ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A01 compound treatment 1.06234793E8 884000.0 0.08 1.0220261E8 3750000.0 0.33 0.2858 0.8491 1965040 CMLD1_000001 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A02 compound treatment 1.10383065E8 5030000.0 0.43 9.8360526E7 -95900.0 -0.01 0.3014 0.6933 1965041 CMLD1_000002 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A03 compound treatment 1.03536412E8 -1810000.0 -0.16 1.02123376E8 3670000.0 0.32 0.1161 0.3252 1965042 CMLD1_000003 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A04 compound treatment 9.4316968E7 -1.1E7 -0.95 6.6233855E7 -3.22E7 -2.82 -2.6679 -0.8963 1965043 CMLD1_000004 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A05 compound treatment 1.05842124E8 492000.0 0.04 8.97806E7 -8680000.0 -0.76 -0.5069 -0.6665 1965044 CMLD1_000005 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A06 compound treatment 8.498081E7 -2.04E7 -1.76 7.7726017E7 -2.07E7 -1.81 -2.5269 -0.9999 1965045 CMLD1_000006 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A07 compound treatment 1.10933592E8 5580000.0 0.48 9.7836377E7 -620000.0 -0.05 0.3026 0.6236 1965046 CMLD1_000007 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A08 compound treatment 8.7791314E7 -1.76E7 -1.52 7.3612378E7 -2.48E7 -2.17 -2.6099 -0.9845 1965047 CMLD1_000008 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A09 compound treatment 9.0683209E7 -1.47E7 -1.27 7.9582486E7 -1.89E7 -1.65 -2.0638 -0.9914 1965048 CMLD1_000009 CCCCC=C[C@@H](NC(=O)Oc1cccc(c1)C(F)(F)F)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A10 compound treatment 9.2545978E7 -1.28E7 -1.11 7.8783542E7 -1.97E7 -1.72 -1.9995 -0.9771 1965049 CMLD1_000010 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(OC)cc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A11 compound treatment 1.04827668E8 -523000.0 -0.05 9.7500622E7 -956000.0 -0.08 -0.0911 -0.9581 1965050 CMLD1_000011 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3cccs3)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A12 compound treatment 8.3688661E7 -2.17E7 -1.87 6.4758054E7 -3.37E7 -2.95 -3.4084 -0.9759 1965051 CMLD1_000012 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A13 compound treatment 9.4160482E7 -1.12E7 -0.97 9.5558057E7 -2900000.0 -0.25 -0.8628 -0.8634 1965052 CMLD1_000013 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A14 compound treatment 3.4668998E7 -7.07E7 -6.1 3.1768431E7 -6.67E7 -5.84 -8.4438 -0.9997 1965053 CMLD1_000014 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A15 compound treatment 9.1653597E7 -1.37E7 -1.18 8.7484399E7 -1.1E7 -0.96 -1.5155 -0.9946 1965054 CMLD1_000015 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A16 compound treatment 9.2314083E7 -1.3E7 -1.13 7.8805494E7 -1.97E7 -1.72 -2.0123 -0.9789 1965055 CMLD1_000016 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A17 compound treatment 9.0359327E7 -1.5E7 -1.29 9.9382826E7 926000.0 0.08 -0.8582 -0.6615 1965056 CMLD1_000017 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)C(C)(C)C)c2ccc(cc2)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A18 compound treatment 2.82783E7 -7.71E7 -6.66 2.7128267E7 -7.13E7 -6.24 -9.1212 -0.9995 1965057 CMLD1_000018 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A19 compound treatment 1.06978719E8 1630000.0 0.14 9.5890776E7 -2570000.0 -0.22 -0.0593 -0.2239 1965058 CMLD1_000019 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A20 compound treatment 8.5798909E7 -1.96E7 -1.69 8.8686453E7 -9770000.0 -0.86 -1.7987 -0.9503 1965059 CMLD1_000020 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A21 compound treatment 1.04230564E8 -1120000.0 -0.1 9.1386023E7 -7070000.0 -0.62 -0.5059 -0.8078 1965060 CMLD1_000021 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A22 mock treatment 1.00984499E8 -4370000.0 -0.38 9.5229508E7 -3230000.0 -0.28 -0.4663 -0.9899 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A23 mock treatment 9.8411052E7 -6940000.0 -0.6 8.995991E7 -8500000.0 -0.74 -0.9496 -0.9943 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 A24 mock treatment 1.07657876E8 2310000.0 0.2 1.04035103E8 5580000.0 0.49 0.4862 0.9219 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B01 compound treatment 1.05274993E8 -75400.0 -0.01 9.9279789E7 823000.0 0.07 0.0463 0.6406 1965061 CMLD1_000022 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B02 compound treatment 9.8153926E7 -7200000.0 -0.62 9.3314181E7 -5140000.0 -0.45 -0.7577 -0.9874 1965062 CMLD1_000023 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B03 compound treatment 9.8402165E7 -6950000.0 -0.6 9.3394718E7 -5060000.0 -0.44 -0.7376 -0.9888 1965063 CMLD1_000024 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B04 compound treatment 9.2432532E7 -1.29E7 -1.12 8.5582988E7 -1.29E7 -1.13 -1.5856 -1.0 1965064 CMLD1_000025 CCOC(=O)N(CC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4)S(=O)(=O)c6ccc(C)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B05 compound treatment 9.0968954E7 -1.44E7 -1.24 8.9286802E7 -9170000.0 -0.8 -1.4458 -0.9777 1965065 CMLD1_000026 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B06 compound treatment 1.1246096E8 7110000.0 0.61 1.04271802E8 5820000.0 0.51 0.7942 0.9956 1965066 CMLD1_000027 CC(NP(=O)(c1ccccc1)c2ccccc2)C3(CC(=C)c4ccccc4)CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B07 compound treatment 9.2775344E7 -1.26E7 -1.09 8.5809329E7 -1.26E7 -1.11 -1.5507 -1.0 1965067 CMLD1_000028 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B08 compound treatment 8.9880844E7 -1.55E7 -1.34 7.6338128E7 -2.21E7 -1.94 -2.3136 -0.9836 1965068 CMLD1_000029 COC(=O)C1(C)NCC2=C(C)C(=O)C(C)C2=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B09 compound treatment 8.8701696E7 -1.66E7 -1.44 7.9100293E7 -1.94E7 -1.69 -2.2147 -0.9967 1965069 CMLD1_000030 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B10 compound treatment 8.5708093E7 -1.96E7 -1.7 8.2299483E7 -1.62E7 -1.41 -2.1995 -0.9959 1965070 CMLD1_000031 COC(=O)C1(Cc2ccccc2)NCC3=C(C(C)C)C(=O)C(C)C3=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B11 compound treatment 8.2845138E7 -2.25E7 -1.94 7.6381206E7 -2.21E7 -1.93 -2.7406 -1.0 1965071 CMLD1_000032 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B12 compound treatment 8.2644258E7 -2.27E7 -1.96 7.487884E7 -2.36E7 -2.06 -2.8458 -0.9997 1965072 CMLD1_000033 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCc5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B13 compound treatment 9.0078803E7 -1.53E7 -1.32 8.5218726E7 -1.32E7 -1.16 -1.7519 -0.9979 1965073 CMLD1_000034 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B14 compound treatment 8.5008459E7 -2.03E7 -1.76 8.0133802E7 -1.83E7 -1.6 -2.3763 -0.999 1965074 CMLD1_000035 COc1ccc(COC2OC[C@]3(C)[C@@H]4[C@H]2CCC5C(CO)C(CO)[C@@H](C)C(=C54)CN3C(=O)OC(C)(C)C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B15 compound treatment 8.7059549E7 -1.83E7 -1.58 8.7099839E7 -1.14E7 -0.99 -1.8199 -0.9751 1965075 CMLD1_000036 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B16 compound treatment 8.584023E7 -1.95E7 -1.69 8.2416708E7 -1.6E7 -1.4 -2.1842 -0.9959 1965076 CMLD1_000037 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(F)cc5)C=C21)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B17 compound treatment 8.2468879E7 -2.29E7 -1.98 8.5550574E7 -1.29E7 -1.13 -2.1961 -0.9648 1965077 CMLD1_000038 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B18 compound treatment 8.6156079E7 -1.92E7 -1.66 8.2613636E7 -1.58E7 -1.39 -2.1527 -0.9961 1965078 CMLD1_000039 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B19 compound treatment 9.655267E7 -8800000.0 -0.76 9.196978E7 -6490000.0 -0.57 -0.9387 -0.9897 1965079 CMLD1_000040 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B20 compound treatment 8.8250094E7 -1.71E7 -1.48 8.7548161E7 -1.09E7 -0.95 -1.7194 -0.9777 1965080 CMLD1_000041 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B21 compound treatment 1.01259327E8 -4090000.0 -0.35 9.6691172E7 -1770000.0 -0.15 -0.3591 -0.9312 1965081 CMLD1_000042 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B22 mock treatment 8.934649E7 -1.6E7 -1.38 8.5199667E7 -1.33E7 -1.16 -1.7978 -0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B23 mock treatment 1.04172297E8 -1180000.0 -0.1 9.920406E7 748000.0 0.07 -0.0257 -0.2123 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 B24 mock treatment 1.02933289E8 -2420000.0 -0.21 9.8783026E7 327000.0 0.03 -0.1274 -0.6047 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C01 compound treatment 1.11177322E8 5830000.0 0.5 9.5285189E7 -3170000.0 -0.28 0.1596 0.2777 1965082 CMLD1_000043 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC1(CCC2CC1=O)C2(C)C)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C02 compound treatment 2.1147911E7 -8.42E7 -7.27 2.0489438E7 -7.8E7 -6.82 -9.9676 -0.9995 1965083 CMLD1_000044 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C03 compound treatment 1.01811521E8 -3540000.0 -0.31 9.5367383E7 -3090000.0 -0.27 -0.4073 -0.9981 1965084 CMLD1_000045 CCCC=C(CCC)[C@@H](NC(=O)CCc1ccccc1)c2ccc(cc2)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C04 compound treatment 9.4026364E7 -1.13E7 -0.98 7.3154705E7 -2.53E7 -2.21 -2.2574 -0.9325 1965085 CMLD1_000046 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C05 compound treatment 1.129417E8 7590000.0 0.66 1.00721144E8 2260000.0 0.2 0.6038 0.8815 1965086 CMLD1_000047 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C06 compound treatment 8.9537949E7 -1.58E7 -1.37 7.9228718E7 -1.92E7 -1.68 -2.1556 -0.9946 1965087 CMLD1_000048 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C07 compound treatment 9.7095715E7 -8250000.0 -0.71 7.2895717E7 -2.56E7 -2.24 -2.086 -0.8884 1965088 CMLD1_000049 CCCCC=C[C@@H](NC(=O)CCc1ccccc1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C08 compound treatment 9.2544725E7 -1.28E7 -1.11 7.2097256E7 -2.64E7 -2.31 -2.4133 -0.9433 1965089 CMLD1_000050 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(C)onc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C09 compound treatment 1.0759421E8 2240000.0 0.19 9.560614E7 -2850000.0 -0.25 -0.0393 -0.1246 1965090 CMLD1_000051 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C10 compound treatment 9.5934767E7 -9420000.0 -0.81 8.5748058E7 -1.27E7 -1.11 -1.3615 -0.9882 1965091 CMLD1_000052 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C11 compound treatment 9.2956461E7 -1.24E7 -1.07 7.9481746E7 -1.9E7 -1.66 -1.9312 -0.9774 1965092 CMLD1_000053 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccccc3)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C12 compound treatment 8.4608973E7 -2.07E7 -1.79 8.1527994E7 -1.69E7 -1.48 -2.3144 -0.9955 1965093 CMLD1_000054 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C13 compound treatment 1.06458377E8 1110000.0 0.1 9.7986774E7 -470000.0 -0.04 0.0386 0.3706 1965094 CMLD1_000055 CCCCC=C[C@@H](NC(=O)c1ccccc1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C14 compound treatment 6.1306344E7 -4.4E7 -3.8 4.722344E7 -5.12E7 -4.48 -5.8605 -0.9967 1965095 CMLD1_000056 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C15 compound treatment 1.0239362E8 -2960000.0 -0.26 9.700414E7 -1450000.0 -0.13 -0.2705 -0.9481 1965096 CMLD1_000057 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C16 compound treatment 9.0546497E7 -1.48E7 -1.28 8.8324344E7 -1.01E7 -0.89 -1.5312 -0.984 1965097 CMLD1_000058 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C17 compound treatment 8.690898E7 -1.84E7 -1.59 7.4994151E7 -2.35E7 -2.05 -2.5782 -0.9921 1965098 CMLD1_000059 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NS(=O)(=O)c3cccc4cccnc34)c5ccc(cc5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C18 compound treatment 1.02896223E8 -2450000.0 -0.21 9.3973449E7 -4480000.0 -0.39 -0.4273 -0.9582 1965099 CMLD1_000060 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(OC)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C19 compound treatment 1.02418516E8 -2930000.0 -0.25 9.5123816E7 -3330000.0 -0.29 -0.3853 -0.9975 1965100 CMLD1_000061 CC(C)(C)C(=O)N[C@@H](c1ccc(Cl)cc1)[C@]2(C)C[C@H]2C3CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C20 compound treatment 1.01582098E8 -3770000.0 -0.33 8.7902423E7 -1.06E7 -0.92 -0.8833 -0.9019 1965101 CMLD1_000062 CCCCC=C[C@@H](NC(=O)OCC#C)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C21 compound treatment 1.16484639E8 1.11E7 0.96 1.04033028E8 5580000.0 0.49 1.0251 0.9506 1965060 CMLD1_000063 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C22 mock treatment 9.8130572E7 -7220000.0 -0.62 9.4809267E7 -3650000.0 -0.32 -0.6667 -0.9516 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C23 mock treatment 1.07105404E8 1750000.0 0.15 9.4215069E7 -4240000.0 -0.37 -0.1553 -0.3873 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 C24 mock treatment 1.10254719E8 4900000.0 0.42 1.01364597E8 2910000.0 0.25 0.4795 0.9703 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D01 compound treatment 1.04287294E8 -1060000.0 -0.09 9.4513785E7 -3940000.0 -0.35 -0.3089 -0.8652 1965102 CMLD1_000064 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D02 compound treatment 9.8372172E7 -6980000.0 -0.6 9.1943165E7 -6510000.0 -0.57 -0.8293 -0.9996 1965103 CMLD1_000065 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D03 compound treatment 9.9718338E7 -5630000.0 -0.49 8.7951223E7 -1.05E7 -0.92 -0.9941 -0.9557 1965104 CMLD1_000066 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D04 compound treatment 1.16537667E8 1.12E7 0.97 1.04634313E8 6180000.0 0.54 1.0656 0.9624 1965105 CMLD1_000067 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D05 compound treatment 9.3312434E7 -1.2E7 -1.04 8.3479558E7 -1.5E7 -1.31 -1.662 -0.9934 1965106 CMLD1_000068 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D06 compound treatment 9.3449753E7 -1.19E7 -1.03 7.9671087E7 -1.88E7 -1.64 -1.8893 -0.9744 1965107 CMLD1_000069 CC(=O)N1CC2(CC2)CC1c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D07 compound treatment 8.8593761E7 -1.68E7 -1.45 8.6005527E7 -1.25E7 -1.09 -1.7939 -0.9902 1965108 CMLD1_000070 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D08 compound treatment 9.1622255E7 -1.37E7 -1.19 8.4322432E7 -1.41E7 -1.24 -1.7131 -0.9998 1965109 CMLD1_000071 COC(=O)C1(C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D09 compound treatment 8.9278354E7 -1.61E7 -1.39 8.6457658E7 -1.2E7 -1.05 -1.7241 -0.9905 1965110 CMLD1_000072 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCn7cc(nc7C)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D10 compound treatment 8.2886354E7 -2.25E7 -1.94 7.2258544E7 -2.62E7 -2.29 -2.9932 -0.9966 1965111 CMLD1_000073 COC(=O)C1(Cc2ccccc2)NCC3=C(C(=O)C(C)C3=C1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D11 compound treatment 9.5591875E7 -9760000.0 -0.84 8.8041229E7 -1.04E7 -0.91 -1.2405 -0.9992 1965112 CMLD1_000074 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D12 compound treatment 8.827329E7 -1.71E7 -1.47 8.5392128E7 -1.31E7 -1.14 -1.8515 -0.9921 1965113 CMLD1_000075 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccco5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D13 compound treatment 7.5831769E7 -2.95E7 -2.55 6.81883E7 -3.03E7 -2.65 -3.676 -0.9998 1965057 CMLD1_000076 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D14 compound treatment 8.8020088E7 -1.73E7 -1.5 8.194433E7 -1.65E7 -1.45 -2.0803 -0.9998 1965114 CMLD1_000077 C[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D15 compound treatment 9.624527E7 -9110000.0 -0.79 9.144528E7 -7010000.0 -0.61 -0.99 -0.9925 1965115 CMLD1_000078 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D16 compound treatment 9.0416914E7 -1.49E7 -1.29 8.8533001E7 -9920000.0 -0.87 -1.5262 -0.9815 1965116 CMLD1_000079 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(F)cc6)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D17 compound treatment 9.4015948E7 -1.13E7 -0.98 8.3290125E7 -1.52E7 -1.33 -1.6308 -0.9888 1965117 CMLD1_000080 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D18 compound treatment 9.7998504E7 -7350000.0 -0.64 8.9106918E7 -9350000.0 -0.82 -1.0276 -0.9921 1965118 CMLD1_000081 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D19 compound treatment 9.6043103E7 -9310000.0 -0.8 9.7267251E7 -1190000.0 -0.1 -0.642 -0.792 1965119 CMLD1_000082 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D20 compound treatment 1.01792776E8 -3560000.0 -0.31 8.6728928E7 -1.17E7 -1.03 -0.943 -0.8802 1965120 CMLD1_000083 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D21 compound treatment 1.0213845E8 -3210000.0 -0.28 9.278202E7 -5670000.0 -0.5 -0.5473 -0.9622 1965121 CMLD1_000084 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D22 mock treatment 9.7365493E7 -7980000.0 -0.69 9.6624391E7 -1830000.0 -0.16 -0.6011 -0.8489 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D23 mock treatment 1.07238919E8 1890000.0 0.16 9.6479289E7 -1980000.0 -0.17 -0.007 -0.0295 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 D24 mock treatment 1.07992467E8 2640000.0 0.23 1.00823795E8 2370000.0 0.21 0.3079 0.9988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E01 compound treatment 1.11587413E8 6240000.0 0.54 9.3238037E7 -5220000.0 -0.46 0.058 0.0821 1965122 CMLD1_000085 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E02 compound treatment 1.12438965E8 7090000.0 0.61 9.9018286E7 562000.0 0.05 0.4677 0.7614 1965123 CMLD1_000086 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E03 compound treatment 1.09381323E8 4030000.0 0.35 9.6508112E7 -1950000.0 -0.17 0.1256 0.324 1965124 CMLD1_000087 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E04 compound treatment 1.00951516E8 -4400000.0 -0.38 8.7511354E7 -1.09E7 -0.96 -0.946 -0.918 1965125 CMLD1_000088 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E05 compound treatment 1.01696775E8 -3650000.0 -0.32 9.4152543E7 -4300000.0 -0.38 -0.4895 -0.9961 1965126 CMLD1_000089 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E06 compound treatment 9.5312492E7 -1.0E7 -0.87 8.1378284E7 -1.71E7 -1.49 -1.6699 -0.9665 1965127 CMLD1_000090 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E07 compound treatment 9.0483179E7 -1.49E7 -1.28 7.1360445E7 -2.71E7 -2.37 -2.5848 -0.9585 1965128 CMLD1_000091 CCCCC=C[C@@H](NC(=O)C(C)(C)C)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E08 compound treatment 8.915811E7 -1.62E7 -1.4 7.5975169E7 -2.25E7 -1.97 -2.3802 -0.986 1965129 CMLD1_000092 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E09 compound treatment 1.00323369E8 -5030000.0 -0.43 9.3081027E7 -5380000.0 -0.47 -0.6397 -0.9992 1965130 CMLD1_000093 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E10 compound treatment 8.7532501E7 -1.78E7 -1.54 7.6366431E7 -2.21E7 -1.93 -2.4552 -0.9936 1965131 CMLD1_000094 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E11 compound treatment 9.6886293E7 -8460000.0 -0.73 8.9783931E7 -8670000.0 -0.76 -1.0536 -0.9998 1965060 CMLD1_000095 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E12 compound treatment 8.5913861E7 -1.94E7 -1.68 7.9832177E7 -1.86E7 -1.63 -2.3396 -0.9999 1965132 CMLD1_000096 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E13 compound treatment 9.4733621E7 -1.06E7 -0.92 8.9665111E7 -8790000.0 -0.77 -1.1925 -0.9962 1965133 CMLD1_000097 CCCCC=C[C@@H](NC(=O)OCc1ccccc1Cl)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E14 compound treatment 9.3004036E7 -1.23E7 -1.07 8.6443685E7 -1.2E7 -1.05 -1.4974 -1.0 1965134 CMLD1_000098 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E15 compound treatment 9.9174307E7 -6180000.0 -0.53 9.4864351E7 -3590000.0 -0.31 -0.5995 -0.9682 1965135 CMLD1_000099 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E16 compound treatment 9.4031076E7 -1.13E7 -0.98 8.8272307E7 -1.02E7 -0.89 -1.3216 -0.9989 1965136 CMLD1_000100 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E17 compound treatment 1.10178319E8 4830000.0 0.42 9.9860754E7 1400000.0 0.12 0.3818 0.8782 