4cc5ccccc5cc4[nH]3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J06 compound treatment 0.29 0.0367 1.97 1.9715 1.0 1255030 ChemDiv3_004076 COc1ccc(cc1OC)C2C(c3cc(OC)c(OC)cc3C2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J07 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3119560 ChemDiv3_004077 O=C(Nc1cccc(c1)c2nc3ccccc3c(=O)o2)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J08 compound treatment 0.275 0.0217 1.17 1.1654 1.0 3024093 ChemDiv3_004078 CCOC(=O)c1nn(c(C(=O)OCC)c1NC(=O)C2CCCCC2)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J09 compound treatment 0.269 0.0157 0.84 0.843 1.0 1215988 ChemDiv3_004079 OC(=O)c1c2CC(CCc2nc3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J10 compound treatment 0.302 0.0487 2.62 2.6164 1.0 3119561 ChemDiv3_004080 CC1CN=C(S1)N(C(=O)Nc2ccccc2)c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J11 compound treatment 0.264 0.0107 0.57 0.5743 1.0 1549011 ChemDiv3_004081 Cc1ccc(cc1)c2nn3c(=O)c4ccccc4nc3c5ccccc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J12 compound treatment 0.338 0.0847 4.55 4.5509 1.0 1317257 ChemDiv3_004082 CCc1ccc(cc1)n2c(N)c(C(=O)OC)c3nc4ccccc4nc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J13 compound treatment 0.378 0.125 6.7 6.7004 1.0 3024094 ChemDiv3_004083 O=C(CSc1ncnc2sc(cc12)c3ccccc3)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J14 compound treatment 0.259 0.00569 0.31 0.3056 1.0 3119562 ChemDiv3_004084 FC(F)(F)c1cccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J15 compound treatment 0.287 0.0337 1.81 1.8103 1.0 1305983 ChemDiv3_004085 CCCN1CC=C2C(C1)C3(C(=O)Nc4ccccc43)C(C#N)(C#N)C(=C2C#N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J16 compound treatment 0.268 0.0147 0.79 0.7893 1.0 1458619 ChemDiv3_004086 CC(C)(C)c1nc2scc(c3ccccc3)c2c(=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J17 compound treatment 0.269 0.0157 0.84 0.843 1.0 1274153 ChemDiv3_004087 CCOC(=O)C1=C(N)Oc2c(c(=O)oc3ccccc23)C41C(=O)N(CC(=O)OC)c5ccccc54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J18 compound treatment 0.411 0.158 8.47 8.4738 1.0 1393431 ChemDiv3_004088 CCn1c(=O)c2c(-c3ccccc3CC42CCCCC4)n5c(SCC(=O)N)nnc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J19 compound treatment 0.239 -0.0143 -0.77 -0.7691 -1.0 3119696 ChemDiv3_004089 CCN(CC)C(=O)O[n+]1cccc(CC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J20 compound treatment 0.293 0.0397 2.13 2.1327 1.0 3119697 ChemDiv3_004090 C=CCN1C(=C(OC(=O)c2ccccc2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J21 compound treatment 0.255 0.00169 0.09 0.0907 1.0 1423420 ChemDiv3_004091 Cc1cc(C)n(n1)c2nnc(C)n2NC(=S)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J22 compound treatment 0.269 0.0157 0.84 0.843 1.0 3119698 ChemDiv3_004092 COC(=O)/C=C/1\N(C(=NC1=O)Nc2nc(C)cc(C)n2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J23 mock treatment 0.247 -0.00631 -0.34 -0.3392 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 J24 mock treatment 0.248 -0.00531 -0.29 -0.2855 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K01 compound treatment 0.291 0.0377 2.03 2.0252 1.0 3023297 ChemDiv3_004093 Oc1cc(C2C(=O)c3ccccc3C2=O)c4ccc5ccccc5c4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K02 compound treatment 0.271 0.0177 0.95 0.9505 1.0 3119699 ChemDiv3_004094 COCCn1c(C)cc(C=C2C(=O)N(C)C(=S)N(C)C2=O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K03 compound treatment 0.277 0.0237 1.27 1.2729 1.0 1169810 ChemDiv3_004095 CSc1nnc-2c(OC(Nc3ccccc32)c4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K04 compound treatment 0.599 0.346 18.58 18.5765 1.0 3119700 ChemDiv3_004096 OC(=O)c1ccc(cc1)c2ccc(/C=C\3/SC(=NC3=O)Nc4cccc(c4)C(=O)O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K05 compound treatment 0.534 0.281 15.08 15.0836 1.0 3119701 ChemDiv3_004097 CC/1=NN(C(=O)\C1=C/Nc2cc(C)ccn2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K06 compound treatment 0.269 0.0157 0.84 0.843 1.0 1871177 ChemDiv3_004098 COc1ccc(Nc2nc(N)nc(CN3CCCCC3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K07 compound treatment 0.564 0.311 16.7 16.6957 1.0 3119702 ChemDiv3_004099 CN/1C(=N)NC(=O)\C1=C\c2ccc(C)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K08 compound treatment 0.239 -0.0143 -0.77 -0.7691 -1.0 3023298 ChemDiv3_004100 COc1ccc(C=C2C(=O)OC3(CCCCC3)OC2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K09 compound treatment 0.323 0.0697 3.74 3.7449 1.0 3119703 ChemDiv3_004101 CCOc1cc(/C=C/2\C(=O)Nc3ccc(Br)cc23)ccc1OCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K10 compound treatment 0.285 0.0317 1.7 1.7028 1.0 1400389 ChemDiv3_004102 CCOC(=O)C1CCN(CC1)C(=O)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K11 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1679244 ChemDiv3_004103 Cc1ccc(Nc2nc(C)cc(C)c2C(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K12 compound treatment 0.271 0.0177 0.95 0.9505 1.0 1721188 ChemDiv3_004104 CCCS(=O)(=O)N1CCN(CC1)C2CCN(CC2)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K13 compound treatment 0.312 0.0587 3.15 3.1537 1.0 1612458 ChemDiv3_004105 CCn1c2ccccc2c3cc(NS(=O)(=O)c4ccccc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K14 compound treatment 0.256 0.00269 0.14 0.1444 1.0 1300482 ChemDiv3_004106 CN1C(=C(N2CCOCC2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K15 compound treatment 0.288 0.0347 1.86 1.864 1.0 3023329 ChemDiv3_004107 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K16 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3119704 ChemDiv3_004108 NC1(N)OC(CN2C(=O)c3ccccc3C2=O)CS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K17 compound treatment 0.26 0.00669 0.36 0.3594 1.0 1697884 ChemDiv3_004109 CCOC(=O)NC1CS(=O)(=O)C=C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K18 compound treatment 0.264 0.0107 0.57 0.5743 1.0 3119705 ChemDiv3_004110 CCN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4ccc(OC)cc4)C(=O)CC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K19 compound treatment 0.262 0.00869 0.47 0.4668 1.0 1179086 ChemDiv3_004111 O=S1(=O)CCC(C1)NC(=S)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K20 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3119706 ChemDiv3_004112 CCCN1Cc2cccc(C(=O)N)c2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K21 compound treatment 0.275 0.0217 1.17 1.1654 1.0 1541504 ChemDiv3_004113 CC(C)NC(=S)SC1CS(=O)(=O)C=C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K22 compound treatment 0.343 0.0897 4.82 4.8196 1.0 1280043 ChemDiv3_004114 Cc1cc(=O)oc2cc(OCc3cccc(F)c3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K23 mock treatment 0.26 0.00669 0.36 0.3594 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 K24 mock treatment 0.262 0.00869 0.47 0.4668 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L01 compound treatment 0.29 0.0367 1.97 1.9715 1.0 3119707 ChemDiv3_004115 COCCN1C(=O)N(C(=O)/C(=C\c2cn(CC(=O)OC)c3ccccc23)/C1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L02 compound treatment 0.457 0.204 10.95 10.9457 1.0 3023337 ChemDiv3_004116 CC1=[N+]([O-])C(C)(C)C(=[N+]1[O-])c2ccc(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L03 compound treatment 0.316 0.0627 3.37 3.3687 1.0 3119708 ChemDiv3_004117 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L04 compound treatment 0.264 0.0107 0.57 0.5743 1.0 3023341 ChemDiv3_004118 [O-][n+]1cc(c2ccccc2)[n+]([O-])c3CCCCc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L05 compound treatment 0.353 0.0997 5.36 5.357 1.0 3023342 ChemDiv3_004119 CC(C)C(=O)Nc1cccc(c1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L06 compound treatment 0.357 0.104 5.57 5.5719 1.0 3119709 ChemDiv3_004120 CCc1ccc(OCCCn2cc(/C=C\3/C(=N)N4C=CSC4=NC3=O)c5ccccc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L07 compound treatment 0.445 0.192 10.3 10.3009 1.0 3023344 ChemDiv3_004121 CCSc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L08 compound treatment 0.278 0.0247 1.33 1.3267 1.0 1713113 ChemDiv3_004122 O=S1(=O)C=C(SCCN2CCOCC2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L09 compound treatment 0.488 0.235 12.61 12.6116 1.0 3023346 ChemDiv3_004123 CN(C)c1oc(nc1C#N)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L10 compound treatment 0.302 0.0487 2.62 2.6164 1.0 3119710 ChemDiv3_004124 CCC1(COC(NC(=O)c2ccc(Cl)cc2Cl)(C(F)(F)F)C(F)(F)F)COC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L11 compound treatment 0.345 0.0917 4.93 4.9271 1.0 1380020 ChemDiv3_004125 CCC1CCc2c(C1)sc3ncnc(N4CCOCC4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L12 compound treatment 0.403 0.15 8.04 8.0439 1.0 1709855 ChemDiv3_004126 CCOc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L13 compound treatment 0.262 0.00869 0.47 0.4668 1.0 1688543 ChemDiv3_004127 Cc1cc(C)c(C)c(c1C)S(=O)(=O)N2CCN(CC2)c3ncnc4sc5CCCCc5c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L14 compound treatment 0.279 0.0257 1.38 1.3804 1.0 1554741 ChemDiv3_004128 COc1ccc2n(CCc3ccc(OC)c(OC)c3)c(C)c(C(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L15 compound treatment 0.258 0.00469 0.25 0.2519 1.0 1579821 ChemDiv3_004129 COC(=O)CC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L16 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3119711 ChemDiv3_004130 O/N=C/c1c(O)c(Br)cc2oc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L17 compound treatment 0.274 0.0207 1.11 1.1117 1.0 1421908 ChemDiv3_004131 O=c1n(CN2CCCCC2)nnc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L18 compound treatment 0.381 0.128 6.86 6.8617 1.0 1535030 ChemDiv3_004132 COc1ccc(cc1)C(=O)n2nc3CC(C)(C)OCc3c2c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L19 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3119712 ChemDiv3_004133 Cc1ccc(cc1)S(=O)(=O)N/2C(=O)C(C)(C)S\C2=N/CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L20 compound treatment 0.261 0.00769 0.41 0.4131 1.0 1346941 ChemDiv3_004134 CN1CCN(Cc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L21 compound treatment 0.471 0.218 11.7 11.6981 1.0 3119713 ChemDiv3_004135 Cc1nnc(SCc2cccc(c2)C(=O)c3ccccc3)nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L22 compound treatment 0.258 0.00469 0.25 0.2519 1.0 3119714 ChemDiv3_004136 CC1CCN(CC1)/C(=N\S(=O)(=O)c2ccc(Br)cc2)/Nc3nc(C)cc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L23 mock treatment 0.277 0.0237 1.27 1.2729 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 L24 mock treatment 0.249 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M01 compound treatment 0.434 0.181 9.71 9.7098 1.0 3119869 ChemDiv3_004137 CCc1cc(C)cc(OCCn2cc(C=C3C(=O)NC(=O)NC3=O)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M02 compound treatment 0.267 0.0137 0.74 0.7355 1.0 3023448 ChemDiv3_004138 CN1C(=O)C(=Cc2cn(CC=C)c3ccccc23)C(=O)N(C)C1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M03 compound treatment 0.27 0.0167 0.9 0.8968 1.0 3023450 ChemDiv3_004139 CCc1cccc2c1NC(=O)C32OCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M04 compound treatment 0.582 0.329 17.66 17.663 1.0 1912757 ChemDiv3_004140 Cc1cc2/C(=C/c3ccco3)/OC(=O)c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M05 compound treatment 0.263 0.00969 0.52 0.5206 1.0 3119870 ChemDiv3_004141 CCSC1=N/C(=C\c2ccc(cc2)C(=O)O)/C(=O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M06 compound treatment 0.379 0.126 6.75 6.7542 1.0 3023453 ChemDiv3_004142 O=C(COc1ccccc1)N2CCN=C2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M07 compound treatment 0.267 0.0137 0.74 0.7355 1.0 1181595 ChemDiv3_004143 CCC(=O)N1C(Oc2nc(SC)nnc2-c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M08 compound treatment 0.374 0.121 6.49 6.4855 1.0 1618375 ChemDiv3_004144 S=C1NC(C2=C(N1)c3ccccc3CC2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M09 compound treatment 0.261 0.00769 0.41 0.4131 1.0 3023457 ChemDiv3_004145 CCCCN1C(=O)/C(=C/2\S/C(=N\c3ccc(Cl)cc3)/N(C)C2=O)/c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M10 compound treatment 0.286 0.0327 1.76 1.7566 1.0 3119871 ChemDiv3_004146 O=C(NCCCc1ccccc1)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M11 compound treatment 0.358 0.105 5.63 5.6257 1.0 1406185 ChemDiv3_004147 Cc1cc(C)c2c(N=NN3CCCCCC3)n[nH]c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M12 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3119872 ChemDiv3_004148 Cc1cc(Br)ccc1NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M13 compound treatment 0.26 0.00669 0.36 0.3594 1.0 1438334 ChemDiv3_004149 Brc1ccc2oc(=O)c(cc2c1)C(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M14 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3023462 ChemDiv3_004150 CN1C(=C(Nc2ccccc2C)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M15 compound treatment 0.325 0.0717 3.85 3.8523 1.0 1567678 ChemDiv3_004151 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M16 compound treatment 0.275 0.0217 1.17 1.1654 1.0 3023506 ChemDiv3_004152 OC(=O)CP(=S)(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M17 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1339249 ChemDiv3_004153 CCSC(=S)NC1CCS(=O)(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M18 compound treatment 0.275 0.0217 1.17 1.1654 1.0 3119873 ChemDiv3_004154 CCN1C2=C(C(C3=C1CCCC3=O)c4cccc(O)c4)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M19 compound treatment 0.257 0.00369 0.2 0.1982 1.0 1468946 ChemDiv3_004155 CN(C1CCS(=O)(=O)C1)C(=S)SC2CS(=O)(=O)C=C2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M20 compound treatment 0.347 0.0937 5.03 5.0346 1.0 1541732 ChemDiv3_004156 COC(=O)c1ccc(COc2ccc3c(cc(=O)oc3c2C)c4ccccc4)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M21 compound treatment 0.255 0.00169 0.09 0.0907 1.0 1306134 ChemDiv3_004157 CN(C1CCCCC1)S(=O)(=O)C2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M22 compound treatment 0.561 0.308 16.53 16.5345 1.0 3119874 ChemDiv3_004158 CC1CN(CC(C)O1)C2=NC(=O)/C(=C/c3ccccc3)/S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M23 mock treatment 0.249 -0.00431 -0.23 -0.2317 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 M24 mock treatment 0.248 -0.00531 -0.29 -0.2855 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N01 compound treatment 0.367 0.114 6.11 6.1093 1.0 3023511 ChemDiv3_004159 O=C1S/C(=C\c2ccc(o2)N3CCOCC3)/C(=O)N1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N02 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3119875 ChemDiv3_004160 CC1=[N+]([O-])C(C)(C)C(=[N+]1[O-])c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N03 compound treatment 0.277 0.0237 1.27 1.2729 1.0 3023512 ChemDiv3_004161 C1CCC2=C(C1)SC3=C(CCCC3)C2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N04 compound treatment 0.567 0.314 16.86 16.8569 1.0 1863423 ChemDiv3_004162 CSc1cccc(NC(=O)c2cc3c(ccc4ccccc34)o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N05 compound treatment 0.273 0.0197 1.06 1.058 1.0 3023514 ChemDiv3_004163 O=C(ON1C(=O)c2ccccc2C1=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N06 compound treatment 0.29 0.0367 1.97 1.9715 1.0 1713635 ChemDiv3_004164 COC(=O)C1=C(C)Nc2c(C1c3cccc(OCc4ccccc4)c3)c(=O)n(C)c(=O)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N07 compound treatment 0.271 0.0177 0.95 0.9505 1.0 3023519 ChemDiv3_004165 CCCCS(=O)(=O)N=C1NCN(CCO)CN1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N08 compound treatment 0.262 0.00869 0.47 0.4668 1.0 3119876 ChemDiv3_004166 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N09 compound treatment 0.28 0.0267 1.43 1.4341 1.0 3119877 ChemDiv3_004167 CCOC(=O)c1c(NC(=O)CC2S/C(=N\CC)/N(CC)C2=O)sc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N10 compound treatment 0.247 -0.00631 -0.34 -0.3392 -1.0 3023583 ChemDiv3_004168 COc1ccc(CNC(=N)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N11 compound treatment 0.477 0.224 12.02 12.0205 1.0 1550858 ChemDiv3_004169 CC1CCN(CC1)c2nnc(c3cccs3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N12 compound treatment 0.278 0.0247 1.33 1.3267 1.0 1484112 ChemDiv3_004170 O=S(=O)(Nc1nc2ccccc2nc1NCCC3=CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N13 compound treatment 0.265 0.0117 0.63 0.6281 1.0 1570344 ChemDiv3_004171 CCc1nc(n2nnc3cc(C)c(C)cc23)c4c5CCCCc5sc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N14 compound treatment 0.299 0.0457 2.46 2.4552 1.0 1352096 ChemDiv3_004172 CCOC(=O)c1c(C)n(C(C)C)c2ccc(OC(=O)c3ccccc3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N15 compound treatment 0.257 0.00369 0.2 0.1982 1.0 1652261 ChemDiv3_004173 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C32C(=O)N(CO)c4ccccc43)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N16 compound treatment 0.252 -0.00131 -0.07 -0.0705 -1.0 3023589 ChemDiv3_004174 CC(C)(C)c1cc2oc3CCCCc3c2c(/C=N/Cc4ccncc4)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N17 compound treatment 0.267 0.0137 0.74 0.7355 1.0 1176412 ChemDiv3_004175 Cc1onc(c1C(=O)NC(=S)NCc2ccco2)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N18 compound treatment 0.257 0.00369 0.2 0.1982 1.0 1286690 ChemDiv3_004176 CC1(C)CC(CC(=O)N2CCOCC2)(CCO1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N19 compound treatment 0.335 0.0817 4.39 4.3897 1.0 1350975 ChemDiv3_004177 Cc1nn(C(=O)c2cccnc2)c(c1Sc3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N20 compound treatment 0.268 0.0147 0.79 0.7893 1.0 3119878 ChemDiv3_004178 CCCN(CCC)CN1CC(Cn2c3ccccc3c4ccccc24)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N21 compound treatment 0.255 0.00169 0.09 0.0907 1.0 1867988 ChemDiv3_004179 CC1CC(c2ccccc2)c3cc(C)ccc3N1S(=O)(=O)c4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N22 compound treatment 0.383 0.13 6.97 6.9691 1.0 3119879 ChemDiv3_004180 Clc1ccc(cc1)C(=O)NC(=N)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N23 mock treatment 0.253 -3.12E-4 -0.02 -0.0168 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 N24 mock treatment 0.239 -0.0143 -0.77 -0.7691 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O01 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3023594 ChemDiv3_004181 CSc1nnc(c(O)n1)c2ccccc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O02 compound treatment 0.334 0.0807 4.34 4.336 1.0 3119880 ChemDiv3_004182 NC(=O)COc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O03 compound treatment 0.368 0.115 6.16 6.1631 1.0 3023659 ChemDiv3_004183 CCc1ccc2NC(=O)/C(=C/3\NC(=S)NC3=O)/c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O04 compound treatment 0.266 0.0127 0.68 0.6818 1.0 1537162 ChemDiv3_004184 COCc1cc(C)nc2sc(C(=O)N)c(N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O05 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3023662 ChemDiv3_004185 COc1cccc(/C=C/2\N=C(SC)SC2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O06 compound treatment 0.414 0.161 8.64 8.635 1.0 3119881 ChemDiv3_004186 COc1cc(OC)cc(c1)C(=O)N2CCN=C2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O07 compound treatment 0.556 0.303 16.27 16.2658 1.0 3023663 ChemDiv3_004187 CCN(CC)c1ccc(/C=C/2\N(C)C(=N)NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O08 compound treatment 0.332 0.0787 4.23 4.2285 1.0 3119882 ChemDiv3_004188 CC(O)CN1C(=O)/C(=C/c2ccc(o2)c3ccc(Br)cc3)/C(=C(C#N)C1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O09 compound treatment 0.251 -0.00231 -0.12 -0.1243 -1.0 3023665 ChemDiv3_004189 CSC1=N/C(=C\c2ccc(Br)cc2)/C(=O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O10 compound treatment 0.246 -0.00731 -0.39 -0.393 -1.0 1520777 ChemDiv3_004190 CN1C(=O)C(C2CC1(C)Oc3ccccc23)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O11 compound treatment 0.296 0.0427 2.29 2.2939 1.0 1527053 ChemDiv3_004191 O=C(CN1CC(=O)Oc2ccccc12)OCC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O12 compound treatment 0.225 -0.0283 -1.52 -1.5215 -1.0 3120033 ChemDiv3_004192 CCn1c2ccccc2c3cc(CNCCc4ccc(Cl)cc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O13 compound treatment 0.274 0.0207 1.11 1.1117 1.0 1472912 ChemDiv3_004193 O=C(NC1(CCCCC1)C#N)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O14 compound treatment 0.266 0.0127 0.68 0.6818 1.0 3120034 ChemDiv3_004194 CCCN(CCC)C1=C(N(C)S(=O)(=O)c2ccccc12)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O15 compound treatment 0.337 0.0837 4.5 4.4972 1.0 3120035 ChemDiv3_004195 CS(=O)(=O)N1N=C(CC1c2cc3ccccc3nc2Cl)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O16 compound treatment 0.305 0.0517 2.78 2.7776 1.0 1484690 ChemDiv3_004196 OC(=O)CCNc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O17 compound treatment 0.258 0.00469 0.25 0.2519 1.0 3120036 ChemDiv3_004197 C=CCN1[C@H]2CS(=O)(=O)C[C@H]2NC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O18 compound treatment 0.278 0.0247 1.33 1.3267 1.0 1564957 ChemDiv3_004198 CCOc1ccc(cc1)C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O19 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3023723 ChemDiv3_004199 CC1=CS(=O)(=O)CC1Sc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O20 compound treatment 0.515 0.262 14.06 14.0625 1.0 1479636 ChemDiv3_004200 Cc1oc(cc1COc2ccc3c4CCCCc4c(=O)oc3c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O21 compound treatment 0.403 0.15 8.04 8.0439 1.0 3023725 ChemDiv3_004201 Cc1nc2sc3CCCCc3c2c4nnc(SCC(=O)c5ccccc5)n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O22 compound treatment 0.269 0.0157 0.84 0.843 1.0 3120037 ChemDiv3_004202 CC1CCC2(CC1)NN(C(=S)N2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O23 mock treatment 0.258 0.00469 0.25 0.2519 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 O24 mock treatment 0.258 0.00469 0.25 0.2519 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P01 compound treatment 0.275 0.0217 1.17 1.1654 1.0 3120038 ChemDiv3_004203 COCCN1C(=O)N(C(=O)/C(=C\c2cc(C)n(c2C)c3ccncc3)/C1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P02 compound treatment 0.289 0.0357 1.92 1.9178 1.0 3023728 ChemDiv3_004204 CCc1c(C)[n+]([O-])c2CCCCCc2[n+]1[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P03 compound treatment 0.373 0.12 6.43 6.4318 1.0 3023729 ChemDiv3_004205 COC(=O)c1ccc(OCC(O)Cn2c(C)[n+](C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P04 compound treatment 0.331 0.0777 4.17 4.1748 1.0 3120039 ChemDiv3_004206 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCN(CC3)C(=O)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P05 compound treatment 0.259 0.00569 0.31 0.3056 1.0 3023733 ChemDiv3_004207 O=C(ON1C(=O)c2ccccc2C1=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P06 compound treatment 0.245 -0.00831 -0.45 -0.4467 -1.0 1192417 ChemDiv3_004208 COc1cc(cc(OC)c1OC)C2C3=C(CCCC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P07 compound treatment 0.412 0.159 8.53 8.5275 1.0 3120040 ChemDiv3_004209 CC(=O)Nc1ccc(cc1)S(=O)(=O)N=C2NCN(CCOC(=O)c3ccccc3)CN2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P08 compound treatment 0.287 0.0337 1.81 1.8103 1.0 3023735 ChemDiv3_004210 COC(=O)c1c(C)nn(c1NC(=O)C(C)Oc2ccc(Cl)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P09 compound treatment 0.264 0.0107 0.57 0.5743 1.0 1521251 ChemDiv3_004211 Cc1cc2nnn(c3nc(C)nc4sc5CCCCc5c34)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P10 compound treatment 0.279 0.0257 1.38 1.3804 1.0 3023737 ChemDiv3_004212 CSc1nc(C)cc(NC(=O)N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P11 compound treatment 0.264 0.0107 0.57 0.5743 1.0 1165643 ChemDiv3_004213 CC(C)(C)c1ccc(cc1)c2cc3ccccn3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P12 compound treatment 0.245 -0.00831 -0.45 -0.4467 -1.0 1379043 ChemDiv3_004214 Fc1ccccc1Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P13 compound treatment 0.465 0.212 11.38 11.3756 1.0 3120041 ChemDiv3_004215 Cc1cc(C(=O)CSc2ncnc3sc4CCCCc4c23)c(C)n1Cc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P14 compound treatment 0.399 0.146 7.83 7.8289 1.0 3024070 ChemDiv3_004216 CN1C(=O)/C(=C/Nc2cccc(Cl)c2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P15 compound treatment 0.274 0.0207 1.11 1.1117 1.0 1257595 ChemDiv3_004217 OC(=O)CSc1nnc-2c(OC3(CCCC3)Nc4ccccc42)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P16 compound treatment 0.477 0.224 12.02 12.0205 1.0 3024074 ChemDiv3_004218 CN1C(=O)/C(=C\Nc2cccc(CO)c2)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P17 compound treatment 0.267 0.0137 0.74 0.7355 1.0 3120042 ChemDiv3_004219 Cc1ccc(Oc2ncnc3sccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P18 compound treatment 0.345 0.0917 4.93 4.9271 1.0 3024079 ChemDiv3_004220 CC1=N/C(=C/c2cc3ccccc3nc2Sc4ccc(C)cc4)/C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P19 compound treatment 0.261 0.00769 0.41 0.4131 1.0 1244804 ChemDiv3_004221 COc1ccc(cc1OC)C(=O)Nn2c(C)nnc2n3nc(C)cc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P20 compound treatment 0.272 0.0187 1.0 1.0042 1.0 3120043 ChemDiv3_004222 CC(C)CN(CC(C)C)CN1CC(COc2ccccc2C)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P21 compound treatment 0.25 -0.00331 -0.18 -0.178 -1.0 3023284 ChemDiv3_004223 COC(=O)C1=CN(C=C(C1c2cccc(OC)c2)C(=O)OC)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P22 compound treatment 0.309 0.0557 2.99 2.9925 1.0 1820755 ChemDiv3_004224 O=C(CSc1nnnn1c2ccccc2)N3c4ccccc4CCc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P23 mock treatment 0.258 0.00469 0.25 0.2519 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2012 P24 mock treatment 0.273 0.0197 1.06 1.058 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A01 compound treatment 0.262 -0.00674 -0.36 -0.3623 -1.0 1609023 TimTec1_001409 COc1ccc(CC(=O)n2[nH]c(=O)ccc2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A02 compound treatment 0.46 0.191 10.28 10.2778 1.0 3210400 TimTec1_001410 CCN1C/C(=C\c2ccc3OCOc3c2)/C(=O)\C(=C\c4ccc5OCOc5c4)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A03 compound treatment 0.26 -0.00874 -0.47 -0.4698 -1.0 3210401 TimTec1_001411 OCC1OC(C(O)C1O)N2C3CCNC(=O)C3N=C2N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A04 compound treatment 0.362 0.0933 5.01 5.0115 1.0 1501937 TimTec1_001412 O=C(Nc1cccc(c1)N2CCCC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A05 compound treatment 0.284 0.0153 0.82 0.8199 1.0 1302244 TimTec1_001413 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A06 compound treatment 0.284 0.0153 0.82 0.8199 1.0 3082998 TimTec1_001414 Nc1nc(SCc2ccccc2)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A07 compound treatment 0.293 0.0243 1.3 1.3036 1.0 1224047 TimTec1_001415 COc1ccccc1c2nn(CNc3ccccc3)c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A08 compound treatment 0.347 0.0783 4.21 4.2054 1.0 3083000 TimTec1_001416 CCOC(=O)c1sc(SC)nc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A09 compound treatment 0.259 -0.00974 -0.52 -0.5235 -1.0 1232083 TimTec1_001417 Brc1ccc2C(=O)N(C(c3ccccc3)c4ccccc4)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A10 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1258394 TimTec1_001418 CCN(CC)C(=O)c1c[nH]c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A11 compound treatment 0.261 -0.00774 -0.42 -0.416 -1.0 1352649 TimTec1_001419 C(N1CCCN(Cc2ccccc2)C1c3ccncc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A12 compound treatment 0.374 0.105 5.66 5.6563 1.0 1285436 TimTec1_001420 Brc1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A13 compound treatment 0.264 -0.00474 -0.25 -0.2548 -1.0 3210402 TimTec1_001421 COc1cc(cc(OC)c1OC)C/2=NOC(=O)\C2=C/c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A14 compound treatment 0.28 0.0113 0.6 0.605 1.0 3083004 TimTec1_001422 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4cccnc4)C(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A15 compound treatment 0.329 0.0603 3.24 3.2381 1.0 3210403 TimTec1_001423 CSc1sc(C)cc1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A16 compound treatment 0.448 0.179 9.63 9.633 1.0 1473282 TimTec1_001424 N=c1[nH]c(cs1)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A17 compound treatment 0.398 0.129 6.95 6.9461 1.0 1291516 TimTec1_001425 Nc1nonc1NC(=O)CSc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A18 compound treatment 0.357 0.0883 4.74 4.7428 1.0 1069221 TimTec1_001426 CSc1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A19 compound treatment 0.432 0.163 8.77 8.7731 1.0 1502089 TimTec1_001427 COc1ccc(cc1)C2C3CCC=C3C(=C(N)C2(C#N)C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A20 compound treatment 0.317 0.0483 2.59 2.5933 1.0 1057528 TimTec1_001428 CC(=O)Oc1cccc2ccc(O)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A21 compound treatment 0.284 0.0153 0.82 0.8199 1.0 3210521 TimTec1_001429 Cc1c(C)c(/C=N/O)c(C)c(C)c1/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A22 compound treatment 0.272 0.00326 0.18 0.1751 1.0 1551108 TimTec1_001430 CCOC(=O)C1CCN(CC1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A23 mock treatment 0.274 0.00526 0.28 0.2826 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 A24 mock treatment 0.293 0.0243 1.3 1.3036 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B01 compound treatment 0.422 0.153 8.24 8.2358 1.0 1318272 TimTec1_001431 COc1ccc2nc(sc2c1)C(=O)N3CCN(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B02 compound treatment 0.603 0.334 17.96 17.9623 1.0 1256461 TimTec1_001432 OC(=O)c1ccc(Nc2nnc(c3ccccc3)c(n2)c4ccccc4)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B03 compound treatment 0.465 0.196 10.55 10.5465 1.0 3083011 TimTec1_001433 FC(F)(F)c1cccc(c1)c2ccc(/C=C(\C#N)/c3ccccc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B04 compound treatment 0.296 0.0273 1.46 1.4648 1.0 3210522 TimTec1_001434 C(C1COC(=N1)C2=N[C@@H](Cc3ccccc3)CO2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B05 compound treatment 0.325 0.0563 3.02 3.0232 1.0 3083012 TimTec1_001435 Cc1nnc(/N=C/2\S/C(=C/c3ccc(cc3)C(=O)O)/C(=O)N2CC=C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B06 compound treatment 0.267 -0.00174 -0.09 -0.0936 -1.0 3210523 TimTec1_001436 C/C(=N\O)/c1ccc2OCCOCCOCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B07 compound treatment 0.309 0.0403 2.16 2.1634 1.0 1208416 TimTec1_001437 O=C1N(CSc2nc3ccccc3s2)c4cccc5cccc1c45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B08 compound treatment 0.28 0.0113 0.6 0.605 1.0 3210524 TimTec1_001438 C[C@@H]1[C@@H]2CCC3[C@@](C)(CC(=O)O)CCC[C@]3(C)C2Cc4occc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B09 compound treatment 0.289 0.0203 1.09 1.0886 1.0 1668666 TimTec1_001439 C(SCc1ccccc1)c2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B10 compound treatment 0.406 0.137 7.38 7.376 1.0 3210525 TimTec1_001440 ONC(=O)c1cccc2/C(=N\O)/c3ccccc3-c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B11 compound treatment 0.519 0.25 13.45 13.4483 1.0 3083091 TimTec1_001441 CCCOc1ccc(/C=C/C(=O)Nc2nnc[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B12 compound treatment 0.453 0.184 9.9 9.9016 1.0 1621908 TimTec1_001442 NS(=O)(=O)c1nn2cc(nc2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B13 compound treatment 0.337 0.0683 3.67 3.668 1.0 1239473 TimTec1_001443 Clc1c(NCc2ccccc2)cn[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B14 compound treatment 0.407 0.138 7.43 7.4297 1.0 3210526 TimTec1_001444 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)/C=C/c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B15 compound treatment 0.421 0.152 8.18 8.182 1.0 3210527 TimTec1_001445 Brc1cc(c2coc3ccccc3c2=O)c4OCOCc4c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B16 compound treatment 0.445 0.176 9.47 9.4717 1.0 3083094 TimTec1_001446 COc1cc(SC#N)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B17 compound treatment 0.413 0.144 7.75 7.7521 1.0 1121522 TimTec1_001447 COc1ccc(CCCc2nc3ccccc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B18 compound treatment 0.269 2.58E-4 0.01 0.0139 1.0 3210528 TimTec1_001448 CNC(=S)Nc1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B19 compound treatment 0.52 0.251 13.5 13.5021 1.0 1022826 TimTec1_001449 O=C(Nc1ccccc1)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B20 compound treatment 0.288 0.0193 1.03 1.0349 1.0 3083097 TimTec1_001450 CC1CCCCN1C(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B21 compound treatment 0.316 0.0473 2.54 2.5395 1.0 3210529 TimTec1_001451 O=C(NCc1ccco1)c2ccccc2N(Cc3ccccc3)S(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B22 compound treatment 0.29 0.0213 1.14 1.1424 1.0 1271782 TimTec1_001452 CC(=O)Oc1ccc2c(NC3(OC(=O)C)C(=O)c4ccccc4C23OC(=O)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B23 mock treatment 0.27 0.00126 0.07 0.0676 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 B24 mock treatment 0.258 -0.0107 -0.58 -0.5772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C01 compound treatment 0.262 -0.00674 -0.36 -0.3623 -1.0 1645231 TimTec1_001453 CCn1cnc2c(=O)[nH][nH]c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C02 compound treatment 0.328 0.0593 3.18 3.1844 1.0 2086755 TimTec1_001454 CCOC(=O)N1C/C(=C\c2ccccc2)/C(=O)\C(=C\c3ccccc3)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C03 compound treatment 0.304 0.0353 1.89 1.8947 1.0 1308938 TimTec1_001455 CCc1cc2c(=O)c(coc2cc1OC(C)C(=O)O)c3csc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C04 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1446072 TimTec1_001456 CC1CCCN(C1)C(=O)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C05 compound treatment 0.468 0.199 10.71 10.7077 1.0 1636408 TimTec1_001457 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)OCc4ccccc4)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C06 compound treatment 0.423 0.154 8.29 8.2895 1.0 3083101 TimTec1_001458 Nc1n/c(=N\c2ccccc2)/ss1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C07 compound treatment 0.266 -0.00274 -0.15 -0.1473 -1.0 1676195 TimTec1_001459 CCSc1nc2ccccc2n1CC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C08 compound treatment 0.551 0.282 15.17 15.168 1.0 3083103 TimTec1_001460 CSc1nc(N)c(s1)C(=O)Nc2ccc(cc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C09 compound treatment 0.459 0.19 10.22 10.2241 1.0 3210530 TimTec1_001461 Cc1nc2ccc(/N=C/c3ccccc3O)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C10 compound treatment 0.333 0.0643 3.45 3.4531 1.0 1342383 TimTec1_001462 O=C(N(Cc1ccccc1)Cc2ccccc2)c3c[nH]c4ccccc4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C11 compound treatment 0.267 -0.00174 -0.09 -0.0936 -1.0 1668351 TimTec1_001463 OC(=O)C1CCCN1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C12 compound treatment 0.302 0.0333 1.79 1.7872 1.0 1266673 TimTec1_001464 O=C(Nc1ncccn1)c2c[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C13 compound treatment 0.281 0.0123 0.66 0.6587 1.0 3083106 TimTec1_001465 Fc1ccccc1C/2=NOC(=O)\C2=C/Nc3ccc(Cl)cn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C14 compound treatment 0.297 0.0283 1.52 1.5185 1.0 1516165 TimTec1_001466 CCOC(=O)C1=C(C)OC(=C(C1c2cccnc2)C(=O)OCC)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C15 compound treatment 0.285 0.0163 0.87 0.8737 1.0 3083108 TimTec1_001467 CSc1sc(C)cc1/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C16 compound treatment 0.414 0.145 7.81 7.8059 1.0 3210531 TimTec1_001468 Clc1ccc(NC(=O)/N=c/2\[nH]c(cs2)c3ccccc3)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C17 compound treatment 0.482 0.213 11.46 11.46 1.0 3083183 TimTec1_001469 Nc1nonc1NC(=O)CSC(=N)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C18 compound treatment 0.274 0.00526 0.28 0.2826 1.0 1579055 TimTec1_001470 COc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C19 compound treatment 0.349 0.0803 4.31 4.3129 1.0 1328959 TimTec1_001471 CCOc1ccc(OCC)c(c1)C2C(Cc3ccccc3)N4C(C=Cc5ccccc45)C2(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C20 compound treatment 0.286 0.0173 0.93 0.9274 1.0 3083185 TimTec1_001472 COC(=O)Nc1nccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C21 compound treatment 0.35 0.0813 4.37 4.3666 1.0 1288354 TimTec1_001473 Cc1ccc(c(C)c1)c2c(C#N)c(N)n(C)c(=O)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C22 compound treatment 0.302 0.0333 1.79 1.7872 1.0 1283442 TimTec1_001474 O=C(Nc1ccc2OCOc2c1)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C23 mock treatment 0.281 0.0123 0.66 0.6587 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 C24 mock treatment 0.287 0.0183 0.98 0.9812 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D01 compound treatment 0.386 0.117 6.3 6.3012 1.0 3083186 TimTec1_001475 O=C1CC(Sc2ccc3ccccc3c2)C4COC1O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D02 compound treatment 0.282 0.0133 0.71 0.7125 1.0 1501922 TimTec1_001476 OC(=O)c1nn(Cc2ccccc2)nc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D03 compound treatment 0.339 0.0703 3.78 3.7755 1.0 3210532 TimTec1_001477 S/C(=C(/C(=O)c1ccccc1)\[n+]2ccccc2)/NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D04 compound treatment 0.272 0.00326 0.18 0.1751 1.0 3083190 TimTec1_001478 O=C(N[C@@H]1COC(=O)C1)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D05 compound treatment 0.355 0.0863 4.64 4.6353 1.0 3210533 TimTec1_001479 O=C(C(=C1Nc2ccccc2N1)C#N)c3cc[n+](Cc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D06 compound treatment 0.292 0.0233 1.25 1.2498 1.0 3083192 TimTec1_001480 OC(=O)c1ccc(/C=C/C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D07 compound treatment 0.322 0.0533 2.86 2.862 1.0 1703831 TimTec1_001481 Brc1ccc(NC(=O)C2(CCN3CC2)c4ccccc4C3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D08 compound treatment 0.282 0.0133 0.71 0.7125 1.0 1474907 TimTec1_001482 OC1CC(c2ccccc2Cl)C3(C(C1)c4ccccc4Cl)C(=O)NC(=O)NC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D09 compound treatment 0.274 0.00526 0.28 0.2826 1.0 3210647 TimTec1_001483 Cc1cccn2c(=O)c(/C=N/c3ccc(Cl)cc3)c(Sc4ccccc4)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D10 compound treatment 0.561 0.292 15.71 15.7053 1.0 3083196 TimTec1_001484 Cc1ccc(cc1)S(=O)(=O)c2ccc(/C=C/c3ccco3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D11 compound treatment 0.46 0.191 10.28 10.2778 1.0 1185515 TimTec1_001485 O=C(NCCc1nc2ccccc2[nH]1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D12 compound treatment 0.489 0.22 11.84 11.8362 1.0 3083198 TimTec1_001486 COc1ccc(/C=C/2\N=C(N(C2=O)c3nc4ccc(cc4s3)C(=O)O)c5ccccc5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D13 compound treatment 0.56 0.291 15.65 15.6516 1.0 1329192 TimTec1_001487 Cc1cc(=O)n2c3C(=O)N(Cc4ccccc4)C(=O)c3sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D14 compound treatment 0.286 0.0173 0.93 0.9274 1.0 3210648 TimTec1_001488 CC(=O)Nc1ccc(cc1C(=O)O)S(=O)(=O)NN2C(=O)/C(=C/c3ccco3)/N=C2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D15 compound treatment 0.285 0.0163 0.87 0.8737 1.0 3083200 TimTec1_001489 Cc1nnc(C)n1/N=C/c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D16 compound treatment 0.555 0.286 15.38 15.3829 1.0 1026134 TimTec1_001490 O=C(c1cc2ccccc2o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D17 compound treatment 0.34 0.0713 3.83 3.8293 1.0 1337169 TimTec1_001491 CCCC(=O)c1ccc(cc1)C(C)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D18 compound treatment 0.274 0.00526 0.28 0.2826 1.0 1082112 TimTec1_001492 COc1cccc(NC(=S)Nc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D19 compound treatment 0.266 -0.00274 -0.15 -0.1473 -1.0 1198422 TimTec1_001493 NC(=O)CCNC(=O)C(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D20 compound treatment 0.284 0.0153 0.82 0.8199 1.0 1112637 TimTec1_001494 CCC(C)NC(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D21 compound treatment 0.428 0.159 8.56 8.5582 1.0 3210649 TimTec1_001495 Fc1ccc(cc1)c2cs/c(=N\c3ccccc3)/n2Cc4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D22 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1228411 TimTec1_001496 OC1(C2C(=O)NC(=O)NC2=O)C(=O)c3ccccc3C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D23 mock treatment 0.264 -0.00474 -0.25 -0.2548 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 D24 mock treatment 0.259 -0.00974 -0.52 -0.5235 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E01 compound treatment 0.276 0.00726 0.39 0.39 1.0 1636299 TimTec1_001497 COc1ccc2C=CC3C=CC(O)C4Oc1c2C43CCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E02 compound treatment 0.287 0.0183 0.98 0.9812 1.0 3083205 TimTec1_001498 CC(C)(C)C1C/C(=C\c2ccc3OCOc3c2)/C(=O)\C(=C\c4ccc5OCOc5c4)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E03 compound treatment 0.278 0.00926 0.5 0.4975 1.0 3210650 TimTec1_001499 Cn1c(=O)c(C2=NNC3=NNC(C23)c4ccccc4)c(O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E04 compound treatment 0.272 0.00326 0.18 0.1751 1.0 3083208 TimTec1_001500 O=C(N1CCCCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E05 compound treatment 0.305 0.0363 1.95 1.9484 1.0 1501857 TimTec1_001501 COc1ccc(NC(=O)CC2CS(=O)(=O)CC2CC(=O)Nc3ccc(OC)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E06 compound treatment 0.266 -0.00274 -0.15 -0.1473 -1.0 1493097 TimTec1_001502 CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n2cnnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E07 compound treatment 0.296 0.0273 1.46 1.4648 1.0 3210651 TimTec1_001503 Oc1ccc(/C=N/c2ccc(cc2)N3CCOCC3)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E08 compound treatment 0.271 0.00226 0.12 0.1213 1.0 1097150 TimTec1_001504 COc1ccc(NC(=O)c2sc(SC)nc2N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E09 compound treatment 0.463 0.194 10.44 10.439 1.0 3210652 TimTec1_001505 O=C/1Nc2ccccc2\C1=N/N3C(=O)C4C=CC=CC4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E10 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1413901 TimTec1_001506 O=C(N(c1ccccc1)c2ccccc2)c3c[nH]c4ccccc4c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E11 compound treatment 0.276 0.00726 0.39 0.39 1.0 3210653 TimTec1_001507 CC(C)(C)C(=O)CSc1ncnc2[nH]cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E12 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1279481 TimTec1_001508 CCOC(=O)CC(N)c1ccccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E13 compound treatment 0.402 0.133 7.16 7.161 1.0 3210654 TimTec1_001509 CCc1sc2sncc2c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E14 compound treatment 0.281 0.0123 0.66 0.6587 1.0 1490642 TimTec1_001510 Cc1ccc(s1)C(C2C(=O)CC(C)(C)CC2=O)C3C(=O)CC(C)(C)CC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E15 compound treatment 0.386 0.117 6.3 6.3012 1.0 3082121 TimTec1_001511 CCSc1cc(CC)sc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E16 compound treatment 0.299 0.0303 1.63 1.626 1.0 3082123 TimTec1_001512 CN(C(=O)CSC(=S)N1CCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E17 compound treatment 0.377 0.108 5.82 5.8176 1.0 3210655 TimTec1_001513 CCOC(=O)/C=C(/C)\Nc1nonc1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E18 compound treatment 0.481 0.212 11.41 11.4063 1.0 3082125 TimTec1_001514 Nc1nnc(o1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E19 compound treatment 0.319 0.0503 2.7 2.7008 1.0 1386928 TimTec1_001515 Cc1ccc(C2C(Cc3ccccc3)N4C=Cc5ccccc5C4C2(C#N)C(=O)N)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E20 compound treatment 0.309 0.0403 2.16 2.1634 1.0 3082127 TimTec1_001516 CCOC(=O)Cc1ccccc1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E21 compound treatment 0.649 0.38 20.43 20.4343 1.0 3210656 TimTec1_001517 O=C/1/C(=C/C2CCCO2)/CC\C1=C/C3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E22 compound treatment 0.518 0.249 13.39 13.3946 1.0 1433367 TimTec1_001518 CC(C)C(=O)Nc1ccc(cc1)c2nc3cc(C)ccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E23 mock treatment 0.273 0.00426 0.23 0.2288 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 E24 mock treatment 0.273 0.00426 0.23 0.2288 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F01 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1232600 TimTec1_001519 COCC(=O)OCC1CCCN2CCCCC12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F02 compound treatment 0.28 0.0113 0.6 0.605 1.0 3082129 TimTec1_001520 CC(=O)OCc1cnn(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F03 compound treatment 0.354 0.0853 4.58 4.5816 1.0 3210657 TimTec1_001521 O=C(CCCN1C(=O)S/C(=C/c2ccccc2)/C1=S)NC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F04 compound treatment 0.31 0.0413 2.22 2.2171 1.0 1023719 TimTec1_001522 Clc1ncnc2n(cnc12)C3CCCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F05 compound treatment 0.373 0.104 5.6 5.6026 1.0 3210658 TimTec1_001523 CCc1nnc(/N=C/2\S/C(=C/c3ccc(cc3)C(=O)O)/C(=O)N2CC=C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F06 compound treatment 0.293 0.0243 1.3 1.3036 1.0 3082133 TimTec1_001524 Brc1ccc(/C=C/C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F07 compound treatment 0.561 0.292 15.71 15.7053 1.0 3082134 TimTec1_001525 Nc1nnc(CCN2C(=O)S/C(=C/c3ccccc3)/C2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F08 compound treatment 0.261 -0.00774 -0.42 -0.416 -1.0 1022021 TimTec1_001526 CC1(C)OC2C(CO)OC(C2O1)n3cnc4c(O)ncnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F09 compound treatment 0.308 0.0393 2.11 2.1096 1.0 3210659 TimTec1_001527 OC(=O)COc1ccccc1/C=N/N2CCN(Cc3ccc(Cl)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F10 compound treatment 0.493 0.224 12.05 12.0512 1.0 3210660 TimTec1_001528 CN(C)c1ccc(cc1)C2=NN(C(C2)NC(Cc3c[nH]c4ccccc34)C(=O)O)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F11 compound treatment 0.298 0.0293 1.57 1.5723 1.0 1300950 TimTec1_001529 O=C(CN1C(=O)c2ccccc2C1=O)Nc3nnc[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F12 compound treatment 0.291 0.0223 1.2 1.1961 1.0 1127108 TimTec1_001530 CCC(Sc1nc2cccc(CC)c2c(=O)n1c3ccc(OC)cc3)C(=O)NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F13 compound treatment 0.488 0.219 11.78 11.7825 1.0 3082764 TimTec1_001531 Clc1nc(C#N)c(C#N)nc1C(=C2Nc3ccccc3N2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F14 compound treatment 0.355 0.0863 4.64 4.6353 1.0 3210661 TimTec1_001532 CC(C)C(C(=O)NN1C(=O)/C(=C/c2ccccn2)/N=C1c3ccccc3)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F15 compound treatment 0.407 0.138 7.43 7.4297 1.0 3082765 TimTec1_001533 C/C=C(/C)\C(=O)OC1CC(O)(C(C)C)C2C(CC(=CCC12C)C)OC(=O)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F16 compound treatment 0.274 0.00526 0.28 0.2826 1.0 1203282 TimTec1_001534 CC(O)CNC(=O)C1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F17 compound treatment 0.281 0.0123 0.66 0.6587 1.0 1114140 TimTec1_001535 COc1ccc(CCCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F18 compound treatment 0.274 0.00526 0.28 0.2826 1.0 1082103 TimTec1_001536 Fc1ccc(NC(=S)Nc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F19 compound treatment 0.372 0.103 5.55 5.5489 1.0 1119735 TimTec1_001537 COc1ccc2[nH]cc(CCNC(=O)c3ccco3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F20 compound treatment 0.332 0.0633 3.4 3.3994 1.0 3210662 TimTec1_001538 CCOC(=O)C1=C(Nc2ccccc2)OCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F21 compound treatment 0.302 0.0333 1.79 1.7872 1.0 3082768 TimTec1_001539 CC(C)NCC(O)COc1ccc(/C=C/c2cc(C)no2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F22 compound treatment 0.29 0.0213 1.14 1.1424 1.0 3210663 TimTec1_001540 O=C1C(/C(=N/c2ccccc2)/c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F23 mock treatment 0.275 0.00626 0.34 0.3363 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 F24 mock treatment 0.252 -0.0167 -0.9 -0.8997 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G01 compound treatment 0.467 0.198 10.65 10.654 1.0 3210787 TimTec1_001541 CC1=C(NC(=S)NC(=O)c2ccccc2)NCc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G02 compound treatment 0.291 0.0223 1.2 1.1961 1.0 3082771 TimTec1_001542 N#C/C(=C\c1ccccc1/C=C(\C#N)/c2ccc3OCOc3c2)/c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G03 compound treatment 0.261 -0.00774 -0.42 -0.416 -1.0 3210788 TimTec1_001543 OC(=O)CC1N=Cc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G04 compound treatment 0.286 0.0173 0.93 0.9274 1.0 3210789 TimTec1_001544 C1Oc2ccc(/C=C/C=N/c3ccc(cc3)N4CCOCC4)cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G05 compound treatment 0.275 0.00626 0.34 0.3363 1.0 1707466 TimTec1_001545 CN1CCN(CC(O)COc2ccccc2OCc3nc(C)no3)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G06 compound treatment 0.325 0.0563 3.02 3.0232 1.0 3210790 TimTec1_001546 CC1=C(Oc2ccccc2N1)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G07 compound treatment 0.344 0.0753 4.04 4.0442 1.0 1121781 TimTec1_001547 Cc1ccc(C)n1c2ccc(cc2)C(=O)OCC(=O)c3c(C)c(C)cc(C)c3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G08 compound treatment 0.593 0.324 17.42 17.425 1.0 1240166 TimTec1_001548 Nc1[nH]c(=S)sc1C(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G09 compound treatment 0.271 0.00226 0.12 0.1213 1.0 3082775 TimTec1_001549 Brc1ccc(cc1)C2OCC(=S)N2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G10 compound treatment 0.292 0.0233 1.25 1.2498 1.0 1301555 TimTec1_001550 CC(C)N(CCC#N)C(=O)c1c[nH]c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G11 compound treatment 0.279 0.0103 0.55 0.5512 1.0 1162047 TimTec1_001551 OC(=O)c1ccccc1C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G12 compound treatment 0.326 0.0573 3.08 3.0769 1.0 1376806 TimTec1_001552 Cc1ccc(C)c(c1)C2C3CCCC=C3C(=C(N)C2(C#N)C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G13 compound treatment 0.396 0.127 6.84 6.8386 1.0 1912519 TimTec1_001553 CN(C)Cc1cc(/C=N/C2CCCCC2)c(S)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G14 compound treatment 0.276 0.00726 0.39 0.39 1.0 1339047 TimTec1_001554 CCc1ccc(s1)C(C2C(=O)CC(C)(C)CC2=O)C3C(=O)CC(C)(C)CC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G15 compound treatment 0.431 0.162 8.72 8.7194 1.0 3082839 TimTec1_001555 CCc1cc2cc(sc2s1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G16 compound treatment 0.279 0.0103 0.55 0.5512 1.0 3210791 TimTec1_001556 Nc1nonc1OCCNc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G17 compound treatment 0.284 0.0153 0.82 0.8199 1.0 1225048 TimTec1_001557 CC(=O)Nc1nonc1NC2=CC(=O)CC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G18 compound treatment 0.29 0.0213 1.14 1.1424 1.0 1004952 TimTec1_001558 OC(c1nc2ccccc2[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G19 compound treatment 0.363 0.0943 5.07 5.0652 1.0 1382010 TimTec1_001559 CCOc1ccc(OCC)c(CC2OC(=NC2=O)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G20 compound treatment 0.535 0.266 14.31 14.3082 1.0 3082843 TimTec1_001560 COc1ccc(/C=C(/C#N)\c2ccc(Cl)cc2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G21 compound treatment 0.475 0.206 11.08 11.0839 1.0 1449158 TimTec1_001561 Brc1cccc(c1)C(CC(=O)c2ccccc2)C(C#N)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G22 compound treatment 0.454 0.185 9.96 9.9554 1.0 1173213 TimTec1_001562 Clc1ccc(Cl)c(OCC(=O)NCc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G23 mock treatment 0.271 0.00226 0.12 0.1213 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 G24 mock treatment 0.266 -0.00274 -0.15 -0.1473 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H01 compound treatment 0.253 -0.0157 -0.85 -0.8459 -1.0 3210792 TimTec1_001563 CN12CCCCC2C(COc3ccccc3Br)CCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H02 compound treatment 0.462 0.193 10.39 10.3853 1.0 3082846 TimTec1_001564 Cc1ccc(cc1)C2=NNC3(CCOC(C)(C)C3)S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H03 compound treatment 0.266 -0.00274 -0.15 -0.1473 -1.0 3210793 TimTec1_001565 Clc1ccccc1/C=N/C2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H04 compound treatment 0.29 0.0213 1.14 1.1424 1.0 1272351 TimTec1_001566 CC(C)(C)c1ccc2OCCOCCOCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H05 compound treatment 0.398 0.129 6.95 6.9461 1.0 3210794 TimTec1_001567 c1nn(c2ccccc2)c3ncn4nnnc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H06 compound treatment 0.281 0.0123 0.66 0.6587 1.0 3082850 TimTec1_001568 COc1cccc(/C=C/C(=O)O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H07 compound treatment 0.311 0.0423 2.27 2.2709 1.0 3210795 TimTec1_001569 COc1ccc(cc1OC)C2=N/C(=C/c3c(C)nn(c3N4CCCCC4)c5ccccc5)/C(=O)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H08 compound treatment 0.309 0.0403 2.16 2.1634 1.0 3210796 TimTec1_001570 Cn1c(=O)c(C/2=NNC(=O)\C2=C/c3c[nH]c4ccccc34)c(O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H09 compound treatment 0.43 0.161 8.67 8.6657 1.0 1574162 TimTec1_001571 CCc1cc(c2n[nH]c(C)c2c3nc4ccccc4n3C)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H10 compound treatment 0.279 0.0103 0.55 0.5512 1.0 1654421 TimTec1_001572 CS(=O)(=O)N(Cc1ccc(cc1)C(=O)O)c2cccc(Cl)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H11 compound treatment 0.275 0.00626 0.34 0.3363 1.0 1562719 TimTec1_001573 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3nnc[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H12 compound treatment 0.535 0.266 14.31 14.3082 1.0 3210797 TimTec1_001574 Clc1ccc(cc1)N(C(=O)Nc2ccccc2Br)C3=NCCS3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H13 compound treatment 0.279 0.0103 0.55 0.5512 1.0 1779116 TimTec1_001575 CCOC(=O)CCc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H14 compound treatment 0.27 0.00126 0.07 0.0676 1.0 3210798 TimTec1_001576 CC(=O)OC1C(OC2C(OC(=O)C)C(=O)OC12)n3ccc(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H15 compound treatment 0.41 0.141 7.59 7.5909 1.0 3082856 TimTec1_001577 CC(C)C1C(O)C/C(=C/CC/C(=C/C1O)/C)/C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H16 compound treatment 0.279 0.0103 0.55 0.5512 1.0 1079739 TimTec1_001578 CS(=O)(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H17 compound treatment 0.295 0.0263 1.41 1.4111 1.0 1036359 TimTec1_001579 Cc1ccc(CCCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H18 compound treatment 0.264 -0.00474 -0.25 -0.2548 -1.0 1014539 TimTec1_001580 S=C(Nc1ccccc1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H19 compound treatment 0.296 0.0273 1.46 1.4648 1.0 1593359 TimTec1_001581 Cc1ccc(cc1)c2nc3sc4C(=O)CC(C)(C)Cc4n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H20 compound treatment 0.457 0.188 10.12 10.1166 1.0 1240459 TimTec1_001582 CCOC(=O)C1C(=O)CN(C1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H21 compound treatment 0.382 0.113 6.09 6.0863 1.0 3082920 TimTec1_001583 CC12CCCCC2N(CCC(=O)N)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H22 compound treatment 0.283 0.0143 0.77 0.7662 1.0 1468638 TimTec1_001584 O=C1c2ccccc2C(=O)C1(Nc3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H23 mock treatment 0.262 -0.00674 -0.36 -0.3623 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 H24 mock treatment 0.258 -0.0107 -0.58 -0.5772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I01 compound treatment 0.505 0.236 12.7 12.696 1.0 1500758 TimTec1_001585 CCC(=O)NC1CC2C(OC1=O)c3cccc(C)c3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I02 compound treatment 0.299 0.0303 1.63 1.626 1.0 3082924 TimTec1_001586 CC1CCC/C(=C\c2ccc3OCOc3c2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I03 compound treatment 0.261 -0.00774 -0.42 -0.416 -1.0 3210799 TimTec1_001587 COC(=O)C1(C)NC2(CCCCC2)Cc3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I04 compound treatment 0.31 0.0413 2.22 2.2171 1.0 1512799 TimTec1_001588 CC(C)(C)C1CCc2c(C1)sc3NC(NC(=O)c23)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I05 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1550718 TimTec1_001589 Cc1noc(COc2ccccc2OCC(=O)N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I06 compound treatment 0.276 0.00726 0.39 0.39 1.0 3082927 TimTec1_001590 Cc1[nH]c(=O)n(c(=O)c1C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I07 compound treatment 0.267 -0.00174 -0.09 -0.0936 -1.0 1716137 TimTec1_001591 CS(=O)(=O)Nc1cc(NS(=O)(=O)C)cc(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I08 compound treatment 0.49 0.221 11.89 11.8899 1.0 1611777 TimTec1_001592 COc1ccc(NC(=O)c2sc(=S)[nH]c2N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I09 compound treatment 0.298 0.0293 1.57 1.5723 1.0 3210800 TimTec1_001593 Cc1ccc(cc1)C(=O)/N=c\2/cccc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I10 compound treatment 0.301 0.0323 1.73 1.7335 1.0 1119826 TimTec1_001594 O=C(N1CCCCC1)c2c[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I11 compound treatment 0.377 0.108 5.82 5.8176 1.0 1603574 TimTec1_001595 Cc1sc(N)c(C(=O)N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I12 compound treatment 0.298 0.0293 1.57 1.5723 1.0 1363974 TimTec1_001596 COC(=O)C1(C#N)C(C(N2C1C=Cc3ccccc23)C(=O)c4ccccc4)c5ccc(C)cc5C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I13 compound treatment 0.262 -0.00674 -0.36 -0.3623 -1.0 1916807 TimTec1_001597 CCS(=O)(=O)c1ccsc1S(=O)(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I14 compound treatment 0.338 0.0693 3.72 3.7218 1.0 3082931 TimTec1_001598 NC1=C(C#N)C2=CCCCC2C(c3cccs3)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I15 compound treatment 0.302 0.0333 1.79 1.7872 1.0 1914041 TimTec1_001599 CSc1sc(SC)c(CO)c1CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I16 compound treatment 0.271 0.00226 0.12 0.1213 1.0 3082933 TimTec1_001600 CC(C)(Oc1ccccc1Cl)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I17 compound treatment 0.282 0.0133 0.71 0.7125 1.0 1737803 TimTec1_001601 CC(=O)Nc1nonc1Nc2cc(C)nn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I18 compound treatment 0.275 0.00626 0.34 0.3363 1.0 3082935 TimTec1_001602 COc1ccccc1C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I19 compound treatment 0.278 0.00926 0.5 0.4975 1.0 1115158 TimTec1_001603 Cc1cc(C)c(C)c(C(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I20 compound treatment 0.285 0.0163 0.87 0.8737 1.0 3210920 TimTec1_001604 CCNC(=S)Nc1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I21 compound treatment 0.305 0.0363 1.95 1.9484 1.0 3082938 TimTec1_001605 Clc1ccc(/C(=C\c2ccc3OCOc3c2)/C#N)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I22 compound treatment 0.283 0.0143 0.77 0.7662 1.0 1045982 TimTec1_001606 NC(=O)NS(=O)(=O)c1ccc(N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I23 mock treatment 0.293 0.0243 1.3 1.3036 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 I24 mock treatment 0.267 -0.00174 -0.09 -0.0936 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J01 compound treatment 0.34 0.0713 3.83 3.8293 1.0 1479505 TimTec1_001607 OCCOc1c(Cl)cc(Cl)c2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J02 compound treatment 0.469 0.2 10.76 10.7614 1.0 1009854 TimTec1_001608 COc1ccc(cc1)C(O)C(=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J03 compound treatment 0.463 0.194 10.44 10.439 1.0 3082941 TimTec1_001609 Cc1sc(/N=C/c2ccc(Br)s2)c(C(=O)N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J04 compound treatment 0.271 0.00226 0.12 0.1213 1.0 1144212 TimTec1_001610 OC(=O)c1ccc2OCCOCCOCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J05 compound treatment 0.391 0.122 6.57 6.5699 1.0 3210921 TimTec1_001611 Cc1nnc(/N=C/2\S/C(=C/c3ccccc3F)/C(=O)N2CC=C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J06 compound treatment 0.279 0.0103 0.55 0.5512 1.0 1115371 TimTec1_001612 COc1ccc(cc1)C(N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J07 compound treatment 0.285 0.0163 0.87 0.8737 1.0 3083016 TimTec1_001613 Brc1ccc(cc1)N2C(=O)C3ON(C(/C=C/c4ccccc4)C3C2=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J08 compound treatment 0.265 -0.00374 -0.2 -0.2011 -1.0 1351925 TimTec1_001614 CCOC(=O)c1[nH]c(C(=O)O)c(C(=O)OCc2ccccc2)c1CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J09 compound treatment 0.282 0.0133 0.71 0.7125 1.0 3083019 TimTec1_001615 COc1cccc(/N=C/C2=C3N(CCC2)c4ccccc4C3(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J10 compound treatment 0.348 0.0793 4.26 4.2592 1.0 1286584 TimTec1_001616 O=C(NCCc1c[nH]c2ccc(OCc3ccccc3)cc12)C4CCCNC4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J11 compound treatment 0.364 0.0953 5.12 5.119 1.0 1208195 TimTec1_001617 NNC(=O)c1cc(n[nH]1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J12 compound treatment 0.263 -0.00574 -0.31 -0.3086 -1.0 3083022 TimTec1_001618 CC(N)(Cc1ccc2OCOc2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J13 compound treatment 0.283 0.0143 0.77 0.7662 1.0 3210922 TimTec1_001619 CN(C)c1ccc(/C=C\2/C(=NN(C2=O)c3nnc(C)c(=O)[nH]3)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J14 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1414476 TimTec1_001620 Cc1ccc(NC(=O)c2cccc3-c4ccccc4C(=O)c32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J15 compound treatment 0.566 0.297 15.97 15.974 1.0 1395626 TimTec1_001621 CC1C(=O)CCC2C(C)(COc3ccc4ccc(=O)oc4c3)CCCC12C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J16 compound treatment 0.27 0.00126 0.07 0.0676 1.0 1361860 TimTec1_001622 CC1(C)COC(OC1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J17 compound treatment 0.357 0.0883 4.74 4.7428 1.0 3083025 TimTec1_001623 CC(=CC(=O)Nc1ccc(Cl)cc1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J18 compound treatment 0.271 0.00226 0.12 0.1213 1.0 3210923 TimTec1_001624 COc1ccccc1C(=O)N(C(C)C)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J19 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1015339 TimTec1_001625 OC(c1ccccc1)C(O)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J20 compound treatment 0.293 0.0243 1.3 1.3036 1.0 1921357 TimTec1_001626 Brc1ccccc1C2OCC3(CO2)COC(OC3)c4ccccc4Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J21 compound treatment 0.312 0.0433 2.32 2.3246 1.0 3083029 TimTec1_001627 C[C@]1(CCC[C@]2(C)[C@H]3CC(O)[C@](C)(C=C)C=C3CC[C@@H]12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J22 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1236876 TimTec1_001628 OCCC1(C(=O)c2ccccc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J23 mock treatment 0.253 -0.0157 -0.85 -0.8459 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 J24 mock treatment 0.258 -0.0107 -0.58 -0.5772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K01 compound treatment 0.399 0.13 7.0 6.9998 1.0 1634606 TimTec1_001629 CCn1c(=O)c2C(=Nc3cc(C)ccc3Oc2c4ccccc14)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K02 compound treatment 0.309 0.0403 2.16 2.1634 1.0 3083031 TimTec1_001630 COc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K03 compound treatment 0.292 0.0233 1.25 1.2498 1.0 3210924 TimTec1_001631 COc1ccc(cc1)C2CC(=NC(=N)N2)c3cc(OC)cc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K04 compound treatment 0.464 0.195 10.49 10.4928 1.0 3210925 TimTec1_001632 OC(=O)c1cccc(c1)c2ccc(/C=N\n3cnnc3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K05 compound treatment 0.496 0.227 12.21 12.2124 1.0 1250333 TimTec1_001633 CCOC(=O)CSc1cc(Cl)c2cccc(C)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K06 compound treatment 0.283 0.0143 0.77 0.7662 1.0 1029874 TimTec1_001634 CCOC(=O)C1(O)c2ccccc2-c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K07 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1426581 TimTec1_001635 CC(C)c1cc(NC(=O)c2ccccc2)c(C)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K08 compound treatment 0.453 0.184 9.9 9.9016 1.0 1278979 TimTec1_001636 CN(C)c1ccc(NC(=O)c2sc(=S)[nH]c2N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K09 compound treatment 0.265 -0.00374 -0.2 -0.2011 -1.0 3083036 TimTec1_001637 OC(=O)/C=C\C(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K10 compound treatment 0.288 0.0193 1.03 1.0349 1.0 1138966 TimTec1_001638 O=C(NC1CCCCC1)c2c[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K11 compound treatment 0.608 0.339 18.23 18.231 1.0 3210926 TimTec1_001639 CN(C1CCCCC1)C(=O)CCCOc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K12 compound treatment 0.476 0.207 11.14 11.1376 1.0 1449748 TimTec1_001640 Fc1ccc(cc1)C2C(C3C=Cc4ccccc4N3C2(C#N)C#N)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K13 compound treatment 0.269 2.58E-4 0.01 0.0139 1.0 3083110 TimTec1_001641 CS(=O)(=O)c1ccc(s1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K14 compound treatment 0.367 0.0983 5.28 5.2802 1.0 1649383 TimTec1_001642 Cc1ccc(s1)C2C3CCCC=C3C(C#N)C(N)C2(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K15 compound treatment 0.309 0.0403 2.16 2.1634 1.0 3083113 TimTec1_001643 CC1(C)C(c2nc(no2)c3ccc(Br)cc3)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K16 compound treatment 0.252 -0.0167 -0.9 -0.8997 -1.0 1072463 TimTec1_001644 Oc1ccc(cc1)C(c2ccc(O)cc2)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K17 compound treatment 0.281 0.0123 0.66 0.6587 1.0 3083115 TimTec1_001645 COc1cc(/C=N/c2nonc2NC(=O)C)ccc1OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K18 compound treatment 0.338 0.0693 3.72 3.7218 1.0 1266444 TimTec1_001646 OC(=O)c1ccc(COc2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K19 compound treatment 0.294 0.0253 1.36 1.3573 1.0 1199220 TimTec1_001647 COc1ccc(cc1)C2C(C(=O)N)C2(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K20 compound treatment 0.274 0.00526 0.28 0.2826 1.0 3083117 TimTec1_001648 CCNC(=S)Nc1c(C)cccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K21 compound treatment 0.542 0.273 14.68 14.6843 1.0 3210927 TimTec1_001649 O=C/1/C(=C/c2cccc3OCOc32)/CCC\C1=C/c4cccc5OCOc54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K22 compound treatment 0.29 0.0213 1.14 1.1424 1.0 1204849 TimTec1_001650 Oc1ccc2c(=O)c(coc2c1CN3CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K23 mock treatment 0.268 -7.42E-4 -0.04 -0.0399 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 K24 mock treatment 0.267 -0.00174 -0.09 -0.0936 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L01 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1427041 TimTec1_001651 C(Cn1c2ccccc2c3ccccc13)c4nc5ccccc5[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L02 compound treatment 0.295 0.0263 1.41 1.4111 1.0 1045556 TimTec1_001652 COc1ccc2[n+]([O-])cccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L03 compound treatment 0.617 0.348 18.71 18.7147 1.0 3210928 TimTec1_001653 O=C(N1CCN(CC1)C2=NC(=O)/C(=C/c3cccs3)/S2)c4cc5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L04 compound treatment 0.297 0.0283 1.52 1.5185 1.0 3083122 TimTec1_001654 COc1ccc(/C=C/C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L05 compound treatment 0.416 0.147 7.91 7.9133 1.0 1566626 TimTec1_001655 Fc1ccc(cc1)C(CC(=O)c2cccs2)SCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L06 compound treatment 0.312 0.0433 2.32 2.3246 1.0 1449697 TimTec1_001656 CC1Cc2cc(OCC(=O)O)ccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L07 compound treatment 0.344 0.0753 4.04 4.0442 1.0 3083124 TimTec1_001657 NC1=Cc2ccccc2CN1c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L08 compound treatment 0.357 0.0883 4.74 4.7428 1.0 3210929 TimTec1_001658 COc1ccc(cc1)N2CC(=O)N(/N=C/c3ccccc3C(=O)O)C2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L09 compound treatment 0.31 0.0413 2.22 2.2171 1.0 1667441 TimTec1_001659 NC(=O)c1ccccc1NC(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L10 compound treatment 0.349 0.0803 4.31 4.3129 1.0 1921446 TimTec1_001660 CC1=CC(=O)N(CCc2c[nH]c3ccc(OCc4ccccc4)cc23)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L11 compound treatment 0.525 0.256 13.77 13.7708 1.0 1703270 TimTec1_001661 Nc1c(C#N)c2nc(C#N)c(C#N)nc2n1Cc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L12 compound treatment 0.323 0.0543 2.92 2.9157 1.0 1414477 TimTec1_001662 CC(C)Cc1ccc(cc1)C(C)C(=O)NCCc2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L13 compound treatment 0.455 0.186 10.01 10.0091 1.0 1436746 TimTec1_001663 Nc1c(C#N)c2nc(C#N)c(C#N)nc2n1CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L14 compound treatment 0.279 0.0103 0.55 0.5512 1.0 1148985 TimTec1_001664 CCCCC1(SCCS1)c2cc(O)cc(O)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L15 compound treatment 0.53 0.261 14.04 14.0395 1.0 3083129 TimTec1_001665 Nc1cccc(c1)C2=NCCN2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L16 compound treatment 0.263 -0.00574 -0.31 -0.3086 -1.0 3211052 TimTec1_001666 CNC(=S)Nc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L17 compound treatment 0.289 0.0203 1.09 1.0886 1.0 3083131 TimTec1_001667 Cc1nc2ccc(Cl)cc2n1CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L18 compound treatment 0.322 0.0533 2.86 2.862 1.0 1188527 TimTec1_001668 CN1CCCc2cc(ccc12)c3ccnc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L19 compound treatment 0.276 0.00726 0.39 0.39 1.0 3211053 TimTec1_001669 CC(C)/C=c\1/[nH]c(=O)/c(=C/c2ccccc2)/[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L20 compound treatment 0.392 0.123 6.62 6.6236 1.0 3083134 TimTec1_001670 CCOC(=O)c1sc(NC(=O)C)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L21 compound treatment 0.282 0.0133 0.71 0.7125 1.0 3211054 TimTec1_001671 CC[C@H]1[C@@H]2OC(=O)[C@@H](C)[C@@H]2[C@H]3C[C@@H]([C@@H]4C[C@H](C)C(=O)O4)N5CCCC[C@H]1[C@H]35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L22 compound treatment 0.342 0.0733 3.94 3.9367 1.0 1341798 TimTec1_001672 O=C(Nc1ccccc1)OCC2(C(=O)c3ccccc3C2=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L23 mock treatment 0.269 2.58E-4 0.01 0.0139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 L24 mock treatment 0.26 -0.00874 -0.47 -0.4698 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M01 compound treatment 0.252 -0.0167 -0.9 -0.8997 -1.0 3083213 TimTec1_001673 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc3ccc(O)cc32)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M02 compound treatment 0.294 0.0253 1.36 1.3573 1.0 3211055 TimTec1_001674 Clc1ccc(cc1)C(CC(=O)c2ccc(Br)cc2)C3CCCCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M03 compound treatment 0.284 0.0153 0.82 0.8199 1.0 3083215 TimTec1_001675 COc1ccc2CCC3[C@@](C)(CO)CCC[C@]3(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M04 compound treatment 0.322 0.0533 2.86 2.862 1.0 3211056 TimTec1_001676 COc1cc(/C=N\n2nnnc2N)cc(Cl)c1OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M05 compound treatment 0.258 -0.0107 -0.58 -0.5772 -1.0 1459549 TimTec1_001677 C=CCCN1C[C@@H]2CC(C1)c3cccc(=O)n3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M06 compound treatment 0.272 0.00326 0.18 0.1751 1.0 1091851 TimTec1_001678 CC1=C(SCCO1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M07 compound treatment 0.51 0.241 12.96 12.9647 1.0 3083218 TimTec1_001679 OCn1nc(oc1=S)c2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M08 compound treatment 0.562 0.293 15.76 15.7591 1.0 3211058 TimTec1_001680 CN(C)c1ccc(cc1)N/2CC(=O)S\C2=N\C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M09 compound treatment 0.541 0.272 14.63 14.6306 1.0 1163310 TimTec1_001681 CN(C(=O)CSc1ccccc1C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M10 compound treatment 0.332 0.0633 3.4 3.3994 1.0 1289766 TimTec1_001682 Cc1ccccc1NC(=O)c2c[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M11 compound treatment 0.4 0.131 7.05 7.0535 1.0 3211059 TimTec1_001683 O=C/1ON=C(\C1=C\C=C\c2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M12 compound treatment 0.507 0.238 12.8 12.8035 1.0 1227323 TimTec1_001684 O=C(C1C(c2cccnc2)C(C#N)(C#N)C3C=Cc4ccccc4N13)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M13 compound treatment 0.295 0.0263 1.41 1.4111 1.0 1914043 TimTec1_001685 CCSc1sc(CN(C)C)cc1/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M14 compound treatment 0.345 0.0763 4.1 4.0979 1.0 1340838 TimTec1_001686 CCOC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M15 compound treatment 0.339 0.0703 3.78 3.7755 1.0 1362482 TimTec1_001687 Nc1nonc1NC(=O)CSc2ncccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M16 compound treatment 0.264 -0.00474 -0.25 -0.2548 -1.0 1375046 TimTec1_001688 NNC(=O)CSCc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M17 compound treatment 0.302 0.0333 1.79 1.7872 1.0 1460899 TimTec1_001689 CC(=O)Nc1nonc1N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M18 compound treatment 0.269 2.58E-4 0.01 0.0139 1.0 1065783 TimTec1_001690 CNC(=S)Nc1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M19 compound treatment 0.297 0.0283 1.52 1.5185 1.0 1042406 TimTec1_001691 Clc1ccc(NC(=O)NC2CCCCC2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M20 compound treatment 0.285 0.0163 0.87 0.8737 1.0 1082102 TimTec1_001692 COc1ccc(NC(=S)Nc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M21 compound treatment 0.425 0.156 8.4 8.397 1.0 3211060 TimTec1_001693 CN1C/C(=C\c2ccccc2C)/C(=O)\C(=C\c3ccccc3C)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M22 compound treatment 0.671 0.402 21.62 21.6165 1.0 3083226 TimTec1_001694 O=C(/C(=C\1/NC(=O)c2ccccc2N1)/C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M23 mock treatment 0.291 0.0223 1.2 1.1961 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 M24 mock treatment 0.269 2.58E-4 0.01 0.0139 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N01 compound treatment 0.267 -0.00174 -0.09 -0.0936 -1.0 1397605 TimTec1_001695 Cc1ccc(cc1)N(C2CCS(=O)(=O)C2)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N02 compound treatment 0.283 0.0143 0.77 0.7662 1.0 1024491 TimTec1_001696 COC(=O)c1ccc(=O)oc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N03 compound treatment 0.552 0.283 15.22 15.2217 1.0 3211061 TimTec1_001697 O=C(CCCN1C(=O)S/C(=C/c2ccccc2)/C1=S)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N04 compound treatment 0.342 0.0733 3.94 3.9367 1.0 3083229 TimTec1_001698 Brc1cccc(c1)C(=O)C2=CC3Cc4ccccc4C3C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N05 compound treatment 0.276 0.00726 0.39 0.39 1.0 1440003 TimTec1_001699 CCc1cc(c2n[nH]c(CCC(=O)O)c2c3nc4ccccc4n3C)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N06 compound treatment 0.278 0.00926 0.5 0.4975 1.0 3083231 TimTec1_001700 OC(=O)C1(SCCCS1)C2CCC3OCOC3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N07 compound treatment 0.268 -7.42E-4 -0.04 -0.0399 -1.0 1108575 TimTec1_001701 C[N+](=Cc1ccc(C#N)cc1)[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N08 compound treatment 0.347 0.0783 4.21 4.2054 1.0 1363444 TimTec1_001702 OC(CN1C(=O)c2ccccc2C1=O)CN3CCN(CC3)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N09 compound treatment 0.311 0.0423 2.27 2.2709 1.0 1864240 TimTec1_001703 COc1cc(/C=C(\C#N)/c2ccc(Cl)cc2)ccc1OC(=O)C3COc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N10 compound treatment 0.266 -0.00274 -0.15 -0.1473 -1.0 3082142 TimTec1_001704 CC(=O)O/C(=C\c1cn(C(=O)C)c2ccccc12)/C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N11 compound treatment 0.432 0.163 8.77 8.7731 1.0 1722000 TimTec1_001705 Cc1cccc(c1)N2C(=O)c3sc4nccc(=O)n4c3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N12 compound treatment 0.273 0.00426 0.23 0.2288 1.0 1517994 TimTec1_001706 Cc1c[nH]c2cccc(OCC(O)CN3CCN(CC3)C(c4ccccc4)c5ccccc5)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N13 compound treatment 0.515 0.246 13.23 13.2334 1.0 3082144 TimTec1_001707 Fc1ccc(NC(=O)CSc2nnc3ccccn23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N14 compound treatment 0.362 0.0933 5.01 5.0115 1.0 1606324 TimTec1_001708 CN(C)c1nc2ccc(OCCN3CCOCC3)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N15 compound treatment 0.264 -0.00474 -0.25 -0.2548 -1.0 3082146 TimTec1_001709 CC(CC(=O)O)n1ccnc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N16 compound treatment 0.252 -0.0167 -0.9 -0.8997 -1.0 3211063 TimTec1_001710 CCNC(=S)Nc1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N17 compound treatment 0.325 0.0563 3.02 3.0232 1.0 3082148 TimTec1_001711 C(CSc1nc2ccccc2o1)Sc3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N18 compound treatment 0.263 -0.00574 -0.31 -0.3086 -1.0 1722403 TimTec1_001712 OC(OCC1Cc2ccccc2O1)C3Cc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N19 compound treatment 0.279 0.0103 0.55 0.5512 1.0 3211064 TimTec1_001713 COc1ccc(/C=c/2\[nH]c(=O)\c(=C/c3ccc(OC)cc3)\[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N20 compound treatment 0.566 0.297 15.97 15.974 1.0 1707203 TimTec1_001714 Cc1cccc(Nc2nc3nonc3nc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N21 compound treatment 0.273 0.00426 0.23 0.2288 1.0 3211065 TimTec1_001715 CC(C)(C)C1(O)C=C(O)C(=O)N1c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N22 compound treatment 0.491 0.222 11.94 11.9437 1.0 1565579 TimTec1_001716 O=C(OCCC1(C(=O)c2ccccc2C1=O)c3ccccc3)c4cc5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N23 mock treatment 0.258 -0.0107 -0.58 -0.5772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 N24 mock treatment 0.235 -0.0337 -1.81 -1.8132 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O01 compound treatment 0.589 0.32 17.21 17.21 1.0 3211066 TimTec1_001717 CC1=C(C)C2C(=NC(=NC2=O)c3ccc(o3)c4ccc(cc4)C(=O)O)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O02 compound treatment 0.38 0.111 5.98 5.9788 1.0 3082153 TimTec1_001718 CCOC(=O)c1[nH]c(C)c(CC(C)C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O03 compound treatment 0.439 0.17 9.15 9.1493 1.0 1487341 TimTec1_001719 COc1ccc(NC(c2ccc(C)cc2)n3ncc4c(=O)n(C)c5ccccc5c34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O04 compound treatment 0.467 0.198 10.65 10.654 1.0 3082155 TimTec1_001720 Cc1sc2NC(NC(=O)c2c1C)/C=C/c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O05 compound treatment 0.269 2.58E-4 0.01 0.0139 1.0 3211067 TimTec1_001721 CC[C@H]1CN2CCC3(C2C[C@@H]1/C(=C\OC)/C(=O)OC)C(=O)Nc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O06 compound treatment 0.271 0.00226 0.12 0.1213 1.0 1300191 TimTec1_001722 C(Nc1ncnc2nc[nH]c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O07 compound treatment 0.309 0.0403 2.16 2.1634 1.0 3211068 TimTec1_001723 Cc1nn(c(C)c1/N=C/c2c(O)ccc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O08 compound treatment 0.289 0.0203 1.09 1.0886 1.0 1782754 TimTec1_001724 OC(=O)c1c[nH]c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O09 compound treatment 0.506 0.237 12.75 12.7498 1.0 1165165 TimTec1_001725 C=CCn1nnnc1SCc2cccc(CSc3nnnn3CC=C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O10 compound treatment 0.296 0.0273 1.46 1.4648 1.0 1284834 TimTec1_001726 CCc1ccccc1NC(=O)c2c[nH]c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O11 compound treatment 0.385 0.116 6.25 6.2475 1.0 3209092 TimTec1_001727 OC(=O)c1ccc(N/C=C/2\C(=O)ON=C2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O12 compound treatment 0.277 0.00826 0.44 0.4438 1.0 1145898 TimTec1_001728 Nc1nc2CCCCCc2c(c1C#N)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O13 compound treatment 0.269 2.58E-4 0.01 0.0139 1.0 3209093 TimTec1_001729 Cc1cc(C(=O)O)c(s1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O14 compound treatment 0.335 0.0663 3.56 3.5606 1.0 1667092 TimTec1_001730 COc1ccc(cc1)c2c[nH]c(=N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O15 compound treatment 0.302 0.0333 1.79 1.7872 1.0 1602686 TimTec1_001731 Nc1nonc1NC(=O)CSC2=NCCS2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O16 compound treatment 0.3 0.0313 1.68 1.6797 1.0 1216965 TimTec1_001732 COc1ccc(cc1OC)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O17 compound treatment 0.394 0.125 6.73 6.7311 1.0 3209094 TimTec1_001733 CC(=O)Nc1nonc1Nc2csc(CC#N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O18 compound treatment 0.282 0.0133 0.71 0.7125 1.0 3082865 TimTec1_001734 Cc1cccc(C)c1NS(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O19 compound treatment 0.385 0.116 6.25 6.2475 1.0 3209095 TimTec1_001735 OC(=O)Nc1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O20 compound treatment 0.435 0.166 8.93 8.9344 1.0 3082867 TimTec1_001736 OC(=O)c1ccc(/N=C/c2ccc(o2)c3ccc(Cl)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O21 compound treatment 0.49 0.221 11.89 11.8899 1.0 1913174 TimTec1_001737 CN1C/C(=C\c2ccc3OCOc3c2)/C(=O)\C(=C\c4ccc5OCOc5c4)\C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O22 compound treatment 0.322 0.0533 2.86 2.862 1.0 1594528 TimTec1_001738 NC(=O)c1ccc(OC2CSC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O23 mock treatment 0.27 0.00126 0.07 0.0676 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 O24 mock treatment 0.275 0.00626 0.34 0.3363 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P01 compound treatment 0.268 -7.42E-4 -0.04 -0.0399 -1.0 1562676 TimTec1_001739 S=c1oc(Cc2ccccc2)nn1CN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P02 compound treatment 0.247 -0.0217 -1.17 -1.1684 -1.0 1066227 TimTec1_001740 CC(=O)Nc1nc(C)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P03 compound treatment 0.537 0.268 14.42 14.4156 1.0 3209096 TimTec1_001741 Cc1cc(C(=O)CSc2nnc3ccccn23)c(C)n1c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P04 compound treatment 0.247 -0.0217 -1.17 -1.1684 -1.0 1472764 TimTec1_001742 OCCNC(=O)c1ccc2OCCOCCOCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P05 compound treatment 0.308 0.0393 2.11 2.1096 1.0 1707455 TimTec1_001743 C(N1CCCc2ccccc12)c3cn4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P06 compound treatment 0.329 0.0603 3.24 3.2381 1.0 1631427 TimTec1_001744 COc1ccc2c(CCC3=C(C)C(=O)CCC32C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P07 compound treatment 0.326 0.0573 3.08 3.0769 1.0 1684686 TimTec1_001745 N1C(Nc2cccc3cccc1c23)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P08 compound treatment 0.301 0.0323 1.73 1.7335 1.0 1244779 TimTec1_001746 C(OCc1ccccc1)C(CSc2ccccc2)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P09 compound treatment 0.327 0.0583 3.13 3.1307 1.0 3082946 TimTec1_001747 Clc1ccccc1/C=C/C(=O)Nc2nnc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P10 compound treatment 0.333 0.0643 3.45 3.4531 1.0 3209097 TimTec1_001748 O=C/1OC(=N\C1=C/c2c[nH]c3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P11 compound treatment 0.321 0.0523 2.81 2.8082 1.0 1718471 TimTec1_001749 CCCc1cc(=O)n2c3C(=O)N(Cc4ccccc4)C(=O)c3sc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P12 compound treatment 0.275 0.00626 0.34 0.3363 1.0 1434439 TimTec1_001750 Cc1nccn1CC2CCc3c(C2=O)c4ccccc4n3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P13 compound treatment 0.307 0.0383 2.06 2.0559 1.0 3209098 TimTec1_001751 Cc1nnc(C)n1/N=C/C=C\c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P14 compound treatment 0.297 0.0283 1.52 1.5185 1.0 1284591 TimTec1_001752 CS(=O)(=O)Cc1ccc(Oc2ccc(NS(=O)(=O)C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P15 compound treatment 0.257 -0.0117 -0.63 -0.631 -1.0 1689423 TimTec1_001753 COc1cc-2c(CC3N(C)CCc4c(OC)c(OC)c(OC)c2c34)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P16 compound treatment 0.256 -0.0127 -0.68 -0.6847 -1.0 3082952 TimTec1_001754 CCNC(=S)N1CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P17 compound treatment 0.395 0.126 6.78 6.7848 1.0 1735540 TimTec1_001755 CCCCn1c(=O)oc2cc(Br)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P18 compound treatment 0.588 0.319 17.16 17.1563 1.0 3209099 TimTec1_001756 FC(F)(F)c1cccc(NC(=O)CSc2cccc3cccnc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P19 compound treatment 0.251 -0.0177 -0.95 -0.9534 -1.0 3082954 TimTec1_001757 CCN1CC(=O)N(C1=S)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P20 compound treatment 0.259 -0.00974 -0.52 -0.5235 -1.0 1412266 TimTec1_001758 CC(=O)n1c2ccc(C)cc2c3nc4ccccc4nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P21 compound treatment 0.254 -0.0147 -0.79 -0.7922 -1.0 3209100 TimTec1_001759 Cc1cn(C2CC(NC(=O)C(C)(C)C)C(CO)O2)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P22 compound treatment 0.301 0.0323 1.73 1.7335 1.0 1065752 TimTec1_001760 O=C1C(=Cc2c[nH]c3ccccc23)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P23 mock treatment 0.259 -0.00974 -0.52 -0.5235 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2067 P24 mock treatment 0.258 -0.0107 -0.58 -0.5772 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A01 compound treatment 0.357 0.098 5.27 5.2663 1.0 3082958 TimTec1_001761 O=C1C(=Cc2cccnc2)C(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A02 compound treatment 0.238 -0.021 -1.13 -1.1285 -1.0 3209101 TimTec1_001762 COc1ccc2S/C(=C/3\OC(=S)N(C)C3=O)/N(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A03 compound treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1919999 TimTec1_001763 Cc1cc(Br)c(c(Br)c1)S(=O)(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A04 compound treatment 0.474 0.215 11.55 11.5537 1.0 1199633 TimTec1_001764 NS(=O)(=O)c1ccc(NC(=O)COc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A05 compound treatment 0.281 0.022 1.18 1.1822 1.0 1313236 TimTec1_001765 Cc1ccc(OCC(=O)O)c(c1)c2ccno2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A06 compound treatment 0.295 0.036 1.93 1.9346 1.0 1074315 TimTec1_001766 Cc1ccc(cc1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A07 compound treatment 0.413 0.154 8.28 8.2756 1.0 1096423 TimTec1_001767 COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A08 compound treatment 0.519 0.26 13.97 13.9719 1.0 3209102 TimTec1_001768 Cc1ccc(s1)C(=O)CSCC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A09 compound treatment 0.269 0.01 0.54 0.5374 1.0 1239893 TimTec1_001769 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccccc2)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A10 compound treatment 0.347 0.088 4.73 4.7289 1.0 1315182 TimTec1_001770 Cc1cccc(n1)C2Nc3ccccc3C(=O)N2CCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A11 compound treatment 0.367 0.108 5.8 5.8037 1.0 1522752 TimTec1_001771 COc1ccccc1c2oc3ccccc3c(=O)c2OC(=O)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A12 compound treatment 0.241 -0.018 -0.97 -0.9673 -1.0 1519057 TimTec1_001772 CC(NC(=O)COc1ccccc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A13 compound treatment 0.276 0.017 0.91 0.9135 1.0 3082964 TimTec1_001773 COC(=O)c1sc2nc(C)cc(c2c1N)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A14 compound treatment 0.26 0.001 0.05 0.0537 1.0 1723203 TimTec1_001774 NNC(=O)C(O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A15 compound treatment 0.595 0.336 18.06 18.0559 1.0 3209103 TimTec1_001775 COc1ccc(/C=C\2/SC(=S)NC2=O)cc1COc3ccc(F)cc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A16 compound treatment 0.541 0.282 15.15 15.1541 1.0 1432060 TimTec1_001776 NNC(=O)c1ccc(COc2cc(Cl)ccc2Cl)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A17 compound treatment 0.363 0.104 5.59 5.5887 1.0 1236095 TimTec1_001777 COc1ccc(cc1)c2cc([nH]c(=S)c2C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A18 compound treatment 0.538 0.279 14.99 14.9929 1.0 1129328 TimTec1_001778 COc1ccccc1CCNC(=O)c2ccc(COc3ccccc3Cl)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A19 compound treatment 0.479 0.22 11.82 11.8223 1.0 3083042 TimTec1_001779 Oc1ccc(Br)cc1/C=N/n2cnc3sc4CCCCc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A20 compound treatment 0.508 0.249 13.38 13.3807 1.0 1178649 TimTec1_001780 COc1ccc(NC(=O)c2ccc(CSc3ccccn3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A21 compound treatment 0.544 0.285 15.32 15.3153 1.0 1547489 TimTec1_001781 CCOC(=O)COc1ccc(Br)cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A22 compound treatment 0.264 0.005 0.27 0.2687 1.0 3209104 TimTec1_001782 CC(C)(C)S(=O)(=O)c1ccccc1/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A23 mock treatment 0.287 0.028 1.5 1.5047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 A24 mock treatment 0.24 -0.019 -1.02 -1.021 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B01 compound treatment 0.268 0.009 0.48 0.4836 1.0 3083046 TimTec1_001783 N/C(=N\O)/C(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B02 compound treatment 0.278 0.019 1.02 1.021 1.0 1679359 TimTec1_001784 OC(=O)CCCN1C(=O)CSC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B03 compound treatment 0.338 0.079 4.25 4.2453 1.0 3209105 TimTec1_001785 CC(c1cc(Cl)ccc1[N+]#[C-])S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B04 compound treatment 0.263 0.004 0.21 0.215 1.0 1620877 TimTec1_001786 CC(C)(C)c1nc(C#N)c(o1)N2CCC(CC2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B05 compound treatment 0.355 0.096 5.16 5.1588 1.0 1533552 TimTec1_001787 CC(Oc1ccc(Cl)cc1Cl)C(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B06 compound treatment 0.39 0.131 7.04 7.0397 1.0 3083049 TimTec1_001788 Brc1ccc2C(C#N)C(C=Cc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B07 compound treatment 0.353 0.094 5.05 5.0514 1.0 1606872 TimTec1_001789 CCOC(=O)C1=C(C)N(C(=C(C#N)C1c2ccc(Br)cc2)N)c3nonc3NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B08 compound treatment 0.383 0.124 6.66 6.6635 1.0 3083051 TimTec1_001790 O=C(NC1=SC2=C(CCCC2)C1C#N)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B09 compound treatment 0.266 0.007 0.38 0.3762 1.0 3209106 TimTec1_001791 CCOC(=O)c1c(N)c[nH]c1NCc2ccc(Cl)nc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B10 compound treatment 0.494 0.235 12.63 12.6284 1.0 3209225 TimTec1_001792 Cc1c(/C=C/2\S/C(=N/c3ccccc3)/N(C4CCCC4)C2=O)c5ccccc5n1CC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B11 compound treatment 0.286 0.027 1.45 1.4509 1.0 1450803 TimTec1_001793 CCN(CC)c1nc2ccccc2c(=O)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B12 compound treatment 0.387 0.128 6.88 6.8785 1.0 3083054 TimTec1_001794 COc1ccc(cc1)c2nn(CN3CCOCC3)c(=S)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B13 compound treatment 0.544 0.285 15.32 15.3153 1.0 1437460 TimTec1_001795 Cc1nn(c2SC(=C3C(c12)c4ccccc4OC3=O)N)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B14 compound treatment 0.478 0.219 11.77 11.7686 1.0 1123272 TimTec1_001796 CSc1nc2ccc(cc2s1)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B15 compound treatment 0.598 0.339 18.22 18.2172 1.0 3209226 TimTec1_001797 CC1CS/C(=C(/C(=O)O)\C(=O)/C=C/c2cccc(O)c2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B16 compound treatment 0.55 0.291 15.64 15.6377 1.0 1179029 TimTec1_001798 C(Cn1c(CSc2nc3ccccc3o2)nc4ccccc14)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B17 compound treatment 0.359 0.1 5.37 5.3738 1.0 3209227 TimTec1_001799 OC(=O)C(Cc1c[nH]cn1)NC2CNN=C2c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B18 compound treatment 0.614 0.355 19.08 19.077 1.0 3209228 TimTec1_001800 Cc1ccc(cc1)C2=NNC(S2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B19 compound treatment 0.289 0.03 1.61 1.6121 1.0 1431685 TimTec1_001801 Fc1cccc(Cl)c1c2nc(=S)[nH]c3[nH]c(=S)[nH]c(=S)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B20 compound treatment 0.306 0.047 2.53 2.5257 1.0 1251757 TimTec1_001802 Fc1ccc(CSc2ccccc2C(=O)NC3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B21 compound treatment 0.307 0.048 2.58 2.5794 1.0 3209229 TimTec1_001803 NC(=O)c1c(NC(=S)NC(=O)c2ccccc2Cl)sc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B22 compound treatment 0.589 0.33 17.73 17.7335 1.0 1601676 TimTec1_001804 O=C(COc1ccccc1)Nc2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B23 mock treatment 0.263 0.004 0.21 0.215 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 B24 mock treatment 0.27 0.011 0.59 0.5911 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C01 compound treatment 0.279 0.02 1.07 1.0748 1.0 1124602 TimTec1_001805 CCCC(=O)CC(C1C(=O)c2ccccc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C02 compound treatment 0.277 0.018 0.97 0.9673 1.0 1456543 TimTec1_001806 NC(=S)Nc1ccc(cc1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C03 compound treatment 0.254 -0.005 -0.27 -0.2687 -1.0 3083139 TimTec1_001807 CN(C(=S)SCc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C04 compound treatment 0.291 0.032 1.72 1.7196 1.0 3209230 TimTec1_001808 COc1ccc(cc1)C2NNC(=S)S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C05 compound treatment 0.48 0.221 11.88 11.8761 1.0 1627479 TimTec1_001809 Clc1ccc2occ(c3nc4ccccc4[nH]3)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C06 compound treatment 0.283 0.024 1.29 1.2897 1.0 1585678 TimTec1_001810 CCCC(Nc1cc(Cl)cc(Cl)c1)n2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C07 compound treatment 0.569 0.31 16.66 16.6588 1.0 1693611 TimTec1_001811 COc1cc2ccc(=O)oc2c(O)c1OCC=C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C08 compound treatment 0.47 0.211 11.34 11.3387 1.0 1333990 TimTec1_001812 COc1c2COC(=O)c2c(CSc3nnnn3c4ccccc4)c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C09 compound treatment 0.585 0.326 17.52 17.5186 1.0 1282090 TimTec1_001813 COc1cc2ccc(=O)oc2c(OC(=O)C)c1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C10 compound treatment 0.436 0.177 9.51 9.5116 1.0 1488752 TimTec1_001814 O=C(CSc1nnnn1Cc2ccccc2)Nc3ccccc3Oc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C11 compound treatment 0.485 0.226 12.14 12.1448 1.0 3083144 TimTec1_001815 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C3SCCS3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C12 compound treatment 0.508 0.249 13.38 13.3807 1.0 1118830 TimTec1_001816 CCc1ccc(OCC(=O)Nc2nnc[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C13 compound treatment 0.275 0.016 0.86 0.8598 1.0 1376257 TimTec1_001817 OC(=O)C1CCCCC1C(=O)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C14 compound treatment 0.275 0.016 0.86 0.8598 1.0 1783811 TimTec1_001818 CCCc1cc(=O)nc(SCC(=O)N)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C15 compound treatment 0.261 0.002 0.11 0.1075 1.0 1028427 TimTec1_001819 NC(Cc1ccccc1F)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C16 compound treatment 0.451 0.192 10.32 10.3177 1.0 1545473 TimTec1_001820 COc1ccccc1OCc2ccc(o2)C(=O)NCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C17 compound treatment 0.269 0.01 0.54 0.5374 1.0 3209231 TimTec1_001821 O=C1C2NN=CC2C(=O)N1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C18 compound treatment 0.35 0.091 4.89 4.8901 1.0 1165247 TimTec1_001822 CC1Cc2ccccc2N1C(=O)Nc3ccc(Cl)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C19 compound treatment 0.359 0.1 5.37 5.3738 1.0 1627796 TimTec1_001823 COC(=O)c1ccc(CN2CCN(CC2)c3ccccc3OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C20 compound treatment 0.445 0.186 10.0 9.9953 1.0 1491738 TimTec1_001824 O=C(N1CCOCC1)c2ccc(CSc3ncccn3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C21 compound treatment 0.3 0.041 2.2 2.2033 1.0 3209232 TimTec1_001825 CN(C)c1ccc(/C=C/C(=O)C(=C2SCCS2)C(=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C22 compound treatment 0.273 0.014 0.75 0.7523 1.0 3083151 TimTec1_001826 CCN(CC)S(=O)(=O)c1ccccc1/C=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C23 mock treatment 0.276 0.017 0.91 0.9135 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 C24 mock treatment 0.259 0.0 0.0 -1.0 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D01 compound treatment 0.271 0.012 0.64 0.6449 1.0 3209233 TimTec1_001827 CC(Oc1ccc(C)cc1)n2ccc3CCCCc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D02 compound treatment 0.265 0.006 0.32 0.3224 1.0 1189402 TimTec1_001828 CN(C)CCCN1C(C(=C(O)C1=O)C(=O)c2cccs2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D03 compound treatment 0.275 0.016 0.86 0.8598 1.0 1710381 TimTec1_001829 Cc1ccc(cc1)S(=O)(=O)C(CC=C)c2cc(Cl)ccc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D04 compound treatment 0.391 0.132 7.09 7.0934 1.0 3209234 TimTec1_001830 Cc1ccc2nc(NCc3cccnc3)c(/C=N/Cc4cccnc4)c(=O)n2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D05 compound treatment 0.281 0.022 1.18 1.1822 1.0 1327331 TimTec1_001831 O=C1N(C(=O)c2ccccc12)c3ccc(C#N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D06 compound treatment 0.443 0.184 9.89 9.8878 1.0 1663256 TimTec1_001832 CCc1c(C)sc(NC(=O)c2cccs2)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D07 compound treatment 0.581 0.322 17.3 17.3036 1.0 3209235 TimTec1_001833 CC(=O)/N=C/1\NC(=O)\C(=C\c2ccc(o2)c3ccc4C(=O)OCc4c3)\S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D08 compound treatment 0.424 0.165 8.87 8.8668 1.0 1576966 TimTec1_001834 CCOc1ccc2nc3c(=O)[nH]c(=O)nc3[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D09 compound treatment 0.264 0.005 0.27 0.2687 1.0 3209236 TimTec1_001835 CC1(C)COC(=N1)/C=C(\O)/c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D10 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 3082165 TimTec1_001836 Cc1ccc(cc1)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D11 compound treatment 0.356 0.097 5.21 5.2126 1.0 1734335 TimTec1_001837 Cc1cccc(c1)N2CCN(CC(O)CN3C(=O)c4ccccc4C3=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D12 compound treatment 0.57 0.311 16.71 16.7125 1.0 1573706 TimTec1_001838 Clc1cccc2cccc(c12)S(=O)(=O)Nc3ccc(OCC(=O)N4CCOCC4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D13 compound treatment 0.274 0.015 0.81 0.8061 1.0 1609998 TimTec1_001839 CN(C)CCCn1c(N)c(c2nc3ccccc3[nH]2)c4nc(C#N)c(C#N)nc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D14 compound treatment 0.469 0.21 11.28 11.285 1.0 3082168 TimTec1_001840 Clc1cc(C#N)ccc1CSc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D15 compound treatment 0.332 0.073 3.92 3.9229 1.0 1310660 TimTec1_001841 OC(=O)c1ccc(cc1)C2SCC(=O)N2NS(=O)(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D16 compound treatment 0.338 0.079 4.25 4.2453 1.0 1357681 TimTec1_001842 Nn1c(SCc2ccc(F)c3ccccc23)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D17 compound treatment 0.293 0.034 1.83 1.8271 1.0 3082170 TimTec1_001843 CN(C)c1ccc(cc1)C2=NN(CC2NC(Cc3c[nH]cn3)C(=O)O)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D18 compound treatment 0.308 0.049 2.63 2.6332 1.0 1273745 TimTec1_001844 O=C(N1CCCc2ccccc12)c3ccccc3SCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D19 compound treatment 0.307 0.048 2.58 2.5794 1.0 3209237 TimTec1_001845 COc1cc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2NC(=O)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D20 compound treatment 0.412 0.153 8.22 8.2219 1.0 3082173 TimTec1_001846 CC(O)C(O)C(O)C(O)C1NN=C(S1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D21 compound treatment 0.289 0.03 1.61 1.6121 1.0 3209358 TimTec1_001847 C(Oc1ccccc1)C2CO/C(=N\c3ccccc3)/S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D22 compound treatment 0.328 0.069 3.71 3.7079 1.0 1506008 TimTec1_001848 O=C(COc1ccccc1)N2CCN(CC2)C(=O)COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D23 mock treatment 0.252 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 D24 mock treatment 0.259 0.0 0.0 -1.0 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E01 compound treatment 0.251 -0.008 -0.43 -0.4299 -1.0 1600927 TimTec1_001849 OC(=O)C1CCCN1C(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E02 compound treatment 0.29 0.031 1.67 1.6659 1.0 3209359 TimTec1_001850 CS/C(=N/CC=C)/N1CCN(CC1)\C(=N/CC=C)\SC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E03 compound treatment 0.248 -0.011 -0.59 -0.5911 -1.0 1599515 TimTec1_001851 C(N1CCN(Cc2cccs2)C1c3cccs3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E04 compound treatment 0.284 0.025 1.34 1.3434 1.0 3209360 TimTec1_001852 C=CCc1nc2ccccc2c(=O)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E05 compound treatment 0.372 0.113 6.07 6.0724 1.0 1613532 TimTec1_001853 Oc1ccc(Cl)cc1C(=O)c2cnc-3c(COc4ccccc43)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E06 compound treatment 0.279 0.02 1.07 1.0748 1.0 3082178 TimTec1_001854 N#C/C(=C/c1cccc2ccccc12)/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E07 compound treatment 0.414 0.155 8.33 8.3294 1.0 1314321 TimTec1_001855 COC1C2C=COC2=Nc3c(OC)cccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E08 compound treatment 0.289 0.03 1.61 1.6121 1.0 3082180 TimTec1_001856 CCCCc1cc(CCCC)n2nc(cc2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E09 compound treatment 0.539 0.28 15.05 15.0466 1.0 1232294 TimTec1_001857 COc1cc2OCc3oc4c5CC(Oc5ccc4c(=O)c3-c2cc1OC)C(=C)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E10 compound treatment 0.284 0.025 1.34 1.3434 1.0 1242147 TimTec1_001858 SC1=NN(C2=C(CCC2)S1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E11 compound treatment 0.586 0.327 17.57 17.5723 1.0 1647435 TimTec1_001859 CCSc1nnc(NC(=O)C2CC=CCC2C(=O)O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E12 compound treatment 0.431 0.172 9.24 9.2429 1.0 1075403 TimTec1_001860 OC(=O)CCCSc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E13 compound treatment 0.28 0.021 1.13 1.1285 1.0 3082203 TimTec1_001861 CCOC(=O)c1c(NS(=O)(=O)c2ccc(Br)cc2)sc3CC(C)CCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E14 compound treatment 0.278 0.019 1.02 1.021 1.0 3082205 TimTec1_001862 Cc1ccn(n1)C(=S)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E15 compound treatment 0.265 0.006 0.32 0.3224 1.0 1913414 TimTec1_001863 NC(=O)CSc1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E16 compound treatment 0.55 0.291 15.64 15.6377 1.0 1534949 TimTec1_001864 CC(C)CNC(=O)c1ccc(COc2ccc3ccccc3c2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E17 compound treatment 0.289 0.03 1.61 1.6121 1.0 1920302 TimTec1_001865 Cc1sc2ncnc(SCC(=O)O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E18 compound treatment 0.543 0.284 15.26 15.2616 1.0 1565212 TimTec1_001866 CCN(CC)C(=O)c1ccc(COc2ccccc2Cl)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E19 compound treatment 0.497 0.238 12.79 12.7896 1.0 3082210 TimTec1_001867 CCOc1cccc(/C=C/2\SC(=S)N(CC)C2=O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E20 compound treatment 0.539 0.28 15.05 15.0466 1.0 1608939 TimTec1_001868 O=C(N1CCOCC1)c2ccc(CSc3cccc4cccnc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E21 compound treatment 0.285 0.026 1.4 1.3972 1.0 3082212 TimTec1_001869 Cc1cc(no1)N2C(=O)CCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E22 compound treatment 0.278 0.019 1.02 1.021 1.0 3082214 TimTec1_001870 CN(Cc1ccccc1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E23 mock treatment 0.269 0.01 0.54 0.5374 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 E24 mock treatment 0.254 -0.005 -0.27 -0.2687 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F01 compound treatment 0.374 0.115 6.18 6.1799 1.0 1506581 TimTec1_001871 CCCc1cc(=S)sc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F02 compound treatment 0.291 0.032 1.72 1.7196 1.0 1696777 TimTec1_001872 Cc1c(oc2ccccc12)C(=O)NC3CCS(=O)(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F03 compound treatment 0.272 0.013 0.7 0.6986 1.0 1274289 TimTec1_001873 COc1ccc(NC=O)c(CS(=O)(=O)c2ccc(C)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F04 compound treatment 0.456 0.197 10.59 10.5864 1.0 3209361 TimTec1_001874 CC(C)(C)c1ccc(/C=C/C(=O)NC2CCS(=O)(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F05 compound treatment 0.279 0.02 1.07 1.0748 1.0 3082218 TimTec1_001875 OC(=O)/C=C/C(=O)NN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F06 compound treatment 0.276 0.017 0.91 0.9135 1.0 1130638 TimTec1_001876 CC1(C)Cc2ccccc2-c3nc(SCC(=O)c4ccccc4)n(CC=C)c(=O)c31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F07 compound treatment 0.265 0.006 0.32 0.3224 1.0 1779186 TimTec1_001877 CC(C)COC(=O)C(C)Nc1n[nH]c(=S)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F08 compound treatment 0.623 0.364 19.56 19.5606 1.0 3209362 TimTec1_001878 O=C/1NC(=S)S\C1=C/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F09 compound treatment 0.561 0.302 16.23 16.2288 1.0 3209363 TimTec1_001879 CC(C)(C)c1ccc(/C=C/2\CCCC(=C3SCCCS3)C2=O)c4OCOc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F10 compound treatment 0.287 0.028 1.5 1.5047 1.0 3082222 TimTec1_001880 CN1CC=C2[C@@H](C1)[C@H](c3ccncc3)C(C#N)(C#N)C(=C2C(=O)O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F11 compound treatment 0.383 0.124 6.66 6.6635 1.0 1653015 TimTec1_001881 OC12OCCN(C2=CC(=O)c3ccccc31)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F12 compound treatment 0.278 0.019 1.02 1.021 1.0 3082224 TimTec1_001882 Cn1cnnc1SCc2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F13 compound treatment 0.371 0.112 6.02 6.0186 1.0 3209364 TimTec1_001883 Cc1ccc(cc1)C(=O)OC2CSC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F14 compound treatment 0.448 0.189 10.16 10.1565 1.0 1312775 TimTec1_001884 COc1cc(NC(=O)c2ccc(CSC3CCCCC3)cc2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F15 compound treatment 0.517 0.258 13.86 13.8644 1.0 3082227 TimTec1_001885 Fc1ccc(cc1Cl)C2=NNC3(C2)C(=O)Nc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F16 compound treatment 0.275 0.016 0.86 0.8598 1.0 1110868 TimTec1_001886 CC(C)(Oc1ccc(Br)cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F17 compound treatment 0.278 0.019 1.02 1.021 1.0 3209365 TimTec1_001887 CCCC(=O)c1ccc2=Sc3ccccc3N(=c2c1)CCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F18 compound treatment 0.414 0.155 8.33 8.3294 1.0 3082260 TimTec1_001888 O=C(NCCOc1ccccc1c2ccccc2)c3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F19 compound treatment 0.348 0.089 4.78 4.7827 1.0 3082232 TimTec1_001889 CCSc1nnc([nH]1)c2c(Cl)c(CC)nn2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F20 compound treatment 0.531 0.272 14.62 14.6167 1.0 3082235 TimTec1_001890 Fc1ccc(cc1)C(=O)CCCSc2nc3ccc(Cl)cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F21 compound treatment 0.395 0.136 7.31 7.3084 1.0 1676324 TimTec1_001891 CC1=Nc2ccccc2N(CC(O)Cn3c4ccccc4c5ccccc35)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F22 compound treatment 0.304 0.045 2.42 2.4182 1.0 3082237 TimTec1_001892 CSc1nc2CCCCCc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F23 mock treatment 0.261 0.002 0.11 0.1075 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 F24 mock treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G01 compound treatment 0.591 0.332 17.84 17.841 1.0 3082238 TimTec1_001893 NC(=O)CSc1nc(ccc1C#N)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G02 compound treatment 0.586 0.327 17.57 17.5723 1.0 3209366 TimTec1_001894 Ic1ccc(/C=C/2\SC(=N)NC2=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G03 compound treatment 0.273 0.014 0.75 0.7523 1.0 3082240 TimTec1_001895 CN(Cc1cccs1)C(=S)SCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G04 compound treatment 0.246 -0.013 -0.7 -0.6986 -1.0 3209367 TimTec1_001896 NC(=O)Cn1nnc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G05 compound treatment 0.259 0.0 0.0 -1.0 -1.0 3209368 TimTec1_001897 OC(=O)c1ccccc1c2ccc(/C=N/N3C(=O)C4C5CC(C=C5)C4C3=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G06 compound treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1473623 TimTec1_001898 CCCCC1(CC(=O)N2CCOCC2)C(=O)N(N(C1=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G07 compound treatment 0.379 0.12 6.45 6.4485 1.0 3209369 TimTec1_001899 COC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G08 compound treatment 0.275 0.016 0.86 0.8598 1.0 1265525 TimTec1_001900 Cc1cc(=O)n2nc(nc2[nH]1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G09 compound treatment 0.255 -0.004 -0.21 -0.215 -1.0 3209370 TimTec1_001901 CC(C)C(O)(C(C)O)C(=O)OC[C@@H]1CCN2CCC[C@@H]12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G10 compound treatment 0.297 0.038 2.04 2.042 1.0 3082244 TimTec1_001902 Sc1nnc(Cc2cccc3ccccc23)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G11 compound treatment 0.349 0.09 4.84 4.8364 1.0 3209371 TimTec1_001903 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3nc4ccc(Br)cc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G12 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 1779185 TimTec1_001904 CC(C)OC(=O)C(C)Nc1n[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G13 compound treatment 0.318 0.059 3.17 3.1705 1.0 3082246 TimTec1_001905 Cc1cc(C)n(n1)C(=O)CSc2nc(C)c(C)cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G14 compound treatment 0.293 0.034 1.83 1.8271 1.0 1137282 TimTec1_001906 O=C(Nc1ccccc1)c2ccn(n2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G15 compound treatment 0.287 0.028 1.5 1.5047 1.0 3209372 TimTec1_001907 Cc1cc(NC(=O)C(F)(F)F)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G16 compound treatment 0.467 0.208 11.18 11.1775 1.0 1200660 TimTec1_001908 CN(C1CCCCC1)C(=O)c2ccc(COc3ccc(C)c(C)c3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G17 compound treatment 0.559 0.3 16.12 16.1214 1.0 1113186 TimTec1_001909 Brc1ccc2noc(c3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G18 compound treatment 0.536 0.277 14.89 14.8854 1.0 1294501 TimTec1_001910 CN(C(=O)c1ccc(COc2ccccc2Cl)o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G19 compound treatment 0.259 0.0 0.0 -1.0 -1.0 3209491 TimTec1_001911 COC(=O)C1=CO[C@H](C)[C@@H]2CN3CCC4(C3C[C@@H]21)C(=O)Nc5ccccc54 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G20 compound treatment 0.436 0.177 9.51 9.5116 1.0 1332425 TimTec1_001912 Cc1nnc(SCc2ccc(cc2)C(=O)N3CCOCC3)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G21 compound treatment 0.258 -0.001 -0.05 -0.0537 -1.0 1920052 TimTec1_001913 OC(=O)/C=C/C(=O)NCc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G22 compound treatment 0.258 -0.001 -0.05 -0.0537 -1.0 1403707 TimTec1_001914 CC(C)(C)S(=O)(=O)c1cccc(c1)S(=O)(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G23 mock treatment 0.269 0.01 0.54 0.5374 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 G24 mock treatment 0.252 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H01 compound treatment 0.263 0.004 0.21 0.215 1.0 3209492 TimTec1_001915 CCOC(C)n1cccc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H02 compound treatment 0.32 0.061 3.28 3.278 1.0 1257360 TimTec1_001916 CC(C)Cc1nc(C#N)c(NCC=C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H03 compound treatment 0.51 0.251 13.49 13.4882 1.0 1616013 TimTec1_001917 Cc1ccc(cc1)S(=O)(=O)c2n[nH]c3ccc(Cl)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H04 compound treatment 0.278 0.019 1.02 1.021 1.0 1492803 TimTec1_001918 CC(C)OC(=O)C1=C(C)NC(=O)NC1C2CCC=CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H05 compound treatment 0.317 0.058 3.12 3.1168 1.0 3082254 TimTec1_001919 NC(=N)NS(=O)(=O)c1ccc(NC(=O)/C=C/C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H06 compound treatment 0.286 0.027 1.45 1.4509 1.0 3209493 TimTec1_001920 FC(F)(F)c1cccc(NC(=O)Cn2ccc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H07 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 3082255 TimTec1_001921 CSc1nnc(C)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H08 compound treatment 0.34 0.081 4.35 4.3528 1.0 1174278 TimTec1_001922 COc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H09 compound treatment 0.264 0.005 0.27 0.2687 1.0 1288259 TimTec1_001923 Cn1nc(CC(=O)NN)c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H10 compound treatment 0.293 0.034 1.83 1.8271 1.0 1396336 TimTec1_001924 COc1ccc(Cl)cc1C(=O)N2CCCC2C(=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H11 compound treatment 0.571 0.312 16.77 16.7662 1.0 1259025 TimTec1_001925 COc1ccc(cc1)c2cc(nc(NC(=S)N)n2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H12 compound treatment 0.318 0.059 3.17 3.1705 1.0 3209494 TimTec1_001926 CSc1ccccc1C(=O)NCCOc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H13 compound treatment 0.307 0.048 2.58 2.5794 1.0 3082265 TimTec1_001927 O=C(OC1CSC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H14 compound treatment 0.266 0.007 0.38 0.3762 1.0 1610378 TimTec1_001928 CCS(=O)(=O)Nc1ccc(Br)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H15 compound treatment 0.391 0.132 7.09 7.0934 1.0 1433512 TimTec1_001929 COc1ccc2cc(C3SC(C)C(=O)N3C4CCCO4)c(Cl)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H16 compound treatment 0.276 0.017 0.91 0.9135 1.0 1347404 TimTec1_001930 CN1C(=O)N(C)C(=O)C(CCc2ccncc2)(C1=O)C3(CCCCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H17 compound treatment 0.548 0.289 15.53 15.5303 1.0 1631720 TimTec1_001931 Cc1ccc(cc1)C2C=C(NC(=O)C2C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H18 compound treatment 0.448 0.189 10.16 10.1565 1.0 3082269 TimTec1_001932 CS(=O)(=O)c1nc(n[nH]1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H19 compound treatment 0.253 -0.006 -0.32 -0.3224 -1.0 1458072 TimTec1_001933 C1OC(OCc2nonc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H20 compound treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1288232 TimTec1_001934 CC(=C)CC(N)(CC(=C)C)c1ccncc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H21 compound treatment 0.275 0.016 0.86 0.8598 1.0 1301124 TimTec1_001935 CSc1nsc(SC)c1NC(=O)OCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H22 compound treatment 0.54 0.281 15.1 15.1004 1.0 3209495 TimTec1_001936 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)/C=C/c3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H23 mock treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 H24 mock treatment 0.246 -0.013 -0.7 -0.6986 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I01 compound treatment 0.267 0.008 0.43 0.4299 1.0 1268779 TimTec1_001937 Cc1ccc2c(N)c(sc2n1)C(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I02 compound treatment 0.421 0.162 8.71 8.7055 1.0 3209496 TimTec1_001938 Nc1sc(=S)n(c1c2nc3ccccc3s2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I03 compound treatment 0.251 -0.008 -0.43 -0.4299 -1.0 1735247 TimTec1_001939 Cc1ccc(cc1)N(c2ccc(C)cc2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I04 compound treatment 0.316 0.057 3.06 3.0631 1.0 1463202 TimTec1_001940 S=c1oc2ccccc2n1Cn3c(=S)oc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I05 compound treatment 0.26 0.001 0.05 0.0537 1.0 1128826 TimTec1_001941 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)O)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I06 compound treatment 0.52 0.261 14.03 14.0256 1.0 1310569 TimTec1_001942 O=C(CSc1nc2ccccc2nc1SCC(=O)N3CCCCC3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I07 compound treatment 0.282 0.023 1.24 1.236 1.0 1383182 TimTec1_001943 COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I08 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 1574289 TimTec1_001944 CC(C)(C)NC(=O)CSc1nc2ccccc2nc1SCC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I09 compound treatment 0.267 0.008 0.43 0.4299 1.0 3209497 TimTec1_001945 COC(C)C(O)(C(C)C)C(=O)OC1=CCN2CC[C@H](O)[C@H]21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I10 compound treatment 0.356 0.097 5.21 5.2126 1.0 1160311 TimTec1_001946 Cc1ccc(o1)C(=O)CSC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I11 compound treatment 0.285 0.026 1.4 1.3972 1.0 1681019 TimTec1_001947 S=C(NC1CCCCC1)N2CCN(Cc3ccc4OCOc4c3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I12 compound treatment 0.289 0.03 1.61 1.6121 1.0 1315095 TimTec1_001948 Cc1nnc(NCCc2ccccc2)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I13 compound treatment 0.3 0.041 2.2 2.2033 1.0 3209498 TimTec1_001949 CC1CCc2c(C#N)c(NC(=O)c3cc4nc(cc(n4n3)C(F)(F)F)c5ccccc5)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I14 compound treatment 0.329 0.07 3.76 3.7617 1.0 1544670 TimTec1_001950 CCOc1ccc(cc1)c2nc3ccc(Br)cc3c(C(=O)O)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I15 compound treatment 0.457 0.198 10.64 10.6401 1.0 3209499 TimTec1_001951 Oc1ccc(cc1)c2nc3sc(nc3s2)c4ccc(O)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I16 compound treatment 0.596 0.337 18.11 18.1097 1.0 1375855 TimTec1_001952 Clc1ccc(Cl)c(OCc2ccc(o2)C(=O)NC3CCCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I17 compound treatment 0.311 0.052 2.79 2.7944 1.0 1710780 TimTec1_001953 Cc1ccc(cc1)C(=O)OCC2OC3C(Oc4c(C)c(=O)ncn34)C2OC(=O)c5ccc(C)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I18 compound treatment 0.484 0.225 12.09 12.091 1.0 1488850 TimTec1_001954 CC(C)c1ccc(OCc2ccc(o2)C(=O)N(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I19 compound treatment 0.293 0.034 1.83 1.8271 1.0 3082282 TimTec1_001955 c1ccc(cc1)c2ccnc(c2)c3cc(ccn3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I20 compound treatment 0.361 0.102 5.48 5.4813 1.0 3209500 TimTec1_001956 O=S(=O)(c1ccsc1)c2ccsc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I21 compound treatment 0.378 0.119 6.39 6.3948 1.0 1577514 TimTec1_001957 CC1Oc2ccccc2C(=O)N1c3ccc(OC=C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I22 compound treatment 0.262 0.003 0.16 0.1612 1.0 1686206 TimTec1_001958 CC(C)(C)S(=O)(=O)c1ccc(cc1)S(=O)(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I23 mock treatment 0.272 0.013 0.7 0.6986 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 I24 mock treatment 0.25 -0.009 -0.48 -0.4836 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J01 compound treatment 0.256 -0.003 -0.16 -0.1612 -1.0 3082285 TimTec1_001959 CC(C)OC(C)n1cccc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J02 compound treatment 0.488 0.229 12.31 12.306 1.0 1308224 TimTec1_001960 Cc1c(oc2ccccc12)C(=O)Nc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J03 compound treatment 0.321 0.062 3.33 3.3318 1.0 1495070 TimTec1_001961 COc1ccccc1NCC(=O)n2nc(cc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J04 compound treatment 0.544 0.285 15.32 15.3153 1.0 3209501 TimTec1_001962 Cc1ccc(cc1)S(=O)(=O)/C(=C/C2=Cc3ccccc3OC2)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J05 compound treatment 0.607 0.348 18.7 18.7008 1.0 3082288 TimTec1_001963 Oc1cccc(/C=N/c2ccccc2C#N)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J06 compound treatment 0.287 0.028 1.5 1.5047 1.0 1558299 TimTec1_001964 CCOc1ccc(NC(=O)CN2CCCc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J07 compound treatment 0.272 0.013 0.7 0.6986 1.0 1170983 TimTec1_001965 COC(=O)C(NC(=O)Nc1ccccc1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J08 compound treatment 0.34 0.081 4.35 4.3528 1.0 1183270 TimTec1_001966 CC(C)CC(=O)Nc1cccc(c1)c2nc3cc(C)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J09 compound treatment 0.265 0.006 0.32 0.3224 1.0 1047437 TimTec1_001967 CC(C(=O)O)(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J10 compound treatment 0.268 0.009 0.48 0.4836 1.0 3209502 TimTec1_001968 CN1C(=O)/C(=C(/C#N)\C(=O)N)/c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J11 compound treatment 0.27 0.011 0.59 0.5911 1.0 3082292 TimTec1_001969 CC1(O)CCOCC1NC(Cc2cc3ccccc3[nH]2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J12 compound treatment 0.275 0.016 0.86 0.8598 1.0 3209503 TimTec1_001970 CN1C(=O)C2C=CC=CC2N=C1SCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J13 compound treatment 0.263 0.004 0.21 0.215 1.0 1534000 TimTec1_001971 O=C(c1nnn2CC(=O)OC3(CCCCC3)c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J14 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 3082295 TimTec1_001972 O=C(CSCc1ccccc1)Nc2ccccc2C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J15 compound treatment 0.263 0.004 0.21 0.215 1.0 3209618 TimTec1_001973 OC(=O)CC(S/C(=N/C1CCCC=C1)/N2CCCCC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J16 compound treatment 0.351 0.092 4.94 4.9439 1.0 3209619 TimTec1_001974 CC(C)CCCN1C(=O)NC(=O)/C(=C\c2ccc[nH]2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J17 compound treatment 0.26 0.001 0.05 0.0537 1.0 3082297 TimTec1_001975 O=C(N/C(=C\c1cccnc1)/C(=O)N2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J18 compound treatment 0.274 0.015 0.81 0.8061 1.0 1185980 TimTec1_001976 COc1cc(CNC(=O)c2ccccc2SC)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J19 compound treatment 0.539 0.28 15.05 15.0466 1.0 3082299 TimTec1_001977 c1coc(c1)c2cc(on2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J20 compound treatment 0.312 0.053 2.85 2.8481 1.0 3209620 TimTec1_001978 FC(F)(F)C(=O)Nc1sc2CCCCc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J21 compound treatment 0.29 0.031 1.67 1.6659 1.0 1168141 TimTec1_001979 Cc1cc(C)c(C#N)c(SCCN2CCCCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J22 compound treatment 0.289 0.03 1.61 1.6121 1.0 1235345 TimTec1_001980 O=C(NCCC1=CCCCC1)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J23 mock treatment 0.27 0.011 0.59 0.5911 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 J24 mock treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K01 compound treatment 0.516 0.257 13.81 13.8106 1.0 3209621 TimTec1_001981 Cc1nc2ccc(cc2n1CCc3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K02 compound treatment 0.584 0.325 17.46 17.4648 1.0 3082327 TimTec1_001982 Cc1ccc2nc(NC(=O)OC(C)(C)C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K03 compound treatment 0.252 -0.007 -0.38 -0.3762 -1.0 1449100 TimTec1_001983 C[N+]1(Cc2ccccc2)CCCC1c3ccc(N)nc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K04 compound treatment 0.248 -0.011 -0.59 -0.5911 -1.0 3082329 TimTec1_001984 CC(=O)On1cc(F)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K05 compound treatment 0.293 0.034 1.83 1.8271 1.0 1405621 TimTec1_001985 Cc1cc2ccc(=O)oc2cc1OC[C@@H](O)C(C)(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K06 compound treatment 0.255 -0.004 -0.21 -0.215 -1.0 3082331 TimTec1_001986 Cn1c(S)ncc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K07 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 1398791 TimTec1_001987 CNCC(O)c1cccc(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K08 compound treatment 0.353 0.094 5.05 5.0514 1.0 3209623 TimTec1_001988 COc1ccc(cc1)C2NN(CN3CCOCC3)C(=S)N2Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K09 compound treatment 0.286 0.027 1.45 1.4509 1.0 1115322 TimTec1_001989 COc1ccn(C)c(=O)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K10 compound treatment 0.272 0.013 0.7 0.6986 1.0 3082334 TimTec1_001990 CC1=C(C)N(N=C(S)S1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K11 compound treatment 0.313 0.054 2.9 2.9018 1.0 3209624 TimTec1_001991 O=C(C1CCCO1)N2CCN(C/C=C/c3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K12 compound treatment 0.257 -0.002 -0.11 -0.1075 -1.0 3082336 TimTec1_001992 CN(C)CCNc1nc(=O)[nH]nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K13 compound treatment 0.413 0.154 8.28 8.2756 1.0 1514990 TimTec1_001993 Clc1ccc(cc1)C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K14 compound treatment 0.283 0.024 1.29 1.2897 1.0 3082338 TimTec1_001994 O/C=C\1/C(=O)NC(=O)N(C1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K15 compound treatment 0.337 0.078 4.19 4.1916 1.0 1598606 TimTec1_001995 CC(=O)Nc1nonc1NC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K16 compound treatment 0.473 0.214 11.5 11.4999 1.0 1221200 TimTec1_001996 CC(C)CNC(=O)c1ccc(COc2cc(Cl)ccc2Cl)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K17 compound treatment 0.322 0.063 3.39 3.3855 1.0 3209625 TimTec1_001997 CC(=O)OCC(=O)Nc1cc(Cl)cc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K18 compound treatment 0.317 0.058 3.12 3.1168 1.0 1148960 TimTec1_001998 CCc1ccc(cc1)c2cc(C(=O)OC)c3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K19 compound treatment 0.274 0.015 0.81 0.8061 1.0 3209626 TimTec1_001999 O=C(ON1C(=O)CCC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K20 compound treatment 0.333 0.074 3.98 3.9766 1.0 3082343 TimTec1_002000 CCOC(=O)CSc1nc(C)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K21 compound treatment 0.274 0.015 0.81 0.8061 1.0 3209627 TimTec1_002001 CC(NC(C(=O)O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K22 compound treatment 0.269 0.01 0.54 0.5374 1.0 1544248 TimTec1_002002 COc1cccc(NC(=O)COC(=O)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K23 mock treatment 0.276 0.017 0.91 0.9135 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 K24 mock treatment 0.252 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L01 compound treatment 0.255 -0.004 -0.21 -0.215 -1.0 3209628 TimTec1_002003 CC(C)(O)/C(=C/C#N)/n1cccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L02 compound treatment 0.331 0.072 3.87 3.8691 1.0 3209629 TimTec1_002004 COc1ccc(OCC(=O)Sc2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L03 compound treatment 0.45 0.191 10.26 10.2639 1.0 3082347 TimTec1_002005 O=C(/C=C/c1ccccc1)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L04 compound treatment 0.38 0.121 6.5 6.5023 1.0 1118669 TimTec1_002006 COc1cccc(c1)C(CC(=O)c2ccc(Cl)cc2)C(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L05 compound treatment 0.278 0.019 1.02 1.021 1.0 3082349 TimTec1_002007 CC(C)OC(=O)C(C)/N=C/c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L06 compound treatment 0.276 0.017 0.91 0.9135 1.0 3209630 TimTec1_002008 Clc1ccc(SC(CC(=O)C2CC2)c3ccc(Cl)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L07 compound treatment 0.434 0.175 9.4 9.4041 1.0 1021708 TimTec1_002009 c1ccc(cc1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L08 compound treatment 0.381 0.122 6.56 6.556 1.0 3209631 TimTec1_002010 COC(=O)c1c(N/C=C/2\C(=O)NC(=O)N(Cc3ccccc3)C2=O)sc4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L09 compound treatment 0.495 0.236 12.68 12.6821 1.0 1168270 TimTec1_002011 CCN(CC)c1ncn(Cc2c(Cl)cccc2Cl)c3ncnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L10 compound treatment 0.501 0.242 13.0 13.0046 1.0 3209632 TimTec1_002012 COc1ccccc1OCCNC(=O)c2ccc(cc2)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L11 compound treatment 0.265 0.006 0.32 0.3224 1.0 3082356 TimTec1_002013 OCC/N=C(/N1CCN(CC1)\C(=N\CCO)\c2ccc(Cl)cc2)\c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L12 compound treatment 0.479 0.22 11.82 11.8223 1.0 1733839 TimTec1_002014 Cn1c(SCc2ccoc2C(=O)O)nnc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L13 compound treatment 0.288 0.029 1.56 1.5584 1.0 1368186 TimTec1_002015 NC(=O)CC(=O)c1c(O)c2ccccc2n(c3ccccc3)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L14 compound treatment 0.295 0.036 1.93 1.9346 1.0 3082357 TimTec1_002016 Fc1ccccc1OCCNC(=O)c2ccccc2Nc3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L15 compound treatment 0.287 0.028 1.5 1.5047 1.0 3209633 TimTec1_002017 NC(=O)/C(=C/c1ccc(Cl)cc1)/NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L16 compound treatment 0.369 0.11 5.91 5.9112 1.0 1533648 TimTec1_002018 CC(NC(=O)CSc1nn(c2ccccc2)c(=S)s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L17 compound treatment 0.596 0.337 18.11 18.1097 1.0 3082358 TimTec1_002019 Oc1ccc(/C=C\2/NC(=S)Nc3[nH]\c(=N\c4ccccc4)\sc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L18 compound treatment 0.361 0.102 5.48 5.4813 1.0 3209634 TimTec1_002020 CN1C(=O)C2C=CC=CC2N=C1SCc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L19 compound treatment 0.281 0.022 1.18 1.1822 1.0 3082359 TimTec1_002021 CN(C)c1ccc(cc1)n2c(C)cc(/C=N/c3ccc(O)c(c3)C(=O)O)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L20 compound treatment 0.282 0.023 1.24 1.236 1.0 3209635 TimTec1_002022 OC(=O)/C=C/C(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L21 compound treatment 0.283 0.024 1.29 1.2897 1.0 3082361 TimTec1_002023 Fc1ccc(/C=c\2/sc3=NCCn3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L22 compound treatment 0.581 0.322 17.3 17.3036 1.0 1356390 TimTec1_002024 Cc1ccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L23 mock treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 L24 mock treatment 0.245 -0.014 -0.75 -0.7523 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M01 compound treatment 0.245 -0.014 -0.75 -0.7523 -1.0 1265733 TimTec1_002025 CCOC(=O)c1c(C)c(sc1N)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M02 compound treatment 0.549 0.29 15.58 15.584 1.0 3209636 TimTec1_002026 Oc1ccc(/C=C/2\SC(=N)NC2=O)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M03 compound treatment 0.293 0.034 1.83 1.8271 1.0 3082390 TimTec1_002027 Cc1ccc(NC(=O)OC(C)(C)C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M04 compound treatment 0.26 0.001 0.05 0.0537 1.0 3209637 TimTec1_002028 COc1ccc(CC(=O)N2N=C(C)CC2(O)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M05 compound treatment 0.224 -0.035 -1.88 -1.8808 -1.0 3082392 TimTec1_002029 CC(=CCc1c(O)cc(O)c2C(=O)C[C@H](Oc12)c3ccccc3)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M06 compound treatment 0.344 0.085 4.57 4.5677 1.0 3209638 TimTec1_002030 CN(C)C(=O)CSc1nnc(o1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M07 compound treatment 0.255 -0.004 -0.21 -0.215 -1.0 1286462 TimTec1_002031 CN1C2N=CN(CCCO)C2C(=O)N(C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M08 compound treatment 0.429 0.17 9.14 9.1354 1.0 1699709 TimTec1_002032 COc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3C)c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M09 compound treatment 0.266 0.007 0.38 0.3762 1.0 1409515 TimTec1_002033 CC(=O)Oc1ccn(C)c(=O)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M10 compound treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1211785 TimTec1_002034 CC1(C)Oc2ccc(NC(=O)C3(CCCC3)c4ccccc4)cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M11 compound treatment 0.324 0.065 3.49 3.493 1.0 1344646 TimTec1_002035 Cc1occc1C(=O)Nc2ccc(F)c(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M12 compound treatment 0.326 0.067 3.6 3.6004 1.0 1915457 TimTec1_002036 O=c1[nH]nc(SCc2ccccc2)c(=S)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M13 compound treatment 0.268 0.009 0.48 0.4836 1.0 1068232 TimTec1_002037 COC(=O)Nc1c(C)cc(C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M14 compound treatment 0.268 0.009 0.48 0.4836 1.0 1147050 TimTec1_002038 Clc1ccc(OCc2ccc(o2)C(=O)NC3CCOC3=O)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M15 compound treatment 0.369 0.11 5.91 5.9112 1.0 1216899 TimTec1_002039 Clc1ccccc1C(=O)c2cc(Br)ccc2NC(=O)CSC3=NCCS3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M16 compound treatment 0.444 0.185 9.94 9.9415 1.0 1413128 TimTec1_002040 CCCc1ccc(OCc2ccc(o2)C(=O)NCc3cccnc3)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M17 compound treatment 0.269 0.01 0.54 0.5374 1.0 3082399 TimTec1_002041 CC(=O)OCC(=O)Nc1ccccc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M18 compound treatment 0.488 0.229 12.31 12.306 1.0 1538207 TimTec1_002042 O=C(COC(=O)c1c2CCCCc2nc3ccccc13)Nc4nc5ccccc5s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M19 compound treatment 0.565 0.306 16.44 16.4438 1.0 1322184 TimTec1_002043 CCOc1ccc2nc(SCc3nc4ccccc4[nH]3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M20 compound treatment 0.367 0.108 5.8 5.8037 1.0 3209758 TimTec1_002044 CN(Cc1cccs1)C(=S)SCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M21 compound treatment 0.267 0.008 0.43 0.4299 1.0 1690142 TimTec1_002045 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M22 compound treatment 0.449 0.19 10.21 10.2102 1.0 3082402 TimTec1_002046 CC(=O)OCC(=O)Nc1cccc(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M23 mock treatment 0.272 0.013 0.7 0.6986 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 M24 mock treatment 0.263 0.004 0.21 0.215 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N01 compound treatment 0.339 0.08 4.3 4.299 1.0 3209759 TimTec1_002047 Nc1nc(cc(=S)s1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N02 compound treatment 0.325 0.066 3.55 3.5467 1.0 1028245 TimTec1_002048 Clc1ccc(SC(=O)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N03 compound treatment 0.295 0.036 1.93 1.9346 1.0 1713032 TimTec1_002049 COC(=O)c1ccccc1NC(=O)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N04 compound treatment 0.304 0.045 2.42 2.4182 1.0 3083578 TimTec1_002050 Brc1ccc(cc1)C(C#N)C(CC#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N05 compound treatment 0.274 0.015 0.81 0.8061 1.0 3209760 TimTec1_002051 OC(=O)/C=C/C(=O)N1CCN(CC1)C(=O)\C=C\C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N06 compound treatment 0.533 0.274 14.72 14.7242 1.0 3209761 TimTec1_002052 CCc1ccc(/C=C/2\CN(C)C/C(=C\c3ccc(CC)cc3)/C2O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N07 compound treatment 0.283 0.024 1.29 1.2897 1.0 1389451 TimTec1_002053 Nc1ccc2c(c1)nc(c3ccccc3)c4cc(N)ccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N08 compound treatment 0.347 0.088 4.73 4.7289 1.0 3209762 TimTec1_002054 Fc1ccc(cc1)N2C(=O)NC(=O)/C(=C\Nc3ccccc3)/C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N09 compound treatment 0.373 0.114 6.13 6.1261 1.0 1139527 TimTec1_002055 OC(=O)c1ccc(cc1)N2Cc3ccc(Br)cc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N10 compound treatment 0.27 0.011 0.59 0.5911 1.0 1168036 TimTec1_002056 Cn1c(=S)n(CN2CCC3(CC2)OCCO3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N11 compound treatment 0.298 0.039 2.1 2.0958 1.0 1535531 TimTec1_002057 COC1CC2C(C(OC2=O)C(=O)O)C(OC)C1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N12 compound treatment 0.255 -0.004 -0.21 -0.215 -1.0 1408618 TimTec1_002058 CCS(=O)(=O)N(CC(=O)O)c1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N13 compound treatment 0.318 0.059 3.17 3.1705 1.0 1306524 TimTec1_002059 CCOC(=O)CSC1C(=O)Nc2ccccc2N=C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N14 compound treatment 0.305 0.046 2.47 2.4719 1.0 1728948 TimTec1_002060 CCOC(=O)NC1c2ccccc2Sc3ccc(Cl)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N15 compound treatment 0.38 0.121 6.5 6.5023 1.0 1597862 TimTec1_002061 Oc1ccc(=O)n(CNc2nccs2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N16 compound treatment 0.379 0.12 6.45 6.4485 1.0 3209763 TimTec1_002062 COc1ccc(cc1)c2n[nH]c(SCC(=O)N(C3CCCCC3)C4CCCCC4)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N17 compound treatment 0.392 0.133 7.15 7.1471 1.0 3209764 TimTec1_002063 Cc1ccc(cc1)C2=CC(SC(=N)N2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N18 compound treatment 0.279 0.02 1.07 1.0748 1.0 3083579 TimTec1_002064 Fc1ccc(CSc2ccccc2C(=O)NCc3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N19 compound treatment 0.421 0.162 8.71 8.7055 1.0 3209765 TimTec1_002065 NC1=Nn2c(nnc2SC3(C1C#N)C(=O)Nc4ccccc43)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N20 compound treatment 0.254 -0.005 -0.27 -0.2687 -1.0 1495217 TimTec1_002066 CC(=C)CC1NC2CC(C)(C)C1c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N21 compound treatment 0.274 0.015 0.81 0.8061 1.0 1163918 TimTec1_002067 COc1ccc(c(O)c1)c2nc(N)ncc2c3cscn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N22 compound treatment 0.587 0.328 17.63 17.626 1.0 1657100 TimTec1_002068 CCN(CC)S(=O)(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N23 mock treatment 0.25 -0.009 -0.48 -0.4836 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 N24 mock treatment 0.258 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O01 compound treatment 0.281 0.022 1.18 1.1822 1.0 3083580 TimTec1_002069 OC(=O)[C@@H]1CSC(N1)c2coc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O02 compound treatment 0.297 0.038 2.04 2.042 1.0 3209766 TimTec1_002070 Cc1ccc(cc1)/C(=N\C#N)/NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O03 compound treatment 0.274 0.015 0.81 0.8061 1.0 3083581 TimTec1_002071 CCOC(=O)Nc1ccc(C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O04 compound treatment 0.315 0.056 3.01 3.0093 1.0 3209767 TimTec1_002072 O=C(NCc1ccccc1)/C=C/c2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O05 compound treatment 0.273 0.014 0.75 0.7523 1.0 1190059 TimTec1_002073 CNC1C2CN3CCC(O2)C13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O06 compound treatment 0.394 0.135 7.25 7.2546 1.0 1479488 TimTec1_002074 Cn1c(Sc2cnn(c3ccccc3)c(=O)c2Br)nnc1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O07 compound treatment 0.278 0.019 1.02 1.021 1.0 3487465 TimTec1_002075 OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O08 compound treatment 0.329 0.07 3.76 3.7617 1.0 3083582 TimTec1_002076 CN(C)C(=O)CSc1nnc(c2cccc(F)c2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O09 compound treatment 0.279 0.02 1.07 1.0748 1.0 1278782 TimTec1_002077 COc1ccc2c3CCN4CC5C(C)OC=C(OC(=O)C)[C@H]5C[C@H]4c3[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O10 compound treatment 0.435 0.176 9.46 9.4579 1.0 3083583 TimTec1_002078 O=C(ON1C(=O)CCC1=O)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O11 compound treatment 0.45 0.191 10.26 10.2639 1.0 1523507 TimTec1_002079 NC(=O)c1sc2nc(ccc2c1N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O12 compound treatment 0.348 0.089 4.78 4.7827 1.0 3083584 TimTec1_002080 CCOC(=O)c1cnc2cccc[n+]2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O13 compound treatment 0.325 0.066 3.55 3.5467 1.0 1224089 TimTec1_002081 O=C(Nc1cccc(NC(=O)C2CC2)c1)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O14 compound treatment 0.312 0.053 2.85 2.8481 1.0 3083585 TimTec1_002082 Fc1c(F)c(F)c(OCc2ccc(o2)C(=O)N3CCOCC3)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O15 compound treatment 0.516 0.257 13.81 13.8106 1.0 1612278 TimTec1_002083 CC(=O)Nc1nonc1NC(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O16 compound treatment 0.411 0.152 8.17 8.1682 1.0 1443254 TimTec1_002084 Clc1ccc(OCc2ccc(o2)C(=O)NCc3cccc(Cl)c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O17 compound treatment 0.276 0.017 0.91 0.9135 1.0 1195533 TimTec1_002085 CC(=O)OCC(=O)Nc1ccccc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O18 compound treatment 0.508 0.249 13.38 13.3807 1.0 1402999 TimTec1_002086 Cc1ccc(NC(=O)c2ccc(CSc3ccccn3)cc2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O19 compound treatment 0.285 0.026 1.4 1.3972 1.0 1194370 TimTec1_002087 C=CCON1C(N(CC1=O)C(=O)Nc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O20 compound treatment 0.443 0.184 9.89 9.8878 1.0 3209769 TimTec1_002088 COc1ccc(Sc2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O21 compound treatment 0.28 0.021 1.13 1.1285 1.0 3209770 TimTec1_002089 COc1ccc(CC(C)(N)C(=O)O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O22 compound treatment 0.298 0.039 2.1 2.0958 1.0 3083586 TimTec1_002090 C=CCNC(=S)C(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O23 mock treatment 0.264 0.005 0.27 0.2687 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 O24 mock treatment 0.258 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P01 compound treatment 0.267 0.008 0.43 0.4299 1.0 3083588 TimTec1_002091 Fc1ccc(SCSc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P02 compound treatment 0.332 0.073 3.92 3.9229 1.0 3209771 TimTec1_002092 COc1cc(cc(OC)c1OC)C(=O)Sc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P03 compound treatment 0.529 0.27 14.51 14.5092 1.0 1455929 TimTec1_002093 Clc1ccc(OCC(=O)N2CCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P04 compound treatment 0.277 0.018 0.97 0.9673 1.0 3209887 TimTec1_002094 Cc1ccccc1C(C#N)C(CC#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P05 compound treatment 0.287 0.028 1.5 1.5047 1.0 3209888 TimTec1_002095 NS(=O)(=O)c1ccc(/N=C/c2ccc(C#N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P06 compound treatment 0.25 -0.009 -0.48 -0.4836 -1.0 1275062 TimTec1_002096 OC(=O)C1(CC2CC3C1)CC(C2)(C3)n4cnc(Cl)n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P07 compound treatment 0.279 0.02 1.07 1.0748 1.0 3209889 TimTec1_002097 C/C(=N\n1c(n[nH]c1=O)c2ccccc2)/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P08 compound treatment 0.445 0.186 10.0 9.9953 1.0 3209890 TimTec1_002098 CC(=O)N1c2ccccc2CCc3ccc(NC(=S)NC(=O)/C=C/c4ccccc4)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P09 compound treatment 0.262 0.003 0.16 0.1612 1.0 1360532 TimTec1_002099 O=C(C1CCCNC1=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P10 compound treatment 0.541 0.282 15.15 15.1541 1.0 3083595 TimTec1_002100 Cc1nnc(SCc2c(C)cc(C)cc2C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P11 compound treatment 0.263 0.004 0.21 0.215 1.0 1439208 TimTec1_002101 CC(C)C1C(O)C(=O)C2C3CCCC(C)(C)C3CC(OC(=O)C)C2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P12 compound treatment 0.333 0.074 3.98 3.9766 1.0 1739919 TimTec1_002102 COc1ccc(NC(=O)Nc2ccc(cc2)N3CCCC3=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P13 compound treatment 0.391 0.132 7.09 7.0934 1.0 3209891 TimTec1_002103 C/C(=N/c1ccc(cc1)S(=O)(=O)N2CCOCC2)/Nc3ccc(C(=O)O)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P14 compound treatment 0.425 0.166 8.92 8.9205 1.0 3083596 TimTec1_002104 FC(F)(F)c1cc(NCCC(=O)c2ccccc2)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P15 compound treatment 0.311 0.052 2.79 2.7944 1.0 1614491 TimTec1_002105 Oc1nn(CNc2ccc(F)cc2)c(=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P16 compound treatment 0.31 0.051 2.74 2.7406 1.0 3209892 TimTec1_002106 CC(C)CC1C(=NN(C(=S)c2ccc(C)cc2)C1(C)O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P17 compound treatment 0.353 0.094 5.05 5.0514 1.0 3209893 TimTec1_002107 OC(=O)c1ccccc1C2SCC(=O)N2NC(=S)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P18 compound treatment 0.289 0.03 1.61 1.6121 1.0 1488668 TimTec1_002108 CC(C)(C)NC(=O)c1ccccc1SCc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P19 compound treatment 0.492 0.233 12.52 12.5209 1.0 3209894 TimTec1_002109 CCOC(=O)C1=C(Sc2nnc(n2N=C1N)C(F)(F)F)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P20 compound treatment 0.399 0.14 7.52 7.5233 1.0 1730773 TimTec1_002110 CCC(=O)Nc1sc(Cc2ccccc2)c(C)c1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P21 compound treatment 0.292 0.033 1.77 1.7734 1.0 1494523 TimTec1_002111 COc1cc(cc(OC)c1OC)C(=O)n2c(SCc3ccc(F)cc3)nc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P22 compound treatment 0.367 0.108 5.8 5.8037 1.0 3209895 TimTec1_002112 COC(=O)c1c(NC(=O)Nc2ccccc2)sc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P23 mock treatment 0.249 -0.01 -0.54 -0.5374 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2068 P24 mock treatment 0.256 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A01 compound treatment 0.252 -0.00612 -0.33 -0.3289 -1.0 1161050 TimTec1_002113 COc1cccc(c1)C2C(=C(N)Oc3[nH]c(=O)[nH]c(=O)c23)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A02 compound treatment 0.457 0.199 10.69 10.6873 1.0 3083648 TimTec1_002114 COc1ccccc1NC(=O)c2cccc(c2)N3C(=O)C4CC=CCC4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A03 compound treatment 0.423 0.165 8.86 8.8602 1.0 3209896 TimTec1_002115 COC(=O)c1ccc(NC(=S)N(C(C)C)C(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A04 compound treatment 0.248 -0.0101 -0.54 -0.5439 -1.0 3083650 TimTec1_002116 Fc1ccccc1OC(=O)CCCC(=O)n2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A05 compound treatment 0.296 0.0379 2.04 2.0355 1.0 3209897 TimTec1_002117 C(Nc1ccc(NCc2cccs2)cc1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A06 compound treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 3083652 TimTec1_002118 CCN(CC)C(=S)NC1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A07 compound treatment 0.243 -0.0151 -0.81 -0.8126 -1.0 3209898 TimTec1_002119 Cn1c(=O)c(C/2=NNC(=O)\C2=C/C=C/c3ccccc3)c(O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A08 compound treatment 0.301 0.0429 2.3 2.3042 1.0 1389733 TimTec1_002120 OC1(CCCCC1)c2cc(=N)sc3nc4ccccc4n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A09 compound treatment 0.361 0.103 5.53 5.5285 1.0 3209899 TimTec1_002121 Cn1c(SCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A10 compound treatment 0.27 0.0119 0.64 0.6383 1.0 3209900 TimTec1_002122 CN1C(=O)C(=Cc2ccc(o2)c3cccc(Cl)c3)C(=O)N(C)C1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A11 compound treatment 0.259 8.79E-4 0.05 0.0472 1.0 3083655 TimTec1_002123 CC(Sc1nnnn1c2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A12 compound treatment 0.543 0.285 15.31 15.3088 1.0 1256717 TimTec1_002124 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A13 compound treatment 0.241 -0.0171 -0.92 -0.9201 -1.0 3083658 TimTec1_002125 CCn1c(ccc1c2ccccc2)C(O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A14 compound treatment 0.266 0.00788 0.42 0.4234 1.0 3209901 TimTec1_002126 CN1/C(=C/C(=S)C(C)(C)C)/Sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A15 compound treatment 0.354 0.0959 5.15 5.1523 1.0 1429079 TimTec1_002127 O=C(CC1CCC1)Nc2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A16 compound treatment 0.274 0.0159 0.85 0.8533 1.0 1196328 TimTec1_002128 CC(C)CN(CC(C)C)CN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A17 compound treatment 0.472 0.214 11.49 11.4934 1.0 3083661 TimTec1_002129 Clc1ccc(CSc2n[nH]c(=O)[nH]c2=O)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A18 compound treatment 0.267 0.00888 0.48 0.4771 1.0 1702303 TimTec1_002130 COC(=O)C1CCc2sc(N)c(C(=O)OC)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A19 compound treatment 0.24 -0.0181 -0.97 -0.9738 -1.0 1553773 TimTec1_002131 Oc1ccccc1CNc2ccc(cc2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A20 compound treatment 0.26 0.00188 0.1 0.101 1.0 3083664 TimTec1_002132 CC1CCCCC1NC(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A21 compound treatment 0.292 0.0339 1.82 1.8206 1.0 1072652 TimTec1_002133 O=C(Nc1sc2CCCCc2c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A22 compound treatment 0.289 0.0309 1.66 1.6594 1.0 1225174 TimTec1_002134 Clc1ccccc1NC(=O)N(C(CC(=O)C2CC2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A23 mock treatment 0.265 0.00688 0.37 0.3697 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 A24 mock treatment 0.262 0.00388 0.21 0.2084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B01 compound treatment 0.279 0.0209 1.12 1.122 1.0 3209902 TimTec1_002135 CCC(C)NC(=O)Nc1ccc(Br)cc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B02 mock treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 1402072 TimTec1_002136 CC(NCc1cccs1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B03 compound treatment 0.299 0.0409 2.2 2.1967 1.0 3209903 TimTec1_002137 Cc1ccc(CCNC(=O)NC(C)(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B04 compound treatment 0.287 0.0289 1.55 1.5519 1.0 1539581 TimTec1_002138 O=P(Cc1ccccc1)(N(CC2CCCO2)Cc3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B05 compound treatment 0.445 0.187 10.04 10.0425 1.0 3083710 TimTec1_002139 Clc1ccc(NC(=O)c2ccc(CSc3ncccn3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B06 compound treatment 0.253 -0.00512 -0.28 -0.2752 -1.0 3209904 TimTec1_002140 O=C1OC2(CCCCC2)C(=C1)NCCOC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B07 compound treatment 0.285 0.0269 1.44 1.4444 1.0 3083712 TimTec1_002141 CCOC(=O)c1cc(Br)ccc1OCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B08 compound treatment 0.253 -0.00512 -0.28 -0.2752 -1.0 1534717 TimTec1_002142 Nc1nnnn1CC(=O)OCC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B09 compound treatment 0.271 0.0129 0.69 0.6921 1.0 1230328 TimTec1_002143 NNC(=O)c1nnn(c1CN2CCCCC2)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B10 compound treatment 0.277 0.0189 1.01 1.0145 1.0 3209905 TimTec1_002144 CCN(CC)C(=O)CSc1nc(N)c(C#N)c(CC(C)C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B11 compound treatment 0.451 0.193 10.36 10.3649 1.0 1502579 TimTec1_002145 CCC(=O)Nc1cccc(c1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B12 compound treatment 0.359 0.101 5.42 5.421 1.0 3209906 TimTec1_002146 Cc1ccc2[nH]c(=O)c(/C=N/C(CO)(CO)CO)c(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B13 compound treatment 0.579 0.321 17.24 17.2434 1.0 1455910 TimTec1_002147 O=C(CCc1ccccc1)Nc2ccc(cc2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B14 compound treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 3083716 TimTec1_002148 CC(NC(=S)NC(=O)c1cccs1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B15 compound treatment 0.281 0.0229 1.23 1.2295 1.0 1725795 TimTec1_002149 CC(C)(C)c1ccccc1OCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B16 compound treatment 0.293 0.0349 1.87 1.8743 1.0 3210019 TimTec1_002150 CCC1CC(CNC=C2C(=O)CC(C)(C)CC2=O)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B17 compound treatment 0.272 0.0139 0.75 0.7458 1.0 1148431 TimTec1_002151 CC1CN(CC(C)O1)C(=O)c2cccc(c2)C(=O)N3CC(C)OC(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B18 compound treatment 0.344 0.0859 4.61 4.6149 1.0 3210020 TimTec1_002152 COc1ccc(CCC(=O)Nc2cccc(C)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B19 compound treatment 0.268 0.00988 0.53 0.5309 1.0 1183356 TimTec1_002153 COC(=O)C(c1ccccc1)C2(O)CC(C)N(C)CC2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B20 compound treatment 0.318 0.0599 3.22 3.2178 1.0 3083720 TimTec1_002154 Cc1cc(O)ccc1Sc2ccc(O)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B21 compound treatment 0.265 0.00688 0.37 0.3697 1.0 3210021 TimTec1_002155 CC(C)C1N2C(=S)NC(C)(C)CC2(C)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B22 compound treatment 0.319 0.0609 3.27 3.2715 1.0 1240094 TimTec1_002156 COc1ccccc1C(=O)Nc2ccc(CC#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B23 mock treatment 0.259 8.79E-4 0.05 0.0472 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 B24 mock treatment 0.261 0.00288 0.15 0.1547 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C01 compound treatment 0.281 0.0229 1.23 1.2295 1.0 3210022 TimTec1_002157 OCCNC(=O)c1cccc(c1)C(=O)NCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C02 compound treatment 0.279 0.0209 1.12 1.122 1.0 3210023 TimTec1_002158 Cn1nccc1Nc2ccc(OC(=O)c3ccnn3C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C03 compound treatment 0.356 0.0979 5.26 5.2598 1.0 3083722 TimTec1_002159 COC(=O)c1ccc(NC(=S)N(CC(C)C)CC(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C04 compound treatment 0.231 -0.0271 -1.46 -1.4574 -1.0 3210024 TimTec1_002160 Cc1ccc(OC(=O)c2ccccc2)c(c1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C05 compound treatment 0.267 0.00888 0.48 0.4771 1.0 3083724 TimTec1_002161 OC(=O)CC(Sc1cccs1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C06 compound treatment 0.235 -0.0231 -1.24 -1.2425 -1.0 1038092 TimTec1_002162 Cc1ccc(O)c(c1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C07 compound treatment 0.276 0.0179 0.96 0.9608 1.0 1602769 TimTec1_002163 Cc1ccc(cc1)c2nn(C3OC(CO)C(O)C3O)c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C08 compound treatment 0.473 0.215 11.55 11.5471 1.0 1372480 TimTec1_002164 OC1CC(N(C1)C(=O)Oc2ccccc2)C(=O)OCC(=O)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C09 compound treatment 0.308 0.0499 2.68 2.6804 1.0 3083763 TimTec1_002165 Clc1ccc(cc1Cl)N2NC(=O)/C(=C/C=C/c3ccccc3)/C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C10 compound treatment 0.264 0.00588 0.32 0.3159 1.0 3083765 TimTec1_002166 CC1(C)CC(=O)C/C(=N\c2ccc3[nH]c(=O)[nH]c3c2)/C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C11 compound treatment 0.259 8.79E-4 0.05 0.0472 1.0 3210025 TimTec1_002167 CNC(=O)c1cccc(NC(=S)NC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C12 compound treatment 0.299 0.0409 2.2 2.1967 1.0 3210026 TimTec1_002168 Clc1ccccc1C(=O)Oc2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C13 compound treatment 0.285 0.0269 1.44 1.4444 1.0 1014674 TimTec1_002169 OC(=O)c1ccc([nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C14 compound treatment 0.317 0.0589 3.16 3.164 1.0 1322060 TimTec1_002170 COc1ccccc1C(=O)Nc2ccc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C15 compound treatment 0.529 0.271 14.56 14.5565 1.0 3083771 TimTec1_002171 COC(=O)c1ccccc1/N=C/C=C(/O)\c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C16 compound treatment 0.389 0.131 7.03 7.0332 1.0 1430542 TimTec1_002172 CC(C)c1ccccc1NC(=O)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C17 compound treatment 0.275 0.0169 0.91 0.907 1.0 1190438 TimTec1_002173 OC(=O)c1ccc(CNC(=O)c2cocc2C(=O)O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C18 compound treatment 0.277 0.0189 1.01 1.0145 1.0 1645535 TimTec1_002174 Cc1ccccc1NC(=O)Nc2ccc(OCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C19 compound treatment 0.256 -0.00212 -0.11 -0.114 -1.0 3210027 TimTec1_002175 Clc1ccc(cc1)C2CC(=NN2c3ccccc3)C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C20 compound treatment 0.374 0.116 6.23 6.2271 1.0 1618185 TimTec1_002176 Cc1ccc(cc1)c2ccc(OCC(=O)NC3CCCC3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C21 compound treatment 0.277 0.0189 1.01 1.0145 1.0 1272849 TimTec1_002177 OC(=O)CCc1nc2ccccc2nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C22 compound treatment 0.263 0.00488 0.26 0.2622 1.0 3210028 TimTec1_002178 C(Oc1ccc(/C=N/n2nnnc2Nc3ccccc3)cc1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C23 mock treatment 0.263 0.00488 0.26 0.2622 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 C24 mock treatment 0.259 8.79E-4 0.05 0.0472 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D01 compound treatment 0.398 0.14 7.52 7.5168 1.0 1308579 TimTec1_002179 COc1ccc(CCNC(=O)Nc2ccc(Cl)cc2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D02 compound treatment 0.395 0.137 7.36 7.3556 1.0 3083776 TimTec1_002180 CCSc1nnc(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D03 compound treatment 0.531 0.273 14.66 14.6639 1.0 3210029 TimTec1_002181 Fc1ccccc1NC(=O)CCCCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D04 compound treatment 0.277 0.0189 1.01 1.0145 1.0 1325980 TimTec1_002182 CN1CCN(CC1)C(=S)NC(CC(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D05 compound treatment 0.592 0.334 17.94 17.9419 1.0 3083779 TimTec1_002183 O=C(CSC1=NCCS1)NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D06 compound treatment 0.29 0.0319 1.71 1.7131 1.0 1681619 TimTec1_002184 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccc(cc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D07 compound treatment 0.361 0.103 5.53 5.5285 1.0 3083781 TimTec1_002185 COC(=O)c1ccc(CSc2nccn2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D08 compound treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 1532072 TimTec1_002186 CCN(CC)CCN1C(=O)Cn2c(C)c(C)c3cccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D09 compound treatment 0.532 0.274 14.72 14.7177 1.0 3083783 TimTec1_002187 Clc1ccc(/C=C/C(=O)NCC2CCCO2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D10 compound treatment 0.272 0.0139 0.75 0.7458 1.0 1189768 TimTec1_002188 CCCc1cc(O)nc(SCC(=O)NCC2(CC3CC4CC(C3)C2)C4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D11 compound treatment 0.25 -0.00812 -0.44 -0.4364 -1.0 1607604 TimTec1_002189 CCC(=O)Nc1cc2ccccc2cc1NC(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D12 compound treatment 0.272 0.0139 0.75 0.7458 1.0 1415304 TimTec1_002190 O=C(CC(C1C(=O)NC(=S)NC1=O)c2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D13 compound treatment 0.295 0.0369 1.98 1.9818 1.0 3083786 TimTec1_002191 Cn1c(SCC(=O)NN)nnc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D14 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1536582 TimTec1_002192 CC(=O)OC(OC(=O)C)C1(OC2C=C1)C3C2C(=O)N(C3=O)c4ccc(OC(=O)C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D15 compound treatment 0.462 0.204 10.96 10.956 1.0 3083820 TimTec1_002193 FC(F)(F)Oc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D16 compound treatment 0.245 -0.0131 -0.71 -0.7051 -1.0 3210030 TimTec1_002194 COc1ccc(cc1)C(CC(=O)O)NC(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D17 compound treatment 0.281 0.0229 1.23 1.2295 1.0 1372790 TimTec1_002195 Cc1cccc(N2CCN(CC2)C(=O)CN3C(=O)c4ccccc4C3=O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D18 compound treatment 0.36 0.102 5.47 5.4748 1.0 3210031 TimTec1_002196 COc1ccc(Cl)c(c1)C(=O)OCC(=O)Nc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D19 compound treatment 0.266 0.00788 0.42 0.4234 1.0 1594222 TimTec1_002197 CCC(=O)OC1(Cc2ccc(CC)cc2)CC(C)N(C)CC1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D20 compound treatment 0.264 0.00588 0.32 0.3159 1.0 3083824 TimTec1_002198 S=C(NC1CCCCC1)NN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D21 compound treatment 0.25 -0.00812 -0.44 -0.4364 -1.0 1669241 TimTec1_002199 CC1(O)N(CC(=O)O)C(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D22 compound treatment 0.258 -1.21E-4 -0.01 -0.0065 -1.0 1421950 TimTec1_002200 Nc1ccc(CC(CCC(=O)O)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D23 mock treatment 0.261 0.00288 0.15 0.1547 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 D24 mock treatment 0.255 -0.00312 -0.17 -0.1677 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E01 compound treatment 0.242 -0.0161 -0.87 -0.8663 -1.0 1882539 TimTec1_002201 CCCNC(=O)c1ccccc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E02 compound treatment 0.306 0.0479 2.57 2.5729 1.0 1476398 TimTec1_002202 