1965137 CMLD1_000101 CC(=CC1CCCCC1)[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E18 compound treatment 4.6301191E7 -5.9E7 -5.1 4.5464111E7 -5.3E7 -4.64 -6.8858 -0.9989 1965138 CMLD1_000102 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E19 compound treatment 8.7985488E7 -1.74E7 -1.5 7.9385546E7 -1.91E7 -1.67 -2.2407 -0.9986 1965139 CMLD1_000103 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccc(cc3)c4ccccc4)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E20 compound treatment 1.00063306E8 -5290000.0 -0.46 9.0630542E7 -7830000.0 -0.68 -0.8072 -0.9806 1965140 CMLD1_000104 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E21 compound treatment 1.06747915E8 1400000.0 0.12 1.00442255E8 1990000.0 0.17 0.2082 0.9841 1965141 CMLD1_000105 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccccc2)c3cccc(Cl)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E22 mock treatment 1.01513168E8 -3840000.0 -0.33 9.5562288E7 -2890000.0 -0.25 -0.4135 -0.9912 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E23 mock treatment 1.04309569E8 -1040000.0 -0.09 9.8928664E7 472000.0 0.04 -0.0343 -0.3471 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 E24 mock treatment 1.06293069E8 943000.0 0.08 1.01164437E8 2710000.0 0.24 0.2252 0.8985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F01 compound treatment 1.04981145E8 -369000.0 -0.03 8.8106255E7 -1.04E7 -0.91 -0.6631 -0.7316 1965142 CMLD1_000106 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CCOCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F02 compound treatment 9.8040693E7 -7310000.0 -0.63 9.0620892E7 -7840000.0 -0.69 -0.9313 -0.9991 1965143 CMLD1_000107 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F03 compound treatment 1.00738317E8 -4610000.0 -0.4 9.5477216E7 -2980000.0 -0.26 -0.466 -0.9789 1965144 CMLD1_000108 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F04 compound treatment 1.16960419E8 1.16E7 1.0 1.04498506E8 6040000.0 0.53 1.083 0.9553 1965145 CMLD1_000109 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5cccc(OC)c5)CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F05 compound treatment 9.5325687E7 -1.0E7 -0.87 9.099178E7 -7460000.0 -0.65 -1.0742 -0.9904 1965146 CMLD1_000110 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F06 compound treatment 9.3422125E7 -1.19E7 -1.03 9.1892676E7 -6560000.0 -0.57 -1.1347 -0.9619 1965147 CMLD1_000111 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F07 compound treatment 9.4719405E7 -1.06E7 -0.92 9.1055977E7 -7400000.0 -0.65 -1.1073 -0.9854 1965148 CMLD1_000112 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F08 compound treatment 9.0864443E7 -1.45E7 -1.25 8.7125036E7 -1.13E7 -0.99 -1.586 -0.9934 1965149 CMLD1_000113 CCCCCC1=C2CNC(C)(C=C2C(C)C1=O)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F09 compound treatment 9.5233311E7 -1.01E7 -0.87 8.9944052E7 -8510000.0 -0.74 -1.1447 -0.9968 1965150 CMLD1_000114 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F10 compound treatment 8.8234685E7 -1.71E7 -1.48 8.6432085E7 -1.2E7 -1.05 -1.7895 -0.9861 1965151 CMLD1_000115 CCCCCC1=C2CNC(Cc3ccccc3)(C=C2C(C)C1=O)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F11 compound treatment 9.2903157E7 -1.24E7 -1.08 8.9310496E7 -9150000.0 -0.8 -1.3262 -0.9894 1965152 CMLD1_000116 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F12 compound treatment 8.7103729E7 -1.82E7 -1.58 8.9184851E7 -9270000.0 -0.81 -1.6882 -0.9524 1965153 CMLD1_000117 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F13 compound treatment 8.5176506E7 -2.02E7 -1.74 7.7463785E7 -2.1E7 -1.84 -2.5312 -0.9996 1965154 CMLD1_000118 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F14 compound treatment 9.2895796E7 -1.25E7 -1.08 8.9015498E7 -9440000.0 -0.83 -1.3449 -0.9915 1965155 CMLD1_000119 C[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F15 compound treatment 9.6058462E7 -9290000.0 -0.8 9.2316356E7 -6140000.0 -0.54 -0.9475 -0.981 1965156 CMLD1_000120 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F16 compound treatment 9.2525698E7 -1.28E7 -1.11 8.9673269E7 -8780000.0 -0.77 -1.3268 -0.9841 1965157 CMLD1_000121 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(cc5)C(F)(F)F)C=C21)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F17 compound treatment 1.06440818E8 1090000.0 0.09 9.9462105E7 1010000.0 0.09 0.1288 0.9994 1965158 CMLD1_000122 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F18 compound treatment 1.03038163E8 -2310000.0 -0.2 9.8615492E7 159000.0 0.01 -0.1314 -0.6562 1965150 CMLD1_000123 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F19 compound treatment 1.00378542E8 -4970000.0 -0.43 9.4865033E7 -3590000.0 -0.31 -0.5259 -0.9882 1965159 CMLD1_000124 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F20 compound treatment 9.793392E7 -7420000.0 -0.64 9.4425584E7 -4030000.0 -0.35 -0.7024 -0.9605 1965160 CMLD1_000125 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F21 compound treatment 9.6023652E7 -9330000.0 -0.81 9.0331924E7 -8120000.0 -0.71 -1.0724 -0.9981 1965161 CMLD1_000126 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F22 mock treatment 1.00591256E8 -4760000.0 -0.41 9.5037615E7 -3420000.0 -0.3 -0.5022 -0.9878 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F23 mock treatment 1.05635978E8 286000.0 0.02 1.01305721E8 2850000.0 0.25 0.1938 0.7733 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 F24 mock treatment 1.05958992E8 609000.0 0.05 9.9902589E7 1450000.0 0.13 0.1267 0.9242 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G01 compound treatment 1.10934454E8 5580000.0 0.48 9.8591572E7 135000.0 0.01 0.3494 0.7242 1965162 CMLD1_000127 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G02 compound treatment 9.9763507E7 -5590000.0 -0.48 8.5822771E7 -1.26E7 -1.11 -1.123 -0.9309 1965163 CMLD1_000128 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G03 compound treatment 8.8140979E7 -1.72E7 -1.49 7.4070825E7 -2.44E7 -2.13 -2.5601 -0.9844 1965164 CMLD1_000129 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccccc1)c2ccc(cc2)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G04 compound treatment 9.2829724E7 -1.25E7 -1.08 8.1383573E7 -1.71E7 -1.49 -1.8212 -0.9874 1965165 CMLD1_000130 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G05 compound treatment 1.05506941E8 157000.0 0.01 9.2421612E7 -6030000.0 -0.53 -0.3639 -0.6888 1965166 CMLD1_000131 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G06 compound treatment 9.355989E7 -1.18E7 -1.02 8.1292507E7 -1.72E7 -1.5 -1.7823 -0.9821 1965167 CMLD1_000132 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G07 compound treatment 9.9121922E7 -6230000.0 -0.54 9.1343158E7 -7110000.0 -0.62 -0.8206 -0.9974 1965168 CMLD1_000133 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G08 compound treatment 9.0048794E7 -1.53E7 -1.32 7.7594075E7 -2.09E7 -1.83 -2.2256 -0.9874 1965169 CMLD1_000134 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccccc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G09 compound treatment 9.4104217E7 -1.12E7 -0.97 8.9381175E7 -9080000.0 -0.79 -1.2485 -0.995 1965170 CMLD1_000135 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G10 compound treatment 8.8473323E7 -1.69E7 -1.46 7.9088355E7 -1.94E7 -1.7 -2.2293 -0.9972 1965171 CMLD1_000136 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)c(F)c(F)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G11 compound treatment 1.10006822E8 4660000.0 0.4 1.05106708E8 6650000.0 0.58 0.6959 0.9837 1965172 CMLD1_000137 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G12 compound treatment 8.4937584E7 -2.04E7 -1.76 7.4685728E7 -2.38E7 -2.08 -2.7177 -0.9966 1965173 CMLD1_000138 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G13 compound treatment 1.046607E8 -690000.0 -0.06 9.6155939E7 -2300000.0 -0.2 -0.1845 -0.8787 1965174 CMLD1_000139 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G14 compound treatment 9.7900524E7 -7450000.0 -0.64 8.8702027E7 -9750000.0 -0.85 -1.0586 -0.9903 1965175 CMLD1_000140 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G15 compound treatment 1.01476013E8 -3870000.0 -0.33 8.7860472E7 -1.06E7 -0.93 -0.8924 -0.9051 1965176 CMLD1_000141 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G16 compound treatment 9.6636005E7 -8710000.0 -0.75 8.9709518E7 -8750000.0 -0.77 -1.0735 -1.0 1965177 CMLD1_000142 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G17 compound treatment 1.00889931E8 -4460000.0 -0.39 9.3993884E7 -4460000.0 -0.39 -0.5486 -1.0 1965178 CMLD1_000143 CC(=CC1CCCCC1)[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G18 compound treatment 9.9727948E7 -5620000.0 -0.49 9.1090419E7 -7370000.0 -0.64 -0.7992 -0.9902 1965179 CMLD1_000144 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G19 compound treatment 1.05684964E8 335000.0 0.03 9.556414E7 -2890000.0 -0.25 -0.1586 -0.6223 1965180 CMLD1_000145 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G20 compound treatment 1.02056727E8 -3290000.0 -0.28 9.5992268E7 -2460000.0 -0.22 -0.3537 -0.9907 1965181 CMLD1_000146 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G21 compound treatment 1.02098285E8 -3250000.0 -0.28 9.3160079E7 -5300000.0 -0.46 -0.5264 -0.9712 1965182 CMLD1_000147 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G22 mock treatment 1.05118741E8 -232000.0 -0.02 1.00142034E8 1690000.0 0.15 0.0902 0.6056 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G23 mock treatment 1.06301357E8 951000.0 0.08 9.5451554E7 -3000000.0 -0.26 -0.1279 -0.4642 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 G24 mock treatment 1.07002109E8 1650000.0 0.14 1.00904965E8 2450000.0 0.21 0.2524 0.9805 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H01 compound treatment 1.12017401E8 6670000.0 0.58 1.0073369E8 2280000.0 0.2 0.5481 0.8995 1965183 CMLD1_000148 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H02 compound treatment 9.7158012E7 -8190000.0 -0.71 8.6713956E7 -1.17E7 -1.03 -1.227 -0.9834 1965184 CMLD1_000149 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H03 compound treatment 9.9958702E7 -5390000.0 -0.47 9.644178E7 -2010000.0 -0.18 -0.454 -0.9117 1965185 CMLD1_000150 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H04 compound treatment 1.16555659E8 1.12E7 0.97 1.04702379E8 6250000.0 0.55 1.0709 0.9634 1965186 CMLD1_000151 CCCC[C@H]1C[C@@H]1[C@@H]2N(C[C@](O)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H05 compound treatment 9.1760841E7 -1.36E7 -1.17 8.3018144E7 -1.54E7 -1.35 -1.7854 -0.9975 1965187 CMLD1_000152 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H06 compound treatment 1.01149264E8 -4200000.0 -0.36 9.9053986E7 598000.0 0.05 -0.2196 -0.599 1965147 CMLD1_000153 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H07 compound treatment 9.8347086E7 -7000000.0 -0.6 9.340421E7 -5050000.0 -0.44 -0.7404 -0.9881 1965188 CMLD1_000154 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H08 compound treatment 9.5941843E7 -9410000.0 -0.81 8.7868655E7 -1.06E7 -0.93 -1.2298 -0.9979 1965189 CMLD1_000155 CCCC1(NCC2=C(C)C(=O)C(C)C2=C1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H09 compound treatment 9.8482989E7 -6870000.0 -0.59 9.2873399E7 -5580000.0 -0.49 -0.7649 -0.9954 1965190 CMLD1_000156 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H10 compound treatment 8.9617682E7 -1.57E7 -1.36 8.5203464E7 -1.33E7 -1.16 -1.781 -0.9969 1965191 CMLD1_000157 COC(=O)C1(CC(C)C)NCC2=C(C)C(=O)C(C)C2=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H11 compound treatment 9.3379953E7 -1.2E7 -1.03 9.0363192E7 -8090000.0 -0.71 -1.2319 -0.983 1965192 CMLD1_000158 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H12 compound treatment 9.0214211E7 -1.51E7 -1.31 8.626963E7 -1.22E7 -1.07 -1.6786 -0.9949 1965193 CMLD1_000159 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H13 compound treatment 9.8855306E7 -6500000.0 -0.56 9.2352619E7 -6100000.0 -0.53 -0.7744 -0.9997 1965194 CMLD1_000160 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H14 compound treatment 9.0472309E7 -1.49E7 -1.29 8.9990202E7 -8470000.0 -0.74 -1.4326 -0.9658 1965195 CMLD1_000161 C[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H15 compound treatment 8.8525592E7 -1.68E7 -1.45 9.0807643E7 -7650000.0 -0.67 -1.5009 -0.9381 1965196 CMLD1_000162 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H16 compound treatment 9.4048217E7 -1.13E7 -0.98 8.8333167E7 -1.01E7 -0.89 -1.3167 -0.9988 1965197 CMLD1_000163 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(cc6)C(F)(F)F)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H17 compound treatment 9.6830002E7 -8520000.0 -0.74 9.2483017E7 -5970000.0 -0.52 -0.89 -0.986 1965198 CMLD1_000164 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H18 compound treatment 9.1658533E7 -1.37E7 -1.18 8.530102E7 -1.32E7 -1.15 -1.6503 -0.9999 1965199 CMLD1_000165 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H19 compound treatment 9.9611458E7 -5740000.0 -0.5 9.2847021E7 -5610000.0 -0.49 -0.6976 -1.0 1965200 CMLD1_000166 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H20 compound treatment 1.02446951E8 -2900000.0 -0.25 9.452638E7 -3930000.0 -0.34 -0.4205 -0.988 1965201 CMLD1_000167 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H21 compound treatment 1.01451265E8 -3900000.0 -0.34 9.8955516E7 499000.0 0.04 -0.2073 -0.6103 1965202 CMLD1_000168 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H22 mock treatment 1.03488753E8 -1860000.0 -0.16 9.2668328E7 -5790000.0 -0.51 -0.4719 -0.8879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H23 mock treatment 1.05287593E8 -62800.0 -0.01 9.5046621E7 -3410000.0 -0.3 -0.2149 -0.7198 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 H24 mock treatment 1.07280822E8 1930000.0 0.17 9.9844622E7 1390000.0 0.12 0.2038 0.9879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I01 compound treatment 1.11392713E8 6040000.0 0.52 9.5386926E7 -3070000.0 -0.27 0.1791 0.3051 1965203 CMLD1_000169 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I02 compound treatment 9.8770771E7 -6580000.0 -0.57 8.152952E7 -1.69E7 -1.48 -1.4494 -0.9135 1965204 CMLD1_000170 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I03 compound treatment 9.7632857E7 -7720000.0 -0.67 8.7344782E7 -1.11E7 -0.97 -1.159 -0.983 1965205 CMLD1_000171 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I04 compound treatment 9.5332147E7 -1.0E7 -0.87 8.53115E7 -1.31E7 -1.15 -1.4253 -0.9901 1965206 CMLD1_000172 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I05 compound treatment 1.17704209E8 1.24E7 1.07 1.04355296E8 5900000.0 0.52 1.1195 0.9445 1965207 CMLD1_000173 CCCC=C(CCC)[C@@H](NC(=O)c1ccco1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I06 compound treatment 9.4883064E7 -1.05E7 -0.9 8.5682039E7 -1.28E7 -1.12 -1.4298 -0.9945 1965208 CMLD1_000174 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I07 compound treatment 1.09437306E8 4090000.0 0.35 1.01259107E8 2800000.0 0.25 0.423 0.9842 1965209 CMLD1_000175 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I08 compound treatment 8.8456634E7 -1.69E7 -1.46 8.0568293E7 -1.79E7 -1.57 -2.1388 -0.9994 1965210 CMLD1_000176 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I09 compound treatment 9.8196078E7 -7150000.0 -0.62 9.5812756E7 -2640000.0 -0.23 -0.6005 -0.9102 1965211 CMLD1_000177 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I10 compound treatment 8.2913459E7 -2.24E7 -1.94 7.6339199E7 -2.21E7 -1.94 -2.739 -1.0 1965212 CMLD1_000178 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I11 compound treatment 1.09969093E8 4620000.0 0.4 1.03992858E8 5540000.0 0.48 0.6247 0.9953 1965213 CMLD1_000179 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I12 compound treatment 9.2990224E7 -1.24E7 -1.07 8.3976456E7 -1.45E7 -1.27 -1.651 -0.9964 1965214 CMLD1_000180 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I13 compound treatment 9.9916073E7 -5430000.0 -0.47 9.2605233E7 -5850000.0 -0.51 -0.694 -0.9991 1965215 CMLD1_000181 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I14 compound treatment 9.4396738E7 -1.1E7 -0.95 8.6696019E7 -1.18E7 -1.03 -1.3968 -0.9991 1965216 CMLD1_000182 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I15 compound treatment 1.13276275E8 7930000.0 0.68 1.05523919E8 7070000.0 0.62 0.9214 0.9987 1965217 CMLD1_000183 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I16 compound treatment 9.793859E7 -7410000.0 -0.64 9.2855468E7 -5600000.0 -0.49 -0.7993 -0.9913 1965218 CMLD1_000184 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I17 compound treatment 1.10919997E8 5570000.0 0.48 1.04480144E8 6020000.0 0.53 0.7129 0.999 1965219 CMLD1_000185 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccccc2)[C@]3(C)C[C@H]3C4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I18 compound treatment 9.8237175E7 -7110000.0 -0.61 9.0392812E7 -8060000.0 -0.71 -0.9334 -0.9976 1965220 CMLD1_000186 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I19 compound treatment 1.02325285E8 -3030000.0 -0.26 9.8441573E7 -14900.0 0.0 -0.1857 -0.7106 1965221 CMLD1_000187 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccccc3C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I20 compound treatment 1.01749882E8 -3600000.0 -0.31 9.6963722E7 -1490000.0 -0.13 -0.3123 -0.9258 1965222 CMLD1_000188 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I21 compound treatment 9.3937913E7 -1.14E7 -0.99 8.7635382E7 -1.08E7 -0.95 -1.3667 -0.9998 1965223 CMLD1_000189 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CC6CC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I22 mock treatment 9.9840836E7 -5510000.0 -0.48 9.5583831E7 -2870000.0 -0.25 -0.5143 -0.9555 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I23 mock treatment 1.06083395E8 733000.0 0.06 9.9409217E7 953000.0 0.08 0.1037 0.9908 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 I24 mock treatment 1.0655789E8 1210000.0 0.1 1.00822266E8 2370000.0 0.21 0.2202 0.9496 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J01 compound treatment 1.12480574E8 7130000.0 0.62 9.9827475E7 1370000.0 0.12 0.5203 0.8293 1965224 CMLD1_000190 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J02 compound treatment 5.1054768E7 -5.43E7 -4.69 5.2401792E7 -4.61E7 -4.03 -6.1661 -0.9972 1965225 CMLD1_000191 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J03 compound treatment 9.9156526E7 -6190000.0 -0.53 9.9158975E7 703000.0 0.06 -0.3348 -0.6217 1965226 CMLD1_000192 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J04 compound treatment 8.6898846E7 -1.85E7 -1.59 8.5510283E7 -1.29E7 -1.13 -1.9281 -0.986 1965227 CMLD1_000193 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@](CO)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J05 compound treatment 9.8197696E7 -7150000.0 -0.62 9.4421722E7 -4030000.0 -0.35 -0.6865 -0.9648 1965228 CMLD1_000194 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J06 compound treatment 9.3845764E7 -1.15E7 -0.99 9.3227529E7 -5230000.0 -0.46 -1.0262 -0.9381 1965229 CMLD1_000195 OC1(CN(CC2(CC2)C1)P(=O)(c3ccccc3)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J07 compound treatment 9.9183925E7 -6170000.0 -0.53 9.3352004E7 -5100000.0 -0.45 -0.6925 -0.9962 1965230 CMLD1_000196 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J08 compound treatment 9.5714931E7 -9640000.0 -0.83 8.9776708E7 -8680000.0 -0.76 -1.1256 -0.999 1965231 CMLD1_000197 CCCC1(NCC2=C(C(C)C)C(=O)C(C)C2=C1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J09 compound treatment 9.4719776E7 -1.06E7 -0.92 9.4215654E7 -4240000.0 -0.37 -0.9117 -0.9206 1965232 CMLD1_000198 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J10 compound treatment 9.0160985E7 -1.52E7 -1.31 8.8177682E7 -1.03E7 -0.9 -1.5638 -0.9831 1965233 CMLD1_000199 COC(=O)C1(CC(C)C)NCC2=C(C(C)C)C(=O)C(C)C2=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J11 compound treatment 9.5783038E7 -9570000.0 -0.83 8.7274539E7 -1.12E7 -0.98 -1.2763 -0.9965 1965234 CMLD1_000200 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J12 