Fc1ccccc1OC(=O)CCCC(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E03 compound treatment 0.265 0.00688 0.37 0.3697 1.0 3083828 TimTec1_002203 COC(=O)c1ccc(NC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E04 compound treatment 0.239 -0.0191 -1.03 -1.0275 -1.0 3210032 TimTec1_002204 CC(C)(C)c1cc(Cl)cc(c1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E05 compound treatment 0.245 -0.0131 -0.71 -0.7051 -1.0 1345007 TimTec1_002205 COc1ccc(OC)c(c1)S(=O)(=O)c2c(OC)ccc(OC)c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E06 compound treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 1083599 TimTec1_002206 C1CCN(CC1)SN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E07 compound treatment 0.524 0.266 14.29 14.2878 1.0 3083830 TimTec1_002207 Nc1nnc(CSc2cccc3cccnc23)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E08 compound treatment 0.251 -0.00712 -0.38 -0.3827 -1.0 1510605 TimTec1_002208 COC(=O)Nc1c(C)n(C)n(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E09 compound treatment 0.258 -1.21E-4 -0.01 -0.0065 -1.0 3210148 TimTec1_002209 Brc1cccc(c1)N2NC(=O)/C(=C/3\C(=O)Nc4ccccc34)/C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E10 compound treatment 0.314 0.0559 3.0 3.0028 1.0 1411763 TimTec1_002210 CCCc1cc(=O)nc(SCc2nc3ccccc3[nH]2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E11 compound treatment 0.285 0.0269 1.44 1.4444 1.0 3210149 TimTec1_002211 OCCN(CCO)CC(O)C1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E12 compound treatment 0.256 -0.00212 -0.11 -0.114 -1.0 1920607 TimTec1_002212 CC(C)CN(CC(C)C)C(=O)Nc1ccccc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E13 compound treatment 0.36 0.102 5.47 5.4748 1.0 1527966 TimTec1_002213 Cc1cc(C)cc(OCc2ccc(o2)C(=O)NN)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E14 compound treatment 0.27 0.0119 0.64 0.6383 1.0 1183896 TimTec1_002214 CN(Cc1c(C)nc2c(C)cc(C)cc2c1O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E15 compound treatment 0.256 -0.00212 -0.11 -0.114 -1.0 3083835 TimTec1_002215 CC1(C)CC(CC(C)(C)N1)/N=C/c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E16 compound treatment 0.488 0.23 12.35 12.3532 1.0 1259208 TimTec1_002216 CC(C)CN(CC(C)C)C(=O)COc1ccc(cc1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E17 compound treatment 0.29 0.0319 1.71 1.7131 1.0 1657881 TimTec1_002217 COc1cc2CCN3CC(CC(C)C)C(=O)CC3c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E18 compound treatment 0.509 0.251 13.48 13.4817 1.0 1561850 TimTec1_002218 O=C(Nc1ccc(cc1)C(=O)OC2CCCCC2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E19 compound treatment 0.613 0.355 19.07 19.0704 1.0 3210150 TimTec1_002219 COc1ccc(/C=C\2/SC(=S)N(CCC(=O)O)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E20 compound treatment 0.389 0.131 7.03 7.0332 1.0 1395502 TimTec1_002220 O=C(CCc1ccccc1)Nc2ccc(cc2)C(=O)OC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E21 compound treatment 0.302 0.0439 2.36 2.358 1.0 3210151 TimTec1_002221 OC(=O)CCCNc1ncnc2ccc(Br)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E22 compound treatment 0.525 0.267 14.34 14.3415 1.0 1511409 TimTec1_002222 O=C1NC(=O)C(CCc2ccncc2)(CCc3ccncc3)C(=O)N1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E23 mock treatment 0.251 -0.00712 -0.38 -0.3827 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 E24 mock treatment 0.279 0.0209 1.12 1.122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F01 compound treatment 0.286 0.0279 1.5 1.4981 1.0 3083870 TimTec1_002223 Cc1ccc(NC(=O)Nc2ccc(cc2)C(C)(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F02 compound treatment 0.368 0.11 5.9 5.9047 1.0 3210152 TimTec1_002224 NC(=O)c1sc2NC3=C(C(c2c1N)c4ccc(Cl)cc4)C(=O)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F03 compound treatment 0.505 0.247 13.27 13.2667 1.0 3083874 TimTec1_002225 NC1=C(C#N)C(C(=C(N)O1)C#N)c2cc(Br)cs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F04 compound treatment 0.285 0.0269 1.44 1.4444 1.0 1118827 TimTec1_002226 CC(NC(=O)c1ccccc1OCC(=O)NC2(CC3CC4CC(C3)C2)C4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F05 compound treatment 0.429 0.171 9.18 9.1827 1.0 3083876 TimTec1_002227 O=C(COc1ccccc1)N2CCNC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F06 compound treatment 0.473 0.215 11.55 11.5471 1.0 1468407 TimTec1_002228 NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(c3ccco3)n2CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F07 compound treatment 0.439 0.181 9.72 9.72 1.0 3083878 TimTec1_002229 COC(=O)c1ccc(COc2ccccc2Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F08 compound treatment 0.26 0.00188 0.1 0.101 1.0 3210153 TimTec1_002230 Nc1cc(=O)[nH]c(=O)n1CC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F09 compound treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 3083880 TimTec1_002231 O=C(NC1CCCCCC1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F10 compound treatment 0.525 0.267 14.34 14.3415 1.0 1289043 TimTec1_002232 O=C(CSc1nc2ccccc2s1)NCCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F11 compound treatment 0.3 0.0419 2.25 2.2505 1.0 1333172 TimTec1_002233 Brc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F12 compound treatment 0.252 -0.00612 -0.33 -0.3289 -1.0 1335464 TimTec1_002234 CCn1ccnc1P(=O)(N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F13 compound treatment 0.295 0.0369 1.98 1.9818 1.0 3083883 TimTec1_002235 CCN(CC)/C=C/1\SC(=S)N(C1=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F14 compound treatment 0.529 0.271 14.56 14.5565 1.0 3210154 TimTec1_002236 COc1cc(/C=c/2\sc3=NN=C(C(c4ccccc4)n3\c2=N\CCO)c5ccccc5)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F15 compound treatment 0.6 0.342 18.37 18.3719 1.0 3083885 TimTec1_002237 COc1ccc(NC(=O)CCCOc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F16 compound treatment 0.248 -0.0101 -0.54 -0.5439 -1.0 3210155 TimTec1_002238 O=C(C(c1ccccc1)c2ccccc2)N3CCNC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F17 compound treatment 0.523 0.265 14.23 14.234 1.0 3210156 TimTec1_002239 Oc1ccc2ccccc2c1/C=N/c3ccc(cc3)S(=O)(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F18 compound treatment 0.276 0.0179 0.96 0.9608 1.0 3083888 TimTec1_002240 CC(C)(C)c1ccc(cc1)C(=O)n2cc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F19 compound treatment 0.24 -0.0181 -0.97 -0.9738 -1.0 3210157 TimTec1_002241 Cc1sc(C)c(CNc2ccccc2)c1CNc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F20 compound treatment 0.308 0.0499 2.68 2.6804 1.0 3083890 TimTec1_002242 C/C=C/C(=O)c1cc(Cl)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F21 compound treatment 0.3 0.0419 2.25 2.2505 1.0 3083891 TimTec1_002243 CC(C)c1c(C#N)c(N)nc(SCC(=O)N)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F22 compound treatment 0.299 0.0409 2.2 2.1967 1.0 3210158 TimTec1_002244 CC(C)c1nc2c(Br)cc(Br)cc2c(=S)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F23 mock treatment 0.25 -0.00812 -0.44 -0.4364 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 F24 mock treatment 0.258 -1.21E-4 -0.01 -0.0065 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G01 compound treatment 0.259 8.79E-4 0.05 0.0472 1.0 3210159 TimTec1_002245 O=C(Nc1ccccc1)Nc2ccccc2C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G02 compound treatment 0.256 -0.00212 -0.11 -0.114 -1.0 3083894 TimTec1_002246 CC1CCC(CC1)OC(=O)CCC(=O)Nc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G03 compound treatment 0.335 0.0769 4.13 4.1313 1.0 1604712 TimTec1_002247 CNC(=O)Nc1ccc(cc1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G04 compound treatment 0.32 0.0619 3.33 3.3252 1.0 3083896 TimTec1_002248 CC(C)Nc1ccc(cc1)n2nc3ccccc3[n+]2[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G05 compound treatment 0.583 0.325 17.46 17.4583 1.0 3210160 TimTec1_002249 COc1ccc2nc(sc2c1)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G06 compound treatment 0.276 0.0179 0.96 0.9608 1.0 3083961 TimTec1_002250 CC(C)(C)c1ccc(O)c(c1)C(=O)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G07 compound treatment 0.269 0.0109 0.58 0.5846 1.0 1508878 TimTec1_002251 Cc1ccc(cc1C)C(=O)COC(=O)C2C(C3CC2C=C3)C(=O)OCC(=O)c4ccc(C)c(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G08 compound treatment 0.338 0.0799 4.29 4.2925 1.0 1208353 TimTec1_002252 N#Cc1nc(oc1NCCN2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G09 compound treatment 0.597 0.339 18.21 18.2106 1.0 3210161 TimTec1_002253 CCOc1ccc(/C=C/2\NC(=S)NC2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G10 compound treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 3083965 TimTec1_002254 O=c/1[nH]\c(=C\c2ccco2)\c(=O)[nH]\c1=C/c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G11 compound treatment 0.277 0.0189 1.01 1.0145 1.0 3210162 TimTec1_002255 CCOC(=O)C1=C(C)OC2=C(C1c3ccc(CC)s3)C(=O)CC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G12 compound treatment 0.285 0.0269 1.44 1.4444 1.0 1549435 TimTec1_002256 OC(=O)CNc1nc(nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G13 compound treatment 0.271 0.0129 0.69 0.6921 1.0 3210163 TimTec1_002257 Cc1cc(nc2cc(nn12)C(=O)Nc3ccccc3C(F)(F)F)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G14 compound treatment 0.304 0.0459 2.47 2.4654 1.0 3083968 TimTec1_002258 Brc1ccc2ncn(CC=C)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G15 compound treatment 0.567 0.309 16.6 16.5985 1.0 3210164 TimTec1_002259 O/C(=C/C=N/Cc1ccccc1)/c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G16 compound treatment 0.429 0.171 9.18 9.1827 1.0 3083970 TimTec1_002260 CCc1ccc(OCCCC(=O)Nc2nnc[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G17 compound treatment 0.284 0.0259 1.39 1.3907 1.0 1157670 TimTec1_002261 Fc1ccc(cc1)C(=O)CNc2ccc3c(c2)oc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G18 compound treatment 0.273 0.0149 0.8 0.7996 1.0 1710239 TimTec1_002262 CC(C)c1cccc(C)c1NC(=O)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G19 compound treatment 0.32 0.0619 3.33 3.3252 1.0 3210165 TimTec1_002263 S=C(N/C(=N/c1ccccc1)/c2ccccc2)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G20 compound treatment 0.285 0.0269 1.44 1.4444 1.0 1693000 TimTec1_002264 CCS(=O)(=O)c1ccc(NC(=O)c2ccccc2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G21 compound treatment 0.308 0.0499 2.68 2.6804 1.0 1686276 TimTec1_002265 CCOC(=O)c1cnc2c(C)cc(Cl)cc2c1NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G22 compound treatment 0.556 0.298 16.01 16.0074 1.0 1208703 TimTec1_002266 CCc1ccc(cc1)C2=CC(C(C#N)C(=O)N2)c3cccc(Br)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G23 mock treatment 0.259 8.79E-4 0.05 0.0472 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 G24 mock treatment 0.253 -0.00512 -0.28 -0.2752 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H01 compound treatment 0.419 0.161 8.65 8.6453 1.0 3083974 TimTec1_002267 COc1cccc(NC(=O)Nc2nncs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H02 compound treatment 0.351 0.0929 4.99 4.9911 1.0 3210281 TimTec1_002268 Cc1ccc(NC(=O)COC(=O)CSc2nnc([nH]2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H03 compound treatment 0.331 0.0729 3.92 3.9164 1.0 3083976 TimTec1_002269 O=c1oc(ns1)c2cc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H04 compound treatment 0.276 0.0179 0.96 0.9608 1.0 3210282 TimTec1_002270 Cc1ccc2c(nc3s/c(=C\c4ccc(o4)c5ccccc5F)/c(=O)n32)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H05 compound treatment 0.347 0.0889 4.78 4.7762 1.0 3083979 TimTec1_002271 O=C(CSc1ccccn1)NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H06 compound treatment 0.288 0.0299 1.61 1.6056 1.0 1698408 TimTec1_002272 NC(=O)C1C(=NC(=C(C#N)C21CCCCC2)N)SCC(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H07 compound treatment 0.414 0.156 8.38 8.3766 1.0 3083981 TimTec1_002273 COc1ccccc1/C=C/C(=O)Nc2sc3CCCc3c2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H08 compound treatment 0.268 0.00988 0.53 0.5309 1.0 1633716 TimTec1_002274 CC1CCN(CC1)C(=O)c2scc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H09 compound treatment 0.339 0.0809 4.35 4.3463 1.0 1434772 TimTec1_002275 Cc1cccc(NC(=O)c2cccc(Br)c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H10 compound treatment 0.587 0.329 17.67 17.6733 1.0 1459322 TimTec1_002276 COC(=O)c1ccc2CN(Cc2c1)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H11 compound treatment 0.271 0.0129 0.69 0.6921 1.0 1227803 TimTec1_002277 CC(=O)Oc1ccc(cc1)C(C)(C)c2ccc(OC(=O)C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H12 compound treatment 0.319 0.0609 3.27 3.2715 1.0 1246806 TimTec1_002278 O=C(COc1ccccc1)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H13 compound treatment 0.26 0.00188 0.1 0.101 1.0 3210283 TimTec1_002279 C[C@@H](N1C[C@@H](CO)OC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H14 compound treatment 0.311 0.0529 2.84 2.8416 1.0 1334040 TimTec1_002280 OC(=O)CCN1CCn2c3C1CCCc3c4cc(ccc24)C5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H15 compound treatment 0.26 0.00188 0.1 0.101 1.0 3084053 TimTec1_002281 CCCNC(=O)N(C)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H16 compound treatment 0.306 0.0479 2.57 2.5729 1.0 1566880 TimTec1_002282 CCOc1ccc(NC(=O)Cc2ccccc2OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H17 compound treatment 0.269 0.0109 0.58 0.5846 1.0 1399838 TimTec1_002283 CC(C)N1C(n2oc(=O)n(c3cccc(Cl)c3)c2=O)C(C)(C)SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H18 compound treatment 0.262 0.00388 0.21 0.2084 1.0 3084055 TimTec1_002284 Cc1ccccc1C(=O)n2cc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H19 compound treatment 0.588 0.33 17.73 17.727 1.0 3210284 TimTec1_002285 CCSc1nnc2n(/N=C/c3cccs3)cnn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H20 compound treatment 0.287 0.0289 1.55 1.5519 1.0 3210285 TimTec1_002286 O=C(CSc1nnc(c2ccccc2)n1c3ccccc3)NC4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H21 compound treatment 0.378 0.12 6.44 6.442 1.0 1379455 TimTec1_002287 NS(=O)(=O)c1ccc(NC(=O)COC(=O)c2cccc(c2)N3C(=O)CCC3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H22 compound treatment 0.27 0.0119 0.64 0.6383 1.0 3210286 TimTec1_002288 CC(Sc1ccc(Cl)cc1)C(=O)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H23 mock treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 H24 mock treatment 0.266 0.00788 0.42 0.4234 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I01 compound treatment 0.277 0.0189 1.01 1.0145 1.0 3084057 TimTec1_002289 COC(=O)c1ccc(NC(=S)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I02 compound treatment 0.25 -0.00812 -0.44 -0.4364 -1.0 3210287 TimTec1_002290 CCOc1ccc(NC(=O)C2CC=CCC2C(=O)OC(C)CC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I03 compound treatment 0.252 -0.00612 -0.33 -0.3289 -1.0 1638709 TimTec1_002291 CNC(=O)Nc1ccc(cc1)C(=O)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I04 compound treatment 0.351 0.0929 4.99 4.9911 1.0 1005018 TimTec1_002292 Oc1ccc(Cl)cc1Sc2cc(Cl)ccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I05 compound treatment 0.315 0.0569 3.06 3.0565 1.0 3210288 TimTec1_002293 Cc1cccc2c(O)c(/C=C/3\C(NN(C3=O)c4ccccc4)c5ccccc5)c(=O)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I06 compound treatment 0.265 0.00688 0.37 0.3697 1.0 1025812 TimTec1_002294 CNC(=O)c1ccc(N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I07 compound treatment 0.387 0.129 6.93 6.9257 1.0 3210289 TimTec1_002295 O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I08 compound treatment 0.27 0.0119 0.64 0.6383 1.0 1738195 TimTec1_002296 Cc1ccc(cc1)N(C(=O)COc2c(C)cccc2C)S(=O)(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I09 compound treatment 0.656 0.398 21.38 21.3812 1.0 3210290 TimTec1_002297 O=C/1NC(=S)S\C1=C\c2ccc(o2)c3ccc4C(=O)NC(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I10 compound treatment 0.273 0.0149 0.8 0.7996 1.0 3084063 TimTec1_002298 Nc1cc(O)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I11 compound treatment 0.308 0.0499 2.68 2.6804 1.0 3210291 TimTec1_002299 CC(=C)C(=O)OCCc1ccc(O)c(c1)n2nc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I12 compound treatment 0.264 0.00588 0.32 0.3159 1.0 1195244 TimTec1_002300 Cc1cc(Nc2ccc(Cl)cc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I13 compound treatment 0.272 0.0139 0.75 0.7458 1.0 3210292 TimTec1_002301 FC(F)(F)c1ccccc1CN2CCN(CC3CC4CC3C=C4)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I14 compound treatment 0.33 0.0719 3.86 3.8626 1.0 1020410 TimTec1_002302 Nc1ccc(cc1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I15 compound treatment 0.302 0.0439 2.36 2.358 1.0 1667680 TimTec1_002303 CC(Sc1nc(C)c(Oc2ccccc2)c(O)n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I16 compound treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 3084067 TimTec1_002304 Cc1ccc(OCc2ccc(Cl)cc2)c(c1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I17 compound treatment 0.284 0.0259 1.39 1.3907 1.0 1430919 TimTec1_002305 Cc1nonc1N(Cc2ccc(F)cc2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I18 compound treatment 0.613 0.355 19.07 19.0704 1.0 3210293 TimTec1_002306 O=C(CCCOc1ccccc1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I19 compound treatment 0.399 0.141 7.57 7.5705 1.0 1603996 TimTec1_002307 N#Cc1nc(oc1N2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I20 compound treatment 0.268 0.00988 0.53 0.5309 1.0 1030356 TimTec1_002308 O=C(Nc1ccccc1)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I21 compound treatment 0.277 0.0189 1.01 1.0145 1.0 3210294 TimTec1_002309 CCOC(=O)c1cnc2ccc(OCC)cc2c1NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I22 compound treatment 0.278 0.0199 1.07 1.0682 1.0 3084138 TimTec1_002310 Cc1cccc(CC2(Cc3cccc(C)c3)C(=O)OC(C)(C)OC2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I23 mock treatment 0.283 0.0249 1.34 1.3369 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 I24 mock treatment 0.27 0.0119 0.64 0.6383 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J01 compound treatment 0.429 0.171 9.18 9.1827 1.0 3210295 TimTec1_002311 Clc1cccc(NC(=O)Nc2nncs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J02 compound treatment 0.268 0.00988 0.53 0.5309 1.0 3210296 TimTec1_002312 CCN1/C(=c\2/sc3nc4ccccc4n3c2=O)/Sc5ccc(OC)cc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J03 compound treatment 0.281 0.0229 1.23 1.2295 1.0 3084141 TimTec1_002313 O=c1oc(ns1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J04 compound treatment 0.263 0.00488 0.26 0.2622 1.0 1542017 TimTec1_002314 CCOC(=O)C1C(C(C(=O)OCC)C(=O)CC1=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J05 compound treatment 0.344 0.0859 4.61 4.6149 1.0 3084143 TimTec1_002315 N=C1SCC(=O)N1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J06 compound treatment 0.259 8.79E-4 0.05 0.0472 1.0 1449538 TimTec1_002316 O=C(NCc1cccnc1)NC2(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J07 compound treatment 0.402 0.144 7.73 7.7317 1.0 3084144 TimTec1_002317 N/C(=N\O)/c1ccc(NC(=O)c2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J08 compound treatment 0.385 0.127 6.82 6.8182 1.0 1594153 TimTec1_002318 CN(C)c1nc(F)c(F)c(c1F)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J09 compound treatment 0.268 0.00988 0.53 0.5309 1.0 1187969 TimTec1_002319 Cn1cc(Cl)c(n1)C(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J10 compound treatment 0.273 0.0149 0.8 0.7996 1.0 1126252 TimTec1_002320 CC(C)OC1(O)C(=O)c2ccccc2C(=O)C1(O)OC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J11 compound treatment 0.329 0.0709 3.81 3.8089 1.0 1344052 TimTec1_002321 Cc1ccc(cc1)S(=O)(=O)Nc2c[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J12 compound treatment 0.288 0.0299 1.61 1.6056 1.0 1290298 TimTec1_002322 O=C(Nc1nccs1)c2ccccc2C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J13 compound treatment 0.261 0.00288 0.15 0.1547 1.0 1039552 TimTec1_002323 CCC(N)Cc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J14 compound treatment 0.248 -0.0101 -0.54 -0.5439 -1.0 1270186 TimTec1_002324 O=C(Oc1nsnc1N2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J15 compound treatment 0.492 0.234 12.57 12.5682 1.0 1075811 TimTec1_002325 CCN(C(=O)c1ccc(cc1)C(=O)N(CC)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J16 compound treatment 0.468 0.21 11.28 11.2784 1.0 3084150 TimTec1_002326 CCOc1ccc(NC(=O)CCc2ccc(OC)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J17 compound treatment 0.267 0.00888 0.48 0.4771 1.0 3210404 TimTec1_002327 CC(C)(C)C(=O)CSc1nc(N)c(C#N)c(c2cccs2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J18 compound treatment 0.266 0.00788 0.42 0.4234 1.0 1921516 TimTec1_002328 Cc1cc(C)n(n1)C(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J19 compound treatment 0.286 0.0279 1.5 1.4981 1.0 1585601 TimTec1_002329 COc1ccc(NC(=O)C2(C)c3ccccc3-c4ccccc42)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J20 compound treatment 0.618 0.36 19.34 19.3391 1.0 1485338 TimTec1_002330 Cc1ccn2cc(nc2c1)c3ccc(O)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J21 compound treatment 0.238 -0.0201 -1.08 -1.0813 -1.0 3210405 TimTec1_002331 S=P(c1ccccc1)(c2ccccc2)C3(CCCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J22 compound treatment 0.595 0.337 18.1 18.1032 1.0 3084154 TimTec1_002332 CN(C)/C=N/c1nnc(s1)N2CCN(CC2)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J23 mock treatment 0.255 -0.00312 -0.17 -0.1677 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 J24 mock treatment 0.256 -0.00212 -0.11 -0.114 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K01 compound treatment 0.249 -0.00912 -0.49 -0.4902 -1.0 3210406 TimTec1_002333 COC(=O)c1ccccc1NC(=S)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K02 compound treatment 0.395 0.137 7.36 7.3556 1.0 3210407 TimTec1_002334 CCC(C)OC(=O)C1CC=CCC1C(=O)Nc2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K03 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 3084226 TimTec1_002335 CC(C)(C)Sc1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K04 compound treatment 0.251 -0.00712 -0.38 -0.3827 -1.0 3084228 TimTec1_002336 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)C(C)(C)NO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K05 compound treatment 0.515 0.257 13.8 13.8041 1.0 3210408 TimTec1_002337 C/C(=C/C(=O)c1c(O)c2ccccc2n(C)c1=O)/Nc3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K06 compound treatment 0.557 0.299 16.06 16.0611 1.0 1115526 TimTec1_002338 COC(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K07 compound treatment 0.279 0.0209 1.12 1.122 1.0 1577631 TimTec1_002339 COc1cc(cc(OC)c1OC)C(=O)C(C#N)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K08 compound treatment 0.489 0.231 12.41 12.4069 1.0 1662490 TimTec1_002340 COc1ccc(cc1)N(C(=O)c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K09 compound treatment 0.365 0.107 5.74 5.7434 1.0 3210409 TimTec1_002341 CC/1=NN(C(=O)\C1=C/c2ccc(o2)c3ccc(cc3)S(=O)(=O)N)c4ccc(C)c(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K10 compound treatment 0.439 0.181 9.72 9.72 1.0 3084233 TimTec1_002342 Cc1ccc2nc(sc2c1)c3ccc(/N=C/c4c[nH]c5ccccc45)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K11 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1879124 TimTec1_002343 C(/C=C/c1ccccc1)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K12 compound treatment 0.255 -0.00312 -0.17 -0.1677 -1.0 1460330 TimTec1_002344 Cc1cc(NCc2ccco2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K13 compound treatment 0.336 0.0779 4.19 4.185 1.0 3210411 TimTec1_002345 COc1ccc(NC(=O)C2CCCCN2/N=C/c3ccc(OC)c(OCC(C)C)c3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K14 compound treatment 0.489 0.231 12.41 12.4069 1.0 1358271 TimTec1_002346 O=C(N1CCCc2ccccc12)c3cc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K15 compound treatment 0.289 0.0309 1.66 1.6594 1.0 1526938 TimTec1_002347 CC1(C2C(C=CC1c3ccccc3)c4ccccc4)C(=O)N(CCC5=CCCCC5)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K16 compound treatment 0.248 -0.0101 -0.54 -0.5439 -1.0 1395232 TimTec1_002348 CC(C)(C)c1ccc(OCC(=O)NC(c2ccccc2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K17 compound treatment 0.36 0.102 5.47 5.4748 1.0 3210412 TimTec1_002349 O=C(Cc1ccccc1)Oc2ccc(/N=C/c3cccs3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K18 compound treatment 0.28 0.0219 1.18 1.1757 1.0 3084236 TimTec1_002350 CC(C)c1cccc(C(C)C)c1NC(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K19 compound treatment 0.352 0.0939 5.04 5.0448 1.0 3210413 TimTec1_002351 OC(CN1C(=O)S/C(=C/c2ccccc2)/C1=O)Cn3c4ccccc4c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K20 compound treatment 0.435 0.177 9.51 9.5051 1.0 3084237 TimTec1_002352 Cc1ccccc1OCCCC(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K21 compound treatment 0.49 0.232 12.46 12.4607 1.0 3210414 TimTec1_002353 CC(Sc1ncnc2sc3CCCCc3c12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K22 compound treatment 0.3 0.0419 2.25 2.2505 1.0 1464155 TimTec1_002354 CC1=CC(C)(C)N(C(=O)c2ccccc2)c3ccc(OC(=O)c4ccccc4)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K23 mock treatment 0.256 -0.00212 -0.11 -0.114 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 K24 mock treatment 0.262 0.00388 0.21 0.2084 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L01 compound treatment 0.256 -0.00212 -0.11 -0.114 -1.0 3210415 TimTec1_002355 Cc1cc(NC(=O)NC(C)(C)C)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L02 compound treatment 0.468 0.21 11.28 11.2784 1.0 3084239 TimTec1_002356 CC1CCN(CC1)C(=O)/C=C\c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L03 compound treatment 0.292 0.0339 1.82 1.8206 1.0 3210416 TimTec1_002357 CC(=O)Nc1sc2CCCCc2c1c3nsc(=O)o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L04 compound treatment 0.271 0.0129 0.69 0.6921 1.0 1127427 TimTec1_002358 CC(C)(C)NC(=O)Cn1c(nc2ccccc12)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L05 compound treatment 0.287 0.0289 1.55 1.5519 1.0 3084242 TimTec1_002359 O=c1[nH]cc(Sc2cccc3cccnc23)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L06 compound treatment 0.255 -0.00312 -0.17 -0.1677 -1.0 1461401 TimTec1_002360 CC1(O)N(Cc2ccccn2)C(=O)OC31CC(C)(C)NC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L07 compound treatment 0.262 0.00388 0.21 0.2084 1.0 3084243 TimTec1_002361 OC(=O)C1CSC(N1)C2CCC=CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L08 compound treatment 0.299 0.0409 2.2 2.1967 1.0 1709669 TimTec1_002362 O=C(CSc1nc2ccccc2o1)NCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L09 compound treatment 0.262 0.00388 0.21 0.2084 1.0 3084245 TimTec1_002363 Brc1cnn(c1)C(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L10 compound treatment 0.276 0.0179 0.96 0.9608 1.0 3210417 TimTec1_002364 Cc1ccc(/C=N/N2C(=O)C3C4C=CC(C3C2=O)C54CC5)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L11 compound treatment 0.55 0.292 15.68 15.685 1.0 1712043 TimTec1_002365 O=C(Nc1cccc(c1)c2nc3ccccc3[nH]2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L12 compound treatment 0.293 0.0349 1.87 1.8743 1.0 1574585 TimTec1_002366 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)c3cc4ccccc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L13 compound treatment 0.26 0.00188 0.1 0.101 1.0 3423047 TimTec1_002367 NNC(=O)CCCCC1SCC2NC(=O)NC12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L14 compound treatment 0.338 0.0799 4.29 4.2925 1.0 1216605 TimTec1_002368 Oc1ccc2ccccc2c1CN3CCN(Cc4ccc5OCOc5c4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L15 compound treatment 0.299 0.0409 2.2 2.1967 1.0 1280719 TimTec1_002369 CCN(Cc1ccccc1)C(=O)c2ccc(cc2)C(=O)N(CC)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L16 compound treatment 0.378 0.12 6.44 6.442 1.0 3084319 TimTec1_002370 COC(=O)c1ccccc1NC(=O)CCc2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L17 compound treatment 0.436 0.178 9.56 9.5588 1.0 1598426 TimTec1_002371 CC(C)(C)Nc1nc(Cl)nc(n1)N(CN2C(=O)c3ccccc3S2(=O)=O)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L18 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 3084321 TimTec1_002372 Fc1ccc(cc1)C(=O)n2cc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L19 compound treatment 0.267 0.00888 0.48 0.4771 1.0 3210418 TimTec1_002373 COc1ccc(OC)c(/C=N/N2C(=O)C3C4C=CC(C3C2=O)C54CC5)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L20 compound treatment 0.313 0.0549 2.95 2.9491 1.0 1442776 TimTec1_002374 O=S(=O)(Nc1ccc2OC3(CCCCC3)Oc2c1)c4ccc5ccccc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L21 compound treatment 0.281 0.0229 1.23 1.2295 1.0 1471128 TimTec1_002375 CS(=O)(=O)C1=C(N)C(=O)N(C1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L22 compound treatment 0.296 0.0379 2.04 2.0355 1.0 3210419 TimTec1_002376 CC/N=C/1\S/C(=C\c2cn(nc2c3ccccc3)C(=O)C)/C(=O)N1CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L23 mock treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 L24 mock treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M01 compound treatment 0.378 0.12 6.44 6.442 1.0 3084325 TimTec1_002377 COC(=O)c1ccccc1NC(=S)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M02 compound treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 3210420 TimTec1_002378 CC(=O)Nc1ccc(NC(=O)C2CC=CCC2C(=O)OCC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M03 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1268388 TimTec1_002379 CC(C)(C)S(=O)(=O)c1ccc(cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M04 compound treatment 0.21 -0.0481 -2.59 -2.5859 -1.0 1008465 TimTec1_002380 CC(C)(c1ccccc1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M05 compound treatment 0.316 0.0579 3.11 3.1103 1.0 3210421 TimTec1_002381 Cn1c(=O)c(C(=O)/C=C/C=C/c2ccccc2)c(O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M06 compound treatment 0.279 0.0209 1.12 1.122 1.0 1115325 TimTec1_002382 CC(=O)Nc1ccc(cc1)C(=O)NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M07 compound treatment 0.539 0.281 15.09 15.0938 1.0 3084329 TimTec1_002383 COc1cccc(OCCSc2nc3ccccc3s2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M08 compound treatment 0.279 0.0209 1.12 1.122 1.0 1718621 TimTec1_002384 COc1ccc(cc1)N(C(=O)C)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M09 compound treatment 0.251 -0.00712 -0.38 -0.3827 -1.0 3210534 TimTec1_002385 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(OCC)c(OCC)c3)/C2=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M10 compound treatment 0.379 0.121 6.5 6.4958 1.0 3084332 TimTec1_002386 NC(=O)c1ccccc1/N=C/c2ccc(Br)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M11 compound treatment 0.363 0.105 5.64 5.636 1.0 3084333 TimTec1_002387 CC(C)c1cc[nH]c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M12 compound treatment 0.281 0.0229 1.23 1.2295 1.0 1512531 TimTec1_002388 Cc1cccc(Oc2cc(C)nc3ccc(C)cc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M13 compound treatment 0.319 0.0609 3.27 3.2715 1.0 3084336 TimTec1_002389 CCOC(=O)C(C)Sc1nc(N)nc(SC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M14 compound treatment 0.27 0.0119 0.64 0.6383 1.0 3210535 TimTec1_002390 CS(=O)(=O)Nc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M15 compound treatment 0.268 0.00988 0.53 0.5309 1.0 1144104 TimTec1_002391 CC1OS(=O)OC1(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M16 compound treatment 0.493 0.235 12.62 12.6219 1.0 1527653 TimTec1_002392 CCCOC(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M17 compound treatment 0.309 0.0509 2.73 2.7341 1.0 3083234 TimTec1_002393 Cc1ccc(cc1)C(=O)Oc2ccc(/C=N/c3cccs3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M18 compound treatment 0.245 -0.0131 -0.71 -0.7051 -1.0 1460929 TimTec1_002394 Cn1nccc1C(=O)NCCN2C(=O)OC3(CCCCC3)C2(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M19 compound treatment 0.34 0.0819 4.4 4.4 1.0 3083237 TimTec1_002395 Nc1c(n[nH]c1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M20 compound treatment 0.493 0.235 12.62 12.6219 1.0 3210536 TimTec1_002396 CCc1ccc(OCCCC(=O)NCc2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M21 compound treatment 0.3 0.0419 2.25 2.2505 1.0 3083239 TimTec1_002397 Oc1ccc(Br)cc1/C=N\S(=O)(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M22 compound treatment 0.302 0.0439 2.36 2.358 1.0 1432671 TimTec1_002398 O=C(C(Sc1ccccc1)c2ccccc2)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M23 mock treatment 0.264 0.00588 0.32 0.3159 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 M24 mock treatment 0.269 0.0109 0.58 0.5846 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N01 compound treatment 0.273 0.0149 0.8 0.7996 1.0 3083240 TimTec1_002399 Cc1csc(NC(=O)NC(C)(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N02 compound treatment 0.267 0.00888 0.48 0.4771 1.0 3210537 TimTec1_002400 FC(F)(F)c1ccc(cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N03 compound treatment 0.472 0.214 11.49 11.4934 1.0 3210538 TimTec1_002401 CSc1nsc(SCc2ccc(cc2)C(=O)Nc3ccc(Cl)cc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N04 compound treatment 0.269 0.0109 0.58 0.5846 1.0 1438663 TimTec1_002402 COC(=O)c1sc(C(=O)OC)c2OCCOc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N05 compound treatment 0.321 0.0629 3.38 3.379 1.0 1361986 TimTec1_002403 O=C(Nc1nc2ccccc2s1)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N06 compound treatment 0.259 8.79E-4 0.05 0.0472 1.0 1212434 TimTec1_002404 O=C(NC1(CC2CC3CC(C2)C1)C3)C4CCCN4S(=O)(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N07 compound treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 3083244 TimTec1_002405 CC(C1NC(CS1)C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N08 compound treatment 0.257 -0.00112 -0.06 -0.0603 -1.0 1224464 TimTec1_002406 COc1ccccc1CN(C2CC(C)(C)N(C(=O)C)C(C)(C)C2)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N09 compound treatment 0.489 0.231 12.41 12.4069 1.0 1304876 TimTec1_002407 Oc1ccccc1NC(=O)c2cc(NC(=O)c3ccccc3)cc(c2)C(=O)Nc4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N10 compound treatment 0.335 0.0769 4.13 4.1313 1.0 1473339 TimTec1_002408 Brc1cccc(Cn2ccc(NC3CCCC3)nc2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N11 compound treatment 0.411 0.153 8.22 8.2154 1.0 1341588 TimTec1_002409 O=C(COc1ccccc1)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N12 compound treatment 0.373 0.115 6.17 6.1733 1.0 1327761 TimTec1_002410 Cc1ccc2nc(NC(=O)C3CC(O)CN3C(=O)Oc4ccccc4)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N13 compound treatment 0.3 0.0419 2.25 2.2505 1.0 3210539 TimTec1_002411 CCN(CC)c1ccc(/N=C/c2cc(C)n(c2C)c3ccc(OC(=O)C)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N14 compound treatment 0.548 0.29 15.58 15.5775 1.0 1381502 TimTec1_002412 Cn1c(CSc2nc3ccccc3s2)nnc1SCC(=O)NCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N15 compound treatment 0.304 0.0459 2.47 2.4654 1.0 1470780 TimTec1_002413 O=C(N1CCc2ccccc2C1)c3ccc(cc3)C(=O)N4CCc5ccccc5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N16 compound treatment 0.282 0.0239 1.28 1.2832 1.0 3083248 TimTec1_002414 COC(=O)c1sc(NC(=O)c2ccccc2)c(C(=O)OC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N17 compound treatment 0.266 0.00788 0.42 0.4234 1.0 1663793 TimTec1_002415 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N18 compound treatment 0.272 0.0139 0.75 0.7458 1.0 3083249 TimTec1_002416 COc1ccc(/C=N/c2nonc2N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N19 compound treatment 0.259 8.79E-4 0.05 0.0472 1.0 1431956 TimTec1_002417 O=C(Nn1nnnc1Nc2ccccc2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N20 compound treatment 0.434 0.176 9.45 9.4514 1.0 3210540 TimTec1_002418 O=C(NCCSc1ccccc1)C2CCCN2S(=O)(=O)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N21 compound treatment 0.447 0.189 10.15 10.15 1.0 1438435 TimTec1_002419 CC(C)(C)N1C(=O)c2ccc(cc2C1=O)C(=O)Nc3nccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N22 compound treatment 0.258 -1.21E-4 -0.01 -0.0065 -1.0 3083251 TimTec1_002420 Cc1nn(Cc2ccc(o2)C(=O)n3cc(Cl)cn3)c(C)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N23 mock treatment 0.251 -0.00712 -0.38 -0.3827 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 N24 mock treatment 0.248 -0.0101 -0.54 -0.5439 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O01 compound treatment 0.249 -0.00912 -0.49 -0.4902 -1.0 3210541 TimTec1_002421 COC(=O)c1cccc(NC(=S)N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O02 compound treatment 0.253 -0.00512 -0.28 -0.2752 -1.0 3210542 TimTec1_002422 CCC(C)OC(=O)C1CC=CCC1C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O03 compound treatment 0.244 -0.0141 -0.76 -0.7588 -1.0 1368916 TimTec1_002423 CC(C)(C)S(=O)(=O)c1ccc(s1)S(=O)(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O04 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 3083253 TimTec1_002424 Oc1ccccc1c2cc(nc(n2)c3ccccc3)c4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O05 compound treatment 0.419 0.161 8.65 8.6453 1.0 3210543 TimTec1_002425 Oc1ccc(/C=C/2\N=C(N(C2=O)c3nc4cc(Cl)c(F)cc4s3)c5ccccc5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O06 compound treatment 0.271 0.0129 0.69 0.6921 1.0 1018518 TimTec1_002426 NC(=O)Nc1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O07 compound treatment 0.274 0.0159 0.85 0.8533 1.0 3210544 TimTec1_002427 Cc1ccc2nc([nH]c2c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O08 compound treatment 0.367 0.109 5.85 5.8509 1.0 3210545 TimTec1_002428 Cc1ccc(cc1/N=C/c2cc(Br)ccc2O)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O09 compound treatment 0.305 0.0469 2.52 2.5192 1.0 1303670 TimTec1_002429 OCCSc1nc2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O10 compound treatment 0.354 0.0959 5.15 5.1523 1.0 1421938 TimTec1_002430 O=S(=O)(N1CCC(Cc2ccccc2)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O11 compound treatment 0.255 -0.00312 -0.17 -0.1677 -1.0 3083599 TimTec1_002431 CCn1ccc(C(C)C)c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O12 compound treatment 0.357 0.0989 5.31 5.3135 1.0 1392594 TimTec1_002432 CCOC(=O)c1cnc2ccc(OCC)cc2c1NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O13 compound treatment 0.622 0.364 19.55 19.5541 1.0 1448583 TimTec1_002433 CC1=NN(C(=O)CSc2nc3ccccc3s2)C(C)(O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O14 compound treatment 0.329 0.0709 3.81 3.8089 1.0 3210546 TimTec1_002434 COc1ccc(cc1OC)C(=O)NCCOc2cc(C)cc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O15 compound treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1920603 TimTec1_002435 CC1CCN(CC1)C(=O)Nc2ccccc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O16 compound treatment 0.335 0.0769 4.13 4.1313 1.0 1864261 TimTec1_002436 CCC(=O)Oc1ccc(/C=C/c2ccccc2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O17 compound treatment 0.404 0.146 7.84 7.8392 1.0 3210547 TimTec1_002437 Brc1ccc(cc1)C(=O)CSC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O18 compound treatment 0.27 0.0119 0.64 0.6383 1.0 1208412 TimTec1_002438 CC(C)C(=O)NC1CCCCCCCCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O19 compound treatment 0.511 0.253 13.59 13.5892 1.0 1373698 TimTec1_002439 N#Cc1nc(oc1NCc2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O20 compound treatment 0.512 0.254 13.64 13.6429 1.0 3210548 TimTec1_002440 Clc1ccc(OCCCC(=O)NCC2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O21 compound treatment 0.281 0.0229 1.23 1.2295 1.0 1545717 TimTec1_002441 O=C(Nc1ccccc1)C2CC=CCC2C(=O)OCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O22 compound treatment 0.324 0.0659 3.54 3.5402 1.0 3083601 TimTec1_002442 CCC(C)NC(=O)Nc1ccc(C)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O23 mock treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 O24 mock treatment 0.254 -0.00412 -0.22 -0.2215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P01 compound treatment 0.255 -0.00312 -0.17 -0.1677 -1.0 3210549 TimTec1_002443 COc1ccc(CCNC(=O)NC(C)(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P02 compound treatment 0.351 0.0929 4.99 4.9911 1.0 3083602 TimTec1_002444 Cc1ccc(cc1)S(=O)(=O)c2no[n+]([O-])c2S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P03 compound treatment 0.409 0.151 8.11 8.1079 1.0 3210664 TimTec1_002445 Clc1ccc(NC(=O)c2ccc(CSC3=NCCS3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P04 compound treatment 0.26 0.00188 0.1 0.101 1.0 1549117 TimTec1_002446 CN(C1CC(C)(C)N(O)C(C)(C)C1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P05 compound treatment 0.247 -0.0111 -0.6 -0.5976 -1.0 3210665 TimTec1_002447 Cc1ccc(/C(=N\O)/N)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P06 compound treatment 0.252 -0.00612 -0.33 -0.3289 -1.0 1268004 TimTec1_002448 CN(C1CC(C)(C)NC(C)(C)C1)C(=O)c2ccc(cc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P07 compound treatment 0.265 0.00688 0.37 0.3697 1.0 3083603 TimTec1_002449 NNC(=O)c1nnn(c1CNc2ccccc2)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P08 compound treatment 0.25 -0.00812 -0.44 -0.4364 -1.0 1521216 TimTec1_002450 CC1(C)CC(CC(C)(C)N1)NC(=O)NC(=O)c2c(F)cccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P09 compound treatment 0.282 0.0239 1.28 1.2832 1.0 1778355 TimTec1_002451 CC(C)(C)C(=O)Nc1c[nH]c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P10 compound treatment 0.29 0.0319 1.71 1.7131 1.0 3210666 TimTec1_002452 Cc1cc(C)c(C#N)c(SCC(=O)C(C)(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P11 compound treatment 0.301 0.0429 2.3 2.3042 1.0 1283021 TimTec1_002453 OC(=O)c1ccccc1NC(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P12 compound treatment 0.437 0.179 9.61 9.6126 1.0 3210667 TimTec1_002454 C(=N/c1cccc(\N=C\c2ccco2)n1)\c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P13 compound treatment 0.553 0.295 15.85 15.8462 1.0 3210668 TimTec1_002455 COC(=O)c1cccc(NC(=O)/C=C/c2ccc3OCOc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P14 compound treatment 0.245 -0.0131 -0.71 -0.7051 -1.0 3083604 TimTec1_002456 Cc1sc2ncnc(Sc3ncnc4sc(C)c(C)c34)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P15 compound treatment 0.453 0.195 10.47 10.4724 1.0 1287584 TimTec1_002457 CCOC(=O)c1ccc(NC(=O)C(Sc2ccccc2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P16 compound treatment 0.275 0.0169 0.91 0.907 1.0 3083605 TimTec1_002458 COC(=O)c1ccc(Cl)cc1OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P17 compound treatment 0.241 -0.0171 -0.92 -0.9201 -1.0 1716804 TimTec1_002459 CC1CC(O)(CC(O)(c2ccccc2)c3ccccc3)C(C)CN1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P18 compound treatment 0.253 -0.00512 -0.28 -0.2752 -1.0 3083606 TimTec1_002460 Cc1cccc(N2C(=O)/C(=C\3/C(=O)N(CC(=O)O)c4ccccc34)/SC2=S)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P19 compound treatment 0.401 0.143 7.68 7.678 1.0 3210669 TimTec1_002461 CC1CCc2c(C#N)c(/N=C/C=C/c3ccccc3)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P20 compound treatment 0.298 0.0399 2.14 2.143 1.0 1689508 TimTec1_002462 CC(C)(C)c1ccc(CNC(=O)C2CCCN2S(=O)(=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P21 compound treatment 0.308 0.0499 2.68 2.6804 1.0 3083607 TimTec1_002463 CC(C)(CNC(=O)c1ccccc1Cl)CNC2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P22 compound treatment 0.371 0.113 6.07 6.0659 1.0 1611856 TimTec1_002464 Cc1ccc(CC(=O)[C@@H]2[C@@H](c3ccoc3)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P23 mock treatment 0.231 -0.0271 -1.46 -1.4574 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2069 P24 mock treatment 0.249 -0.00912 -0.49 -0.4902 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A01 compound treatment 0.243 -0.00523 -0.28 -0.2808 -1.0 1440335 TimTec1_002465 COc1ccc2N(C(=O)CN3C(=O)CCC3=O)C(C)(C)C=C(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A02 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 3210671 TimTec1_002466 Oc1ccccc1/C=N/c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A03 compound treatment 0.327 0.0788 4.23 4.2332 1.0 1235611 TimTec1_002467 CCSc1nc2ccc(NC(=O)c3ccccc3C(=O)O)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A04 compound treatment 0.276 0.0278 1.49 1.4925 1.0 3210672 TimTec1_002468 CC(NC(=O)/C=C/c1cccc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A05 compound treatment 0.272 0.0238 1.28 1.2776 1.0 3210673 TimTec1_002469 C[S+](C)c1c(O)n(CCc2ccc(F)cc2)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A06 compound treatment 0.25 0.00177 0.1 0.0953 1.0 3083610 TimTec1_002470 COC(=O)COc1c(C)cc(Br)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A07 compound treatment 0.476 0.228 12.24 12.2401 1.0 3210674 TimTec1_002471 Oc1cc(=O)n(n2c(=O)cc(O)n(c3ccccc3)c2=S)c(=S)n1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A08 compound treatment 0.218 -0.0302 -1.62 -1.6243 -1.0 1664815 TimTec1_002472 Cn1c(Cl)c(CN)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A09 compound treatment 0.274 0.0258 1.39 1.3851 1.0 3083613 TimTec1_002473 CCOC(=O)c1cc(C(=O)c2ccc(Cl)cc2)n3c1ccc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A10 compound treatment 0.36 0.112 6.01 6.0065 1.0 3210675 TimTec1_002474 COc1ccc2ccccc2c1/C=N/c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A11 compound treatment 0.287 0.0388 2.08 2.0836 1.0 3210676 TimTec1_002475 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C/NCCC3=CCCCC3)/C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A12 compound treatment 0.292 0.0438 2.35 2.3523 1.0 3083616 TimTec1_002476 CCn1c2ccccc2c3cc(/C=N/c4cccc(C#N)c4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A13 compound treatment 0.233 -0.0152 -0.82 -0.8182 -1.0 1250862 TimTec1_002477 CC(N1C(=O)c2ccccc2C1=O)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A14 compound treatment 0.258 0.00977 0.53 0.5252 1.0 1382898 TimTec1_002478 NC(=O)c1cccc(c1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A15 compound treatment 0.289 0.0408 2.19 2.1911 1.0 3210677 TimTec1_002479 Cc1ccc(C(=O)c2ccn(n2)C(=O)c3ccc(F)cc3)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A16 compound treatment 0.322 0.0738 3.96 3.9645 1.0 3083617 TimTec1_002480 COc1cc(OC)c(/C=N/O)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A17 compound treatment 0.335 0.0868 4.66 4.6631 1.0 3210678 TimTec1_002481 Clc1cc(NC(=O)C2CC2)ccc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A18 compound treatment 0.37 0.122 6.54 6.5439 1.0 3210679 TimTec1_002482 Cc1c(Cc2ccccc2)sc(/N=C/c3ccc4ccccc4c3)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A19 compound treatment 0.303 0.0548 2.94 2.9435 1.0 3083619 TimTec1_002483 CCOc1ccc(/N=C\2/C(=O)Nc3ccc(C)c(Br)c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A20 compound treatment 0.332 0.0838 4.5 4.5019 1.0 1596328 TimTec1_002484 Oc1ccc(cc1)C2N(CCN2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A21 compound treatment 0.302 0.0538 2.89 2.8897 1.0 3210680 TimTec1_002485 CCN(CC)c1ccc(/C=N/c2ccc(Br)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A22 compound treatment 0.28 0.0318 1.71 1.7075 1.0 3210681 TimTec1_002486 CCc1c(O)nc(SCC(=O)NC(C)(C)C)n(c2ccc(F)cc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A23 mock treatment 0.27 0.0218 1.17 1.1701 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 A24 mock treatment 0.289 0.0408 2.19 2.1911 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B01 compound treatment 0.247 -0.00123 -0.07 -0.0659 -1.0 3210682 TimTec1_002487 CCc1n[nH]c(=O)n1Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B02 compound treatment 0.563 0.315 16.92 16.9153 1.0 1134528 TimTec1_002488 Clc1cccc(NC(=O)NCCN2Cc3ccccc3C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B03 compound treatment 0.282 0.0338 1.81 1.815 1.0 1695505 TimTec1_002489 COC(=O)c1ccccc1NC(=O)c2c(C)nc3ccccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B04 compound treatment 0.264 0.0158 0.85 0.8477 1.0 1061354 TimTec1_002490 OC(=O)CCCN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B05 compound treatment 0.273 0.0248 1.33 1.3313 1.0 3210683 TimTec1_002491 C/C(=N\n1cnnc1)/c2ccc(cc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B06 compound treatment 0.28 0.0318 1.71 1.7075 1.0 1660739 TimTec1_002492 Clc1cccc(NC(=O)C2CN(Cc3ccccc3)C(=O)C2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B07 compound treatment 0.326 0.0778 4.18 4.1794 1.0 1742832 TimTec1_002493 CCOC(=O)N(C)CCc1cc2OCOc2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B08 compound treatment 0.462 0.214 11.49 11.4878 1.0 3083672 TimTec1_002494 Cc1ccc2nc(=S)nc(c3ccccc3)n2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B09 compound treatment 0.312 0.0638 3.43 3.4271 1.0 3210684 TimTec1_002495 N=C1S/C(=C\2/C(=O)NN(C2=O)c3ccccc3)/SC=C1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B10 compound treatment 0.337 0.0888 4.77 4.7705 1.0 1574189 TimTec1_002496 COc1ccc(cc1)C(C#N)N2N=C(C)CC2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B11 compound treatment 0.416 0.168 9.02 9.0158 1.0 3083674 TimTec1_002497 O=C1NN=C(CC(N1)c2ccco2)c3cc4ccccc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B12 compound treatment 0.393 0.145 7.78 7.7799 1.0 1539134 TimTec1_002498 Sc1nc2cc(ccc2s1)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B13 compound treatment 0.279 0.0308 1.65 1.6537 1.0 3083676 TimTec1_002499 OCc1cn(nn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B14 compound treatment 0.368 0.12 6.44 6.4364 1.0 1459359 TimTec1_002500 Clc1ccc(CCN2CC(CC2=O)C(=O)OCC(=O)c3ccc(Cl)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B15 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1402941 TimTec1_002501 CN(C)Cc1nnnn1CCn2nnnc2CN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B16 compound treatment 0.408 0.16 8.59 8.5859 1.0 3210801 TimTec1_002502 Cc1ccc(C(=O)COC(=O)c2ccc(cc2)n3cnnn3)c(C)c1.Cc1ccc(C)c(c1)C(=O)COC(=O)c2ccc(cc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B17 compound treatment 0.357 0.109 5.85 5.8453 1.0 3083678 TimTec1_002503 COC(=O)c1c(C)c(C)[nH]c(=O)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B18 compound treatment 0.36 0.112 6.01 6.0065 1.0 1544714 TimTec1_002504 CCOc1ccc(c2ccccc12)S(=O)(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B19 compound treatment 0.275 0.0268 1.44 1.4388 1.0 1721791 TimTec1_002505 CC(C)C(C)(NC(=O)c1cccnc1Oc2ccc(Cl)cc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B20 compound treatment 0.287 0.0388 2.08 2.0836 1.0 1358324 TimTec1_002506 CCOC(=O)CN(C)c1nc(cs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B21 compound treatment 0.356 0.108 5.79 5.7916 1.0 1160634 TimTec1_002507 O=C(NCc1nc(cs1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B22 compound treatment 0.483 0.235 12.62 12.6163 1.0 1033354 TimTec1_002508 O=C(Nc1cccc(c1)C2=NCCN2)Nc3cccc(c3)C4=NCCN4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B23 mock treatment 0.256 0.00777 0.42 0.4178 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 B24 mock treatment 0.255 0.00677 0.36 0.364 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C01 compound treatment 0.461 0.213 11.43 11.434 1.0 1317591 TimTec1_002509 Brc1ccccc1OCc2ccc(o2)C(=O)Nc3ccc(I)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C02 compound treatment 0.266 0.0178 0.96 0.9551 1.0 3210802 TimTec1_002510 Oc1ccc(Br)cc1/C=N/CCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C03 compound treatment 0.296 0.0478 2.57 2.5673 1.0 3083683 TimTec1_002511 COC(=O)c1ccc(cc1)n2nnnc2SCC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C04 compound treatment 0.433 0.185 9.93 9.9294 1.0 3210803 TimTec1_002512 O=C(Nc1nccs1)/C=C/c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C05 compound treatment 0.271 0.0228 1.22 1.2238 1.0 1542712 TimTec1_002513 CCOc1ccc(NC(=O)CSc2nnnn2CC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C06 compound treatment 0.233 -0.0152 -0.82 -0.8182 -1.0 3083686 TimTec1_002514 COc1cc(/C=N/O)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C07 compound treatment 0.501 0.253 13.58 13.5836 1.0 1452827 TimTec1_002515 O=C(CSc1nc2scc(c3cccs3)c2c(=O)n1c4ccccc4)NCc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C08 compound treatment 0.235 -0.0132 -0.71 -0.7107 -1.0 1593834 TimTec1_002516 OCc1ccccc1CN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C09 compound treatment 0.357 0.109 5.85 5.8453 1.0 1361213 TimTec1_002517 COC(=O)c1cc(c(C)o1)c2cncnc2c3ccc(OC)c(C)c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C10 compound treatment 0.411 0.163 8.75 8.7471 1.0 3210804 TimTec1_002518 COc1ccc2ccccc2c1/C=N/c3cccc(CO)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C11 compound treatment 0.26 0.0118 0.63 0.6327 1.0 1240365 TimTec1_002519 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C12 compound treatment 0.259 0.0108 0.58 0.579 1.0 3083730 TimTec1_002520 Cc1cc(C)cc(/N=C/c2ccc(C#N)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C13 compound treatment 0.439 0.191 10.25 10.2518 1.0 3083732 TimTec1_002521 N/C(=C\C(=O)c1ccc(Br)cc1)/C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C14 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 3210805 TimTec1_002522 COc1cc(/C=N/c2cc(C)ccc2C)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C15 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 3210806 TimTec1_002523 CN1CCN(CC1)C(=O)c2ccccc2NC(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C16 compound treatment 0.267 0.0188 1.01 1.0089 1.0 1638681 TimTec1_002524 Ic1ccc(NC(=O)c2ccccc2C(=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C17 compound treatment 0.257 0.00877 0.47 0.4715 1.0 3083735 TimTec1_002525 Cc1ccsc1/C=N/c2c(C)cc(C)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C18 compound treatment 0.26 0.0118 0.63 0.6327 1.0 3210807 TimTec1_002526 CC(=O)N/C(=C/c1ccccc1)/C(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C19 compound treatment 0.407 0.159 8.53 8.5322 1.0 3210808 TimTec1_002527 CCn1c2ccccc2c3cc(/C=N/c4ccc(OC)cc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C20 compound treatment 0.467 0.219 11.76 11.7565 1.0 3083737 TimTec1_002528 COc1cc(NC(=O)c2cccc(Br)c2)nc(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C21 compound treatment 0.298 0.0498 2.67 2.6748 1.0 3210809 TimTec1_002529 COc1cc(/C=N/c2ccc(Br)c(Cl)c2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C22 compound treatment 0.277 0.0288 1.55 1.5463 1.0 3083739 TimTec1_002530 CC1=C(CNC(=S)N1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C23 mock treatment 0.251 0.00277 0.15 0.1491 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 C24 mock treatment 0.26 0.0118 0.63 0.6327 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D01 compound treatment 0.249 7.74E-4 0.04 0.0416 1.0 3210810 TimTec1_002531 CCCc1nncn1NC(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D02 compound treatment 0.317 0.0688 3.7 3.6958 1.0 1545647 TimTec1_002532 CCC1=NCC(=O)Nc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D03 compound treatment 0.496 0.248 13.31 13.3149 1.0 3210811 TimTec1_002533 O=C/1Nc2ccccc2\C1=N\N3C(=O)CC(=O)CC3=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D04 compound treatment 0.556 0.308 16.54 16.5391 1.0 1629795 TimTec1_002534 O=C(COc1ccccc1C#N)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D05 compound treatment 0.31 0.0618 3.32 3.3196 1.0 1595606 TimTec1_002535 Cc1cc(C)n(CNc2c(C)n(C)n(c3ccccc3)c2=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D06 compound treatment 0.257 0.00877 0.47 0.4715 1.0 1277145 TimTec1_002536 CC1=NN(C(=O)Cc2ccccc2)C(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D07 compound treatment 0.329 0.0808 4.34 4.3406 1.0 3210812 TimTec1_002537 CC(=O)OC1=NN(N(=C1)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D08 compound treatment 0.415 0.167 8.96 8.9621 1.0 3210813 TimTec1_002538 CCCc1ccc(OCCNC(=O)c2ccc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D09 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1241793 TimTec1_002539 CCOC(=O)Cn1c2CCC(Cc2sc1=N)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D10 compound treatment 0.254 0.00577 0.31 0.3103 1.0 1587827 TimTec1_002540 OC(=O)CC1(CC(=O)NCc2ccc3OCOc3c2)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D11 compound treatment 0.266 0.0178 0.96 0.9551 1.0 3083745 TimTec1_002541 Clc1ccc(CNC(=C(C#N)C#N)Nc2ccccc2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D12 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1378435 TimTec1_002542 CCCC(O)(CCC)C(=O)NN1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D13 compound treatment 0.3 0.0518 2.78 2.7822 1.0 1537190 TimTec1_002543 CCCC(=O)n1c(=O)oc2cc(Br)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D14 compound treatment 0.294 0.0458 2.46 2.4598 1.0 3083789 TimTec1_002544 COc1ccc(C#N)c(c1)S(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D15 compound treatment 0.241 -0.00723 -0.39 -0.3883 -1.0 3241 TimTec1_002545 CN1CCCN=C1/C=C/c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D16 compound treatment 0.251 0.00277 0.15 0.1491 1.0 3083792 TimTec1_002546 CNc1nc(Nc2ccc(OC(F)(F)F)cc2)nc(OCC(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D17 compound treatment 0.268 0.0198 1.06 1.0626 1.0 1551509 TimTec1_002547 C(N1CCOCC1)c2ccc(cc2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D18 compound treatment 0.26 0.0118 0.63 0.6327 1.0 3210815 TimTec1_002548 CCC1(C)OC(=O)N2CCc3ccccc3C21C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D19 compound treatment 0.25 0.00177 0.1 0.0953 1.0 1026666 TimTec1_002549 Clc1ccccc1NC(=O)Nc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D20 compound treatment 0.257 0.00877 0.47 0.4715 1.0 3083794 TimTec1_002550 Oc1cc(n[nH]1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D21 compound treatment 0.255 0.00677 0.36 0.364 1.0 1273445 TimTec1_002551 CC(=O)Nc1cc2OCCOc2cc1C(=O)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D22 compound treatment 0.257 0.00877 0.47 0.4715 1.0 1411171 TimTec1_002552 OCCN1CCN(CC1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D23 mock treatment 0.243 -0.00523 -0.28 -0.2808 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 D24 mock treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E01 compound treatment 0.235 -0.0132 -0.71 -0.7107 -1.0 1153857 TimTec1_002553 COc1ccc(NC(=S)N2CCN(C)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E02 compound treatment 0.404 0.156 8.37 8.371 1.0 1699449 TimTec1_002554 S=C(Nc1sc2CCCc2c1C#N)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E03 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1502764 TimTec1_002555 Cc1cc(C)n(n1)C(Nc2cc(C)ccn2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E04 compound treatment 0.247 -0.00123 -0.07 -0.0659 -1.0 1627110 TimTec1_002556 OCc1ccccc1CNc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E05 compound treatment 0.254 0.00577 0.31 0.3103 1.0 1382760 TimTec1_002557 CCC(=O)Nc1nc(NC(=O)CC)c2ncn(C(=O)CC)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E06 compound treatment 0.25 0.00177 0.1 0.0953 1.0 1126108 TimTec1_002558 COc1ccc(CCNc2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E07 compound treatment 0.302 0.0538 2.89 2.8897 1.0 3083800 TimTec1_002559 COc1ccc(cc1)C2=C3NN=C(N)N3NN2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E08 compound treatment 0.269 0.0208 1.12 1.1164 1.0 1594522 TimTec1_002560 CNCc1cc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E09 compound treatment 0.257 0.00877 0.47 0.4715 1.0 3210930 TimTec1_002561 COc1ccc(c(O)c1)c2ncnc(c2c3cscn3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E10 compound treatment 0.325 0.0768 4.13 4.1257 1.0 3083802 TimTec1_002562 CCOC(=O)c1ccc(/N=C/c2ccc3ccccc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E11 compound treatment 0.425 0.177 9.5 9.4995 1.0 1258628 TimTec1_002563 NS(=O)(=O)c1ccc(CCNC(=O)C(Sc2ccccc2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E12 compound treatment 0.256 0.00777 0.42 0.4178 1.0 3083804 TimTec1_002564 CCN(CC)c1ccc(/C=N/c2cc(C)cc(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E13 compound treatment 0.33 0.0818 4.39 4.3944 1.0 3210931 TimTec1_002565 Cc1ccc(O)c(c1)c2cc(no2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E14 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1565284 TimTec1_002566 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E15 compound treatment 0.316 0.0678 3.64 3.642 1.0 1532411 TimTec1_002567 O=C(Nc1ccccc1)Nc2ccc(cc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E16 compound treatment 0.348 0.0998 5.36 5.3617 1.0 1209164 TimTec1_002568 N#Cc1ccc(cc1)C2N(CCN2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E17 compound treatment 0.258 0.00977 0.53 0.5252 1.0 1709264 TimTec1_002569 OC(c1cccs1)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E18 compound treatment 0.389 0.141 7.56 7.5649 1.0 3210932 TimTec1_002570 CCn1c2ccccc2c3cc(/C=N/c4ccc(C)cc4O)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E19 compound treatment 0.336 0.0878 4.72 4.7168 1.0 3083808 TimTec1_002571 FC(F)(F)Oc1ccc(/N=C/c2ccc[nH]2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E20 compound treatment 0.298 0.0498 2.67 2.6748 1.0 1012470 TimTec1_002572 COc1ccc(CNC2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E21 compound treatment 0.396 0.148 7.94 7.9411 1.0 3210933 TimTec1_002573 COC(=O)c1ccc(/N=C/c2ccc(Br)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E22 compound treatment 0.287 0.0388 2.08 2.0836 1.0 1473837 TimTec1_002574 O=C(NCc1ccco1)C2CCCN2S(=O)(=O)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E23 mock treatment 0.253 0.00477 0.26 0.2566 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 E24 mock treatment 0.256 0.00777 0.42 0.4178 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F01 compound treatment 0.281 0.0328 1.76 1.7612 1.0 1161969 TimTec1_002575 CN(C)c1ccc(cc1)C2ON2[C@H]3CC[C@H](O)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F02 compound treatment 0.252 0.00377 0.2 0.2028 1.0 1195693 TimTec1_002576 COc1ccc(cc1OC)C2OC(=O)C(=C(O)C2(C)C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F03 compound treatment 0.45 0.202 10.84 10.8429 1.0 3210934 TimTec1_002577 CN(C)c1ccc(/C=C(/NC(=O)c2ccccc2)\C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F04 compound treatment 0.335 0.0868 4.66 4.6631 1.0 1326441 TimTec1_002578 Nc1nonc1OCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F05 compound treatment 0.266 0.0178 0.96 0.9551 1.0 3210935 TimTec1_002579 Clc1ccc(/C=N/N2C(=O)CNC2=O)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F06 compound treatment 0.295 0.0468 2.51 2.5135 1.0 3083845 TimTec1_002580 CCOC(=O)c1cc(C)[nH]c(=S)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F07 compound treatment 0.241 -0.00723 -0.39 -0.3883 -1.0 3210936 TimTec1_002581 CCOC(=O)C1C(C)NC(=O)N=C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F08 compound treatment 0.356 0.108 5.79 5.7916 1.0 1507322 TimTec1_002582 COc1ccc(cc1OC)C(=O)CSc2nc(N)cc(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F09 compound treatment 0.32 0.0718 3.86 3.857 1.0 1564107 TimTec1_002583 Oc1ccccc1SCC(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F10 compound treatment 0.254 0.00577 0.31 0.3103 1.0 1190430 TimTec1_002584 OC(=O)c1ccccc1c2nnn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F11 compound treatment 0.253 0.00477 0.26 0.2566 1.0 3210937 TimTec1_002585 Cc1ccnc(NS(=O)(=O)c2ccc(/N=C/3\SCC(=O)N3CC=C)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F12 compound treatment 0.265 0.0168 0.9 0.9014 1.0 3210938 TimTec1_002586 COC(=O)C1=CN(Cc2ccc(Cl)cc2)C=C(C1c3cccs3)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F13 compound treatment 0.547 0.299 16.06 16.0555 1.0 1386655 TimTec1_002587 COc1ccc(OC)c(c1)C(=O)COc2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F14 compound treatment 0.252 0.00377 0.2 0.2028 1.0 1502288 TimTec1_002588 Nc1nc(=O)n(CCC#N)cc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F15 compound treatment 0.365 0.117 6.28 6.2752 1.0 1508658 TimTec1_002589 CSC1=C(C#N)C2(CCCCC2)C3=C(CCC3)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F16 compound treatment 0.28 0.0318 1.71 1.7075 1.0 1232692 TimTec1_002590 Cc1cccc(C)c1NC(=O)C(NC(=O)c2ccc(cc2)n3cnnn3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F17 compound treatment 0.29 0.0418 2.24 2.2449 1.0 3083851 TimTec1_002591 COc1ccc(Cl)cc1C(=O)NN2C(=CC(C)(C)NC2=S)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F18 compound treatment 0.243 -0.00523 -0.28 -0.2808 -1.0 3210939 TimTec1_002592 FC(F)(F)C1(N=C(OC(=N1)N2CCOCC2)N3CCOCC3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F19 compound treatment 0.244 -0.00423 -0.23 -0.2271 -1.0 3083853 TimTec1_002593 NC1=NC(=O)C(CC(=O)O)CS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F20 compound treatment 0.398 0.15 8.05 8.0486 1.0 1554458 TimTec1_002594 CCOC(=O)C1(CCN(CCC(=O)Nc2ccc(cc2)C(=O)OC)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F21 compound treatment 0.268 0.0198 1.06 1.0626 1.0 1231612 TimTec1_002595 COc1ccc(cc1)C2C(C)C3(O)CC(C#N)(C(=O)N3)C2(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F22 compound treatment 0.463 0.215 11.54 11.5415 1.0 1368021 TimTec1_002596 CC(=O)N(CCOc1ccccc1)CCOc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F23 mock treatment 0.253 0.00477 0.26 0.2566 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 F24 mock treatment 0.241 -0.00723 -0.39 -0.3883 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G01 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1248844 TimTec1_002597 Cc1ccc(o1)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G02 compound treatment 0.244 -0.00423 -0.23 -0.2271 -1.0 3210940 TimTec1_002598 S=C(Nc1ccccc1)Nc2cccc(C#N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G03 compound treatment 0.445 0.197 10.57 10.5742 1.0 1385961 TimTec1_002599 Cc1ccc(cc1C)C(=O)COC(=O)c2ccc(cc2)c3nnc(o3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G04 compound treatment 0.387 0.139 7.46 7.4574 1.0 1301988 TimTec1_002600 Brc1c(OCC(=O)NCc2ccccc2)ccc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G05 compound treatment 0.459 0.211 11.33 11.3266 1.0 3210941 TimTec1_002601 O=C1CNC(=O)N1/N=C/2\C(=O)Nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G06 compound treatment 0.239 -0.00923 -0.5 -0.4958 -1.0 3083899 TimTec1_002602 COc1ccc(CCNCc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G07 compound treatment 0.261 0.0128 0.69 0.6865 1.0 3083901 TimTec1_002603 Cc1c(C#N)c(=O)n(nc1C(=O)O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G08 compound treatment 0.253 0.00477 0.26 0.2566 1.0 3210942 TimTec1_002604 Cn1ccnc1C(O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G09 compound treatment 0.3 0.0518 2.78 2.7822 1.0 3210943 TimTec1_002605 CCCN1C(=O)/C(=C\2/C(=O)N(CC=C)c3ccccc23)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G10 compound treatment 0.258 0.00977 0.53 0.5252 1.0 3083904 TimTec1_002606 NC(=O)c1cccc(/N=C/c2ccc3ccccc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G11 compound treatment 0.282 0.0338 1.81 1.815 1.0 3210944 TimTec1_002607 CCOc1ccccc1/C=N/c2ccc(cc2)S(=O)(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G12 compound treatment 0.239 -0.00923 -0.5 -0.4958 -1.0 3083906 TimTec1_002608 Cc1ccc(C)c(/N=C/c2ccc(C#N)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G13 compound treatment 0.22 -0.0282 -1.52 -1.5168 -1.0 3210945 TimTec1_002609 Oc1ccccc1c2cc(n(n2)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G14 compound treatment 0.306 0.0578 3.1 3.1047 1.0 3083907 TimTec1_002610 Oc1c(Cl)cc(Cl)cc1/C=N/c2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G15 compound treatment 0.236 -0.0122 -0.66 -0.657 -1.0 1229191 TimTec1_002611 Nc1ccc(cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G16 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 1298485 TimTec1_002612 C=CCC(CC=C)(NC(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G17 compound treatment 0.396 0.148 7.94 7.9411 1.0 3210946 TimTec1_002613 CSc1ccc(/C=N/c2ccc(Nc3ccccc3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G18 compound treatment 0.287 0.0388 2.08 2.0836 1.0 3210947 TimTec1_002614 Cc1[nH]c2ccccc2c1/C=N/c3ccc(Cl)cc3C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G19 compound treatment 0.312 0.0638 3.43 3.4271 1.0 3083909 TimTec1_002615 COC(=O)CSc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G20 compound treatment 0.26 0.0118 0.63 0.6327 1.0 1173404 TimTec1_002616 COc1ccc2ccccc2c1C(O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G21 compound treatment 0.312 0.0638 3.43 3.4271 1.0 3083910 TimTec1_002617 CCN(CC)c1ccc(/N=C/c2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G22 compound treatment 0.473 0.225 12.08 12.0789 1.0 3210948 TimTec1_002618 CN1C(=O)/C(=C\c2c(O)c3ccccc3n(C)c2=O)/C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G23 mock treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 G24 mock treatment 0.244 -0.00423 -0.23 -0.2271 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H01 compound treatment 0.249 7.74E-4 0.04 0.0416 1.0 1619414 TimTec1_002619 Cc1cc(no1)c2c(O)c3ccccc3n(C)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H02 compound treatment 0.24 -0.00823 -0.44 -0.442 -1.0 1650607 TimTec1_002620 CC1C(OC(=O)C2(CCCCC2)C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H03 compound treatment 0.246 -0.00223 -0.12 -0.1196 -1.0 1490854 TimTec1_002621 O=COCC1OC(OC=O)C(Nc2ccccc2)C(OC=O)C1OC=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H04 compound treatment 0.425 0.177 9.5 9.4995 1.0 1609235 TimTec1_002622 Fc1ccc(CSc2nc3cccnc3[nH]2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H05 compound treatment 0.315 0.0668 3.59 3.5883 1.0 3211069 TimTec1_002623 C/C(=N\N1C(=O)CC(=O)NC1=S)/c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H06 compound treatment 0.26 0.0118 0.63 0.6327 1.0 3083914 TimTec1_002624 CC1SC(NC1=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H07 compound treatment 0.307 0.0588 3.16 3.1584 1.0 1308303 TimTec1_002625 CCOC(=O)c1cccc(c1)C(=O)NC2=CC(=O)CC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H08 compound treatment 0.463 0.215 11.54 11.5415 1.0 3083916 TimTec1_002626 COc1ccc(cc1)C(=O)c2nocc2C(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H09 compound treatment 0.428 0.18 9.66 9.6607 1.0 1428534 TimTec1_002627 O=c1oc2ccccc2cc1C3=NC(=S)NC(C3)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H10 compound treatment 0.265 0.0168 0.9 0.9014 1.0 1170391 TimTec1_002628 NC(=O)CN1C(=O)c2cccc3cccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H11 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 3211070 TimTec1_002629 S=c1nc(/N=C/c2ccco2)cc(/N=C/c3ccco3)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H12 compound treatment 0.256 0.00777 0.42 0.4178 1.0 1704493 TimTec1_002630 Cc1cc2OC(=C(C#N)C3(C(=O)N(CC(=O)O)c4ccccc43)c2c(=O)o1)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H13 compound treatment 0.431 0.183 9.82 9.8219 1.0 1554929 TimTec1_002631 O=C(Oc1cccnc1)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H14 compound treatment 0.251 0.00277 0.15 0.1491 1.0 1212825 TimTec1_002632 Cc1[nH]c2ccccc2c1CCN3C(=O)CCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H15 compound treatment 0.284 0.0358 1.92 1.9224 1.0 1243289 TimTec1_002633 COC(=O)C1=C(C)N(C(=O)C1)c2ccc(cc2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H16 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1495691 TimTec1_002634 CC(O)(C#CCN1CCCCC1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H17 compound treatment 0.308 0.0598 3.21 3.2121 1.0 1405861 TimTec1_002635 CCN(CC)C(=O)CSc1nc2CCCCc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H18 compound treatment 0.263 0.0148 0.79 0.7939 1.0 3083985 TimTec1_002636 CCc1c(C)nc(N)nc1S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H19 compound treatment 0.239 -0.00923 -0.5 -0.4958 -1.0 1285150 TimTec1_002637 CC1(O)NC(=O)C2(C#N)C(C#N)(C#N)C21c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H20 compound treatment 0.227 -0.0212 -1.14 -1.1406 -1.0 1677097 TimTec1_002638 Cc1nc(C(=O)N)c(N)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H21 compound treatment 0.468 0.22 11.81 11.8102 1.0 1163471 TimTec1_002639 COC(=O)c1ccc(NC(=O)CSc2nccn2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H22 compound treatment 0.251 0.00277 0.15 0.1491 1.0 3083989 TimTec1_002640 Cc1cc(C)n(CNc2nccs2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H23 mock treatment 0.246 -0.00223 -0.12 -0.1196 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 H24 mock treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I01 compound treatment 0.357 0.109 5.85 5.8453 1.0 1611631 TimTec1_002641 O=C(Nc1ccccc1)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I02 compound treatment 0.259 0.0108 0.58 0.579 1.0 1685279 TimTec1_002642 COc1ccc(cc1I)C(=O)Nc2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I03 compound treatment 0.262 0.0138 0.74 0.7402 1.0 1725903 TimTec1_002643 CCOC(=O)C(C)Oc1ccc2oc(=O)cc(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I04 compound treatment 0.45 0.202 10.84 10.8429 1.0 1725678 TimTec1_002644 Cc1ccc(NC(=O)COc2ccc3ccccc3c2Br)cc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I05 compound treatment 0.281 0.0328 1.76 1.7612 1.0 3083992 TimTec1_002645 CN(C)c1ccc(/C=N/N2C(=O)CNC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I06 compound treatment 0.308 0.0598 3.21 3.2121 1.0 3211071 TimTec1_002646 CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1OC(=O)C(O)C(O)C(=O)O[C@H]2C[C@H](C)CC[C@H]2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I07 compound treatment 0.308 0.0598 3.21 3.2121 1.0 1159008 TimTec1_002647 O=C(CSc1ncnc2[nH]cnc12)NCCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I08 compound treatment 0.32 0.0718 3.86 3.857 1.0 3211072 TimTec1_002648 Cc1ccc(/N=C/c2ccc(Br)s2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I09 compound treatment 0.293 0.0448 2.41 2.4061 1.0 1275751 TimTec1_002649 Cc1cccc(c1)N(CC(=O)Nc2ccc3c(c2)oc4ccccc43)S(=O)(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I10 compound treatment 0.278 0.0298 1.6 1.6 1.0 3083996 TimTec1_002650 COc1ccc(/N=C/c2ccc3ccccc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I11 compound treatment 0.433 0.185 9.93 9.9294 1.0 3211073 TimTec1_002651 CC(=O)Nc1ccc(cc1)c2csc(Nc3ccccc3C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I12 compound treatment 0.237 -0.0112 -0.6 -0.6033 -1.0 3083998 TimTec1_002652 Cc1cccc(/C=N/c2cccc(O)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I13 compound treatment 0.304 0.0558 3.0 2.9972 1.0 3083999 TimTec1_002653 O=c1n(OCc2ccccc2)c(SCc3ccccc3)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I14 compound treatment 0.328 0.0798 4.29 4.2869 1.0 3211074 TimTec1_002654 Cc1ccc(/C=N/c2ccc(Oc3ccccc3)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I15 compound treatment 0.47 0.222 11.92 11.9177 1.0 3211075 TimTec1_002655 O=C(Nc1ccccc1)Nc2ccc(cc2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I16 compound treatment 0.263 0.0148 0.79 0.7939 1.0 1270363 TimTec1_002656 Cc1ccc(cc1)S(=O)(=O)NC(CC=C)(CC=C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I17 compound treatment 0.268 0.0198 1.06 1.0626 1.0 3211076 TimTec1_002657 N#Cc1ccc(/C=N/c2cccc3c(\N=C\c4ccc(C#N)cc4)cccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I18 compound treatment 0.321 0.0728 3.91 3.9107 1.0 3084003 TimTec1_002658 NC(=O)c1ccccc1/N=C/c2ccc(O)c(O)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I19 compound treatment 0.312 0.0638 3.43 3.4271 1.0 3211077 TimTec1_002659 Oc1ccc(Br)cc1/C=N/Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I20 compound treatment 0.283 0.0348 1.87 1.8687 1.0 1542526 TimTec1_002660 COc1cc(CNc2ccccc2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I21 compound treatment 0.263 0.0148 0.79 0.7939 1.0 3211078 TimTec1_002661 N#Cc1cccc(/N=C/c2ccc3OCOc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I22 compound treatment 0.271 0.0228 1.22 1.2238 1.0 1646643 TimTec1_002662 CCn1c(=O)c(C(C)Nc2ccco2)c(O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I23 mock treatment 0.256 0.00777 0.42 0.4178 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 I24 mock treatment 0.251 0.00277 0.15 0.1491 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J01 compound treatment 0.39 0.142 7.62 7.6186 1.0 1132674 TimTec1_002663 CCC1=CC(=NC(C)CN1)c2c(O)c3ccccc3n(C)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J02 compound treatment 0.257 0.00877 0.47 0.4715 1.0 3084072 TimTec1_002664 OC(=O)c1ccc2nsnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J03 compound treatment 0.251 0.00277 0.15 0.1491 1.0 1532331 TimTec1_002665 Fc1ccc(cc1)N2C(=S)N=C(CC23C(=O)Nc4ccccc43)c5ccc(F)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J04 compound treatment 0.497 0.249 13.37 13.3686 1.0 3084075 TimTec1_002666 FC(F)(F)c1ccc2n(Cc3ccccc3)c(=O)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J05 compound treatment 0.233 -0.0152 -0.82 -0.8182 -1.0 1654151 TimTec1_002667 O=c1ccn(CN2CCCCC2)c(=O)n1CN3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J06 compound treatment 0.253 0.00477 0.26 0.2566 1.0 1571522 TimTec1_002668 CN1NC2(CCCCC2)N(C1=S)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J07 compound treatment 0.258 0.00977 0.53 0.5252 1.0 3211079 TimTec1_002669 Oc1ccccc1/C=N/c2cc(ccc2O)S(=O)(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J08 compound treatment 0.267 0.0188 1.01 1.0089 1.0 1488051 TimTec1_002670 CC1CN(CCc2ccccc2)CCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J09 compound treatment 0.294 0.0458 2.46 2.4598 1.0 3211080 TimTec1_002671 C/C(=N\Cc1ccccn1)/c2c(O)c3ccccc3n(c4ccccc4)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J10 compound treatment 0.262 0.0138 0.74 0.7402 1.0 3084079 TimTec1_002672 OCCNC(=O)C1=NN=CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J11 compound treatment 0.262 0.0138 0.74 0.7402 1.0 1667994 TimTec1_002673 CC1=NN(C(=O)c2ccco2)C(O)(C1)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J12 compound treatment 0.251 0.00277 0.15 0.1491 1.0 3211081 TimTec1_002674 OC(=O)CCCNC1=NC2(CCCC2)Cc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J13 compound treatment 0.241 -0.00723 -0.39 -0.3883 -1.0 3209107 TimTec1_002675 NC(CCCNC(=N)N)C(=O)O.OC(=O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@@H]12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J14 compound treatment 0.256 0.00777 0.42 0.4178 1.0 1608879 TimTec1_002676 NN(C(=O)C1CCCCC1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J15 compound treatment 0.24 -0.00823 -0.44 -0.442 -1.0 1250350 TimTec1_002677 COc1cc(NC(=O)C)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J16 compound treatment 0.294 0.0458 2.46 2.4598 1.0 1447389 TimTec1_002678 Cn1cnc2n(Cc3ccccc3)c(=O)[nH]c(=S)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J17 compound treatment 0.381 0.133 7.14 7.135 1.0 1466505 TimTec1_002679 COCc1cc(O)n2c3ccccc3nc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J18 compound treatment 0.255 0.00677 0.36 0.364 1.0 1156263 TimTec1_002680 COC(=O)CC1(O)N(C(=CC1=O)c2ccc(C)cc2)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J19 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 1548500 TimTec1_002681 CC1(C)CCCC(C)(C)N1OC(=O)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J20 compound treatment 0.305 0.0568 3.05 3.0509 1.0 3084081 TimTec1_002682 OC1(NN=C2C=Cc3ccccc3N21)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J21 compound treatment 0.251 0.00277 0.15 0.1491 1.0 1276203 TimTec1_002683 CNC(C)c1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J22 compound treatment 0.25 0.00177 0.1 0.0953 1.0 3084083 TimTec1_002684 C(N1CCNCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J23 mock treatment 0.243 -0.00523 -0.28 -0.2808 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 J24 mock treatment 0.243 -0.00523 -0.28 -0.2808 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K01 compound treatment 0.306 0.0578 3.1 3.1047 1.0 3209108 TimTec1_002685 COc1ccc(cc1)C(=O)CSc2nc3cc(C)ccc3cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K02 compound treatment 0.238 -0.0102 -0.55 -0.5495 -1.0 3084085 TimTec1_002686 CCOc1ccc(/C=N/c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K03 compound treatment 0.257 0.00877 0.47 0.4715 1.0 1247383 TimTec1_002687 O=C(CSc1nc2cccnc2[nH]1)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K04 compound treatment 0.24 -0.00823 -0.44 -0.442 -1.0 3084087 TimTec1_002688 COc1cccc(/N=C/c2ccc(O)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K05 compound treatment 0.372 0.124 6.65 6.6514 1.0 3209109 TimTec1_002689 O=C1CNC(=O)N1/N=C/c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K06 compound treatment 0.234 -0.0142 -0.76 -0.7645 -1.0 1409322 TimTec1_002690 OCc1ccccc1CNCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K07 compound treatment 0.261 0.0128 0.69 0.6865 1.0 3209110 TimTec1_002691 CCOC(=O)Cc1c(C)[nH]c2c(c(C)nn2c1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K08 compound treatment 0.255 0.00677 0.36 0.364 1.0 3084090 TimTec1_002692 Cc1ccc(/N=C/c2c[nH]c3ccccc23)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K09 compound treatment 0.279 0.0308 1.65 1.6537 1.0 1411633 TimTec1_002693 CC(NC(=O)c1cc(oc1C)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K10 compound treatment 0.262 0.0138 0.74 0.7402 1.0 3084091 TimTec1_002694 NC(=O)c1ccccc1/N=C/c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K11 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 3209111 TimTec1_002695 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K12 compound treatment 0.265 0.0168 0.9 0.9014 1.0 3084157 TimTec1_002696 Cc1cc(C)cc(/N=C/c2cccc(OCc3ccccc3)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K13 compound treatment 0.246 -0.00223 -0.12 -0.1196 -1.0 3084159 TimTec1_002697 COC(=O)CNC(=O)c1cc[nH]n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K14 compound treatment 0.25 0.00177 0.1 0.0953 1.0 1444507 TimTec1_002698 Cc1ccc(s1)C2N(CCN2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K15 compound treatment 0.257 0.00877 0.47 0.4715 1.0 3084162 TimTec1_002699 FC(F)(F)Oc1ccc(/N=C/c2ccc(Br)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K16 compound treatment 0.326 0.0778 4.18 4.1794 1.0 1914768 TimTec1_002700 C(=N/c1cccc2c(\N=C\c3ccco3)cccc12)\c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K17 compound treatment 0.27 0.0218 1.17 1.1701 1.0 3209112 TimTec1_002701 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)Nc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K18 compound treatment 0.273 0.0248 1.33 1.3313 1.0 3209113 TimTec1_002702 Cc1ccc(/C=N/c2ccccc2OCc3ccccc3)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K19 compound treatment 0.255 0.00677 0.36 0.364 1.0 3084165 TimTec1_002703 N#Cc1cc2CCCc2nc1SCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K20 compound treatment 0.261 0.0128 0.69 0.6865 1.0 1504412 TimTec1_002704 Fc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K21 compound treatment 0.268 0.0198 1.06 1.0626 1.0 3084167 TimTec1_002705 CCOc1ccccc1/C=N/c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K22 compound treatment 0.279 0.0308 1.65 1.6537 1.0 3209114 TimTec1_002706 COc1cccc(c1)C(=O)N2N=C(O)C=CC2=C(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K23 mock treatment 0.26 0.0118 0.63 0.6327 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 K24 mock treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L01 compound treatment 0.311 0.0628 3.37 3.3734 1.0 1454168 TimTec1_002707 COc1cc(OC)nc(n1)C(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L02 compound treatment 0.254 0.00577 0.31 0.3103 1.0 1013845 TimTec1_002708 OC(=O)C1CCN(CC1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L03 compound treatment 0.355 0.107 5.74 5.7378 1.0 3084171 TimTec1_002709 SC1=N(/N=C/2\C(=O)Nc3ccccc23)C(=O)C4C=CC=CC4=N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L04 compound treatment 0.456 0.208 11.17 11.1654 1.0 1202182 TimTec1_002710 NC1=C(C#N)C(=C(C#N)C#N)C(O1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L05 compound treatment 0.252 0.00377 0.2 0.2028 1.0 1265429 TimTec1_002711 CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c3ccc(F)cc3O)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L06 compound treatment 0.26 0.0118 0.63 0.6327 1.0 3084174 TimTec1_002712 COc1ccc(cc1OC)/C(=N/O)/c2nccc3cc(OC)c(OC)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L07 compound treatment 0.428 0.18 9.66 9.6607 1.0 1260243 TimTec1_002713 S=c1nc(c2ccco2)c3c(=S)[nH]c(=S)[nH]c3[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L08 compound treatment 0.241 -0.00723 -0.39 -0.3883 -1.0 1599464 TimTec1_002714 CC1CN(CCC1=O)C2CC(C)(C)NC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L09 compound treatment 0.266 0.0178 0.96 0.9551 1.0 1384770 TimTec1_002715 CN(C)c1ccc(cc1)C2OCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L10 compound treatment 0.246 -0.00223 -0.12 -0.1196 -1.0 1608667 TimTec1_002716 NC(=O)CNC(=O)c1ccc2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L11 compound treatment 0.561 0.313 16.81 16.8078 1.0 3209115 TimTec1_002717 COC(=O)CNS(=O)(=O)Nc1ccc(cc1)c2nc3ccc(C)cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L12 compound treatment 0.469 0.221 11.86 11.8639 1.0 1678540 TimTec1_002718 Clc1ccc2n(CCC(=O)n3c(=O)oc4cc(Cl)ccc34)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L13 compound treatment 0.254 0.00577 0.31 0.3103 1.0 1920767 TimTec1_002719 Cc1cc(c2ccco2)n(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L14 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 3084178 TimTec1_002720 CCOC(=O)Cc1nnn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L15 compound treatment 0.261 0.0128 0.69 0.6865 1.0 3209116 TimTec1_002721 Brc1ccc(cc1)C(=S)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L16 compound treatment 0.276 0.0278 1.49 1.4925 1.0 1354769 TimTec1_002722 CC(C)COC(=O)NCc1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L17 compound treatment 0.26 0.0118 0.63 0.6327 1.0 3209117 TimTec1_002723 Cc1ccc(cc1)[C@H]2[C@@H](C#N)[C@H](C#N)N3CCCN23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L18 compound treatment 0.247 -0.00123 -0.07 -0.0659 -1.0 71735 TimTec1_002724 COc1ccc(CC2NCCc3cc(OC)c(OC)cc23)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L19 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 3084252 TimTec1_002725 CC1(C)OC(=O)N(C1=C)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L20 compound treatment 0.238 -0.0102 -0.55 -0.5495 -1.0 3084253 TimTec1_002726 CC(=O)N1C2CC(C=C2)C1(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L21 compound treatment 0.254 0.00577 0.31 0.3103 1.0 1279868 TimTec1_002727 CCc1ccc(cc1)S(=O)(=O)N2CCC(CC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L22 compound treatment 0.296 0.0478 2.57 2.5673 1.0 1355496 TimTec1_002728 Cc1ccc(CSCC(=O)Nc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L23 mock treatment 0.233 -0.0152 -0.82 -0.8182 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 L24 mock treatment 0.249 7.74E-4 0.04 0.0416 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M01 compound treatment 0.261 0.0128 0.69 0.6865 1.0 1520938 TimTec1_002729 Cn1c2ccccc2c3nn(c4ccccc4)c(=O)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M02 compound treatment 0.259 0.0108 0.58 0.579 1.0 3209118 TimTec1_002730 NS(=O)(=O)c1ccc(/N=C/c2c3ccccc3cc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M03 compound treatment 0.27 0.0218 1.17 1.1701 1.0 3084256 TimTec1_002731 CC(C)(C)c1ccc(OCCNC(=O)c2cccc(Br)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M04 compound treatment 0.531 0.283 15.2 15.1957 1.0 3209119 TimTec1_002732 O=C(Nc1cccc(C#N)c1)/C=C/c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M05 compound treatment 0.308 0.0598 3.21 3.2121 1.0 3084258 TimTec1_002733 Cc1ccc(cc1)N2C(SCC2=O)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M06 compound treatment 0.231 -0.0172 -0.93 -0.9257 -1.0 3209120 TimTec1_002734 C=CCC1(CC=C)CCCCN1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M07 compound treatment 0.36 0.112 6.01 6.0065 1.0 3209121 TimTec1_002735 Cc1nc(NCc2ccco2)c3cc(sc3n1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M08 compound treatment 0.264 0.0158 0.85 0.8477 1.0 3084261 TimTec1_002736 Ic1ccc(/N=C/c2ccc(C#N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M09 compound treatment 0.295 0.0468 2.51 2.5135 1.0 3209238 TimTec1_002737 COc1ccc(OC)c(/C=c/2\sc3nnc(c4ccccc4Cl)n3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M10 compound treatment 0.251 0.00277 0.15 0.1491 1.0 3084262 TimTec1_002738 COc1ccc(/N=C/c2ccccc2OCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M11 compound treatment 0.407 0.159 8.53 8.5322 1.0 3209239 TimTec1_002739 C/C(=N/CCO)/c1c([nH]n(c2nc3ccccc3s2)c1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M12 compound treatment 0.244 -0.00423 -0.23 -0.2271 -1.0 3084263 TimTec1_002740 Cc1ccccc1/C=N/c2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M13 compound treatment 0.239 -0.00923 -0.5 -0.4958 -1.0 3209240 TimTec1_002741 COC(=O)N(C)c1ccccc1C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M14 compound treatment 0.332 0.0838 4.5 4.5019 1.0 3084265 TimTec1_002742 CCCOC(=O)c1ccc(/N=C/c2ccc(C)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M15 compound treatment 0.307 0.0588 3.16 3.1584 1.0 1321825 TimTec1_002743 CC(Oc1ccc(Cl)cc1Cl)C(=O)NN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M16 compound treatment 0.288 0.0398 2.14 2.1374 1.0 3084267 TimTec1_002744 COc1cc(/C=N/c2ccc(cc2)C(=O)c3ccccc3)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M17 compound treatment 0.482 0.234 12.56 12.5625 1.0 1712191 TimTec1_002745 Cc1ccc(cc1I)C(=O)Nc2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M18 compound treatment 0.312 0.0638 3.43 3.4271 1.0 3209241 TimTec1_002746 CCCC(=O)c1ccc(/N=C/c2ccc(Cl)cc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M19 compound treatment 0.33 0.0818 4.39 4.3944 1.0 3084269 TimTec1_002747 Brc1ccc(/C=N/c2ccccc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M20 compound treatment 0.299 0.0508 2.73 2.7285 1.0 1423653 TimTec1_002748 COc1ccc(NC(=O)c2ccc(Cn3cc(Cl)cn3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M21 compound treatment 0.271 0.0228 1.22 1.2238 1.0 3084271 TimTec1_002749 Cc1nn(C(=S)N)c(O)c1C(C(C#N)C#N)c2cccc(Cl)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M22 compound treatment 0.272 0.0238 1.28 1.2776 1.0 3209242 TimTec1_002750 NC(=O)Oc1ccc(I)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M23 mock treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 M24 mock treatment 0.251 0.00277 0.15 0.1491 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N01 compound treatment 0.441 0.193 10.36 10.3593 1.0 3083254 TimTec1_002751 Cc1cc2nnc(c3cccc4OCOc43)n2c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N02 compound treatment 0.255 0.00677 0.36 0.364 1.0 3083257 TimTec1_002752 C/C=C\1/C(C)C(C(=C(N)N1c2ccc(cc2)C(=O)N)C#N)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N03 compound treatment 0.435 0.187 10.04 10.0369 1.0 1231981 TimTec1_002753 Cc1ccc(cc1)C(=O)Cc2nc3ncccc3[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N04 compound treatment 0.276 0.0278 1.49 1.4925 1.0 1274147 TimTec1_002754 Sc1nc(CCN2C(=O)c3ccccc3C2=O)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N05 compound treatment 0.234 -0.0142 -0.76 -0.7645 -1.0 3083260 TimTec1_002755 CC(=S)N1CCN(CC1)C(=S)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N06 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 1517166 TimTec1_002756 Cc1ccccc1N2C(=O)c3ccccc3NC2(C)CC(=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N07 compound treatment 0.362 0.114 6.11 6.114 1.0 1118059 TimTec1_002757 Nn1c(=O)c(Cc2ccco2)n[nH]c1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N08 compound treatment 0.313 0.0648 3.48 3.4808 1.0 1361841 TimTec1_002758 CCOC(=O)C1=C(NC(=S)C(CC=C)(C#N)C1c2cccnc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N09 compound treatment 0.244 -0.00423 -0.23 -0.2271 -1.0 3083263 TimTec1_002759 COC(=O)CNc1cc(C)c(cc1OC)C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N10 compound treatment 0.253 0.00477 0.26 0.2566 1.0 1187305 TimTec1_002760 CCCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N11 compound treatment 0.465 0.217 11.65 11.649 1.0 1455249 TimTec1_002761 CC(=O)Oc1ccc2occ(C(=O)c3ccc(F)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N12 compound treatment 0.247 -0.00123 -0.07 -0.0659 -1.0 1149353 TimTec1_002762 COc1ccc(cc1)C(C#N)N2N=C(C)CC2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N13 compound treatment 0.275 0.0268 1.44 1.4388 1.0 1491757 TimTec1_002763 Clc1cccc(NC(=O)C(NC=O)c2ccccc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N14 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 3209243 TimTec1_002764 OC(=O)[C@@H]1CCCN1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N15 compound treatment 0.236 -0.0122 -0.66 -0.657 -1.0 3083267 TimTec1_002765 OC(=O)CCc1nnc(S)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N16 compound treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1446498 TimTec1_002766 O=C(NC1CCCCCCCCCCC1)c2nc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N17 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 3209244 TimTec1_002767 COc1ccc(cc1)[C@H]2[C@@H](C#N)[C@H](C#N)N3CCCN23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N18 compound treatment 0.277 0.0288 1.55 1.5463 1.0 1206859 TimTec1_002768 Brc1cncc(c1)C(=O)Nc2ccc(cc2)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N19 compound treatment 0.246 -0.00223 -0.12 -0.1196 -1.0 1560261 TimTec1_002769 COc1ccc(cc1)C2NCCc3cc(OC)c(OC)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N20 compound treatment 0.279 0.0308 1.65 1.6537 1.0 3209245 TimTec1_002770 CN(C)c1nc(NCc2ccccc2)nc(Nc3ccc(OC(F)(F)F)cc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N21 compound treatment 0.263 0.0148 0.79 0.7939 1.0 1425208 TimTec1_002771 CN(CC(=O)O)S(=O)(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N22 compound treatment 0.343 0.0948 5.09 5.093 1.0 3209246 TimTec1_002772 Nn1c(CSCc2ccccc2)nnc1CSCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N23 mock treatment 0.248 -2.26E-4 -0.01 -0.0121 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 N24 mock treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O01 compound treatment 0.44 0.192 10.31 10.3055 1.0 3083272 TimTec1_002773 C(Nc1nonc1c2ncon2)n3nnc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O02 compound treatment 0.264 0.0158 0.85 0.8477 1.0 3209247 TimTec1_002774 O=C(NC1CCCCC1)/C=C/c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O03 compound treatment 0.267 0.0188 1.01 1.0089 1.0 3209248 TimTec1_002775 O=C(NCCc1ccccc1)c2c(/N=C/3\C(=O)Nc4ccccc34)sc5CCCCc25 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O04 compound treatment 0.278 0.0298 1.6 1.6 1.0 1468374 TimTec1_002776 OC(c1cccs1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O05 compound treatment 0.281 0.0328 1.76 1.7612 1.0 3209249 TimTec1_002777 Clc1ccc(Cl)c(c1)N2C(SCC2=O)/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O06 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 1257164 TimTec1_002778 Cc1ccc(C)c(NCc2ccccc2CO)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O07 compound treatment 0.48 0.232 12.46 12.4551 1.0 3083858 TimTec1_002779 Cc1nc2ccccc2nc1Sc3nnc(o3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O08 compound treatment 0.272 0.0238 1.28 1.2776 1.0 1918856 TimTec1_002780 Brc1ccc(/C=N/c2cccc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O09 compound treatment 0.265 0.0168 0.9 0.9014 1.0 3209250 TimTec1_002781 COc1ccc(Br)cc1/C=C/2\C(=O)NC(=O)N(CCC3=CCCCC3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O10 compound treatment 0.256 0.00777 0.42 0.4178 1.0 3209251 TimTec1_002782 N#Cc1ccc(/C=N/c2cccc(C#N)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O11 compound treatment 0.365 0.117 6.28 6.2752 1.0 3083924 TimTec1_002783 CCN1C(=C)c2cc(C)cc(C)c2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O12 compound treatment 0.378 0.13 6.97 6.9738 1.0 3209252 TimTec1_002784 COc1ccc2ccccc2c1/C=N/c3ccccc3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O13 compound treatment 0.277 0.0288 1.55 1.5463 1.0 1178846 TimTec1_002785 C=CCSc1nc2ccccc2c(=O)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O14 compound treatment 0.291 0.0428 2.3 2.2986 1.0 3209253 TimTec1_002786 Cc1ccc(/C=N/c2ccc(\N=C\c3ccc(C)s3)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O15 compound treatment 0.463 0.215 11.54 11.5415 1.0 1364793 TimTec1_002787 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2sc(C)c(C)c2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O16 compound treatment 0.325 0.0768 4.13 4.1257 1.0 3209254 TimTec1_002788 Cc1c(Cc2ccccc2)sc(/N=C/c3ccc(Cl)cc3)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O17 compound treatment 0.459 0.211 11.33 11.3266 1.0 1685792 TimTec1_002789 COc1ccc2c(Cl)c(sc2c1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O18 compound treatment 0.329 0.0808 4.34 4.3406 1.0 1138448 TimTec1_002790 O=C(CSc1nc2CCCCc2cc1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O19 compound treatment 0.255 0.00677 0.36 0.364 1.0 3083928 TimTec1_002791 CSc1ccc(/C=N/c2ccc(C)c(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O20 compound treatment 0.453 0.205 11.0 11.0041 1.0 1253093 TimTec1_002792 CCOc1cccc(=O)c2c(C)n(c(C)c12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O21 compound treatment 0.277 0.0288 1.55 1.5463 1.0 3083930 TimTec1_002793 Cc1ccc(/C=N/c2ccc3ccccc3c2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O22 compound treatment 0.277 0.0288 1.55 1.5463 1.0 3209255 TimTec1_002794 C/C(=N/Cc1nnc(C)s1)/c2cc3c(=O)n(C)c4ccccc4c3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O23 mock treatment 0.246 -0.00223 -0.12 -0.1196 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 O24 mock treatment 0.243 -0.00523 -0.28 -0.2808 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P01 compound treatment 0.24 -0.00823 -0.44 -0.442 -1.0 3083932 TimTec1_002795 CC1=CC(=O)N(C1=O)c2c(C)n(C)n(c3ccccc3)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P02 compound treatment 0.239 -0.00923 -0.5 -0.4958 -1.0 3209256 TimTec1_002796 CNC(=O)C1=CC(C)(C)NC1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P03 compound treatment 0.238 -0.0102 -0.55 -0.5495 -1.0 1174268 TimTec1_002797 Clc1ccc(cc1)C(=O)C(=C2NCCN2)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P04 compound treatment 0.245 -0.00323 -0.17 -0.1733 -1.0 1414675 TimTec1_002798 O=C(N1CCOCC1)c2ccc(s2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P05 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 1495833 TimTec1_002799 COc1ccc(cc1OC)C2=NCC(C)(C)CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P06 compound treatment 0.551 0.303 16.27 16.2705 1.0 1678629 TimTec1_002800 COc1ccccc1C(=O)Nc2ccc(cc2)c3cn4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P07 compound treatment 0.312 0.0638 3.43 3.4271 1.0 3209373 TimTec1_002801 CCn1c(=O)c(C/2=NNC(=O)\C2=C/Nc3nccs3)c(O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P08 compound treatment 0.376 0.128 6.87 6.8663 1.0 1514165 TimTec1_002802 COc1ccc(cc1)C(C#N)N2CCC(=N2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P09 compound treatment 0.295 0.0468 2.51 2.5135 1.0 1619442 TimTec1_002803 Nc1cccc(c1)C(=O)OC2CSC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P10 compound treatment 0.492 0.244 13.1 13.0999 1.0 3209374 TimTec1_002804 Cc1ccc(OCCSc2ncnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P11 compound treatment 0.263 0.0148 0.79 0.7939 1.0 1011278 TimTec1_002805 OC(=O)CNC(=O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P12 compound treatment 0.287 0.0388 2.08 2.0836 1.0 1159913 TimTec1_002806 NC(=O)Cc1nc(cs1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P13 compound treatment 0.36 0.112 6.01 6.0065 1.0 1445633 TimTec1_002807 CCC(=O)c1cc2OCCOc2cc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P14 compound treatment 0.236 -0.0122 -0.66 -0.657 -1.0 1468490 TimTec1_002808 Clc1ccccc1CS(=O)(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P15 compound treatment 0.284 0.0358 1.92 1.9224 1.0 1633493 TimTec1_002809 NC(=O)CSc1nc2ccccc2c(=O)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P16 compound treatment 0.239 -0.00923 -0.5 -0.4958 -1.0 1674139 TimTec1_002810 CCOC(=O)C1CCN(CC1)C(=O)c2ccccc2NC(=O)c3cccc(F)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P17 compound treatment 0.267 0.0188 1.01 1.0089 1.0 1703140 TimTec1_002811 OC(=O)CC1(O)N(Cc2ccccc2)C(=O)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P18 compound treatment 0.236 -0.0122 -0.66 -0.657 -1.0 3084009 TimTec1_002812 COC(=O)C1=CN(CC2CCCO2)C=C(C1c3ccccc3)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P19 compound treatment 0.261 0.0128 0.69 0.6865 1.0 1281947 TimTec1_002813 CC1(C)CC(=C(C(C(C#N)C(=S)N)c2ccc(Cl)cc2)C(=O)C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P20 compound treatment 0.339 0.0908 4.88 4.878 1.0 3084012 TimTec1_002814 O=C(C1CCCC1)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P21 compound treatment 0.258 0.00977 0.53 0.5252 1.0 1667550 TimTec1_002815 Clc1ccccc1C(=O)N2CC(CC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P22 compound treatment 0.242 -0.00623 -0.33 -0.3346 -1.0 3209375 TimTec1_002816 CC(=O)NC(N1CCCCC1c2cccnc2)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P23 mock treatment 0.228 -0.0202 -1.09 -1.0869 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2070 P24 mock treatment 0.24 -0.00823 -0.44 -0.442 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A01 compound treatment 0.269 0.0172 0.92 0.9219 1.0 3084014 TimTec1_002817 COCCc1nnc(CCOC)n1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A02 compound treatment 0.216 -0.0358 -1.93 -1.9262 -1.0 3084016 TimTec1_002818 COC(=O)Cc1[nH]nc2OC(=C(C#N)C3(CCOC3C)c12)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A03 compound treatment 0.223 -0.0288 -1.55 -1.55 -1.0 1505030 TimTec1_002819 CC(=O)NC1CC(C)(C)N(OC(=O)c2ccccn2)C(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A04 compound treatment 0.305 0.0532 2.86 2.8565 1.0 1622909 TimTec1_002820 COc1cccc(NC(=O)CCC(=O)Nc2cccc(OC)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A05 compound treatment 0.273 0.0212 1.14 1.1369 1.0 1232935 TimTec1_002821 COC(=O)c1ccc2OCC(=O)Nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A06 compound treatment 0.293 0.0412 2.21 2.2117 1.0 1338496 TimTec1_002822 O=C(Cc1ccccc1)Nc2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A07 compound treatment 0.227 -0.0248 -1.34 -1.3351 -1.0 1686991 TimTec1_002823 O=C(NC1(CC1)c2ccccc2)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A08 compound treatment 0.311 0.0592 3.18 3.1789 1.0 1704723 TimTec1_002824 COc1ccccc1OCC(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A09 compound treatment 0.335 0.0832 4.47 4.4686 1.0 1538860 TimTec1_002825 COc1nc(C#N)nc(n1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A10 compound treatment 0.274 0.0222 1.19 1.1906 1.0 1705636 TimTec1_002826 COC(=O)CCC(=O)c1c(C)[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A11 compound treatment 0.243 -0.00884 -0.48 -0.4752 -1.0 1667965 TimTec1_002827 O=C(N1CC(=O)N(CCc2ccccc2)C(=O)C1)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A12 compound treatment 0.27 0.0182 0.98 0.9757 1.0 1335542 TimTec1_002828 NS(=O)(=O)c1ccc(NC(=O)C2CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A13 compound treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 1346198 TimTec1_002829 CC(=O)Nc1ccc(NC(=O)NC2(CC2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A14 compound treatment 0.394 0.142 7.64 7.6392 1.0 1605519 TimTec1_002830 COc1ccc(cc1)C(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A15 compound treatment 0.258 0.00616 0.33 0.3308 1.0 1396894 TimTec1_002831 CC(=O)ON1C(C)(C)CC(CC1(C)C)OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A16 compound treatment 0.5 0.248 13.34 13.3354 1.0 1437131 TimTec1_002832 COc1ccc(NC(=S)NC(=O)COc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A17 compound treatment 0.256 0.00416 0.22 0.2233 1.0 3209376 TimTec1_002833 CC(CN(C)C)Sc1nc(C)cc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A18 compound treatment 0.296 0.0442 2.37 2.3729 1.0 3084025 TimTec1_002834 C/C(=N/O)/C1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A19 compound treatment 0.302 0.0502 2.7 2.6953 1.0 1530326 TimTec1_002835 O=C(Cn1nc2-c3ccccc3C(=O)c4cccc1c24)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A20 compound treatment 0.418 0.166 8.93 8.9289 1.0 1340976 TimTec1_002836 Cc1ccccc1NCC(=O)NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A21 compound treatment 0.508 0.256 13.77 13.7653 1.0 1679889 TimTec1_002837 CC(=O)Nc1ccc2c(C)cc(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A22 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1127034 TimTec1_002838 OC(=O)CCC(=O)NC1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A23 mock treatment 0.254 0.00216 0.12 0.1159 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 A24 mock treatment 0.275 0.0232 1.24 1.2444 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B01 compound treatment 0.252 1.56E-4 0.01 0.0084 1.0 1361487 TimTec1_002839 CCC(=O)Nc1ccccc1c2ccccc2NC(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B02 compound treatment 0.3 0.0482 2.59 2.5878 1.0 3209377 TimTec1_002840 COc1ccc(CC(=O)N(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B03 compound treatment 0.271 0.0192 1.03 1.0294 1.0 3209378 TimTec1_002841 O=C(NCCCc1ccccc1)C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B04 compound treatment 0.268 0.0162 0.87 0.8682 1.0 1049258 TimTec1_002842 O=C(N1CCN(CC1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B05 compound treatment 0.26 0.00816 0.44 0.4383 1.0 3084098 TimTec1_002843 O=C(CCCc1ccccc1)Nc2scc3c(=O)oc4ccccc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B06 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1415764 TimTec1_002844 CCC(C)NC(=O)Cc1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B07 compound treatment 0.263 0.0112 0.6 0.5995 1.0 3209379 TimTec1_002845 Ic1cccc(c1)C(=O)Nc2ccccc2C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B08 compound treatment 0.238 -0.0138 -0.74 -0.7439 -1.0 1699287 TimTec1_002846 CCOC(=O)N1CCN(CC1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B09 compound treatment 0.479 0.227 12.21 12.2069 1.0 3209380 TimTec1_002847 Cc1ccc(cc1)n2c(SCc3cccc(c3)C(F)(F)F)nnc2c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B10 compound treatment 0.339 0.0872 4.68 4.6836 1.0 1149703 TimTec1_002848 COc1ccc(cc1)S(=O)(=O)N(CCO)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B11 compound treatment 0.346 0.0942 5.06 5.0598 1.0 3209381 TimTec1_002849 FC(F)(F)c1ccc(/C=N\n2c(S)nnc2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B12 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1570349 TimTec1_002850 CS(=O)(=O)NC1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B13 compound treatment 0.259 0.00716 0.38 0.3846 1.0 1666129 TimTec1_002851 CN(C)CCc1[nH]c2ccc(C)cc2c1CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B14 compound treatment 0.234 -0.0178 -0.96 -0.9589 -1.0 3084104 TimTec1_002852 CC(C)(C)NS(=O)(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B15 compound treatment 0.369 0.117 6.3 6.2957 1.0 1361349 TimTec1_002853 CC(=O)N1CC2N(CCc3ccccc23)C1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B16 compound treatment 0.257 0.00516 0.28 0.2771 1.0 1603417 TimTec1_002854 NC(=O)c1cccc(c1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B17 compound treatment 0.281 0.0292 1.57 1.5668 1.0 1380307 TimTec1_002855 Nc1ncnc2[nH]c(Sc3ncnc4ccccc34)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B18 compound treatment 0.276 0.0242 1.3 1.2981 1.0 1630576 TimTec1_002856 Clc1cccc(c1)C(=O)NCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B19 compound treatment 0.411 0.159 8.55 8.5527 1.0 3209382 TimTec1_002857 Cc1ccc(cc1)S(=O)(=O)N2CCN(CC2)c3nc(NC4CCCC4)c5ccccc5n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B20 compound treatment 0.256 0.00416 0.22 0.2233 1.0 1014173 TimTec1_002858 CC(C)C(=O)Nc1cccc(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B21 compound treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 1540718 TimTec1_002859 Cn1c2nc(c(C(=S)Nc3ccccc3)n2c4ccccc14)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B22 compound treatment 0.289 0.0372 2.0 1.9967 1.0 3084109 TimTec1_002860 C=CCN(CC=C)S(=O)(=O)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B23 mock treatment 0.246 -0.00584 -0.31 -0.314 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 B24 mock treatment 0.238 -0.0138 -0.74 -0.7439 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C01 compound treatment 0.394 0.142 7.64 7.6392 1.0 3084110 TimTec1_002861 Nn1c(nnc1c2ccccn2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C02 compound treatment 0.328 0.0762 4.09 4.0925 1.0 3209504 TimTec1_002862 Cc1ccc(o1)c2cc(c3c(N)c(sc3n2)C(=O)c4ccc5OCOc5c4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C03 compound treatment 0.238 -0.0138 -0.74 -0.7439 -1.0 1686195 TimTec1_002863 COc1ccc(CNC2CC(C)(C)NC(C)(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C04 compound treatment 0.246 -0.00584 -0.31 -0.314 -1.0 1012738 TimTec1_002864 COC(=O)CCC(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C05 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 3084183 TimTec1_002865 O=C(NCCCN1CCOCC1)NC2(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C06 compound treatment 0.334 0.0822 4.41 4.4149 1.0 1524311 TimTec1_002866 Cc1ccccc1OCC(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C07 compound treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 1120456 TimTec1_002867 COc1ccc(NC(=O)OCC23COCN3COC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C08 compound treatment 0.296 0.0442 2.37 2.3729 1.0 1872857 TimTec1_002868 Nc1ccc(/C=C/c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C09 compound treatment 0.255 0.00316 0.17 0.1696 1.0 1455445 TimTec1_002869 CCOc1cc2CCN3C(c2cc1OCC)c4ccccc4OCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C10 compound treatment 0.267 0.0152 0.81 0.8145 1.0 1520503 TimTec1_002870 S=C(NCc1ccccc1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C11 compound treatment 0.253 0.00116 0.06 0.0621 1.0 3084189 TimTec1_002871 Cc1sc([s+]c1SCC(=O)O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C12 compound treatment 0.255 0.00316 0.17 0.1696 1.0 3084190 TimTec1_002872 O=C(NCc1ccccc1)C2CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C13 compound treatment 0.269 0.0172 0.92 0.9219 1.0 1274042 TimTec1_002873 COCc1cc(C)nc2sc3c(=O)n(Cc4ccccc4)nnc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C14 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 1250141 TimTec1_002874 Nc1ccc(cc1)S(=O)(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C15 compound treatment 0.271 0.0192 1.03 1.0294 1.0 1229823 TimTec1_002875 COc1ccc(cc1)S(=O)(=O)NCC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C16 compound treatment 0.257 0.00516 0.28 0.2771 1.0 1379532 TimTec1_002876 O=C(Cc1ccccc1)NC2CCCCC2NC(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C17 compound treatment 0.329 0.0772 4.15 4.1462 1.0 1324864 TimTec1_002877 CC1CCN(CNC(=O)c2cc3ccccc3o2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C18 compound treatment 0.46 0.208 11.19 11.1859 1.0 1456811 TimTec1_002878 CC(=O)Nc1sc(Cc2ccccc2)c(C)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C19 compound treatment 0.254 0.00216 0.12 0.1159 1.0 1430592 TimTec1_002879 COc1ccc(c2ccccc12)S(=O)(=O)N(C)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C20 compound treatment 0.427 0.175 9.41 9.4125 1.0 1271718 TimTec1_002880 COc1ccc(OC)c(NC(=O)COc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C21 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1255886 TimTec1_002881 CCC(CO)NC(=S)Nc1ccccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C22 compound treatment 0.364 0.112 6.03 6.027 1.0 3209505 TimTec1_002882 CC1=NN(C(=S)N)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C23 mock treatment 0.265 0.0132 0.71 0.707 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 C24 mock treatment 0.267 0.0152 0.81 0.8145 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D01 compound treatment 0.319 0.0672 3.61 3.6088 1.0 1352115 TimTec1_002883 Fc1ccc(NC(=O)CCCC(=O)Nc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D02 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 3084196 TimTec1_002884 CC1CCCCN1C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D03 compound treatment 0.505 0.253 13.6 13.6041 1.0 1725355 TimTec1_002885 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCCC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D04 compound treatment 0.389 0.137 7.37 7.3705 1.0 1463458 TimTec1_002886 CCOc1ccccc1NC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D05 compound treatment 0.48 0.228 12.26 12.2606 1.0 3209506 TimTec1_002887 O=C(CSc1nc(c(C#N)c(=O)[nH]1)c2ccccc2)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D06 compound treatment 0.263 0.0112 0.6 0.5995 1.0 1121637 TimTec1_002888 CCOc1ccc(NC(=O)c2c(OC)cccc2OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D07 compound treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 3084200 TimTec1_002889 O=C(Nc1ccccc1C(=O)N2CCCC2)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D08 compound treatment 0.26 0.00816 0.44 0.4383 1.0 3209507 TimTec1_002890 C=CCN(CC=C)C(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D09 compound treatment 0.37 0.118 6.35 6.3495 1.0 3084201 TimTec1_002891 Oc1ccc(Br)cc1/C=N/n2cnnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D10 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1391704 TimTec1_002892 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D11 compound treatment 0.463 0.211 11.35 11.3471 1.0 3084275 TimTec1_002893 CC(C)(C)c1ccc(cc1)c2nnc(S)n2/N=C/c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D12 compound treatment 0.254 0.00216 0.12 0.1159 1.0 1455818 TimTec1_002894 CS(=O)(=O)N1CCN(CC1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D13 compound treatment 0.407 0.155 8.34 8.3378 1.0 1401683 TimTec1_002895 Cc1ccc(cc1)S(=O)(=O)c2c[nH]c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D14 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 3209508 TimTec1_002896 CCN(CC)S(=O)(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D15 compound treatment 0.266 0.0142 0.76 0.7607 1.0 1643931 TimTec1_002897 C(Nc1nc(Nc2nc(cs2)c3ccccc3)nc(n1)N4CCCCC4)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D16 compound treatment 0.28 0.0282 1.51 1.5131 1.0 3084279 TimTec1_002898 CN(Cc1ccccc1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D17 compound treatment 0.467 0.215 11.56 11.562 1.0 1184589 TimTec1_002899 CCN1C(Nc2ccccc12)SCC(=O)Nc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D18 compound treatment 0.271 0.0192 1.03 1.0294 1.0 3084281 TimTec1_002900 CC(C)NC(=O)c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D19 compound treatment 0.507 0.255 13.71 13.7116 1.0 3084282 TimTec1_002901 Clc1ccc(OCCSc2ncnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D20 compound treatment 0.255 0.00316 0.17 0.1696 1.0 1014159 TimTec1_002902 CC(C)C(=O)Nc1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D21 compound treatment 0.302 0.0502 2.7 2.6953 1.0 3209509 TimTec1_002903 OC(=O)CSc1nnc(COc2ccc(Cl)cc2)n1c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D22 compound treatment 0.282 0.0302 1.62 1.6205 1.0 1280619 TimTec1_002904 CC1CC(C)CN(C1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D23 mock treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 D24 mock treatment 0.242 -0.00984 -0.53 -0.529 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E01 compound treatment 0.241 -0.0108 -0.58 -0.5827 -1.0 1488202 TimTec1_002905 COc1ccc(CCNC2=CC(=O)OC32CCCCC3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E02 compound treatment 0.287 0.0352 1.89 1.8892 1.0 3084286 TimTec1_002906 Cc1csc(NC(=O)c2sc3nc4CCCc4c(c3c2N)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E03 compound treatment 0.252 1.56E-4 0.01 0.0084 1.0 1319939 TimTec1_002907 CCc1ccc(cc1)C2NCCc3cc4OCCOc4cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E04 compound treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 1079846 TimTec1_002908 OC(=O)c1ccccc1C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E05 compound treatment 0.235 -0.0168 -0.91 -0.9051 -1.0 1117234 TimTec1_002909 OCCNC1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E06 compound treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 3084289 TimTec1_002910 O=C(NCc1ccccc1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E07 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 3209510 TimTec1_002911 COC(=O)C1=CN(CC2(CC3CC4CC(C3)C2)C4)C=C(C1c5cccs5)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E08 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 1872860 TimTec1_002912 CN(CCc1ccc(C)[n+]([O-])c1)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E09 compound treatment 0.241 -0.0108 -0.58 -0.5827 -1.0 1384251 TimTec1_002913 C1CN(CCO1)c2ncnc(n2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E10 compound treatment 0.254 0.00216 0.12 0.1159 1.0 1653066 TimTec1_002914 Cc1ccc(OCC(=O)Oc2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E11 compound treatment 0.238 -0.0138 -0.74 -0.7439 -1.0 3209511 TimTec1_002915 Cc1sc([s+]c1SCCC(=O)O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E12 compound treatment 0.289 0.0372 2.0 1.9967 1.0 1739781 TimTec1_002916 Clc1ccc(OCC(=O)Oc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E13 compound treatment 0.532 0.28 15.06 15.055 1.0 1256719 TimTec1_002917 Clc1ccccc1CC2OC(=O)c3c2cc[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E14 compound treatment 0.264 0.0122 0.65 0.6533 1.0 1005147 TimTec1_002918 COc1ccc(OCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E15 compound treatment 0.44 0.188 10.11 10.1111 1.0 3083277 TimTec1_002919 O=C(NCCOC1(CC2CC3CC(C2)C1)C3)c4cc5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E16 compound treatment 0.433 0.181 9.73 9.735 1.0 3083279 TimTec1_002920 Cc1ccc(cc1)C(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E17 compound treatment 0.374 0.122 6.56 6.5644 1.0 3209512 TimTec1_002921 O=C(COc1cccc(NC(=O)c2ccccc2)c1)NCCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E18 compound treatment 0.274 0.0222 1.19 1.1906 1.0 1330948 TimTec1_002922 OC(=O)CCC(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E19 compound treatment 0.261 0.00916 0.49 0.492 1.0 1780563 TimTec1_002923 OC(=O)CNC(=O)c1cc(=O)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E20 compound treatment 0.284 0.0322 1.73 1.728 1.0 1661667 TimTec1_002924 COc1ccc(CC(=O)Nc2ccc(OC)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E21 compound treatment 0.325 0.0732 3.93 3.9313 1.0 3083283 TimTec1_002925 COc1nsc(NN)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E22 compound treatment 0.28 0.0282 1.51 1.5131 1.0 3083284 TimTec1_002926 Cc1cc(C)n(n1)C(=O)CNc2cccc(Cl)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E23 mock treatment 0.254 0.00216 0.12 0.1159 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 E24 mock treatment 0.261 0.00916 0.49 0.492 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F01 compound treatment 0.262 0.0102 0.55 0.5458 1.0 1189735 TimTec1_002927 CCOc1ccc(NC(=O)CCC(=O)n2nc(C)cc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F02 compound treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 1346484 TimTec1_002928 OCCN1CCN(CC1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F03 compound treatment 0.401 0.149 8.02 8.0153 1.0 1244795 TimTec1_002929 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCC2)c3ccc(COc4ccc5CCCc5c4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F04 compound treatment 0.294 0.0422 2.27 2.2654 1.0 3083288 TimTec1_002930 Brc1ccc(cc1)C(=O)NCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F05 compound treatment 0.243 -0.00884 -0.48 -0.4752 -1.0 1551713 TimTec1_002931 CC1=NN(C(=O)C1)c2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F06 compound treatment 0.24 -0.0118 -0.64 -0.6365 -1.0 1278318 TimTec1_002932 Cc1cccc(NC(=O)c2cccnc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F07 compound treatment 0.248 -0.00384 -0.21 -0.2066 -1.0 3209639 TimTec1_002933 COc1ccc(NC(=O)n2ccc(n2)C(=O)N3CCOCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F08 compound treatment 0.259 0.00716 0.38 0.3846 1.0 3083290 TimTec1_002934 CC1CC(C)CN(C1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F09 compound treatment 0.302 0.0502 2.7 2.6953 1.0 3209640 TimTec1_002935 C/C(=C\c1ccco1)/C=N/N2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F10 compound treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 3083291 TimTec1_002936 CC(C)CNS(=O)(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F11 compound treatment 0.501 0.249 13.39 13.3891 1.0 3209641 TimTec1_002937 Sc1nnc(c2cccnc2)n1/N=C/C=C/c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F12 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 3083293 TimTec1_002938 CC(C)NC(=O)c1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F13 compound treatment 0.27 0.0182 0.98 0.9757 1.0 1394669 TimTec1_002939 OC(=O)COc1ccc(NS(=O)(=O)c2cccc3nsnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F14 compound treatment 0.236 -0.0158 -0.85 -0.8514 -1.0 1007338 TimTec1_002940 CS(=O)(=O)NC(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F15 compound treatment 0.387 0.135 7.26 7.263 1.0 1623851 TimTec1_002941 CN1CCC2C(C1)c3cc(C)ccc3N2C(=O)Cn4nnc(n4)c5ccccc5C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F16 compound treatment 0.278 0.0262 1.41 1.4056 1.0 3083330 TimTec1_002942 CCC1CCCCN1S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F17 compound treatment 0.487 0.235 12.64 12.6368 1.0 3209642 TimTec1_002943 O=C(Cn1cc(/C=C\2/C(=O)NC(=O)N(Cc3ccco3)C2=O)c4ccccc14)NCC5CCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F18 compound treatment 0.324 0.0722 3.88 3.8775 1.0 1208206 TimTec1_002944 Fc1ccc(cc1)C(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F19 compound treatment 0.291 0.0392 2.1 2.1042 1.0 3083297 TimTec1_002945 COc1ccc(cc1)/C(=C/C2=NC(C)(C)CO2)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F20 compound treatment 0.302 0.0502 2.7 2.6953 1.0 3209643 TimTec1_002946 COC(=O)c1ccc(NC(=O)C(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F21 compound treatment 0.303 0.0512 2.75 2.749 1.0 1165003 TimTec1_002947 CC1=C(C)CC(C(C1)C(=O)O)C(=O)Nc2ccc3c(c2)oc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F22 compound treatment 0.23 -0.0218 -1.17 -1.1738 -1.0 1151238 TimTec1_002948 O=S(=O)(Cc1ccccc1)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F23 mock treatment 0.267 0.0152 0.81 0.8145 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 F24 mock treatment 0.228 -0.0238 -1.28 -1.2813 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G01 compound treatment 0.287 0.0352 1.89 1.8892 1.0 1275078 TimTec1_002949 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2nc3nc(C)cc(C)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G02 compound treatment 0.278 0.0262 1.41 1.4056 1.0 3209644 TimTec1_002950 CCCCc1[nH]nc2OC(=C(C#N)C3(CCCCC3)c12)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G03 compound treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 1154081 TimTec1_002951 COC(=O)Nc1c(Cl)nsc1S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G04 compound treatment 0.252 1.56E-4 0.01 0.0084 1.0 1466731 TimTec1_002952 Cc1ccc(OC(=O)CCC(=O)Nc2cccc(C#N)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G05 compound treatment 0.242 -0.00984 -0.53 -0.529 -1.0 1082369 TimTec1_002953 NCCNC1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G06 compound treatment 0.51 0.258 13.87 13.8728 1.0 3209645 TimTec1_002954 NC(=O)c1ccccc1NC(=O)CCCOc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G07 compound treatment 0.293 0.0412 2.21 2.2117 1.0 1419997 TimTec1_002955 Fc1ccc(OCC(=O)n2cnc3ccccc23)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G08 compound treatment 0.238 -0.0138 -0.74 -0.7439 -1.0 1305850 TimTec1_002956 CC(NC(=O)c1ccncc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G09 compound treatment 0.333 0.0812 4.36 4.3612 1.0 1253485 TimTec1_002957 O=C(Nc1ccccc1)c2scc3CCCCc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G10 compound treatment 0.235 -0.0168 -0.91 -0.9051 -1.0 1154113 TimTec1_002958 COC(=O)C1CNCCN1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G11 compound treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 1479855 TimTec1_002959 Nc1cc(O)nc(SCC(=O)NC2CCCCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G12 compound treatment 0.262 0.0102 0.55 0.5458 1.0 3083867 TimTec1_002960 CC1CCN(CC1)S(=O)(=O)c2ccc(/N=C/3\C(=O)Nc4ccccc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G13 compound treatment 0.285 0.0332 1.78 1.7817 1.0 1231567 TimTec1_002961 O=C1Nc2ccccc2C1C3Sc4ccccc4NC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G14 compound treatment 0.292 0.0402 2.16 2.1579 1.0 3083940 TimTec1_002962 O=c1ccn([nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G15 compound treatment 0.293 0.0412 2.21 2.2117 1.0 3083942 TimTec1_002963 COC(=O)c1ccc2CCc3cccc1c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G16 compound treatment 0.438 0.186 10.0 10.0036 1.0 3083945 TimTec1_002964 Clc1ccc(cc1)C(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G17 compound treatment 0.307 0.0552 2.96 2.964 1.0 3083946 TimTec1_002965 Cc1ccc(cc1)S(=O)(=O)NCCSc2nnnn2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G18 compound treatment 0.253 0.00116 0.06 0.0621 1.0 3209646 TimTec1_002966 CC1=NN(C(=S)N)C(=O)C1C(C(C#N)C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G19 compound treatment 0.296 0.0442 2.37 2.3729 1.0 1312727 TimTec1_002967 COc1ccccc1C(CC(=O)N2CCCC2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G20 compound treatment 0.248 -0.00384 -0.21 -0.2066 -1.0 1605427 TimTec1_002968 Cc1ccccc1NC(=O)CCC(=O)Nc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G21 compound treatment 0.383 0.131 7.05 7.0481 1.0 3209647 TimTec1_002969 CCC1CCc2nc3sc(C(=O)NCCc4ccc(OC)cc4)c(N)c3cc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G22 compound treatment 0.329 0.0772 4.15 4.1462 1.0 1624978 TimTec1_002970 O=C(Nc1ccccc1)Nc2ccc(Nc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G23 mock treatment 0.272 0.0202 1.08 1.0832 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 G24 mock treatment 0.247 -0.00484 -0.26 -0.2603 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H01 compound treatment 0.56 0.308 16.56 16.5597 1.0 1612290 TimTec1_002971 O=C(CCCC(=O)N1CCCc2ccccc12)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H02 compound treatment 0.261 0.00916 0.49 0.492 1.0 1583605 TimTec1_002972 CC1CCCCN1S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H03 compound treatment 0.408 0.156 8.39 8.3915 1.0 3209648 TimTec1_002973 NC(=O)c1ccccc1NC(=O)c2cccc(COc3ccc4CCCc4c3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H04 compound treatment 0.277 0.0252 1.35 1.3518 1.0 1192634 TimTec1_002974 CCOc1ccccc1NC(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H05 compound treatment 0.258 0.00616 0.33 0.3308 1.0 1045732 TimTec1_002975 O=P(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H06 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1524458 TimTec1_002976 CCN(Cc1ccccc1)C(=O)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H07 compound treatment 0.401 0.149 8.02 8.0153 1.0 3209649 TimTec1_002977 Clc1ccc(NC(=O)c2cc[nH]n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H08 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 1548424 TimTec1_002978 OCCN(Cc1ccccc1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H09 compound treatment 0.29 0.0382 2.05 2.0504 1.0 3209650 TimTec1_002979 C(N1CCN(CC1)/N=C/c2ccco2)c3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H10 compound treatment 0.282 0.0302 1.62 1.6205 1.0 3083954 TimTec1_002980 Clc1ccc(Cl)c(c1)S(=O)(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H11 compound treatment 0.257 0.00516 0.28 0.2771 1.0 3209651 TimTec1_002981 Sc1nnc(C2CCCCC2)n1/N=C\c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H12 compound treatment 0.258 0.00616 0.33 0.3308 1.0 3209652 TimTec1_002982 CCCN(CCC)C(=O)c1ccccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H13 compound treatment 0.287 0.0352 1.89 1.8892 1.0 3083957 TimTec1_002983 Fc1ccc(cc1)c2csc(n2)N3CCN(C/C=C\c4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H14 compound treatment 0.273 0.0212 1.14 1.1369 1.0 1721421 TimTec1_002984 CCC1CCCCN1C(=O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H15 compound treatment 0.299 0.0472 2.53 2.5341 1.0 1628659 TimTec1_002985 CC(=O)N(CCc1c(C)[nH]c2ccccc12)C(C(=O)Nc3c(C)cccc3C)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H16 compound treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 1214933 TimTec1_002986 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H17 compound treatment 0.261 0.00916 0.49 0.492 1.0 3209772 TimTec1_002987 Cc1cc(ccc1Br)c2ccc(/C=C\3/C(=O)NC(=O)N(C4CCCCC4)C3=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H18 compound treatment 0.258 0.00616 0.33 0.3308 1.0 3084027 TimTec1_002988 CC(C)NC(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H19 compound treatment 0.37 0.118 6.35 6.3495 1.0 1265488 TimTec1_002989 Clc1ccc(CN(CC(=O)N2CCCC2)S(=O)(=O)c3ccccc3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H20 compound treatment 0.333 0.0812 4.36 4.3612 1.0 3084032 TimTec1_002990 CC(C)C(=O)Nc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H21 compound treatment 0.267 0.0152 0.81 0.8145 1.0 1077722 TimTec1_002991 Cc1ccc(cc1)S(=O)(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H22 compound treatment 0.258 0.00616 0.33 0.3308 1.0 1060751 TimTec1_002992 O=S(=O)(Cc1ccccc1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H23 mock treatment 0.254 0.00216 0.12 0.1159 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 H24 mock treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I01 compound treatment 0.239 -0.0128 -0.69 -0.6902 -1.0 1532792 TimTec1_002993 CC(C)CCN1NC(C)(C)NC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I02 compound treatment 0.266 0.0142 0.76 0.7607 1.0 3209773 TimTec1_002994 Clc1ccc(OCCCC(=O)Nc2nccs2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I03 compound treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 1336661 TimTec1_002995 CC1(C)CC(CC(C)(C)N1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I04 compound treatment 0.46 0.208 11.19 11.1859 1.0 1482766 TimTec1_002996 Cc1cccc(OCC(=O)Nc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I05 compound treatment 0.258 0.00616 0.33 0.3308 1.0 1626149 TimTec1_002997 Cc1[nH]c2ccccc2c1CCN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I06 compound treatment 0.296 0.0442 2.37 2.3729 1.0 3209774 TimTec1_002998 COC(=O)c1ccc(OC)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I07 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1162114 TimTec1_002999 COc1ccc(cc1)C(NC(=O)C2CC=CCC2C(=O)O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I08 compound treatment 0.259 0.00716 0.38 0.3846 1.0 1581961 TimTec1_003000 OC(=O)CCC(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I09 compound treatment 0.307 0.0552 2.96 2.964 1.0 3209775 TimTec1_003001 Cc1[nH]c2cc3c(cc(=O)[nH]c3cc2c1C)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I10 compound treatment 0.24 -0.0118 -0.64 -0.6365 -1.0 1329961 TimTec1_003002 OC(=O)C1C(C2CC1C=C2)C(=O)OCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I11 compound treatment 0.269 0.0172 0.92 0.9219 1.0 3209776 TimTec1_003003 Sc1nnnn1C2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I12 compound treatment 0.349 0.0972 5.22 5.221 1.0 1562475 TimTec1_003004 O=C(CCCC(=O)Nc1ccccc1C#N)Nc2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I13 compound treatment 0.259 0.00716 0.38 0.3846 1.0 3084037 TimTec1_003005 CCSc1nnc(C)c(O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I14 compound treatment 0.426 0.174 9.36 9.3588 1.0 1850983 TimTec1_003006 O=C(Cc1cccc2ccccc12)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I15 compound treatment 0.241 -0.0108 -0.58 -0.5827 -1.0 1481588 TimTec1_003007 O=C(NCN1CCCCC1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I16 compound treatment 0.316 0.0642 3.45 3.4476 1.0 3084039 TimTec1_003008 Clc1ccc(NC(=O)NCC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I17 compound treatment 0.259 0.00716 0.38 0.3846 1.0 3209777 TimTec1_003009 CCOC(=O)/C(=N/O)/C1=NC2(C)CCCCC2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I18 compound treatment 0.295 0.0432 2.32 2.3191 1.0 1346661 TimTec1_003010 NC(=O)CSc1nc2CCCCc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I19 compound treatment 0.424 0.172 9.25 9.2513 1.0 3209778 TimTec1_003011 CC1(C)Cc2c(cnn2c3ccc(F)cc3)-c4nc5ccccc5nc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I20 compound treatment 0.258 0.00616 0.33 0.3308 1.0 3209779 TimTec1_003012 O=C1C2CC=CCC2C(=O)N1c3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I21 compound treatment 0.278 0.0262 1.41 1.4056 1.0 3084043 TimTec1_003013 CSc1nc(cc(c1C#N)C(F)(F)F)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I22 compound treatment 0.396 0.144 7.75 7.7467 1.0 1352505 TimTec1_003014 NC(=O)c1c(NC(=O)Nc2ccccc2)sc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I23 mock treatment 0.261 0.00916 0.49 0.492 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 I24 mock treatment 0.265 0.0132 0.71 0.707 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J01 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1181166 TimTec1_003015 Cc1cc(C)cc(NC(=O)CCCC(=O)Nc2cc(C)cc(C)c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J02 compound treatment 0.367 0.115 6.19 6.1883 1.0 3209780 TimTec1_003016 COc1ccc(cc1)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J03 compound treatment 0.371 0.119 6.4 6.4032 1.0 3209781 TimTec1_003017 COC(=O)c1c(NC(=O)C2CC2c3ccccc3)scc1c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J04 compound treatment 0.27 0.0182 0.98 0.9757 1.0 3084046 TimTec1_003018 CC1CC(C)CN(C1)C(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J05 compound treatment 0.241 -0.0108 -0.58 -0.5827 -1.0 1016006 TimTec1_003019 C(Cc1ccccc1)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J06 compound treatment 0.242 -0.00984 -0.53 -0.529 -1.0 1618846 TimTec1_003020 O=C(N(CC#N)CC#N)c1cccc(c1)C(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J07 compound treatment 0.343 0.0912 4.9 4.8985 1.0 1010630 TimTec1_003021 NC(=N)Nc1nc2ccccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J08 compound treatment 0.269 0.0172 0.92 0.9219 1.0 3084116 TimTec1_003022 CC1CCCN(C1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J09 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 3209782 TimTec1_003023 C1CN(CCN1N=Cc2cccs2)C3c4ccccc4-c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J10 compound treatment 0.258 0.00616 0.33 0.3308 1.0 3084118 TimTec1_003024 Clc1ccc(Cl)c(c1)S(=O)(=O)NCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J11 compound treatment 0.353 0.101 5.44 5.4359 1.0 3209783 TimTec1_003025 Cn1cccc1/C=N/n2c(S)nnc2COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J12 compound treatment 0.248 -0.00384 -0.21 -0.2066 -1.0 1268911 TimTec1_003026 CCN(CC)C(=O)c1cccc(c1)C(=O)N(CC)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J13 compound treatment 0.321 0.0692 3.72 3.7163 1.0 1161626 TimTec1_003027 CN(C(=O)CSc1nc2ccccc2o1)C3(CCCCC3)C(=O)Nc4c(C)cccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J14 compound treatment 0.239 -0.0128 -0.69 -0.6902 -1.0 1594441 TimTec1_003028 O=C(Cc1ccccc1)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J15 compound treatment 0.309 0.0572 3.07 3.0715 1.0 1323967 TimTec1_003029 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc4OCN(Cc5ccccc5)Cc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J16 compound treatment 0.273 0.0212 1.14 1.1369 1.0 1294833 TimTec1_003030 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J17 compound treatment 0.259 0.00716 0.38 0.3846 1.0 3209784 TimTec1_003031 Cc1ccc(OCCCn2cc(/C=C\3/C(=O)NC(=O)N(C4CCCCC4)C3=O)c5ccccc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J18 compound treatment 0.246 -0.00584 -0.31 -0.314 -1.0 3084123 TimTec1_003032 CCC1CCCCN1C(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J19 compound treatment 0.26 0.00816 0.44 0.4383 1.0 3209785 TimTec1_003033 Cc1cccc(C)c1NCc2nnc(S)n2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J20 compound treatment 0.266 0.0142 0.76 0.7607 1.0 3084125 TimTec1_003034 CC(C)C(=O)N1CC(C)OC(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J21 compound treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 3209786 TimTec1_003035 O=C(NCCCN1CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J22 compound treatment 0.254 0.00216 0.12 0.1159 1.0 1472519 TimTec1_003036 O=S(=O)(Cc1ccccc1)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J23 mock treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 J24 mock treatment 0.242 -0.00984 -0.53 -0.529 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K01 compound treatment 0.42 0.168 9.04 9.0364 1.0 3209787 TimTec1_003037 Cc1[nH]c2ccc(OC(F)(F)F)cc2c1CCNC(=O)c3c(Cl)cnn3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K02 compound treatment 0.326 0.0742 3.99 3.985 1.0 1741001 TimTec1_003038 CC(=O)NS(=O)(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K03 compound treatment 0.268 0.0162 0.87 0.8682 1.0 1674832 TimTec1_003039 Cc1ccc2c3C(C4CCC=CC4)C5=C(CCCC5=O)Nc3ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K04 compound treatment 0.293 0.0412 2.21 2.2117 1.0 1039966 TimTec1_003040 Cc1cc(Br)ccc1OCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K05 compound treatment 0.281 0.0292 1.57 1.5668 1.0 3084130 TimTec1_003041 C=CCNC(=O)c1scc2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K06 compound treatment 0.361 0.109 5.87 5.8658 1.0 1150301 TimTec1_003042 COC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cc(C)cc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K07 compound treatment 0.264 0.0122 0.65 0.6533 1.0 3084131 TimTec1_003043 FC(F)(F)C(=C(C#N)C#N)NC1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K08 compound treatment 0.313 0.0612 3.29 3.2864 1.0 1711851 TimTec1_003044 OC(=O)CCCC(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K09 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1235296 TimTec1_003045 COC(=O)c1cc(=O)c2c(C)nc(nc2[nH]1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K10 compound treatment 0.248 -0.00384 -0.21 -0.2066 -1.0 1402776 TimTec1_003046 COc1ccc(cc1)N2C(=O)C3CC=CCC3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K11 compound treatment 0.402 0.15 8.07 8.0691 1.0 3084204 TimTec1_003047 COc1ccccc1C(=O)NCCOc2ccc(C)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K12 compound treatment 0.494 0.242 13.01 13.013 1.0 1478099 TimTec1_003048 O=C(CCCC(=O)Nc1cccc(C#N)c1)Nc2cccc(C#N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K13 compound treatment 0.35 0.0982 5.27 5.2747 1.0 1420277 TimTec1_003049 CCOc1nc(NCCC2=CCCCC2)nc(OCC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K14 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 3209907 TimTec1_003050 OC(=O)[C@H]1CCCC[C@H]1C(=O)N[C@H]2CCCC[C@@H]2NC(=O)[C@H]3CCCC[C@H]3C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K15 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1327396 TimTec1_003051 Oc1nc2ccccc2nc1C(=S)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K16 compound treatment 0.271 0.0192 1.03 1.0294 1.0 1197923 TimTec1_003052 Cc1cc(C)cc(NC(=O)c2ccccc2C(=O)O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K17 compound treatment 0.27 0.0182 0.98 0.9757 1.0 1529000 TimTec1_003053 CC1CCN(CC1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K18 compound treatment 0.287 0.0352 1.89 1.8892 1.0 1041191 TimTec1_003054 NCCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K19 compound treatment 0.261 0.00916 0.49 0.492 1.0 1201759 TimTec1_003055 Cc1nc2cccc(C(=O)O)c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K20 compound treatment 0.265 0.0132 0.71 0.707 1.0 1725455 TimTec1_003056 OC(=O)CSc1nc2CCCc2cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K21 compound treatment 0.32 0.0682 3.66 3.6626 1.0 3209908 TimTec1_003057 Cc1ccc(cc1)S(=O)(=O)CCSc2nc(cc(c2C#N)C(F)(F)F)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K22 compound treatment 0.265 0.0132 0.71 0.707 1.0 1144928 TimTec1_003058 OC(=O)c1ccccc1C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K23 mock treatment 0.248 -0.00384 -0.21 -0.2066 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 K24 mock treatment 0.256 0.00416 0.22 0.2233 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L01 compound treatment 0.53 0.278 14.95 14.9475 1.0 1440528 TimTec1_003059 CCN(CC)C(=O)COc1ccc2ccccc2c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L02 compound treatment 0.267 0.0152 0.81 0.8145 1.0 1517728 TimTec1_003060 CS(=O)(=O)N(Cc1ccccc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L03 compound treatment 0.465 0.213 11.45 11.4546 1.0 3209909 TimTec1_003061 Cc1nn(Cc2cccc3ccccc23)c(C)c1NC(=O)C4CC4c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L04 compound treatment 0.245 -0.00684 -0.37 -0.3678 -1.0 3084214 TimTec1_003062 CCCNC(=O)c1ccccc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L05 compound treatment 0.252 1.56E-4 0.01 0.0084 1.0 1514538 TimTec1_003063 O=C1OC(C2OC(=O)c3ccccc23)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L06 compound treatment 0.257 0.00516 0.28 0.2771 1.0 3084215 TimTec1_003064 FC(F)(F)c1ccccc1NC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L07 compound treatment 0.536 0.284 15.27 15.27 1.0 3209910 TimTec1_003065 CC(=C)CSc1nnc(SCc2cccc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L08 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1626374 TimTec1_003066 O=S(=O)(N(Cc1ccccc1)c2ccccn2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L09 compound treatment 0.284 0.0322 1.73 1.728 1.0 3084216 TimTec1_003067 Cn1cccc1C=NN2CCN(CC2)C3c4ccccc4-c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L10 compound treatment 0.289 0.0372 2.0 1.9967 1.0 3209911 TimTec1_003068 Clc1ccc(Cl)c(c1)S(=O)(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L11 compound treatment 0.494 0.242 13.01 13.013 1.0 1381409 TimTec1_003069 O=C(Nc1cccc(OC(=O)c2cccc(c2)S(=O)(=O)N3CCOCC3)c1)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L12 compound treatment 0.363 0.111 5.97 5.9733 1.0 3084218 TimTec1_003070 CCN(CC)S(=O)(=O)c1ccc(OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L13 compound treatment 0.329 0.0772 4.15 4.1462 1.0 1122440 TimTec1_003071 Clc1ccc(C(=O)n2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCCC4)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L14 compound treatment 0.257 0.00516 0.28 0.2771 1.0 3209912 TimTec1_003072 O=C(Cc1ccccc1)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L15 compound treatment 0.284 0.0322 1.73 1.728 1.0 3209913 TimTec1_003073 CC(C)c1ccc(cc1)S(=O)(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L16 compound treatment 0.252 1.56E-4 0.01 0.0084 1.0 1425735 TimTec1_003074 CS(=O)(=O)N1CCC(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L17 compound treatment 0.339 0.0872 4.68 4.6836 1.0 3209914 TimTec1_003075 O=C(Nc1ccc(cc1)N2CCCC2)/C=C/c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L18 compound treatment 0.253 0.00116 0.06 0.0621 1.0 3084222 TimTec1_003076 CC(C)C(=O)Nc1ccccc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L19 compound treatment 0.273 0.0212 1.14 1.1369 1.0 1413251 TimTec1_003077 O=C(Oc1ccc(OCc2ccccc2)cc1)c3ccc(cc3)n4cnnn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L20 compound treatment 0.262 0.0102 0.55 0.5458 1.0 3084296 TimTec1_003078 CN(c1ccccc1)S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L21 compound treatment 0.255 0.00316 0.17 0.1696 1.0 1393226 TimTec1_003079 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L22 compound treatment 0.246 -0.00584 -0.31 -0.314 -1.0 3084299 TimTec1_003080 CC(C)NS(=O)(=O)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L23 mock treatment 0.253 0.00116 0.06 0.0621 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 L24 mock treatment 0.237 -0.0148 -0.8 -0.7977 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M01 compound treatment 0.263 0.0112 0.6 0.5995 1.0 3209915 TimTec1_003081 CN(C)c1nc(Nc2ccc(OC(F)(F)F)cc2)nc(NC(C)(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M02 compound treatment 0.518 0.266 14.3 14.3027 1.0 1453611 TimTec1_003082 Fc1ccc(NS(=O)(=O)c2ccc(NC(=O)Nc3ccccc3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M03 compound treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 1354508 TimTec1_003083 Fc1ccccc1NC(=O)OCC2CCCN3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M04 compound treatment 0.301 0.0492 2.64 2.6416 1.0 1291773 TimTec1_003084 COc1ccccc1NCC(=O)NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M05 compound treatment 0.243 -0.00884 -0.48 -0.4752 -1.0 3209916 TimTec1_003085 FC(F)(F)COc1nc(NCCOC2(CC3CC4CC(C3)C2)C4)nc(OCC(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M06 compound treatment 0.255 0.00316 0.17 0.1696 1.0 3084303 TimTec1_003086 Cc1ccccc1OCC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M07 compound treatment 0.256 0.00416 0.22 0.2233 1.0 1483294 TimTec1_003087 Brc1ccc(o1)C(=O)N2CCCC2(C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M08 compound treatment 0.36 0.108 5.81 5.8121 1.0 3209917 TimTec1_003088 CCOC(=O)c1c(C)n(C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M09 compound treatment 0.361 0.109 5.87 5.8658 1.0 1608976 TimTec1_003089 Cc1ccc(CNC(=O)c2ccc(Cl)cc2)c(=S)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M10 compound treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 1134765 TimTec1_003090 Cc1cc(ccc1NC(=O)C2CC2)c3ccc(NC(=O)C4CC4)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M11 compound treatment 0.258 0.00616 0.33 0.3308 1.0 1685257 TimTec1_003091 COc1ccc2[nH]c(C)c(CCNS(=O)(=O)c3c(C)[nH]c(=O)[nH]c3=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M12 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1307859 TimTec1_003092 OC(=O)C1CC(=O)N(Cc2ccccc2)C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M13 compound treatment 0.257 0.00516 0.28 0.2771 1.0 1194234 TimTec1_003093 Nn1c(Cn2ccnc2)nnc1Cn3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M14 compound treatment 0.259 0.00716 0.38 0.3846 1.0 1004097 TimTec1_003094 O=C(Nc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M15 compound treatment 0.273 0.0212 1.14 1.1369 1.0 3209918 TimTec1_003095 OC(=O)CSc1nc(O)c2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M16 compound treatment 0.326 0.0742 3.99 3.985 1.0 1780824 TimTec1_003096 COC(=O)c1c(C)c(sc1N)/C(=C/C#N)/C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M17 compound treatment 0.446 0.194 10.43 10.4336 1.0 3084309 TimTec1_003097 Cc1cc(C)c2C3=NC(NC(=O)N3Nc2n1)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M18 compound treatment 0.32 0.0682 3.66 3.6626 1.0 3209920 TimTec1_003098 CCC(=O)Nc1ccc(C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M19 compound treatment 0.482 0.23 12.37 12.3681 1.0 3209921 TimTec1_003099 CCC(=O)c1ccc2cccc3nc(CC)[nH]c1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M20 compound treatment 0.31 0.0582 3.13 3.1252 1.0 3084311 TimTec1_003100 CSc1nc(N)c(C#N)cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M21 compound treatment 0.281 0.0292 1.57 1.5668 1.0 3084313 TimTec1_003101 FC(F)(F)c1cc(nc(SCCN2CCCCC2)c1C#N)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M22 compound treatment 0.265 0.0132 0.71 0.707 1.0 1363379 TimTec1_003102 Cc1cc(C)n(n1)C(=O)CCC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M23 mock treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 M24 mock treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N01 compound treatment 0.276 0.0242 1.3 1.2981 1.0 1876364 TimTec1_003103 COc1ccc2cc(ccc2c1)C(C)C(=O)OCC(=O)N3CCCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N02 compound treatment 0.261 0.00916 0.49 0.492 1.0 3083298 TimTec1_003104 CCc1ccc(NS(=O)(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N03 compound treatment 0.412 0.16 8.61 8.6065 1.0 3210033 TimTec1_003105 NC(=O)c1c(NC(=O)CCCc2ccccc2)scc1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N04 compound treatment 0.253 0.00116 0.06 0.0621 1.0 3083302 TimTec1_003106 FC(F)(F)c1ccccc1NC(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N05 compound treatment 0.441 0.189 10.16 10.1649 1.0 3210034 TimTec1_003107 NC(=C(C#N)C#N)/C(=C/c1ccc(o1)c2cccc(c2)C(=O)O)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N06 compound treatment 0.302 0.0502 2.7 2.6953 1.0 1611585 TimTec1_003108 COc1ccc(OC)c(NC(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N07 compound treatment 0.314 0.0622 3.34 3.3401 1.0 3210035 TimTec1_003109 COc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N08 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1483126 TimTec1_003110 CCN(C1CCCCC1)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N09 compound treatment 0.378 0.126 6.78 6.7794 1.0 3210036 TimTec1_003111 C/C(=N\N1CCN(CC1)C2c3ccccc3-c4ccccc24)/c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N10 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1438968 TimTec1_003112 COc1ccc(Cl)cc1NS(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N11 compound treatment 0.247 -0.00484 -0.26 -0.2603 -1.0 1569076 TimTec1_003113 Clc1cccc(NC(=O)C2(CCCCC2)NC(=O)Cc3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N12 compound treatment 0.327 0.0752 4.04 4.0387 1.0 3083307 TimTec1_003114 COc1ccc(cc1)S(=O)(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N13 compound treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 1576607 TimTec1_003115 CCC1(CC)OC(Nc2ccccc21)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N14 compound treatment 0.366 0.114 6.13 6.1345 1.0 1306106 TimTec1_003116 COc1ccc(CC(=O)N2CCc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N15 compound treatment 0.367 0.115 6.19 6.1883 1.0 1533234 TimTec1_003117 Oc1ccccc1N2CCN(CC2)C(=O)c3scc4CCCCc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N16 compound treatment 0.242 -0.00984 -0.53 -0.529 -1.0 3083310 TimTec1_003118 CN(Cc1ccccc1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N17 compound treatment 0.264 0.0122 0.65 0.6533 1.0 1242242 TimTec1_003119 O=c1n(CN2CCOCC2)c3ccccc3n1CN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N18 compound treatment 0.248 -0.00384 -0.21 -0.2066 -1.0 1434668 TimTec1_003120 CC(C)C(=O)N(Cc1ccccc1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N19 compound treatment 0.28 0.0282 1.51 1.5131 1.0 1692260 TimTec1_003121 Cc1ccc(NC(=O)c2ccc(Oc3ccc(cc3)C(=O)Nc4ccc(C)cc4)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N20 compound treatment 0.285 0.0332 1.78 1.7817 1.0 1530780 TimTec1_003122 COC(=O)c1cc(NS(=O)(=O)Cc2ccccc2)cc(c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N21 compound treatment 0.253 0.00116 0.06 0.0621 1.0 1642760 TimTec1_003123 O=S(=O)(Nn1cnnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N22 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1190900 TimTec1_003124 COc1ccc(NS(=O)(=O)Cc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N23 mock treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 N24 mock treatment 0.236 -0.0158 -0.85 -0.8514 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O01 compound treatment 0.264 0.0122 0.65 0.6533 1.0 1591566 TimTec1_003125 Nn1cnn(CC(=O)Nc2nccs2)c1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O02 compound treatment 0.276 0.0242 1.3 1.2981 1.0 1667880 TimTec1_003126 Fc1ccc(NC(=O)CCC(=O)Nc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O03 compound treatment 0.252 1.56E-4 0.01 0.0084 1.0 1127183 TimTec1_003127 CN(C)C(=O)NC1CC(C)(C)N(O)C(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O04 compound treatment 0.261 0.00916 0.49 0.492 1.0 3083316 TimTec1_003128 COC(=O)COc1cc(C)ccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O05 compound treatment 0.301 0.0492 2.64 2.6416 1.0 1147462 TimTec1_003129 CN(Cc1nc(cs1)c2ccccc2)C(=O)NC3(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O06 compound treatment 0.277 0.0252 1.35 1.3518 1.0 1412252 TimTec1_003130 Cc1ccccc1OCC(=O)NC2CCCCC2NC(=O)COc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O07 compound treatment 0.254 0.00216 0.12 0.1159 1.0 1038833 TimTec1_003131 Cc1cc(C)c(C(=O)O)c(O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O08 compound treatment 0.284 0.0322 1.73 1.728 1.0 3083333 TimTec1_003132 C/C(=N/O)/c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O09 compound treatment 0.25 -0.00184 -0.1 -0.0991 -1.0 1238150 TimTec1_003133 Cc1ccc(C)c(c1)N2C3CS(=O)(=O)CC3CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O10 compound treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 3083335 TimTec1_003134 Nc1c[n+](no1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O11 compound treatment 0.357 0.105 5.65 5.6509 1.0 3210037 TimTec1_003135 COC(=O)CSc1ccc2c(N)c(sc2c1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O12 compound treatment 0.399 0.147 7.91 7.9079 1.0 1652358 TimTec1_003136 CCC(=O)Nc1ccc(cc1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O13 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1308315 TimTec1_003137 COc1cc2cc3c(=O)oc(nc3nc2cc1OC)c4ccccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O14 compound treatment 0.505 0.253 13.6 13.6041 1.0 1329048 TimTec1_003138 Cc1cc(Br)ccc1OCC(=O)NCCC2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O15 compound treatment 0.46 0.208 11.19 11.1859 1.0 3083338 TimTec1_003139 Oc1nc(SCC(=O)N2CCOCC2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O16 compound treatment 0.369 0.117 6.3 6.2957 1.0 3210038 TimTec1_003140 O/N=C/c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O17 compound treatment 0.392 0.14 7.53 7.5317 1.0 1730029 TimTec1_003141 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)NC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O18 compound treatment 0.26 0.00816 0.44 0.4383 1.0 3083340 TimTec1_003142 N#CC[N+]1(CCN2CC1)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O19 compound treatment 0.262 0.0102 0.55 0.5458 1.0 3083341 TimTec1_003143 CC1(C)C=C(C(=O)N)C(C)(C)N1OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O20 compound treatment 0.496 0.244 13.12 13.1204 1.0 1600220 TimTec1_003144 CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O21 compound treatment 0.299 0.0472 2.53 2.5341 1.0 3083344 TimTec1_003145 CC(C)(C)C(=O)c1sc2nc(cc(c2c1N)C(F)(F)F)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O22 compound treatment 0.257 0.00516 0.28 0.2771 1.0 1287628 TimTec1_003146 COc1ccc(NC(=O)CCC(=O)Oc2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O23 mock treatment 0.265 0.0132 0.71 0.707 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 O24 mock treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P01 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1410014 TimTec1_003147 Clc1ncccc1C(=O)NCCC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P02 compound treatment 0.24 -0.0118 -0.64 -0.6365 -1.0 1029200 TimTec1_003148 CN(C(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P03 compound treatment 0.382 0.13 6.99 6.9943 1.0 3210039 TimTec1_003149 Cc1ccc(C)c(c1)c2csc(NC(=O)CCCc3ccccc3)c2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P04 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1021206 TimTec1_003150 O=C(Cc1ccccc1)NCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P05 compound treatment 0.32 0.0682 3.66 3.6626 1.0 3083347 TimTec1_003151 COC(=O)c1cc(NC(=S)NN(C)C)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P06 compound treatment 0.239 -0.0128 -0.69 -0.6902 -1.0 3210040 TimTec1_003152 CC(C)(C)N(Cc1ccccc1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P07 compound treatment 0.513 0.261 14.03 14.034 1.0 3083349 TimTec1_003153 COc1ccc(CSc2nnc(SCc3ccc(cc3)C(=O)O)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P08 compound treatment 0.457 0.205 11.02 11.0247 1.0 1063128 TimTec1_003154 Cc1ccc(cc1)S(=O)(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P09 compound treatment 0.445 0.193 10.38 10.3798 1.0 3210041 TimTec1_003155 Sc1nnc(c2ccccc2)n1/N=C\c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P10 compound treatment 0.239 -0.0128 -0.69 -0.6902 -1.0 3083351 TimTec1_003156 COc1ccccc1CNS(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P11 compound treatment 0.244 -0.00784 -0.42 -0.4215 -1.0 1530173 TimTec1_003157 CC(C)(C)c1cc(Sc2nc(nc(n2)N3CCOCC3)N4CCOCC4)cc(c1O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P12 compound treatment 0.251 -8.44E-4 -0.05 -0.0453 -1.0 3083353 TimTec1_003158 CCN(CC)S(=O)(=O)c1c(C)cc(C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P13 compound treatment 0.272 0.0202 1.08 1.0832 1.0 1546315 TimTec1_003159 Cc1c(CCNC2=CC(=O)OC32CCCCC3)c4ccccc4n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P14 compound treatment 0.26 0.00816 0.44 0.4383 1.0 1177659 TimTec1_003160 Cc1cccc(c1)C(=O)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P15 compound treatment 0.307 0.0552 2.96 2.964 1.0 3210042 TimTec1_003161 CC(C)c1cc(C)ccc1OCCSc2nc(N)cc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P16 compound treatment 0.24 -0.0118 -0.64 -0.6365 -1.0 3083357 TimTec1_003162 COC(=O)CNC(=O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P17 compound treatment 0.376 0.124 6.67 6.6719 1.0 1308187 TimTec1_003163 Cc1cc(C)n(n1)c2ccc(Cl)c(c2)C(=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P18 compound treatment 0.246 -0.00584 -0.31 -0.314 -1.0 3083360 TimTec1_003164 CC(C)C(=O)N1CCCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P19 compound treatment 0.258 0.00616 0.33 0.3308 1.0 1157157 TimTec1_003165 Cc1ccc(C)n1c2cccc(c2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P20 compound treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1466847 TimTec1_003166 COc1ccccc1N2CCN(CC2)S(=O)(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P21 compound treatment 0.243 -0.00884 -0.48 -0.4752 -1.0 3210043 TimTec1_003167 CC1CCN(CC1)C(=O)c2ccccc2Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P22 compound treatment 0.259 0.00716 0.38 0.3846 1.0 1611033 TimTec1_003168 Cc1ccccc1NS(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P23 mock treatment 0.243 -0.00884 -0.48 -0.4752 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2071 P24 mock treatment 0.249 -0.00284 -0.15 -0.1528 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A01 compound treatment 0.246 -0.00403 -0.22 -0.2167 -1.0 1249702 TimTec1_003169 CC1CCCCN1S(=O)(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A02 compound treatment 0.227 -0.023 -1.24 -1.2377 -1.0 3210166 TimTec1_003170 CCC(C(=O)N(C)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A03 compound treatment 0.255 0.00497 0.27 0.267 1.0 1568702 TimTec1_003171 Cc1ccc(cc1C)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A04 compound treatment 0.219 -0.031 -1.67 -1.6676 -1.0 1300542 TimTec1_003172 O=C(CN1C(=O)c2ccccc2C1=O)NCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A05 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3210167 TimTec1_003173 COc1cccc(c1)C(=O)N(CC=C)CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A06 compound treatment 0.219 -0.031 -1.67 -1.6676 -1.0 3083365 TimTec1_003174 CN(C)S(=O)(=O)NCc1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A07 compound treatment 0.276 0.026 1.4 1.3955 1.0 3083366 TimTec1_003175 CC(=O)N1CCc2ccccc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A08 compound treatment 0.252 0.00197 0.11 0.1057 1.0 3210168 TimTec1_003176 CC1CC(C)CN(C1)C(=O)CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A09 compound treatment 0.242 -0.00803 -0.43 -0.4316 -1.0 1737672 TimTec1_003177 O=C(CC(c1ccccc1)c2ccccc2)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A10 compound treatment 0.226 -0.024 -1.29 -1.2914 -1.0 3083369 TimTec1_003178 CCN(C(=O)CC(C)(C)C)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A11 compound treatment 0.354 0.104 5.59 5.587 1.0 1464313 TimTec1_003179 CCc1ccc(NC(=O)c2ccc3OCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A12 compound treatment 0.228 -0.022 -1.18 -1.184 -1.0 1608343 TimTec1_003180 COc1cc(SC)ccc1C(=O)Nc2ccccc2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A13 compound treatment 0.335 0.085 4.57 4.566 1.0 1728662 TimTec1_003181 CC(=O)Nc1ccc(NC(=O)CC(c2ccccc2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A14 compound treatment 0.232 -0.018 -0.97 -0.969 -1.0 1565572 TimTec1_003182 CCOC(=O)C1CCCN(C1)C(=O)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A15 compound treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 1573195 TimTec1_003183 CC(C)c1ccc(NS(=O)(=O)Cc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A16 compound treatment 0.236 -0.014 -0.75 -0.7541 -1.0 1133863 TimTec1_003184 COCC(C)NC(=O)c1ccc(NC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A17 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1299790 TimTec1_003185 CC(Oc1ccccc1)C(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A18 compound treatment 0.492 0.242 13.0 13.0028 1.0 1542766 TimTec1_003186 CCOC(=O)c1cccc(NC(=O)CCc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A19 compound treatment 0.337 0.087 4.67 4.6735 1.0 1681120 TimTec1_003187 CCC(C)C(=O)N1CCN(CC1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A20 compound treatment 0.288 0.038 2.04 2.0403 1.0 3210169 TimTec1_003188 Cn1nc(cc1C(=O)O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A21 compound treatment 0.285 0.035 1.88 1.8791 1.0 3083375 TimTec1_003189 CCC(C)C(=O)Nc1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A22 compound treatment 0.501 0.251 13.49 13.4865 1.0 1652746 TimTec1_003190 COc1ccc(cc1)C2C=C(NC(=O)C2C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A23 mock treatment 0.264 0.014 0.75 0.7506 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 A24 mock treatment 0.28 0.03 1.61 1.6104 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B01 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 1388587 TimTec1_003191 O=S(=O)(NCCN1CCOCC1)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B02 compound treatment 0.38 0.13 6.98 6.9842 1.0 1707122 TimTec1_003192 COc1cc(cc(Cl)c1O)C2CSc3nc4sc5CCCCc5c4c(=O)n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B03 compound treatment 0.275 0.025 1.34 1.3417 1.0 1004002 TimTec1_003193 Nc1ccc(I)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B04 compound treatment 0.237 -0.013 -0.7 -0.7003 -1.0 1150946 TimTec1_003194 O=C1CC(C2COC1O2)N3c4cccc5cccc(c45)S3(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B05 compound treatment 0.265 0.015 0.8 0.8043 1.0 1120723 TimTec1_003195 CC(=O)Nc1cccc(OC(=O)c2ccoc2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B06 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 1185449 TimTec1_003196 CCCC(C(=O)N)C1=NC2(CCCCC2)Cc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B07 compound treatment 0.427 0.177 9.51 9.5099 1.0 3083393 TimTec1_003197 Fc1ccc(CSc2nnc(SCc3ccccc3)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B08 compound treatment 0.282 0.032 1.72 1.7179 1.0 3210170 TimTec1_003198 OC(=O)c1ccc(/C=N/N2C(=O)c3cccc4cccc(C2=O)c34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B09 compound treatment 0.258 0.00797 0.43 0.4282 1.0 3083394 TimTec1_003199 FC(F)(F)C(NC(=O)c1ccco1)(NC2=NCCS2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B10 compound treatment 0.24 -0.01 -0.54 -0.5391 -1.0 3210171 TimTec1_003200 Cc1nn(C)c(C)c1/C=C/C(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B11 compound treatment 0.379 0.129 6.93 6.9305 1.0 3210172 TimTec1_003201 COc1ccc(cc1)C2=C(Nc3ccc(cc3)C(=O)N4CCOCC4)c5ccccc5C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B12 compound treatment 0.284 0.034 1.83 1.8254 1.0 1429954 TimTec1_003202 CC(=O)ON1C(=O)c2cccc3c(Br)ccc(C1=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B13 compound treatment 0.239 -0.011 -0.59 -0.5929 -1.0 1329559 TimTec1_003203 COC(=O)c1ccccc1N(C)C(=O)c2cccc(c2)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B14 compound treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1642501 TimTec1_003204 CC(C)c1ccc(Nc2nc(nc(n2)N3CCCCC3)N4CCCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B15 compound treatment 0.219 -0.031 -1.67 -1.6676 -1.0 3083396 TimTec1_003205 CC/N=C/1\SC(CC(=O)N1CC)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B16 compound treatment 0.443 0.193 10.37 10.3697 1.0 1410726 TimTec1_003206 COc1cccc(c1)c2nnc(SCc3ccc(cc3)C(=O)O)n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B17 compound treatment 0.232 -0.018 -0.97 -0.969 -1.0 3083397 TimTec1_003207 FC(F)(F)c1cccc(c1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B18 compound treatment 0.327 0.077 4.14 4.1361 1.0 3210173 TimTec1_003208 COC(=O)c1ccc(/C=C/2\SC(=N)NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B19 compound treatment 0.256 0.00597 0.32 0.3207 1.0 3210174 TimTec1_003209 OC1(CC(NO1)c2ccccc2)C3(O)CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B20 compound treatment 0.259 0.00897 0.48 0.4819 1.0 1622985 TimTec1_003210 O=C1C2CC=CCC2C(=O)N1C3CC(=O)C4OCC3O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B21 compound treatment 0.511 0.261 14.02 14.0239 1.0 1582803 TimTec1_003211 Nn1c(COc2ccc(Cl)cc2)nc3ccccc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B22 compound treatment 0.344 0.094 5.05 5.0496 1.0 3083401 TimTec1_003212 OC(=O)CCc1nn2c3ccccc3nc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B23 mock treatment 0.238 -0.012 -0.65 -0.6466 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 B24 mock treatment 0.239 -0.011 -0.59 -0.5929 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C01 compound treatment 0.555 0.305 16.39 16.3883 1.0 1543604 TimTec1_003213 O=S(=O)(Cc1ccccc1)Nc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C02 compound treatment 0.279 0.029 1.56 1.5567 1.0 3083402 TimTec1_003214 CN(C(=O)Cc1cccs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C03 compound treatment 0.27 0.02 1.07 1.073 1.0 1605314 TimTec1_003215 CCCNC(=O)c1ccc(OCC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C04 compound treatment 0.246 -0.00403 -0.22 -0.2167 -1.0 1295085 TimTec1_003216 O=C(COc1ccccc1)N(Cc2ccccc2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C05 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 3083405 TimTec1_003217 COc1cccc(c1)C(=O)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C06 compound treatment 0.242 -0.00803 -0.43 -0.4316 -1.0 3210175 TimTec1_003218 CC(C)CC(=O)NCc1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C07 compound treatment 0.268 0.018 0.97 0.9655 1.0 3083407 TimTec1_003219 CCCNC(=O)c1ccccc1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C08 compound treatment 0.329 0.079 4.24 4.2436 1.0 3210176 TimTec1_003220 CCN(C(=O)CCc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C09 compound treatment 0.275 0.025 1.34 1.3417 1.0 1655477 TimTec1_003221 O=C(CC(c1ccccc1)c2ccccc2)Nc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C10 compound treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 1506281 TimTec1_003222 COc1cc(NC(=O)CC(C)(C)C)c(OC)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C11 compound treatment 0.265 0.015 0.8 0.8043 1.0 1163628 TimTec1_003223 CCN(CC)C(=O)C1c2ccccc2Oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C12 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3083410 TimTec1_003224 CCC(C)C(=O)NCCc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C13 compound treatment 0.243 -0.00703 -0.38 -0.3779 -1.0 3210177 TimTec1_003225 CCOc1ccc(cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C14 compound treatment 0.237 -0.013 -0.7 -0.7003 -1.0 3083413 TimTec1_003226 COCC(C)NC(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C15 compound treatment 0.239 -0.011 -0.59 -0.5929 -1.0 3210178 TimTec1_003227 CC(C)CCNC(=O)c1ccccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C16 compound treatment 0.259 0.00897 0.48 0.4819 1.0 1703463 TimTec1_003228 COCC(C)NC(=O)c1ccc(OC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C17 compound treatment 0.271 0.021 1.13 1.1268 1.0 1178243 TimTec1_003229 CCC(C(=O)NCc1ccccn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C18 compound treatment 0.311 0.061 3.28 3.2763 1.0 1572580 TimTec1_003230 CCOC(=O)C1CCCN(C1)C(=O)CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C19 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 3083416 TimTec1_003231 CC(C)N(Cc1ccccc1)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C20 compound treatment 0.317 0.067 3.6 3.5987 1.0 1144496 TimTec1_003232 C=CCN(CC=C)C(=O)C1c2ccccc2Oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C21 compound treatment 0.321 0.071 3.81 3.8137 1.0 3083418 TimTec1_003233 Brc1ccc(CC(=O)N(CC=C)CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C22 compound treatment 0.393 0.143 7.68 7.6828 1.0 1605852 TimTec1_003234 CCOC(=O)N1CCN(CC1)c2ccc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C23 mock treatment 0.257 0.00697 0.37 0.3744 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 C24 mock treatment 0.257 0.00697 0.37 0.3744 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D01 compound treatment 0.479 0.229 12.3 12.3042 1.0 3083420 TimTec1_003235 Cc1cccc(C)c1NC(=O)CCCSc2nnnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D02 compound treatment 0.264 0.014 0.75 0.7506 1.0 1267320 TimTec1_003236 O=C1CC(C2COC1O2)n3nc(Nc4ccccc4)n(c5ccccc5)c3=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D03 compound treatment 0.244 -0.00603 -0.32 -0.3242 -1.0 3083422 TimTec1_003237 CN1[C@@H]([C@H](CC1=O)C(=O)O)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D04 compound treatment 0.256 0.00597 0.32 0.3207 1.0 3210297 TimTec1_003238 Cc1[nH]c2ccccc2c1CCNCC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D05 compound treatment 0.255 0.00497 0.27 0.267 1.0 1689355 TimTec1_003239 COc1ccc(NC(=O)NC2c3ccccc3Oc4ccccc24)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D06 compound treatment 0.313 0.063 3.38 3.3838 1.0 3083425 TimTec1_003240 Cc1nnc(c2ccccc2)c(=O)n1/N=C/c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D07 compound treatment 0.287 0.037 1.99 1.9866 1.0 1601274 TimTec1_003241 Cc1ccc(cc1)n2c(SCC(=O)N)nc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D08 compound treatment 0.246 -0.00403 -0.22 -0.2167 -1.0 1532590 TimTec1_003242 C(NC1CCCCC1)c2cccn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D09 compound treatment 0.257 0.00697 0.37 0.3744 1.0 3210298 TimTec1_003243 NNc1nc(NN)nc(Nc2cccc(c2)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D10 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3083428 TimTec1_003244 Cc1cc(n2ncnc2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D11 compound treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 3210299 TimTec1_003245 NC1=C(C#N)C(C2=C(CCC2)N1c3sc4CCCCc4c3C#N)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D12 compound treatment 0.26 0.00997 0.54 0.5356 1.0 3083430 TimTec1_003246 COc1ccc(cc1)C2CC(=NO2)C3(C)CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D13 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1610817 TimTec1_003247 CCC1OC(=Nc2ccccc12)c3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D14 compound treatment 0.544 0.294 15.8 15.7972 1.0 3083432 TimTec1_003248 Cc1ccc(CCSc2ccc(Cl)c(Cl)c2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D15 compound treatment 0.238 -0.012 -0.65 -0.6466 -1.0 3210300 TimTec1_003249 Cc1c(CCNC(NC(=O)c2ccc(Cl)cc2)(C(F)(F)F)C(F)(F)F)c3ccccc3n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D16 compound treatment 0.485 0.235 12.63 12.6267 1.0 3083457 TimTec1_003250 Brc1ccc(CSc2nccn2Cc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D17 compound treatment 0.398 0.148 7.95 7.9515 1.0 1520066 TimTec1_003251 CC1CCCN(C1C)S(=O)(=O)c2cccc3c(cccc23)S(=O)(=O)N4CCCC(C)C4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D18 compound treatment 0.456 0.206 11.07 11.0683 1.0 3083459 TimTec1_003252 NC(=O)SCC(=O)Nc1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D19 compound treatment 0.358 0.108 5.8 5.802 1.0 3210301 TimTec1_003253 Nc1cc(=O)[nH]c(S/C=C/c2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D20 compound treatment 0.28 0.03 1.61 1.6104 1.0 3083461 TimTec1_003254 C=CCS/C(=N\n1cnc2ccccc2c1=O)/N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D21 compound treatment 0.276 0.026 1.4 1.3955 1.0 1275489 TimTec1_003255 CCOC(=O)C1=C(NC(=O)C(C#N)C21CCCCC2)SCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D22 compound treatment 0.56 0.31 16.66 16.657 1.0 1429911 TimTec1_003256 O=C(CSc1nc2ccccc2s1)Nc3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D23 mock treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 D24 mock treatment 0.246 -0.00403 -0.22 -0.2167 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E01 compound treatment 0.394 0.144 7.74 7.7365 1.0 1553246 TimTec1_003257 Brc1cccc(c1)C(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E02 compound treatment 0.253 0.00297 0.16 0.1595 1.0 3083464 TimTec1_003258 CN(C)S(=O)(=O)N(C)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E03 compound treatment 0.257 0.00697 0.37 0.3744 1.0 1180821 TimTec1_003259 CCOc1ccc(cc1)C(=O)NC(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E04 compound treatment 0.344 0.094 5.05 5.0496 1.0 1212826 TimTec1_003260 CCOC(=O)C1CCN(CC1)C(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E05 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3210302 TimTec1_003261 CCN(CC)C(=O)c1cccc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E06 compound treatment 0.255 0.00497 0.27 0.267 1.0 3210303 TimTec1_003262 CCCC(C)C(=O)NCc1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E07 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1476178 TimTec1_003263 CC1CC(C)CN(C1)C(=O)c2ccccc2OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E08 compound treatment 0.373 0.123 6.61 6.608 1.0 3210304 TimTec1_003264 CCN(C1CCCCC1)C(=O)CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E09 compound treatment 0.263 0.013 0.7 0.6969 1.0 1131761 TimTec1_003265 COc1ccccc1CC(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E10 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 1709116 TimTec1_003266 CC(C)(C)CC(=O)NCc1ccc(cc1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E11 compound treatment 0.266 0.016 0.86 0.8581 1.0 1613437 TimTec1_003267 O=C(NC1CCCC1)C2c3ccccc3Oc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E12 compound treatment 0.262 0.012 0.64 0.6431 1.0 1434161 TimTec1_003268 CCCC(C)C(=O)Nc1ccc(cc1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E13 compound treatment 0.29 0.04 2.15 2.1478 1.0 1616704 TimTec1_003269 NC(=O)c1ccccc1NC(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E14 compound treatment 0.246 -0.00403 -0.22 -0.2167 -1.0 1260520 TimTec1_003270 CCOC(=O)C1CCCN(C1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E15 compound treatment 0.263 0.013 0.7 0.6969 1.0 3083469 TimTec1_003271 CC(C)CCNC(=O)c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E16 compound treatment 0.253 0.00297 0.16 0.1595 1.0 1590237 TimTec1_003272 CCC(CC)NC(=O)Cc1ccccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E17 compound treatment 0.264 0.014 0.75 0.7506 1.0 1731442 TimTec1_003273 CC(C)(C)CC(=O)NCc1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E18 compound treatment 0.265 0.015 0.8 0.8043 1.0 1659601 TimTec1_003274 CCOC(=O)c1cccc(NC(=O)C(C)(C)CC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E19 compound treatment 0.369 0.119 6.39 6.3931 1.0 1275025 TimTec1_003275 CC(C)N(Cc1ccccc1)C(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E20 compound treatment 0.255 0.00497 0.27 0.267 1.0 1917477 TimTec1_003276 CC(=O)N1[C@@H](CS[C@@H]1c2ccc(F)cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E21 compound treatment 0.261 0.011 0.59 0.5894 1.0 3210305 TimTec1_003277 CC(NS(=O)(=O)N(C)C)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E22 compound treatment 0.515 0.265 14.24 14.2388 1.0 1301346 TimTec1_003278 CC(=O)Nc1ccc(OS(=O)Nc2nnc(C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E23 mock treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 E24 mock treatment 0.264 0.014 0.75 0.7506 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F01 compound treatment 0.27 0.02 1.07 1.073 1.0 3210306 TimTec1_003279 COc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F02 compound treatment 0.259 0.00897 0.48 0.4819 1.0 3210307 TimTec1_003280 CCC(NS(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F03 compound treatment 0.254 0.00397 0.21 0.2132 1.0 1357383 TimTec1_003281 CC(=CCNc1ncnc2nc[nH]c12)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F04 compound treatment 0.277 0.027 1.45 1.4492 1.0 1458922 TimTec1_003282 COc1ccc(CCNC(=O)Cc2c(SC)c3ccccc3n2Cc4ccccc4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F05 compound treatment 0.458 0.208 11.18 11.1758 1.0 3210308 TimTec1_003283 CC(C)(C)N1C(=O)NC(=O)/C(=C/c2cc3ccccc3[nH]2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F06 compound treatment 0.26 0.00997 0.54 0.5356 1.0 1611563 TimTec1_003284 Cc1cc(c2ncccc2c1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F07 compound treatment 0.261 0.011 0.59 0.5894 1.0 1415079 TimTec1_003285 Cc1ccc(cc1)n2c(SCC(=O)Nc3c(C)cccc3C)nc4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F08 compound treatment 0.522 0.272 14.61 14.615 1.0 1631498 TimTec1_003286 COC(=O)c1ccc2nc(NC(=O)CN3C(=O)CCC3=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F09 compound treatment 0.268 0.018 0.97 0.9655 1.0 1658377 TimTec1_003287 C1CC1C#CC(N2CCOCC2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F10 compound treatment 0.337 0.087 4.67 4.6735 1.0 1133097 TimTec1_003288 COC(=O)CNS(=O)(=O)c1ccc(I)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F11 compound treatment 0.259 0.00897 0.48 0.4819 1.0 3210422 TimTec1_003289 COc1ccc(/C=C\2/C3CCC(C)(C2=O)C3(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F12 compound treatment 0.305 0.055 2.95 2.9539 1.0 1395696 TimTec1_003290 CCOC(=O)Oc1c(Cl)cc2oc(=O)sc2c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F13 compound treatment 0.426 0.176 9.46 9.4561 1.0 1432636 TimTec1_003291 Clc1ccc(cc1)C(=O)CCNc2ccc(Cc3ccncc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F14 compound treatment 0.328 0.078 4.19 4.1898 1.0 3083482 TimTec1_003292 CC(=O)N/C(=C/c1ccccc1)/C(=O)Nc2ccc(I)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F15 compound treatment 0.437 0.187 10.05 10.0473 1.0 1541061 TimTec1_003293 Cn1c(SCc2ccc3OCOc3c2)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F16 compound treatment 0.315 0.065 3.49 3.4912 1.0 1611110 TimTec1_003294 O=C(CSc1nc2ccccc2o1)OCC(=O)N3c4ccccc4Sc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F17 compound treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1592970 TimTec1_003295 CC(C)CSc1cc(cc(c1C)S(=O)(=O)c2ccccc2)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F18 compound treatment 0.266 0.016 0.86 0.8581 1.0 1602870 TimTec1_003296 CC1CCCCN1S(=O)(=O)c2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F19 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1517220 TimTec1_003297 CCC(NS(=O)(=O)c1cc(C)ccc1OC)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F20 compound treatment 0.481 0.231 12.41 12.4117 1.0 3083487 TimTec1_003298 Fc1ccc(COc2cccc(/C=C/3\NC(=S)NC3=O)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F21 compound treatment 0.39 0.14 7.52 7.5216 1.0 1551647 TimTec1_003299 CCCc1nnc(s1)N(Cc2ccc(Cl)cc2)C(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F22 compound treatment 0.234 -0.016 -0.86 -0.8615 -1.0 3083489 TimTec1_003300 FC(F)(F)c1nc(SCc2ccccc2)c(C#N)cc1C(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F23 mock treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 F24 mock treatment 0.237 -0.013 -0.7 -0.7003 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G01 compound treatment 0.446 0.196 10.53 10.5309 1.0 1314654 TimTec1_003301 COc1ccc(CNC(=O)c2ccc(OC)cc2OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G02 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 1658255 TimTec1_003302 COc1cc(SC)ccc1C(=O)N(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G03 compound treatment 0.28 0.03 1.61 1.6104 1.0 1190937 TimTec1_003303 CCOc1ccc(cc1)C(=O)N2CC(C)CC(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G04 compound treatment 0.262 0.012 0.64 0.6431 1.0 3083492 TimTec1_003304 CCCC(C)C(=O)Nc1cccc(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G05 compound treatment 0.266 0.016 0.86 0.8581 1.0 3083496 TimTec1_003305 CCNC(=O)c1cccc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G06 compound treatment 0.314 0.064 3.44 3.4375 1.0 3210423 TimTec1_003306 COc1cc(SC)ccc1C(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G07 compound treatment 0.269 0.019 1.02 1.0193 1.0 1444060 TimTec1_003307 CC(=O)Oc1ccccc1C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G08 compound treatment 0.252 0.00197 0.11 0.1057 1.0 1696246 TimTec1_003308 CCC(C(=O)Nc1ccc(cc1)S(=O)(=O)N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G09 compound treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1723016 TimTec1_003309 O=C(NCCN1CCOCC1)c2ccccc2Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G10 compound treatment 0.244 -0.00603 -0.32 -0.3242 -1.0 3210424 TimTec1_003310 CN(C)S(=O)(=O)Nc1ccccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G11 compound treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 1134633 TimTec1_003311 CCN(Cc1ccccc1)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G12 compound treatment 0.237 -0.013 -0.7 -0.7003 -1.0 1547792 TimTec1_003312 CCCC(C)C(=O)Nc1ccc(NC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G13 compound treatment 0.339 0.089 4.78 4.7809 1.0 3083508 TimTec1_003313 NC(=O)c1ccccc1NC(=O)c2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G14 compound treatment 0.276 0.026 1.4 1.3955 1.0 1361334 TimTec1_003314 COCC(C)NS(=O)(=O)c1c(C)cc(C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G15 compound treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 1303565 TimTec1_003315 CC(C)CCNS(=O)(=O)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G16 compound treatment 0.47 0.22 11.82 11.8206 1.0 1132078 TimTec1_003316 NS(=O)(=O)c1ccc(CCNC(=O)CC(c2ccccc2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G17 compound treatment 0.275 0.025 1.34 1.3417 1.0 3084684 TimTec1_003317 Cc1cc(C)cc(NC(=O)Cc2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G18 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 3084685 TimTec1_003318 CCC(C)(C)C(=O)N1CCC(CC1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G19 compound treatment 0.255 0.00497 0.27 0.267 1.0 1406144 TimTec1_003319 CC(Oc1ccccc1)C(=O)NC2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G20 compound treatment 0.328 0.078 4.19 4.1898 1.0 3210425 TimTec1_003320 Cc1ccc(cc1)c2nc3sc4nc5ccccc5nc4n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G21 compound treatment 0.259 0.00897 0.48 0.4819 1.0 1483366 TimTec1_003321 CCCC(C)C(=O)NCc1ccccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G22 compound treatment 0.474 0.224 12.04 12.0356 1.0 1622726 TimTec1_003322 O=C(NCCc1nc2ccccc2[nH]1)C3COc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G23 mock treatment 0.264 0.014 0.75 0.7506 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 G24 mock treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H01 compound treatment 0.236 -0.014 -0.75 -0.7541 -1.0 3084686 TimTec1_003323 FC(F)(F)c1ccc(COc2ccc3cc(c4ccccn4)c(=O)oc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H02 compound treatment 0.261 0.011 0.59 0.5894 1.0 1383752 TimTec1_003324 OC1(CC(=O)C2CC3CC2C=C3)C(=O)Nc4ccccc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H03 compound treatment 0.309 0.059 3.17 3.1688 1.0 3084687 TimTec1_003325 CCOC(=O)c1cc(C(=O)OCC)n(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H04 compound treatment 0.264 0.014 0.75 0.7506 1.0 3210426 TimTec1_003326 Cc1ccccc1n2c(CSC(=N)N)nc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H05 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3084688 TimTec1_003327 O=C(N/C=N/C(=O)c1cccnc1)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H06 compound treatment 0.26 0.00997 0.54 0.5356 1.0 1564884 TimTec1_003328 CN1CCN(CC1)S(=O)(=O)c2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H07 compound treatment 0.355 0.105 5.64 5.6407 1.0 3210427 TimTec1_003329 Cc1ccc(cc1)n2c(SCC(=O)C(C)(C)C)nnc2c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H08 compound treatment 0.278 0.028 1.5 1.5029 1.0 3084689 TimTec1_003330 Nc1nc(SCC#N)c(C#N)c(c1C#N)c2cccc(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H09 compound treatment 0.252 0.00197 0.11 0.1057 1.0 3210428 TimTec1_003331 CCC(=O)NC(Nc1sc2CCCc2c1C(=O)OC)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H10 compound treatment 0.41 0.16 8.6 8.5963 1.0 3084690 TimTec1_003332 Cc1noc(c1I)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H11 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3084691 TimTec1_003333 NC1=C(C#N)C(NN1c2ccccc2)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H12 compound treatment 0.434 0.184 9.89 9.886 1.0 1616513 TimTec1_003334 Ic1ccc(NC(=O)CC2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H13 compound treatment 0.387 0.137 7.36 7.3604 1.0 3210429 TimTec1_003335 Cc1cc(C)c(C#N)c(SCSc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H14 compound treatment 0.308 0.058 3.12 3.1151 1.0 3084692 TimTec1_003336 Cn1nnnc1SCC(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H15 compound treatment 0.366 0.116 6.23 6.2319 1.0 3210430 TimTec1_003337 Cc1ccc(cc1)C(=O)OCC2OC(O)C(O)C2OC(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H16 compound treatment 0.265 0.015 0.8 0.8043 1.0 1327025 TimTec1_003338 CC1C2CC(CC1(C)C)N(C2)C(=O)c3ccc(cc3)N4C(=O)c5ccccc5C4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H17 compound treatment 0.256 0.00597 0.32 0.3207 1.0 3084693 TimTec1_003339 COc1ccc2nc(N3CCCCC3)c(/C=C/4\N=C(OC4=O)c5ccccc5)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H18 compound treatment 0.403 0.153 8.22 8.2202 1.0 3210431 TimTec1_003340 O=c1[nH]c(CN2CCCCC2)nc3c4ccccc4oc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H19 compound treatment 0.255 0.00497 0.27 0.267 1.0 1074832 TimTec1_003341 OC(=O)CCN1CCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H20 compound treatment 0.349 0.099 5.32 5.3183 1.0 3210432 TimTec1_003342 O=C1CC(S/C(=N/c2ccccc2)/Nc3ccccc3)C(=O)N1CCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H21 compound treatment 0.336 0.086 4.62 4.6197 1.0 3084694 TimTec1_003343 COC(=O)C(CC(=O)c1ccc(Br)cc1)(Cc2ccc(Br)cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H22 compound treatment 0.394 0.144 7.74 7.7365 1.0 3210433 TimTec1_003344 CC/C(=C\C(=O)c1ccc(Br)cc1)/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H23 mock treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 H24 mock treatment 0.242 -0.00803 -0.43 -0.4316 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I01 compound treatment 0.311 0.061 3.28 3.2763 1.0 1172830 TimTec1_003345 COc1ccc(cc1OC)C(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I02 compound treatment 0.265 0.015 0.8 0.8043 1.0 3210434 TimTec1_003346 CCN(CC)C(=O)Cc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I03 compound treatment 0.276 0.026 1.4 1.3955 1.0 1474996 TimTec1_003347 CCOc1ccccc1NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I04 compound treatment 0.233 -0.017 -0.92 -0.9153 -1.0 1142378 TimTec1_003348 COc1ccc(CNS(=O)(=O)N(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I05 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3210550 TimTec1_003349 COc1cccc(c1)C(=O)N2CCCCC2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I06 compound treatment 0.314 0.064 3.44 3.4375 1.0 1492690 TimTec1_003350 COc1ccccc1NC(=O)Cc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I07 compound treatment 0.235 -0.015 -0.81 -0.8078 -1.0 3210551 TimTec1_003351 CN(C)C(=O)c1ccccc1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I08 compound treatment 0.296 0.046 2.47 2.4702 1.0 3084695 TimTec1_003352 O=C(Cc1cccs1)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I09 compound treatment 0.273 0.023 1.23 1.2342 1.0 1220667 TimTec1_003353 COC(=O)c1ccccc1NC(=O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I10 compound treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 3084696 TimTec1_003354 CCN(C1CCCCC1)C(=O)CC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I11 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 1615201 TimTec1_003355 CCCCC(CC)C(=O)Nc1cc(OC)ccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I12 compound treatment 0.253 0.00297 0.16 0.1595 1.0 1644031 TimTec1_003356 CCCC(C)C(=O)NCc1ccncc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I13 compound treatment 0.307 0.057 3.06 3.0613 1.0 1727106 TimTec1_003357 NC(=O)c1ccccc1NC(=O)CC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I14 compound treatment 0.242 -0.00803 -0.43 -0.4316 -1.0 1241961 TimTec1_003358 COCC(C)NS(=O)(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I15 compound treatment 0.257 0.00697 0.37 0.3744 1.0 3210552 TimTec1_003359 CC(C)(C)NC(=O)Cc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I16 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 1125244 TimTec1_003360 CCC(CC)NC(=O)c1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I17 compound treatment 0.242 -0.00803 -0.43 -0.4316 -1.0 3084697 TimTec1_003361 CCC(C)(C)C(=O)Nc1cc(C)cc(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I18 compound treatment 0.261 0.011 0.59 0.5894 1.0 1302744 TimTec1_003362 CCC(C)(C)C(=O)NCc1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I19 compound treatment 0.314 0.064 3.44 3.4375 1.0 3084700 TimTec1_003363 Brc1ccc(CC(=O)Nc2nccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I20 compound treatment 0.238 -0.012 -0.65 -0.6466 -1.0 3210553 TimTec1_003364 Cc1nn(c2OC(=C(C#N)C(c12)(C(F)(F)F)C(F)(F)F)N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I21 compound treatment 0.28 0.03 1.61 1.6104 1.0 1183466 TimTec1_003365 COc1ccccc1CNC(=O)C(C)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I22 compound treatment 0.301 0.051 2.74 2.7389 1.0 1258450 TimTec1_003366 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccc(Oc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I23 mock treatment 0.255 0.00497 0.27 0.267 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 I24 mock treatment 0.27 0.02 1.07 1.073 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J01 compound treatment 0.283 0.033 1.77 1.7716 1.0 1010972 TimTec1_003367 C(Cc1ccccn1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J02 compound treatment 0.264 0.014 0.75 0.7506 1.0 1550058 TimTec1_003368 CC1(OC(=N)C2(C#N)C1c3ccccc3)OC(c4ccccc4)C2(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J03 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 3084706 TimTec1_003369 OC(=O)c1ccn(COc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J04 compound treatment 0.379 0.129 6.93 6.9305 1.0 1414868 TimTec1_003370 Oc1c(oc2ccccc2c1=O)c3ccc(F)c(Oc4ccccc4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J05 compound treatment 0.283 0.033 1.77 1.7716 1.0 3084708 TimTec1_003371 Cc1nnc(o1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J06 compound treatment 0.317 0.067 3.6 3.5987 1.0 1397012 TimTec1_003372 OC(=O)c1cn(C2CC2)c3cc(N4CCN(CC4)C(=S)S)c(F)cc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J07 compound treatment 0.262 0.012 0.64 0.6431 1.0 1297192 TimTec1_003373 CCOc1ccc(cc1)n2c(SCC(=O)N)nc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J08 compound treatment 0.397 0.147 7.9 7.8977 1.0 3210554 TimTec1_003374 Cc1ccc(Cl)cc1NCN2C(=O)/C(=C/c3ccc(Br)cc3)/NC2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J09 compound treatment 0.355 0.105 5.64 5.6407 1.0 1683010 TimTec1_003375 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)Nc4ncccc4C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J10 compound treatment 0.279 0.029 1.56 1.5567 1.0 1172443 TimTec1_003376 Oc1c(Br)cc(Br)cc1C(=O)CSC(=S)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J11 compound treatment 0.36 0.11 5.91 5.9094 1.0 3210555 TimTec1_003377 CCn1c(NC(=O)COc2cccc(c2)C(F)(F)F)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J12 compound treatment 0.295 0.045 2.42 2.4165 1.0 3084740 TimTec1_003378 CC1CN(C)C(C)/C(=C\c2ccco2)/C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J13 compound treatment 0.298 0.048 2.58 2.5777 1.0 1131053 TimTec1_003379 Cc1ccc(cc1)c2nc3ccc(NCc4cccs4)cc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J14 compound treatment 0.47 0.22 11.82 11.8206 1.0 3210556 TimTec1_003380 COc1ccc(cc1)C(=O)CSc2nn3c(SCC(=O)c4ccc(OC)cc4)nnc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J15 compound treatment 0.252 0.00197 0.11 0.1057 1.0 1251084 TimTec1_003381 C1Cc2cn(cc2CCc3cn(cc13)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J16 compound treatment 0.47 0.22 11.82 11.8206 1.0 1180362 TimTec1_003382 O=C(CSC1=NCCS1)Nc2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J17 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 1305573 TimTec1_003383 CCCc1c(C)nc2c(C)cccc2c1SCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J18 compound treatment 0.267 0.017 0.91 0.9118 1.0 1123163 TimTec1_003384 CCN(CC)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J19 compound treatment 0.386 0.136 7.31 7.3066 1.0 1426086 TimTec1_003385 OC(CSc1ncnc2[nH]cnc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J20 compound treatment 0.384 0.134 7.2 7.1991 1.0 3210557 TimTec1_003386 NC(=O)/C(=C/1\C(=O)Nc2ccc(Br)cc12)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J21 compound treatment 0.219 -0.031 -1.67 -1.6676 -1.0 3084745 TimTec1_003387 Oc1c(ccc2cccnc12)C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J22 compound treatment 0.258 0.00797 0.43 0.4282 1.0 1595988 TimTec1_003388 CCOC(=O)c1[nH]c(=O)[nH]c1COC(=O)CNC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J23 mock treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 J24 mock treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K01 compound treatment 0.285 0.035 1.88 1.8791 1.0 1244666 TimTec1_003389 COc1ccc(cc1OC)C(=O)N2CCC(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K02 compound treatment 0.26 0.00997 0.54 0.5356 1.0 3210558 TimTec1_003390 CCN(CC)C(=O)Cc1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K03 compound treatment 0.254 0.00397 0.21 0.2132 1.0 1215547 TimTec1_003391 O=C(N(CC#N)CC#N)c1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K04 compound treatment 0.238 -0.012 -0.65 -0.6466 -1.0 3210559 TimTec1_003392 CCc1ccccc1NC(=O)C(C)(C)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K05 compound treatment 0.431 0.181 9.72 9.7248 1.0 1650684 TimTec1_003393 O=C(NCC#N)c1ccc(cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K06 compound treatment 0.264 0.014 0.75 0.7506 1.0 3210560 TimTec1_003394 CC1CN(CC(C)O1)C(=O)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K07 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3084750 TimTec1_003395 CNC(=O)c1ccc(cc1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K08 compound treatment 0.297 0.047 2.52 2.5239 1.0 3210561 TimTec1_003396 CCc1ccc(NC(=O)Cc2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K09 compound treatment 0.255 0.00497 0.27 0.267 1.0 1267949 TimTec1_003397 CC(NC(=O)c1ccc2OCOc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K10 compound treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 3084752 TimTec1_003398 CC(C)CC(=O)Nc1ccccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K11 compound treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1245827 TimTec1_003399 CCOc1ccccc1C(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K12 compound treatment 0.39 0.14 7.52 7.5216 1.0 1351900 TimTec1_003400 CC(Oc1ccccc1)C(=O)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K13 compound treatment 0.284 0.034 1.83 1.8254 1.0 1440169 TimTec1_003401 CC(=O)Oc1ccccc1C(=O)Nc2ccc(cc2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K14 compound treatment 0.254 0.00397 0.21 0.2132 1.0 1291221 TimTec1_003402 CCOC(=O)C1CCCN(C1)C(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K15 compound treatment 0.286 0.036 1.93 1.9328 1.0 1346285 TimTec1_003403 O=C(Cc1cccs1)N2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K16 compound treatment 0.265 0.015 0.8 0.8043 1.0 1313407 TimTec1_003404 CCOC(=O)C1CCCN(C1)C(=O)c2ccccc2OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K17 compound treatment 0.266 0.016 0.86 0.8581 1.0 1513214 TimTec1_003405 CC(Oc1ccccc1)C(=O)Nc2cc(C)cc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K18 compound treatment 0.289 0.039 2.09 2.094 1.0 1270183 TimTec1_003406 CC(Oc1ccccc1)C(=O)NCCc2ccc(cc2)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K19 compound treatment 0.281 0.031 1.66 1.6641 1.0 3084799 TimTec1_003407 CCC(C)C(=O)Nc1nccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K20 compound treatment 0.26 0.00997 0.54 0.5356 1.0 1161699 TimTec1_003408 Cc1ccc(cc1)C2SCC(N2C(=O)c3cccc(Cl)c3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K21 compound treatment 0.294 0.044 2.36 2.3627 1.0 1190170 TimTec1_003409 CCN(Cc1ccccc1)C(=O)C(C)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K22 compound treatment 0.297 0.047 2.52 2.5239 1.0 3210685 TimTec1_003410 CC1(CC(=NC(=N1)SCC(=O)O)n2c3ccccc3c4ccccc24)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K23 mock treatment 0.258 0.00797 0.43 0.4282 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 K24 mock treatment 0.257 0.00697 0.37 0.3744 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L01 compound treatment 0.5 0.25 13.43 13.4327 1.0 3084803 TimTec1_003411 CC(C)Cc1ccc(/C=C/C(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L02 compound treatment 0.203 -0.047 -2.53 -2.5274 -1.0 3210686 TimTec1_003412 OC(=O)C1CC(=O)N(CCC2(CC3CC4CC(C3)C2)C4)/C(=N\c5ccc(Cl)cc5)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L03 compound treatment 0.285 0.035 1.88 1.8791 1.0 3084804 TimTec1_003413 COC(=O)c1ccn(COc2ccccc2Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L04 compound treatment 0.258 0.00797 0.43 0.4282 1.0 1272311 TimTec1_003414 COc1ccc(NC(=O)C2(CCCCC2)N(Cc3ccccc3)C(=O)Cc4nc(N)n[nH]4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L05 compound treatment 0.28 0.03 1.61 1.6104 1.0 1572389 TimTec1_003415 COC(=O)c1ccc(cc1)N2C(SC(C)C2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L06 compound treatment 0.333 0.083 4.46 4.4585 1.0 3210687 TimTec1_003416 Fc1ccc(NC(=O)c2cccc(OC(=S)Nc3cccc(Br)c3)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L07 compound treatment 0.492 0.242 13.0 13.0028 1.0 3084807 TimTec1_003417 CCOc1ccc(cc1)n2c(SCc3ccccc3)nnc2c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L08 compound treatment 0.211 -0.039 -2.1 -2.0975 -1.0 3210688 TimTec1_003418 CC(C)(C)Cc1ccc(OCCCC(=O)O)c(CC(C)(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L09 compound treatment 0.266 0.016 0.86 0.8581 1.0 3210689 TimTec1_003419 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)S(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L10 compound treatment 0.27 0.02 1.07 1.073 1.0 3084809 TimTec1_003420 CCN/C(=N\CC)/SC1CC(=O)N(CCc2ccccc2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L11 compound treatment 0.252 0.00197 0.11 0.1057 1.0 3210690 TimTec1_003421 CCC(N/C(=N/c1ccccc1C(=O)OC)/O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L12 compound treatment 0.285 0.035 1.88 1.8791 1.0 3084811 TimTec1_003422 N#Cc1ccc(nc1SCCOc2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L13 compound treatment 0.454 0.204 10.96 10.9608 1.0 1139626 TimTec1_003423 CC(Oc1ccc(Cl)c(C)c1)c2nc(no2)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L14 compound treatment 0.266 0.016 0.86 0.8581 1.0 3084813 TimTec1_003424 CC(C)CSc1nc(NC(=O)C)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L15 compound treatment 0.366 0.116 6.23 6.2319 1.0 3210691 TimTec1_003425 CC1=NC2=NN=C(NC(=O)Nc3ccc(Cl)c(Cl)c3)C2C(=C1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L16 compound treatment 0.298 0.048 2.58 2.5777 1.0 3084815 TimTec1_003426 OC1(CCCCC1)C(=O)/C=C/c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L17 compound treatment 0.334 0.084 4.51 4.5123 1.0 3210692 TimTec1_003427 CCOC(=O)c1ccc(NC(=S)NCCOC2(CC3CC4CC(C3)C2)C4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L18 compound treatment 0.286 0.036 1.93 1.9328 1.0 1179986 TimTec1_003428 CCOC(=O)CSc1nc2ccccc2n1C(=O)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L19 compound treatment 0.356 0.106 5.69 5.6945 1.0 3084845 TimTec1_003429 Oc1cc(n[nH]1)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L20 compound treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 3210693 TimTec1_003430 CCC(=O)NC(c1c(C)nn(c1O)c2ccccc2)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L21 compound treatment 0.301 0.051 2.74 2.7389 1.0 1146641 TimTec1_003431 CC1(C)CC(CCNC(=O)c2ccccc2C(=O)O)(Cc3ccccc3)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L22 compound treatment 0.269 0.019 1.02 1.0193 1.0 1486235 TimTec1_003432 CCCC1C(c2ccccc2)C3(C#N)C(=O)NC1(O)CC3(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L23 mock treatment 0.251 9.68E-4 0.05 0.052 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 L24 mock treatment 0.235 -0.015 -0.81 -0.8078 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M01 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 1722217 TimTec1_003433 CCCN(CCC)C(=O)c1cc(OC)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M02 compound treatment 0.266 0.016 0.86 0.8581 1.0 1254098 TimTec1_003434 O=C(CN1C(=O)c2ccccc2C1=O)N3CCN(Cc4ccccc4)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M03 compound treatment 0.261 0.011 0.59 0.5894 1.0 3084849 TimTec1_003435 CC1CC(C)CN(C1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M04 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 1397116 TimTec1_003436 CCc1ccccc1NC(=O)C(C)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M05 compound treatment 0.315 0.065 3.49 3.4912 1.0 3084851 TimTec1_003437 CC(C)NC(=O)c1ccc(cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M06 compound treatment 0.258 0.00797 0.43 0.4282 1.0 3210694 TimTec1_003438 CCCC(C)NC(=O)Cc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M07 compound treatment 0.238 -0.012 -0.65 -0.6466 -1.0 1130565 TimTec1_003439 COc1ccc(CC(=O)N2CCCCCC2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M08 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 3084854 TimTec1_003440 CC(C)CCNC(=O)Cc1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M09 compound treatment 0.266 0.016 0.86 0.8581 1.0 1411902 TimTec1_003441 CC1CC(C)CN(C1)C(=O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M10 compound treatment 0.256 0.00597 0.32 0.3207 1.0 1680018 TimTec1_003442 COc1cc(SC)ccc1C(=O)N(C)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M11 compound treatment 0.262 0.012 0.64 0.6431 1.0 1446751 TimTec1_003443 CCOc1ccccc1C(=O)NC2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M12 compound treatment 0.409 0.159 8.54 8.5426 1.0 1204191 TimTec1_003444 CC1CC(C)CN(C1)C(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M13 compound treatment 0.287 0.037 1.99 1.9866 1.0 1194660 TimTec1_003445 NS(=O)(=O)c1ccc(CNC(=O)c2ccccc2Oc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M14 compound treatment 0.236 -0.014 -0.75 -0.7541 -1.0 3084858 TimTec1_003446 COCC(C)NC(=O)c1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M15 compound treatment 0.249 -0.00103 -0.06 -0.0555 -1.0 1365776 TimTec1_003447 CN(C)S(=O)(=O)N1CCN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M16 compound treatment 0.36 0.11 5.91 5.9094 1.0 1365264 TimTec1_003448 CCOc1ccccc1C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M17 compound treatment 0.268 0.018 0.97 0.9655 1.0 3084861 TimTec1_003449 CCC(C)C(=O)Nc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M18 compound treatment 0.253 0.00297 0.16 0.1595 1.0 1138474 TimTec1_003450 CCC(CC)NC(=O)C(C)Oc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M19 compound treatment 0.279 0.029 1.56 1.5567 1.0 1334117 TimTec1_003451 CN(C)S(=O)(=O)N1CCC(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M20 compound treatment 0.26 0.00997 0.54 0.5356 1.0 1691322 TimTec1_003452 Cc1c(sc2nc[nH]c(=O)c12)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M21 compound treatment 0.257 0.00697 0.37 0.3744 1.0 1214562 TimTec1_003453 CCOc1ccc(NS(=O)(=O)N(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M22 compound treatment 0.303 0.053 2.85 2.8464 1.0 3084924 TimTec1_003454 OCc1occ(O)c(=O)c1C(Nc2ccccn2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M23 mock treatment 0.254 0.00397 0.21 0.2132 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 M24 mock treatment 0.252 0.00197 0.11 0.1057 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N01 compound treatment 0.24 -0.01 -0.54 -0.5391 -1.0 1273050 TimTec1_003455 Nc1ccccc1C(=O)c2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N02 compound treatment 0.299 0.049 2.63 2.6314 1.0 1558367 TimTec1_003456 O=c1[nH]c(=S)c2CCCc2n1Cc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N03 compound treatment 0.281 0.031 1.66 1.6641 1.0 3210695 TimTec1_003457 CCOC(=O)CC(=O)c1ccn(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N04 compound treatment 0.527 0.277 14.88 14.8837 1.0 1599603 TimTec1_003458 O=C1N(CCc2cn3cccnc3n2)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N05 compound treatment 0.328 0.078 4.19 4.1898 1.0 3084928 TimTec1_003459 Cc1cc(N/C=N/c2ccc(Br)c(C)c2)ccc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N06 compound treatment 0.258 0.00797 0.43 0.4282 1.0 3210696 TimTec1_003460 O=C1CCC(=O)N1[C@H]2CC(=O)[C@@H]3OCC2O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N07 compound treatment 0.499 0.249 13.38 13.379 1.0 3084930 TimTec1_003461 C/C(=C\c1ccco1)/C=N/n2c(S)nnc2COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N08 compound treatment 0.291 0.041 2.2 2.2015 1.0 3210697 TimTec1_003462 CC(C)c1ccc2c(c1)c3CCCc4cncn2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N09 compound treatment 0.44 0.19 10.21 10.2085 1.0 3210698 TimTec1_003463 CCc1nnc(SCC(=O)Nc2cc(C)on2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N10 compound treatment 0.442 0.192 10.32 10.3159 1.0 3084933 TimTec1_003464 Brc1ccc(cc1)C(=O)CSc2ncnn2CC(=O)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N11 compound treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 3210816 TimTec1_003465 CCC(=O)NC(Nc1c(C)n(C)n(c2ccccc2)c1=O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N12 compound treatment 0.337 0.087 4.67 4.6735 1.0 1413545 TimTec1_003466 O=C(NC(Cc1ccccc1)C(=O)Nc2nc(cs2)c3ccccc3)Oc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N13 compound treatment 0.293 0.043 2.31 2.309 1.0 1677156 TimTec1_003467 Cc1ccccc1C(=O)c2ccc3n(C)c(=O)n(C)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N14 compound treatment 0.27 0.02 1.07 1.073 1.0 3210817 TimTec1_003468 COc1ccc(CN/C(=N\c2ccccc2)/SC3CC(=O)N(C)C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N15 compound treatment 0.268 0.018 0.97 0.9655 1.0 3084935 TimTec1_003469 CC1(CCCCC12)N=C(c3ccccc3)C42C=CC(=O)C=C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N16 compound treatment 0.265 0.015 0.8 0.8043 1.0 3084936 TimTec1_003470 CC(C)(C)n1nnc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N17 compound treatment 0.353 0.103 5.53 5.5333 1.0 3210818 TimTec1_003471 O=C(C1=NNC2C1C(=O)N(C2=O)c3ccccc3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N18 compound treatment 0.513 0.263 14.13 14.1313 1.0 1154895 TimTec1_003472 CCOc1ccc2nc(SCc3ccc4OCOc4c3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N19 compound treatment 0.255 0.00497 0.27 0.267 1.0 1179027 TimTec1_003473 CCOC(=O)C1C(=S)NC(=C(C#N)C21CCCCC2)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N20 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 1721930 TimTec1_003474 OC(c1nn(C2CC(=O)C3OCC2O3)c(=S)n1c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N21 compound treatment 0.418 0.168 9.03 9.0262 1.0 1317806 TimTec1_003475 O=c1cc(sc(=O)[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N22 compound treatment 0.292 0.042 2.26 2.2553 1.0 1416310 TimTec1_003476 CCOC(=O)CSc1nc2ccccc2n1C(=O)Nc3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N23 mock treatment 0.243 -0.00703 -0.38 -0.3779 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 N24 mock treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O01 compound treatment 0.288 0.038 2.04 2.0403 1.0 1395834 TimTec1_003477 COc1ccc(CNC(=O)c2ccc(C)c(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O02 compound treatment 0.286 0.036 1.93 1.9328 1.0 1184377 TimTec1_003478 CCN(C(=O)C(C)Oc1ccccc1)c2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O03 compound treatment 0.259 0.00897 0.48 0.4819 1.0 1539114 TimTec1_003479 O=C(NC(c1ccccc1)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O04 compound treatment 0.256 0.00597 0.32 0.3207 1.0 3210819 TimTec1_003480 CC1CCCCN1C(=O)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O05 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 3084942 TimTec1_003481 CC(=O)N(Cc1ccccc1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O06 compound treatment 0.295 0.045 2.42 2.4165 1.0 3210820 TimTec1_003482 CN(Cc1ccccc1)C(=O)CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O07 compound treatment 0.251 9.68E-4 0.05 0.052 1.0 1675811 TimTec1_003483 O=C(CC(c1ccccc1)c2ccccc2)NCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O08 compound treatment 0.315 0.065 3.49 3.4912 1.0 1696603 TimTec1_003484 NS(=O)(=O)c1ccc(NC(=O)C(Sc2ccccc2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O09 compound treatment 0.266 0.016 0.86 0.8581 1.0 1437606 TimTec1_003485 CN(Cc1ccccc1)C(=O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O10 compound treatment 0.448 0.198 10.64 10.6384 1.0 1671134 TimTec1_003486 COc1cc(SC)ccc1C(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O11 compound treatment 0.301 0.051 2.74 2.7389 1.0 1515374 TimTec1_003487 COc1ccc(cc1)C(=O)Nc2ccc(C)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O12 compound treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 1496160 TimTec1_003488 COC(=O)C1CCN(CC1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O13 compound treatment 0.25 -3.23E-5 0.0 -0.0017 -1.0 1544697 TimTec1_003489 CCCC(C)NC(=O)N1CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O14 compound treatment 0.281 0.031 1.66 1.6641 1.0 1536093 TimTec1_003490 COCC(C)NC(=O)c1cccc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O15 compound treatment 0.273 0.023 1.23 1.2342 1.0 1517922 TimTec1_003491 O=C(C(Sc1ccccc1)c2ccccc2)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O16 compound treatment 0.262 0.012 0.64 0.6431 1.0 3210821 TimTec1_003492 CCC(CC)NC(=O)Cc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O17 compound treatment 0.254 0.00397 0.21 0.2132 1.0 1289736 TimTec1_003493 CCC(C(=O)NCC1CCCO1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O18 compound treatment 0.278 0.028 1.5 1.5029 1.0 1234784 TimTec1_003494 COC(=O)C1CCN(CC1)C(=O)C(C)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O19 compound treatment 0.32 0.07 3.76 3.7599 1.0 1449934 TimTec1_003495 COc1cc(SC)ccc1C(=O)NC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O20 compound treatment 0.332 0.082 4.4 4.4048 1.0 3210822 TimTec1_003496 C/C(=N\c1ccc(cc1)C(=O)O)/c2cc3c(=O)n(C)c4ccccc4c3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O21 compound treatment 0.327 0.077 4.14 4.1361 1.0 1156038 TimTec1_003497 CCOc1ccc(NC(=O)C(C)Oc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O22 compound treatment 0.264 0.014 0.75 0.7506 1.0 3085019 TimTec1_003498 OCc1coc(O)c(CN2CCc3ccccc3C2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O23 mock treatment 0.267 0.017 0.91 0.9118 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 O24 mock treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P01 compound treatment 0.233 -0.017 -0.92 -0.9153 -1.0 3210823 TimTec1_003499 COC[C@@H]1N=C(C)OC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P02 compound treatment 0.262 0.012 0.64 0.6431 1.0 1133107 TimTec1_003500 CCN(CC)CCc1c(C)c2ccc(O)cc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P03 compound treatment 0.304 0.054 2.9 2.9001 1.0 3085021 TimTec1_003501 Cc1ccc(NC(=O)c2ccn(n2)C(=O)Nc3cccc(Cl)c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P04 compound treatment 0.268 0.018 0.97 0.9655 1.0 3210824 TimTec1_003502 Cc1nnc(c2ccccc2)c(=O)n1/N=C/c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P05 compound treatment 0.446 0.196 10.53 10.5309 1.0 3210825 TimTec1_003503 OC(c1nnc(SCc2ccc(Br)cc2)n1c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P06 compound treatment 0.289 0.039 2.09 2.094 1.0 3085024 TimTec1_003504 CC1CCC(C)C(C1)NC(=O)c2ccc(I)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P07 compound treatment 0.514 0.264 14.19 14.1851 1.0 3210826 TimTec1_003505 CCN(C(=O)C)c1nnc(CSc2nc3ccccc3s2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P08 compound treatment 0.301 0.051 2.74 2.7389 1.0 3085026 TimTec1_003506 Cc1nc2cc3ccccc3cc2c(=O)n1CCCNC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P09 compound treatment 0.239 -0.011 -0.59 -0.5929 -1.0 1712637 TimTec1_003507 COCc1cc(C)nc2sc3c4nc5ccccc5n4nnc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P10 compound treatment 0.245 -0.00503 -0.27 -0.2704 -1.0 1522827 TimTec1_003508 O=C(Cc1cccc2ccccc12)NN3C(=O)C4C5CC(C=C5)C4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P11 compound treatment 0.241 -0.00903 -0.49 -0.4854 -1.0 1560331 TimTec1_003509 CC1(C)OC(=O)N(CC2CCCO2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P12 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1246647 TimTec1_003510 O=C(Nc1nc(cs1)c2ccccc2)Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P13 compound treatment 0.279 0.029 1.56 1.5567 1.0 1591772 TimTec1_003511 Cc1nn2c3CC(C)(C)CC(=O)c3cnc2c1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P14 compound treatment 0.257 0.00697 0.37 0.3744 1.0 3210827 TimTec1_003512 CCOC(=O)C1(O)CC(=NN1C(=O)c2cccc(Cl)c2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P15 compound treatment 0.237 -0.013 -0.7 -0.7003 -1.0 1520262 TimTec1_003513 COC(=O)c1ccc(cc1)C2N(Cc3ccccc3)CCN2Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P16 compound treatment 0.282 0.032 1.72 1.7179 1.0 3085100 TimTec1_003514 OC1=C/C(=N\c2ccc(F)c(c2)C(F)(F)F)/c3ccccc3C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P17 compound treatment 0.259 0.00897 0.48 0.4819 1.0 1236032 TimTec1_003515 Fc1nc(F)c(F)c(SC(=S)N2CCOCC2)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P18 compound treatment 0.248 -0.00203 -0.11 -0.1092 -1.0 1437494 TimTec1_003516 CCC(C)c1ccc(NC(=O)C2CC=CCC2C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P19 compound treatment 0.293 0.043 2.31 2.309 1.0 1266457 TimTec1_003517 CC(=O)OC1CC(C)(C)N(OC(=O)c2ccc(cc2)n3cnnn3)C(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P20 compound treatment 0.228 -0.022 -1.18 -1.184 -1.0 3085103 TimTec1_003518 NC(=N)SCc1nc(N)nc(n1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P21 compound treatment 0.37 0.12 6.45 6.4468 1.0 3210828 TimTec1_003519 C(Sc1nnc(c2ccccc2)n1c3ccccc3)C4CCOCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P22 compound treatment 0.243 -0.00703 -0.38 -0.3779 -1.0 1431856 TimTec1_003520 CCC(C)(OC1CCCCO1)C#CCN2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P23 mock treatment 0.239 -0.011 -0.59 -0.5929 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2072 P24 mock treatment 0.247 -0.00303 -0.16 -0.1629 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A01 compound treatment 0.479 0.223 12.0 11.997 1.0 3210829 TimTec1_003521 CCC(Sc1nncn1C)C(=O)Nc2ccc(OC(F)(F)F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A02 compound treatment 0.24 -0.0158 -0.85 -0.8464 -1.0 1243143 TimTec1_003522 Cc1nc2ccccc2n1c3ccc(cc3)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A03 compound treatment 0.342 0.0862 4.63 4.6349 1.0 1268944 TimTec1_003523 CSc1nc2cc(Oc3ccc4ccccc4c3)c(Cl)cc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A04 compound treatment 0.485 0.229 12.32 12.3194 1.0 3085107 TimTec1_003524 O=C(Nc1ccc2ccccc2c1)/C(=C/c3ccco3)/c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A05 compound treatment 0.28 0.0243 1.3 1.3031 1.0 3210949 TimTec1_003525 O=C1OC2(CCCC2)OC(=O)C1=Cc3ccc(OCc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A06 compound treatment 0.328 0.0722 3.88 3.8826 1.0 3210950 TimTec1_003526 Clc1ccc(cc1)C(=O)/C=C/2\C(=O)Nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A07 compound treatment 0.466 0.21 11.3 11.2984 1.0 1188087 TimTec1_003527 COc1cc2CCN3C(C(C)C(=O)C4=C3CSCC4=O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A08 compound treatment 0.267 0.0113 0.6 0.6046 1.0 3210951 TimTec1_003528 S=C(N1CCCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A09 compound treatment 0.226 -0.0297 -1.6 -1.5987 -1.0 1606147 TimTec1_003529 Cc1oc(c(CN2CCOCC2)c1C(=O)O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A10 compound treatment 0.232 -0.0238 -1.28 -1.2763 -1.0 3085108 TimTec1_003530 Cc1ccc(C)c(c1)c2csc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A11 compound treatment 0.344 0.0882 4.74 4.7424 1.0 1212994 TimTec1_003531 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccc(Cl)cc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A12 compound treatment 0.257 0.00125 0.07 0.0672 1.0 1431522 TimTec1_003532 CCOC(=O)c1oc2ccc(OC)cc2c1CN3CCN(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A13 compound treatment 0.275 0.0193 1.03 1.0345 1.0 1733965 TimTec1_003533 CCC1(C)Oc2ccc(NC(=O)c3cc(F)c(F)cc3Cl)cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A14 compound treatment 0.24 -0.0158 -0.85 -0.8464 -1.0 1590249 TimTec1_003534 CC1CCC2C(C)(CO)C(O)CCC2(C)C31CCC(C)(CO)O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A15 compound treatment 0.269 0.0133 0.71 0.712 1.0 1408570 TimTec1_003535 OCCCN1C(=O)c2ccccc2C1(O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A16 compound treatment 0.282 0.0262 1.41 1.4106 1.0 1133958 TimTec1_003536 O=C(COC(=O)CSc1nnc([nH]1)c2ccccc2)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A17 compound treatment 0.263 0.00725 0.39 0.3896 1.0 3085112 TimTec1_003537 COC(=O)c1c(N)oc2c(c3cccc(c3)C(F)(F)F)c4c(C(=O)OC)c(N)oc4cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A18 compound treatment 0.426 0.17 9.15 9.1489 1.0 1479296 TimTec1_003538 CCc1cccc2c(CCNC(=O)COc3ccc(F)cc3F)c(C)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A19 compound treatment 0.301 0.0452 2.43 2.4316 1.0 1638558 TimTec1_003539 COC(=O)c1cc(nc2ccccc12)N3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A20 compound treatment 0.266 0.0103 0.55 0.5508 1.0 3085182 TimTec1_003540 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A21 compound treatment 0.276 0.0203 1.09 1.0882 1.0 1636785 TimTec1_003541 CC(C)C(=O)Nc1nc(OC(=O)N(c2ccccc2)c3ccccc3)c4nc[nH]c4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A22 compound treatment 0.304 0.0483 2.59 2.5929 1.0 1508388 TimTec1_003542 O=C(OCc1ccc2nonc2c1)c3c4CCCCc4nc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A23 mock treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 A24 mock treatment 0.279 0.0233 1.25 1.2494 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B01 compound treatment 0.257 0.00125 0.07 0.0672 1.0 3085184 TimTec1_003543 CC12CCC(=O)N2c3ccccc3C(=O)N1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B02 compound treatment 0.269 0.0133 0.71 0.712 1.0 1731017 TimTec1_003544 CCCCc1c(C)nc2c(OC)cccc2c1SCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B03 compound treatment 0.268 0.0123 0.66 0.6583 1.0 1552863 TimTec1_003545 Fc1ccc(Sc2c(F)c(F)nc(N3CCNCC3)c2F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B04 compound treatment 0.35 0.0943 5.06 5.0648 1.0 3210952 TimTec1_003546 COc1ccc2C(Nc3nc4ccc(OC(F)(F)F)cc4s3)OC(=O)c2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B05 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 3085186 TimTec1_003547 Fc1ccc(cc1)N2C(=O)/C(=C/N3CCCCC3)/SC2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B06 compound treatment 0.355 0.0993 5.33 5.3335 1.0 3210953 TimTec1_003548 COC(=O)c1ccc(CSc2nnc3n(N)cnn23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B07 compound treatment 0.263 0.00725 0.39 0.3896 1.0 3085188 TimTec1_003549 Cc1cc(nc(SCc2ccccc2)c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B08 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 1390724 TimTec1_003550 COC(c1cccs1)c2c(C)[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B09 compound treatment 0.27 0.0143 0.77 0.7658 1.0 3210954 TimTec1_003551 Oc1ccccc1c2nc(O)c3c4CCCCc4sc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B10 compound treatment 0.277 0.0213 1.14 1.1419 1.0 3085190 TimTec1_003552 Cc1ccc(/C=C\2/SC(=O)N(CC(=O)Nc3ccc(C)cc3)C2=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B11 compound treatment 0.272 0.0163 0.87 0.8732 1.0 3210955 TimTec1_003553 Cc1sc2nc(nc(O)c2c1C)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B12 compound treatment 0.266 0.0103 0.55 0.5508 1.0 1921968 TimTec1_003554 Cc1c(Cl)cccc1NC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B13 compound treatment 0.244 -0.0118 -0.63 -0.6314 -1.0 1218019 TimTec1_003555 CC(NC(=O)C1CCCN1S(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B14 compound treatment 0.273 0.0173 0.93 0.927 1.0 3085194 TimTec1_003556 CCOc1cc(/C=C\2/S\C(=N/C)\N(C)C2=O)ccc1OCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B15 compound treatment 0.265 0.00925 0.5 0.4971 1.0 1154943 TimTec1_003557 CC1C(=O)OC(c2ccc(Br)cc2)C(C)(C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B16 compound treatment 0.274 0.0182 0.98 0.9807 1.0 3085196 TimTec1_003558 Cc1ccc(SCC(=O)N[C@@H]2C[C@H]3CC[C@@H]2C3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B17 compound treatment 0.278 0.0222 1.2 1.1957 1.0 1526862 TimTec1_003559 Cc1cc(Cl)ccc1OCC(=O)Nc2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B18 compound treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 1571119 TimTec1_003560 OC(=O)CCC(=O)Nc1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B19 compound treatment 0.271 0.0153 0.82 0.8195 1.0 1209861 TimTec1_003561 Cc1ccc(cc1)N(CC(O)CN2C(=O)NC(C)(C)C2=O)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B20 compound treatment 0.455 0.199 10.71 10.7073 1.0 1692625 TimTec1_003562 Cc1ccc(cc1)C(=O)Nc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B21 compound treatment 0.344 0.0882 4.74 4.7424 1.0 3085199 TimTec1_003563 CC(C)Cc1ccc(cc1)c2cc(O)[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B22 compound treatment 0.277 0.0213 1.14 1.1419 1.0 1410378 TimTec1_003564 OC(=O)c1ccc(O)c(SCN2CCCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B23 mock treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 B24 mock treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C01 compound treatment 0.401 0.145 7.81 7.8054 1.0 3085266 TimTec1_003565 FC(F)(F)Oc1ccc(NC(=O)COC(=O)/C=C\c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C02 compound treatment 0.262 0.00625 0.34 0.3359 1.0 3085268 TimTec1_003566 C[C@H]1[C@@H]2CC(C)(C)CC[C@]2(CO)CCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C03 compound treatment 0.316 0.0602 3.24 3.2377 1.0 1199129 TimTec1_003567 CN1CCN(CC1)c2ccc(Nc3ccnc4cc(Cl)ccc34)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C04 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 3085270 TimTec1_003568 CC1=CC(c2ccc(F)cc2)C(CC1)(C(=O)O)C(=O)n3nc(C)cc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C05 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 3210956 TimTec1_003569 CC(=O)NC(N1CCCC1=O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C06 compound treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1250474 TimTec1_003570 OC(=O)Cc1csc2nc(cn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C07 compound treatment 0.521 0.265 14.25 14.254 1.0 1127712 TimTec1_003571 Nn1c(CSc2nc3ccccc3o2)nnc1CSc4nc5ccccc5o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C08 compound treatment 0.264 0.00825 0.44 0.4433 1.0 3085273 TimTec1_003572 O/N=C/c1ccc(cc1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C09 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 3210957 TimTec1_003573 CC(C)C1C(=NN(C1=S)c2ccccc2)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C10 compound treatment 0.268 0.0123 0.66 0.6583 1.0 1006805 TimTec1_003574 NC(C(O)c1ccccc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C11 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 1375728 TimTec1_003575 COCc1cc(C)nc2sc(C(O)c3ccccc3)c(NC(=O)c4ccco4)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C12 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 1319536 TimTec1_003576 C=CCn1c(nn(CCC#N)c1=S)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C13 compound treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 1138165 TimTec1_003577 O=C(NC1CC1)c2n[nH]c(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C14 compound treatment 0.268 0.0123 0.66 0.6583 1.0 1631186 TimTec1_003578 CSc1ncnc2n(CN3CCOCC3)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C15 compound treatment 0.446 0.19 10.22 10.2236 1.0 3085277 TimTec1_003579 CCN(CC)c1nc(OC)nc(C#N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C16 compound treatment 0.272 0.0163 0.87 0.8732 1.0 1237261 TimTec1_003580 C(Nc1nc(NC2CCCCC2)nc(n1)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C17 compound treatment 0.394 0.138 7.43 7.4293 1.0 1373918 TimTec1_003581 COc1ccc(cc1)C(=O)Nc2ccccc2C3(C)CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C18 compound treatment 0.3 0.0442 2.38 2.3779 1.0 1306307 TimTec1_003582 Cn1c(=S)n(CCSc2nc3ccccc3n2c4ccccc4)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C19 compound treatment 0.373 0.117 6.3 6.3008 1.0 3085281 TimTec1_003583 Cc1ccccc1n2c(n[nH]c2=S)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C20 compound treatment 0.313 0.0573 3.08 3.0765 1.0 1451733 TimTec1_003584 CCOC(=O)c1ccc(CNS(=O)(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C21 compound treatment 0.281 0.0253 1.36 1.3569 1.0 1387125 TimTec1_003585 COC(C)(OCCn1c2ccccc2c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C22 compound treatment 0.588 0.332 17.85 17.8544 1.0 1631435 TimTec1_003586 CCOC(=O)c1ccc(CNC(=O)c2ccc(cc2)S(=O)(=O)c3ccccc3)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C23 mock treatment 0.268 0.0123 0.66 0.6583 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 C24 mock treatment 0.262 0.00625 0.34 0.3359 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D01 compound treatment 0.276 0.0203 1.09 1.0882 1.0 3211082 TimTec1_003587 COc1nc(Nc2ccccc2)nc(OCC(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D02 compound treatment 0.261 0.00525 0.28 0.2821 1.0 3085284 TimTec1_003588 Cn1c(=O)[nH]c(=O)c2n(CCC/N=C\3/CCCCN3)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D03 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 1240788 TimTec1_003589 CCOc1cc(ccc1OC)C2N(CC3N2CCc4ccccc34)S(=O)(=O)c5ccc(C)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D04 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 2108247 TimTec1_003590 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N[C@@]1(C)Oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D05 compound treatment 0.282 0.0262 1.41 1.4106 1.0 1269248 TimTec1_003591 CCN(CC)C(=S)Oc1ccc(cc1)C(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D06 compound treatment 0.504 0.248 13.34 13.3404 1.0 3085357 TimTec1_003592 Cc1cc([nH]c(=O)c1C#N)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D07 compound treatment 0.508 0.252 13.56 13.5554 1.0 1389688 TimTec1_003593 COc1cccc(c1)c2nnc(SCc3ccc(C#N)cc3Cl)n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D08 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 3085358 TimTec1_003594 CCOC(=O)C1=CN(C=C(C1c2ccccc2F)C(=O)OCC)c3ccc(C)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D09 compound treatment 0.383 0.127 6.84 6.8381 1.0 1652064 TimTec1_003595 Fc1ccccc1CSc2nnc3c4ccccc4n(CC=C)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D10 compound treatment 0.258 0.00225 0.12 0.1209 1.0 3211083 TimTec1_003596 COc1ccc(/C=C/2\S/C(=N/c3ccc(cc3)N4CCOCC4)/N(C)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D11 compound treatment 0.475 0.219 11.78 11.782 1.0 1144490 TimTec1_003597 COc1ccc(cc1)c2cc(nc(SCC(=O)N3CCCCC3)c2C#N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D12 compound treatment 0.247 -0.00875 -0.47 -0.4702 -1.0 1614237 TimTec1_003598 CCc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D13 compound treatment 0.353 0.0973 5.23 5.226 1.0 1504270 TimTec1_003599 Clc1ccccc1COc2ccc(cc2)N3CC(CC3=O)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D14 compound treatment 0.274 0.0182 0.98 0.9807 1.0 3085361 TimTec1_003600 Cc1cc(ccc1/C=N/n2cnnc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D15 compound treatment 0.396 0.14 7.54 7.5367 1.0 1542891 TimTec1_003601 CN(c1ccc(Cl)cc1)S(=O)(=O)c2cccc(c2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D16 compound treatment 0.348 0.0922 4.96 4.9573 1.0 3085364 TimTec1_003602 Cc1ccc(/C=N\n2nnnc2N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D17 compound treatment 0.259 0.00325 0.17 0.1746 1.0 1515864 TimTec1_003603 COC(=O)N1CCC(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D18 compound treatment 0.282 0.0262 1.41 1.4106 1.0 3211084 TimTec1_003604 COc1ccccc1N/C(=N\O)/C(=N/O)/Nc2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D19 compound treatment 0.489 0.233 12.53 12.5344 1.0 1479338 TimTec1_003605 CC1=CCC(C(C1)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D20 compound treatment 0.258 0.00225 0.12 0.1209 1.0 1527622 TimTec1_003606 CN(C)Cc1c(O)ccc2c(=O)c(Oc3cc(C)cc(C)c3)coc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D21 compound treatment 0.423 0.167 8.99 8.9877 1.0 3211085 TimTec1_003607 Fc1ccc(cc1)C(=O)/C=C\2/NCC3N(CCc4ccccc34)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D22 compound treatment 0.236 -0.0198 -1.06 -1.0613 -1.0 1154370 TimTec1_003608 Cc1ccccc1NC(=O)C2CC(O)CN2C(=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D23 mock treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 D24 mock treatment 0.239 -0.0168 -0.9 -0.9001 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E01 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 1604889 TimTec1_003609 Cc1ccc(cc1C(=O)N2CCCCCC2)S(=O)(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E02 compound treatment 0.539 0.283 15.22 15.2213 1.0 1585521 TimTec1_003610 CCn1cc(C(=O)O)c(=O)c2cc(F)c(NN3C(SCC3=O)c4ccccc4Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E03 compound treatment 0.276 0.0203 1.09 1.0882 1.0 3085369 TimTec1_003611 CC(N1C(=CC(C)(C)NC1=S)C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E04 compound treatment 0.254 -0.00175 -0.09 -0.094 -1.0 2114263 TimTec1_003612 COc1cc2CCN(C)c3cc4cc(OC)c(OC)cc4c(c1OC)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E05 compound treatment 0.242 -0.0138 -0.74 -0.7389 -1.0 3085371 TimTec1_003613 CC1CCc2ccccc2N1C(=N)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E06 compound treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 3211086 TimTec1_003614 Cc1c(/C=N/c2ccc(cc2)N3CCOCC3)c4ccccc4n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E07 compound treatment 0.254 -0.00175 -0.09 -0.094 -1.0 3211087 TimTec1_003615 COc1ccc(cc1OC)C2=Nn3cnnc3SC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E08 compound treatment 0.265 0.00925 0.5 0.4971 1.0 3085373 TimTec1_003616 NS(=O)(=O)c1ccc(cc1)n2cccc2/C=N/n3cnnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E09 compound treatment 0.24 -0.0158 -0.85 -0.8464 -1.0 3211088 TimTec1_003617 Cc1nn2C(=O)NC(Nc2c1c3ccccc3)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E10 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 1518082 TimTec1_003618 CN(Cn1c(=O)oc2ccccc12)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E11 compound treatment 0.322 0.0663 3.56 3.5601 1.0 1594658 TimTec1_003619 COc1ccc(CCn2c3CCCc3c(=S)[nH]c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E12 compound treatment 0.332 0.0762 4.1 4.0975 1.0 3211089 TimTec1_003620 CCOC(=O)c1c(C)sc2c(C)c(C)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E13 compound treatment 0.308 0.0522 2.81 2.8078 1.0 3084338 TimTec1_003621 COCc1cc(C)nc2sc3c(O)nc(nc3c12)c4ccccc4O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E14 compound treatment 0.374 0.118 6.35 6.3545 1.0 1260196 TimTec1_003622 OC(COc1ccccc1)CSc2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E15 compound treatment 0.268 0.0123 0.66 0.6583 1.0 1328330 TimTec1_003623 CCOC(=O)CC(Nc1nc(nc(n1)N2CCOCC2)N3CCOCC3)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E16 compound treatment 0.315 0.0592 3.18 3.184 1.0 3084342 TimTec1_003624 CC(=O)OCN1CCN(COC(=O)C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E17 compound treatment 0.296 0.0403 2.16 2.163 1.0 1565142 TimTec1_003625 CN(C)S(=O)(=O)c1cc(C(=O)NCC2CCCO2)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E18 compound treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 1165026 TimTec1_003626 OC(=O)Cc1c([nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E19 compound treatment 0.302 0.0462 2.49 2.4854 1.0 3211090 TimTec1_003627 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)OC3CSCC3NC(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E20 compound treatment 0.257 0.00125 0.07 0.0672 1.0 1227495 TimTec1_003628 Fc1ccc(Oc2cc(C#N)c(C#N)cc2n3nnc4ccccc34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E21 compound treatment 0.275 0.0193 1.03 1.0345 1.0 1507098 TimTec1_003629 COc1ccccc1NC(=O)NC(C)(C)c2cccc(c2)C(=C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E22 compound treatment 0.374 0.118 6.35 6.3545 1.0 3084346 TimTec1_003630 CC1(C)Cc2ccccc2C(=N1)CSc3nc(cc(n3)C(F)(F)F)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E23 mock treatment 0.263 0.00725 0.39 0.3896 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 E24 mock treatment 0.271 0.0153 0.82 0.8195 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F01 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 1683155 TimTec1_003631 Cc1cc(C(=O)N2CCCC2C(=O)O)c(C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F02 compound treatment 0.52 0.264 14.2 14.2002 1.0 1413129 TimTec1_003632 Brc1ccccc1OCc2ccc(cc2)C(=O)Nc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F03 compound treatment 0.409 0.153 8.24 8.2353 1.0 3084349 TimTec1_003633 CC1CC(n2ncnc2N1C(=O)CSc3nc4ccccc4o3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F04 compound treatment 0.241 -0.0147 -0.79 -0.7926 -1.0 1033523 TimTec1_003634 Nc1ncnc2n(CCO)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F05 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 3209122 TimTec1_003635 O/N=C/1\CCCCc2c1[nH]c3ccc(cc23)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F06 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 1204260 TimTec1_003636 CC1(CC2(C)CC3(CN)C1)CC(CCN)(C2)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F07 compound treatment 0.339 0.0833 4.47 4.4737 1.0 3209123 TimTec1_003637 COc1ccc(cc1)c2cs/c(=N\c3cc(ccc3C)C(=O)O)/o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F08 compound treatment 0.327 0.0712 3.83 3.8288 1.0 3084352 TimTec1_003638 Clc1ccc(SCCC(=O)NCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F09 compound treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 1270422 TimTec1_003639 CN(C)CCC(C)(O)Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F10 compound treatment 0.277 0.0213 1.14 1.1419 1.0 3084354 TimTec1_003640 CCOC(=O)CN1C(=O)S/C(=C\c2ccc(o2)c3ccc(Cl)cc3Cl)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F11 compound treatment 0.338 0.0823 4.42 4.4199 1.0 1341261 TimTec1_003641 COc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(C#CC4(O)CCCCC4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F12 compound treatment 0.267 0.0113 0.6 0.6046 1.0 1151583 TimTec1_003642 O=C(N1CCN(CC1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F13 compound treatment 0.374 0.118 6.35 6.3545 1.0 3084357 TimTec1_003643 CC1(CC(=O)Nc2ccccc2)NN=C(S1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F14 compound treatment 0.408 0.152 8.18 8.1816 1.0 3209124 TimTec1_003644 Brc1cc(/C=C(/C#N)\c2ccccc2)oc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F15 compound treatment 0.266 0.0103 0.55 0.5508 1.0 3084359 TimTec1_003645 Oc1cc(nc(SCCOc2ccccc2F)n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F16 compound treatment 0.274 0.0182 0.98 0.9807 1.0 1917462 TimTec1_003646 Nc1cc(N)nc(SCc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F17 compound treatment 0.442 0.186 10.01 10.0087 1.0 3084427 TimTec1_003647 C/C(=C/1\C(CC(=CC1=O)c2ccc(C)o2)c3ccccc3)/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F18 compound treatment 0.581 0.325 17.48 17.4783 1.0 1100509 TimTec1_003648 CCOC(=O)CSc1sc(C(=O)OCC)c(N)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F19 compound treatment 0.258 0.00225 0.12 0.1209 1.0 1681303 TimTec1_003649 CCC(=O)Oc1cc2c(C)cc(=O)oc2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F20 compound treatment 0.432 0.176 9.47 9.4713 1.0 1277376 TimTec1_003650 Brc1ccccc1OCC(=O)Nc2ccc(cc2)C(=O)OC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F21 compound treatment 0.312 0.0563 3.02 3.0228 1.0 1591398 TimTec1_003651 O=c1[nH]c2ccccc2c(=O)n1CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F22 compound treatment 0.247 -0.00875 -0.47 -0.4702 -1.0 3209125 TimTec1_003652 COC(=O)Cn1nnc(c2nnn(COC(=O)C)c2c3ccccc3)c1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F23 mock treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 F24 mock treatment 0.238 -0.0177 -0.95 -0.9538 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G01 compound treatment 0.244 -0.0118 -0.63 -0.6314 -1.0 1145213 TimTec1_003653 O=C(N1CC(=O)N(OCc2ccccc2)C1c3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G02 compound treatment 0.271 0.0153 0.82 0.8195 1.0 3209126 TimTec1_003654 CCN(CC)c1ccc(O)c(/C=N/N2C(=O)/C(=C/c3ccco3)/N=C2c4ccccc4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G03 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1490785 TimTec1_003655 CC1(C)CC(CC(C)(C)N1O)NC(=O)c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G04 compound treatment 0.244 -0.0118 -0.63 -0.6314 -1.0 3209127 TimTec1_003656 CN(C)Cc1c(N)cc2ccccc2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G05 compound treatment 0.233 -0.0227 -1.22 -1.2225 -1.0 3084709 TimTec1_003657 FC(F)(F)C1(NC(=O)N2C(=CSC2=N1)C3CC3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G06 compound treatment 0.567 0.311 16.73 16.7259 1.0 3209128 TimTec1_003658 O=C1NC(=O)/C(=C\Nc2sc3CCCCc3c2C#N)/C(=O)N1Cc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G07 compound treatment 0.238 -0.0177 -0.95 -0.9538 -1.0 3084710 TimTec1_003659 CSC1=NC(C)(C)CC21C=CC(=O)C(=C2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G08 compound treatment 0.503 0.247 13.29 13.2867 1.0 3209129 TimTec1_003660 CN(C)c1ccc(/N=C\2/C(=C(C#N)C(=O)N(CCO)C2=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G09 compound treatment 0.273 0.0173 0.93 0.927 1.0 1338522 TimTec1_003661 N#CCCn1c(nc2ccccc12)c3cncs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G10 compound treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1169940 TimTec1_003662 O=S(=O)(Nc1ccncc1)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G11 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 1221383 TimTec1_003663 O=C1CC(C2COC1O2)n3c(=O)oc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G12 compound treatment 0.257 0.00125 0.07 0.0672 1.0 1480783 TimTec1_003664 COc1ccccc1OCC(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G13 compound treatment 0.265 0.00925 0.5 0.4971 1.0 1147932 TimTec1_003665 Cc1ccc(cc1)c2cc3cc(C)c(C#N)c(N4CCCCCC4)n3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G14 compound treatment 0.239 -0.0168 -0.9 -0.9001 -1.0 2105438 TimTec1_003666 CC1CC(=O)N(N(C)C)C(C#N)(C#N)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G15 compound treatment 0.257 0.00125 0.07 0.0672 1.0 3084711 TimTec1_003667 CC(NC1=C(C(=O)/C=C/c2ccccc2)C(=O)CC(C)(C)C1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G16 compound treatment 0.306 0.0503 2.7 2.7003 1.0 1284183 TimTec1_003668 CCOC(=O)N1CCN(CC1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G17 compound treatment 0.292 0.0362 1.95 1.948 1.0 3209130 TimTec1_003669 Nc1nc(CSc2nnc(c3cccnc3)n2CC=C)nc(n1)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G18 compound treatment 0.434 0.178 9.58 9.5788 1.0 1317072 TimTec1_003670 Cn1c(=S)n(CCSc2nc3ccccc3[nH]2)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G19 compound treatment 0.534 0.278 14.95 14.9526 1.0 3209131 TimTec1_003671 O=C1Nc2ccccc2Oc3cc(Sc4ccccc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G20 compound treatment 0.276 0.0203 1.09 1.0882 1.0 3084712 TimTec1_003672 CCn1c(C)nnc1SCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G21 compound treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 1214067 TimTec1_003673 COc1ccc(cc1)C2CC(O)CC(c3ccc(OC)cc3)C24C(=O)NC(=O)NC4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G22 compound treatment 0.285 0.0293 1.57 1.5718 1.0 3084713 TimTec1_003674 CC1(C)Cc2ccccc2C(=N1)CSc3nc(c4CCCCc4n3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G23 mock treatment 0.254 -0.00175 -0.09 -0.094 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 G24 mock treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H01 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 1713697 TimTec1_003675 Cc1oc(cc1C(=O)N2CCCC2C(=O)O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H02 compound treatment 0.282 0.0262 1.41 1.4106 1.0 3209132 TimTec1_003676 COc1ccc(cc1OC)c2cc(nc(SC3CC(O)C4OCC3O4)n2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H03 compound treatment 0.442 0.186 10.01 10.0087 1.0 3084714 TimTec1_003677 CCN1C(=O)/C(=C\c2ccc(cc2Cl)N(C)C)/OC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H04 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1418481 TimTec1_003678 CC(C)C1NC(=O)N(C1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H05 compound treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 3209133 TimTec1_003679 COC(=O)c1ccn(n1)C(=O)c2ccnn2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H06 compound treatment 0.258 0.00225 0.12 0.1209 1.0 1349643 TimTec1_003680 CCCNS(=O)(=O)c1nc2nc(C)cc(C)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H07 compound treatment 0.536 0.28 15.06 15.06 1.0 3209134 TimTec1_003681 Cc1cc(=O)oc2c3/C(=C/c4ccccc4)/C(=O)Oc3ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H08 compound treatment 0.351 0.0953 5.12 5.1185 1.0 3209135 TimTec1_003682 CSc1cccc(NC(=O)c2ccc(CN3CCOCC3)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H09 compound treatment 0.522 0.266 14.31 14.3077 1.0 1565759 TimTec1_003683 COc1ccccc1CNc2ccc3n(cnc3c2)c4ccccc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H10 compound treatment 0.339 0.0833 4.47 4.4737 1.0 3209136 TimTec1_003684 O=C1NC(=O)/C(=C/c2cn(Cc3ccccc3C#N)c4ccccc24)/N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H11 compound treatment 0.28 0.0243 1.3 1.3031 1.0 1298968 TimTec1_003685 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H12 compound treatment 0.247 -0.00875 -0.47 -0.4702 -1.0 1242991 TimTec1_003686 O=C(N1CCCC1)c2ccccc2NS(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H13 compound treatment 0.309 0.0532 2.86 2.8615 1.0 1005358 TimTec1_003687 O=C(CC(C#N)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H14 compound treatment 0.469 0.213 11.46 11.4596 1.0 3209137 TimTec1_003688 COC(=O)c1c(NC(=O)/C=C/c2ccccc2)sc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H15 compound treatment 0.246 -0.00975 -0.52 -0.5239 -1.0 1564252 TimTec1_003689 CCc1ccc(cc1)N2C(=O)c3ccccc3NC2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H16 compound treatment 0.265 0.00925 0.5 0.4971 1.0 1096919 TimTec1_003690 CN1C(=O)C(O)(CC(=O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H17 compound treatment 0.261 0.00525 0.28 0.2821 1.0 1339640 TimTec1_003691 Cc1cccc(C)c1NC(=O)C2(CCCCC2)N(Cc3ccco3)C(=O)Cc4nc(N)n[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H18 compound treatment 0.259 0.00325 0.17 0.1746 1.0 3084715 TimTec1_003692 Cc1ccc(cc1)C(=O)N/C(=C\c2cn(nc2c3ccccc3)c4ccccc4)/C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H19 compound treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 1493856 TimTec1_003693 Oc1cc(n[nH]1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H20 compound treatment 0.288 0.0323 1.73 1.733 1.0 3084716 TimTec1_003694 Cc1ccc(CSc2ncnn2Cc3ccc(C)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H21 compound treatment 0.319 0.0633 3.4 3.3989 1.0 1254494 TimTec1_003695 COc1ccc(cc1)c2csc(n2)N3CCCC3C(=O)OCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H22 compound treatment 0.502 0.246 13.23 13.233 1.0 1446415 TimTec1_003696 COc1ccc(Cn2cc(nn2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H23 mock treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 H24 mock treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I01 compound treatment 0.535 0.279 15.01 15.0063 1.0 1413623 TimTec1_003697 COC(=O)COc1ccc(CSc2nc3ccccc3c(=O)n2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I02 compound treatment 0.236 -0.0198 -1.06 -1.0613 -1.0 1057656 TimTec1_003698 Nc1ncnc2n(cnc12)C3OC(CO)C=C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I03 compound treatment 0.32 0.0643 3.45 3.4527 1.0 3084720 TimTec1_003699 Cc1ccc(Nc2nc(C)cc(C)n2)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I04 compound treatment 0.243 -0.0127 -0.69 -0.6852 -1.0 3209257 TimTec1_003700 Nc1cc(c2ccccc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I05 compound treatment 0.265 0.00925 0.5 0.4971 1.0 1406532 TimTec1_003701 Fc1ccccc1n2nnnc2SCC(=O)N3c4ccccc4Sc5ccc(Cl)cc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I06 compound treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 3084723 TimTec1_003702 CN1C(=O)C(=CNCc2ccc3OCOc3c2)C(=O)N(C)C1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I07 compound treatment 0.318 0.0623 3.35 3.3452 1.0 3209258 TimTec1_003703 COc1ccc(/C=c\2/[nH]\c(=C\C(=O)c3ccccc3)\c(=O)[nH]c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I08 compound treatment 0.404 0.148 7.97 7.9666 1.0 1466355 TimTec1_003704 COc1ccc(Cl)cc1C(=O)Nc2ccc(NC(=O)c3ccco3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I09 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 3209259 TimTec1_003705 OC(=O)C1CSC(N1C(=O)c2ccccc2F)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I10 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 1721830 TimTec1_003706 COC(=O)CC1=C(C)C(=O)CC2C(C)(C)CCC[C@@]21C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I11 compound treatment 0.335 0.0793 4.26 4.2587 1.0 3209260 TimTec1_003707 FC(F)(F)c1nnc(NC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I12 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 3084757 TimTec1_003708 CN(C)C(=O)Cn1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I13 compound treatment 0.391 0.135 7.27 7.2681 1.0 3084758 TimTec1_003709 O=C(CSc1nc2ccccc2o1)NCCOC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I14 compound treatment 0.246 -0.00975 -0.52 -0.5239 -1.0 1684184 TimTec1_003710 COc1ccc(cc1OC)C(O)c2nccn2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I15 compound treatment 0.37 0.114 6.14 6.1396 1.0 3209261 TimTec1_003711 CCCc1c(C#N)c(N)nc(SCCCN2CCN(CC2)c3cccc(Cl)c3)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I16 compound treatment 0.409 0.153 8.24 8.2353 1.0 3084761 TimTec1_003712 NC(=S)N1N=C(CC1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I17 compound treatment 0.385 0.129 6.95 6.9456 1.0 3209262 TimTec1_003713 O=C(Nc1ccccc1)/N=c\2/[nH]c(=O)c3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I18 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 1743320 TimTec1_003714 CC1CC(NCc2ccccc2)N(N1c3ccccc3)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I19 compound treatment 0.365 0.109 5.87 5.8709 1.0 3209263 TimTec1_003715 NC(=O)CC1=NC(=O)CS1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I20 compound treatment 0.573 0.317 17.05 17.0484 1.0 1279387 TimTec1_003716 CC(=O)Nc1cccc(c1O)c2cc(=O)c3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I21 compound treatment 0.297 0.0413 2.22 2.2167 1.0 3084764 TimTec1_003717 CC1(C)COC(=N1)/C=C(\N)/c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I22 compound treatment 0.467 0.211 11.35 11.3521 1.0 1589286 TimTec1_003718 Clc1ccc(cc1)S(=O)(=O)c2cccc(c2)S(=O)(=O)N3CCC(=O)C4CCCCC43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I23 mock treatment 0.25 -0.00575 -0.31 -0.309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 I24 mock treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J01 compound treatment 0.254 -0.00175 -0.09 -0.094 -1.0 1383518 TimTec1_003719 Cc1nc(Oc2ccc(Cl)cc2)c(C(=O)O)c(C)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J02 compound treatment 0.392 0.136 7.32 7.3218 1.0 1251766 TimTec1_003720 COc1ccc(OC)c(Nc2nc(cs2)c3c(C)nc4sccn34)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J03 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 3084768 TimTec1_003721 CCN/1C(=O)CS\C1=N/N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J04 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 3209264 TimTec1_003722 CC(C)CC1NC(=O)N(C1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J05 compound treatment 0.304 0.0483 2.59 2.5929 1.0 3084770 TimTec1_003723 FC(F)(F)C(=O)Nc1ccc2nn(nc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J06 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 3209265 TimTec1_003724 Oc1ccccc1N2CCCC2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J07 compound treatment 0.308 0.0522 2.81 2.8078 1.0 3084773 TimTec1_003725 Nc1cc(ccc1Sc2nc3ccccc3s2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J08 compound treatment 0.284 0.0283 1.52 1.5181 1.0 3209266 TimTec1_003726 O=C(CCSc1ccccc1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J09 compound treatment 0.269 0.0133 0.71 0.712 1.0 1504517 TimTec1_003727 COc1cc(ccc1O)C(=O)OC2CC3CCC(C2)N3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J10 compound treatment 0.343 0.0873 4.69 4.6886 1.0 3084774 TimTec1_003728 CCOC(=O)CN1C(=O)S/C(=C\c2ccccc2OCc3ccccc3F)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J11 compound treatment 0.316 0.0602 3.24 3.2377 1.0 1209465 TimTec1_003729 NC(=O)c1oc2ccccc2c1NC(=O)CSc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J12 compound treatment 0.512 0.256 13.77 13.7703 1.0 3084776 TimTec1_003730 CCOC(=O)C1=C(C)N/C(=C/c2ccccc2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J13 compound treatment 0.266 0.0103 0.55 0.5508 1.0 1488603 TimTec1_003731 CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J14 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 3084778 TimTec1_003732 CN(Cc1ccccc1)C(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J15 compound treatment 0.56 0.304 16.35 16.3498 1.0 1610985 TimTec1_003733 Cn1cnnc1c2cccc(NC(=O)C(c3ccccc3)c4ccccc4)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J16 compound treatment 0.4 0.144 7.75 7.7517 1.0 1385134 TimTec1_003734 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J17 compound treatment 0.271 0.0153 0.82 0.8195 1.0 1566664 TimTec1_003735 Nc1nonc1c2nc3ccccc3n2Cc4ccc(F)cc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J18 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 3209267 TimTec1_003736 O=C(NC1CCS(=O)(=O)C1)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J19 compound treatment 0.312 0.0563 3.02 3.0228 1.0 1711733 TimTec1_003737 Cn1c(S)nnc1COc2ccc(cc2)C(C)(C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J20 compound treatment 0.39 0.134 7.21 7.2143 1.0 1660155 TimTec1_003738 CC(Oc1ccc2c3CCCc3c(=O)oc2c1)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J21 compound treatment 0.318 0.0623 3.35 3.3452 1.0 1699825 TimTec1_003739 COc1cccc(c1)C(=O)NCC2(CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J22 compound treatment 0.282 0.0262 1.41 1.4106 1.0 1582857 TimTec1_003740 Oc1c(c2ccn(n2)c3ccccc3)c(=O)n(c4ccccc4)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J23 mock treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 J24 mock treatment 0.243 -0.0127 -0.69 -0.6852 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K01 compound treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 1297374 TimTec1_003741 OC(=O)c1ccc(CSc2nnnn2C3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K02 compound treatment 0.282 0.0262 1.41 1.4106 1.0 1280009 TimTec1_003742 Brc1ccccc1C(CC(=O)c2ccccc2)C3C(=O)NC(=O)NC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K03 compound treatment 0.243 -0.0127 -0.69 -0.6852 -1.0 3084823 TimTec1_003743 CCC(=C1C(=O)NC(=O)NC1=O)Nc2ccccc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K04 compound treatment 0.275 0.0193 1.03 1.0345 1.0 3209268 TimTec1_003744 Cc1ccc(cc1)c2cc(O)nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K05 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 3209269 TimTec1_003745 O=c1[nH]c(=S)c2CCCc2n1N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K06 compound treatment 0.243 -0.0127 -0.69 -0.6852 -1.0 1426461 TimTec1_003746 CS(=O)(=O)N(CCC#N)Cc1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K07 compound treatment 0.282 0.0262 1.41 1.4106 1.0 1414086 TimTec1_003747 COc1cccc(c1)C2N(C(=O)C(=C2C(=O)c3ccc(Cl)cc3)O)c4ccc(OCC(=O)O)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K08 compound treatment 0.238 -0.0177 -0.95 -0.9538 -1.0 1107242 TimTec1_003748 O=S(=O)(Nc1cccnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K09 compound treatment 0.331 0.0752 4.04 4.0438 1.0 1611751 TimTec1_003749 CCOC(=O)c1ccc(cc1)N2C(C(Oc3ccccc3)C2=O)c4ccc(OCC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K10 compound treatment 0.263 0.00725 0.39 0.3896 1.0 3084827 TimTec1_003750 Cc1c(N=C2c3ccccc3-c4ccccc24)c(=O)n(c5ccccc5)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K11 compound treatment 0.321 0.0653 3.51 3.5064 1.0 1139869 TimTec1_003751 CCOC(=O)C1=C(NC(=O)C(C#N)C21CCCCC2)SCC(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K12 compound treatment 0.272 0.0163 0.87 0.8732 1.0 3084829 TimTec1_003752 CC(NC(=O)Oc1c(Cl)cc(Cl)c2ccccc12)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K13 compound treatment 0.262 0.00625 0.34 0.3359 1.0 1248629 TimTec1_003753 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K14 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 1738055 TimTec1_003754 NS(=O)(=O)c1ccccc1C(=O)N2CCN(CC2)C(=O)c3ccccc3S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K15 compound treatment 0.412 0.156 8.4 8.3965 1.0 3211496 TimTec1_003755 Fc1ccc(NC(=O)CS(=O)(=O)c2ccc(cc2Cl)C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K16 compound treatment 0.3 0.0442 2.38 2.3779 1.0 3084832 TimTec1_003756 CCOC(=O)Nc1cccc2nsnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K17 compound treatment 0.453 0.197 10.6 10.5998 1.0 3211497 TimTec1_003757 CCCCC(CC)CSc1nc2cccnc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K18 compound treatment 0.306 0.0503 2.7 2.7003 1.0 3211498 TimTec1_003758 Clc1ccc(Cl)c(c1)S(=O)(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K19 compound treatment 0.277 0.0213 1.14 1.1419 1.0 3084834 TimTec1_003759 NC(=O)Oc1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K20 compound treatment 0.299 0.0432 2.32 2.3242 1.0 1510460 TimTec1_003760 Fc1ccc(CC2Sc3nc4ccccc4n3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K21 compound treatment 0.261 0.00525 0.28 0.2821 1.0 3084866 TimTec1_003761 Cc1ccc(cc1)C(F)(F)C(F)(F)c2ccccc2c3nn[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K22 compound treatment 0.268 0.0123 0.66 0.6583 1.0 3211499 TimTec1_003762 Cn1nnc(n1)N2C(C(=C(O)C2=O)C(=O)c3ccco3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K23 mock treatment 0.269 0.0133 0.71 0.712 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 K24 mock treatment 0.266 0.0103 0.55 0.5508 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L01 compound treatment 0.285 0.0293 1.57 1.5718 1.0 3211500 TimTec1_003763 O=C(N/C(=C/c1ccccc1)/C(=O)N2CCc3ccccc3C2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L02 compound treatment 0.274 0.0182 0.98 0.9807 1.0 1595878 TimTec1_003764 CC(C)c1ccc(cc1)S(=O)(=O)N2CCN(C(C)C2)S(=O)(=O)c3ccc(cc3)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L03 compound treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 1381352 TimTec1_003765 NC(=O)CCNC1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L04 compound treatment 0.271 0.0153 0.82 0.8195 1.0 3084870 TimTec1_003766 COc1ccc(C(OC(=O)C)C#N)c(OCc2ccccc2)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L05 compound treatment 0.399 0.143 7.7 7.698 1.0 3211501 TimTec1_003767 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccc(Cl)cc4)/Oc3ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L06 compound treatment 0.239 -0.0168 -0.9 -0.9001 -1.0 1452130 TimTec1_003768 CC1(C)CC(CC(C)(C)N1O)NS(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L07 compound treatment 0.448 0.192 10.33 10.3311 1.0 3211502 TimTec1_003769 CCn1c2nc(cn2c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L08 compound treatment 0.305 0.0493 2.65 2.6466 1.0 3084873 TimTec1_003770 O=C(CCSc1ccccc1)NC2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L09 compound treatment 0.261 0.00525 0.28 0.2821 1.0 1521475 TimTec1_003771 CCc1c(nnn1c2nonc2N)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L10 compound treatment 0.37 0.114 6.14 6.1396 1.0 3211503 TimTec1_003772 Cc1cc(ccc1/C=C(/C#N)\c2ccc(F)cc2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L11 compound treatment 0.298 0.0423 2.27 2.2704 1.0 1396173 TimTec1_003773 NC(=O)CSC1=C(C#N)C(C(=C(N)N1)C#N)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L12 compound treatment 0.415 0.159 8.56 8.5578 1.0 3211504 TimTec1_003774 COC(=O)C/1=C(C)NC(=O)\C1=C/c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L13 compound treatment 0.488 0.232 12.48 12.4806 1.0 3211505 TimTec1_003775 Cc1oc(cc1C(=O)Nc2cccc(/C=C\C(=O)O)c2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L14 compound treatment 0.259 0.00325 0.17 0.1746 1.0 3084877 TimTec1_003776 Clc1ccc(C(=O)NC2CC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L15 compound treatment 0.296 0.0403 2.16 2.163 1.0 1596451 TimTec1_003777 Cc1oc(cc1C(=O)NCc2ccc(o2)C(=O)O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L16 compound treatment 0.249 -0.00675 -0.36 -0.3627 -1.0 1551836 TimTec1_003778 CC1=C(C(C(=C(C)N1)C(=O)N)c2ccco2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L17 compound treatment 0.273 0.0173 0.93 0.927 1.0 1181188 TimTec1_003779 CSc1ccccc1C(=O)Nc2cccc(c2)C(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L18 compound treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 1050401 TimTec1_003780 OC(COc1ccccc1)CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L19 compound treatment 0.286 0.0302 1.63 1.6256 1.0 1378484 TimTec1_003781 Cc1ccc(OCC(=O)Nc2ccc(cc2)N3CCOCC3)c(c1)n4nc5ccccc5n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L20 compound treatment 0.272 0.0163 0.87 0.8732 1.0 1477400 TimTec1_003782 CC1CN(CC(C)O1)C(=O)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L21 compound treatment 0.298 0.0423 2.27 2.2704 1.0 1507564 TimTec1_003783 COC(=O)c1ccccc1NC(=O)CC2(C(=O)c3ccccc3C2=O)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L22 compound treatment 0.449 0.193 10.38 10.3849 1.0 1451160 TimTec1_003784 Cn1c(=O)c(C(CC(=O)c2cc3ccccc3oc2=O)Nc4ccccc4)c(O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L23 mock treatment 0.266 0.0103 0.55 0.5508 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 L24 mock treatment 0.25 -0.00575 -0.31 -0.309 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M01 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 1644138 TimTec1_003785 COC(=O)C1OC2(CCCC2)OC1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M02 compound treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1168609 TimTec1_003786 O=C(CC(C1C(=O)NC(=O)NC1=O)c2ccccc2)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M03 compound treatment 0.245 -0.0107 -0.58 -0.5777 -1.0 3084947 TimTec1_003787 CCOC1=NC(N=C2Sc3ccccc3N21)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M04 compound treatment 0.285 0.0293 1.57 1.5718 1.0 3211506 TimTec1_003788 Nc1nc2ccc(Cl)cc2c(c1CN3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M05 compound treatment 0.43 0.174 9.36 9.3638 1.0 1277239 TimTec1_003789 COc1cc(OC)cc(c1)C(=O)c2ccc(cc2)C(=O)NC3(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M06 compound treatment 0.257 0.00125 0.07 0.0672 1.0 3084948 TimTec1_003790 OC(=O)Cn1cc(C=C2C(=O)NC(=O)NC2=O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M07 compound treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1682965 TimTec1_003791 OC1=C(C(N(C1=O)c2ccccn2)c3ccccc3)C(=O)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M08 compound treatment 0.253 -0.00275 -0.15 -0.1478 -1.0 3084949 TimTec1_003792 Cc1sc(N)c(C#N)c1c2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M09 compound treatment 0.313 0.0573 3.08 3.0765 1.0 3211507 TimTec1_003793 CCN(Cc1ccccc1)S(=O)(=O)c2nc3nc(C)c(C)c(C)n3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M10 compound treatment 0.269 0.0133 0.71 0.712 1.0 3084950 TimTec1_003794 Cc1cc(C)nc(N/C(=N/Cc2ccccc2Cl)/N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M11 compound treatment 0.481 0.225 12.1 12.1045 1.0 1289426 TimTec1_003795 CCCOc1c(cnc2ccccc12)c3ccc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M12 compound treatment 0.405 0.149 8.02 8.0204 1.0 3084951 TimTec1_003796 OC1(CC(=NN1)/C=C/c2cccs2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M13 compound treatment 0.254 -0.00175 -0.09 -0.094 -1.0 1348823 TimTec1_003797 CCNC1(CCC1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M14 compound treatment 0.323 0.0673 3.61 3.6139 1.0 3211508 TimTec1_003798 CC1=NN(C(=O)CSc2nnc(o2)c3ccncc3)C(C)(O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M15 compound treatment 0.275 0.0193 1.03 1.0345 1.0 1588714 TimTec1_003799 CCOc1ccc(CC2C(=O)NC(=O)N(Cc3ccccc3)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M16 compound treatment 0.281 0.0253 1.36 1.3569 1.0 1383650 TimTec1_003800 O=C(Nc1ccc2NS(=O)(=O)c3cccc1c23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M17 compound treatment 0.268 0.0123 0.66 0.6583 1.0 3211509 TimTec1_003801 CCN(CC)C(=S)SC1CC(=O)N(C1=O)c2ccc(cc2)S(=O)(=O)NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M18 compound treatment 0.324 0.0683 3.67 3.6676 1.0 1533734 TimTec1_003802 CC1=C(C(=O)Nc2ccccc2)C3(CCCCC3)C(=C(N1)SCC(=O)Nc4nccs4)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M19 compound treatment 0.369 0.113 6.09 6.0858 1.0 3211595 TimTec1_003803 COc1ccc(cc1)C2=CC(SC(=N)N2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M20 compound treatment 0.257 0.00125 0.07 0.0672 1.0 1699056 TimTec1_003804 CN(C1CC(C)(C)N(C)C(C)(C)C1)C(=O)c2cc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M21 compound treatment 0.289 0.0333 1.79 1.7868 1.0 1491671 TimTec1_003805 Nc1nc(N)c2sc(NCC=C)c(C#N)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M22 compound treatment 0.403 0.147 7.91 7.9129 1.0 3211596 TimTec1_003806 Fc1ccc(/C=c\2/[nH]\c(=C\C(=O)c3ccccc3)\c(=O)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M23 mock treatment 0.265 0.00925 0.5 0.4971 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 M24 mock treatment 0.26 0.00425 0.23 0.2284 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N01 compound treatment 0.333 0.0772 4.15 4.1513 1.0 3084958 TimTec1_003807 COc1nc(NC2CC2)nc(Nc3ccc(OC(F)(F)F)cc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N02 compound treatment 0.348 0.0922 4.96 4.9573 1.0 1476683 TimTec1_003808 OC(=O)c1cc(ccc1O)S(=O)(=O)Nc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N03 compound treatment 0.33 0.0742 3.99 3.99 1.0 3084960 TimTec1_003809 CCOC(=O)/C(=c\1/s\c(=C\2/C=Cc3ccccc3N2CC)\c(=O)n1CC)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N04 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1006588 TimTec1_003810 N#CC(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N05 compound treatment 0.266 0.0103 0.55 0.5508 1.0 1698122 TimTec1_003811 CCSC1=C(C#N)C(C(=C(C)N1)C(=O)OC(C)(C)C)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N06 compound treatment 0.264 0.00825 0.44 0.4433 1.0 3084962 TimTec1_003812 CCc1ccc(cc1)C2C(=CNC=C2C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N07 compound treatment 0.246 -0.00975 -0.52 -0.5239 -1.0 1644445 TimTec1_003813 CCOC(=O)C1=C(C)N(CCO)C(=O)NC1c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N08 compound treatment 0.256 2.5E-4 0.01 0.0134 1.0 3084964 TimTec1_003814 Cc1cc(/C=N/n2cnnc2)c(C)n1c3ccc(cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N09 compound treatment 0.291 0.0352 1.89 1.8943 1.0 3211597 TimTec1_003815 Cc1nnc(SCC(=O)O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N10 compound treatment 0.532 0.276 14.85 14.8451 1.0 3211598 TimTec1_003816 Fc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(o3)N4CCCC4)/S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N11 compound treatment 0.345 0.0892 4.8 4.7961 1.0 1466268 TimTec1_003817 NC1=C(C#N)C(C(=C(N1)SCc2ccccc2)C#N)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N12 compound treatment 0.255 -7.5E-4 -0.04 -0.0403 -1.0 3085029 TimTec1_003818 CCOC(=O)N1CCN(CC1)C(=O)CN(C2CCCCC2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N13 compound treatment 0.448 0.192 10.33 10.3311 1.0 3211599 TimTec1_003819 Nc1nc(SCC(=O)c2ccc3ccccc3c2)c(C#N)c(c1C#N)c4cccc(F)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N14 compound treatment 0.513 0.257 13.82 13.8241 1.0 3085032 TimTec1_003820 Brc1ccc(cc1)C(=O)NCCSc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N15 compound treatment 0.257 0.00125 0.07 0.0672 1.0 1677707 TimTec1_003821 O=C(CC(C(=O)c1ccccc1)c2ccccc2)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N16 compound treatment 0.459 0.203 10.92 10.9222 1.0 3085034 TimTec1_003822 COc1ccccc1OCCSc2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N17 compound treatment 0.287 0.0313 1.68 1.6793 1.0 1302141 TimTec1_003823 Clc1ccc(NC(=O)c2cc(Br)ccc2OCC(=O)NC3CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N18 compound treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 1645048 TimTec1_003824 CC(C)N1CC2(CN(CC(C1)(C2O)c3ccccc3)C(C)C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N19 compound treatment 0.538 0.282 15.17 15.1675 1.0 3085037 TimTec1_003825 COc1ccc(cc1)C(=O)/C=C\2/NCC3N(CCc4ccccc34)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N20 compound treatment 0.45 0.194 10.44 10.4386 1.0 1574760 TimTec1_003826 COc1ccc(cc1)C2CC(=Nc3ccccc3N2)c4cc5ccccc5oc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N21 compound treatment 0.263 0.00725 0.39 0.3896 1.0 3085038 TimTec1_003827 CC(=C)C(=O)Nc1ccc(O)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N22 compound treatment 0.328 0.0722 3.88 3.8826 1.0 1563548 TimTec1_003828 CC1=Nc2ccccc2Sc3c1c(=O)n(c4ccccc4)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N23 mock treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 N24 mock treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O01 compound treatment 0.366 0.11 5.92 5.9246 1.0 3085040 TimTec1_003829 CN/1CCS\C1=C/C=C/2\SC(=S)N(C)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O02 compound treatment 0.25 -0.00575 -0.31 -0.309 -1.0 1348649 TimTec1_003830 Oc1c(c2ccon2)c(=O)n(c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O03 compound treatment 0.353 0.0973 5.23 5.226 1.0 3085042 TimTec1_003831 CCc1nnc(NC(=O)c2nc[nH]n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O04 compound treatment 0.556 0.3 16.13 16.1348 1.0 1580872 TimTec1_003832 CCOC(=O)C1=NN(C(CC1=O)c2ccccc2)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O05 compound treatment 0.506 0.25 13.45 13.4479 1.0 3085044 TimTec1_003833 O=C(c1ccco1)c2cn(nc2C(=O)c3nc4ccccc4s3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O06 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 3211600 TimTec1_003834 CCN1C(=O)C(=Cc2ccc(cc2OC)N3CCOCC3)C(=O)N(CC)C1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O07 compound treatment 0.248 -0.00775 -0.42 -0.4165 -1.0 1409512 TimTec1_003835 COCC1=NN(C(=O)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O08 compound treatment 0.328 0.0722 3.88 3.8826 1.0 3211601 TimTec1_003836 CCCc1ccc(cc1)c2c(C)sc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O09 compound treatment 0.273 0.0173 0.93 0.927 1.0 3085047 TimTec1_003837 CC(C)CSc1nc(C)c(C)c(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O10 compound treatment 0.267 0.0113 0.6 0.6046 1.0 1586721 TimTec1_003838 CCC1(CC)Cc2ccccc2C(=N1)CC(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O11 compound treatment 0.259 0.00325 0.17 0.1746 1.0 1726435 TimTec1_003839 Cn1c(=O)n(C)c2c(O)c([nH]c2c1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O12 compound treatment 0.252 -0.00375 -0.2 -0.2015 -1.0 1470820 TimTec1_003840 CCC(=O)Nc1ccc2c(C)cc(C)nc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O13 compound treatment 0.528 0.272 14.63 14.6301 1.0 1381475 TimTec1_003841 CCCCc1nc(OCC(=O)c2ccccc2)c(C#N)c3CC(C)(C)OCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O14 compound treatment 0.462 0.206 11.08 11.0834 1.0 1312823 TimTec1_003842 O=CNc1ncc(s1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O15 compound treatment 0.237 -0.0187 -1.01 -1.0076 -1.0 3211602 TimTec1_003843 FC(F)(F)c1n[nH]c(c1C2(CC3CC4CC(C3)C2)C4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O16 compound treatment 0.423 0.167 8.99 8.9877 1.0 3211603 TimTec1_003844 C/C(=N\N1C(=N)SC(CC1=O)C(=O)Nc2ccc(cc2)C(=O)O)/CCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O17 compound treatment 0.496 0.24 12.91 12.9105 1.0 3085116 TimTec1_003845 O=C(NC1=NC(=O)CS1)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O18 compound treatment 0.397 0.141 7.59 7.5905 1.0 1326791 TimTec1_003846 COc1ccc(Cl)cc1NC(=O)CN(c2ccccc2)S(=O)(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O19 compound treatment 0.309 0.0532 2.86 2.8615 1.0 1539349 TimTec1_003847 Cc1cccc2c(cc(=O)[nH]c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O20 compound treatment 0.347 0.0912 4.9 4.9036 1.0 3211604 TimTec1_003848 CC(C)(CO)NC(=O)CSc1ccc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O21 compound treatment 0.507 0.251 13.5 13.5016 1.0 1701681 TimTec1_003849 Brc1ccc(NCc2c[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O22 compound treatment 0.478 0.222 11.94 11.9433 1.0 3085119 TimTec1_003850 CN1Cc2cc(CN3C(=O)c4ccccc4C3=O)ccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O23 mock treatment 0.268 0.0123 0.66 0.6583 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 O24 mock treatment 0.262 0.00625 0.34 0.3359 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P01 compound treatment 0.569 0.313 16.83 16.8334 1.0 1431065 TimTec1_003851 COc1ccc(cc1)n2cnc3cc(NCc4ccccc4O)ccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P02 compound treatment 0.267 0.0113 0.6 0.6046 1.0 1424914 TimTec1_003852 N#CCOc1nc(nc(n1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P03 compound treatment 0.319 0.0633 3.4 3.3989 1.0 1128232 TimTec1_003853 S=C(NCC1COc2ccccc2O1)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P04 compound treatment 0.272 0.0163 0.87 0.8732 1.0 3085122 TimTec1_003854 O=C(Nc1nnn[nH]1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P05 compound treatment 0.266 0.0103 0.55 0.5508 1.0 3211605 TimTec1_003855 OC1(NC(=C(C#N)C(C1C(=O)c2cccs2)c3ccccc3Cl)SCC=C)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P06 compound treatment 0.27 0.0143 0.77 0.7658 1.0 1623934 TimTec1_003856 COC(=O)C1=C(C)NC2=C(C1c3cccs3)C(=O)CC(C2)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P07 compound treatment 0.273 0.0173 0.93 0.927 1.0 1244903 TimTec1_003857 Cc1ccc(cc1)N(CC(=O)c2ccccc2)CC(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P08 compound treatment 0.52 0.264 14.2 14.2002 1.0 3211823 TimTec1_003858 CC/N=C/1\S/C(=C/c2ccc(OCC(=O)O)c(Cl)c2)/C(=O)N1CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P09 compound treatment 0.422 0.166 8.93 8.9339 1.0 3085124 TimTec1_003859 O=C(CCn1c(=O)sc2ccccc12)n3c(=O)sc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P10 compound treatment 0.254 -0.00175 -0.09 -0.094 -1.0 1013674 TimTec1_003860 Clc1ccc(cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P11 compound treatment 0.257 0.00125 0.07 0.0672 1.0 1436854 TimTec1_003861 Cc1oc2CCCCc2c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P12 compound treatment 0.282 0.0262 1.41 1.4106 1.0 3211705 TimTec1_003862 CN(CC(=O)N1CCN(CC1)c2ccccc2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P13 compound treatment 0.32 0.0643 3.45 3.4527 1.0 1144432 TimTec1_003863 CSc1ccc(cc1)S(=O)(=O)Nc2c(C)cc(OCC(=O)N3CCOCC3)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P14 compound treatment 0.247 -0.00875 -0.47 -0.4702 -1.0 3211706 TimTec1_003864 OC(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P15 compound treatment 0.243 -0.0127 -0.69 -0.6852 -1.0 1154434 TimTec1_003865 CN(C)S(=O)(=O)Nc1cccc(N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P16 compound treatment 0.411 0.155 8.34 8.3428 1.0 3211707 TimTec1_003866 COc1ccc(OCCSc2nc3ccccc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P17 compound treatment 0.416 0.16 8.61 8.6115 1.0 1371642 TimTec1_003867 CC(Oc1ccccc1Br)C(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P18 compound treatment 0.257 0.00125 0.07 0.0672 1.0 3085128 TimTec1_003868 C=CCN(C(=O)C1CCC=CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P19 compound treatment 0.307 0.0512 2.75 2.7541 1.0 1394194 TimTec1_003869 COC(=O)c1c(NC(=O)C2CCCC2)sc3CCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P20 compound treatment 0.303 0.0473 2.54 2.5391 1.0 3085130 TimTec1_003870 CCC(C)(C)c1ccc(OC2CSC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P21 compound treatment 0.284 0.0283 1.52 1.5181 1.0 3211708 TimTec1_003871 CCc1ccc2OCC(C(F)(F)F)S(=O)(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P22 compound treatment 0.271 0.0153 0.82 0.8195 1.0 3085131 TimTec1_003872 Oc1ccc(cc1)C(Nc2cccnc2)Sc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P23 mock treatment 0.251 -0.00475 -0.26 -0.2553 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2073 P24 mock treatment 0.242 -0.0138 -0.74 -0.7389 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A01 compound treatment 0.217 -0.0381 -2.05 -2.0472 -1.0 1509421 TimTec1_003873 OC(C1CN2CCC1CC2)(c3cccs3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A02 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 3085133 TimTec1_003874 Brc1ccc(NCCC(=O)c2ccc3OCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A03 compound treatment 0.25 -0.0051 -0.27 -0.2739 -1.0 1626877 TimTec1_003875 CCOC(=O)c1cc(sc1NC(=O)CCN2CCN(CC)CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A04 compound treatment 0.257 0.0019 0.1 0.1023 1.0 3211709 TimTec1_003876 COC(C(=O)NCc1ccc(Cl)cc1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A05 compound treatment 0.3 0.0449 2.41 2.413 1.0 3085202 TimTec1_003877 Cc1ccc(Nc2c(O)[nH]c(=O)n2N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A06 compound treatment 0.233 -0.0221 -1.19 -1.1874 -1.0 1917644 TimTec1_003878 CC1=C(C(=O)OCc2ccccc2)C3(O)C(=O)c4ccccc4C3(O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A07 compound treatment 0.321 0.0659 3.54 3.5415 1.0 3211710 TimTec1_003879 C(N1CCN(CC1)c2ncnc3sc4CCCCCc4c23)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A08 compound treatment 0.222 -0.0331 -1.78 -1.7786 -1.0 1084987 TimTec1_003880 OC(=O)c1ccc2nc(O)c(O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A09 compound treatment 0.262 0.0069 0.37 0.371 1.0 3211711 TimTec1_003881 CC(C)c1ccc(NC(=O)NCC2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A10 compound treatment 0.274 0.0189 1.02 1.0158 1.0 1015637 TimTec1_003882 Clc1ccc(cc1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A11 compound treatment 0.243 -0.0121 -0.65 -0.6501 -1.0 3211712 TimTec1_003883 Cn1cc(/C(=N\O)/Cc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A12 compound treatment 0.238 -0.0171 -0.92 -0.9187 -1.0 3211713 TimTec1_003884 Cc1nn(Cc2cccc(c2)C(=O)Nc3cccc(C)c3C)c(C)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A13 compound treatment 0.293 0.0379 2.04 2.0368 1.0 1851015 TimTec1_003885 CCc1ccc(OC(=O)COc2ccc(Br)c(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A14 compound treatment 0.245 -0.0101 -0.54 -0.5426 -1.0 3211714 TimTec1_003886 CC1(C)Cc2ccccc2C(=N1)NC(Cc3c[nH]c4ccccc34)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A15 compound treatment 0.466 0.211 11.33 11.3335 1.0 1208534 TimTec1_003887 COC(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A16 compound treatment 0.467 0.212 11.39 11.3872 1.0 1464409 TimTec1_003888 COc1ccc(OC)c2c(C)cc(=O)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A17 compound treatment 0.302 0.0469 2.52 2.5205 1.0 1255944 TimTec1_003889 COC(=O)c1ccccc1NC(=O)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A18 compound treatment 0.487 0.232 12.46 12.462 1.0 3211715 TimTec1_003890 Cc1nnc(Sc2cc(C)nc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A19 compound treatment 0.244 -0.0111 -0.6 -0.5963 -1.0 3211716 TimTec1_003891 CCOc1ccc(CC(=O)NC2CC(C)(C)N(C)C(C)(C)C2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A20 compound treatment 0.252 -0.0031 -0.17 -0.1664 -1.0 225200 TimTec1_003892 Nc1ccn(C2CC(O)C(CO)O2)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A21 compound treatment 0.26 0.0049 0.26 0.2635 1.0 3211717 TimTec1_003893 CC(NC(=O)Cc1c[nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A22 compound treatment 0.324 0.0689 3.7 3.7027 1.0 3085213 TimTec1_003894 Brc1cc(N/C=C\2/C(=O)NC(=S)N(C2=O)c3ccccc3)ccc1N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A23 mock treatment 0.237 -0.0181 -0.97 -0.9725 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 A24 mock treatment 0.276 0.0209 1.12 1.1233 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B01 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 3211718 TimTec1_003895 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cc(Br)c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B02 compound treatment 0.25 -0.0051 -0.27 -0.2739 -1.0 3211719 TimTec1_003896 COC(=O)C1=NNC(C1c2ccccc2)C(=O)OC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B03 compound treatment 0.242 -0.0131 -0.7 -0.7038 -1.0 3085215 TimTec1_003897 CN1[C@H](CC(O)c2ccccc2)CCCC1CC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B04 compound treatment 0.257 0.0019 0.1 0.1023 1.0 3211720 TimTec1_003898 CCOC(=O)CNc1nnc(c2ccccc2)c(c1C#N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B05 compound treatment 0.352 0.0969 5.21 5.2074 1.0 3085217 TimTec1_003899 COc1c(N)cc(Oc2cccc(c2)C(F)(F)F)c3nc(C)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B06 compound treatment 0.244 -0.0111 -0.6 -0.5963 -1.0 1047737 TimTec1_003900 COC(=O)C1CN(C)CCC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B07 compound treatment 0.425 0.17 9.13 9.1302 1.0 3211721 TimTec1_003901 CC(C)(C)c1oc(cc1COCC(F)(F)F)C(=O)Nc2ccc3c(c2)oc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B08 compound treatment 0.308 0.0529 2.84 2.8429 1.0 3211722 TimTec1_003902 CC(C)NC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B09 compound treatment 0.274 0.0189 1.02 1.0158 1.0 1305957 TimTec1_003903 Clc1cccc(Cl)c1CN(Cc2ccccc2)c3ncnc4[nH]cnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B10 compound treatment 0.272 0.0169 0.91 0.9083 1.0 1515666 TimTec1_003904 NNC(=O)C1C2CCCCC12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B11 compound treatment 0.265 0.0099 0.53 0.5322 1.0 3211723 TimTec1_003905 OC(=O)C(=C1SCCS1)C(=O)/C=C/c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B12 compound treatment 0.423 0.168 9.02 9.0228 1.0 3085287 TimTec1_003906 Cc1ccc(cc1)N2C(=O)C(=CC2(O)c3ccccc3)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B13 compound treatment 0.261 0.0059 0.32 0.3172 1.0 1580685 TimTec1_003907 CCc1ccccc1NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B14 compound treatment 0.262 0.0069 0.37 0.371 1.0 3211724 TimTec1_003908 COc1ccccc1N/C(=N\O)/c2nonc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B15 compound treatment 0.364 0.109 5.85 5.8522 1.0 3085290 TimTec1_003909 Clc1ccc(cc1)c2ccc(/C=N/C3CCS(=O)(=O)C3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B16 compound treatment 0.252 -0.0031 -0.17 -0.1664 -1.0 3211725 TimTec1_003910 OC(=O)c1cccc(/N=C/c2ccc(cc2)N3CCOCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B17 compound treatment 0.49 0.235 12.62 12.6232 1.0 3211726 TimTec1_003911 CCn1c(=O)c(/C=C\2/C(=O)NN=C2c3ccccc3)c(O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B18 compound treatment 0.254 -0.0011 -0.06 -0.0589 -1.0 3085292 TimTec1_003912 C(=N/c1n[nH]c(\N=C\c2ccccc2)n1)\c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B19 compound treatment 0.436 0.181 9.72 9.7214 1.0 3211727 TimTec1_003913 FC(F)(F)c1nnc(S)n1/N=C/c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B20 compound treatment 0.282 0.0269 1.45 1.4457 1.0 3085294 TimTec1_003914 FC(F)(F)c1ccccc1NC(=O)CSc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B21 compound treatment 0.293 0.0379 2.04 2.0368 1.0 1454180 TimTec1_003915 Cc1nn(c(Cl)c1C2N(Cc3ccccc3)CCN2Cc4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B22 compound treatment 0.269 0.0139 0.75 0.7471 1.0 1565629 TimTec1_003916 CCOC(=O)c1c(CN(C)C)n(C)c2cc(Br)c(OC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B23 mock treatment 0.239 -0.0161 -0.87 -0.865 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 B24 mock treatment 0.233 -0.0221 -1.19 -1.1874 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C01 compound treatment 0.247 -0.0081 -0.44 -0.4351 -1.0 1262920 TimTec1_003917 CC(C)NC(=O)c1ccccc1CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C02 compound treatment 0.42 0.165 8.86 8.8616 1.0 3085297 TimTec1_003918 O=C(CCN1CCN(CC1)c2ccccc2)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C03 compound treatment 0.283 0.0279 1.5 1.4995 1.0 1344204 TimTec1_003919 COc1ccc(cc1)c2csc(NC(=O)Cc3cccc4ccccc34)c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C04 compound treatment 0.261 0.0059 0.32 0.3172 1.0 3211824 TimTec1_003920 CC(NC(=O)c1ccc(CSc2ccccc2)cc1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C05 compound treatment 0.315 0.0599 3.22 3.2191 1.0 3085300 TimTec1_003921 NC1=NNC2=C(NNN12)c3ccccc3C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C06 compound treatment 0.241 -0.0141 -0.76 -0.7575 -1.0 1738981 TimTec1_003922 O=c1n(nc(c2ccccc2)c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C07 compound treatment 0.339 0.0839 4.51 4.5088 1.0 3085302 TimTec1_003923 COc1cc(/C=C/C)ccc1Oc2nnc(C)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C08 compound treatment 0.492 0.237 12.73 12.7307 1.0 1410588 TimTec1_003924 Brc1cccc(NC(=O)c2ccc(OC3CSC3)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C09 compound treatment 0.253 -0.0021 -0.11 -0.1127 -1.0 1451839 TimTec1_003925 CC(C)c1ccc(CNC(=O)c2ccc(=O)[nH]c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C10 compound treatment 0.4 0.145 7.79 7.7868 1.0 3211825 TimTec1_003926 COc1ccc(c(OC)c1)c2oc3ccc(OC)cc3c(=O)c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C11 compound treatment 0.315 0.0599 3.22 3.2191 1.0 1232921 TimTec1_003927 Cc1ccc(OC(=O)COc2ccc3ccccc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C12 compound treatment 0.34 0.0849 4.56 4.5625 1.0 1881298 TimTec1_003928 CC(C)(C)c1ccccc1NC(=O)c2cccc(Cn3cc(Cl)cn3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C13 compound treatment 0.309 0.0539 2.9 2.8966 1.0 3085306 TimTec1_003929 CCc1ccc(OC(=O)c2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C14 compound treatment 0.457 0.202 10.85 10.8499 1.0 3211826 TimTec1_003930 NS(=O)(=O)c1ccc(Nc2nc(cs2)c3cccs3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C15 compound treatment 0.545 0.29 15.58 15.5788 1.0 1544060 TimTec1_003931 Brc1c(OCC(=O)NCCC2=CCCCC2)ccc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C16 compound treatment 0.303 0.0479 2.57 2.5742 1.0 1058123 TimTec1_003932 COc1ccc(OC)c2c(C)cc(Cl)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C17 compound treatment 0.277 0.0219 1.18 1.177 1.0 1506791 TimTec1_003933 CCC(CC)NC(=O)c1ccc(OC)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C18 compound treatment 0.257 0.0019 0.1 0.1023 1.0 1441088 TimTec1_003934 OC(=O)C(NC(=O)CSc1nnnn1c2ccccc2)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C19 compound treatment 0.253 -0.0021 -0.11 -0.1127 -1.0 3085378 TimTec1_003935 CN(C)c1nc(N)nc(Cn2ccnc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C20 compound treatment 0.28 0.0249 1.34 1.3382 1.0 3211827 TimTec1_003936 NNc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C21 compound treatment 0.268 0.0129 0.69 0.6934 1.0 1668209 TimTec1_003937 Nc1nnnn1CC(=O)N(Cc2ccco2)C3(CCCCC3)C(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C22 compound treatment 0.307 0.0519 2.79 2.7892 1.0 3211828 TimTec1_003938 COCCN1C(=C(C(=O)OC)/C(=C/c2c(Cl)cccc2Cl)/C1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C23 mock treatment 0.261 0.0059 0.32 0.3172 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 C24 mock treatment 0.258 0.0029 0.16 0.156 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D01 compound treatment 0.236 -0.0191 -1.03 -1.0262 -1.0 3085382 TimTec1_003939 CC(=O)OC[C@H]1O[C@H](C[C@@H]1OC(=O)C)n2cc(C)c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D02 compound treatment 0.28 0.0249 1.34 1.3382 1.0 3211829 TimTec1_003940 Fc1ccc(Nn2c(nc3ccccc3c2=O)c4ccccc4)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D03 compound treatment 0.488 0.233 12.52 12.5157 1.0 3085384 TimTec1_003941 CCN(CC)/C=C/C(=O)c1ccccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D04 compound treatment 0.281 0.0259 1.39 1.392 1.0 1632200 TimTec1_003942 CCOC(=O)c1sc(NC(=O)CC)c(C(=O)OCC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D05 compound treatment 0.315 0.0599 3.22 3.2191 1.0 3085386 TimTec1_003943 COc1cc2CC3(Cc2cc1OC)N(C)Cc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D06 compound treatment 0.246 -0.0091 -0.49 -0.4888 -1.0 3211830 TimTec1_003944 CNC(C)[C@@H](O)c1ccc(O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D07 compound treatment 0.287 0.0319 1.71 1.7144 1.0 1329060 TimTec1_003945 OCC1(CO)COC2(CCCCC2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D08 compound treatment 0.264 0.0089 0.48 0.4784 1.0 3211831 TimTec1_003946 CCOC(=O)c1sc(nc1C)n2nc(C)cc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D09 compound treatment 0.533 0.278 14.93 14.9339 1.0 3211832 TimTec1_003947 COc1ccc(cc1)N2CC(=O)N(/N=C/c3ccc(cc3)N(C)C)C2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D10 compound treatment 0.333 0.0779 4.19 4.1864 1.0 3085389 TimTec1_003948 O=C(CSc1cccc(n1)c2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D11 compound treatment 0.415 0.16 8.59 8.5929 1.0 3211833 TimTec1_003949 O=C/1Nc2ccccc2\C1=N/N3C(=O)/C(=C/c4ccccc4)/N=C3c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D12 compound treatment 0.538 0.283 15.2 15.2026 1.0 1282238 TimTec1_003950 CC(C)NC(=O)COc1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D13 compound treatment 0.348 0.0929 4.99 4.9924 1.0 1920102 TimTec1_003951 FC(F)(F)c1cccc(/N=C/2\C(=O)Nc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D14 compound treatment 0.253 -0.0021 -0.11 -0.1127 -1.0 3085391 TimTec1_003952 COC1=CC(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D15 compound treatment 0.268 0.0129 0.69 0.6934 1.0 3085393 TimTec1_003953 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)C)C2=O)/c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D16 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 1168752 TimTec1_003954 CCOC(=O)C1=C(C)OC(=C(C(=O)OCC)C21C(=O)Nc3ccccc32)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D17 compound treatment 0.487 0.232 12.46 12.462 1.0 1702369 TimTec1_003955 COc1ccc(cc1)c2csc(n2)N3N=C(C)C(C(C(C#N)C(=O)N)c4ccc(Cl)cc4)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D18 compound treatment 0.261 0.0059 0.32 0.3172 1.0 3085395 TimTec1_003956 CCOC(=O)c1sc2c(OC)c(Br)ccc2c1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D19 compound treatment 0.594 0.339 18.21 18.212 1.0 3085397 TimTec1_003957 CC1(C)CC(=O)C(=CNc2ncnc3[nH]cnc23)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D20 compound treatment 0.387 0.132 7.09 7.0882 1.0 1514121 TimTec1_003958 O=C(CCc1ccccc1)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D21 compound treatment 0.478 0.223 11.98 11.9784 1.0 3211834 TimTec1_003959 OCCNc1ccn(c2nc(sc2c3ccccc3)c4ccccc4)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D22 compound treatment 0.266 0.0109 0.59 0.5859 1.0 1914384 TimTec1_003960 Cc1ccc(CCSCC(=O)O)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D23 mock treatment 0.256 9.03E-4 0.05 0.0485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 D24 mock treatment 0.245 -0.0101 -0.54 -0.5426 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E01 compound treatment 0.249 -0.0061 -0.33 -0.3276 -1.0 1410817 TimTec1_003961 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCCCCC4)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E02 compound treatment 0.261 0.0059 0.32 0.3172 1.0 3085400 TimTec1_003962 CC(C)c1ccc(cc1)C2C(=C(C)Nc3nc4ccccc4n23)C(=O)Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E03 compound treatment 0.571 0.316 16.98 16.976 1.0 1389044 TimTec1_003963 Cc1ccc(o1)C(=O)Nc2sc3CCCCc3c2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E04 compound treatment 0.435 0.18 9.67 9.6676 1.0 3084361 TimTec1_003964 Brc1cccc(c1)c2n[nH]c(=S)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E05 compound treatment 0.346 0.0909 4.88 4.8849 1.0 3211835 TimTec1_003965 O=C(NCCOc1ccccc1)c2ccc(=O)[nH]c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E06 compound treatment 0.285 0.0299 1.61 1.6069 1.0 3084365 TimTec1_003966 S=C(NCc1ccccc1)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E07 compound treatment 0.254 -0.0011 -0.06 -0.0589 -1.0 1680390 TimTec1_003967 CN1CCN(CC1)c2ncnc3sc(C)c(c4ccccc4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E08 compound treatment 0.243 -0.0121 -0.65 -0.6501 -1.0 1123501 TimTec1_003968 COC(C(=O)NCc1ccc(OC)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E09 compound treatment 0.292 0.0369 1.98 1.9831 1.0 3211836 TimTec1_003969 Clc1ccc(NC(=O)N(Cc2ccccc2)Cc3ccccc3)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E10 compound treatment 0.259 0.0039 0.21 0.2098 1.0 1804050 TimTec1_003970 CC(SCc1ccccc1)C(=O)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E11 compound treatment 0.258 0.0029 0.16 0.156 1.0 1707898 TimTec1_003971 Cc1ccc(o1)C(O)c2nccn2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E12 compound treatment 0.265 0.0099 0.53 0.5322 1.0 3211977 TimTec1_003972 CCc1c(C)sc(NC(=O)CCCC(=O)O)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E13 compound treatment 0.417 0.162 8.7 8.7003 1.0 1707943 TimTec1_003973 CCOc1ccc(NC(=O)CCC(=O)n2nc(cc2c3ccccc3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E14 compound treatment 0.314 0.0589 3.17 3.1653 1.0 3211915 TimTec1_003974 Cc1ccc(Nc2nc(Nc3ccc(C)cc3)nc(Sc4nnc[nH]4)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E15 compound treatment 0.527 0.272 14.61 14.6115 1.0 1558319 TimTec1_003975 Brc1c(OCC(=O)NC2CCCCC2)ccc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E16 compound treatment 0.27 0.0149 0.8 0.8009 1.0 3084371 TimTec1_003976 O=S(=O)(Nc1cccc(c1)C2OCCCO2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E17 compound treatment 0.268 0.0129 0.69 0.6934 1.0 1490598 TimTec1_003977 Brc1ccccc1NC(=O)c2ccccc2Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E18 compound treatment 0.304 0.0489 2.63 2.628 1.0 1419531 TimTec1_003978 CC1(C)CC(CCO1)n2c(NCCO)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E19 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 3084373 TimTec1_003979 O=C(NC(Cc1ccccc1)C(=O)N2CCCCC2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E20 compound treatment 0.26 0.0049 0.26 0.2635 1.0 3211916 TimTec1_003980 CC1CN(C2CC(O)C(CO)O2)C(=O)NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E21 compound treatment 0.28 0.0249 1.34 1.3382 1.0 1203573 TimTec1_003981 O=C1CC2CS(=O)(=O)CC2N1c3ccc(Oc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E22 compound treatment 0.272 0.0169 0.91 0.9083 1.0 3211917 TimTec1_003982 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccncc2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E23 mock treatment 0.257 0.0019 0.1 0.1023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 E24 mock treatment 0.264 0.0089 0.48 0.4784 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F01 compound treatment 0.241 -0.0141 -0.76 -0.7575 -1.0 1780915 TimTec1_003983 OCC1OC(Nc2ccc(cc2)C(=O)O)C(O)C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F02 compound treatment 0.341 0.0859 4.62 4.6163 1.0 3211918 TimTec1_003984 CN1CCN(CC1)c2nsc(NO)c2Nc3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F03 compound treatment 0.452 0.197 10.58 10.5812 1.0 1313296 TimTec1_003985 Oc1ccccc1C(=O)c2cnn(c2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F04 compound treatment 0.329 0.0739 3.97 3.9714 1.0 3211919 TimTec1_003986 COc1cc(/C=C\2/SC(=S)N(NC(=O)C)C2=O)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F05 compound treatment 0.414 0.159 8.54 8.5391 1.0 3211920 TimTec1_003987 CN(C)c1ccc2N=c3cc(C)c(N)cc3=Sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F06 compound treatment 0.47 0.215 11.55 11.5485 1.0 3084378 TimTec1_003988 COc1cc(O)c(C(=O)Cc2ccc(Cl)cc2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F07 compound treatment 0.272 0.0169 0.91 0.9083 1.0 3211921 TimTec1_003989 CCOC(=O)NC(=S)N1CCN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F08 compound treatment 0.526 0.271 14.56 14.5578 1.0 3084380 TimTec1_003990 Cc1cc(c(C#N)c(SCC(=O)c2ccccc2)n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F09 compound treatment 0.405 0.15 8.06 8.0555 1.0 3211922 TimTec1_003991 Fc1ccc(/C=N/N2C(=O)CN(C2=S)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F10 compound treatment 0.439 0.184 9.88 9.8826 1.0 3084382 TimTec1_003992 Cc1cc(C(=O)Nc2ccccc2)c(o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F11 compound treatment 0.301 0.0459 2.47 2.4667 1.0 3084969 TimTec1_003993 CCN(CC)C1=N/C(=C/c2ccccc2)/C(=O)N1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F12 compound treatment 0.398 0.143 7.68 7.6793 1.0 3211923 TimTec1_003994 Brc1ccc(cc1)C(=O)NCCOc2ccccc2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F13 compound treatment 0.321 0.0659 3.54 3.5415 1.0 3084971 TimTec1_003995 Oc1cc(O)c2sc3nc(cc(c3c2n1)C(F)(F)F)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F14 compound treatment 0.314 0.0589 3.17 3.1653 1.0 1360453 TimTec1_003996 Cc1ccc(CCC2C3=C(CCCC3=O)OC4=C2C(=O)CCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F15 compound treatment 0.314 0.0589 3.17 3.1653 1.0 3084973 TimTec1_003997 CSc1oc(nc1S(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F16 compound treatment 0.259 0.0039 0.21 0.2098 1.0 1588811 TimTec1_003998 CNC(=O)CCC(=O)Nc1cc(Cl)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F17 compound treatment 0.342 0.0869 4.67 4.67 1.0 3211924 TimTec1_003999 CCOc1ccc(cc1)C(C)(C)C(=O)NN2C(=O)/C(=C/c3ccccn3)/N=C2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F18 compound treatment 0.514 0.259 13.91 13.9129 1.0 3084976 TimTec1_004000 COc1ccc(/C=N/c2nc3ccc(Br)cc3s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F19 compound treatment 0.241 -0.0141 -0.76 -0.7575 -1.0 1627471 TimTec1_004001 O=S(=O)(NCc1ccncc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F20 compound treatment 0.26 0.0049 0.26 0.2635 1.0 1030019 TimTec1_004002 CN(C)C(=O)c1ccccc1C(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F21 compound treatment 0.48 0.225 12.09 12.0858 1.0 3084978 TimTec1_004003 N#Cc1nc(oc1NCCCN2CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F22 compound treatment 0.283 0.0279 1.5 1.4995 1.0 1252023 TimTec1_004004 Cc1cccc(NC(=O)C2C3CCC=CCCC23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F23 mock treatment 0.256 9.03E-4 0.05 0.0485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 F24 mock treatment 0.227 -0.0281 -1.51 -1.5099 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G01 compound treatment 0.263 0.0079 0.42 0.4247 1.0 1401883 TimTec1_004005 Cc1c(C)c2ccccc2n1CC(O)CNCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G02 compound treatment 0.489 0.234 12.57 12.5695 1.0 3084981 TimTec1_004006 O=C1OCc2cc(ccc12)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G03 compound treatment 0.317 0.0619 3.33 3.3265 1.0 3211925 TimTec1_004007 Cc1sc2ncnc(N3CCN(CC3)c4cccc(c4)C(F)(F)F)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G04 compound treatment 0.452 0.197 10.58 10.5812 1.0 1527185 TimTec1_004008 COc1ccccc1c2cc(=O)c3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G05 compound treatment 0.308 0.0529 2.84 2.8429 1.0 1639456 TimTec1_004009 Oc1ccccc1C(Nc2ccccn2)c3ccc4cccnc4c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G06 compound treatment 0.414 0.159 8.54 8.5391 1.0 1650064 TimTec1_004010 Oc1ccccc1C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G07 compound treatment 0.25 -0.0051 -0.27 -0.2739 -1.0 1085927 TimTec1_004011 CC1CCCCN1C(=O)Nc2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G08 compound treatment 0.436 0.181 9.72 9.7214 1.0 3085053 TimTec1_004012 O=C(N[C@@H]1C[C@H]2CC[C@@H]1C2)c3ccc(CSc4ccccc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G09 compound treatment 0.348 0.0929 4.99 4.9924 1.0 1516181 TimTec1_004013 C1CN(CC1c2ccccc2)c3nc(cs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G10 compound treatment 0.424 0.169 9.08 9.0765 1.0 3211926 TimTec1_004014 OC(=O)c1ccccc1NC(=O)CCSc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G11 compound treatment 0.56 0.305 16.38 16.3849 1.0 1741292 TimTec1_004015 CCCOC(=O)c1ccc(NC(=O)c2ccc(C)c(Br)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G12 compound treatment 0.279 0.0239 1.28 1.2845 1.0 3211927 TimTec1_004016 C1CN(CCO1)c2ccc(/N=C/c3ccc(Sc4nc5ccccc5[nH]4)o3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G13 compound treatment 0.335 0.0799 4.29 4.2938 1.0 1267880 TimTec1_004017 COC(=O)c1c(NC(=O)c2ccccc2)sc3CCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G14 compound treatment 0.258 0.0029 0.16 0.156 1.0 3211928 TimTec1_004018 OC(=O)/C(=C\c1ccco1)/NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G15 compound treatment 0.42 0.165 8.86 8.8616 1.0 1175724 TimTec1_004019 Cc1ccc(NC(=O)c2ccco2)cc1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G16 compound treatment 0.424 0.169 9.08 9.0765 1.0 3211929 TimTec1_004020 Cc1ccc(NCC(=O)SCc2csc(Nc3ccccc3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G17 compound treatment 0.613 0.358 19.23 19.233 1.0 3085059 TimTec1_004021 COc1ccccc1c2nnc(o2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G18 compound treatment 0.32 0.0649 3.49 3.4878 1.0 3211930 TimTec1_004022 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G19 compound treatment 0.255 -9.68E-5 -0.01 -0.0052 -1.0 3211931 TimTec1_004023 CC(C)CSCC1OC(C(O)C1O)n2cnc3c(N)ncnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G20 compound treatment 0.244 -0.0111 -0.6 -0.5963 -1.0 907315 TimTec1_004024 CCc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G21 compound treatment 0.425 0.17 9.13 9.1302 1.0 1121708 TimTec1_004025 COc1cccc(NC(=O)COc2ccccc2OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G22 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 1216245 TimTec1_004026 Fc1ccc(cc1)S(=O)(=O)N(CC(=O)NCC2CCCO2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G23 mock treatment 0.265 0.0099 0.53 0.5322 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 G24 mock treatment 0.245 -0.0101 -0.54 -0.5426 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H01 compound treatment 0.259 0.0039 0.21 0.2098 1.0 1279518 TimTec1_004027 Nc1cnn(C2OC(COC(=O)c3ccccc3)C(O)C2O)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H02 compound treatment 0.553 0.298 16.01 16.0087 1.0 3211932 TimTec1_004028 Cc1ccc(C)c(NS(=O)(=O)c2ccc(NC(=N)Nc3nncc(C)n3)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H03 compound treatment 0.273 0.0179 0.96 0.9621 1.0 1187682 TimTec1_004029 COc1ccc(cc1)c2cc(CC(C)C)nc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H04 compound treatment 0.26 0.0049 0.26 0.2635 1.0 1408114 TimTec1_004030 CCc1ccccc1NC(=O)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H05 compound treatment 0.346 0.0909 4.88 4.8849 1.0 3211978 TimTec1_004031 CN(C)c1ccc(CCNC(=O)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H06 compound treatment 0.468 0.213 11.44 11.441 1.0 3085065 TimTec1_004032 COc1cccc(c1)c2cc(=O)c3ccc(O)cc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H07 compound treatment 0.295 0.0399 2.14 2.1443 1.0 3211979 TimTec1_004033 C1CN(CCO1)/C(=N\c2ccccc2)/Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H08 compound treatment 0.268 0.0129 0.69 0.6934 1.0 3211980 TimTec1_004034 FC(F)(F)c1cc(nc(SCC(=O)c2ccccc2)c1C#N)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H09 compound treatment 0.263 0.0079 0.42 0.4247 1.0 3085068 TimTec1_004035 CC(=O)Nc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H10 compound treatment 0.433 0.178 9.56 9.5601 1.0 3211981 TimTec1_004036 Cc1cc(nc2sc(C(=O)Nc3ccc(cc3)C(=O)N)c(N)c12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H11 compound treatment 0.478 0.223 11.98 11.9784 1.0 3085069 TimTec1_004037 OCC1OC(Oc2cccc(O)c2CCCc3ccc(O)cc3)C(O)C(O)C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H12 compound treatment 0.26 0.0049 0.26 0.2635 1.0 1309367 TimTec1_004038 O=C(N1CCOCC1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H13 compound treatment 0.311 0.0559 3.0 3.0041 1.0 1455904 TimTec1_004039 CCc1nc2sc(C#N)c(N)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H14 compound treatment 0.292 0.0369 1.98 1.9831 1.0 1365090 TimTec1_004040 NC(=O)c1ccc(cc1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H15 compound treatment 0.337 0.0819 4.4 4.4013 1.0 1421754 TimTec1_004041 COc1ccc(NCn2c3ccccc3c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H16 compound treatment 0.273 0.0179 0.96 0.9621 1.0 1486169 TimTec1_004042 Cc1ccc2N3CCN(C(CCCC(=O)c2c1)C3=O)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H17 compound treatment 0.536 0.281 15.1 15.0952 1.0 3211982 TimTec1_004043 Cc1ccc(cc1)C2=NNC3(S2)C(=O)Nc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H18 compound treatment 0.275 0.0199 1.07 1.0696 1.0 3085139 TimTec1_004044 Cc1ccc2nc(/N=C/c3ccc(Cl)cc3Cl)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H19 compound treatment 0.257 0.0019 0.1 0.1023 1.0 3211983 TimTec1_004045 CCn1nc(C)c(/N=C/c2ccc(N(C)C)c(Br)c2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H20 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 1009941 TimTec1_004046 CC(=O)OC(C(=O)c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H21 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 1132941 TimTec1_004047 CC1(C)CC(CC(C)(C)N1)N2CCC(O)(C(C2)C(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H22 compound treatment 0.531 0.276 14.83 14.8265 1.0 3085143 TimTec1_004048 Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Br)cc2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H23 mock treatment 0.252 -0.0031 -0.17 -0.1664 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 H24 mock treatment 0.246 -0.0091 -0.49 -0.4888 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I01 compound treatment 0.239 -0.0161 -0.87 -0.865 -1.0 1679534 TimTec1_004049 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I02 compound treatment 0.272 0.0169 0.91 0.9083 1.0 3085145 TimTec1_004050 CN(C)c1nc(N)nc(COc2ccc(C)c(C)c2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I03 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 1257756 TimTec1_004051 O=c1ccc2ccc(Oc3nc(nc4ccccc34)c5cccnc5)cc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I04 compound treatment 0.244 -0.0111 -0.6 -0.5963 -1.0 1524978 TimTec1_004052 CCS(=O)(=O)N(CC(=O)N1CCCC1)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I05 compound treatment 0.347 0.0919 4.94 4.9387 1.0 3211984 TimTec1_004053 FC(F)(F)c1cccc(Nc2ncnc3sc4CCCc4c23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I06 compound treatment 0.265 0.0099 0.53 0.5322 1.0 1023730 TimTec1_004054 NC(=N)SCc1ccc(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I07 compound treatment 0.262 0.0069 0.37 0.371 1.0 3211985 TimTec1_004055 CC1CCCC(C)N1C(=O)Nc2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I08 compound treatment 0.376 0.121 6.5 6.4971 1.0 3085148 TimTec1_004056 CCN(CC)c1ccc(/C=C/C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I09 compound treatment 0.253 -0.0021 -0.11 -0.1127 -1.0 3211986 TimTec1_004057 Cn1c(NC(=O)c2cc(F)c(F)cc2Cl)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I10 compound treatment 0.244 -0.0111 -0.6 -0.5963 -1.0 1379820 TimTec1_004058 CCOC(=O)CC(N)c1cccc(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I11 compound treatment 0.253 -0.0021 -0.11 -0.1127 -1.0 3211987 TimTec1_004059 Cc1ccc(CCC(=O)O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I12 compound treatment 0.485 0.23 12.35 12.3545 1.0 3085152 TimTec1_004060 COc1ccc(/N=C/c2cccn2c3ccc(Br)cc3)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I13 compound treatment 0.485 0.23 12.35 12.3545 1.0 3211988 TimTec1_004061 NS(=O)(=O)c1ccc(NC(=O)/C=C/c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I14 compound treatment 0.521 0.266 14.29 14.2891 1.0 1519495 TimTec1_004062 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)CSc4nnc[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I15 compound treatment 0.468 0.213 11.44 11.441 1.0 1570543 TimTec1_004063 CCOc1ccc(NCC(=O)n2nc(C)cc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I16 compound treatment 0.558 0.303 16.28 16.2774 1.0 3211989 TimTec1_004064 Cc1ccc(SCCNC(=O)c2ccc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I17 compound treatment 0.262 0.0069 0.37 0.371 1.0 1040036 TimTec1_004065 OCC1OC(C(O)C1O)n2cnc3cncnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I18 compound treatment 0.493 0.238 12.78 12.7844 1.0 3085155 TimTec1_004066 S=C(NCc1ccco1)Nc2ccc3nc(c4ccccn4)c(nc3c2)c5ccccn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I19 compound treatment 0.263 0.0079 0.42 0.4247 1.0 3211990 TimTec1_004067 OC(Cc1c[nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I20 compound treatment 0.259 0.0039 0.21 0.2098 1.0 3551456 TimTec1_004068 CN(C)c1ncnc2n(cnc12)C3OC(CO)C(N)C3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I21 compound treatment 0.306 0.0509 2.74 2.7354 1.0 1678356 TimTec1_004069 COc1ccc(cc1OC)c2n[nH]c(=S)n2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I22 compound treatment 0.299 0.0439 2.36 2.3593 1.0 1862685 TimTec1_004070 Fc1cccc(NC(=O)c2cccc(c2)c3cc4ccccc4oc3=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I23 mock treatment 0.254 -0.0011 -0.06 -0.0589 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 I24 mock treatment 0.257 0.0019 0.1 0.1023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J01 compound treatment 0.246 -0.0091 -0.49 -0.4888 -1.0 1494538 TimTec1_004071 OC1C(COC(=O)c2ccccc2)OC3C1Oc4nc(=O)ccn34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J02 compound treatment 0.298 0.0429 2.31 2.3055 1.0 3085226 TimTec1_004072 Cc1cc(/C=N/c2ccc(cc2)N3CCOCC3)c(C)n1c4ccc(cc4C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J03 compound treatment 0.264 0.0089 0.48 0.4784 1.0 3211991 TimTec1_004073 COC(OC)C1(C)NC(=O)c2ccccc2N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J04 compound treatment 0.567 0.312 16.76 16.761 1.0 3211992 TimTec1_004074 CC1=CCC2C(C)(C)[C@@H](O)CCC2(C)C1COc3ccc4ccc(=O)oc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J05 compound treatment 0.611 0.356 19.13 19.1255 1.0 3085228 TimTec1_004075 O=C(COc1ccc2ccccc2c1)Nc3ccc(Cc4ccccn4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J06 compound treatment 0.249 -0.0061 -0.33 -0.3276 -1.0 3211993 TimTec1_004076 C[C@H](CSC(=O)C)C(=O)N1CCC[C@H]1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J07 compound treatment 0.273 0.0179 0.96 0.9621 1.0 3085230 TimTec1_004077 OCC1(CO)COC(=N1)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J08 compound treatment 0.354 0.0989 5.31 5.3149 1.0 3211994 TimTec1_004078 Cc1cc(C)c(C#N)c(SCC(=O)C2CC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J09 compound treatment 0.273 0.0179 0.96 0.9621 1.0 1375364 TimTec1_004079 O=C1CC(Nc2ccc(cc2)N3CCOCC3)C(=O)N1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J10 compound treatment 0.297 0.0419 2.25 2.2518 1.0 1019637 TimTec1_004080 CN(C)c1nc2cc(Cl)ccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J11 compound treatment 0.56 0.305 16.38 16.3849 1.0 3211995 TimTec1_004081 Oc1ccc(cc1)C(=O)NN2C(SCC2=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J12 compound treatment 0.336 0.0809 4.35 4.3476 1.0 3211996 TimTec1_004082 COc1ccc(/C=C/2\C(=O)N(C(c3ccc(F)cc3)S2(=O)=O)c4ccc(Cl)cc4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J13 compound treatment 0.592 0.337 18.1 18.1045 1.0 1535419 TimTec1_004083 OC(COc1ccc(cc1)C(=O)c2ccccc2)CN3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J14 compound treatment 0.257 0.0019 0.1 0.1023 1.0 1646040 TimTec1_004084 CCOC(=O)C1=C(C)NC(=O)NC1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J15 compound treatment 0.354 0.0989 5.31 5.3149 1.0 1413879 TimTec1_004085 Ic1ccc2nc(c3ccccc3)n(NC(=S)NCC=C)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J16 compound treatment 0.446 0.191 10.26 10.2587 1.0 1498022 TimTec1_004086 O=C1C2C(C(C=CC2c3ccccc3)c4ccccc4)C(=O)N1Cc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J17 compound treatment 0.324 0.0689 3.7 3.7027 1.0 1546528 TimTec1_004087 CCC(=O)N(C(=O)CC)c1cc2oc3ccccc3c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J18 compound treatment 0.524 0.269 14.45 14.4503 1.0 3211997 TimTec1_004088 COc1ccc(/C=N/c2nc3c(ccc4ccccc34)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J19 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 3085236 TimTec1_004089 OCc1coc(O)c(CN2CCCCC2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J20 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 1049537 TimTec1_004090 OCCNC(=O)c1ccc(cc1)C(=O)NCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J21 compound treatment 0.512 0.257 13.81 13.8054 1.0 3085238 TimTec1_004091 O=c1[nH]cnc2ccc(NC(=S)NC3CC3)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J22 compound treatment 0.29 0.0349 1.88 1.8756 1.0 1129244 TimTec1_004092 Brc1ccc2[nH]c3C(CCCc3c2c1)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J23 mock treatment 0.249 -0.0061 -0.33 -0.3276 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 J24 mock treatment 0.25 -0.0051 -0.27 -0.2739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K01 compound treatment 0.26 0.0049 0.26 0.2635 1.0 3085240 TimTec1_004093 Cc1ccc(Cl)c(c1)C(=O)NC2=CC(=O)CC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K02 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 3212056 TimTec1_004094 COC(OC)C1Nc2ccccc2C(=O)N1c3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K03 compound treatment 0.36 0.105 5.64 5.6373 1.0 1870332 TimTec1_004095 COc1ccc(cc1)c2cc(c3ccccc3O)n(n2)C4C(=O)Nc5ccc(Br)cc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K04 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 3085242 TimTec1_004096 CC(C)(C)NC(=S)NCc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K05 compound treatment 0.26 0.0049 0.26 0.2635 1.0 1547474 TimTec1_004097 CN1CCN(CC1)C(c2ccncc2)c3ccc4cccnc4c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K06 compound treatment 0.285 0.0299 1.61 1.6069 1.0 1031437 