compound treatment 9.1244887E7 -1.41E7 -1.22 8.4863288E7 -1.36E7 -1.19 -1.7027 -0.9999 1965235 CMLD1_000201 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cccc(Cl)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J13 compound treatment 1.01711404E8 -3640000.0 -0.31 9.5767498E7 -2690000.0 -0.24 -0.3887 -0.9898 1965236 CMLD1_000202 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J14 compound treatment 9.5014845E7 -1.03E7 -0.89 9.1857242E7 -6600000.0 -0.58 -1.0396 -0.9778 1965237 CMLD1_000203 CC[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J15 compound treatment 9.5808947E7 -9540000.0 -0.82 8.9798949E7 -8660000.0 -0.76 -1.1185 -0.9991 1965238 CMLD1_000204 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J16 compound treatment 8.9897354E7 -1.55E7 -1.33 8.8565648E7 -9890000.0 -0.87 -1.5559 -0.978 1965239 CMLD1_000205 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J17 compound treatment 1.0074121E8 -4610000.0 -0.4 9.7429877E7 -1030000.0 -0.09 -0.345 -0.8454 1965240 CMLD1_000206 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J18 compound treatment 9.5166119E7 -1.02E7 -0.88 9.1518439E7 -6940000.0 -0.61 -1.0514 -0.9836 1965241 CMLD1_000207 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J19 compound treatment 1.01873412E8 -3480000.0 -0.3 9.8132029E7 -324000.0 -0.03 -0.2324 -0.7705 1965242 CMLD1_000208 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J20 compound treatment 9.5464099E7 -9890000.0 -0.85 9.349519E7 -4960000.0 -0.43 -0.9108 -0.9508 1965243 CMLD1_000209 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J21 compound treatment 1.02170688E8 -3180000.0 -0.27 1.0016851E8 1710000.0 0.15 -0.0883 -0.2821 1965244 CMLD1_000210 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J22 mock treatment 9.576644E7 -9580000.0 -0.83 9.5776317E7 -2680000.0 -0.23 -0.7512 -0.8731 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J23 mock treatment 1.02184651E8 -3170000.0 -0.27 9.6328757E7 -2130000.0 -0.19 -0.325 -0.9825 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 J24 mock treatment 1.07976617E8 2630000.0 0.23 1.01120134E8 2660000.0 0.23 0.3252 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K01 compound treatment 1.17753367E8 1.24E7 1.07 9.9768899E7 1310000.0 0.11 0.8387 0.7785 1965245 CMLD1_000211 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K02 compound treatment 1.0954725E8 4200000.0 0.36 9.3396156E7 -5060000.0 -0.44 -0.0568 -0.0993 1965246 CMLD1_000212 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K03 compound treatment 1.16977517E8 1.16E7 1.0 1.03531302E8 5070000.0 0.44 1.0242 0.9327 1965247 CMLD1_000213 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K04 compound treatment 1.02688102E8 -2660000.0 -0.23 9.459121E7 -3870000.0 -0.34 -0.4018 -0.9823 1965248 CMLD1_000214 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K05 compound treatment 1.08027455E8 2680000.0 0.23 9.5189065E7 -3270000.0 -0.29 -0.0387 -0.1052 1965249 CMLD1_000215 CCCC=C(CCC)[C@@H](NC(=O)C(C)(C)C)c1ccc(cc1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K06 compound treatment 9.0458331E7 -1.49E7 -1.29 8.1351644E7 -1.71E7 -1.5 -1.968 -0.9971 1965250 CMLD1_000216 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K07 compound treatment 1.17436245E8 1.21E7 1.04 1.04836684E8 6380000.0 0.56 1.133 0.957 1965251 CMLD1_000217 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K08 compound treatment 9.4181815E7 -1.12E7 -0.96 8.2946046E7 -1.55E7 -1.36 -1.642 -0.986 1965252 CMLD1_000218 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K09 compound treatment 9.6308666E7 -9040000.0 -0.78 8.8921434E7 -9530000.0 -0.83 -1.1423 -0.9995 1965253 CMLD1_000219 CCCC=C(CCC)[C@@H](NC(=O)Cc1ccccc1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K10 compound treatment 8.9411549E7 -1.59E7 -1.38 8.1496126E7 -1.7E7 -1.48 -2.023 -0.9993 1965254 CMLD1_000220 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K11 compound treatment 1.08763046E8 3410000.0 0.29 9.7245911E7 -1210000.0 -0.11 0.1335 0.4263 1965255 CMLD1_000221 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K12 compound treatment 7.5604598E7 -2.97E7 -2.57 7.4260355E7 -2.42E7 -2.12 -3.3141 -0.9954 1965256 CMLD1_000222 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K13 compound treatment 1.17168181E8 1.18E7 1.02 9.9024903E7 568000.0 0.05 0.7569 0.7407 1965257 CMLD1_000223 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K14 compound treatment 9.5342906E7 -1.0E7 -0.86 9.1511492E7 -6940000.0 -0.61 -1.041 -0.9852 1965258 CMLD1_000224 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K15 compound treatment 1.17436178E8 1.21E7 1.04 1.0437253E8 5920000.0 0.52 1.1042 0.9477 1965259 CMLD1_000225 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K16 compound treatment 9.9446945E7 -5900000.0 -0.51 9.3499037E7 -4960000.0 -0.43 -0.6673 -0.9968 1965260 CMLD1_000226 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K17 compound treatment 9.612837E7 -9220000.0 -0.8 9.4538334E7 -3920000.0 -0.34 -0.8057 -0.9291 1965261 CMLD1_000227 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccco2)[C@]3(C)C[C@H]3C4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K18 compound treatment 1.01170196E8 -4180000.0 -0.36 9.412955E7 -4330000.0 -0.38 -0.5231 -0.9997 1965262 CMLD1_000228 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K19 compound treatment 1.07779578E8 2430000.0 0.21 9.7763211E7 -693000.0 -0.06 0.1055 0.4829 1965263 CMLD1_000229 CCCC[C@@H]1C[C@H]1[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K20 compound treatment 9.3319721E7 -1.2E7 -1.04 8.7316873E7 -1.11E7 -0.97 -1.4241 -0.9995 1965264 CMLD1_000230 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K21 compound treatment 1.04818176E8 -532000.0 -0.05 9.9029593E7 573000.0 0.05 0.003 0.0435 1965265 CMLD1_000231 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K22 mock treatment 9.8421064E7 -6930000.0 -0.6 9.6520361E7 -1940000.0 -0.17 -0.543 -0.873 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K23 mock treatment 1.08009453E8 2660000.0 0.23 1.0020112E8 1740000.0 0.15 0.2704 0.9803 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 K24 mock treatment 1.06804928E8 1450000.0 0.13 9.9857549E7 1400000.0 0.12 0.1755 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L01 compound treatment 1.09248772E8 3900000.0 0.34 9.9894278E7 1440000.0 0.13 0.3271 0.9099 1965266 CMLD1_000232 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L02 compound treatment 9.8863471E7 -6490000.0 -0.56 9.0736997E7 -7720000.0 -0.68 -0.8739 -0.9957 1965267 CMLD1_000233 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L03 compound treatment 1.00587978E8 -4760000.0 -0.41 9.5484389E7 -2970000.0 -0.26 -0.4748 -0.9756 1965268 CMLD1_000234 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L04 compound treatment 1.16054165E8 1.07E7 0.92 1.04783834E8 6330000.0 0.55 1.0453 0.97 1965269 CMLD1_000235 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@H](CC32CC3)c4cccc(OC)c4)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L05 compound treatment 9.1982772E7 -1.34E7 -1.15 9.1668964E7 -6790000.0 -0.59 -1.2365 -0.9523 1965270 CMLD1_000236 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7cc8ccccc8[nH]7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L06 compound treatment 1.07430963E8 2080000.0 0.18 9.0877878E7 -7580000.0 -0.66 -0.3419 -0.4976 1965271 CMLD1_000237 C=C(CC1(CNP(=O)(c2ccccc2)c3ccccc3)CC1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L07 compound treatment 9.7525313E7 -7830000.0 -0.68 9.1259556E7 -7200000.0 -0.63 -0.9233 -0.9994 1965272 CMLD1_000238 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L08 compound treatment 8.7362622E7 -1.8E7 -1.55 8.6262418E7 -1.22E7 -1.07 -1.8532 -0.9832 1965273 CMLD1_000239 CCCC1(NCC2=C(C(=O)C(C)C2=C1)c3ccccc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L09 compound treatment 1.00329146E8 -5020000.0 -0.43 9.6445902E7 -2010000.0 -0.18 -0.4311 -0.9211 1965274 CMLD1_000240 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L10 compound treatment 8.6562272E7 -1.88E7 -1.62 8.2365662E7 -1.61E7 -1.41 -2.1432 -0.9975 1965275 CMLD1_000241 COC(=O)C1(CC(C)C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L11 compound treatment 9.6098932E7 -9250000.0 -0.8 9.3402679E7 -5050000.0 -0.44 -0.8778 -0.9611 1965276 CMLD1_000242 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L12 compound treatment 9.0952572E7 -1.44E7 -1.24 8.5989405E7 -1.25E7 -1.09 -1.6509 -0.9979 1965277 CMLD1_000243 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cc(F)cc(F)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L13 compound treatment 9.3578861E7 -1.18E7 -1.02 8.6183796E7 -1.23E7 -1.07 -1.4784 -0.9996 1965278 CMLD1_000244 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L14 compound treatment 9.1744915E7 -1.36E7 -1.18 8.8329633E7 -1.01E7 -0.89 -1.4576 -0.9903 1965279 CMLD1_000245 CC[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L15 compound treatment 9.9372484E7 -5980000.0 -0.52 9.3237846E7 -5220000.0 -0.46 -0.688 -0.9981 1965280 CMLD1_000246 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L16 compound treatment 9.8543323E7 -6810000.0 -0.59 9.3997335E7 -4460000.0 -0.39 -0.6917 -0.9802 1965281 CMLD1_000247 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccccc6)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L17 compound treatment 9.9535368E7 -5820000.0 -0.5 9.7751077E7 -705000.0 -0.06 -0.3988 -0.7881 1965282 CMLD1_000248 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSC(=N)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L18 compound treatment 9.8007524E7 -7340000.0 -0.63 9.0239901E7 -8220000.0 -0.72 -0.9569 -0.998 1965079 CMLD1_000249 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L19 compound treatment 9.859165E7 -6760000.0 -0.58 9.7014347E7 -1440000.0 -0.13 -0.502 -0.8406 1965283 CMLD1_000250 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L20 compound treatment 1.05429727E8 79300.0 0.01 9.7518678E7 -938000.0 -0.08 -0.0532 -0.6458 1965284 CMLD1_000251 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L21 compound treatment 9.8818208E7 -6530000.0 -0.56 9.7263118E7 -1190000.0 -0.1 -0.4728 -0.824 1965285 CMLD1_000252 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L22 mock treatment 1.0854198E8 3190000.0 0.28 9.751818E7 -938000.0 -0.08 0.1369 0.4758 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L23 mock treatment 1.06046137E8 696000.0 0.06 1.05144229E8 6690000.0 0.59 0.4564 0.7756 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 L24 mock treatment 1.08358196E8 3010000.0 0.26 9.8058757E7 -398000.0 -0.03 0.1591 0.607 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M01 compound treatment 1.1316226E8 7810000.0 0.67 1.01172641E8 2720000.0 0.24 0.6452 0.9019 1965286 CMLD1_000253 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M02 compound treatment 1.04459317E8 -891000.0 -0.08 8.5669849E7 -1.28E7 -1.12 -0.8457 -0.754 1965287 CMLD1_000254 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M03 compound treatment 1.17517977E8 1.22E7 1.05 1.04890744E8 6430000.0 0.56 1.1413 0.9572 1965288 CMLD1_000255 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M04 compound treatment 1.06109079E8 759000.0 0.07 9.1401071E7 -7060000.0 -0.62 -0.3903 -0.6285 1965289 CMLD1_000256 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(C)onc7c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M05 compound treatment 1.01523393E8 -3830000.0 -0.33 9.5152241E7 -3300000.0 -0.29 -0.4382 -0.9978 1965290 CMLD1_000257 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M06 compound treatment 1.08872435E8 3520000.0 0.3 8.9938133E7 -8520000.0 -0.75 -0.312 -0.3875 1965090 CMLD1_000258 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M07 compound treatment 1.06955143E8 1600000.0 0.14 1.02625737E8 4170000.0 0.36 0.356 0.9121 1965291 CMLD1_000259 CCCCC=C[C@@H](NC(=O)c1ccco1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M08 compound treatment 8.7141628E7 -1.82E7 -1.57 7.2378889E7 -2.61E7 -2.28 -2.7259 -0.9835 1965292 CMLD1_000260 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M09 compound treatment 1.13015994E8 7670000.0 0.66 1.0510168E8 6650000.0 0.58 0.8794 0.9979 1965293 CMLD1_000261 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)OCc2ccccc2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M10 compound treatment 9.0604791E7 -1.47E7 -1.27 8.1082789E7 -1.74E7 -1.52 -1.9757 -0.9961 1965294 CMLD1_000262 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCCNc6ccc(cc6Cl)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M11 compound treatment 1.05603704E8 253000.0 0.02 8.6394182E7 -1.21E7 -1.06 -0.731 -0.6923 1965295 CMLD1_000263 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M12 compound treatment 8.7577351E7 -1.78E7 -1.54 8.2151006E7 -1.63E7 -1.43 -2.0945 -0.9993 1965296 CMLD1_000264 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M13 compound treatment 8.9667379E7 -1.57E7 -1.35 7.7692662E7 -2.08E7 -1.82 -2.2428 -0.9895 1965297 CMLD1_000265 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M14 compound treatment 9.2834292E7 -1.25E7 -1.08 8.263684E7 -1.58E7 -1.38 -1.7434 -0.9925 1965298 CMLD1_000266 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M15 compound treatment 9.6806059E7 -8540000.0 -0.74 1.02831929E8 4380000.0 0.38 -0.2511 -0.302 1965299 CMLD1_000267 CCCC[C@@H]1C[C@H]1[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M16 compound treatment 1.00467697E8 -4880000.0 -0.42 8.6914536E7 -1.15E7 -1.01 -1.0125 -0.925 1965300 CMLD1_000268 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(O)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M17 compound treatment 9.8727938E7 -6620000.0 -0.57 1.02549781E8 4090000.0 0.36 -0.1512 -0.224 1965301 CMLD1_000269 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(Cl)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M18 compound treatment 9.9887281E7 -5460000.0 -0.47 8.4712909E7 -1.37E7 -1.2 -1.1842 -0.9165 1965302 CMLD1_000270 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M19 compound treatment 1.0708009E8 1730000.0 0.15 9.7354321E7 -1100000.0 -0.1 0.0374 0.2105 1965303 CMLD1_000271 CCCC=C(CCC)[C@@H](NC(=O)Oc1ccc(F)cc1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M20 compound treatment 1.02685537E8 -2660000.0 -0.23 9.7349548E7 -1110000.0 -0.1 -0.2313 -0.926 1965304 CMLD1_000272 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M21 mock treatment 9.9643302E7 -5710000.0 -0.49 9.7206334E7 -1250000.0 -0.11 -0.4259 -0.8435 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M22 mock treatment 1.06028398E8 678000.0 0.06 9.9057871E7 601000.0 0.05 0.0786 0.9986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M23 mock treatment 1.08954712E8 3600000.0 0.31 1.02447779E8 3990000.0 0.35 0.4671 0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 M24 mock treatment 1.04641489E8 -709000.0 -0.06 9.2947672E7 -5510000.0 -0.48 -0.3842 -0.7906 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N01 compound treatment 1.10628999E8 5280000.0 0.46 1.03302129E8 4850000.0 0.42 0.6223 0.9993 1965305 CMLD1_000273 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N02 compound treatment 9.6773993E7 -8580000.0 -0.74 8.4612609E7 -1.38E7 -1.21 -1.3805 -0.9721 1965306 CMLD1_000274 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N03 compound treatment 7.8381846E7 -2.7E7 -2.33 6.9339967E7 -2.91E7 -2.55 -3.4489 -0.999 1965307 CMLD1_000275 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N04 compound treatment 1.09896634E8 4550000.0 0.39 1.05164778E8 6710000.0 0.59 0.6928 0.9809 1965308 CMLD1_000276 COC(=O)c1ccc(C#CC(NP(=O)(c2ccccc2)c3ccccc3)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N05 compound treatment 9.5166251E7 -1.02E7 -0.88 8.5883557E7 -1.26E7 -1.1 -1.4001 -0.9938 1965309 CMLD1_000277 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N06 compound treatment 1.04663939E8 -686000.0 -0.06 9.5219343E7 -3240000.0 -0.28 -0.2423 -0.837 1965310 CMLD1_000278 O=P(NCC1(CC2(CO2)c3ccccc3)CC1)(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N07 compound treatment 1.01910021E8 -3440000.0 -0.3 9.2488949E7 -5970000.0 -0.52 -0.5794 -0.9643 1965311 CMLD1_000279 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N08 compound treatment 9.2761272E7 -1.26E7 -1.09 8.9161788E7 -9290000.0 -0.81 -1.3441 -0.9898 1965312 CMLD1_000280 CCCCCC1=C2CNC(CCC)(C=C2C(C)C1=O)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N09 compound treatment 1.04363847E8 -987000.0 -0.09 9.8976059E7 520000.0 0.05 -0.0281 -0.2909 1965313 CMLD1_000281 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CCOCC7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N10 compound treatment 9.8226952E7 -7120000.0 -0.62 8.6151996E7 -1.23E7 -1.08 -1.1965 -0.9648 1965314 CMLD1_000282 CCCCCC1=C2CNC(CC(C)C)(C=C2C(C)C1=O)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N11 compound treatment 7.1370721E7 -3.4E7 -2.93 9.8275827E7 -181000.0 -0.02 -2.0865 -0.7109 1965315 CMLD1_000283 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N12 compound treatment 9.340196E7 -1.19E7 -1.03 9.0021748E7 -8430000.0 -0.74 -1.2517 -0.9865 1965316 CMLD1_000284 COC1OC[C@]2(C)[C@@H]3[C@H]1CCC4C(CO)C(CO)[C@@H](C)C(=C43)CN2C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N13 compound treatment 1.01920281E8 -3430000.0 -0.3 9.0622976E7 -7830000.0 -0.69 -0.6943 -0.9296 1965317 CMLD1_000285 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N14 compound treatment 9.0008379E7 -1.53E7 -1.33 9.2363133E7 -6090000.0 -0.53 -1.3141 -0.92 1965318 CMLD1_000286 CC[C@@H]1C(COC)C(COC)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N15 compound treatment 9.9975792E7 -5370000.0 -0.46 9.2356565E7 -6100000.0 -0.53 -0.7057 -0.9976 1965319 CMLD1_000287 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N16 compound treatment 9.8135404E7 -7220000.0 -0.62 8.5870672E7 -1.26E7 -1.1 -1.2195 -0.9636 1965320 CMLD1_000288 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccccc5)C=C21)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N17 compound treatment 9.5581136E7 -9770000.0 -0.84 9.5209057E7 -3250000.0 -0.28 -0.7976 -0.8958 1965321 CMLD1_000289 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N18 compound treatment 9.6695155E7 -8660000.0 -0.75 9.3890184E7 -4570000.0 -0.4 -0.8112 -0.957 1965322 CMLD1_000290 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N19 compound treatment 1.03839893E8 -1510000.0 -0.13 9.0902487E7 -7550000.0 -0.66 -0.5597 -0.8306 1965323 CMLD1_000291 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(O)cc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N20 compound treatment 9.5626287E7 -9720000.0 -0.84 9.731025E7 -1150000.0 -0.1 -0.6648 -0.786 1965324 CMLD1_000292 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N21 mock treatment 1.01868613E8 -3480000.0 -0.3 1.02166527E8 3710000.0 0.32 0.0169 0.0383 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N22 mock treatment 8.2528498E7 -2.28E7 -1.97 9.031048E7 -8150000.0 -0.71 -1.8979 -0.9054 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N23 mock treatment 1.05397212E8 46800.0 0.0 1.01534667E8 3080000.0 0.27 0.1934 0.7176 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 N24 mock treatment 1.08114405E8 2760000.0 0.24 1.02186513E8 3730000.0 0.33 0.3996 0.9882 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O01 compound treatment 1.09834608E8 4480000.0 0.39 9.8671053E7 215000.0 0.02 0.2872 0.7405 1965325 CMLD1_000293 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccc(cc1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O02 compound treatment 9.914705E7 -6200000.0 -0.54 8.5955332E7 -1.25E7 -1.09 -1.1525 -0.946 1965326 CMLD1_000294 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O03 compound treatment 1.17383504E8 1.2E7 1.04 1.05328039E8 6870000.0 0.6 1.1602 0.9662 1965327 CMLD1_000295 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O04 compound treatment 9.4871867E7 -1.05E7 -0.91 8.0258481E7 -1.82E7 -1.59 -1.7661 -0.9641 1965268 CMLD1_000296 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O05 