TimTec1_004098 COc1cc(CC=C)ccc1OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K07 compound treatment 0.279 0.0239 1.28 1.2845 1.0 3212057 TimTec1_004099 FC(F)(F)c1cccc(NC(=O)N2CCN(Cc3ccccc3)CC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K08 compound treatment 0.387 0.132 7.09 7.0882 1.0 3085313 TimTec1_004100 O=C1CC(N(N=C1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K09 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 1194194 TimTec1_004101 O=C(CCC(=O)Nc1cccc2ccccc12)Nc3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K10 compound treatment 0.261 0.0059 0.32 0.3172 1.0 3085314 TimTec1_004102 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2C1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K11 compound treatment 0.524 0.269 14.45 14.4503 1.0 3212058 TimTec1_004103 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)[C@@H]4CCCC[C@@H]4C(=O)O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K12 compound treatment 0.312 0.0569 3.06 3.0579 1.0 3212059 TimTec1_004104 Cc1cccc(OCCNC(=O)c2cccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K13 compound treatment 0.284 0.0289 1.55 1.5532 1.0 1300948 TimTec1_004105 COC(=O)c1c(NC(=O)C)sc2CCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K14 compound treatment 0.259 0.0039 0.21 0.2098 1.0 3085318 TimTec1_004106 CCN(CC)C(=O)c1nn(C)c(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K15 compound treatment 0.356 0.101 5.42 5.4223 1.0 1423050 TimTec1_004107 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)Nc3cccc(Br)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K16 compound treatment 0.277 0.0219 1.18 1.177 1.0 3212060 TimTec1_004108 OCCCc1nnc(SC(=O)O)n1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K17 compound treatment 0.263 0.0079 0.42 0.4247 1.0 3085320 TimTec1_004109 Cc1cc(C)n(n1)C(=O)CSc2ccc(cc2)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K18 compound treatment 0.296 0.0409 2.2 2.1981 1.0 3212061 TimTec1_004110 Fc1ccc(cc1)S(=O)(=O)Nc2nonc2NS(=O)(=O)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K19 compound treatment 0.263 0.0079 0.42 0.4247 1.0 3085322 TimTec1_004111 CC1(C)[C@H]2CCC1(CS(=O)(=O)N(C3CCCCC3)C4CCCCC4)C(O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K20 compound treatment 0.447 0.192 10.31 10.3125 1.0 3212062 TimTec1_004112 COC(=O)C/1=C(C)NC(=O)\C1=C/c2ccc(cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K21 compound treatment 0.542 0.287 15.42 15.4176 1.0 1494618 TimTec1_004113 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(C)cc4C)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K22 compound treatment 0.262 0.0069 0.37 0.371 1.0 1021964 TimTec1_004114 NCCc1ccc(cc1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K23 mock treatment 0.264 0.0089 0.48 0.4784 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 K24 mock treatment 0.262 0.0069 0.37 0.371 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L01 compound treatment 0.287 0.0319 1.71 1.7144 1.0 1265817 TimTec1_004115 Cc1ccc(NC2OC(CO)C(O)C2O)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L02 compound treatment 0.274 0.0189 1.02 1.0158 1.0 3212063 TimTec1_004116 O=C(CSc1nnc(c2ccccc2)n1CCN3CCOCC3)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L03 compound treatment 0.269 0.0139 0.75 0.7471 1.0 3085326 TimTec1_004117 Cc1cc(C(=O)O)c(CSCc2cc(oc2C)C(=O)O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L04 compound treatment 0.259 0.0039 0.21 0.2098 1.0 1576521 TimTec1_004118 COc1ccc(CN(CCCN)CCC2(CC(C)N(C)CC2C)c3ccccc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L05 compound treatment 0.291 0.0359 1.93 1.9294 1.0 3212064 TimTec1_004119 CCCc1cc2OCOc2cc1NC(=O)C(C)(C)C(=O)Nc3cc4OCOc4cc3CCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L06 compound treatment 0.521 0.266 14.29 14.2891 1.0 3085328 TimTec1_004120 Oc1cccc(c1)c2cc(=O)c3cc(O)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L07 compound treatment 0.263 0.0079 0.42 0.4247 1.0 3085330 TimTec1_004121 Nc1cccc(c1)C2OCCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L08 compound treatment 0.292 0.0369 1.98 1.9831 1.0 3212065 TimTec1_004122 Cc1cc(=O)[nH]c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L09 compound treatment 0.26 0.0049 0.26 0.2635 1.0 1408553 TimTec1_004123 CC(C)NC(=O)C(Cc1ccccc1)N2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L10 compound treatment 0.284 0.0289 1.55 1.5532 1.0 3085403 TimTec1_004124 Cc1cc2COC(=O)c2c(Sc3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L11 compound treatment 0.337 0.0819 4.4 4.4013 1.0 3212066 TimTec1_004125 O=C/1OC(=N\C1=C/2\OC(=O)c3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L12 compound treatment 0.308 0.0529 2.84 2.8429 1.0 1563075 TimTec1_004126 O=C1CCCC2=C1C(Nc3ccc4ccccc4c23)c5cccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L13 compound treatment 0.411 0.156 8.38 8.3779 1.0 3085407 TimTec1_004127 Fc1ccc(C/N=C\c2cc3ccccc3nc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L14 compound treatment 0.348 0.0929 4.99 4.9924 1.0 1705522 TimTec1_004128 Oc1ccc(cc1CN2CCN(CCC#N)CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L15 compound treatment 0.37 0.115 6.17 6.1747 1.0 3085409 TimTec1_004129 COc1cc(ccc1O)c2nc(S)nc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L16 compound treatment 0.292 0.0369 1.98 1.9831 1.0 1136694 TimTec1_004130 Cc1cccc(NC(=O)CNC(=O)OCc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L17 compound treatment 0.264 0.0089 0.48 0.4784 1.0 1605978 TimTec1_004131 Cn1c(=O)c(c2cc(c3ccccc3C(=O)NN)n(n2)c4ccccc4)c(O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L18 compound treatment 0.435 0.18 9.67 9.6676 1.0 3085412 TimTec1_004132 CCOc1ccc(cc1)[C@H]2[C@@H]3CN(Cc4ccccc4)CC=C3C(=C(N)C2(C#N)C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L19 compound treatment 0.31 0.0549 2.95 2.9504 1.0 3212067 TimTec1_004133 C(NC1=NC=N2CCn3cnc1c23)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L20 compound treatment 0.282 0.0269 1.45 1.4457 1.0 1912645 TimTec1_004134 CC(=O)n1nc(C)cc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L21 compound treatment 0.429 0.174 9.35 9.3452 1.0 3085414 TimTec1_004135 Sc1nnc(COc2ccccc2Cl)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L22 compound treatment 0.31 0.0549 2.95 2.9504 1.0 1409212 TimTec1_004136 COc1ccccc1CNC(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L23 mock treatment 0.257 0.0019 0.1 0.1023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 L24 mock treatment 0.256 9.03E-4 0.05 0.0485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M01 compound treatment 0.277 0.0219 1.18 1.177 1.0 1608236 TimTec1_004137 CC(C)c1ccc(cc1)c2csc3ncn(N)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M02 compound treatment 0.531 0.276 14.83 14.8265 1.0 3212068 TimTec1_004138 Cn1c(=O)n(C)c2cc(CN3C(=O)c4ccccc4C3=O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M03 compound treatment 0.259 0.0039 0.21 0.2098 1.0 1233601 TimTec1_004139 Cc1nn(c2CC(CC(=O)c12)c3ccco3)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M04 compound treatment 0.296 0.0409 2.2 2.1981 1.0 1300398 TimTec1_004140 O=C(NC1CC1)c2ccc(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M05 compound treatment 0.237 -0.0181 -0.97 -0.9725 -1.0 1190193 TimTec1_004141 Cc1[nH]c2ccccc2c1C(N3CCN(CC3)c4ccccc4)c5cccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M06 compound treatment 0.265 0.0099 0.53 0.5322 1.0 1227000 TimTec1_004142 NNc1ccc2[nH]c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M07 compound treatment 0.352 0.0969 5.21 5.2074 1.0 1560140 TimTec1_004143 Fc1ccc(Cn2cnc3ccccc3c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M08 compound treatment 0.274 0.0189 1.02 1.0158 1.0 3212133 TimTec1_004144 CC(=O)O[C@@]1(CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C)C(=O)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M09 compound treatment 0.467 0.212 11.39 11.3872 1.0 3085420 TimTec1_004145 Brc1ccc(o1)C(=O)Nc2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M10 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 3212134 TimTec1_004146 CCC1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(OC)c(OC)cc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M11 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 3085422 TimTec1_004147 C[C@@H]1CC2(CCCN2Cc3ccccc3)C[C@H]1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M12 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 3085423 TimTec1_004148 O=C(NCCN1CCN=C1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M13 compound treatment 0.261 0.0059 0.32 0.3172 1.0 1325497 TimTec1_004149 CCC(=O)Nc1ccccc1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M14 compound treatment 0.331 0.0759 4.08 4.0789 1.0 3085425 TimTec1_004150 O=c1cc(CSc2nc3ccccc3s2)c4ccccc4[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M15 compound treatment 0.259 0.0039 0.21 0.2098 1.0 1732529 TimTec1_004151 CC(C)NS(=O)(=O)c1ccc(NC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M16 compound treatment 0.311 0.0559 3.0 3.0041 1.0 1321742 TimTec1_004152 CC(C)(C)NC(=O)CSc1nc2ccccc2n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M17 compound treatment 0.356 0.101 5.42 5.4223 1.0 3212135 TimTec1_004153 O=S(=O)(NCCCn1ccnc1)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M18 compound treatment 0.351 0.0959 5.15 5.1536 1.0 3084387 TimTec1_004154 Cc1ccc(cc1S(=O)(=O)NC(C)(C)CO)c2nnc(N3CCOCC3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M19 compound treatment 0.313 0.0579 3.11 3.1116 1.0 1026799 TimTec1_004155 OC(=O)c1ccc(Br)c(c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M20 compound treatment 0.394 0.139 7.46 7.4644 1.0 3212136 TimTec1_004156 OC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M21 compound treatment 0.315 0.0599 3.22 3.2191 1.0 3084389 TimTec1_004157 COc1ccc(cc1)C2CC(=O)Nc3cc4OCOc4cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M22 compound treatment 0.265 0.0099 0.53 0.5322 1.0 3069528 TimTec1_004158 C/C=C\1/C[C@@H](C)[C@](O)(CO)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M23 mock treatment 0.254 -0.0011 -0.06 -0.0589 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 M24 mock treatment 0.261 0.0059 0.32 0.3172 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N01 compound treatment 0.239 -0.0161 -0.87 -0.865 -1.0 3212137 TimTec1_004159 OCC1OC(CC1O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N02 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 3212138 TimTec1_004160 CC/1=NNC(=O)\C1=C/c2cn(nc2c3ccc(F)cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N03 compound treatment 0.344 0.0889 4.78 4.7775 1.0 3084392 TimTec1_004161 Cn1cnnc1c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N04 compound treatment 0.272 0.0169 0.91 0.9083 1.0 3084393 TimTec1_004162 CN(Cc1ccccc1)C(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N05 compound treatment 0.336 0.0809 4.35 4.3476 1.0 3212139 TimTec1_004163 Cc1nc2ccc(NC(=O)C(C)(C)C(=O)Nc3ccc4nc(C)c(C)nc4c3)cc2nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N06 compound treatment 0.29 0.0349 1.88 1.8756 1.0 3084395 TimTec1_004164 Cc1ccccc1OCc2nnc(S)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N07 compound treatment 0.396 0.141 7.57 7.5718 1.0 3212140 TimTec1_004165 O=C(/C=C/c1cccs1)C(=C2SCCCCS2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N08 compound treatment 0.255 -9.68E-5 -0.01 -0.0052 -1.0 1485279 TimTec1_004166 CCOC(=O)C1=C(C)NC2(O)CC1C3COC2O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N09 compound treatment 0.285 0.0299 1.61 1.6069 1.0 1264107 TimTec1_004167 Cc1ccc(cc1)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N10 compound treatment 0.302 0.0469 2.52 2.5205 1.0 1616817 TimTec1_004168 CCc1nc(SCC(=O)C(C)(C)C)c(C#N)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N11 compound treatment 0.308 0.0529 2.84 2.8429 1.0 1253074 TimTec1_004169 O=C(NC(=S)NCc1ccco1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N12 compound treatment 0.521 0.266 14.29 14.2891 1.0 3084399 TimTec1_004170 Cc1[nH]c2ccccc2c1/C=N/c3c(nc4ccccn34)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N13 compound treatment 0.258 0.0029 0.16 0.156 1.0 1017704 TimTec1_004171 Nc1ncnc2[nH]c(nc12)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N14 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 3212141 TimTec1_004172 CCOC(=O)c1sc(SC#N)c(c1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N15 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 1004708 TimTec1_004173 COc1ccccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N16 compound treatment 0.3 0.0449 2.41 2.413 1.0 1222145 TimTec1_004174 CC(C)N1CC(COc2ccccc2)OC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N17 compound treatment 0.293 0.0379 2.04 2.0368 1.0 3084402 TimTec1_004175 Cc1cc(N)n(n1)c2ncnc3sc4CCCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N18 compound treatment 0.264 0.0089 0.48 0.4784 1.0 1166305 TimTec1_004176 Cc1ccc(cc1S)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N19 compound treatment 0.519 0.264 14.18 14.1816 1.0 3212142 TimTec1_004177 Cc1nc2ccccc2nc1N/C(=N/C(=O)c3ccccc3)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N20 compound treatment 0.284 0.0289 1.55 1.5532 1.0 1378550 TimTec1_004178 O=C1CCC(=O)N1CNc2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N21 compound treatment 0.332 0.0769 4.13 4.1326 1.0 3212143 TimTec1_004179 Cc1nc2ccc(NC(=O)N3CC4(C)CC3CC(C)(C)C4)cc2nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N22 compound treatment 0.262 0.0069 0.37 0.371 1.0 1205779 TimTec1_004180 NC(=O)c1cc2ccccc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N23 mock treatment 0.249 -0.0061 -0.33 -0.3276 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 N24 mock treatment 0.253 -0.0021 -0.11 -0.1127 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O01 compound treatment 0.25 -0.0051 -0.27 -0.2739 -1.0 1144219 TimTec1_004181 Cc1sc2ncnc(N3CCN(Cc4ccccc4)CC3)c2c1c5ccc(F)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O02 compound treatment 0.271 0.0159 0.85 0.8546 1.0 3084915 TimTec1_004182 COc1ccc(cc1OC)c2nnc(SC)n2CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O03 compound treatment 0.268 0.0129 0.69 0.6934 1.0 1582942 TimTec1_004183 CC1=CCC(C(C1)c2ccc(Br)cc2)(C(=O)O)C(=O)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O04 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 1277662 TimTec1_004184 COc1ccc(cc1)C(=O)NC2CCCCC2NC(=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O05 compound treatment 0.283 0.0279 1.5 1.4995 1.0 1305407 TimTec1_004185 Fc1ccc(cc1)c2csc3ncnc(Oc4ccc5ccc(=O)oc5c4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O06 compound treatment 0.27 0.0149 0.8 0.8009 1.0 3212144 TimTec1_004186 OC(=O)c1cc(ccc1Cl)N2N=C(/C(=C/c3ccc(o3)c4ccccc4)/C2=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O07 compound treatment 0.285 0.0299 1.61 1.6069 1.0 3084918 TimTec1_004187 COC(=O)c1nn(c(Br)c1C(=O)OC)c2ccc(Br)cc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O08 compound treatment 0.572 0.317 17.03 17.0297 1.0 3084920 TimTec1_004188 COc1cc(Br)c(CN(CCc2ccc(O)cc2)C(=O)C(F)(F)F)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O09 compound treatment 0.27 0.0149 0.8 0.8009 1.0 1388832 TimTec1_004189 Clc1ccccc1C(=O)NC2CCCCC2NC(=O)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O10 compound treatment 0.516 0.261 14.02 14.0204 1.0 1535096 TimTec1_004190 CC(C)c1ccc(cc1)C2C(=C(N)Oc3c2n(C(=O)C)c4ccccc34)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O11 compound treatment 0.307 0.0519 2.79 2.7892 1.0 1851014 TimTec1_004191 COc1ccc2c(Cl)c(sc2c1)C(=O)Oc3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O12 compound treatment 0.486 0.231 12.41 12.4083 1.0 1407017 TimTec1_004192 CCN(CC)c1ccc2c(c1)oc(=O)c3c(Cl)cc(=O)oc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O13 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 1440352 TimTec1_004193 OC(=O)c1ccccc1C(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O14 compound treatment 0.269 0.0139 0.75 0.7471 1.0 3084985 TimTec1_004194 COC(=O)Nc1ncc(CN2CCC(C)CC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O15 compound treatment 0.267 0.0119 0.64 0.6397 1.0 1441746 TimTec1_004195 O=C(Cc1ccccc1)NN(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O16 compound treatment 0.349 0.0939 5.05 5.0462 1.0 1247973 TimTec1_004196 CC1CCCCN1C(=O)c2ccccc2NS(=O)(=O)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O17 compound treatment 0.436 0.181 9.72 9.7214 1.0 3084989 TimTec1_004197 CCOCC(O)CSc1nc(C)cc(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O18 compound treatment 0.317 0.0619 3.33 3.3265 1.0 1089162 TimTec1_004198 OCC1OC(C(O)C1O)n2ccc(NC(=O)c3ccccc3)nc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O19 compound treatment 0.258 0.0029 0.16 0.156 1.0 3084991 TimTec1_004199 CC1(C)[C@H]2CCC1(CS(=O)(=O)N)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O20 compound treatment 0.31 0.0549 2.95 2.9504 1.0 3212307 TimTec1_004200 OC(=O)c1cc(cc(c1)c2ccc(/C=N\c3ccc4[nH]c(=O)[nH]c4c3)o2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O21 compound treatment 0.266 0.0109 0.59 0.5859 1.0 3084993 TimTec1_004201 Clc1ccc(cc1)C2NC(=O)NC(=C2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O22 compound treatment 0.272 0.0169 0.91 0.9083 1.0 1067834 TimTec1_004202 NCCC(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O23 mock treatment 0.266 0.0109 0.59 0.5859 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 O24 mock treatment 0.268 0.0129 0.69 0.6934 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P01 compound treatment 0.237 -0.0181 -0.97 -0.9725 -1.0 3212216 TimTec1_004203 CC(C)(C)C1(O)CC2OC(=O)CC23C(=O)OC4OC(=O)C(O)C413 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P02 compound treatment 0.444 0.189 10.15 10.1513 1.0 1735319 TimTec1_004204 CCOC(=O)c1nn(c2ccc(Cl)cc2)c(=N)c3c(N)c(C#N)c(N)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P03 compound treatment 0.251 -0.0041 -0.22 -0.2202 -1.0 3212217 TimTec1_004205 COc1cc2C[C@@H]3N(C)CCc4c(N)c(OC)c(OC)c(-c2cc1OC)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P04 compound treatment 0.557 0.302 16.22 16.2236 1.0 3084996 TimTec1_004206 Oc1ccc2cc(c3cccc(Br)c3)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P05 compound treatment 0.438 0.183 9.83 9.8288 1.0 3212218 TimTec1_004207 Cc1ccc(cc1Cl)C(=O)NC2CS(=O)(=O)CC2NC(=O)c3ccc(C)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P06 compound treatment 0.24 -0.0151 -0.81 -0.8113 -1.0 1055533 TimTec1_004208 NC(=O)c1c(F)c(F)c(N)c(F)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P07 compound treatment 0.362 0.107 5.74 5.7448 1.0 3212219 TimTec1_004209 OC1=CC(O)(N(/N=C/2\C(=O)Nc3ccc(Br)cc23)C1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P08 compound treatment 0.295 0.0399 2.14 2.1443 1.0 3084999 TimTec1_004210 CC/C(=N/O)/C(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P09 compound treatment 0.391 0.136 7.3 7.3032 1.0 1118292 TimTec1_004211 COc1ccc(NC(=O)CC(=O)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P10 compound treatment 0.24 -0.0151 -0.81 -0.8113 -1.0 3212220 TimTec1_004212 CC1(C)N2CN(CCCCN3CN4N(C3)C4(C)C)CN21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P11 compound treatment 0.261 0.0059 0.32 0.3172 1.0 3085001 TimTec1_004213 FC(F)(F)c1ccccc1NCn2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P12 compound treatment 0.281 0.0259 1.39 1.392 1.0 1471541 TimTec1_004214 OC(=O)CCNc1ccc(Br)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P13 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 3212221 TimTec1_004215 CCOC(=O)c1[nH]c(=O)[nH]c1CC2C(=O)CC(C)(C)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P14 compound treatment 0.248 -0.0071 -0.38 -0.3814 -1.0 1913403 TimTec1_004216 CN(C)c1nc(OC(C(F)(F)F)C(F)(F)F)nc(n1)N(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P15 compound treatment 0.271 0.0159 0.85 0.8546 1.0 1008937 TimTec1_004217 C(COc1ccccc1)Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P16 compound treatment 0.369 0.114 6.12 6.1209 1.0 1247888 TimTec1_004218 O=C(CSc1ccccn1)NCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P17 compound treatment 0.287 0.0319 1.71 1.7144 1.0 1266971 TimTec1_004219 C(Sc1nc2ccccc2o1)c3cccc(Oc4ccccc4)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P18 compound treatment 0.466 0.211 11.33 11.3335 1.0 3212222 TimTec1_004220 Cc1nnc(SCc2ccc(F)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P19 compound treatment 0.484 0.229 12.3 12.3008 1.0 1377201 TimTec1_004221 O=C1N(CCNS(=O)(=O)c2ccc3oc4ccccc4c3c2)Cc5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P20 compound treatment 0.256 9.03E-4 0.05 0.0485 1.0 1474244 TimTec1_004222 CC1(C)Cc2c(CO1)c(nc3sc(cc23)C(=O)O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P21 compound treatment 0.405 0.15 8.06 8.0555 1.0 3212223 TimTec1_004223 COc1cccc2C(CC(=O)c3ccc(O)cc3)C4=C(CC(C)(C)CC4=O)Oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P22 compound treatment 0.278 0.0229 1.23 1.2308 1.0 3085007 TimTec1_004224 CC(=CCS(=O)(=O)c1ccccc1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P23 mock treatment 0.255 -9.68E-5 -0.01 -0.0052 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2074 P24 mock treatment 0.263 0.0079 0.42 0.4247 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A01 compound treatment 0.227 -0.0155 -0.83 -0.8321 -1.0 3085008 TimTec1_004225 CC(=C)CS(=O)(=O)c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A02 compound treatment 0.24 -0.00248 -0.13 -0.1335 -1.0 1397478 TimTec1_004226 COc1ccc(NC(=O)C2C(=C2c3ccccc3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A03 compound treatment 0.274 0.0315 1.69 1.6936 1.0 1295145 TimTec1_004227 CCOC(=O)C1(C(CC(=O)CC1c2ccccc2)c3ccccc3)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A04 compound treatment 0.511 0.269 14.43 14.4295 1.0 1717498 TimTec1_004228 CC(C)(C)C(=O)NCCc1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A05 compound treatment 0.491 0.249 13.35 13.3547 1.0 3212224 TimTec1_004229 CC(C)(COC(=O)c1ccccc1)NC2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A06 compound treatment 0.24 -0.00248 -0.13 -0.1335 -1.0 1324852 TimTec1_004230 CC1CC(O)(Cc2ccc(C)cc2)C(C)CN1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A07 compound treatment 0.24 -0.00248 -0.13 -0.1335 -1.0 1528736 TimTec1_004231 COc1cccc(CC(C)C(=O)N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A08 compound treatment 0.375 0.133 7.12 7.1211 1.0 3212225 TimTec1_004232 COc1c(ccc2ccccc12)C(=O)NCCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A09 compound treatment 0.232 -0.0105 -0.56 -0.5634 -1.0 3212226 TimTec1_004233 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4CC(=O)CCC4(C)C3CCC21C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A10 compound treatment 0.457 0.215 11.53 11.5276 1.0 1391256 TimTec1_004234 O=C(COc1cccc(OCC(=O)Nc2ccccn2)c1)Nc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A11 compound treatment 0.283 0.0405 2.18 2.1773 1.0 3085079 TimTec1_004235 CN(CP(=O)(O)CN1CCCC1=O)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A12 compound treatment 0.246 0.00352 0.19 0.1889 1.0 1155490 TimTec1_004236 OC(=O)CN(CC(=O)O)c1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A13 compound treatment 0.273 0.0305 1.64 1.6399 1.0 3085081 TimTec1_004237 O/N=C/C(=O)Nc1ccccc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A14 compound treatment 0.299 0.0565 3.04 3.0371 1.0 1152383 TimTec1_004238 COc1ccc(NC(=O)C2C3C2C4CCC3C4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A15 compound treatment 0.283 0.0405 2.18 2.1773 1.0 1199333 TimTec1_004239 O=C(NCc1ccccc1)C2CC2(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A16 compound treatment 0.329 0.0865 4.65 4.6492 1.0 3212227 TimTec1_004240 Cc1ccc(cc1)C(=O)CC(C(C#N)C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A17 compound treatment 0.382 0.14 7.5 7.4973 1.0 3085083 TimTec1_004241 O=c1[nH][nH]c(=O)c2c(/N=C/c3cccc4ccccc34)cccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A18 compound treatment 0.306 0.0635 3.41 3.4132 1.0 3212228 TimTec1_004242 COc1ccc(OC)c(NC(=O)C2C3CC/C=C/CC\C=C/CCC23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A19 compound treatment 0.459 0.217 11.64 11.6351 1.0 3085086 TimTec1_004243 Brc1ccccc1NC(=O)CSc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A20 compound treatment 0.528 0.286 15.34 15.343 1.0 3212229 TimTec1_004244 COc1ccc(cc1)N2C(=O)C(=CC2(OC)c3ccccc3)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A21 compound treatment 0.484 0.242 12.98 12.9786 1.0 3085088 TimTec1_004245 CN(C)/N=C/c1ccc(OC(=O)c2ccc(Br)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A22 compound treatment 0.532 0.29 15.56 15.558 1.0 3212230 TimTec1_004246 O=C(CSc1ccccn1)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A23 mock treatment 0.247 0.00452 0.24 0.2427 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 A24 mock treatment 0.289 0.0465 2.5 2.4997 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B01 compound treatment 0.283 0.0405 2.18 2.1773 1.0 1674437 TimTec1_004247 CCN1N=C(C)C=C(C)n2c1nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B02 compound treatment 0.259 0.0165 0.89 0.8875 1.0 1696382 TimTec1_004248 Cc1ccc(NC(=O)C2C3CCCCC=CC23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B03 compound treatment 0.431 0.189 10.13 10.1305 1.0 3212231 TimTec1_004249 CCC1SC(=NC1=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B04 compound treatment 0.271 0.0285 1.53 1.5324 1.0 1427335 TimTec1_004250 C=CCN(CC=C)S(=O)(=O)c1ncn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B05 compound treatment 0.285 0.0425 2.28 2.2847 1.0 3085092 TimTec1_004251 Nc1cc(ccc1OCc2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B06 compound treatment 0.327 0.0845 4.54 4.5417 1.0 3212232 TimTec1_004252 CN(C)c1c(C(=C(C#N)C#N)C#N)c2ccccc2n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B07 compound treatment 0.278 0.0355 1.91 1.9086 1.0 3085094 TimTec1_004253 OC(=O)c1ccc(CSc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B08 compound treatment 0.257 0.0145 0.78 0.7801 1.0 1347619 TimTec1_004254 CCC1NC(=S)NC(=C1C(=O)c2ccccc2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B09 compound treatment 0.257 0.0145 0.78 0.7801 1.0 3085159 TimTec1_004255 CCOc1ccc(cc1NC(=O)C)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B10 compound treatment 0.24 -0.00248 -0.13 -0.1335 -1.0 1518737 TimTec1_004256 CCC(=O)N1N=C2CC(C)(C)OCC2C1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B11 compound treatment 0.286 0.0435 2.34 2.3385 1.0 1335526 TimTec1_004257 CCOC(=O)c1nnn(c1CN2CCSCC2)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B12 compound treatment 0.396 0.154 8.25 8.2496 1.0 1291333 TimTec1_004258 CC1(C)NN(C(=S)N1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B13 compound treatment 0.261 0.0185 1.0 0.995 1.0 1385793 TimTec1_004259 Cc1nn(c(O)c1C2CC(=O)N(C2=O)c3ccccc3)c4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B14 compound treatment 0.259 0.0165 0.89 0.8875 1.0 1213104 TimTec1_004260 CC(CC(=O)C1C(C)C=CCC1(C)C)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B15 compound treatment 0.27 0.0275 1.48 1.4787 1.0 3212233 TimTec1_004261 CN/C(=N\C)/SC1CC(=O)N(C1=O)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B16 compound treatment 0.561 0.319 17.12 17.1164 1.0 1345990 TimTec1_004262 CCC(=O)Nc1ccccc1C(=O)OCC(=O)Nc2nc3ccc(cc3s2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B17 compound treatment 0.309 0.0665 3.57 3.5744 1.0 1326177 TimTec1_004263 COc1cccc2c(CCN)c[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B18 compound treatment 0.174 -0.0685 -3.68 -3.6802 -1.0 3085165 TimTec1_004264 CCC1=C(C)/C(=C\c2[nH]c(C)c(CC)c2C)/N=C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B19 compound treatment 0.565 0.323 17.33 17.3313 1.0 3212234 TimTec1_004265 CCOc1cc(/C=C/2\OC(=O)c3c2cc(C)[nH]c3=S)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B20 compound treatment 0.33 0.0875 4.7 4.7029 1.0 1379087 TimTec1_004266 Cc1ccc(OCc2nn(CN3CCC4(CC3)OCCO4)c(=S)n2C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B21 compound treatment 0.26 0.0175 0.94 0.9413 1.0 1413553 TimTec1_004267 CCC(Sc1nnc(C)c(=O)[nH]1)C(=O)Nc2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B22 compound treatment 0.273 0.0305 1.64 1.6399 1.0 3212308 TimTec1_004268 COc1ccc(Br)cc1S(=O)(=O)NCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B23 mock treatment 0.247 0.00452 0.24 0.2427 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 B24 mock treatment 0.234 -0.00848 -0.46 -0.4559 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C01 compound treatment 0.25 0.00752 0.4 0.4039 1.0 1539639 TimTec1_004269 COc1ccc(cc1)C(N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C02 compound treatment 0.622 0.38 20.39 20.3944 1.0 1192605 TimTec1_004270 O=C(NCCc1ccccc1)c2ccc(o2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C03 compound treatment 0.427 0.185 9.92 9.9155 1.0 3085169 TimTec1_004271 NC/1=C(C#N)C(=N)S\C1=C\c2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C04 compound treatment 0.525 0.283 15.18 15.1818 1.0 3212309 TimTec1_004272 CCCCC(CC)CNC1=NS(=O)(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C05 compound treatment 0.283 0.0405 2.18 2.1773 1.0 1436367 TimTec1_004273 CSc1nc2nc(N)nc(N)c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C06 compound treatment 0.462 0.22 11.8 11.7963 1.0 3212310 TimTec1_004274 COc1ccc(Cc2nnc(S)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C07 compound treatment 0.273 0.0305 1.64 1.6399 1.0 3085173 TimTec1_004275 OC(=O)CSC1=CC(=O)N(C1=O)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C08 compound treatment 0.248 0.00552 0.3 0.2964 1.0 1438726 TimTec1_004276 Cc1ccnc(c1)N2C(=O)OC(C)(C)C2(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C09 compound treatment 0.289 0.0465 2.5 2.4997 1.0 1517107 TimTec1_004277 CC(=O)N1CCN2C(=O)C1CCCC(=O)c3cc(ccc23)C4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C10 compound treatment 0.498 0.256 13.73 13.7309 1.0 1430711 TimTec1_004278 COC(=O)c1cccc(NC(=O)COC(=O)c2cc3ccccc3o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C11 compound treatment 0.25 0.00752 0.4 0.4039 1.0 1141099 TimTec1_004279 OC(=O)CCS(=O)(=O)c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C12 compound treatment 0.321 0.0785 4.22 4.2193 1.0 3085175 TimTec1_004280 Cc1cccc(c1)n2nn[nH]c2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C13 compound treatment 0.291 0.0485 2.61 2.6072 1.0 3212311 TimTec1_004281 Brc1ccc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C14 compound treatment 0.251 0.00852 0.46 0.4576 1.0 1600116 TimTec1_004282 NS(=O)(=O)c1ncn(Cc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C15 compound treatment 0.41 0.168 9.0 9.002 1.0 1916017 TimTec1_004283 Nc1ccc(cc1)c2cnc(nc2)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C16 compound treatment 0.279 0.0365 1.96 1.9623 1.0 1129774 TimTec1_004284 CCOC(=O)c1oc2ccccc2c1NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C17 compound treatment 0.368 0.126 6.74 6.745 1.0 1248984 TimTec1_004285 COc1ccc(NC(=O)c2ccc3ccccc3c2OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C18 compound treatment 0.247 0.00452 0.24 0.2427 1.0 3085247 TimTec1_004286 CC(NC(=O)Nc1ccccc1Br)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C19 compound treatment 0.257 0.0145 0.78 0.7801 1.0 1510374 TimTec1_004287 COc1ccc(NC(=O)C2CCC(=O)N2C(=O)OCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C20 compound treatment 0.25 0.00752 0.4 0.4039 1.0 3085249 TimTec1_004288 CC1(C)Cc2ccccc2C(=N1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C21 compound treatment 0.268 0.0255 1.37 1.3712 1.0 1404871 TimTec1_004289 O=C(N1CCSC1c2ccccc2)c3cc4ccccc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C22 compound treatment 0.261 0.0185 1.0 0.995 1.0 1143185 TimTec1_004290 CC(C)(C)C(=O)N1CCCC1C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C23 mock treatment 0.258 0.0155 0.83 0.8338 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 C24 mock treatment 0.245 0.00252 0.14 0.1352 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D01 compound treatment 0.325 0.0825 4.43 4.4342 1.0 3212312 TimTec1_004291 CCC(SC1=NC(=O)C(C(=O)N1)c2ccccc2)C(=O)Nc3sc4CCCCc4c3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D02 compound treatment 0.363 0.121 6.48 6.4763 1.0 1681507 TimTec1_004292 S=C(SCc1ccc(CSC(=S)N2CCOCC2)cc1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D03 compound treatment 0.26 0.0175 0.94 0.9413 1.0 1369855 TimTec1_004293 CCC(=O)N1CCC(CC1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D04 compound treatment 0.371 0.129 6.91 6.9062 1.0 1327254 TimTec1_004294 O=C1C(C(=O)c2ccccc12)C3=Nc4ccccc4NC(C3)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D05 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1670837 TimTec1_004295 OC(C#CCN1CCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D06 compound treatment 0.496 0.254 13.62 13.6234 1.0 3085254 TimTec1_004296 Nc1ccc2nc(SCC(=O)c3ccc(F)cc3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D07 compound treatment 0.293 0.0505 2.71 2.7146 1.0 1149209 TimTec1_004297 Cn1ccnc1SCC(=O)Nc2ccccc2Oc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D08 compound treatment 0.257 0.0145 0.78 0.7801 1.0 1583796 TimTec1_004298 OC(=O)c1ccc(cc1)c2cnc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D09 compound treatment 0.264 0.0215 1.16 1.1562 1.0 1479857 TimTec1_004299 Nc1ccc(OCC(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D10 compound treatment 0.518 0.276 14.81 14.8057 1.0 1457410 TimTec1_004300 C(Nc1ccc2oc(nc2c1)c3ccccc3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D11 compound treatment 0.217 -0.0255 -1.37 -1.3694 -1.0 3085258 TimTec1_004301 CC(=O)OC1(CN2CCC1CC2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D12 compound treatment 0.243 5.16E-4 0.03 0.0277 1.0 1325596 TimTec1_004302 CC(=O)N1C(O)C(O)N(C(=O)C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D13 compound treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 3085259 TimTec1_004303 CNC(=N)NC(=O)Nc1c(C)cccc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D14 compound treatment 0.256 0.0135 0.73 0.7263 1.0 1635468 TimTec1_004304 COc1ccc2n(c(C)c(C(=O)N3CCN(C)CC3)c2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D15 compound treatment 0.241 -0.00148 -0.08 -0.0797 -1.0 1665310 TimTec1_004305 CC1(C)CC(=O)CC(=C1)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D16 compound treatment 0.363 0.121 6.48 6.4763 1.0 1262068 TimTec1_004306 Cc1cc(=O)oc2c3c(OC(=O)c4ccccc4)coc3c(NC(=O)c5ccccc5)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D17 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1639736 TimTec1_004307 CC(C)OC(=O)C1C(C2CC1C=C2)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D18 compound treatment 0.241 -0.00148 -0.08 -0.0797 -1.0 3212313 TimTec1_004308 O=C(CSc1nnc[nH]1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D19 compound treatment 0.243 5.16E-4 0.03 0.0277 1.0 1018938 TimTec1_004309 O=C(N1CCN(CC1)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D20 compound treatment 0.236 -0.00648 -0.35 -0.3484 -1.0 1028190 TimTec1_004310 COc1ccc(CC(O)CN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D21 compound treatment 0.254 0.0115 0.62 0.6189 1.0 1610412 TimTec1_004311 CC(C)(C)OC(=O)N1CC(O)CC1C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D22 compound treatment 0.287 0.0445 2.39 2.3922 1.0 1636298 TimTec1_004312 Cn1ccnc1SCC(=O)N2c3ccccc3CCc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D23 mock treatment 0.246 0.00352 0.19 0.1889 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 D24 mock treatment 0.234 -0.00848 -0.46 -0.4559 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E01 compound treatment 0.229 -0.0135 -0.72 -0.7246 -1.0 3212314 TimTec1_004313 CC(=O)NCC(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E02 compound treatment 0.336 0.0935 5.03 5.0254 1.0 1202468 TimTec1_004314 O=C(NCN1CCN(Cc2ccccc2)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E03 compound treatment 0.299 0.0565 3.04 3.0371 1.0 3085337 TimTec1_004315 COc1ccc(/N=C/c2ccc(Sc3ccccn3)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E04 compound treatment 0.272 0.0295 1.59 1.5861 1.0 1420647 TimTec1_004316 O=C(COC(=O)c1ccco1)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E05 compound treatment 0.347 0.105 5.62 5.6165 1.0 1547103 TimTec1_004317 CC(N1C(=O)CCC1=O)C(=O)Oc2ccc3c(C)cc(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E06 compound treatment 0.331 0.0885 4.76 4.7567 1.0 1714581 TimTec1_004318 Cc1ccc(CCP(=O)(O)CN2CCCCC2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E07 compound treatment 0.336 0.0935 5.03 5.0254 1.0 3085340 TimTec1_004319 Cc1ccc(NC(=O)CC2CCC2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E08 compound treatment 0.249 0.00652 0.35 0.3502 1.0 3212315 TimTec1_004320 Cc1cc(C)nc(n1)N2C(=C)C(C)(C)OC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E09 compound treatment 0.337 0.0945 5.08 5.0791 1.0 3085343 TimTec1_004321 Cc1sc(/N=C/c2ccc(Cl)c(Cl)c2)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E10 compound treatment 0.34 0.0975 5.24 5.2403 1.0 1671390 TimTec1_004322 Ic1ccc(Nc2nc3nonc3n4nnnc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E11 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1687107 TimTec1_004323 CN1CCC(O)(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E12 compound treatment 0.281 0.0385 2.07 2.0698 1.0 1215551 TimTec1_004324 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)cc3)C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E13 compound treatment 0.375 0.133 7.12 7.1211 1.0 1516816 TimTec1_004325 Clc1cccc(OCCN2CCN(CC2)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E14 compound treatment 0.358 0.116 6.21 6.2076 1.0 3212316 TimTec1_004326 O=C(CCCc1ccccc1)NC2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E15 compound treatment 0.237 -0.00548 -0.29 -0.2947 -1.0 1919871 TimTec1_004327 CCS(=O)(=O)C(=C1Nc2ccccc2N1)S(=O)(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E16 compound treatment 0.268 0.0255 1.37 1.3712 1.0 1212477 TimTec1_004328 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(C)cc32)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E17 compound treatment 0.256 0.0135 0.73 0.7263 1.0 3212317 TimTec1_004329 Nc1ccnc(c1C(=O)c2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E18 compound treatment 0.454 0.212 11.37 11.3664 1.0 1147665 TimTec1_004330 Fc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)NC4CC4)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E19 compound treatment 0.28 0.0375 2.02 2.016 1.0 1323101 TimTec1_004331 COC(=O)c1c(CC=C(C)C)c(C)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E20 compound treatment 0.34 0.0975 5.24 5.2403 1.0 3212392 TimTec1_004332 CC1CN=C(S1)N(Cc2ccccc2Cl)C(=O)Nc3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E21 compound treatment 0.267 0.0245 1.32 1.3174 1.0 3085349 TimTec1_004333 S=c1[nH]nc(Cc2ccccc2)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E22 compound treatment 0.555 0.313 16.79 16.794 1.0 1488335 TimTec1_004334 O=C(CSc1ncnc2[nH]cnc12)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E23 mock treatment 0.259 0.0165 0.89 0.8875 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 E24 mock treatment 0.25 0.00752 0.4 0.4039 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F01 compound treatment 0.256 0.0135 0.73 0.7263 1.0 3085351 TimTec1_004335 Cc1ccnc(NC(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F02 compound treatment 0.258 0.0155 0.83 0.8338 1.0 3085353 TimTec1_004336 CSc1ncc(F)c(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F03 compound treatment 0.269 0.0265 1.42 1.4249 1.0 3212393 TimTec1_004337 CCC(Sc1ccccn1)C(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F04 compound treatment 0.3 0.0575 3.09 3.0908 1.0 3084406 TimTec1_004338 Nc1ccc(OCCOc2ccc(N)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F05 compound treatment 0.283 0.0405 2.18 2.1773 1.0 1262298 TimTec1_004339 Fc1ccc(CNC(=O)C2CN(C(=O)C2)c3ccc(F)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F06 compound treatment 0.329 0.0865 4.65 4.6492 1.0 3212394 TimTec1_004340 CN(CC(COc1ccccc1)OC(=O)c2ccc(Cl)cc2)C3=NS(=O)(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F07 compound treatment 0.252 0.00952 0.51 0.5114 1.0 1118159 TimTec1_004341 Cc1ccc(OCCN)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F08 compound treatment 0.357 0.115 6.15 6.1539 1.0 1694465 TimTec1_004342 COc1ccc(cc1)c2nn(CO)c(=S)n2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F09 compound treatment 0.235 -0.00748 -0.4 -0.4022 -1.0 3084411 TimTec1_004343 O=S1(=O)N=C(N2CCNCC2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F10 compound treatment 0.262 0.0195 1.05 1.0488 1.0 1406499 TimTec1_004344 Cc1cc(C)c(COC(=O)c2nonc2N)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F11 compound treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 1497656 TimTec1_004345 CC1(C)CC(=O)C(C(O)c2ccccc2)C(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F12 compound treatment 0.402 0.16 8.57 8.5721 1.0 3084413 TimTec1_004346 O=C(CSc1nnc(o1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F13 compound treatment 0.279 0.0365 1.96 1.9623 1.0 1560213 TimTec1_004347 Clc1cccc(NC(=O)NC2CCN(C2)C3CCCCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F14 compound treatment 0.233 -0.00948 -0.51 -0.5096 -1.0 3084415 TimTec1_004348 Cc1cn(C(=O)c2ccc(Cl)cc2Cl)c(C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F15 compound treatment 0.469 0.227 12.17 12.1725 1.0 1406332 TimTec1_004349 O=C(CSc1nc2ccc(NC(=O)C3CCCCC3)cc2s1)NCC4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F16 compound treatment 0.335 0.0925 4.97 4.9716 1.0 3212395 TimTec1_004350 O=C1C2C(C3=C(CCCC3=O)N=C2c4ccccc14)c5cccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F17 compound treatment 0.247 0.00452 0.24 0.2427 1.0 1570773 TimTec1_004351 CC(C)(C)Nc1nc(NC(C)(C)C)nc(n1)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F18 compound treatment 0.314 0.0715 3.84 3.8431 1.0 1621338 TimTec1_004352 O=C(CSc1nc2ccccc2[nH]1)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F19 compound treatment 0.246 0.00352 0.19 0.1889 1.0 1630047 TimTec1_004353 O=S1(=O)CCC(C1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F20 compound treatment 0.311 0.0685 3.68 3.6819 1.0 1536902 TimTec1_004354 Cc1ccc(cc1)C(=O)C2C(=O)OC(=CC2=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F21 compound treatment 0.282 0.0395 2.12 2.1235 1.0 1248516 TimTec1_004355 Nc1nnc(SCC(=O)N2CCCCC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F22 compound treatment 0.288 0.0455 2.45 2.4459 1.0 3084420 TimTec1_004356 O=c1/c(=C\c2ccncc2)/sc3nc4ccccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F23 mock treatment 0.24 -0.00248 -0.13 -0.1335 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 F24 mock treatment 0.232 -0.0105 -0.56 -0.5634 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G01 compound treatment 0.243 5.16E-4 0.03 0.0277 1.0 1052156 TimTec1_004357 O=S(=O)(Nc1ccccn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G02 compound treatment 0.516 0.274 14.7 14.6982 1.0 1455699 TimTec1_004358 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccc(o2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G03 compound treatment 0.27 0.0275 1.48 1.4787 1.0 3084422 TimTec1_004359 CCc1ccc2oc(nc2c1)c3cc(/N=C\c4ccccc4O)ccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G04 compound treatment 0.271 0.0285 1.53 1.5324 1.0 3212396 TimTec1_004360 CSc1nsc(SC)c1NC(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G05 compound treatment 0.289 0.0465 2.5 2.4997 1.0 3084424 TimTec1_004361 O=C(CCCCN1CCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G06 compound treatment 0.261 0.0185 1.0 0.995 1.0 3212397 TimTec1_004362 FC(F)(F)C(NC(=O)c1ccccc1)(N2CCOCC2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G07 compound treatment 0.24 -0.00248 -0.13 -0.1335 -1.0 1644204 TimTec1_004363 CC(C)Nc1nc(Cl)nc(NC(C)(C)CO)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G08 compound treatment 0.273 0.0305 1.64 1.6399 1.0 1320611 TimTec1_004364 O=C(Nc1ccccn1)c2cccc(c2)N3C(=O)CCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G09 compound treatment 0.235 -0.00748 -0.4 -0.4022 -1.0 1019380 TimTec1_004365 C(N1CCCCC1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G10 compound treatment 0.247 0.00452 0.24 0.2427 1.0 1557179 TimTec1_004366 OC(=O)CCn1c2ccccc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G11 compound treatment 0.378 0.136 7.28 7.2824 1.0 1693338 TimTec1_004367 COc1ccc(cc1)c2ncccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G12 compound treatment 0.466 0.224 12.01 12.0113 1.0 1612647 TimTec1_004368 NNC(=O)c1ccc(OCC(O)CO)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G13 compound treatment 0.307 0.0645 3.47 3.467 1.0 1723169 TimTec1_004369 CCN(CC)c1ccc(Nc2cc(C)c(C#N)c3nc4ccccc4n23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G14 compound treatment 0.244 0.00152 0.08 0.0815 1.0 3084439 TimTec1_004370 N/C(=N\O)/c1cccc(n1)\C(=N\O)\N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G15 compound treatment 0.258 0.0155 0.83 0.8338 1.0 3212398 TimTec1_004371 Cn1c2N(CC(=O)c2c(=O)n(C)c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G16 compound treatment 0.541 0.299 16.04 16.0416 1.0 3084441 TimTec1_004372 C(Sc1nnc(SCc2ccccn2)s1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G17 compound treatment 0.264 0.0215 1.16 1.1562 1.0 3212399 TimTec1_004373 Fc1ccc(cc1)c2cc(nc(SCC(=O)Oc3ccccc3)c2C#N)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G18 compound treatment 0.306 0.0635 3.41 3.4132 1.0 1717375 TimTec1_004374 O=C(CCSc1nccn1Cc2ccccc2)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G19 compound treatment 0.413 0.171 9.16 9.1632 1.0 3084443 TimTec1_004375 Cc1cc(C)nc(SCC(=O)c2c(N)no[n+]2[O-])n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G20 compound treatment 0.265 0.0225 1.21 1.21 1.0 3212400 TimTec1_004376 CC1CN=C(S1)N(C(=O)Nc2ccc(Cl)cc2)c3cccc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G21 compound treatment 0.25 0.00752 0.4 0.4039 1.0 3084445 TimTec1_004377 CC(C)C(=O)NC1=NC2C(N=CN2C3CC(O)C(CO)O3)C(=N1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G22 compound treatment 0.28 0.0375 2.02 2.016 1.0 3212401 TimTec1_004378 O=C1CN(C=NN1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G23 mock treatment 0.238 -0.00448 -0.24 -0.241 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 G24 mock treatment 0.252 0.00952 0.51 0.5114 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H01 compound treatment 0.265 0.0225 1.21 1.21 1.0 1333222 TimTec1_004379 COc1ccccc1NCn2c(=O)sc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H02 compound treatment 0.255 0.0125 0.67 0.6726 1.0 1378323 TimTec1_004380 CSc1ncc(F)c(n1)N(CCO)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H03 compound treatment 0.254 0.0115 0.62 0.6189 1.0 1426454 TimTec1_004381 O=C(CNC(=O)C(c1ccccc1)c2ccccc2)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H04 compound treatment 0.268 0.0255 1.37 1.3712 1.0 3084448 TimTec1_004382 Cc1ccc(cc1)P(=O)(C)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H05 compound treatment 0.424 0.182 9.75 9.7543 1.0 1325975 TimTec1_004383 O=c1n(CCc2ccccn2)nc(c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H06 compound treatment 0.262 0.0195 1.05 1.0488 1.0 1363120 TimTec1_004384 OC(COc1ccccc1)CS(=O)(=O)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H07 compound treatment 0.259 0.0165 0.89 0.8875 1.0 1512838 TimTec1_004385 CSCCC1NC(=S)N(Cc2ccccc2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H08 compound treatment 0.455 0.213 11.42 11.4202 1.0 1461248 TimTec1_004386 Fc1ccc(cc1)C(=O)Nc2ccc3C(=O)OCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H09 compound treatment 0.256 0.0135 0.73 0.7263 1.0 1264638 TimTec1_004387 Oc1ccc2occ(C(=O)c3cccs3)c2c1CN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H10 compound treatment 0.253 0.0105 0.57 0.5651 1.0 1248397 TimTec1_004388 CCSc1nc2ccccc2n1CC(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H11 compound treatment 0.251 0.00852 0.46 0.4576 1.0 3084452 TimTec1_004389 O=C(OC[C@@H]1CCCN2CCCCC12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H12 compound treatment 0.433 0.191 10.24 10.2379 1.0 3212402 TimTec1_004390 CCOC(=O)c1[nH]c(COC(=O)C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H13 compound treatment 0.347 0.105 5.62 5.6165 1.0 1294077 TimTec1_004391 COc1ccc(cc1)C(=O)c2coc3ccc(OC)cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H14 compound treatment 0.413 0.171 9.16 9.1632 1.0 1370478 TimTec1_004392 Fc1cc2c(=O)cc[nH]c2cc1N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H15 compound treatment 0.231 -0.0115 -0.62 -0.6171 -1.0 1351428 TimTec1_004393 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)N(O)C2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H16 compound treatment 0.545 0.303 16.26 16.2566 1.0 3084456 TimTec1_004394 FC(F)(F)c1ccc2sc(S)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H17 compound treatment 0.253 0.0105 0.57 0.5651 1.0 1715297 TimTec1_004395 N#CC(CCN1CCNCC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H18 compound treatment 0.285 0.0425 2.28 2.2847 1.0 1355787 TimTec1_004396 OCCN(CCO)C(=O)CCc1[nH]c2ccccc2c1Sc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H19 compound treatment 0.296 0.0535 2.88 2.8758 1.0 3212474 TimTec1_004397 Clc1ccc(NC(=O)CSC2=NC(=O)C(C(=O)N2)c3ccccc3)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H20 compound treatment 0.239 -0.00348 -0.19 -0.1872 -1.0 3084461 TimTec1_004398 CC1CNc2ccccc2N=C1N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H21 compound treatment 0.239 -0.00348 -0.19 -0.1872 -1.0 3212475 TimTec1_004399 S=c1[nH]cnc2n(CN3CCCCC3)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H22 compound treatment 0.301 0.0585 3.14 3.1445 1.0 1451020 TimTec1_004400 OC1=C(C(=O)c2ccccc2)C3(O)N(C1=O)c4ccccc4OC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H23 mock treatment 0.247 0.00452 0.24 0.2427 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 H24 mock treatment 0.237 -0.00548 -0.29 -0.2947 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I01 compound treatment 0.254 0.0115 0.62 0.6189 1.0 3084463 TimTec1_004401 C/C(=N\N)/c1nnn(c1C)c2nonc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I02 compound treatment 0.32 0.0775 4.17 4.1656 1.0 1525911 TimTec1_004402 OP(=O)(CCc1ccccn1)CN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I03 compound treatment 0.398 0.156 8.36 8.3571 1.0 1170438 TimTec1_004403 CCN(CC)S(=O)(=O)c1ccc(cc1)c2csc(Nc3cccc(OC)c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I04 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1584075 TimTec1_004404 O=C(C1C2C1C(=O)C3OCC2O3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I05 compound treatment 0.232 -0.0105 -0.56 -0.5634 -1.0 1217640 TimTec1_004405 CN(C)Cc1cc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I06 compound treatment 0.466 0.224 12.01 12.0113 1.0 1227632 TimTec1_004406 N#CCCn1c(nc2ccccc12)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I07 compound treatment 0.259 0.0165 0.89 0.8875 1.0 1733675 TimTec1_004407 Cc1ccc(cc1C)N2NC(=O)CC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I08 compound treatment 0.408 0.166 8.89 8.8945 1.0 1603161 TimTec1_004408 COC(=O)c1ccc(NC(=O)COC(=O)c2cc3ccccc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I09 compound treatment 0.275 0.0325 1.75 1.7473 1.0 1037174 TimTec1_004409 CCOC(=O)c1cc(C(=O)OCC)c(C)nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I10 compound treatment 0.522 0.28 15.02 15.0206 1.0 1467402 TimTec1_004410 COc1ccc(NC(=O)CSc2ccc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I11 compound treatment 0.254 0.0115 0.62 0.6189 1.0 1668645 TimTec1_004411 O=C(Nc1cccc2ccccc12)OC3CCS(=O)(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I12 compound treatment 0.461 0.219 11.74 11.7426 1.0 3212476 TimTec1_004412 Cc1cc2/C(=C\c3ccc(Cl)c(Cl)c3)/OC(=O)c2c(=S)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I13 compound treatment 0.307 0.0645 3.47 3.467 1.0 1917148 TimTec1_004413 O=c1[nH]c2ccc(/N=C/c3ccc(C#Cc4ccccc4)cc3)cc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I14 compound treatment 0.259 0.0165 0.89 0.8875 1.0 1236087 TimTec1_004414 O=C(C1CN2CCC1CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I15 compound treatment 0.321 0.0785 4.22 4.2193 1.0 1912326 TimTec1_004415 CCOC(=O)C(C#N)C(=O)c1ccc(N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I16 compound treatment 0.256 0.0135 0.73 0.7263 1.0 1609648 TimTec1_004416 CCCC(OC(=O)C)C#CCN1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I17 compound treatment 0.408 0.166 8.89 8.8945 1.0 3084472 TimTec1_004417 COC(=O)CSc1nsc(SCC(=O)OC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I18 compound treatment 0.294 0.0515 2.77 2.7684 1.0 3212477 TimTec1_004418 CCC(Sc1nc(C)cc(C)n1)C(=O)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I19 compound treatment 0.279 0.0365 1.96 1.9623 1.0 1539203 TimTec1_004419 CCC1CCCCN1C(=O)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I20 compound treatment 0.236 -0.00648 -0.35 -0.3484 -1.0 1728922 TimTec1_004420 Nc1nonc1C(=O)OCC(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I21 compound treatment 0.246 0.00352 0.19 0.1889 1.0 1427907 TimTec1_004421 CCOc1ccc(OCC)c(c1)C(=O)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I22 compound treatment 0.26 0.0175 0.94 0.9413 1.0 1647970 TimTec1_004422 CCC(OC(=O)C)C#CCN1CCOCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I23 mock treatment 0.251 0.00852 0.46 0.4576 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 I24 mock treatment 0.234 -0.00848 -0.46 -0.4559 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J01 compound treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 3084477 TimTec1_004423 Cn1nnnc1SCC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J02 compound treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 3084491 TimTec1_004424 Cn1c(=O)nc2n(c3cccc(c3)C(F)(F)F)c4ccccc4cc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J03 compound treatment 0.316 0.0735 3.95 3.9506 1.0 3084494 TimTec1_004425 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J04 compound treatment 0.382 0.14 7.5 7.4973 1.0 1706033 TimTec1_004426 OC(=O)c1cccc(NC(=O)CC(=O)c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J05 compound treatment 0.44 0.198 10.61 10.6141 1.0 1279425 TimTec1_004427 CCCC(=O)Nc1nnc(Cc2ccc(Cl)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J06 compound treatment 0.259 0.0165 0.89 0.8875 1.0 1425542 TimTec1_004428 Fc1ccc(NC(=O)C2C3C2C4CCC3C4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J07 compound treatment 0.262 0.0195 1.05 1.0488 1.0 1301943 TimTec1_004429 Cc1[nH]c(=S)c(C#N)c(C)c1CC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J08 compound treatment 0.252 0.00952 0.51 0.5114 1.0 1313319 TimTec1_004430 COc1ccc(NC(=O)CC2SCCNC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J09 compound treatment 0.275 0.0325 1.75 1.7473 1.0 1169823 TimTec1_004431 CCN(CC)c1nc(Nc2ccccc2OC)nc(Nc3cc(C)ccc3C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J10 compound treatment 0.282 0.0395 2.12 2.1235 1.0 3084499 TimTec1_004432 Cc1ccc(cc1)n2c(SCC=C)nc3sc4CCCc4c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J11 compound treatment 0.336 0.0935 5.03 5.0254 1.0 1249197 TimTec1_004433 CCOC(=O)N1CCc2[nH]c3ccccc3c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J12 compound treatment 0.384 0.142 7.6 7.6048 1.0 1223335 TimTec1_004434 COc1ccc(Cl)cc1NC(=O)CCN2CCN(CC2)c3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J13 compound treatment 0.25 0.00752 0.4 0.4039 1.0 1680037 TimTec1_004435 O=c1cc(Nc2ccc(cc2)N3CCCCC3)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J14 compound treatment 0.248 0.00552 0.3 0.2964 1.0 1142790 TimTec1_004436 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)N3CCOCC3)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J15 compound treatment 0.258 0.0155 0.83 0.8338 1.0 1406310 TimTec1_004437 CCCNc1nc(NC2CCCCC2)nc(OC(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J16 compound treatment 0.249 0.00652 0.35 0.3502 1.0 3212719 TimTec1_004438 CCC(=O)NC(Nc1sc2CCCCc2c1C(=O)N)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J17 compound treatment 0.238 -0.00448 -0.24 -0.241 -1.0 1448396 TimTec1_004439 CC(C)C(NC(=O)C(c1ccccc1)c2ccccc2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J18 compound treatment 0.245 0.00252 0.14 0.1352 1.0 1655510 TimTec1_004440 Cc1ccccc1Nc2nc(Nc3ccccc3C)nc(Sc4nccn4C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J19 compound treatment 0.245 0.00252 0.14 0.1352 1.0 1576794 TimTec1_004441 CC(=O)N(Cc1ccc(cc1)S(=O)(=O)N)C2CC(=O)N(C2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J20 compound treatment 0.345 0.103 5.51 5.509 1.0 1667869 TimTec1_004442 Cc1ccccc1OCc2nnc(SCCC(=O)O)n2Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J21 compound treatment 0.243 5.16E-4 0.03 0.0277 1.0 3212720 TimTec1_004443 OCCCc1nnc(S)n1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J22 compound treatment 0.238 -0.00448 -0.24 -0.241 -1.0 3212721 TimTec1_004444 COc1ccc(/C=N/c2ccc3[nH]c(=O)[nH]c3c2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J23 mock treatment 0.238 -0.00448 -0.24 -0.241 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 J24 mock treatment 0.225 -0.0175 -0.94 -0.9395 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K01 compound treatment 0.432 0.19 10.18 10.1842 1.0 3084505 TimTec1_004445 O=C(OCCSC1=NS(=O)(=O)c2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K02 compound treatment 0.265 0.0225 1.21 1.21 1.0 3084507 TimTec1_004446 Cc1cc(C)c(C#N)c(SCC(=O)OC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K03 compound treatment 0.251 0.00852 0.46 0.4576 1.0 1649077 TimTec1_004447 O=C1OC2(CCCCC2)C(=C1)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K04 compound treatment 0.412 0.17 9.11 9.1094 1.0 3212722 TimTec1_004448 CC1=NN(C(=O)c2ccc(Cl)cc2)C(C)(O)C1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K05 compound treatment 0.229 -0.0135 -0.72 -0.7246 -1.0 3212723 TimTec1_004449 COc1ccc(/C=N/C2(CC3CC4CC(C3)C2)C4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K06 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1472188 TimTec1_004450 CCC(C)(N1CCC1=O)C(=O)Nc2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K07 compound treatment 0.306 0.0635 3.41 3.4132 1.0 3212724 TimTec1_004451 Cc1cccc2oc(nc12)c3ccc(/N=C/c4cc(ccc4O)C(=O)O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K08 compound treatment 0.253 0.0105 0.57 0.5651 1.0 1385208 TimTec1_004452 Cc1ccc(C)c(c1)S(=O)(=O)n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K09 compound treatment 0.243 5.16E-4 0.03 0.0277 1.0 1562045 TimTec1_004453 CN(c1c(C)n(C)n(c2ccccc2)c1=O)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K10 compound treatment 0.248 0.00552 0.3 0.2964 1.0 3084514 TimTec1_004454 Cc1cccc(NC(=O)c2cc(ccc2Cl)N3C(=O)C=CC3=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K11 compound treatment 0.275 0.0325 1.75 1.7473 1.0 3212887 TimTec1_004455 CC(C)CN(C(=O)Nc1ccccc1)C2=NCC(C)S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K12 compound treatment 0.397 0.155 8.3 8.3034 1.0 1735032 TimTec1_004456 COc1ccccc1Nc2nc3CCCCc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K13 compound treatment 0.269 0.0265 1.42 1.4249 1.0 1256975 TimTec1_004457 CCCCS(=O)C1CCCCC1OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K14 compound treatment 0.282 0.0395 2.12 2.1235 1.0 1277459 TimTec1_004458 COC(=O)CNc1nc(Cl)nc(n1)N2CCC(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K15 compound treatment 0.379 0.137 7.34 7.3361 1.0 1916082 TimTec1_004459 CC(=O)NC1=NN(C(S1)c2ccccc2)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K16 compound treatment 0.265 0.0225 1.21 1.21 1.0 1664793 TimTec1_004460 Cc1ccc(cc1)N2C(=C(C(C3=C2CC(C)(C)CC3)c4ccc(Cl)cc4)C(=O)N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K17 compound treatment 0.257 0.0145 0.78 0.7801 1.0 1554613 TimTec1_004461 CSc1nsc(SC)c1NC(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K18 compound treatment 0.53 0.288 15.45 15.4505 1.0 1119521 TimTec1_004462 O=C1NC(Nc2c1sc(=S)n2c3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K19 compound treatment 0.323 0.0805 4.33 4.3268 1.0 1275123 TimTec1_004463 Nc1cc(nn1CC2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K20 compound treatment 0.302 0.0595 3.2 3.1983 1.0 1161548 TimTec1_004464 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(c4ccccc4)c5ccccc5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K21 compound treatment 0.273 0.0305 1.64 1.6399 1.0 1635937 TimTec1_004465 O=C(CSn1nnnc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K22 compound treatment 0.319 0.0765 4.11 4.1118 1.0 3212796 TimTec1_004466 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K23 mock treatment 0.249 0.00652 0.35 0.3502 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 K24 mock treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L01 compound treatment 0.262 0.0195 1.05 1.0488 1.0 1434454 TimTec1_004467 CC(=O)Nc1ccc(Nc2cc(C)c3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L02 compound treatment 0.273 0.0305 1.64 1.6399 1.0 1330869 TimTec1_004468 CN1CC[C@@H]2[C@@H](C1)c3cc(C)ccc3N2C(=O)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L03 compound treatment 0.286 0.0435 2.34 2.3385 1.0 3084523 TimTec1_004469 Cc1cc(=O)oc2cc(OC(=O)CSC(=N)N)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L04 compound treatment 0.25 0.00752 0.4 0.4039 1.0 1640717 TimTec1_004470 CCC(C(O)c1ccccc1)c2nc3ccccc3n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L05 compound treatment 0.502 0.26 13.95 13.9459 1.0 3084525 TimTec1_004471 Clc1cccc(c1)C(=O)OCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L06 compound treatment 0.301 0.0585 3.14 3.1445 1.0 3212798 TimTec1_004472 CCSc1nc(c(C#N)c(=O)n1CC)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L07 compound treatment 0.247 0.00452 0.24 0.2427 1.0 1227993 TimTec1_004473 CC1(C)C2CCC3(C)OC(=O)N(N1c4ccccc4)C23C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L08 compound treatment 0.249 0.00652 0.35 0.3502 1.0 1742964 TimTec1_004474 CCOC(=O)N1CCN(CC1)C(=S)NC(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L09 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1439010 TimTec1_004475 COc1ccc(CCNC(=O)C2C(C3CC2C=C3)C(=O)O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L10 compound treatment 0.23 -0.0125 -0.67 -0.6709 -1.0 3084528 TimTec1_004476 CC1(C)CC(NC(=O)C(F)(F)F)C(NC(=O)C(F)(F)F)C(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L11 compound treatment 0.257 0.0145 0.78 0.7801 1.0 3212799 TimTec1_004477 NC(=O)/C(=N/O)/C1=NC2(CCCCC2)Cc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L12 compound treatment 0.289 0.0465 2.5 2.4997 1.0 1441377 TimTec1_004478 Clc1ccc(cc1)c2ccc(o2)C(=S)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L13 compound treatment 0.395 0.153 8.2 8.1959 1.0 1208093 TimTec1_004479 CN(C)CCOC(=O)C1(CC2c3ccccc3C1c4ccccc24)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L14 compound treatment 0.235 -0.00748 -0.4 -0.4022 -1.0 3084551 TimTec1_004480 CCOC(=O)c1c(O)c(Cl)c(C)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L15 compound treatment 0.411 0.169 9.06 9.0557 1.0 1150863 TimTec1_004481 CCOC(=O)c1c(C)c([nH]c1CN2CCOCC2)C(=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L16 compound treatment 0.299 0.0565 3.04 3.0371 1.0 3212800 TimTec1_004482 CC(=O)N1N=C(CC1c2ccc(F)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L17 compound treatment 0.241 -0.00148 -0.08 -0.0797 -1.0 1417256 TimTec1_004483 OCCNC(=O)c1c2CCCCc2nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L18 compound treatment 0.498 0.256 13.73 13.7309 1.0 1332505 TimTec1_004484 NNc1nnc2c3ccccc3[nH]c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L19 compound treatment 0.29 0.0475 2.55 2.5534 1.0 1647319 TimTec1_004485 COc1ccc(cc1)C2OC(=O)Cc3cc(OC)c(OC)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L20 compound treatment 0.452 0.21 11.26 11.259 1.0 3084552 TimTec1_004486 O=c1nc(SCCOc2ccccc2)[nH]c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L21 compound treatment 0.483 0.241 12.92 12.9248 1.0 3212801 TimTec1_004487 CC(=O)Nc1ccc2nc(C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L22 compound treatment 0.359 0.117 6.26 6.2613 1.0 1262531 TimTec1_004488 Nc1nonc1c2noc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L23 mock treatment 0.248 0.00552 0.3 0.2964 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 L24 mock treatment 0.229 -0.0135 -0.72 -0.7246 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M01 compound treatment 0.378 0.136 7.28 7.2824 1.0 3212802 TimTec1_004489 CCCc1c(C#N)c(N)[nH]c(=S)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M02 compound treatment 0.293 0.0505 2.71 2.7146 1.0 3084553 TimTec1_004490 N#Cc1ccc(nc1SCc2ccncc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M03 compound treatment 0.27 0.0275 1.48 1.4787 1.0 1912735 TimTec1_004491 CCSc1nc(C)cc(COC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M04 compound treatment 0.271 0.0285 1.53 1.5324 1.0 1677912 TimTec1_004492 OC(C1CCCN1Cc2ccccc2)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M05 compound treatment 0.23 -0.0125 -0.67 -0.6709 -1.0 1303390 TimTec1_004493 CNC(=O)C(NS(=O)(=O)c1ccc(C)cc1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M06 compound treatment 0.255 0.0125 0.67 0.6726 1.0 1611737 TimTec1_004494 CC1CN(C)CC(C1)(OC(=O)C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M07 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1011962 TimTec1_004495 OC(=O)CCC(=O)Nc1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M08 compound treatment 0.392 0.15 8.03 8.0347 1.0 1708192 TimTec1_004496 CCOC(=O)c1[nH]c(C)c(C(=O)C(C)C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M09 compound treatment 0.239 -0.00348 -0.19 -0.1872 -1.0 1647225 TimTec1_004497 CC1CCN(CC1)c2nc(nc(n2)N3CCC(C)CC3)N4CCC(C)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M10 compound treatment 0.256 0.0135 0.73 0.7263 1.0 3212803 TimTec1_004498 COc1cccc(OCCNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M11 compound treatment 0.265 0.0225 1.21 1.21 1.0 3084554 TimTec1_004499 Oc1ccccc1/C=N/c2nc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M12 compound treatment 0.462 0.22 11.8 11.7963 1.0 3212804 TimTec1_004500 CCSc1nsc(SCC)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M13 compound treatment 0.38 0.138 7.39 7.3898 1.0 3212805 TimTec1_004501 CSc1nnc2n(/N=C/c3cc4OCOc4cc3Br)cnn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M14 compound treatment 0.268 0.0255 1.37 1.3712 1.0 1631850 TimTec1_004502 O=c1[nH]cc(COCc2ccccc2)c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M15 compound treatment 0.239 -0.00348 -0.19 -0.1872 -1.0 1119024 TimTec1_004503 CC(C)(C)NC1=CC(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M16 compound treatment 0.445 0.203 10.88 10.8828 1.0 3212806 TimTec1_004504 COC(=O)c1cccc(NC(=O)COC(=O)CSc2nc(C)cc(C)n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M17 compound treatment 0.447 0.205 10.99 10.9903 1.0 3212807 TimTec1_004505 NC(=O)CSc1nsc(SCc2ccc(Cl)cc2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M18 compound treatment 0.272 0.0295 1.59 1.5861 1.0 1558723 TimTec1_004506 CC(=O)NC(Cc1ccc(F)cc1)C(=O)OCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M19 compound treatment 0.486 0.244 13.09 13.086 1.0 1121754 TimTec1_004507 CCOC(=O)c1cnn(CC2CCCCC2)c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M20 compound treatment 0.261 0.0185 1.0 0.995 1.0 1392807 TimTec1_004508 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NC3CCCCC3)C(c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M21 compound treatment 0.555 0.313 16.79 16.794 1.0 3084555 TimTec1_004509 CSc1nc2ccc(/N=C/c3ccc(Sc4nnnn4c5ccccc5)o3)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M22 compound treatment 0.281 0.0385 2.07 2.0698 1.0 1691433 TimTec1_004510 Clc1ccc(NC(=O)C2C3CCC=CCCC23)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M23 mock treatment 0.243 5.16E-4 0.03 0.0277 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 M24 mock treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N01 compound treatment 0.565 0.323 17.33 17.3313 1.0 3084556 TimTec1_004511 FC(F)(F)c1ccccc1/C=C\2/SC(=N)NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N02 compound treatment 0.306 0.0635 3.41 3.4132 1.0 1558366 TimTec1_004512 O=C(N1CCCCCC1)c2cc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N03 compound treatment 0.254 0.0115 0.62 0.6189 1.0 1395140 TimTec1_004513 Cc1ccc2[nH]c(SCC(=O)O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N04 compound treatment 0.301 0.0585 3.14 3.1445 1.0 3212808 TimTec1_004514 Clc1c(sc2ccccc12)C(=O)n3cccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N05 compound treatment 0.254 0.0115 0.62 0.6189 1.0 3084561 TimTec1_004515 Cc1nn(C(=O)Cc2ccc(Cl)cc2)c(C)c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N06 compound treatment 0.566 0.324 17.39 17.3851 1.0 1622238 TimTec1_004516 Nc1ccc(cc1F)c2nnn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N07 compound treatment 0.525 0.283 15.18 15.1818 1.0 3084563 TimTec1_004517 CCNc1nnc(CSc2nc3ccccc3s2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N08 compound treatment 0.243 5.16E-4 0.03 0.0277 1.0 1261617 TimTec1_004518 CC(=C)CSC1=C(C#N)C(C)(C)C(C#N)C(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N09 compound treatment 0.382 0.14 7.5 7.4973 1.0 3212888 TimTec1_004519 COc1cccc(c1)C2C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N10 compound treatment 0.445 0.203 10.88 10.8828 1.0 1151574 TimTec1_004520 COc1cccc(c1)N2C(=O)NC(=O)C(CCc3ccncc3)(CCc4ccncc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N11 compound treatment 0.234 -0.00848 -0.46 -0.4559 -1.0 3212889 TimTec1_004521 CCOC1CC(C)(C)NC(=S)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N12 compound treatment 0.249 0.00652 0.35 0.3502 1.0 1367122 TimTec1_004522 OC1CCN(C2CCCCC12)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N13 compound treatment 0.263 0.0205 1.1 1.1025 1.0 1402632 TimTec1_004523 CCCn1c(nc2ccccc12)c3nonc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N14 compound treatment 0.272 0.0295 1.59 1.5861 1.0 1157736 TimTec1_004524 CCOC(=O)c1cc(C(=O)NC(C)c2ccccc2)c(C)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N15 compound treatment 0.244 0.00152 0.08 0.0815 1.0 1611714 TimTec1_004525 COC(=O)C(C(=O)OC)c1ccc(C#N)c(C#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N16 compound treatment 0.55 0.308 16.53 16.5253 1.0 3212890 TimTec1_004526 COc1ccc(cc1)N(/N=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N17 compound treatment 0.37 0.128 6.85 6.8525 1.0 1271644 TimTec1_004527 OC1(CSC2=C(C#N)C(CC(=O)N21)c3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N18 compound treatment 0.279 0.0365 1.96 1.9623 1.0 1486726 TimTec1_004528 CCCS(=O)(=O)c1c(C(=O)c2ccc(C)cc2)n3cccc(N)c3c1S(=O)(=O)CCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N19 compound treatment 0.25 0.00752 0.4 0.4039 1.0 3084570 TimTec1_004529 Cc1nnnn1CC(=O)Nc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N20 compound treatment 0.267 0.0245 1.32 1.3174 1.0 1252602 TimTec1_004530 COc1ccc(Br)cc1S(=O)(=O)NCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N21 compound treatment 0.284 0.0415 2.23 2.231 1.0 3212891 TimTec1_004531 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(F)cc2)N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N22 compound treatment 0.249 0.00652 0.35 0.3502 1.0 1565486 TimTec1_004532 COc1cc(Oc2ccccc2CC=C)nc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N23 mock treatment 0.248 0.00552 0.3 0.2964 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 N24 mock treatment 0.241 -0.00148 -0.08 -0.0797 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O01 compound treatment 0.32 0.0775 4.17 4.1656 1.0 1618653 TimTec1_004533 Cc1ccc(cc1C)C(=O)c2cccc(N)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O02 compound treatment 0.292 0.0495 2.66 2.6609 1.0 3212892 TimTec1_004534 COC(=O)c1c(C)[nH]c(C)c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O03 compound treatment 0.485 0.243 13.03 13.0323 1.0 3084586 TimTec1_004535 CSc1nnc2n(/N=C/c3c[nH]c4ccccc34)cnn12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O04 compound treatment 0.284 0.0415 2.23 2.231 1.0 3212893 TimTec1_004536 NC(=O)[C@@H]1[C@@H](c2ccc(Cl)cc2)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O05 compound treatment 0.478 0.236 12.66 12.6561 1.0 1780136 TimTec1_004537 CCOC(=O)c1c(C)cc(C)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O06 compound treatment 0.245 0.00252 0.14 0.1352 1.0 1363495 TimTec1_004538 CN(Cn1nc(O)ccc1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O07 compound treatment 0.477 0.235 12.6 12.6024 1.0 3084613 TimTec1_004539 NC1=NN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O08 compound treatment 0.256 0.0135 0.73 0.7263 1.0 1493858 TimTec1_004540 COc1ccc(cc1OC)C2=C(N)C(=O)NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O09 compound treatment 0.26 0.0175 0.94 0.9413 1.0 3212894 TimTec1_004541 Cc1ccccc1/C=N/N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O10 compound treatment 0.494 0.252 13.52 13.516 1.0 1029950 TimTec1_004542 CN(C)c1ccc(cc1)C(=NO)c2ccc(cc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O11 compound treatment 0.249 0.00652 0.35 0.3502 1.0 1641866 TimTec1_004543 Cc1cc(C)c(cc1S(=O)(=O)N)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O12 compound treatment 0.499 0.257 13.78 13.7846 1.0 3212895 TimTec1_004544 O=C(CSc1ccccn1)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O13 compound treatment 0.253 0.0105 0.57 0.5651 1.0 3084617 TimTec1_004545 O=C(CSc1ncn[nH]1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O14 compound treatment 0.269 0.0265 1.42 1.4249 1.0 1421449 TimTec1_004546 NC(=O)Cc1ccc(NC(=O)CCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O15 compound treatment 0.256 0.0135 0.73 0.7263 1.0 1919218 TimTec1_004547 OC(=O)CCCC(=O)Nc1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O16 compound treatment 0.276 0.0335 1.8 1.8011 1.0 3084620 TimTec1_004548 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=S)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O17 compound treatment 0.548 0.306 16.42 16.4178 1.0 1239543 TimTec1_004549 O=C(CSc1nc2ccccc2o1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O18 compound treatment 0.268 0.0255 1.37 1.3712 1.0 1529100 TimTec1_004550 CCn1cc(c(C#N)c1NC(=O)C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O19 compound treatment 0.46 0.218 11.69 11.6889 1.0 3084622 TimTec1_004551 Clc1ccc(OCCNC(=O)c2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O20 compound treatment 0.299 0.0565 3.04 3.0371 1.0 1322941 TimTec1_004552 Cc1cc(C)n(NC2=CC(=O)CC(C)(C)C2)c(=O)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O21 compound treatment 0.265 0.0225 1.21 1.21 1.0 3212896 TimTec1_004553 CCN/C(=N/CC)/SC1CC(=O)N(C1=O)c2ccc(OCC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O22 compound treatment 0.311 0.0685 3.68 3.6819 1.0 3084625 TimTec1_004554 Nc1nc(nc2c3ccccc3oc(=O)c12)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O23 mock treatment 0.253 0.0105 0.57 0.5651 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 O24 mock treatment 0.242 -4.84E-4 -0.03 -0.026 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P01 compound treatment 0.441 0.199 10.67 10.6678 1.0 1465751 TimTec1_004555 O=C(Cc1ccccc1)Nc2ccc3oc(nc3c2)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P02 compound treatment 0.253 0.0105 0.57 0.5651 1.0 1350858 TimTec1_004556 Cc1cccc(C)c1N2CCc3cn[nH]c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P03 compound treatment 0.309 0.0665 3.57 3.5744 1.0 1593678 TimTec1_004557 COc1ccc(CCC(O)C2(O)CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P04 compound treatment 0.438 0.196 10.51 10.5066 1.0 1664967 TimTec1_004558 Clc1ccc(NC(=O)CC2SCCNC2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P05 compound treatment 0.481 0.239 12.82 12.8174 1.0 1438867 TimTec1_004559 O=C1N(CC2CCCO2)C(=O)c3cc(ccc13)c4nc5ccccc5c(=O)o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P06 compound treatment 0.256 0.0135 0.73 0.7263 1.0 1740022 TimTec1_004560 CC1CN(Cn2nc(c3ccccc3)n(CC=C)c2=S)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P07 compound treatment 0.37 0.128 6.85 6.8525 1.0 1430817 TimTec1_004561 O=C(CSCc1ccccc1)Nc2nnc(Cc3ccccc3)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P08 compound treatment 0.245 0.00252 0.14 0.1352 1.0 1573254 TimTec1_004562 CC(CN1CCNCC1)(NS(=O)(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P09 compound treatment 0.236 -0.00648 -0.35 -0.3484 -1.0 1431707 TimTec1_004563 COc1cc2C(CC(=O)Nc3ccccc3)C(=O)N(N=C(C)c2cc1OC)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P10 compound treatment 0.264 0.0215 1.16 1.1562 1.0 1386480 TimTec1_004564 CC(C)CNC(=O)c1cccc(NC(=O)CC(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P11 compound treatment 0.235 -0.00748 -0.4 -0.4022 -1.0 3212897 TimTec1_004565 C=CC/N=C(\SCc1ccccc1)/N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P12 compound treatment 0.451 0.209 11.21 11.2052 1.0 1213970 TimTec1_004566 CC(=O)Oc1coc2ccc3c(C)cc(=O)oc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P13 compound treatment 0.34 0.0975 5.24 5.2403 1.0 1578888 TimTec1_004567 Clc1ccc(cc1)C(NC(=O)c2ccccc2Cl)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P14 compound treatment 0.351 0.109 5.83 5.8314 1.0 1291706 TimTec1_004568 COC(=O)C1=C(C)NC(=C(C#N)C1c2cccnc2)S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P15 compound treatment 0.309 0.0665 3.57 3.5744 1.0 3212898 TimTec1_004569 CCSc1cccc2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P16 compound treatment 0.264 0.0215 1.16 1.1562 1.0 1230586 TimTec1_004570 CC(=O)Nc1cc2c(C)cc(=O)oc2c3C(=O)COc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P17 compound treatment 0.261 0.0185 1.0 0.995 1.0 3085776 TimTec1_004571 CCc1nnc(NC(=O)COC(=O)CSc2nc(cc(n2)c3ccccc3)c4ccccc4)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P18 compound treatment 0.455 0.213 11.42 11.4202 1.0 1673944 TimTec1_004572 Cc1nn2cc(nc2s1)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P19 compound treatment 0.228 -0.0145 -0.78 -0.7783 -1.0 3212899 TimTec1_004573 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P20 compound treatment 0.265 0.0225 1.21 1.21 1.0 3085777 TimTec1_004574 CCOC(=O)C1NCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P21 compound treatment 0.418 0.176 9.43 9.4319 1.0 1311348 TimTec1_004575 CCC(=O)Oc1ccc2c3CCCc3c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P22 compound treatment 0.235 -0.00748 -0.4 -0.4022 -1.0 1265079 TimTec1_004576 COc1ccc2nc(C)c3CC(C)Oc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P23 mock treatment 0.223 -0.0195 -1.05 -1.047 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2075 P24 mock treatment 0.243 5.16E-4 0.03 0.0277 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A01 compound treatment 0.353 0.104 5.57 5.5686 1.0 3212900 TimTec1_004577 Cc1n[nH]c(O)c1CCCOc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A02 compound treatment 0.246 -0.00338 -0.18 -0.1814 -1.0 3085778 TimTec1_004578 Cc1cc(Sc2ccccn2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A03 compound treatment 0.274 0.0246 1.32 1.3233 1.0 3212901 TimTec1_004579 [O-][n+]1onc2c(nnc(c3ccc(Cl)cc3)c12)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A04 compound treatment 0.226 -0.0234 -1.26 -1.2561 -1.0 3085779 TimTec1_004580 NC(=O)CSc1nc(N)cc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A05 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3212902 TimTec1_004581 Cc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCN(CC4)c5ccccc5)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A06 compound treatment 0.216 -0.0334 -1.79 -1.7935 -1.0 3085780 TimTec1_004582 COc1ccc(cc1OC)C2C(C(=O)NC(=C2C#N)O)[n+]3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A07 compound treatment 0.235 -0.0144 -0.77 -0.7725 -1.0 3211405 TimTec1_004583 CN1C(=O)CCN(C=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A08 compound treatment 0.226 -0.0234 -1.26 -1.2561 -1.0 1392481 TimTec1_004584 CCC(=O)Nc1c(C)c(Cl)c(C)nc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A09 compound treatment 0.281 0.0316 1.7 1.6995 1.0 3211202 TimTec1_004585 CC(=O)NC1C(=O)NC(=NC1=O)SCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A10 compound treatment 0.231 -0.0184 -0.99 -0.9874 -1.0 1665015 TimTec1_004586 OC1=C(C(=O)c2ccccc2)C3(OC1=O)C(=O)NC(=O)NC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A11 compound treatment 0.323 0.0736 3.96 3.9565 1.0 1224645 TimTec1_004587 COc1ccc(NC(=S)N(CC2CCCO2)CC3CCC=CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A12 compound treatment 0.217 -0.0324 -1.74 -1.7398 -1.0 1534543 TimTec1_004588 Cc1nc(C(=O)N)c(N)n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A13 compound treatment 0.252 0.00262 0.14 0.1411 1.0 3211203 TimTec1_004589 OC(=O)C1CCCCC1C(=O)Nc2ccc3[nH]c(=S)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A14 compound treatment 0.246 -0.00338 -0.18 -0.1814 -1.0 1303334 TimTec1_004590 CCC1(C)OC(=O)N(CCc2c(C)[nH]c3ccccc23)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A15 compound treatment 0.244 -0.00538 -0.29 -0.2888 -1.0 1738265 TimTec1_004591 CC1(C)CC(CC(C)(C)N1)N2C(=O)c3ccccc3C2(O)Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A16 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 1544216 TimTec1_004592 O=C1Nc2nonc2NC(=C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A17 compound treatment 0.267 0.0176 0.95 0.9471 1.0 1580828 TimTec1_004593 OCC1COC(=O)N1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A18 compound treatment 0.274 0.0246 1.32 1.3233 1.0 3211204 TimTec1_004594 CN1CCN(CC1)n/2c(cs\c2=N/c3ccccc3)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A19 compound treatment 0.54 0.291 15.62 15.6176 1.0 3085781 TimTec1_004595 CCCn1c2ccccc2c3nnc(SCCNS(=O)(=O)c4ccccc4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A20 compound treatment 0.242 -0.00738 -0.4 -0.3963 -1.0 1295244 TimTec1_004596 COc1ccc(cc1OC)S(=O)(=O)NCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A21 compound treatment 0.28 0.0306 1.65 1.6457 1.0 1339032 TimTec1_004597 O=S1(=O)N=C(Oc2ccccc2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A22 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3211205 TimTec1_004598 COc1ccc(cc1)n2c(=O)c3c4CC(OCc4sc3n5cnnc25)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A23 mock treatment 0.243 -0.00638 -0.34 -0.3426 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 A24 mock treatment 0.26 0.0106 0.57 0.571 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B01 compound treatment 0.29 0.0406 2.18 2.1831 1.0 1180956 TimTec1_004599 CC(=O)Nc1cccc(C(=O)Oc2cccc(C)c2)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B02 compound treatment 0.38 0.131 7.02 7.0195 1.0 3211206 TimTec1_004600 CC(C)OC(=O)COc1ccc2C(CC3(CC(C)(C)NC(=O)N3)Oc2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B03 compound treatment 0.41 0.161 8.63 8.6317 1.0 3085782 TimTec1_004601 O=S1(=O)N(Cc2ccccn2)c3cccc4cccc1c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B04 compound treatment 0.423 0.174 9.33 9.3302 1.0 3211207 TimTec1_004602 Cc1nn(c(N)c1c2ccc(Cl)cc2)c3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B05 compound treatment 0.398 0.149 7.99 7.9868 1.0 3085783 TimTec1_004603 OC1COC(NCCc2ccccc2)C(O)C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B06 compound treatment 0.294 0.0446 2.4 2.3981 1.0 1409204 TimTec1_004604 N(c1ccccc1)c2nc3nonc3nc2Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B07 compound treatment 0.258 0.00862 0.46 0.4635 1.0 3211208 TimTec1_004605 FC(F)(F)C1(N=C(Nc2c1c(=O)[nH]c(=O)n2c3ccccc3)c4ccncc4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B08 compound treatment 0.25 6.25E-4 0.03 0.0336 1.0 3085788 TimTec1_004606 CN1C2NCN(CCc3ccccc3)CC2C(=O)N(C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B09 compound treatment 0.286 0.0366 1.97 1.9682 1.0 3211209 TimTec1_004607 CCOc1ccc(Cn2nnc(n2)c3ccc(cc3)S(=O)(=O)C)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B10 compound treatment 0.438 0.189 10.14 10.1363 1.0 1264288 TimTec1_004608 CN(NC1=C(C)CN(C2CCCCC2)C1=O)c3cccc(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B11 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 3211210 TimTec1_004609 OCC1OC(C(O)C1O)n2ccc(O)nc2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B12 compound treatment 0.437 0.188 10.08 10.0826 1.0 1629862 TimTec1_004610 OC1=C(Cc2ccccc2)CN(Cc3ccccc3)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B13 compound treatment 0.518 0.269 14.44 14.4353 1.0 3211211 TimTec1_004611 CCCCc1ccc2nc3sc(cc3cc2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B14 compound treatment 0.26 0.0106 0.57 0.571 1.0 3085792 TimTec1_004612 CC1(C)CC(=O)OC(C1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B15 compound treatment 0.333 0.0836 4.49 4.4938 1.0 3211212 TimTec1_004613 CCCCS(=O)(=O)Nc1ccc(Cc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B16 compound treatment 0.262 0.0126 0.68 0.6784 1.0 3211213 TimTec1_004614 FC(F)(F)C(=O)Nc1ccccc1C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B17 compound treatment 0.263 0.0136 0.73 0.7322 1.0 3085794 TimTec1_004615 CC(C)Nc1nc(nc(n1)n2ccnc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B18 compound treatment 0.266 0.0166 0.89 0.8934 1.0 3085836 TimTec1_004616 O=CN1CCN(CC1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B19 compound treatment 0.254 0.00462 0.25 0.2485 1.0 3085838 TimTec1_004617 N(c1cccc2ccccc12)c3nc(nc(n3)n4ccnc4)n5ccnc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B20 compound treatment 0.357 0.108 5.78 5.7835 1.0 1599768 TimTec1_004618 COC(=O)C1C(c2cc(OC)c(OC)cc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B21 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3085840 TimTec1_004619 CC(C)(O)c1nnn(Cc2ccccc2)c1C(C)(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B22 compound treatment 0.376 0.127 6.8 6.8046 1.0 1176863 TimTec1_004620 Cc1ncsc1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B23 mock treatment 0.231 -0.0184 -0.99 -0.9874 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 B24 mock treatment 0.226 -0.0234 -1.26 -1.2561 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C01 compound treatment 0.236 -0.0134 -0.72 -0.7187 -1.0 3085842 TimTec1_004621 O=C(N/C(=C(\Sc1ccccn1)/c2ccccc2)/C(=O)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C02 compound treatment 0.458 0.209 11.21 11.2111 1.0 3211214 TimTec1_004622 N#Cc1ccc(CSc2ncccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C03 compound treatment 0.38 0.131 7.02 7.0195 1.0 1239016 TimTec1_004623 COc1ccc(C(=O)Nc2ccncc2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C04 compound treatment 0.347 0.0976 5.25 5.2462 1.0 1306638 TimTec1_004624 COc1ccc(cc1OC)C(=O)CSC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C05 compound treatment 0.236 -0.0134 -0.72 -0.7187 -1.0 3085845 TimTec1_004625 CN1C(OC(=O)C)C(OC(=O)C)N(C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C06 compound treatment 0.242 -0.00738 -0.4 -0.3963 -1.0 1689037 TimTec1_004626 CC(=O)Nc1ccc(cc1)C2N3CCCN23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C07 compound treatment 0.262 0.0126 0.68 0.6784 1.0 1384622 TimTec1_004627 C=CCN1C(=O)CCNc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C08 compound treatment 0.241 -0.00838 -0.45 -0.4501 -1.0 1104469 TimTec1_004628 Cc1cc(Cl)nc(Cl)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C09 compound treatment 0.298 0.0486 2.61 2.613 1.0 1540410 TimTec1_004629 Brc1ccc(o1)C(=O)NC2C3CC4CC(C3)CC2C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C10 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3085848 TimTec1_004630 C1CCN2C(C3N4CCCCN34)N2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C11 compound treatment 0.312 0.0626 3.37 3.3653 1.0 1554188 TimTec1_004631 CCOC(=O)C1(CCN(CCOc2ccccc2)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C12 compound treatment 0.362 0.113 6.05 6.0522 1.0 1287126 TimTec1_004632 O=S(Cc1ccccc1)c2cc(Oc3ccccc3)ccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C13 compound treatment 0.344 0.0946 5.08 5.0849 1.0 3211215 TimTec1_004633 O=C/1N2C(=C\C1=C/N3CCCCC3)C(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C14 compound treatment 0.288 0.0386 2.08 2.0756 1.0 1182870 TimTec1_004634 CCCc1cc2c3ccccc3oc(=O)c2c(NC(=O)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C15 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 1129282 TimTec1_004635 OC(=O)C1CC(=O)CCC1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C16 compound treatment 0.254 0.00462 0.25 0.2485 1.0 1342925 TimTec1_004636 COc1nc(Cl)nc(n1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C17 compound treatment 0.314 0.0646 3.47 3.4728 1.0 3211216 TimTec1_004637 OC(=O)c1ccc(/C=C/2\C(=O)NC(=O)N(C3CCCCC3)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C18 compound treatment 0.305 0.0556 2.99 2.9892 1.0 1658196 TimTec1_004638 CCCCc1c(C)nc2ccc(Br)cc2c1SCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C19 compound treatment 0.284 0.0346 1.86 1.8607 1.0 1175416 TimTec1_004639 CC(=O)NC(C)(C)COc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C20 compound treatment 0.256 0.00662 0.36 0.356 1.0 1184099 TimTec1_004640 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C21 compound treatment 0.26 0.0106 0.57 0.571 1.0 3085855 TimTec1_004641 CC1=CC(C)(C)NC(=S)N1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C22 compound treatment 0.259 0.00962 0.52 0.5172 1.0 1171271 TimTec1_004642 O=C(NN1C(=O)c2ccccc2NC31CCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C23 mock treatment 0.258 0.00862 0.46 0.4635 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 C24 mock treatment 0.25 6.25E-4 0.03 0.0336 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D01 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 1550109 TimTec1_004643 Cc1oc(C)c(C(=O)O)c1CN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D02 compound treatment 0.26 0.0106 0.57 0.571 1.0 3085895 TimTec1_004644 Clc1ccc2oc3c(=O)oc(nc3c2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D03 compound treatment 0.251 0.00162 0.09 0.0873 1.0 3211406 TimTec1_004645 O=C(NC(=O)c1ccccc1)OC2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D04 compound treatment 0.25 6.25E-4 0.03 0.0336 1.0 3211407 TimTec1_004646 OC(=O)CC(NC(=O)C1(CC2CC3CC(C2)C1)C3)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D05 compound treatment 0.235 -0.0144 -0.77 -0.7725 -1.0 3085898 TimTec1_004647 CN(C1CC(C)(C)NC(C)(C)C1)C(=O)c2ccccc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D06 compound treatment 0.245 -0.00438 -0.24 -0.2351 -1.0 1913187 TimTec1_004648 CSc1sc(SC)c(C[n+]2ccccc2)c1C[n+]3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D07 compound treatment 0.264 0.0146 0.79 0.7859 1.0 3085900 TimTec1_004649 Cc1cc(NC(=O)NC(=O)c2cccs2)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D08 compound treatment 0.251 0.00162 0.09 0.0873 1.0 1392952 TimTec1_004650 COc1ccc(cc1)N2CC(CC2=O)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D09 compound treatment 0.24 -0.00938 -0.5 -0.5038 -1.0 3211408 TimTec1_004651 Cc1cn(CC(=O)NCCN)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D10 compound treatment 0.266 0.0166 0.89 0.8934 1.0 1692385 TimTec1_004652 CN(Nc1ccccc1)C2=C(CN(C3CCCCC3)C2=O)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D11 compound treatment 0.251 0.00162 0.09 0.0873 1.0 3211409 TimTec1_004653 Cc1cc(=O)[nH]c2nn(c(O)c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D12 compound treatment 0.242 -0.00738 -0.4 -0.3963 -1.0 3085903 TimTec1_004654 CCOC(=O)C1=C(O)CN(C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D13 compound treatment 0.265 0.0156 0.84 0.8397 1.0 3211410 TimTec1_004655 Cc1nn(C(=O)c2ccc(F)cc2)c(N)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D14 compound treatment 0.274 0.0246 1.32 1.3233 1.0 3085905 TimTec1_004656 CCn1ncc(Cl)c(Cl)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D15 compound treatment 0.38 0.131 7.02 7.0195 1.0 3211411 TimTec1_004657 COc1cc(C)c(cc1C(C)C)S(=O)(=O)Nc2ccc3nc(C)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D16 compound treatment 0.361 0.112 6.0 5.9985 1.0 1577125 TimTec1_004658 CCOC(=O)CCCN1C(CCc2ccccc12)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D17 compound treatment 0.266 0.0166 0.89 0.8934 1.0 3211412 TimTec1_004659 C1CC1Nc2nc(nc(n2)n3ccnc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D18 compound treatment 0.255 0.00562 0.3 0.3023 1.0 1034819 TimTec1_004660 CC(O)(c1ccccc1)C(C)(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D19 compound treatment 0.269 0.0196 1.05 1.0546 1.0 3211413 TimTec1_004661 O=S(=O)(Cc1ccccc1C#N)c2nc3cccnc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D20 compound treatment 0.26 0.0106 0.57 0.571 1.0 3211414 TimTec1_004662 Oc1nc(Oc2cccc(c2)C(F)(F)F)cc(Oc3cccc(c3)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D21 compound treatment 0.499 0.25 13.41 13.4143 1.0 3085910 TimTec1_004663 CN(C(=O)CSc1nc(C)cc2COC(=O)c21)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D22 compound treatment 0.373 0.124 6.64 6.6433 1.0 3085911 TimTec1_004664 Cc1cc(=O)n(CNC(=O)c2ccco2)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D23 mock treatment 0.255 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 D24 mock treatment 0.241 -0.00838 -0.45 -0.4501 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E01 compound treatment 0.522 0.273 14.65 14.6503 1.0 3211415 TimTec1_004665 O/N=C(/C#N)\c1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E02 compound treatment 0.431 0.182 9.76 9.7601 1.0 1640993 TimTec1_004666 CCOc1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccccc5C4=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E03 compound treatment 0.485 0.236 12.66 12.662 1.0 1162299 TimTec1_004667 COc1ccc(cc1)c2nnc(NC(=O)CC(C)C)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E04 compound treatment 0.507 0.258 13.84 13.8442 1.0 3085914 TimTec1_004668 Cc1nnc(SCC(=O)c2ccc(Cl)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E05 compound treatment 0.404 0.155 8.31 8.3092 1.0 3211416 TimTec1_004669 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E06 compound treatment 0.341 0.0916 4.92 4.9237 1.0 3211417 TimTec1_004670 OC(=O)CSc1nnc(c2ccccc2Br)n1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E07 compound treatment 0.265 0.0156 0.84 0.8397 1.0 1165665 TimTec1_004671 CC(C)N1C(=O)CCNc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E08 compound treatment 0.349 0.0996 5.35 5.3536 1.0 3085950 TimTec1_004672 Clc1ccc(SCc2[nH]n(c3nc4ccccc4s3)c(=O)c2/C=N/Cc5ccco5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E09 compound treatment 0.246 -0.00338 -0.18 -0.1814 -1.0 1675123 TimTec1_004673 COc1cc(CNC(=O)C2CCCC2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E10 compound treatment 0.26 0.0106 0.57 0.571 1.0 1569434 TimTec1_004674 CCn1c(=N)n(CC(=O)c2ccc(Br)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E11 compound treatment 0.258 0.00862 0.46 0.4635 1.0 3085953 TimTec1_004675 CC(C)(C)Nc1nc(=O)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E12 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 3211418 TimTec1_004676 C[C@H]1C[C@H](C2C(=NNC2=O)C)N(N1c3ccccc3)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E13 compound treatment 0.375 0.126 6.75 6.7508 1.0 1364377 TimTec1_004677 CN(Cc1ccccc1)Cc2c(O)ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E14 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3211419 TimTec1_004678 O=C(C1CCCCC1)n2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E15 compound treatment 0.3 0.0506 2.72 2.7205 1.0 3085956 TimTec1_004679 Cn1c(=O)c(C#N)c(c2ccccc2)n3cnnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E16 compound treatment 0.285 0.0356 1.91 1.9144 1.0 3085958 TimTec1_004680 C=CCNC(=O)C#Cc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E17 compound treatment 0.362 0.113 6.05 6.0522 1.0 3211420 TimTec1_004681 CCOC(=O)n1ncc(C#N)c1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E18 compound treatment 0.252 0.00262 0.14 0.1411 1.0 1935336 TimTec1_004682 CC(=O)OC1CC(C)(C)N(O)C(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E19 compound treatment 0.318 0.0686 3.69 3.6878 1.0 1210397 TimTec1_004683 CC1CN(OC(O1)c2cccc(O)c2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E20 compound treatment 0.309 0.0596 3.2 3.2041 1.0 3085961 TimTec1_004684 CCN(N)c1nc(Cl)cc(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E21 compound treatment 0.283 0.0336 1.81 1.8069 1.0 1723779 TimTec1_004685 COC(C(=O)Nc1ccc(Cl)cn1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E22 compound treatment 0.272 0.0226 1.22 1.2158 1.0 1263589 TimTec1_004686 NCC1(CC2CC3C1)CC(CN)(C2)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E23 mock treatment 0.265 0.0156 0.84 0.8397 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 E24 mock treatment 0.251 0.00162 0.09 0.0873 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F01 compound treatment 0.292 0.0426 2.29 2.2906 1.0 1717073 TimTec1_004687 COc1ccc(CC2C(=O)NC(=O)N(C2=O)c3cccc(Cl)c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F02 compound treatment 0.26 0.0106 0.57 0.571 1.0 3085964 TimTec1_004688 S=C(NC(c1ccccc1)c2ccccc2)Nc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F03 compound treatment 0.29 0.0406 2.18 2.1831 1.0 1738878 TimTec1_004689 CC(C)(C)c1nnc(Nc2ccc3OCOc3c2)n(N)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F04 compound treatment 0.256 0.00662 0.36 0.356 1.0 3085966 TimTec1_004690 OCc1ccccc1NC(=S)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F05 compound treatment 0.325 0.0756 4.06 4.0639 1.0 3211421 TimTec1_004691 FC(F)(F)c1cccc(c1)N2C(Nc3ccccc3C2=O)c4ccc5cccnc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F06 compound treatment 0.259 0.00962 0.52 0.5172 1.0 1429088 TimTec1_004692 CC(C)CCOc1ccc(cc1)C2(C)NC(=O)N(CN3CCOCC3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F07 compound treatment 0.27 0.0206 1.11 1.1083 1.0 3085968 TimTec1_004693 CCC(=O)Oc1ccc(cc1OC)C2CC(=O)c3c(N2)ccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F08 compound treatment 0.301 0.0516 2.77 2.7742 1.0 3085970 TimTec1_004694 OC(=O)c1cc(on1)c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F09 compound treatment 0.251 0.00162 0.09 0.0873 1.0 3211422 TimTec1_004695 COc1ccc(cc1)C(=O)c2[nH]c(cc2c3ccccc3)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F10 compound treatment 0.468 0.219 11.75 11.7485 1.0 1353733 TimTec1_004696 CCOC(=O)C1=C(CN(C1)C(=O)c2ccccc2)NN(C)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F11 compound treatment 0.286 0.0366 1.97 1.9682 1.0 3085972 TimTec1_004697 Oc1[nH]nc2nc(cc(c12)C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F12 compound treatment 0.254 0.00462 0.25 0.2485 1.0 3211423 TimTec1_004698 CN(C1=C(C)CN(C2CCCCC2)C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F13 compound treatment 0.356 0.107 5.73 5.7298 1.0 3211424 TimTec1_004699 Cc1nn(C(=O)COc2ccc(Cl)cc2Cl)c(N)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F14 compound treatment 0.273 0.0236 1.27 1.2696 1.0 3086016 TimTec1_004700 COc1ccc(cc1)N(C(C)C2C(C)(C)C2(C)C)C(=O)Nc3ccccc3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F15 compound treatment 0.239 -0.0104 -0.56 -0.5575 -1.0 3211510 TimTec1_004701 OC1(N(C2CC2)C(=O)c3ccccc31)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F16 compound treatment 0.262 0.0126 0.68 0.6784 1.0 1249129 TimTec1_004702 CCC1(COCc2ccccc2)CCC(O1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F17 compound treatment 0.352 0.103 5.51 5.5149 1.0 3211511 TimTec1_004703 CCN(Cc1ccccc1)C(=O)c2sc3nc(C)cc(C)c3c2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F18 compound treatment 0.329 0.0796 4.28 4.2789 1.0 3086019 TimTec1_004704 COc1ccc2/C(=N/N)/CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F19 compound treatment 0.531 0.282 15.13 15.1339 1.0 3211512 TimTec1_004705 Nc1nnc(s1)c2ccc(Cn3c(nc4ccccc34)c5cncs5)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F20 compound treatment 0.264 0.0146 0.79 0.7859 1.0 3211513 TimTec1_004706 CS(=O)(=O)c1nc(Oc2cccc(c2)C(F)(F)F)cc(Oc3cccc(c3)C(F)(F)F)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F21 compound treatment 0.276 0.0266 1.43 1.4308 1.0 1223782 TimTec1_004707 OCC1CCCCN1C(=S)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F22 compound treatment 0.41 0.161 8.63 8.6317 1.0 3211514 TimTec1_004708 COc1ccc2C(=O)/C(=N\O)/CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F23 mock treatment 0.257 0.00762 0.41 0.4098 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 F24 mock treatment 0.226 -0.0234 -1.26 -1.2561 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G01 compound treatment 0.32 0.0706 3.8 3.7952 1.0 1356880 TimTec1_004709 OC(=O)c1cc(nc2ccc(Br)cc12)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G02 compound treatment 0.488 0.239 12.82 12.8232 1.0 3211515 TimTec1_004710 Brc1ccc(cc1)C2=CC(=O)OC(O2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G03 compound treatment 0.241 -0.00838 -0.45 -0.4501 -1.0 2106889 TimTec1_004711 Nc1nc(Cl)cc(Oc2ccc(Cl)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G04 compound treatment 0.239 -0.0104 -0.56 -0.5575 -1.0 1151915 TimTec1_004712 CN1C(=O)C(Cc2c(C)[nH]c3ccccc23)C(=O)N(C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G05 compound treatment 0.28 0.0306 1.65 1.6457 1.0 1509629 TimTec1_004713 Cn1c(SCC(=O)c2ccc3CCCCc3c2)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G06 compound treatment 0.26 0.0106 0.57 0.571 1.0 1368472 TimTec1_004714 Cc1nonc1NC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G07 compound treatment 0.278 0.0286 1.54 1.5382 1.0 1733999 TimTec1_004715 S=C1CCN(Cc2ccccc2)c3ccccc3N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G08 compound treatment 0.244 -0.00538 -0.29 -0.2888 -1.0 1463893 TimTec1_004716 CN1CCN(CC1)C(=O)c2c(C)oc3cc4c(C(=O)N5CCN(C)CC5)c(C)oc4cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G09 compound treatment 0.261 0.0116 0.62 0.6247 1.0 3086027 TimTec1_004717 CCOc1ccc2nc(NC(NC(=O)CC)(C(F)(F)F)C(F)(F)F)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G10 compound treatment 0.254 0.00462 0.25 0.2485 1.0 3211516 TimTec1_004718 Fc1ccc(cc1)c2n[nH]cc2C=C3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G11 compound treatment 0.385 0.136 7.29 7.2882 1.0 1735827 TimTec1_004719 CCN(CC)C(=S)Nc1ccc2oc(nc2c1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G12 compound treatment 0.278 0.0286 1.54 1.5382 1.0 3211517 TimTec1_004720 CC1(NN(C(=S)N1)c2ccccc2)C3(C)COCOC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G13 compound treatment 0.269 0.0196 1.05 1.0546 1.0 3086031 TimTec1_004721 CCOc1ccccc1C(=O)n2cc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G14 compound treatment 0.361 0.112 6.0 5.9985 1.0 1425223 TimTec1_004722 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cc(C)on4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G15 compound treatment 0.481 0.232 12.45 12.447 1.0 1383059 TimTec1_004723 CC1CCN(CC1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G16 compound treatment 0.251 0.00162 0.09 0.0873 1.0 1606397 TimTec1_004724 O=S(=O)(NCC1(CC2CC3CC(C2)C1)C3)c4cccc5nsnc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G17 compound treatment 0.333 0.0836 4.49 4.4938 1.0 3211518 TimTec1_004725 COc1ccc(CCN2C(CC(=O)N)C(=O)N(C2=S)c3cccc(c3)C(F)(F)F)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G18 compound treatment 0.397 0.148 7.93 7.9331 1.0 3086077 TimTec1_004726 Clc1cccc(c1)C2CC(=O)C(=CNC3CCCC3)C(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G19 compound treatment 0.483 0.234 12.55 12.5545 1.0 1327319 TimTec1_004727 COc1ccc(cc1OC)C2OC(COc3ccccc3)CN(O2)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G20 compound treatment 0.26 0.0106 0.57 0.571 1.0 1653659 TimTec1_004728 Clc1ccc(cc1)c2csc3c4ncnc4ncn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G21 compound treatment 0.332 0.0826 4.44 4.4401 1.0 3211519 TimTec1_004729 Cn1c(/C=C/C(=O)O)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G22 compound treatment 0.278 0.0286 1.54 1.5382 1.0 3211520 TimTec1_004730 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G23 mock treatment 0.255 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 G24 mock treatment 0.241 -0.00838 -0.45 -0.4501 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H01 compound treatment 0.278 0.0286 1.54 1.5382 1.0 1710338 TimTec1_004731 Cn1c(CS(=O)(=O)c2ccccc2)c(C#N)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H02 compound treatment 0.434 0.185 9.92 9.9214 1.0 3211521 TimTec1_004732 Clc1ccc(CS(=O)(=O)c2nc3cccnc3[nH]2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H03 compound treatment 0.397 0.148 7.93 7.9331 1.0 3086082 TimTec1_004733 Cc1[nH]c2ccccc2c1CCN3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H04 compound treatment 0.276 0.0266 1.43 1.4308 1.0 3211522 TimTec1_004734 O=C(NC(=O)c1cccs1)OC[C@@H]2CCCN3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H05 compound treatment 0.333 0.0836 4.49 4.4938 1.0 3086084 TimTec1_004735 OC(=O)CCc1ccc(c2ccccc2)n1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H06 compound treatment 0.251 0.00162 0.09 0.0873 1.0 3211523 TimTec1_004736 OC1(CC(=NN1C(=O)c2cccnc2)C(F)(F)F)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H07 compound treatment 0.358 0.109 5.84 5.8373 1.0 3211524 TimTec1_004737 Fc1cccc(c1)C(=O)NC(=O)Nc2nc(cc(n2)C(F)(F)F)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H08 compound treatment 0.491 0.242 12.98 12.9844 1.0 3086087 TimTec1_004738 Fc1ccccc1CCNc2c3CCCCc3nc4ncnn24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H09 compound treatment 0.383 0.134 7.18 7.1807 1.0 3086089 TimTec1_004739 Cc1ccoc1C(=O)NCCN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H10 compound treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1653767 TimTec1_004740 CCOC(=O)C1=C(NC(C)C)C(=O)N(C1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H11 compound treatment 0.259 0.00962 0.52 0.5172 1.0 3211525 TimTec1_004741 CC1Cc2nn(c(c2C(=O)C1C)c3cccnc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H12 compound treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1563400 TimTec1_004742 CN1CC(=C(NC2CCCCC2)C1=O)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H13 compound treatment 0.292 0.0426 2.29 2.2906 1.0 3211526 TimTec1_004743 O=C1N(Cc2cccnc2)C(NCc3cccnc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H14 compound treatment 0.252 0.00262 0.14 0.1411 1.0 3086093 TimTec1_004744 Cc1cc(C)[n+]2c(csc2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H15 compound treatment 0.31 0.0606 3.26 3.2579 1.0 1868951 TimTec1_004745 CCOC(=O)c1c(C)cc(C)[nH]c1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H16 compound treatment 0.264 0.0146 0.79 0.7859 1.0 1285461 TimTec1_004746 COc1cc(C(=O)CN2C(=O)c3ccccc3C2=O)c(OC)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H17 compound treatment 0.246 -0.00338 -0.18 -0.1814 -1.0 3086156 TimTec1_004747 CCOc1ccc(CCNC(=O)Cc2nnc[nH]2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H18 compound treatment 0.244 -0.00538 -0.29 -0.2888 -1.0 1091806 TimTec1_004748 CCC1C[N+]2(C)CCc3cc(OC)c(OC)cc3C2CC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H19 compound treatment 0.289 0.0396 2.13 2.1294 1.0 3086159 TimTec1_004749 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H20 compound treatment 0.267 0.0176 0.95 0.9471 1.0 3211527 TimTec1_004750 CS(=O)(=O)c1ccc(C(=O)O)c(O)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H21 compound treatment 0.288 0.0386 2.08 2.0756 1.0 3211528 TimTec1_004751 CC(C)(C)NC(=O)Cn1nnc(n1)c2ccc(cc2)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H22 compound treatment 0.259 0.00962 0.52 0.5172 1.0 1019007 TimTec1_004752 COc1ncnc2[nH]cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H23 mock treatment 0.258 0.00862 0.46 0.4635 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 H24 mock treatment 0.242 -0.00738 -0.4 -0.3963 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I01 compound treatment 0.23 -0.0194 -1.04 -1.0412 -1.0 1573225 TimTec1_004753 O=C(N1CCOCC1)c2ccccc2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I02 compound treatment 0.501 0.252 13.52 13.5218 1.0 1382795 TimTec1_004754 O=C(CSc1ccccn1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I03 compound treatment 0.256 0.00662 0.36 0.356 1.0 1128047 TimTec1_004755 O=C(Oc1cccc2cccnc12)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I04 compound treatment 0.286 0.0366 1.97 1.9682 1.0 1498538 TimTec1_004756 CC(NC(=O)c1nc[nH]n1)c2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I05 compound treatment 0.244 -0.00538 -0.29 -0.2888 -1.0 1694793 TimTec1_004757 NC(=O)N1CCC(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I06 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 1660022 TimTec1_004758 CC12CCCCC2N(CC(=O)N)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I07 compound treatment 0.398 0.149 7.99 7.9868 1.0 1335680 TimTec1_004759 Cc1nc2ccccn2c1c3csc(Nc4ccc(C)cc4C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I08 compound treatment 0.303 0.0536 2.88 2.8817 1.0 1266099 TimTec1_004760 Clc1ccc2oc(=O)n(C(=O)Oc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I09 compound treatment 0.254 0.00462 0.25 0.2485 1.0 3211606 TimTec1_004761 OC(=O)C(Cc1ccccc1)P(=O)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I10 compound treatment 0.317 0.0676 3.63 3.634 1.0 3086166 TimTec1_004762 COc1ccc(c2nnc3ccc(Cl)nn23)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I11 compound treatment 0.342 0.0926 4.98 4.9775 1.0 1268857 TimTec1_004763 COc1ccc(c2csc(n2)C3COc4ccccc4O3)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I12 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 1370075 TimTec1_004764 CN(C(=O)Cn1nnnc1N)C2(CCCCC2)C(=O)Nc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I13 compound treatment 0.284 0.0346 1.86 1.8607 1.0 1698831 TimTec1_004765 O=c1nc(Nc2ccccc2)[nH]c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I14 compound treatment 0.491 0.242 12.98 12.9844 1.0 3211607 TimTec1_004766 Cc1ccc(/C(=C/C2=NCCNC(C2)c3ccccc3)/O)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I15 compound treatment 0.252 0.00262 0.14 0.1411 1.0 1314790 TimTec1_004767 COC(C(=O)NCc1cccnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I16 compound treatment 0.282 0.0326 1.75 1.7532 1.0 3211608 TimTec1_004768 CCCC/1=NN(C(=O)\C1=C/N)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I17 compound treatment 0.511 0.262 14.06 14.0592 1.0 1621835 TimTec1_004769 CCN(CC)c1ccc2c(=O)[nH][nH]c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I18 compound treatment 0.477 0.228 12.23 12.2321 1.0 1274514 TimTec1_004770 Fc1ccc(cc1)c2cn3nc4CCCCc4nc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I19 compound treatment 0.409 0.16 8.58 8.5779 1.0 1017274 TimTec1_004771 CCOC(=O)c1cnc2ccc(OC)cc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I20 compound treatment 0.26 0.0106 0.57 0.571 1.0 1179846 TimTec1_004772 O=C(c1ccccc1)c2ccc(cc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I21 compound treatment 0.27 0.0206 1.11 1.1083 1.0 1674029 TimTec1_004773 CCCCC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I22 compound treatment 0.444 0.195 10.46 10.4587 1.0 1703643 TimTec1_004774 COCc1cc(C)nc2sc3C(=O)NC(Nc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I23 mock treatment 0.267 0.0176 0.95 0.9471 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 I24 mock treatment 0.241 -0.00838 -0.45 -0.4501 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J01 compound treatment 0.49 0.241 12.93 12.9307 1.0 1596975 TimTec1_004775 COc1ccc(cc1)C(=O)n2c(=S)nc3cc(C)ccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J02 compound treatment 0.366 0.117 6.27 6.2672 1.0 3211609 TimTec1_004776 Cc1ccc(cc1)C(=O)OC2CC(OC2CO)n3ccc(NC(=O)c4ccccc4)nc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J03 compound treatment 0.243 -0.00638 -0.34 -0.3426 -1.0 1526337 TimTec1_004777 COc1ccc(cc1)C2=C(CC(=O)O)C(=O)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J04 compound treatment 0.294 0.0446 2.4 2.3981 1.0 3211610 TimTec1_004778 Cc1ccc(cc1)C(=O)NC(=O)OC[C@@H]2CCCN3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J05 compound treatment 0.393 0.144 7.72 7.7181 1.0 1520302 TimTec1_004779 C(Cn1c(COc2ccccc2)nc3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J06 compound treatment 0.254 0.00462 0.25 0.2485 1.0 1554201 TimTec1_004780 Cc1ccc(cc1)N(C(=O)c2ccccn2)C3(CCCCC3)C(=O)Nc4c(C)cccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J07 compound treatment 0.274 0.0246 1.32 1.3233 1.0 3211611 TimTec1_004781 Cc1ccc(cc1C)n2nc(C(=O)O)c(/C=C/c3ccc(Cl)cc3Cl)c(C#N)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J08 compound treatment 0.251 0.00162 0.09 0.0873 1.0 3086243 TimTec1_004782 Clc1ccc(NCc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J09 compound treatment 0.462 0.213 11.43 11.426 1.0 3211612 TimTec1_004783 C(c1cn(Cc2ccccc2)nn1)n3nnc(n3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J10 compound treatment 0.252 0.00262 0.14 0.1411 1.0 1008095 TimTec1_004784 NC(=S)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J11 compound treatment 0.253 0.00362 0.19 0.1948 1.0 3211613 TimTec1_004785 OC(=O)CCN1CCn2c1nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J12 compound treatment 0.447 0.198 10.62 10.62 1.0 1404920 TimTec1_004786 CCOC(=O)C1=C(NC2CCCCC2)C(=O)N(C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J13 compound treatment 0.265 0.0156 0.84 0.8397 1.0 3211614 TimTec1_004787 CCOc1ccc(CC(=O)C2C(=O)CC(C)(C)CC2=O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J14 compound treatment 0.256 0.00662 0.36 0.356 1.0 1418487 TimTec1_004788 CCOC(=O)c1nccnc1N(C(=O)c2ccc(C)cc2)C(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J15 compound treatment 0.373 0.124 6.64 6.6433 1.0 3086247 TimTec1_004789 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC4CCCC4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J16 compound treatment 0.254 0.00462 0.25 0.2485 1.0 3211615 TimTec1_004790 CSC(=S)NCc1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J17 compound treatment 0.278 0.0286 1.54 1.5382 1.0 3211616 TimTec1_004791 CCC1(CN2CC3(CC)CN(C1)C2c4c(C)[nH]c5ccccc45)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J18 compound treatment 0.406 0.157 8.42 8.4167 1.0 1118951 TimTec1_004792 CC1=CC(=O)CN(C1)S(=O)(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J19 compound treatment 0.264 0.0146 0.79 0.7859 1.0 3086250 TimTec1_004793 CS(=O)(=O)NCc1ccc(cc1)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J20 compound treatment 0.285 0.0356 1.91 1.9144 1.0 3211617 TimTec1_004794 Fc1cccc2ncnc(OCc3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J21 compound treatment 0.26 0.0106 0.57 0.571 1.0 3211618 TimTec1_004795 COc1ccccc1NC(=O)C(F)(F)C(=O)Nc2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J22 compound treatment 0.28 0.0306 1.65 1.6457 1.0 1295066 TimTec1_004796 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J23 mock treatment 0.254 0.00462 0.25 0.2485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 J24 mock treatment 0.24 -0.00938 -0.5 -0.5038 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K01 compound treatment 0.335 0.0856 4.6 4.6013 1.0 3211619 TimTec1_004797 Cc1ccc(NC(=O)c2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K02 compound treatment 0.269 0.0196 1.05 1.0546 1.0 1736764 TimTec1_004798 CC(C)Cc1nc(C#N)c(N)c(c1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K03 compound treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1338385 TimTec1_004799 CN(C)N=Nc1ccc(cc1)S(=O)(=O)N(C(=O)C)C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K04 compound treatment 0.245 -0.00438 -0.24 -0.2351 -1.0 1523329 TimTec1_004800 COc1cc(ccc1O)C2N(Cc3ccccc3)CCCN2Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K05 compound treatment 0.254 0.00462 0.25 0.2485 1.0 1577188 TimTec1_004801 CC1CC(=O)Nc2ccccc2N1C=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K06 compound treatment 0.237 -0.0124 -0.67 -0.665 -1.0 1555913 TimTec1_004802 Cc1ccc(NC(=O)C2(CCCCC2)NC(=O)c3ccc(cc3)n4cnnn4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K07 compound treatment 0.263 0.0136 0.73 0.7322 1.0 3211620 TimTec1_004803 Cc1nc2ccccn2c1c3csc(Nc4ccc(Br)cc4Br)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K08 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 3086325 TimTec1_004804 OCC1(CCCCC1)C2=NOC(O)(C2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K09 compound treatment 0.251 0.00162 0.09 0.0873 1.0 1021311 TimTec1_004805 C[N+]1(CC[N+]2(C)CCCCC2)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K10 compound treatment 0.25 6.25E-4 0.03 0.0336 1.0 1399338 TimTec1_004806 OC(C1CN2CCC1CC2)(c3cccc(Cl)c3)c4cccc(Cl)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K11 compound treatment 0.549 0.3 16.1 16.1012 1.0 3086328 TimTec1_004807 Cc1ccc(CC2SC(=NC2=O)N3CCN(CC3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K12 compound treatment 0.35 0.101 5.41 5.4074 1.0 1611430 TimTec1_004808 CC1CCc2nc3ccc4ccccc4c3c(c5ccc(O)c(O)c5)c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K13 compound treatment 0.261 0.0116 0.62 0.6247 1.0 1442519 TimTec1_004809 CC(=O)OC1CCC(C(OC(=O)C)C1[N+](C)(C)C)[N+](C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K14 compound treatment 0.25 6.25E-4 0.03 0.0336 1.0 1912712 TimTec1_004810 CC1=CC(C)(C)C(C(C1)C(=O)O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K15 compound treatment 0.292 0.0426 2.29 2.2906 1.0 1608847 TimTec1_004811 Cc1ccc(cc1)S(=O)(=O)N2N=NC3C4CC(C5CC=CC54)C32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K16 compound treatment 0.254 0.00462 0.25 0.2485 1.0 3211621 TimTec1_004812 FC(F)(F)c1cccc(NC(=O)NC2(CC2)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K17 compound treatment 0.267 0.0176 0.95 0.9471 1.0 3086332 TimTec1_004813 COc1nsc(Br)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K18 compound treatment 0.262 0.0126 0.68 0.6784 1.0 1299455 TimTec1_004814 CC1Nc2ccccc2C(=O)N1NC(=O)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K19 compound treatment 0.456 0.207 11.1 11.1036 1.0 1278796 TimTec1_004815 O=C(Cc1ccccc1)N2CCC(=N2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K20 compound treatment 0.349 0.0996 5.35 5.3536 1.0 1293299 TimTec1_004816 COc1ccc(CCn2c(N)cc(=O)[nH]c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K21 compound treatment 0.292 0.0426 2.29 2.2906 1.0 1371336 TimTec1_004817 CCCCC(=O)Nc1c(nc2ccccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K22 compound treatment 0.266 0.0166 0.89 0.8934 1.0 3211728 TimTec1_004818 Brc1cnn(c2ccccc2)c(=O)c1NCCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K23 mock treatment 0.258 0.00862 0.46 0.4635 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 K24 mock treatment 0.255 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L01 compound treatment 0.385 0.136 7.29 7.2882 1.0 1208379 TimTec1_004819 O=C(c1ccco1)n2c(=S)nc3ccccn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L02 compound treatment 0.268 0.0186 1.0 1.0009 1.0 3211729 TimTec1_004820 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)NCc3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L03 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3211730 TimTec1_004821 CCOC(=O)c1nc(N)c(=O)n(n1)c2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L04 compound treatment 0.246 -0.00338 -0.18 -0.1814 -1.0 3086338 TimTec1_004822 CN1C2=C(C(NC1=O)c3ccc(O)cc3)C(=O)N(CCO)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L05 compound treatment 0.255 0.00562 0.3 0.3023 1.0 3211731 TimTec1_004823 CC1(C)Cc2ccccc2C(=N1)c3sc4nc5CCCCCc5cc4c3N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L06 compound treatment 0.344 0.0946 5.08 5.0849 1.0 1225977 TimTec1_004824 Cc1cc(NC(=O)Cc2ccccc2)ccc1c3cc4ccccc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L07 compound treatment 0.484 0.235 12.61 12.6083 1.0 3086341 TimTec1_004825 CC(C)n1c(COc2ccc(Cl)cc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L08 compound treatment 0.37 0.121 6.48 6.4821 1.0 1395920 TimTec1_004826 COC(=O)C1=C(CN(C1)c2ccccc2)NN(C)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L09 compound treatment 0.435 0.186 9.98 9.9751 1.0 3086343 TimTec1_004827 Cc1ccsc1CNn2cnnc2SCc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L10 compound treatment 0.265 0.0156 0.84 0.8397 1.0 3086416 TimTec1_004828 CN(NC(=S)Nc1ccccc1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L11 compound treatment 0.353 0.104 5.57 5.5686 1.0 3211732 TimTec1_004829 Cc1nn(C(=O)c2c[nH]c3ccccc23)c(N)c1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L12 compound treatment 0.317 0.0676 3.63 3.634 1.0 3086420 TimTec1_004830 O/N=C/c1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L13 compound treatment 0.258 0.00862 0.46 0.4635 1.0 3211733 TimTec1_004831 Nn1c(S)nnc1Cc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L14 compound treatment 0.305 0.0556 2.99 2.9892 1.0 3086422 TimTec1_004832 OC/C=C/c1ccc(O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L15 compound treatment 0.392 0.143 7.66 7.6644 1.0 3211734 TimTec1_004833 COc1ccc(c2cc(n[nH]2)C(=O)N)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L16 compound treatment 0.252 0.00262 0.14 0.1411 1.0 3086423 TimTec1_004834 CC(C)(C)c1ccc(cc1)S(=O)(=O)NC(=O)c2cccc(Oc3cccc(c3)C(F)(F)F)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L17 compound treatment 0.245 -0.00438 -0.24 -0.2351 -1.0 3211735 TimTec1_004835 OCC1OC(Nc2ccccn2)C(O)C(O)C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L18 compound treatment 0.495 0.246 13.2 13.1994 1.0 1186126 TimTec1_004836 COc1ccc2c3CCc4c([nH]c5ccccc45)-c3ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L19 compound treatment 0.319 0.0696 3.74 3.7415 1.0 3086426 TimTec1_004837 Cc1cccc(C)c1OCCN2C(=O)c3ccccc3C2(O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L20 compound treatment 0.281 0.0316 1.7 1.6995 1.0 1122321 TimTec1_004838 CCC1Nc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L21 compound treatment 0.488 0.239 12.82 12.8232 1.0 1235395 TimTec1_004839 S=C(Nc1cccnc1)N(CCc2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L22 compound treatment 0.281 0.0316 1.7 1.6995 1.0 3086429 TimTec1_004840 O/N=C/C(=O)Nc1ccccc1I 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L23 mock treatment 0.252 0.00262 0.14 0.1411 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 L24 mock treatment 0.238 -0.0114 -0.61 -0.6113 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M01 compound treatment 0.32 0.0706 3.8 3.7952 1.0 1539018 TimTec1_004841 CC(C)(C)NCC(O)COc1c(Br)ccc2c1sc3nc4CCCCCn4c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M02 compound treatment 0.271 0.0216 1.16 1.1621 1.0 1251587 TimTec1_004842 CCCc1nc2c(sc3nc(COC)cc(C)c32)c4nc5ccccc5n14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M03 compound treatment 0.318 0.0686 3.69 3.6878 1.0 1774729 TimTec1_004843 O=C(OC1CS(=O)(=O)CC1OC(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M04 compound treatment 0.251 0.00162 0.09 0.0873 1.0 3086431 TimTec1_004844 CCC(=O)Nc1nc2nc(COC)cc(O)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M05 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 3211736 TimTec1_004845 CC1CC(=O)N(C(=O)C)c2ccccc2N1C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M06 compound treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1645856 TimTec1_004846 CCOC(=O)CNc1nc(Cl)nc(NCC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M07 compound treatment 0.257 0.00762 0.41 0.4098 1.0 1505508 TimTec1_004847 OC(=O)CCNS(=O)(=O)c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M08 compound treatment 0.503 0.254 13.63 13.6293 1.0 3211737 TimTec1_004848 OC(=O)Cn1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M09 compound treatment 0.258 0.00862 0.46 0.4635 1.0 3211738 TimTec1_004849 OC(C(O)c1nnc(S)n1c2ccccc2)c3nnc(S)n3c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M10 compound treatment 0.285 0.0356 1.91 1.9144 1.0 3086435 TimTec1_004850 OC(=O)c1ccc(CSc2nnc(Cc3ccccc3)n2c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M11 compound treatment 0.253 0.00362 0.19 0.1948 1.0 3211739 TimTec1_004851 CCOC(=O)CN1NC(CC)(NC1=S)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M12 compound treatment 0.289 0.0396 2.13 2.1294 1.0 3211740 TimTec1_004852 Cc1onc(c1C(=O)NCCOC2(CC3CC4CC(C3)C2)C4)c5ccccc5Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M13 compound treatment 0.459 0.21 11.26 11.2648 1.0 1320456 TimTec1_004853 Oc1ncnc2nn(nc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M14 compound treatment 0.271 0.0216 1.16 1.1621 1.0 1262859 TimTec1_004854 C=CCN1C(=O)C(Cc2c[nH]c3ccccc23)NC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M15 compound treatment 0.285 0.0356 1.91 1.9144 1.0 1260852 TimTec1_004855 COc1ccccc1N2CCSC2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M16 compound treatment 0.274 0.0246 1.32 1.3233 1.0 1602518 TimTec1_004856 COC(=O)c1cc(=O)c2c(SC)nc(nc2[nH]1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M17 compound treatment 0.483 0.234 12.55 12.5545 1.0 1218046 TimTec1_004857 CC(C)(O)C#Cc1ccc(o1)C(=O)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M18 compound treatment 0.275 0.0256 1.38 1.377 1.0 1375886 TimTec1_004858 CC(C)c1ccc(cc1)S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M19 compound treatment 0.297 0.0476 2.56 2.5593 1.0 1685209 TimTec1_004859 O=C1NC(=O)C(CCc2ccccn2)(CCc3ccccn3)C(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M20 compound treatment 0.31 0.0606 3.26 3.2579 1.0 3211741 TimTec1_004860 Cc1nnc(c2ccccc2)c(=O)n1/N=C/c3ccc(O)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M21 compound treatment 0.482 0.233 12.5 12.5008 1.0 1591983 TimTec1_004861 O=C(NC1CCCCC1)n2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M22 compound treatment 0.257 0.00762 0.41 0.4098 1.0 3086509 TimTec1_004862 Cc1cc(C)n(n1)c2n[nH]c(=S)n2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M23 mock treatment 0.261 0.0116 0.62 0.6247 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 M24 mock treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N01 compound treatment 0.239 -0.0104 -0.56 -0.5575 -1.0 1431780 TimTec1_004863 Oc1nnc(c2ncc[nH]2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N02 compound treatment 0.262 0.0126 0.68 0.6784 1.0 3211742 TimTec1_004864 CCOc1ccc(cc1S(=O)(=O)NC2CC2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N03 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 3086512 TimTec1_004865 CCN1CN(Cc2ccccc2)CNC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N04 compound treatment 0.257 0.00762 0.41 0.4098 1.0 3211743 TimTec1_004866 CC1(C2c3ccccc3OC(=O)C21C(=O)N4CCOCC4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N05 compound treatment 0.272 0.0226 1.22 1.2158 1.0 3211744 TimTec1_004867 CCCCn1c(cc(=O)c2c(C)n(c3ccccc3)c(=S)nc12)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N06 compound treatment 0.431 0.182 9.76 9.7601 1.0 3086514 TimTec1_004868 Cc1cccc(NCc2c(C#N)c3ccccc3n2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N07 compound treatment 0.551 0.302 16.21 16.2087 1.0 3211745 TimTec1_004869 CCOc1nc(OCC)nc(n1)n2cc(nn2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N08 compound treatment 0.251 0.00162 0.09 0.0873 1.0 1416515 TimTec1_004870 CCOC(=O)C1=C(NN(C)c2ccccc2)C(=O)N(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N09 compound treatment 0.514 0.265 14.22 14.2204 1.0 3211746 TimTec1_004871 Nc1nc-2c(CCc3c2cnn3c4ccccc4)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N10 compound treatment 0.257 0.00762 0.41 0.4098 1.0 1675882 TimTec1_004872 CCOC(=O)C1=C(N)C(=O)N(CCCN2CCOCC2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N11 compound treatment 0.496 0.247 13.25 13.2531 1.0 3211837 TimTec1_004873 CCOc1nc(NC(=O)NC(=O)c2c(F)cccc2F)nc(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N12 compound treatment 0.304 0.0546 2.94 2.9354 1.0 3086517 TimTec1_004874 Cn1c(/C=N/O)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N13 compound treatment 0.473 0.224 12.02 12.0171 1.0 3211838 TimTec1_004875 COC(=O)Nc1ccc2n(cnc2c1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N14 compound treatment 0.265 0.0156 0.84 0.8397 1.0 1164968 TimTec1_004876 O=C(NCCc1ccccc1)C2c3ccccc3-c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N15 compound treatment 0.255 0.00562 0.3 0.3023 1.0 3211839 TimTec1_004877 Cc1n[nH]c2nc3n(C)c(=O)n(C)c(=O)c3c(OC(=O)c4ccccc4)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N16 compound treatment 0.263 0.0136 0.73 0.7322 1.0 3086520 TimTec1_004878 CNC(=O)c1cccc(Oc2cccc(Cl)n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N17 compound treatment 0.256 0.00662 0.36 0.356 1.0 1658721 TimTec1_004879 S=C(NCCN1CCOCC1)NC2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N18 compound treatment 0.263 0.0136 0.73 0.7322 1.0 1394340 TimTec1_004880 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)c3ccccc3-c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N19 compound treatment 0.264 0.0146 0.79 0.7859 1.0 3211840 TimTec1_004881 NC(=O)C(Cc1ccccc1)NC(=O)c2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N20 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 1014469 TimTec1_004882 CC(=O)Nc1ccccc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N21 compound treatment 0.262 0.0126 0.68 0.6784 1.0 3211841 TimTec1_004883 CC(C)N(Cc1ccccc1)C(=S)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N22 compound treatment 0.278 0.0286 1.54 1.5382 1.0 3085427 TimTec1_004884 COc1ccccc1/C(=C\C)/C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N23 mock treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 N24 mock treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O01 compound treatment 0.394 0.145 7.77 7.7718 1.0 1506163 TimTec1_004885 CCOC(=O)c1c(NC(=O)c2ccccc2)sc3c4OCN(CC=C)Cc4ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O02 compound treatment 0.248 -0.00138 -0.07 -0.0739 -1.0 1693531 TimTec1_004886 CC1(C)CC(CC(C)(C)N1)NC(=S)NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O03 compound treatment 0.272 0.0226 1.22 1.2158 1.0 3085432 TimTec1_004887 Clc1ccc(NN2C(=O)c3cccc4cc(Br)cc(C2=O)c34)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O04 compound treatment 0.267 0.0176 0.95 0.9471 1.0 1234657 TimTec1_004888 O=C(CSCc1ccc2nsnc2c1)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O05 compound treatment 0.247 -0.00238 -0.13 -0.1276 -1.0 3211842 TimTec1_004889 CCCN1C(=O)CCN(C(=O)C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O06 compound treatment 0.238 -0.0114 -0.61 -0.6113 -1.0 1713735 TimTec1_004890 CC1(O)N(C2CC(C)(C)NC(C)(C)C2)C(=O)OC1(C)C3CC4CC3C=C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O07 compound treatment 0.369 0.12 6.43 6.4284 1.0 3211843 TimTec1_004891 Cn1cnnc1SCc2c(Cl)cccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O08 compound treatment 0.231 -0.0184 -0.99 -0.9874 -1.0 1260007 TimTec1_004892 CN1CCN(CC1)NC(=S)Nc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O09 compound treatment 0.305 0.0556 2.99 2.9892 1.0 3085435 TimTec1_004893 NN(CCC(=O)NC1CCCCC1)C2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O10 compound treatment 0.336 0.0866 4.66 4.655 1.0 3211844 TimTec1_004894 Clc1ccccc1C(=O)NCCOc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O11 compound treatment 0.511 0.262 14.06 14.0592 1.0 1622091 TimTec1_004895 Cc1ccc(CNC(=O)CSc2nnc(s2)N3C(=O)c4ccccc4C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O12 compound treatment 0.45 0.201 10.78 10.7812 1.0 1190874 TimTec1_004896 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(N4CCCCC4)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O13 compound treatment 0.338 0.0886 4.76 4.7625 1.0 1074879 TimTec1_004897 NC(=O)c1ccc(cc1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O14 compound treatment 0.407 0.158 8.47 8.4704 1.0 1529201 TimTec1_004898 O=C1CSC(c2c(nn(c2N1)c3ccccc3)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O15 compound treatment 0.256 0.00662 0.36 0.356 1.0 1372011 TimTec1_004899 OC(=O)C1(CCC(=O)NCc2ccccc2)CCC(=O)NC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O16 compound treatment 0.258 0.00862 0.46 0.4635 1.0 1451083 TimTec1_004900 Cc1cccc(NC(=O)CSc2nnc(CCC(=O)O)c(=O)n2N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O17 compound treatment 0.372 0.123 6.59 6.5896 1.0 1606306 TimTec1_004901 CC(=O)Nc1ccccc1c2nc3ccccc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O18 compound treatment 0.491 0.242 12.98 12.9844 1.0 3211845 TimTec1_004902 Brc1ccc(NC(=O)CSCC(=O)Nc2cccc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O19 compound treatment 0.271 0.0216 1.16 1.1621 1.0 1693543 TimTec1_004903 Cc1nonc1NC2(Nc3nonc3C)C(=O)c4ccccc4C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O20 compound treatment 0.315 0.0656 3.53 3.5266 1.0 1465796 TimTec1_004904 O=C(Sc1nc(c([nH]1)c2ccccc2)c3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O21 compound treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1609425 TimTec1_004905 CC(=O)Nc1ncc(CN2CCOCC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O22 compound treatment 0.554 0.305 16.37 16.3699 1.0 1141664 TimTec1_004906 COc1ccc(cc1)S(=O)(=O)c2cc(NS(=O)(=O)c3ccccc3)cc(C(C)C)c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O23 mock treatment 0.263 0.0136 0.73 0.7322 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 O24 mock treatment 0.251 0.00162 0.09 0.0873 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P01 compound treatment 0.345 0.0956 5.14 5.1387 1.0 3085443 TimTec1_004907 Nn1cnn2c(SCc3cccc(c3)C(F)(F)F)nnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P02 compound treatment 0.341 0.0916 4.92 4.9237 1.0 3085445 TimTec1_004908 OC1(CC(=O)c2cccc(c2)n3cnnn3)C(=O)Nc4ccccc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P03 compound treatment 0.348 0.0986 5.3 5.2999 1.0 3211846 TimTec1_004909 NCCN1C(c2c(n[nH]c2C1=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P04 compound treatment 0.318 0.0686 3.69 3.6878 1.0 3211847 TimTec1_004910 Fc1ccc(NC=C2C(=O)NC(=O)NC2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P05 compound treatment 0.26 0.0106 0.57 0.571 1.0 3085513 TimTec1_004911 Cc1ccc(c(O)c1)C(O)(c2nc3ccccc3[nH]2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P06 compound treatment 0.286 0.0366 1.97 1.9682 1.0 1787981 TimTec1_004912 CCn1c2ccccc2c3cc(NC(=O)c4ccc(OC)c(OC)c4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P07 compound treatment 0.273 0.0236 1.27 1.2696 1.0 3085795 TimTec1_004913 O=C(CC(C(=O)c1ccccc1)n2cccn2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P08 compound treatment 0.418 0.169 9.06 9.0616 1.0 3211848 TimTec1_004914 CN(/N=C\1/CCN(C2CCCCC2)C1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P09 compound treatment 0.223 -0.0264 -1.42 -1.4173 -1.0 3085796 TimTec1_004915 O=S(=O)(CCC#N)c1nnnn1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P10 compound treatment 0.471 0.222 11.91 11.9097 1.0 1492454 TimTec1_004916 COC(=O)C1=C(N)C(=O)N(C1)c2ccc(cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P11 compound treatment 0.272 0.0226 1.22 1.2158 1.0 3211849 TimTec1_004917 COc1ccc(cc1)C(=O)NC(Cc2ccccc2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P12 compound treatment 0.287 0.0376 2.02 2.0219 1.0 1062606 TimTec1_004918 N1=C(C1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P13 compound treatment 0.255 0.00562 0.3 0.3023 1.0 3085797 TimTec1_004919 COc1cc(NS(=O)(=O)N2CCCC2)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P14 compound treatment 0.266 0.0166 0.89 0.8934 1.0 3211850 TimTec1_004920 O=C(NCCCc1ccccc1)C2c3ccccc3-c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P15 compound treatment 0.238 -0.0114 -0.61 -0.6113 -1.0 3085798 TimTec1_004921 CNC(=O)C1=C(C)Nc2nc3ccccc3n2C1c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P16 compound treatment 0.238 -0.0114 -0.61 -0.6113 -1.0 1558273 TimTec1_004922 OC1C2CN3CC1(CN(C2)CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P17 compound treatment 0.539 0.29 15.56 15.5638 1.0 3211851 TimTec1_004923 O=C(Cc1ccccc1)Nc2nonc2NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P18 compound treatment 0.271 0.0216 1.16 1.1621 1.0 1454261 TimTec1_004924 CCCNC(=O)c1ccc(OC)c(OC(=O)c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P19 compound treatment 0.259 0.00962 0.52 0.5172 1.0 3211852 TimTec1_004925 CN(C)c1nc(N)nc(n1)C2CCCN2S(=O)(=O)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P20 compound treatment 0.235 -0.0144 -0.77 -0.7725 -1.0 3085799 TimTec1_004926 CS(=O)(=O)c1cccc(Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P21 compound treatment 0.233 -0.0164 -0.88 -0.88 -1.0 3085800 TimTec1_004927 CC1(C)C(OC(=O)C(C)(C)C1=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P22 compound treatment 0.281 0.0316 1.7 1.6995 1.0 1523811 TimTec1_004928 O=C(N1CCC2(Cc3ccccc3C2=O)CC1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P23 mock treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2076 P24 mock treatment 0.249 -3.75E-4 -0.02 -0.0202 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A01 compound treatment 0.267 0.0165 0.89 0.8867 1.0 1644449 TimTec1_004929 COc1cc2CN(C)C(Cc3ccc(OC(=O)C)cc3)c2cc1OBr 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A02 compound treatment 0.236 -0.0145 -0.78 -0.7792 -1.0 3085801 TimTec1_004930 CCn1c(nc2ccccc12)c3nc4ccccc4n3CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A03 compound treatment 0.236 -0.0145 -0.78 -0.7792 -1.0 3211933 TimTec1_004931 CCOC(=O)/C=C(\C)/NC1CC(C)(C)NC(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A04 compound treatment 0.233 -0.0175 -0.94 -0.9404 -1.0 3085802 TimTec1_004932 CO[C@H]1O[C@H](CO)C(=O)C(=C1N)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A05 compound treatment 0.243 -0.0075 -0.4 -0.403 -1.0 3211934 TimTec1_004933 O=c1sc2ccccc2n1COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A06 compound treatment 0.257 0.0065 0.35 0.3493 1.0 1219039 TimTec1_004934 CN1CCN(Cc2c3ccccc3cc4ccccc24)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A07 compound treatment 0.221 -0.0295 -1.59 -1.5853 -1.0 3085803 TimTec1_004935 Cc1noc(C)c1C(=O)Nc2nnc(SCC(=O)O)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A08 compound treatment 0.237 -0.0135 -0.73 -0.7255 -1.0 1640299 TimTec1_004936 CN(Cc1ccc2OCOc2c1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A09 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1531940 TimTec1_004937 OC(C(=O)c1ccccc1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A10 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 3211935 TimTec1_004938 Cn1nnnc1c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A11 compound treatment 0.268 0.0175 0.94 0.9404 1.0 1334202 TimTec1_004939 CC(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4)c(C)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A12 compound treatment 0.283 0.0325 1.75 1.7465 1.0 1403452 TimTec1_004940 COc1ccccc1c2nn(CN(c3ccccc3)c4ccccc4)c(=S)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A13 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 1575737 TimTec1_004941 O=C(c1ccc2OCCCOc2c1)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A14 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1152651 TimTec1_004942 O[C@@H](C1CC2CCN1CC2C=C)c3cnc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A15 compound treatment 0.261 0.0105 0.56 0.5642 1.0 1401869 TimTec1_004943 CC1(C)CC2(CCCN(CC#N)C2)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A16 compound treatment 0.258 0.0075 0.4 0.403 1.0 1670175 TimTec1_004944 Cc1nc2c(sc3nc4CCCCc4c(c5ccco5)c32)c(=O)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A17 compound treatment 0.275 0.0245 1.32 1.3166 1.0 1247373 TimTec1_004945 Brc1ccnc(N2C(=O)c3ccccc3C2=O)c1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A18 compound treatment 0.336 0.0855 4.59 4.5946 1.0 3211937 TimTec1_004946 Nc1c(sc2nc(ccc12)c3cccs3)C(=O)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A19 compound treatment 0.261 0.0105 0.56 0.5642 1.0 3085804 TimTec1_004947 CC(=C)C(=O)N1C(COC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A20 compound treatment 0.258 0.0075 0.4 0.403 1.0 1254800 TimTec1_004948 CNc1nc(OC)cc(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A21 compound treatment 0.289 0.0385 2.07 2.0689 1.0 3211938 TimTec1_004949 O=C(NCc1ccco1)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A22 compound treatment 0.269 0.0185 0.99 0.9942 1.0 1033657 TimTec1_004950 CS(=O)(=O)c1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A23 mock treatment 0.253 0.0025 0.13 0.1343 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 A24 mock treatment 0.263 0.0125 0.67 0.6717 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B01 compound treatment 0.257 0.0065 0.35 0.3493 1.0 3211939 TimTec1_004951 CC(C)(C)C(=O)Nc1nccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B02 compound treatment 0.474 0.224 12.01 12.0104 1.0 3211940 TimTec1_004952 O=S(=O)(/N=C(\Nc1cccc2ccccc12)/c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B03 compound treatment 0.254 0.0035 0.19 0.1881 1.0 1143395 TimTec1_004953 CN(C)c1nc2n(C)c(=O)[nH]c(=O)c2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B04 compound treatment 0.601 0.35 18.84 18.8351 1.0 3085810 TimTec1_004954 CCOC(=O)c1cn(nc1C(F)(F)F)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B05 compound treatment 0.336 0.0855 4.59 4.5946 1.0 3211941 TimTec1_004955 CCc1[o+]c(cc2CCCCc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B06 compound treatment 0.286 0.0355 1.91 1.9077 1.0 1673469 TimTec1_004956 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B07 compound treatment 0.399 0.148 7.98 7.9801 1.0 3211942 TimTec1_004957 O=C/1CCCC\C1=C\Nc2cccc(N/C=C\3/CCCCC3=O)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B08 compound treatment 0.445 0.195 10.45 10.452 1.0 1541165 TimTec1_004958 Cc1nonc1NC(=O)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B09 compound treatment 0.293 0.0425 2.28 2.2839 1.0 1429667 TimTec1_004959 COc1cccc(C(N2CCCC2)c3cc4OCOc4cc3O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B10 compound treatment 0.252 0.0015 0.08 0.0806 1.0 3085814 TimTec1_004960 CC(=O)Nc1sc(C)c(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B11 compound treatment 0.262 0.0115 0.62 0.618 1.0 1366449 TimTec1_004961 CN(C)c1ccc(cc1)C2CC(C)(Oc3cc4OCOc4cc23)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B12 compound treatment 0.239 -0.0115 -0.62 -0.618 -1.0 3085816 TimTec1_004962 CC1=NNC(=O)C1C(C(C#N)C#N)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B13 compound treatment 0.252 0.0015 0.08 0.0806 1.0 1019517 TimTec1_004963 COc1cc(cc(OC)c1O)C2C3C(COC3=O)Cc4c(O)c5OCOc5cc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B14 compound treatment 0.271 0.0205 1.1 1.1016 1.0 1563233 TimTec1_004964 CCSc1nc2n(C)c(=O)[nH]c(=O)c2n1Cc3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B15 compound treatment 0.271 0.0205 1.1 1.1016 1.0 3085858 TimTec1_004965 COc1cnc(SC)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B16 compound treatment 0.515 0.265 14.21 14.2137 1.0 1621047 TimTec1_004966 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc(Cl)cc3Cl)c(Br)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B17 compound treatment 0.305 0.0545 2.93 2.9287 1.0 1547656 TimTec1_004967 CCOc1nc2ccccc2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B18 compound treatment 0.285 0.0345 1.85 1.854 1.0 1446595 TimTec1_004968 CC(C)c1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4n3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B19 compound treatment 0.264 0.0135 0.73 0.7255 1.0 2747 TimTec1_004969 Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B20 compound treatment 0.534 0.283 15.23 15.2347 1.0 1295276 TimTec1_004970 NC(=S)c1[nH]nc2c1[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B21 compound treatment 0.309 0.0585 3.14 3.1437 1.0 1170984 TimTec1_004971 Cc1ccc(SC(CC(=O)c2ccc(cc2)C(C)(C)C)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B22 compound treatment 0.522 0.272 14.59 14.5898 1.0 3085864 TimTec1_004972 CCCCC1SC(=NNC1=O)/N=C/c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B23 mock treatment 0.236 -0.0145 -0.78 -0.7792 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 B24 mock treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C01 compound treatment 0.275 0.0245 1.32 1.3166 1.0 1262842 TimTec1_004973 CCOC(=O)C1(CCN(c2ccccc2C1=O)S(=O)(=O)c3ccc(C)cc3)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C02 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 1630883 TimTec1_004974 Cn1c(nc2ccccc12)P(=O)(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C03 compound treatment 0.256 0.0055 0.3 0.2956 1.0 3211943 TimTec1_004975 CCc1cccc(NC(=O)OC2CCN(C)CC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C04 compound treatment 0.345 0.0945 5.08 5.0782 1.0 3085867 TimTec1_004976 Oc1ccccc1/N=C/c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C05 compound treatment 0.279 0.0285 1.53 1.5315 1.0 1684419 TimTec1_004977 CC(=O)Nc1ccc2n(CC=C)c(=O)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C06 compound treatment 0.236 -0.0145 -0.78 -0.7792 -1.0 3085869 TimTec1_004978 CN1CCN(Cc2c(Cl)cccc2Cl)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C07 compound treatment 0.273 0.0225 1.21 1.2091 1.0 1544605 TimTec1_004979 Cc1ccc(F)c2[nH]cc3c(=O)n(nc3c12)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C08 compound treatment 0.242 -0.0085 -0.46 -0.4568 -1.0 1692460 TimTec1_004980 CSc1ccc(CN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C09 compound treatment 0.285 0.0345 1.85 1.854 1.0 1697399 TimTec1_004981 CC(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)C(=O)ON4C(=O)CCC4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C10 compound treatment 0.351 0.101 5.4 5.4007 1.0 1553247 TimTec1_004982 Nc1nc(c(Cl)s1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C11 compound treatment 0.492 0.241 12.98 12.9777 1.0 1170357 TimTec1_004983 CC(C)(C)OC(=O)N1CCCC1C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C12 compound treatment 0.354 0.103 5.56 5.5619 1.0 1143084 TimTec1_004984 O=C(CSCc1c[nH]c2ccccc12)Nc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C13 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1113621 TimTec1_004985 S=C(N1CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C14 compound treatment 0.322 0.0715 3.84 3.8423 1.0 3211944 TimTec1_004986 OC[C@H]1[C@@H](C[C@@H]2OC(=O)C[C@H]12)OC(=O)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C15 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1673684 TimTec1_004987 COc1nc(nc(n1)N2CCc3ccccc23)N4CCc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C16 compound treatment 0.299 0.0485 2.61 2.6063 1.0 3085875 TimTec1_004988 CCc1nc(SC)c(C#N)c2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C17 compound treatment 0.273 0.0225 1.21 1.2091 1.0 1436730 TimTec1_004989 CC1(C)CC(=O)C(C(=C1)O)C2(O)C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C18 compound treatment 0.276 0.0255 1.37 1.3703 1.0 1271503 TimTec1_004990 COc1ccc(OC)c(c1)C2C(=C(N)Oc3cc(C)oc(=O)c23)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C19 compound treatment 0.258 0.0075 0.4 0.403 1.0 3085916 TimTec1_004991 CC[n+]1ccc(/C=C/c2ccc(OC)c(OC)c2OC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C20 compound treatment 0.276 0.0255 1.37 1.3703 1.0 3085918 TimTec1_004992 Nc1nc(OCC(F)(F)F)cc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C21 compound treatment 0.321 0.0705 3.79 3.7885 1.0 3211998 TimTec1_004993 CC1CCN(CC1)C(=O)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C22 compound treatment 0.472 0.222 11.9 11.9029 1.0 3085922 TimTec1_004994 Cc1nc2ccccc2c(=O)n1/N=C/c3ccc4ncccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C23 mock treatment 0.26 0.0095 0.51 0.5105 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 C24 mock treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D01 compound treatment 0.24 -0.0105 -0.56 -0.5642 -1.0 1018493 TimTec1_004995 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D02 compound treatment 0.269 0.0185 0.99 0.9942 1.0 1571869 TimTec1_004996 Cc1ccc(cc1)S(=O)(=O)NC(=O)SC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D03 compound treatment 0.264 0.0135 0.73 0.7255 1.0 1513997 TimTec1_004997 Cc1cccc(Oc2ncc(F)c(Oc3cccc(C)c3)n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D04 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1365828 TimTec1_004998 CSc1nc2NC(=CC(c3ccccc3)n2n1)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D05 compound treatment 0.306 0.0555 2.98 2.9825 1.0 3085925 TimTec1_004999 CCc1[o+]c(cc2cc(OC)c(OC)cc12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D06 compound treatment 0.302 0.0515 2.77 2.7675 1.0 1921582 TimTec1_005000 Cc1cc(C)n(n1)C(=O)c2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D07 compound treatment 0.363 0.113 6.05 6.0455 1.0 3211999 TimTec1_005001 O=C/1CCCC\C1=C\Nc2ccc(N/C=C\3/CCCCC3=O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D08 compound treatment 0.254 0.0035 0.19 0.1881 1.0 1174633 TimTec1_005002 CC(NC(=O)c1cccc(N)c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D09 compound treatment 0.238 -0.0125 -0.67 -0.6717 -1.0 1210964 TimTec1_005003 COc1ccc(cc1)C(C)c2cc3OCOc3cc2OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D10 compound treatment 0.316 0.0655 3.52 3.5198 1.0 3212000 TimTec1_005004 Clc1ccc(NC(=O)c2cccs2)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D11 compound treatment 0.322 0.0715 3.84 3.8423 1.0 1124331 TimTec1_005005 CN(C)c1ccc(cc1)C(N2CCCCC2)c3cc4OCOc4cc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D12 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1007160 TimTec1_005006 NC(=N)Nc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D13 compound treatment 0.239 -0.0115 -0.62 -0.618 -1.0 3085929 TimTec1_005007 Cn1c(=O)n(C)c2nc([nH]c2c1=O)[n+]3ccc(cc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D14 compound treatment 0.362 0.112 5.99 5.9918 1.0 1272092 TimTec1_005008 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc4ccccc4c3)c(S)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D15 compound treatment 0.245 -0.0055 -0.3 -0.2956 -1.0 1371696 TimTec1_005009 OC(=O)Cn1ccsc1=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D16 compound treatment 0.239 -0.0115 -0.62 -0.618 -1.0 3085931 TimTec1_005010 CCOC(=O)N(c1ccccc1)S(=O)(=O)c2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D17 compound treatment 0.267 0.0165 0.89 0.8867 1.0 1391232 TimTec1_005011 CCOc1nc2ccccc2c(=O)n1CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D18 compound treatment 0.397 0.146 7.87 7.8726 1.0 1600779 TimTec1_005012 NC(=O)c1c(oc2ccc(O)cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D19 compound treatment 0.463 0.212 11.42 11.4193 1.0 3085934 TimTec1_005013 Cn1cnnc1SC/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D20 compound treatment 0.332 0.0815 4.38 4.3796 1.0 3212001 TimTec1_005014 N(=c/1\[nH]c2c(ccc3ccccc23)s1)\c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D21 compound treatment 0.297 0.0465 2.5 2.4988 1.0 1597367 TimTec1_005015 OC(=O)C(CC(=O)c1ccc(Cl)cc1)SCc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D22 compound treatment 0.517 0.267 14.32 14.3212 1.0 3212002 TimTec1_005016 N1N=C(SC=C1c2ccccc2)/N=C/c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D23 mock treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 D24 mock treatment 0.235 -0.0155 -0.83 -0.8329 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E01 compound treatment 0.422 0.172 9.22 9.2161 1.0 1071315 TimTec1_005017 COc1ccc2c3CCCC(=O)c3ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E02 compound treatment 0.561 0.311 16.69 16.6856 1.0 1454628 TimTec1_005018 Oc1ccc(C(=O)COc2ccccc2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E03 compound treatment 0.307 0.0565 3.04 3.0362 1.0 3085938 TimTec1_005019 CCOC(=O)Nc1nc2c(Cl)cccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E04 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1030338 TimTec1_005020 COC(=O)c1nc[nH]c1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E05 compound treatment 0.353 0.102 5.51 5.5081 1.0 3085974 TimTec1_005021 CCOC(=O)n1c(=O)sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E06 compound treatment 0.239 -0.0115 -0.62 -0.618 -1.0 3085976 TimTec1_005022 CN1CCN(CC2CCC=CC2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E07 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1140829 TimTec1_005023 CN(C)S(=O)(=O)c1ccc(C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E08 compound treatment 0.237 -0.0135 -0.73 -0.7255 -1.0 1363499 TimTec1_005024 CCCN(CCO)CC1CCC=CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E09 compound treatment 0.297 0.0465 2.5 2.4988 1.0 1427526 TimTec1_005025 O=c1c(Oc2ccccc2)coc3cc(OCc4ccccc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E10 compound treatment 0.242 -0.0085 -0.46 -0.4568 -1.0 1637231 TimTec1_005026 COC1(CCCC2(CCC1)C(=O)O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E11 compound treatment 0.528 0.278 14.91 14.9123 1.0 1442714 TimTec1_005027 CCOC(=O)c1ccc(o1)c2coc3cc(O)cc(O)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E12 compound treatment 0.362 0.112 5.99 5.9918 1.0 1234769 TimTec1_005028 COc1ccc(cc1)c2cc(NC(=O)Nc3ccccc3)n(n2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E13 compound treatment 0.265 0.0145 0.78 0.7792 1.0 1381033 TimTec1_005029 COc1cc(Cl)cc(C(=O)O)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E14 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1056436 TimTec1_005030 CC(C)c1nc2nc(N)nc(N)c2nc1C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E15 compound treatment 0.253 0.0025 0.13 0.1343 1.0 1074483 TimTec1_005031 CCN(C(=O)Nc1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E16 compound treatment 0.268 0.0175 0.94 0.9404 1.0 3212003 TimTec1_005032 Cc1s/c(=N/c2ccccc2)/[nH]c1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E17 compound treatment 0.592 0.342 18.35 18.3515 1.0 3212004 TimTec1_005033 C(=N/c1cc(nn1c2ccccc2)c3ccccc3)\c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E18 compound treatment 0.266 0.0155 0.83 0.8329 1.0 3085984 TimTec1_005034 COc1ccc(/C=C/2\C(=NC(=NC2=O)S)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E19 compound treatment 0.489 0.238 12.82 12.8165 1.0 3212005 TimTec1_005035 CCc1ccc(NC(=O)CSc2nncn2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E20 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 3085985 TimTec1_005036 Cc1cc(nc(N)n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E21 compound treatment 0.315 0.0645 3.47 3.4661 1.0 3212006 TimTec1_005037 Cc1ccc(cc1)C(=O)N/C(=C\C=C/c2ccccc2)/C(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E22 compound treatment 0.337 0.0865 4.65 4.6483 1.0 3085988 TimTec1_005038 Oc1ccc(/C=N\C2c3ccccc3-c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E23 mock treatment 0.269 0.0185 0.99 0.9942 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 E24 mock treatment 0.256 0.0055 0.3 0.2956 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F01 compound treatment 0.265 0.0145 0.78 0.7792 1.0 3212007 TimTec1_005039 C[n+]1c(/C=C/Nc2ccccc2)sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F02 compound treatment 0.254 0.0035 0.19 0.1881 1.0 3085989 TimTec1_005040 Cn1c(=O)[nH]c(=O)c2n3CCCC(c3nc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F03 compound treatment 0.258 0.0075 0.4 0.403 1.0 3212008 TimTec1_005041 Clc1ccc(cc1)c2nc3sc4CCCCc4c3c(=O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F04 compound treatment 0.265 0.0145 0.78 0.7792 1.0 1188459 TimTec1_005042 OC(CN(Cc1ccccc1)Cc2ccccc2)Cn3c4ccccc4c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F05 compound treatment 0.341 0.0905 4.86 4.8633 1.0 3085992 TimTec1_005043 COC(=O)C(Cc1c[nH]c2ccccc12)/N=C/c3cc(Cl)cc(Cl)c3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F06 compound treatment 0.308 0.0575 3.09 3.0899 1.0 1464296 TimTec1_005044 CCCOC(=O)c1c(N)sc2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F07 compound treatment 0.277 0.0265 1.42 1.4241 1.0 3085994 TimTec1_005045 CC1(C)CC(=O)C/C(=N\CC(=O)O)/C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F08 compound treatment 0.526 0.276 14.8 14.8048 1.0 3212009 TimTec1_005046 COc1cccc(c1)c2nnc(o2)c3ccc(NC(=O)C(F)(F)F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F09 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1692415 TimTec1_005047 COc1ccccc1C(C2=C(O)COC2=O)c3cc4OCOc4cc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F10 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1261046 TimTec1_005048 O=C(Nc1nccs1)c2ccccc2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F11 compound treatment 0.307 0.0565 3.04 3.0362 1.0 1427389 TimTec1_005049 Oc1cc2OCOc2cc1C(Nc3ccccn3)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F12 compound treatment 0.358 0.108 5.78 5.7768 1.0 1182617 TimTec1_005050 CC(C)(C)C(=O)C1C2CCC1C(O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F13 compound treatment 0.299 0.0485 2.61 2.6063 1.0 1471843 TimTec1_005051 Cn1c(SCC(=O)OCC(=O)c2ccc(Br)cc2)nc3n(C)c(=O)[nH]c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F14 compound treatment 0.504 0.254 13.62 13.6226 1.0 1227820 TimTec1_005052 CC1CCN(CC1)C(=O)COc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F15 compound treatment 0.273 0.0225 1.21 1.2091 1.0 1067946 TimTec1_005053 Cc1nnc(o1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F16 compound treatment 0.268 0.0175 0.94 0.9404 1.0 3212010 TimTec1_005054 CCOC(=O)N(c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F17 compound treatment 0.24 -0.0105 -0.56 -0.5642 -1.0 1743351 TimTec1_005055 CCOC(=O)CNc1nc(N)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F18 compound treatment 0.592 0.342 18.35 18.3515 1.0 3212069 TimTec1_005056 Sc1nnc2c3cc(Br)ccc3n(CC=C)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F19 compound treatment 0.34 0.0895 4.81 4.8095 1.0 3086039 TimTec1_005057 OC(=O)c1ccc(Sc2ccccn2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F20 compound treatment 0.484 0.234 12.55 12.5478 1.0 3212070 TimTec1_005058 CC1SC(=NNC1=O)/N=C/c2ccc(cc2)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F21 compound treatment 0.265 0.0145 0.78 0.7792 1.0 1338088 TimTec1_005059 Cc1ccc(cc1)C(=O)CC(SC2CCCCC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F22 compound treatment 0.274 0.0235 1.26 1.2628 1.0 3212071 TimTec1_005060 Cc1c(/N=c/2\scc(c3ccccc3)n2c4ccccc4)c(=O)n(c5ccccc5)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F23 mock treatment 0.26 0.0095 0.51 0.5105 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 F24 mock treatment 0.231 -0.0195 -1.05 -1.0479 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G01 compound treatment 0.254 0.0035 0.19 0.1881 1.0 3086042 TimTec1_005061 CCOC(=O)C1=C(O)C(=O)N(C1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G02 compound treatment 0.242 -0.0085 -0.46 -0.4568 -1.0 3212072 TimTec1_005062 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G03 compound treatment 0.232 -0.0185 -0.99 -0.9942 -1.0 1400641 TimTec1_005063 C=CCON1C(=O)C2C3OC(C=C3)C2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G04 compound treatment 0.237 -0.0135 -0.73 -0.7255 -1.0 3212073 TimTec1_005064 C[N+](C)(C)[C@H]1C(O)O[C@@H]2C(O)CO[C@H]12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G05 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1411352 TimTec1_005065 C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)C4(OCCO4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G06 compound treatment 0.378 0.128 6.85 6.8516 1.0 3212074 TimTec1_005066 CN1CCN(Cc2ccc[nH]2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G07 compound treatment 0.407 0.157 8.41 8.41 1.0 3086046 TimTec1_005067 COc1ccc(cc1)c2nc3ccsc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G08 compound treatment 0.257 0.0065 0.35 0.3493 1.0 1405970 TimTec1_005068 CN(C)CCN(CC1CC2CC1C=C2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G09 compound treatment 0.238 -0.0125 -0.67 -0.6717 -1.0 1084368 TimTec1_005069 OC(=O)C1CSC2(CCCCC2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G10 compound treatment 0.298 0.0475 2.55 2.5526 1.0 1144864 TimTec1_005070 CCN1C(=O)c2cccc3c(NC(=O)C)ccc1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G11 compound treatment 0.238 -0.0125 -0.67 -0.6717 -1.0 3212075 TimTec1_005071 Cc1[nH]cnc1C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G12 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 1717981 TimTec1_005072 Oc1ccc(=O)n(CN(c2ccccc2)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G13 compound treatment 0.257 0.0065 0.35 0.3493 1.0 1174597 TimTec1_005073 CCc1cc2OCCOc2cc1C(=O)CCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G14 compound treatment 0.244 -0.0065 -0.35 -0.3493 -1.0 3086051 TimTec1_005074 CC1CC(C)(C)N=C(O1)C(=C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G15 compound treatment 0.258 0.0075 0.4 0.403 1.0 1409343 TimTec1_005075 O=C1N(CNN2CCCc3ccccc23)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G16 compound treatment 0.286 0.0355 1.91 1.9077 1.0 1629224 TimTec1_005076 CSc1ccc(cc1)c2[nH]c(=N)sc2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G17 compound treatment 0.24 -0.0105 -0.56 -0.5642 -1.0 1378559 TimTec1_005077 CCN(CC)c1nc(NC(C)(C)C)nc(NC(C)(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G18 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1733553 TimTec1_005078 Oc1nc2CCCc2c(=O)n1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G19 compound treatment 0.495 0.245 13.14 13.1389 1.0 3086099 TimTec1_005079 Clc1ccc(SCC(=O)Nc2cccc(Cl)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G20 compound treatment 0.489 0.238 12.82 12.8165 1.0 1367022 TimTec1_005080 Oc1ccccc1OCC(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G21 compound treatment 0.245 -0.0055 -0.3 -0.2956 -1.0 3212076 TimTec1_005081 O=C(NCC1CCCO1)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G22 compound treatment 0.555 0.304 16.36 16.3632 1.0 3086101 TimTec1_005082 O=S(=O)(c1ccc(/N=C\c2ccncc2)cc1)c3ccc(/N=C\c4ccncc4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G23 mock treatment 0.262 0.0115 0.62 0.618 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 G24 mock treatment 0.252 0.0015 0.08 0.0806 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H01 compound treatment 0.267 0.0165 0.89 0.8867 1.0 3212077 TimTec1_005083 CC[n+]1c(/C=C/Nc2ccccc2)sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H02 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 1673284 TimTec1_005084 CC(=C)c1cccc(c1)C(C)(C)NC(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H03 compound treatment 0.257 0.0065 0.35 0.3493 1.0 3086104 TimTec1_005085 Clc1nc(nc2sc3CCCCc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H04 compound treatment 0.259 0.0085 0.46 0.4568 1.0 3212078 TimTec1_005086 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)/c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H05 compound treatment 0.273 0.0225 1.21 1.2091 1.0 1072337 TimTec1_005087 CCCC(=O)Oc1ccc2c(C)cc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H06 compound treatment 0.429 0.178 9.59 9.5922 1.0 1560027 TimTec1_005088 Cc1ccccc1C(=O)Nc2cc3CCCCc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H07 compound treatment 0.252 0.0015 0.08 0.0806 1.0 3086107 TimTec1_005089 OC(=O)c1ccc(/N=C/c2cccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H08 compound treatment 0.275 0.0245 1.32 1.3166 1.0 1735547 TimTec1_005090 O=C1CCC(=O)N1c2ccc3c(c2)oc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H09 compound treatment 0.238 -0.0125 -0.67 -0.6717 -1.0 1148656 TimTec1_005091 COc1ccccc1C(C2=C(COC2=O)OC(=O)C)c3cc4OCOc4cc3OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H10 compound treatment 0.435 0.185 9.91 9.9146 1.0 3212079 TimTec1_005092 Fc1ccccc1NC(=O)CSCC(=O)Nc2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H11 compound treatment 0.284 0.0335 1.8 1.8002 1.0 1232879 TimTec1_005093 COc1ccc(cc1)C(N2CCOCC2)c3cc4OCOc4cc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H12 compound treatment 0.313 0.0625 3.36 3.3586 1.0 1704797 TimTec1_005094 O=C(CCc1ccccc1)N2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H13 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1531317 TimTec1_005095 CCCn1c(nc2n(C)c(=O)[nH]c(=O)c12)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H14 compound treatment 0.26 0.0095 0.51 0.5105 1.0 1213903 TimTec1_005096 CC(C)(C)c1ccccc1OCC(=O)Nc2ccc(OCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H15 compound treatment 0.275 0.0245 1.32 1.3166 1.0 3212080 TimTec1_005097 CSc1nc(N)c(C#N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H16 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1603630 TimTec1_005098 CCOC(=O)N(c1ccc(OC)cc1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H17 compound treatment 0.278 0.0275 1.48 1.4778 1.0 1625154 TimTec1_005099 CCn1c(=O)c(C(=O)NC)c(O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H18 compound treatment 0.302 0.0515 2.77 2.7675 1.0 3212081 TimTec1_005100 COc1ccc(c2n[nH]c(C)c2Oc3ccccc3)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H19 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 1424497 TimTec1_005101 CCOC(=O)C1=C(C)NC(=O)NC1c2c(Cl)nc3c(C)cccn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H20 compound treatment 0.509 0.259 13.89 13.8912 1.0 3212082 TimTec1_005102 COc1ccc(/C=N/C2=NNC(=O)CS2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H21 compound treatment 0.254 0.0035 0.19 0.1881 1.0 1547308 TimTec1_005103 CC(C)(C)c1ccc(cc1)C(=O)CC(SC2CCCCC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H22 compound treatment 0.515 0.265 14.21 14.2137 1.0 3212083 TimTec1_005104 COc1ccc(/C=N/C2=NNC(=CS2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H23 mock treatment 0.251 5.0E-4 0.03 0.0269 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 H24 mock treatment 0.239 -0.0115 -0.62 -0.618 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I01 compound treatment 0.228 -0.0225 -1.21 -1.2091 -1.0 1210543 TimTec1_005105 O=C(c1ccccc1)C2(OCCCCO2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I02 compound treatment 0.28 0.0295 1.59 1.5853 1.0 3212084 TimTec1_005106 CN1C(=O)/C(=C\NC(=O)C)/C(=C(C#N)C1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I03 compound treatment 0.305 0.0545 2.93 2.9287 1.0 1253003 TimTec1_005107 COC(C)OC(=O)Cn1c(=O)sc2cccc(Cl)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I04 compound treatment 0.242 -0.0085 -0.46 -0.4568 -1.0 1054992 TimTec1_005108 Brc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I05 compound treatment 0.407 0.157 8.41 8.41 1.0 3212085 TimTec1_005109 Cc1ccccc1Nc2cc(C)c(C#N)c3nc4ccccc4n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I06 compound treatment 0.26 0.0095 0.51 0.5105 1.0 1286333 TimTec1_005110 CCn1c2ccccc2c3cc(CN(C)Cc4ccccc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I07 compound treatment 0.266 0.0155 0.83 0.8329 1.0 1318051 TimTec1_005111 COc1ccc2OCc3ccccc3C(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I08 compound treatment 0.236 -0.0145 -0.78 -0.7792 -1.0 1348090 TimTec1_005112 CN(C)CCN(Cc1ccsc1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I09 compound treatment 0.286 0.0355 1.91 1.9077 1.0 1334512 TimTec1_005113 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C34CC5CC4CCC(C5)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I10 compound treatment 0.429 0.178 9.59 9.5922 1.0 1920628 TimTec1_005114 CN1/C(=C/C(=O)c2ccco2)/Sc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I11 compound treatment 0.232 -0.0185 -0.99 -0.9942 -1.0 3086180 TimTec1_005115 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I12 compound treatment 0.509 0.259 13.89 13.8912 1.0 3212145 TimTec1_005116 CCOc1ccc(cc1)c2n[nH]c(=S)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I13 compound treatment 0.255 0.0045 0.24 0.2418 1.0 3086182 TimTec1_005117 O=C(Nn1cnnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I14 compound treatment 0.258 0.0075 0.4 0.403 1.0 3212146 TimTec1_005118 CCOc1ccc(/C=C/C(=O)Sc2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I15 compound treatment 0.266 0.0155 0.83 0.8329 1.0 1487889 TimTec1_005119 OC(CNCN1C(=O)c2ccccc2C1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I16 compound treatment 0.296 0.0455 2.45 2.4451 1.0 3212147 TimTec1_005120 Cc1cc(C)c(C#N)c(SCC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I17 compound treatment 0.257 0.0065 0.35 0.3493 1.0 1921119 TimTec1_005121 CCNc1nc(OC(C(F)(F)F)C(F)(F)F)nc(n1)N(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I18 compound treatment 0.263 0.0125 0.67 0.6717 1.0 3086186 TimTec1_005122 CS/C(=N\C#N)/NC1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I19 compound treatment 0.261 0.0105 0.56 0.5642 1.0 3212148 TimTec1_005123 O=C/1N(C2CCS(=O)(=O)C2)C(=S)S\C1=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I20 compound treatment 0.376 0.126 6.74 6.7441 1.0 1623935 TimTec1_005124 CCN(CC)c1ccc(N=C2C(=C(C#N)C#N)c3ccccc3C2=C(C#N)C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I21 compound treatment 0.349 0.0985 5.29 5.2932 1.0 3086189 TimTec1_005125 COCCN1C(=O)/C(=C\c2ccc3OCOc3c2)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I22 compound treatment 0.256 0.0055 0.3 0.2956 1.0 3212149 TimTec1_005126 COc1cc2CC[C@H](NC(=O)C(F)(F)F)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I23 mock treatment 0.258 0.0075 0.4 0.403 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 I24 mock treatment 0.263 0.0125 0.67 0.6717 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J01 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 3086191 TimTec1_005127 CC(C)C1CCC(C)CC1OC(=O)CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J02 compound treatment 0.284 0.0335 1.8 1.8002 1.0 1218294 TimTec1_005128 CC(C)(C)C(=O)NC(=S)Nc1cccc(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J03 compound treatment 0.39 0.14 7.5 7.4964 1.0 1240106 TimTec1_005129 C(Nc1ncnc2sc3CCCCc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J04 compound treatment 0.317 0.0665 3.57 3.5736 1.0 1554580 TimTec1_005130 Ic1ccccc1NC(=O)C2CN(C(=O)C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J05 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 3212150 TimTec1_005131 OC(=O)C(Cc1c[nH]cn1)/N=C/c2cccc(CC=C)c2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J06 compound treatment 0.275 0.0245 1.32 1.3166 1.0 1532567 TimTec1_005132 CCCOc1ccccc1C2NC(=S)NC(=C2C(=O)OC3CCCC(C)C3)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J07 compound treatment 0.236 -0.0145 -0.78 -0.7792 -1.0 3086259 TimTec1_005133 O=S(=O)(C1CCS(=O)(=O)C1)C2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J08 compound treatment 0.253 0.0025 0.13 0.1343 1.0 1186821 TimTec1_005134 Cc1cc(C)c(NC(=O)C2CC3C4C=CC=CC4C2c5ccccc35)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J09 compound treatment 0.255 0.0045 0.24 0.2418 1.0 3212151 TimTec1_005135 COc1ccccc1C2C(C)C(C)(O)Oc3cc4OCOc4cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J10 compound treatment 0.402 0.152 8.14 8.1413 1.0 1139775 TimTec1_005136 Cc1cc(C(=O)O)c(CSc2ncn[nH]2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J11 compound treatment 0.281 0.0305 1.64 1.639 1.0 1141408 TimTec1_005137 Cc1ccccc1Cn2cnc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J12 compound treatment 0.232 -0.0185 -0.99 -0.9942 -1.0 1449011 TimTec1_005138 Cc1ccc(N2C(=O)CC(=O)N(C2=O)c3ccc(C)cc3C)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J13 compound treatment 0.438 0.188 10.08 10.0759 1.0 1586155 TimTec1_005139 CC1=C(C(C(=C(C)N1)C(=O)Nc2ccccc2)c3ccccn3)C(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J14 compound treatment 0.314 0.0635 3.41 3.4124 1.0 3086263 TimTec1_005140 CC(C)c1ccc(OCC(=O)Nc2ccccc2C(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J15 compound treatment 0.319 0.0685 3.68 3.681 1.0 1332067 TimTec1_005141 CCOC(=O)c1c(C)oc(NC(=O)Nc2ccc(F)cc2)c1C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J16 compound treatment 0.4 0.149 8.03 8.0338 1.0 1544744 TimTec1_005142 Cc1c(OCc2ccc(F)cc2)ccc3c4CCCCc4c(=O)oc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J17 compound treatment 0.439 0.189 10.13 10.1296 1.0 1496408 TimTec1_005143 CCc1nnc(NC(=O)CC(=O)Nc2ccccc2C(=O)O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J18 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 1851913 TimTec1_005144 CC(C)CC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J19 compound treatment 0.252 0.0015 0.08 0.0806 1.0 1716165 TimTec1_005145 NC(=O)c1sc(=S)n(c1N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J20 compound treatment 0.456 0.205 11.04 11.0431 1.0 3086267 TimTec1_005146 CC1SC(=NNC1=O)/N=C/c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J21 compound treatment 0.266 0.0155 0.83 0.8329 1.0 3212152 TimTec1_005147 OC(=O)C(CC(=O)c1ccc(Cl)cc1)N(Cc2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J22 compound treatment 0.304 0.0535 2.87 2.875 1.0 3086269 TimTec1_005148 C=CCN1C(SC=C1c2ccccc2)/N=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J23 mock treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 J24 mock treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K01 compound treatment 0.442 0.192 10.29 10.2908 1.0 1023027 TimTec1_005149 Oc1ccccc1C(=O)CC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K02 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 3212153 TimTec1_005150 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K03 compound treatment 0.256 0.0055 0.3 0.2956 1.0 3086271 TimTec1_005151 CC(C)NC(=O)C[n+]1csc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K04 compound treatment 0.259 0.0085 0.46 0.4568 1.0 1118603 TimTec1_005152 CN1CCN(Cc2cc(Br)cs2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K05 compound treatment 0.49 0.239 12.87 12.8702 1.0 3212154 TimTec1_005153 CC(O)c1cc(NC(=O)c2ccccc2)c(=O)oc1/C=C/N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K06 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 3086274 TimTec1_005154 CN(Cc1ccccc1)Cc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K07 compound treatment 0.476 0.226 12.12 12.1179 1.0 3212155 TimTec1_005155 O=C(/C=C/c1cccc(Oc2ccccc2)c1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K08 compound treatment 0.258 0.0075 0.4 0.403 1.0 1586101 TimTec1_005156 CN(C)CCN(Cc1ccccc1)Cc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K09 compound treatment 0.256 0.0055 0.3 0.2956 1.0 1051443 TimTec1_005157 FC(F)(F)CN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K10 compound treatment 0.41 0.16 8.57 8.5712 1.0 1698764 TimTec1_005158 COc1ccc(NCc2cn3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K11 compound treatment 0.252 0.0015 0.08 0.0806 1.0 3212156 TimTec1_005159 N#CCCN1CCCC2(CCCC2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K12 compound treatment 0.574 0.324 17.38 17.3842 1.0 3212157 TimTec1_005160 O=C/1N=C(S\C1=C/c2cccs2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K13 compound treatment 0.27 0.0195 1.05 1.0479 1.0 1604720 TimTec1_005161 CCc1c(C)nc2ccccc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K14 compound treatment 0.293 0.0425 2.28 2.2839 1.0 3212158 TimTec1_005162 Cc1cc(C)cc(Nc2csc(N/C=N\O)n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K15 compound treatment 0.27 0.0195 1.05 1.0479 1.0 3086348 TimTec1_005163 OC(=O)c1ccccc1NCn2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K16 compound treatment 0.281 0.0305 1.64 1.639 1.0 3212159 TimTec1_005164 Clc1ccc(cc1)C2=CC=C(C#N)C(N2)SCc3nc4ccccc4[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K17 compound treatment 0.253 0.0025 0.13 0.1343 1.0 1472272 TimTec1_005165 CNc1nc(nc(n1)N2CCOCC2)N(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K18 compound treatment 0.314 0.0635 3.41 3.4124 1.0 3086351 TimTec1_005166 CCCC1CCC(CC1)c2ccc(cc2)/C(=N/O)/N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K19 compound treatment 0.354 0.103 5.56 5.5619 1.0 3212160 TimTec1_005167 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K20 compound treatment 0.29 0.0395 2.12 2.1226 1.0 1130551 TimTec1_005168 COc1ccc(cc1)N(C(=O)c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K21 compound treatment 0.53 0.28 15.02 15.0197 1.0 3212161 TimTec1_005169 FC(F)(F)c1ccccc1NC(NC(=O)c2ccco2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K22 compound treatment 0.256 0.0055 0.3 0.2956 1.0 1915266 TimTec1_005170 Cc1cc[n+](CCC(=O)O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K23 mock treatment 0.265 0.0145 0.78 0.7792 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 K24 mock treatment 0.253 0.0025 0.13 0.1343 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L01 compound treatment 0.255 0.0045 0.24 0.2418 1.0 1383984 TimTec1_005171 CCC1=CC(C)(CC)Nc2cc(C)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L02 compound treatment 0.253 0.0025 0.13 0.1343 1.0 1409216 TimTec1_005172 COc1cc(cc(OC)c1OC)C(=O)N(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L03 compound treatment 0.258 0.0075 0.4 0.403 1.0 1273531 TimTec1_005173 OCC(O)C1OC(OCC1O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L04 compound treatment 0.242 -0.0085 -0.46 -0.4568 -1.0 1385587 TimTec1_005174 Cc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3c(C)cccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L05 compound treatment 0.314 0.0635 3.41 3.4124 1.0 3212235 TimTec1_005175 OC(=O)C(Cc1ccc(O)cc1)/N=C/c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L06 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 3086357 TimTec1_005176 COC(=O)c1c(NC(=O)C(F)(F)F)sc2CCCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L07 compound treatment 0.23 -0.0205 -1.1 -1.1016 -1.0 1333937 TimTec1_005177 O=S(=O)(C1CCS(=O)(=O)C1)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L08 compound treatment 0.251 5.0E-4 0.03 0.0269 1.0 1533793 TimTec1_005178 Cc1ccc(NC(=O)C2C(C=CC(C2C(=O)O)c3ccccc3)c4ccccc4)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L09 compound treatment 0.251 5.0E-4 0.03 0.0269 1.0 1611679 TimTec1_005179 COc1ccc(cc1)C(C2=C(O)CCCC2=O)c3cc4OCOc4cc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L10 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 1081231 TimTec1_005180 O=C1N(C(=O)c2nccnc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L11 compound treatment 0.328 0.0775 4.16 4.1647 1.0 1700569 TimTec1_005181 CCOC(=O)C1=C(O)c2ccccc2NC(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L12 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 1371927 TimTec1_005182 Cc1cccc2c(cc(nc12)c3ccccc3)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L13 compound treatment 0.316 0.0655 3.52 3.5198 1.0 3086362 TimTec1_005183 Cc1cc2ncc(nc2cc1C)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L14 compound treatment 0.307 0.0565 3.04 3.0362 1.0 1442595 TimTec1_005184 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(I)cc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L15 compound treatment 0.291 0.0405 2.18 2.1764 1.0 3086440 TimTec1_005185 CCOC(=O)/C(=C(/N)\c1cc2cccc(OC)c2oc1=O)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L16 compound treatment 0.384 0.134 7.17 7.174 1.0 1612648 TimTec1_005186 CC1CCN(Cc2cc3c(cc(=O)oc3c(C)c2O)c4ccccc4)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L17 compound treatment 0.299 0.0485 2.61 2.6063 1.0 3212236 TimTec1_005187 Cn1cnnc1SCc2cccc(CSc3nncn3C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L18 compound treatment 0.289 0.0385 2.07 2.0689 1.0 3086444 TimTec1_005188 CCN(CC)c1ccc(/N=C/c2ccc3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L19 compound treatment 0.323 0.0725 3.9 3.896 1.0 1589064 TimTec1_005189 Clc1c(sc2ccccc12)C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L20 compound treatment 0.489 0.238 12.82 12.8165 1.0 3212237 TimTec1_005190 CC1SC(=NNC1=O)/N=C/c2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L21 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 3086447 TimTec1_005191 CC(NC(CC(=O)c1ccc(F)cc1)C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L22 compound treatment 0.548 0.297 15.99 15.987 1.0 1451936 TimTec1_005192 CCCc1cc(=O)oc2cc(OCc3ccccc3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L23 mock treatment 0.252 0.0015 0.08 0.0806 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 L24 mock treatment 0.233 -0.0175 -0.94 -0.9404 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M01 compound treatment 0.235 -0.0155 -0.83 -0.8329 -1.0 3086449 TimTec1_005193 CCOC(=O)CN1CCN(CC1)C=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M02 compound treatment 0.478 0.228 12.23 12.2254 1.0 3212238 TimTec1_005194 O=C(/C=C\Nc1cccc(N/C=C\C(=O)c2ccccc2)c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M03 compound treatment 0.287 0.0365 1.96 1.9614 1.0 1445055 TimTec1_005195 Cc1ccccc1OC(=O)Cn2c(=O)sc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M04 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1718720 TimTec1_005196 CN1CCN(Cc2coc3ccccc3c2=O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M05 compound treatment 0.243 -0.0075 -0.4 -0.403 -1.0 1415720 TimTec1_005197 OCC1Sc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M06 compound treatment 0.237 -0.0135 -0.73 -0.7255 -1.0 1643885 TimTec1_005198 NC(=O)C1CCN(Cc2ccc(Cl)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M07 compound treatment 0.263 0.0125 0.67 0.6717 1.0 3212239 TimTec1_005199 COc1ccc2c3CC[C@](C)(CCC(=O)O)C(=O)c3ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M08 compound treatment 0.259 0.0085 0.46 0.4568 1.0 3086453 TimTec1_005200 Cc1ccc(C(=O)Sc2nc(N)c(C#N)cc2C#N)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M09 compound treatment 0.519 0.269 14.43 14.4286 1.0 1212803 TimTec1_005201 CCOc1ccc2c(cc(=O)oc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M10 compound treatment 0.407 0.157 8.41 8.41 1.0 3086455 TimTec1_005202 COc1ccc(cc1)c2cc(nc(=O)[nH]2)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M11 compound treatment 0.244 -0.0065 -0.35 -0.3493 -1.0 1222652 TimTec1_005203 CCc1cc2OCCOc2cc1C(=O)c3ccc(I)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M12 compound treatment 0.259 0.0085 0.46 0.4568 1.0 1107292 TimTec1_005204 CCC1SC2=NCCN2C1(O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M13 compound treatment 0.261 0.0105 0.56 0.5642 1.0 1431781 TimTec1_005205 CC1(C)CC2(CCCN(CCC(O)(c3ccccc3)c4ccccc4)C2)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M14 compound treatment 0.46 0.209 11.26 11.2581 1.0 1622469 TimTec1_005206 CCCCn1c(nn(c1=O)S(=O)(=O)c2ccc(Br)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M15 compound treatment 0.257 0.0065 0.35 0.3493 1.0 1265308 TimTec1_005207 OC(=O)c1ccccc1C(=O)Nc2cccc3ncccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M16 compound treatment 0.456 0.205 11.04 11.0431 1.0 3086459 TimTec1_005208 CSC1=Nc2ccccc2CN1c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M17 compound treatment 0.26 0.0095 0.51 0.5105 1.0 3086461 TimTec1_005209 O=C(Nc1nc[nH]n1)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M18 compound treatment 0.297 0.0465 2.5 2.4988 1.0 1609905 TimTec1_005210 CCCC1CCC(CC1)c2ccc(cc2)C(=O)CCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M19 compound treatment 0.256 0.0055 0.3 0.2956 1.0 3212240 TimTec1_005211 Cc1ccc(cc1)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M20 compound treatment 0.256 0.0055 0.3 0.2956 1.0 3085449 TimTec1_005212 CC[C@@]1(C)N[C@@H](CS1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M21 compound treatment 0.52 0.27 14.48 14.4824 1.0 1601693 TimTec1_005213 O=C(NC(Nc1cccc2ccccc12)C(=O)c3ccccc3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M22 compound treatment 0.456 0.205 11.04 11.0431 1.0 1269343 TimTec1_005214 CC(CC(=O)c1ccccc1)CC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M23 mock treatment 0.255 0.0045 0.24 0.2418 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 M24 mock treatment 0.258 0.0075 0.4 0.403 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N01 compound treatment 0.377 0.127 6.8 6.7978 1.0 3085453 TimTec1_005215 Cc1cc(C)c(CC2C(=O)c3ccccc3C2=O)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N02 compound treatment 0.424 0.173 9.32 9.3235 1.0 1524336 TimTec1_005216 O=C(NCCc1nc2ccccc2[nH]1)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N03 compound treatment 0.338 0.0875 4.7 4.7021 1.0 1139245 TimTec1_005217 O=C(Cc1ccccc1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N04 compound treatment 0.482 0.232 12.44 12.4403 1.0 1718136 TimTec1_005218 O=c1oc2ccccc2cc1c3nnc(o3)c4cccc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N05 compound treatment 0.245 -0.0055 -0.3 -0.2956 -1.0 3085456 TimTec1_005219 CC1(C)CC(=O)C2C(=Nc3ccccc3N=C2c4ccccc4)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N06 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 1256766 TimTec1_005220 CC1N(c2cccc(C)c2)C3(CCCCC3)SC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N07 compound treatment 0.253 0.0025 0.13 0.1343 1.0 1496277 TimTec1_005221 NC(=O)C(C1CCS(=O)(=O)C1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N08 compound treatment 0.244 -0.0065 -0.35 -0.3493 -1.0 1400156 TimTec1_005222 NNC(=O)C1CCCN1S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N09 compound treatment 0.442 0.192 10.29 10.2908 1.0 1525056 TimTec1_005223 COc1ccc(cc1)C2C3C(=O)CCCC3(O)Oc4cc5OCOc5cc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N10 compound treatment 0.528 0.278 14.91 14.9123 1.0 1231285 TimTec1_005224 CCN(CC)c1ccc2cc(c3ncc(o3)c4ccc(F)cc4)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N11 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 3212241 TimTec1_005225 COc1cc2CCN(C)[C@H](Cc3ccc(O)cc3)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N12 compound treatment 0.274 0.0235 1.26 1.2628 1.0 1135918 TimTec1_005226 Oc1ccccc1C2=Nc3ncnn3C(C2)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N13 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 3212242 TimTec1_005227 CCC[n+]1ccc(cc1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N14 compound treatment 0.296 0.0455 2.45 2.4451 1.0 1154608 TimTec1_005228 CC(C)c1ccc(OC(=O)C(C)N2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N15 compound treatment 0.272 0.0215 1.16 1.1554 1.0 3212243 TimTec1_005229 CCOC(=O)/C(=C(/N)\c1cc2cc(Br)cc(Br)c2oc1=O)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N16 compound treatment 0.261 0.0105 0.56 0.5642 1.0 1059298 TimTec1_005230 Cc1cc2oc(=O)c3CCCCc3c2c(O)c1CN4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N17 compound treatment 0.244 -0.0065 -0.35 -0.3493 -1.0 1365174 TimTec1_005231 NC(=O)CNC(=O)c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N18 compound treatment 0.255 0.0045 0.24 0.2418 1.0 3085464 TimTec1_005232 CC(N1C(=O)CCC1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N19 compound treatment 0.276 0.0255 1.37 1.3703 1.0 3212244 TimTec1_005233 COC(=O)c1cc(Br)ccc1OC(=O)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N20 compound treatment 0.485 0.234 12.6 12.6015 1.0 3085466 TimTec1_005234 Oc1ccccc1/C=N/C2=NNC(=O)CS2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N21 compound treatment 0.267 0.0165 0.89 0.8867 1.0 3212245 TimTec1_005235 Cc1ccc(/C=C/C(=O)Nc2ccccc2C(F)(F)F)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N22 compound treatment 0.328 0.0775 4.16 4.1647 1.0 1411087 TimTec1_005236 CCOC(=O)Cc1cc(=O)oc2cc(OCC)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N23 mock treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 N24 mock treatment 0.239 -0.0115 -0.62 -0.618 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O01 compound treatment 0.261 0.0105 0.56 0.5642 1.0 3212318 TimTec1_005237 C=CCOC(=O)OCn1c(=O)sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O02 compound treatment 0.254 0.0035 0.19 0.1881 1.0 3212319 TimTec1_005238 CCCCN1N=C(C)CC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O03 compound treatment 0.302 0.0515 2.77 2.7675 1.0 3212320 TimTec1_005239 O=C(Cn1c(=O)sc2ccccc12)OC(C(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O04 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 1379879 TimTec1_005240 CN1CCN(Cc2ccc(NC(=O)C)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O05 compound treatment 0.256 0.0055 0.3 0.2956 1.0 1721138 TimTec1_005241 CC1CN(CC2COC(C)(C)O2)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O06 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 1672440 TimTec1_005242 NC(=O)C1CCN(CC2CCC=CC2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O07 compound treatment 0.411 0.161 8.62 8.6249 1.0 1624424 TimTec1_005243 COc1cc2c3CCc4cn[nH]c4-c3ccc2c(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O08 compound treatment 0.266 0.0155 0.83 0.8329 1.0 1736587 TimTec1_005244 Fc1ccc(cc1)C(=O)Oc2ccccc2c3cnc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O09 compound treatment 0.473 0.223 11.96 11.9567 1.0 1502476 TimTec1_005245 CC(C)C(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4)coc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O10 compound treatment 0.258 0.0075 0.4 0.403 1.0 1214549 TimTec1_005246 COc1cc(ccc1O)C2CS(=O)(=O)CS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O11 compound treatment 0.254 0.0035 0.19 0.1881 1.0 1679192 TimTec1_005247 O=C(c1cccs1)c2ccc3OCCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O12 compound treatment 0.251 5.0E-4 0.03 0.0269 1.0 3086118 TimTec1_005248 FC(F)(F)c1ccc2c(Cl)ccnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O13 compound treatment 0.289 0.0385 2.07 2.0689 1.0 1449875 TimTec1_005249 CN(C)CCC(=O)c1ccc2OCCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O14 compound treatment 0.32 0.0695 3.73 3.7348 1.0 3086120 TimTec1_005250 S=c1[nH]c(ccc1C#N)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O15 compound treatment 0.268 0.0175 0.94 0.9404 1.0 1687305 TimTec1_005251 O=C1N(C(=O)c2ccccc12)c3ccc4ncccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O16 compound treatment 0.251 5.0E-4 0.03 0.0269 1.0 1675695 TimTec1_005252 CN1C2OC(=C(C#N)C(C2C(=O)N(C)C1=O)c3cccc(Br)c3)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O17 compound treatment 0.284 0.0335 1.8 1.8002 1.0 3086122 TimTec1_005253 O=C(/C=C/c1ccccc1)N2C(COC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O18 compound treatment 0.251 5.0E-4 0.03 0.0269 1.0 3212321 TimTec1_005254 CCN(CC)[P+](NC(=O)c1ccccc1)(N(CC)CC)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O19 compound treatment 0.284 0.0335 1.8 1.8002 1.0 3212322 TimTec1_005255 O=C(NC1CCCCC1)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O20 compound treatment 0.298 0.0475 2.55 2.5526 1.0 3086125 TimTec1_005256 O[C@@H]1CO[C@@H](Nc2ccccc2)[C@H](O)[C@H]1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O21 compound treatment 0.248 -0.0025 -0.13 -0.1343 -1.0 1457665 TimTec1_005257 OP(=O)(c1nc2ccccc2n1CC=C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O22 compound treatment 0.25 -5.0E-4 -0.03 -0.0269 -1.0 1597857 TimTec1_005258 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O23 mock treatment 0.257 0.0065 0.35 0.3493 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 O24 mock treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P01 compound treatment 0.249 -0.0015 -0.08 -0.0806 -1.0 3212323 TimTec1_005259 C[n+]1cn(NC(=O)c2ccc(cc2)C(=O)ON3C(=O)CCC3=O)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P02 compound treatment 0.235 -0.0155 -0.83 -0.8329 -1.0 3212324 TimTec1_005260 OC(=O)C(Cc1ccccc1)NCc2c(O)ccc3c4CCCCc4c(=O)oc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P03 compound treatment 0.469 0.219 11.74 11.7417 1.0 1665007 TimTec1_005261 COc1ccc(CCC(=O)c2ccc3OCCOc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P04 compound treatment 0.312 0.0615 3.3 3.3049 1.0 3212325 TimTec1_005262 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P05 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 3086129 TimTec1_005263 Oc1ccc(Cl)cc1/C=N/CCc2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P06 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 1176935 TimTec1_005264 CC(=O)Nc1cccc(NC(=O)N2CCOCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P07 compound treatment 0.233 -0.0175 -0.94 -0.9404 -1.0 3086130 TimTec1_005265 CN(N)P(=O)(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P08 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 3212326 TimTec1_005266 OC(=O)c1ccccc1C(=O)Nc2ccc(/C=C/c3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P09 compound treatment 0.239 -0.0115 -0.62 -0.618 -1.0 1689960 TimTec1_005267 COc1ccc(cc1)C2C(C)C(C)(Oc3cc4OCOc4cc23)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P10 compound treatment 0.279 0.0285 1.53 1.5315 1.0 3212327 TimTec1_005268 CC(C)c1ccc(cc1)C2C(=C(N)SC(=C2C#N)N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P11 compound treatment 0.279 0.0285 1.53 1.5315 1.0 1088185 TimTec1_005269 COc1cc2C=CN(C(C#N)c2cc1OC)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P12 compound treatment 0.42 0.17 9.11 9.1086 1.0 1306739 TimTec1_005270 CC(C)CNc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P13 compound treatment 0.247 -0.0035 -0.19 -0.1881 -1.0 1251200 TimTec1_005271 O=C1CC(N2CCCc3ccccc23)C(=O)N1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P14 compound treatment 0.372 0.122 6.53 6.5292 1.0 1588848 TimTec1_005272 Cc1ccc(CNc2nc3n(C)c(=O)[nH]c(=O)c3n2Cc4ccccc4C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P15 compound treatment 0.241 -0.0095 -0.51 -0.5105 -1.0 1071878 TimTec1_005273 COc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P16 compound treatment 0.352 0.102 5.45 5.4544 1.0 1718803 TimTec1_005274 Cc1cc(OC(=O)CNC(=O)OCc2ccccc2)cc3oc(=O)c4ccccc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P17 compound treatment 0.246 -0.0045 -0.24 -0.2418 -1.0 1656249 TimTec1_005275 CCC(Cc1cccc(O)c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P18 compound treatment 0.286 0.0355 1.91 1.9077 1.0 1501431 TimTec1_005276 Brc1ccc(cc1)N2C(=O)CC(Nc3c[nH]c(=O)[nH]c3=O)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P19 compound treatment 0.28 0.0295 1.59 1.5853 1.0 3212328 TimTec1_005277 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P20 compound treatment 0.483 0.233 12.49 12.4941 1.0 3086198 TimTec1_005278 Oc1ccccc1/C=N/C2=NNC(=CS2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P21 compound treatment 0.323 0.0725 3.9 3.896 1.0 3086200 TimTec1_005279 N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P22 compound treatment 0.368 0.117 6.31 6.3142 1.0 1555180 TimTec1_005280 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)Oc2cc3oc(=O)c(Cl)c(C)c3cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P23 mock treatment 0.232 -0.0185 -0.99 -0.9942 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2077 P24 mock treatment 0.253 0.0025 0.13 0.1343 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A01 compound treatment 0.294 0.0439 2.36 2.3611 1.0 1179025 TimTec1_005281 Cc1c(OCC(=O)O)ccc2c(cc(=O)oc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A02 compound treatment 0.226 -0.0241 -1.29 -1.2931 -1.0 3212329 TimTec1_005282 C(=N/c1nccs1)\c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A03 compound treatment 0.218 -0.0321 -1.72 -1.723 -1.0 1341807 TimTec1_005283 CCc1cc2c(=O)c(c3nc4ccccc4s3)c(C)oc2c(CN(C)C)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A04 compound treatment 0.484 0.234 12.57 12.5713 1.0 3086205 TimTec1_005284 Cc1cc(C)c(C#N)c(SCC(=O)c2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A05 compound treatment 0.481 0.231 12.41 12.4101 1.0 1015158 TimTec1_005285 COC(=O)c1ccc(NN)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A06 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1579854 TimTec1_005286 Nc1nc(cs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A07 compound treatment 0.226 -0.0241 -1.29 -1.2931 -1.0 3086207 TimTec1_005287 CC(C)c1cc(I)c(C)cc1OC(=O)NC(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A08 compound treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 1603281 TimTec1_005288 O=C(NCc1ccccc1)C2CCCN2C(=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A09 compound treatment 0.468 0.218 11.71 11.7115 1.0 1494738 TimTec1_005289 O=C(Cn1c(=S)[nH]c2ccccc12)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A10 compound treatment 0.322 0.0719 3.87 3.8658 1.0 1405927 TimTec1_005290 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCC2(OC3C=C2)C4C3C(=O)N(C4=O)c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A11 compound treatment 0.476 0.226 12.14 12.1414 1.0 1153776 TimTec1_005291 Cc1c(CCC(=O)NN)c(C)n2c3ccccc3nc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A12 compound treatment 0.226 -0.0241 -1.29 -1.2931 -1.0 3086211 TimTec1_005292 COc1cc(/C=N/Cc2ccco2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A13 compound treatment 0.312 0.0619 3.33 3.3284 1.0 1733511 TimTec1_005293 CC1(C)CC(CCO1)C(=O)COc2ccc3ccc(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A14 compound treatment 0.243 -0.00706 -0.38 -0.3795 -1.0 1139337 TimTec1_005294 C(Oc1ccccc1OCc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A15 compound treatment 0.37 0.12 6.45 6.4452 1.0 3212403 TimTec1_005295 O=C(NC(SC1=NCCS1)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A16 compound treatment 0.237 -0.0131 -0.7 -0.702 -1.0 3086214 TimTec1_005296 CC(C)(CCN1CCOCC1)NC(=O)C=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A17 compound treatment 0.455 0.205 11.01 11.0129 1.0 1301247 TimTec1_005297 COc1cc2c(C(=O)O)c(C)oc2cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A18 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1734603 TimTec1_005298 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccoc3)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A19 compound treatment 0.341 0.0909 4.89 4.8868 1.0 3212404 TimTec1_005299 CN1CCc2[nH]c(=S)c(C#N)c(c3ccccc3)c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A20 compound treatment 0.291 0.0409 2.2 2.1999 1.0 3086280 TimTec1_005300 COC(=O)/C=C\1/Nc2ccccc2SC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A21 compound treatment 0.463 0.213 11.44 11.4428 1.0 3212405 TimTec1_005301 Cc1cccc(NCN2C(=O)S/C(=C\c3cccc(F)c3)/C2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A22 compound treatment 0.584 0.334 17.95 17.9451 1.0 1421857 TimTec1_005302 COc1ccc(cc1OC)C(=O)Nc2nnc(o2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A23 mock treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 A24 mock treatment 0.261 0.0109 0.59 0.5878 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B01 compound treatment 0.237 -0.0131 -0.7 -0.702 -1.0 3212406 TimTec1_005303 CC(C)P(C(C)C)c1ccc(C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B02 compound treatment 0.379 0.129 6.93 6.9288 1.0 3212407 TimTec1_005304 CC(C)COc1ccc(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B03 compound treatment 0.41 0.16 8.59 8.5947 1.0 1371685 TimTec1_005305 O=C(NCc1cccnc1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B04 compound treatment 0.274 0.0239 1.29 1.2864 1.0 3086285 TimTec1_005306 COc1cc(OC)c(/C=N/c2ccccc2)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B05 compound treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 1138064 TimTec1_005307 OP(=O)(CCN1CCCC1=O)CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B06 compound treatment 0.422 0.172 9.24 9.2396 1.0 1556230 TimTec1_005308 COc1ccc2CCC(C(=O)c2c1)C3(O)C(=O)Nc4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B07 compound treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 3086287 TimTec1_005309 CCC(NC(=O)Oc1ccc2ccccc2c1)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B08 compound treatment 0.302 0.0519 2.79 2.791 1.0 1141795 TimTec1_005310 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc4ccccc4C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B09 compound treatment 0.251 9.37E-4 0.05 0.0504 1.0 3086290 TimTec1_005311 Cc1ccc2cccc(SCc3ccc(Br)cc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B10 compound treatment 0.237 -0.0131 -0.7 -0.702 -1.0 1716446 TimTec1_005312 Clc1cc(NC2CCCCC2)c3C(=O)c4ccccc4-c5onc1c53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B11 compound treatment 0.4 0.15 8.06 8.0573 1.0 3212408 TimTec1_005313 COc1cc(ccc1O)c2nc3ccccn3c2/N=C/c4cccc(Cl)c4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B12 compound treatment 0.243 -0.00706 -0.38 -0.3795 -1.0 1140826 TimTec1_005314 OC1(CCN([C@@H]2CCCC[C@@H]21)C(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B13 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1456412 TimTec1_005315 CN(CP(=O)(O)CCc1ccccc1)C=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B14 compound treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 1674110 TimTec1_005316 Cc1ccc(C)c(NC(=O)C2CC(O)CN2C(=O)OC(C)(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B15 compound treatment 0.244 -0.00606 -0.33 -0.3258 -1.0 3212409 TimTec1_005317 CCN(CC)S(=O)(=O)c1ncn[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B16 compound treatment 0.532 0.282 15.15 15.1507 1.0 3212410 TimTec1_005318 Oc1ccccc1/C=C\2/S\C(=N/c3ccccc3)\N(Cc4ccccc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B17 compound treatment 0.298 0.0479 2.58 2.5761 1.0 1238350 TimTec1_005319 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Oc2cccc(c2)c3cnc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B18 compound treatment 0.24 -0.0101 -0.54 -0.5407 -1.0 1373281 TimTec1_005320 OC(C#CC(O)(c1ccccc1)c2ccccc2)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B19 compound treatment 0.371 0.121 6.5 6.4989 1.0 1306989 TimTec1_005321 COc1ccc2N(Cn3nc(c4ccccc4)n(c5ccccc5)c3=S)CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B20 compound treatment 0.346 0.0959 5.16 5.1555 1.0 1546728 TimTec1_005322 O=C(c1ccccc1)c2nc3ccccc3[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B21 compound treatment 0.441 0.191 10.26 10.2606 1.0 3086367 TimTec1_005323 COC(=O)C1=C(C)N(/C(=C/c2cccc3ccccc23)/C1=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B22 compound treatment 0.328 0.0779 4.19 4.1882 1.0 3086369 TimTec1_005324 O=C(/C=C/c1ccco1)C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B23 mock treatment 0.248 -0.00206 -0.11 -0.1108 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 B24 mock treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C01 compound treatment 0.384 0.134 7.2 7.1975 1.0 1366978 TimTec1_005325 Cc1cc(=O)oc2cc(OC(=O)C3CCCN3C(=O)OC(C)(C)C)c(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C02 compound treatment 0.277 0.0269 1.45 1.4476 1.0 3086371 TimTec1_005326 NC1=C(C#N)C(c2ccccc2)c3ccc(N)cc3O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C03 compound treatment 0.334 0.0839 4.51 4.5106 1.0 1640630 TimTec1_005327 CCN(CC)Cc1c(O)ccc2cc(c3nc4ccccc4[nH]3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C04 compound treatment 0.21 -0.0401 -2.15 -2.1529 -1.0 1378375 TimTec1_005328 O=C(Oc1ccccc1OC(=O)C2C3CCCCC23)C4C5CCCCC45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C05 compound treatment 0.266 0.0159 0.86 0.8564 1.0 1495247 TimTec1_005329 Brc1ccc(OCC(=O)Nc2ccccc2N3C(=O)c4ccccc4C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C06 compound treatment 0.337 0.0869 4.67 4.6718 1.0 3212411 TimTec1_005330 C(=N/c1ccc2[nH]c(nc2c1)c3ccccc3)\c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C07 compound treatment 0.294 0.0439 2.36 2.3611 1.0 3212412 TimTec1_005331 CCOC(=O)NC1(N/C(=N/c2ccccc2)/N3CCOCC3)Oc4ccccc4O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C08 compound treatment 0.303 0.0529 2.84 2.8448 1.0 1281134 TimTec1_005332 COc1ccccc1NC(=O)C2CC2(c3ccc(C)cc3)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C09 compound treatment 0.309 0.0589 3.17 3.1672 1.0 1467004 TimTec1_005333 Cc1cc(C)c(C(=O)Cn2c(=S)[nH]c3ccccc23)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C10 compound treatment 0.476 0.226 12.14 12.1414 1.0 3086377 TimTec1_005334 COc1ccc(/C=N/CCN2Cc3ccccc3C2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C11 compound treatment 0.426 0.176 9.45 9.4545 1.0 1653534 TimTec1_005335 CCOC(=O)CCc1c(C)c(C#N)c2nc3ccccc3n2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C12 compound treatment 0.47 0.22 11.82 11.819 1.0 3086379 TimTec1_005336 Cc1cc(=O)oc2cc(OC(=O)/C=C/c3ccccc3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C13 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 3212413 TimTec1_005337 CC(C)NC(=O)n1cc(F)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C14 compound treatment 0.261 0.0109 0.59 0.5878 1.0 3086381 TimTec1_005338 CC(C)COc1ccccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C15 compound treatment 0.457 0.207 11.12 11.1204 1.0 1498433 TimTec1_005339 O=C(NC(OCc1ccccc1)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C16 compound treatment 0.271 0.0209 1.13 1.1251 1.0 3212414 TimTec1_005340 CN(C(=O)C)c1ccc(/N=C\2/C(=O)Nc3ccc(C)c(Br)c23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C17 compound treatment 0.251 9.37E-4 0.05 0.0504 1.0 3086384 TimTec1_005341 C1Cc2c(C1)c3ccccc3n2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C18 compound treatment 0.569 0.319 17.14 17.139 1.0 1222403 TimTec1_005342 Nc1c(sc2snc(SCC(=O)c3ccccc3)c12)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C19 compound treatment 0.308 0.0579 3.11 3.1134 1.0 3086386 TimTec1_005343 CC(C)(C)NC(=O)CSc1nc(N)c(C#N)cc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C20 compound treatment 0.257 0.00694 0.37 0.3728 1.0 1290278 TimTec1_005344 COC(=O)C(CCCN1C(=O)c2ccccc2C1=O)(NC(=O)C)c3nn[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C21 compound treatment 0.38 0.13 6.98 6.9826 1.0 3086388 TimTec1_005345 COc1ccc(cc1)c2nc3cc(/N=C/c4cccc(OC)c4O)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C22 compound treatment 0.277 0.0269 1.45 1.4476 1.0 3212415 TimTec1_005346 COc1ccc(O)c(/C=N/c2cc(ccc2Oc3ccccc3)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C23 mock treatment 0.263 0.0129 0.7 0.6952 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 C24 mock treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D01 compound treatment 0.243 -0.00706 -0.38 -0.3795 -1.0 1377147 TimTec1_005347 CCC1=NN(C(=O)c2ccccc2F)C(O)(C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D02 compound treatment 0.241 -0.00906 -0.49 -0.487 -1.0 1581632 TimTec1_005348 OC(=O)CCC(=O)N(Cc1ccco1)C2CC(=O)N(C2=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D03 compound treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 1159067 TimTec1_005349 CC12C3CC(C=C3)C2C(=O)N(C1=O)c4cccc(c4)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D04 compound treatment 0.409 0.159 8.54 8.541 1.0 3086466 TimTec1_005350 OCCn/1c(cs\c1=N/c2ccccc2)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D05 compound treatment 0.506 0.256 13.75 13.7535 1.0 1557266 TimTec1_005351 Clc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D06 compound treatment 0.498 0.248 13.32 13.3236 1.0 3212725 TimTec1_005352 OC(=O)c1ccc(cc1)N2C(=O)CC(SC(=N)N3N=C(CC3c4ccccc4)c5ccccc5)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D07 compound treatment 0.282 0.0319 1.72 1.7163 1.0 3086469 TimTec1_005353 O=C(CSc1ncn[nH]1)OCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D08 compound treatment 0.585 0.335 18.0 17.9988 1.0 3086470 TimTec1_005354 CCN(CC)c1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D09 compound treatment 0.233 -0.0171 -0.92 -0.9169 -1.0 1301370 TimTec1_005355 Cc1cc(C)cc(c1)N2C(Nc3ccccc3C2=O)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D10 compound treatment 0.313 0.0629 3.38 3.3821 1.0 3086472 TimTec1_005356 N/C(=C\C(=O)c1c(O)c(F)c(F)c(F)c1F)/C(=O)[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D11 compound treatment 0.254 0.00394 0.21 0.2116 1.0 1471806 TimTec1_005357 Fc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D12 compound treatment 0.268 0.0179 0.96 0.9639 1.0 3212726 TimTec1_005358 CCCC1=C(C(C(=C(N)O1)C#N)c2ccccc2OC)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D13 compound treatment 0.4 0.15 8.06 8.0573 1.0 3086475 TimTec1_005359 Fc1ccc(/C=C/2\CN(Cc3ccccc3)C/C(=C/c4ccc(F)cc4)/C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D14 compound treatment 0.248 -0.00206 -0.11 -0.1108 -1.0 3212727 TimTec1_005360 CN1C(=O)/C(=C\C=C\c2ccccc2Cl)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D15 compound treatment 0.343 0.0929 4.99 4.9943 1.0 1327468 TimTec1_005361 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3sc4CCCCCc4c3C#N)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D16 compound treatment 0.526 0.276 14.83 14.8283 1.0 1533582 TimTec1_005362 CCCn1c2ccccc2c3nnc(SCN4C(=O)c5ccccc5C4=O)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D17 compound treatment 0.497 0.247 13.27 13.2699 1.0 1465950 TimTec1_005363 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D18 compound treatment 0.267 0.0169 0.91 0.9102 1.0 1384915 TimTec1_005364 Clc1cccc(NC(=O)COC(=O)c2ccc(cc2)N3C(=O)CCC3=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D19 compound treatment 0.28 0.0299 1.61 1.6088 1.0 1450022 TimTec1_005365 COc1ccc2N(Cn3nc(COc4ccccc4)n(C)c3=S)CCCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D20 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1291038 TimTec1_005366 CCC(O)C#CCN1CCN(C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D21 compound treatment 0.301 0.0509 2.74 2.7373 1.0 1912707 TimTec1_005367 CC(C)(O)C(=O)/C=C/c1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D22 compound treatment 0.248 -0.00206 -0.11 -0.1108 -1.0 1025952 TimTec1_005368 Cc1cc(Cc2ccc(N)c(C)c2)ccc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D23 mock treatment 0.249 -0.00106 -0.06 -0.0571 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 D24 mock treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E01 compound treatment 0.23 -0.0201 -1.08 -1.0781 -1.0 2102259 TimTec1_005369 CC(C)CC(NCc1c(O)ccc2c(C)cc(=O)oc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E02 compound treatment 0.281 0.0309 1.66 1.6625 1.0 3086481 TimTec1_005370 O=C1NC(=O)/C(=C\c2ccccc2)/N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E03 compound treatment 0.236 -0.0141 -0.76 -0.7557 -1.0 1012035 TimTec1_005371 CN1CCC(O)(C(C1)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E04 compound treatment 0.262 0.0119 0.64 0.6415 1.0 3212728 TimTec1_005372 CCc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E05 compound treatment 0.334 0.0839 4.51 4.5106 1.0 1629849 TimTec1_005373 CC(C)CN(CC(C)C)C(=O)CCN1C(=O)c2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E06 compound treatment 0.277 0.0269 1.45 1.4476 1.0 3212729 TimTec1_005374 CSc1nc2sc3COC(C)(C)Cc3c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E07 compound treatment 0.229 -0.0211 -1.13 -1.1319 -1.0 3212730 TimTec1_005375 CC(C)c1ccc(C)cc1OC(=O)NC2(Oc3ccc(Cl)cc3O2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E08 compound treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 1308284 TimTec1_005376 Cc1ccc(cc1)N2CC(=O)SC32CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E09 compound treatment 0.549 0.299 16.06 16.0643 1.0 3085473 TimTec1_005377 COc1ccc(cc1)C2=CN3C(=O)CSC3=NN2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E10 compound treatment 0.254 0.00394 0.21 0.2116 1.0 1639246 TimTec1_005378 CCOC(=O)c1c(CN2CCOCC2)oc3ccc(OC)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E11 compound treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 3085475 TimTec1_005379 CC(=C)Cn1c(S)nc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E12 compound treatment 0.409 0.159 8.54 8.541 1.0 3212731 TimTec1_005380 Cc1ccc(/C=C/2\OC(=O)C=C2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E13 compound treatment 0.327 0.0769 4.13 4.1345 1.0 1303286 TimTec1_005381 CCc1cc2c(=O)c(coc2cc1O)c3nc(C)cs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E14 compound treatment 0.257 0.00694 0.37 0.3728 1.0 3085477 TimTec1_005382 O=C(CSc1nc(ccc1C#N)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E15 compound treatment 0.282 0.0319 1.72 1.7163 1.0 3212732 TimTec1_005383 COc1ccccc1N2CCN(CC2)/N=C/c3sccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E16 compound treatment 0.252 0.00194 0.1 0.1041 1.0 1527733 TimTec1_005384 Nc1nonc1C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E17 compound treatment 0.243 -0.00706 -0.38 -0.3795 -1.0 3212733 TimTec1_005385 O=C1N([C@H]2CC(=O)[C@@H]3OCC2O3)S(=O)(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E18 compound treatment 0.3 0.0499 2.68 2.6835 1.0 1204206 TimTec1_005386 CC(C)(C)NC(=O)CSc1nsc(SCC(=O)NC(C)(C)C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E19 compound treatment 0.536 0.286 15.37 15.3657 1.0 3212734 TimTec1_005387 NC1=C(C#N)C(C(=c2s/c(=C\c3ccco3)/c(=O)n12)C#N)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E20 compound treatment 0.276 0.0259 1.39 1.3938 1.0 1594563 TimTec1_005388 OC(=O)CCC(=O)Nc1ccccc1C#Cc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E21 compound treatment 0.394 0.144 7.73 7.7349 1.0 3212735 TimTec1_005389 COc1cccc(/C=N/c2ccc(cc2)c3nc4ccc(C)cc4o3)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E22 compound treatment 0.299 0.0489 2.63 2.6298 1.0 3085483 TimTec1_005390 C/C=C/c1c(C)nc2sc(C#N)c(N)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E23 mock treatment 0.26 0.00994 0.53 0.534 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 E24 mock treatment 0.259 0.00894 0.48 0.4803 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F01 compound treatment 0.33 0.0799 4.3 4.2957 1.0 1199396 TimTec1_005391 O=C(NCc1cccs1)c2cccc(c2)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F02 compound treatment 0.456 0.206 11.07 11.0667 1.0 1438185 TimTec1_005392 N#Cc1ccc(cc1C#N)n2c(nnc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F03 compound treatment 0.289 0.0389 2.09 2.0924 1.0 1602974 TimTec1_005393 Cc1cc(C)c2oc(nc2c1)c3ccc(N)cc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F04 compound treatment 0.235 -0.0151 -0.81 -0.8094 -1.0 1565318 TimTec1_005394 COC(=O)C(C(Nc1ccccc1)c2ccccc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F05 compound treatment 0.369 0.119 6.39 6.3915 1.0 3085487 TimTec1_005395 COC(=O)CSc1nc(C)nc2c3ccccc3oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F06 compound treatment 0.259 0.00894 0.48 0.4803 1.0 3212736 TimTec1_005396 CN(C)c1ccc(/C=N/c2ccc3[nH]c(=O)[nH]c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F07 compound treatment 0.243 -0.00706 -0.38 -0.3795 -1.0 3085489 TimTec1_005397 CN(C)C(=O)/C(=C/c1ccc(F)cc1)/NC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F08 compound treatment 0.32 0.0699 3.76 3.7583 1.0 3212737 TimTec1_005398 N#Cc1c(NCSCc2ccccc2)sc3CCCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F09 compound treatment 0.232 -0.0181 -0.97 -0.9706 -1.0 1212031 TimTec1_005399 CC(C)(C)C(=O)Nc1cc(NC(=O)C(C)(C)C)cc(c1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F10 compound treatment 0.429 0.179 9.62 9.6157 1.0 1476455 TimTec1_005400 CC(CS(=O)(=O)c1ccccc1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F11 compound treatment 0.495 0.245 13.16 13.1624 1.0 1295263 TimTec1_005401 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F12 compound treatment 0.4 0.15 8.06 8.0573 1.0 1158028 TimTec1_005402 C(Sc1nnc2c3ccccc3n(Cc4ccccc4)c2n1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F13 compound treatment 0.239 -0.0111 -0.59 -0.5945 -1.0 3086060 TimTec1_005403 CCC(NC(=O)OC1CCCCC1C)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F14 compound treatment 0.336 0.0859 4.62 4.6181 1.0 3212738 TimTec1_005404 CN1C(=O)S/C(=C/c2cc(C)n(c2C)c3ccccc3)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F15 compound treatment 0.23 -0.0201 -1.08 -1.0781 -1.0 1322720 TimTec1_005405 CCOC(=O)c1c(CSc2ccccc2)oc3ccc(O)c(CN(C)C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F16 compound treatment 0.437 0.187 10.05 10.0456 1.0 1183235 TimTec1_005406 Cc1ccc2nc(NC(=O)C(Cc3ccccc3)NC(=O)OCc4ccccc4)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F17 compound treatment 0.252 0.00194 0.1 0.1041 1.0 1662436 TimTec1_005407 Nc1nonc1n2nnc(C(=O)N3CCCC3)c2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F18 compound treatment 0.263 0.0129 0.7 0.6952 1.0 1606341 TimTec1_005408 COC(=O)C1=C(c2ccccc2)S(=O)(=O)CCN1C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F19 compound treatment 0.557 0.307 16.49 16.4942 1.0 1282067 TimTec1_005409 COC(=O)c1ccc(NC(=O)CSc2nnc(N)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F20 compound treatment 0.283 0.0329 1.77 1.77 1.0 3086064 TimTec1_005410 CSC1=NC(C)(C)Cc2c(C)cccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F21 compound treatment 0.325 0.0749 4.03 4.027 1.0 1037267 TimTec1_005411 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F22 compound treatment 0.404 0.154 8.27 8.2723 1.0 1160915 TimTec1_005412 Cc1cccc(c1C)n2c(CSc3nc4ccccc4[nH]3)nc5ccccc5c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F23 mock treatment 0.251 9.37E-4 0.05 0.0504 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 F24 mock treatment 0.233 -0.0171 -0.92 -0.9169 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G01 compound treatment 0.236 -0.0141 -0.76 -0.7557 -1.0 3086066 TimTec1_005413 CCC(C)C(NCc1c(O)ccc2c(C)cc(=O)oc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G02 compound treatment 0.265 0.0149 0.8 0.8027 1.0 3212809 TimTec1_005414 COC(=O)n1c(SC)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G03 compound treatment 0.235 -0.0151 -0.81 -0.8094 -1.0 1428822 TimTec1_005415 CC(C)c1ccccc1NC(=O)CN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G04 compound treatment 0.276 0.0259 1.39 1.3938 1.0 1673731 TimTec1_005416 C=CCN(CC=C)C(=S)Oc1ccc(cc1)C(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G05 compound treatment 0.439 0.189 10.15 10.1531 1.0 3212810 TimTec1_005417 NNC(=O)c1cc(nn1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G06 compound treatment 0.258 0.00794 0.43 0.4265 1.0 3086070 TimTec1_005418 COC(=O)Nc1ccc(Br)cn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G07 compound treatment 0.234 -0.0161 -0.86 -0.8632 -1.0 3212811 TimTec1_005419 CN/1N(C(=NC(=O)\C1=C/c2ccc(O)cc2)C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G08 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1496851 TimTec1_005420 CCSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G09 compound treatment 0.509 0.259 13.91 13.9148 1.0 3212812 TimTec1_005421 CC1SC2=NNC(=CN2C1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G10 compound treatment 0.352 0.102 5.48 5.4779 1.0 1578108 TimTec1_005422 CC(=O)Oc1ccc(cc1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G11 compound treatment 0.544 0.294 15.8 15.7956 1.0 1637150 TimTec1_005423 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)Oc2cc3oc(=O)c4CCCCc4c3cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G12 compound treatment 0.274 0.0239 1.29 1.2864 1.0 1014256 TimTec1_005424 c1c([nH]c2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G13 compound treatment 0.296 0.0459 2.47 2.4686 1.0 1442327 TimTec1_005425 CCc1cc(C(=O)Cc2nc(C)cs2)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G14 compound treatment 0.477 0.227 12.2 12.1951 1.0 3212813 TimTec1_005426 CCOc1cc(/C=N/CCN2Cc3ccccc3C2=O)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G15 compound treatment 0.243 -0.00706 -0.38 -0.3795 -1.0 3086140 TimTec1_005427 COc1ccc(/C=N/S(=O)(=O)c2ccccc2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G16 compound treatment 0.294 0.0439 2.36 2.3611 1.0 3212814 TimTec1_005428 Clc1ccc(NC(=O)CSC(=O)c2ccccc2)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G17 compound treatment 0.31 0.0599 3.22 3.2209 1.0 3086142 TimTec1_005429 Oc1n[n+](no1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G18 compound treatment 0.46 0.21 11.28 11.2816 1.0 3212815 TimTec1_005430 COc1cc(/C=N/c2oc(C)c(C)c2C#N)cc(Br)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G19 compound treatment 0.347 0.0969 5.21 5.2092 1.0 1400147 TimTec1_005431 Cc1ccccc1OCC(=O)Nc2cc(Sc3ccccn3)cc(c2)S(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G20 compound treatment 0.42 0.17 9.13 9.1321 1.0 3086144 TimTec1_005432 C(=N/c1nnc2[nH]cnn12)\c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G21 compound treatment 0.364 0.114 6.12 6.1228 1.0 1704603 TimTec1_005433 CCN(CC)C(=O)N1CCc2ccccc2C1CN3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G22 compound treatment 0.26 0.00994 0.53 0.534 1.0 3212816 TimTec1_005434 CCc1c(C)[nH]c(=S)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G23 mock treatment 0.251 9.37E-4 0.05 0.0504 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 G24 mock treatment 0.238 -0.0121 -0.65 -0.6482 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H01 compound treatment 0.312 0.0619 3.33 3.3284 1.0 1451425 TimTec1_005435 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2nncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H02 compound treatment 0.356 0.106 5.69 5.6929 1.0 3086147 TimTec1_005436 COc1cc(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)cc(Br)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H03 compound treatment 0.473 0.223 11.98 11.9802 1.0 3212817 TimTec1_005437 Cc1cc-2c(cn1)/C(=N\c3ccccc3C)/c4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H04 compound treatment 0.406 0.156 8.38 8.3798 1.0 3086149 TimTec1_005438 Clc1ss/c(=N\c2ccccn2)/c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H05 compound treatment 0.491 0.241 12.95 12.9475 1.0 1471924 TimTec1_005439 COC(=O)c1ccc2c(c1)sc3nc(cn32)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H06 compound treatment 0.293 0.0429 2.31 2.3074 1.0 3212818 TimTec1_005440 Cc1ccc(/N=C/c2ccc3OCOc3c2)c(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H07 compound treatment 0.239 -0.0111 -0.59 -0.5945 -1.0 1713930 TimTec1_005441 CC(C)C(O)(C#CCN1CCCCC1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H08 compound treatment 0.501 0.251 13.48 13.4849 1.0 3212819 TimTec1_005442 CC(=O)NC1=NC(=O)/C(=C\c2ccc(Cl)cc2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H09 compound treatment 0.254 0.00394 0.21 0.2116 1.0 1216409 TimTec1_005443 Nc1nnc(SCC(=O)NCc2ccco2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H10 compound treatment 0.437 0.187 10.05 10.0456 1.0 3212820 TimTec1_005444 Cc1nc(Sc2ccccc2)c3oc4ccccc4c3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H11 compound treatment 0.244 -0.00606 -0.33 -0.3258 -1.0 1240888 TimTec1_005445 O=C1CSC2(CCCCC2)N1Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H12 compound treatment 0.42 0.17 9.13 9.1321 1.0 3212821 TimTec1_005446 Clc1ccc(NC(=O)CSC2=NCCS2)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H13 compound treatment 0.267 0.0169 0.91 0.9102 1.0 3212822 TimTec1_005447 COC(=O)C1=C(N)N(C2=C(C1c3ccccc3)C(=O)CCC2)c4cccc(c4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H14 compound treatment 0.292 0.0419 2.25 2.2536 1.0 1666111 TimTec1_005448 Oc1ccccc1N=c2c(=O)c3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H15 compound treatment 0.415 0.165 8.86 8.8634 1.0 3086218 TimTec1_005449 O=C(NC1CC1)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H16 compound treatment 0.254 0.00394 0.21 0.2116 1.0 1687122 TimTec1_005450 COc1ccc(cc1)C2CC3(OCCO3)C4(CCCCC4)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H17 compound treatment 0.6 0.35 18.8 18.8049 1.0 3212823 TimTec1_005451 Clc1cccc(/C=C\2/SC(=NC2=O)N3CCCC3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H18 compound treatment 0.47 0.22 11.82 11.819 1.0 1549014 TimTec1_005452 O=C(CSc1nnc2c3ccccc3[nH]c2n1)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H19 compound treatment 0.278 0.0279 1.5 1.5013 1.0 1530955 TimTec1_005453 COC(=O)C1=C(N)N(C2=C(C1c3ccccc3)C(=O)CC(C)(C)C2)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H20 compound treatment 0.334 0.0839 4.51 4.5106 1.0 1138726 TimTec1_005454 CCOC(=O)c1ccccc1NCn2c(=S)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H21 compound treatment 0.254 0.00394 0.21 0.2116 1.0 1258567 TimTec1_005455 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3cccc(c3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H22 compound treatment 0.368 0.118 6.34 6.3377 1.0 1345011 TimTec1_005456 OC(=O)c1ccccc1NC(=O)c2cc(ccc2Cl)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H23 mock treatment 0.238 -0.0121 -0.65 -0.6482 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 H24 mock treatment 0.245 -0.00506 -0.27 -0.272 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I01 compound treatment 0.276 0.0259 1.39 1.3938 1.0 1452955 TimTec1_005457 CCOC(=O)c1c(oc2ccc(OCC)cc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I02 compound treatment 0.295 0.0449 2.41 2.4148 1.0 1419694 TimTec1_005458 CCCc1ccc2c(N)c(sc2n1)C(=O)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I03 compound treatment 0.389 0.139 7.47 7.4662 1.0 1348330 TimTec1_005459 CCc1ccc(OC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I04 compound treatment 0.269 0.0189 1.02 1.0177 1.0 1011570 TimTec1_005460 COc1ccc2oc(=O)cc(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I05 compound treatment 0.306 0.0559 3.01 3.006 1.0 1591902 TimTec1_005461 NNC(=O)Cc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I06 compound treatment 0.434 0.184 9.88 9.8844 1.0 3086226 TimTec1_005462 CCCC(=O)n1c(=S)oc2cc(Cl)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I07 compound treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 3212824 TimTec1_005463 Cc1ccc(cc1)C(=O)/N=c\2/n(C)n(c(C)nc2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I08 compound treatment 0.249 -0.00106 -0.06 -0.0571 -1.0 1332287 TimTec1_005464 NC(=O)CN(c1ccc(Cl)cc1Cl)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I09 compound treatment 0.507 0.257 13.81 13.8073 1.0 1228160 TimTec1_005465 O=C(SCc1nc2ccccc2[nH]1)c3ccc(cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I10 compound treatment 0.276 0.0259 1.39 1.3938 1.0 3212825 TimTec1_005466 Cc1ccc2cc3/C(=N\C4CCCCC4)/c5ccccc5-c3nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I11 compound treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 3086229 TimTec1_005467 Cc1ccc2nc(NCc3ccccc3)c(/C=N/c4ccc(Cl)cc4)c(=O)n2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I12 compound treatment 0.424 0.174 9.35 9.347 1.0 3212826 TimTec1_005468 COc1ccc(/N=C\2/c3ccccc3-c4nc5ccccc5nc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I13 compound treatment 0.275 0.0249 1.34 1.3401 1.0 1582817 TimTec1_005469 CN(C)Cc1c(C)cc2oc(=O)c3CCCCc3c2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I14 compound treatment 0.257 0.00694 0.37 0.3728 1.0 3086232 TimTec1_005470 CCc1ccc(cc1)c2nn(c3ccccc3)c(=S)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I15 compound treatment 0.254 0.00394 0.21 0.2116 1.0 3212903 TimTec1_005471 CN(C)c1ccc(/C=N/S(=O)(=O)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I16 compound treatment 0.277 0.0269 1.45 1.4476 1.0 1444311 TimTec1_005472 COC(=O)c1ccc(OC(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I17 compound treatment 0.312 0.0619 3.33 3.3284 1.0 3212904 TimTec1_005473 CSc1c(CC(=O)Nc2ccccc2)n(Cc3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I18 compound treatment 0.477 0.227 12.2 12.1951 1.0 3086235 TimTec1_005474 Fc1ccc(/C=N/c2nnc3[nH]cnn23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I19 compound treatment 0.367 0.117 6.28 6.284 1.0 3212905 TimTec1_005475 CC(C)(C)c1ccc(cc1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I20 compound treatment 0.256 0.00594 0.32 0.3191 1.0 3086300 TimTec1_005476 CCC1(C)OC(=O)N(C1=C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I21 compound treatment 0.269 0.0189 1.02 1.0177 1.0 3086302 TimTec1_005477 COCc1cc(C)nc2snc(Br)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I22 compound treatment 0.273 0.0229 1.23 1.2326 1.0 3212906 TimTec1_005478 Cc1cc(C)c2c(N)c(sc2n1)C(=O)OC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I23 mock treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 I24 mock treatment 0.252 0.00194 0.1 0.1041 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J01 compound treatment 0.265 0.0149 0.8 0.8027 1.0 1654696 TimTec1_005479 CC(C)C1N(CCN1S(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J02 compound treatment 0.26 0.00994 0.53 0.534 1.0 3086304 TimTec1_005480 FC(F)(F)COc1nc(nc(n1)N2CCN(CC2)c3ccccc3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J03 compound treatment 0.282 0.0319 1.72 1.7163 1.0 1724083 TimTec1_005481 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J04 compound treatment 0.543 0.293 15.74 15.7418 1.0 3086306 TimTec1_005482 CCCCc1c(C)c2ccc(OCC=C)cc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J05 compound treatment 0.582 0.332 17.84 17.8376 1.0 3212907 TimTec1_005483 COC(=O)CSC1=NC(=O)/C(=C/c2ccc(OC)cc2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J06 compound treatment 0.312 0.0619 3.33 3.3284 1.0 3086308 TimTec1_005484 Brc1cc2OCOc2cc1/C=N/c3c(nc4ccccn34)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J07 compound treatment 0.443 0.193 10.37 10.3681 1.0 3212908 TimTec1_005485 Clc1ccc(Oc2ccc(/N=C/c3ccc(I)o3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J08 compound treatment 0.49 0.24 12.89 12.8937 1.0 3212909 TimTec1_005486 CC(=O)NC1=NC(=O)/C(=C\c2ccc(C)cc2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J09 compound treatment 0.266 0.0159 0.86 0.8564 1.0 3086311 TimTec1_005487 CCn1c2ccccc2c3cc(/C=N/c4ccc(Cl)cc4)ccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J10 compound treatment 0.361 0.111 5.96 5.9615 1.0 1618704 TimTec1_005488 Cc1cc(=O)oc2c(C)c(O)c(CC=C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J11 compound treatment 0.244 -0.00606 -0.33 -0.3258 -1.0 1654232 TimTec1_005489 CN(CP(=O)(O)CN1CCOCC1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J12 compound treatment 0.248 -0.00206 -0.11 -0.1108 -1.0 3212910 TimTec1_005490 Clc1ccc(cc1)N2C(=C)C3(CCCCC3)OC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J13 compound treatment 0.49 0.24 12.89 12.8937 1.0 3212911 TimTec1_005491 OCCn/1c(cs\c1=N/c2ccccc2)c3cccc(c3)N4C(=O)c5ccccc5C4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J14 compound treatment 0.572 0.322 17.3 17.3002 1.0 3086315 TimTec1_005492 OCCn/1c(cs\c1=N/c2cccc(c2)C(F)(F)F)c3ccc(cc3)S(=O)(=O)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J15 compound treatment 0.393 0.143 7.68 7.6812 1.0 1655602 TimTec1_005493 CCOC(=O)C(Cc1ccc(NC(=O)c2ccccc2)cc1)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J16 compound treatment 0.26 0.00994 0.53 0.534 1.0 1386199 TimTec1_005494 CC1(C)OC(=O)N(CCCC(=O)O)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J17 compound treatment 0.33 0.0799 4.3 4.2957 1.0 1068676 TimTec1_005495 Cc1ccc(cc1)S(=O)(=O)C=C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J18 compound treatment 0.303 0.0529 2.84 2.8448 1.0 3086318 TimTec1_005496 CCOC(=O)C1=C(NC(=S)NC1c2cccc(OC)c2O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J19 compound treatment 0.399 0.149 8.0 8.0036 1.0 1433302 TimTec1_005497 COc1cccc(c1)c2nn(CN3CCCC3)c(=S)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J20 compound treatment 0.362 0.112 6.02 6.0153 1.0 3212912 TimTec1_005498 COc1ccc(CN(C2CC(=O)N(C2=O)c3ccccc3)C(=O)/C=C/C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J21 compound treatment 0.368 0.118 6.34 6.3377 1.0 3086320 TimTec1_005499 CCOC(=O)c1c(/N=C/c2c(O)ccc3ccccc23)sc4CCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J22 compound treatment 0.438 0.188 10.1 10.0994 1.0 3212913 TimTec1_005500 CCOc1cc(/C=c/2\sc3nc4c(C)c(C)ccc4n3c2=O)cc(Cl)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J23 mock treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 J24 mock treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K01 compound treatment 0.289 0.0389 2.09 2.0924 1.0 1526103 TimTec1_005501 CC(=O)Oc1ccc2oc(c(C(=O)O)c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K02 compound treatment 0.274 0.0239 1.29 1.2864 1.0 1186869 TimTec1_005502 COc1ccccc1C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K03 compound treatment 0.463 0.213 11.44 11.4428 1.0 3212914 TimTec1_005503 O=C(NC(=S)NC1CCCC1)/C=C/c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K04 compound treatment 0.223 -0.0271 -1.45 -1.4543 -1.0 3086394 TimTec1_005504 Cc1ccc(cc1)S(=O)(=O)N=C2NCN(CN2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K05 compound treatment 0.251 9.37E-4 0.05 0.0504 1.0 1131736 TimTec1_005505 COc1ccc(cc1OC)c2c(C)nn(c2NC(=O)C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K06 compound treatment 0.283 0.0329 1.77 1.77 1.0 1007406 TimTec1_005506 COc1ccc(OC(=O)c2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K07 compound treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 3212915 TimTec1_005507 Clc1ccccc1C(=O)N=C2NCCCCCN2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K08 compound treatment 0.265 0.0149 0.8 0.8027 1.0 1323784 TimTec1_005508 Cc1cccc(c1)S(=O)(=O)N2CCSC2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K09 compound treatment 0.238 -0.0121 -0.65 -0.6482 -1.0 1116167 TimTec1_005509 Cn1c(=O)n(C)c2nc(Br)n(CC(=O)c3ccccc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K10 compound treatment 0.25 -6.25E-5 0.0 -0.0034 -1.0 1464973 TimTec1_005510 OC(=O)c1cc(c2ccccc2)c(cn1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K11 compound treatment 0.448 0.198 10.64 10.6367 1.0 3212916 TimTec1_005511 Cc1ccc2nc(Nc3ccc(Cl)cc3)c(/C=N/O)c(=O)n2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K12 compound treatment 0.457 0.207 11.12 11.1204 1.0 3086399 TimTec1_005512 Cc1cccc2nc3/C(=N\c4ccccc4)/c5ccccc5-c3nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K13 compound treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 1486848 TimTec1_005513 CCCc1cc2c(=O)c(coc2cc1O)c3nc4ccccc4n3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K14 compound treatment 0.357 0.107 5.75 5.7466 1.0 3086401 TimTec1_005514 CSc1cccc2c(SC)cccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K15 compound treatment 0.303 0.0529 2.84 2.8448 1.0 3212917 TimTec1_005515 C(N1CCN(CC1)/N=C/c2ccncc2)c3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K16 compound treatment 0.326 0.0759 4.08 4.0807 1.0 3086404 TimTec1_005516 O=c1/c(=C/C=C/c2ccccc2)/sc3nc4ccccc4n13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K17 compound treatment 0.287 0.0369 1.98 1.9849 1.0 1919931 TimTec1_005517 Sc1nnc(o1)C2(CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K18 compound treatment 0.278 0.0279 1.5 1.5013 1.0 3212918 TimTec1_005518 Cc1ccc(cc1)C2=C/C(=C/c3c(O)ccc4ccccc34)/C(=O)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K19 compound treatment 0.508 0.258 13.86 13.861 1.0 3086406 TimTec1_005519 COc1ccc(cc1)N2C(=O)CC(S/C(=N/c3ccccc3)/N)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K20 compound treatment 0.464 0.214 11.5 11.4966 1.0 3212919 TimTec1_005520 COc1ccc(OCCNS(=O)(=O)c2ccc3c(c2)oc4ccccc43)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K21 compound treatment 0.286 0.0359 1.93 1.9312 1.0 3086408 TimTec1_005521 Cc1ccccc1C2C(=C(N)SC(=C2C#N)N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K22 compound treatment 0.395 0.145 7.79 7.7886 1.0 3212920 TimTec1_005522 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3F)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K23 mock treatment 0.262 0.0119 0.64 0.6415 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 K24 mock treatment 0.258 0.00794 0.43 0.4265 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L01 compound treatment 0.293 0.0429 2.31 2.3074 1.0 3212921 TimTec1_005523 Oc1ccc(Br)cc1/C=N/c2ccc3nc(SCC(=O)Nc4ccccc4)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L02 compound treatment 0.27 0.0199 1.07 1.0714 1.0 3086411 TimTec1_005524 Fc1cccc(c1)N2C(=O)/C(=C/C=C/c3ccccc3)/SC2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L03 compound treatment 0.449 0.199 10.69 10.6905 1.0 3086413 TimTec1_005525 NC1=C(C#N)C(c2ccsc2)c3ccc4ccccc4c3O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L04 compound treatment 0.519 0.269 14.45 14.4521 1.0 1682053 TimTec1_005526 Cc1ccc2nc(cn2c1)c3ccc(O)c(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L05 compound treatment 0.28 0.0299 1.61 1.6088 1.0 1536268 TimTec1_005527 Cc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccccc4)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L06 compound treatment 0.391 0.141 7.57 7.5737 1.0 3211217 TimTec1_005528 CC1(C)NN1CCCN2NC2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L07 compound treatment 0.288 0.0379 2.04 2.0387 1.0 1273515 TimTec1_005529 OC(=O)c1cc(Cl)c(Cl)cc1C(=O)Nc2ccc(Oc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L08 compound treatment 0.25 -6.25E-5 0.0 -0.0034 -1.0 1548568 TimTec1_005530 C=CCNC(=O)C1CC1(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L09 compound treatment 0.444 0.194 10.42 10.4218 1.0 3211218 TimTec1_005531 Cc1ccc2nc(sc2c1)c3ccc(/N=C\c4ccc[nH]4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L10 compound treatment 0.258 0.00794 0.43 0.4265 1.0 1209920 TimTec1_005532 OCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L11 compound treatment 0.605 0.355 19.07 19.0736 1.0 1148781 TimTec1_005533 CCN(CC)C(=O)c1ccc(o1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L12 compound treatment 0.358 0.108 5.8 5.8003 1.0 3211219 TimTec1_005534 CCc1c(C)[nH]c(C(=O)OCc2ccccc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L13 compound treatment 0.235 -0.0151 -0.81 -0.8094 -1.0 1175161 TimTec1_005535 O=P(CCN1CCOCC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L14 compound treatment 0.245 -0.00506 -0.27 -0.272 -1.0 3086492 TimTec1_005536 OC(=O)c1ccc(/N=C/c2ccc(OC(=O)c3sc4ccccc4c3Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L15 compound treatment 0.268 0.0179 0.96 0.9639 1.0 3211220 TimTec1_005537 CCOC(=O)CC1=C(C#N)C(C(=C(N)O1)C(=O)OCC)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L16 compound treatment 0.407 0.157 8.43 8.4335 1.0 1174009 TimTec1_005538 CCCSc1nnc2c3ccccc3n(Cc4ccccc4)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L17 compound treatment 0.328 0.0779 4.19 4.1882 1.0 3211221 TimTec1_005539 COc1cc(/C=C/2\S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc(OC)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L18 compound treatment 0.285 0.0349 1.88 1.8775 1.0 3211222 TimTec1_005540 CC(=O)N1c2ccccc2C3=NNC(=S)NC13O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L19 compound treatment 0.248 -0.00206 -0.11 -0.1108 -1.0 3086496 TimTec1_005541 COc1cc(/C=N/c2ccc(\N=C\c3ccc(OC(=O)C)c(OC)c3)cc2)ccc1OC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L20 compound treatment 0.333 0.0829 4.46 4.4569 1.0 3211223 TimTec1_005542 O=C/1N(C2CCCC2)/C(=N\c3ccccc3)/S\C1=C\c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L21 compound treatment 0.426 0.176 9.45 9.4545 1.0 1270230 TimTec1_005543 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)cc3)C(=O)CCC2)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L22 compound treatment 0.318 0.0679 3.65 3.6508 1.0 3086498 TimTec1_005544 CC(C)/C=N/N1C(C(C)C)C(C#N)(C#N)C(=C1N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L23 mock treatment 0.241 -0.00906 -0.49 -0.487 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 L24 mock treatment 0.25 -6.25E-5 0.0 -0.0034 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M01 compound treatment 0.328 0.0779 4.19 4.1882 1.0 1414805 TimTec1_005545 CC(NC(=O)OCc1ccccc1)C(=O)Oc2cc3oc(=O)c(Cl)c(C)c3cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M02 compound treatment 0.304 0.0539 2.9 2.8985 1.0 3086501 TimTec1_005546 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M03 compound treatment 0.251 9.37E-4 0.05 0.0504 1.0 1514197 TimTec1_005547 Cc1cccc(NCN2C(=O)CSC2=O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M04 compound treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 1084346 TimTec1_005548 CCOC(=O)Cc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M05 compound treatment 0.497 0.247 13.27 13.2699 1.0 1367503 TimTec1_005549 CC(C)C(NS(=O)(=O)c1ccc(C)cc1)C(=O)Oc2ccc3c4CCCCc4c(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M06 compound treatment 0.271 0.0209 1.13 1.1251 1.0 1003422 TimTec1_005550 CC(=O)Oc1ccc(cc1)C(=O)c2ccc(OC(=O)C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M07 compound treatment 0.453 0.203 10.91 10.9054 1.0 3085493 TimTec1_005551 CC1=C(N(N/C(=N\CC=C)/S1)c2ccc3OCCOc3c2)C(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M08 compound treatment 0.262 0.0119 0.64 0.6415 1.0 1442839 TimTec1_005552 OCCN1CCN(CC1)C(=O)Nc2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M09 compound treatment 0.255 0.00494 0.27 0.2653 1.0 1468923 TimTec1_005553 CCOC(=O)c1c(N)cc2[nH]c(=S)[nH]c(=O)c2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M10 compound treatment 0.262 0.0119 0.64 0.6415 1.0 3085496 TimTec1_005554 Cc1ccccc1c2nccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M11 compound treatment 0.238 -0.0121 -0.65 -0.6482 -1.0 1298715 TimTec1_005555 CCOC(=O)NS(=O)(=O)c1ccc(C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M12 compound treatment 0.314 0.0639 3.44 3.4359 1.0 3211224 TimTec1_005556 Cc1ccc-2c(c1)/C(=C/c3ccncc3)/c4cc5ccccc5nc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M13 compound treatment 0.469 0.219 11.77 11.7652 1.0 1313295 TimTec1_005557 Cc1c(OCC(=O)OCc2ccccc2)ccc3c4ccccc4c(=O)oc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M14 compound treatment 0.249 -0.00106 -0.06 -0.0571 -1.0 1489666 TimTec1_005558 COC(=O)C(C)N(C(=O)c1c(F)cccc1F)c2c(C)cccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M15 compound treatment 0.269 0.0189 1.02 1.0177 1.0 1632514 TimTec1_005559 Clc1ccccc1N2C(=O)CC(Nc3ccccc3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M16 compound treatment 0.553 0.303 16.28 16.2792 1.0 3085499 TimTec1_005560 CCOC(=O)CSC1=NC(=O)/C(=C\c2ccc(Cl)cc2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M17 compound treatment 0.257 0.00694 0.37 0.3728 1.0 3211225 TimTec1_005561 CC1(C)OC(=O)N(Cc2ccccc2)C1=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M18 compound treatment 0.401 0.151 8.11 8.1111 1.0 1242728 TimTec1_005562 Cc1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M19 compound treatment 0.364 0.114 6.12 6.1228 1.0 1175444 TimTec1_005563 CCOc1ccc2nc(SCc3c[nH]c4ccccc34)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M20 compound treatment 0.255 0.00494 0.27 0.2653 1.0 1133231 TimTec1_005564 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M21 compound treatment 0.536 0.286 15.37 15.3657 1.0 3085503 TimTec1_005565 COc1cc(/C=N/c2c(nc3ccccn23)c4ccc(O)c(OC)c4)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M22 compound treatment 0.367 0.117 6.28 6.284 1.0 3211226 TimTec1_005566 CC(=O)N1CC=C2[C@H](C1)[C@@H](c3ccc(F)cc3F)C(C#N)(C#N)C(=C2C#N)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M23 mock treatment 0.253 0.00294 0.16 0.1579 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 M24 mock treatment 0.262 0.0119 0.64 0.6415 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N01 compound treatment 0.283 0.0329 1.77 1.77 1.0 2116249 TimTec1_005567 O=C/1NC(=S)N(C(=O)\C1=C\c2c[nH]c3ccccc23)c4cccc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N02 compound treatment 0.26 0.00994 0.53 0.534 1.0 1630568 TimTec1_005568 CC(=Cc1c(O)nc2ccccn2c1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N03 compound treatment 0.322 0.0719 3.87 3.8658 1.0 1455275 TimTec1_005569 CCOC(=O)CCC1(CCC(=O)OCC)c2ccccc2-c3nc4ccccc4cc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N04 compound treatment 0.283 0.0329 1.77 1.77 1.0 1423540 TimTec1_005570 CCNC(=O)C1CN(C(=O)C1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N05 compound treatment 0.282 0.0319 1.72 1.7163 1.0 3211227 TimTec1_005571 S/C(=C(/C(=O)c1ccccc1)\[n+]2ccccc2)/Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N06 compound treatment 0.286 0.0359 1.93 1.9312 1.0 3085508 TimTec1_005572 CCOC(=O)Cn/1c(cs\c1=N/c2ccc(F)cc2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N07 compound treatment 0.255 0.00494 0.27 0.2653 1.0 3211228 TimTec1_005573 S=c1[nH]nc([nH]1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N08 compound treatment 0.265 0.0149 0.8 0.8027 1.0 1670836 TimTec1_005574 COc1ccc2C(=O)C(CCc2c1C)C3(O)C(=O)N(C)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N09 compound treatment 0.335 0.0849 4.56 4.5644 1.0 2116264 TimTec1_005575 Cc1[nH]c2ccccc2c1/C=N/c3ccc(\N=C\c4c(C)[nH]c5ccccc45)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N10 compound treatment 0.239 -0.0111 -0.59 -0.5945 -1.0 1703166 TimTec1_005576 Cn1c(SCC(=O)N2CCCCC2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N11 compound treatment 0.255 0.00494 0.27 0.2653 1.0 3211229 TimTec1_005577 COc1ccc(cc1)n2nc(C#N)c(N)c(C#N)c2=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N12 compound treatment 0.277 0.0269 1.45 1.4476 1.0 3085531 TimTec1_005578 O=C(Cn1nnc2ccccc12)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N13 compound treatment 0.389 0.139 7.47 7.4662 1.0 1157884 TimTec1_005579 Cc1ccc(cc1C)c2csc(Nc3ccc4OCOc4c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N14 compound treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 1380401 TimTec1_005580 CCOc1ccc(cc1)N2C(=O)CC(N(Cc3ccc(Cl)cc3)C(=O)c4ccc(Cl)cc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N15 compound treatment 0.265 0.0149 0.8 0.8027 1.0 3085535 TimTec1_005581 OC(=O)CN1C(=O)/C(=C\c2ccsc2)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N16 compound treatment 0.486 0.236 12.68 12.6788 1.0 3211425 TimTec1_005582 Oc1ccccc1/C=N/c2ccc3nc(SCC(=O)NCCOc4ccccc4)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N17 compound treatment 0.253 0.00294 0.16 0.1579 1.0 1583377 TimTec1_005583 CC1CN(CN2C(=O)c3ccccc3C2=O)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N18 compound treatment 0.241 -0.00906 -0.49 -0.487 -1.0 1137144 TimTec1_005584 Nc1nnc(CCN2CCCCC2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N19 compound treatment 0.281 0.0309 1.66 1.6625 1.0 3211426 TimTec1_005585 CC1=C(C(NC(=O)N1)c2ccc3OCOc3c2)C(=O)OCC(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N20 compound treatment 0.293 0.0429 2.31 2.3074 1.0 3211427 TimTec1_005586 COc1cc(/C=C\2/S/C(=N/Cc3ccccc3)/N(Cc4ccccc4)C2=O)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N21 compound treatment 0.441 0.191 10.26 10.2606 1.0 3085538 TimTec1_005587 Cc1ccc(/C=N/c2ccc(Nc3ccccc3)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N22 compound treatment 0.494 0.244 13.11 13.1087 1.0 1176605 TimTec1_005588 Fc1ccc(cc1)c2nc3c([nH]2)c4ccccc4c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N23 mock treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 N24 mock treatment 0.249 -0.00106 -0.06 -0.0571 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O01 compound treatment 0.403 0.153 8.22 8.2185 1.0 1527225 TimTec1_005589 CCc1cc2c(=O)c(c3nc4ccccc4[nH]3)c(C)oc2cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O02 compound treatment 0.273 0.0229 1.23 1.2326 1.0 3085541 TimTec1_005590 NC1=C(C#N)C2=CCSC[C@H]2[C@H](c3cccc(Cl)c3)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O03 compound treatment 0.312 0.0619 3.33 3.3284 1.0 1190084 TimTec1_005591 CCOc1ccccc1C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O04 compound treatment 0.268 0.0179 0.96 0.9639 1.0 1047189 TimTec1_005592 Clc1ccc(cc1)S(=O)(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O05 compound treatment 0.477 0.227 12.2 12.1951 1.0 3211428 TimTec1_005593 CC(C)(C)OC(=O)C1CCC(CN1)C(=O)Oc2ccc3c4CCCCc4c(=O)oc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O06 compound treatment 0.22 -0.0301 -1.62 -1.6155 -1.0 1652072 TimTec1_005594 COC(=O)C1C(C(C(=O)OC)C(C)(O)CC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O07 compound treatment 0.262 0.0119 0.64 0.6415 1.0 3211429 TimTec1_005595 Clc1cccc(NC(=O)N=C2NCCCCCN2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O08 compound treatment 0.221 -0.0291 -1.56 -1.5618 -1.0 1649723 TimTec1_005596 CC(C)CN1C(=O)N(C(n2oc(=O)n(c3ccccc3)c2=O)C1(C)C)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O09 compound treatment 0.446 0.196 10.53 10.5293 1.0 1511407 TimTec1_005597 CCc1c(C)c(C#N)c2nc3ccccc3n2c1NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O10 compound treatment 0.231 -0.0191 -1.02 -1.0244 -1.0 3085546 TimTec1_005598 Cc1ccccc1c2ccc3cccc(C)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O11 compound treatment 0.246 -0.00406 -0.22 -0.2183 -1.0 3211430 TimTec1_005599 S(c1nnc[nH]1)c2nc3ccccc3nc2Sc4nnc[nH]4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O12 compound treatment 0.256 0.00594 0.32 0.3191 1.0 1067246 TimTec1_005600 COc1ccc(C)c2C(=O)CCCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O13 compound treatment 0.271 0.0209 1.13 1.1251 1.0 1520144 TimTec1_005601 CC(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O14 compound treatment 0.251 9.37E-4 0.05 0.0504 1.0 1641803 TimTec1_005602 Clc1cc(OC(=O)C2CCCCC2)ccc1OC(=O)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O15 compound treatment 0.337 0.0869 4.67 4.6718 1.0 3211431 TimTec1_005603 OC1=C(C#N)[C@@H]([C@H](C(=O)N1CCc2ccccc2)[n+]3ccccc3)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O16 compound treatment 0.358 0.108 5.8 5.8003 1.0 1578376 TimTec1_005604 Cc1cc(=O)oc2cc(OC(=O)c3cc4ccccc4o3)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O17 compound treatment 0.283 0.0329 1.77 1.77 1.0 3211432 TimTec1_005605 CCc1nc(SC/C=C/c2ccccc2)c(C#N)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O18 compound treatment 0.513 0.263 14.13 14.1297 1.0 1218415 TimTec1_005606 CCOC(=O)C1=C(C)NC(=S)NC1c2ccc(OCC(=O)N3CCCCC3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O19 compound treatment 0.259 0.00894 0.48 0.4803 1.0 1784221 TimTec1_005607 CCc1oc2ccccc2c1C(=O)CCN3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O20 compound treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 3085555 TimTec1_005608 Cc1c(Cl)cccc1NC2=NS(=O)(=O)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O21 compound treatment 0.25 -6.25E-5 0.0 -0.0034 -1.0 1638741 TimTec1_005609 CC(C)NC(=O)C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O22 compound treatment 0.51 0.26 13.97 13.9685 1.0 3211433 TimTec1_005610 COc1ccc(cc1)C(=O)CSc2nsc(SCC(=O)c3ccc(OC)cc3)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O23 mock treatment 0.254 0.00394 0.21 0.2116 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 O24 mock treatment 0.265 0.0149 0.8 0.8027 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P01 compound treatment 0.31 0.0599 3.22 3.2209 1.0 3085557 TimTec1_005611 Oc1ccc(Br)cc1/C=N/CC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P02 compound treatment 0.306 0.0559 3.01 3.006 1.0 1175377 TimTec1_005612 Sc1nnc2c3ccccc3n(Cc4ccccc4)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P03 compound treatment 0.288 0.0379 2.04 2.0387 1.0 3211434 TimTec1_005613 Cc1ccccc1c2nnc3-c4ccccc4CC(C)(C)n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P04 compound treatment 0.232 -0.0181 -0.97 -0.9706 -1.0 1673398 TimTec1_005614 CCCC1C(C2c3ccccc3C1c4ccccc24)C(=O)Nc5ccccc5OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P05 compound treatment 0.326 0.0759 4.08 4.0807 1.0 1642050 TimTec1_005615 N#Cc1ccc(cc1C#N)n2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P06 compound treatment 0.248 -0.00206 -0.11 -0.1108 -1.0 1492547 TimTec1_005616 CC1(C)CC(=O)c2cc(c3ccc(Br)cc3)n(CC(=O)O)c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P07 compound treatment 0.232 -0.0181 -0.97 -0.9706 -1.0 3085561 TimTec1_005617 Oc1ccc(/C=N/c2ccc3[nH]c(=O)[nH]c3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P08 compound treatment 0.346 0.0959 5.16 5.1555 1.0 3211435 TimTec1_005618 CCOc1ccc2ccccc2c1/C=C/3\C(=O)NC(=S)N(C3=O)c4cccc(Cl)c4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P09 compound treatment 0.351 0.101 5.42 5.4242 1.0 3085562 TimTec1_005619 COc1cccc(c1)c2nnc(SCC(=O)NCCOc3ccccc3)n2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P10 compound treatment 0.263 0.0129 0.7 0.6952 1.0 3211436 TimTec1_005620 Cn1cnnc1SCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P11 compound treatment 0.242 -0.00806 -0.43 -0.4333 -1.0 1443624 TimTec1_005621 CCOP(=O)(C)C1(CC1)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P12 compound treatment 0.261 0.0109 0.59 0.5878 1.0 1354424 TimTec1_005622 CCN(CC)C(=O)C1(CC1)P(=O)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P13 compound treatment 0.406 0.156 8.38 8.3798 1.0 1466364 TimTec1_005623 COCc1cc(C)c2c(n1)sc3c4nc5ccccc5n4c(C)nc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P14 compound treatment 0.522 0.272 14.61 14.6134 1.0 3211437 TimTec1_005624 C=CCN/1C(=O)/C(=C\c2cccs2)/S\C1=N\c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P15 compound treatment 0.326 0.0759 4.08 4.0807 1.0 1444037 TimTec1_005625 Nc1nc(CCc2ccccc2)c(C#N)c(N)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P16 compound treatment 0.498 0.248 13.32 13.3236 1.0 3085567 TimTec1_005626 COc1ccc2NC(=O)/C(=C/3\SC(=S)NC3=O)/c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P17 compound treatment 0.561 0.311 16.71 16.7091 1.0 1603829 TimTec1_005627 Nc1nc(CSc2nc3ccccc3s2)nc(Nc4ccccc4)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P18 compound treatment 0.305 0.0549 2.95 2.9522 1.0 1171831 TimTec1_005628 Cc1ccc(Nc2nc(C)nc3c4ccccc4oc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P19 compound treatment 0.354 0.104 5.59 5.5854 1.0 1524350 TimTec1_005629 COC(=O)c1ccc(NC(=O)Cn2nc(SC)n(N)c2=S)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P20 compound treatment 0.279 0.0289 1.56 1.555 1.0 3211438 TimTec1_005630 CCOC(=O)/C=C/c1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P21 compound treatment 0.267 0.0169 0.91 0.9102 1.0 3211439 TimTec1_005631 CCOC(=O)C1C2NC(=S)N[C@]1(C)Oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P22 compound treatment 0.287 0.0369 1.98 1.9849 1.0 3085589 TimTec1_005632 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)ccc1OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P23 mock treatment 0.247 -0.00306 -0.16 -0.1646 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2078 P24 mock treatment 0.253 0.00294 0.16 0.1579 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A01 compound treatment 0.25 -0.00447 -0.24 -0.2401 -1.0 3211440 TimTec1_005633 CC(=O)n1cc(/C=c\2/sc3nc4c(C)c(C)ccc4n3c2=O)c(n1)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A02 compound treatment 0.476 0.222 11.9 11.9046 1.0 3085592 TimTec1_005634 Cc1nc(N)sc1c2csc(Nc3cccc(Cl)c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A03 compound treatment 0.264 0.00953 0.51 0.5122 1.0 3211529 TimTec1_005635 CCC(=O)N1N=C(CC1(O)c2ccc(F)cc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A04 compound treatment 0.244 -0.0105 -0.56 -0.5626 -1.0 1419705 TimTec1_005636 CC1CCC(=C(C#N)C(=O)NCc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A05 compound treatment 0.246 -0.00847 -0.46 -0.4551 -1.0 1732858 TimTec1_005637 Fc1ccc2C(=O)N(C3CCCCCCC3)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A06 compound treatment 0.27 0.0155 0.83 0.8346 1.0 3211530 TimTec1_005638 Fc1ccc(cc1)C2Nc3ccc(OC(F)(F)F)cc3C4C=CCC42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A07 compound treatment 0.242 -0.0125 -0.67 -0.67 -1.0 1737054 TimTec1_005639 Nn1c(CO)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A08 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1175030 TimTec1_005640 CC(C)(O)c1cn2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A09 compound treatment 0.247 -0.00747 -0.4 -0.4014 -1.0 1364286 TimTec1_005641 COc1ccc(cc1)C(CC#N)C2CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A10 compound treatment 0.521 0.267 14.32 14.3228 1.0 1357576 TimTec1_005642 O=C(NCCc1ccc(cc1)S(=O)(=O)N2CCCC2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A11 compound treatment 0.325 0.0705 3.79 3.7902 1.0 3211531 TimTec1_005643 CNC(=S)N(C)/N=C\1/C(=O)N(Cc2c(Cl)cccc2Cl)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A12 compound treatment 0.314 0.0595 3.2 3.1991 1.0 3085598 TimTec1_005644 CCc1nn2c(C)cc(O)nc2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A13 compound treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 1530862 TimTec1_005645 C1Cc2c(C1)c3c(ccc4ccccc43)nc2c5cccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A14 compound treatment 0.34 0.0855 4.6 4.5963 1.0 1575017 TimTec1_005646 CC1CN(OC(O1)c2ccc3OCOc3c2)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A15 compound treatment 0.255 5.31E-4 0.03 0.0285 1.0 3085600 TimTec1_005647 OC(=O)C1CC(=O)N(Cc2ccccc2)/C(=N/c3ccc(F)cc3)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A16 compound treatment 0.26 0.00553 0.3 0.2972 1.0 1628881 TimTec1_005648 CCC(N)C1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A17 compound treatment 0.297 0.0425 2.29 2.2855 1.0 3085602 TimTec1_005649 FC(F)(F)c1cccc(NCn2c(=S)oc3ccc(Cl)cc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A18 compound treatment 0.384 0.13 6.96 6.9607 1.0 1127153 TimTec1_005650 CC(C)c1ccccc1NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A19 compound treatment 0.269 0.0145 0.78 0.7809 1.0 1348096 TimTec1_005651 CN(C)c1nc2n(C)c(=O)n(C)c(=O)c2n1CC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A20 compound treatment 0.269 0.0145 0.78 0.7809 1.0 1611764 TimTec1_005652 COC(=O)CCn1cc(F)c(N)nc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A21 compound treatment 0.272 0.0175 0.94 0.9421 1.0 1564099 TimTec1_005653 CN(C)N=Nc1ccc(cc1)S(=O)(=O)NC(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A22 compound treatment 0.459 0.205 10.99 10.9911 1.0 1394944 TimTec1_005654 C=CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A23 mock treatment 0.255 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 A24 mock treatment 0.255 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B01 compound treatment 0.497 0.243 13.03 13.0331 1.0 3211532 TimTec1_005655 SC1=NC(=O)/C(=C\c2cccnc2)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B02 compound treatment 0.283 0.0285 1.53 1.5332 1.0 1491875 TimTec1_005656 COc1ccc(cc1)S(=O)(=O)NCCC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B03 compound treatment 0.273 0.0185 1.0 0.9958 1.0 3085609 TimTec1_005657 Cc1nn(c(O)c1CCC#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B04 compound treatment 0.218 -0.0365 -1.96 -1.9598 -1.0 3211533 TimTec1_005658 FC(F)(F)C(NCC1(CC2CC3CC(C2)C1)C3)(NC(=O)c4ccccc4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B05 compound treatment 0.257 0.00253 0.14 0.136 1.0 3085612 TimTec1_005659 COc1cc(NC=C2C(=O)NC(=O)NC2=O)cc(OC)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B06 compound treatment 0.241 -0.0135 -0.72 -0.7238 -1.0 3085613 TimTec1_005660 Cc1cc(cc(C)c1O)C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B07 compound treatment 0.338 0.0835 4.49 4.4888 1.0 3211534 TimTec1_005661 FC(F)(F)c1ccccc1C2C3=C(CCCC3=O)Nc4ccc5ncccc5c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B08 compound treatment 0.257 0.00253 0.14 0.136 1.0 1339353 TimTec1_005662 CCc1ccc(cc1)C(=O)c2c(c(c3cc(ccn23)C(C)(C)C)S(=O)(=O)CC)S(=O)(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B09 compound treatment 0.254 -4.69E-4 -0.03 -0.0252 -1.0 1735427 TimTec1_005663 CC1(C)CC(=O)CC(C)(C)N1OC(=O)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B10 compound treatment 0.286 0.0315 1.69 1.6944 1.0 1503527 TimTec1_005664 CCC(NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B11 compound treatment 0.311 0.0565 3.04 3.0379 1.0 1555325 TimTec1_005665 CCOc1ccccc1NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B12 compound treatment 0.261 0.00653 0.35 0.351 1.0 3085617 TimTec1_005666 COc1ccc(/C=N/n2c(=O)c(nn3cnnc23)C(C)(C)C)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B13 compound treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 1402991 TimTec1_005667 Cc1ccc(Oc2cc(C#N)c(C#N)cc2n3nnc4ccccc34)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B14 compound treatment 0.491 0.237 12.71 12.7107 1.0 3085619 TimTec1_005668 CC/N=C\1/S/C(=C/c2sccc2C)/C(=O)N1CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B15 compound treatment 0.282 0.0275 1.48 1.4795 1.0 1257857 TimTec1_005669 OC1=C(C(C#Cc2ccccc2)C3=C(O)CCCC3=O)C(=O)CCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B16 compound treatment 0.289 0.0345 1.86 1.8556 1.0 1631021 TimTec1_005670 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3c(C)ccc4nsnc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B17 compound treatment 0.281 0.0265 1.43 1.4257 1.0 1219783 TimTec1_005671 COc1ccc(cc1)N2C(=O)NC(=O)C(Cc3ccc(O)c(OC)c3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B18 compound treatment 0.372 0.118 6.32 6.3159 1.0 3211535 TimTec1_005672 Cc1cc(NC(=O)NC(=O)c2ccc(F)cc2)n[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B19 compound treatment 0.335 0.0805 4.33 4.3276 1.0 1033315 TimTec1_005673 Cc1cc(C)n(n1)C(=S)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B20 compound treatment 0.359 0.105 5.62 5.6173 1.0 3085624 TimTec1_005674 CSc1snc(O)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B21 compound treatment 0.394 0.14 7.5 7.4981 1.0 3211536 TimTec1_005675 CCc1ccc(cc1)C2=Nn3c(C)nnc3SC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B22 compound treatment 0.488 0.234 12.55 12.5495 1.0 3085626 TimTec1_005676 O=C(Nc1cccc(c1)c2nnc(o2)c3ccco3)C(c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B23 mock treatment 0.242 -0.0125 -0.67 -0.67 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 B24 mock treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C01 compound treatment 0.413 0.159 8.52 8.5191 1.0 1675170 TimTec1_005677 C(Oc1cccc(c1)c2nnc3ccc4ccccc4n23)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C02 compound treatment 0.302 0.0475 2.55 2.5542 1.0 1346658 TimTec1_005678 Fc1ccccc1C2Nc3ccc4ccccc4c3C5C=CCC52 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C03 compound treatment 0.246 -0.00847 -0.46 -0.4551 -1.0 3085628 TimTec1_005679 COC(C)n1cc(Br)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C04 compound treatment 0.261 0.00653 0.35 0.351 1.0 1681244 TimTec1_005680 Cc1cc(Oc2cc(C#N)c3ccccc3n2)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C05 compound treatment 0.254 -4.69E-4 -0.03 -0.0252 -1.0 3085667 TimTec1_005681 Fc1ccc2C(=O)N(N3CCOCC3)C(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C06 compound treatment 0.257 0.00253 0.14 0.136 1.0 1270347 TimTec1_005682 Cn1c(=N)n(CC(=O)C2(CC3CC4CC(C3)C2)C4)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C07 compound treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 1454435 TimTec1_005683 CSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C08 compound treatment 0.258 0.00353 0.19 0.1898 1.0 1371600 TimTec1_005684 Cc1ccc(cc1)C(=O)Cn2c(=N)n(C)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C09 compound treatment 0.244 -0.0105 -0.56 -0.5626 -1.0 1605543 TimTec1_005685 CSC1=NC2(Cc3ccccc13)CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C10 compound treatment 0.499 0.245 13.14 13.1406 1.0 1564745 TimTec1_005686 CC(C)(O)C#Cc1ccc(cc1)C(=O)NCC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C11 compound treatment 0.323 0.0685 3.68 3.6827 1.0 3085653 TimTec1_005687 O=C(Nc1ccccc1)OCC23COC(N3C(OC2)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C12 compound treatment 0.267 0.0125 0.67 0.6734 1.0 1696532 TimTec1_005688 O=C1N(C(Nc2ccccc12)c3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C13 compound treatment 0.54 0.286 15.34 15.3439 1.0 3211537 TimTec1_005689 Cc1ccc(/N=C/2\NC(=O)C(Cc3cccc(c3)C(F)(F)F)S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C14 compound treatment 0.285 0.0305 1.64 1.6407 1.0 1190215 TimTec1_005690 CC(C1Nc2ccccc2C(=O)N1c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C15 compound treatment 0.282 0.0275 1.48 1.4795 1.0 1378935 TimTec1_005691 CCOC(=O)c1c(NC(=O)CSc2ncccn2)sc3CCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C16 compound treatment 0.313 0.0585 3.15 3.1453 1.0 1327450 TimTec1_005692 CCC(=O)Nc1nonc1c2nc3ccccc3n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C17 compound treatment 0.27 0.0155 0.83 0.8346 1.0 3211622 TimTec1_005693 CCC(=O)NC(Nc1sc2CCCCc2c1C#N)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C18 compound treatment 0.288 0.0335 1.8 1.8019 1.0 1168333 TimTec1_005694 CC(C)CCN1NC2(CCCCC2)NC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C19 compound treatment 0.265 0.0105 0.57 0.5659 1.0 3211623 TimTec1_005695 CN1C2=C(C(NC1=O)c3ccccc3)C(=O)N(C2)c4ccc(C)c(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C20 compound treatment 0.273 0.0185 1.0 0.9958 1.0 1532646 TimTec1_005696 Cn1nccc1C(=O)NCCN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C21 compound treatment 0.484 0.23 12.33 12.3345 1.0 1534811 TimTec1_005697 COc1c(O)ccc2c(OC)c3ccoc3nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C22 compound treatment 0.378 0.124 6.64 6.6383 1.0 3085660 TimTec1_005698 Cn1c2ccccc2c3nnc(SCc4ccc(F)cc4Cl)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C23 mock treatment 0.261 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 C24 mock treatment 0.262 0.00753 0.4 0.4047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D01 compound treatment 0.292 0.0375 2.02 2.0169 1.0 3211624 TimTec1_005699 CC1CN=C(S1)N(C(=O)Nc2ccccc2)c3ccc(OC(F)(F)F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D02 compound treatment 0.255 5.31E-4 0.03 0.0285 1.0 3085662 TimTec1_005700 C(Sc1ncn[nH]1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D03 compound treatment 0.27 0.0155 0.83 0.8346 1.0 3211625 TimTec1_005701 Cc1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccccc4)/S2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D04 compound treatment 0.273 0.0185 1.0 0.9958 1.0 3085663 TimTec1_005702 FC(F)(F)C(NCCc1c[nH]c2ccccc12)(NC(=O)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D05 compound treatment 0.278 0.0235 1.26 1.2645 1.0 3211626 TimTec1_005703 CCC1(C)OC(=Nc2ccccc21)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D06 compound treatment 0.321 0.0665 3.58 3.5753 1.0 1384761 TimTec1_005704 Oc1ccc(NC2=C(C(=O)c3ccccc3C2=O)n4nnc5ccccc45)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D07 compound treatment 0.258 0.00353 0.19 0.1898 1.0 1725838 TimTec1_005705 CSc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ccc5ccccc5c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D08 compound treatment 0.275 0.0205 1.1 1.1033 1.0 1630880 TimTec1_005706 Cn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D09 compound treatment 0.289 0.0345 1.86 1.8556 1.0 1339859 TimTec1_005707 COc1cc2ccccc2cc1C(=O)NCCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D10 compound treatment 0.261 0.00653 0.35 0.351 1.0 1488964 TimTec1_005708 CC(C)(C)c1ccc(cc1)C23OC(=O)C(C)(C)C3OC(=O)C2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D11 compound treatment 0.258 0.00353 0.19 0.1898 1.0 1458934 TimTec1_005709 C1CN(CCN1)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D12 compound treatment 0.492 0.238 12.76 12.7644 1.0 3211627 TimTec1_005710 O=C/1NC(=S)N\C1=C\c2cc3ccccc3nc2N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D13 compound treatment 0.29 0.0355 1.91 1.9094 1.0 1617853 TimTec1_005711 Cc1cccc(C)c1NC(=O)C2(CCCC2)N(Cc3ccccc3)C(=O)c4ccc(cc4)n5cnnn5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D14 compound treatment 0.258 0.00353 0.19 0.1898 1.0 1422235 TimTec1_005712 Brc1ccc(CC2(CCc3ccncc3)C(=O)NC(=O)NC2=O)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D15 compound treatment 0.378 0.124 6.64 6.6383 1.0 3211628 TimTec1_005713 CCN(CC)c1ccc(cc1)C2(NN(C(=C2C#N)N)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D16 compound treatment 0.327 0.0725 3.9 3.8977 1.0 3085673 TimTec1_005714 C/C(=N\c1ccccc1)/C2=C(O)C=C(CC2c3ccco3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D17 compound treatment 0.262 0.00753 0.4 0.4047 1.0 3211629 TimTec1_005715 Fc1ccc(CCN2C(=O)NC(=O)/C(=C\c3cccc4ccccc34)/C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D18 compound treatment 0.623 0.369 19.8 19.8041 1.0 1524909 TimTec1_005716 COc1ccccc1c2nnc(o2)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D19 compound treatment 0.381 0.127 6.8 6.7995 1.0 3211630 TimTec1_005717 COc1cccc(c1)c2cc(nc(SC3CC(=O)C4OCC3O4)n2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D20 compound treatment 0.262 0.00753 0.4 0.4047 1.0 3085676 TimTec1_005718 FC(F)(F)c1cccc(c1)N2C(=O)CC(Cc3ccccc3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D21 compound treatment 0.289 0.0345 1.86 1.8556 1.0 3211631 TimTec1_005719 CC1(C)OC(=O)C(=Cc2cccn2c3ccc(cc3)S(=O)(=O)N)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D22 compound treatment 0.362 0.108 5.78 5.7785 1.0 3085679 TimTec1_005720 Cc1cccc2nc(=S)n(C(=O)c3ccc(F)cc3)n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D23 mock treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 D24 mock treatment 0.257 0.00253 0.14 0.136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E01 compound treatment 0.274 0.0195 1.05 1.0496 1.0 3211632 TimTec1_005721 Cc1cc(F)c(F)c(C(=O)n2ccnc2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E02 compound treatment 0.258 0.00353 0.19 0.1898 1.0 1584802 TimTec1_005722 O=C(CSc1ccccc1)Nc2c(oc3ccccc23)C(=O)C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E03 compound treatment 0.287 0.0325 1.75 1.7482 1.0 3211633 TimTec1_005723 COCc1cc(C)nc2sc(C(=O)OC)c(N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E04 compound treatment 0.363 0.109 5.83 5.8322 1.0 3211634 TimTec1_005724 CC(C)COC(=O)C1=C(C)Nc2cc(ccc2S1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E05 compound treatment 0.273 0.0185 1.0 0.9958 1.0 3085682 TimTec1_005725 Fc1ccc(COc2ccccc2/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E06 compound treatment 0.403 0.149 7.98 7.9818 1.0 3211635 TimTec1_005726 CN(C)c1ccc(/C=C\2/Oc3c(ccc(O)c3O)C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E07 compound treatment 0.314 0.0595 3.2 3.1991 1.0 3211636 TimTec1_005727 CCn/1c(cs\c1=N\c2cc(OC)c(Cl)cc2OC)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E08 compound treatment 0.261 0.00653 0.35 0.351 1.0 1668810 TimTec1_005728 N=C1OC23CCCCC3C(C#N)(C#N)C1(C#N)C(Cc4ccccc4)O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E09 compound treatment 0.265 0.0105 0.57 0.5659 1.0 1468867 TimTec1_005729 NS(=O)(=O)c1ccc(N=NN2CCCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E10 compound treatment 0.315 0.0605 3.25 3.2528 1.0 1221615 TimTec1_005730 CCc1ccc2cc(cn2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E11 compound treatment 0.278 0.0235 1.26 1.2645 1.0 3211637 TimTec1_005731 CC1SC(N(C1=O)c2ccccc2)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E12 compound treatment 0.257 0.00253 0.14 0.136 1.0 1203111 TimTec1_005732 Cc1cc(C(=O)O)c(C#N)c(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E13 compound treatment 0.308 0.0535 2.88 2.8767 1.0 3211638 TimTec1_005733 NC(=NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E14 compound treatment 0.263 0.00853 0.46 0.4585 1.0 3085709 TimTec1_005734 Cc1nc2ccccc2c(=O)n1c3ccc4OC(F)(F)Oc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E15 compound treatment 0.265 0.0105 0.57 0.5659 1.0 3085711 TimTec1_005735 C/C(=C/C(=O)C1CC1)/C2CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E16 compound treatment 0.461 0.207 11.1 11.0986 1.0 1198283 TimTec1_005736 CC(C(=O)Nc1ccc2OCCOc2c1)n3nnc(n3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E17 compound treatment 0.284 0.0295 1.59 1.5869 1.0 1200453 TimTec1_005737 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E18 compound treatment 0.295 0.0405 2.18 2.1781 1.0 1488913 TimTec1_005738 CCCc1cc(O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E19 compound treatment 0.289 0.0345 1.86 1.8556 1.0 1378082 TimTec1_005739 CCOC(=O)C1(CCN(CC1)C(=O)c2ccccc2O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E20 compound treatment 0.262 0.00753 0.4 0.4047 1.0 1283200 TimTec1_005740 CC(C)N1C2OC(OC2N(C(C)C)S1(=O)=O)C3OC4C(O3)N(C(C)C)S(=O)(=O)N4C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E21 compound treatment 0.356 0.102 5.46 5.4561 1.0 1315806 TimTec1_005741 CC(=O)Oc1ccc(C)cc1n2nc3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E22 compound treatment 0.296 0.0415 2.23 2.2318 1.0 3085715 TimTec1_005742 COc1ccccc1N/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E23 mock treatment 0.262 0.00753 0.4 0.4047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 E24 mock treatment 0.267 0.0125 0.67 0.6734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F01 compound treatment 0.28 0.0255 1.37 1.372 1.0 1415787 TimTec1_005743 O=C(Cn1nnc(n1)c2ccc3OCOc3c2)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F02 compound treatment 0.494 0.24 12.87 12.8719 1.0 1291024 TimTec1_005744 Cc1[nH]c2ccccc2c1CCNC(=O)c3cc4cc(Br)ccc4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F03 compound treatment 0.487 0.233 12.5 12.4957 1.0 3085718 TimTec1_005745 FC(F)(F)c1nnc(S)n1/N=C/c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F04 compound treatment 0.475 0.221 11.85 11.8509 1.0 1647381 TimTec1_005746 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F05 compound treatment 0.27 0.0155 0.83 0.8346 1.0 1416263 TimTec1_005747 Cc1c(NC(=O)C2CCCC2)c(=O)n(c3ccccc3)n1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F06 compound treatment 0.288 0.0335 1.8 1.8019 1.0 3211747 TimTec1_005748 Cc1cc(S)c2n(Cc3ccc(Cl)cc3Cl)nc[n+]2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F07 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1581088 TimTec1_005749 Fc1cccc(Cl)c1C2N3CCCCN23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F08 compound treatment 0.527 0.273 14.65 14.6453 1.0 1406168 TimTec1_005750 COC(=O)c1ccc(CSc2nnc3c4ccccc4n(C)c3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F09 compound treatment 0.308 0.0535 2.88 2.8767 1.0 3211748 TimTec1_005751 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)Nc3nn(nc3C(=O)N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F10 compound treatment 0.257 0.00253 0.14 0.136 1.0 3087784 TimTec1_005752 CC1(NC(C2C1C(=O)N(C2=O)c3ccccc3)c4cc(Br)ccc4O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F11 compound treatment 0.27 0.0155 0.83 0.8346 1.0 3211749 TimTec1_005753 N#CCC1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F12 compound treatment 0.288 0.0335 1.8 1.8019 1.0 1605647 TimTec1_005754 COc1ccc(cc1OC)C2C(Oc3ccc(Cl)cc3C)C(=O)N2c4ccc(C)c(C)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F13 compound treatment 0.262 0.00753 0.4 0.4047 1.0 3087785 TimTec1_005755 C[S+](C)c1c(O)n(c2ccccc2F)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F14 compound treatment 0.257 0.00253 0.14 0.136 1.0 1201797 TimTec1_005756 Fc1cc(Cl)c(cc1F)C(=O)NC2C3CC4CC(C3)CC2C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F15 compound treatment 0.262 0.00753 0.4 0.4047 1.0 1326307 TimTec1_005757 CC(Sc1nc(N)cc(N)n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F16 compound treatment 0.323 0.0685 3.68 3.6827 1.0 1664927 TimTec1_005758 C=CCn1c2ccccc2c3nnc(SCc4ccc5nonc5c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F17 compound treatment 0.258 0.00353 0.19 0.1898 1.0 3087786 TimTec1_005759 CC(Nc1nc(F)cc(=O)[nH]1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F18 compound treatment 0.311 0.0565 3.04 3.0379 1.0 3211750 TimTec1_005760 CCOC(=O)/C=C/1\NC(C)(C)Cc2cc(OC)c(O)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F19 compound treatment 0.324 0.0695 3.74 3.7365 1.0 3211751 TimTec1_005761 O=C(CSc1nnnn1c2ccccc2)NCCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F20 compound treatment 0.277 0.0225 1.21 1.2108 1.0 3087787 TimTec1_005762 CC1SC2(CCCCC2)N(C1=O)c3cc(C)cc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F21 compound treatment 0.273 0.0185 1.0 0.9958 1.0 3211752 TimTec1_005763 CC(=O)NC(NCCC1(CC2CC3CC(C2)C1)C3)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F22 compound treatment 0.452 0.198 10.61 10.6149 1.0 1523330 TimTec1_005764 O=C(Oc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F23 mock treatment 0.274 0.0195 1.05 1.0496 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 F24 mock treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G01 compound treatment 0.296 0.0415 2.23 2.2318 1.0 3087788 TimTec1_005765 Fc1ccccc1c2nnc3ccc(cn23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G02 compound treatment 0.238 -0.0165 -0.88 -0.885 -1.0 3211753 TimTec1_005766 CN1C(=O)N(C)C2(N=C3SCC(=O)N3NC12c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G03 compound treatment 0.264 0.00953 0.51 0.5122 1.0 1444799 TimTec1_005767 OC1=C(C(N(C1=O)c2cccnc2)c3ccccc3)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G04 compound treatment 0.25 -0.00447 -0.24 -0.2401 -1.0 1457617 TimTec1_005768 O=C(N1N=CCC1c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G05 compound treatment 0.54 0.286 15.34 15.3439 1.0 1406350 TimTec1_005769 Clc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc45)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G06 compound treatment 0.277 0.0225 1.21 1.2108 1.0 1302719 TimTec1_005770 COC(=O)c1ccccc1NCNc2ccccc2C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G07 compound treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 1261268 TimTec1_005771 CCCC(=C1C(=O)NC(=O)NC1=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G08 compound treatment 0.278 0.0235 1.26 1.2645 1.0 1028239 TimTec1_005772 S=c1sscc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G09 compound treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 3211754 TimTec1_005773 CCOC(=O)Cc1nc(C)cs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G10 compound treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 1366551 TimTec1_005774 CCC1C(OC(=O)C(C)(C)C1=O)c2cccc(Br)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G11 compound treatment 0.239 -0.0155 -0.83 -0.8313 -1.0 3087789 TimTec1_005775 CC(=O)OC(C)(C)C#CCN1CCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G12 compound treatment 0.318 0.0635 3.41 3.414 1.0 3211755 TimTec1_005776 O=C/1Nc2ccccc2\C1=C/3\NC(=S)N(C3=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G13 compound treatment 0.26 0.00553 0.3 0.2972 1.0 3087790 TimTec1_005777 CCOC1=NOC2C3CCC(C3)C21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G14 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 3211756 TimTec1_005778 COc1ccc(cc1)C2OCC(C)(CO2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G15 compound treatment 0.259 0.00453 0.24 0.2435 1.0 3087791 TimTec1_005779 Nc1ccc(OC(F)(F)F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G16 compound treatment 0.512 0.258 13.84 13.8392 1.0 1233416 TimTec1_005780 C(Sc1nnnn1c2ccc3OCOc3c2)C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G17 compound treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 1922264 TimTec1_005781 CC1(C)COC(O)(CC1=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G18 compound treatment 0.288 0.0335 1.8 1.8019 1.0 1589793 TimTec1_005782 CCc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(cc4)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G19 compound treatment 0.263 0.00853 0.46 0.4585 1.0 3087792 TimTec1_005783 CSC1=NC2C(N1)N(C)C(=O)N2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G20 compound treatment 0.299 0.0445 2.39 2.393 1.0 1362774 TimTec1_005784 N=C1OC23CCCCC3C(C#N)(C#N)C1(C#N)C(O2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G21 compound treatment 0.268 0.0135 0.73 0.7271 1.0 3087793 TimTec1_005785 O=C(Oc1ccc(cc1)c2cnc3ccccc3n2)/C=C/c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G22 compound treatment 0.384 0.13 6.96 6.9607 1.0 1511555 TimTec1_005786 Clc1ccc2oc(=O)n(C(=O)NC3CCCCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G23 mock treatment 0.256 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 G24 mock treatment 0.254 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H01 compound treatment 0.304 0.0495 2.66 2.6617 1.0 1788039 TimTec1_005787 Fc1ccccc1c2nnn(CC(=O)N3CCCCC3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H02 compound treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 1578958 TimTec1_005788 COc1ccc(Cl)cc1S(=O)(=O)N2CCN(CC2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H03 compound treatment 0.265 0.0105 0.57 0.5659 1.0 3087794 TimTec1_005789 COc1cc2CC(C)(C)N=C(NC(C)C(=O)O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H04 compound treatment 0.295 0.0405 2.18 2.1781 1.0 3087795 TimTec1_005790 NCCN1C(=O)S/C(=C/c2cccs2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H05 compound treatment 0.271 0.0165 0.89 0.8884 1.0 1701075 TimTec1_005791 CCn1c(=N)n(CC(=O)c2cccs2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H06 compound treatment 0.294 0.0395 2.12 2.1243 1.0 1332043 TimTec1_005792 COC(=O)NC1CSCC1OC(=O)CCCN2C(=O)c3ccccc3C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H07 compound treatment 0.286 0.0315 1.69 1.6944 1.0 3087798 TimTec1_005793 COc1nsc(SC)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H08 compound treatment 0.377 0.123 6.58 6.5846 1.0 1015156 TimTec1_005794 COc1ccc(Cl)cc1NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H09 compound treatment 0.461 0.207 11.1 11.0986 1.0 1397048 TimTec1_005795 COc1cc2ccccc2cc1C(=O)NC(C)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H10 compound treatment 0.313 0.0585 3.15 3.1453 1.0 3087801 TimTec1_005796 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4c(F)cccc4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H11 compound treatment 0.281 0.0265 1.43 1.4257 1.0 1338227 TimTec1_005797 COc1ccc(NC(=O)c2cnn(c2NC(=O)c3ccccc3F)c4ccccc4)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H12 compound treatment 0.292 0.0375 2.02 2.0169 1.0 1493728 TimTec1_005798 C1Oc2ccc(cc2O1)c3cc4ccccn4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H13 compound treatment 0.316 0.0615 3.31 3.3066 1.0 1440128 TimTec1_005799 COc1cc(NC(=O)NC2(CC2)c3ccccc3)c(OC)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H14 compound treatment 0.299 0.0445 2.39 2.393 1.0 1272978 TimTec1_005800 Cc1cc(NS(=O)(=O)c2ccccc2)cc(c1O)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H15 compound treatment 0.293 0.0385 2.07 2.0706 1.0 3211757 TimTec1_005801 Cc1cc(Cl)nc(NN)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H16 compound treatment 0.429 0.175 9.38 9.3789 1.0 1520603 TimTec1_005802 Cn1c2ccc(Br)cc2c3nnc(SCc4ccc5nonc5c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H17 compound treatment 0.379 0.125 6.69 6.692 1.0 1486800 TimTec1_005803 CN(C)CP(=O)(O)CCn1c2ccccc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H18 compound treatment 0.332 0.0775 4.17 4.1664 1.0 1194716 TimTec1_005804 OC(=O)C1Sc2c(sc(=O)n2Cc3ccccc3)C4C1C(=O)Oc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H19 compound treatment 0.474 0.22 11.8 11.7972 1.0 1203354 TimTec1_005805 Nc1nnc(CCCn2c(=O)oc3ccccc23)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H20 compound treatment 0.386 0.132 7.07 7.0682 1.0 3087859 TimTec1_005806 CC/N=C\1/S/C(=C/c2ccc(o2)c3ccc(F)cc3)/C(=O)N1CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H21 compound treatment 0.263 0.00853 0.46 0.4585 1.0 1544104 TimTec1_005807 CN(C)c1ccc(cc1)C2OC(=O)C(C)(C)C(=O)C2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H22 compound treatment 0.421 0.167 8.95 8.949 1.0 3211853 TimTec1_005808 CCCn1c2ccccc2c3nnc(SCC(=O)NCc4ccc5OCOc5c4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H23 mock treatment 0.245 -0.00947 -0.51 -0.5088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 H24 mock treatment 0.256 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I01 compound treatment 0.257 0.00253 0.14 0.136 1.0 1315061 TimTec1_005809 CCOC1(C)N(Nc2ccccc2C(=O)CC)c3ccccc3C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I02 compound treatment 0.24 -0.0145 -0.78 -0.7775 -1.0 1011005 TimTec1_005810 OC(=O)CSc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I03 compound treatment 0.239 -0.0155 -0.83 -0.8313 -1.0 3211854 TimTec1_005811 CC1(C)OC(=O)N(Nc2ccccc2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I04 compound treatment 0.407 0.153 8.2 8.1967 1.0 3087863 TimTec1_005812 Cc1c(Cl)cccc1NN 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I05 compound treatment 0.504 0.25 13.41 13.4093 1.0 1462704 TimTec1_005813 CC(C)(C)NC(=O)CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I06 compound treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 1663326 TimTec1_005814 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)Nc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I07 compound treatment 0.523 0.269 14.43 14.4303 1.0 3211855 TimTec1_005815 C1C/C(=C\c2nc3ccccc3[nH]2)/C(=C1)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I08 compound treatment 0.262 0.00753 0.4 0.4047 1.0 1375813 TimTec1_005816 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I09 compound treatment 0.245 -0.00947 -0.51 -0.5088 -1.0 3087867 TimTec1_005817 COC(=O)c1c(CSC(=N)N)nc2n(Cc3ccccc3)c4ccccc4n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I10 compound treatment 0.261 0.00653 0.35 0.351 1.0 3211856 TimTec1_005818 CC1=C(OC(=O)c2ccccc2)C(C)(C)C(OC1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I11 compound treatment 0.266 0.0115 0.62 0.6197 1.0 3087868 TimTec1_005819 COC(=O)c1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I12 compound treatment 0.271 0.0165 0.89 0.8884 1.0 3211857 TimTec1_005820 COc1ccc(/C=N/c2nnc(c3ccccc3)c(n2)c4ccccc4)c(C(=O)O)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I13 compound treatment 0.497 0.243 13.03 13.0331 1.0 3087871 TimTec1_005821 CC1CN(CN2C(=O)/C(=N\c3ccc4ccccc4c3)/c5ccccc25)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I14 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1190190 TimTec1_005822 CC(=O)OC1c2ccccc2NC(c3ccccc3)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I15 compound treatment 0.289 0.0345 1.86 1.8556 1.0 1442650 TimTec1_005823 COC(=O)C1=C(C)NC(=C(C#N)C1c2cccs2)SCC(=O)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I16 compound treatment 0.336 0.0815 4.38 4.3813 1.0 3087873 TimTec1_005824 SC1=C(C#N)C2(CCCCC2)C(C(=N)N1)c3nc(cs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I17 compound treatment 0.273 0.0185 1.0 0.9958 1.0 1201213 TimTec1_005825 OC(=O)c1ccc(N=NN2CCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I18 compound treatment 0.366 0.112 5.99 5.9935 1.0 3211858 TimTec1_005826 CSc1ccc(cc1)S(=O)(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I19 compound treatment 0.264 0.00953 0.51 0.5122 1.0 1656330 TimTec1_005827 CC(C)(CN1CCN(CC1)C(c2ccccc2)c3ccccc3)NS(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I20 compound treatment 0.324 0.0695 3.74 3.7365 1.0 1594685 TimTec1_005828 CC1C(C#N)(C#N)C2(C#N)C(OC1(C)OC2=N)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I21 compound treatment 0.3 0.0455 2.45 2.4468 1.0 3211859 TimTec1_005829 O=C/1N(CN2CCN(CC2)c3ccccc3)c4ccccc4\C1=N\c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I22 compound treatment 0.454 0.2 10.72 10.7224 1.0 1426903 TimTec1_005830 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(O)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I23 mock treatment 0.258 0.00353 0.19 0.1898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 I24 mock treatment 0.268 0.0135 0.73 0.7271 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J01 compound treatment 0.246 -0.00847 -0.46 -0.4551 -1.0 1380440 TimTec1_005831 CC(C)(CO)NC1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J02 compound treatment 0.256 0.00153 0.08 0.0823 1.0 1328534 TimTec1_005832 Clc1ccc(Cl)c(c1)S(=O)(=O)NCCC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J03 compound treatment 0.256 0.00153 0.08 0.0823 1.0 3211860 TimTec1_005833 FC(F)(F)C1=CC(=NCCN1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J04 compound treatment 0.282 0.0275 1.48 1.4795 1.0 1159735 TimTec1_005834 CN(C)P1(=O)Nc2ccccc2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J05 compound treatment 0.254 -4.69E-4 -0.03 -0.0252 -1.0 1421447 TimTec1_005835 CC(C)(O)C1(C)NCCc2ccccc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J06 compound treatment 0.27 0.0155 0.83 0.8346 1.0 1178221 TimTec1_005836 CC1CC2(CC(C)(C)C1)NN(C(=S)N2)c3ccc(C)c(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J07 compound treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 1709992 TimTec1_005837 CC1(C)CC(CC(C)(C)N1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J08 compound treatment 0.261 0.00653 0.35 0.351 1.0 1603180 TimTec1_005838 O=C(NC1CCCCC1)C2CC(=O)OC32CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J09 compound treatment 0.275 0.0205 1.1 1.1033 1.0 1526847 TimTec1_005839 Cc1ccc2c3C(C4=C(CCCC4=O)Nc3ccc2n1)c5ccccc5C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J10 compound treatment 0.289 0.0345 1.86 1.8556 1.0 3211861 TimTec1_005840 CCc1nc2sc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c(N)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J11 compound treatment 0.482 0.228 12.23 12.2271 1.0 1564041 TimTec1_005841 CCN(C(=O)Cn1nnc(n1)c2ccc3OCOc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J12 compound treatment 0.356 0.102 5.46 5.4561 1.0 3087925 TimTec1_005842 FC(F)(F)c1nnc2SCC(=Nn12)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J13 compound treatment 0.261 0.00653 0.35 0.351 1.0 3211862 TimTec1_005843 CCN1C(=O)C2NN=C(C2C1=O)C(=O)c3nc(Cl)ccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J14 compound treatment 0.357 0.103 5.51 5.5098 1.0 1209557 TimTec1_005844 COc1ccc(cc1)C(=O)Nc2cc(C)c(O)c(c2C)S(=O)(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J15 compound treatment 0.324 0.0695 3.74 3.7365 1.0 3211863 TimTec1_005845 Sc1nc(SCCOc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J16 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 3087928 TimTec1_005846 CC(C)(C)C(=O)/C=C/1\NCCN\C1=C/C(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J17 compound treatment 0.259 0.00453 0.24 0.2435 1.0 1272266 TimTec1_005847 OC(=O)C(Cc1ccco1)P(=O)(O)CN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J18 compound treatment 0.328 0.0735 3.95 3.9514 1.0 1688384 TimTec1_005848 O=C(Nc1ccccc1)c2cccc(c2)S(=O)(=O)NCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J19 compound treatment 0.309 0.0545 2.93 2.9304 1.0 1696945 TimTec1_005849 COc1cccc(c1)C(=O)Nc2cccc(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J20 compound treatment 0.305 0.0505 2.72 2.7154 1.0 3087931 TimTec1_005850 Cc1cccn2cc(cc12)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J21 compound treatment 0.278 0.0235 1.26 1.2645 1.0 1142933 TimTec1_005851 Cc1ccc(cc1)C(=O)C2OC(=O)C(C)(C)C(=O)C2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J22 compound treatment 0.363 0.109 5.83 5.8322 1.0 3211864 TimTec1_005852 COc1cccc2cc(C(=O)NCCc3c(C)[nH]c4ccc(OC(F)(F)F)cc34)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J23 mock treatment 0.244 -0.0105 -0.56 -0.5626 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 J24 mock treatment 0.247 -0.00747 -0.4 -0.4014 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K01 compound treatment 0.351 0.0965 5.19 5.1874 1.0 1683560 TimTec1_005853 CCn1c(nc2ccccc12)C(O)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K02 compound treatment 0.262 0.00753 0.4 0.4047 1.0 3088026 TimTec1_005854 O=C1CSC2=NCN(CN12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K03 compound treatment 0.249 -0.00547 -0.29 -0.2939 -1.0 3087964 TimTec1_005855 CCOC(=O)C1=C(C)NC(=NC1c2ccc(OC(=O)C)c(OC)c2)SC(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K04 compound treatment 0.281 0.0265 1.43 1.4257 1.0 3087966 TimTec1_005856 CC(=O)NCCOc1cccc2cccnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K05 compound treatment 0.406 0.152 8.14 8.143 1.0 1264565 TimTec1_005857 Cn1c(SCc2ccc(F)c3ccccc23)nc4ccccc4c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K06 compound treatment 0.254 -4.69E-4 -0.03 -0.0252 -1.0 3211865 TimTec1_005858 Clc1ccc(/N=C/2\C(=O)N(CN3CCc4ccccc4C3)c5ccccc25)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K07 compound treatment 0.258 0.00353 0.19 0.1898 1.0 1638757 TimTec1_005859 CCN(CC)P1(=O)COc2ccccc2OC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K08 compound treatment 0.289 0.0345 1.86 1.8556 1.0 3211945 TimTec1_005860 CCC1CCC2(CC1)SCC(=O)N2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K09 compound treatment 0.368 0.114 6.1 6.1009 1.0 1385466 TimTec1_005861 COc1ccc(cc1)N(C)C(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K10 compound treatment 0.27 0.0155 0.83 0.8346 1.0 1301245 TimTec1_005862 Cc1ccc(NS(=O)(=O)c2c(C)ccc3nsnc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K11 compound treatment 0.336 0.0815 4.38 4.3813 1.0 3087971 TimTec1_005863 CN(C)/C=N\c1ccc2nonc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K12 compound treatment 0.293 0.0385 2.07 2.0706 1.0 1432844 TimTec1_005864 CCOC(=O)c1c(CN2CCCC2)n(C)c3cc(Br)c(OC)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K13 compound treatment 0.262 0.00753 0.4 0.4047 1.0 3211946 TimTec1_005865 CSC1=NC2(CC(Oc3cc(O)ccc32)c4ccccc4)CC(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K14 compound treatment 0.568 0.314 16.85 16.8485 1.0 3087973 TimTec1_005866 CC(=O)N1C(=O)/C(=C\c2cccnc2)/NC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K15 compound treatment 0.413 0.159 8.52 8.5191 1.0 1685221 TimTec1_005867 CCOC(=O)c1c(NC(=O)CSc2nccn2C)sc3CC(C)CCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K16 compound treatment 0.242 -0.0125 -0.67 -0.67 -1.0 3087975 TimTec1_005868 Oc1ccccc1c2cc(nn2Cc3ccc(Cl)cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K17 compound treatment 0.407 0.153 8.2 8.1967 1.0 1551420 TimTec1_005869 COC(=O)c1ccc(N=NN2CCCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K18 compound treatment 0.306 0.0515 2.77 2.7692 1.0 1545682 TimTec1_005870 COc1ccc(cc1)C2CC(=O)Oc3ccc(cc23)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K19 compound treatment 0.266 0.0115 0.62 0.6197 1.0 1253632 TimTec1_005871 O=C(N(Cc1ccccc1)c2ccccn2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K20 compound treatment 0.53 0.276 14.81 14.8065 1.0 3211947 TimTec1_005872 COc1nc(OC)nc(n1)n2cnc(NC(=O)Nc3cccc(Cl)c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K21 compound treatment 0.302 0.0475 2.55 2.5542 1.0 1118061 TimTec1_005873 Sc1nc2-c3ccccc3CC(C4CCCCC4)c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K22 compound treatment 0.272 0.0175 0.94 0.9421 1.0 3211948 TimTec1_005874 CCC(C#N)C1(CC2CC3CC(C2)C1)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K23 mock treatment 0.249 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 K24 mock treatment 0.26 0.00553 0.3 0.2972 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L01 compound treatment 0.279 0.0245 1.32 1.3183 1.0 3087980 TimTec1_005875 COC(=O)c1ccc(cc1)C2OCC(C)(C)CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L02 compound treatment 0.406 0.152 8.14 8.143 1.0 1135137 TimTec1_005876 CCOc1ccc(CCNS(=O)(=O)c2c(C)cc(C)cc2C)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L03 compound treatment 0.295 0.0405 2.18 2.1781 1.0 3211949 TimTec1_005877 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L04 compound treatment 0.289 0.0345 1.86 1.8556 1.0 1515423 TimTec1_005878 CCOc1nc(Cl)nc(n1)N2CCCCC2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L05 compound treatment 0.266 0.0115 0.62 0.6197 1.0 3088028 TimTec1_005879 COc1ccc(cc1)C(=O)NC(N2CCCCC2c3cccnc3)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L06 compound treatment 0.264 0.00953 0.51 0.5122 1.0 1732675 TimTec1_005880 CCOc1ccc(CC(=O)Nc2ccccc2)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L07 compound treatment 0.376 0.122 6.53 6.5308 1.0 1230635 TimTec1_005881 Cc1ccc2c3C(C4=C(CCCC4=O)Nc3ccc2n1)c5ccc(O)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L08 compound treatment 0.257 0.00253 0.14 0.136 1.0 1233176 TimTec1_005882 CCNC(=O)C1CC(=O)OC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L09 compound treatment 0.475 0.221 11.85 11.8509 1.0 1157682 TimTec1_005883 COCc1cc(C)nc(SCC(=O)N2CCCCC2)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L10 compound treatment 0.259 0.00453 0.24 0.2435 1.0 3088032 TimTec1_005884 CC(=O)ON1C(C)(C)C=C(C(=O)N)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L11 compound treatment 0.284 0.0295 1.59 1.5869 1.0 3211950 TimTec1_005885 COc1ccccc1n2c(S)nnc2Cc3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L12 compound treatment 0.287 0.0325 1.75 1.7482 1.0 1274328 TimTec1_005886 COc1ccccc1C2C3=C(CCCC3=O)Nc4ccc5ncccc5c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L13 compound treatment 0.264 0.00953 0.51 0.5122 1.0 3211951 TimTec1_005887 COC(=O)C1=CN(CC2(CC3CC4CC(C3)C2)C4)C=C(C1c5ccc(F)cc5)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L14 compound treatment 0.31 0.0555 2.98 2.9841 1.0 1513069 TimTec1_005888 CC(C)c1c(NC(=O)c2ccc(Cl)cc2)cc(C)c(O)c1S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L15 compound treatment 0.297 0.0425 2.29 2.2855 1.0 1273520 TimTec1_005889 CCn1c(SCCn2c(=S)n(C)c3ccccc23)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L16 compound treatment 0.261 0.00653 0.35 0.351 1.0 1715744 TimTec1_005890 C(N1CCCC1)c2cc3ccccc3c4COCc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L17 compound treatment 0.343 0.0885 4.76 4.7575 1.0 1402014 TimTec1_005891 Cc1nc2cccc(C(=O)Oc3ccc(cc3)C(C)(C)C)c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L18 compound treatment 0.359 0.105 5.62 5.6173 1.0 1594146 TimTec1_005892 O=C(Nc1ccccc1)c2cccc(c2)S(=O)(=O)NCCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L19 compound treatment 0.563 0.309 16.58 16.5798 1.0 3088038 TimTec1_005893 CCc1nnc(NC(=O)CSc2nnc(c3cccs3)n2CC=C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L20 compound treatment 0.453 0.199 10.67 10.6687 1.0 3211952 TimTec1_005894 CCN(CC)c1ccc(C=C2C(=O)OC(OC2=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L21 compound treatment 0.372 0.118 6.32 6.3159 1.0 3088039 TimTec1_005895 OC(=O)/C(=C/C(=O)c1ccccc1)/Nc2ccc(OC(F)(F)F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L22 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1788194 TimTec1_005896 CCOC(=O)c1c(C)c(NC(=O)C)c(C)n1C(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L23 mock treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 L24 mock treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M01 compound treatment 0.435 0.181 9.7 9.7014 1.0 1430182 TimTec1_005897 Cc1cc(NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccc(C)cc3)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M02 compound treatment 0.25 -0.00447 -0.24 -0.2401 -1.0 1516860 TimTec1_005898 CCN1C2OC3OC4C(OC3OC2N(CC)S1(=O)=O)N(CC)S(=O)(=O)N4CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M03 compound treatment 0.281 0.0265 1.43 1.4257 1.0 1315988 TimTec1_005899 Clc1ccccc1NCn2nc(c3ccccc3)n(CC=C)c2=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M04 compound treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 3088042 TimTec1_005900 CCC(=O)NC(Nc1sc(C)c(CC)c1C#N)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M05 compound treatment 0.283 0.0285 1.53 1.5332 1.0 3211953 TimTec1_005901 CC(C)C1C(=C(N)Oc2n[nH]c(C)c12)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M06 compound treatment 0.356 0.102 5.46 5.4561 1.0 1171314 TimTec1_005902 COc1ccc(OC)c(CNc2ccc3n(C)c(C)nc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M07 compound treatment 0.275 0.0205 1.1 1.1033 1.0 3088045 TimTec1_005903 CCOC(=O)C1=C(C)NC(=NC1c2ccccc2)SCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M08 compound treatment 0.275 0.0205 1.1 1.1033 1.0 1705094 TimTec1_005904 OC(=O)Cc1c(Sc2ccccc2)c3ccccc3n1Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M09 compound treatment 0.272 0.0175 0.94 0.9421 1.0 3211954 TimTec1_005905 CN(C)c1ccc(/C=C/2\C(=O)N(N=C2C(=O)Nc3ccccc3)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M10 compound treatment 0.245 -0.00947 -0.51 -0.5088 -1.0 1621165 TimTec1_005906 O1c2ccccc2N=C(c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M11 compound treatment 0.233 -0.0215 -1.15 -1.1537 -1.0 1640716 TimTec1_005907 CCN(CC)C(=O)c1cn(nc1C2(CC3CC4CC(C3)C2)C4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M12 compound treatment 0.267 0.0125 0.67 0.6734 1.0 3211955 TimTec1_005908 OC(=O)C1CC(=O)N(CCc2ccccc2)/C(=N/CCc3ccccc3)/S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M13 compound treatment 0.45 0.196 10.51 10.5074 1.0 3088114 TimTec1_005909 CCCN1C(=O)/C(=C/C=C\2/Sc3ccccc3N2CCO)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M14 compound treatment 0.321 0.0665 3.58 3.5753 1.0 1416853 TimTec1_005910 CCCCC(=O)Nc1ccc(cc1)c2csc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M15 compound treatment 0.283 0.0285 1.53 1.5332 1.0 3088116 TimTec1_005911 FC(F)(F)c1cccc(/N=C/2\C(=O)N(CN3CCc4ccccc4C3)c5ccccc25)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M16 compound treatment 0.386 0.132 7.07 7.0682 1.0 1117685 TimTec1_005912 CN(C)c1ccc(cc1)C2OC(COc3ccccc3)CN(O2)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M17 compound treatment 0.261 0.00653 0.35 0.351 1.0 1411622 TimTec1_005913 O=C(N(c1ccccc1)c2ccccc2)c3ccccc3C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M18 compound treatment 0.548 0.294 15.77 15.7738 1.0 1119974 TimTec1_005914 COc1ccc(cc1)c2nc(SCc3ccccc3C#N)[nH]c(=O)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M19 compound treatment 0.352 0.0975 5.24 5.2411 1.0 1518985 TimTec1_005915 CC(C1C(=C(N)Oc2c1c(=O)oc3ccccc23)C#N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M20 compound treatment 0.284 0.0295 1.59 1.5869 1.0 3088119 TimTec1_005916 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M21 compound treatment 0.26 0.00553 0.3 0.2972 1.0 1232476 TimTec1_005917 CC1CN(C(=O)C)c2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M22 compound treatment 0.271 0.0165 0.89 0.8884 1.0 1452888 TimTec1_005918 O=C1N(C(=O)c2cccc3cccc1c23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M23 mock treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 M24 mock treatment 0.257 0.00253 0.14 0.136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N01 compound treatment 0.261 0.00653 0.35 0.351 1.0 1241281 TimTec1_005919 COc1cc(NC(=O)c2cc3ccccc3cc2OCC(=O)NC(C)(C)C)c(OC)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N02 compound treatment 0.261 0.00653 0.35 0.351 1.0 3088122 TimTec1_005920 CCn/1cccc\c1=N/P2(=S)OCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N03 compound treatment 0.428 0.174 9.33 9.3252 1.0 1595949 TimTec1_005921 OC1=C(C(N(CCc2ccccc2)C1=O)c3ccccc3)C(=O)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N04 compound treatment 0.267 0.0125 0.67 0.6734 1.0 1572095 TimTec1_005922 COCc1cc(C)nc2[nH]nc(N)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N05 compound treatment 0.447 0.193 10.35 10.3462 1.0 3212011 TimTec1_005923 O=C(NCCOc1ccccc1)/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N06 compound treatment 0.255 5.31E-4 0.03 0.0285 1.0 3212012 TimTec1_005924 CCOC(=O)c1cn(nc1N)C2CC(=O)C3OCC2O3.CCOC(=O)c1cn(nc1N)C2CC(O)(O)C3OCC2O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N07 compound treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 3088126 TimTec1_005925 NC[C@@H]1CCCN2CCCC[C@H]12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N08 compound treatment 0.244 -0.0105 -0.56 -0.5626 -1.0 1354761 TimTec1_005926 CCC(C)NCc1ccc(o1)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N09 compound treatment 0.316 0.0615 3.31 3.3066 1.0 1518220 TimTec1_005927 CSC1=NC(=C(C(=O)Nc2ccccc2)C3(CCCCC3)C1C(=O)N)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N10 compound treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 3212013 TimTec1_005928 OC1(O)CC(C2COC1O2)n3nc(c4ccco4)n(CC=C)c3=S.C=CCn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N11 compound treatment 0.268 0.0135 0.73 0.7271 1.0 3088130 TimTec1_005929 Cc1cc2CC(C)(C)N/C(=C/C(=O)N)/c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N12 compound treatment 0.49 0.236 12.66 12.657 1.0 1138138 TimTec1_005930 CCOC(=O)c1[nH]c(C)c(CNc2ccccc2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N13 compound treatment 0.311 0.0565 3.04 3.0379 1.0 1675612 TimTec1_005931 COc1nonc1n2nnc(C(=O)c3ccccc3)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N14 compound treatment 0.367 0.113 6.05 6.0472 1.0 1140939 TimTec1_005932 CCCc1c(C)[nH]c2nc3ccccc3n2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N15 compound treatment 0.289 0.0345 1.86 1.8556 1.0 3088132 TimTec1_005933 Clc1ccccc1c2nnc3cccc(Cl)n23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N16 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1219341 TimTec1_005934 CCN(C(=O)c1c(C)c(Cl)c(C)nc1Oc2ccc(F)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N17 compound treatment 0.261 0.00653 0.35 0.351 1.0 1518508 TimTec1_005935 CC(=O)N(CC1(CC2CC3CC(C2)C1)C3)C4CC(=O)N(C4=O)c5cccc(Cl)c5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N18 compound treatment 0.243 -0.0115 -0.62 -0.6163 -1.0 3088204 TimTec1_005936 Cn1nc(cc1Cl)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N19 compound treatment 0.391 0.137 7.34 7.3369 1.0 3088206 TimTec1_005937 Cc1ccc(N/C(=C/C(=O)c2ccccc2)/C(=O)O)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N20 compound treatment 0.354 0.0995 5.35 5.3486 1.0 3088207 TimTec1_005938 CC(C)(C)C1(C)OC(=O)C(=Cc2ccc(Br)o2)C(=O)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N21 compound treatment 0.256 0.00153 0.08 0.0823 1.0 3212014 TimTec1_005939 COCCN1C=C(C(C(=C1)C(=O)OC)c2cccs2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N22 compound treatment 0.499 0.245 13.14 13.1406 1.0 3212015 TimTec1_005940 CN/1CCC\C1=C\C=C\2/SC(=S)NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N23 mock treatment 0.25 -0.00447 -0.24 -0.2401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 N24 mock treatment 0.245 -0.00947 -0.51 -0.5088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O01 compound treatment 0.274 0.0195 1.05 1.0496 1.0 1199249 TimTec1_005941 CCCn1c2ccccc2c3nnc(SCC(=O)NC(C)c4ccccc4)nc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O02 compound treatment 0.256 0.00153 0.08 0.0823 1.0 1786664 TimTec1_005942 CC(C)c1cc(=O)n2nc(N)[nH]c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O03 compound treatment 0.524 0.27 14.48 14.484 1.0 3212016 TimTec1_005943 Fc1ccccc1COc2ccccc2/C=C\3/SC(=N)NC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O04 compound treatment 0.512 0.258 13.84 13.8392 1.0 1724360 TimTec1_005944 c1c(nc2nc(c3ccccc3)c(nn12)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O05 compound treatment 0.275 0.0205 1.1 1.1033 1.0 3088212 TimTec1_005945 O=C(CSC1=NC(CC(=O)N1)c2ccccc2)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O06 compound treatment 0.298 0.0435 2.34 2.3393 1.0 1025381 TimTec1_005946 COc1ccc2CC3N(CCc4cc5OCOc5cc34)Cc2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O07 compound treatment 0.239 -0.0155 -0.83 -0.8313 -1.0 1512733 TimTec1_005947 COc1ccc(cc1)C2=C(C)C(c3cccs3)c4ccccc4O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O08 compound treatment 0.265 0.0105 0.57 0.5659 1.0 3088214 TimTec1_005948 COC(=O)c1ccc(cc1)C2OCCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O09 compound treatment 0.331 0.0765 4.11 4.1126 1.0 3212017 TimTec1_005949 CCN(CC)N=Nc1n[nH]c2nc(C)cc(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O10 compound treatment 0.366 0.112 5.99 5.9935 1.0 1112286 TimTec1_005950 CC(=O)Nc1ccc(Cl)cc1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O11 compound treatment 0.526 0.272 14.59 14.5915 1.0 3212018 TimTec1_005951 C1C(=CC(=NN=C1c2ccccc2)c3ccccc3)c4c[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O12 compound treatment 0.277 0.0225 1.21 1.2108 1.0 3212019 TimTec1_005952 COc1cc(OC)c(/C=C/2\C(=O)NC(=O)N(C3CCCCC3)C2=O)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O13 compound treatment 0.274 0.0195 1.05 1.0496 1.0 1583863 TimTec1_005953 CCOC(=O)C1(CCN(Cc2cccc(c2)C(=O)O)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O14 compound treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 3212020 TimTec1_005954 COC(=O)c1c(NC(NC(=O)C)(C(F)(F)F)C(F)(F)F)sc2CN(C)CCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O15 compound treatment 0.337 0.0825 4.44 4.4351 1.0 1330742 TimTec1_005955 COc1ccc(cc1)C(=O)c2sc3nc(cc(c4cccs4)c3c2N)c5cccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O16 compound treatment 0.409 0.155 8.3 8.3042 1.0 1008206 TimTec1_005956 NNc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O17 compound treatment 0.312 0.0575 3.09 3.0916 1.0 3212021 TimTec1_005957 C/N=C\1/S/C(=C\c2sccc2C)/C(=O)N1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O18 compound treatment 0.259 0.00453 0.24 0.2435 1.0 1627835 TimTec1_005958 OC(C(=O)NN1CCCCC1)(c2ccsc2)c3ccsc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O19 compound treatment 0.224 -0.0305 -1.64 -1.6373 -1.0 3088220 TimTec1_005959 C/C(=N/O)/C1CCCCCCCCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O20 compound treatment 0.266 0.0115 0.62 0.6197 1.0 3212022 TimTec1_005960 Fc1cccc(C(=O)N2CCCCC2)c1F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O21 compound treatment 0.268 0.0135 0.73 0.7271 1.0 1373583 TimTec1_005961 Clc1ccc(cc1)C2(CC(=O)N3CCCCC3)C(=O)c4ccccc4C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O22 compound treatment 0.257 0.00253 0.14 0.136 1.0 1018702 TimTec1_005962 Oc1ccccc1C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O23 mock treatment 0.259 0.00453 0.24 0.2435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 O24 mock treatment 0.256 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P01 compound treatment 0.252 -0.00247 -0.13 -0.1327 -1.0 1707498 TimTec1_005963 COc1ccc(C(=O)c2ccccc2)c(OCC(=O)NC3(CC4CC5CC(C4)C3)C5)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P02 compound treatment 0.235 -0.0195 -1.05 -1.0462 -1.0 3088297 TimTec1_005964 CC1(C)COP(=S)(OC1)N(C2=NCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P03 compound treatment 0.243 -0.0115 -0.62 -0.6163 -1.0 3212023 TimTec1_005965 CCC1CC(O)C(C)C(C)S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P04 compound treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 3088299 TimTec1_005966 Oc1c(Cl)cc(Cl)cc1C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P05 compound treatment 0.451 0.197 10.56 10.5612 1.0 1497087 TimTec1_005967 COc1ccccc1n2c(CSc3ccccn3)nc4ccccc4c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P06 compound treatment 0.353 0.0985 5.29 5.2949 1.0 3088301 TimTec1_005968 FC(F)(F)c1ccc(cc1)C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P07 compound treatment 0.423 0.169 9.06 9.0565 1.0 3212024 TimTec1_005969 Brc1cccc(CSCC(=O)Nc2ccc3ccccc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P08 compound treatment 0.229 -0.0255 -1.37 -1.3686 -1.0 3212086 TimTec1_005970 Cc1cc(Cl)ccc1OC2C(N(C2=O)c3cccc(c3)C(F)(F)F)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P09 compound treatment 0.246 -0.00847 -0.46 -0.4551 -1.0 1275002 TimTec1_005971 CC(NC(=O)NC1(CC1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P10 compound treatment 0.241 -0.0135 -0.72 -0.7238 -1.0 1579554 TimTec1_005972 COc1ccc(cc1OC)C2SCC(=O)N2CCN3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P11 compound treatment 0.274 0.0195 1.05 1.0496 1.0 3088305 TimTec1_005973 CNc1nc(cc(n1)C(F)(F)F)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P12 compound treatment 0.393 0.139 7.44 7.4444 1.0 1420064 TimTec1_005974 Fc1ccccc1c2nnn(CC(=O)NCc3ccc4OCOc4c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P13 compound treatment 0.27 0.0155 0.83 0.8346 1.0 1669226 TimTec1_005975 CCOC(=O)C1=C(N)CC(NC1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P14 compound treatment 0.271 0.0165 0.89 0.8884 1.0 3088307 TimTec1_005976 COc1cc(ccc1n2cnnn2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P15 compound treatment 0.261 0.00653 0.35 0.351 1.0 1638981 TimTec1_005977 COc1ccc(NC(=O)C2(CCCCC2)N(C(=O)Cn3nnnc3N)c4ccc(OC)cc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P16 compound treatment 0.257 0.00253 0.14 0.136 1.0 1387660 TimTec1_005978 CN(C)c1ccc(cc1)C(N2C(CC2=O)c3ccco3)C(=O)Nc4c(C)cccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P17 compound treatment 0.268 0.0135 0.73 0.7271 1.0 1166206 TimTec1_005979 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)N(CC=C)CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P18 compound treatment 0.278 0.0235 1.26 