compound treatment 1.18069572E8 1.27E7 1.1 1.05006251E8 6550000.0 0.57 1.1821 0.954 1965328 CMLD1_000297 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O06 compound treatment 1.04220112E8 -1130000.0 -0.1 8.9570492E7 -8890000.0 -0.78 -0.6189 -0.7897 1965329 CMLD1_000298 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O07 compound treatment 1.07475485E8 2130000.0 0.18 9.1178158E7 -7280000.0 -0.64 -0.3206 -0.4837 1965330 CMLD1_000299 CCCCC=C[C@@H](NC(=O)c1cccs1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O08 compound treatment 1.04108388E8 -1240000.0 -0.11 9.3437647E7 -5020000.0 -0.44 -0.3864 -0.8547 1965331 CMLD1_000300 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O09 compound treatment 1.13614705E8 8260000.0 0.71 9.7470727E7 -986000.0 -0.09 0.4437 0.6172 1965332 CMLD1_000301 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O10 compound treatment 8.3804222E7 -2.15E7 -1.86 7.3085398E7 -2.54E7 -2.22 -2.886 -0.9961 1965333 CMLD1_000302 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O11 compound treatment 9.7947264E7 -7400000.0 -0.64 8.9419459E7 -9040000.0 -0.79 -1.0114 -0.9944 1965334 CMLD1_000303 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O12 compound treatment 8.59765E7 -1.94E7 -1.67 7.1916502E7 -2.65E7 -2.32 -2.8257 -0.9871 1965335 CMLD1_000304 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O13 compound treatment 1.01004471E8 -4350000.0 -0.38 1.05064345E8 6610000.0 0.58 0.1435 0.2081 1965336 CMLD1_000305 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O14 compound treatment 3.6379936E7 -6.9E7 -5.96 3.6208206E7 -6.22E7 -5.45 -8.0645 -0.999 1965337 CMLD1_000306 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O15 compound treatment 1.06835326E8 1480000.0 0.13 9.9285587E7 829000.0 0.07 0.142 0.9636 1965338 CMLD1_000307 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O16 compound treatment 1.03519365E8 -1830000.0 -0.16 9.1626141E7 -6830000.0 -0.6 -0.5345 -0.8644 1965339 CMLD1_000308 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O17 compound treatment 1.10612547E8 5260000.0 0.45 9.736068E7 -1100000.0 -0.1 0.2536 0.5459 1965340 CMLD1_000309 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O18 compound treatment 1.02672404E8 -2680000.0 -0.23 9.4395645E7 -4060000.0 -0.36 -0.4149 -0.9784 1965341 CMLD1_000310 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O19 compound treatment 1.18228213E8 1.29E7 1.11 1.04995362E8 6540000.0 0.57 1.1912 0.9523 1965342 CMLD1_000311 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O20 compound treatment 6.5664456E7 -3.97E7 -3.43 5.3697243E7 -4.48E7 -3.92 -5.1937 -0.9978 1965343 CMLD1_000312 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O21 mock treatment 1.16284375E8 1.09E7 0.94 1.05492349E8 7040000.0 0.62 1.1032 0.9785 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O22 mock treatment 1.01943913E8 -3410000.0 -0.29 9.8982063E7 526000.0 0.05 -0.1755 -0.5894 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O23 mock treatment 1.08484441E8 3130000.0 0.27 1.00027361E8 1570000.0 0.14 0.2886 0.9507 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 O24 mock treatment 1.09800471E8 4450000.0 0.38 1.02396459E8 3940000.0 0.34 0.5156 0.9985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P01 compound treatment 1.01927343E8 -3420000.0 -0.3 9.8761554E7 305000.0 0.03 -0.1902 -0.6406 1965344 CMLD1_000313 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P02 compound treatment 8.6808191E7 -1.85E7 -1.6 9.4871464E7 -3580000.0 -0.31 -1.3543 -0.8299 1965345 CMLD1_000314 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P03 compound treatment 8.6571861E7 -1.88E7 -1.62 9.7945133E7 -511000.0 -0.04 -1.1785 -0.7263 1965346 CMLD1_000315 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P04 compound treatment 9.1513742E7 -1.38E7 -1.2 9.6909619E7 -1550000.0 -0.14 -0.9408 -0.7822 1965347 CMLD1_000316 COC(=O)c1ccc(cc1)C23CC3(C2)C(NP(=O)(c4ccccc4)c5ccccc5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P05 compound treatment 1.05822669E8 472000.0 0.04 9.3673702E7 -4780000.0 -0.42 -0.2671 -0.6352 1965348 CMLD1_000317 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P06 compound treatment 1.01859477E8 -3490000.0 -0.3 9.413532E7 -4320000.0 -0.38 -0.4806 -0.9937 1965349 CMLD1_000318 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P07 compound treatment 1.1130683E8 5960000.0 0.51 9.9377226E7 921000.0 0.08 0.4208 0.808 1965350 CMLD1_000319 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P08 compound treatment 1.0032835E8 -5020000.0 -0.43 8.9519895E7 -8940000.0 -0.78 -0.8598 -0.9613 1965351 CMLD1_000320 COC(=O)C1(Cc2ccccc2)NCC3=C(C)C(=O)C(C)C3=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P09 compound treatment 9.903576E7 -6310000.0 -0.55 9.0279826E7 -8180000.0 -0.72 -0.8917 -0.991 1965352 CMLD1_000321 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P10 compound treatment 9.8542704E7 -6810000.0 -0.59 8.8429341E7 -1.0E7 -0.88 -1.0363 -0.981 1965353 CMLD1_000322 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P11 compound treatment 9.9216931E7 -6130000.0 -0.53 9.2948495E7 -5510000.0 -0.48 -0.7155 -0.9989 1965354 CMLD1_000323 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P12 compound treatment 1.00116962E8 -5230000.0 -0.45 9.2098081E7 -6360000.0 -0.56 -0.7131 -0.9947 1965355 CMLD1_000324 CC[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OC)OC[C@]4(C)[C@H]3C2=C1CN4C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P13 compound treatment 7.9228247E7 -2.61E7 -2.26 8.1947276E7 -1.65E7 -1.44 -2.6171 -0.9768 1965356 CMLD1_000325 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P14 compound treatment 1.01895478E8 -3450000.0 -0.3 8.9097526E7 -9360000.0 -0.82 -0.7902 -0.9064 1965357 CMLD1_000326 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(OC)cc5)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P15 compound treatment 1.03000291E8 -2350000.0 -0.2 9.640154E7 -2050000.0 -0.18 -0.2707 -0.9982 1965358 CMLD1_000327 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P16 compound treatment 9.1631013E7 -1.37E7 -1.18 8.3992097E7 -1.45E7 -1.27 -1.733 -0.9995 1965359 CMLD1_000328 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)cc7COCOc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P17 compound treatment 2.0836002E7 -8.45E7 -7.3 2.0608426E7 -7.78E7 -6.81 -9.9792 -0.9994 1965360 CMLD1_000329 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P18 compound treatment 1.02691082E8 -2660000.0 -0.23 9.4003033E7 -4450000.0 -0.39 -0.438 -0.9682 1965361 CMLD1_000330 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P19 compound treatment 1.05835603E8 485000.0 0.04 9.4676893E7 -3780000.0 -0.33 -0.2043 -0.6126 1965362 CMLD1_000331 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P20 compound treatment 1.05066077E8 -284000.0 -0.02 9.5789854E7 -2670000.0 -0.23 -0.1824 -0.7772 1965363 CMLD1_000332 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P21 mock treatment 1.08973415E8 3620000.0 0.31 1.03664952E8 5210000.0 0.46 0.5436 0.9832 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P22 mock treatment 1.06672949E8 1320000.0 0.11 9.8727936E7 272000.0 0.02 0.0976 0.8363 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P23 mock treatment 1.11096528E8 5750000.0 0.5 1.01484862E8 3030000.0 0.27 0.5384 0.9568 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1462 P24 mock treatment 1.13997372E8 8650000.0 0.75 1.02072755E8 3620000.0 0.32 0.7519 0.927 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A01 compound treatment 1.17705855E8 7400000.0 0.64 1.0796454E8 7570000.0 0.66 0.9205 0.9998 2065621 ICCB6_000001 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A02 compound treatment 1.0403977E8 -6260000.0 -0.54 9.8646935E7 -1750000.0 -0.15 -0.4907 -0.8728 2065622 ICCB6_000002 OCCCCCCCCCc1ccc(C=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A03 compound treatment 9.832074E7 -1.2E7 -1.04 9.5266726E7 -5130000.0 -0.45 -1.0492 -0.93 2065623 ICCB6_000003 CC1(C)OC(=O)C=C(CC(O)c2ccccc2)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A04 compound treatment 9.1378508E7 -1.89E7 -1.63 8.4112354E7 -1.63E7 -1.42 -2.1635 -0.9977 2065624 ICCB6_000004 CO[C@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc3ccccc3)[C@@H]1OCCCc4ccc(C=O)o4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A05 compound treatment 7.0391844E7 -3.99E7 -3.45 9.0593007E7 -9800000.0 -0.86 -3.0442 -0.8569 2065625 ICCB6_000005 Clc1ccccc1C(CC(=O)c2ccccc2)C(=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A06 compound treatment 9.5524772E7 -1.48E7 -1.28 9.1344027E7 -9050000.0 -0.79 -1.4627 -0.9737 2065626 ICCB6_000006 OCCCCCCCCCCc1ccc(C=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A07 compound treatment 8.2289678E7 -2.8E7 -2.42 8.3783332E7 -1.66E7 -1.45 -2.7389 -0.9703 2065627 ICCB6_000007 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A08 compound treatment 9.6619159E7 -1.37E7 -1.18 8.6144227E7 -1.43E7 -1.25 -1.7177 -0.9996 2065628 ICCB6_000008 OC[C@H](COCCCc1ccc(C=O)o1)OCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A09 compound treatment 8.7839579E7 -2.25E7 -1.94 7.8587245E7 -2.18E7 -1.91 -2.7215 -1.0 2065629 ICCB6_000009 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A10 compound treatment 8.3650755E7 -2.67E7 -2.3 8.3266418E7 -1.71E7 -1.5 -2.6878 -0.9784 2065630 ICCB6_000010 OCCOCCCc1ccc(C=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A11 compound treatment 8.9888052E7 -2.04E7 -1.76 7.4443808E7 -2.6E7 -2.27 -2.8528 -0.9922 2065631 ICCB6_000011 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A12 compound treatment 8.8313361E7 -2.2E7 -1.9 8.2191535E7 -1.82E7 -1.59 -2.4696 -0.9962 2065632 ICCB6_000012 OCc1ccc(CCc2ccc(C=O)o2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A13 compound treatment 8.810628E7 -2.22E7 -1.92 8.3465948E7 -1.69E7 -1.48 -2.4033 -0.9919 2065633 ICCB6_000013 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A14 compound treatment 8.8758158E7 -2.15E7 -1.86 8.296591E7 -1.74E7 -1.53 -2.3945 -0.9951 2065634 ICCB6_000014 OCCOCCOCCCc1ccc(C=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A15 compound treatment 8.1695479E7 -2.86E7 -2.47 7.9033011E7 -2.14E7 -1.87 -3.0692 -0.9905 ICCB6_000015 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A16 compound treatment 9.2266647E7 -1.8E7 -1.56 8.9069699E7 -1.13E7 -0.99 -1.8025 -0.9762 2065635 ICCB6_000016 OCC1CC2CCN1CC2CCc3ccc(C=O)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A17 compound treatment 8.9593745E7 -2.07E7 -1.79 8.8342481E7 -1.21E7 -1.05 -2.0107 -0.9683 1952805 ICCB6_000017 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A18 compound treatment 8.5675843E7 -2.46E7 -2.13 8.9365453E7 -1.1E7 -0.97 -2.1867 -0.9361 2065636 ICCB6_000018 OCCCCNC(=O)OCCCc1ccc(C=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A19 compound treatment 8.0820618E7 -2.95E7 -2.55 8.7204619E7 -1.32E7 -1.15 -2.6169 -0.936 1952839 ICCB6_000019 Oc1ccccc1C#CC#Cc2ccccc2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A20 compound treatment 7.878506E7 -3.15E7 -2.72 9.1275908E7 -9120000.0 -0.8 -2.4893 -0.8775 2065637 ICCB6_000020 OCCCCc1ccc(C=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A21 compound treatment 7.270524E7 -3.76E7 -3.25 8.7184289E7 -1.32E7 -1.16 -3.1138 -0.9033 1952635 ICCB6_000021 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A22 compound treatment 4.5921062E7 -6.44E7 -5.56 9.6569332E7 -3830000.0 -0.33 -4.1689 -0.7483 2065638 ICCB6_000022 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A23 mock treatment 9.0875869E7 -1.94E7 -1.68 9.4212838E7 -6180000.0 -0.54 -1.5691 -0.89 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 A24 mock treatment 1.02115555E8 -8190000.0 -0.71 9.8729056E7 -1670000.0 -0.15 -0.6032 -0.8353 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B01 compound treatment 1.1270574E8 2400000.0 0.21 1.03665203E8 3270000.0 0.29 0.3491 0.9875 2065621 ICCB6_000023 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B02 compound treatment 8.462217E7 -2.57E7 -2.22 8.5882046E7 -1.45E7 -1.27 -2.4666 -0.965 2065639 ICCB6_000024 OB1OC(COCc2ccccc2)CC=C1C(=C)CCCc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B03 compound treatment 9.4157375E7 -1.61E7 -1.39 8.7730384E7 -1.27E7 -1.11 -1.7699 -0.9935 2065640 ICCB6_000025 CC1(C)OC(=O)C=C(CC(O)C2CCCCC2)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B04 compound treatment 9.0129212E7 -2.02E7 -1.74 8.842705E7 -1.2E7 -1.05 -1.9728 -0.9703 2065641 ICCB6_000026 CC(C)C(=C)C1=CCC(COCc2ccccc2)OB1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B05 compound treatment 1.05723506E8 -4580000.0 -0.4 1.04434999E8 4040000.0 0.35 -0.0297 -0.056 2065642 ICCB6_000027 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B06 compound treatment 9.0376768E7 -1.99E7 -1.72 8.1978528E7 -1.84E7 -1.61 -2.3567 -0.9995 2065643 ICCB6_000028 CCCC(=C)C1=CCC(COCc2ccccc2)OB1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B07 compound treatment 7.9171455E7 -3.11E7 -2.69 8.5708385E7 -1.47E7 -1.29 -2.8103 -0.9429 2065644 ICCB6_000029 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B08 compound treatment 9.3799436E7 -1.65E7 -1.43 8.4613448E7 -1.58E7 -1.38 -1.9846 -0.9999 2065645 ICCB6_000030 O[C@@H]([C@H](Oc1ccccc1)C=C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B09 compound treatment 8.9365036E7 -2.09E7 -1.81 8.3542825E7 -1.69E7 -1.47 -2.3217 -0.9949 2065646 ICCB6_000031 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B10 compound treatment 8.1434048E7 -2.89E7 -2.49 7.6545962E7 -2.38E7 -2.09 -3.2391 -0.9961 2065647 ICCB6_000032 O[C@H](COCc1ccccc1)[C@H](Oc2ccccc2)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B11 compound treatment 9.1789351E7 -1.85E7 -1.6 8.2825852E7 -1.76E7 -1.54 -2.218 -0.9998 2065648 ICCB6_000033 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B12 compound treatment 7.7874279E7 -3.24E7 -2.8 7.7144745E7 -2.32E7 -2.03 -3.4194 -0.9877 2065649 ICCB6_000034 CC(C)C(=C)C(=O)CCC(COCc1ccccc1)OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B13 compound treatment 8.7011023E7 -2.33E7 -2.01 8.3720075E7 -1.67E7 -1.46 -2.4545 -0.9876 2065650 ICCB6_000035 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B14 compound treatment 6.4089828E7 -4.62E7 -3.99 5.9474781E7 -4.09E7 -3.58 -5.3548 -0.9985 2065651 ICCB6_000036 CCCC(=C=CC[C@@H](OC(=O)Nc1ccc(Br)cc1)c2ccccc2)CCOC(=O)Nc3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B15 compound treatment 9.4850902E7 -1.55E7 -1.33 8.5477092E7 -1.49E7 -1.31 -1.867 -0.9999 1952458 ICCB6_000037 Fc1ccc(cc1Br)[C@@H]2C3=C(C[C@@H]4C2=CCn5n4c(=O)n(c6ccccc6)c5=O)C(=O)OC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B16 compound treatment 8.5200115E7 -2.51E7 -2.17 8.0447562E7 -1.99E7 -1.75 -2.7676 -0.9942 2065652 ICCB6_000038 CC(C)C(=C=CC[C@H](COCc1ccccc1)OC(=O)c2ccc(Br)cc2)CCOC(=O)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B17 compound treatment 9.3882152E7 -1.64E7 -1.42 9.2087494E7 -8310000.0 -0.73 -1.517 -0.9518 1952808 ICCB6_000039 CCCCCc1cc2ccccc2o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B18 compound treatment 9.0492796E7 -1.98E7 -1.71 8.0365345E7 -2.0E7 -1.75 -2.4495 -0.9999 2065653 ICCB6_000040 CC1(C)OC[C@@H](C=C)[C@H](CCc2ccccc2)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B19 compound treatment 9.3639326E7 -1.67E7 -1.44 9.3719779E7 -6670000.0 -0.58 -1.4309 -0.9211 1952842 ICCB6_000041 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B20 compound treatment 9.2848029E7 -1.75E7 -1.51 8.8751884E7 -1.16E7 -1.02 -1.7866 -0.9818 2065654 ICCB6_000042 CCC[C@@]1(CCO[Si](c2ccccc2)(c3ccccc3)C(C)(C)C)O[C@@H](Cc4ccccc4)CC=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B21 compound treatment 9.6344949E7 -1.4E7 -1.21 8.6526826E7 -1.39E7 -1.21 -1.7107 -1.0 1952636 ICCB6_000043 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B22 compound treatment 9.2730582E7 -1.76E7 -1.52 8.3642381E7 -1.68E7 -1.47 -2.11 -0.9998 3056822 ICCB6_000044 CC(C)[Si](OC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)c4ccccc4C3=O)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B23 mock treatment 1.12196043E8 1890000.0 0.16 9.9071846E7 -1320000.0 -0.12 0.0337 0.1682 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 B24 mock treatment 1.08796344E8 -1510000.0 -0.13 1.03041368E8 2650000.0 0.23 0.0717 0.2698 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C01 compound treatment 1.07123395E8 -3180000.0 -0.27 9.9059702E7 -1330000.0 -0.12 -0.2769 -0.9274 2065655 ICCB6_000045 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(C)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C02 compound treatment 9.7833928E7 -1.25E7 -1.08 9.1103797E7 -9290000.0 -0.81 -1.3366 -0.9904 2065656 ICCB6_000046 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C03 compound treatment 9.6744452E7 -1.36E7 -1.17 8.4090385E7 -1.63E7 -1.43 -1.8371 -0.9952 2065657 ICCB6_000047 COC(=O)c1cn2c(c1C(=O)OC)c(=O)n(C)c3ccccc32 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C04 compound treatment 9.2601923E7 -1.77E7 -1.53 8.9794282E7 -1.06E7 -0.93 -1.7371 -0.9713 2065658 ICCB6_000048 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@H](COC2=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C05 compound treatment 1.11866874E8 1560000.0 0.13 9.8522971E7 -1870000.0 -0.16 -0.0204 -0.096 2065659 ICCB6_000049 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3Cl)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C06 compound treatment 9.6030812E7 -1.43E7 -1.23 9.0071146E7 -1.03E7 -0.9 -1.5106 -0.9883 2065660 ICCB6_000050 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C07 compound treatment 8.7968928E7 -2.23E7 -1.93 7.8375067E7 -2.2E7 -1.93 -2.7268 -1.0 2065661 ICCB6_000051 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)CCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C08 compound treatment 9.1121666E7 -1.92E7 -1.66 8.5348461E7 -1.5E7 -1.32 -2.1027 -0.9935 2065662 ICCB6_000052 CC(C)[C@@H]1N(C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2)C(=O)OC1(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C09 compound treatment 8.7040778E7 -2.33E7 -2.01 8.4528492E7 -1.59E7 -1.39 -2.4027 -0.9837 2065663 ICCB6_000053 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C10 compound treatment 8.4592828E7 -2.57E7 -2.22 7.8611554E7 -2.18E7 -1.91 -2.9183 -0.9971 2065664 ICCB6_000054 COC(=O)[C@H](Cc1ccccc1)NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C11 compound treatment 9.1373395E7 -1.89E7 -1.64 7.8873948E7 -2.15E7 -1.88 -2.488 -0.9975 2065665 ICCB6_000055 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C12 compound treatment 7.9067733E7 -3.12E7 -2.7 7.9444654E7 -2.09E7 -1.83 -3.2042 -0.9823 2065666 ICCB6_000056 CCc1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C13 compound treatment 8.6662606E7 -2.36E7 -2.04 8.0627334E7 -1.98E7 -1.73 -2.6672 -0.9966 1065064 ICCB6_000057 [O-][N+](=O)c1ccc(CBr)c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C14 compound treatment 8.5098789E7 -2.52E7 -2.18 7.675066E7 -2.36E7 -2.07 -3.0026 -0.9997 2065667 ICCB6_000058 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(Oc3ccccc3)cc2)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C15 compound treatment 8.8921707E7 -2.14E7 -1.85 7.4522056E7 -2.59E7 -2.26 -2.907 -0.9949 1952482 ICCB6_000059 Fc1ccc(cc1Br)[C@H]2C3=CC[C@H]4[C@@H]([C@@H]3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C16 compound treatment 8.5502612E7 -2.48E7 -2.14 7.8929731E7 -2.15E7 -1.88 -2.8431 -0.9979 2065668 ICCB6_000060 COc1cccc(C)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C17 compound treatment 9.1152242E7 -1.92E7 -1.65 8.4307167E7 -1.61E7 -1.41 -2.1653 -0.9968 1952809 ICCB6_000061 CC(=O)Oc1ccccc1C#Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C18 compound treatment 8.8248858E7 -2.21E7 -1.9 8.2600738E7 -1.78E7 -1.56 -2.4482 -0.995 2065669 ICCB6_000062 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(C#N)cc2)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C19 compound treatment 8.4717184E7 -2.56E7 -2.21 9.5132098E7 -5260000.0 -0.46 -1.8884 -0.8365 1952773 ICCB6_000063 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C20 compound treatment 8.6117968E7 -2.42E7 -2.09 9.3027436E7 -7370000.0 -0.64 -1.9331 -0.8842 2065670 ICCB6_000064 CCOC(=O)CNC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C21 compound treatment 4.6930047E7 -6.34E7 -5.47 6.8857255E7 -3.15E7 -2.76 -5.8222 -0.9497 1952585 ICCB6_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C22 compound treatment 3.8628438E7 -7.17E7 -6.19 8.9103902E7 -1.13E7 -0.99 -5.0763 -0.8097 2065671 ICCB6_000066 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2F)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C23 mock treatment 7.9783166E7 -3.05E7 -2.64 9.697141E7 -3420000.0 -0.3 -2.0759 -0.7824 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 C24 mock treatment 1.14076721E8 3770000.0 0.33 1.02445607E8 2050000.0 0.18 0.3573 0.9605 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D01 compound treatment 1.13713481E8 3410000.0 0.29 9.2362067E7 -8030000.0 -0.7 -0.2889 -0.379 2065672 ICCB6_000067 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D02 compound treatment 9.7197852E7 -1.31E7 -1.13 9.4991365E7 -5400000.0 -0.47 -1.1348 -0.925 2065673 ICCB6_000068 CC(C)[Si](OC[C@@H]1CC=C(C)B(O)O1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D03 compound treatment 7.7203318E7 -3.31E7 -2.86 7.7669983E7 -2.27E7 -1.99 -3.4279 -0.9843 2065674 ICCB6_000069 CCOC(=O)C1[C@H](CCc2ccccc2)O[C@H](CCc3ccccc3)CC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D04 compound treatment 9.2851854E7 -1.75E7 -1.51 8.0139265E7 -2.03E7 -1.77 -2.3194 -0.9967 2065675 ICCB6_000070 CC(C)[Si](OC[C@H]1OB(O)CC=C1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D05 compound treatment 1.06266513E8 -4040000.0 -0.35 9.496519E7 -5430000.0 -0.48 -0.5826 -0.9884 2065676 ICCB6_000071 C[Si](C)(C(N[Si](=O)(=O)c1ccccc1)c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D06 compound treatment 9.1712324E7 -1.86E7 -1.61 8.6792235E7 -1.36E7 -1.19 -1.9773 -0.9891 2065677 ICCB6_000072 CC(C)[Si](OCC(O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D07 compound treatment 8.6727299E7 -2.36E7 -2.04 8.5818762E7 -1.46E7 -1.28 -2.342 -0.9746 2065678 ICCB6_000073 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D08 compound treatment 8.919246E7 -2.11E7 -1.82 7.759899E7 -2.28E7 -2.0 -2.7001 -0.999 2065679 ICCB6_000074 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D09 compound treatment 9.3180129E7 -1.71E7 -1.48 8.6433448E7 -1.4E7 -1.22 -1.9098 -0.9955 2065680 ICCB6_000075 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)CCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D10 compound treatment 9.1240647E7 -1.91E7 -1.65 8.3278365E7 -1.71E7 -1.5 -2.2235 -0.9989 2065681 ICCB6_000076 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D11 compound treatment 8.964143E7 -2.07E7 -1.78 8.5146999E7 -1.52E7 -1.33 -2.2056 -0.9897 2065682 ICCB6_000077 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D12 compound treatment 8.9332111E7 -2.1E7 -1.81 8.4598652E7 -1.58E7 -1.38 -2.2584 -0.9911 2065683 ICCB6_000078 CC(C)[Si](OCC(O)/C(=C\CO)/C)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D13 compound treatment 8.7971137E7 -2.23E7 -1.93 7.9309952E7 -2.11E7 -1.85 -2.6688 -0.9998 1952278 ICCB6_000079 COC(=O)c1nc(oc1C)C(NC(=O)CCc2cn(CC=C)c3ccccc23)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D14 compound treatment 8.7036933E7 -2.33E7 -2.01 8.0654431E7 -1.97E7 -1.73 -2.6426 -0.9972 2065684 ICCB6_000080 CC(C)[Si](OCC(O)/C=C\CO)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D15 compound treatment 8.7818839E7 -2.25E7 -1.94 7.6740003E7 -2.37E7 -2.07 -2.8371 -0.9995 2065685 ICCB6_000081 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D16 compound treatment 9.4379091E7 -1.59E7 -1.38 8.7336368E7 -1.31E7 -1.14 -1.7807 -0.9958 2065686 ICCB6_000082 CC(C)[Si](OC[C@@H](O)[C@@]1(C)OC(C)(C)OC1CO)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D17 compound treatment 9.1958176E7 -1.83E7 -1.58 8.4027328E7 -1.64E7 -1.43 -2.1333 -0.9987 1952811 ICCB6_000083 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D18 compound treatment 9.6835566E7 -1.35E7 -1.16 9.1066859E7 -9330000.0 -0.82 -1.3998 -0.985 2065687 ICCB6_000084 CC(C)[Si](OC[C@@H](O)[C@H]1OC(C)(C)OC1CO)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D19 compound treatment 1.00273177E8 -1.0E7 -0.87 9.4653829E7 -5740000.0 -0.5 -0.9679 -0.9664 1952780 ICCB6_000085 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D20 compound treatment 1.02152384E8 -8150000.0 -0.7 8.6096324E7 -1.43E7 -1.25 -1.3827 -0.963 2065688 ICCB6_000086 CC1(C)OC(CO)[C@H](O1)[C@H](O)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D21 compound treatment 1.07129432E8 -3170000.0 -0.27 9.1899689E7 -8490000.0 -0.74 -0.7196 -0.9081 1952670 ICCB6_000087 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D22 compound treatment 1.07427348E8 -2880000.0 -0.25 9.4088427E7 -6310000.0 -0.55 -0.566 -0.9351 2065689 ICCB6_000088 C/C(=C/CO)/[C@H](O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D23 mock treatment 1.00133326E8 -1.02E7 -0.88 9.8627126E7 -1770000.0 -0.15 -0.7306 -0.819 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 D24 mock treatment 1.11454976E8 1150000.0 0.1 9.2876635E7 -7520000.0 -0.66 -0.395 -0.5935 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E01 compound treatment 1.04659973E8 -5640000.0 -0.49 9.9477372E7 -917000.0 -0.08 -0.4015 -0.8126 2065690 ICCB6_000089 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)c(Cl)c4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E02 compound treatment 9.6795733E7 -1.35E7 -1.17 8.320892E7 -1.72E7 -1.5 -1.8885 -0.9921 2065691 ICCB6_000090 COc1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E03 compound treatment 7.3762894E7 -3.65E7 -3.16 6.1335842E7 -3.91E7 -3.42 -4.6489 -0.9992 2065692 ICCB6_000091 CCOC(=O)C1[C@@H](O[C@@H](CC1=O)c2ccccc2)C3CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E04 compound treatment 9.7940395E7 -1.24E7 -1.07 9.1063048E7 -9330000.0 -0.82 -1.3326 -0.9912 2065693 ICCB6_000092 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](O)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E05 compound treatment 1.15845613E8 5540000.0 0.48 1.07704004E8 7310000.0 0.64 0.7908 0.9898 2065694 ICCB6_000093 COc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)[Si](C)(C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E06 compound treatment 8.9067412E7 -2.12E7 -1.83 8.6190982E7 -1.42E7 -1.24 -2.176 -0.982 2065695 ICCB6_000094 CC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E07 compound treatment 9.3057645E7 -1.72E7 -1.49 8.8960206E7 -1.14E7 -1.0 -1.7609 -0.9813 2065696 ICCB6_000095 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E08 compound treatment 8.4464746E7 -2.58E7 -2.23 7.9271236E7 -2.11E7 -1.85 -2.8853 -0.9956 2065697 ICCB6_000096 CCOC(=O)c1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E09 compound treatment 8.4446391E7 -2.59E7 -2.23 8.3185801E7 -1.72E7 -1.51 -2.6442 -0.9816 2065698 ICCB6_000097 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E10 compound treatment 7.7711184E7 -3.26E7 -2.82 6.8253475E7 -3.21E7 -2.81 -3.9796 -1.0 2065699 ICCB6_000098 CCCCOC(=O)c1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E11 compound treatment 8.9400771E7 -2.09E7 -1.81 8.5026748E7 -1.54E7 -1.34 -2.2277 -0.9895 1952474 ICCB6_000099 OCCCCCNC(CCO)Cc1ccc2ccccc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E12 compound treatment 8.5786168E7 -2.45E7 -2.12 8.3118945E7 -1.73E7 -1.51 -2.5665 -0.9864 2065700 ICCB6_000100 COC(=O)[C@@H](NC(=O)OC/C=C/c1ccc(CCCCCCO)o1)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E13 compound treatment 9.3791221E7 -1.65E7 -1.43 8.6191682E7 -1.42E7 -1.24 -1.8875 -0.9977 1952280 ICCB6_000101 COC(=O)c1nc2oc1CC/C=C/Cn3cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C)c4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E14 compound treatment 8.7435768E7 -2.29E7 -1.98 8.3317266E7 -1.71E7 -1.49 -2.4535 -0.9905 2065701 ICCB6_000102 COc1cccc(Cl)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E15 compound treatment 7.9929127E7 -3.04E7 -2.62 7.1245484E7 -2.91E7 -2.55 -3.659 -0.9999 1952487 ICCB6_000103 Fc1ccc(cc1Br)[C@H]2C3=CCn4n(C3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)c(=O)n(c6ccccc6)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E16 compound treatment 8.9242829E7 -2.11E7 -1.82 8.9061217E7 -1.13E7 -0.99 -1.9877 -0.9593 2065702 ICCB6_000104 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E17 compound treatment 9.8795854E7 -1.15E7 -0.99 9.3710356E7 -6680000.0 -0.58 -1.1165 -0.9681 1952813 ICCB6_000105 OCCCC#Cc1cc(O)cc(Cl)c1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E18 compound treatment 1.00842358E8 -9460000.0 -0.82 9.8433125E7 -1960000.0 -0.17 -0.6993 -0.8374 2065703 ICCB6_000106 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](OC(=O)C)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E19 compound treatment 9.0086684E7 -2.02E7 -1.75 9.5986812E7 -4410000.0 -0.39 -1.5075 -0.843 3107406 ICCB6_000107 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E20 compound treatment 7.8932067E7 -3.14E7 -2.71 9.2725326E7 -7670000.0 -0.67 -2.3906 -0.8564 2065704 ICCB6_000108 C[C@@H]([C@H](OC(=O)C)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E21 compound treatment 6.9379555E7 -4.09E7 -3.53 9.5090304E7 -5300000.0 -0.46 -2.8277 -0.7932 ICCB6_000109 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E22 compound treatment 3.7639645E7 -7.27E7 -6.28 9.7293524E7 -3100000.0 -0.27 -4.6299 -0.737 2065705 ICCB6_000110 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2cccc(C)c2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E23 mock treatment 1.08096045E8 -2210000.0 -0.19 9.9571682E7 -823000.0 -0.07 -0.1858 -0.9113 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 E24 mock treatment 1.11371013E8 1070000.0 0.09 1.00739279E8 345000.0 0.03 0.0865 0.892 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F01 compound treatment 1.06263612E8 -4040000.0 -0.35 1.07062768E8 6670000.0 0.58 0.1659 0.244 2065706 ICCB6_000111 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(OC)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F02 compound treatment 9.5121226E7 -1.52E7 -1.31 9.8760363E7 -1630000.0 -0.14 -1.0284 -0.7796 2065707 ICCB6_000112 CC(C)[Si](OC[C@@H](O)C(C=C)C(O)c1ccccc1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F03 compound treatment 9.4002079E7 -1.63E7 -1.41 8.9786234E7 -1.06E7 -0.93 -1.6521 -0.9796 1009686 ICCB6_000113 O=C(CC(C(=O)c1ccccc1)c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F04 compound treatment 9.3666822E7 -1.66E7 -1.44 9.0879169E7 -9520000.0 -0.83 -1.605 -0.9663 2065708 ICCB6_000114 OC/C=C\C(O)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F05 compound treatment 9.1438488E7 -1.89E7 -1.63 9.166061E7 -8730000.0 -0.76 -1.6927 -0.9405 2065709 ICCB6_000115 CCCCCCCCNC(=O)CC[C@H]1O[C@H](O[C@H]2O[C@H](CCC(=O)NCCCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F06 compound treatment 9.4107606E7 -1.62E7 -1.4 8.5983431E7 -1.44E7 -1.26 -1.881 -0.9987 2065710 ICCB6_000116 CC1=C([C@H](O)C(C)(C)C)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F07 compound treatment 9.1673268E7 -1.86E7 -1.61 9.1680986E7 -8710000.0 -0.76 -1.6771 -0.9418 2065711 ICCB6_000117 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F08 compound treatment 8.6937151E7 -2.34E7 -2.02 8.7989586E7 -1.24E7 -1.09 -2.1948 -0.9577 2065712 ICCB6_000118 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F09 compound treatment 9.1792867E7 -1.85E7 -1.6 8.5382756E7 -1.5E7 -1.31 -2.0596 -0.9952 2065713 ICCB6_000119 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F10 compound treatment 8.2937007E7 -2.74E7 -2.36 8.6120239E7 -1.43E7 -1.25 -2.5548 -0.9556 2065714 ICCB6_000120 C[C@@H](O)C1=CC[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F11 compound treatment 9.8653616E7 -1.17E7 -1.01 9.2892326E7 -7500000.0 -0.66 -1.1758 -0.9786 1952476 ICCB6_000121 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2c(Br)sc3ccc(Cl)cc23)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F12 compound treatment 8.7315438E7 -2.3E7 -1.99 8.798592E7 -1.24E7 -1.09 -2.1719 -0.9597 2065715 ICCB6_000122 OC[C@@H]1[C@H]2[C@@H](CC=C1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F13 compound treatment 9.2345013E7 -1.8E7 -1.55 9.0930793E7 -9460000.0 -0.83 -1.6825 -0.9568 1952282 ICCB6_000123 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F14 compound treatment 8.5999835E7 -2.43E7 -2.1 8.7055128E7 -1.33E7 -1.17 -2.3099 -0.9616 2065716 ICCB6_000124 CC1=C(CO)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F15 compound treatment 8.144465E7 -2.89E7 -2.49 7.7203238E7 -2.32E7 -2.03 -3.1978 -0.9948 1952488 ICCB6_000125 Fc1ccc(cc1Br)[C@H]2C3=CCC4=C(C3CC5=C2C(=O)C(=CC5=O)I)C(=O)C(=CC4=O)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F16 compound treatment 9.1754388E7 -1.85E7 -1.6 9.0973118E7 -9420000.0 -0.82 -1.716 -0.9523 2065717 ICCB6_000126 C/C(=C/CO)/C(O)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F17 compound treatment 1.03840481E8 -6460000.0 -0.56 9.6857784E7 -3540000.0 -0.31 -0.6136 -0.9613 1952814 ICCB6_000127 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F18 compound treatment 1.00716243E8 -9590000.0 -0.83 9.9117237E7 -1280000.0 -0.11 -0.6646 -0.7954 2065718 ICCB6_000128 CC(C)[Si](OCC1OB(O)CC=C1C)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F19 compound treatment 9.7685875E7 -1.26E7 -1.09 9.5612553E7 -4780000.0 -0.42 -1.0666 -0.9136 1952785 ICCB6_000129 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F20 compound treatment 9.3412146E7 -1.69E7 -1.46 8.8306153E7 -1.21E7 -1.06 -1.7798 -0.9875 2065719 ICCB6_000130 OB1CC=C(C(O1)c2ccccc2)C(=C)COCc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F21 compound treatment 9.5862576E7 -1.44E7 -1.25 7.9049721E7 -2.13E7 -1.87 -2.2029 -0.9807 3107360 ICCB6_000131 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F22 compound treatment 9.2490527E7 -1.78E7 -1.54 8.3897264E7 -1.65E7 -1.44 -2.1089 -0.9995 2065720 ICCB6_000132 OC/C=C(\C(O)c1ccccc1)/C(=C)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F23 mock treatment 1.10390259E8 86100.0 0.01 1.01697927E8 1300000.0 0.11 0.0859 0.7516 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 F24 mock treatment 1.12413678E8 2110000.0 0.18 1.03578659E8 3180000.0 0.28 0.3259 0.9788 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G01 compound treatment 1.07444002E8 -2860000.0 -0.25 9.4345079E7 -6050000.0 -0.53 -0.5491 -0.9398 2065721 ICCB6_000133 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4cccs4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G02 compound treatment 9.689203E7 -1.34E7 -1.16 9.7957123E7 -2440000.0 -0.21 -0.97 -0.8235 3057351 ICCB6_000134 CC(C)C[C@H](CI)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G03 compound treatment 1.11793776E8 1490000.0 0.13 1.02121069E8 1730000.0 0.15 0.1978 0.9968 2065722 ICCB6_000135 Clc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)C(=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G04 compound treatment 9.2849465E7 -1.75E7 -1.51 9.0944037E7 -9450000.0 -0.83 -1.6509 -0.96 3057353 ICCB6_000136 CC(C)(C)OC[C@@H](O)[C@H]1O[C@H](NO)C2OC(C)(C)OC12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G05 compound treatment 9.1641214E7 -1.87E7 -1.61 8.9344567E7 -1.11E7 -0.97 -1.8237 -0.9701 2065723 ICCB6_000137 CCCCCCCNCC(=O)NC[C@H]1O[C@H](O[C@H]2O[C@H](CNC(=O)CCNCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G06 compound treatment 9.9743387E7 -1.06E7 -0.91 9.111498E7 -9280000.0 -0.81 -1.2193 -0.9983 2065724 ICCB6_000138 CC(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G07 compound treatment 9.4007761E7 -1.63E7 -1.41 8.8985816E7 -1.14E7 -1.0 -1.7013 -0.9859 2065725 ICCB6_000139 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G08 compound treatment 8.7585269E7 -2.27E7 -1.96 8.7132652E7 -1.33E7 -1.16 -2.2083 -0.9686 2065726 ICCB6_000140 CC(C)(C)[Si](C)(C)OCC1=CC(C#C)N(C=C1)C(=O)c2ccccc2Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G09 compound treatment 9.0769047E7 -1.95E7 -1.69 8.8349462E7 -1.2E7 -1.05 -1.9385 -0.9744 2065727 ICCB6_000141 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G10 compound treatment 9.3338987E7 -1.7E7 -1.47 8.506975E7 -1.53E7 -1.34 -1.9845 -0.999 3057357 ICCB6_000142 OC(=O)c1[se]c2ccccc2c1Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G11 compound treatment 9.5502943E7 -1.48E7 -1.28 8.8611602E7 -1.18E7 -1.03 -1.6332 -0.9943 1952478 ICCB6_000143 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2ccc3ccccc3c2Br)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G12 compound treatment 7.8620598E7 -3.17E7 -2.74 7.180663E7 -2.86E7 -2.5 -3.7042 -0.999 3057359 ICCB6_000144 CC(C)(C)[Si](C)(C)OCC1=CC(C=C)N(C=C1)C(=O)c2[se]c3ccccc3c2Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G13 compound treatment 9.3861516E7 -1.64E7 -1.42 8.722457E7 -1.32E7 -1.15 -1.8192 -0.9946 1952284 ICCB6_000145 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]2C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G14 compound treatment 9.1102578E7 -1.92E7 -1.66 9.1279135E7 -9120000.0 -0.8 -1.7368 -0.9437 2065728 ICCB6_000146 CCCCCC1C=C(CO[Si](C)(C)C(C)(C)C)C=CN1C(=O)c2ccccc2Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G15 compound treatment 9.7087179E7 -1.32E7 -1.14 9.5539309E7 -4860000.0 -0.42 -1.1077 -0.9094 2065729 ICCB6_000147 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G16 compound treatment 9.661268E7 -1.37E7 -1.18 9.5749854E7 -4640000.0 -0.41 -1.1236 -0.8986 2065730 ICCB6_000148 CC(C)(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G17 compound treatment 1.01539965E8 -8760000.0 -0.76 9.5877359E7 -4520000.0 -0.4 -0.8148 -0.9541 1952760 ICCB6_000149 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G18 compound treatment 8.6216556E7 -2.41E7 -2.08 9.0831485E7 -9560000.0 -0.84 -2.0629 -0.9199 2065731 ICCB6_000150 CC(=O)N[C@@H](CI)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G19 compound treatment 9.5428055E7 -1.49E7 -1.28 9.5369254E7 -5030000.0 -0.44 -1.2195 -0.898 1952788 ICCB6_000151 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G20 compound treatment 8.536642E7 -2.49E7 -2.15 9.2026829E7 -8370000.0 -0.73 -2.0409 -0.8971 2065732 ICCB6_000152 COc1cc2CCN(Cc3ccccc3Br)C(C=C)c2cc1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G21 compound treatment 7.2459829E7 -3.78E7 -3.27 9.6148062E7 -4250000.0 -0.37 -2.5741 -0.7825 1952728 ICCB6_000153 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G22 compound treatment 2.251158E7 -8.78E7 -7.58 9.6571181E7 -3820000.0 -0.33 -5.5985 -0.7376 2065733 ICCB6_000154 CN1C(=O)C2C(C1=O)C3(C4C(C5C=C(CCCO[Si](C)(C)C(C)(C)C)CC2N53)C(=O)N(C)C4=O)C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G23 mock treatment 1.1092609E8 622000.0 0.05 9.6146933E7 -4250000.0 -0.37 -0.2249 -0.5987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 G24 mock treatment 1.07478164E8 -2830000.0 -0.24 1.00938001E8 543000.0 0.05 -0.139 -0.5588 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H01 compound treatment 1.11949327E8 1650000.0 0.14 1.02466151E8 2070000.0 0.18 0.2287 0.9927 2065734 ICCB6_000155 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4Cl)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H02 compound treatment 9.3658355E7 -1.66E7 -1.44 9.1668122E7 -8730000.0 -0.76 -1.5567 -0.9562 2065735 ICCB6_000156 CC(=C)C1=CCB(O)OC1c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H03 compound treatment 1.06477376E8 -3830000.0 -0.33 9.7061627E7 -3330000.0 -0.29 -0.44 -0.9981 2065736 ICCB6_000157 CC(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H04 compound treatment 9.0623587E7 -1.97E7 -1.7 8.8991804E7 -1.14E7 -1.0 -1.9076 -0.9678 2065737 ICCB6_000158 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H05 compound treatment 9.4749759E7 -1.56E7 -1.34 9.122402E7 -9170000.0 -0.8 -1.5175 -0.9697 2065738 ICCB6_000159 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H06 compound treatment 9.2197401E7 -1.81E7 -1.56 8.5742637E7 -1.47E7 -1.28 -2.0126 -0.9951 2065739 ICCB6_000160 CC(=C)/C(=C/CO)/C(O)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H07 compound treatment 9.9828659E7 -1.05E7 -0.9 9.5010129E7 -5380000.0 -0.47 -0.973 -0.9538 2065740 ICCB6_000161 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H08 compound treatment 8.4627382E7 -2.57E7 -2.22 8.084304E7 -1.96E7 -1.71 -2.7781 -0.9918 2065741 ICCB6_000162 CC1=NC(C)(C)[C@@H]2CCC(=C)C1C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H09 compound treatment 9.0946654E7 -1.94E7 -1.67 9.0393744E7 -1.0E7 -0.88 -1.8011 -0.9544 2065742 ICCB6_000163 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H10 compound treatment 9.1380853E7 -1.89E7 -1.63 8.425886E7 -1.61E7 -1.41 -2.1543 -0.9973 2065743 ICCB6_000164 C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H11 compound treatment 9.0795513E7 -1.95E7 -1.69 9.12387E7 -9160000.0 -0.8 -1.7581 -0.9423 1952534 ICCB6_000165 C[C@H](N)C(Oc1ccccc1Br)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H12 compound treatment 8.9211811E7 -2.11E7 -1.82 8.6284467E7 -1.41E7 -1.23 -2.1614 -0.9821 2065744 ICCB6_000166 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H13 compound treatment 1.17702633E8 7400000.0 0.64 1.0773542E8 7340000.0 0.64 0.9061 1.0 1952286 ICCB6_000167 COC(=O)c1nc(oc1CCC=C)C(NC(=O)[C@H](Cc2cn(CC=C)cn2)NC(=O)OCc3ccccc3)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H14 compound treatment 9.3879908E7 -1.64E7 -1.42 8.3543764E7 -1.69E7 -1.47 -2.0459 -0.9998 2065745 ICCB6_000168 CC(C)C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H15 compound treatment 9.5472128E7 -1.48E7 -1.28 9.1139352E7 -9260000.0 -0.81 -1.4786 -0.9756 1952677 ICCB6_000169 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H16 compound treatment 9.3401258E7 -1.69E7 -1.46 8.3902331E7 -1.65E7 -1.44 -2.0529 -1.0 2065746 ICCB6_000170 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H17 compound treatment 9.7836898E7 -1.25E7 -1.08 9.1203739E7 -9190000.0 -0.8 -1.3302 -0.9897 1952821 ICCB6_000171 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H18 compound treatment 9.849442E7 -1.18E7 -1.02 8.8535423E7 -1.19E7 -1.04 -1.4552 -1.0 2065747 ICCB6_000172 COc1cc(C[C@H]2NC(C)(C)C3CCC(=C)[C@H]2C3)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H19 compound treatment 1.03520231E8 -6780000.0 -0.59 9.5671701E7 -4720000.0 -0.41 -0.7066 -0.9854 1952600 ICCB6_000173 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H20 compound treatment 1.00461841E8 -9840000.0 -0.85 9.0953523E7 -9440000.0 -0.83 -1.1854 -0.9999 2065748 ICCB6_000174 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2C)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H21 compound treatment 1.08965165E8 -1340000.0 -0.12 9.9024041E7 -1370000.0 -0.12 -0.1666 -0.9998 1952730 ICCB6_000175 O=c1cc(Cc2ccccc2)c3ccccc3o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H22 compound treatment 1.05170429E8 -5130000.0 -0.44 1.03104942E8 2710000.0 0.24 -0.1458 -0.29 2065749 ICCB6_000176 CC1(C)N=C(/C=C/2\C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H23 mock treatment 1.14808936E8 4500000.0 0.39 9.610593E7 -4290000.0 -0.38 0.0097 0.018 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 H24 mock treatment 1.03296875E8 -7010000.0 -0.61 1.02362213E8 1970000.0 0.17 -0.3062 -0.4866 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I01 compound treatment 1.09282703E8 -1020000.0 -0.09 1.06106736E8 5710000.0 0.5 0.2911 0.5735 2065750 ICCB6_000177 COC(=O)[C@@H]1[C@H](N([C@H](c2ccccc2)[C@@]13C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6)C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I02 compound treatment 9.9970036E7 -1.03E7 -0.89 9.1924486E7 -8470000.0 -0.74 -1.1553 -0.9957 2065751 ICCB6_000178 CC(C)(C)[Si](C)(C)OCCCC1=CC2C3C(C(=O)N(Cc4ccccc4)C3=O)C5(C6C(C(C1)N25)C(=O)N(Cc7ccccc7)C6=O)C(=O)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I03 compound treatment 1.0190725E8 -8400000.0 -0.73 9.8531147E7 -1860000.0 -0.16 -0.6282 -0.845 2065752 ICCB6_000179 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Cl)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I04 compound treatment 9.0542135E7 -1.98E7 -1.71 9.1268388E7 -9130000.0 -0.8 -1.7717 -0.9401 2065753 ICCB6_000180 COc1cc(CN[C@@H](C)[C@H](Oc2ccccc2Br)c3ccccc3)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I05 compound treatment 9.4261768E7 -1.6E7 -1.39 9.3453068E7 -6940000.0 -0.61 -1.4094 -0.9315 2065754 ICCB6_000181 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I06 compound treatment 9.1838151E7 -1.85E7 -1.59 9.058476E7 -9810000.0 -0.86 -1.7349 -0.9578 2065755 ICCB6_000182 COc1cc(CN[C@H]([C@H](O)c2ccccc2)c3ccccc3)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I07 compound treatment 9.2862168E7 -1.74E7 -1.51 9.2218916E7 -8180000.0 -0.72 -1.5712 -0.9421 2065756 ICCB6_000183 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I08 compound treatment 9.4678697E7 -1.56E7 -1.35 8.7087115E7 -1.33E7 -1.16 -1.7778 -0.9973 2065757 ICCB6_000184 COc1cc(CN(Cc2ccccc2Br)[C@H]([C@H](O)c3ccccc3)c4ccccc4)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I09 compound treatment 9.2736705E7 -1.76E7 -1.52 8.9631285E7 -1.08E7 -0.94 -1.739 -0.9737 2065758 ICCB6_000185 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I10 compound treatment 9.4548494E7 -1.58E7 -1.36 9.2807865E7 -7590000.0 -0.66 -1.4318 -0.9456 2065759 ICCB6_000186 COc1cc(CN(Cc2ccccc2Br)[C@H](C)C(Oc3ccccc3Br)c4ccccc4)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I11 compound treatment 9.0488029E7 -1.98E7 -1.71 9.3021703E7 -7370000.0 -0.65 -1.6665 -0.9111 1952544 ICCB6_000187 O=C1Nc2ccccc2[C@@]31[C@@H](C#N)C4N([C@H]3c5ccccc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I12 compound treatment 8.9902296E7 -2.04E7 -1.76 9.0911814E7 -9480000.0 -0.83 -1.8329 -0.941 2065760 ICCB6_000188 COc1cc(CN(Cc2ccccc2Br)[C@H](C(Oc3ccccc3Br)c4ccccc4)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I13 compound treatment 9.0421645E7 -1.99E7 -1.72 9.5464236E7 -4930000.0 -0.43 -1.5194 -0.8581 1952288 ICCB6_000189 COC(=O)c1nc2oc1CC/C=C/Cn3cnc(C[C@H](NC(=O)OCc4ccccc4)C(=O)NC2C(C)C)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I14 compound treatment 8.6896162E7 -2.34E7 -2.02 8.8781036E7 -1.16E7 -1.02 -2.1483 -0.9494 2065761 ICCB6_000190 C[C@@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I15 compound treatment 9.3654067E7 -1.67E7 -1.44 9.2264965E7 -8130000.0 -0.71 -1.52 -0.9473 1952679 ICCB6_000191 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I16 compound treatment 8.9037188E7 -2.13E7 -1.84 8.8360368E7 -1.2E7 -1.05 -2.0436 -0.9651 2065762 ICCB6_000192 C[C@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I17 compound treatment 1.10495369E8 191000.0 0.02 1.07280696E8 6890000.0 0.6 0.4378 0.7262 1952823 ICCB6_000193 C#Cc1ccccc1Oc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I18 compound treatment 9.2406395E7 -1.79E7 -1.55 9.1232626E7 -9160000.0 -0.8 -1.6601 -0.9533 2065763 ICCB6_000194 C[C@H](C(Oc1ccc(cc1)[N+](=O)[O-])c2ccccc2)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I19 compound treatment 6.4798216E7 -4.55E7 -3.93 7.9781656E7 -2.06E7 -1.8 -4.0549 -0.9376 1952601 ICCB6_000195 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I20 compound treatment 8.2410149E7 -2.79E7 -2.41 9.6003787E7 -4390000.0 -0.38 -1.9753 -0.8097 2065764 ICCB6_000196 C[C@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I21 compound treatment 6.1726958E7 -4.86E7 -4.2 8.3469974E7 -1.69E7 -1.48 -4.0142 -0.9022 1952746 ICCB6_000197 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I22 compound treatment 3.9113935E7 -7.12E7 -6.15 9.5953193E7 -4440000.0 -0.39 -4.6228 -0.7503 2065765 ICCB6_000198 C[C@@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I23 mock treatment 1.03198845E8 -7110000.0 -0.61 1.00399392E8 4740.0 0.0 -0.4337 -0.7066 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 I24 mock treatment 1.13333196E8 3030000.0 0.26 1.02284833E8 1890000.0 0.17 0.302 0.9756 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J01 compound treatment 2.5528129E7 -8.48E7 -7.32 2.7803956E7 -7.26E7 -6.35 -9.6699 -0.9975 2065766 ICCB6_000199 COC(=O)C1=CN([C@H](c2ccccc2)[C@]31C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J02 compound treatment 1.00006405E8 -1.03E7 -0.89 9.7623936E7 -2770000.0 -0.24 -0.8004 -0.8682 2065767 ICCB6_000200 CC1(C)N[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J03 compound treatment 1.00153922E8 -1.02E7 -0.88 9.7806206E7 -2590000.0 -0.23 -0.7801 -0.8615 2065768 ICCB6_000201 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Br)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J04 compound treatment 9.3980098E7 -1.63E7 -1.41 9.8021867E7 -2370000.0 -0.21 -1.1438 -0.8026 2065769 ICCB6_000202 CN1[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J05 compound treatment 9.3603801E7 -1.67E7 -1.44 9.3744599E7 -6650000.0 -0.58 -1.4315 -0.9203 2065770 ICCB6_000203 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J06 compound treatment 8.4127506E7 -2.62E7 -2.26 7.8072834E7 -2.23E7 -1.95 -2.9801 -0.9974 2065771 ICCB6_000204 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J07 compound treatment 9.6600638E7 -1.37E7 -1.18 9.3591069E7 -6800000.0 -0.6 -1.258 -0.9495 2065772 ICCB6_000205 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J08 compound treatment 9.3834577E7 -1.65E7 -1.42 8.9994574E7 -1.04E7 -0.91 -1.6495 -0.9767 2065773 ICCB6_000206 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J09 compound treatment 9.2412789E7 -1.79E7 -1.55 9.2949315E7 -7450000.0 -0.65 -1.5535 -0.9263 2065774 ICCB6_000207 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J10 compound treatment 8.5592114E7 -2.47E7 -2.13 8.056115E7 -1.98E7 -1.74 -2.7367 -0.9947 2065775 ICCB6_000208 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J11 compound treatment 9.2297813E7 -1.8E7 -1.56 9.0872022E7 -9520000.0 -0.83 -1.689 -0.9572 2065776 ICCB6_000209 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J12 compound treatment 8.838869E7 -2.19E7 -1.89 9.1545168E7 -8850000.0 -0.77 -1.8861 -0.9222 2065777 ICCB6_000210 OCCOc1cccc(c1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J13 compound treatment 7.5957176E7 -3.43E7 -2.97 7.1466393E7 -2.89E7 -2.53 -3.8879 -0.9969 1952295 ICCB6_000211 COC(=O)c1nc(oc1CC(=O)CCl)C(NC(=O)NC(=O)OC(C)(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J14 compound treatment 8.804571E7 -2.23E7 -1.92 9.1296616E7 -9100000.0 -0.8 -1.9224 -0.9239 2065778 ICCB6_000212 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J15 compound treatment 9.6502856E7 -1.38E7 -1.19 9.5376594E7 -5020000.0 -0.44 -1.1534 -0.908 1952690 ICCB6_000213 COC(=O)CC(C(=O)OC)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J16 compound treatment 8.9165289E7 -2.11E7 -1.83 8.8061144E7 -1.23E7 -1.08 -2.0543 -0.9685 2065779 ICCB6_000214 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC(C(=O)OC)C(=O)OC)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J17 compound treatment 8.7086985E7 -2.32E7 -2.01 8.4081503E7 -1.63E7 -1.43 -2.4275 -0.9861 1952825 ICCB6_000215 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J18 compound treatment 8.605525E7 -2.42E7 -2.09 8.2586508E7 -1.78E7 -1.56 -2.583 -0.9894 2065780 ICCB6_000216 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J19 compound treatment 6.2809483E7 -4.75E7 -4.1 5.2760726E7 -4.76E7 -4.17 -5.8485 -1.0 1952605 ICCB6_000217 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J20 compound treatment 9.7433852E7 -1.29E7 -1.11 9.1354598E7 -9040000.0 -0.79 -1.3455 -0.9861 2065781 ICCB6_000218 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J21 compound treatment 1.05331051E8 -4970000.0 -0.43 1.00386292E8 -8360.0 0.0 -0.3042 -0.7083 3005760 ICCB6_000219 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J22 compound treatment 1.03268385E8 -7040000.0 -0.61 9.3830914E7 -6560000.0 -0.57 -0.8359 -0.9996 2065782 ICCB6_000220 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCNC(=O)N)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J23 mock treatment 1.15286226E8 4980000.0 0.43 1.05883912E8 5490000.0 0.48 0.644 0.9985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 J24 mock treatment 1.07776965E8 -2530000.0 -0.22 1.01479464E8 1080000.0 0.09 -0.0872 -0.3664 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K01 compound treatment 1.04345953E8 -5960000.0 -0.51 9.3457432E7 -6940000.0 -0.61 -0.7932 -0.9966 2065783 ICCB6_000221 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C)c5ccccc52 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K02 compound treatment 9.932289E7 -1.1E7 -0.95 8.3310287E7 -1.71E7 -1.5 -1.7279 -0.9759 2065784 ICCB6_000222 CC(Oc1ccccc1Br)[C@H](N(C)C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K03 compound treatment 8.5354443E7 -2.49E7 -2.15 9.919946E7 -1200000.0 -0.1 -1.5978 -0.7406 2065785 ICCB6_000223 COC(=O)C(C(c1ccc(OC)cc1)[Si](C)(C)c2ccccc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K04 compound treatment 7.0795424E7 -3.95E7 -3.41 9.3676458E7 -6720000.0 -0.59 -2.8287 -0.8169 2065786 ICCB6_000224 C[C@H](C(Oc1ccccc1[N+](=O)[O-])c2ccccc2)N(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K05 compound treatment 7.5986625E7 -3.43E7 -2.96 9.7244137E7 -3150000.0 -0.28 -2.2909 -0.7696 2065787 ICCB6_000225 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K06 compound treatment 7.8567448E7 -3.17E7 -2.74 8.8429086E7 -1.2E7 -1.05 -2.6788 -0.9129 2065788 ICCB6_000226 COc1cc(/C=C/C=O)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K07 compound treatment 9.3374718E7 -1.69E7 -1.46 9.2302573E7 -8090000.0 -0.71 -1.5347 -0.9446 2065789 ICCB6_000227 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)CCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K08 compound treatment 9.0340555E7 -2.0E7 -1.72 8.4907076E7 -1.55E7 -1.36 -2.1777 -0.9929 2065790 ICCB6_000228 COc1cc(/C=C/CN[C@H](C)[C@@H](O)c2ccccc2)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K09 compound treatment 9.3700788E7 -1.66E7 -1.43 8.7499482E7 -1.29E7 -1.13 -1.812 -0.993 2065791 ICCB6_000229 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K10 compound treatment 8.6294999E7 -2.4E7 -2.07 9.1747757E7 -8650000.0 -0.76 -2.0015 -0.9067 2065792 ICCB6_000230 CC(C)[Si](OCC1CCC=CC1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K11 compound treatment 9.1868044E7 -1.84E7 -1.59 8.7699549E7 -1.27E7 -1.11 -1.9116 -0.9845 1034979 ICCB6_000231 c1c(cn2ccccc12)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K12 compound treatment 8.8423661E7 -2.19E7 -1.89 8.8644329E7 -1.18E7 -1.03 -2.0635 -0.9591 2065793 ICCB6_000232 CC1(C)COC(=O)C1OC(=O)C2CC3CCC2C=C3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K13 compound treatment 9.8737201E7 -1.16E7 -1.0 9.5766702E7 -4630000.0 -0.41 -0.9928 -0.921 1952379 ICCB6_000233 CC(C)[Si](OCc1ccc(C=O)o1)(C(C)C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K14 compound treatment 9.4577475E7 -1.57E7 -1.36 8.9851686E7 -1.05E7 -0.92 -1.6129 -0.9822 2065794 ICCB6_000234 OCC1CC2CCC1C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K15 compound treatment 1.05558363E8 -4750000.0 -0.41 1.05632285E8 5240000.0 0.46 0.0343 0.0558 1952707 ICCB6_000235 CCCCSc1cc(=O)oc2cc(OC)ccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K16 compound treatment 2.0518997E7 -8.98E7 -7.75 2.0366807E7 -8.0E7 -7.0 -10.436 -0.9987 2065795 ICCB6_000236 Ic1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K17 compound treatment 2.3137844E7 -8.72E7 -7.53 2.5022461E7 -7.54E7 -6.6 -9.988 -0.9978 1952828 ICCB6_000237 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K18 compound treatment 9.3904444E7 -1.64E7 -1.42 9.4630734E7 -5760000.0 -0.5 -1.3583 -0.9034 2065796 ICCB6_000238 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3cccnc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K19 compound treatment 8.559474E7 -2.47E7 -2.13 9.8178393E7 -2220000.0 -0.19 -1.6463 -0.7682 1952608 ICCB6_000239 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K20 compound treatment 7.5915579E7 -3.44E7 -2.97 8.3811829E7 -1.66E7 -1.45 -3.1265 -0.9457 2065797 ICCB6_000240 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3ccco3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K21 compound treatment 7.8801087E7 -3.15E7 -2.72 9.8723938E7 -1670000.0 -0.15 -2.0274 -0.744 3005761 ICCB6_000241 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K22 compound treatment 3.4653782E7 -7.57E7 -6.53 2.9839799E7 -7.06E7 -6.17 -8.9865 -0.9996 2065798 ICCB6_000242 Ic1ccc2NC(=O)/C(=C/C#N)/c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K23 mock treatment 1.1267665E8 2370000.0 0.2 9.8222606E7 -2170000.0 -0.19 0.0105 0.0375 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 K24 mock treatment 1.13298155E8 2990000.0 0.26 9.8919722E7 -1470000.0 -0.13 0.0916 0.3169 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L01 compound treatment 9.2298324E7 -1.8E7 -1.56 8.7861597E7 -1.25E7 -1.1 -1.8753 -0.9854 2065799 ICCB6_000243 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccccc52 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L02 compound treatment 9.1282471E7 -1.9E7 -1.64 9.7577192E7 -2820000.0 -0.25 -1.3361 -0.8042 2065800 ICCB6_000244 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#Cc6ccccc6F)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L03 compound treatment 7.6152143E7 -3.42E7 -2.95 8.8087127E7 -1.23E7 -1.08 -2.8475 -0.9067 2065801 ICCB6_000245 COC(=O)C(C(c1ccco1)[Si](C)(C)c2ccccc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L04 compound treatment 7.0957667E7 -3.93E7 -3.4 8.9697978E7 -1.07E7 -0.94 -3.065 -0.8695 2065802 ICCB6_000246 CCCCC[C@H](O)C#Cc1ccc2NC(=O)[C@@]3([C@H](C4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N(C)OC)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L05 compound treatment 7.4279922E7 -3.6E7 -3.11 9.0519429E7 -9880000.0 -0.86 -2.8113 -0.8706 2065803 ICCB6_000247 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L06 compound treatment 7.4691317E7 -3.56E7 -3.08 8.481263E7 -1.56E7 -1.36 -3.1393 -0.933 2065804 ICCB6_000248 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)[C@H](C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L07 compound treatment 9.4285578E7 -1.6E7 -1.38 9.6501193E7 -3890000.0 -0.34 -1.2193 -0.8557 2065805 ICCB6_000249 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L08 compound treatment 7.6326973E7 -3.4E7 -2.93 7.7304864E7 -2.31E7 -2.02 -3.504 -0.9834 2065806 ICCB6_000250 OCCOc1ccc(cc1)C2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L09 compound treatment 9.3989629E7 -1.63E7 -1.41 8.8140127E7 -1.23E7 -1.07 -1.7548 -0.9909 2065807 ICCB6_000251 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L10 compound treatment 8.6418874E7 -2.39E7 -2.06 9.3442475E7 -6950000.0 -0.61 -1.889 -0.8783 2065808 ICCB6_000252 CON(C)C(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(I)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L11 compound treatment 9.3224177E7 -1.71E7 -1.48 9.0342363E7 -1.01E7 -0.88 -1.6652 -0.9695 2065809 ICCB6_000253 COC(=O)Cc1cn[nH]c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L12 compound treatment 8.020338E7 -3.01E7 -2.6 8.7099224E7 -1.33E7 -1.16 -2.6612 -0.9343 2065810 ICCB6_000254 CCOC(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(Br)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L13 compound treatment 8.8109465E7 -2.22E7 -1.92 8.3573289E7 -1.68E7 -1.47 -2.3965 -0.9915 1952411 ICCB6_000255 CC(C)[Si](OCc1ccc(o1)[C@@H](O)[C@H](C)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3)(C(C)C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L14 compound treatment 8.5331574E7 -2.5E7 -2.16 8.0418497E7 -2.0E7 -1.75 -2.7614 -0.9946 2065811 ICCB6_000256 OCCOc1ccc(cc1)C2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L15 compound treatment 8.9386767E7 -2.09E7 -1.81 8.7330668E7 -1.31E7 -1.14 -2.086 -0.9756 1952793 ICCB6_000257 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L16 compound treatment 8.6177622E7 -2.41E7 -2.08 8.8721401E7 -1.17E7 -1.02 -2.1959 -0.9462 2065812 ICCB6_000258 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L17 