1.2645 1.0 3088310 TimTec1_005980 Cc1ccccc1CSc2nnc3c4ccccc4n(CC=C)c3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P19 compound treatment 0.249 -0.00547 -0.29 -0.2939 -1.0 3212087 TimTec1_005981 CC(=O)NC(NCC1(CC2CC3CC(C2)C1)C3)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P20 compound treatment 0.248 -0.00647 -0.35 -0.3476 -1.0 3212088 TimTec1_005982 Brc1ccc2nc(oc(=O)c2c1)c3ccc4C(=O)N(C5CCCCC5)C(=O)c4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P21 compound treatment 0.478 0.224 12.01 12.0121 1.0 1700737 TimTec1_005983 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(Nc4ccccc4)c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P22 compound treatment 0.327 0.0725 3.9 3.8977 1.0 3212089 TimTec1_005984 CN1CCC(CC1)OC(=O)c2cc3cc(Br)ccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P23 mock treatment 0.253 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2079 P24 mock treatment 0.251 -0.00347 -0.19 -0.1864 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A01 compound treatment 0.321 0.068 3.65 3.6542 1.0 1333525 TimTec1_005985 COc1ccc(cc1OC)C(=O)N2CCN(CC2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A02 compound treatment 0.47 0.217 11.66 11.6611 1.0 3088315 TimTec1_005986 Cc1n(Cc2ccccc2)c(O)cc3nn(c4nc5ccccc5s4)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A03 compound treatment 0.253 0.0 0.0 -1.0 -1.0 3088316 TimTec1_005987 CN(C)S(=O)(=O)c1cccc2N=S=Nc21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A04 compound treatment 0.355 0.102 5.48 5.4813 1.0 3088391 TimTec1_005988 COc1ccc(OC2C(N(C2=O)c3cccc(c3)C(F)(F)F)c4ccc(OC)c(OC)c4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A05 compound treatment 0.257 0.004 0.21 0.215 1.0 3212090 TimTec1_005989 O=c1n(c2ccccc2n1S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A06 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 3088394 TimTec1_005990 CCN(CC)c1nc(N)nc(n1)N(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A07 compound treatment 0.271 0.018 0.97 0.9673 1.0 3212091 TimTec1_005991 Oc1ccc(CNCC2NCCc3ccccc23)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A08 compound treatment 0.24 -0.013 -0.7 -0.6986 -1.0 1871268 TimTec1_005992 COc1cc(cc(OC)c1OC)C2Sc3ccccc3NC4=C2C(=O)OC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A09 compound treatment 0.358 0.105 5.64 5.6425 1.0 3088397 TimTec1_005993 FC(F)(F)c1ccc(cc1)C(=O)Nc2coc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A10 compound treatment 0.259 0.006 0.32 0.3224 1.0 3212092 TimTec1_005994 COc1ccccc1NC(=O)COc2nsnc2N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A11 compound treatment 0.256 0.003 0.16 0.1612 1.0 1380446 TimTec1_005995 CCc1nc2ccccc2n1C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A12 compound treatment 0.264 0.011 0.59 0.5911 1.0 3212093 TimTec1_005996 O=C(CC1N(NC(=O)c2ccncc2)C(=S)N(C1=O)c3ccccc3)NCCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A13 compound treatment 0.258 0.005 0.27 0.2687 1.0 3088399 TimTec1_005997 CC1(C)CC(CCO1)n2nc(O)cc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A14 compound treatment 0.601 0.348 18.7 18.7008 1.0 3212094 TimTec1_005998 COc1cccc(Nc2ccc(Nc3cccc(OC)c3)nn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A15 compound treatment 0.259 0.006 0.32 0.3224 1.0 3212095 TimTec1_005999 CCOc1ccccc1C2C(=CN(CC3(CC4CC5CC(C4)C3)C5)C=C2C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A16 compound treatment 0.416 0.163 8.76 8.7593 1.0 3088402 TimTec1_006000 Clc1ccc(NCc2cc3ccccc3[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A17 compound treatment 0.3 0.047 2.53 2.5257 1.0 3088404 TimTec1_006001 Clc1cccc(c1)C2NCc3ccccc3-n4cccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A18 compound treatment 0.27 0.017 0.91 0.9135 1.0 3212096 TimTec1_006002 COc1ccccc1NC(=O)Cn2nc(n(N)c2=S)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A19 compound treatment 0.295 0.042 2.26 2.257 1.0 1610618 TimTec1_006003 CN1C(=O)C(CC(=O)Nc2ccc(F)cc2)N(NC(=O)c3cccc(F)c3)C1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A20 compound treatment 0.295 0.042 2.26 2.257 1.0 3088406 TimTec1_006004 O=C1N(CCc2ccccc2)C(NCCc3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A21 compound treatment 0.282 0.029 1.56 1.5584 1.0 3212097 TimTec1_006005 CC1(C)CC(=O)C=C(C1)NCC2NCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A22 compound treatment 0.286 0.033 1.77 1.7734 1.0 1307924 TimTec1_006006 NCCOc1ccccc1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A23 mock treatment 0.276 0.023 1.24 1.236 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 A24 mock treatment 0.275 0.022 1.18 1.1822 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B01 compound treatment 0.279 0.026 1.4 1.3972 1.0 3212098 TimTec1_006007 CC(C)(C)c1ccc(cc1)C2CC(=O)c3cnc(N)nc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B02 compound treatment 0.263 0.01 0.54 0.5374 1.0 3088409 TimTec1_006008 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3cccnc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B03 compound treatment 0.355 0.102 5.48 5.4813 1.0 3212099 TimTec1_006009 Brc1cccc(c1)C(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B04 compound treatment 0.275 0.022 1.18 1.1822 1.0 3212100 TimTec1_006010 CC(=O)NC1=NN(C(=O)C)C2(S1)C(=O)N(Cc3ccccc3)c4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B05 compound treatment 0.305 0.052 2.79 2.7944 1.0 3088411 TimTec1_006011 COc1cc(OC)cc(c1)C(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B06 compound treatment 0.278 0.025 1.34 1.3434 1.0 3212101 TimTec1_006012 COC(=O)C1C(CC(=CC1=O)Nc2ccc(F)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B07 compound treatment 0.342 0.089 4.78 4.7827 1.0 3088413 TimTec1_006013 O=S(=O)(Nc1ccc2c(c1)oc3ccccc32)N4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B08 compound treatment 0.254 0.001 0.05 0.0537 1.0 3088482 TimTec1_006014 CCN1C(=O)/C(=C\2/C(=O)N3c4c2cc(OC(=O)c5cccs5)cc4C(=CC3(C)C)C)/SC1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B09 compound treatment 0.461 0.208 11.18 11.1775 1.0 3088485 TimTec1_006015 Fc1ccc(cc1)N2CCN(CC2)C(=O)CSc3nnc(c4ccco4)n3CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B10 compound treatment 0.515 0.262 14.08 14.0793 1.0 3212102 TimTec1_006016 CC1Cn2c(nnc2S1)c3cccc(O)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B11 compound treatment 0.301 0.048 2.58 2.5794 1.0 3212103 TimTec1_006017 CCCC(=O)C1=C(CC(C)(C)CC1=O)NCCc2ccc(OCC)c(OCC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B12 compound treatment 0.296 0.043 2.31 2.3107 1.0 3088487 TimTec1_006018 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4cccc(F)c4F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B13 compound treatment 0.27 0.017 0.91 0.9135 1.0 1497125 TimTec1_006019 COC(=O)Cn1c(=O)oc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B14 compound treatment 0.269 0.016 0.86 0.8598 1.0 3212104 TimTec1_006020 CCOc1ccc(CCN2C(=O)C3C4CC(C=C4)C3C2=O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B15 compound treatment 0.249 -0.004 -0.21 -0.215 -1.0 3212105 TimTec1_006021 Cn1c(=O)cc2-c3ccccc3C(=O)c4c(NS(=O)(=O)c5ccccc5)ccc1c24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B16 compound treatment 0.359 0.106 5.7 5.6962 1.0 3088490 TimTec1_006022 COc1cccc(Nc2ncccc2C(=O)Nc3ccc(F)cc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B17 compound treatment 0.323 0.07 3.76 3.7617 1.0 3212162 TimTec1_006023 Nc1nonc1c2nc3ccccc3n2CC(=O)N4CCN(CC4)c5ccc(F)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B18 compound treatment 0.272 0.019 1.02 1.021 1.0 3088492 TimTec1_006024 CC1(C)CC(=O)C(=C(C1)NCc2ccco2)C(NC(=O)c3ccncc3)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B19 compound treatment 0.299 0.046 2.47 2.4719 1.0 3212163 TimTec1_006025 Cc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)CCCN4C(=O)c5ccccc5C4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B20 compound treatment 0.557 0.304 16.34 16.3363 1.0 3088494 TimTec1_006026 Clc1ccc(cc1)c2nnc3SC(=C)Cn23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B21 compound treatment 0.513 0.26 13.97 13.9719 1.0 3212164 TimTec1_006027 CCN(Cc1ccccc1)C(=O)CSc2nc(C)c(Cl)c(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B22 compound treatment 0.273 0.02 1.07 1.0748 1.0 3088496 TimTec1_006028 Fc1ccc(cc1)S(=O)(=O)NCCN2CCNC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B23 mock treatment 0.261 0.008 0.43 0.4299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 B24 mock treatment 0.27 0.017 0.91 0.9135 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C01 compound treatment 0.263 0.01 0.54 0.5374 1.0 3212165 TimTec1_006029 Cc1ccc(cc1Cl)N2CCN(CC2)C(=O)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C02 compound treatment 0.24 -0.013 -0.7 -0.6986 -1.0 3212166 TimTec1_006030 FC(F)(F)c1ccccc1NC(=O)c2ccc(Cn3cnnn3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C03 compound treatment 0.235 -0.018 -0.97 -0.9673 -1.0 3088498 TimTec1_006031 Nc1ccccc1C(=O)Nc2cc(cc(c2)C(=O)O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C04 compound treatment 0.253 0.0 0.0 -1.0 -1.0 3212167 TimTec1_006032 CS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C05 compound treatment 0.263 0.01 0.54 0.5374 1.0 3088500 TimTec1_006033 Fc1ccccc1C2CC(=O)Nc3cc4CCCc4cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C06 compound treatment 0.238 -0.015 -0.81 -0.8061 -1.0 3212168 TimTec1_006034 Oc1ccccc1n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C07 compound treatment 0.247 -0.006 -0.32 -0.3224 -1.0 3212169 TimTec1_006035 Fc1cccc(F)c1CNCC2NCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C08 compound treatment 0.268 0.015 0.81 0.8061 1.0 3088503 TimTec1_006036 CSC1=NC2(C)CCCCC2c3c1ccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C09 compound treatment 0.246 -0.007 -0.38 -0.3762 -1.0 3212170 TimTec1_006037 CC(=O)ON1C(C)(C)Cc2noc(N)c2C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C10 compound treatment 0.268 0.015 0.81 0.8061 1.0 3212171 TimTec1_006038 C(CSc1nnc2c3ccccc3nc(c4ccccc4)n12)Oc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C11 compound treatment 0.275 0.022 1.18 1.1822 1.0 1197164 TimTec1_006039 CC(C)Cc1ccc(cc1)C(C)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C12 compound treatment 0.267 0.014 0.75 0.7523 1.0 3088505 TimTec1_006040 CCOc1cc(CN)c(cc1OCC)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C13 compound treatment 0.216 -0.037 -1.99 -1.9883 -1.0 3088575 TimTec1_006041 Clc1ccc(c2ccccc12)S(=O)(=O)NCC3(CC4CC5CC(C4)C3)C5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C14 compound treatment 0.379 0.126 6.77 6.771 1.0 1249304 TimTec1_006042 Clc1ccc(NC(=O)NCCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C15 compound treatment 0.31 0.057 3.06 3.0631 1.0 3088578 TimTec1_006043 CCc1nc2c3no[n+]([O-])c3c4no[n+]([O-])c4c2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C16 compound treatment 0.246 -0.007 -0.38 -0.3762 -1.0 3212172 TimTec1_006044 CCCNC(=O)Cc1nnc[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C17 compound treatment 0.322 0.069 3.71 3.7079 1.0 3088580 TimTec1_006045 Cc1ccc(cc1)C(=O)c2nsc(Cl)c2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C18 compound treatment 0.407 0.154 8.28 8.2756 1.0 3212173 TimTec1_006046 Cn1ccnc1SCc2cc(=O)[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C19 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 3088582 TimTec1_006047 COC(=O)CC1CC(C)(C)NC(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C20 compound treatment 0.5 0.247 13.27 13.2733 1.0 1686023 TimTec1_006048 CCOC(=O)C1=C(SCC)c2ccc(c3ccccc3)n2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C21 compound treatment 0.267 0.014 0.75 0.7523 1.0 3212174 TimTec1_006049 O=C1CC(CC(=O)C1=CNCC2NCCc3ccccc23)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C22 compound treatment 0.285 0.032 1.72 1.7196 1.0 1535965 TimTec1_006050 Brc1ccc(cc1)S(=O)(=O)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C23 mock treatment 0.26 0.007 0.38 0.3762 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 C24 mock treatment 0.261 0.008 0.43 0.4299 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D01 compound treatment 0.367 0.114 6.13 6.1261 1.0 3088585 TimTec1_006051 C/C(=N\S(=O)(=O)c1ccc(C)cc1)/Nc2ccc(O)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D02 compound treatment 0.252 -0.001 -0.05 -0.0537 -1.0 3212175 TimTec1_006052 Cn1c(SCSc2nc3n(C)c(=O)n(C)c(=O)c3n2C)nc4n(C)c(=O)n(C)c(=O)c14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D03 compound treatment 0.3 0.047 2.53 2.5257 1.0 3088587 TimTec1_006053 Cc1ccc(OCc2ccccc2C(=O)Nc3nccs3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D04 compound treatment 0.3 0.047 2.53 2.5257 1.0 3212176 TimTec1_006054 O=C1N2C(N(Cc3ccccc3)S(=O)(=O)c4ccccc24)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D05 compound treatment 0.364 0.111 5.96 5.9649 1.0 3088589 TimTec1_006055 Brc1cncc(c1)C(=O)NCCOc2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D06 compound treatment 0.287 0.034 1.83 1.8271 1.0 3212177 TimTec1_006056 COC(=O)C1C(CC(=CC1=O)Nc2cc(OC)ccc2OC)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D07 compound treatment 0.501 0.248 13.33 13.327 1.0 3212178 TimTec1_006057 CS(=O)(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc3ccc4C(=O)OCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D08 compound treatment 0.248 -0.005 -0.27 -0.2687 -1.0 3088591 TimTec1_006058 Cc1ccccc1NC(=O)C2C3N4C(=O)CSC4=NC2(C)Oc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D09 compound treatment 0.474 0.221 11.88 11.8761 1.0 3212179 TimTec1_006059 CC(=C1C(=O)CC(CC1=O)c2ccccc2)NCCc3c(C)[nH]c4ccc(OC(F)(F)F)cc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D10 compound treatment 0.412 0.159 8.54 8.5443 1.0 3212180 TimTec1_006060 OCCCn1c(cn2c(c(nc12)c3ccccc3)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D11 compound treatment 0.302 0.049 2.63 2.6332 1.0 1303635 TimTec1_006061 S=C(NCc1ccccc1)N2CCN(Cc3ccc4OCOc4c3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D12 compound treatment 0.254 0.001 0.05 0.0537 1.0 3212181 TimTec1_006062 CCOc1cc2CNC(C3CCCCC3)c4cccn4-c2cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D13 compound treatment 0.315 0.062 3.33 3.3318 1.0 3088595 TimTec1_006063 COc1ccc(cc1)C(=O)N(CC(=O)Nc2nn(nc2C(=O)N)c3ccccc3)Cc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D14 compound treatment 0.262 0.009 0.48 0.4836 1.0 3212182 TimTec1_006064 CC(C1CC(=O)N(C1=O)c2ccc(OC(F)(F)F)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D15 compound treatment 0.283 0.03 1.61 1.6121 1.0 3212183 TimTec1_006065 COc1nc(NCCC2=CCCCC2)nc(n1)N3CC4CC(C3)c5cccc(=O)n5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D16 compound treatment 0.45 0.197 10.59 10.5864 1.0 3087442 TimTec1_006066 Oc1cccc(/C=N/N2CCCCC2)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D17 compound treatment 0.314 0.061 3.28 3.278 1.0 3212184 TimTec1_006067 CC1=C(C(c2ccc(C)o2)n3c(N1)nc4ccccc34)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D18 compound treatment 0.262 0.009 0.48 0.4836 1.0 1863683 TimTec1_006068 COc1cccc(CNC2(CC3CC4CC(C3)C2)C4)c1OCc5ccccc5F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D19 compound treatment 0.315 0.062 3.33 3.3318 1.0 3212185 TimTec1_006069 COc1ccc(cc1)C2C3C(SC(=C2C#N)N)C(=O)N(C3=O)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D20 compound treatment 0.346 0.093 5.0 4.9976 1.0 3087446 TimTec1_006070 Clc1ccc(CN2COc3ccc(Cl)cc3C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D21 compound treatment 0.257 0.004 0.21 0.215 1.0 3212186 TimTec1_006071 CN(C(=O)CSc1nc(C)c(C)c(C)c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D22 compound treatment 0.352 0.099 5.32 5.3201 1.0 1200722 TimTec1_006072 O=C1NCCN1CCNS(=O)(=O)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D23 mock treatment 0.246 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 D24 mock treatment 0.248 -0.005 -0.27 -0.2687 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E01 compound treatment 0.522 0.269 14.46 14.4555 1.0 1327534 TimTec1_006073 CCNc1nc(NCC)n2c(SCC(=O)N(c3ccccc3)c4ccccc4)nnc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E02 compound treatment 0.252 -0.001 -0.05 -0.0537 -1.0 3212187 TimTec1_006074 O=C(NCCc1ccncc1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E03 compound treatment 0.247 -0.006 -0.32 -0.3224 -1.0 3087449 TimTec1_006075 CCCn1ncc(C(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E04 compound treatment 0.452 0.199 10.69 10.6938 1.0 3212246 TimTec1_006076 O=C(CSc1nnc2sc3ccccc3n12)N4CCc5ccccc5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E05 compound treatment 0.259 0.006 0.32 0.3224 1.0 3087451 TimTec1_006077 Cc1ccc(cc1)N2COc3ccc(Cl)cc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E06 compound treatment 0.406 0.153 8.22 8.2219 1.0 3212247 TimTec1_006078 NC1=C(C#N)C(C2=C(O1)c3ccccc3CC2)c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E07 compound treatment 0.257 0.004 0.21 0.215 1.0 3087453 TimTec1_006079 FC(F)(F)c1ccccc1CNCC2NCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E08 compound treatment 0.309 0.056 3.01 3.0093 1.0 3212248 TimTec1_006080 Cc1ccc(OCCNC(=O)c2ccccc2N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E09 compound treatment 0.276 0.023 1.24 1.236 1.0 3087455 TimTec1_006081 Cc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccccc3C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E10 compound treatment 0.269 0.016 0.86 0.8598 1.0 3212249 TimTec1_006082 CC(=O)N1CCc2ccccc2C1CNC3=CC(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E11 compound treatment 0.281 0.028 1.5 1.5047 1.0 3087457 TimTec1_006083 COC(=O)c1sc(OC)c(c1O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E12 compound treatment 0.257 0.004 0.21 0.215 1.0 3212250 TimTec1_006084 Cc1[nH]c2ccccc2c1CCNC3=CC(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E13 compound treatment 0.271 0.018 0.97 0.9673 1.0 3087459 TimTec1_006085 Cc1cc(C)c2c(O)nn(C3CCCC3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E14 compound treatment 0.254 0.001 0.05 0.0537 1.0 3212251 TimTec1_006086 NC(=O)CCN1CCn2c1nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E15 compound treatment 0.381 0.128 6.88 6.8785 1.0 3212252 TimTec1_006087 Cc1ccc(C)c(c1)N/2C(=O)CS\C2=C(\C#N)/S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E16 compound treatment 0.34 0.087 4.68 4.6752 1.0 1724768 TimTec1_006088 CCCn1c(nc2ccccc12)c3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E17 compound treatment 0.254 0.001 0.05 0.0537 1.0 1293720 TimTec1_006089 CCc1ccccc1NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E18 compound treatment 0.255 0.002 0.11 0.1075 1.0 3212253 TimTec1_006090 CC(C)CC1(NC(C2C1C(=O)N(C(C)C)C2=O)c3ccccc3O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E19 compound treatment 0.272 0.019 1.02 1.021 1.0 3087463 TimTec1_006091 Clc1cccc(c1)C(=O)N2CCNC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E20 compound treatment 0.548 0.295 15.85 15.8527 1.0 3087465 TimTec1_006092 O=C1C(=C(N2CCCCC2)c3cc4CCCCc4n13)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E21 compound treatment 0.273 0.02 1.07 1.0748 1.0 3087466 TimTec1_006093 COC(=O)c1cc(=O)nc2sc3ccccc3n12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E22 compound treatment 0.527 0.274 14.72 14.7242 1.0 1602387 TimTec1_006094 OC(=O)c1cccc(c1)S(=O)(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E23 mock treatment 0.249 -0.004 -0.21 -0.215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 E24 mock treatment 0.258 0.005 0.27 0.2687 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F01 compound treatment 0.259 0.006 0.32 0.3224 1.0 1511411 TimTec1_006095 Cc1ccc2oc(=O)c(CCC(=O)O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F02 compound treatment 0.309 0.056 3.01 3.0093 1.0 3087806 TimTec1_006096 CC(=O)Nc1nonc1c2nc3ccccc3n2Cc4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F03 compound treatment 0.257 0.004 0.21 0.215 1.0 3212254 TimTec1_006097 OCCNC(=O)c1cccc(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F04 compound treatment 0.362 0.109 5.86 5.8574 1.0 3212255 TimTec1_006098 Fc1ccccc1Cn2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F05 compound treatment 0.275 0.022 1.18 1.1822 1.0 3087807 TimTec1_006099 COc1ccccc1NC(=O)c2ccccc2NS(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F06 compound treatment 0.311 0.058 3.12 3.1168 1.0 3212256 TimTec1_006100 CCOC(=O)C1C(CC(=CC1=O)Nc2ccc(cc2)C(F)(F)F)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F07 compound treatment 0.245 -0.008 -0.43 -0.4299 -1.0 3212257 TimTec1_006101 O=C(N1CCc2ccccc2C1)c3ccccc3C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F08 compound treatment 0.271 0.018 0.97 0.9673 1.0 3212258 TimTec1_006102 CC12CCC3C(CCC4CCCCC43C)C2C/C(=C\c5ccc[nH]5)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F09 compound treatment 0.271 0.018 0.97 0.9673 1.0 3087808 TimTec1_006103 CCc1c2C(=O)CCCc2nn1c3cc(Cl)ccc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F10 compound treatment 0.273 0.02 1.07 1.0748 1.0 3087809 TimTec1_006104 C/C=C/C1OC23CCCCC3C(C#N)(C(=N)O2)C1(C#N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F11 compound treatment 0.273 0.02 1.07 1.0748 1.0 3212259 TimTec1_006105 FC(F)(F)c1nnc2ccc(nn12)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F12 compound treatment 0.255 0.002 0.11 0.1075 1.0 3087810 TimTec1_006106 COC(=O)CC1=NN(C(=O)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F13 compound treatment 0.267 0.014 0.75 0.7523 1.0 3212260 TimTec1_006107 COC(=O)C1C(=CN(CCc2ccccc2)C=C1C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F14 compound treatment 0.235 -0.018 -0.97 -0.9673 -1.0 3212261 TimTec1_006108 Clc1cccc(NC(=S)NC2(CC3CC4CC(C3)C2)C4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F15 compound treatment 0.288 0.035 1.88 1.8808 1.0 3212262 TimTec1_006109 COc1ccc(CCNc2nc(Cl)nc(n2)N3CC4CC(C3)c5cccc(=O)n5C4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F16 compound treatment 0.268 0.015 0.81 0.8061 1.0 3087811 TimTec1_006110 CC1CCCCN1C(=S)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F17 compound treatment 0.268 0.015 0.81 0.8061 1.0 3087812 TimTec1_006111 CC(=O)Oc1cc(OC(=O)C)c(cc1Cl)C2(C)CC(C)(C)c3cc(Cl)c(OC(=O)C)cc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F18 compound treatment 0.259 0.006 0.32 0.3224 1.0 3212263 TimTec1_006112 COc1cccc(c1)C2C(=C(C)Nc3nc4ccccc4n23)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F19 compound treatment 0.249 -0.004 -0.21 -0.215 -1.0 3212264 TimTec1_006113 FC(F)(F)COC(=O)C1CCCCC1C(=O)NCC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F20 compound treatment 0.289 0.036 1.93 1.9346 1.0 3087813 TimTec1_006114 Clc1ccc(CCN2COc3ccc(Cl)cc3C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F21 compound treatment 0.27 0.017 0.91 0.9135 1.0 3087814 TimTec1_006115 CCCN(CCC)S(=O)(=O)c1ccc(OC)c2ncccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F22 compound treatment 0.314 0.061 3.28 3.278 1.0 3212265 TimTec1_006116 CCOC(=O)c1nnn(c1C)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F23 mock treatment 0.234 -0.019 -1.02 -1.021 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 F24 mock treatment 0.249 -0.004 -0.21 -0.215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G01 compound treatment 0.245 -0.008 -0.43 -0.4299 -1.0 1567525 TimTec1_006117 Ic1ccc(cc1)N(Cc2nnc3CCCCCn23)C(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G02 compound treatment 0.51 0.257 13.81 13.8106 1.0 3087815 TimTec1_006118 Fc1ccccc1C(=O)N2C=Cc3ccccc3C2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G03 compound treatment 0.485 0.232 12.47 12.4672 1.0 3212266 TimTec1_006119 Cc1[nH]c2ccccc2c1CCNC(=O)NC(=O)c3ccc(cc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G04 compound treatment 0.247 -0.006 -0.32 -0.3224 -1.0 3087816 TimTec1_006120 CCOC(=O)c1oc2ccc(Cl)cc2c1NC(=O)CCCN3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G05 compound treatment 0.275 0.022 1.18 1.1822 1.0 3212267 TimTec1_006121 COCc1cc(C)nc2sc(C(=O)OC)c(n3cccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G06 compound treatment 0.327 0.074 3.98 3.9766 1.0 3212268 TimTec1_006122 Cc1cnc-2c(c1)/C(=N\c3ccccc3)/c4ccccc42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G07 compound treatment 0.399 0.146 7.85 7.8457 1.0 3087817 TimTec1_006123 CN(C)S(=O)(=O)c1cc(C(=O)NCCc2c(C)n(C)c3ccccc23)c(Cl)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G08 compound treatment 0.247 -0.006 -0.32 -0.3224 -1.0 3212269 TimTec1_006124 CC(=O)N1C(CC(=O)C(C1c2ccccc2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G09 compound treatment 0.289 0.036 1.93 1.9346 1.0 3212270 TimTec1_006125 C(c1ccccc1)n2ncc3c4nc(nn4cnc23)c5ccncc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G10 compound treatment 0.275 0.022 1.18 1.1822 1.0 3087818 TimTec1_006126 COc1ccc(cc1)C(=O)c2coc3ccc(O)c(CN4CCCC4)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G11 compound treatment 0.269 0.016 0.86 0.8598 1.0 3212271 TimTec1_006127 CC1(C)Cc2ccccc2C(=N1)c3sc4nc(cc(c4c3N)C(F)(F)F)c5cccs5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G12 compound treatment 0.311 0.058 3.12 3.1168 1.0 3087819 TimTec1_006128 CCOC(=O)C1(C2C1(C)C(=O)c3ccc(Br)cc3)C(=O)OC2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G13 compound treatment 0.243 -0.01 -0.54 -0.5374 -1.0 3212272 TimTec1_006129 CC(C)n1nc(O)c2c(C)cc(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G14 compound treatment 0.298 0.045 2.42 2.4182 1.0 3087821 TimTec1_006130 C1COc2cc(/N=C/3\CCCCCN3)ccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G15 compound treatment 0.409 0.156 8.38 8.3831 1.0 3212330 TimTec1_006131 CCN1C(=C(C(=O)OC)/C(=C/c2ccc(OC)cc2)/C1=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G16 compound treatment 0.277 0.024 1.29 1.2897 1.0 3212331 TimTec1_006132 CCOc1nc(NC(=O)NS(=O)(=O)c2cccc(Cl)c2)nc(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G17 compound treatment 0.27 0.017 0.91 0.9135 1.0 1578073 TimTec1_006133 Cn1c(SCc2ccc(F)cc2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G18 compound treatment 0.26 0.007 0.38 0.3762 1.0 3212332 TimTec1_006134 FC(F)(F)COC(=O)C1CCCCC1C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G19 compound treatment 0.272 0.019 1.02 1.021 1.0 3087826 TimTec1_006135 COc1cccc(c1)C(=O)NN2C(CC(=O)N)C(=O)N(C2=S)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G20 compound treatment 0.258 0.005 0.27 0.2687 1.0 3212333 TimTec1_006136 COC(=O)C1CCCNC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G21 compound treatment 0.302 0.049 2.63 2.6332 1.0 3212334 TimTec1_006137 CCc1ccc(cc1)C2NCc3ccccc3-n4cccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G22 compound treatment 0.264 0.011 0.59 0.5911 1.0 3087829 TimTec1_006138 CCOC(=O)C1CC(=NO1)CC2OCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G23 mock treatment 0.263 0.01 0.54 0.5374 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 G24 mock treatment 0.249 -0.004 -0.21 -0.215 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H01 compound treatment 0.332 0.079 4.25 4.2453 1.0 3212335 TimTec1_006139 CCC(=O)C1=C(CCCC1=O)NCCc2c(C)[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H02 compound treatment 0.278 0.025 1.34 1.3434 1.0 3087831 TimTec1_006140 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCN(CC3)C(=S)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H03 compound treatment 0.262 0.009 0.48 0.4836 1.0 3212336 TimTec1_006141 Clc1ccc(cc1Cl)S(=O)(=O)N2CCCC2C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H04 compound treatment 0.295 0.042 2.26 2.257 1.0 3087877 TimTec1_006142 CN(c1ccccc1)c2nc(nc(n2)n3ccnc3)n4ccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H05 compound treatment 0.511 0.258 13.86 13.8644 1.0 3087880 TimTec1_006143 COC(=O)/C=C/CSc1nnc(o1)c2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H06 compound treatment 0.435 0.182 9.78 9.7803 1.0 3212337 TimTec1_006144 CCOC(=O)C1C(CC(=CC1=O)Nc2sc3CCCCc3c2C#N)c4cccc(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H07 compound treatment 0.503 0.25 13.43 13.4345 1.0 3087882 TimTec1_006145 CCc1ccc(OCC(=O)Nc2ccc3C(=O)OCc3c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H08 compound treatment 0.387 0.134 7.2 7.2009 1.0 3212338 TimTec1_006146 Cc1nc2ccccc2nc1CSc3nnc(Cc4ccccc4)n3c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H09 compound treatment 0.309 0.056 3.01 3.0093 1.0 3087884 TimTec1_006147 CCCCc1c2C(=O)CC(Cc2nn1c3ccccc3F)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H10 compound treatment 0.257 0.004 0.21 0.215 1.0 3212339 TimTec1_006148 COC1OC2COC(C2O)C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H11 compound treatment 0.263 0.01 0.54 0.5374 1.0 1214251 TimTec1_006149 CC(O)Cn1c(O)cc(C)c(C#N)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H12 compound treatment 0.328 0.075 4.03 4.0303 1.0 3212340 TimTec1_006150 Oc1ccccc1N2CCN(CC2)C(=S)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H13 compound treatment 0.242 -0.011 -0.59 -0.5911 -1.0 3212341 TimTec1_006151 CCN(CC)C(=O)NC(=O)c1c(C)cc(Cl)nc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H14 compound treatment 0.298 0.045 2.42 2.4182 1.0 1411377 TimTec1_006152 CN(C1CCCCC1)C(=S)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H15 compound treatment 0.246 -0.007 -0.38 -0.3762 -1.0 3212342 TimTec1_006153 COC(=O)C1=CN(CCOC2(CC3CC4CC(C3)C2)C4)C=C(C1c5cccc(F)c5)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H16 compound treatment 0.272 0.019 1.02 1.021 1.0 1662088 TimTec1_006154 CC1CCCCN1C(=S)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H17 compound treatment 0.303 0.05 2.69 2.6869 1.0 3212343 TimTec1_006155 Sc1nc(c(c2ccccc2)n1CC(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H18 compound treatment 0.288 0.035 1.88 1.8808 1.0 3087889 TimTec1_006156 Cc1cc2nc([nH]c2cc1C)S(=O)(=O)Cc3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H19 compound treatment 0.247 -0.006 -0.32 -0.3224 -1.0 3212344 TimTec1_006157 CCc1nc(N2CCCCC2)c3sc(=S)n(c4ccccc4)c3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H20 compound treatment 0.244 -0.009 -0.48 -0.4836 -1.0 3212345 TimTec1_006158 N#Cc1nc(nc(n1)N2CCCC2)N(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H21 compound treatment 0.265 0.012 0.64 0.6449 1.0 3087892 TimTec1_006159 CN(C)c1nc(Oc2ccc(O)nn2)nc(n1)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H22 compound treatment 0.269 0.016 0.86 0.8598 1.0 3212346 TimTec1_006160 CCOc1ccc(CC(=C2C(=O)CC(C)(C)CC2=O)Nc3ccccc3O)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H23 mock treatment 0.246 -0.007 -0.38 -0.3762 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 H24 mock treatment 0.241 -0.012 -0.64 -0.6449 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I01 compound treatment 0.224 -0.029 -1.56 -1.5584 -1.0 1646660 TimTec1_006161 CC1(C)CC(CC(C)(C)N1)NC(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I02 compound treatment 0.479 0.226 12.14 12.1448 1.0 3212347 TimTec1_006162 CCOC(=O)C1CCCc2c1[nH]c3ccc(cc23)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I03 compound treatment 0.259 0.006 0.32 0.3224 1.0 3212348 TimTec1_006163 CCCS(=O)(=O)c1c(C(=O)c2ccc(F)cc2)n3ccc(CC)cc3c1S(=O)(=O)CCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I04 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 1516298 TimTec1_006164 CCOC(=O)c1c(CC(C#N)(c2ccccc2)c3ccccc3)oc4ccc(OC)cc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I05 compound treatment 0.301 0.048 2.58 2.5794 1.0 3212349 TimTec1_006165 Cc1cc(C)c2c(c(sc2n1)C(=O)Oc3ccccc3)n4cccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I06 compound treatment 0.263 0.01 0.54 0.5374 1.0 3087896 TimTec1_006166 Cc1ccc(cc1)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I07 compound treatment 0.241 -0.012 -0.64 -0.6449 -1.0 3087898 TimTec1_006167 CN(C1CCN(C)CC1)C(=O)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I08 compound treatment 0.463 0.21 11.28 11.285 1.0 1801410 TimTec1_006168 CCC(Sc1ncccn1)C(=O)Nc2cc(C)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I09 compound treatment 0.296 0.043 2.31 2.3107 1.0 3087935 TimTec1_006169 FC(F)(F)c1nc2sc3ccccc3n2c(=N)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I10 compound treatment 0.256 0.003 0.16 0.1612 1.0 3087938 TimTec1_006170 Cc1nc(Cl)c2sc(=S)n(c3ccccc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I11 compound treatment 0.285 0.032 1.72 1.7196 1.0 3212350 TimTec1_006171 Cc1cc(NC(=O)C2CC(=O)OC2c3ccccc3)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I12 compound treatment 0.248 -0.005 -0.27 -0.2687 -1.0 3212351 TimTec1_006172 CC1(C)CC(=O)c2cnc(NC3OC(=O)c4ccccc34)nc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I13 compound treatment 0.348 0.095 5.11 5.1051 1.0 1875964 TimTec1_006173 CSc1nc2n(ncc2c(=O)n1N)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I14 compound treatment 0.354 0.101 5.43 5.4275 1.0 3212352 TimTec1_006174 Fc1ccccc1N2CCN(CC2)C(=O)c3cc4cccc(CC=C)c4oc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I15 compound treatment 0.244 -0.009 -0.48 -0.4836 -1.0 3087941 TimTec1_006175 COc1ccc(cc1OC)C2NCC3(C)CN2CC(C)C3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I16 compound treatment 0.261 0.008 0.43 0.4299 1.0 3212353 TimTec1_006176 COc1ccc(OC)c2C(=O)NC(C)(C)Cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I17 compound treatment 0.27 0.017 0.91 0.9135 1.0 3087943 TimTec1_006177 Cc1nc(c(C)s1)c2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I18 compound treatment 0.249 -0.004 -0.21 -0.215 -1.0 1418925 TimTec1_006178 Cc1c(C#N)c(=O)n(nc1C(=O)NN)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I19 compound treatment 0.258 0.005 0.27 0.2687 1.0 3087945 TimTec1_006179 CCOc1cc(NC(=O)c2ccc(OC)cc2)c(C#N)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I20 compound treatment 0.263 0.01 0.54 0.5374 1.0 3212354 TimTec1_006180 OC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)C3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I21 compound treatment 0.281 0.028 1.5 1.5047 1.0 3212355 TimTec1_006181 CCOC(=O)c1c(C)nc2-c3ccccc3C(=O)c2c1c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I22 compound treatment 0.274 0.021 1.13 1.1285 1.0 3087948 TimTec1_006182 Cc1nn(C(=O)c2ccc(cc2)C(C)(C)C)c(N)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I23 mock treatment 0.257 0.004 0.21 0.215 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 I24 mock treatment 0.252 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J01 compound treatment 0.458 0.205 11.02 11.0163 1.0 3212356 TimTec1_006183 O=c1[nH]c2ccc(cc2s1)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J02 compound treatment 0.475 0.222 11.93 11.9298 1.0 3087950 TimTec1_006184 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCN(CC3)C(=S)NC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J03 compound treatment 0.248 -0.005 -0.27 -0.2687 -1.0 3212357 TimTec1_006185 Nn1c(S)nnc1C(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J04 compound treatment 0.261 0.008 0.43 0.4299 1.0 3212416 TimTec1_006186 Cc1ccc(NC(=O)NC(NC(=O)Cc2ccccc2)(C(F)(F)F)C(F)(F)F)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J05 compound treatment 0.485 0.232 12.47 12.4672 1.0 3087952 TimTec1_006187 Cc1ccc(o1)C(=O)CSc2nnc(c3cccs3)n2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J06 compound treatment 0.28 0.027 1.45 1.4509 1.0 1171228 TimTec1_006188 CN(CCc1ccccn1)C(=S)Nc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J07 compound treatment 0.244 -0.009 -0.48 -0.4836 -1.0 3087954 TimTec1_006189 CN(C)c1ccc(cc1)C(N2CCOCC2)P(=O)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J08 compound treatment 0.282 0.029 1.56 1.5584 1.0 3212417 TimTec1_006190 CC(C)C1OC(OCC1(C)C)c2cccc(NC(=O)c3ccc(F)cc3)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J09 compound treatment 0.393 0.14 7.52 7.5233 1.0 3212418 TimTec1_006191 CCOc1ccc(CCNC2=C(C(=O)CC)C(=O)CC(C2)c3ccccc3)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J10 compound treatment 0.325 0.072 3.87 3.8691 1.0 3087957 TimTec1_006192 Cc1nc(SCC(=O)NCc2ccc(Cl)cc2)c(C#N)c(C)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J11 compound treatment 0.354 0.101 5.43 5.4275 1.0 3212419 TimTec1_006193 CCC(CC)NS(=O)(=O)c1cccc(c1)C(=O)NCCOc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J12 compound treatment 0.249 -0.004 -0.21 -0.215 -1.0 3087958 TimTec1_006194 NC(Cn1ccnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J13 compound treatment 0.257 0.004 0.21 0.215 1.0 3087960 TimTec1_006195 Cc1cc(Cl)nc(Cl)c1C(=O)NC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J14 compound treatment 0.302 0.049 2.63 2.6332 1.0 3212420 TimTec1_006196 Cc1ccc(NC(=S)Nc2ccc(cc2)N3CCOCC3)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J15 compound treatment 0.252 -0.001 -0.05 -0.0537 -1.0 3212421 TimTec1_006197 Cc1nc2cccc(C(=O)N3CCN(CC3)c4ccccc4)c2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J16 compound treatment 0.502 0.249 13.38 13.3807 1.0 3087985 TimTec1_006198 COc1ccc(OCc2nc(N)nc(Nc3ccc(C)cc3)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J17 compound treatment 0.319 0.066 3.55 3.5467 1.0 3212422 TimTec1_006199 CC(C)OC(=O)C1CC=CCC1C(=O)NCCc2c(C)[nH]c3ccc(OC(F)(F)F)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J18 compound treatment 0.254 0.001 0.05 0.0537 1.0 3087987 TimTec1_006200 Cc1cc(nn1CC(=O)Nc2ccc(CC#N)cc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J19 compound treatment 0.237 -0.016 -0.86 -0.8598 -1.0 3212423 TimTec1_006201 CCc1nc(N2CCc3ccccc23)c4sc(=S)n(c5ccccc5)c4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J20 compound treatment 0.248 -0.005 -0.27 -0.2687 -1.0 3212424 TimTec1_006202 Cc1cc(C=C2C(=O)OC(C)(OC2=O)C(C)(C)C)c(C)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J21 compound treatment 0.275 0.022 1.18 1.1822 1.0 3087990 TimTec1_006203 COc1ccc(cc1)C2(CNC(=O)c3ccco3)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J22 compound treatment 0.255 0.002 0.11 0.1075 1.0 3212425 TimTec1_006204 OC(=O)CC(C(=O)O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J23 mock treatment 0.251 -0.002 -0.11 -0.1075 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 J24 mock treatment 0.245 -0.008 -0.43 -0.4299 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K01 compound treatment 0.244 -0.009 -0.48 -0.4836 -1.0 3087991 TimTec1_006205 CC1CCc2nc(SC3CC(=O)C4OCC3O4)nc(c2C1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K02 compound treatment 0.375 0.122 6.56 6.556 1.0 3212426 TimTec1_006206 CCOC(=O)Cc1nnc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K03 compound treatment 0.257 0.004 0.21 0.215 1.0 3087993 TimTec1_006207 C=CCNC(=O)c1scc2OCCOc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K04 compound treatment 0.25 -0.003 -0.16 -0.1612 -1.0 3212427 TimTec1_006208 Brc1cccc(c1)C2CC(=O)Oc3c2c(=O)oc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K05 compound treatment 0.27 0.017 0.91 0.9135 1.0 3087996 TimTec1_006209 CC(C)COC(=O)n1n[n+]([O-])c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K06 compound treatment 0.255 0.002 0.11 0.1075 1.0 3212428 TimTec1_006210 COc1ccccc1n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K07 compound treatment 0.273 0.02 1.07 1.0748 1.0 3087998 TimTec1_006211 O=C(NCc1ccco1)c2scc3OCCOc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K08 compound treatment 0.245 -0.008 -0.43 -0.4299 -1.0 3212429 TimTec1_006212 OC(=O)CCN1C(=O)c2ccncc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K09 compound treatment 0.261 0.008 0.43 0.4299 1.0 3088000 TimTec1_006213 CC1(C)OC(C)(C)/C(=C/c2c(Cl)cccc2Cl)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K10 compound treatment 0.268 0.015 0.81 0.8061 1.0 1872861 TimTec1_006214 CC(=O)N(CCc1ccc(C)[n+]([O-])c1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K11 compound treatment 0.353 0.1 5.37 5.3738 1.0 3212430 TimTec1_006215 CN(C(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccco3)c4ccc(OC(F)(F)F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K12 compound treatment 0.284 0.031 1.67 1.6659 1.0 3088002 TimTec1_006216 OCCN1CCN(CC1)c2c(c3ccccc3)c4cc(Cl)ccc4[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K13 compound treatment 0.261 0.008 0.43 0.4299 1.0 3212431 TimTec1_006217 CC1CN(C)C(C)CC1n2nc(O)cc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K14 compound treatment 0.372 0.119 6.39 6.3948 1.0 3088004 TimTec1_006218 OC1(CCCCC1)C(=O)/C=C/c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K15 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 3212432 TimTec1_006219 CC1CCCC(C)N1C(=O)c2scc3OCCOc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K16 compound treatment 0.354 0.101 5.43 5.4275 1.0 3212433 TimTec1_006220 FC(F)(F)c1ccc(cc1)C(=O)Nc2ccccc2NC(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K17 compound treatment 0.442 0.189 10.16 10.1565 1.0 1594831 TimTec1_006221 c1[nH]c2ccccc2c1c3csc(n3)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K18 compound treatment 0.257 0.004 0.21 0.215 1.0 3212434 TimTec1_006222 CC(C)Nc1nc(nc(n1)N2CC3CC(C2)c4cccc(=O)n4C3)N5CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K19 compound treatment 0.424 0.171 9.19 9.1892 1.0 3212435 TimTec1_006223 CCOc1nc(NC(=O)NC(=O)c2cccs2)nc(n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K20 compound treatment 0.256 0.003 0.16 0.1612 1.0 3088048 TimTec1_006224 CC1C(C)C(=O)CCN1C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K21 compound treatment 0.483 0.23 12.36 12.3597 1.0 3212436 TimTec1_006225 O=C(NCCc1nc(cs1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K22 compound treatment 0.32 0.067 3.6 3.6004 1.0 3088051 TimTec1_006226 Fc1ccccc1/C=C(\C#N)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K23 mock treatment 0.255 0.002 0.11 0.1075 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 K24 mock treatment 0.255 0.002 0.11 0.1075 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L01 compound treatment 0.58 0.327 17.57 17.5723 1.0 3212437 TimTec1_006227 O=C(Nc1ccc2n(cnc2c1)C3CCCCC3)c4cc5ccccc5o4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L02 compound treatment 0.269 0.016 0.86 0.8598 1.0 3088053 TimTec1_006228 O=C1CCCN1CCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L03 compound treatment 0.297 0.044 2.36 2.3645 1.0 3212438 TimTec1_006229 Cc1cccc(NC(=O)c2ccccc2N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L04 compound treatment 0.275 0.022 1.18 1.1822 1.0 3212439 TimTec1_006230 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3cccs3)c4ccccc4C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L05 compound treatment 0.276 0.023 1.24 1.236 1.0 3088056 TimTec1_006231 Oc1ccc(cc1)c2cnc3ccncc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L06 compound treatment 0.26 0.007 0.38 0.3762 1.0 1621990 TimTec1_006232 COc1cccc(NC(=S)N(C)C2CCN(C)CC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L07 compound treatment 0.247 -0.006 -0.32 -0.3224 -1.0 3212440 TimTec1_006233 CN(c1ccccc1N(C)S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L08 compound treatment 0.324 0.071 3.82 3.8154 1.0 3212441 TimTec1_006234 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L09 compound treatment 0.258 0.005 0.27 0.2687 1.0 3088059 TimTec1_006235 Fc1ccc(cc1)N2C(=O)CC(C3=C2CCCC3=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L10 compound treatment 0.289 0.036 1.93 1.9346 1.0 3212442 TimTec1_006236 Cc1cc(Cl)nc(Cl)c1C(=O)NC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L11 compound treatment 0.304 0.051 2.74 2.7406 1.0 3088060 TimTec1_006237 CC(=O)N1CCc2[nH]c3ccc(C)cc3c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L12 compound treatment 0.291 0.038 2.04 2.042 1.0 3212739 TimTec1_006238 COc1ccc(/C=N/N2CCOCC2)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L13 compound treatment 0.488 0.235 12.63 12.6284 1.0 1849557 TimTec1_006239 Nc1c(sc2sc(C(=O)Nc3ccccc3)c(N)c12)C(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L14 compound treatment 0.252 -0.001 -0.05 -0.0537 -1.0 3088062 TimTec1_006240 CC1CCc2c(C1)sc3nc(SCc4nc5ccccc5nc4C)n(C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L15 compound treatment 0.256 0.003 0.16 0.1612 1.0 3212740 TimTec1_006241 CCC1C(N(C2=C(C(=O)CC(C)(C)C2)C1=O)c3ccc(OC)cc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L16 compound treatment 0.406 0.153 8.22 8.2219 1.0 3088064 TimTec1_006242 CC1=Nc2ccccc2N=C(NC(=O)CSC(=S)N3CCCCC3)C1c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L17 compound treatment 0.259 0.006 0.32 0.3224 1.0 3212741 TimTec1_006243 S=c1sc2c(ncnc2n1c3ccccc3)N4CCN(C/C=C/c5ccccc5)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L18 compound treatment 0.263 0.01 0.54 0.5374 1.0 3212742 TimTec1_006244 C=CCNc1nc(nc(n1)n2ccnc2)N(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L19 compound treatment 0.289 0.036 1.93 1.9346 1.0 3088067 TimTec1_006245 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L20 compound treatment 0.262 0.009 0.48 0.4836 1.0 3212743 TimTec1_006246 CCC1CCCCN1C(=S)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L21 compound treatment 0.265 0.012 0.64 0.6449 1.0 3088068 TimTec1_006247 COc1ccc(cc1)C2(CNS(=O)(=O)c3ccc(C)cc3)CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L22 compound treatment 0.252 -0.001 -0.05 -0.0537 -1.0 3212744 TimTec1_006248 COc1cc(OC)c(cc1OC)C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L23 mock treatment 0.26 0.007 0.38 0.3762 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 L24 mock treatment 0.25 -0.003 -0.16 -0.1612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M01 compound treatment 0.229 -0.024 -1.29 -1.2897 -1.0 3212745 TimTec1_006249 NC(=O)CCN1C(=O)C2C3CC(C=C3)C2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M02 compound treatment 0.264 0.011 0.59 0.5911 1.0 1680974 TimTec1_006250 OC(=O)CCc1ccc([nH]1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M03 compound treatment 0.242 -0.011 -0.59 -0.5911 -1.0 1682582 TimTec1_006251 COc1ccc(cc1OC)C2(CCCC2)C(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M04 compound treatment 0.249 -0.004 -0.21 -0.215 -1.0 1457689 TimTec1_006252 CC(=O)Nc1nonc1NC(=O)CSc2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M05 compound treatment 0.368 0.115 6.18 6.1799 1.0 1008263 TimTec1_006253 O=C(Nc1ccccc1)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M06 compound treatment 0.244 -0.009 -0.48 -0.4836 -1.0 3212746 TimTec1_006254 CCC1(CN(CC2(CC)CN(C1)C(=O)c3ccc(OC)cc3)C(=O)c4ccc(OC)cc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M07 compound treatment 0.238 -0.015 -0.81 -0.8061 -1.0 3088136 TimTec1_006255 Nc1n/c(=N\c2ccccc2)/n3c4ccccc4sc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M08 compound treatment 0.339 0.086 4.62 4.6215 1.0 1134094 TimTec1_006256 O=c1[nH]c2ccccc2n1CCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M09 compound treatment 0.274 0.021 1.13 1.1285 1.0 3088138 TimTec1_006257 NC(=O)CN(Cc1ccccc1F)S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M10 compound treatment 0.46 0.207 11.12 11.1237 1.0 3212747 TimTec1_006258 CC1(C)Cc2ccccc2C(=N1)CSc3nnc4c5ccccc5[nH]c4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M11 compound treatment 0.293 0.04 2.15 2.1495 1.0 3212748 TimTec1_006259 FC(F)(F)c1cc(nc2cc(nn12)C(=O)OCC3CCCN4CCCCC34)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M12 compound treatment 0.272 0.019 1.02 1.021 1.0 3088141 TimTec1_006260 CC1(C)CC(=O)c2c(n[nH]c2C1)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M13 compound treatment 0.286 0.033 1.77 1.7734 1.0 3212749 TimTec1_006261 COc1cc(Br)cc2cc(C(=O)N3CCN(CC3)c4cc(C)ccc4C)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M14 compound treatment 0.264 0.011 0.59 0.5911 1.0 3088143 TimTec1_006262 Clc1ccc(cc1)N2Cc3ccccc3OCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M15 compound treatment 0.302 0.049 2.63 2.6332 1.0 3212750 TimTec1_006263 Cc1cc(C)c2c(N)c(sc2n1)C3=NC(C)(C)Cc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M16 compound treatment 0.256 0.003 0.16 0.1612 1.0 3088145 TimTec1_006264 Brc1ccc(cc1)C23OC(=O)C4(CCCC4)C3OC(=O)C52CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M17 compound treatment 0.44 0.187 10.05 10.049 1.0 3212751 TimTec1_006265 Cc1cc2nc(SCCOC(=O)Nc3ccc(Cl)cc3)nc(C)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M18 compound treatment 0.284 0.031 1.67 1.6659 1.0 3088147 TimTec1_006266 Cc1ccc(cc1C)N2CCN(CC2)C(=O)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M19 compound treatment 0.26 0.007 0.38 0.3762 1.0 3212752 TimTec1_006267 O=C1CC(C2COC1O2)n3nnnc3c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M20 compound treatment 0.253 0.0 0.0 -1.0 -1.0 3212753 TimTec1_006268 Nc1ccc(cc1)C(O)C(O)CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M21 compound treatment 0.254 0.001 0.05 0.0537 1.0 3212754 TimTec1_006269 CCCCN1C(=O)C2C(NC(C)(C2C1=O)C(=O)O)c3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M22 compound treatment 0.281 0.028 1.5 1.5047 1.0 3088149 TimTec1_006270 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4cc(C)c(OC)cc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M23 mock treatment 0.248 -0.005 -0.27 -0.2687 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 M24 mock treatment 0.252 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N01 compound treatment 0.325 0.072 3.87 3.8691 1.0 3212755 TimTec1_006271 CC(C)(C)c1ccc(CNC(=O)C2CCCN2C(=O)Nc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N02 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 1352036 TimTec1_006272 CNC(=O)C1Cc2ccccc2CN1S(=O)(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N03 compound treatment 0.345 0.092 4.94 4.9439 1.0 3212756 TimTec1_006273 Clc1ccccc1CS(=O)(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N04 compound treatment 0.291 0.038 2.04 2.042 1.0 3212757 TimTec1_006274 Cc1cc(Cl)ccc1OCC(=O)NCC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N05 compound treatment 0.274 0.021 1.13 1.1285 1.0 1090623 TimTec1_006275 COC(=O)c1ccc(cc1)S(=O)(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N06 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 3088153 TimTec1_006276 CCN(C1CCCCC1)C(=S)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N07 compound treatment 0.49 0.237 12.74 12.7359 1.0 3212758 TimTec1_006277 CSc1nc2ccc(cc2s1)S(=O)(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N08 compound treatment 0.253 0.0 0.0 -1.0 -1.0 3088155 TimTec1_006278 Clc1cccc(c1)n2c(=O)n3CCCn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N09 compound treatment 0.443 0.19 10.21 10.2102 1.0 3212759 TimTec1_006279 COC(=O)c1ccc(NC(=O)CSc2nc(=O)cc(N)n2CCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N10 compound treatment 0.256 0.003 0.16 0.1612 1.0 3088223 TimTec1_006280 FC(F)(F)c1ccccc1C2NCc3ccccc3-n4cccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N11 compound treatment 0.338 0.085 4.57 4.5677 1.0 3212760 TimTec1_006281 COc1ccc(cc1OC)C2NC(=O)C(=C(S)N2c3ccccc3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N12 compound treatment 0.263 0.01 0.54 0.5374 1.0 3088227 TimTec1_006282 CCC(=O)Nc1cccc(Oc2nc(C)cc(C)c2C#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N13 compound treatment 0.269 0.016 0.86 0.8598 1.0 3212761 TimTec1_006283 FC(F)(F)C(=O)Nc1c(nnn1Cc2ccccc2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N14 compound treatment 0.249 -0.004 -0.21 -0.215 -1.0 3212762 TimTec1_006284 CN1C2=C(C(NC1=O)c3ccccc3)C(=O)N(CCc4ccccc4)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N15 compound treatment 0.266 0.013 0.7 0.6986 1.0 3088229 TimTec1_006285 COc1cc2nc(NC(=N)N)nc(O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N16 compound treatment 0.432 0.179 9.62 9.6191 1.0 3088230 TimTec1_006286 CCOC(=O)c1c(NC2=CC(=O)CCC2)sc3CCCCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N17 compound treatment 0.261 0.008 0.43 0.4299 1.0 3212763 TimTec1_006287 Brc1ccc(cc1)C2N(C(=O)C32CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N18 compound treatment 0.267 0.014 0.75 0.7523 1.0 3212827 TimTec1_006288 COc1ccc(/C=C/C(=O)C2(O)CCCCC2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N19 compound treatment 0.265 0.012 0.64 0.6449 1.0 3088233 TimTec1_006289 Fc1cnc(Nc2ccccc2)nc1N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N20 compound treatment 0.365 0.112 6.02 6.0186 1.0 3212828 TimTec1_006290 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N21 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 3088235 TimTec1_006291 COc1ccccc1NC(=O)C2CC(=O)OC32CCOC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N22 compound treatment 0.389 0.136 7.31 7.3084 1.0 3212829 TimTec1_006292 COC(=O)N1CCN(CC1)c2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N23 mock treatment 0.243 -0.01 -0.54 -0.5374 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 N24 mock treatment 0.24 -0.013 -0.7 -0.6986 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O01 compound treatment 0.233 -0.02 -1.07 -1.0748 -1.0 3212830 TimTec1_006293 CC1(C)CN2C(N(C(=S)N2C1)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O02 compound treatment 0.265 0.012 0.64 0.6449 1.0 3088238 TimTec1_006294 COC(=O)c1noc(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O03 compound treatment 0.251 -0.002 -0.11 -0.1075 -1.0 3088239 TimTec1_006295 CN(C(=O)c1nc2ncccn2n1)c3ccc(OC(F)(F)F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O04 compound treatment 0.241 -0.012 -0.64 -0.6449 -1.0 3212831 TimTec1_006296 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccc(Cl)cc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O05 compound treatment 0.365 0.112 6.02 6.0186 1.0 3212832 TimTec1_006297 COC(=O)CC/1=NN(C(=O)\C1=C(\C)/O)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O06 compound treatment 0.307 0.054 2.9 2.9018 1.0 3088242 TimTec1_006298 Sc1nnc(c2ccco2)n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O07 compound treatment 0.24 -0.013 -0.7 -0.6986 -1.0 3088243 TimTec1_006299 CC1(C)OC(=NC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O08 compound treatment 0.288 0.035 1.88 1.8808 1.0 3212833 TimTec1_006300 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3c(C)cccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O09 compound treatment 0.256 0.003 0.16 0.1612 1.0 3088245 TimTec1_006301 OC(=O)CCc1ccc(o1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O10 compound treatment 0.303 0.05 2.69 2.6869 1.0 3212834 TimTec1_006302 CC(=O)N1CCc2ccccc2C1CNC=C3C(=O)CC(CC3=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O11 compound treatment 0.262 0.009 0.48 0.4836 1.0 3088248 TimTec1_006303 C1Oc2ccc(cc2O1)C3NCc4ccccc4-n5cccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O12 compound treatment 0.286 0.033 1.77 1.7734 1.0 3212835 TimTec1_006304 CN(C)c1ccc(cc1)c2n[nH]c3CCCC(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O13 compound treatment 0.29 0.037 1.99 1.9883 1.0 3212836 TimTec1_006305 CCN(C1CCCCC1)C(=O)c2cc3cc(Br)cc(OC)c3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O14 compound treatment 0.381 0.128 6.88 6.8785 1.0 3088319 TimTec1_006306 COc1ccc(NCc2cc3ccccc3[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O15 compound treatment 0.44 0.187 10.05 10.049 1.0 3212837 TimTec1_006307 COc1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O16 compound treatment 0.266 0.013 0.7 0.6986 1.0 3088323 TimTec1_006308 S=c1n(CN2CCOCC2)nc3CCCCCn31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O17 compound treatment 0.393 0.14 7.52 7.5233 1.0 3212838 TimTec1_006309 CCCNC(=O)Nc1ccc2c(c1)oc3ccccc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O18 compound treatment 0.255 0.002 0.11 0.1075 1.0 3088325 TimTec1_006310 O=C1N(C2CCCCC2)C(=O)c3cnccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O19 compound treatment 0.292 0.039 2.1 2.0958 1.0 3212839 TimTec1_006311 C/C(=C\1/C(=NN(C1=O)c2nc3ccccc3s2)C)/NCCc4c(C)[nH]c5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O20 compound treatment 0.259 0.006 0.32 0.3224 1.0 3088326 TimTec1_006312 CN(C)C(=O)N1CCNCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O21 compound treatment 0.336 0.083 4.46 4.4602 1.0 3088328 TimTec1_006313 CC1(C)OC(C)(C)/C(=C/c2ccc3cccnc3c2)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O22 compound treatment 0.354 0.101 5.43 5.4275 1.0 3212840 TimTec1_006314 N=C1OC23CCCCC3C1(C#N)C(C#N)(C#N)C(O2)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O23 mock treatment 0.256 0.003 0.16 0.1612 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 O24 mock treatment 0.254 0.001 0.05 0.0537 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P01 compound treatment 0.476 0.223 11.98 11.9836 1.0 3088330 TimTec1_006315 CSc1nc2ccc(cc2s1)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P02 compound treatment 0.256 0.003 0.16 0.1612 1.0 1180888 TimTec1_006316 O=C(C1Cc2ccccc2CN1S(=O)(=O)c3cccs3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P03 compound treatment 0.243 -0.01 -0.54 -0.5374 -1.0 3212841 TimTec1_006317 Fc1cc(Cl)c(cc1F)C(=O)Nc2cc(cc(c2)C(=O)N3CCOCC3)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P04 compound treatment 0.299 0.046 2.47 2.4719 1.0 3088333 TimTec1_006318 CN(CC(=O)Nc1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P05 compound treatment 0.256 0.003 0.16 0.1612 1.0 3088334 TimTec1_006319 CCCCS(=O)(=O)Nc1ccc2ncn(C)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P06 compound treatment 0.252 -0.001 -0.05 -0.0537 -1.0 3212842 TimTec1_006320 Cc1cccc(C)c1NC(=S)NC2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P07 compound treatment 0.305 0.052 2.79 2.7944 1.0 3212843 TimTec1_006321 CCOC(=O)C1=C(N)N2C(=O)C(C)SC2=C(C1c3cccc(OC)c3)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P08 compound treatment 0.254 0.001 0.05 0.0537 1.0 3088336 TimTec1_006322 COc1nc(NCC2CCCO2)nc(n1)N3CC4CC(C3)c5cccc(=O)n5C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P09 compound treatment 0.379 0.126 6.77 6.771 1.0 3212844 TimTec1_006323 CCOc1ccc(CCNC(=C2C(=O)CCCC2=O)CC)cc1OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P10 compound treatment 0.261 0.008 0.43 0.4299 1.0 3212845 TimTec1_006324 CCc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C)(C)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P11 compound treatment 0.259 0.006 0.32 0.3224 1.0 3088339 TimTec1_006325 COC(=O)C1C(C)CC2=C(C(Nc3ccccc3N2)c4cccc(Br)c4)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P12 compound treatment 0.313 0.06 3.22 3.2243 1.0 3212846 TimTec1_006326 O=C(NCC1(CC2CC3CC(C2)C1)C3)c4nc5ncccn5n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P13 compound treatment 0.348 0.095 5.11 5.1051 1.0 3088341 TimTec1_006327 CC1Cn2c(COc3ccccc3)nnc2S1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P14 compound treatment 0.243 -0.01 -0.54 -0.5374 -1.0 3212847 TimTec1_006328 CN(C)c1nc(Oc2ccc(=O)n(C)n2)nc(n1)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P15 compound treatment 0.231 -0.022 -1.18 -1.1822 -1.0 3088343 TimTec1_006329 CC(C)(C)NC(=O)CSc1nnnn1C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P16 compound treatment 0.241 -0.012 -0.64 -0.6449 -1.0 1353461 TimTec1_006330 OCC1CCCN(C1)C(=S)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P17 compound treatment 0.25 -0.003 -0.16 -0.1612 -1.0 3088414 TimTec1_006331 C1CCN(C1)c2nc(nc(n2)n3ccnc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P18 compound treatment 0.231 -0.022 -1.18 -1.1822 -1.0 3212848 TimTec1_006332 CCOC(=O)[C@H]1NC(=O)C[C@H]1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P19 compound treatment 0.427 0.174 9.35 9.3504 1.0 3088418 TimTec1_006333 COc1ccc(cc1)C2=CC(NC(=S)N2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P20 compound treatment 0.279 0.026 1.4 1.3972 1.0 3212849 TimTec1_006334 CCCNC1=C(C(=O)Cc2ccc(OCC)c(OCC)c2)C(=O)CC(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P21 compound treatment 0.24 -0.013 -0.7 -0.6986 -1.0 3212850 TimTec1_006335 O=C1CC(C2=C(CCCC2=O)N1c3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P22 compound treatment 0.254 0.001 0.05 0.0537 1.0 3088421 TimTec1_006336 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)NC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P23 mock treatment 0.24 -0.013 -0.7 -0.6986 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2080 P24 mock treatment 0.252 -0.001 -0.05 -0.0537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A01 compound treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 3212851 TimTec1_006337 NC(=O)C(Cc1ccccc1)NC(=O)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A02 compound treatment 0.324 0.0783 4.21 4.2077 1.0 3088424 TimTec1_006338 CCCc1nc(Sc2nncn2C)c3sc(=S)n(c4ccccc4)c3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A03 compound treatment 0.288 0.0423 2.27 2.2731 1.0 3212852 TimTec1_006339 Fc1ccc(NC(=O)c2ccccc2NS(=O)(=O)N3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A04 compound treatment 0.311 0.0653 3.51 3.5091 1.0 1402109 TimTec1_006340 Cc1ccc2n3CCN(CCC(=O)N)c4cccc(c2c1)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A05 compound treatment 0.276 0.0303 1.63 1.6283 1.0 3088426 TimTec1_006341 Cc1ccc(cc1CNC(=O)c2ccco2)c3nn(C)c(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A06 compound treatment 0.315 0.0693 3.72 3.724 1.0 1292864 TimTec1_006342 CCSC1=C(C#N)C(=N)n2c1cc3CCCCc32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A07 compound treatment 0.284 0.0383 2.06 2.0582 1.0 3088428 TimTec1_006343 Cc1cc2NC(Nc3ccc(F)c(Cl)c3)Sn2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A08 compound treatment 0.343 0.0973 5.23 5.2287 1.0 3212922 TimTec1_006344 CC(C)(O)C#Cc1ccc(s1)C(=O)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A09 compound treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 3088430 TimTec1_006345 Cc1cc(c(C)s1)S(=O)(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A10 compound treatment 0.247 0.0013 0.07 0.0699 1.0 1848161 TimTec1_006346 Cc1cc(C)c(C#N)c(SCC(=O)NC2CCCCC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A11 compound treatment 0.244 -0.0017 -0.09 -0.0914 -1.0 3088432 TimTec1_006347 CCNC(=S)N1CCCC(C1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A12 compound treatment 0.405 0.159 8.56 8.5604 1.0 3212923 TimTec1_006348 CCOc1ccc(NC(=S)N2CCSC2c3ccc(C#CC(C)(C)O)s3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A13 compound treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 3088434 TimTec1_006349 OC(=O)CCc1cc(Cl)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A14 compound treatment 0.275 0.0293 1.57 1.5745 1.0 3212924 TimTec1_006350 COc1ccc(cc1)c2c(C)c3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A15 compound treatment 0.262 0.0163 0.88 0.8759 1.0 3212925 TimTec1_006351 FC(F)(F)c1ccccc1N2C(=O)CC(C3=C2CCCC3=O)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A16 compound treatment 0.499 0.253 13.61 13.6118 1.0 3088437 TimTec1_006352 CCOc1ccc(cc1)c2cc3ccc(cc3oc2=O)N(CC)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A17 compound treatment 0.363 0.117 6.3 6.3035 1.0 3088438 TimTec1_006353 O=C/1NC(=N\C1=C/c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A18 compound treatment 0.308 0.0623 3.35 3.3479 1.0 3212926 TimTec1_006354 CC(=O)n1c(=O)sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A19 compound treatment 0.279 0.0333 1.79 1.7895 1.0 3212927 TimTec1_006355 COc1ccc(cc1)C2OCc3ccccc3N2C(=O)c4cccc(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A20 compound treatment 0.263 0.0173 0.93 0.9297 1.0 1648398 TimTec1_006356 Oc1ccc2ccccc2c1C(NC(=O)C3CCCCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A21 compound treatment 0.288 0.0423 2.27 2.2731 1.0 3088507 TimTec1_006357 CCN(CC)C(=O)Cn1nnc(n1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A22 compound treatment 0.338 0.0923 4.96 4.96 1.0 1222563 TimTec1_006358 CC(Oc1ccccc1)C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A23 mock treatment 0.264 0.0183 0.98 0.9834 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 A24 mock treatment 0.263 0.0173 0.93 0.9297 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B01 compound treatment 0.432 0.186 10.01 10.0114 1.0 1265521 TimTec1_006359 O=C(CCc1ccccc1)c2ccc3OCCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B02 compound treatment 0.25 0.0043 0.23 0.2311 1.0 1216112 TimTec1_006360 Cc1nn(c2CC3C(c12)C3(C)C)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B03 compound treatment 0.325 0.0793 4.26 4.2614 1.0 1782446 TimTec1_006361 NC(=C(C#N)C#N)/C(=C/c1c[nH]c2ccccc12)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B04 compound treatment 0.598 0.352 18.93 18.9319 1.0 1431158 TimTec1_006362 CCN(CC)c1ccc2c(cc(=O)oc2c1)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B05 compound treatment 0.501 0.255 13.72 13.7193 1.0 1471466 TimTec1_006363 COc1ccc2[nH]c3C(=O)NC(C)Cc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B06 compound treatment 0.293 0.0473 2.54 2.5418 1.0 1510603 TimTec1_006364 COc1ccc(CNc2ccc(C)c(C)c2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B07 compound treatment 0.251 0.0053 0.28 0.2848 1.0 1598446 TimTec1_006365 Brc1ccc(NC(=O)C2(CCCC2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B08 compound treatment 0.299 0.0533 2.86 2.8642 1.0 1697979 TimTec1_006366 O=C(Nc1ccccc1)C2CC3c4ccccc4C2c5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B09 compound treatment 0.244 -0.0017 -0.09 -0.0914 -1.0 1393320 TimTec1_006367 OC(=O)CC(Cc1ccc(Cl)cc1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B10 compound treatment 0.388 0.142 7.65 7.6469 1.0 1217422 TimTec1_006368 CCOC(=O)c1c(NC(=O)c2ccc(OC)cc2)sc3CCC(C)Cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B11 compound treatment 0.265 0.0193 1.04 1.0371 1.0 3088515 TimTec1_006369 OC(=O)/C(=C\c1cccs1)/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B12 compound treatment 0.247 0.0013 0.07 0.0699 1.0 1183980 TimTec1_006370 CN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B13 compound treatment 0.248 0.0023 0.12 0.1236 1.0 1620531 TimTec1_006371 CCc1nc(N)c(C#N)c(c1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B14 compound treatment 0.408 0.162 8.72 8.7217 1.0 3212929 TimTec1_006372 CCCCn1c2nc(cn2c3ccccc13)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B15 compound treatment 0.25 0.0043 0.23 0.2311 1.0 1922330 TimTec1_006373 COC(=O)CCS(=O)(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B16 compound treatment 0.398 0.152 8.18 8.1843 1.0 3088518 TimTec1_006374 Clc1ccc(cc1)c2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B17 compound treatment 0.516 0.27 14.53 14.5254 1.0 1683391 TimTec1_006375 Clc1ccc(cc1Cl)N2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B18 compound treatment 0.455 0.209 11.25 11.2473 1.0 1131054 TimTec1_006376 Nc1ccc(C(=O)OCC(=O)c2ccc(Br)cc2)c(O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B19 compound treatment 0.261 0.0153 0.82 0.8222 1.0 1106472 TimTec1_006377 COC(=O)c1ccc(C)c(c1)N(CCO)CCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B20 compound treatment 0.27 0.0243 1.31 1.3058 1.0 3088521 TimTec1_006378 c1sc(nc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B21 compound treatment 0.503 0.257 13.83 13.8268 1.0 1414393 TimTec1_006379 COc1cc2CCN(Cc2cc1OC)C(=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B22 compound treatment 0.263 0.0173 0.93 0.9297 1.0 3088523 TimTec1_006380 CC(C)COc1ccc2[nH]c3CCCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B23 mock treatment 0.303 0.0573 3.08 3.0792 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 B24 mock treatment 0.239 -0.0067 -0.36 -0.36 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C01 compound treatment 0.238 -0.0077 -0.41 -0.4138 -1.0 3212930 TimTec1_006381 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C02 compound treatment 0.249 0.0033 0.18 0.1773 1.0 3088525 TimTec1_006382 CC1(C)OC(=O)N(CC(=O)Nc2ccc(F)cc2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C03 compound treatment 0.315 0.0693 3.72 3.724 1.0 3212931 TimTec1_006383 Fc1ccc(cc1)c2cn3c(c(nc3[nH]2)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C04 compound treatment 0.268 0.0223 1.2 1.1984 1.0 3212932 TimTec1_006384 COCC(=O)Nc1ccc(CC#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C05 compound treatment 0.415 0.169 9.1 9.0978 1.0 3212933 TimTec1_006385 Cc1ccc(cc1)c2nn(CC(=O)Nc3cccnc3)c(=O)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C06 compound treatment 0.25 0.0043 0.23 0.2311 1.0 3087470 TimTec1_006386 CC1CN(CC(C)O1)C(=O)c2scc3OCCOc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C07 compound treatment 0.503 0.257 13.83 13.8268 1.0 3212934 TimTec1_006387 O=C(OCc1ccccc1)c2cccc(c2)c3nnn(Cc4ccccc4)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C08 compound treatment 0.204 -0.0417 -2.24 -2.2409 -1.0 3087472 TimTec1_006388 COc1ccc(cc1)C(=O)Oc2c(C)cc(cc2C)C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C09 compound treatment 0.439 0.193 10.39 10.3875 1.0 3212935 TimTec1_006389 NC(=O)c1cccc(c1)S(=O)(=O)N2CC(CC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C10 compound treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 3087474 TimTec1_006390 NN(C(=O)N)c1nc(nc(n1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C11 compound treatment 0.253 0.0073 0.39 0.3923 1.0 3212936 TimTec1_006391 Clc1ccc2[nH]c(=O)c(N3CCCC3)c(c4ccccc4)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C12 compound treatment 0.256 0.0103 0.55 0.5535 1.0 3212937 TimTec1_006392 CCOC(=O)c1c(N)nn(C(=O)CC)c1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C13 compound treatment 0.56 0.314 16.89 16.8898 1.0 2103793 TimTec1_006393 COc1ccc(/C=C/C(=O)\C=C\c2ccc(OC)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C14 compound treatment 0.303 0.0573 3.08 3.0792 1.0 3087477 TimTec1_006394 Cc1ccc2c(C)c(c3ccccc3)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C15 compound treatment 0.284 0.0383 2.06 2.0582 1.0 3212938 TimTec1_006395 CCOC(=O)C1C(CC(=CC1=O)N2CCOCC2)c3cccc(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C16 compound treatment 0.28 0.0343 1.84 1.8432 1.0 3087479 TimTec1_006396 Cc1c(CC(=O)O)c(=O)oc2c(O)c(O)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C17 compound treatment 0.487 0.241 12.97 12.967 1.0 3212939 TimTec1_006397 COc1cc2c(cc1NS(=O)(=O)c3ccc(cc3)N4CCCC4=O)oc5ccccc52 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C18 compound treatment 0.26 0.0143 0.77 0.7685 1.0 1047503 TimTec1_006398 OC(=O)c1ccccc1C(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C19 compound treatment 0.27 0.0243 1.31 1.3058 1.0 3212940 TimTec1_006399 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4cc(OC)c(OC)cc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C20 compound treatment 0.403 0.157 8.45 8.453 1.0 1299646 TimTec1_006400 Cc1ccc(cc1)C(=O)Nc2ccc(Cl)cn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C21 compound treatment 0.41 0.164 8.83 8.8291 1.0 3087483 TimTec1_006401 CCN1C(=O)OC(C)(CCc2ccccc2)C1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C22 compound treatment 0.284 0.0383 2.06 2.0582 1.0 1518127 TimTec1_006402 CC(NC(=O)Cc1ccc(Br)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C23 mock treatment 0.263 0.0173 0.93 0.9297 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 C24 mock treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D01 compound treatment 0.304 0.0583 3.13 3.1329 1.0 1621697 TimTec1_006403 Clc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc4ccc(Cl)cc4)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D02 compound treatment 0.293 0.0473 2.54 2.5418 1.0 1652889 TimTec1_006404 CC(C)COc1ccc(cc1)C(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D03 compound treatment 0.331 0.0853 4.58 4.5838 1.0 3211230 TimTec1_006405 COc1ccc(/C=N/c2c(nc3ccccn23)c4ccco4)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D04 compound treatment 0.251 0.0053 0.28 0.2848 1.0 1434704 TimTec1_006406 OC(=O)c1ccc(CN2CCCCC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D05 compound treatment 0.272 0.0263 1.41 1.4133 1.0 3087486 TimTec1_006407 CCCCc1ccc(NC(=O)C(C)CC)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D06 compound treatment 0.256 0.0103 0.55 0.5535 1.0 1411188 TimTec1_006408 CCOc1ccc(NC(=O)c2c3CCCCc3nc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D07 compound treatment 0.256 0.0103 0.55 0.5535 1.0 1481913 TimTec1_006409 CCOC(=O)C(Cc1ccccc1)C(=O)Nc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D08 compound treatment 0.256 0.0103 0.55 0.5535 1.0 3211231 TimTec1_006410 COC(=O)CSc1cc(C)nc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D09 compound treatment 0.298 0.0523 2.81 2.8105 1.0 1332614 TimTec1_006411 CN(C)CCOC(=O)c1sc2ccccc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D10 compound treatment 0.275 0.0293 1.57 1.5745 1.0 1699312 TimTec1_006412 CC(=O)Nc1sc2CCCCCc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D11 compound treatment 0.302 0.0563 3.03 3.0254 1.0 1281983 TimTec1_006413 COc1cc(N)ccc1NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D12 compound treatment 0.27 0.0243 1.31 1.3058 1.0 3211232 TimTec1_006414 Brc1ccc(cc1)c2cc3-c4ccccc4CCn3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D13 compound treatment 0.261 0.0153 0.82 0.8222 1.0 1235800 TimTec1_006415 N(c1ccccc1)c2nc(nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D14 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 1261113 TimTec1_006416 OC(=O)C1CCCCC1C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D15 compound treatment 0.36 0.114 6.14 6.1422 1.0 1120499 TimTec1_006417 O=C(CCN1Cc2ccccc2C1)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D16 compound treatment 0.372 0.126 6.79 6.7871 1.0 3211233 TimTec1_006418 Cc1ccc(NC2=CC(=O)CC(C2)c3ccc(Cl)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D17 compound treatment 0.406 0.16 8.61 8.6142 1.0 1314383 TimTec1_006419 O=C(COc1ccc2ccccc2c1)N3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D18 compound treatment 0.26 0.0143 0.77 0.7685 1.0 3211234 TimTec1_006420 CC(=O)N/C(=C/c1ccccc1)/C(=O)Nc2ccc(C)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D19 compound treatment 0.25 0.0043 0.23 0.2311 1.0 1461637 TimTec1_006421 CCC1C(NC(CC1(O)CC=C)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D20 compound treatment 0.295 0.0493 2.65 2.6493 1.0 1679474 TimTec1_006422 CC1=C(CC(=C(C)N1)C(=O)c2ccccc2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D21 compound treatment 0.285 0.0393 2.11 2.1119 1.0 1577332 TimTec1_006423 CC1(C)Cc2nc(N3CCCC3)c(C#N)cc2CO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D22 compound treatment 0.372 0.126 6.79 6.7871 1.0 3088079 TimTec1_006424 CN(C)C(=O)CCSc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D23 mock treatment 0.242 -0.0037 -0.2 -0.1988 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 D24 mock treatment 0.239 -0.0067 -0.36 -0.36 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E01 compound treatment 0.238 -0.0077 -0.41 -0.4138 -1.0 3211235 TimTec1_006425 Cc1nc(C)c(C(=O)O)c(c2ccc(F)cc2)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E02 compound treatment 0.272 0.0263 1.41 1.4133 1.0 3088081 TimTec1_006426 CCOc1nc(C)nc2n(C)c(=S)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E03 compound treatment 0.237 -0.0087 -0.47 -0.4675 -1.0 3088082 TimTec1_006427 CC(C)(C)C(N)Cn1ccnc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E04 compound treatment 0.259 0.0133 0.71 0.7147 1.0 3211236 TimTec1_006428 NC(=O)c1cc2ccccc2nc1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E05 compound treatment 0.278 0.0323 1.74 1.7357 1.0 1461983 TimTec1_006429 CC(C)NC(=S)N1CCC(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E06 compound treatment 0.337 0.0913 4.91 4.9063 1.0 3211237 TimTec1_006430 CC12CCC3C(CC=C4CC(O)CCC34C)C2C/C(=C\c5ccc(cc5)C(F)(F)F)/C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E07 compound treatment 0.448 0.202 10.87 10.8712 1.0 3088086 TimTec1_006431 CCOC(=O)Cn1nnc(n1)c2ccc(OCc3ccccc3F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E08 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 3088087 TimTec1_006432 CC(=O)Oc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E09 compound treatment 0.279 0.0333 1.79 1.7895 1.0 3211238 TimTec1_006433 COC(=O)/N=c/1\[cH-][n+](no1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E10 compound treatment 0.271 0.0253 1.36 1.3596 1.0 3088089 TimTec1_006434 N#Cc1c(SCc2nc3ccccc3[nH]2)nc(cc1c4ccco4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E11 compound treatment 0.311 0.0653 3.51 3.5091 1.0 1643293 TimTec1_006435 S=C(Nc1cccnc1)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E12 compound treatment 0.248 0.0023 0.12 0.1236 1.0 3211239 TimTec1_006436 CCS(=O)(=O)c1nnnn1c2ccccc2S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E13 compound treatment 0.239 -0.0067 -0.36 -0.36 -1.0 3088092 TimTec1_006437 CC1Cc2scc[n+]2-c3ccccc3N1C=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E14 compound treatment 0.279 0.0333 1.79 1.7895 1.0 3211240 TimTec1_006438 Cc1c(c2ccc(Br)cc2)c(=O)oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E15 compound treatment 0.263 0.0173 0.93 0.9297 1.0 1314711 TimTec1_006439 Oc1cccc(NC(=S)Nc2cccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E16 compound treatment 0.281 0.0353 1.9 1.8969 1.0 3088158 TimTec1_006440 CCC(=O)c1cc(N)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E17 compound treatment 0.37 0.124 6.68 6.6796 1.0 3088160 TimTec1_006441 COC(=O)C(NS(=O)(=O)c1ccc(cc1)N2CCCC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E18 compound treatment 0.417 0.171 9.21 9.2053 1.0 1280834 TimTec1_006442 O=C(c1ccc2[nH]c(=O)oc2c1)c3ccc4[nH]c(=O)oc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E19 compound treatment 0.309 0.0633 3.4 3.4016 1.0 3088162 TimTec1_006443 Cc1cn(CCOc2ccc(Cl)cc2)c(=O)[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E20 compound treatment 0.483 0.237 12.75 12.752 1.0 1786935 TimTec1_006444 COc1ccc2nc(C)cc(SCC(=O)c3ccc(Cl)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E21 compound treatment 0.333 0.0873 4.69 4.6913 1.0 3088165 TimTec1_006445 CCn1c2sc(C)nc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E22 compound treatment 0.275 0.0293 1.57 1.5745 1.0 1187778 TimTec1_006446 CCc1ccccc1NC(=O)Cc2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E23 mock treatment 0.252 0.0063 0.34 0.3385 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 E24 mock treatment 0.244 -0.0017 -0.09 -0.0914 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F01 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 1527015 TimTec1_006447 CC(C)Nc1nc(NC(C)C)nc(Nn2cnnc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F02 compound treatment 0.25 0.0043 0.23 0.2311 1.0 3088167 TimTec1_006448 OC(=O)c1ccccc1C(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F03 compound treatment 0.323 0.0773 4.15 4.1539 1.0 1774253 TimTec1_006449 CC(=C)C1Cc2cc3ccc(=O)oc3cc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F04 compound treatment 0.531 0.285 15.33 15.3314 1.0 1327284 TimTec1_006450 O=C(Nc1ccc(cc1)c2csc(n2)c3ccccc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F05 compound treatment 0.248 0.0023 0.12 0.1236 1.0 3211241 TimTec1_006451 CCC(C)(C)C(=O)NC(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F06 compound treatment 0.3 0.0543 2.92 2.918 1.0 1238234 TimTec1_006452 Cc1cc(C)n(n1)c2cc(Nc3ccc(C)cc3)nc(n2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F07 compound treatment 0.278 0.0323 1.74 1.7357 1.0 1039376 TimTec1_006453 CCOC(=O)CNc1cccc(c1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F08 compound treatment 0.49 0.244 13.13 13.1282 1.0 1251321 TimTec1_006454 Oc1c(C(=O)NCc2cccnc2)c(=O)n(CC=C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F09 compound treatment 0.259 0.0133 0.71 0.7147 1.0 3211242 TimTec1_006455 OC(CC#CCN1CCCC1)(C2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F10 compound treatment 0.506 0.26 13.99 13.988 1.0 1460065 TimTec1_006456 COc1ccc(OCc2nc3ccccc3n2CC(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F11 compound treatment 0.344 0.0983 5.28 5.2824 1.0 1200425 TimTec1_006457 CC(=O)N1NC(CC1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F12 compound treatment 0.275 0.0293 1.57 1.5745 1.0 1370319 TimTec1_006458 C=CCn1c(=O)c2c3CCCCc3sc2[nH]c1=S 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F13 compound treatment 0.314 0.0683 3.67 3.6703 1.0 3211243 TimTec1_006459 Cc1cc(Oc2ccccc2)nc(n1)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F14 compound treatment 0.371 0.125 6.73 6.7334 1.0 1175134 TimTec1_006460 Nc1nc(cs1)c2ccc(OCc3ccc(Br)cc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F15 compound treatment 0.491 0.245 13.18 13.1819 1.0 3088175 TimTec1_006461 COc1ccc(cc1)[S+]2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F16 compound treatment 0.269 0.0233 1.25 1.2521 1.0 1456348 TimTec1_006462 O=C(N1CCOCC1)C2(CC3CC4C2)CC(C3)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F17 compound treatment 0.383 0.137 7.38 7.3782 1.0 1618640 TimTec1_006463 Cc1sc2ncnc(NCc3cccnc3)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F18 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 1467012 TimTec1_006464 COc1ccc(NC(=O)C2CCCCN2N)cc1OCC(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F19 compound treatment 0.343 0.0973 5.23 5.2287 1.0 1706198 TimTec1_006465 CCC(=O)N1C(CC2CC=C(C)C2(C)C)C3=C(CC(C)(C)CC3=O)Nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F20 compound treatment 0.535 0.289 15.55 15.5464 1.0 1345040 TimTec1_006466 CCN(CC)c1ccc2cc(c3nnc(o3)c4cccnc4)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F21 compound treatment 0.253 0.0073 0.39 0.3923 1.0 1688068 TimTec1_006467 NC(=O)c1ccccc1NC(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F22 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 3248073 TimTec1_006468 Cc1n[nH]c(C)c1[C@]2(C[C@H]3C[C@H]4C[C@H](C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F23 mock treatment 0.254 0.0083 0.45 0.446 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 F24 mock treatment 0.235 -0.0107 -0.57 -0.575 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G01 compound treatment 0.414 0.168 9.04 9.0441 1.0 3211441 TimTec1_006469 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G02 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 3088256 TimTec1_006470 Fc1ccc(OC(=O)c2nsc(Cl)c2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G03 compound treatment 0.252 0.0063 0.34 0.3385 1.0 3211442 TimTec1_006471 CC(C)(C)C(CN1CCCC1)OC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G04 compound treatment 0.246 3.0E-4 0.02 0.0161 1.0 3088258 TimTec1_006472 NC(=N)NC(=N)N1N=CCC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G05 compound treatment 0.286 0.0403 2.17 2.1656 1.0 3211443 TimTec1_006473 Cc1ccc(cc1)C(=O)OCC2OC3OC(C)(C)OC3C2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G06 compound treatment 0.39 0.144 7.75 7.7544 1.0 3211444 TimTec1_006474 NS(=O)(=O)c1ccc(cc1)S(=O)(=O)NCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G07 compound treatment 0.269 0.0233 1.25 1.2521 1.0 1310353 TimTec1_006475 S=C(NC1CCCCCCC1)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G08 compound treatment 0.257 0.0113 0.61 0.6072 1.0 3088261 TimTec1_006476 CC(=O)Oc1ccc(C)cc1C(O)(C(F)(F)F)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G09 compound treatment 0.25 0.0043 0.23 0.2311 1.0 3211445 TimTec1_006477 CSC1=NC(C)(C)CC2(CC(c3cccs3)c4ccc(O)c(O)c4O2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G10 compound treatment 0.247 0.0013 0.07 0.0699 1.0 3088263 TimTec1_006478 Cc1cc(=O)[nH]c2n(nc(O)c12)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G11 compound treatment 0.256 0.0103 0.55 0.5535 1.0 3211446 TimTec1_006479 CCCN(CC1CC1)C(=S)Nc2cccc(C)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G12 compound treatment 0.271 0.0253 1.36 1.3596 1.0 3088265 TimTec1_006480 OC(=O)c1cc(=O)c2cc(Br)ccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G13 compound treatment 0.273 0.0273 1.47 1.467 1.0 3211447 TimTec1_006481 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4c(O)cccc4OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G14 compound treatment 0.331 0.0853 4.58 4.5838 1.0 1098644 TimTec1_006482 C=CCOc1ccc2ccc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G15 compound treatment 0.476 0.23 12.38 12.3758 1.0 3211448 TimTec1_006483 O=C(Cc1ccccc1)N2CCN(CC2)c3nc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G16 compound treatment 0.287 0.0413 2.22 2.2194 1.0 1202156 TimTec1_006484 CCC(C)n1ncn(c2ccc(cc2)N3CCN(CC3)c4ccc(OC)cc4)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G17 compound treatment 0.294 0.0483 2.6 2.5955 1.0 3088269 TimTec1_006485 CC1CCc2c(C1)sc3nc(SCc4nc(no4)c5ccccc5)n(C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G18 compound treatment 0.252 0.0063 0.34 0.3385 1.0 3211449 TimTec1_006486 COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G19 compound treatment 0.442 0.196 10.55 10.5488 1.0 3211450 TimTec1_006487 CCNc1nc(NCC)n2c(SCC(=O)c3cccs3)nnc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G20 compound treatment 0.275 0.0293 1.57 1.5745 1.0 3088271 TimTec1_006488 Cc1ccc(SCC(=O)Nc2ccc(C)cc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G21 compound treatment 0.43 0.184 9.9 9.9039 1.0 3211451 TimTec1_006489 Fc1ccc(NC2=CC(CC2=O)N3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G22 compound treatment 0.248 0.0023 0.12 0.1236 1.0 1498860 TimTec1_006490 C(C1Cc2ccccc2O1)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G23 mock treatment 0.251 0.0053 0.28 0.2848 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 G24 mock treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H01 compound treatment 0.246 3.0E-4 0.02 0.0161 1.0 1353778 TimTec1_006491 CCOC(=O)CC1(CCOC(C)(C)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H02 compound treatment 0.25 0.0043 0.23 0.2311 1.0 1342963 TimTec1_006492 CN1CCC2(CCN(Cc3ccccc3)C2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H03 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 3211452 TimTec1_006493 Cc1cc(nc(c1C)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H04 compound treatment 0.26 0.0143 0.77 0.7685 1.0 1735148 TimTec1_006494 Cc1cccc(Nc2cc(C)nc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H05 compound treatment 0.285 0.0393 2.11 2.1119 1.0 3088347 TimTec1_006495 CCOC(=O)c1c(C)n(C)c2ccc(OCC)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H06 compound treatment 0.327 0.0813 4.37 4.3689 1.0 3211453 TimTec1_006496 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)Nc3cccc4ccccc34)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H07 compound treatment 0.26 0.0143 0.77 0.7685 1.0 1313366 TimTec1_006497 CCOc1ccc(CNC2CCCc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H08 compound treatment 0.286 0.0403 2.17 2.1656 1.0 3211454 TimTec1_006498 NC1=C(C#N)C(C(=C(N)S1)C#N)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H09 compound treatment 0.294 0.0483 2.6 2.5955 1.0 1379894 TimTec1_006499 CC(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H10 compound treatment 0.267 0.0213 1.14 1.1446 1.0 3088351 TimTec1_006500 COc1ccc(cc1)c2c(C)oc3ccc(C)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H11 compound treatment 0.337 0.0913 4.91 4.9063 1.0 1710850 TimTec1_006501 CCCc1cc(O)c2c(C)cc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H12 compound treatment 0.376 0.13 7.0 7.002 1.0 3211455 TimTec1_006502 Cc1ccc(cc1)C(=O)NCCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H13 compound treatment 0.459 0.213 11.46 11.4623 1.0 1733570 TimTec1_006503 Cc1ccc(Nc2nnc(c3ccccc3)c4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H14 compound treatment 0.245 -7.0E-4 -0.04 -0.0376 -1.0 1118121 TimTec1_006504 CC1(C)CC(=C(CC2C(=O)CC(C)(C)CC2=O)C(=O)C1)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H15 compound treatment 0.244 -0.0017 -0.09 -0.0914 -1.0 1591866 TimTec1_006505 O=S1(=O)CCC(C1)NC2CCS(=O)(=O)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H16 compound treatment 0.261 0.0153 0.82 0.8222 1.0 3088354 TimTec1_006506 CC(C)(C)S(=O)(=O)c1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H17 compound treatment 0.309 0.0633 3.4 3.4016 1.0 1442109 TimTec1_006507 CCC1C(=C(NC2=C1C(=O)CC(C)(C)C2)SC)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H18 compound treatment 0.247 0.0013 0.07 0.0699 1.0 1161095 TimTec1_006508 COc1cccc(CNC2CCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H19 compound treatment 0.399 0.153 8.24 8.238 1.0 1180009 TimTec1_006509 Brc1ccc(o1)C(=O)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H20 compound treatment 0.26 0.0143 0.77 0.7685 1.0 1788667 TimTec1_006510 COCC(C)NC(=O)c1c(C)onc1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H21 compound treatment 0.248 0.0023 0.12 0.1236 1.0 1569691 TimTec1_006511 CC(C)CC(=O)NCc1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H22 compound treatment 0.286 0.0403 2.17 2.1656 1.0 1573756 TimTec1_006512 OCCNc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1Cc5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H23 mock treatment 0.249 0.0033 0.18 0.1773 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 H24 mock treatment 0.239 -0.0067 -0.36 -0.36 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I01 compound treatment 0.261 0.0153 0.82 0.8222 1.0 3211456 TimTec1_006513 NC(=O)C(Cc1ccccc1)NC(=O)c2ccccc2Sc3ccccc3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I02 compound treatment 0.49 0.244 13.13 13.1282 1.0 3088358 TimTec1_006514 N#Cc1ccc(CSc2nnc(c3cccs3)n2c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I03 compound treatment 0.527 0.281 15.12 15.1165 1.0 3088360 TimTec1_006515 CCN(Cc1ccccc1)C(=O)CSc2nc(C)cc3COC(=O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I04 compound treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 3211457 TimTec1_006516 CC1(C)OCC(O1)C2OC(=O)C3OC(C)(C)OC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I05 compound treatment 0.516 0.27 14.53 14.5254 1.0 3211458 TimTec1_006517 Cc1ccc2ncc(cc2c1)c3ccc4c(N)c(C)ccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I06 compound treatment 0.249 0.0033 0.18 0.1773 1.0 3088362 TimTec1_006518 CN1C(=O)N(C)C(=O)C(C2CCC3OCC2O3)(C4CCC5OCC4O5)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I07 compound treatment 0.331 0.0853 4.58 4.5838 1.0 3211459 TimTec1_006519 COc1ccc(cc1)C2N(C(=O)C32CCCC3)c4ccc(OC)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I08 compound treatment 0.253 0.0073 0.39 0.3923 1.0 3088364 TimTec1_006520 CCOC(=O)C1CNC(=S)NC1(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I09 compound treatment 0.292 0.0463 2.49 2.4881 1.0 3211538 TimTec1_006521 CC1(C)CC2(CC(c3ccccc3F)c4cc(Cl)c(O)cc4O2)NC(=S)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I10 compound treatment 0.26 0.0143 0.77 0.7685 1.0 3211539 TimTec1_006522 CC1(C)Cc2c(CS1)c(nc3sc4c(Cl)nnnc4c23)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I11 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 3088367 TimTec1_006523 CCNCC1Cc2ccccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I12 compound treatment 0.496 0.25 13.45 13.4506 1.0 3088369 TimTec1_006524 Cc1ccc2oc(cc(=O)c2c1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I13 compound treatment 0.252 0.0063 0.34 0.3385 1.0 3211540 TimTec1_006525 CN(C)c1nc(nc2n(c3ccccc3)c(=S)sc12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I14 compound treatment 0.341 0.0953 5.12 5.1212 1.0 3088443 TimTec1_006526 CCOc1cc(=O)oc2ccc(Cl)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I15 compound treatment 0.275 0.0293 1.57 1.5745 1.0 1518517 TimTec1_006527 CCCN(CC1CC1)C(=S)Nc2ccc(OCC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I16 compound treatment 0.279 0.0333 1.79 1.7895 1.0 3211541 TimTec1_006528 COc1ccc(cc1Br)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I17 compound treatment 0.26 0.0143 0.77 0.7685 1.0 3211542 TimTec1_006529 OC(=O)CC(N1C(=O)CCC1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I18 compound treatment 0.245 -7.0E-4 -0.04 -0.0376 -1.0 3088447 TimTec1_006530 COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I19 compound treatment 0.492 0.246 13.24 13.2356 1.0 1478025 TimTec1_006531 COc1ccc2CN(C(=O)c2c1OC)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I20 compound treatment 0.258 0.0123 0.66 0.661 1.0 3088449 TimTec1_006532 CNC(=O)CSc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I21 compound treatment 0.281 0.0353 1.9 1.8969 1.0 1596437 TimTec1_006533 S=C(NCCN1CCOCC1)Nc2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I22 compound treatment 0.293 0.0473 2.54 2.5418 1.0 1592947 TimTec1_006534 OC(=O)c1oc2ccccc2c1CSc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I23 mock treatment 0.239 -0.0067 -0.36 -0.36 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 I24 mock treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J01 compound treatment 0.25 0.0043 0.23 0.2311 1.0 1534128 TimTec1_006535 CCCCC1CCC(CC1)C(=O)OCC(=O)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J02 compound treatment 0.52 0.274 14.74 14.7403 1.0 1169194 TimTec1_006536 O=C(CSc1nsc(SCC(=O)N2CCCCC2)c1C#N)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J03 compound treatment 0.261 0.0153 0.82 0.8222 1.0 1496370 TimTec1_006537 COc1ccc(OCC(=O)NCC(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J04 compound treatment 0.311 0.0653 3.51 3.5091 1.0 1291245 TimTec1_006538 CCOc1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J05 compound treatment 0.249 0.0033 0.18 0.1773 1.0 3088453 TimTec1_006539 OC(=O)C1C(C2OC1C=C2)C(=O)Nc3cccc(c3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J06 compound treatment 0.387 0.141 7.59 7.5932 1.0 1271879 TimTec1_006540 O=C(Cc1cccs1)Nc2nc(cs2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J07 compound treatment 0.266 0.0203 1.09 1.0909 1.0 1072955 TimTec1_006541 COc1ccc(cc1)c2cc([nH]n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J08 compound treatment 0.278 0.0323 1.74 1.7357 1.0 3211543 TimTec1_006542 COc1cccc(c1)C2CC(n3ncc(C(=O)N4CCCCC4C)c3N2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J09 compound treatment 0.277 0.0313 1.68 1.682 1.0 1695584 TimTec1_006543 CC(=CCC(C)(C)C1OCCN1C(=O)c2ccccc2)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J10 compound treatment 0.302 0.0563 3.03 3.0254 1.0 1201910 TimTec1_006544 Cc1cccc2c(C)cc(SCCC(=O)O)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J11 compound treatment 0.283 0.0373 2.0 2.0044 1.0 1651502 TimTec1_006545 CC(C(=O)Nc1ccccc1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J12 compound treatment 0.233 -0.0127 -0.68 -0.6825 -1.0 1498972 TimTec1_006546 OC(=O)CCCC(=O)Nc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J13 compound treatment 0.332 0.0863 4.64 4.6376 1.0 1609094 TimTec1_006547 C(Nc1ccccn1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J14 compound treatment 0.332 0.0863 4.64 4.6376 1.0 1441843 TimTec1_006548 CCOC(=O)CC(=O)c1c[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J15 compound treatment 0.263 0.0173 0.93 0.9297 1.0 1692597 TimTec1_006549 COc1ccc(cc1)c2cc(C)nc(N)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J16 compound treatment 0.254 0.0083 0.45 0.446 1.0 1475363 TimTec1_006550 OC1(CC(=O)c2ccc(Cl)cc2)OC(=CC1=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J17 compound treatment 0.236 -0.0097 -0.52 -0.5213 -1.0 3088459 TimTec1_006551 CC1=CC(C)(C)N=C(Nc2nc(C)c3cc(C)cc(C)c3n2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J18 compound treatment 0.238 -0.0077 -0.41 -0.4138 -1.0 1438712 TimTec1_006552 CC(C)CC(=O)N1CCN(Cc2cccc(C)c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J19 compound treatment 0.484 0.238 12.81 12.8057 1.0 1215237 TimTec1_006553 O=C(Nc1ccccn1)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J20 compound treatment 0.247 0.0013 0.07 0.0699 1.0 1739248 TimTec1_006554 CC(C)CN(CC(C)C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J21 compound treatment 0.239 -0.0067 -0.36 -0.36 -1.0 3088529 TimTec1_006555 Cc1ccc(C)c(Cc2cc(Cl)ccc2Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J22 compound treatment 0.392 0.146 7.86 7.8619 1.0 1779992 TimTec1_006556 COc1ccc2oc(/C=C/N(C)C)c(C(=O)c3ccc(Br)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J23 mock treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 J24 mock treatment 0.233 -0.0127 -0.68 -0.6825 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K01 compound treatment 0.259 0.0133 0.71 0.7147 1.0 3088531 TimTec1_006557 CC(=O)Nc1cc(ccc1N2CCN(CC2)c3ccccc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K02 compound treatment 0.264 0.0183 0.98 0.9834 1.0 3211545 TimTec1_006558 COc1cc(OC)nc(NC(=O)C(C)C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K03 compound treatment 0.451 0.205 11.03 11.0324 1.0 3088533 TimTec1_006559 Cc1cc2COC(=O)c2c(SCc3ccc(Cl)cc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K04 compound treatment 0.471 0.225 12.11 12.1072 1.0 3211546 TimTec1_006560 COc1ccc(cc1)c2nc(no2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K05 compound treatment 0.255 0.0093 0.5 0.4998 1.0 1870743 TimTec1_006561 COc1cc(ccc1OC(C)C)C2NCCc3c2[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K06 compound treatment 0.256 0.0103 0.55 0.5535 1.0 3088535 TimTec1_006562 N#CC(=C1NN=NN1c2ccccc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K07 compound treatment 0.254 0.0083 0.45 0.446 1.0 3088537 TimTec1_006563 CC1(C)C(OC(=O)C(C)(C)C1=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K08 compound treatment 0.412 0.166 8.94 8.9366 1.0 3211547 TimTec1_006564 Cc1ccccc1COc2ccc(cc2)c3nnn[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K09 compound treatment 0.364 0.118 6.36 6.3572 1.0 3211548 TimTec1_006565 CC1(C)NC(=S)NC(=C1)/C=C/c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K10 compound treatment 0.26 0.0143 0.77 0.7685 1.0 3088539 TimTec1_006566 CCC1(C)Cc2c(C#N)c(N)n(c3ccccc3)c(=O)c2CO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K11 compound treatment 0.364 0.118 6.36 6.3572 1.0 3211549 TimTec1_006567 CC1(C)Cc2c(ccc3ccccc23)C(=N1)Sc4ccc(N)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K12 compound treatment 0.272 0.0263 1.41 1.4133 1.0 3088542 TimTec1_006568 Oc1ccc2c(c3ccccc3)c(c4ccccc4)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K13 compound treatment 0.269 0.0233 1.25 1.2521 1.0 3211550 TimTec1_006569 Cc1ccc(c(C)c1)n2nnnc2S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K14 compound treatment 0.548 0.302 16.24 16.245 1.0 3088543 TimTec1_006570 Cc1cccc(c1)c2cc(=O)c3cc(C)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K15 compound treatment 0.257 0.0113 0.61 0.6072 1.0 1568310 TimTec1_006571 CSc1ccccc1NC(=S)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K16 compound treatment 0.398 0.152 8.18 8.1843 1.0 3211551 TimTec1_006572 COc1cc(OC)c2c(=O)c(coc2c1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K17 compound treatment 0.38 0.134 7.22 7.217 1.0 3088546 TimTec1_006573 Cc1cn2c(nc(=S)nc2s1)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K18 compound treatment 0.346 0.1 5.39 5.3899 1.0 3088547 TimTec1_006574 Oc1cccc(c1)C2CC(=O)c3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K19 compound treatment 0.3 0.0543 2.92 2.918 1.0 3211552 TimTec1_006575 CCOC(=O)C1C2c3ccccc3O[C@]1(C)N=c4s/c(=C/c5ccc(OC)cc5)/c(=O)n24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K20 compound treatment 0.271 0.0253 1.36 1.3596 1.0 1160836 TimTec1_006576 COC(=O)C1C(C(C1c2ccccc2)C(=O)OCc3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K21 compound treatment 0.249 0.0033 0.18 0.1773 1.0 1239220 TimTec1_006577 COc1ccccc1NC(=S)N2CCCCC2CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K22 compound treatment 0.249 0.0033 0.18 0.1773 1.0 3211553 TimTec1_006578 C1CCc2c(C1)n(c3ccccc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K23 mock treatment 0.253 0.0073 0.39 0.3923 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 K24 mock treatment 0.249 0.0033 0.18 0.1773 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L01 compound treatment 0.387 0.141 7.59 7.5932 1.0 3088551 TimTec1_006579 CCn1c(=O)oc2cc(Br)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L02 compound treatment 0.259 0.0133 0.71 0.7147 1.0 1255982 TimTec1_006580 COc1cc(OC)c(cc1OC)C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L03 compound treatment 0.266 0.0203 1.09 1.0909 1.0 1156741 TimTec1_006581 CCC(C)NC(=O)c1ccccc1c2ccccc2C(=O)NC(C)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L04 compound treatment 0.251 0.0053 0.28 0.2848 1.0 1735137 TimTec1_006582 CC1CN(CC(C)O1)C(=O)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L05 compound treatment 0.265 0.0193 1.04 1.0371 1.0 3087493 TimTec1_006583 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L06 compound treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 1637432 TimTec1_006584 CC1(CN(CC2(C)CN(C1)C(=O)c3ccccc3)C(=O)c4ccccc4)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L07 compound treatment 0.25 0.0043 0.23 0.2311 1.0 3087495 TimTec1_006585 Brc1ccc(cc1)c2noc(n2)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L08 compound treatment 0.571 0.325 17.48 17.4809 1.0 1144835 TimTec1_006586 CCc1c(C)nc2cc(nn2c1O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L09 compound treatment 0.286 0.0403 2.17 2.1656 1.0 3087497 TimTec1_006587 CC(=O)OCCCn1c(C)nc2cc(Cl)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L10 compound treatment 0.28 0.0343 1.84 1.8432 1.0 3211639 TimTec1_006588 CCCCC(=O)C1CCC(CC1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L11 compound treatment 0.413 0.167 8.99 8.9904 1.0 1423564 TimTec1_006589 COc1cccc(NC(=O)CSc2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L12 compound treatment 0.25 0.0043 0.23 0.2311 1.0 3211640 TimTec1_006590 COc1ccc(cc1)C2N(CCO)C(=O)C(=C2C(=O)/C=C/c3ccccc3)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L13 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 1119356 TimTec1_006591 COc1ccc(Cl)cc1CN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L14 compound treatment 0.453 0.207 11.14 11.1399 1.0 1538287 TimTec1_006592 OCCn1c(cn2c1nc3ccccc32)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L15 compound treatment 0.277 0.0313 1.68 1.682 1.0 3211641 TimTec1_006593 Nc1nc(cc(c1C#N)c2ccc3OCOc3c2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L16 compound treatment 0.256 0.0103 0.55 0.5535 1.0 1511443 TimTec1_006594 CC(Cc1ccccc1)NC(=O)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L17 compound treatment 0.348 0.102 5.5 5.4974 1.0 1541381 TimTec1_006595 O=C(CCCN1C(=O)c2ccccc2C1=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L18 compound treatment 0.257 0.0113 0.61 0.6072 1.0 3087502 TimTec1_006596 ON=C(C(=O)c1ccccc1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L19 compound treatment 0.544 0.298 16.03 16.03 1.0 1710724 TimTec1_006597 O=C(CCCc1ccccc1)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L20 compound treatment 0.441 0.195 10.5 10.495 1.0 1446113 TimTec1_006598 CC(=O)Nc1ccc(Nc2nc(c3ccccc3)c4cc(Br)ccc4n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L21 compound treatment 0.26 0.0143 0.77 0.7685 1.0 1019857 TimTec1_006599 O=C1N(C(C=C1Nc2ccccc2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L22 compound treatment 0.45 0.204 10.98 10.9787 1.0 1376758 TimTec1_006600 O=C(CCNc1ccccc1)n2c(=O)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L23 mock treatment 0.257 0.0113 0.61 0.6072 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 L24 mock treatment 0.231 -0.0147 -0.79 -0.7899 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M01 compound treatment 0.255 0.0093 0.5 0.4998 1.0 3087505 TimTec1_006601 COc1ccc(OCCNC(=O)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M02 compound treatment 0.407 0.161 8.67 8.6679 1.0 3211642 TimTec1_006602 O=C(CSc1nc2ccccc2o1)N3CCNC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M03 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 3211643 TimTec1_006603 CCNS(=O)(=O)c1ccc(OC)c2ncccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M04 compound treatment 0.269 0.0233 1.25 1.2521 1.0 3087508 TimTec1_006604 CCOC(=O)c1c(C)n(N2C(=O)CSC2=S)c(C)c1C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M05 compound treatment 0.253 0.0073 0.39 0.3923 1.0 1629022 TimTec1_006605 COc1ccc2cnn(c3ccccc3)c(=O)c2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M06 compound treatment 0.408 0.162 8.72 8.7217 1.0 3087510 TimTec1_006606 C1CCN(CC1)c2ccc(nn2)n3ccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M07 compound treatment 0.251 0.0053 0.28 0.2848 1.0 3211644 TimTec1_006607 CCC1(CC)C(OC(=O)C(C)(C)C1=O)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M08 compound treatment 0.288 0.0423 2.27 2.2731 1.0 3211645 TimTec1_006608 O=C1CC(Cc2nc(NCc3ccccc3)ncc12)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M09 compound treatment 0.276 0.0303 1.63 1.6283 1.0 1747097 TimTec1_006609 CC(=O)Oc1ccc(c(OC(=O)C)c1)C2(CCCC23)Oc4cc(OC(=O)C)ccc4C53CCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M10 compound treatment 0.265 0.0193 1.04 1.0371 1.0 3088015 TimTec1_006610 Fc1ccc(COc2ccccc2CNC3CCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M11 compound treatment 0.252 0.0063 0.34 0.3385 1.0 3088017 TimTec1_006611 OC(=O)CC(c1ccccc1)n2cnnn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M12 compound treatment 0.465 0.219 11.78 11.7847 1.0 1301285 TimTec1_006612 COc1ccc2oc(=O)c(cc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M13 compound treatment 0.286 0.0403 2.17 2.1656 1.0 3211646 TimTec1_006613 CCOC(=O)COc1ccc(cc1)c2nnn[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M14 compound treatment 0.312 0.0663 3.56 3.5628 1.0 3088019 TimTec1_006614 COc1ccc2oc(=O)cc(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M15 compound treatment 0.252 0.0063 0.34 0.3385 1.0 1315478 TimTec1_006615 CCN(C(=S)Nc1cccnc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M16 compound treatment 0.386 0.14 7.54 7.5394 1.0 3088021 TimTec1_006616 COc1ccc2c(=O)c(coc2c1)c3ccc(OC)c(OC)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M17 compound treatment 0.276 0.0303 1.63 1.6283 1.0 3211647 TimTec1_006617 CCCCS(=O)(=O)c1c(O)nc2ccc(Cl)cc2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M18 compound treatment 0.503 0.257 13.83 13.8268 1.0 3088023 TimTec1_006618 COc1ccc(cc1)c2cc(=O)c3cccc(C)c3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M19 compound treatment 0.306 0.0603 3.24 3.2404 1.0 3211648 TimTec1_006619 CC1(C)CC(=O)C2=C(C1)Nc3cc4OCOc4cc3C2c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M20 compound treatment 0.269 0.0233 1.25 1.2521 1.0 3088025 TimTec1_006620 CC(Sc1ccccc1)C(=O)Nc2ccc(CC#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M21 compound treatment 0.27 0.0243 1.31 1.3058 1.0 1664070 TimTec1_006621 CCC(C)c1ccccc1NC(=S)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M22 compound treatment 0.292 0.0463 2.49 2.4881 1.0 1204548 TimTec1_006622 COc1cccc(c1)C(CC(=O)Nc2cccc3ccccc23)NC(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M23 mock treatment 0.367 0.121 6.52 6.5184 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 M24 mock treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N01 compound treatment 0.26 0.0143 0.77 0.7685 1.0 3211649 TimTec1_006623 CCc1c(C)n[n+]2cnn(Cc3ccccc3)c2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N02 compound treatment 0.323 0.0773 4.15 4.1539 1.0 1159257 TimTec1_006624 O=C(CC(c1ccccc1)c2ccccc2)NCC3COc4ccccc4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N03 compound treatment 0.264 0.0183 0.98 0.9834 1.0 1523675 TimTec1_006625 CC(C)C1C(N(C)C(CC1(O)c2ccccc2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N04 compound treatment 0.253 0.0073 0.39 0.3923 1.0 1565133 TimTec1_006626 OC(=O)C1C(C(C1c2ccccc2)C(=O)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N05 compound treatment 0.529 0.283 15.22 15.2239 1.0 3088098 TimTec1_006627 FC(F)(F)C(=O)Nc1cccc(c1)C(=O)OCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N06 compound treatment 0.324 0.0783 4.21 4.2077 1.0 1325486 TimTec1_006628 O=C(Nc1cc2cc[nH]c2cn1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N07 compound treatment 0.338 0.0923 4.96 4.96 1.0 1651914 TimTec1_006629 Cc1nc2c(Cl)cccc2c(O)c1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N08 compound treatment 0.328 0.0823 4.42 4.4226 1.0 1624701 TimTec1_006630 Nc1cc(nn1Cc2ccc(Cl)cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N09 compound treatment 0.263 0.0173 0.93 0.9297 1.0 3211650 TimTec1_006631 Cc1ccc(cc1)S(=O)(=O)C2CS(=O)(=O)CC2S(=O)(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N10 compound treatment 0.258 0.0123 0.66 0.661 1.0 1719238 TimTec1_006632 OC(=O)c1cnc2ccc(F)cc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N11 compound treatment 0.265 0.0193 1.04 1.0371 1.0 1420410 TimTec1_006633 O=C(Cc1ccccc1)NCC2(CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N12 compound treatment 0.492 0.246 13.24 13.2356 1.0 3211651 TimTec1_006634 CCN(CC)C(=O)COc1cc(C)c(Cl)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N13 compound treatment 0.276 0.0303 1.63 1.6283 1.0 1106512 TimTec1_006635 Nc1nc(nc2sc3CCCCc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N14 compound treatment 0.481 0.235 12.64 12.6445 1.0 3211652 TimTec1_006636 Cc1ccc(Sc2c(nc3ncccn23)c4ccccc4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N15 compound treatment 0.278 0.0323 1.74 1.7357 1.0 1300777 TimTec1_006637 CC1=CCC(NC1c2ccccc2)c3cnc(c(C)c3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N16 compound treatment 0.253 0.0073 0.39 0.3923 1.0 3211653 TimTec1_006638 COc1cccc(CNCCc2ccccc2)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N17 compound treatment 0.386 0.14 7.54 7.5394 1.0 1725536 TimTec1_006639 CC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3F)Nc4ccccc14)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N18 compound treatment 0.297 0.0513 2.76 2.7568 1.0 1400907 TimTec1_006640 CCOC(=O)Cc1csc(NCC=C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N19 compound treatment 0.354 0.108 5.82 5.8198 1.0 1270718 TimTec1_006641 CCOc1cccc(NC(=O)CC#N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N20 compound treatment 0.253 0.0073 0.39 0.3923 1.0 1455920 TimTec1_006642 CC1CC(=O)C(C)CN1CCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N21 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 3211654 TimTec1_006643 O=C1O/C(=C/C=C\2/OC(=O)c3ccccc23)/c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N22 compound treatment 0.25 0.0043 0.23 0.2311 1.0 1354629 TimTec1_006644 Fc1ccccc1C(=O)N2c3ccccc3Sc4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N23 mock treatment 0.254 0.0083 0.45 0.446 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 N24 mock treatment 0.232 -0.0137 -0.74 -0.7362 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O01 compound treatment 0.289 0.0433 2.33 2.3269 1.0 3211758 TimTec1_006645 O=C(NCCOc1ccccc1Cc2ccccc2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O02 compound treatment 0.267 0.0213 1.14 1.1446 1.0 3088109 TimTec1_006646 CC(=O)Nc1nonc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O03 compound treatment 0.25 0.0043 0.23 0.2311 1.0 3211759 TimTec1_006647 CN(C(=O)c1c(C)c(Cl)c(C)nc1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O04 compound treatment 0.451 0.205 11.03 11.0324 1.0 3088110 TimTec1_006648 N=C1C(=C(N2CCOCC2)c3cc4CCCCc4n13)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O05 compound treatment 0.299 0.0533 2.86 2.8642 1.0 3088179 TimTec1_006649 CCOC(=O)c1ccc(NC2Nc3cc(C)nn3S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O06 compound treatment 0.301 0.0553 2.97 2.9717 1.0 3088181 TimTec1_006650 Fc1ccc(Nc2nc3ccccc3o2)c(F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O07 compound treatment 0.258 0.0123 0.66 0.661 1.0 3088183 TimTec1_006651 CCn1c(=O)c(cc2cc(Cl)ccc12)c3ccc4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O08 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 3211760 TimTec1_006652 COC(=O)CC1N(CCNC1=O)C(=O)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O09 compound treatment 0.444 0.198 10.66 10.6562 1.0 3211761 TimTec1_006653 CCC(Sc1nc(=O)cc(N)n1CCc2ccccc2)C(=O)Nc3nc(cs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O10 compound treatment 0.261 0.0153 0.82 0.8222 1.0 3088185 TimTec1_006654 CSc1nnc(s1)N2C(=O)CC(C3=C2CCCC3=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O11 compound treatment 0.265 0.0193 1.04 1.0371 1.0 3211762 TimTec1_006655 C1CC(CCN1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O12 compound treatment 0.445 0.199 10.71 10.71 1.0 1188337 TimTec1_006656 COc1ccc2cc(C#N)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O13 compound treatment 0.311 0.0653 3.51 3.5091 1.0 3211763 TimTec1_006657 COC(=O)/N=c/1\[cH-][n+](no1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O14 compound treatment 0.351 0.105 5.66 5.6586 1.0 3088188 TimTec1_006658 COc1ccc(cc1OC)c2c(C)c3cc(Cl)c(O)cc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O15 compound treatment 0.26 0.0143 0.77 0.7685 1.0 3211764 TimTec1_006659 CC12CCC3C(CC=C4CC(O)CCC34C)C2C/C(=C\c5ccc(F)cc5)/C1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O16 compound treatment 0.258 0.0123 0.66 0.661 1.0 3088190 TimTec1_006660 CC(=O)n1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O17 compound treatment 0.463 0.217 11.68 11.6772 1.0 3211765 TimTec1_006661 CC1(C)CC(C)(c2ccccc2)c3cccc4/C(=C\5/SC(=O)NC5=O)/C(=O)N1c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O18 compound treatment 0.354 0.108 5.82 5.8198 1.0 1529444 TimTec1_006662 O=C(N1CCCC1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O19 compound treatment 0.249 0.0033 0.18 0.1773 1.0 3211766 TimTec1_006663 CCOc1ccc(cc1)C(CC(=O)O)NC(=O)c2c(C)onc2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O20 compound treatment 0.277 0.0313 1.68 1.682 1.0 3088193 TimTec1_006664 CC(Sc1ccccc1)C(=O)Nc2cc(C)cc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O21 compound treatment 0.317 0.0713 3.83 3.8315 1.0 3211767 TimTec1_006665 CCCc1nc(O)c2sc(=S)n(c3ccccc3)c2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O22 compound treatment 0.35 0.104 5.6 5.6049 1.0 1236651 TimTec1_006666 CCc1cc(C(=O)Cc2nc3ccccc3[nH]2)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O23 mock treatment 0.248 0.0023 0.12 0.1236 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 O24 mock treatment 0.25 0.0043 0.23 0.2311 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P01 compound treatment 0.255 0.0093 0.5 0.4998 1.0 1473206 TimTec1_006667 CC1(C)CNC(=O)c2sc(nc2C1)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P02 compound treatment 0.321 0.0753 4.05 4.0465 1.0 1588991 TimTec1_006668 Cc1ccc(c2csc(Nc3ccc(cc3)C(=O)O)n2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P03 compound treatment 0.278 0.0323 1.74 1.7357 1.0 1700904 TimTec1_006669 CCOC(=O)Cc1csc(NC(=O)CC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P04 compound treatment 0.244 -0.0017 -0.09 -0.0914 -1.0 1292116 TimTec1_006670 Brc1ccc(cc1)c2ccc(cn2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P05 compound treatment 0.27 0.0243 1.31 1.3058 1.0 1398485 TimTec1_006671 Cc1ccc(C)c(NCc2ccc3OCOc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P06 compound treatment 0.428 0.182 9.8 9.7964 1.0 1394993 TimTec1_006672 C(Cn1c2nc(cn2c3ccccc13)c4ccccc4)N5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P07 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 1307464 TimTec1_006673 CC(C)C(=O)Nc1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P08 compound treatment 0.318 0.0723 3.89 3.8853 1.0 1718869 TimTec1_006674 CCCC(CCC)C(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P09 compound treatment 0.349 0.103 5.55 5.5511 1.0 3088199 TimTec1_006675 O=C(CSc1ccccc1)N2CCCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P10 compound treatment 0.27 0.0243 1.31 1.3058 1.0 3211768 TimTec1_006676 CC(C)C/1Oc2cc3oc(=O)ccc3cc2\C1=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P11 compound treatment 0.419 0.173 9.31 9.3128 1.0 1289028 TimTec1_006677 CN(C(=O)c1ccccc1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P12 compound treatment 0.242 -0.0037 -0.2 -0.1988 -1.0 1729839 TimTec1_006678 OC(=O)CCCC(=O)Nc1ccccn1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P13 compound treatment 0.266 0.0203 1.09 1.0909 1.0 3088277 TimTec1_006679 COC(=O)C(C)Oc1nc(C)c(Br)c(OC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P14 compound treatment 0.238 -0.0077 -0.41 -0.4138 -1.0 1337521 TimTec1_006680 CCCc1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P15 compound treatment 0.236 -0.0097 -0.52 -0.5213 -1.0 3211769 TimTec1_006681 CC(C)C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P16 compound treatment 0.262 0.0163 0.88 0.8759 1.0 1376316 TimTec1_006682 OC(=O)CCNc1ncnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P17 compound treatment 0.252 0.0063 0.34 0.3385 1.0 3211770 TimTec1_006683 COc1cccc(c1)N2C(=O)CN=C2Nc3nc(C)cc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P18 compound treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 3211771 TimTec1_006684 CCC1CCC2(CC1)NNC(=S)NN2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P19 compound treatment 0.239 -0.0067 -0.36 -0.36 -1.0 1168709 TimTec1_006685 NC(=O)C1CCN(CC1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P20 compound treatment 0.268 0.0223 1.2 1.1984 1.0 1615021 TimTec1_006686 Fc1ccc2[nH]c3C(CCCc3c2c1)NC=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P21 compound treatment 0.435 0.189 10.17 10.1726 1.0 3088282 TimTec1_006687 CCCCc1nnc(NC(=O)CC)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P22 compound treatment 0.241 -0.0047 -0.25 -0.2526 -1.0 1124526 TimTec1_006688 COc1ccc(CCNC2CCCCC2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P23 mock treatment 0.24 -0.0057 -0.31 -0.3063 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2081 P24 mock treatment 0.243 -0.0027 -0.15 -0.1451 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A01 compound treatment 0.268 0.0139 0.75 0.749 1.0 1191118 TimTec1_006689 COCC(C)NCc1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A02 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1573567 TimTec1_006690 O=S(=O)(N1CCOCC1)c2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A03 compound treatment 0.238 -0.0161 -0.86 -0.8632 -1.0 1587133 TimTec1_006691 CC(C)OC(=O)C1=C(C)N(C)C(=O)NC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A04 compound treatment 0.239 -0.0151 -0.81 -0.8094 -1.0 1537360 TimTec1_006692 OCCN1C(=O)CSC21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A05 compound treatment 0.234 -0.0201 -1.08 -1.0781 -1.0 3088287 TimTec1_006693 OC(=O)CC1NC(=NC1=O)Nc2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A06 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 3211772 TimTec1_006694 C(Sc1ncnc2sc3CCCCc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A07 compound treatment 0.223 -0.0311 -1.67 -1.6692 -1.0 1192303 TimTec1_006695 OC(=O)CC1=C(CCC1=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A08 compound treatment 0.232 -0.0221 -1.19 -1.1856 -1.0 1579568 TimTec1_006696 CC(C)N1CCN(Cc2ccc(F)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A09 compound treatment 0.236 -0.0181 -0.97 -0.9706 -1.0 3211773 TimTec1_006697 CCCC(=O)Nc1ccccc1OC(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A10 compound treatment 0.285 0.0309 1.66 1.6625 1.0 3088290 TimTec1_006698 FC(F)(F)c1cccc(NC(=S)NC(=O)c2ccccc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A11 compound treatment 0.336 0.0819 4.4 4.4031 1.0 1555167 TimTec1_006699 Clc1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A12 compound treatment 0.229 -0.0251 -1.35 -1.3468 -1.0 1739061 TimTec1_006700 Cc1nc2ccccc2c(O)c1CN(CC=C)CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A13 compound treatment 0.224 -0.0301 -1.62 -1.6155 -1.0 1541571 TimTec1_006701 COC(=O)C(CC(C)C)NC(=O)c1ccco1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A14 compound treatment 0.365 0.111 5.96 5.9615 1.0 1353905 TimTec1_006702 COc1ccc(cc1OC)C2(CCc3[nH]c4ccccc4c3C2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A15 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1788321 TimTec1_006703 Nc1ccc2[nH]c(Cc3ccccc3)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A16 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1538142 TimTec1_006704 CC(=O)Nc1ccc(cc1)S(=O)(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A17 compound treatment 0.24 -0.0141 -0.76 -0.7557 -1.0 3088294 TimTec1_006705 Brc1ccc(cc1)C(=O)COC(=O)c2cn(nc2c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A18 compound treatment 0.259 0.00494 0.27 0.2653 1.0 1281666 TimTec1_006706 CC(C)(C)C(=O)Cn1c(NCCO)nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A19 compound treatment 0.335 0.0809 4.35 4.3494 1.0 1640157 TimTec1_006707 CCOc1ccc(cc1)C(=O)OCCC2CCCN3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A20 compound treatment 0.286 0.0319 1.72 1.7163 1.0 1913968 TimTec1_006708 Clc1ccc(NCn2nnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A21 compound treatment 0.347 0.0929 4.99 4.9943 1.0 1634555 TimTec1_006709 Cc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A22 compound treatment 0.39 0.136 7.3 7.305 1.0 1298020 TimTec1_006710 CC1=CCC(C(C1)C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A23 mock treatment 0.266 0.0119 0.64 0.6415 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 A24 mock treatment 0.273 0.0189 1.02 1.0177 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B01 compound treatment 0.24 -0.0141 -0.76 -0.7557 -1.0 1702916 TimTec1_006711 CCC(=O)Nc1sc(C(=O)N2CCCCC2)c(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B02 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 3211774 TimTec1_006712 Cc1ccccc1CNCCc2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B03 compound treatment 0.276 0.0219 1.18 1.1789 1.0 1742610 TimTec1_006713 Cc1c(Cl)cccc1NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B04 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1433621 TimTec1_006714 CN(C)c1nc2c(N)ncnc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B05 compound treatment 0.289 0.0349 1.88 1.8775 1.0 3211866 TimTec1_006715 O=S(=O)(CCC#N)c1ccc(Oc2ccc(cc2)S(=O)(=O)CCC#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B06 compound treatment 0.294 0.0399 2.15 2.1462 1.0 3088376 TimTec1_006716 CC(Sc1ccccc1)C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B07 compound treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1180218 TimTec1_006717 OC(=O)c1cc2c(ccc3ccccc32)oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B08 compound treatment 0.245 -0.00906 -0.49 -0.487 -1.0 3088379 TimTec1_006718 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N2CCN=C2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B09 compound treatment 0.267 0.0129 0.7 0.6952 1.0 1330797 TimTec1_006719 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B10 compound treatment 0.245 -0.00906 -0.49 -0.487 -1.0 3211867 TimTec1_006720 O/N=C/1\CCCc2c1nc(c3ccccc3Cl)n2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B11 compound treatment 0.227 -0.0271 -1.45 -1.4543 -1.0 1713095 TimTec1_006721 CNC(=O)CC1Nc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B12 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 1487671 TimTec1_006722 Cc1ccc(C)c(NC(=O)c2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B13 compound treatment 0.239 -0.0151 -0.81 -0.8094 -1.0 1579293 TimTec1_006723 CCC(C)N1CCN(CC2CCC=CC2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B14 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 3211868 TimTec1_006724 FC(F)(F)c1nn(CC(=O)N2CCCc3ccccc23)c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B15 compound treatment 0.224 -0.0301 -1.62 -1.6155 -1.0 3088384 TimTec1_006725 O/N=C/1\CCC2CN(CC2C1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B16 compound treatment 0.366 0.112 6.02 6.0153 1.0 3211869 TimTec1_006726 CCOC(=O)CSc1ncnc2sc(C)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B17 compound treatment 0.434 0.18 9.67 9.6695 1.0 1621335 TimTec1_006727 Cc1cc(SCC(=O)Nc2ccccc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B18 compound treatment 0.265 0.0109 0.59 0.5878 1.0 3088387 TimTec1_006728 CSC1=C(C#N)C(CC(=O)N1)c2ccc(cc2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B19 compound treatment 0.28 0.0259 1.39 1.3938 1.0 1235770 TimTec1_006729 NC(=O)C1CCN(CCC(=O)Nc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B20 compound treatment 0.281 0.0269 1.45 1.4476 1.0 1483335 TimTec1_006730 COc1ccc(NC(=O)CC2(Cc3ccccc3)CCOC(C)(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B21 compound treatment 0.24 -0.0141 -0.76 -0.7557 -1.0 1160668 TimTec1_006731 CC(C)C1(CN2CC3CN(C1)CC2)C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B22 compound treatment 0.282 0.0279 1.5 1.5013 1.0 1622689 TimTec1_006732 COc1ccc2NC(C3CC=CC3c2c1)c4cc5OCOc5cc4Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B23 mock treatment 0.265 0.0109 0.59 0.5878 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 B24 mock treatment 0.243 -0.0111 -0.59 -0.5945 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C01 compound treatment 0.401 0.147 7.9 7.8961 1.0 1335975 TimTec1_006733 C(CN1CCOCC1)Cn2c(cn3c2nc4ccccc43)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C02 compound treatment 0.387 0.133 7.14 7.1438 1.0 1454078 TimTec1_006734 COC(=O)c1ccc(cc1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C03 compound treatment 0.259 0.00494 0.27 0.2653 1.0 1235834 TimTec1_006735 COc1cccc(CN2CCN(CC2)C(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C04 compound treatment 0.245 -0.00906 -0.49 -0.487 -1.0 1253454 TimTec1_006736 Cc1ccc(O)c(CCc2ccc(O)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C05 compound treatment 0.336 0.0819 4.4 4.4031 1.0 3211870 TimTec1_006737 CN(Cc1ccccc1)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(C)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C06 compound treatment 0.245 -0.00906 -0.49 -0.487 -1.0 1784507 TimTec1_006738 [O-][n+]1c2CCc3nonc3-c2nn1c4ccccc4Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C07 compound treatment 0.42 0.166 8.92 8.9171 1.0 1708265 TimTec1_006739 Clc1ccc(cc1)C(=O)NCC2(CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C08 compound treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1294485 TimTec1_006740 COC(=O)c1sc2nc(cc(c3ccccc3)c2c1N)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C09 compound treatment 0.261 0.00694 0.37 0.3728 1.0 1189050 TimTec1_006741 Brc1cc(Br)c2oc(=O)c(cc2c1)C(=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C10 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1225819 TimTec1_006742 Brc1ccc(cc1)C(=O)Oc2ccc3oc(=O)sc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C11 compound treatment 0.291 0.0369 1.98 1.9849 1.0 3211871 TimTec1_006743 OC(=O)c1cc(nc2ccc(Br)cc12)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C12 compound treatment 0.359 0.105 5.64 5.6391 1.0 1285755 TimTec1_006744 OC(=O)c1ccc(Nc2nc(cs2)c3ccc(Cl)c(Cl)c3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C13 compound treatment 0.273 0.0189 1.02 1.0177 1.0 1580452 TimTec1_006745 O(c1ccccc1)c2nnc(c3ccccc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C14 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1550487 TimTec1_006746 CC(=O)N1CC(C=C(C)C1c2ccccc2)c3cnc(c(C)c3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C15 compound treatment 0.312 0.0579 3.11 3.1134 1.0 1546076 TimTec1_006747 COc1ccc2n(C)c(C)c(C(=O)CSc3ccccc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C16 compound treatment 0.241 -0.0131 -0.7 -0.702 -1.0 3211872 TimTec1_006748 COc1ccc(CNCCC2(Cc3ccccc3)CC(C)N(C)CC2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C17 compound treatment 0.507 0.253 13.59 13.5923 1.0 3088471 TimTec1_006749 N#Cc1c(SCc2ccccc2C#N)nsc1SCc3ccccc3C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C18 compound treatment 0.234 -0.0201 -1.08 -1.0781 -1.0 1128012 TimTec1_006750 CC(C)CC(=O)NC(c1ccccc1)c2c(O)ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C19 compound treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 1522229 TimTec1_006751 COc1ccccc1C2C3=C(CCCC3=O)N(CC(=O)O)C4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C20 compound treatment 0.273 0.0189 1.02 1.0177 1.0 3211873 TimTec1_006752 CC(C)NC(=O)CSCc1ccc(Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C21 compound treatment 0.294 0.0399 2.15 2.1462 1.0 1278138 TimTec1_006753 NC(=O)c1cc(N)ccc1N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C22 compound treatment 0.263 0.00894 0.48 0.4803 1.0 1148287 TimTec1_006754 CC(C)C1=CC2=C(CC(C)(C)CC2=O)OC1N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C23 mock treatment 0.264 0.00994 0.53 0.534 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 C24 mock treatment 0.253 -0.00106 -0.06 -0.0571 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D01 compound treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1357090 TimTec1_006755 Cc1ccc2n3CCN(CC#N)C4CCc(c43)c(=O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D02 compound treatment 0.286 0.0319 1.72 1.7163 1.0 3088476 TimTec1_006756 COc1ccc(cc1OC)c2cc(nc(N)c2C#N)c3ccc(Cl)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D03 compound treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1669245 TimTec1_006757 C(C#Cc1ccccc1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D04 compound treatment 0.376 0.122 6.55 6.5527 1.0 1279830 TimTec1_006758 O=c1cc(N2CCCC2)c3ccccc3o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D05 compound treatment 0.275 0.0209 1.13 1.1251 1.0 3211874 TimTec1_006759 O=C1C(C(=O)c2ccccc12)c3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D06 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1228770 TimTec1_006760 Fc1ccc(cc1)C(CCCN2CCN3CCCCCC3C2)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D07 compound treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1294456 TimTec1_006761 OC(=O)c1ccccc1C(=O)N(Cc2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D08 compound treatment 0.302 0.0479 2.58 2.5761 1.0 1150523 TimTec1_006762 O=C1CC(CC2=C1C(Nc3ccccc3N2)c4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D09 compound treatment 0.23 -0.0241 -1.29 -1.2931 -1.0 3088554 TimTec1_006763 COc1ccc2c(c(C)oc2c1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D10 compound treatment 0.273 0.0189 1.02 1.0177 1.0 3088557 TimTec1_006764 CC(=O)Nc1ccc2n(C)c(C)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D11 compound treatment 0.248 -0.00606 -0.33 -0.3258 -1.0 1170616 TimTec1_006765 Cc1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D12 compound treatment 0.287 0.0329 1.77 1.77 1.0 1215173 TimTec1_006766 COc1ccccc1NC(=O)C2=C(C)NC3=C(C2c4ccc(Cl)cc4Cl)C(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D13 compound treatment 0.357 0.103 5.53 5.5316 1.0 1235033 TimTec1_006767 Cc1c(oc2ccccc12)C(=O)OCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D14 compound treatment 0.227 -0.0271 -1.45 -1.4543 -1.0 1338758 TimTec1_006768 CC(C)Oc1ccc(CNC2CCOC(C)(C)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D15 compound treatment 0.263 0.00894 0.48 0.4803 1.0 3211875 TimTec1_006769 CCCOc1nc(cc(n1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D16 compound treatment 0.39 0.136 7.3 7.305 1.0 3211876 TimTec1_006770 Cc1sc2ncnc(SCC(=O)Nc3cc(C)ccc3C)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D17 compound treatment 0.38 0.126 6.77 6.7676 1.0 1122485 TimTec1_006771 Cc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCCN5CCCCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D18 compound treatment 0.269 0.0149 0.8 0.8027 1.0 1249464 TimTec1_006772 COC(=O)c1ccc(cc1)C2Nc3c(cccc3C4C=CCC42)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D19 compound treatment 0.256 0.00194 0.1 0.1041 1.0 1389916 TimTec1_006773 CC1CCN(CCC(=O)Nc2ccc3OCOc3c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D20 compound treatment 0.371 0.117 6.28 6.284 1.0 1429288 TimTec1_006774 CC(C)c1ccc(OCC(=O)NC(C)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D21 compound treatment 0.271 0.0169 0.91 0.9102 1.0 1645937 TimTec1_006775 COc1cc(ccc1O)C(C#N)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D22 compound treatment 0.379 0.125 6.71 6.7139 1.0 3088562 TimTec1_006776 COc1ccc(Cl)cc1C(=O)CSc2cc(C)c3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D23 mock treatment 0.251 -0.00306 -0.16 -0.1646 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 D24 mock treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E01 compound treatment 0.245 -0.00906 -0.49 -0.487 -1.0 1193138 TimTec1_006777 COC(=O)c1cc(CN2CCN(C)CC2)ccc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E02 compound treatment 0.266 0.0119 0.64 0.6415 1.0 1776719 TimTec1_006778 Oc1[nH]c(=O)c(C#N)c2CCN(Cc3ccccc3)Cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E03 compound treatment 0.308 0.0539 2.9 2.8985 1.0 1574650 TimTec1_006779 CC(C)CNC(=O)c1cccc(NC(=O)c2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E04 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1646030 TimTec1_006780 CC(Nc1ncnc2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E05 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1655517 TimTec1_006781 CCCCC1(CC(C)(OC1=O)c2csc(N)n2)C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E06 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1315927 TimTec1_006782 CN1CCCC(C1)OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E07 compound treatment 0.268 0.0139 0.75 0.749 1.0 1216871 TimTec1_006783 CCCN(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E08 compound treatment 0.24 -0.0141 -0.76 -0.7557 -1.0 1623058 TimTec1_006784 COc1ccc(Cl)cc1Nc2nc3cc(C)ccc3cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E09 compound treatment 0.249 -0.00506 -0.27 -0.272 -1.0 3211956 TimTec1_006785 OC(=O)C1CC=CCC1C(=O)Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E10 compound treatment 0.301 0.0469 2.52 2.5223 1.0 1216589 TimTec1_006786 COc1ccc(cc1)N(C=O)C(C(=O)Nc2c(C)cccc2C)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E11 compound treatment 0.242 -0.0121 -0.65 -0.6482 -1.0 1547982 TimTec1_006787 C=CCC1(CCCCC1)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E12 compound treatment 0.273 0.0189 1.02 1.0177 1.0 1164189 TimTec1_006788 Cc1nc(N)nc(O)c1Oc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E13 compound treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1614806 TimTec1_006789 CCC1(C)CC(CC(=O)OC(C)CN(C)C)(CCO1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E14 compound treatment 0.282 0.0279 1.5 1.5013 1.0 1071490 TimTec1_006790 COc1ccc(CCNC(=O)C(c2ccccc2)c3ccccc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E15 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1306668 TimTec1_006791 COc1ccc(C)cc1NCc2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E16 compound treatment 0.516 0.262 14.08 14.076 1.0 1737928 TimTec1_006792 CCc1cc(C(=O)Cc2nc3ccccc3s2)c(O)cc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E17 compound treatment 0.274 0.0199 1.07 1.0714 1.0 1514112 TimTec1_006793 Clc1ccccc1CNC(=O)C2(CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E18 compound treatment 0.276 0.0219 1.18 1.1789 1.0 3088573 TimTec1_006794 CNCC(O)Cn1c2CCCCc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E19 compound treatment 0.342 0.0879 4.73 4.7256 1.0 1478401 TimTec1_006795 CCCC(=O)Nc1sc(C(=O)Nc2cccc(C)c2C)c(C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E20 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1241738 TimTec1_006796 COc1ccc(CCNC(=O)C(C)(C)C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E21 compound treatment 0.259 0.00494 0.27 0.2653 1.0 3087516 TimTec1_006797 CC(=O)Nc1c(O)nc(SCC(=O)N2CCOCC2)nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E22 compound treatment 0.267 0.0129 0.7 0.6952 1.0 1605940 TimTec1_006798 S=C(NCC1CCCO1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E23 mock treatment 0.267 0.0129 0.7 0.6952 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 E24 mock treatment 0.256 0.00194 0.1 0.1041 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F01 compound treatment 0.321 0.0669 3.6 3.5971 1.0 1786318 TimTec1_006799 Cc1ccc(SCC(=O)Nc2cccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F02 compound treatment 0.268 0.0139 0.75 0.749 1.0 3087518 TimTec1_006800 Cc1ccc2nc(Nc3cccc(c3)C(F)(F)F)c(C#N)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F03 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1787075 TimTec1_006801 O=C(OCCN1CCOCC1)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F04 compound treatment 0.484 0.23 12.36 12.3564 1.0 3211957 TimTec1_006802 Cc1ccc(cc1)S(=O)(=O)C(CC(=O)c2ccco2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F05 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 3087520 TimTec1_006803 COc1nc(nc2ccccc12)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F06 compound treatment 0.347 0.0929 4.99 4.9943 1.0 1271720 TimTec1_006804 Cc1ccccc1OCc2nnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F07 compound treatment 0.237 -0.0171 -0.92 -0.9169 -1.0 1606230 TimTec1_006805 Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F08 compound treatment 0.25 -0.00406 -0.22 -0.2183 -1.0 1628397 TimTec1_006806 Cn1c(SCC(=O)NC2CCCCC2)nc3n(C)c(=O)n(C)c(=O)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F09 compound treatment 0.492 0.238 12.79 12.7863 1.0 1514196 TimTec1_006807 OC(=O)c1cccc(NC(=O)c2cc3ccccc3o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F10 compound treatment 0.298 0.0439 2.36 2.3611 1.0 1327645 TimTec1_006808 Nc1cccc(c1)C(=O)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F11 compound treatment 0.235 -0.0191 -1.02 -1.0244 -1.0 1408003 TimTec1_006809 CC(CC(=O)O)n1nnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F12 compound treatment 0.241 -0.0131 -0.7 -0.702 -1.0 3211958 TimTec1_006810 NC(=O)Cn1nc(c2CCCCc21)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F13 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1545556 TimTec1_006811 CNCC(O)CN1CCN(CC1)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F14 compound treatment 0.25 -0.00406 -0.22 -0.2183 -1.0 1280870 TimTec1_006812 O=S1OCC(COc2cccc3ccccc23)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F15 compound treatment 0.375 0.121 6.5 6.4989 1.0 3087526 TimTec1_006813 CCc1ccc(nc1)c2ccc(Br)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F16 compound treatment 0.469 0.215 11.55 11.5503 1.0 1386778 TimTec1_006814 COc1cc(ccc1OCC(=O)Nc2ccccc2C)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F17 compound treatment 0.248 -0.00606 -0.33 -0.3258 -1.0 1919073 TimTec1_006815 CC(C)(C)S(=O)(=O)c1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F18 compound treatment 0.313 0.0589 3.17 3.1672 1.0 1656061 TimTec1_006816 COc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F19 compound treatment 0.276 0.0219 1.18 1.1789 1.0 1199433 TimTec1_006817 Cc1ccc2n3CCN(CC(O)CN4CCCC4)C5CCCc(c53)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F20 compound treatment 0.402 0.148 7.95 7.9499 1.0 1221052 TimTec1_006818 Oc1ccc(NC(=O)c2c(O)c3ccccc3[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F21 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1475350 TimTec1_006819 CCN1N=C(CCC1=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F22 compound treatment 0.387 0.133 7.14 7.1438 1.0 1392419 TimTec1_006820 Cc1ccc(OCC(=O)N2CCN(CC3CC4CC3C=C4)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F23 mock treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 F24 mock treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G01 compound treatment 0.258 0.00394 0.21 0.2116 1.0 1567385 TimTec1_006821 COc1ccc(CNc2cc(C)cc(C)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G02 compound treatment 0.241 -0.0131 -0.7 -0.702 -1.0 3087531 TimTec1_006822 CC1CC2(CCCCC2)N(C(=O)C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G03 compound treatment 0.34 0.0859 4.62 4.6181 1.0 3211959 TimTec1_006823 Cc1sc2ncnc(SCc3ccc(C)cc3)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G04 compound treatment 0.294 0.0399 2.15 2.1462 1.0 1130050 TimTec1_006824 CCC(C)OC(=O)C1=C(C)NC2=C(C1c3ccc(C)o3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G05 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1376669 TimTec1_006825 CC(Cc1ccccc1)NC(=O)C2CCCNC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G06 compound treatment 0.237 -0.0171 -0.92 -0.9169 -1.0 1285783 TimTec1_006826 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccccc3O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G07 compound treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1630547 TimTec1_006827 OCC(NC(=O)c1cncc(O)c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G08 compound treatment 0.293 0.0389 2.09 2.0924 1.0 1290578 TimTec1_006828 NC1=C(C#N)C2(CCCCC2)C(=C(N1)SCc3ccccc3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G09 compound treatment 0.397 0.143 7.68 7.6812 1.0 1492451 TimTec1_006829 O=C(CN(C1CCCCC1)C(=O)c2ccccc2)Nc3nc(cs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G10 compound treatment 0.24 -0.0141 -0.76 -0.7557 -1.0 1506265 TimTec1_006830 CC(CN1CCCCC1)OC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G11 compound treatment 0.283 0.0289 1.56 1.555 1.0 1676645 TimTec1_006831 Clc1cccc(CN2CCN(CC2)C(=O)c3cccs3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G12 compound treatment 0.271 0.0169 0.91 0.9102 1.0 1179682 TimTec1_006832 CCOc1ccc2nc3CCCCc3c(C(=O)O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G13 compound treatment 0.579 0.325 17.46 17.4615 1.0 3212025 TimTec1_006833 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccccc3Br)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G14 compound treatment 0.282 0.0279 1.5 1.5013 1.0 1719128 TimTec1_006834 CCCCC1CN2CCc3c([nH]c4ccccc34)C2(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G15 compound treatment 0.282 0.0279 1.5 1.5013 1.0 1540479 TimTec1_006835 CNC(=O)c1c(O)c2ccccc2n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G16 compound treatment 0.273 0.0189 1.02 1.0177 1.0 3087554 TimTec1_006836 CC(C)C(=O)Nc1cccc2nsnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G17 compound treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 1681031 TimTec1_006837 CCC(C)N1CCN(CC1)C(=O)C(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G18 compound treatment 0.321 0.0669 3.6 3.5971 1.0 1312686 TimTec1_006838 CCOC(=O)c1sc(nc1C)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)c(C)c3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G19 compound treatment 0.262 0.00794 0.43 0.4265 1.0 3087555 TimTec1_006839 CC(=O)n1c(=O)n(C(=O)C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G20 compound treatment 0.266 0.0119 0.64 0.6415 1.0 3212026 TimTec1_006840 COc1ccc(CNCCC2(CCOC(C)(C)C2)c3ccccc3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G21 compound treatment 0.256 0.00194 0.1 0.1041 1.0 1426762 TimTec1_006841 CC(=C)CNCC1OCCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G22 compound treatment 0.291 0.0369 1.98 1.9849 1.0 1432528 TimTec1_006842 Fc1ccccc1C(=O)N2CCC(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G23 mock treatment 0.25 -0.00406 -0.22 -0.2183 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 G24 mock treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H01 compound treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 1714695 TimTec1_006843 Nc1nncn1C(=O)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H02 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 3087557 TimTec1_006844 Cc1sc(NC(=O)c2cccc(C)c2)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H03 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1542138 TimTec1_006845 OC(=O)CC(NC(=O)c1ccccc1Cl)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H04 compound treatment 0.302 0.0479 2.58 2.5761 1.0 1720177 TimTec1_006846 Brc1ccc(o1)C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H05 compound treatment 0.258 0.00394 0.21 0.2116 1.0 1733502 TimTec1_006847 COc1ccccc1NC(=O)Cc2csc(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H06 compound treatment 0.361 0.107 5.75 5.7466 1.0 1681208 TimTec1_006848 O=C1OC2(C3CCCC2C31Sc4ccccc4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H07 compound treatment 0.253 -0.00106 -0.06 -0.0571 -1.0 1675342 TimTec1_006849 CC1(C)Cc2c(CO1)sc3c2c(=O)n(Cc4ccccc4)c5nncn53 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H08 compound treatment 0.284 0.0299 1.61 1.6088 1.0 3212027 TimTec1_006850 CC(C)CCn1c(nc2ccccc12)C(C)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H09 compound treatment 0.289 0.0349 1.88 1.8775 1.0 1775014 TimTec1_006851 Oc1c(C(=O)NCCN2CCOCC2)c(=O)[nH]c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H10 compound treatment 0.369 0.115 6.18 6.1765 1.0 1635890 TimTec1_006852 CCCCC(=O)Nc1sc2CCCCc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H11 compound treatment 0.317 0.0629 3.38 3.3821 1.0 3087563 TimTec1_006853 OC(=O)c1ccc(CSCc2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H12 compound treatment 0.442 0.188 10.1 10.0994 1.0 3212028 TimTec1_006854 C(Cc1nc2ccccc2s1)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H13 compound treatment 0.267 0.0129 0.7 0.6952 1.0 1288163 TimTec1_006855 CCc1nc(NCc2ccccc2)c(C#N)c3CC(C)(C)OCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H14 compound treatment 0.404 0.15 8.06 8.0573 1.0 1574023 TimTec1_006856 O=C(CSCc1ccccc1)Nc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H15 compound treatment 0.265 0.0109 0.59 0.5878 1.0 1780586 TimTec1_006857 COc1ccc(cc1OC)/C(=C/N2CCOCC2)/C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H16 compound treatment 0.334 0.0799 4.3 4.2957 1.0 1294188 TimTec1_006858 CCOC(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2OC)c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H17 compound treatment 0.399 0.145 7.79 7.7886 1.0 1244483 TimTec1_006859 O=C(Nc1ccccn1)c2cccc(c2)C(=O)Nc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H18 compound treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 1620067 TimTec1_006860 OC(=O)CSCC(=O)N(c1ccccc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H19 compound treatment 0.442 0.188 10.1 10.0994 1.0 3212030 TimTec1_006861 CN(C)c1ccc(cc1)C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H20 compound treatment 0.242 -0.0121 -0.65 -0.6482 -1.0 1410666 TimTec1_006862 CC(C)N1CCN(CC1)C(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H21 compound treatment 0.257 0.00294 0.16 0.1579 1.0 3087568 TimTec1_006863 COC(=O)c1ccc(C(=O)OC)c2c(ccc(C(=O)OC)c12)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H22 compound treatment 0.288 0.0339 1.82 1.8237 1.0 1331832 TimTec1_006864 O=C(Cc1ccccc1)N2CCN(CCCc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H23 mock treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 H24 mock treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I01 compound treatment 0.228 -0.0261 -1.4 -1.4005 -1.0 1174741 TimTec1_006865 Brc1ccc(cc1)C(=O)N(C2CCCCC2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I02 compound treatment 0.235 -0.0191 -1.02 -1.0244 -1.0 3087571 TimTec1_006866 COC(=O)C(N)CSC1CCCCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I03 compound treatment 0.299 0.0449 2.41 2.4148 1.0 3212031 TimTec1_006867 COC(=O)c1ccccc1NC(=O)CSc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I04 compound treatment 0.241 -0.0131 -0.7 -0.702 -1.0 1545093 TimTec1_006868 CCC(Sc1nc2ccccc2n1CC)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I05 compound treatment 0.258 0.00394 0.21 0.2116 1.0 1715211 TimTec1_006869 COc1ccc2[nH]c3c(=O)[nH]cnc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I06 compound treatment 0.258 0.00394 0.21 0.2116 1.0 3087574 TimTec1_006870 Cc1c(csc1c2ccccc2)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I07 compound treatment 0.256 0.00194 0.1 0.1041 1.0 1913865 TimTec1_006871 c1c(nn(c1c2ccccc2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I08 compound treatment 0.373 0.119 6.39 6.3915 1.0 1606194 TimTec1_006872 CCOc1ccc(cc1)N(Cc2cccc3ccccc23)C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I09 compound treatment 0.321 0.0669 3.6 3.5971 1.0 1715376 TimTec1_006873 Cn1c(CC(O)c2cccc3ccccc23)nc4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I10 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1788181 TimTec1_006874 CC(CN1CCCCC1)OC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I11 compound treatment 0.345 0.0909 4.89 4.8868 1.0 3212032 TimTec1_006875 CCc1ccc2[nH]c(=O)c(cc2c1)C(N3CCc4ccccc4C3)c5nnnn5C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I12 compound treatment 0.251 -0.00306 -0.16 -0.1646 -1.0 1156988 TimTec1_006876 CCc1nc2ccccc2c(C(=O)Nc3cccc(Cl)c3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I13 compound treatment 0.41 0.156 8.38 8.3798 1.0 1413757 TimTec1_006877 CCOc1ccccc1NC(=O)CSc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I14 compound treatment 0.261 0.00694 0.37 0.3728 1.0 1330225 TimTec1_006878 CCCN(CCC)c1ncnc2ccc(Br)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I15 compound treatment 0.264 0.00994 0.53 0.534 1.0 1340925 TimTec1_006879 C(N1CCNCC1)c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I16 compound treatment 0.511 0.257 13.81 13.8073 1.0 1241212 TimTec1_006880 CCN1CCc2c(C#N)c(N)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I17 compound treatment 0.317 0.0629 3.38 3.3821 1.0 1412589 TimTec1_006881 Nc1c(sc2nccc(Nc3ccccc3)c12)C(=O)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I18 compound treatment 0.272 0.0179 0.96 0.9639 1.0 3212033 TimTec1_006882 CCc1noc2CC(C/C(=N/O)/c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I19 compound treatment 0.263 0.00894 0.48 0.4803 1.0 1592654 TimTec1_006883 O=C(CCN1CCCCC1)NCC2OCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I20 compound treatment 0.301 0.0469 2.52 2.5223 1.0 1513792 TimTec1_006884 O=c1oc2ccccc2n1Cn3c(=O)oc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I21 compound treatment 0.263 0.00894 0.48 0.4803 1.0 1204391 TimTec1_006885 COc1ccc(cc1)c2c(C)oc3ccc(Cl)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I22 compound treatment 0.296 0.0419 2.25 2.2536 1.0 1380204 TimTec1_006886 CCN(Cc1ccccc1)c2ccc(cc2)C3C4=C(CCCC4=O)Nc5[nH]c(=O)[nH]c(=O)c35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I23 mock treatment 0.257 0.00294 0.16 0.1579 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 I24 mock treatment 0.259 0.00494 0.27 0.2653 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J01 compound treatment 0.26 0.00594 0.32 0.3191 1.0 3087584 TimTec1_006887 Clc1nc(Cl)nc(Nc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J02 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 1255613 TimTec1_006888 CC1OC(C)C(C)C(O1)c2ccccc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J03 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 3212106 TimTec1_006889 CS(=O)(O)C1=C(O)C(=O)N(CCCC(=O)O)C1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J04 compound treatment 0.292 0.0379 2.04 2.0387 1.0 1787696 TimTec1_006890 CCCOc1cccc(NC(=O)c2occc2C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J05 compound treatment 0.307 0.0529 2.84 2.8448 1.0 1641308 TimTec1_006891 O=C(Cn1nnc(n1)c2ccccc2)N(c3ccccc3)c4ccc5ccccc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J06 compound treatment 0.283 0.0289 1.56 1.555 1.0 1234881 TimTec1_006892 Nc1ncc(Cc2cccc(Cl)c2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J07 compound treatment 0.404 0.15 8.06 8.0573 1.0 1553139 TimTec1_006893 O=S(=O)(N1CCOCC1)c2ccc3oc4ccccc4c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J08 compound treatment 0.277 0.0229 1.23 1.2326 1.0 1369411 TimTec1_006894 OC(COc1ccccc1Br)CN2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J09 compound treatment 0.256 0.00194 0.1 0.1041 1.0 3212107 TimTec1_006895 Cc1ccc(SCC(=O)NC(C)(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J10 compound treatment 0.263 0.00894 0.48 0.4803 1.0 3087605 TimTec1_006896 NC(Cc1cccc2nsnc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J11 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1081906 TimTec1_006897 Clc1ccc(OCc2ccccc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J12 compound treatment 0.493 0.239 12.84 12.84 1.0 1194697 TimTec1_006898 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)c4ccc(Cl)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J13 compound treatment 0.392 0.138 7.41 7.4125 1.0 1782465 TimTec1_006899 CNc1c(NC(=O)C)c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J14 compound treatment 0.265 0.0109 0.59 0.5878 1.0 1212146 TimTec1_006900 O=C(COc1ccccc1)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J15 compound treatment 0.444 0.19 10.21 10.2068 1.0 1194336 TimTec1_006901 COc1ccc(Nc2nc3nonc3nc2N4CCCCCC4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J16 compound treatment 0.264 0.00994 0.53 0.534 1.0 1574232 TimTec1_006902 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccs4)C(=O)C5CC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J17 compound treatment 0.32 0.0659 3.54 3.5433 1.0 1580883 TimTec1_006903 Nc1c(C#N)sc2nc(N3CCCCC3)c4CCCCc4c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J18 compound treatment 0.257 0.00294 0.16 0.1579 1.0 3212108 TimTec1_006904 CC(NC(=O)c1ccccc1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J19 compound treatment 0.275 0.0209 1.13 1.1251 1.0 1166248 TimTec1_006905 CSc1ccc(CN2CCN(Cc3cccc(C)c3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J20 compound treatment 0.243 -0.0111 -0.59 -0.5945 -1.0 3087610 TimTec1_006906 CCC(Cc1ccccc1)NC(=O)CC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J21 compound treatment 0.553 0.299 16.06 16.0643 1.0 1446397 TimTec1_006907 OC(=O)c1ccc2[nH]c3CCSCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J22 compound treatment 0.55 0.296 15.9 15.9031 1.0 1265101 TimTec1_006908 CC(CN1CCOCC1)OC(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J23 mock treatment 0.261 0.00694 0.37 0.3728 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 J24 mock treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K01 compound treatment 0.531 0.277 14.88 14.882 1.0 1298728 TimTec1_006909 Clc1ccc(OCC(=O)N(C2CCCCC2)c3ccccn3)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K02 compound treatment 0.5 0.246 13.22 13.2162 1.0 1532077 TimTec1_006910 Cc1c(C)c2cc(ccc2n1Cc3ccccc3)C(=O)OCCN4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K03 compound treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1516458 TimTec1_006911 OC1(CCN(Cc2ccccc2)[C@@H]3CCCC[C@@H]31)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K04 compound treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1296444 TimTec1_006912 Fc1ccccc1C(=O)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K05 compound treatment 0.311 0.0569 3.06 3.0597 1.0 1669803 TimTec1_006913 CC(=O)Nc1ccc(cc1)C(C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K06 compound treatment 0.261 0.00694 0.37 0.3728 1.0 3212109 TimTec1_006914 CCC1CCCCN1C(=O)c2ccc(cc2)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K07 compound treatment 0.258 0.00394 0.21 0.2116 1.0 1352014 TimTec1_006915 CCOc1ccc(CN2CCN(Cc3ccco3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K08 compound treatment 0.406 0.152 8.16 8.1648 1.0 1338673 TimTec1_006916 COc1ccc(CCNC(=O)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K09 compound treatment 0.355 0.101 5.42 5.4242 1.0 1695069 TimTec1_006917 COc1ccc(cc1)c2csc(NCC=C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K10 compound treatment 0.28 0.0259 1.39 1.3938 1.0 1788186 TimTec1_006918 CC(CN1CCOCC1)OC(=O)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K11 compound treatment 0.28 0.0259 1.39 1.3938 1.0 3212110 TimTec1_006919 CCc1ccc2[nH]c(=O)c(cc2c1)C(N3CCN(CC3)C(=O)c4ccco4)c5nnnn5C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K12 compound treatment 0.334 0.0799 4.3 4.2957 1.0 1144082 TimTec1_006920 CCc1c(C)nc2ccc(OC)cc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K13 compound treatment 0.284 0.0299 1.61 1.6088 1.0 1778845 TimTec1_006921 OC(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K14 compound treatment 0.256 0.00194 0.1 0.1041 1.0 3087618 TimTec1_006922 CCN(CC)c1scc([s+]1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K15 compound treatment 0.26 0.00594 0.32 0.3191 1.0 1353321 TimTec1_006923 CCCOc1ccc(cc1)C(=O)N2CCCC2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K16 compound treatment 0.281 0.0269 1.45 1.4476 1.0 1042930 TimTec1_006924 CC(C)CCOc1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K17 compound treatment 0.274 0.0199 1.07 1.0714 1.0 1312438 TimTec1_006925 CC(NC(=O)c1ccccc1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K18 compound treatment 0.282 0.0279 1.5 1.5013 1.0 1382221 TimTec1_006926 CCOC(=O)c1[nH]c2ccccc2c1NC=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K19 compound treatment 0.27 0.0159 0.86 0.8564 1.0 1215729 TimTec1_006927 Cc1cc2c(o1)-c3c(CCC2(C)c4ccccc4)oc5ccccc35 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K20 compound treatment 0.284 0.0299 1.61 1.6088 1.0 1052507 TimTec1_006928 OC(CC(=O)Nc1ccccc1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K21 compound treatment 0.278 0.0239 1.29 1.2864 1.0 3087624 TimTec1_006929 COC(=O)CCCCC1=C(NC(=O)C)C(CS1)NC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K22 compound treatment 0.277 0.0229 1.23 1.2326 1.0 3212111 TimTec1_006930 CC1CCN(CC1)C(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K23 mock treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 K24 mock treatment 0.253 -0.00106 -0.06 -0.0571 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L01 compound treatment 0.24 -0.0141 -0.76 -0.7557 -1.0 1026720 TimTec1_006931 Cc1nc2ccc(cc2nc1C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L02 compound treatment 0.287 0.0329 1.77 1.77 1.0 1370462 TimTec1_006932 CCc1ccc(CN2CCN(CC2)C(=O)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L03 compound treatment 0.292 0.0379 2.04 2.0387 1.0 3212112 TimTec1_006933 C(Cc1ccc2OCOc2c1)NCc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L04 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1152478 TimTec1_006934 COc1cc(cc(OC)c1OC)C(=O)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L05 compound treatment 0.253 -0.00106 -0.06 -0.0571 -1.0 1921415 TimTec1_006935 O=C(C(c1ccccc1)c2ccccc2)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L06 compound treatment 0.259 0.00494 0.27 0.2653 1.0 1655667 TimTec1_006936 OC(=O)CCNC(=O)c1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L07 compound treatment 0.281 0.0269 1.45 1.4476 1.0 1189724 TimTec1_006937 COc1ccc(cc1)C(=O)NC(C)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L08 compound treatment 0.281 0.0269 1.45 1.4476 1.0 3212113 TimTec1_006938 COc1ccc(cc1)C2CC(=O)C=C(C2)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L09 compound treatment 0.392 0.138 7.41 7.4125 1.0 3087630 TimTec1_006939 Brc1ccc(cc1)C(=O)COC(=O)Cc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L10 compound treatment 0.466 0.212 11.39 11.3891 1.0 3212114 TimTec1_006940 CC1CCN(C2CCCCC12)C(=O)c3cc4nc(cc(n4n3)C(F)(F)F)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L11 compound treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 3087632 TimTec1_006941 Nc1ccc(cc1)S(=O)(=O)CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L12 compound treatment 0.299 0.0449 2.41 2.4148 1.0 1238387 TimTec1_006942 COc1ccc2oc(C)c(C(O)c3cc4ccccc4o3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L13 compound treatment 0.279 0.0249 1.34 1.3401 1.0 1613108 TimTec1_006943 OC1=C(C(N(CC=C)C1=O)c2ccccc2Cl)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L14 compound treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1237166 TimTec1_006944 Cc1ccc(cc1)C(N)(CC=C)CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L15 compound treatment 0.251 -0.00306 -0.16 -0.1646 -1.0 1169243 TimTec1_006945 CC1(C)CC(CCO1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L16 compound treatment 0.447 0.193 10.37 10.3681 1.0 3212188 TimTec1_006946 Cc1ccsc1/C=N/c2ccc(Nc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L17 compound treatment 0.271 0.0169 0.91 0.9102 1.0 1316960 TimTec1_006947 CC1(C)Cc2c(CO1)c(nc3sc(C#N)c(N)c23)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L18 compound treatment 0.275 0.0209 1.13 1.1251 1.0 1615665 TimTec1_006948 CCCCn1c(=O)c(C(=O)Nc2nccs2)c(O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L19 compound treatment 0.469 0.215 11.55 11.5503 1.0 1477509 TimTec1_006949 O=C(Oc1ccccc1)Oc2ccc3c(c2)oc(=O)c4ccccc43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L20 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1785312 TimTec1_006950 CCc1c(C(=O)O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L21 compound treatment 0.454 0.2 10.74 10.7442 1.0 1349942 TimTec1_006951 Cc1cccc(NC(=O)c2ccc(Br)o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L22 compound treatment 0.277 0.0229 1.23 1.2326 1.0 1693483 TimTec1_006952 OC(=O)c1ccc(cc1)C2Nc3ccccc3C4C=CCC42 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L23 mock treatment 0.252 -0.00206 -0.11 -0.1108 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 L24 mock treatment 0.257 0.00294 0.16 0.1579 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M01 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 3087638 TimTec1_006953 C[N+]1(CCC(=N1)N)c2cccc(c2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M02 compound treatment 0.277 0.0229 1.23 1.2326 1.0 1194545 TimTec1_006954 OC(=O)COc1cccc2nsnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M03 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1448407 TimTec1_006955 CCOC(=O)C1=C(NC(=O)c2ccccc2)c3ccccc3CC41CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M04 compound treatment 0.287 0.0329 1.77 1.77 1.0 1380989 TimTec1_006956 COC(=O)C1=C(C)NC2=C(C1c3cccc4ccccc34)C(=O)CC(C2)c5ccc(OC)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M05 compound treatment 0.38 0.126 6.77 6.7676 1.0 1304492 TimTec1_006957 Fc1ccc(cc1)C(=O)CCCN2Cc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M06 compound treatment 0.436 0.182 9.78 9.7769 1.0 1290371 TimTec1_006958 CCCn1c2nc(C)c(C(=O)c3cccs3)n2c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M07 compound treatment 0.263 0.00894 0.48 0.4803 1.0 1210412 TimTec1_006959 Cc1ccc(NC(=O)c2c3CCCCc3nc4ccccc24)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M08 compound treatment 0.466 0.212 11.39 11.3891 1.0 1472306 TimTec1_006960 Cc1ccc2nc(NC(=O)c3ccccc3F)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M09 compound treatment 0.278 0.0239 1.29 1.2864 1.0 3212189 TimTec1_006961 CCN(CC)c1ccc(C=C2C(=O)N(C)C(=O)N(C)C2=O)c(OCc3ccc(Cl)cc3Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M10 compound treatment 0.363 0.109 5.85 5.8541 1.0 1788812 TimTec1_006962 CC1=Nc2ccccc2NC(=O)C1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M11 compound treatment 0.253 -0.00106 -0.06 -0.0571 -1.0 1185528 TimTec1_006963 CCCOc1ccc(cc1OC)C(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M12 compound treatment 0.249 -0.00506 -0.27 -0.272 -1.0 1123483 TimTec1_006964 CC(C)N1CCN(CC1)C(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M13 compound treatment 0.286 0.0319 1.72 1.7163 1.0 3087674 TimTec1_006965 COc1ccc(CNc2ccccc2)cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M14 compound treatment 0.272 0.0179 0.96 0.9639 1.0 3212190 TimTec1_006966 N1c2ccccc2[S+](c3ccccc3)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M15 compound treatment 0.487 0.233 12.52 12.5176 1.0 1703037 TimTec1_006967 CCOC(=O)c1ccc(NC(=O)C2C3CCCCC23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M16 compound treatment 0.291 0.0369 1.98 1.9849 1.0 1401277 TimTec1_006968 O=C(N1CCn2c1nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M17 compound treatment 0.428 0.174 9.35 9.347 1.0 3087677 TimTec1_006969 CCn1c(nc2ccccc12)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M18 compound treatment 0.254 -6.25E-5 0.0 -0.0034 -1.0 3087679 TimTec1_006970 CC1=CC(C)(C)NC(=O)N1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M19 compound treatment 0.286 0.0319 1.72 1.7163 1.0 1777670 TimTec1_006971 COc1ccc(/C=C/C2=CCN(Cc3ccccc3)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M20 compound treatment 0.272 0.0179 0.96 0.9639 1.0 3212191 TimTec1_006972 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)NCc5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M21 compound treatment 0.301 0.0469 2.52 2.5223 1.0 1654108 TimTec1_006973 Sc1nnc([nH]1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M22 compound treatment 0.409 0.155 8.33 8.326 1.0 3212192 TimTec1_006974 O/N=C\1/CCCc2nn(nc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M23 mock treatment 0.257 0.00294 0.16 0.1579 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 M24 mock treatment 0.255 9.37E-4 0.05 0.0504 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N01 compound treatment 0.291 0.0369 1.98 1.9849 1.0 1462528 TimTec1_006975 CCOC(=O)c1c(NC(=O)c2cc3ccccc3o2)sc4COC(C)(C)Cc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N02 compound treatment 0.276 0.0219 1.18 1.1789 1.0 1444731 TimTec1_006976 COc1ccc2nc(nc(N3CCCCC3)c2c1)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N03 compound treatment 0.289 0.0349 1.88 1.8775 1.0 3212193 TimTec1_006977 NC(=O)CSc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N04 compound treatment 0.394 0.14 7.52 7.5199 1.0 3087684 TimTec1_006978 COC(=O)c1ccc(Nc2nc(c(C)s2)c3ccc(Br)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N05 compound treatment 0.281 0.0269 1.45 1.4476 1.0 3212194 TimTec1_006979 CC(C)(C)c1ccc(cc1)c2nnnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N06 compound treatment 0.253 -0.00106 -0.06 -0.0571 -1.0 1782862 TimTec1_006980 O=C(CCNc1n[nH]c(=O)[nH]c1=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N07 compound treatment 0.238 -0.0161 -0.86 -0.8632 -1.0 1650008 TimTec1_006981 Cc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N08 compound treatment 0.248 -0.00606 -0.33 -0.3258 -1.0 1497501 TimTec1_006982 CC1CCN(CCC(=O)Nc2ccccc2F)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N09 compound treatment 0.372 0.118 6.34 6.3377 1.0 1669677 TimTec1_006983 CCOC(=O)c1c(NC(=S)NCC(=C)C)scc1c2ccsc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N10 compound treatment 0.248 -0.00606 -0.33 -0.3258 -1.0 3212195 TimTec1_006984 Oc1ccccc1C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N11 compound treatment 0.238 -0.0161 -0.86 -0.8632 -1.0 1273018 TimTec1_006985 CC1=CC(C)(C)c2ccccc2N1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N12 compound treatment 0.309 0.0549 2.95 2.9522 1.0 3212196 TimTec1_006986 CCc1c(C)nc2ccc(C)cc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N13 compound treatment 0.243 -0.0111 -0.59 -0.5945 -1.0 1280587 TimTec1_006987 C(NC1CCCCC1)C2OCc3ccccc3CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N14 compound treatment 0.27 0.0159 0.86 0.8564 1.0 1270926 TimTec1_006988 OC(=O)CCC(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N15 compound treatment 0.275 0.0209 1.13 1.1251 1.0 1479468 TimTec1_006989 O=C(NC(c1ccccc1)c2ccccc2)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N16 compound treatment 0.432 0.178 9.56 9.562 1.0 1290955 TimTec1_006990 OCCN(CCO)C(=O)COc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N17 compound treatment 0.487 0.233 12.52 12.5176 1.0 3212197 TimTec1_006991 CC(C)(C)c1ccc(OCc2nnc(SCC(=O)N)n2c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N18 compound treatment 0.238 -0.0161 -0.86 -0.8632 -1.0 1452106 TimTec1_006992 CCC(=O)NC(c1ccc(cc1)C(C)C)c2c(O)ccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N19 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1151230 TimTec1_006993 CC1(CN(Cc2ccccc2)CC3(C)CN(Cc4ccccc4)C1)C3=NO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N20 compound treatment 0.248 -0.00606 -0.33 -0.3258 -1.0 3087690 TimTec1_006994 NC(=O)c/1cc2ccccc2o\c1=N/O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N21 compound treatment 0.256 0.00194 0.1 0.1041 1.0 1301823 TimTec1_006995 OC(=O)CCS(=O)(=O)c1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N22 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1570261 TimTec1_006996 CN(C)S(=O)(=O)Nc1ccc(cc1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N23 mock treatment 0.251 -0.00306 -0.16 -0.1646 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 N24 mock treatment 0.247 -0.00706 -0.38 -0.3795 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O01 compound treatment 0.421 0.167 8.97 8.9709 1.0 1350651 TimTec1_006997 COc1cccc(CC(Cc2nc3ccccc3[nH]2)c4nc5ccccc5[nH]4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O02 compound treatment 0.295 0.0409 2.2 2.1999 1.0 1318205 TimTec1_006998 Cc1ccc(Cc2cnc(NC(=O)C(c3ccccc3)c4ccccc4)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O03 compound treatment 0.378 0.124 6.66 6.6601 1.0 1553933 TimTec1_006999 Cc1cc(SCC(=O)N2CCCCC2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O04 compound treatment 0.241 -0.0131 -0.7 -0.702 -1.0 1159118 TimTec1_007000 Cc1cc(C(=O)O)c2cc(F)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O05 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 1599562 TimTec1_007001 C(CN1CCNCC1)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O06 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 3087694 TimTec1_007002 CC1CC(n2nc(cc2N1)C(=O)O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O07 compound treatment 0.263 0.00894 0.48 0.4803 1.0 1578115 TimTec1_007003 C(N1CCN(Cc2ccncc2)CC1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O08 compound treatment 0.272 0.0179 0.96 0.9639 1.0 1918993 TimTec1_007004 Oc1ccc(O)c(c1)[S+]2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O09 compound treatment 0.29 0.0359 1.93 1.9312 1.0 3212273 TimTec1_007005 O=C1NC(=C(C#N)C2(CCCC2)C1C#N)SCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O10 compound treatment 0.472 0.218 11.71 11.7115 1.0 1427630 TimTec1_007006 Clc1ccc(OCc2cn3ccccc3n2)c4ncccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O11 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1738341 TimTec1_007007 O=C(NCc1ccccc1)C2C3CCCCC23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O12 compound treatment 0.255 9.37E-4 0.05 0.0504 1.0 1437987 TimTec1_007008 COc1ccc(cc1)C(=O)NC(CC(C)C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O13 compound treatment 0.468 0.214 11.5 11.4966 1.0 3212274 TimTec1_007009 COc1ccc(Nc2nc(cs2)c3cccs3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O14 compound treatment 0.256 0.00194 0.1 0.1041 1.0 1279048 TimTec1_007010 Cc1ccc(NC(=O)CCN2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O15 compound treatment 0.274 0.0199 1.07 1.0714 1.0 1265764 TimTec1_007011 COc1cc(OC)c(OC)cc1CN2CCN(CC2)C(=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O16 compound treatment 0.328 0.0739 3.97 3.9732 1.0 3087714 TimTec1_007012 CNc1nc(cc(n1)c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O17 compound treatment 0.407 0.153 8.22 8.2185 1.0 1652569 TimTec1_007013 C=C1C(C1C(=O)Nc2ccc3OCCOc3c2)C(=O)Nc4ccc5OCCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O18 compound treatment 0.272 0.0179 0.96 0.9639 1.0 3086771 TimTec1_007014 CCN(CC)CCn1cnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O19 compound treatment 0.417 0.163 8.76 8.7559 1.0 1705111 TimTec1_007015 COc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O20 compound treatment 0.302 0.0479 2.58 2.5761 1.0 3212275 TimTec1_007016 OC(=O)c1ccccc1NS(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O21 compound treatment 0.282 0.0279 1.5 1.5013 1.0 1788989 TimTec1_007017 CCOC(=O)c1c(C)nc2ccccc2c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O22 compound treatment 0.479 0.225 12.09 12.0877 1.0 1226950 TimTec1_007018 CC(C)c1ccc2oc(nc2c1)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O23 mock treatment 0.258 0.00394 0.21 0.2116 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 O24 mock treatment 0.256 0.00194 0.1 0.1041 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P01 compound treatment 0.263 0.00894 0.48 0.4803 1.0 3086772 TimTec1_007019 Cc1ccc(NCCNc2ccc(C)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P02 compound treatment 0.266 0.0119 0.64 0.6415 1.0 1505666 TimTec1_007020 Cc1sc(NC(=O)c2ccccc2F)c(C(=O)c3ccc(Cl)cc3)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P03 compound treatment 0.464 0.21 11.28 11.2816 1.0 3212276 TimTec1_007021 CC(C)c1ccc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccco4)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P04 compound treatment 0.558 0.304 16.33 16.333 1.0 1372504 TimTec1_007022 Nc1ccccc1SCC(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P05 compound treatment 0.262 0.00794 0.43 0.4265 1.0 1334056 TimTec1_007023 CC(=O)Nc1cc2OCCOc2cc1N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P06 compound treatment 0.244 -0.0101 -0.54 -0.5407 -1.0 1286842 TimTec1_007024 CC(C(=O)Nc1cccc(C)c1)C(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P07 compound treatment 0.246 -0.00806 -0.43 -0.4333 -1.0 1511538 TimTec1_007025 Cc1cc(nc(n1)c2ccc(Br)cc2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P08 compound treatment 0.236 -0.0181 -0.97 -0.9706 -1.0 3212277 TimTec1_007026 CCCC/C(=N\O)/c1c(C)[nH]c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P09 compound treatment 0.385 0.131 7.04 7.0363 1.0 1544658 TimTec1_007027 O=c1oc2ccccc2cc1c3csc(n3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P10 compound treatment 0.35 0.0959 5.16 5.1555 1.0 1397424 TimTec1_007028 Cc1ccc2cc(C)c(NCc3cccnc3)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P11 compound treatment 0.27 0.0159 0.86 0.8564 1.0 3212278 TimTec1_007029 Cc1nc(nc(O)c1CC=C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P12 compound treatment 0.236 -0.0181 -0.97 -0.9706 -1.0 3086773 TimTec1_007030 CC1(C)CC(=O)C=C(C1)NN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P13 compound treatment 0.237 -0.0171 -0.92 -0.9169 -1.0 1421894 TimTec1_007031 Cc1ccc(O)c(c1)c2cc([nH]n2)c3ccc(cc3)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P14 compound treatment 0.517 0.263 14.13 14.1297 1.0 1581406 TimTec1_007032 Cc1ccccc1OCC(=O)Nc2cccc(c2)N3C(=O)c4ccccc4C3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P15 compound treatment 0.276 0.0219 1.18 1.1789 1.0 3086774 TimTec1_007033 O=S(=O)(Nc1ccc2ccccc2c1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P16 compound treatment 0.248 -0.00606 -0.33 -0.3258 -1.0 3212279 TimTec1_007034 OC(=O)CCCNC1=NC(=O)CC(=O)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P17 compound treatment 0.402 0.148 7.95 7.9499 1.0 1305963 TimTec1_007035 Cc1ccc(cc1S(=O)(=O)N)c2nnc(Nc3ccc(cc3)S(=O)(=O)N)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P18 compound treatment 0.245 -0.00906 -0.49 -0.487 -1.0 3086775 TimTec1_007036 CCN(CC)C(=O)C1CC(=O)OC1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P19 compound treatment 0.237 -0.0171 -0.92 -0.9169 -1.0 1786463 TimTec1_007037 CC1(C)CC2(CCCN(CCCN3CCCC4(CCOC(C)(C)C4)C3)C2)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P20 compound treatment 0.259 0.00494 0.27 0.2653 1.0 1468821 TimTec1_007038 O=C(OCC1CCCN2CCCCC12)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P21 compound treatment 0.242 -0.0121 -0.65 -0.6482 -1.0 1531258 TimTec1_007039 CCNC(=S)Nc1c(C)n(C)n(c2ccccc2)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P22 compound treatment 0.278 0.0239 1.29 1.2864 1.0 1580338 TimTec1_007040 CC(=O)N(CC(=O)Nc1ccc(C)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P23 mock treatment 0.241 -0.0131 -0.7 -0.702 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2082 P24 mock treatment 0.241 -0.0131 -0.7 -0.702 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A01 compound treatment 0.298 0.0456 2.45 2.4518 1.0 1553711 TimTec1_007041 CC(=O)N1CCN(CC1)c2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A02 compound treatment 0.234 -0.0184 -0.99 -0.9874 -1.0 3212280 TimTec1_007042 Cc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A03 compound treatment 0.306 0.0536 2.88 2.8817 1.0 3212281 TimTec1_007043 O=C(CSc1ncnc2sc3CCCCc3c12)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A04 compound treatment 0.287 0.0346 1.86 1.8607 1.0 1162667 TimTec1_007044 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2cccc(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A05 compound treatment 0.43 0.178 9.55 9.5452 1.0 3212282 TimTec1_007045 Nc1ccc(cc1Cl)c2nc3ccc(N)c(Cl)c3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A06 compound treatment 0.508 0.256 13.74 13.7368 1.0 1490444 TimTec1_007046 CC(=O)Nc1ccc(cc1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A07 compound treatment 0.246 -0.00638 -0.34 -0.3426 -1.0 1550978 TimTec1_007047 CCOC(=O)c1c(NC(=O)COC(=O)c2cn(CC)c3nc(C)ccc3c2=O)sc4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A08 compound treatment 0.375 0.123 6.59 6.5896 1.0 1241536 TimTec1_007048 Cc1c(C)c2ccc(OCC(=O)N)cc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A09 compound treatment 0.319 0.0666 3.58 3.5803 1.0 1694138 TimTec1_007049 Nc1ccc(NC(=O)CCN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A10 compound treatment 0.374 0.122 6.54 6.5359 1.0 1593211 TimTec1_007050 Nn1c(Nc2ccccc2)nc3sc4CCCc4c3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A11 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1077423 TimTec1_007051 CC(c1ccccc1)n2cncc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A12 compound treatment 0.263 0.0106 0.57 0.571 1.0 3212283 TimTec1_007052 Cn1c(nc2ccccc12)c3nonc3NC(=O)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A13 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 3086776 TimTec1_007053 CN(C(=O)C)c1nc(N)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A14 compound treatment 0.258 0.00562 0.3 0.3023 1.0 1377163 TimTec1_007054 COc1ccc(CCNC2(Cc3ccccc3)CC(C)N(C)CC2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A15 compound treatment 0.245 -0.00738 -0.4 -0.3963 -1.0 3086777 TimTec1_007055 CCCSc1ncnc2sc3CCCCc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A16 compound treatment 0.502 0.25 13.41 13.4143 1.0 1617565 TimTec1_007056 O=C(Oc1ccccn1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A17 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1378399 TimTec1_007057 CC(C)Oc1ccccc1C(=O)NC(CO)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A18 compound treatment 0.457 0.205 11.0 10.9961 1.0 1498887 TimTec1_007058 Cc1ccc(cc1)C(=O)CNc2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A19 compound treatment 0.303 0.0506 2.72 2.7205 1.0 3086778 TimTec1_007059 CCC(C)(C)C(=O)Nc1nnc(s1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A20 compound treatment 0.26 0.00762 0.41 0.4098 1.0 1197829 TimTec1_007060 OC(=O)CCC(=O)Nc1cc(Cl)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A21 compound treatment 0.264 0.0116 0.62 0.6247 1.0 1218361 TimTec1_007061 CC(C)(C)c1cn2c(nc3ccccc32)n1CCN4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A22 compound treatment 0.272 0.0196 1.05 1.0546 1.0 3086779 TimTec1_007062 CCOc1ccc(cc1)C2C(=CN(CCOC)C=C2C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A23 mock treatment 0.263 0.0106 0.57 0.571 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 A24 mock treatment 0.266 0.0136 0.73 0.7322 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B01 compound treatment 0.349 0.0966 5.19 5.1924 1.0 3212284 TimTec1_007063 O=C(NCCNC1=NS(=O)(=O)c2ccccc12)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B02 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1124094 TimTec1_007064 CC1CCN(CC1)C(=O)C2C(C3CC2C=C3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B03 compound treatment 0.492 0.24 12.88 12.8769 1.0 1411725 TimTec1_007065 Nc1ccc(cc1)c2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B04 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 1787257 TimTec1_007066 Cn1c(=O)[nH]c(=O)c2n(CCN3CCOCC3)cnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B05 compound treatment 0.239 -0.0134 -0.72 -0.7187 -1.0 1500476 TimTec1_007067 COC1CCCCC1Nc2cc(C)ccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B06 compound treatment 0.351 0.0986 5.3 5.2999 1.0 3212358 TimTec1_007068 COC(=O)COc1ccc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B07 compound treatment 0.288 0.0356 1.91 1.9144 1.0 3086780 TimTec1_007069 Cc1ccc(NCC2COc3ccccc3O2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B08 compound treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 3212359 TimTec1_007070 FC(F)(F)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B09 compound treatment 0.255 0.00262 0.14 0.1411 1.0 3086781 TimTec1_007071 S=c1n(CCC#N)c2ccccc2n1CCC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B10 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1615066 TimTec1_007072 Cc1cc(nc(n1)N2CCOCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B11 compound treatment 0.256 0.00362 0.19 0.1948 1.0 1329642 TimTec1_007073 OC(C(O)C(=O)Nc1ccccc1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B12 compound treatment 0.245 -0.00738 -0.4 -0.3963 -1.0 3086783 TimTec1_007074 COc1ccc(cc1)N(C(C(=O)NC2CCCCC2)c3ccc(C)o3)C(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B13 compound treatment 0.294 0.0416 2.24 2.2368 1.0 1156856 TimTec1_007075 COc1ccc(Cl)cc1NC(=O)CN(C2CCCCC2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B14 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 3086785 TimTec1_007076 Cc1cc(N)n(n1)C2CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B15 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 3212360 TimTec1_007077 CN1CCCC(C1)OC(=O)C(C)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B16 compound treatment 0.374 0.122 6.54 6.5359 1.0 1215637 TimTec1_007078 Nc1ccc(CCc2nc3ccccc3o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B17 compound treatment 0.473 0.221 11.86 11.8559 1.0 1249972 TimTec1_007079 CN(C)Cc1c(O)ccc2c(C)cc(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B18 compound treatment 0.254 0.00162 0.09 0.0873 1.0 1386364 TimTec1_007080 CCn1ccnc1C(O)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B19 compound treatment 0.491 0.239 12.82 12.8232 1.0 3086788 TimTec1_007081 CCSc1nsc(SCC)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B20 compound treatment 0.515 0.263 14.11 14.1129 1.0 3212361 TimTec1_007082 Cc1cc(NC(=O)c2sc(Nc3cccc(c3)C(F)(F)F)nc2N)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B21 compound treatment 0.261 0.00862 0.46 0.4635 1.0 3086790 TimTec1_007083 CN/1CCC\C1=N/c2ccccc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B22 compound treatment 0.286 0.0336 1.81 1.8069 1.0 1642345 TimTec1_007084 CCCn1c(=O)c(C(=O)NCc2ccccc2)c(O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B23 mock treatment 0.258 0.00562 0.3 0.3023 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 B24 mock treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C01 compound treatment 0.227 -0.0254 -1.36 -1.3636 -1.0 3086791 TimTec1_007085 O=C(C(Cc1ccccc1)N2C(=O)C3C4CC(C=C4)C3C2=O)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C02 compound treatment 0.272 0.0196 1.05 1.0546 1.0 3212362 TimTec1_007086 COc1ccc(cc1)N2C(=O)CC2(/C=C/c3ccccc3)C(=O)NC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C03 compound treatment 0.255 0.00262 0.14 0.1411 1.0 3086839 TimTec1_007087 O=C(CSc1ncnc2sc3CCCCc3c12)OC4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C04 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1133272 TimTec1_007088 O=C(NCC1CCCO1)C2CCN(CC3CCCCC3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C05 compound treatment 0.274 0.0216 1.16 1.1621 1.0 1372624 TimTec1_007089 CCN(CC)c1nc(nc2ccccc12)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C06 compound treatment 0.269 0.0166 0.89 0.8934 1.0 1360767 TimTec1_007090 CCC(=O)Nc1sc2CCCCc2c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C07 compound treatment 0.488 0.236 12.66 12.662 1.0 3212363 TimTec1_007091 CCOC(=O)c1sc(NC(=O)C(CC)OC(=O)c2c3CCCc3nc4ccccc24)nc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C08 compound treatment 0.486 0.234 12.55 12.5545 1.0 3086844 TimTec1_007092 Clc1ccc2oc(=O)c(cc2c1)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C09 compound treatment 0.242 -0.0104 -0.56 -0.5575 -1.0 3212364 TimTec1_007093 OC(=O)C1Cc2[nH]cnc2C(N1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C10 compound treatment 0.236 -0.0164 -0.88 -0.88 -1.0 3086846 TimTec1_007094 Cc1cc(C)n(CCSCC(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C11 compound treatment 0.417 0.165 8.85 8.8466 1.0 1326461 TimTec1_007095 O=C(COc1ccc2ccccc2c1)NCc3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C12 compound treatment 0.281 0.0286 1.54 1.5382 1.0 3086847 TimTec1_007096 Cc1csc(NC(=O)c2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C13 compound treatment 0.317 0.0646 3.47 3.4728 1.0 1250239 TimTec1_007097 Brc1cc(Br)c2oc(=O)c(cc2c1)C(=O)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C14 compound treatment 0.311 0.0586 3.15 3.1504 1.0 3212365 TimTec1_007098 COc1cc(SC)ccc1C(=O)Nc2nnc(s2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C15 compound treatment 0.281 0.0286 1.54 1.5382 1.0 1524512 TimTec1_007099 Nc1ccc2[nH]c(nc2c1)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C16 compound treatment 0.245 -0.00738 -0.4 -0.3963 -1.0 1424180 TimTec1_007100 OC(=O)c1ccc(NC(=O)C2CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C17 compound treatment 0.51 0.258 13.84 13.8442 1.0 1263746 TimTec1_007101 Oc1c2CCCc2nc3cc(nn13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C18 compound treatment 0.325 0.0726 3.9 3.9027 1.0 1917903 TimTec1_007102 OC(=O)c1sc2cc(F)ccc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C19 compound treatment 0.567 0.315 16.91 16.9073 1.0 1724549 TimTec1_007103 Clc1ccc(OCC(=O)Nc2cccc(Cl)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C20 compound treatment 0.261 0.00862 0.46 0.4635 1.0 1611210 TimTec1_007104 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C21 compound treatment 0.268 0.0156 0.84 0.8397 1.0 1785828 TimTec1_007105 CCOC(=O)c1c(O)c2CCCCc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C22 compound treatment 0.262 0.00962 0.52 0.5172 1.0 3212366 TimTec1_007106 COc1ccc(cc1OC)C(N(C(=O)c2cc[nH]n2)c3ccc(F)cc3)C(=O)NC4CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C23 mock treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 C24 mock treatment 0.256 0.00362 0.19 0.1948 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D01 compound treatment 0.335 0.0826 4.44 4.4401 1.0 3086852 TimTec1_007107 Oc1ccc(cc1)N(Cc2cccs2)C3=NS(=O)(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D02 compound treatment 0.39 0.138 7.4 7.3957 1.0 1609213 TimTec1_007108 Clc1ccc(cc1)c2csc(n2)N3CCNC(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D03 compound treatment 0.257 0.00462 0.25 0.2485 1.0 1349191 TimTec1_007109 Cc1ccc(NC(=O)CC2(C)Nc3ccccc3C(=O)N2c4ccccc4C)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D04 compound treatment 0.256 0.00362 0.19 0.1948 1.0 1386349 TimTec1_007110 CCCCc1c(nc(N)c(C#N)c1c2ccc(O)c(OC)c2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D05 compound treatment 0.237 -0.0154 -0.83 -0.8262 -1.0 3086855 TimTec1_007111 Cc1ccccc1C(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D06 compound treatment 0.28 0.0276 1.48 1.4845 1.0 3212367 TimTec1_007112 Fc1ccc(NC(=O)CSc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D07 compound treatment 0.328 0.0756 4.06 4.0639 1.0 1055578 TimTec1_007113 Cc1nc2cc(Cl)ccc2n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D08 compound treatment 0.238 -0.0144 -0.77 -0.7725 -1.0 1411696 TimTec1_007114 Cc1nc2c(nc(C)nc2o1)n3cc(F)c(=O)[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D09 compound treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1520665 TimTec1_007115 NNC(=O)CC(=O)NC1(Cc2ccc(O)cc2)CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D10 compound treatment 0.239 -0.0134 -0.72 -0.7187 -1.0 1312726 TimTec1_007116 CCOc1ccc2[nH]c(=O)c(cc2c1)C(N3CCc4ccccc34)c5nnnn5CCOC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D11 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1686790 TimTec1_007117 CC(=O)N(c1ccccc1)c2nc(C)cc(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D12 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 3086859 TimTec1_007118 OC(=O)c1cccc2CN(C3CCCCC3)C(=O)c21 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D13 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 3212368 TimTec1_007119 Cc1ccc(cc1F)N(C(C(=O)NC2CCCC2)c3cccs3)C(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D14 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 3086861 TimTec1_007120 COc1cccc(c1)N(C(C(=O)NC2CCCC2)c3cccs3)C(=O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D15 compound treatment 0.229 -0.0234 -1.26 -1.2561 -1.0 3086982 TimTec1_007121 CN1CCN(CC1)C(=O)c2cc(cc(c2)C(C)(C)C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D16 compound treatment 0.283 0.0306 1.65 1.6457 1.0 3212443 TimTec1_007122 COc1cc(cc(OC)c1OC)C(=O)N(Cc2ccccc2)Cc3cc4ccc(C)cc4[nH]c3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D17 compound treatment 0.392 0.14 7.5 7.5032 1.0 1384457 TimTec1_007123 CN(Cc1ccccc1)C(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D18 compound treatment 0.383 0.131 7.02 7.0195 1.0 1679436 TimTec1_007124 COc1ccc2CCc3sc(N)nc3-c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D19 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 1259187 TimTec1_007125 O=C1N(CN2CCN(Cc3ccc4OCOc4c3)CC2)C(=O)c5ccccc15 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D20 compound treatment 0.242 -0.0104 -0.56 -0.5575 -1.0 3086919 TimTec1_007126 CC(C)(C)c1cc(c2c(N)c(sc2n1)C(=O)NC3CC3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D21 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 3212444 TimTec1_007127 CCN(CC)Cc1cc(C(=O)O)c(o1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D22 compound treatment 0.262 0.00962 0.52 0.5172 1.0 1398660 TimTec1_007128 Cc1cc(C(=O)O)c2cc(O)ccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D23 mock treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 D24 mock treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E01 compound treatment 0.493 0.241 12.93 12.9307 1.0 1226206 TimTec1_007129 CC(C)(C)CC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E02 compound treatment 0.33 0.0776 4.17 4.1714 1.0 1700538 TimTec1_007130 CCNc1nc2nonc2nc1NCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E03 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1567862 TimTec1_007131 Oc1c(C(=O)NC2CCCC2)c(=O)n3CCc4cccc1c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E04 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1647305 TimTec1_007132 Cc1cc(on1)C2C(CC(=O)CC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E05 compound treatment 0.259 0.00662 0.36 0.356 1.0 1721107 TimTec1_007133 COc1cc(OC)cc(c1)C(=O)Nc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E06 compound treatment 0.478 0.226 12.12 12.1246 1.0 1113188 TimTec1_007134 COc1ccc(cc1)c2onc3ccc(Cl)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E07 compound treatment 0.276 0.0236 1.27 1.2696 1.0 3212445 TimTec1_007135 COc1c2C=CC(=O)C(CC=C(C)C)(OC)c2nc3occc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E08 compound treatment 0.291 0.0386 2.08 2.0756 1.0 1237484 TimTec1_007136 Cc1cc(C)nc(NCC(O)CNc2ccccc2C)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E09 compound treatment 0.325 0.0726 3.9 3.9027 1.0 1749456 TimTec1_007137 CCOc1ccc(NC(=O)c2cnccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E10 compound treatment 0.287 0.0346 1.86 1.8607 1.0 1786928 TimTec1_007138 CCOc1ccc2nc(SCC(=O)OC3CCCCC3)c(C)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E11 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1398984 TimTec1_007139 Clc1ccc(cc1)n2c(=O)c3cc4c(=O)n(c5ccc(Cl)cc5)c(=O)c4cc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E12 compound treatment 0.261 0.00862 0.46 0.4635 1.0 1228877 TimTec1_007140 C(Nc1c2CCCc2nc3ccccc13)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E13 compound treatment 0.27 0.0176 0.95 0.9471 1.0 3212446 TimTec1_007141 COC(=O)CC1OC(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E14 compound treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1386546 TimTec1_007142 CC1CC(C)CN(CCC(=O)Nc2ccccc2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E15 compound treatment 0.292 0.0396 2.13 2.1294 1.0 1311552 TimTec1_007143 O=C(Nc1ccncc1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E16 compound treatment 0.271 0.0186 1.0 1.0009 1.0 1687129 TimTec1_007144 O=C(NCC1CCCO1)c2ccc(CN3CCc4ccccc4C3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E17 compound treatment 0.288 0.0356 1.91 1.9144 1.0 3212447 TimTec1_007145 CCCCc1n[nH]c2CC(C/C(=N/O)/c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E18 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1208623 TimTec1_007146 CCCc1nc2ccccc2n1CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E19 compound treatment 0.257 0.00462 0.25 0.2485 1.0 3212448 TimTec1_007147 CCN(CC)CC(=O)OC1CC2CCC1(C)C2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E20 compound treatment 0.27 0.0176 0.95 0.9471 1.0 1568959 TimTec1_007148 CC1CCc2c(C(=O)N3CCCCC3)c(NC(=O)c4ccccc4)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E21 compound treatment 0.266 0.0136 0.73 0.7322 1.0 1089037 TimTec1_007149 O=C(Nc1ccccc1)C2C(C3CC2C=C3)C(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E22 compound treatment 0.263 0.0106 0.57 0.571 1.0 1510856 TimTec1_007150 COc1ccc(NC(=O)CCN2CCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E23 mock treatment 0.261 0.00862 0.46 0.4635 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 E24 mock treatment 0.253 6.25E-4 0.03 0.0336 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F01 compound treatment 0.298 0.0456 2.45 2.4518 1.0 3212449 TimTec1_007151 COc1ccc(cc1)C(O)CNc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F02 compound treatment 0.25 -0.00238 -0.13 -0.1276 -1.0 1155968 TimTec1_007152 CC(C)C1Nc2ccc(cc2C3C=CCC31)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F03 compound treatment 0.255 0.00262 0.14 0.1411 1.0 1259120 TimTec1_007153 CC(=O)Nc1c([nH]c2ccccc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F04 compound treatment 0.25 -0.00238 -0.13 -0.1276 -1.0 3212450 TimTec1_007154 Cc1ccc2[nH]c(=O)c(CN(C3CCCCC3)C(=O)c4cccs4)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F05 compound treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1251350 TimTec1_007155 COc1ccc(CNCc2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F06 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 1187651 TimTec1_007156 OCc1ccccc1CNC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F07 compound treatment 0.409 0.157 8.42 8.4167 1.0 3086933 TimTec1_007157 Clc1ccc(Cn2nnc(n2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F08 compound treatment 0.233 -0.0194 -1.04 -1.0412 -1.0 1430421 TimTec1_007158 Cc1cccc(NC(=O)C2(CCOCC2)c3ccccc3)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F09 compound treatment 0.539 0.287 15.4 15.4026 1.0 1706906 TimTec1_007159 O=C(Cc1cccs1)Nc2cccc(c2)c3nnc(o3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F10 compound treatment 0.238 -0.0144 -0.77 -0.7725 -1.0 1276179 TimTec1_007160 OCC(C(=O)OC1CN2CCC1CC2)(c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F11 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1576381 TimTec1_007161 CCN1CCN(CC1)C(=O)c2ccc(NC(=O)C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F12 compound treatment 0.259 0.00662 0.36 0.356 1.0 1346949 TimTec1_007162 O=C(NC(c1ccccc1)c2ccccc2)C3COC4C=CC=CC4O3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F13 compound treatment 0.239 -0.0134 -0.72 -0.7187 -1.0 3086988 TimTec1_007163 CCCN1C(=O)C(O)(C/C(=N\O)/C)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F14 compound treatment 0.255 0.00262 0.14 0.1411 1.0 1714688 TimTec1_007164 Cc1ccc(cc1)C2(CC(=O)Nc3ccccc3C)CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F15 compound treatment 0.25 -0.00238 -0.13 -0.1276 -1.0 1704815 TimTec1_007165 O=C(Cc1cccs1)NC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F16 compound treatment 0.254 0.00162 0.09 0.0873 1.0 3212451 TimTec1_007166 O=C(NC1CCCC1)C(N(Cc2cccs2)C(=O)c3csnn3)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F17 compound treatment 0.235 -0.0174 -0.93 -0.9337 -1.0 3086991 TimTec1_007167 CCCC(NC(=O)c1ccco1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F18 compound treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1420604 TimTec1_007168 C(CN1CCNCC1)OC(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F19 compound treatment 0.284 0.0316 1.7 1.6995 1.0 1477182 TimTec1_007169 O=C(CC1c2ccccc2Oc3ccccc13)NCc4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F20 compound treatment 0.339 0.0866 4.66 4.655 1.0 3212452 TimTec1_007170 COc1ccc(cc1)C(=O)CN2C(=O)COc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F21 compound treatment 0.253 6.25E-4 0.03 0.0336 1.0 3086994 TimTec1_007171 CCc1ccc(CN2CCNCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F22 compound treatment 0.406 0.154 8.26 8.2555 1.0 3212453 TimTec1_007172 O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc3ccccc3N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F23 mock treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 F24 mock treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G01 compound treatment 0.269 0.0166 0.89 0.8934 1.0 3086996 TimTec1_007173 Cc1cc(C)nc(SCC(=O)C2CC2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G02 compound treatment 0.436 0.184 9.87 9.8676 1.0 1541773 TimTec1_007174 COc1ccc2nc(sc2c1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G03 compound treatment 0.255 0.00262 0.14 0.1411 1.0 1164972 TimTec1_007175 Oc1cccnc1NC(=O)c2c(O)c3cccc4CCn(c2=O)c43 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G04 compound treatment 0.502 0.25 13.41 13.4143 1.0 1545465 TimTec1_007176 CC(C)CC(=O)N1CCN(CC1)C(=O)COc2ccc(cc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G05 compound treatment 0.238 -0.0144 -0.77 -0.7725 -1.0 1921627 TimTec1_007177 OC1CC(N(Cc2ccccc2)C1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G06 compound treatment 0.275 0.0226 1.22 1.2158 1.0 1246123 TimTec1_007178 CC(C)C(=O)Nc1sc(C)c(C)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G07 compound treatment 0.304 0.0516 2.77 2.7742 1.0 1253428 TimTec1_007179 Brc1ccc(cc1)C(=O)CCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G08 compound treatment 0.258 0.00562 0.3 0.3023 1.0 1492540 TimTec1_007180 CCc1ccc(cc1)c2ccc(C(=O)O)n2C=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G09 compound treatment 0.382 0.13 6.97 6.9658 1.0 1193373 TimTec1_007181 O=C(Cn1nnc(n1)c2ccccc2)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G10 compound treatment 0.257 0.00462 0.25 0.2485 1.0 1348653 TimTec1_007182 CN(C)CCOC(=O)c1cc2ccccc2o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G11 compound treatment 0.225 -0.0274 -1.47 -1.4711 -1.0 3212764 TimTec1_007183 CC(C)CSc1ncnc2scc(c3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G12 compound treatment 0.253 6.25E-4 0.03 0.0336 1.0 3087000 TimTec1_007184 CCSc1cc(C)nc(NC(=O)CC)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G13 compound treatment 0.262 0.00962 0.52 0.5172 1.0 3212765 TimTec1_007185 CC1(CC2CC(C)(C)C1)CN2C(=O)c3ccccc3NC(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G14 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1024239 TimTec1_007186 COc1ccc(cc1)C(=O)CCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G15 compound treatment 0.273 0.0206 1.11 1.1083 1.0 1148203 TimTec1_007187 Nc1c(C#N)c(NCC=C)sc1C(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G16 compound treatment 0.336 0.0836 4.49 4.4938 1.0 3087003 TimTec1_007188 O=c1[nH]cnc2c1sc3nc(cc(c4ccccc4)c32)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G17 compound treatment 0.254 0.00162 0.09 0.0873 1.0 1761275 TimTec1_007189 Cc1cccc2cc(CN(Cc3ccccc3)C(=O)c4ccccc4)c(=O)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G18 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1350623 TimTec1_007190 Clc1ccccc1C2CC(=O)NC(=C2C#N)SCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G19 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1434575 TimTec1_007191 CC(SCCc1ccccn1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G20 compound treatment 0.29 0.0376 2.02 2.0219 1.0 1246459 TimTec1_007192 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G21 compound treatment 0.294 0.0416 2.24 2.2368 1.0 1436571 TimTec1_007193 Cc1ccc(cc1)c2cc3nc(cc(N)n3n2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G22 compound treatment 0.258 0.00562 0.3 0.3023 1.0 1384558 TimTec1_007194 Clc1ccccc1NC(=O)C2(CCOCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G23 mock treatment 0.268 0.0156 0.84 0.8397 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 G24 mock treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H01 compound treatment 0.364 0.112 6.0 5.9985 1.0 1215845 TimTec1_007195 Cc1cc(C(=O)OCC(=O)c2cccs2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H02 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1761483 TimTec1_007196 Cc1ccc2[nH]c(=O)c(CN(CC3CCCO3)C(=O)c4ccco4)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H03 compound treatment 0.287 0.0346 1.86 1.8607 1.0 3212766 TimTec1_007197 CC(C)OC(=O)CSc1ncnc2scc(c3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H04 compound treatment 0.241 -0.0114 -0.61 -0.6113 -1.0 3087045 TimTec1_007198 OC(=O)C1(CCCC1)S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H05 compound treatment 0.238 -0.0144 -0.77 -0.7725 -1.0 1782560 TimTec1_007199 O=C(CCNc1n[nH]c(=O)[nH]c1=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H06 compound treatment 0.26 0.00762 0.41 0.4098 1.0 1787855 TimTec1_007200 COc1ccccc1NC(=O)C(Cc2ccc(C)cc2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H07 compound treatment 0.261 0.00862 0.46 0.4635 1.0 3212767 TimTec1_007201 Cc1ccc(N/C=C\2/C3CCC(C)(C2=O)C3(C)C)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H08 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 3212768 TimTec1_007202 CC1(C)CC(CCNCc2ccc3OCOc3c2)(Cc4ccccc4)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H09 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 3087048 TimTec1_007203 CN1CCN(CC1)c2nc(nc3ccccc23)N4CCN(CCO)CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H10 compound treatment 0.33 0.0776 4.17 4.1714 1.0 1914315 TimTec1_007204 CC(=O)N/C(=C\c1ccccc1)/C(=O)Nc2ccc(O)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H11 compound treatment 0.341 0.0886 4.76 4.7625 1.0 1295223 TimTec1_007205 Cc1ccc(cc1)C(=O)c2c(NC(=O)c3ccncc3)sc4CCCCc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H12 compound treatment 0.254 0.00162 0.09 0.0873 1.0 3087050 TimTec1_007206 OC(=O)CSc1ncnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H13 compound treatment 0.256 0.00362 0.19 0.1948 1.0 1660199 TimTec1_007207 CCOc1cc(CN2CCN(CC2)C(=O)CC(C)C)ccc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H14 compound treatment 0.25 -0.00238 -0.13 -0.1276 -1.0 1413084 TimTec1_007208 OC(=O)CSCC(=O)Nc1ccccc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H15 compound treatment 0.271 0.0186 1.0 1.0009 1.0 1396450 TimTec1_007209 COc1ccc(cc1)c2ccc(CCC(=O)O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H16 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 3212769 TimTec1_007210 O=S(=O)(NC1CC2CCC1C2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H17 compound treatment 0.291 0.0386 2.08 2.0756 1.0 1132422 TimTec1_007211 CC(C)CCNC(=O)C1CCN(Cc2cccc(OCc3ccccc3)c2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H18 compound treatment 0.313 0.0606 3.26 3.2579 1.0 1184017 TimTec1_007212 Oc1c(ccc2cccnc12)C(NC(=O)c3ccccc3)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H19 compound treatment 0.448 0.196 10.51 10.5125 1.0 1526246 TimTec1_007213 CCOc1ccc(cc1)c2cn3CCn4cccc4-c3c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H20 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1615914 TimTec1_007214 C(C1CCCCC1)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H21 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 3212770 TimTec1_007215 FC(F)(F)C(=O)N(Cc1ccccc1)C(C(=O)NC2CCCC2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H22 compound treatment 0.238 -0.0144 -0.77 -0.7725 -1.0 1324827 TimTec1_007216 COc1ccc(CNC(C)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H23 mock treatment 0.253 6.25E-4 0.03 0.0336 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 H24 mock treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I01 compound treatment 0.366 0.114 6.11 6.106 1.0 3087054 TimTec1_007217 CCN(CC)C(=O)c1sc2nc(cc(c2c1N)C(F)(F)F)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I02 compound treatment 0.245 -0.00738 -0.4 -0.3963 -1.0 3212771 TimTec1_007218 COc1cccc2cc(C(=O)Nc3ccccc3c4nnn(CC(=O)NC(C)(C)C)n4)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I03 compound treatment 0.266 0.0136 0.73 0.7322 1.0 1785833 TimTec1_007219 CCCNC(=O)c1c(O)c2CCCCc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I04 compound treatment 0.262 0.00962 0.52 0.5172 1.0 1143730 TimTec1_007220 CC1(C)CC(CCO1)(C(CO)CNCc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I05 compound treatment 0.546 0.294 15.78 15.7788 1.0 1623536 TimTec1_007221 OC1=C(COC1=O)C(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I06 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1590931 TimTec1_007222 O=S(=O)(CC(CN1CCCCC1)N2CCCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I07 compound treatment 0.328 0.0756 4.06 4.0639 1.0 1668547 TimTec1_007223 Oc1ccc(cc1)c2cccc(n2)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I08 compound treatment 0.275 0.0226 1.22 1.2158 1.0 1147480 TimTec1_007224 Cc1c(C#N)c(NC(=O)c2cccs2)sc1C(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I09 compound treatment 0.242 -0.0104 -0.56 -0.5575 -1.0 1394770 TimTec1_007225 OCCCc1cn(c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I10 compound treatment 0.536 0.284 15.24 15.2414 1.0 1050975 TimTec1_007226 Cc1ccc(cc1)c2nnc(o2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I11 compound treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1459697 TimTec1_007227 COc1cc(NC(=O)CCN2CCC(C)CC2)cc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I12 compound treatment 0.306 0.0536 2.88 2.8817 1.0 1104871 TimTec1_007228 COC(=O)c1ccc2[n+]([O-])onc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I13 compound treatment 0.276 0.0236 1.27 1.2696 1.0 1491293 TimTec1_007229 COc1ccc2CC(O)c3cc4OCOc4cc3CCN(C)Cc2c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I14 compound treatment 0.437 0.185 9.92 9.9214 1.0 3087121 TimTec1_007230 CC(Oc1ccccc1)C(=O)Nc2nnc(s2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I15 compound treatment 0.336 0.0836 4.49 4.4938 1.0 1557638 TimTec1_007231 O=C(CCN1CCc2ccccc2C1)Nc3ccc4CCCc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I16 compound treatment 0.274 0.0216 1.16 1.1621 1.0 1332636 TimTec1_007232 NC(=O)CC1Sc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I17 compound treatment 0.294 0.0416 2.24 2.2368 1.0 1711213 TimTec1_007233 CN(CCC(=O)Nc1ccc2OCOc2c1)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I18 compound treatment 0.55 0.298 15.99 15.9937 1.0 3212772 TimTec1_007234 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCC2)/C=C/c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I19 compound treatment 0.253 6.25E-4 0.03 0.0336 1.0 3087124 TimTec1_007235 CC1Oc2ccccc2OC1C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I20 compound treatment 0.469 0.217 11.64 11.641 1.0 1059391 TimTec1_007236 N1NC(=NN=C1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I21 compound treatment 0.272 0.0196 1.05 1.0546 1.0 1417338 TimTec1_007237 CCCCN(C)C(=O)C1CCN(Cc2ccc(OCC)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I22 compound treatment 0.389 0.137 7.34 7.3419 1.0 1447122 TimTec1_007238 O=C(COC(=O)c1ccccc1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I23 mock treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 I24 mock treatment 0.26 0.00762 0.41 0.4098 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J01 compound treatment 0.543 0.291 15.62 15.6176 1.0 3087127 TimTec1_007239 O=C(CCCc1ccccc1)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J02 compound treatment 0.255 0.00262 0.14 0.1411 1.0 1381726 TimTec1_007240 CC(C)CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J03 compound treatment 0.26 0.00762 0.41 0.4098 1.0 3087128 TimTec1_007241 O=C(Cc1ccccc1)N2CCN(CC2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J04 compound treatment 0.282 0.0296 1.59 1.592 1.0 3212853 TimTec1_007242 COC(=O)C1=CN(CCc2ccc(OC)cc2)C=C(C1c3ccsc3)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J05 compound treatment 0.384 0.132 7.07 7.0733 1.0 3087130 TimTec1_007243 O=C(NCCC1=CCCCC1)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J06 compound treatment 0.459 0.207 11.1 11.1036 1.0 3212854 TimTec1_007244 Cc1ccc2nc(NC(=O)C(F)(F)F)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J07 compound treatment 0.261 0.00862 0.46 0.4635 1.0 3212855 TimTec1_007245 O=C(CC1CC2CCC1C2)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J08 compound treatment 0.288 0.0356 1.91 1.9144 1.0 3087132 TimTec1_007246 CCCC(C)C(=O)Nc1nnc(s1)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J09 compound treatment 0.246 -0.00638 -0.34 -0.3426 -1.0 1343394 TimTec1_007247 Cc1ccc(cc1)c2ccc(CCC(=O)O)[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J10 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 3087133 TimTec1_007248 CN(C)c1ccc(cc1)C(CC=C)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J11 compound treatment 0.267 0.0146 0.79 0.7859 1.0 1169499 TimTec1_007249 CC(C)CNC(=O)c1ccc(Br)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J12 compound treatment 0.281 0.0286 1.54 1.5382 1.0 1620830 TimTec1_007250 NS(=O)(=O)c1cccc(c1)C(=O)NCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J13 compound treatment 0.483 0.231 12.39 12.3933 1.0 1204293 TimTec1_007251 Nc1ncnc2[nH]c(SCc3nc4ccccc4n3Cc5ccccc5)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J14 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1737852 TimTec1_007252 OC(=O)c1ccc(cc1)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J15 compound treatment 0.503 0.251 13.47 13.4681 1.0 3212856 TimTec1_007253 CCCC(C)C(=O)Nc1nnc(Cc2ccc(OC)cc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J16 compound treatment 0.266 0.0136 0.73 0.7322 1.0 1787669 TimTec1_007254 OC(COCC1CCC=CC1)CN(Cc2ccccc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J17 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1458427 TimTec1_007255 Oc1ccc(CN2CCCCC2)nc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J18 compound treatment 0.271 0.0186 1.0 1.0009 1.0 1535978 TimTec1_007256 Oc1ccc2ccccc2c1C(NC(=O)CCc3ccccc3)c4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J19 compound treatment 0.488 0.236 12.66 12.662 1.0 1729058 TimTec1_007257 CCOC(=O)c1c[nH]c2c(cccc2c1=O)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J20 compound treatment 0.461 0.209 11.21 11.2111 1.0 1266090 TimTec1_007258 O=C(N1CCN(CC1)c2ncnc3sc4CCCCc4c23)c5ccco5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J21 compound treatment 0.253 6.25E-4 0.03 0.0336 1.0 1722077 TimTec1_007259 OC(=O)C1CNC(S1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J22 compound treatment 0.459 0.207 11.1 11.1036 1.0 1633478 TimTec1_007260 OC(=O)c1c(NC(=O)c2ccc(F)cc2)scc1c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J23 mock treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 J24 mock treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K01 compound treatment 0.445 0.193 10.35 10.3513 1.0 3087134 TimTec1_007261 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K02 compound treatment 0.26 0.00762 0.41 0.4098 1.0 3212857 TimTec1_007262 Cc1cnc(cn1)C(=O)Nc2ccccc2c3nnn(CC(=O)NC4CCCC4)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K03 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1132974 TimTec1_007263 CC1CCCN(C1)C(=O)C2CCN(CC3CCCCC3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K04 compound treatment 0.256 0.00362 0.19 0.1948 1.0 3212858 TimTec1_007264 COC(=O)C1C(C(=C(CC1(C)O)Nc2ccc(C)cc2)C(=O)OC)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K05 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 1418415 TimTec1_007265 COc1ccc(cc1OC)C(C)N(C)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K06 compound treatment 0.241 -0.0114 -0.61 -0.6113 -1.0 1367310 TimTec1_007266 OC(=O)C1CN(C(=O)C1)c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K07 compound treatment 0.296 0.0436 2.34 2.3443 1.0 1749464 TimTec1_007267 COC(=O)c1cccc(NC(=O)c2cnccn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K08 compound treatment 0.474 0.222 11.91 11.9097 1.0 1509871 TimTec1_007268 CCC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K09 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1244693 TimTec1_007269 CCN1CCCC1CNC(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K10 compound treatment 0.416 0.164 8.79 8.7929 1.0 1569404 TimTec1_007270 C1CCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K11 compound treatment 0.563 0.311 16.69 16.6923 1.0 1600050 TimTec1_007271 Brc1ccc(cc1)C(=O)COC(=O)CSc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K12 compound treatment 0.294 0.0416 2.24 2.2368 1.0 1451391 TimTec1_007272 Oc1ccccc1C(CC(=O)NCc2ccccc2)NCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K13 compound treatment 0.242 -0.0104 -0.56 -0.5575 -1.0 1622555 TimTec1_007273 COC(C(=O)NCc1ccc(C)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K14 compound treatment 0.267 0.0146 0.79 0.7859 1.0 1244048 TimTec1_007274 OC(=O)C1(CCC(C1)Nc2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K15 compound treatment 0.407 0.155 8.31 8.3092 1.0 1530042 TimTec1_007275 O=C(CCC1CCCC1)N2CCN(CC2)C(=O)COc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K16 compound treatment 0.286 0.0336 1.81 1.8069 1.0 1301695 TimTec1_007276 O=C(NCc1ccccc1)c2ccc(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K17 compound treatment 0.374 0.122 6.54 6.5359 1.0 3087135 TimTec1_007277 FC(F)(F)c1cc(nc2cc(nn12)C(=O)N3CCSCC3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K18 compound treatment 0.399 0.147 7.88 7.8793 1.0 1164653 TimTec1_007278 Clc1ccc(NC(=O)CN(Cc2ccco2)C(=O)c3ccccc3)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K19 compound treatment 0.386 0.134 7.18 7.1807 1.0 3087136 TimTec1_007279 CC(=O)Nc1nc(C)c(Cc2ccccc2)c(O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K20 compound treatment 0.285 0.0326 1.75 1.7532 1.0 3212859 TimTec1_007280 COc1cc2CCN(C3CC4(C=CC(=O)C=C4)c(c32)c1OC)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K21 compound treatment 0.274 0.0216 1.16 1.1621 1.0 1585233 TimTec1_007281 COc1ccc(cc1)C2N(CC=C)C(=O)C(=C2C(=O)c3ccccc3)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K22 compound treatment 0.254 0.00162 0.09 0.0873 1.0 3087182 TimTec1_007282 CC(C)CCNCC1OCc2ccccc2CO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K23 mock treatment 0.257 0.00462 0.25 0.2485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 K24 mock treatment 0.255 0.00262 0.14 0.1411 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L01 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 1537215 TimTec1_007283 S=c1n(CN2CCOCC2)nnn1C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L02 compound treatment 0.266 0.0136 0.73 0.7322 1.0 1303821 TimTec1_007284 COC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(O)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L03 compound treatment 0.269 0.0166 0.89 0.8934 1.0 3087183 TimTec1_007285 COc1cccc(OC)c1C(=O)Nc2nnc(CC(C)(C)C)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L04 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 3087184 TimTec1_007286 CCN(CC)Cc1c(CC(C)C)oc(C)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L05 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 3087185 TimTec1_007287 O=C(N1CCCCC1)c2ccc3snnc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L06 compound treatment 0.302 0.0496 2.67 2.6667 1.0 1320337 TimTec1_007288 Cc1ccc(NC(=O)CNc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L07 compound treatment 0.276 0.0236 1.27 1.2696 1.0 3087186 TimTec1_007289 Cc1cccc2cc(C(N(Cc3ccco3)Cc4ccccc4)c5nnnn5C(C)(C)C)c(=O)[nH]c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L08 compound treatment 0.253 6.25E-4 0.03 0.0336 1.0 1784505 TimTec1_007290 Cc1ccc(cc1)n2nc-3c(CCc4nonc43)[n+]2[O-] 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L09 compound treatment 0.25 -0.00238 -0.13 -0.1276 -1.0 1715611 TimTec1_007291 CC(C)c1ccc(cc1)N2CC(CC2=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L10 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 3212860 TimTec1_007292 FC(F)(F)C(=O)N(Cc1ccc2OCOc2c1)C(C(=O)NC3CCCCC3)c4ccccn4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L11 compound treatment 0.354 0.102 5.46 5.4611 1.0 1196884 TimTec1_007293 CCCn1c(=O)c(c(O)c2ccccc12)c3nc4ccccc4c(=O)[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L12 compound treatment 0.277 0.0246 1.32 1.3233 1.0 1066059 TimTec1_007294 CN1C(CC(=O)CC1c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L13 compound treatment 0.281 0.0286 1.54 1.5382 1.0 1212761 TimTec1_007295 CC1(C)OC(=O)N(c2ccccc2)C31Oc4cc5ccccc5cc4C=C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L14 compound treatment 0.287 0.0346 1.86 1.8607 1.0 3087187 TimTec1_007296 CC(C)N(C(C)C)c1nnc(N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L15 compound treatment 0.255 0.00262 0.14 0.1411 1.0 3212861 TimTec1_007297 CCN(CC)CCCNc1ncnc2sc3CCC(C)Cc3c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L16 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1625654 TimTec1_007298 C(CN1C2CCC1C=CC2)N3C4CCC3C=CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L17 compound treatment 0.258 0.00562 0.3 0.3023 1.0 3212862 TimTec1_007299 FC(F)(F)C(=O)NCc1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L18 compound treatment 0.315 0.0626 3.37 3.3653 1.0 3212863 TimTec1_007300 COC(=O)c1cc(no1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L19 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1270867 TimTec1_007301 CCCC(CCC)C(=O)NC1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L20 compound treatment 0.254 0.00162 0.09 0.0873 1.0 3212864 TimTec1_007302 OC(=O)CN1C(=O)CSc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L21 compound treatment 0.257 0.00462 0.25 0.2485 1.0 1632361 TimTec1_007303 CC(=O)Nc1cccc(c1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L22 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 3087188 TimTec1_007304 Nc1nc2ccc(CC(=O)O)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L23 mock treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 L24 mock treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M01 compound treatment 0.334 0.0816 4.39 4.3864 1.0 3211168 TimTec1_007305 Brc1ccc(N/C=C\2/Sc3ccccc3C2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M02 compound treatment 0.338 0.0856 4.6 4.6013 1.0 3087189 TimTec1_007306 Clc1ccc2nc(nc(c3ccccc3)c2c1)n4nc5ccccc5n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M03 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 1413726 TimTec1_007307 CC1CCN(CC1)C(=O)C2CCN(CC3CCCCC3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M04 compound treatment 0.28 0.0276 1.48 1.4845 1.0 3087190 TimTec1_007308 O=C(CCC1CCCC1)N2CCN(CC3CCC=CC3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M05 compound treatment 0.464 0.212 11.37 11.3723 1.0 3211169 TimTec1_007309 Cc1cc2nn(nc2cc1NC(=O)c3cccs3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M06 compound treatment 0.23 -0.0224 -1.2 -1.2024 -1.0 1787986 TimTec1_007310 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M07 compound treatment 0.534 0.282 15.13 15.1339 1.0 1163680 TimTec1_007311 O=C1C(=C(C#N)c2nc3ccccc3[nH]2)C(=O)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M08 compound treatment 0.482 0.23 12.34 12.3396 1.0 1392143 TimTec1_007312 CC(C)C(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M09 compound treatment 0.293 0.0406 2.18 2.1831 1.0 1649591 TimTec1_007313 COc1ccccc1N2CCN(Cc3ccc(SC)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M10 compound treatment 0.357 0.105 5.62 5.6223 1.0 1308504 TimTec1_007314 CN(C)C(=O)COc1ccc2c(C)cc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M11 compound treatment 0.244 -0.00838 -0.45 -0.4501 -1.0 1709084 TimTec1_007315 Cc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M12 compound treatment 0.266 0.0136 0.73 0.7322 1.0 3087191 TimTec1_007316 CN(C)CCCNc1ncnc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M13 compound treatment 0.246 -0.00638 -0.34 -0.3426 -1.0 3211170 TimTec1_007317 CN(Cc1c(C)nn(C)c1C)C(=O)c2cnn3C(CC(Nc23)c4ccccc4)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M14 compound treatment 0.281 0.0286 1.54 1.5382 1.0 1229927 TimTec1_007318 O=C(NC1CS(=O)(=O)CC1NCc2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M15 compound treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1657371 TimTec1_007319 COc1ccc(CCN(C)CCC(=O)Nc2c(C)cc(C)cc2C)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M16 compound treatment 0.499 0.247 13.25 13.2531 1.0 1600235 TimTec1_007320 COc1ccc(cc1)c2cc(c3ccco3)c(C#N)c(N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M17 compound treatment 0.304 0.0516 2.77 2.7742 1.0 3087192 TimTec1_007321 Cc1sc2ncnc(SCC(=O)c3ccccc3)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M18 compound treatment 0.273 0.0206 1.11 1.1083 1.0 3211171 TimTec1_007322 Oc1ccccc1/C=N/c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M19 compound treatment 0.324 0.0716 3.85 3.849 1.0 1238816 TimTec1_007323 NC1=C(C(=O)CN1C2CCCCC2)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M20 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1918338 TimTec1_007324 CC1(C)CC(=O)C=C(C1)NCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M21 compound treatment 0.279 0.0266 1.43 1.4308 1.0 1143746 TimTec1_007325 CC(=O)Nc1cc(nn1Cc2ccc(Cl)cc2)c3ccc(Br)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M22 compound treatment 0.245 -0.00738 -0.4 -0.3963 -1.0 3211172 TimTec1_007326 CC(=C)CC(Nc1ccc(C)cc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M23 mock treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 M24 mock treatment 0.257 0.00462 0.25 0.2485 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N01 compound treatment 0.273 0.0206 1.11 1.1083 1.0 1282781 TimTec1_007327 OC(COCc1ccc2OCOc2c1)CN3CCN(CC3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N02 compound treatment 0.262 0.00962 0.52 0.5172 1.0 1422214 TimTec1_007328 OCCN1CCN(CC1)C(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N03 compound treatment 0.395 0.143 7.66 7.6644 1.0 3211173 TimTec1_007329 CC(C)OC(=O)CCc1nc2ccccc2nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N04 compound treatment 0.387 0.135 7.23 7.2345 1.0 1325424 TimTec1_007330 NS(=O)(=O)c1ccc(cc1)N2CCCC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N05 compound treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1492718 TimTec1_007331 CCn1c(N)nc2n(C)c(=O)[nH]c(=O)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N06 compound treatment 0.243 -0.00938 -0.5 -0.5038 -1.0 1327606 TimTec1_007332 Cc1oc(c(CO)c1C(=O)O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N07 compound treatment 0.457 0.205 11.0 10.9961 1.0 3211174 TimTec1_007333 CC(C)C(=O)Nc1ccc(cc1)c2nc3cc(NC(=O)C(C)C)ccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N08 compound treatment 0.28 0.0276 1.48 1.4845 1.0 1130123 TimTec1_007334 Cc1ccc2nc(O)c(CCC(=O)O)c(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N09 compound treatment 0.33 0.0776 4.17 4.1714 1.0 1553061 TimTec1_007335 C(N1CCOCC1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N10 compound treatment 0.346 0.0936 5.03 5.0312 1.0 1761372 TimTec1_007336 Cc1ccc2cc(CN(Cc3ccccc3)C(=O)c4ccccc4C)c(=O)[nH]c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N11 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1409640 TimTec1_007337 OC(=O)C1(CCC(=O)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N12 compound treatment 0.236 -0.0164 -0.88 -0.88 -1.0 3211175 TimTec1_007338 CC1(C)CC(CC(C)(C)N1)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N13 compound treatment 0.276 0.0236 1.27 1.2696 1.0 3211176 TimTec1_007339 COc1cccc(C(=O)N2CCN(Cc3ccccc3C(F)(F)F)CC2)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N14 compound treatment 0.241 -0.0114 -0.61 -0.6113 -1.0 3087193 TimTec1_007340 COC(=O)CN1C(=O)COc2ccc(C)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N15 compound treatment 0.444 0.192 10.3 10.2975 1.0 1267449 TimTec1_007341 CC(C)Cc1ccc2c(N)c(sc2n1)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N16 compound treatment 0.266 0.0136 0.73 0.7322 1.0 3211177 TimTec1_007342 Cc1cc(Cl)ccc1OCCCC(=O)Nc2ccccc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N17 compound treatment 0.357 0.105 5.62 5.6223 1.0 1220509 TimTec1_007343 N(c1ccccc1)c2nc(Nc3ccccc3)nc(Oc4ccccc4)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N18 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 1849790 TimTec1_007344 O=C(COC(=O)c1ccco1)NC2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N19 compound treatment 0.259 0.00662 0.36 0.356 1.0 3087194 TimTec1_007345 O=S1(=O)C=C(N2CCOCC2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N20 compound treatment 0.232 -0.0204 -1.09 -1.0949 -1.0 1673885 TimTec1_007346 COCC(C)NCc1cccc(Br)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N21 compound treatment 0.428 0.176 9.44 9.4377 1.0 3211178 TimTec1_007347 O=C(CCCc1c[nH]c2ccccc12)N3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N22 compound treatment 0.254 0.00162 0.09 0.0873 1.0 1139076 TimTec1_007348 CC1CC(c2ccccc2)n3ncnc3N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N23 mock treatment 0.237 -0.0154 -0.83 -0.8262 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 N24 mock treatment 0.247 -0.00538 -0.29 -0.2888 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O01 compound treatment 0.44 0.188 10.08 10.0826 1.0 1243484 TimTec1_007349 CC(C)C(=O)NC(c1ccc2cccnc2c1O)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O02 compound treatment 0.329 0.0766 4.12 4.1177 1.0 1718539 TimTec1_007350 O=C(CC1CCCCC1)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O03 compound treatment 0.259 0.00662 0.36 0.356 1.0 3211179 TimTec1_007351 COc1ccc(cc1)c2cc(n3ncc(C(=O)NC(C)(C)C)c3n2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O04 compound treatment 0.269 0.0166 0.89 0.8934 1.0 1737590 TimTec1_007352 COc1ccc(CN2CCN(Cc3cccc4ccccc34)CC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O05 compound treatment 0.256 0.00362 0.19 0.1948 1.0 3087195 TimTec1_007353 CC(NC(=O)C1C2CC(C)(NC1=O)Oc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O06 compound treatment 0.412 0.16 8.58 8.5779 1.0 1548745 TimTec1_007354 CC(OC(=O)c1ccc(NC(=O)Cc2ccccc2)cc1)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O07 compound treatment 0.237 -0.0154 -0.83 -0.8262 -1.0 3087196 TimTec1_007355 CC(Sc1nc(C)cc(C)n1)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O08 compound treatment 0.421 0.169 9.06 9.0616 1.0 3211180 TimTec1_007356 Cc1cc(=O)oc2[nH]nc(c3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O09 compound treatment 0.249 -0.00338 -0.18 -0.1814 -1.0 1303989 TimTec1_007357 C(OC(CN1CCCC1)CN2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O10 compound treatment 0.266 0.0136 0.73 0.7322 1.0 1593421 TimTec1_007358 NC(=O)c1ccc2[nH]c3CCCCc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O11 compound treatment 0.277 0.0246 1.32 1.3233 1.0 3211181 TimTec1_007359 Nc1nc(NC(=O)c2ccco2)nn1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O12 compound treatment 0.254 0.00162 0.09 0.0873 1.0 1296021 TimTec1_007360 COc1ccc(cc1)C(=O)N2CCN(CC2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O13 compound treatment 0.253 6.25E-4 0.03 0.0336 1.0 1153011 TimTec1_007361 CC1CCN(CC1)C(=O)CCCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O14 compound treatment 0.258 0.00562 0.3 0.3023 1.0 1079167 TimTec1_007362 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4Cl)C(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O15 compound treatment 0.278 0.0256 1.38 1.377 1.0 1388332 TimTec1_007363 CNC(=O)c1c(O)c2ccccc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O16 compound treatment 0.422 0.17 9.12 9.1153 1.0 3211244 TimTec1_007364 O/N=C/c1c(OCc2ccccc2)ccc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O17 compound treatment 0.271 0.0186 1.0 1.0009 1.0 1449392 TimTec1_007365 CCN(CC)c1ccc(CC(=O)NC(C)Cc2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O18 compound treatment 0.274 0.0216 1.16 1.1621 1.0 1229289 TimTec1_007366 CCc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccccc4C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O19 compound treatment 0.419 0.167 8.95 8.9541 1.0 1499628 TimTec1_007367 OC(CNc1nc2ccccc2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O20 compound treatment 0.377 0.125 6.7 6.6971 1.0 1146614 TimTec1_007368 O=C(CC1CCCCC1)Nc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O21 compound treatment 0.287 0.0346 1.86 1.8607 1.0 1429365 TimTec1_007369 CCOc1ccc(Nc2nc3c(C)cccc3cc2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O22 compound treatment 0.26 0.00762 0.41 0.4098 1.0 1134013 TimTec1_007370 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccc(F)c4)C(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O23 mock treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 O24 mock treatment 0.254 0.00162 0.09 0.0873 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P01 compound treatment 0.263 0.0106 0.57 0.571 1.0 1386295 TimTec1_007371 CC(C)(C)C(=O)N1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P02 compound treatment 0.374 0.122 6.54 6.5359 1.0 3087246 TimTec1_007372 O=C(CSc1ncnc2sc3CCCCc3c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P03 compound treatment 0.311 0.0586 3.15 3.1504 1.0 3087247 TimTec1_007373 Oc1cc(nn1c2nc3ccccc3s2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P04 compound treatment 0.258 0.00562 0.3 0.3023 1.0 1158378 TimTec1_007374 O=C(C(c1ccccc1)c2ccccc2)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P05 compound treatment 0.409 0.157 8.42 8.4167 1.0 1653550 TimTec1_007375 O=C(Cc1cccs1)Nc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P06 compound treatment 0.41 0.158 8.47 8.4704 1.0 3211245 TimTec1_007376 CCOC(=O)COc1nc(cc(n1)C(F)(F)F)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P07 compound treatment 0.239 -0.0134 -0.72 -0.7187 -1.0 1544065 TimTec1_007377 COc1cc2CN(C)CC3(CCC(O)CC3)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P08 compound treatment 0.242 -0.0104 -0.56 -0.5575 -1.0 3211246 TimTec1_007378 Cc1nc(N)nc(C)c1Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P09 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 3087248 TimTec1_007379 COC(=O)Cn1nc(c2CCCCc21)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P10 compound treatment 0.25 -0.00238 -0.13 -0.1276 -1.0 3211247 TimTec1_007380 COC(=O)c1ccc(CN2CCN(Cc3ccc(o3)C(=O)OC)CC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P11 compound treatment 0.47 0.218 11.69 11.6947 1.0 1443632 TimTec1_007381 Fc1ccc(OCC(=O)Nc2ccc(cc2)n3cnnn3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P12 compound treatment 0.248 -0.00438 -0.24 -0.2351 -1.0 1599989 TimTec1_007382 COc1cc(cc(OC)c1OC)c2cc(C#N)on2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P13 compound treatment 0.383 0.131 7.02 7.0195 1.0 1535300 TimTec1_007383 CC1(O)N(CCc2cccc3ccccc23)C(=O)c4ccccc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P14 compound treatment 0.233 -0.0194 -1.04 -1.0412 -1.0 1782858 TimTec1_007384 CCC(C)(Nc1n[nH]c(=O)[nH]c1=O)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P15 compound treatment 0.335 0.0826 4.44 4.4401 1.0 1583688 TimTec1_007385 OC(=O)C1CCCc2c1[nH]c3ccc(Cl)cc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P16 compound treatment 0.237 -0.0154 -0.83 -0.8262 -1.0 1183239 TimTec1_007386 CC(C)c1nc2ccccc2n1CC(C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P17 compound treatment 0.246 -0.00638 -0.34 -0.3426 -1.0 3211371 TimTec1_007387 O=C(CC1CC2CCC1C2)N(C(C(=O)NC3CCCCC3)c4cccs4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P18 compound treatment 0.242 -0.0104 -0.56 -0.5575 -1.0 1248349 TimTec1_007388 OC(=O)C1CCCN1C(=O)c2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P19 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1705108 TimTec1_007389 CC(C)Oc1ccc(cc1)C(CC(=O)N)CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P20 compound treatment 0.436 0.184 9.87 9.8676 1.0 1182227 TimTec1_007390 Clc1cccc(NCCC(=O)c2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P21 compound treatment 0.241 -0.0114 -0.61 -0.6113 -1.0 3211372 TimTec1_007391 CC1=CCC(C(C1)C(=O)NC2CCCCC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P22 compound treatment 0.24 -0.0124 -0.67 -0.665 -1.0 1251182 TimTec1_007392 COCC(C)NCc1cccc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P23 mock treatment 0.251 -0.00138 -0.07 -0.0739 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2083 P24 mock treatment 0.252 -3.75E-4 -0.02 -0.0202 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A01 compound treatment 0.273 0.0211 1.14 1.1352 1.0 3211373 TimTec1_007393 CC(C)C(=O)N1CCN(CC1)c2ccccc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A02 compound treatment 0.453 0.201 10.81 10.808 1.0 1229675 TimTec1_007394 COc1ccccc1CC(=O)Nc2nncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A03 compound treatment 0.51 0.258 13.87 13.8711 1.0 3087249 TimTec1_007395 COc1cc2[nH]c(NC(=O)c3ccc(Cl)cc3)nc(=O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A04 compound treatment 0.232 -0.0199 -1.07 -1.068 -1.0 1648941 TimTec1_007396 CC(=O)Nc1ccccc1C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A05 compound treatment 0.281 0.0291 1.57 1.5651 1.0 3087250 TimTec1_007397 CN1CCC(CC1)OC(=O)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A06 compound treatment 0.262 0.0101 0.54 0.5441 1.0 3211374 TimTec1_007398 CCOc1ccc(cc1)C(=O)OCC(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A07 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 1229195 TimTec1_007399 OC(=O)c1cc(NC(=O)Cc2ccccc2)ccc1N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A08 compound treatment 0.583 0.331 17.79 17.794 1.0 3087251 TimTec1_007400 CCc1ccc(OCC(=O)N2CCc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A09 compound treatment 0.497 0.245 13.17 13.1725 1.0 3211375 TimTec1_007401 CCNc1oc(COc2ccc(OC)cc2)nc1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A10 compound treatment 0.235 -0.0169 -0.91 -0.9068 -1.0 3087252 TimTec1_007402 COCc1[nH]nc2OC(=C(C#N)C3(C(=O)Nc4ccccc43)c12)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A11 compound treatment 0.257 0.00512 0.28 0.2754 1.0 3211376 TimTec1_007403 C=CCOc1ccccc1CNc2nc[nH]n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A12 compound treatment 0.499 0.247 13.28 13.28 1.0 3211377 TimTec1_007404 CN(C)c1oc(nc1C#N)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A13 compound treatment 0.259 0.00712 0.38 0.3829 1.0 3087253 TimTec1_007405 COc1cc(OC)cc(OCC(O)Cn2ccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A14 compound treatment 0.263 0.0111 0.6 0.5978 1.0 3211378 TimTec1_007406 CC(Oc1ccccc1F)C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A15 compound treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 3551464 TimTec1_007407 OC12CCCCC2C(NCC1)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A16 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 1438511 TimTec1_007408 COc1cc(cc(OC)c1OC)C(=O)N2CCN(CC2)C(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A17 compound treatment 0.501 0.249 13.39 13.3875 1.0 3211379 TimTec1_007409 CCn1nnc(NC(=O)c2sc3ccccc3c2Cl)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A18 compound treatment 0.355 0.103 5.54 5.5417 1.0 3211380 TimTec1_007410 COc1cccc(NC(=O)Cn2c(nc3ccccc23)c4cncs4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A19 compound treatment 0.284 0.0321 1.73 1.7263 1.0 3087254 TimTec1_007411 COC(=O)c1cn(CC(=O)NCc2ccc3OCOc3c2)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A20 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3211381 TimTec1_007412 Cc1ccccc1C(=O)Nc2c(C)nc(O)nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A21 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3087255 TimTec1_007413 Cc1sc2ncnc(N3CCN(CCO)CC3)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A22 compound treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 1416150 TimTec1_007414 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc(Cl)c3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A23 mock treatment 0.252 1.25E-4 0.01 0.0067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 A24 mock treatment 0.265 0.0131 0.71 0.7053 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B01 compound treatment 0.408 0.156 8.39 8.3898 1.0 1286008 TimTec1_007415 Cc1nc(C)c(s1)c2csc(Nc3cccc(C)c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B02 compound treatment 0.341 0.0891 4.79 4.7894 1.0 3211382 TimTec1_007416 Clc1ccc(cc1)C2SC(=O)NC3=C2C(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B03 compound treatment 0.254 0.00212 0.11 0.1142 1.0 1624823 TimTec1_007417 CN1CCN(Cc2ccc(O)c3ncccc23)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B04 compound treatment 0.47 0.218 11.72 11.7216 1.0 1292705 TimTec1_007418 COc1ccc(CC(=O)Nc2cc(C)on2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B05 compound treatment 0.325 0.0731 3.93 3.9296 1.0 3087256 TimTec1_007419 Cc1occc1C(=O)Nc2ccc(OCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B06 compound treatment 0.294 0.0421 2.26 2.2637 1.0 1651373 TimTec1_007420 COc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B07 compound treatment 0.337 0.0851 4.57 4.5744 1.0 3211383 TimTec1_007421 CC(Oc1ccc(Cl)cc1Cl)C(=O)NCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B08 compound treatment 0.41 0.158 8.5 8.4973 1.0 3087257 TimTec1_007422 CCC(=O)Nc1nc2ccc(C)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B09 compound treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 3211384 TimTec1_007423 CCOc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B10 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 3087258 TimTec1_007424 CN(C1CCCCC1)c2c[nH]c(=O)[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B11 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3211385 TimTec1_007425 O=C(Cc1ccccc1)NCCN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B12 compound treatment 0.324 0.0721 3.88 3.8758 1.0 1417865 TimTec1_007426 CC(C)C(=O)Nc1scc(c1C(=O)O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B13 compound treatment 0.274 0.0221 1.19 1.189 1.0 1861875 TimTec1_007427 O=C(Nc1ccccc1N2CCCC2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B14 compound treatment 0.285 0.0331 1.78 1.7801 1.0 3087259 TimTec1_007428 C=CCn1c(nc2ccccc12)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B15 compound treatment 0.27 0.0181 0.97 0.974 1.0 3211460 TimTec1_007429 CC(C)c1ccc(NC(=O)C2CC(=O)N=C(N)S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B16 compound treatment 0.438 0.186 10.0 10.002 1.0 3211461 TimTec1_007430 C(Oc1cccc2ccccc12)c3nc(no3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B17 compound treatment 0.296 0.0441 2.37 2.3712 1.0 3087260 TimTec1_007431 CCN(C(=O)Cn1cc(C(=O)C2CC2)c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B18 compound treatment 0.268 0.0161 0.87 0.8665 1.0 1228419 TimTec1_007432 COc1ccccc1Nc2nc(c3ccccc3)c4cc(Cl)ccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B19 compound treatment 0.349 0.0971 5.22 5.2193 1.0 1437567 TimTec1_007433 CC(C)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B20 compound treatment 0.256 0.00412 0.22 0.2217 1.0 3211462 TimTec1_007434 CC1=C(C)CC(C(C1)C(=O)O)C(=O)Nc2cccc(C)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B21 compound treatment 0.413 0.161 8.66 8.6585 1.0 3211463 TimTec1_007435 Cc1nc(NC2=NCCC(=O)N2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B22 compound treatment 0.35 0.0981 5.27 5.273 1.0 1158692 TimTec1_007436 CC(C)NC(=O)c1ccc2ccccc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B23 mock treatment 0.248 -0.00388 -0.21 -0.2082 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 B24 mock treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C01 compound treatment 0.269 0.0171 0.92 0.9203 1.0 3211464 TimTec1_007437 COc1ccc(cc1)c2nc(O)c3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C02 compound treatment 0.477 0.225 12.1 12.0977 1.0 1154391 TimTec1_007438 CCOc1ccccc1C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C03 compound treatment 0.236 -0.0159 -0.85 -0.8531 -1.0 3211465 TimTec1_007439 Cc1ccc2nc(Nc3nccc(C)n3)nc(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C04 compound treatment 0.263 0.0111 0.6 0.5978 1.0 3087261 TimTec1_007440 Cc1nc2ccccc2c(=O)n1c3nc4ccccc4n3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C05 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3211466 TimTec1_007441 CN1CCC(CC1)OC(=O)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C06 compound treatment 0.403 0.151 8.12 8.1211 1.0 3211467 TimTec1_007442 COCc1nnc(NC(=O)Cc2ccccc2)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C07 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 3211468 TimTec1_007443 OC(=O)C1CCCCC1C(=O)Nc2ccc(cc2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C08 compound treatment 0.509 0.257 13.82 13.8174 1.0 3087262 TimTec1_007444 Cc1cccc(C)c1OCC(=O)N2CCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C09 compound treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 1195541 TimTec1_007445 CCN(CC)CCCN1C(C(=C(O)C1=O)C(=O)c2cc(C)ccc2C)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C10 compound treatment 0.24 -0.0119 -0.64 -0.6381 -1.0 1658976 TimTec1_007446 OC(=O)C1CCCCC1C(=O)Nc2cccc(F)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C11 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3211469 TimTec1_007447 COC(=O)c1cn(CC(=O)N2CCCCC2C)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C12 compound treatment 0.512 0.26 13.98 13.9786 1.0 1699768 TimTec1_007448 Cc1ccc(cc1)S(=O)(=O)c2nc(sc2Cl)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C13 compound treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 3211470 TimTec1_007449 CCc1cccc2c(C#N)cn(CC(=O)NC3CCCC3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C14 compound treatment 0.269 0.0171 0.92 0.9203 1.0 3087263 TimTec1_007450 Cc1ccc(C)c(c1)C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C15 compound treatment 0.286 0.0341 1.83 1.8338 1.0 3087311 TimTec1_007451 COc1ccccc1N2CCN(CC2)C(=O)CC(C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C16 compound treatment 0.259 0.00712 0.38 0.3829 1.0 1347933 TimTec1_007452 Clc1cccc(CN2CCN(Cc3ccco3)CC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C17 compound treatment 0.337 0.0851 4.57 4.5744 1.0 3087312 TimTec1_007453 CC(Oc1ccc(Cl)cc1Cl)C(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C18 compound treatment 0.288 0.0361 1.94 1.9413 1.0 3087313 TimTec1_007454 Cc1ccccc1Cn2c(nc3ccccc23)c4cncs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C19 compound treatment 0.263 0.0111 0.6 0.5978 1.0 3087314 TimTec1_007455 Nc1[nH]c(SCC(=O)N2CCCC2)nc(=O)c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C20 compound treatment 0.263 0.0111 0.6 0.5978 1.0 3087315 TimTec1_007456 FC(F)(F)c1nc2cc3[nH]c(=O)[nH]c3cc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C21 compound treatment 0.318 0.0661 3.55 3.5534 1.0 3087316 TimTec1_007457 CCc1cc2c(NCC3CCCO3)nc(C)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C22 compound treatment 0.27 0.0181 0.97 0.974 1.0 3087317 TimTec1_007458 Cc1ccc(C)c(OCCCN2CCNCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C23 mock treatment 0.256 0.00412 0.22 0.2217 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 C24 mock treatment 0.252 1.25E-4 0.01 0.0067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D01 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3211471 TimTec1_007459 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)C(=O)OC)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D02 compound treatment 0.365 0.113 6.08 6.0791 1.0 3087318 TimTec1_007460 Cc1ccnc(Nc2nc3ccccc3s2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D03 compound treatment 0.449 0.197 10.59 10.5931 1.0 3211472 TimTec1_007461 Cc1cccn2cc(CNc3nc4ccccc4s3)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D04 compound treatment 0.359 0.107 5.76 5.7567 1.0 3211473 TimTec1_007462 OCc1nc2ccccc2n1C/C=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D05 compound treatment 0.273 0.0211 1.14 1.1352 1.0 3087319 TimTec1_007463 COC(=O)c1cn(C(=O)COc2ccccc2Cl)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D06 compound treatment 0.308 0.0561 3.02 3.016 1.0 3211474 TimTec1_007464 COC(=O)CNc1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D07 compound treatment 0.251 -8.75E-4 -0.05 -0.047 -1.0 3087320 TimTec1_007465 Cc1cc(C)c(C)c(OCC(=O)NCC2CCCO2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D08 compound treatment 0.301 0.0491 2.64 2.6399 1.0 1236869 TimTec1_007466 CC(C)N1CC(CC1=O)C(=O)Nc2ccc(Cl)c(Cl)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D09 compound treatment 0.374 0.122 6.56 6.5627 1.0 3087321 TimTec1_007467 C1Oc2ccc(cc2O1)c3nc(no3)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D10 compound treatment 0.307 0.0551 2.96 2.9623 1.0 1259602 TimTec1_007468 CCCn1c(nc2ccccc12)C(=O)c3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D11 compound treatment 0.356 0.104 5.6 5.5955 1.0 3211475 TimTec1_007469 Cc1ccccc1OCC(=O)Nc2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D12 compound treatment 0.32 0.0681 3.66 3.6609 1.0 1684343 TimTec1_007470 O=c1n(cnc2scc(c3cccs3)c12)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D13 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 1861864 TimTec1_007471 CCC(=O)Nc1ccccc1N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D14 compound treatment 0.305 0.0531 2.85 2.8548 1.0 3087322 TimTec1_007472 CC(C)C(=O)NCCc1nc2ccccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D15 compound treatment 0.251 -8.75E-4 -0.05 -0.047 -1.0 3211476 TimTec1_007473 COc1cc(ccc1OCC(=O)N)C2NC(=O)NC(=C2C(=O)NCc3ccccc3)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D16 compound treatment 0.27 0.0181 0.97 0.974 1.0 3087323 TimTec1_007474 Cc1cc(=O)[nH]c(n1)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D17 compound treatment 0.248 -0.00388 -0.21 -0.2082 -1.0 3211477 TimTec1_007475 COc1ccc(OCC(=O)Nc2ccccc2C(=O)N3CCOCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D18 compound treatment 0.313 0.0611 3.28 3.2847 1.0 1603028 TimTec1_007476 Brc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D19 compound treatment 0.291 0.0391 2.1 2.1025 1.0 1256546 TimTec1_007477 CCOC(=O)c1sc(NC=O)c(C(=O)OCC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D20 compound treatment 0.45 0.198 10.65 10.6468 1.0 1296988 TimTec1_007478 Clc1ccc(cc1Cl)C(=O)COC(=O)CCn2nnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D21 compound treatment 0.395 0.143 7.69 7.6912 1.0 3087324 TimTec1_007479 COCc1cc(O)nc(Nc2nc3ccccc3s2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D22 compound treatment 0.373 0.121 6.51 6.509 1.0 3211478 TimTec1_007480 CC(C)C(=O)Nc1cnc2ccccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D23 mock treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 D24 mock treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E01 compound treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 3087325 TimTec1_007481 Cc1cc(C)nc(NC(=N)N2N=CCC2c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E02 compound treatment 0.26 0.00812 0.44 0.4366 1.0 3211479 TimTec1_007482 CCC(CC)c1nnc(NC(=O)c2c(OC)cccc2OC)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E03 compound treatment 0.304 0.0521 2.8 2.8011 1.0 3211480 TimTec1_007483 C(CN1CNC(=NC1)Nc2nc3ccccc3s2)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E04 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 1489932 TimTec1_007484 CC1(C)Cc2c(C#N)c(NC(=O)c3ccccc3)sc2C(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E05 compound treatment 0.264 0.0121 0.65 0.6516 1.0 1191967 TimTec1_007485 CCCc1c(C)nc2c(OC)cccc2c1SCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E06 compound treatment 0.42 0.168 9.03 9.0347 1.0 3087326 TimTec1_007486 COc1cccc(=O)c2c(C)n(C)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E07 compound treatment 0.483 0.231 12.42 12.4202 1.0 3211481 TimTec1_007487 COc1ccc(cc1)C(=O)OCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E08 compound treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 3087327 TimTec1_007488 CCC(CC)C(=O)N1CCN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E09 compound treatment 0.304 0.0521 2.8 2.8011 1.0 3211554 TimTec1_007489 Cc1ccc(o1)C(=O)C2=C(O)C(=O)N(C2c3cccc(OCC=C)c3)c4nnc(C)s4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E10 compound treatment 0.249 -0.00288 -0.15 -0.1545 -1.0 3087328 TimTec1_007490 CCN(CC)Cc1cc(oc1C(=O)O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E11 compound treatment 0.468 0.216 11.61 11.6141 1.0 3211555 TimTec1_007491 Cc1ccc(OCCCn2c(=O)oc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E12 compound treatment 0.475 0.223 11.99 11.9903 1.0 1870617 TimTec1_007492 Cc1nc(NC(=O)c2sc3ccccc3c2Cl)sc1C(=O)OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E13 compound treatment 0.51 0.258 13.87 13.8711 1.0 3087329 TimTec1_007493 COC(=O)c1cn(CCCOc2ccccc2OC)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E14 compound treatment 0.362 0.11 5.92 5.9179 1.0 1875124 TimTec1_007494 COc1ccc(CNC(=O)c2oc3ccccc3c2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E15 compound treatment 0.272 0.0201 1.08 1.0815 1.0 3087330 TimTec1_007495 CCOCC(=O)N1CCN(CC1)c2cccc(C)c2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E16 compound treatment 0.258 0.00612 0.33 0.3291 1.0 1718923 TimTec1_007496 C(N1CCN(CC1)C2CCCCCC2)c3ccc4OCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E17 compound treatment 0.255 0.00312 0.17 0.1679 1.0 1863832 TimTec1_007497 CC(C)(C)NCc1ccccc1OCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E18 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3211556 TimTec1_007498 S(C(c1ccccc1)c2ccccc2)c3nc[nH]n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E19 compound treatment 0.322 0.0701 3.77 3.7684 1.0 3211557 TimTec1_007499 COC(=O)c1cn(CC(=O)NCc2ccco2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E20 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3087331 TimTec1_007500 C(NC(c1ccccc1)c2ccccc2)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E21 compound treatment 0.316 0.0641 3.45 3.4459 1.0 3087332 TimTec1_007501 C1CCC(C1)Nc2ncnc3sc4CCCc4c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E22 compound treatment 0.473 0.221 11.88 11.8828 1.0 1600198 TimTec1_007502 Clc1cc(NCc2ccc3OCOc3c2)ccc1N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E23 mock treatment 0.267 0.0151 0.81 0.8128 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 E24 mock treatment 0.261 0.00912 0.49 0.4904 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F01 compound treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 3211558 TimTec1_007503 CN(C)C(=O)C1=C(C)NC(=O)NC1c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F02 compound treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 3087333 TimTec1_007504 Cc1cc(C)nc(NC2=NC(=O)CC(N2c3cccc(Cl)c3)C(=O)O)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F03 compound treatment 0.565 0.313 16.83 16.8267 1.0 1348377 TimTec1_007505 Cc1cc(C)c(C#N)c(SCC(O)COc2ccc(Cl)cc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F04 compound treatment 0.29 0.0381 2.05 2.0488 1.0 3087334 TimTec1_007506 CC(=C)Cn1c(Cc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F05 compound treatment 0.245 -0.00688 -0.37 -0.3694 -1.0 1458633 TimTec1_007507 Clc1ccc(CC(=O)N2CCN(CC2)C=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F06 compound treatment 0.383 0.131 7.05 7.0464 1.0 3211559 TimTec1_007508 C=CCNC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)N3CCCC3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F07 compound treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 3087335 TimTec1_007509 CC(C)N(C(C)C)C(=O)Cc1cccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F08 compound treatment 0.267 0.0151 0.81 0.8128 1.0 1336201 TimTec1_007510 Oc1c(CN2CCCC2)c(=O)oc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F09 compound treatment 0.45 0.198 10.65 10.6468 1.0 3211560 TimTec1_007511 Cc1cc(C)c2c(n1)sc3c4OC(=C(C#N)C(c5cccc(Cl)c5)c4c(=O)[nH]c32)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F10 compound treatment 0.463 0.211 11.35 11.3454 1.0 3087336 TimTec1_007512 CCC(=O)Nc1ccc2n(cnc2c1)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F11 compound treatment 0.297 0.0451 2.42 2.4249 1.0 3087337 TimTec1_007513 Fc1ccc(OCC(=O)NCCN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F12 compound treatment 0.261 0.00912 0.49 0.4904 1.0 1313563 TimTec1_007514 CC(C)(C)C(=O)Nc1scc(c2cccs2)c1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F13 compound treatment 0.414 0.162 8.71 8.7123 1.0 1443986 TimTec1_007515 CCC(=O)Nc1nc2ccc(OC)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F14 compound treatment 0.245 -0.00688 -0.37 -0.3694 -1.0 1708556 TimTec1_007516 OC(=O)CC1(O)C(=O)N(Cc2ccccc2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F15 compound treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 3211561 TimTec1_007517 CCc1ccc(NC2OC(=O)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F16 compound treatment 0.495 0.243 13.07 13.065 1.0 1594430 TimTec1_007518 COc1ccc(OCC(=O)N2CCN(CC2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F17 compound treatment 0.247 -0.00488 -0.26 -0.262 -1.0 3211562 TimTec1_007519 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F18 compound treatment 0.301 0.0491 2.64 2.6399 1.0 1461764 TimTec1_007520 Brc1ccc2nc(Nc3ccc(cc3)C(=O)N4CCOCC4)nc(c5ccccc5)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F19 compound treatment 0.247 -0.00488 -0.26 -0.262 -1.0 3087338 TimTec1_007521 CC(C)(C)c1ccc(cc1)C(=O)n2cnnc2N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F20 compound treatment 0.298 0.0461 2.48 2.4787 1.0 1738860 TimTec1_007522 Clc1ccc(cc1)C(=O)COC(=O)c2cnccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F21 compound treatment 0.322 0.0701 3.77 3.7684 1.0 3211563 TimTec1_007523 CCN(C(=O)c1ccc(Cl)cc1Cl)c2nnc(s2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F22 compound treatment 0.26 0.00812 0.44 0.4366 1.0 1155556 TimTec1_007524 CC(C)C(=O)Nc1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F23 mock treatment 0.248 -0.00388 -0.21 -0.2082 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 F24 mock treatment 0.245 -0.00688 -0.37 -0.3694 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G01 compound treatment 0.231 -0.0209 -1.12 -1.1218 -1.0 3211564 TimTec1_007525 O=C(NC1=NC2CCCCC2N1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G02 compound treatment 0.423 0.171 9.2 9.1959 1.0 3211565 TimTec1_007526 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2nncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G03 compound treatment 0.238 -0.0139 -0.75 -0.7456 -1.0 3087339 TimTec1_007527 COC(=O)CC1=C(C(NC(=O)N1)c2ccccc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G04 compound treatment 0.377 0.125 6.72 6.724 1.0 1183771 TimTec1_007528 Cc1ccc(OCC(=O)Nc2sc3c(CC(C)(C)NC3(C)C)c2C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G05 compound treatment 0.235 -0.0169 -0.91 -0.9068 -1.0 3211566 TimTec1_007529 CC1CCCC(C1)NCCNC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G06 compound treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 1176872 TimTec1_007530 O=C(Nc1ncnc2sc3CCCCCc3c12)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G07 compound treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 3211567 TimTec1_007531 Cc1nn(C2CCCC2)c3[nH]c(=O)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G08 compound treatment 0.253 0.00112 0.06 0.0605 1.0 1382217 TimTec1_007532 Nc1ccc2n(CCO)c(CO)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G09 compound treatment 0.332 0.0801 4.31 4.3057 1.0 1564264 TimTec1_007533 Cc1oc(cc1COc2ccc(C)cc2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G10 compound treatment 0.249 -0.00288 -0.15 -0.1545 -1.0 3211568 TimTec1_007534 Clc1ccc(NC(=O)C2CN(C3CCCCC3)C(=O)C2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G11 compound treatment 0.288 0.0361 1.94 1.9413 1.0 3087380 TimTec1_007535 CC(C)C(=O)Nc1ncc(Cc2ccccc2Cl)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G12 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 3087381 TimTec1_007536 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G13 compound treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 3087382 TimTec1_007537 OC(=O)C1C(C2CC1C=C2)C(=O)NCCc3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G14 compound treatment 0.319 0.0671 3.61 3.6072 1.0 3087383 TimTec1_007538 O=C(Nc1sc2CCCc2c1C(=O)NCc3ccco3)C4COc5ccccc5O4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G15 compound treatment 0.282 0.0301 1.62 1.6189 1.0 3087384 TimTec1_007539 C1CCC(CC1)c2noc(n2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G16 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3087385 TimTec1_007540 C1CCC(C1)N2CCN(CC2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G17 compound treatment 0.297 0.0451 2.42 2.4249 1.0 1235567 TimTec1_007541 CCOc1cccc(CN(C(=O)C)c2ccc3[nH]c(=O)[nH]c3c2)c1OCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G18 compound treatment 0.516 0.264 14.19 14.1935 1.0 3087386 TimTec1_007542 CC(C)(C)c1nc2C(C(=C(N)Oc2o1)C#N)c3ccc(Cl)cc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G19 compound treatment 0.271 0.0191 1.03 1.0277 1.0 3211569 TimTec1_007543 CC(Nc1nc(nc2ccccc12)N3CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G20 compound treatment 0.278 0.0261 1.4 1.4039 1.0 3087387 TimTec1_007544 CC(NCc1sccc1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G21 compound treatment 0.272 0.0201 1.08 1.0815 1.0 3211570 TimTec1_007545 CC(C)C(=O)Nc1ccc2oc(=O)ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G22 compound treatment 0.302 0.0501 2.69 2.6936 1.0 3087388 TimTec1_007546 Cn1nnc(n1)C(O)CNCc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G23 mock treatment 0.255 0.00312 0.17 0.1679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 G24 mock treatment 0.247 -0.00488 -0.26 -0.262 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H01 compound treatment 0.268 0.0161 0.87 0.8665 1.0 1275919 TimTec1_007547 COc1ccc(CC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H02 compound treatment 0.436 0.184 9.89 9.8945 1.0 3087389 TimTec1_007548 c1cncc(c1)c2nnc(nn2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H03 compound treatment 0.245 -0.00688 -0.37 -0.3694 -1.0 1489991 TimTec1_007549 C(NC1CCN(Cc2ccccc2)CC1)C3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H04 compound treatment 0.479 0.227 12.21 12.2052 1.0 3087390 TimTec1_007550 Cc1cc2ncn(CCOc3ccccc3)c2cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H05 compound treatment 0.308 0.0561 3.02 3.016 1.0 1235475 TimTec1_007551 Cc1ccc(OCC(=O)N2CCCCC2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H06 compound treatment 0.256 0.00412 0.22 0.2217 1.0 3087391 TimTec1_007552 COc1ccc(Cn2c(C)ccc2C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H07 compound treatment 0.256 0.00412 0.22 0.2217 1.0 3211655 TimTec1_007553 O=C(CCC1CCCCC1)NCCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H08 compound treatment 0.491 0.239 12.85 12.8501 1.0 1250277 TimTec1_007554 CSc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H09 compound treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 3087392 TimTec1_007555 NC(=O)Cn1c(=O)n(CC(=O)N)c2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H10 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 1733719 TimTec1_007556 CN(C(=O)CCN1C(=O)C(C)(C)Nc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H11 compound treatment 0.265 0.0131 0.71 0.7053 1.0 3087393 TimTec1_007557 Nc1nc2ccc(cc2s1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H12 compound treatment 0.465 0.213 11.45 11.4529 1.0 1201207 TimTec1_007558 Cc1ccc(cc1C)c2csc(n2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H13 compound treatment 0.536 0.284 15.27 15.2683 1.0 1304451 TimTec1_007559 CCC(=O)Nc1cccc(NC(=O)c2cc3ccccc3o2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H14 compound treatment 0.503 0.251 13.49 13.4949 1.0 3211656 TimTec1_007560 CCOc1ccc2[nH]c(=O)c(Cc3ccccc3)c(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H15 compound treatment 0.248 -0.00388 -0.21 -0.2082 -1.0 3211657 TimTec1_007561 CC(Sc1ccc(C)cc1)C(=O)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H16 compound treatment 0.549 0.297 15.97 15.9669 1.0 3087394 TimTec1_007562 Clc1cccc(c1)c2nc(no2)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H17 compound treatment 0.389 0.137 7.37 7.3688 1.0 3211658 TimTec1_007563 CCC(=O)N1CCN(CC1)c2ccc(NCc3ccccc3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H18 compound treatment 0.253 0.00112 0.06 0.0605 1.0 1531690 TimTec1_007564 O=C1NCCCc2nc(Oc3ccccc3)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H19 compound treatment 0.492 0.24 12.9 12.9038 1.0 3211659 TimTec1_007565 O=C(NCCc1ccccc1)c2cnc3ccccn3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H20 compound treatment 0.452 0.2 10.75 10.7543 1.0 3087395 TimTec1_007566 CC(=O)Nc1ccc(Oc2ccc(cc2)c3noc(C)n3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H21 compound treatment 0.353 0.101 5.43 5.4342 1.0 3211660 TimTec1_007567 CC1=CC(C)(C)N(C(=O)CSc2ccccn2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H22 compound treatment 0.273 0.0211 1.14 1.1352 1.0 1143596 TimTec1_007568 Cc1cc(NCc2cccnc2)c3ccc(Cl)cc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H23 mock treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 H24 mock treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I01 compound treatment 0.568 0.316 16.99 16.9879 1.0 3211661 TimTec1_007569 Cc1[nH]c2ccccc2c1C(=O)CSc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I02 compound treatment 0.256 0.00412 0.22 0.2217 1.0 3087396 TimTec1_007570 CCCC(=O)Nc1nnc(s1)c2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I03 compound treatment 0.233 -0.0189 -1.01 -1.0143 -1.0 3211662 TimTec1_007571 Fc1ccc(NC(=O)C2CC(=O)N3CCN=C3S2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I04 compound treatment 0.258 0.00612 0.33 0.3291 1.0 1690088 TimTec1_007572 Cc1nc(=O)c(c(C)n1Cc2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I05 compound treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 3087397 TimTec1_007573 Cc1cc2nc3CCCCc3c(n2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I06 compound treatment 0.251 -8.75E-4 -0.05 -0.047 -1.0 3211663 TimTec1_007574 O=C(Nc1ncnc2sc3CCCc3c12)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I07 compound treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 3087398 TimTec1_007575 COc1ccc(cc1)C2(CCOCC2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I08 compound treatment 0.507 0.255 13.71 13.7099 1.0 1232670 TimTec1_007576 CC(=O)Nc1ccc(cc1)c2nc3ccc(NC(=O)C)cc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I09 compound treatment 0.239 -0.0129 -0.69 -0.6919 -1.0 3087399 TimTec1_007577 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccccc4C(F)(F)F)C(=O)CC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I10 compound treatment 0.249 -0.00288 -0.15 -0.1545 -1.0 3211664 TimTec1_007578 CC(C)(C)c1oc(cc1CN2CCCC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I11 compound treatment 0.275 0.0231 1.24 1.2427 1.0 3087400 TimTec1_007579 FC(F)(F)c1ccc(Cl)c(c1)c2ccc(C#N)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I12 compound treatment 0.401 0.149 8.01 8.0137 1.0 3211665 TimTec1_007580 Cc1ccc(cc1)c2nc(C#N)c(NCc3ccc4OCOc4c3)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I13 compound treatment 0.275 0.0231 1.24 1.2427 1.0 1228965 TimTec1_007581 CCC(Oc1ccccc1)C(=O)Nc2nncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I14 compound treatment 0.515 0.263 14.14 14.1398 1.0 3211666 TimTec1_007582 Clc1c(sc2cc(Cl)ccc12)C(=O)NCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I15 compound treatment 0.403 0.151 8.12 8.1211 1.0 1872119 TimTec1_007583 O=C(COC(=O)c1cnccn1)c2ccc(cc2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I16 compound treatment 0.273 0.0211 1.14 1.1352 1.0 3087401 TimTec1_007584 COc1cccc(CN2C(=O)C3(C(=C(N)OC4=C3C(=O)CCC4)C#N)c5ccccc25)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I17 compound treatment 0.287 0.0351 1.89 1.8875 1.0 3211667 TimTec1_007585 CCc1cccc2c(C#N)cn(CC(=O)NCc3ccco3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I18 compound treatment 0.604 0.352 18.92 18.9225 1.0 3211668 TimTec1_007586 Nc1c(Nc2ccc(F)cc2)sc3c(O)cc(=O)[nH]c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I19 compound treatment 0.334 0.0821 4.41 4.4132 1.0 3087402 TimTec1_007587 COc1cc2[nH]c(=O)c(C(=O)NC(C)c3ccccc3)c(O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I20 compound treatment 0.373 0.121 6.51 6.509 1.0 3211669 TimTec1_007588 CN(C(=O)Cn1cc(C#N)c2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I21 compound treatment 0.511 0.259 13.92 13.9248 1.0 3211670 TimTec1_007589 O=C(Nc1ccc2oc(=O)ccc2c1)c3cc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I22 compound treatment 0.414 0.162 8.71 8.7123 1.0 3087403 TimTec1_007590 Cc1nnc2SC(=CC=Nn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I23 mock treatment 0.251 -8.75E-4 -0.05 -0.047 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 I24 mock treatment 0.259 0.00712 0.38 0.3829 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J01 compound treatment 0.491 0.239 12.85 12.8501 1.0 3087404 TimTec1_007591 COc1ccc(OCCn2cc(C#N)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J02 compound treatment 0.277 0.0251 1.35 1.3502 1.0 3211671 TimTec1_007592 Cc1ccc(NC(=O)C2C3CC(C)(Oc4ccccc34)N(CCO)C2=O)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J03 compound treatment 0.491 0.239 12.85 12.8501 1.0 3211672 TimTec1_007593 CC(=O)Nc1cccc(c1)c2csc(Nc3cccc(O)c3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J04 compound treatment 0.253 0.00112 0.06 0.0605 1.0 3087405 TimTec1_007594 CCOC(=O)c1cc(CN2CCOCC2)oc1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J05 compound treatment 0.253 0.00112 0.06 0.0605 1.0 1516475 TimTec1_007595 O=C(CC1CCCCC1)Nc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J06 compound treatment 0.357 0.105 5.65 5.6492 1.0 3087406 TimTec1_007596 O=C(Cn/1ccs\c1=N\C(=O)c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J07 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 3211673 TimTec1_007597 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J08 compound treatment 0.264 0.0121 0.65 0.6516 1.0 1134872 TimTec1_007598 CC(C)n1c(NCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J09 compound treatment 0.247 -0.00488 -0.26 -0.262 -1.0 3211674 TimTec1_007599 O=C(NCCN1CCCCC1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J10 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 1510800 TimTec1_007600 Cc1cccc(NC(=O)c2cc(O)nc3ccccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J11 compound treatment 0.385 0.133 7.15 7.1539 1.0 3087407 TimTec1_007601 COc1ccc(OCC(=O)Nc2ncccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J12 compound treatment 0.261 0.00912 0.49 0.4904 1.0 3211675 TimTec1_007602 O=C(CSc1nc(nc2CCCCc12)c3ccccc3)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J13 compound treatment 0.366 0.114 6.13 6.1328 1.0 3087408 TimTec1_007603 NS(=O)(=O)c1csc(c1)C(=O)Nc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J14 compound treatment 0.529 0.277 14.89 14.8921 1.0 3211676 TimTec1_007604 Cc1ccc(cc1C)C(=O)CCc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J15 compound treatment 0.249 -0.00288 -0.15 -0.1545 -1.0 1344730 TimTec1_007605 NC(=O)c1ccc(CN2CCc3ccccc3C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J16 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3211677 TimTec1_007606 CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc2nnc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J17 compound treatment 0.293 0.0411 2.21 2.21 1.0 3211775 TimTec1_007607 O=C(NCCSC1CCCCC1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J18 compound treatment 0.477 0.225 12.1 12.0977 1.0 3087409 TimTec1_007608 OC(=O)CCCC(=O)Nc1ccc(cc1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J19 compound treatment 0.273 0.0211 1.14 1.1352 1.0 3211776 TimTec1_007609 Clc1ccc(CNC(=O)Cc2cccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J20 compound treatment 0.411 0.159 8.55 8.551 1.0 3211777 TimTec1_007610 CCC(=O)Nc1cc(ccc1C)C(=O)OCC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J21 compound treatment 0.247 -0.00488 -0.26 -0.262 -1.0 3087410 TimTec1_007611 CN1CCN(CC1)c2nc(=O)c3CCCCc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J22 compound treatment 0.293 0.0411 2.21 2.21 1.0 1397831 TimTec1_007612 C1Cc2nc3ccccc3c(N4CCOCC4)c2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J23 mock treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 J24 mock treatment 0.245 -0.00688 -0.37 -0.3694 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K01 compound treatment 0.234 -0.0179 -0.96 -0.9606 -1.0 3211778 TimTec1_007613 CC1(C)CC(=O)C2=C(C1)Nc3nn(c(O)c3C2c4ccco4)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K02 compound treatment 0.283 0.0311 1.67 1.6726 1.0 1406475 TimTec1_007614 Nc1nc2ccccc2n1Cc3ccc(Cl)c(Cl)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K03 compound treatment 0.531 0.279 15.0 14.9996 1.0 3087411 TimTec1_007615 Oc1ccccc1CNc2cnc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K04 compound treatment 0.333 0.0811 4.36 4.3595 1.0 1715858 TimTec1_007616 COc1ccc(Nc2nnc(C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K05 compound treatment 0.29 0.0381 2.05 2.0488 1.0 3087412 TimTec1_007617 CCOC(=O)c1cnc2cc(C)nn2c1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K06 compound treatment 0.301 0.0491 2.64 2.6399 1.0 3211779 TimTec1_007618 CC(OC(=O)CCc1c[nH]c2ccccc12)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K07 compound treatment 0.471 0.219 11.78 11.7753 1.0 3211780 TimTec1_007619 Cc1cc(SCCOc2ccc(Cl)cc2Cl)nc(N)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K08 compound treatment 0.313 0.0611 3.28 3.2847 1.0 1285395 TimTec1_007620 COc1cccc2cc(C(=O)N3CCN(CCO)CC3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K09 compound treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 1875159 TimTec1_007621 CC(Oc1ccc(F)cc1)C(=O)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K10 compound treatment 0.389 0.137 7.37 7.3688 1.0 3086523 TimTec1_007622 COC(=O)C(Cc1ccccc1)NC(=O)c2cc(oc2C)c3ccc4OCCOc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K11 compound treatment 0.386 0.134 7.21 7.2076 1.0 3086524 TimTec1_007623 CCc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K12 compound treatment 0.315 0.0631 3.39 3.3922 1.0 3086525 TimTec1_007624 Cc1nc(C#N)c(NCc2ccc(C)cc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K13 compound treatment 0.256 0.00412 0.22 0.2217 1.0 3086526 TimTec1_007625 O=C(Cc1cccc2ccccc12)NCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K14 compound treatment 0.256 0.00412 0.22 0.2217 1.0 3086527 TimTec1_007626 O=C(NCCNC1CCCCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K15 compound treatment 0.45 0.198 10.65 10.6468 1.0 3211781 TimTec1_007627 Cc1cc(C(=O)OCC(=O)N(c2ccccc2)c3ccccc3)c4ccccc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K16 compound treatment 0.411 0.159 8.55 8.551 1.0 3086528 TimTec1_007628 CC(C)OC(=O)C1=C(N)Oc2cc(C)oc(=O)c2C1c3ccc(cc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K17 compound treatment 0.287 0.0351 1.89 1.8875 1.0 3211782 TimTec1_007629 COc1ccc(cc1)C(=O)NCc2ccoc2C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K18 compound treatment 0.407 0.155 8.34 8.3361 1.0 3086529 TimTec1_007630 CC(C)N1C(=O)C(O)(CC(=O)c2ccccc2O)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K19 compound treatment 0.351 0.0991 5.33 5.3268 1.0 1862563 TimTec1_007631 O=C(COc1cccc2ccccc12)Nc3ccc(CN4CCOCC4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K20 compound treatment 0.258 0.00612 0.33 0.3291 1.0 3211783 TimTec1_007632 CCOc1cc(CNn2cnnc2)cc(Cl)c1OCC(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K21 compound treatment 0.308 0.0561 3.02 3.016 1.0 3086530 TimTec1_007633 NCc1ccc(cc1)c2nc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K22 compound treatment 0.277 0.0251 1.35 1.3502 1.0 3086531 TimTec1_007634 Cc1nn2c3cc(ccc3nc2c4ccccc14)N5CCOCC5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K23 mock treatment 0.261 0.00912 0.49 0.4904 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 K24 mock treatment 0.253 0.00112 0.06 0.0605 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L01 compound treatment 0.383 0.131 7.05 7.0464 1.0 3211784 TimTec1_007635 Fc1ccc(Cn2cc(C#N)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L02 compound treatment 0.462 0.21 11.29 11.2917 1.0 3211785 TimTec1_007636 CC1(C)CNC(=O)c2sc(NC(=O)c3ccccc3Cl)nc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L03 compound treatment 0.255 0.00312 0.17 0.1679 1.0 3086532 TimTec1_007637 Cc1ccc2[nH]c(CCC(=O)O)nc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L04 compound treatment 0.271 0.0191 1.03 1.0277 1.0 1861878 TimTec1_007638 O=C(Nc1ccccc1N2CCCC2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L05 compound treatment 0.456 0.204 10.97 10.9693 1.0 1581232 TimTec1_007639 CCc1ccc(OCC(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L06 compound treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 3211786 TimTec1_007640 O=C1CCCC2=C1C(C3=C(CCCC3=O)N2)c4cccc5ccccc45 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L07 compound treatment 0.251 -8.75E-4 -0.05 -0.047 -1.0 3086533 TimTec1_007641 O=C(NCCN1CCOCC1)c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L08 compound treatment 0.305 0.0531 2.85 2.8548 1.0 1650547 TimTec1_007642 Oc1ccc(COCc2ccccc2)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L09 compound treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 3086534 TimTec1_007643 CC(CN1CCCC1)OC(=O)c2ccccc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L10 compound treatment 0.427 0.175 9.41 9.4109 1.0 1613918 TimTec1_007644 OC(=O)c1c(NC(=O)c2cccs2)scc1c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L11 compound treatment 0.258 0.00612 0.33 0.3291 1.0 3211787 TimTec1_007645 O=C(NCCN1CCOCC1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L12 compound treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 3086535 TimTec1_007646 CN(CC(=O)NC1CCCCC1)S(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L13 compound treatment 0.338 0.0861 4.63 4.6282 1.0 1502643 TimTec1_007647 CCOc1ccc(NCC(=O)Nc2ccc(F)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L14 compound treatment 0.32 0.0681 3.66 3.6609 1.0 3211788 TimTec1_007648 CCOc1ccc(cc1)C(=O)CCc2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L15 compound treatment 0.27 0.0181 0.97 0.974 1.0 3086536 TimTec1_007649 Cc1ccc(cc1n2cccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L16 compound treatment 0.287 0.0351 1.89 1.8875 1.0 1742683 TimTec1_007650 CC(Oc1cccc(Cl)c1)C(=O)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L17 compound treatment 0.334 0.0821 4.41 4.4132 1.0 3211789 TimTec1_007651 O=C(NCCSc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L18 compound treatment 0.474 0.222 11.94 11.9365 1.0 3211790 TimTec1_007652 O=C(Cc1cccs1)Nc2cccc(c2)C(=O)Nc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L19 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 1196911 TimTec1_007653 Cc1onc(c1C(=O)NC2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L20 compound treatment 0.344 0.0921 4.95 4.9506 1.0 1436556 TimTec1_007654 Cc1ccc(cc1C)C(=O)COC(=O)c2cnccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L21 compound treatment 0.276 0.0241 1.3 1.2964 1.0 3086537 TimTec1_007655 CC1=C(Sc2ccccc2N1)C(=O)Nc3ccccc3C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L22 compound treatment 0.313 0.0611 3.28 3.2847 1.0 3211791 TimTec1_007656 CC(C)C(=O)Nc1nc(cs1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L23 mock treatment 0.256 0.00412 0.22 0.2217 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 L24 mock treatment 0.252 1.25E-4 0.01 0.0067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M01 compound treatment 0.28 0.0281 1.51 1.5114 1.0 3211792 TimTec1_007657 COc1ccccc1NC(=O)C2=C(C)Nc3ccccc3S2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M02 compound treatment 0.331 0.0791 4.25 4.252 1.0 3086538 TimTec1_007658 COCc1nc2ccccc2n1Cc3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M03 compound treatment 0.239 -0.0129 -0.69 -0.6919 -1.0 3211793 TimTec1_007659 CCOC(=O)C1C2OC3(CN(C4CCCC4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M04 compound treatment 0.448 0.196 10.54 10.5393 1.0 1193736 TimTec1_007660 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M05 compound treatment 0.455 0.203 10.92 10.9155 1.0 1412527 TimTec1_007661 Cc1cc(C)cc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)NCC=C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M06 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 3211794 TimTec1_007662 CCOc1ccccc1C(=O)N(Cc2cc3ccccc3nc2O)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M07 compound treatment 0.269 0.0171 0.92 0.9203 1.0 3086539 TimTec1_007663 O=C(Nc1cccc2ccccc12)C3CC(=O)OC43CCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M08 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3086540 TimTec1_007664 Clc1snc(C(=O)CC#N)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M09 compound treatment 0.468 0.216 11.61 11.6141 1.0 3211795 TimTec1_007665 O=C(C1CC1)c2cn(CCOc3ccccc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M10 compound treatment 0.239 -0.0129 -0.69 -0.6919 -1.0 1574331 TimTec1_007666 COC(=O)CC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M11 compound treatment 0.345 0.0931 5.0 5.0043 1.0 3086541 TimTec1_007667 O=c1oc2ccccc2n1CCOc3cccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M12 compound treatment 0.261 0.00912 0.49 0.4904 1.0 1870621 TimTec1_007668 COC(=O)C1=C(C)NC(=O)NC1/C=C/c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M13 compound treatment 0.441 0.189 10.16 10.1632 1.0 3086542 TimTec1_007669 O=C(Cc1cccc2ccccc12)Nc3ccc(CCC(=O)N4CCCC4)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M14 compound treatment 0.386 0.134 7.21 7.2076 1.0 3211878 TimTec1_007670 FC(F)(F)c1ccc(Cn2cnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M15 compound treatment 0.277 0.0251 1.35 1.3502 1.0 1522627 TimTec1_007671 CC(C)(C)C1CCc2c(C(=O)N)c(N)sc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M16 compound treatment 0.264 0.0121 0.65 0.6516 1.0 3086543 TimTec1_007672 Cc1cc(CO)c(C)n1c2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M17 compound treatment 0.423 0.171 9.2 9.1959 1.0 3211879 TimTec1_007673 COC(=O)c1cn(Cc2ccc(C#N)cc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M18 compound treatment 0.266 0.0141 0.76 0.759 1.0 1572395 TimTec1_007674 NC(=O)C1CCN(CC1)C(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M19 compound treatment 0.386 0.134 7.21 7.2076 1.0 3211880 TimTec1_007675 CN1CCN(CC1)c2ccc(NC(=O)COc3cccc4ccccc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M20 compound treatment 0.576 0.324 17.42 17.4178 1.0 3086544 TimTec1_007676 O=C(COc1cccc(NC(=O)c2ccco2)c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M21 compound treatment 0.285 0.0331 1.78 1.7801 1.0 3211881 TimTec1_007677 COC(=O)Cn1cc(C(=O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M22 compound treatment 0.539 0.287 15.43 15.4295 1.0 1168606 TimTec1_007678 Oc1ccc(cc1)c2nc(cs2)c3c[nH]c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M23 mock treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 M24 mock treatment 0.259 0.00712 0.38 0.3829 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N01 compound treatment 0.275 0.0231 1.24 1.2427 1.0 3211882 TimTec1_007679 O=C(Cn1cc(C#N)c2ccccc12)N3CCc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N02 compound treatment 0.258 0.00612 0.33 0.3291 1.0 3086545 TimTec1_007680 Fc1ccc(cc1F)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N03 compound treatment 0.581 0.329 17.69 17.6865 1.0 3211883 TimTec1_007681 CC1(C)CC(=O)c2sc(NC(=O)CCCc3ccccc3)nc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N04 compound treatment 0.318 0.0661 3.55 3.5534 1.0 3086546 TimTec1_007682 CC(=O)Nc1ccc(cc1)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N05 compound treatment 0.489 0.237 12.74 12.7426 1.0 1245976 TimTec1_007683 CC(C)c1ccc(OCC(=O)N2CCC(CC2)C(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N06 compound treatment 0.269 0.0171 0.92 0.9203 1.0 3211884 TimTec1_007684 CCCOc1ccc(NC(=O)C2CN(C(C)C)C(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N07 compound treatment 0.237 -0.0149 -0.8 -0.7994 -1.0 3086547 TimTec1_007685 Cc1cc(C)cc(c1)C(=O)Nc2nnc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N08 compound treatment 0.292 0.0401 2.16 2.1562 1.0 3211885 TimTec1_007686 COc1ccccc1OCC(=O)Nc2sc3CCCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N09 compound treatment 0.247 -0.00488 -0.26 -0.262 -1.0 3086548 TimTec1_007687 CC(CN1CCCC1)OC(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N10 compound treatment 0.509 0.257 13.82 13.8174 1.0 1285500 TimTec1_007688 OCCNC(=O)c1cc2sc3ccccc3c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N11 compound treatment 0.607 0.355 19.08 19.0837 1.0 3086549 TimTec1_007689 Cc1ccc(cc1C)C2OC3C=CC(=CC3=N2)NC(=O)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N12 compound treatment 0.246 -0.00588 -0.32 -0.3157 -1.0 3211886 TimTec1_007690 Cc1ccc(C)n1c2oc(C)c(C)c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N13 compound treatment 0.462 0.21 11.29 11.2917 1.0 3211887 TimTec1_007691 Cc1cc(O)n2nc(NC(=O)c3cccs3)nc2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N14 compound treatment 0.32 0.0681 3.66 3.6609 1.0 3086550 TimTec1_007692 Clc1ccccc1OCC(=O)N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N15 compound treatment 0.262 0.0101 0.54 0.5441 1.0 3211888 TimTec1_007693 Cc1cccc(NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N16 compound treatment 0.327 0.0751 4.04 4.0371 1.0 3086551 TimTec1_007694 OCc1cn(nc1c2cccnc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N17 compound treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 1673666 TimTec1_007695 COc1ccc(CNC(Cc2ccccc2)c3ccccc3)c(OC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N18 compound treatment 0.267 0.0151 0.81 0.8128 1.0 3086552 TimTec1_007696 Clc1ccc(CSCC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N19 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3211889 TimTec1_007697 Cc1onc(c1C(=O)Nc2cccnc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N20 compound treatment 0.305 0.0531 2.85 2.8548 1.0 3211890 TimTec1_007698 CC(=O)Nc1ccc(Oc2cc(C#N)c(C#N)cc2N3CCOCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N21 compound treatment 0.332 0.0801 4.31 4.3057 1.0 3086553 TimTec1_007699 O=C(NC1=NC(=O)CC2N1CCNC2=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N22 compound treatment 0.307 0.0551 2.96 2.9623 1.0 1456550 TimTec1_007700 O=C(Cn1cnc2ccccc2c1=O)OC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N23 mock treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 N24 mock treatment 0.245 -0.00688 -0.37 -0.3694 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O01 compound treatment 0.239 -0.0129 -0.69 -0.6919 -1.0 3211891 TimTec1_007701 CCOc1ccc(NC2=NC(CC(=O)N2)C(=O)NCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O02 compound treatment 0.257 0.00512 0.28 0.2754 1.0 1687553 TimTec1_007702 Cc1ccc(cc1)C(=O)Cn2c3ncnn3c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O03 compound treatment 0.255 0.00312 0.17 0.1679 1.0 3211892 TimTec1_007703 CCOC(=O)Cc1[nH]nc2OC(=C(C#N)C(c12)c3ccc(Cl)cc3)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O04 compound treatment 0.315 0.0631 3.39 3.3922 1.0 3086792 TimTec1_007704 COc1cccc(CNc2nc3ccccc3n2CCN4CCOCC4)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O05 compound treatment 0.26 0.00812 0.44 0.4366 1.0 3086793 TimTec1_007705 COc1ccc(cc1)c2ccc(CCC(=O)O)n2C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O06 compound treatment 0.27 0.0181 0.97 0.974 1.0 3086794 TimTec1_007706 COc1ccc2nc(O)c(CN(C(=O)C)c3cccc(C)c3)cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O07 compound treatment 0.259 0.00712 0.38 0.3829 1.0 3086795 TimTec1_007707 COc1ccc(Cl)cc1n2cnc3sc(C)c(C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O08 compound treatment 0.241 -0.0109 -0.58 -0.5844 -1.0 3086796 TimTec1_007708 CN(C)C(=O)c1ccccc1NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O09 compound treatment 0.258 0.00612 0.33 0.3291 1.0 3086797 TimTec1_007709 CC(C)(C)OC(=O)CN1C(=O)c2ccccc2S1(=O)=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O10 compound treatment 0.271 0.0191 1.03 1.0277 1.0 3086798 TimTec1_007710 Cc1ccc(N2CCN(CC2)C(=O)c3cccs3)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O11 compound treatment 0.507 0.255 13.71 13.7099 1.0 3211893 TimTec1_007711 O=c1oc2ccccc2n1CCCOc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O12 compound treatment 0.356 0.104 5.6 5.5955 1.0 1875235 TimTec1_007712 CCn1c(=N)c(C#N)cc2c(=O)n3ccccc3nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O13 compound treatment 0.298 0.0461 2.48 2.4787 1.0 1241828 TimTec1_007713 CCC(=O)Nc1sc2CCCc2c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O14 compound treatment 0.278 0.0261 1.4 1.4039 1.0 3211894 TimTec1_007714 FC(F)(F)c1ccccc1CNCCc2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O15 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 3211895 TimTec1_007715 CCn1nnc(NC(=O)Cc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O16 compound treatment 0.503 0.251 13.49 13.4949 1.0 3086799 TimTec1_007716 CC(=O)N1CCN(CC1)c2ccc(NC(=O)COc3ccc4ccccc4c3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O17 compound treatment 0.459 0.207 11.13 11.1305 1.0 3211896 TimTec1_007717 Cc1ccc2nc(O)cc(C(=O)OCC(=O)c3ccc(F)cc3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O18 compound treatment 0.282 0.0301 1.62 1.6189 1.0 3211897 TimTec1_007718 Nc1nonc1c2nc3ccccc3n2CC(=O)Nc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O19 compound treatment 0.25 -0.00188 -0.1 -0.1008 -1.0 3086800 TimTec1_007719 CC(=O)Nc1c(C)nc2ncnn2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O20 compound treatment 0.281 0.0291 1.57 1.5651 1.0 3211898 TimTec1_007720 Cc1ccc2nc(C)cc(C(=O)OCC(=O)C(C)(C)C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O21 compound treatment 0.417 0.165 8.87 8.8735 1.0 1528103 TimTec1_007721 Clc1ccc(Cl)c(NC(=O)C2COc3ccccc3O2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O22 compound treatment 0.522 0.27 14.52 14.516 1.0 3211899 TimTec1_007722 N(c1nc(cs1)c2cccs2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O23 mock treatment 0.266 0.0141 0.76 0.759 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 O24 mock treatment 0.251 -8.75E-4 -0.05 -0.047 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P01 compound treatment 0.265 0.0131 0.71 0.7053 1.0 1787717 TimTec1_007723 CCN(CC)C(=O)Cn1cc(C#N)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P02 compound treatment 0.26 0.00812 0.44 0.4366 1.0 1448248 TimTec1_007724 CC(Oc1ccccc1)C(=O)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P03 compound treatment 0.272 0.0201 1.08 1.0815 1.0 1288426 TimTec1_007725 CC(=O)Nc1ccccc1NC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P04 compound treatment 0.465 0.213 11.45 11.4529 1.0 3211900 TimTec1_007726 COc1ccc(NC(=O)COC(=O)C2CN(Cc3ccc(C)cc3)C(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P05 compound treatment 0.462 0.21 11.29 11.2917 1.0 3211901 TimTec1_007727 Clc1ccc(OCCCC(=O)NCc2ccncc2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P06 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3086801 TimTec1_007728 CC(=O)Nc1ccc(NC(=O)C2CN(Cc3ccccc3)C(=O)C2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P07 compound treatment 0.254 0.00212 0.11 0.1142 1.0 3211960 TimTec1_007729 Cc1ccc(OCC(=O)n2cnnc2N)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P08 compound treatment 0.302 0.0501 2.69 2.6936 1.0 1516476 TimTec1_007730 CC(C)(C)Nc1ncnc2n(Cc3ccccc3)ncc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P09 compound treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 3086802 TimTec1_007731 COc1ccccc1C(=O)OC2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P10 compound treatment 0.32 0.0681 3.66 3.6609 1.0 3086803 TimTec1_007732 Cc1sc2nc(oc(=O)c2c1C)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P11 compound treatment 0.337 0.0851 4.57 4.5744 1.0 1413821 TimTec1_007733 CCCC(=O)Nc1cccc(NC(=O)c2cccnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P12 compound treatment 0.244 -0.00788 -0.42 -0.4232 -1.0 3086804 TimTec1_007734 FC(F)(F)c1nn(CC(=O)N2CCCC2)c3CCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P13 compound treatment 0.248 -0.00388 -0.21 -0.2082 -1.0 1351196 TimTec1_007735 COc1ccccc1NC(=O)CC2N(C(=O)c3ccccc3)c4ccccc4NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P14 compound treatment 0.491 0.239 12.85 12.8501 1.0 3086805 TimTec1_007736 Cc1cccc(Nc2nc(cs2)c3ccc(F)cc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P15 compound treatment 0.369 0.117 6.29 6.2941 1.0 3211961 TimTec1_007737 O=C(C1CC1)c2cn(Cc3ccccc3)c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P16 compound treatment 0.335 0.0831 4.47 4.467 1.0 3086806 TimTec1_007738 Cc1ccc(cc1)c2nn(CCC#N)cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P17 compound treatment 0.243 -0.00888 -0.48 -0.4769 -1.0 3211962 TimTec1_007739 COc1cc(OC)c(cc1OC)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P18 compound treatment 0.242 -0.00988 -0.53 -0.5307 -1.0 1878712 TimTec1_007740 CC1=C(C)CC(C(C1)C(=O)O)C(=O)N2CCN(Cc3ccccc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P19 compound treatment 0.322 0.0701 3.77 3.7684 1.0 1288850 TimTec1_007741 O=C(Nc1ccc2OCOc2c1)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P20 compound treatment 0.309 0.0571 3.07 3.0698 1.0 3211963 TimTec1_007742 Clc1ccc(NC(=O)NCC2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P21 compound treatment 0.252 1.25E-4 0.01 0.0067 1.0 3086807 TimTec1_007743 CCCc1nc(Nc2nc3ccccc3o2)ncc1C(=O)OCC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P22 compound treatment 0.314 0.0621 3.34 3.3385 1.0 1454174 TimTec1_007744 O=C(Cn1cnc2ccccc2c1=O)OCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P23 mock treatment 0.253 0.00112 0.06 0.0605 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2084 P24 mock treatment 0.255 0.00312 0.17 0.1679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A01 compound treatment 0.487 0.238 12.76 12.7644 1.0 3086808 TimTec1_007745 CCC(=O)c1cc(c2nc3ccccc3n2C)n(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A02 compound treatment 0.298 0.0485 2.61 2.608 1.0 3211964 TimTec1_007746 COC(=O)C1=C(C)OC(=C(C#N)C21C(=O)N(C)c3ccccc32)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A03 compound treatment 0.198 -0.0515 -2.77 -2.7658 -1.0 3211965 TimTec1_007747 OC(=O)C1C2OC3(CN(C(=O)C13)c4ccc(Cl)c(F)c4)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A04 compound treatment 0.229 -0.0205 -1.1 -1.0999 -1.0 3086809 TimTec1_007748 CN1CCN(CC1)c2nc(NCC3CCCO3)c4ccccc4n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A05 compound treatment 0.457 0.208 11.15 11.1523 1.0 3211966 TimTec1_007749 Cc1ccccc1c2nc3cc(NC(=O)C4CC4)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A06 compound treatment 0.56 0.311 16.69 16.6873 1.0 3086810 TimTec1_007750 Oc1nc2ccccc2cc1c3noc(n3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A07 compound treatment 0.433 0.184 9.86 9.8626 1.0 1670347 TimTec1_007751 CCOC(=O)c1cnc2c(Cl)cccc2c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A08 compound treatment 0.509 0.26 13.95 13.9467 1.0 3211967 TimTec1_007752 Clc1ccccc1c2ccc(o2)C(=O)NCc3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A09 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 1861788 TimTec1_007753 O=C(COc1ccccc1)Nc2ccccc2N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A10 compound treatment 0.259 0.00953 0.51 0.5122 1.0 1428766 TimTec1_007754 COc1ccc2oc(=O)c(cc2c1)C(=O)N(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A11 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 3086811 TimTec1_007755 CCN(CC)C(=O)Cn1cc(C(=O)CC)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A12 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3211968 TimTec1_007756 Cc1cc(C)n(n1)c2nc3ccccc3[nH]c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A13 compound treatment 0.406 0.157 8.41 8.4117 1.0 3086812 TimTec1_007757 CCCC(=O)Nc1ccc2C(=O)OCc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A14 compound treatment 0.234 -0.0155 -0.83 -0.8313 -1.0 1600399 TimTec1_007758 CC1CN(C)CC(C)C1(O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A15 compound treatment 0.295 0.0455 2.45 2.4468 1.0 1787715 TimTec1_007759 O=C(Cn1cc(C#N)c2ccccc12)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A16 compound treatment 0.321 0.0715 3.84 3.8439 1.0 3086813 TimTec1_007760 COc1ccccc1NC(CC(=O)c2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A17 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3211969 TimTec1_007761 CCc1cc2c(ncnc2s1)N3CCN(CC3)c4nc(C)cc(C)n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A18 compound treatment 0.261 0.0115 0.62 0.6197 1.0 1862419 TimTec1_007762 O=C(Cc1ccccc1)Nc2ccccc2N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A19 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1358875 TimTec1_007763 CC1(C)C2(C)CCC1(CC2=O)C(=O)NC3CC(C)(C)NC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A20 compound treatment 0.272 0.0225 1.21 1.2108 1.0 1449265 TimTec1_007764 Cc1ccc(NC(=O)COC(=O)c2cccs2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A21 compound treatment 0.327 0.0775 4.17 4.1664 1.0 3211970 TimTec1_007765 Cc1cc(NC(=O)Cc2cccc3ccccc23)no1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A22 compound treatment 0.471 0.222 11.9 11.9046 1.0 1377950 TimTec1_007766 Cc1cc(N)cc2nc([nH]c12)c3ccc(N)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A23 mock treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 A24 mock treatment 0.272 0.0225 1.21 1.2108 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B01 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 1095008 TimTec1_007767 Cn1c(nc2c(=O)n(C)c(=O)[nH]c12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B02 compound treatment 0.452 0.203 10.88 10.8836 1.0 3211971 TimTec1_007768 CC(C)(C)C(=O)COC(=O)c1cccc(NC(=O)c2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B03 compound treatment 0.431 0.182 9.76 9.7551 1.0 3086814 TimTec1_007769 O=C(Cc1cccs1)Nc2nnc(Cc3ccccc3)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B04 compound treatment 0.266 0.0165 0.89 0.8884 1.0 3211972 TimTec1_007770 Cc1cc(nn1CC(=O)NCc2cccs2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B05 compound treatment 0.383 0.134 7.18 7.1757 1.0 1280407 TimTec1_007771 Cc1ccccc1OCC(=O)Nc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B06 compound treatment 0.274 0.0245 1.32 1.3183 1.0 1150838 TimTec1_007772 CCc1cccc(C)c1NC(=O)COC(=O)C2CN(C(=O)C2)c3ccc(OC(C)C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B07 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3086815 TimTec1_007773 O=C(NCCN1CCCCC1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B08 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3211973 TimTec1_007774 CCCNC(=O)C1CCN(CC1)C(=O)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B09 compound treatment 0.321 0.0715 3.84 3.8439 1.0 1292787 TimTec1_007775 O=C(COc1ccccc1)N2CCN(Cc3ccccn3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B10 compound treatment 0.381 0.132 7.07 7.0682 1.0 1281347 TimTec1_007776 COC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B11 compound treatment 0.274 0.0245 1.32 1.3183 1.0 3086816 TimTec1_007777 O=C(NCCC1=CCCCC1)c2cnsn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B12 compound treatment 0.417 0.168 9.0 9.0028 1.0 1285189 TimTec1_007778 CCOC(=O)c1nc2sc3CC(C)CCc3c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B13 compound treatment 0.329 0.0795 4.27 4.2738 1.0 3211974 TimTec1_007779 Clc1ccc(CNc2ccc3OCCOc3c2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B14 compound treatment 0.291 0.0415 2.23 2.2318 1.0 1677544 TimTec1_007780 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCc4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B15 compound treatment 0.31 0.0605 3.25 3.2528 1.0 3211975 TimTec1_007781 CCCOC(=O)Cn1cnc2sc(C)c(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B16 compound treatment 0.283 0.0335 1.8 1.8019 1.0 3211976 TimTec1_007782 CCC(Oc1ccccc1)C(=O)NCc2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B17 compound treatment 0.47 0.221 11.85 11.8509 1.0 3086817 TimTec1_007783 COC(=O)c1cc(on1)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B18 compound treatment 0.324 0.0745 4.01 4.0052 1.0 1678690 TimTec1_007784 COc1ccc(cc1)c2csc3ncn(CC=C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B19 compound treatment 0.268 0.0185 1.0 0.9958 1.0 1600545 TimTec1_007785 COc1ccc(OCC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B20 compound treatment 0.334 0.0845 4.54 4.5425 1.0 1255438 TimTec1_007786 Clc1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B21 compound treatment 0.272 0.0225 1.21 1.2108 1.0 3086818 TimTec1_007787 CCN1C=C(C(C(=C1)C(=O)OC)c2ccc(Cl)cc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B22 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3086862 TimTec1_007788 CCc1cccc(CC)c1NC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B23 mock treatment 0.25 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 B24 mock treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C01 compound treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 1318228 TimTec1_007789 Cc1cc(C)c(NC(=O)c2ccncc2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C02 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 3086863 TimTec1_007790 Clc1ccc(c2csc(Nc3ncccn3)n2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C03 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3086864 TimTec1_007791 CCCN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C04 compound treatment 0.301 0.0515 2.77 2.7692 1.0 3086865 TimTec1_007792 OCCNc1nc(nc2ccccc12)N3CCN(CC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C05 compound treatment 0.293 0.0435 2.34 2.3393 1.0 3086866 TimTec1_007793 CC(C)(C)NC(=O)c1cccc(NC(=O)Cc2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C06 compound treatment 0.455 0.206 11.04 11.0448 1.0 3086867 TimTec1_007794 OC1=C(C(N(Cc2ccccc2)C1=O)c3cccnc3)C(=O)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C07 compound treatment 0.274 0.0245 1.32 1.3183 1.0 1136666 TimTec1_007795 O=C1OCCC1Sc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C08 compound treatment 0.455 0.206 11.04 11.0448 1.0 3212034 TimTec1_007796 CC(C)C(=O)Nc1nnc(s1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C09 compound treatment 0.582 0.333 17.87 17.8695 1.0 3212035 TimTec1_007797 CCC(=O)N1CCN(CC1)c2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C10 compound treatment 0.311 0.0615 3.31 3.3066 1.0 3086868 TimTec1_007798 COc1ccc2oc(=O)c(cc2c1)C(=O)NC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C11 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3212036 TimTec1_007799 Cc1cc(C)c(C(=O)N)c(NCCc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C12 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 1098140 TimTec1_007800 O=S(=O)(N1CN2CCN(C2)C1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C13 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3212037 TimTec1_007801 Clc1ccccc1NC(=O)Cn2c(=O)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C14 compound treatment 0.252 0.00253 0.14 0.136 1.0 1203605 TimTec1_007802 CCC(=O)OC1(CC(C)N(C)CC1C)c2cccc(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C15 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3212038 TimTec1_007803 COC(=O)Cn1cc(C#N)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C16 compound treatment 0.44 0.191 10.24 10.2388 1.0 3086869 TimTec1_007804 CC(C)C(=O)Nc1ccc2nn(nc2c1)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C17 compound treatment 0.264 0.0145 0.78 0.7809 1.0 1546820 TimTec1_007805 O=C(N1CCN(CC1)C2CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C18 compound treatment 0.35 0.101 5.4 5.4023 1.0 1186833 TimTec1_007806 NC(=O)c1c(NC(=O)c2ccccc2)sc3CCCc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C19 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1584588 TimTec1_007807 CC1CCCN(C1)C(=O)C2(CCC3(C)C(=O)C2)C3(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C20 compound treatment 0.27 0.0205 1.1 1.1033 1.0 1147418 TimTec1_007808 Clc1cc(Cl)cc(NC(=O)COC(=O)C2CCCO2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C21 compound treatment 0.267 0.0175 0.94 0.9421 1.0 1448442 TimTec1_007809 COc1ccc(CNCC2COc3ccccc3O2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C22 compound treatment 0.331 0.0815 4.38 4.3813 1.0 1413356 TimTec1_007810 OC(=O)c1ccc(cc1O)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C23 mock treatment 0.262 0.0125 0.67 0.6734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 C24 mock treatment 0.25 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D01 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 1452042 TimTec1_007811 Clc1cccc(OCCN2CCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D02 compound treatment 0.332 0.0825 4.44 4.4351 1.0 3212039 TimTec1_007812 COc1ccc(cc1)N2CC(CC2=O)C(=O)OC(C)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D03 compound treatment 0.252 0.00253 0.14 0.136 1.0 3212040 TimTec1_007813 O=C(CS(=O)(=O)Cc1ccccc1)N2CCCc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D04 compound treatment 0.373 0.124 6.64 6.6383 1.0 1438278 TimTec1_007814 CN(C1CCCCC1)C(=O)c2cc3nc(cc(C)n3n2)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D05 compound treatment 0.312 0.0625 3.36 3.3603 1.0 3212041 TimTec1_007815 O=C(NCCC1=CCCCC1)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D06 compound treatment 0.257 0.00753 0.4 0.4047 1.0 3212042 TimTec1_007816 Cc1cccc(NC(=O)C2CN(C(=O)C2)c3ccccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D07 compound treatment 0.364 0.115 6.15 6.1547 1.0 3086870 TimTec1_007817 CC(=O)Nc1ccc(cc1)c2nc3ccccc3c(=O)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D08 compound treatment 0.528 0.279 14.97 14.9677 1.0 1679774 TimTec1_007818 O=C(Nc1ccc2oc(nc2c1)c3ccncc3)c4ccco4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D09 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3086871 TimTec1_007819 c1nnnn1c2ccccc2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D10 compound treatment 0.45 0.201 10.78 10.7761 1.0 1121757 TimTec1_007820 CC(C)OC(=O)C(C)n1cnc2sc(cc2c1=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D11 compound treatment 0.294 0.0445 2.39 2.393 1.0 3086872 TimTec1_007821 COC(=O)c1cccc(NC(=O)C2COc3ccccc3O2)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D12 compound treatment 0.296 0.0465 2.5 2.5005 1.0 3212043 TimTec1_007822 Clc1ccc(cc1)c2csc3ncn(CC=C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D13 compound treatment 0.301 0.0515 2.77 2.7692 1.0 3086873 TimTec1_007823 COc1cc(CNc2ccc3OCCOc3c2)ccc1OCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D14 compound treatment 0.274 0.0245 1.32 1.3183 1.0 1309609 TimTec1_007824 Cc1sc2ncn(CC(=O)Nc3ccccc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D15 compound treatment 0.405 0.156 8.36 8.3579 1.0 1697737 TimTec1_007825 O=c1n(CCc2ccccc2)cnc3sc4CCCCc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D16 compound treatment 0.264 0.0145 0.78 0.7809 1.0 1880627 TimTec1_007826 COc1ccc(NC(=O)C2CCCO2)c(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D17 compound treatment 0.272 0.0225 1.21 1.2108 1.0 3212044 TimTec1_007827 OC1=C(C(N(CCc2c[nH]c3ccccc23)C1=O)c4ccccn4)C(=O)c5ccccc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D18 compound treatment 0.292 0.0425 2.29 2.2855 1.0 3086874 TimTec1_007828 Cc1ccc(cc1C)c2csc3nc[nH]c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D19 compound treatment 0.337 0.0875 4.7 4.7037 1.0 1471052 TimTec1_007829 CC(C)(C)C(=O)Nc1ccc(NC(=O)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D20 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3086875 TimTec1_007830 Nc1c(c2nc3ccccc3s2)c4nc(C#N)c(C#N)nc4n1c5ccc(Cl)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D21 compound treatment 0.313 0.0635 3.41 3.414 1.0 3212045 TimTec1_007831 COC(=O)C1=CN(C=C(C1c2cccs2)C(=O)OC)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D22 compound treatment 0.284 0.0345 1.86 1.8556 1.0 3212046 TimTec1_007832 CCCNC(=O)c1ccccc1NC(=O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D23 mock treatment 0.252 0.00253 0.14 0.136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 D24 mock treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E01 compound treatment 0.418 0.169 9.06 9.0565 1.0 3086876 TimTec1_007833 O=C(CSc1nncc2ccccc12)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E02 compound treatment 0.565 0.316 16.96 16.956 1.0 3212047 TimTec1_007834 C(Cc1ccccc1)Nc2nc(cs2)c3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E03 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1261375 TimTec1_007835 CC1CCCCN1C(=O)c2c(C)onc2c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E04 compound treatment 0.311 0.0615 3.31 3.3066 1.0 3212048 TimTec1_007836 Cc1cc2c(=O)[nH]c(Cc3ccccc3)nc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E05 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3086877 TimTec1_007837 OC(=O)CCC(=O)N1CCNC(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E06 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3212049 TimTec1_007838 C(Cn1c(nc2ccccc12)N3CCCC3)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E07 compound treatment 0.492 0.243 13.03 13.0331 1.0 3212050 TimTec1_007839 COc1ccccc1NC(=O)CCSc2cccc3cccnc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E08 compound treatment 0.28 0.0305 1.64 1.6407 1.0 1217846 TimTec1_007840 COc1ccccc1C(CC(=O)O)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E09 compound treatment 0.264 0.0145 0.78 0.7809 1.0 3212051 TimTec1_007841 CC(Sc1ccc(C)cc1)C(=O)N2CCC(CC2)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E10 compound treatment 0.424 0.175 9.38 9.3789 1.0 1340156 TimTec1_007842 CC(OC(=O)c1cc(C)nc2ccccc12)C(=O)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E11 compound treatment 0.279 0.0295 1.59 1.5869 1.0 3212052 TimTec1_007843 CCOc1ccc(cc1)C2C3=C(CCCC3=O)N(CC)C4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E12 compound treatment 0.315 0.0655 3.52 3.5215 1.0 3086878 TimTec1_007844 CC(=O)N1CCn2c1nc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E13 compound treatment 0.256 0.00653 0.35 0.351 1.0 3212053 TimTec1_007845 Cc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E14 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1631753 TimTec1_007846 CC(C)N(C(=O)Cn1nnc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E15 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3212054 TimTec1_007847 CN(C)C(=O)C1=C(C)NC(=O)NC1c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E16 compound treatment 0.583 0.334 17.92 17.9233 1.0 3212055 TimTec1_007848 O=C(Nc1ccc2oc(nc2c1)c3cccnc3)c4cccs4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E17 compound treatment 0.31 0.0605 3.25 3.2528 1.0 1557418 TimTec1_007849 CN(CC(=O)O)S(=O)(=O)c1ccc2oc3ccccc3c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E18 compound treatment 0.279 0.0295 1.59 1.5869 1.0 3212115 TimTec1_007850 CC(c1ccccc1F)n2cc(nn2)C(=O)NCCCn3ccc(C)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E19 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3086879 TimTec1_007851 Cc1ccc(cc1)c2csc(CC(=O)N)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E20 compound treatment 0.46 0.211 11.31 11.3135 1.0 3212116 TimTec1_007852 NC1=C(C(=O)CN1c2ccccc2)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E21 compound treatment 0.312 0.0625 3.36 3.3603 1.0 3086880 TimTec1_007853 FC(F)(F)c1cccc(NC(=O)CC2COc3ccccc3O2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E22 compound treatment 0.269 0.0195 1.05 1.0496 1.0 3212117 TimTec1_007854 Cc1cc(Nc2ccc(O)cc2)c3ccccc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E23 mock treatment 0.25 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 E24 mock treatment 0.266 0.0165 0.89 0.8884 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F01 compound treatment 0.301 0.0515 2.77 2.7692 1.0 3212118 TimTec1_007855 Fc1cnc(Nc2ccc3OCOc3c2)nc1Nc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F02 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1530427 TimTec1_007856 O=S1(=O)CC(C(C1)N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F03 compound treatment 0.3 0.0505 2.72 2.7154 1.0 3212119 TimTec1_007857 O=C(CS(=O)(=O)Cc1ccccc1)Nc2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F04 compound treatment 0.338 0.0885 4.76 4.7575 1.0 1445255 TimTec1_007858 Cc1sc2ncn(Cc3ccccc3C)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F05 compound treatment 0.28 0.0305 1.64 1.6407 1.0 3212120 TimTec1_007859 CC(C)(C)c1ccc(cc1)C(=O)NCCCn2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F06 compound treatment 0.509 0.26 13.95 13.9467 1.0 3086881 TimTec1_007860 O=C(Nc1nc2ccccc2s1)C3CN(C(=O)C3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F07 compound treatment 0.422 0.173 9.27 9.2715 1.0 1530603 TimTec1_007861 COc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F08 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3212121 TimTec1_007862 CCN1CCN(CC1)c2ccc(NC(=O)C(C)C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F09 compound treatment 0.282 0.0325 1.75 1.7482 1.0 3086882 TimTec1_007863 Cc1cc(NC(=O)COC(=O)c2ccccn2)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F10 compound treatment 0.468 0.219 11.74 11.7434 1.0 1672981 TimTec1_007864 CCOC(=O)c1sc2ncn(C(C)C(=O)OCc3ccccc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F11 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 3086883 TimTec1_007865 CN1CCCC(C1)OC(=O)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F12 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3212122 TimTec1_007866 NC(=O)c1cnn2c(cc(nc12)c3ccc(F)cc3)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F13 compound treatment 0.435 0.186 9.97 9.9701 1.0 1446085 TimTec1_007867 O=C(CCc1ccccc1)NCCc2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F14 compound treatment 0.294 0.0445 2.39 2.393 1.0 3212123 TimTec1_007868 CCOC(=O)c1cnc2ccc(F)cc2c1NCc3cccnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F15 compound treatment 0.274 0.0245 1.32 1.3183 1.0 1185524 TimTec1_007869 COc1ccc(CCNc2nccc(=O)[nH]2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F16 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3086884 TimTec1_007870 O=C(Nc1nncs1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F17 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3086934 TimTec1_007871 Nc1cc(ccc1NCC2CCCO2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F18 compound treatment 0.271 0.0215 1.16 1.157 1.0 1657481 TimTec1_007872 Cc1sc2ncnc(NCC(=O)O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F19 compound treatment 0.251 0.00153 0.08 0.0823 1.0 1451450 TimTec1_007873 CC1CC(Nc2ccc(C)cc2)c3ccc(C)cc3N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F20 compound treatment 0.278 0.0285 1.53 1.5332 1.0 3086935 TimTec1_007874 COc1ccc2ncc(C(=O)NC3CCCC3)c(Cl)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F21 compound treatment 0.26 0.0105 0.57 0.5659 1.0 3086936 TimTec1_007875 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Br)cc3)C(=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F22 