compound treatment 9.9070668E7 -1.12E7 -0.97 9.2519176E7 -7880000.0 -0.69 -1.1734 -0.986 1952829 ICCB6_000259 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L18 compound treatment 7.3903334E7 -3.64E7 -3.14 7.725043E7 -2.31E7 -2.03 -3.6554 -0.9774 2065813 ICCB6_000260 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L19 compound treatment 1.02838979E8 -7470000.0 -0.64 9.9776706E7 -618000.0 -0.05 -0.4942 -0.7637 1952582 ICCB6_000261 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L20 compound treatment 8.7564175E7 -2.27E7 -1.96 8.7760069E7 -1.26E7 -1.11 -2.1707 -0.9631 2065814 ICCB6_000262 CON(C)C(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(Br)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L21 compound treatment 1.076629E8 -2640000.0 -0.23 1.01536272E8 1140000.0 0.1 -0.0907 -0.364 1952748 ICCB6_000263 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L22 compound treatment 9.3581104E7 -1.67E7 -1.44 8.6184936E7 -1.42E7 -1.24 -1.9007 -0.9972 2065815 ICCB6_000264 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L23 mock treatment 1.11744795E8 1440000.0 0.12 1.04652339E8 4260000.0 0.37 0.3515 0.8947 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 L24 mock treatment 1.11020497E8 716000.0 0.06 1.00688194E8 294000.0 0.03 0.0619 0.9242 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M01 compound treatment 5.3161221E7 -5.71E7 -4.94 5.2574203E7 -4.78E7 -4.19 -6.4493 -0.9966 2065816 ICCB6_000265 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccc(Cl)cc52 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M02 compound treatment 9.8319629E7 -1.2E7 -1.04 8.4891268E7 -1.55E7 -1.36 -1.6914 -0.9911 2065817 ICCB6_000266 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M03 compound treatment 1.16627214E8 6320000.0 0.55 1.08327346E8 7930000.0 0.69 0.8771 0.9929 2065818 ICCB6_000267 COc1ccc(cc1)C(CC(=O)c2ccccc2)[Si](C)(C)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M04 compound treatment 9.7871272E7 -1.24E7 -1.07 9.3350473E7 -7040000.0 -0.62 -1.1953 -0.9653 2065819 ICCB6_000268 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M05 compound treatment 9.3579419E7 -1.67E7 -1.44 9.1282651E7 -9110000.0 -0.8 -1.5853 -0.9608 2065820 ICCB6_000269 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M06 compound treatment 2.287199E7 -8.74E7 -7.55 2.5541944E7 -7.49E7 -6.55 -9.9721 -0.9975 2065821 ICCB6_000270 COC(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M07 compound treatment 7.2479679E7 -3.78E7 -3.27 9.3656484E7 -6740000.0 -0.59 -2.7271 -0.8215 2065822 ICCB6_000271 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M08 compound treatment 7.5454245E7 -3.48E7 -3.01 8.5613377E7 -1.48E7 -1.29 -3.0432 -0.9289 2065823 ICCB6_000272 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCC4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M09 compound treatment 9.7614056E7 -1.27E7 -1.1 9.562197E7 -4770000.0 -0.42 -1.0704 -0.9126 2065824 ICCB6_000273 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M10 compound treatment 9.3219566E7 -1.71E7 -1.48 8.9449977E7 -1.09E7 -0.96 -1.7207 -0.9781 2065825 ICCB6_000274 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4ccccc4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M11 compound treatment 8.0490175E7 -2.98E7 -2.58 8.6729181E7 -1.37E7 -1.2 -2.6665 -0.9392 2065826 ICCB6_000275 CC(C(=O)O)c1ccccc1C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M12 compound treatment 9.6513686E7 -1.38E7 -1.19 1.0181086E8 1420000.0 0.12 -0.7546 -0.6301 2065827 ICCB6_000276 OCCNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(I)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M13 compound treatment 9.0306302E7 -2.0E7 -1.73 9.3704207E7 -6690000.0 -0.59 -1.6354 -0.8967 1952416 ICCB6_000277 Clc1c(Cl)c(Cl)c(OCc2ccccc2)c(Cl)c1Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M14 compound treatment 8.778311E7 -2.25E7 -1.95 8.4580591E7 -1.58E7 -1.38 -2.3541 -0.9861 2065828 ICCB6_000278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M15 compound treatment 8.4192997E7 -2.61E7 -2.26 8.9223965E7 -1.12E7 -0.98 -2.286 -0.93 1952795 ICCB6_000279 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M16 compound treatment 7.0321903E7 -4.0E7 -3.45 9.1220704E7 -9170000.0 -0.8 -3.0096 -0.8489 2065829 ICCB6_000280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)C(C(OC3=O)c5ccccc5)c6ccccc6)C(=O)N(C)OC)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M17 compound treatment 9.0530327E7 -1.98E7 -1.71 9.560812E7 -4790000.0 -0.42 -1.5039 -0.8552 1952832 ICCB6_000281 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M18 compound treatment 9.1559544E7 -1.87E7 -1.62 9.0987981E7 -9410000.0 -0.82 -1.7269 -0.9508 3176523 ICCB6_000282 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCC(C)C)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M19 compound treatment 9.1821919E7 -1.85E7 -1.6 9.9124141E7 -1270000.0 -0.11 -1.2074 -0.7545 1952627 ICCB6_000283 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M20 compound treatment 9.028776E7 -2.0E7 -1.73 9.0288007E7 -1.01E7 -0.88 -1.8479 -0.9516 3056713 ICCB6_000284 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@@H](C(C)C)C(=O)OC)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M21 compound treatment 4.5526742E7 -6.48E7 -5.59 8.6775788E7 -1.36E7 -1.19 -4.799 -0.8389 1107217 ICCB6_000285 Cc1cccnc1I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M22 compound treatment 4.8463705E7 -6.18E7 -5.34 9.3371994E7 -7020000.0 -0.61 -4.2115 -0.7833 3176524 ICCB6_000286 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@H](C)c5ccccc5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M23 mock treatment 1.11664713E8 1360000.0 0.12 1.04583228E8 4190000.0 0.37 0.3423 0.8892 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 M24 mock treatment 1.08504263E8 -1800000.0 -0.16 1.03496512E8 3100000.0 0.27 0.082 0.2622 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N01 compound treatment 1.03215054E8 -7090000.0 -0.61 1.00279172E8 -115000.0 -0.01 -0.4401 -0.7187 2065830 ICCB6_000287 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccc(Cl)cc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N02 compound treatment 9.1613368E7 -1.87E7 -1.61 9.2614334E7 -7780000.0 -0.68 -1.623 -0.9263 2065831 ICCB6_000288 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N03 compound treatment 1.10820584E8 516000.0 0.04 1.08078356E8 7680000.0 0.67 0.507 0.7524 2065832 ICCB6_000289 C[Si](C)(F)C(CC(=O)c1ccccc1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N04 compound treatment 8.6900609E7 -2.34E7 -2.02 8.2687221E7 -1.77E7 -1.55 -2.5252 -0.9914 2065833 ICCB6_000290 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N(C)OC)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N05 compound treatment 9.8776402E7 -1.15E7 -1.0 9.782337E7 -2570000.0 -0.23 -0.8632 -0.8456 2065834 ICCB6_000291 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N06 compound treatment 9.1415836E7 -1.89E7 -1.63 9.3675127E7 -6720000.0 -0.59 -1.5694 -0.905 2065835 ICCB6_000292 CC1(C)N[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC1CCC4=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N07 compound treatment 7.0688919E7 -3.96E7 -3.42 9.4117817E7 -6280000.0 -0.55 -2.8079 -0.8103 2065836 ICCB6_000293 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N08 compound treatment 7.5022288E7 -3.53E7 -3.05 9.5559416E7 -4840000.0 -0.42 -2.454 -0.7976 2065837 ICCB6_000294 CN1[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N09 compound treatment 9.4395528E7 -1.59E7 -1.37 9.7219059E7 -3180000.0 -0.28 -1.1681 -0.8333 2065838 ICCB6_000295 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N10 compound treatment 8.7914026E7 -2.24E7 -1.93 8.6465456E7 -1.39E7 -1.22 -2.2295 -0.9752 2065839 ICCB6_000296 Cc1ccc(cc1)S(=O)(=O)N[C@H]2CC3CCC2(C)C3(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N11 compound treatment 9.530616E7 -1.5E7 -1.3 9.6476639E7 -3920000.0 -0.34 -1.1585 -0.8645 2065840 ICCB6_000297 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N12 compound treatment 8.9816107E7 -2.05E7 -1.77 1.00863796E8 469000.0 0.04 -1.2223 -0.6905 2065841 ICCB6_000298 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N13 compound treatment 9.3075178E7 -1.72E7 -1.49 9.1887783E7 -8510000.0 -0.74 -1.5787 -0.9488 1952445 ICCB6_000299 Clc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc(CNC(=O)OCc5ccccc5)cc4)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N14 compound treatment 9.6852936E7 -1.35E7 -1.16 9.6349188E7 -4050000.0 -0.35 -1.0719 -0.8825 2065842 ICCB6_000300 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N15 compound treatment 7.4874491E7 -3.54E7 -3.06 8.9668495E7 -1.07E7 -0.94 -2.8276 -0.8834 1952801 ICCB6_000301 Oc1ccccc1C#Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N16 compound treatment 7.1632653E7 -3.87E7 -3.34 9.1274588E7 -9120000.0 -0.8 -2.9262 -0.8521 2065843 ICCB6_000302 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N17 compound treatment 5.1086322E7 -5.92E7 -5.11 4.6347272E7 -5.4E7 -4.73 -6.9614 -0.9992 1952836 ICCB6_000303 CC(=O)c1ccc2oc(cc2c1)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N18 compound treatment 9.5388291E7 -1.49E7 -1.29 8.8862283E7 -1.15E7 -1.01 -1.6246 -0.9927 2065844 ICCB6_000304 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N19 compound treatment 1.0093514E8 -9370000.0 -0.81 9.8242802E7 -2150000.0 -0.19 -0.7054 -0.849 1952631 ICCB6_000305 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N20 compound treatment 1.00158279E8 -1.01E7 -0.88 9.9918709E7 -476000.0 -0.04 -0.6491 -0.7399 2065845 ICCB6_000306 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N21 compound treatment 9.6296752E7 -1.4E7 -1.21 9.2593083E7 -7800000.0 -0.68 -1.3383 -0.9633 3005761 ICCB6_000307 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N22 compound treatment 1.07709344E8 -2590000.0 -0.22 1.00976234E8 582000.0 0.05 -0.1225 -0.5329 2065846 ICCB6_000308 CN(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)Cc8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N23 mock treatment 1.13100333E8 2800000.0 0.24 1.04319695E8 3930000.0 0.34 0.4137 0.9851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 N24 mock treatment 1.01935596E8 -8370000.0 -0.72 9.5936738E7 -4460000.0 -0.39 -0.787 -0.9581 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O01 compound treatment 1.11042077E8 738000.0 0.06 1.02293379E8 1900000.0 0.17 0.1626 0.9134 2065847 ICCB6_000309 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3cccc(F)c3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O02 compound treatment 1.02664999E8 -7640000.0 -0.66 9.7354868E7 -3040000.0 -0.27 -0.6547 -0.9202 3176588 ICCB6_000310 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)NCc5ccc(Cl)c(Cl)c5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O03 compound treatment 1.03582507E8 -6720000.0 -0.58 1.03103262E8 2710000.0 0.24 -0.2429 -0.3873 2065848 ICCB6_000311 Cc1ccc(cc1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O04 compound treatment 1.02805863E8 -7500000.0 -0.65 9.9363938E7 -1030000.0 -0.09 -0.5217 -0.7979 3176589 ICCB6_000312 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCc5ccc(cc5)[N+](=O)[O-])c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O05 compound treatment 1.02321052E8 -7980000.0 -0.69 1.02942343E8 2550000.0 0.22 -0.3299 -0.4552 2065849 ICCB6_000313 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)CCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O06 compound treatment 1.03683017E8 -6620000.0 -0.57 9.5921681E7 -4470000.0 -0.39 -0.6812 -0.9829 2065850 ICCB6_000314 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(Br)cc4)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O07 compound treatment 9.9781959E7 -1.05E7 -0.91 9.3473307E7 -6920000.0 -0.61 -1.071 -0.9806 2065851 ICCB6_000315 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O08 compound treatment 9.9606675E7 -1.07E7 -0.92 9.5042286E7 -5350000.0 -0.47 -0.9846 -0.9504 2065852 ICCB6_000316 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(cc4)[N+](=O)[O-])cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O09 compound treatment 9.8357838E7 -1.19E7 -1.03 8.0278576E7 -2.01E7 -1.76 -1.9745 -0.9676 2065853 ICCB6_000317 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O10 compound treatment 9.9179747E7 -1.11E7 -0.96 9.3416867E7 -6980000.0 -0.61 -1.1112 -0.9761 2065854 ICCB6_000318 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O11 compound treatment 9.6714901E7 -1.36E7 -1.17 9.4413751E7 -5980000.0 -0.52 -1.2001 -0.9338 2065855 ICCB6_000319 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O12 compound treatment 9.70501E7 -1.33E7 -1.14 9.2643271E7 -7750000.0 -0.68 -1.2892 -0.9688 2065856 ICCB6_000320 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O13 compound treatment 8.1205263E7 -2.91E7 -2.51 9.7190822E7 -3200000.0 -0.28 -1.9755 -0.7811 1952450 ICCB6_000321 CCOC(=O)C(O)C(O)c1ccc(CO[Si](C(C)C)(C(C)C)c2ccccc2)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O14 compound treatment 7.8087494E7 -3.22E7 -2.78 9.4632273E7 -5760000.0 -0.5 -2.3242 -0.8219 2065857 ICCB6_000322 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O15 compound treatment 9.5913552E7 -1.44E7 -1.24 9.4152381E7 -6240000.0 -0.55 -1.2652 -0.9319 1952761 ICCB6_000323 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O16 compound treatment 1.06494832E8 -3810000.0 -0.33 9.6244691E7 -4150000.0 -0.36 -0.4895 -0.9988 2065858 ICCB6_000324 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O17 compound treatment 1.03636702E8 -6670000.0 -0.58 9.7912443E7 -2480000.0 -0.22 -0.5608 -0.9112 1952837 ICCB6_000325 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O18 compound treatment 9.1335956E7 -1.9E7 -1.64 8.8836136E7 -1.16E7 -1.01 -1.8738 -0.9732 2065859 ICCB6_000326 CO[C@H]1O[C@@H]2COC(O[C@H]2[C@H](OC(=O)/C=C/C=C/C)[C@H]1OC(=O)/C=C/C=C/C)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O19 compound treatment 8.8386265E7 -2.19E7 -1.89 9.5673326E7 -4720000.0 -0.41 -1.6308 -0.8416 1952633 ICCB6_000327 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O20 compound treatment 8.8471584E7 -2.18E7 -1.89 9.8711329E7 -1680000.0 -0.15 -1.4376 -0.76 2065860 ICCB6_000328 CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COC(c2ccccc2)(c3ccccc3)c4ccccc4)O[C@H](CC=C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1N=[N+]=[N-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O21 compound treatment 8.0422547E7 -2.99E7 -2.58 1.03069651E8 2670000.0 0.23 -1.6595 -0.6403 1952755 ICCB6_000329 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O22 compound treatment 4.0698762E7 -6.96E7 -6.01 1.02040779E8 1650000.0 0.14 -4.1492 -0.69 2065861 ICCB6_000330 C[C@H]1[C@H](OC(=O)N1C(=O)[C@@H](CC=C)C(C)(C)C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O23 mock treatment 1.10864683E8 561000.0 0.05 1.00675888E8 281000.0 0.02 0.0516 0.9508 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 O24 mock treatment 1.14646145E8 4340000.0 0.38 9.8508579E7 -1890000.0 -0.17 0.1485 0.3623 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P01 compound treatment 1.06784229E8 -3520000.0 -0.3 1.01658782E8 1260000.0 0.11 -0.1367 -0.4227 2065862 ICCB6_000331 CC1(C)OCC2=C(CC(CCc3ccccc3)OC2CCc4ccccc4)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P02 compound treatment 9.2396055E7 -1.79E7 -1.55 9.5146294E7 -5250000.0 -0.46 -1.4185 -0.8791 2065863 ICCB6_000332 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P03 compound treatment 1.12702846E8 2400000.0 0.21 9.6728529E7 -3670000.0 -0.32 -0.0804 -0.2104 2065864 ICCB6_000333 C1CCC(CC1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P04 compound treatment 1.01764922E8 -8540000.0 -0.74 9.8340327E7 -2050000.0 -0.18 -0.6487 -0.8545 2065865 ICCB6_000334 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P05 compound treatment 1.03370912E8 -6930000.0 -0.6 1.02072366E8 1680000.0 0.15 -0.3196 -0.5184 2065866 ICCB6_000335 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P06 compound treatment 1.02314314E8 -7990000.0 -0.69 9.6517964E7 -3880000.0 -0.34 -0.7279 -0.9465 2065867 ICCB6_000336 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P07 compound treatment 9.9917511E7 -1.04E7 -0.9 9.1559656E7 -8830000.0 -0.77 -1.1811 -0.9973 2065868 ICCB6_000337 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P08 compound treatment 1.04546428E8 -5760000.0 -0.5 9.5172961E7 -5220000.0 -0.46 -0.6748 -0.9991 2065869 ICCB6_000338 C[C@H](Cc1ccccc1)N(C)CC#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P09 compound treatment 1.03700715E8 -6600000.0 -0.57 1.00052972E8 -342000.0 -0.03 -0.4244 -0.7432 2065870 ICCB6_000339 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P10 compound treatment 9.7298306E7 -1.3E7 -1.12 9.3653129E7 -6740000.0 -0.59 -1.2115 -0.9548 2065871 ICCB6_000340 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P11 compound treatment 2.0554147E7 -8.97E7 -7.75 2.0468627E7 -7.99E7 -6.99 -10.4276 -0.9987 2065872 ICCB6_000341 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P12 compound treatment 1.00166054E8 -1.01E7 -0.88 9.6920537E7 -3470000.0 -0.3 -0.8342 -0.8999 2065873 ICCB6_000342 CCOC(OCC)C#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P13 compound treatment 7.4980338E7 -3.53E7 -3.05 7.8451772E7 -2.19E7 -1.92 -3.5153 -0.9751 2065874 ICCB6_000343 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P14 compound treatment 2.0657034E7 -8.96E7 -7.74 2.0811299E7 -7.96E7 -6.96 -10.4001 -0.9986 2065875 ICCB6_000344 Brc1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P15 compound treatment 1.13648468E8 3340000.0 0.29 1.07721697E8 7330000.0 0.64 0.6577 0.9351 1952804 ICCB6_000345 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P16 compound treatment 2.3985473E7 -8.63E7 -7.46 2.2928507E7 -7.75E7 -6.78 -10.0658 -0.9989 2065876 ICCB6_000346 CCOC(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P17 compound treatment 1.05181753E8 -5120000.0 -0.44 9.915378E7 -1240000.0 -0.11 -0.3896 -0.8553 1952838 ICCB6_000347 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P18 compound treatment 2.5892352E7 -8.44E7 -7.29 3.0383709E7 -7.0E7 -6.13 -9.488 -0.9963 2065877 ICCB6_000348 O=C(/C=C\1/C(=O)Nc2ccccc12)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P19 compound treatment 9.3632564E7 -1.67E7 -1.44 8.9016816E7 -1.14E7 -1.0 -1.7223 -0.9838 1952634 ICCB6_000349 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P20 compound treatment 4.7385425E7 -6.29E7 -5.43 3.1678527E7 -6.87E7 -6.01 -8.0952 -0.9987 2065878 ICCB6_000350 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P21 compound treatment 1.12208029E8 1900000.0 0.16 9.6882767E7 -3510000.0 -0.31 -0.101 -0.2899 1952770 ICCB6_000351 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P22 compound treatment 3.091894E7 -7.94E7 -6.86 2.7839941E7 -7.26E7 -6.35 -9.3384 -0.9993 2065879 ICCB6_000352 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P23 mock treatment 1.15051149E8 4750000.0 0.41 1.04009756E8 3620000.0 0.32 0.5136 0.9918 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.1463 P24 mock treatment 1.17467212E8 7160000.0 0.62 1.01451529E8 1060000.0 0.09 0.5029 0.8039 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A01 mock treatment 1.05242254E8 2660000.0 0.23 1.06114791E8 3860000.0 0.34 0.4012 0.9822 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A02 mock treatment 9.7890826E7 -4690000.0 -0.41 1.05622487E8 3370000.0 0.29 -0.0783 -0.1562 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A03 compound treatment 1.00568462E8 -2020000.0 -0.17 9.7506144E7 -4750000.0 -0.42 -0.417 -0.9255 3000673 BCB01_000001 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A04 compound treatment 1.05828274E8 3240000.0 0.28 9.4167006E7 -8090000.0 -0.71 -0.3024 -0.3973 3000674 BCB01_000002 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A05 compound treatment 9.8963288E7 -3620000.0 -0.31 9.4612443E7 -7640000.0 -0.67 -0.6941 -0.9401 3000675 BCB01_000003 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A06 