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3086937 TimTec1_007876 CCOC(=O)c1cc(CN2CCOCC2)c(C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F23 mock treatment 0.256 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 F24 mock treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G01 compound treatment 0.234 -0.0155 -0.83 -0.8313 -1.0 1620505 TimTec1_007877 CCN1CC(C)C(O)(CC1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G02 compound treatment 0.454 0.205 10.99 10.9911 1.0 3086938 TimTec1_007878 CN(c1nc(cs1)c2cccnc2)c3ccc(O)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G03 compound treatment 0.318 0.0685 3.68 3.6827 1.0 1423365 TimTec1_007879 COc1ccc(CC(=O)Nc2nccs2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G04 compound treatment 0.257 0.00753 0.4 0.4047 1.0 1877456 TimTec1_007880 COc1cc(OC)c(cc1OC)C(=O)N2CCN(CC2)c3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G05 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3086939 TimTec1_007881 CCOC(=O)Cn1cnc2ccccc2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G06 compound treatment 0.39 0.141 7.55 7.5519 1.0 3212124 TimTec1_007882 CC(c1ccc(C)cc1)n2cc(nn2)C(=O)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G07 compound treatment 0.26 0.0105 0.57 0.5659 1.0 3086940 TimTec1_007883 Cn1nnc2cc(ccc12)C(=O)NC3CC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G08 compound treatment 0.327 0.0775 4.17 4.1664 1.0 3212125 TimTec1_007884 CC(C(=O)NCCN1CCOCC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G09 compound treatment 0.277 0.0275 1.48 1.4795 1.0 3086941 TimTec1_007885 CC(Sc1ccc(Cl)cc1)C(=O)NCc2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G10 compound treatment 0.434 0.185 9.92 9.9163 1.0 1356547 TimTec1_007886 CC(OC(=O)c1ccc2ccccc2n1)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G11 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3086942 TimTec1_007887 O=C(Cn1c(=O)sc2ccccc12)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G12 compound treatment 0.279 0.0295 1.59 1.5869 1.0 3212126 TimTec1_007888 OC(=O)CCc1c(cc2ccccn12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G13 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3086943 TimTec1_007889 Clc1ccc(cc1)C2(CCCC2)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G14 compound treatment 0.34 0.0905 4.86 4.865 1.0 3212127 TimTec1_007890 O(c1ccccc1)c2ccc(cc2)n3cnnn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G15 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3212128 TimTec1_007891 CCCNC(=O)C1CCN(CC1)C(=O)c2ccc(cc2)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G16 compound treatment 0.488 0.239 12.82 12.8182 1.0 3086944 TimTec1_007892 CC(C)C(=O)Nc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G17 compound treatment 0.374 0.125 6.69 6.692 1.0 1141486 TimTec1_007893 COc1ccc(cc1)c2csc(n2)C(=C3CCCCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G18 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3086945 TimTec1_007894 CC(c1ccc(F)cc1)n2cc(nn2)C(=O)NCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G19 compound treatment 0.378 0.129 6.91 6.907 1.0 1848000 TimTec1_007895 Cc1cccc(NC(=O)CSc2ccccn2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G20 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 1391065 TimTec1_007896 OC(=O)C1CCCN1c2ncnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G21 compound treatment 0.457 0.208 11.15 11.1523 1.0 3086946 TimTec1_007897 CCOc1ccc(cc1)c2cnc(N)s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G22 compound treatment 0.346 0.0965 5.19 5.1874 1.0 1231110 TimTec1_007898 Clc1ccc(cc1)C(=O)Cn2cnc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G23 mock treatment 0.263 0.0135 0.73 0.7271 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 G24 mock treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H01 compound treatment 0.274 0.0245 1.32 1.3183 1.0 3212129 TimTec1_007899 Oc1cccc(Nc2nc(NCC3CCCO3)c4ccccc4n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H02 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 1270407 TimTec1_007900 CN(C1CCS(=O)(=O)C1)C(=O)c2ccccc2C(=O)N(C)C3CCS(=O)(=O)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H03 compound treatment 0.458 0.209 11.21 11.206 1.0 3086947 TimTec1_007901 CCOC(=O)c1ccc2nc(NC(=O)COC(=O)c3ccnn3C)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H04 compound treatment 0.36 0.111 5.94 5.9397 1.0 1714833 TimTec1_007902 COC(=O)c1sc2ncn(Cc3ccc(C)cc3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H05 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 1510758 TimTec1_007903 Fc1cccc(c1)C(=O)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H06 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1201896 TimTec1_007904 COc1cccc(c1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H07 compound treatment 0.36 0.111 5.94 5.9397 1.0 1221015 TimTec1_007905 Clc1ccc(SCC(=O)Nc2ccc(NC(=O)c3ccco3)cc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H08 compound treatment 0.286 0.0365 1.96 1.9631 1.0 3212130 TimTec1_007906 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H09 compound treatment 0.314 0.0645 3.47 3.4678 1.0 3212131 TimTec1_007907 COC(=O)c1c(C)n(Cc2ccccc2)c3ccc(O)cc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H10 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1197980 TimTec1_007908 CC(C(=O)O)n1cnc2sc(C)c(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H11 compound treatment 0.502 0.253 13.57 13.5705 1.0 3212132 TimTec1_007909 Cn1c(nc2cc(N)ccc12)c3ccc4nc([nH]c4c3)c5ccc(N)cc5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H12 compound treatment 0.229 -0.0205 -1.1 -1.0999 -1.0 3086948 TimTec1_007910 OC(=O)CCCn1nc(c2CCCCCc21)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H13 compound treatment 0.516 0.267 14.32 14.3228 1.0 1451319 TimTec1_007911 NC(=O)c1cc(sc1NC(=O)c2ccco2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H14 compound treatment 0.228 -0.0215 -1.15 -1.1537 -1.0 3086949 TimTec1_007912 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H15 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1397485 TimTec1_007913 CC1CN(Cc2ccc(C#N)cc2Cl)CC(C)O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H16 compound treatment 0.268 0.0185 1.0 0.9958 1.0 3086950 TimTec1_007914 Cc1nn(c2ccc(C)c(C)c2)c3oc(=O)cc(C)c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H17 compound treatment 0.313 0.0635 3.41 3.414 1.0 3212198 TimTec1_007915 Clc1ccc(cc1)N2C(=O)CC(SCc3nc4ccccc4[nH]3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H18 compound treatment 0.27 0.0205 1.1 1.1033 1.0 1414950 TimTec1_007916 CCc1ccc(cc1)c2csc3ncn(CC(=O)N)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H19 compound treatment 0.3 0.0505 2.72 2.7154 1.0 1788367 TimTec1_007917 Cc1cc(C)nc(NS(=O)(=O)c2ccc(cc2)n3cccc3)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H20 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3212199 TimTec1_007918 COc1ccc2ncc(C(=O)N3CCOCC3)c(Cl)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H21 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 3086951 TimTec1_007919 OC(=O)C1CC(=O)N=C(Nc2nc3ccccc3s2)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H22 compound treatment 0.314 0.0645 3.47 3.4678 1.0 3212200 TimTec1_007920 CC(C)(C)NC(=O)c1ccc2snnc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H23 mock treatment 0.252 0.00253 0.14 0.136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 H24 mock treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I01 compound treatment 0.222 -0.0275 -1.48 -1.4761 -1.0 3086952 TimTec1_007921 CC1CN(Cc2ccccc2)C(C)CC1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I02 compound treatment 0.265 0.0155 0.83 0.8346 1.0 1162910 TimTec1_007922 CNC(=O)c1c(O)c2cccc3CCCn(c1=O)c32 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I03 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 1008293 TimTec1_007923 CCN(CC)C(=O)c1ccc2OCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I04 compound treatment 0.504 0.255 13.68 13.678 1.0 1846984 TimTec1_007924 CCc1nnc(NC(=O)c2sc3nc4CCCCc4cc3c2N)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I05 compound treatment 0.272 0.0225 1.21 1.2108 1.0 1303764 TimTec1_007925 Brc1ccc2ncnc(NCC3CCCO3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I06 compound treatment 0.289 0.0395 2.12 2.1243 1.0 3086953 TimTec1_007926 CC(c1ccc(C)cc1)n2cc(nn2)C(=O)NCc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I07 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3212201 TimTec1_007927 Cn1nnc2cc(ccc12)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I08 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3212202 TimTec1_007928 CC(C(=O)NCCCn1ccnc1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I09 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3086954 TimTec1_007929 CCC(=O)c1cn(CC(=O)NC2CCCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I10 compound treatment 0.277 0.0275 1.48 1.4795 1.0 1690696 TimTec1_007930 COc1ccc2oc(=O)c(cc2c1)C(=O)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I11 compound treatment 0.439 0.19 10.19 10.185 1.0 3086955 TimTec1_007931 O=S1(=O)N=C(Nc2nc(cs2)c3ccccc3)c4ccccc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I12 compound treatment 0.296 0.0465 2.5 2.5005 1.0 3212203 TimTec1_007932 C(c1ccccc1)n2c(nc3ccccc23)C4CC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I13 compound treatment 0.339 0.0895 4.81 4.8112 1.0 1152223 TimTec1_007933 COc1ccc(NC(=O)c2ccco2)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I14 compound treatment 0.262 0.0125 0.67 0.6734 1.0 3212204 TimTec1_007934 CCOC(=O)C1=C(C)N(CC=C)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I15 compound treatment 0.288 0.0385 2.07 2.0706 1.0 3212205 TimTec1_007935 COc1cc(C#N)ccc1OCc2nc(no2)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I16 compound treatment 0.547 0.298 15.99 15.9887 1.0 3086956 TimTec1_007936 CCC(=O)Nc1ccc(cc1)c2cc3ccccc3oc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I17 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1481021 TimTec1_007937 CC1(C)C2CCC(C2)(C(=O)N3CCOCC3)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I18 compound treatment 0.409 0.16 8.57 8.5729 1.0 1184905 TimTec1_007938 COC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I19 compound treatment 0.257 0.00753 0.4 0.4047 1.0 1216188 TimTec1_007939 CC(C)c1cccc(C(C)C)c1NC(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I20 compound treatment 0.357 0.108 5.78 5.7785 1.0 3212206 TimTec1_007940 O=C(OCCNc1nc(nc2ccccc12)c3ccccc3)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I21 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3086957 TimTec1_007941 CC(C)NC(=O)C1(CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I22 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3212207 TimTec1_007942 CC(c1ccccc1)n2cnc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I23 mock treatment 0.237 -0.0125 -0.67 -0.67 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 I24 mock treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J01 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3086958 TimTec1_007943 CC1CCc2cc(F)cc3c(O)c(C(=O)Nc4ccccn4)c(=O)n1c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J02 compound treatment 0.261 0.0115 0.62 0.6197 1.0 1219265 TimTec1_007944 NC(=O)Cc1cc2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J03 compound treatment 0.266 0.0165 0.89 0.8884 1.0 1539977 TimTec1_007945 COc1ccc(NC2CS(=O)(=O)CC2NCc3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J04 compound treatment 0.376 0.127 6.8 6.7995 1.0 1153064 TimTec1_007946 CCC(C(=O)OC)n1cnc2sc(C(=O)Nc3ccccc3)c(C)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J05 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3212208 TimTec1_007947 COc1ccc(cc1)C(=O)OC2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J06 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3086959 TimTec1_007948 COC(=O)c1sc(NC(=O)c2ccccc2)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J07 compound treatment 0.537 0.288 15.45 15.4513 1.0 1262960 TimTec1_007949 COc1ccc(OCC(=O)Nc2cccc(NC(=O)c3ccco3)c2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J08 compound treatment 0.379 0.13 6.96 6.9607 1.0 3212209 TimTec1_007950 CCc1ccc(cc1)C(=O)Nc2nnn(CC)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J09 compound treatment 0.4 0.151 8.09 8.0892 1.0 3086960 TimTec1_007951 Cc1cc(N)n2nc(cc2n1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J10 compound treatment 0.281 0.0315 1.69 1.6944 1.0 1408804 TimTec1_007952 NC(=O)Cn1cnc2sc3CCCc3c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J11 compound treatment 0.339 0.0895 4.81 4.8112 1.0 3086961 TimTec1_007953 COc1ccc(OC2C(N(Cc3ccc4OCOc4c3)C2=O)c5cccs5)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J12 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3087005 TimTec1_007954 C(Nc1ccccn1)c2cccc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J13 compound treatment 0.427 0.178 9.54 9.5402 1.0 1398714 TimTec1_007955 CCOc1ccc(cc1)c2csc(NC(=O)CC)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J14 compound treatment 0.258 0.00853 0.46 0.4585 1.0 3087006 TimTec1_007956 Clc1ccc(CC(=O)NCCCn2ccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J15 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 3087007 TimTec1_007957 CC1(CC1)c2ccccc2NC(=O)c3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J16 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3087008 TimTec1_007958 C(N1CCCCC1)c2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J17 compound treatment 0.367 0.118 6.32 6.3159 1.0 1535568 TimTec1_007959 COc1ccccc1OCc2nc(no2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J18 compound treatment 0.495 0.246 13.19 13.1943 1.0 1410331 TimTec1_007960 COc1ccc(CCN2CC(=O)C(=C2N)c3nc4ccccc4s3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J19 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087009 TimTec1_007961 Cc1ccc(O)c(NC(=O)c2cccs2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J20 compound treatment 0.273 0.0235 1.26 1.2645 1.0 3087010 TimTec1_007962 Cc1c(sc2ncn(C)c(=O)c12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J21 compound treatment 0.364 0.115 6.15 6.1547 1.0 3212210 TimTec1_007963 Cn1c(NC2CC(=O)N(C2=O)c3ccc(Cl)cc3Cl)cc(=O)n(C)c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J22 compound treatment 0.561 0.312 16.74 16.741 1.0 3087011 TimTec1_007964 Cc1c(sc2nc[nH]c(=O)c12)C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J23 mock treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 J24 mock treatment 0.237 -0.0125 -0.67 -0.67 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K01 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 3212211 TimTec1_007965 CC(=O)Nc1ccccc1c2ccc(C)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K02 compound treatment 0.262 0.0125 0.67 0.6734 1.0 1741002 TimTec1_007966 Oc1c(C(=O)Nc2ccc(Cl)cc2Cl)c(=O)n(Cc3ccco3)c4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K03 compound treatment 0.276 0.0265 1.43 1.4257 1.0 3087012 TimTec1_007967 O=C(Nc1nncs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K04 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3212212 TimTec1_007968 CCOc1cc(cc(OCC)c1OCC)c2nc(no2)c3ccc(C)nc3OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K05 compound treatment 0.252 0.00253 0.14 0.136 1.0 3087013 TimTec1_007969 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K06 compound treatment 0.326 0.0765 4.11 4.1126 1.0 3212213 TimTec1_007970 Clc1ccccc1Cn2c(=O)oc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K07 compound treatment 0.262 0.0125 0.67 0.6734 1.0 1136632 TimTec1_007971 Clc1ccc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K08 compound treatment 0.446 0.197 10.56 10.5612 1.0 3212214 TimTec1_007972 O=C(NCCCn1ccnc1)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K09 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3212215 TimTec1_007973 CCC(=O)c1cn(CC(=O)N2CCCC2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K10 compound treatment 0.425 0.176 9.43 9.4327 1.0 3087014 TimTec1_007974 C=CCc1cccc2cc(C(=O)NCC3CCCO3)c(=O)oc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K11 compound treatment 0.265 0.0155 0.83 0.8346 1.0 1305056 TimTec1_007975 Clc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K12 compound treatment 0.292 0.0425 2.29 2.2855 1.0 3087015 TimTec1_007976 CC(C)OC(=O)Cn1c(=O)oc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K13 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3212285 TimTec1_007977 O=C(Cc1ccccc1)N2CCC(CC2)C(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K14 compound treatment 0.485 0.236 12.66 12.657 1.0 3087016 TimTec1_007978 CCc1nn2cc(nc2s1)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K15 compound treatment 0.53 0.281 15.08 15.0752 1.0 3212286 TimTec1_007979 Clc1ccccc1OCC(=O)N2CCc3ccccc3C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K16 compound treatment 0.569 0.32 17.17 17.1709 1.0 1268638 TimTec1_007980 CCCC(=O)Nc1ccc(cc1)c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K17 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3212287 TimTec1_007981 OC(=O)c1cccnc1c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K18 compound treatment 0.459 0.21 11.26 11.2598 1.0 1430476 TimTec1_007982 COC(=O)c1cc(sc1NC(=O)C2CCCO2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K19 compound treatment 0.51 0.261 14.0 14.0004 1.0 1234211 TimTec1_007983 CCN(CC)C(=O)COc1cc2oc(=O)cc(CC)c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K20 compound treatment 0.483 0.234 12.55 12.5495 1.0 3212288 TimTec1_007984 O=C(Cc1ccccc1)Nc2nnc(s2)C3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K21 compound treatment 0.256 0.00653 0.35 0.351 1.0 3087017 TimTec1_007985 O=C(Nc1ccc2OCCOc2c1)C3(CCOCC3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K22 compound treatment 0.407 0.158 8.47 8.4654 1.0 3212289 TimTec1_007986 O=C(COC(=O)c1cnccn1)c2ccc3CCCCc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K23 mock treatment 0.256 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 K24 mock treatment 0.259 0.00953 0.51 0.5122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L01 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3212290 TimTec1_007987 Clc1ccc(cc1)N2C(=O)C=C(N3CCOCC3)C2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L02 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3087018 TimTec1_007988 C(N1CCC(CC1)N2CCCCC2)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L03 compound treatment 0.283 0.0335 1.8 1.8019 1.0 3212291 TimTec1_007989 O=C(NC1CCS(=O)(=O)C1)c2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L04 compound treatment 0.389 0.14 7.5 7.4981 1.0 1181051 TimTec1_007990 Cc1c(sc2ncn(CC(=O)N)c(=O)c12)C(=O)Nc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L05 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3212292 TimTec1_007991 CN1CCC(CC1)OC(=O)Cc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L06 compound treatment 0.324 0.0745 4.01 4.0052 1.0 1548607 TimTec1_007992 COC(=O)c1sc(NC(=O)COc2ccc(OC)cc2)c(C#N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L07 compound treatment 0.293 0.0435 2.34 2.3393 1.0 1562684 TimTec1_007993 COc1ccccc1CNC(=O)C2COc3ccccc3O2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L08 compound treatment 0.468 0.219 11.74 11.7434 1.0 3212293 TimTec1_007994 O=C(Nc1cccc2ncccc12)c3cc4ccccc4o3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L09 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3087019 TimTec1_007995 Cc1cc2ncc(C(=O)Nc3ccccc3)c(C)n2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L10 compound treatment 0.374 0.125 6.69 6.692 1.0 1358839 TimTec1_007996 O=c1n(Cc2ccccc2)cnc3sc4CCCCc4c13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L11 compound treatment 0.346 0.0965 5.19 5.1874 1.0 3087020 TimTec1_007997 OC(=O)c1cccc(NCc2ccc3OCOc3c2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L12 compound treatment 0.279 0.0295 1.59 1.5869 1.0 3212294 TimTec1_007998 CCOc1ccc2nc(Nc3ncc4C(=O)CCCc4n3)nc(C)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L13 compound treatment 0.335 0.0855 4.6 4.5963 1.0 1728999 TimTec1_007999 CC(Nc1ncnc2ccccc12)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L14 compound treatment 0.285 0.0355 1.91 1.9094 1.0 3087021 TimTec1_008000 CCCC(C)C(=O)Nc1nnc(C)s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L15 compound treatment 0.289 0.0395 2.12 2.1243 1.0 3212295 TimTec1_008001 COc1cc(cc(OC)c1OC)C(=O)OC2CSCC2NC(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L16 compound treatment 0.254 0.00453 0.24 0.2435 1.0 1295031 TimTec1_008002 Cc1ccc(cc1)c2csc3ncn(CC=C)c(=O)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L17 compound treatment 0.301 0.0515 2.77 2.7692 1.0 3212296 TimTec1_008003 Nc1nnnn1NCc2ccc(OCC=C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L18 compound treatment 0.269 0.0195 1.05 1.0496 1.0 1488995 TimTec1_008004 CC(NC(=O)c1ccc2[nH]cnc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L19 compound treatment 0.542 0.293 15.72 15.72 1.0 1871879 TimTec1_008005 CCNc1nnc(s1)c2ccccc2OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L20 compound treatment 0.427 0.178 9.54 9.5402 1.0 3212297 TimTec1_008006 COc1ccccc1NC(=O)Cn2cnc3sc(C(=O)OC(C)C)c(C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L21 compound treatment 0.289 0.0395 2.12 2.1243 1.0 1191843 TimTec1_008007 CC(=O)Nc1cc2nn(nc2cc1C)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L22 compound treatment 0.269 0.0195 1.05 1.0496 1.0 3212298 TimTec1_008008 NC(=O)Cn1cc(C(=O)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L23 mock treatment 0.25 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 L24 mock treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M01 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3087022 TimTec1_008009 COC(=O)C1C2OC3(CN(C(c4ccccc4)c5ccccc5)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M02 compound treatment 0.347 0.0975 5.24 5.2411 1.0 3212299 TimTec1_008010 CCc1cc2c(NC3CCCC3)ncnc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M03 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3212300 TimTec1_008011 O=C(NCC1CCCO1)C2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M04 compound treatment 0.395 0.146 7.82 7.8205 1.0 3087023 TimTec1_008012 CCOc1nc(C)ccc1c2noc(n2)c3cccc(C)c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M05 compound treatment 0.273 0.0235 1.26 1.2645 1.0 3212301 TimTec1_008013 Fc1ccc(cc1)C(=O)OCC(=O)Nc2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M06 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3087024 TimTec1_008014 FC(F)(F)Oc1ccc(NC(=O)C2=NCCN2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M07 compound treatment 0.388 0.139 7.44 7.4444 1.0 1398079 TimTec1_008015 COc1ccc(NC(=O)C(C)NC(=O)c2ccccc2NC(=O)c3ccco3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M08 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 3212302 TimTec1_008016 CC(C(=O)N1CCCCCC1)(c2ccccc2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M09 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3087025 TimTec1_008017 CCC(=O)c1cn(CC(=O)N2CCc3ccccc23)c4ccccc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M10 compound treatment 0.286 0.0365 1.96 1.9631 1.0 3212303 TimTec1_008018 Clc1ccc2oc(=O)c(cc2c1)C(=O)NCCC3=CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M11 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3087026 TimTec1_008019 O=S1(=O)N=C(NCc2ccco2)c3ccccc31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M12 compound treatment 0.348 0.0985 5.29 5.2949 1.0 3212304 TimTec1_008020 CCc1ccc(NC(=O)CCc2ccc(C)o2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M13 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3087027 TimTec1_008021 CN1CCN(CC1)C(=O)CNS(=O)(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M14 compound treatment 0.428 0.179 9.59 9.5939 1.0 3212305 TimTec1_008022 Cc1nc2ccc(cc2nc1C)C(=O)OCC(=O)c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M15 compound treatment 0.377 0.128 6.85 6.8533 1.0 3087028 TimTec1_008023 Fc1ccc(cc1)C(=O)COC(=O)Cc2c[nH]c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M16 compound treatment 0.258 0.00853 0.46 0.4585 1.0 1683207 TimTec1_008024 COc1ccc(cc1OC)n2cnc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M17 compound treatment 0.504 0.255 13.68 13.678 1.0 1652913 TimTec1_008025 CN(C(=O)CCc1nc2ccccc2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M18 compound treatment 0.274 0.0245 1.32 1.3183 1.0 1732533 TimTec1_008026 CCOC(=O)c1cnc2ccccc2c1NCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M19 compound treatment 0.49 0.241 12.93 12.9256 1.0 1566325 TimTec1_008027 CCOC(=O)C1CCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M20 compound treatment 0.413 0.164 8.79 8.7878 1.0 3087029 TimTec1_008028 Oc1c2CN(Cc3ccccc3)CCc2nc4nnnn14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M21 compound treatment 0.4 0.151 8.09 8.0892 1.0 3212306 TimTec1_008029 Cc1ccc(NC(=O)CC2COc3ccccc3O2)cc1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M22 compound treatment 0.392 0.143 7.66 7.6593 1.0 3087030 TimTec1_008030 CCC(=O)Nc1ccc2nc([nH]c2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M23 mock treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 M24 mock treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N01 compound treatment 0.267 0.0175 0.94 0.9421 1.0 1344636 TimTec1_008031 Cc1ccc2n3CCN(C4CCO4)C5CCCc(c53)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N02 compound treatment 0.306 0.0565 3.04 3.0379 1.0 1223236 TimTec1_008032 CCCC(=O)c1cn(CC(=O)OC)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N03 compound treatment 0.3 0.0505 2.72 2.7154 1.0 3212369 TimTec1_008033 O=c1sc2ccccc2n1Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N04 compound treatment 0.331 0.0815 4.38 4.3813 1.0 1413258 TimTec1_008034 CC1CCN(CC1)C(=O)Cn2cnc3sc(C(=O)Nc4ccccc4)c(C)c3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N05 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3087031 TimTec1_008035 O=C(Cc1ccccc1)OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N06 compound treatment 0.308 0.0585 3.15 3.1453 1.0 1462249 TimTec1_008036 O=c1[nH]c2ccc(Oc3ccc4[nH]c(=O)c(=O)[nH]c4c3)cc2[nH]c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N07 compound treatment 0.454 0.205 10.99 10.9911 1.0 1786652 TimTec1_008037 O=C(C1COc2ccccc2O1)N3CCc4ccccc4C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N08 compound treatment 0.314 0.0645 3.47 3.4678 1.0 3087059 TimTec1_008038 COC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc(F)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N09 compound treatment 0.314 0.0645 3.47 3.4678 1.0 3087060 TimTec1_008039 CCc1cc(=O)n2nc(C)c(c3ccccc3OC)c2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N10 compound treatment 0.322 0.0725 3.9 3.8977 1.0 3087061 TimTec1_008040 CCOC(=O)c1sc2ncn(CC(=O)OC)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N11 compound treatment 0.274 0.0245 1.32 1.3183 1.0 3087062 TimTec1_008041 CCCn1nnnc1NCc2ccc(cc2)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N12 compound treatment 0.269 0.0195 1.05 1.0496 1.0 3087063 TimTec1_008042 Cn1ncc2c(Nc3ccccc3)ncnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N13 compound treatment 0.454 0.205 10.99 10.9911 1.0 3087064 TimTec1_008043 Clc1ccc(OCCCC(=O)N2CCCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N14 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3087065 TimTec1_008044 Fc1cccc(c1)C(=O)Nc2ncccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N15 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 3087066 TimTec1_008045 Cc1ccc(cc1)C2CC(=C3C(Nc4ccccc4N=C3C2)c5cccnc5)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N16 compound treatment 0.376 0.127 6.8 6.7995 1.0 1678072 TimTec1_008046 COC(=O)C(C)n1cnc2scc(c3ccc(OC)cc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N17 compound treatment 0.306 0.0565 3.04 3.0379 1.0 3087067 TimTec1_008047 OC(=O)CCCC(=O)Nc1cccc(NC(=O)c2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N18 compound treatment 0.508 0.259 13.89 13.8929 1.0 1723066 TimTec1_008048 CCCOC(=O)Nc1sc2CCCc2c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N19 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3212370 TimTec1_008049 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(cc3)C(F)(F)F)C(=O)N4CCOCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N20 compound treatment 0.363 0.114 6.1 6.1009 1.0 3087068 TimTec1_008050 O=C(Nc1ccc(cc1)N2CCOCC2)c3nc4ccccc4s3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N21 compound treatment 0.389 0.14 7.5 7.4981 1.0 3087069 TimTec1_008051 Brc1ccc(COC(=O)c2cccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N22 compound treatment 0.455 0.206 11.04 11.0448 1.0 3212371 TimTec1_008052 COc1cc2c(C(=O)O)c(C)n(C)c2cc1Br 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N23 mock treatment 0.253 0.00353 0.19 0.1898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 N24 mock treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O01 compound treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 3212372 TimTec1_008053 CCOC(=O)C1C2OC3(CN(Cc4ccc(C)cc4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O02 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 1226227 TimTec1_008054 COc1ccccc1OCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O03 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1257135 TimTec1_008055 CC(C)(C)C(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O04 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3087070 TimTec1_008056 COCC(=O)N(Cc1cc2cccc(C)c2nc1O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O05 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1217386 TimTec1_008057 COc1ccccc1c2coc3c(CN(C)C4CCCCC4)c(O)ccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O06 compound treatment 0.258 0.00853 0.46 0.4585 1.0 1319384 TimTec1_008058 C=CCn1c(CNC(=O)c2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O07 compound treatment 0.271 0.0215 1.16 1.157 1.0 1357487 TimTec1_008059 Cc1ccc(cc1)c2csc3ncnc(NCCO)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O08 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3087071 TimTec1_008060 Cc1sc(c(C(=O)O)c1C)n2cccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O09 compound treatment 0.494 0.245 13.14 13.1406 1.0 3212373 TimTec1_008061 CCC(=O)c1cn(Cc2ccccc2C#N)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O10 compound treatment 0.498 0.249 13.36 13.3555 1.0 3087072 TimTec1_008062 COc1ccc2oc(=O)c(cc2c1)C(=O)NC3CCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O11 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3212374 TimTec1_008063 CCc1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O12 compound treatment 0.252 0.00253 0.14 0.136 1.0 3087073 TimTec1_008064 COC(=O)Cn1c(=O)sc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O13 compound treatment 0.263 0.0135 0.73 0.7271 1.0 3212375 TimTec1_008065 Cc1nc2ccccc2c(=O)n1c3ccc(Cl)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O14 compound treatment 0.493 0.244 13.09 13.0869 1.0 3087074 TimTec1_008066 O=C(COC(=O)c1ccncc1)c2ccc3ccccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O15 compound treatment 0.286 0.0365 1.96 1.9631 1.0 3212376 TimTec1_008067 CN(C)c1ncnc2sc(C)c(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O16 compound treatment 0.256 0.00653 0.35 0.351 1.0 1595494 TimTec1_008068 C(C1COc2ccccc2N1)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O17 compound treatment 0.265 0.0155 0.83 0.8346 1.0 1719142 TimTec1_008069 CC1(C)C2(C)CCC1(CC2=O)C(=O)Nc3ccc(Cl)cn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O18 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3212377 TimTec1_008070 Cc1cc(Cl)ccc1NC(=O)COC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O19 compound treatment 0.266 0.0165 0.89 0.8884 1.0 3212378 TimTec1_008071 COc1ccc(cc1)C2(CCCC2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O20 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3087075 TimTec1_008072 C(N1CCCCCC1)c2nc3ccccc3[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O21 compound treatment 0.292 0.0425 2.29 2.2855 1.0 3212379 TimTec1_008073 CCOC(=O)N1CCC2(CC1)C(=C(N)OC3=C2C(=O)CCC3)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O22 compound treatment 0.284 0.0345 1.86 1.8556 1.0 3087076 TimTec1_008074 CC(C)c1nc2cc(NC(=O)C3CCCCC3)ccc2[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O23 mock treatment 0.265 0.0155 0.83 0.8346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 O24 mock treatment 0.256 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P01 compound treatment 0.374 0.125 6.69 6.692 1.0 3212380 TimTec1_008075 CCOCC(=O)N1CCc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P02 compound treatment 0.356 0.107 5.72 5.7248 1.0 3212381 TimTec1_008076 NC1=C(C#N)C2(CCN(Cc3ccccc3)CC2)C(=C4Nc5ccccc5N41)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P03 compound treatment 0.253 0.00353 0.19 0.1898 1.0 1118497 TimTec1_008077 OC1CS(=O)(=O)CC1Nc2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P04 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1599062 TimTec1_008078 O=C(Cn1cnc2scc(c3ccccc3)c2c1=O)N4CCCCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P05 compound treatment 0.446 0.197 10.56 10.5612 1.0 3087077 TimTec1_008079 CC1CCN(CC1)C(=O)c2cc3ccccc3o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P06 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3212382 TimTec1_008080 CCCOC(=O)c1ccc(cc1)n2nc(c3c(C)cc(=O)oc23)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P07 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087078 TimTec1_008081 CCc1ccc(CN2CCC(CC2)N3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P08 compound treatment 0.374 0.125 6.69 6.692 1.0 3212383 TimTec1_008082 CCCNC(=O)c1cnn2c(C)cc(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P09 compound treatment 0.334 0.0845 4.54 4.5425 1.0 1549606 TimTec1_008083 Clc1ccc2oc(=O)n(CN3CCCCC3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P10 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3212384 TimTec1_008084 CCn1cnc2scc(c3ccccc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P11 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3087079 TimTec1_008085 COc1cc(CNCc2cccnc2)ccc1OCC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P12 compound treatment 0.374 0.125 6.69 6.692 1.0 3212385 TimTec1_008086 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)NC3CCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P13 compound treatment 0.386 0.137 7.34 7.3369 1.0 3212386 TimTec1_008087 Cc1sc2ncn(CC(=O)OC3CCCCC3)c(=O)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P14 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3087080 TimTec1_008088 Cc1ccc(CC(=O)N2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P15 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 3212387 TimTec1_008089 COC(=O)C1C(C)CC2=C(C(Nc3ccccc3N2)c4ccccc4C)C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P16 compound treatment 0.341 0.0915 4.92 4.9187 1.0 1622942 TimTec1_008090 CCCn1cnc2scc(c3ccc(OC)cc3)c2c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P17 compound treatment 0.602 0.353 18.94 18.9443 1.0 3212388 TimTec1_008091 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)C4CCCO4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P18 compound treatment 0.544 0.295 15.83 15.8275 1.0 3087081 TimTec1_008092 NC1=C(C(=O)CN1c2ccccc2)c3nc4ccccc4c(=O)[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P19 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3212389 TimTec1_008093 CCOc1cccc(c1)C2C(=CN(CC)C=C2C(=O)OC)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P20 compound treatment 0.341 0.0915 4.92 4.9187 1.0 3087082 TimTec1_008094 Cc1nc2ccc(NC(=O)N3CCSCC3)cc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P21 compound treatment 0.453 0.204 10.94 10.9373 1.0 3212390 TimTec1_008095 CC(C)OC(=O)c1ccc(COC(=O)CNC(=O)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P22 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3087083 TimTec1_008096 Fc1cccc(CNCC2CCCO2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P23 mock treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2085 P24 mock treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A01 compound treatment 0.226 -0.0235 -1.26 -1.2612 -1.0 3212391 TimTec1_008097 Cc1ccsc1CNCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A02 compound treatment 0.252 0.00253 0.14 0.136 1.0 3212454 TimTec1_008098 Clc1cccc(CN2CCC(CC2)C(=O)N(CC=C)CC=C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A03 compound treatment 0.308 0.0585 3.15 3.1453 1.0 3087084 TimTec1_008099 NC(=O)c1c(NC(=O)c2cc(on2)c3ccccc3)sc4CCCCc14 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A04 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 3212455 TimTec1_008100 Oc1ccccc1CNCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A05 compound treatment 0.23 -0.0195 -1.05 -1.0462 -1.0 3212456 TimTec1_008101 CNCC(O)Cn1c(nc2ccccc12)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A06 compound treatment 0.233 -0.0165 -0.88 -0.885 -1.0 3212457 TimTec1_008102 O=C(NCCc1ccccc1)C2CCN(CC2)C(=O)C(C(=O)c3ccccc3)n4ccccc4=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A07 compound treatment 0.376 0.127 6.8 6.7995 1.0 1688145 TimTec1_008103 CC(=O)Nc1cccc(c1)c2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A08 compound treatment 0.218 -0.0315 -1.69 -1.6911 -1.0 3087085 TimTec1_008104 Cc1c(sc2nc[nH]c(=O)c12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A09 compound treatment 0.265 0.0155 0.83 0.8346 1.0 1173874 TimTec1_008105 CCN1C(=O)C(C(=O)O)C(=O)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A10 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 3087086 TimTec1_008106 CC(NCC1OCc2ccccc2CO1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A11 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3212458 TimTec1_008107 CCCC1CCC(CC1)C2CCC(CC2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A12 compound treatment 0.286 0.0365 1.96 1.9631 1.0 1532351 TimTec1_008108 CC(C)(C)Oc1ccc(cc1)C(=O)N(Cc2ccc(F)cc2)C3CCOC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A13 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1359062 TimTec1_008109 CCOc1ccc2ncc(C(=O)O)c(O)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A14 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3212459 TimTec1_008110 CN(C)c1ccc(CNCCC2(CCOC(C)(C)C2)c3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A15 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1788332 TimTec1_008111 CCOc1ccc(NC(=O)C2C(C3OC2C=C3)C(=O)O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A16 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3212460 TimTec1_008112 CC1(C)CC(CC(C)(C)N1)NCc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A17 compound treatment 0.262 0.0125 0.67 0.6734 1.0 3087087 TimTec1_008113 COc1ccccc1C2=NOC(C2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A18 compound treatment 0.266 0.0165 0.89 0.8884 1.0 1394442 TimTec1_008114 Fc1ccc(CNCc2cccnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A19 compound treatment 0.435 0.186 9.97 9.9701 1.0 3212461 TimTec1_008115 Cc1ccc(Nc2nc(cs2)C(=O)N3CCCCC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A20 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3087088 TimTec1_008116 COc1ccc(CNCCN(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A21 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3087089 TimTec1_008117 CN1CCN(Cc2cn[nH]c2c3ccccc3)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A22 compound treatment 0.256 0.00653 0.35 0.351 1.0 3212462 TimTec1_008118 C(CN1CCOCC1)NCc2ccncc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A23 mock treatment 0.265 0.0155 0.83 0.8346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 A24 mock treatment 0.264 0.0145 0.78 0.7809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B01 compound treatment 0.263 0.0135 0.73 0.7271 1.0 1348556 TimTec1_008119 OC(=O)CNC(=O)COc1ccc(cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B02 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 3087090 TimTec1_008120 N#CNC1=NCN(CCN2CCOCC2)CN1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B03 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 1514480 TimTec1_008121 OC(=O)CCCC(=O)Nc1ccccc1N2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B04 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3087137 TimTec1_008122 COc1cccc(c1)C(=O)N2CCC(CC2)C(=O)N3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B05 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3087138 TimTec1_008123 CC1CCCCN1C(C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B06 compound treatment 0.268 0.0185 1.0 0.9958 1.0 3087139 TimTec1_008124 NC(=O)C1CCCN(C1)S(=O)(=O)c2ccc(Cl)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B07 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1468759 TimTec1_008125 CC1(C)CC(CCN)(Cc2ccccc2)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B08 compound treatment 0.274 0.0245 1.32 1.3183 1.0 3087140 TimTec1_008126 NC1=C(C#N)C(c2ccsc2)c3oc(CO)cc(=O)c3O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B09 compound treatment 0.256 0.00653 0.35 0.351 1.0 1583111 TimTec1_008127 Cc1cccc(Oc2ccc(NC(=O)CCCC(=O)O)cc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B10 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 3087141 TimTec1_008128 CCCC1C(=C(N)OC2=C1C(=O)CCC2)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B11 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1405409 TimTec1_008129 CCOC(=O)c1cn(C2CC2)c3c(F)c(F)c(F)cc3c1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B12 compound treatment 0.223 -0.0265 -1.42 -1.4224 -1.0 3212463 TimTec1_008130 CC(CCc1ccccc1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B13 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1179105 TimTec1_008131 OC(=O)C(CC(=O)Nc1ccccc1)C2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B14 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087142 TimTec1_008132 O=C(COc1ccccc1)NCCN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B15 compound treatment 0.258 0.00853 0.46 0.4585 1.0 3212464 TimTec1_008133 CC(Cc1ccccc1)NC(=O)c2cnc[nH]2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B16 compound treatment 0.262 0.0125 0.67 0.6734 1.0 3087143 TimTec1_008134 OC(=O)COCC(=O)Nc1ccc(Br)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B17 compound treatment 0.278 0.0285 1.53 1.5332 1.0 3212465 TimTec1_008135 CN(C)CC#CCN1CCCC2(CCOC(C)(C)C2)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B18 compound treatment 0.26 0.0105 0.57 0.5659 1.0 3087144 TimTec1_008136 Sc1nnc(CN2CCOCC2)n1c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B19 compound treatment 0.319 0.0695 3.74 3.7365 1.0 1605075 TimTec1_008137 CCCC(=O)c1cc(F)c(cc1C)N2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B20 compound treatment 0.266 0.0165 0.89 0.8884 1.0 3087145 TimTec1_008138 Cc1ccc(NC(=O)c2ccco2)c(N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B21 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3212466 TimTec1_008139 CC(C)(C)NC(=O)c1cc(NC(=O)C(F)(F)F)cc(NC(=O)C(F)(F)F)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B22 compound treatment 0.252 0.00253 0.14 0.136 1.0 1098688 TimTec1_008140 CCN(CC)Cc1c(C)nc2ccccc2c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B23 mock treatment 0.231 -0.0185 -0.99 -0.9925 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 B24 mock treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C01 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3212467 TimTec1_008141 OC(=O)c1cccc(NCc2ccncc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C02 compound treatment 0.277 0.0275 1.48 1.4795 1.0 3212468 TimTec1_008142 COc1cc(CN2CCC(CC2)C(=O)N3CCN(CC3)c4ccccc4F)cc(OC)c1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C03 compound treatment 0.455 0.206 11.04 11.0448 1.0 3087146 TimTec1_008143 CN(C1CCCCC1)C(=O)c2cc(on2)c3ccc(C)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C04 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3212469 TimTec1_008144 CCOC(=O)C1CCN(Cc2cccc(OC)c2O)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C05 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 1633390 TimTec1_008145 OC(=O)C1CCCN1S(=O)(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C06 compound treatment 0.393 0.144 7.71 7.7131 1.0 3212470 TimTec1_008146 CN(Cc1ccccc1)C(=O)c2csc(Nc3ccc(C)cc3)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C07 compound treatment 0.27 0.0205 1.1 1.1033 1.0 3087147 TimTec1_008147 CCNC(=O)c1sc(nc1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C08 compound treatment 0.271 0.0215 1.16 1.157 1.0 1420669 TimTec1_008148 OC(=O)C1Nc2ccccc2C3C=CCC31 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C09 compound treatment 0.267 0.0175 0.94 0.9421 1.0 3087148 TimTec1_008149 Cc1ccc(cc1)C(=O)C2CCOC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C10 compound treatment 0.263 0.0135 0.73 0.7271 1.0 1919750 TimTec1_008150 CC1=CCC(Cc2nc3ccccc3o2)C1(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C11 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1520076 TimTec1_008151 CCc1nc2ccccc2c(N)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C12 compound treatment 0.444 0.195 10.45 10.4537 1.0 1690846 TimTec1_008152 CC(=O)N(CCC(Cc1ccccc1)c2ccc3OCOc3c2)Cc4ccc5OCOc5c4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C13 compound treatment 0.254 0.00453 0.24 0.2435 1.0 1538543 TimTec1_008153 COC(=O)c1cc2ccccc2c(c1O)c3c(O)ccc4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C14 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 1456541 TimTec1_008154 COc1ccc(cc1)C(=O)N2CC(C)OC(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C15 compound treatment 0.271 0.0215 1.16 1.157 1.0 1530194 TimTec1_008155 Cc1c(C)c2cc(ccc2n1Cc3ccccc3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C16 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3212471 TimTec1_008156 CC1CCN(CC1)c2c(N)cccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C17 compound treatment 0.286 0.0365 1.96 1.9631 1.0 3087149 TimTec1_008157 OC(=O)C1CC(=NO1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C18 compound treatment 0.253 0.00353 0.19 0.1898 1.0 1649056 TimTec1_008158 Cc1ccccc1CNCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C19 compound treatment 0.399 0.15 8.04 8.0355 1.0 3212472 TimTec1_008159 COc1ccc(Nc2nc(cs2)C(=O)NCc3ccccc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C20 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3087150 TimTec1_008160 Cc1ccc(CNCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C21 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3212473 TimTec1_008161 CCN(CCO)Cc1cn[nH]c1c2ccc(C)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C22 compound treatment 0.256 0.00653 0.35 0.351 1.0 3087151 TimTec1_008162 Cc1ccc(CNCc2ccccc2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C23 mock treatment 0.26 0.0105 0.57 0.5659 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 C24 mock treatment 0.251 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D01 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1735820 TimTec1_008163 Cc1c(C#N)c2ccccc2n1CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D02 compound treatment 0.257 0.00753 0.4 0.4047 1.0 3212773 TimTec1_008164 Oc1ccc2ccccc2c1CNn3cnnc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D03 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1670020 TimTec1_008165 OC(=O)CCC(=O)N1CC(=O)Nc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D04 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 3087152 TimTec1_008166 Cc1ccc(cc1Cl)n2c(C)cc(C)c(C#N)c2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D05 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 3212774 TimTec1_008167 CC(C)c1nc2ccccc2n1C(C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D06 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3212775 TimTec1_008168 COc1cc2[nH]c(=O)c(C(=O)NCCCc3ccccc3)c(O)c2cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D07 compound treatment 0.412 0.163 8.73 8.7341 1.0 1444599 TimTec1_008169 NCCC(Cc1ccccc1)c2ccc3OCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D08 compound treatment 0.319 0.0695 3.74 3.7365 1.0 3212776 TimTec1_008170 NC(=O)COc1ccc(cc1Cl)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D09 compound treatment 0.33 0.0805 4.33 4.3276 1.0 3087153 TimTec1_008171 Clc1c(sc2ccccc12)C(=O)OCCN3CCOCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D10 compound treatment 0.272 0.0225 1.21 1.2108 1.0 1395566 TimTec1_008172 Oc1cc(=O)[nH]c2nc(Nc3ccccc3)sc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D11 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 1499067 TimTec1_008173 CC1(C)CC(=O)C=C(C1)NCc2ccc(cc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D12 compound treatment 0.216 -0.0335 -1.8 -1.7985 -1.0 3087154 TimTec1_008174 C(NC1CCCCCCC1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D13 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1050866 TimTec1_008175 OCC12COC(N2C(OC1)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D14 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3212777 TimTec1_008176 CC(CN1CCCC1)OC(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D15 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 1782464 TimTec1_008177 CC(=O)Nc1c(O)c2ccccc2oc1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D16 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3212778 TimTec1_008178 CC(=O)NC1C(=O)Nc2ccc(F)cc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D17 compound treatment 0.297 0.0475 2.55 2.5542 1.0 3087155 TimTec1_008179 Cc1nc2n(c(C)nc2s1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D18 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3212779 TimTec1_008180 CC(C)N1CC(CC1=O)C(=O)Nc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D19 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3087156 TimTec1_008181 COC(=O)c1ccccc1S(=O)(=O)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D20 compound treatment 0.454 0.205 10.99 10.9911 1.0 3212780 TimTec1_008182 CN(C)c1ccc(cc1)C(=O)OCC(=O)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D21 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3087157 TimTec1_008183 CC1CCN(Cc2ccc(N)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D22 compound treatment 0.272 0.0225 1.21 1.2108 1.0 1639443 TimTec1_008184 COc1ccc(cc1)c2csc3ncnc(NCCO)c23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D23 mock treatment 0.251 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 D24 mock treatment 0.231 -0.0185 -0.99 -0.9925 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E01 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3212781 TimTec1_008185 CC(N1CCOCC1)c2ccc(o2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E02 compound treatment 0.295 0.0455 2.45 2.4468 1.0 3087158 TimTec1_008186 CCN(Cc1ccccc1)C(=O)C2CCN(Cc3ccc(SC)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E03 compound treatment 0.406 0.157 8.41 8.4117 1.0 3212782 TimTec1_008187 CCN(CC)C(=O)c1cc(on1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E04 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3212783 TimTec1_008188 O=C(NCCc1ccccc1)C(C(=O)c2ccccc2)n3ccccc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E05 compound treatment 0.225 -0.0245 -1.31 -1.3149 -1.0 3087159 TimTec1_008189 CC1CCCCN1c2ccc(N)cc2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E06 compound treatment 0.29 0.0405 2.18 2.1781 1.0 3212784 TimTec1_008190 CCCCN(Cc1ccccc1)C(=O)C2CCN(Cc3cccc(O)c3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E07 compound treatment 0.383 0.134 7.18 7.1757 1.0 1203428 TimTec1_008191 OC(=O)CCC(=O)Nc1ccc(cc1)c2cn3ccccc3n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E08 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1244486 TimTec1_008192 C1C=CC2C1C(Nc3ccccc23)c4ccncc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E09 compound treatment 0.257 0.00753 0.4 0.4047 1.0 1581355 TimTec1_008193 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3cc(OC)c(OC(=O)C)c(OC)c3)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E10 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 1500942 TimTec1_008194 CC1CC(C)(C)OC(O1)C(C)(C)CN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E11 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1697639 TimTec1_008195 CC1=C(C(NC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OC3CCCCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E12 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 1171657 TimTec1_008196 CC(NCCN1CCNCC1)c2cc(cc3c2CCC3(C)C)C(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E13 compound treatment 0.256 0.00653 0.35 0.351 1.0 1214166 TimTec1_008197 COC(=O)c1c(N)sc2CN(C)CCc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E14 compound treatment 0.282 0.0325 1.75 1.7482 1.0 1046116 TimTec1_008198 COc1cc(CC=C)c(O)c(CC=C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E15 compound treatment 0.414 0.165 8.84 8.8416 1.0 1038723 TimTec1_008199 CCOC(=O)COc1ccc2c(C)cc(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E16 compound treatment 0.275 0.0255 1.37 1.372 1.0 3212785 TimTec1_008200 COc1ccc(CNCc2ccc(cc2)N(C)C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E17 compound treatment 0.419 0.17 9.11 9.1103 1.0 3087160 TimTec1_008201 OC(=O)c1cc(on1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E18 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3212786 TimTec1_008202 CCN1CCCC1CNCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E19 compound treatment 0.491 0.242 12.98 12.9794 1.0 3087161 TimTec1_008203 O=C(N1CCCCC1)c2csc(Nc3cccc4ccccc34)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E20 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3212787 TimTec1_008204 C=CCC(NCc1cccs1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E21 compound treatment 0.369 0.12 6.42 6.4234 1.0 3087162 TimTec1_008205 O=c1oc2ccccc2n1CCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E22 compound treatment 0.325 0.0755 4.06 4.0589 1.0 3212788 TimTec1_008206 Clc1ccc(OCC(=O)N2CCNCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E23 mock treatment 0.258 0.00853 0.46 0.4585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 E24 mock treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F01 compound treatment 0.46 0.211 11.31 11.3135 1.0 1861305 TimTec1_008207 COc1ccc(OCc2nnc(N)s2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F02 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087163 TimTec1_008208 Cc1ccc(O)c(CNn2cnnc2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F03 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3212789 TimTec1_008209 Cc1ccc(C)n1C(Cc2ccccc2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F04 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 3087164 TimTec1_008210 OC(=O)CCC(=O)Nc1ccc(cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F05 compound treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 3212790 TimTec1_008211 CC(C)CNC(=O)C1CCCCC1C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F06 compound treatment 0.254 0.00453 0.24 0.2435 1.0 1619307 TimTec1_008212 CCCC(=O)Nc1sc2c(CC(C)(C)NC2(C)C)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F07 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 1572925 TimTec1_008213 CC(C)c1cc(C(=O)O)n(n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F08 compound treatment 0.256 0.00653 0.35 0.351 1.0 3087197 TimTec1_008214 CC1CCN(CC1)c2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F09 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087198 TimTec1_008215 CC(C)c1ccc(cc1)C(=O)CCN(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F10 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3087199 TimTec1_008216 COC(=O)CC1=C(C(C(=C(N)O1)C#N)c2cccnc2)C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F11 compound treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 1226789 TimTec1_008217 NC(Cc1ccccc1)c2ccc3OCCOc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F12 compound treatment 0.429 0.18 9.65 9.6476 1.0 3087200 TimTec1_008218 Cc1cc(C)cc(OCC(=O)N2CCCC2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F13 compound treatment 0.275 0.0255 1.37 1.372 1.0 3087201 TimTec1_008219 COc1ccc2n3CCN=C(N)c3cc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F14 compound treatment 0.322 0.0725 3.9 3.8977 1.0 3087202 TimTec1_008220 Clc1ccc(OCC(=O)OCCN2CCOCC2)c(Cl)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F15 compound treatment 0.366 0.117 6.26 6.2621 1.0 3087203 TimTec1_008221 CCC(=O)c1[nH]c(C)c(C(=O)CC)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F16 compound treatment 0.363 0.114 6.1 6.1009 1.0 3212791 TimTec1_008222 Cc1ccc(SCCC(=O)N2CCC(CC2)C(=O)N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F17 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3087204 TimTec1_008223 Cc1ccc(NC(=O)C2(CCCC2)c3ccccc3)nc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F18 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3212792 TimTec1_008224 Cn1c(NCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F19 compound treatment 0.233 -0.0165 -0.88 -0.885 -1.0 3212793 TimTec1_008225 CCOc1ccc2[nH]c(=O)c(cc2c1)C(N3CCCCC3)c4nnnn4CCOC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F20 compound treatment 0.394 0.145 7.77 7.7668 1.0 3087205 TimTec1_008226 O=C(Cc1ccccc1)Nc2ccc3COC(=O)c3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F21 compound treatment 0.418 0.169 9.06 9.0565 1.0 3087206 TimTec1_008227 CN1CCc2nc3sc(C(=O)NC(C)(C)C)c(N)c3cc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F22 compound treatment 0.266 0.0165 0.89 0.8884 1.0 1361247 TimTec1_008228 CC1CCN(CC1)C(=O)Cn2cc(C#N)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F23 mock treatment 0.25 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 F24 mock treatment 0.226 -0.0235 -1.26 -1.2612 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G01 compound treatment 0.252 0.00253 0.14 0.136 1.0 3212794 TimTec1_008229 Cc1cc(O)c2n(Cc3ccccc3Cl)nc[n+]2n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G02 compound treatment 0.302 0.0525 2.82 2.8229 1.0 3087207 TimTec1_008230 CCN(Cc1ccccc1)C(=O)C2CCN(Cc3ccc(cc3)C(F)(F)F)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G03 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 3212795 TimTec1_008231 COC(=O)c1cc(no1)c2ccccn2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G04 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 3212865 TimTec1_008232 COc1ccc(Nc2nc(cs2)C(=O)N3CCN(C)CC3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G05 compound treatment 0.27 0.0205 1.1 1.1033 1.0 3087208 TimTec1_008233 OC(=O)CCN1Cc2ccccc2C1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G06 compound treatment 0.332 0.0825 4.44 4.4351 1.0 1455909 TimTec1_008234 Cc1nc2ccc(N)cc2c(O)c1CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G07 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3212866 TimTec1_008235 O=C(NCc1cccs1)C(C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G08 compound treatment 0.429 0.18 9.65 9.6476 1.0 1593691 TimTec1_008236 O=C(N1CCC(C1)c2ccccc2)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G09 compound treatment 0.327 0.0775 4.17 4.1664 1.0 1260979 TimTec1_008237 CCCCC1CCC(CC1)C2CCC(CC2)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G10 compound treatment 0.271 0.0215 1.16 1.157 1.0 3212867 TimTec1_008238 C(CC(c1ccco1)c2ccccc2)NCc3cccs3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G11 compound treatment 0.405 0.156 8.36 8.3579 1.0 3087209 TimTec1_008239 CCOc1ccc(Cc2c(Cl)nc(SC)nc2Cl)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G12 compound treatment 0.256 0.00653 0.35 0.351 1.0 3212868 TimTec1_008240 CCCC1CC(CCO1)c2csc(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G13 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1554032 TimTec1_008241 COc1ccc(Br)cc1CNc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G14 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 1199876 TimTec1_008242 CCC1(C)CC(CCO1)C(CCN)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G15 compound treatment 0.287 0.0375 2.02 2.0169 1.0 1627384 TimTec1_008243 C(CN1CCOCC1)Nc2nc(nc3ccccc23)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G16 compound treatment 0.267 0.0175 0.94 0.9421 1.0 3087210 TimTec1_008244 COc1ccc(CNCc2ccncc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G17 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3212869 TimTec1_008245 Cc1cc2c(ncnc2s1)N3CCC(CC3)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G18 compound treatment 0.258 0.00853 0.46 0.4585 1.0 1721079 TimTec1_008246 COc1ccc(NC(CC=C)c2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G19 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3212870 TimTec1_008247 CC(C)(C)NC(=O)C(C(=O)c1ccccc1)n2ccccc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G20 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1431012 TimTec1_008248 Clc1ccccc1CNCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G21 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3212871 TimTec1_008249 CN(Cc1ccccc1)Cc2ccccc2F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G22 compound treatment 0.255 0.00553 0.3 0.2972 1.0 3087211 TimTec1_008250 COc1cccc(CNCC(C)O)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G23 mock treatment 0.265 0.0155 0.83 0.8346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 G24 mock treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H01 compound treatment 0.262 0.0125 0.67 0.6734 1.0 1585571 TimTec1_008251 OC(=O)CSCC(=O)N1CCCCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H02 compound treatment 0.277 0.0275 1.48 1.4795 1.0 3212872 TimTec1_008252 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C32C(=O)N(CCc4ccccc4)c5ccccc53)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H03 compound treatment 0.252 0.00253 0.14 0.136 1.0 1125791 TimTec1_008253 O=C(C(c1ccccc1)c2ccccc2)N3CCNCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H04 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 3212873 TimTec1_008254 OC1=C(C(NC1=O)c2ccccc2)C(=O)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H05 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3087212 TimTec1_008255 OC(=O)CN1CCC(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H06 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3212874 TimTec1_008256 CC1(C)Cc2c(C#N)c(NC(=O)Cc3ccccc3)sc2C(C)(C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H07 compound treatment 0.451 0.202 10.83 10.8299 1.0 3087213 TimTec1_008257 CC(C)OC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H08 compound treatment 0.267 0.0175 0.94 0.9421 1.0 3212875 TimTec1_008258 CC(C)OC(=O)Cn1cc(C#N)c2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H09 compound treatment 0.263 0.0135 0.73 0.7271 1.0 1699078 TimTec1_008259 Oc1c(CN2CCOCC2)ccc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H10 compound treatment 0.303 0.0535 2.88 2.8767 1.0 3212876 TimTec1_008260 NC1=C(C#N)C2(C(=O)N(CCc3ccccc3)c4ccccc42)C(=C(N)S1)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H11 compound treatment 0.3 0.0505 2.72 2.7154 1.0 1431998 TimTec1_008261 Brc1ccc2n(CCC#N)c(=O)oc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H12 compound treatment 0.322 0.0725 3.9 3.8977 1.0 3212877 TimTec1_008262 CC1CCCC(C)N1C(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H13 compound treatment 0.251 0.00153 0.08 0.0823 1.0 1131527 TimTec1_008263 CC1(C)Cc2ccccc2C(CC=C)N1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H14 compound treatment 0.259 0.00953 0.51 0.5122 1.0 1862477 TimTec1_008264 CC(C)C(=O)Nc1ccc(CN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H15 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 1243642 TimTec1_008265 OC(=O)C(Cc1ccc(F)cc1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H16 compound treatment 0.422 0.173 9.27 9.2715 1.0 1432046 TimTec1_008266 CCc1cc2c(NCCO)ncnc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H17 compound treatment 0.258 0.00853 0.46 0.4585 1.0 1786471 TimTec1_008267 CN1CCN(CC2COc3ccccc3O2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H18 compound treatment 0.269 0.0195 1.05 1.0496 1.0 3087214 TimTec1_008268 C=CCn1c(NCc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H19 compound treatment 0.355 0.106 5.67 5.671 1.0 1125869 TimTec1_008269 Brc1ccc(OCC(=O)OCC(=O)c2ccccc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H20 compound treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 1178508 TimTec1_008270 CCC(=O)OC1(C(C)CN(C)CC1C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H21 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 3212878 TimTec1_008271 COCc1[nH]nc2OC(=C(C#N)C(c12)c3ccc(OCC(=O)N)c(OC)c3)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H22 compound treatment 0.385 0.136 7.28 7.2832 1.0 1513547 TimTec1_008272 COc1cccc2c(=O)c3n(C)ncc3n(C)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H23 mock treatment 0.25 5.31E-4 0.03 0.0285 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 H24 mock treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I01 compound treatment 0.272 0.0225 1.21 1.2108 1.0 1283957 TimTec1_008273 CC(=O)Nc1ccccc1c2nc3ccccc3s2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I02 compound treatment 0.23 -0.0195 -1.05 -1.0462 -1.0 3087215 TimTec1_008274 CC(C)NC(=O)C1CCN(Cc2ccc(C)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I03 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3212879 TimTec1_008275 COC(=O)c1cc(no1)c2ccccc2C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I04 compound treatment 0.545 0.296 15.88 15.8812 1.0 3212880 TimTec1_008276 Cc1ccc(Nc2nc(cs2)C(=O)N(CC=C)CC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I05 compound treatment 0.264 0.0145 0.78 0.7809 1.0 3087216 TimTec1_008277 OC(=O)CC(CC(=O)Nc1nncs1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I06 compound treatment 0.243 -0.00647 -0.35 -0.3476 -1.0 3212881 TimTec1_008278 OC(=O)c1cc(on1)c2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I07 compound treatment 0.257 0.00753 0.4 0.4047 1.0 3087217 TimTec1_008279 CCC(=O)Nc1cc(ccc1N2CCOCC2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I08 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 3212882 TimTec1_008280 CC(=O)OC1CCCCC1C2=CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I09 compound treatment 0.257 0.00753 0.4 0.4047 1.0 1632793 TimTec1_008281 Cc1sc2ncnc(Nc3ccccc3)c2c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I10 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3212883 TimTec1_008282 CCCCc1nc2ccccc2c(N)c1CC.OCC(O)C1OC(=O)C(=C1O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I11 compound treatment 0.306 0.0565 3.04 3.0379 1.0 1288391 TimTec1_008283 CC1CCCC(C1)OC(=O)C2=C(C)N(C)C(=O)NC2c3ccccc3Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I12 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3087218 TimTec1_008284 CCN(CC)CCCOc1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I13 compound treatment 0.36 0.111 5.94 5.9397 1.0 3087219 TimTec1_008285 CCCC1C(=C(N)SC(=C1C#N)N)C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I14 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3212884 TimTec1_008286 Cc1nn(CC=C)cc1Cc2cn(CC=C)nc2C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I15 compound treatment 0.278 0.0285 1.53 1.5332 1.0 3212885 TimTec1_008287 CCc1ccc(cc1)C2N(CC3CCCO3)C(=O)C(=C2C(=O)c4ccco4)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I16 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 1437719 TimTec1_008288 C=CCC(NCCc1ccccc1)c2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I17 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087220 TimTec1_008289 OC(=O)c1cc2[nH]c3CCCCc3c2cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I18 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3212886 TimTec1_008290 CC1(C)CC(CC(C)(C)N1)NCc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I19 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3211182 TimTec1_008291 O=C(NCc1ccccc1)C(C(=O)c2ccccc2)n3ccccc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I20 compound treatment 0.257 0.00753 0.4 0.4047 1.0 3087221 TimTec1_008292 Fc1ccc(CNCCN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I21 compound treatment 0.27 0.0205 1.1 1.1033 1.0 3211183 TimTec1_008293 COc1cccc(CN2CCC(CC2)C(=O)N3CCc4ccccc4C3)c1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I22 compound treatment 0.252 0.00253 0.14 0.136 1.0 1485172 TimTec1_008294 CCN(CC)CCNC1CCN(C)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I23 mock treatment 0.258 0.00853 0.46 0.4585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 I24 mock treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J01 compound treatment 0.233 -0.0165 -0.88 -0.885 -1.0 1316790 TimTec1_008295 CC1CCCC(C)N1C(=O)CCC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J02 compound treatment 0.324 0.0745 4.01 4.0052 1.0 1111854 TimTec1_008296 Cc1ccc2[nH]c(nc2c1)c3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J03 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 3211184 TimTec1_008297 OC(=O)C1CC=CCC1C(=O)NCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J04 compound treatment 0.405 0.156 8.36 8.3579 1.0 3087222 TimTec1_008298 Clc1ccc(OCCn2ccccc2=O)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J05 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3211185 TimTec1_008299 CC(C)(C)C1CC(n2nc(cc2N1)C(=O)O)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J06 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3087264 TimTec1_008300 CC1(CC2CC(C)(C)C1)CN2C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J07 compound treatment 0.263 0.0135 0.73 0.7271 1.0 1784956 TimTec1_008301 CCCCC(CC)C(=O)Nc1ccc(C#N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J08 compound treatment 0.285 0.0355 1.91 1.9094 1.0 3087265 TimTec1_008302 CCOc1cc(CO)ccc1OCC(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J09 compound treatment 0.402 0.153 8.2 8.1967 1.0 3087266 TimTec1_008303 O=C(Nc1nonc1OCCOc2nonc2NC(=O)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J10 compound treatment 0.429 0.18 9.65 9.6476 1.0 3087267 TimTec1_008304 N#Cc1cn(CCCOc2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J11 compound treatment 0.216 -0.0335 -1.8 -1.7985 -1.0 1740843 TimTec1_008305 CCOC(=O)C1=C(N)c2ccccc2CC31CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J12 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3087268 TimTec1_008306 CCOC(=O)[C@@H]1CSC(N1)c2ccc(OC)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J13 compound treatment 0.266 0.0165 0.89 0.8884 1.0 3087269 TimTec1_008307 CC(=O)Nc1nc2nc(cc(O)n2n1)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J14 compound treatment 0.487 0.238 12.76 12.7644 1.0 3211186 TimTec1_008308 CCCn1nnc(NC(=O)COc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J15 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1488887 TimTec1_008309 CC1(C)CC(=CC(C)(C)N1)c2c[nH]c(c2)C3=CC(C)(C)NC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J16 compound treatment 0.388 0.139 7.44 7.4444 1.0 3087270 TimTec1_008310 Oc1ncnc2n(Cc3ccc(F)cc3)nnc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J17 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1236834 TimTec1_008311 CC(=O)NC1CCC(C1)(C(=O)O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J18 compound treatment 0.481 0.232 12.44 12.442 1.0 1179590 TimTec1_008312 CCC(CO)NC(=O)c1cc2sc3ccccc3c2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J19 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1729523 TimTec1_008313 Cc1nc(C)c(CC=C)c(NCCO)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J20 compound treatment 0.272 0.0225 1.21 1.2108 1.0 3087271 TimTec1_008314 Cc1ccc(NCc2ccc(O)c3ncccc23)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J21 compound treatment 0.266 0.0165 0.89 0.8884 1.0 3211187 TimTec1_008315 Nc1c(C#N)sc2nc(cc(c12)C(F)(F)F)c3ccncc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J22 compound treatment 0.296 0.0465 2.5 2.5005 1.0 3087272 TimTec1_008316 O=C(CS(=O)(=O)Cc1ccccc1)Nc2nccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J23 mock treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 J24 mock treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K01 compound treatment 0.51 0.261 14.0 14.0004 1.0 3211188 TimTec1_008317 O=C(Nc1cccnc1)c2cc(on2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K02 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3211189 TimTec1_008318 COc1ccc(CN2CCC(CC2)C(=O)NC3CCCC3)cc1OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K03 compound treatment 0.253 0.00353 0.19 0.1898 1.0 1391647 TimTec1_008319 COC(=O)c1cc(no1)c2ccc(OCc3ccccc3)c(OC)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K04 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1291005 TimTec1_008320 CC(C)NC(=O)CC1Nc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K05 compound treatment 0.252 0.00253 0.14 0.136 1.0 3087273 TimTec1_008321 OC(=O)C(N1CCCCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K06 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 3211190 TimTec1_008322 Nc1ncc(c2ccccc2)n1CC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K07 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 3211191 TimTec1_008323 C(NCc1ccco1)C2CC3CC2C=C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K08 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 3087274 TimTec1_008324 CC(Sc1ccc(C)cc1)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K09 compound treatment 0.268 0.0185 1.0 0.9958 1.0 3211192 TimTec1_008325 COC(=O)C1=C(C)C(NC(=O)N1)c2ccc(OC)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K10 compound treatment 0.246 -0.00347 -0.19 -0.1864 -1.0 3087275 TimTec1_008326 CC1COC(OC1)C2C(C)CC(=CC2C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K11 compound treatment 0.398 0.149 7.98 7.9818 1.0 1256258 TimTec1_008327 O=C(CN1C(=O)c2ccccc2C1=O)Oc3ccc4ccccc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K12 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1145508 TimTec1_008328 CC(CC1OCC(CN2CCCCC2)O1)CC(C)(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K13 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1142153 TimTec1_008329 COC(=O)c1ccc(CNC(C)(C)C)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K14 compound treatment 0.255 0.00553 0.3 0.2972 1.0 1277743 TimTec1_008330 CCC1(C)CC(CCN)(CCO1)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K15 compound treatment 0.277 0.0275 1.48 1.4795 1.0 1433041 TimTec1_008331 OC(=O)c1c(sc2CCCCc12)n3cccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K16 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 1402408 TimTec1_008332 NC(Cc1ccccc1)C(O)(CC=C)CC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K17 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3211193 TimTec1_008333 Cc1ccc(C(=O)NCc2ccco2)c(C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K18 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1696859 TimTec1_008334 C(NCc1ccc2OCOc2c1)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K19 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3211194 TimTec1_008335 O=C(NC1CCCCC1)C(C(=O)c2ccccc2)n3ccccc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K20 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1125091 TimTec1_008336 CCc1ccc(CNCC2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K21 compound treatment 0.277 0.0275 1.48 1.4795 1.0 3211195 TimTec1_008337 CCN(CC)C(=O)C1CCN(Cc2ccc(Br)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K22 compound treatment 0.264 0.0145 0.78 0.7809 1.0 3087276 TimTec1_008338 CC(N1CCNCC1)c2ccc(C)c(C)c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K23 mock treatment 0.256 0.00653 0.35 0.351 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 K24 mock treatment 0.257 0.00753 0.4 0.4047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L01 compound treatment 0.232 -0.0175 -0.94 -0.9387 -1.0 1503250 TimTec1_008339 COc1ccccc1C(=O)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L02 compound treatment 0.268 0.0185 1.0 0.9958 1.0 3087277 TimTec1_008340 Clc1cccc(CNCc2ccco2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L03 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 1788809 TimTec1_008341 OC(=O)CCCC(=O)Nc1ccccc1n2ccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L04 compound treatment 0.481 0.232 12.44 12.442 1.0 3211196 TimTec1_008342 O=C(CCCOc1ccccc1)Nc2nncs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L05 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3087278 TimTec1_008343 CCc1ccc(cc1)c2nc(N)sc2CC(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L06 compound treatment 0.272 0.0225 1.21 1.2108 1.0 3211197 TimTec1_008344 CCCC(=O)N(CC)Cc1cc2cc(OC)ccc2nc1O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L07 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3087279 TimTec1_008345 FC(F)(F)C(=O)N1CCN(CC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L08 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3211198 TimTec1_008346 C(N1CCN(CC1)c2ccccn2)c3cn4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L09 compound treatment 0.385 0.136 7.28 7.2832 1.0 1481135 TimTec1_008347 COC(=O)c1ccc(Oc2cc(cc(c2)C(=O)OC)C(=O)OC)c(N)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L10 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1245186 TimTec1_008348 CC1CCCCN1C(=O)Cn2c(C)c(C#N)c3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L11 compound treatment 0.308 0.0585 3.15 3.1453 1.0 1471585 TimTec1_008349 O=S(=O)(c1nc(oc1N2CCCCC2)c3ccco3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L12 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3087280 TimTec1_008350 CN1CCC(CC1)OC(=O)c2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L13 compound treatment 0.384 0.135 7.23 7.2294 1.0 3087281 TimTec1_008351 CCc1ccc(nc1)c2ccc(C#N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L14 compound treatment 0.285 0.0355 1.91 1.9094 1.0 3211199 TimTec1_008352 CCCOc1cccc(c1)C(=O)Nc2nnn(C)n2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L15 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3087282 TimTec1_008353 CCOC(=O)c1ncn2c1C(=O)OC2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L16 compound treatment 0.281 0.0315 1.69 1.6944 1.0 3211200 TimTec1_008354 Cc1ccc(cc1)C2SC(=O)NC3=C2C(=O)c4ccccc34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L17 compound treatment 0.26 0.0105 0.57 0.5659 1.0 1784411 TimTec1_008355 CN(C)CC(O)COc1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L18 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3211201 TimTec1_008356 COC(=O)Cn1c(Cc2ccccc2)nc3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L19 compound treatment 0.321 0.0715 3.84 3.8439 1.0 3211386 TimTec1_008357 CCCc1nc2sc3CCCCc3c2c(=O)[nH]1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L20 compound treatment 0.324 0.0745 4.01 4.0052 1.0 3087283 TimTec1_008358 COc1cccc(NCc2ccc(O)c3ncccc23)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L21 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 1186739 TimTec1_008359 Nc1ccc(cc1N2CCCCC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L22 compound treatment 0.309 0.0595 3.2 3.1991 1.0 3087284 TimTec1_008360 CC1CCc2c(NCCC3CCCN3C)n4ncnc4nc2C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L23 mock treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 L24 mock treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M01 compound treatment 0.329 0.0795 4.27 4.2738 1.0 3211387 TimTec1_008361 O=C(N1CCCC1)c2cc(on2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M02 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 3211388 TimTec1_008362 COc1cccc(CN2CCC(CC2)C(=O)NC(C)C)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M03 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1578709 TimTec1_008363 CC(C)Oc1snc(Cl)c1C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M04 compound treatment 0.349 0.0995 5.35 5.3486 1.0 1479613 TimTec1_008364 CCOC(=O)c1cc(CC)sc1NC(=O)CC2Nc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M05 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 3087285 TimTec1_008365 Cc1ccc(OCC(=O)Oc2ccccn2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M06 compound treatment 0.237 -0.0125 -0.67 -0.67 -1.0 3211389 TimTec1_008366 OC(=O)C1C2OC3(CN(Cc4ccncc4)C(=O)C13)C=C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M07 compound treatment 0.367 0.118 6.32 6.3159 1.0 1127485 TimTec1_008367 OC(=O)CC1Nc2ccccc2NC1=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M08 compound treatment 0.374 0.125 6.69 6.692 1.0 1124983 TimTec1_008368 CCC(=O)N(CCC(C1CCOC(C)(C)C1)c2ccccc2)Cc3ccc(OC)cc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M09 compound treatment 0.261 0.0115 0.62 0.6197 1.0 3087286 TimTec1_008369 COC(=O)CN1C(c2ccccc2)c3cc(Br)ccc3N=C1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M10 compound treatment 0.362 0.113 6.05 6.0472 1.0 3211390 TimTec1_008370 CCn1ncc(Cc2cnn(CC)c2C)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M11 compound treatment 0.604 0.355 19.05 19.0518 1.0 3211391 TimTec1_008371 OC(=O)c1cccc(c1)c2ccc(/C=C\3/SC(=O)N(C3=O)c4ccccc4)o2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M12 compound treatment 0.33 0.0805 4.33 4.3276 1.0 3087287 TimTec1_008372 CC1=CCC2COC(C1C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M13 compound treatment 0.258 0.00853 0.46 0.4585 1.0 1012735 TimTec1_008373 CCOC(=O)c1c(C)[nH]c(C(=O)O)c1C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M14 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3211392 TimTec1_008374 Cc1ccccc1CNCc2cccnc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M15 compound treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 3087288 TimTec1_008375 CN1CCN(CC1)C(=O)Cc2ccc(F)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M16 compound treatment 0.344 0.0945 5.08 5.0799 1.0 1676992 TimTec1_008376 CNCC(O)COc1cccc(OC)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M17 compound treatment 0.461 0.212 11.37 11.3672 1.0 3211393 TimTec1_008377 O=C(NCc1ccc(cc1)c2nc3ccccc3s2)c4cccnc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M18 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 3087289 TimTec1_008378 Cc1ccc(CNCCN2CCOCC2)o1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M19 compound treatment 0.266 0.0165 0.89 0.8884 1.0 3211394 TimTec1_008379 CN(Cc1cn[nH]c1c2ccc(C)cc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M20 compound treatment 0.256 0.00653 0.35 0.351 1.0 1168279 TimTec1_008380 CN1CCC(CC1)NCc2ccccc2Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M21 compound treatment 0.26 0.0105 0.57 0.5659 1.0 3211395 TimTec1_008381 CCN(Cc1ccccc1)C(=O)C2CCN(Cc3ccc(OC)cc3)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M22 compound treatment 0.256 0.00653 0.35 0.351 1.0 3087290 TimTec1_008382 OC(=O)CCC(=O)Nc1ccc(CN2CCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M23 mock treatment 0.252 0.00253 0.14 0.136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 M24 mock treatment 0.258 0.00853 0.46 0.4585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N01 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 3211396 TimTec1_008383 CC(O)CNCc1cccc2ccccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N02 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3087291 TimTec1_008384 C(NCc1cccc2ccccc12)c3ccco3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N03 compound treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 3211397 TimTec1_008385 CC(=O)N1C(Cc2c([nH]c3ccccc23)C1(C)C)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N04 compound treatment 0.275 0.0255 1.37 1.372 1.0 3087292 TimTec1_008386 CC(C)(Oc1ccc(Cl)cc1)C(=O)N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N05 compound treatment 0.245 -0.00447 -0.24 -0.2401 -1.0 1389054 TimTec1_008387 C1CN(CCO1)c2cc(nc(n2)c3ccccc3)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N06 compound treatment 0.483 0.234 12.55 12.5495 1.0 1256237 TimTec1_008388 Nc1ccc2nc(CCCc3nc4ccc(N)cc4s3)sc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N07 compound treatment 0.422 0.173 9.27 9.2715 1.0 1651407 TimTec1_008389 CCOC(=O)c1ccc(cc1)N2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N08 compound treatment 0.359 0.11 5.89 5.886 1.0 3087340 TimTec1_008390 FC(F)(F)c1cccc(NCc2cn3ccccc3n2)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N09 compound treatment 0.303 0.0535 2.88 2.8767 1.0 1133793 TimTec1_008391 NC(=S)c1cc2cccc(CC=C)c2oc1=N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N10 compound treatment 0.302 0.0525 2.82 2.8229 1.0 3087341 TimTec1_008392 Oc1ccc(CNc2cccc(Cl)c2)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N11 compound treatment 0.288 0.0385 2.07 2.0706 1.0 1331799 TimTec1_008393 O=C(N1CCCn2c1nc3ccccc23)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N12 compound treatment 0.26 0.0105 0.57 0.5659 1.0 3087342 TimTec1_008394 COc1ccc(cc1)C(=O)OC(C)CN2CCN(C)CC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N13 compound treatment 0.239 -0.0105 -0.56 -0.5626 -1.0 1365632 TimTec1_008395 OC1=C(C(C2=C(O)CCCC2=O)c3ccccc3)C(=O)CCC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N14 compound treatment 0.314 0.0645 3.47 3.4678 1.0 3211398 TimTec1_008396 CCCC(=O)Nc1ccc2oc(=O)ccc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N15 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 1175335 TimTec1_008397 OC1(C#CCN2CCCCC2)C3CCCC3c4ccccc41 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N16 compound treatment 0.544 0.295 15.83 15.8275 1.0 1871509 TimTec1_008398 CCNc1nnc(s1)c2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N17 compound treatment 0.294 0.0445 2.39 2.393 1.0 1297935 TimTec1_008399 CSc1nc(C)c(CC=C)c(Nc2ccccc2)n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N18 compound treatment 0.402 0.153 8.2 8.1967 1.0 3087343 TimTec1_008400 Clc1ccc(OCC(=O)n2cnnc2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N19 compound treatment 0.263 0.0135 0.73 0.7271 1.0 1787965 TimTec1_008401 COc1cc(ccc1OCc2ccccc2)c3cc(C#N)on3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N20 compound treatment 0.348 0.0985 5.29 5.2949 1.0 3087344 TimTec1_008402 COc1ccc(cc1OC)C(=O)OCC(=O)Nc2sc3CCCc3c2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N21 compound treatment 0.352 0.103 5.51 5.5098 1.0 3211399 TimTec1_008403 CC(C)N1CCCc2cc(CN)ccc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N22 compound treatment 0.376 0.127 6.8 6.7995 1.0 1235712 TimTec1_008404 CC1=C(C(c2ccco2)c3c(N)c(C#N)sc3N1)C(=O)OCC=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N23 mock treatment 0.251 0.00153 0.08 0.0823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 N24 mock treatment 0.241 -0.00847 -0.46 -0.4551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O01 compound treatment 0.267 0.0175 0.94 0.9421 1.0 3087345 TimTec1_008405 CCc1c(C)sc(NC(=O)c2cc(on2)c3ccccc3)c1C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O02 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3211400 TimTec1_008406 CCOC(=O)C1CCN(CC1)C(=O)C(C(=O)c2ccccc2)n3ccccc3=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O03 compound treatment 0.254 0.00453 0.24 0.2435 1.0 1120969 TimTec1_008407 OCC(NCc1ccccc1)C#CCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O04 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3211401 TimTec1_008408 Clc1c(sc2ccccc12)C(=O)N(CC#N)CC#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O05 compound treatment 0.275 0.0255 1.37 1.372 1.0 3087346 TimTec1_008409 Cc1cccc(c1)C(=O)OCCN2CCOCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O06 compound treatment 0.287 0.0375 2.02 2.0169 1.0 1523381 TimTec1_008410 NCCc1c([nH]c2ccc(Br)cc12)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O07 compound treatment 0.259 0.00953 0.51 0.5122 1.0 3087347 TimTec1_008411 CC1CCCC(C)N1Cc2ccc(N)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O08 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 1667083 TimTec1_008412 CCOC(=O)CC1(O)CCOC(C)(C)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O09 compound treatment 0.256 0.00653 0.35 0.351 1.0 1350048 TimTec1_008413 OC(=O)CCCC(=O)Nc1nccs1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O10 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 3087348 TimTec1_008414 CC1=CCC(CC1)C2OCC3CC=C(C)C2C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O11 compound treatment 0.266 0.0165 0.89 0.8884 1.0 1227036 TimTec1_008415 C(NCc1ccco1)C2OCc3ccccc3CO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O12 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3211402 TimTec1_008416 COc1ccc(cc1)C(CCNCc2ccccc2)C3CCOC(C)(C)C3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O13 compound treatment 0.257 0.00753 0.4 0.4047 1.0 1661425 TimTec1_008417 CCc1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O14 compound treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1171536 TimTec1_008418 CC(C)(C)c1ccc(CNCc2ccco2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O15 compound treatment 0.272 0.0225 1.21 1.2108 1.0 3211403 TimTec1_008419 Cc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3ccccn3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O16 compound treatment 0.25 5.31E-4 0.03 0.0285 1.0 1064846 TimTec1_008420 COc1ccccc1CNCc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O17 compound treatment 0.276 0.0265 1.43 1.4257 1.0 3211404 TimTec1_008421 CCN(CC)C(=O)C(C(=O)c1ccccc1)n2cc(Cl)ccc2=O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O18 compound treatment 0.252 0.00253 0.14 0.136 1.0 3087349 TimTec1_008422 CCOc1ccccc1CNC2CC(C)(C)NC(C)(C)C2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O19 compound treatment 0.276 0.0265 1.43 1.4257 1.0 3211482 TimTec1_008423 OCCN(Cc1cn[nH]c1c2ccc(F)cc2)Cc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O20 compound treatment 0.251 0.00153 0.08 0.0823 1.0 3087350 TimTec1_008424 NCC(N1CCOCC1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O21 compound treatment 0.253 0.00353 0.19 0.1898 1.0 3211483 TimTec1_008425 COc1ccc(CN2CCC(CC2)C(=O)NCc3ccc(C)cc3)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O22 compound treatment 0.254 0.00453 0.24 0.2435 1.0 3087351 TimTec1_008426 CC(C)C1NC(Cc2c1[nH]c3ccccc23)C(=O)O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O23 mock treatment 0.265 0.0155 0.83 0.8346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 O24 mock treatment 0.247 -0.00247 -0.13 -0.1327 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P01 compound treatment 0.234 -0.0155 -0.83 -0.8313 -1.0 3211484 TimTec1_008427 CN1CCN(CC1)C(=O)C2CCC(C)(C(=O)O)C2(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P02 compound treatment 0.416 0.167 8.95 8.949 1.0 1580692 TimTec1_008428 Fc1ccc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)NCC=C)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P03 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 3087352 TimTec1_008429 Nc1ccc(CN2CCCCCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P04 compound treatment 0.505 0.256 13.73 13.7317 1.0 3087353 TimTec1_008430 Cc1cc(OCC(=O)Nc2nnn(C)n2)ccc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P05 compound treatment 0.236 -0.0135 -0.72 -0.7238 -1.0 1521332 TimTec1_008431 CC(C)C1CC(CCN)(Cc2ccccc2)CCO1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P06 compound treatment 0.431 0.182 9.76 9.7551 1.0 3087354 TimTec1_008432 Cc1ccc(CC2SC(=O)NC2=O)cc1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P07 compound treatment 0.337 0.0875 4.7 4.7037 1.0 1530249 TimTec1_008433 Oc1ccnc2cccc(Cc3ccccc3)c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P08 compound treatment 0.428 0.179 9.59 9.5939 1.0 1360748 TimTec1_008434 Cc1nc2sccn2c1c3csc(NCc4ccco4)n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P09 compound treatment 0.24 -0.00947 -0.51 -0.5088 -1.0 1231944 TimTec1_008435 CCOC(=O)C1C(C(C1c2ccccc2)C(=O)OCC)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P10 compound treatment 0.265 0.0155 0.83 0.8346 1.0 3211485 TimTec1_008436 Oc1ccc(CNc2ccc(F)cc2)c3cccnc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P11 compound treatment 0.257 0.00753 0.4 0.4047 1.0 1543749 TimTec1_008437 Cc1ccccc1OCC2Cn3c(O2)nc4n(C)c(=O)[nH]c(=O)c34 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P12 compound treatment 0.242 -0.00747 -0.4 -0.4014 -1.0 3087355 TimTec1_008438 CN1CCC(CC1)OC(=O)COc2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P13 compound treatment 0.319 0.0695 3.74 3.7365 1.0 1684258 TimTec1_008439 Cc1c(C)c2cc(ccc2n1Cc3ccccc3)C(=O)Nc4nc[nH]n4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P14 compound treatment 0.447 0.198 10.61 10.6149 1.0 3087356 TimTec1_008440 O=C(COc1ccccc1)Nc2ccc3oc(=O)ccc3c2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P15 compound treatment 0.23 -0.0195 -1.05 -1.0462 -1.0 1396380 TimTec1_008441 CCC(CO)NC(=O)c1ccc(N)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P16 compound treatment 0.248 -0.00147 -0.08 -0.0789 -1.0 3087357 TimTec1_008442 COc1ccc(cc1)n2cccc2CO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P17 compound treatment 0.252 0.00253 0.14 0.136 1.0 1269164 TimTec1_008443 CCN1CCN(CCC(=O)Nc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P18 compound treatment 0.408 0.159 8.52 8.5191 1.0 1595939 TimTec1_008444 COc1ccc(cc1)c2nn(CCC#N)cc2C#N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P19 compound treatment 0.238 -0.0115 -0.62 -0.6163 -1.0 1426447 TimTec1_008445 O=C(NCCN1CCOCC1)c2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P20 compound treatment 0.235 -0.0145 -0.78 -0.7775 -1.0 3087358 TimTec1_008446 CCc1cccc2c(O)c(CN(C)C)c(C)nc12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P21 compound treatment 0.224 -0.0255 -1.37 -1.3686 -1.0 1501786 TimTec1_008447 Nc1cc(Cl)ccc1N2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P22 compound treatment 0.244 -0.00547 -0.29 -0.2939 -1.0 1517444 TimTec1_008448 CCOC(=O)C1=C(C)NC(=O)C(C(=O)N)C21CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P23 mock treatment 0.249 -4.69E-4 -0.03 -0.0252 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2086 P24 mock treatment 0.253 0.00353 0.19 0.1898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A01 compound treatment 0.291 0.0476 2.56 2.5562 1.0 1077351 TimTec1_008449 COC(=O)c1cncn1C(C)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A02 mock treatment 0.21 -0.0334 -1.8 -1.7966 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A03 compound treatment 0.459 0.216 11.58 11.5842 1.0 3211486 TimTec1_008450 CC(=O)N1CCN(CC1)c2ccc(NC(=O)COc3cc(C)c(Cl)c(C)c3)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A04 mock treatment 0.226 -0.0174 -0.94 -0.9368 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A05 compound treatment 0.351 0.108 5.78 5.7805 1.0 3087359 TimTec1_008451 O=c1sc2ccccc2n1CCOc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A06 mock treatment 0.228 -0.0154 -0.83 -0.8293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A07 compound treatment 0.233 -0.0104 -0.56 -0.5606 -1.0 3087360 TimTec1_008452 CCCN1CCC(CC1)NCc2ccco2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A08 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A09 compound treatment 0.265 0.0216 1.16 1.159 1.0 3211487 TimTec1_008453 CC(C)(C)C(=O)COC(=O)C1CN(C(=O)C1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A10 mock treatment 0.229 -0.0144 -0.78 -0.7756 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A11 compound treatment 0.261 0.0176 0.94 0.9441 1.0 3087361 TimTec1_008454 Cc1ccc(cc1)c2ccc(C(=O)O)n2C=C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A12 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A13 compound treatment 0.246 0.00257 0.14 0.138 1.0 1686575 TimTec1_008455 CCN(CC)CCC(=O)c1ccc(F)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A14 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A15 compound treatment 0.369 0.126 6.75 6.7477 1.0 3211488 TimTec1_008456 O=C(CSc1ccccn1)N2CCN(CC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A16 mock treatment 0.234 -0.00943 -0.51 -0.5069 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A17 compound treatment 0.341 0.0976 5.24 5.2431 1.0 3087362 TimTec1_008457 Clc1ncn(CCOc2ccccc2)c1Cl 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A18 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A19 mock treatment 0.317 0.0736 3.95 3.9534 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A20 mock treatment 0.232 -0.0114 -0.61 -0.6143 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A21 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A22 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A23 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 A24 mock treatment 0.261 0.0176 0.94 0.9441 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B01 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B02 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B03 mock treatment 0.257 0.0136 0.73 0.7291 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B04 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B05 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B06 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B07 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B08 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B09 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B10 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B11 mock treatment 0.253 0.00957 0.51 0.5142 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B12 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B13 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B14 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B15 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B16 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B17 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B18 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B19 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B20 mock treatment 0.233 -0.0104 -0.56 -0.5606 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B21 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B22 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B23 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 B24 mock treatment 0.225 -0.0184 -0.99 -0.9905 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C01 compound treatment 0.244 5.68E-4 0.03 0.0305 1.0 3211489 TimTec1_008458 OC(c1ccc([nH]1)c2ccccc2)C(F)(F)F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C02 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C03 compound treatment 0.254 0.0106 0.57 0.5679 1.0 3087363 TimTec1_008459 NCCCn1c2CCCCc2c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C04 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C05 compound treatment 0.279 0.0356 1.91 1.9113 1.0 3211490 TimTec1_008460 Cc1cc(C)c(C#N)c(n1)N2C3CCC2CC(O)(C3)c4ccc(F)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C06 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C07 compound treatment 0.25 0.00657 0.35 0.3529 1.0 3087364 TimTec1_008461 Cc1ccccc1CN2CCC(CC2)N3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C08 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C09 compound treatment 0.293 0.0496 2.66 2.6637 1.0 3211491 TimTec1_008462 FC(F)(F)c1ccc(NCc2cn3ccccc3n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C10 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C11 compound treatment 0.286 0.0426 2.29 2.2875 1.0 1349387 TimTec1_008463 COc1ccc2n(C)c(C)c(c3csc(N)n3)c2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C12 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C13 compound treatment 0.29 0.0466 2.5 2.5025 1.0 3211492 TimTec1_008464 Oc1ccc(cc1)C(=O)OCCCN2CCCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C14 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C15 compound treatment 0.337 0.0936 5.03 5.0281 1.0 3211493 TimTec1_008465 COc1cccc(Cn2c(nc3ccccc23)c4cncs4)c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C16 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C17 compound treatment 0.355 0.112 6.0 5.9954 1.0 3087365 TimTec1_008466 Cc1ccccc1OCCCn2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C18 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C19 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C20 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C21 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C22 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C23 mock treatment 0.261 0.0176 0.94 0.9441 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 C24 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D01 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D02 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D03 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D04 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D05 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D06 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D07 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D08 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D09 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D10 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D11 mock treatment 0.232 -0.0114 -0.61 -0.6143 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D12 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D13 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D14 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D15 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D16 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D17 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D18 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D19 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D20 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D21 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D22 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D23 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 D24 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E01 compound treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1720370 TimTec1_008467 C1CCC(CC1)Nc2nnnn2c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E02 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E03 compound treatment 0.254 0.0106 0.57 0.5679 1.0 3087366 TimTec1_008468 CCC(=O)Nc1ccc(cc1)N2CCN(CC2)C(=O)C(C)C 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E04 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E05 compound treatment 0.474 0.231 12.39 12.3902 1.0 3211494 TimTec1_008469 Oc1nc2nonc2nc1Nc3ccccc3F 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E06 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E07 compound treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 3087367 TimTec1_008470 Clc1cccc(c1)C(=O)N2CCNCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E08 mock treatment 0.256 0.0126 0.68 0.6754 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E09 compound treatment 0.27 0.0266 1.43 1.4277 1.0 3211495 TimTec1_008471 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E10 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E11 compound treatment 0.296 0.0526 2.82 2.8249 1.0 1406058 TimTec1_008472 OC(=O)CCNc1nc2ccccc2s1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E12 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E13 compound treatment 0.314 0.0706 3.79 3.7922 1.0 1411493 TimTec1_008473 CC(C)(C)c1cn2c(nc3ccccc32)n1CCCO 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E14 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E15 compound treatment 0.258 0.0146 0.78 0.7828 1.0 1197110 TimTec1_008474 OC1(CCCCC1)C#CCN2CCN(CC2)C(=O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E16 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E17 compound treatment 0.498 0.255 13.68 13.6799 1.0 3087413 TimTec1_008475 COc1nc(N)c(C#N)c(c1C#N)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E18 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E19 mock treatment 0.256 0.0126 0.68 0.6754 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E20 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E21 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E22 mock treatment 0.262 0.0186 1.0 0.9978 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E23 mock treatment 0.257 0.0136 0.73 0.7291 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 E24 mock treatment 0.262 0.0186 1.0 0.9978 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F01 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F02 mock treatment 0.252 0.00857 0.46 0.4604 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F03 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F04 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F05 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F06 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F07 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F08 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F09 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F10 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F11 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F12 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F13 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F14 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F15 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F16 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F17 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F18 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F19 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F20 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F21 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F22 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F23 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 F24 mock treatment 0.225 -0.0184 -0.99 -0.9905 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G01 compound treatment 0.381 0.138 7.39 7.3926 1.0 1325717 TimTec1_008476 OC(COc1ccccc1)Cn2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G02 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G03 compound treatment 0.294 0.0506 2.72 2.7174 1.0 1168629 TimTec1_008477 Nc1nonc1C(=O)OCC(=O)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G04 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G05 compound treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1787057 TimTec1_008478 CC(=O)OC1CN2CCC1C(C2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G06 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G07 compound treatment 0.273 0.0296 1.59 1.5889 1.0 3087414 TimTec1_008479 CN1CCCC(C1)OC(=O)COc2ccc(C)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G08 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G09 compound treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1134052 TimTec1_008480 CC(C)(C)N1CC(CO)OC1c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G10 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G11 compound treatment 0.247 0.00357 0.19 0.1917 1.0 3087415 TimTec1_008481 CCN1CCN(Cc2ccc(N)cc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G12 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G13 compound treatment 0.257 0.0136 0.73 0.7291 1.0 1650768 TimTec1_008482 O=C(Nc1ccncc1)C2(CCCC2)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G14 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G15 compound treatment 0.272 0.0286 1.54 1.5352 1.0 3211571 TimTec1_008483 Cc1ccc(cc1C)c2[nH]ncc2CNCc3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G16 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G17 compound treatment 0.272 0.0286 1.54 1.5352 1.0 3087416 TimTec1_008484 COC(=O)c1cc([nH]n1)c2ccccc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G18 mock treatment 0.253 0.00957 0.51 0.5142 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G19 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G20 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G21 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G22 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G23 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 G24 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H01 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H02 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H03 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H04 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H05 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H06 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H07 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H08 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H09 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H10 mock treatment 0.233 -0.0104 -0.56 -0.5606 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H11 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H12 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H13 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H14 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H15 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H16 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H17 mock treatment 0.253 0.00957 0.51 0.5142 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H18 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H19 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H20 mock treatment 0.227 -0.0164 -0.88 -0.883 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H21 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H22 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H23 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 H24 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I01 compound treatment 0.472 0.229 12.28 12.2828 1.0 3211572 TimTec1_008485 CC(=O)OC(COc1ccccc1)Cn2cnc3ccccc23 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I02 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I03 compound treatment 0.355 0.112 6.0 5.9954 1.0 3087417 TimTec1_008486 COc1ccc(cc1Br)C(=O)COC(=O)CCc2nc3ccccc3nc2O 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I04 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I05 compound treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 3211573 TimTec1_008487 Cc1ccc(cc1)C(=O)NCCN2CCCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I06 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I07 compound treatment 0.422 0.179 9.6 9.5959 1.0 3211574 TimTec1_008488 Cc1ccc(OCCCC(=O)Nc2nccs2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I08 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I09 compound treatment 0.244 5.68E-4 0.03 0.0305 1.0 3087418 TimTec1_008489 N#CC1CCN(Cc2ccccc2)CC1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I10 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I11 compound treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1290823 TimTec1_008490 CC(C)C(=O)N1C(C)CC(N(C(=O)C)c2ccccc2)c3ccccc13 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I12 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I13 compound treatment 0.269 0.0256 1.37 1.374 1.0 3087419 TimTec1_008491 CCCOc1ccc(Cc2nc(N)c(NC(=O)C)c(O)n2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I14 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I15 compound treatment 0.406 0.163 8.74 8.7361 1.0 1691184 TimTec1_008492 O=c1oc2ccccc2cc1c3cn4ccccc4n3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I16 mock treatment 0.253 0.00957 0.51 0.5142 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I17 compound treatment 0.48 0.237 12.71 12.7127 1.0 1132623 TimTec1_008493 Cn1c2nc(c(CCC(=O)O)n2c3ccccc13)c4ccccc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I18 mock treatment 0.259 0.0156 0.84 0.8366 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I19 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I20 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I21 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I22 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I23 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 I24 mock treatment 0.256 0.0126 0.68 0.6754 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J01 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J02 mock treatment 0.234 -0.00943 -0.51 -0.5069 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J03 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J04 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J05 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J06 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J07 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J08 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J09 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J10 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J11 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J12 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J13 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J14 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J15 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J16 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J17 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J18 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J19 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J20 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J21 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J22 mock treatment 0.234 -0.00943 -0.51 -0.5069 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J23 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 J24 mock treatment 0.253 0.00957 0.51 0.5142 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K01 compound treatment 0.257 0.0136 0.73 0.7291 1.0 1586834 TimTec1_008494 Cc1c(C#N)c2ccccc2n1CC(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K02 mock treatment 0.252 0.00857 0.46 0.4604 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K03 compound treatment 0.255 0.0116 0.62 0.6216 1.0 3211575 TimTec1_008495 CC(C)(Oc1ccc(Cl)cc1)C(=O)NCC2CCCO2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K04 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K05 compound treatment 0.266 0.0226 1.21 1.2127 1.0 3087420 TimTec1_008496 NC(=O)c1ccc(CN2CCOCC2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K06 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K07 compound treatment 0.463 0.22 11.8 11.7991 1.0 1260773 TimTec1_008497 Nc1c(c2nc3ccccc3s2)c4nc(C#N)c(C#N)nc4n1CC5CCCO5 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K08 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K09 compound treatment 0.334 0.0906 4.87 4.8669 1.0 3087421 TimTec1_008498 CC1CCCN(C1)C(=O)Cc2cccs2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K10 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K11 compound treatment 0.299 0.0556 2.99 2.9861 1.0 3211576 TimTec1_008499 CC1(C)CC(=O)C=C(C1)Nc2sc3CCCCc3c2C(=O)N 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K12 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K13 compound treatment 0.499 0.256 13.73 13.7337 1.0 3087422 TimTec1_008500 Cn1c(nc2cc(N)ccc12)c3ccc4nc(N)sc4c3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K14 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K15 compound treatment 0.342 0.0986 5.3 5.2968 1.0 1350314 TimTec1_008501 CC(C)NCCn1c(cn2c1nc3ccccc32)c4ccc(Br)cc4 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K16 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K17 mock treatment 0.263 0.0196 1.05 1.0515 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K18 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K19 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K20 mock treatment 0.25 0.00657 0.35 0.3529 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K21 mock treatment 0.253 0.00957 0.51 0.5142 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K22 mock treatment 0.268 0.0246 1.32 1.3202 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K23 mock treatment 0.258 0.0146 0.78 0.7828 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 K24 mock treatment 0.264 0.0206 1.11 1.1053 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L01 mock treatment 0.233 -0.0104 -0.56 -0.5606 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L02 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L03 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L04 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L05 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L06 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L07 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L08 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L09 mock treatment 0.252 0.00857 0.46 0.4604 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L10 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L11 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L12 mock treatment 0.244 5.68E-4 0.03 0.0305 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L13 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L14 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L15 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L16 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L17 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L18 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L19 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L20 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L21 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L22 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L23 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 L24 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M01 compound treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1597861 TimTec1_008502 O=S1(=O)CC(NCc2ccccc2)C=C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M02 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M03 compound treatment 0.257 0.0136 0.73 0.7291 1.0 1709566 TimTec1_008503 Fc1ccc(NC(=O)C2CCCO2)cc1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M04 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M05 compound treatment 0.561 0.318 17.07 17.0654 1.0 3211577 TimTec1_008504 CC(C)NC(=O)C1COc2ccccc2O1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M06 mock treatment 0.234 -0.00943 -0.51 -0.5069 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M07 compound treatment 0.303 0.0596 3.2 3.201 1.0 1778660 TimTec1_008505 COC(=O)c1c(Cl)n2cnccc2c1C(=O)OC 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M08 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M09 compound treatment 0.255 0.0116 0.62 0.6216 1.0 3211578 TimTec1_008506 CCCc1noc2CC(C)(C)C/C(=N/O)/c12 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M10 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M11 compound treatment 0.247 0.00357 0.19 0.1917 1.0 1923180 TimTec1_008507 CC1(C)CC(=O)C(=CNCCN2CCNCC2)C(=O)C1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M12 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M13 compound treatment 0.378 0.135 7.23 7.2314 1.0 3087423 TimTec1_008508 C(Nc1ncn[nH]1)c2ccc(NCc3cccc4ccccc34)cc2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M14 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M15 compound treatment 0.251 0.00757 0.41 0.4067 1.0 3211579 TimTec1_008509 OC(=O)C1=CC2c3ccccc3C1c4ccccc24 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M16 mock treatment 0.262 0.0186 1.0 0.9978 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M17 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M18 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M19 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M20 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M21 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M22 mock treatment 0.248 0.00457 0.25 0.2455 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M23 mock treatment 0.258 0.0146 0.78 0.7828 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 M24 mock treatment 0.269 0.0256 1.37 1.374 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N01 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N02 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N03 mock treatment 0.256 0.0126 0.68 0.6754 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N04 mock treatment 0.257 0.0136 0.73 0.7291 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N05 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N06 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N07 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N08 mock treatment 0.252 0.00857 0.46 0.4604 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N09 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N10 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N11 mock treatment 0.236 -0.00743 -0.4 -0.3994 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N12 mock treatment 0.233 -0.0104 -0.56 -0.5606 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N13 mock treatment 0.239 -0.00443 -0.24 -0.2382 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N14 mock treatment 0.233 -0.0104 -0.56 -0.5606 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N15 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N16 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N17 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N18 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N19 mock treatment 0.237 -0.00643 -0.35 -0.3457 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N20 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N21 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N22 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N23 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 N24 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O01 compound treatment 0.302 0.0586 3.15 3.1473 1.0 3211580 TimTec1_008510 Nc1nc2ccc(cc2s1)C(=O)OC3CCCCC3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O02 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O03 compound treatment 0.416 0.173 9.27 9.2734 1.0 1790435 TimTec1_008511 Cc1cc(C(=O)OCC(=O)Nc2sc3CCCCc3c2C#N)c4ccccc4n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O04 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O05 compound treatment 0.257 0.0136 0.73 0.7291 1.0 3211581 TimTec1_008512 CN1C2=C(C(C3=C1CCCC3=O)c4ccccc4)C(=O)CCC2 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O06 mock treatment 0.247 0.00357 0.19 0.1917 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O07 compound treatment 0.263 0.0196 1.05 1.0515 1.0 1677589 TimTec1_008513 O=C(Cc1cccc2ccccc12)NCC3CCCO3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O08 mock treatment 0.26 0.0166 0.89 0.8903 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O09 compound treatment 0.276 0.0326 1.75 1.7501 1.0 1210690 TimTec1_008514 COC(=O)CCNc1ccc2OCCOc2c1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O10 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O11 compound treatment 0.311 0.0676 3.63 3.6309 1.0 1483611 TimTec1_008515 CCOC(=O)c1cnc2cc(nn2c1O)c3ccccc3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O12 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O13 compound treatment 0.306 0.0626 3.36 3.3623 1.0 3087424 TimTec1_008516 O=C(CC(c1ccccc1)c2ccccc2)Nc3nnc[nH]3 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O14 mock treatment 0.229 -0.0144 -0.78 -0.7756 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O15 compound treatment 0.271 0.0276 1.48 1.4814 1.0 3211582 TimTec1_008517 Cc1cc(NCc2ccccc2)n3ncnc3n1 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O16 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O17 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O18 mock treatment 0.259 0.0156 0.84 0.8366 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O19 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O20 mock treatment 0.252 0.00857 0.46 0.4604 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O21 mock treatment 0.24 -0.00343 -0.18 -0.1844 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O22 mock treatment 0.259 0.0156 0.84 0.8366 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O23 mock treatment 0.249 0.00557 0.3 0.2992 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 O24 mock treatment 0.257 0.0136 0.73 0.7291 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P01 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P02 mock treatment 0.276 0.0326 1.75 1.7501 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P03 mock treatment 0.262 0.0186 1.0 0.9978 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P04 mock treatment 0.267 0.0236 1.27 1.2665 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P05 mock treatment 0.254 0.0106 0.57 0.5679 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P06 mock treatment 0.257 0.0136 0.73 0.7291 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P07 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P08 mock treatment 0.251 0.00757 0.41 0.4067 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P09 mock treatment 0.243 -4.32E-4 -0.02 -0.0232 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P10 mock treatment 0.241 -0.00243 -0.13 -0.1307 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P11 mock treatment 0.242 -0.00143 -0.08 -0.077 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P12 mock treatment 0.235 -0.00843 -0.45 -0.4531 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P13 mock treatment 0.272 0.0286 1.54 1.5352 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P14 mock treatment 0.217 -0.0264 -1.42 -1.4204 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P15 mock treatment 0.218 -0.0254 -1.37 -1.3667 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P16 mock treatment 0.231 -0.0124 -0.67 -0.6681 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P17 mock treatment 0.219 -0.0244 -1.31 -1.3129 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P18 mock treatment 0.213 -0.0304 -1.64 -1.6354 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P19 mock treatment 0.221 -0.0224 -1.21 -1.2055 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P20 mock treatment 0.23 -0.0134 -0.72 -0.7218 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P21 mock treatment 0.245 0.00157 0.08 0.0842 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P22 mock treatment 0.228 -0.0154 -0.83 -0.8293 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P23 mock treatment 0.238 -0.00543 -0.29 -0.2919 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.2087 P24 mock treatment 0.246 0.00257 0.14 0.138 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A01 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A02 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A03 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A04 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A05 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A06 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A07 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A08 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A09 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A10 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A11 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A12 mock treatment 0.216 -0.00775 -0.42 -0.4163 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A13 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A14 mock treatment 0.205 -0.0187 -1.01 -1.0074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A15 mock treatment 0.209 -0.0147 -0.79 -0.7924 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A16 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A17 mock treatment 0.205 -0.0187 -1.01 -1.0074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A18 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A19 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A20 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A21 mock treatment 0.202 -0.0217 -1.17 -1.1686 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A22 mock treatment 0.203 -0.0207 -1.11 -1.1149 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A23 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base A24 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B01 mock treatment 0.237 0.0133 0.71 0.7122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B02 mock treatment 0.267 0.0433 2.32 2.3244 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B03 mock treatment 0.245 0.0213 1.14 1.1421 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B04 mock treatment 0.26 0.0363 1.95 1.9482 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B05 mock treatment 0.262 0.0383 2.06 2.0557 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B06 mock treatment 0.252 0.0283 1.52 1.5183 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B07 mock treatment 0.259 0.0353 1.89 1.8945 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B08 mock treatment 0.257 0.0333 1.79 1.787 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B09 mock treatment 0.242 0.0183 0.98 0.9809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B10 mock treatment 0.249 0.0253 1.36 1.3571 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B11 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B12 mock treatment 0.243 0.0193 1.03 1.0346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B13 mock treatment 0.231 0.00725 0.39 0.3898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B14 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B15 mock treatment 0.241 0.0173 0.93 0.9272 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B16 mock treatment 0.241 0.0173 0.93 0.9272 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B17 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B18 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B19 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B20 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B21 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B22 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B23 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base B24 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C01 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C02 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C03 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C04 mock treatment 0.243 0.0193 1.03 1.0346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C05 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C06 mock treatment 0.245 0.0213 1.14 1.1421 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C07 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C08 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C09 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C10 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C11 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C12 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C13 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C14 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C15 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C16 mock treatment 0.217 -0.00675 -0.36 -0.3625 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C17 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C18 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C19 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C20 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C21 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C22 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C23 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base C24 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D01 mock treatment 0.25 0.0263 1.41 1.4108 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D02 mock treatment 0.258 0.0343 1.84 1.8407 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D03 mock treatment 0.249 0.0253 1.36 1.3571 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D04 mock treatment 0.245 0.0213 1.14 1.1421 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D05 mock treatment 0.245 0.0213 1.14 1.1421 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D06 mock treatment 0.249 0.0253 1.36 1.3571 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D07 mock treatment 0.247 0.0233 1.25 1.2496 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D08 mock treatment 0.237 0.0133 0.71 0.7122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D09 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D10 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D11 mock treatment 0.237 0.0133 0.71 0.7122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D12 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D13 mock treatment 0.231 0.00725 0.39 0.3898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D14 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D15 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D16 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D17 mock treatment 0.217 -0.00675 -0.36 -0.3625 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D18 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D19 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D20 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D21 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D22 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D23 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base D24 mock treatment 0.216 -0.00775 -0.42 -0.4163 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E01 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E02 mock treatment 0.237 0.0133 0.71 0.7122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E03 mock treatment 0.243 0.0193 1.03 1.0346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E04 mock treatment 0.238 0.0143 0.77 0.766 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E05 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E06 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E07 mock treatment 0.234 0.0103 0.55 0.551 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E08 mock treatment 0.234 0.0103 0.55 0.551 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E09 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E10 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E11 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E12 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E13 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E14 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E15 mock treatment 0.213 -0.0107 -0.58 -0.5775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E16 mock treatment 0.217 -0.00675 -0.36 -0.3625 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E17 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E18 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E19 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E20 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E21 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E22 mock treatment 0.231 0.00725 0.39 0.3898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E23 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base E24 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F01 mock treatment 0.252 0.0283 1.52 1.5183 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F02 mock treatment 0.258 0.0343 1.84 1.8407 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F03 mock treatment 0.255 0.0313 1.68 1.6795 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F04 mock treatment 0.255 0.0313 1.68 1.6795 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F05 mock treatment 0.249 0.0253 1.36 1.3571 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F06 mock treatment 0.241 0.0173 0.93 0.9272 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F07 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F08 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F09 mock treatment 0.251 0.0273 1.46 1.4646 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F10 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F11 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F12 mock treatment 0.242 0.0183 0.98 0.9809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F13 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F14 mock treatment 0.217 -0.00675 -0.36 -0.3625 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F15 mock treatment 0.234 0.0103 0.55 0.551 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F16 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F17 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F18 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F19 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F20 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F21 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F22 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F23 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base F24 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G01 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G02 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G03 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G04 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G05 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G06 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G07 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G08 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G09 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G10 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G11 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G12 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G13 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G14 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G15 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G16 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G17 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G18 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G19 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G20 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G21 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G22 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G23 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base G24 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H01 mock treatment 0.245 0.0213 1.14 1.1421 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H02 mock treatment 0.254 0.0303 1.63 1.6258 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H03 mock treatment 0.257 0.0333 1.79 1.787 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H04 mock treatment 0.244 0.0203 1.09 1.0884 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H05 mock treatment 0.248 0.0243 1.3 1.3033 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H06 mock treatment 0.248 0.0243 1.3 1.3033 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H07 mock treatment 0.248 0.0243 1.3 1.3033 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H08 mock treatment 0.255 0.0313 1.68 1.6795 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H09 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H10 mock treatment 0.246 0.0223 1.2 1.1959 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H11 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H12 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H13 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H14 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H15 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H16 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H17 mock treatment 0.248 0.0243 1.3 1.3033 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H18 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H19 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H20 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H21 mock treatment 0.217 -0.00675 -0.36 -0.3625 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H22 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H23 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base H24 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I01 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I02 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I03 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I04 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I05 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I06 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I07 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I08 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I09 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I10 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I11 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I12 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I13 mock treatment 0.204 -0.0197 -1.06 -1.0611 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I14 mock treatment 0.213 -0.0107 -0.58 -0.5775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I15 mock treatment 0.211 -0.0127 -0.68 -0.685 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I16 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I17 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I18 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I19 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I20 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I21 mock treatment 0.213 -0.0107 -0.58 -0.5775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I22 mock treatment 0.195 -0.0287 -1.54 -1.5448 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I23 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base I24 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J01 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J02 mock treatment 0.25 0.0263 1.41 1.4108 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J03 mock treatment 0.261 0.0373 2.0 2.0019 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J04 mock treatment 0.256 0.0323 1.73 1.7332 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J05 mock treatment 0.253 0.0293 1.57 1.572 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J06 mock treatment 0.247 0.0233 1.25 1.2496 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J07 mock treatment 0.25 0.0263 1.41 1.4108 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J08 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J09 mock treatment 0.242 0.0183 0.98 0.9809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J10 mock treatment 0.253 0.0293 1.57 1.572 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J11 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J12 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J13 mock treatment 0.231 0.00725 0.39 0.3898 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J14 mock treatment 0.237 0.0133 0.71 0.7122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J15 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J16 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J17 mock treatment 0.234 0.0103 0.55 0.551 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J18 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J19 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J20 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J21 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J22 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J23 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base J24 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K01 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K02 mock treatment 0.244 0.0203 1.09 1.0884 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K03 mock treatment 0.237 0.0133 0.71 0.7122 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K04 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K05 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K06 mock treatment 0.238 0.0143 0.77 0.766 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K07 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K08 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K09 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K10 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K11 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K12 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K13 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K14 mock treatment 0.203 -0.0207 -1.11 -1.1149 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K15 mock treatment 0.203 -0.0207 -1.11 -1.1149 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K16 mock treatment 0.209 -0.0147 -0.79 -0.7924 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K17 mock treatment 0.199 -0.0247 -1.33 -1.3298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K18 mock treatment 0.208 -0.0157 -0.85 -0.8462 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K19 mock treatment 0.202 -0.0217 -1.17 -1.1686 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K20 mock treatment 0.201 -0.0227 -1.22 -1.2223 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K21 mock treatment 0.203 -0.0207 -1.11 -1.1149 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K22 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K23 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base K24 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L01 mock treatment 0.247 0.0233 1.25 1.2496 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L02 mock treatment 0.271 0.0473 2.54 2.5393 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L03 mock treatment 0.26 0.0363 1.95 1.9482 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L04 mock treatment 0.254 0.0303 1.63 1.6258 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L05 mock treatment 0.252 0.0283 1.52 1.5183 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L06 mock treatment 0.255 0.0313 1.68 1.6795 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L07 mock treatment 0.243 0.0193 1.03 1.0346 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L08 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L09 mock treatment 0.244 0.0203 1.09 1.0884 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L10 mock treatment 0.242 0.0183 0.98 0.9809 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L11 mock treatment 0.238 0.0143 0.77 0.766 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L12 mock treatment 0.229 0.00525 0.28 0.2823 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L13 mock treatment 0.219 -0.00475 -0.26 -0.2551 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L14 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L15 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L16 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L17 mock treatment 0.211 -0.0127 -0.68 -0.685 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L18 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L19 mock treatment 0.204 -0.0197 -1.06 -1.0611 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L20 mock treatment 0.213 -0.0107 -0.58 -0.5775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L21 mock treatment 0.194 -0.0297 -1.6 -1.5985 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L22 mock treatment 0.199 -0.0247 -1.33 -1.3298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L23 mock treatment 0.208 -0.0157 -0.85 -0.8462 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base L24 mock treatment 0.199 -0.0247 -1.33 -1.3298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M01 mock treatment 0.238 0.0143 0.77 0.766 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M02 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M03 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M04 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M05 mock treatment 0.236 0.0123 0.66 0.6585 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M06 mock treatment 0.235 0.0113 0.6 0.6047 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M07 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M08 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M09 mock treatment 0.225 0.00125 0.07 0.0674 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M10 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M11 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M12 mock treatment 0.209 -0.0147 -0.79 -0.7924 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M13 mock treatment 0.205 -0.0187 -1.01 -1.0074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M14 mock treatment 0.195 -0.0287 -1.54 -1.5448 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M15 mock treatment 0.192 -0.0317 -1.71 -1.706 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M16 mock treatment 0.193 -0.0307 -1.65 -1.6522 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M17 mock treatment 0.193 -0.0307 -1.65 -1.6522 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M18 mock treatment 0.199 -0.0247 -1.33 -1.3298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M19 mock treatment 0.203 -0.0207 -1.11 -1.1149 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M20 mock treatment 0.197 -0.0267 -1.44 -1.4373 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M21 mock treatment 0.208 -0.0157 -0.85 -0.8462 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M22 mock treatment 0.208 -0.0157 -0.85 -0.8462 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M23 mock treatment 0.201 -0.0227 -1.22 -1.2223 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base M24 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N01 mock treatment 0.247 0.0233 1.25 1.2496 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N02 mock treatment 0.258 0.0343 1.84 1.8407 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N03 mock treatment 0.261 0.0373 2.0 2.0019 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N04 mock treatment 0.257 0.0333 1.79 1.787 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N05 mock treatment 0.247 0.0233 1.25 1.2496 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N06 mock treatment 0.254 0.0303 1.63 1.6258 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N07 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N08 mock treatment 0.241 0.0173 0.93 0.9272 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N09 mock treatment 0.24 0.0163 0.87 0.8734 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N10 mock treatment 0.227 0.00325 0.17 0.1748 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N11 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N12 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N13 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N14 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N15 mock treatment 0.213 -0.0107 -0.58 -0.5775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N16 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N17 mock treatment 0.215 -0.00875 -0.47 -0.47 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N18 mock treatment 0.213 -0.0107 -0.58 -0.5775 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N19 mock treatment 0.212 -0.0117 -0.63 -0.6312 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N20 mock treatment 0.209 -0.0147 -0.79 -0.7924 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N21 mock treatment 0.2 -0.0237 -1.28 -1.2761 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N22 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N23 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base N24 mock treatment 0.214 -0.00975 -0.52 -0.5238 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O01 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O02 mock treatment 0.238 0.0143 0.77 0.766 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O03 mock treatment 0.244 0.0203 1.09 1.0884 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O04 mock treatment 0.23 0.00625 0.34 0.3361 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O05 mock treatment 0.238 0.0143 0.77 0.766 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O06 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O07 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O08 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O09 mock treatment 0.216 -0.00775 -0.42 -0.4163 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O10 mock treatment 0.205 -0.0187 -1.01 -1.0074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O11 mock treatment 0.199 -0.0247 -1.33 -1.3298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O12 mock treatment 0.204 -0.0197 -1.06 -1.0611 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O13 mock treatment 0.2 -0.0237 -1.28 -1.2761 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O14 mock treatment 0.201 -0.0227 -1.22 -1.2223 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O15 mock treatment 0.21 -0.0137 -0.74 -0.7387 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O16 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O17 mock treatment 0.199 -0.0247 -1.33 -1.3298 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O18 mock treatment 0.21 -0.0137 -0.74 -0.7387 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O19 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O20 mock treatment 0.207 -0.0167 -0.9 -0.8999 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O21 mock treatment 0.222 -0.00175 -0.09 -0.0938 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O22 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O23 mock treatment 0.211 -0.0127 -0.68 -0.685 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base O24 mock treatment 0.226 0.00225 0.12 0.1211 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P01 mock treatment 0.255 0.0313 1.68 1.6795 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P02 mock treatment 0.251 0.0273 1.46 1.4646 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P03 mock treatment 0.258 0.0343 1.84 1.8407 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P04 mock treatment 0.252 0.0283 1.52 1.5183 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P05 mock treatment 0.268 0.0443 2.38 2.3781 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P06 mock treatment 0.232 0.00825 0.44 0.4435 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P07 mock treatment 0.239 0.0153 0.82 0.8197 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P08 mock treatment 0.233 0.00925 0.5 0.4973 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P09 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P10 mock treatment 0.221 -0.00275 -0.15 -0.1476 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P11 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P12 mock treatment 0.223 -7.46E-4 -0.04 -0.0401 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P13 mock treatment 0.228 0.00425 0.23 0.2286 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P14 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P15 mock treatment 0.206 -0.0177 -0.95 -0.9537 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P16 mock treatment 0.224 2.54E-4 0.01 0.0136 1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P17 mock treatment 0.217 -0.00675 -0.36 -0.3625 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P18 mock treatment 0.211 -0.0127 -0.68 -0.685 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P19 mock treatment 0.22 -0.00375 -0.2 -0.2013 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P20 mock treatment 0.208 -0.0157 -0.85 -0.8462 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P21 mock treatment 0.216 -0.00775 -0.42 -0.4163 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P22 mock treatment 0.218 -0.00575 -0.31 -0.3088 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P23 mock treatment 0.205 -0.0187 -1.01 -1.0074 -1.0 1035.0015 OpticalDensity(1035.0015) PSACAntagonistScreen 1035.0015.Base P24 mock treatment 0.21 -0.0137 -0.74 -0.7387 -1.0