compound treatment 8.7378769E7 -1.52E7 -1.31 1.00315173E8 -1940000.0 -0.17 -1.0487 -0.7919 3000676 BCB01_000004 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A07 compound treatment 9.8085224E7 -4500000.0 -0.39 9.7304084E7 -4950000.0 -0.43 -0.5812 -0.9985 3093034 BCB01_000005 COc1cc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A08 compound treatment 9.5812443E7 -6770000.0 -0.59 8.7066775E7 -1.52E7 -1.33 -1.3535 -0.932 3000677 BCB01_000006 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A09 compound treatment 9.1455538E7 -1.11E7 -0.96 9.4008741E7 -8250000.0 -0.72 -1.19 -0.99 3093035 BCB01_000007 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A10 compound treatment 8.4361719E7 -1.82E7 -1.57 9.4929708E7 -7320000.0 -0.64 -1.5663 -0.9216 3000678 BCB01_000008 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A11 compound treatment 9.3346826E7 -9240000.0 -0.8 8.5129954E7 -1.71E7 -1.5 -1.624 -0.9565 3093104 BCB01_000009 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A12 compound treatment 8.5420563E7 -1.72E7 -1.48 8.4864402E7 -1.74E7 -1.52 -2.1245 -0.9999 3093105 BCB01_000010 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A13 compound treatment 8.5347336E7 -1.72E7 -1.49 9.2182888E7 -1.01E7 -0.88 -1.6761 -0.9687 3000679 BCB01_000011 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A14 compound treatment 9.316876E7 -9420000.0 -0.81 8.7188905E7 -1.51E7 -1.32 -1.5074 -0.9731 3093106 BCB01_000012 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A15 compound treatment 7.0725621E7 -3.19E7 -2.75 6.232597E7 -3.99E7 -3.49 -4.4168 -0.993 3093107 BCB01_000013 CCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A16 compound treatment 8.9570331E7 -1.3E7 -1.12 9.252422E7 -9730000.0 -0.85 -1.397 -0.9906 3000680 BCB01_000014 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A17 compound treatment 8.7758852E7 -1.48E7 -1.28 9.7017886E7 -5240000.0 -0.46 -1.2296 -0.904 3093108 BCB01_000015 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A18 compound treatment 9.7940041E7 -4650000.0 -0.4 9.0583449E7 -1.17E7 -1.02 -1.006 -0.9167 3093109 BCB01_000016 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A19 compound treatment 9.9505042E7 -3080000.0 -0.27 1.00493016E8 -1760000.0 -0.15 -0.2971 -0.9663 3000681 BCB01_000017 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A20 compound treatment 9.71828E7 -5400000.0 -0.47 1.02196333E8 -57800.0 -0.01 -0.3336 -0.7147 3093110 BCB01_000018 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A21 compound treatment 9.1683483E7 -1.09E7 -0.94 1.02810507E8 556000.0 0.05 -0.6314 -0.6696 3000682 BCB01_000019 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A22 compound treatment 1.00726387E8 -1860000.0 -0.16 9.2830502E7 -9420000.0 -0.82 -0.6967 -0.8292 3093111 BCB01_000020 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A23 mock treatment 1.05588056E8 3000000.0 0.26 1.05459651E8 3210000.0 0.28 0.3817 0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 A24 mock treatment 1.01153654E8 -1430000.0 -0.12 1.05672501E8 3420000.0 0.3 0.1241 0.3833 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B01 mock treatment 1.04404972E8 1820000.0 0.16 1.00177458E8 -2080000.0 -0.18 -0.0174 -0.0724 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B02 mock treatment 9.898012E7 -3610000.0 -0.31 1.0111967E8 -1130000.0 -0.1 -0.2904 -0.8885 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B03 compound treatment 9.8508742E7 -4080000.0 -0.35 8.7424044E7 -1.48E7 -1.3 -1.1667 -0.8676 3093112 BCB01_000021 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B04 compound treatment 8.6061144E7 -1.65E7 -1.43 9.5282661E7 -6970000.0 -0.61 -1.4406 -0.9281 3000683 BCB01_000022 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B05 compound treatment 9.3490827E7 -9090000.0 -0.79 9.5258317E7 -7000000.0 -0.61 -0.9884 -0.9924 3093113 BCB01_000023 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B06 compound treatment 9.7393145E7 -5190000.0 -0.45 9.640387E7 -5850000.0 -0.51 -0.6792 -0.9978 3093114 BCB01_000024 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B07 compound treatment 7.6317203E7 -2.63E7 -2.27 7.7725968E7 -2.45E7 -2.15 -3.1222 -0.9996 3000684 BCB01_000025 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B08 compound treatment 8.7328073E7 -1.53E7 -1.32 9.5488907E7 -6770000.0 -0.59 -1.3505 -0.9348 3093115 BCB01_000026 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B09 compound treatment 8.8595875E7 -1.4E7 -1.21 9.4235514E7 -8020000.0 -0.7 -1.3506 -0.9666 3093116 BCB01_000027 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B10 compound treatment 9.1260677E7 -1.13E7 -0.98 9.1195745E7 -1.11E7 -0.97 -1.376 -1.0 3000685 BCB01_000028 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B11 compound treatment 9.2436758E7 -1.01E7 -0.88 8.3130676E7 -1.91E7 -1.67 -1.8033 -0.9545 3093117 BCB01_000029 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(C)cc(C)cc4C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B12 compound treatment 7.1989421E7 -3.06E7 -2.64 8.5022833E7 -1.72E7 -1.51 -2.935 -0.9646 3093118 BCB01_000030 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B13 compound treatment 9.0331975E7 -1.23E7 -1.06 9.315951E7 -9090000.0 -0.8 -1.3112 -0.9901 3000686 BCB01_000031 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B14 compound treatment 9.1246371E7 -1.13E7 -0.98 9.0586735E7 -1.17E7 -1.02 -1.4146 -0.9998 3093119 BCB01_000032 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B15 compound treatment 9.5731311E7 -6850000.0 -0.59 8.7181363E7 -1.51E7 -1.32 -1.3514 -0.9346 3093120 BCB01_000033 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(c4ccccc4)c5ccccc5)C(=O)N(C3=O)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B16 compound treatment 8.2426867E7 -2.02E7 -1.74 8.5567564E7 -1.67E7 -1.46 -2.2638 -0.9962 3000687 BCB01_000034 CCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B17 compound treatment 9.3464585E7 -9120000.0 -0.79 9.8571833E7 -3680000.0 -0.32 -0.7849 -0.9222 3000688 BCB01_000035 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B18 compound treatment 8.7911473E7 -1.47E7 -1.27 8.8313321E7 -1.39E7 -1.22 -1.7589 -0.9998 3093121 BCB01_000036 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B19 compound treatment 1.01390734E8 -1190000.0 -0.1 9.3161317E7 -9090000.0 -0.8 -0.6357 -0.7922 3093122 BCB01_000037 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B20 compound treatment 8.8195231E7 -1.44E7 -1.24 9.5763857E7 -6490000.0 -0.57 -1.2805 -0.937 3093123 BCB01_000038 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B21 compound treatment 9.7112254E7 -5470000.0 -0.47 1.02314328E8 60200.0 0.01 -0.3306 -0.6992 3000689 BCB01_000039 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B22 compound treatment 9.5225177E7 -7360000.0 -0.64 1.02685584E8 431000.0 0.04 -0.4228 -0.6639 3093124 BCB01_000040 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B23 mock treatment 1.05306647E8 2720000.0 0.24 9.7179861E7 -5070000.0 -0.44 -0.1478 -0.2942 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 B24 mock treatment 9.4708609E7 -7880000.0 -0.68 1.0431393E8 2060000.0 0.18 -0.3536 -0.5024 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C01 mock treatment 1.05688128E8 3100000.0 0.27 9.680122E7 -5450000.0 -0.48 -0.148 -0.2703 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C02 mock treatment 1.01562172E8 -1020000.0 -0.09 9.9263722E7 -2990000.0 -0.26 -0.2476 -0.8962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C03 compound treatment 1.00871573E8 -1710000.0 -0.15 9.6447431E7 -5810000.0 -0.51 -0.464 -0.8767 3000690 BCB01_000041 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C04 compound treatment 9.1867179E7 -1.07E7 -0.93 1.00022901E8 -2230000.0 -0.2 -0.7927 -0.8378 3093125 BCB01_000042 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C05 compound treatment 9.5385016E7 -7200000.0 -0.62 8.6305909E7 -1.59E7 -1.4 -1.4267 -0.9337 3093282 BCB01_000043 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C06 compound treatment 9.8121326E7 -4460000.0 -0.39 9.2896501E7 -9360000.0 -0.82 -0.8517 -0.941 3000691 BCB01_000044 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C07 compound treatment 9.5458915E7 -7130000.0 -0.62 9.4720154E7 -7530000.0 -0.66 -0.9015 -0.9994 3093194 BCB01_000045 COc1cc(NN2C3C(C=CC2C(O)C4CCC(CC4)C(=C)C)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C08 compound treatment 8.5140458E7 -1.74E7 -1.51 8.7903389E7 -1.44E7 -1.26 -1.9535 -0.9959 3093195 BCB01_000046 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C09 compound treatment 9.1677089E7 -1.09E7 -0.94 8.463107E7 -1.76E7 -1.54 -1.7568 -0.972 3000692 BCB01_000047 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C10 compound treatment 8.9906921E7 -1.27E7 -1.1 9.0670351E7 -1.16E7 -1.01 -1.4912 -0.9993 3093196 BCB01_000048 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C11 compound treatment 7.9117833E7 -2.35E7 -2.03 7.4259037E7 -2.8E7 -2.45 -3.1657 -0.9956 3093197 BCB01_000049 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C12 compound treatment 8.2747386E7 -1.98E7 -1.71 9.2653722E7 -9600000.0 -0.84 -1.8057 -0.9462 3000693 BCB01_000050 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C13 compound treatment 8.955196E7 -1.3E7 -1.13 8.5576484E7 -1.67E7 -1.46 -1.8281 -0.9918 3093198 BCB01_000051 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C14 compound treatment 9.4583617E7 -8000000.0 -0.69 9.4262917E7 -7990000.0 -0.7 -0.9832 -1.0 3000694 BCB01_000052 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C15 compound treatment 9.2863379E7 -9720000.0 -0.84 9.5784298E7 -6470000.0 -0.57 -0.9942 -0.9816 3093199 BCB01_000053 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C16 compound treatment 8.4399625E7 -1.82E7 -1.57 8.5756551E7 -1.65E7 -1.44 -2.1316 -0.9991 3093200 BCB01_000054 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C17 compound treatment 9.3870631E7 -8710000.0 -0.75 9.4157581E7 -8100000.0 -0.71 -1.0333 -0.9995 3000695 BCB01_000055 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C18 compound treatment 9.7061745E7 -5520000.0 -0.48 9.9463538E7 -2790000.0 -0.24 -0.5101 -0.9516 3093201 BCB01_000056 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C19 compound treatment 9.2695371E7 -9890000.0 -0.85 9.656877E7 -5690000.0 -0.5 -0.9559 -0.9669 3093202 BCB01_000057 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C20 compound treatment 1.00201873E8 -2380000.0 -0.21 9.168244E7 -1.06E7 -0.93 -0.7998 -0.8438 3000696 BCB01_000058 COc1ccc(cc1)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C21 compound treatment 1.05473141E8 2890000.0 0.25 1.02026376E8 -228000.0 -0.02 0.1623 0.6485 3093203 BCB01_000059 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C22 compound treatment 9.5777717E7 -6810000.0 -0.59 1.03365281E8 1110000.0 0.1 -0.347 -0.5823 3093204 BCB01_000060 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C23 mock treatment 1.02446562E8 -139000.0 -0.01 9.9827682E7 -2430000.0 -0.21 -0.1587 -0.7459 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 C24 mock treatment 1.09209793E8 6620000.0 0.57 1.0642677E8 4170000.0 0.37 0.6628 0.9765 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D01 mock treatment 9.7574964E7 -5010000.0 -0.43 1.06113217E8 3860000.0 0.34 -0.0672 -0.1224 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D02 mock treatment 1.00133649E8 -2450000.0 -0.21 1.03158623E8 904000.0 0.08 -0.0938 -0.4148 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D03 compound treatment 1.00428289E8 -2160000.0 -0.19 9.6279269E7 -5970000.0 -0.52 -0.5015 -0.9034 3000697 BCB01_000061 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccc(O)c4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D04 compound treatment 8.6645939E7 -1.59E7 -1.38 7.7941933E7 -2.43E7 -2.13 -2.478 -0.9778 3093205 BCB01_000062 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D05 compound treatment 8.8632403E7 -1.4E7 -1.21 9.6654556E7 -5600000.0 -0.49 -1.1987 -0.9214 3093206 BCB01_000063 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)B(O)O)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D06 compound treatment 9.4700844E7 -7880000.0 -0.68 9.6507256E7 -5750000.0 -0.5 -0.8372 -0.9889 3000698 BCB01_000064 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D07 compound treatment 9.4002705E7 -8580000.0 -0.74 9.2648291E7 -9610000.0 -0.84 -1.1186 -0.998 3093207 BCB01_000065 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cn(C(=O)C)c5ccccc45)C(=O)N(C3=O)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D08 compound treatment 8.3796382E7 -1.88E7 -1.62 8.2879107E7 -1.94E7 -1.7 -2.3466 -0.9998 3000792 BCB01_000066 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D09 compound treatment 9.3885814E7 -8700000.0 -0.75 9.0892745E7 -1.14E7 -0.99 -1.2344 -0.9905 3000794 BCB01_000067 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(C)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D10 compound treatment 8.4458303E7 -1.81E7 -1.57 8.8045098E7 -1.42E7 -1.24 -1.9864 -0.9935 3000796 BCB01_000068 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D11 compound treatment 9.4126399E7 -8460000.0 -0.73 9.5975444E7 -6280000.0 -0.55 -0.9052 -0.9901 3000797 BCB01_000069 CC(C)c1ccc(NN2C3C(C=CC2C(O)CC(C)c4ccc(C)o4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D12 compound treatment 8.658145E7 -1.6E7 -1.38 8.2397401E7 -1.99E7 -1.74 -2.2063 -0.9936 3093208 BCB01_000070 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4c(F)cccc4Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D13 compound treatment 8.3740482E7 -1.88E7 -1.63 9.292528E7 -9330000.0 -0.82 -1.7283 -0.9491 3093209 BCB01_000071 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccs4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D14 compound treatment 8.8238587E7 -1.43E7 -1.24 8.9124622E7 -1.31E7 -1.15 -1.6887 -0.9993 3000798 BCB01_000072 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D15 compound treatment 9.6442928E7 -6140000.0 -0.53 9.2132389E7 -1.01E7 -0.89 -1.0015 -0.97 3093210 BCB01_000073 CC(C)c1ccc(NN2C3C(C=CC2C(O)Cc4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D16 compound treatment 8.4827949E7 -1.78E7 -1.53 8.9650217E7 -1.26E7 -1.1 -1.8645 -0.9869 3000800 BCB01_000074 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D17 compound treatment 9.2365155E7 -1.02E7 -0.88 9.1906249E7 -1.03E7 -0.91 -1.2646 -0.9999 3093211 BCB01_000075 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D18 compound treatment 9.3519606E7 -9070000.0 -0.78 7.9919149E7 -2.23E7 -1.95 -1.9359 -0.9193 3000876 BCB01_000076 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c(C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D19 compound treatment 1.01975602E8 -610000.0 -0.05 1.00187038E8 -2070000.0 -0.18 -0.1652 -0.8766 3000877 BCB01_000077 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc5OCOc5c4)C(=O)N(C3=O)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D20 compound treatment 9.022796E7 -1.24E7 -1.07 9.7868075E7 -4390000.0 -0.38 -1.0262 -0.9047 3000878 BCB01_000078 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D21 compound treatment 1.05457121E8 2870000.0 0.25 1.04584558E8 2330000.0 0.2 0.3196 0.9953 3000880 BCB01_000079 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4=C[C@H]5C[C@@H](C4)C5(C)C)C(=O)N(C3=O)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D22 compound treatment 9.7900869E7 -4680000.0 -0.4 8.7594242E7 -1.47E7 -1.28 -1.1933 -0.887 3093212 BCB01_000080 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D23 mock treatment 9.8536309E7 -4050000.0 -0.35 1.05455473E8 3200000.0 0.28 -0.0492 -0.1098 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 D24 mock treatment 1.04790227E8 2200000.0 0.19 1.06837346E8 4580000.0 0.4 0.4183 0.942 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E01 mock treatment 1.03889173E8 1300000.0 0.11 1.0236137E8 107000.0 0.01 0.0863 0.7634 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E02 mock treatment 9.9918685E7 -2670000.0 -0.23 1.03005764E8 752000.0 0.07 -0.1164 -0.4858 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E03 compound treatment 9.3373181E7 -9210000.0 -0.8 9.4259661E7 -7990000.0 -0.7 -1.0574 -0.9979 3000882 BCB01_000081 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E04 compound treatment 9.4033484E7 -8550000.0 -0.74 9.8542007E7 -3710000.0 -0.32 -0.752 -0.9319 3093213 BCB01_000082 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E05 compound treatment 9.0612022E7 -1.2E7 -1.03 9.7431241E7 -4820000.0 -0.42 -1.0297 -0.9219 3093214 BCB01_000083 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E06 compound treatment 9.194648E7 -1.06E7 -0.92 9.3554305E7 -8700000.0 -0.76 -1.1882 -0.9956 3000884 BCB01_000084 CN1C(=O)C2C=CC(C(O)C3CCC(CC3)C(=C)C)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E07 compound treatment 9.3977044E7 -8610000.0 -0.74 9.54921E7 -6760000.0 -0.59 -0.9442 -0.9936 3093215 BCB01_000085 CN1C(=O)C2C=CC(C(O)c3ccco3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E08 compound treatment 9.089603E7 -1.17E7 -1.01 8.9483231E7 -1.28E7 -1.12 -1.5043 -0.9987 3093216 BCB01_000086 CCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E09 compound treatment 9.0981838E7 -1.16E7 -1.0 9.1268E7 -1.1E7 -0.96 -1.3886 -0.9998 3000885 BCB01_000087 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E10 compound treatment 8.9833103E7 -1.28E7 -1.1 9.3080638E7 -9170000.0 -0.8 -1.3465 -0.9879 3093283 BCB01_000088 CCCCCCCCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E11 compound treatment 8.8335425E7 -1.43E7 -1.23 9.22127E7 -1.0E7 -0.88 -1.4917 -0.9864 3093284 BCB01_000089 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E12 compound treatment 8.4104616E7 -1.85E7 -1.6 9.1677495E7 -1.06E7 -0.93 -1.7832 -0.9664 3000886 BCB01_000090 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E13 compound treatment 9.1040431E7 -1.15E7 -1.0 9.3628914E7 -8630000.0 -0.75 -1.2389 -0.9906 3093285 BCB01_000091 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E14 compound treatment 8.8330727E7 -1.43E7 -1.23 8.9769393E7 -1.25E7 -1.09 -1.6432 -0.9982 3093286 BCB01_000092 COc1ccc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c5ccccc15 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E15 compound treatment 9.4176595E7 -8410000.0 -0.73 9.8053488E7 -4200000.0 -0.37 -0.7735 -0.9502 3000889 BCB01_000093 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E16 compound treatment 9.16803E7 -1.09E7 -0.94 9.410302E7 -8150000.0 -0.71 -1.1705 -0.9906 3093287 BCB01_000094 COc1cc(Br)cc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E17 compound treatment 1.00504172E8 -2080000.0 -0.18 1.01764395E8 -490000.0 -0.04 -0.1574 -0.8518 3093288 BCB01_000095 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E18 compound treatment 1.00766992E8 -1820000.0 -0.16 1.04124001E8 1870000.0 0.16 0.0046 0.0205 3000890 BCB01_000096 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3N5CCCCC5)C(=O)N(C)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E19 compound treatment 9.8680749E7 -3900000.0 -0.34 9.8564266E7 -3690000.0 -0.32 -0.4668 -0.9998 3093289 BCB01_000097 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E20 compound treatment 9.5571405E7 -7010000.0 -0.61 9.638664E7 -5870000.0 -0.51 -0.7915 -0.9966 3093290 BCB01_000098 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E21 compound treatment 9.8597674E7 -3990000.0 -0.34 1.00887168E8 -1370000.0 -0.12 -0.3282 -0.9 3000891 BCB01_000099 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E22 compound treatment 1.00566061E8 -2020000.0 -0.17 1.02054067E8 -200000.0 -0.02 -0.1357 -0.7742 3093291 BCB01_000100 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E23 mock treatment 9.9159739E7 -3430000.0 -0.3 1.03944005E8 1690000.0 0.15 -0.1047 -0.3164 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 E24 mock treatment 1.04413747E8 1830000.0 0.16 1.03384206E8 1130000.0 0.1 0.1816 0.9746 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F01 mock treatment 1.04549707E8 1960000.0 0.17 1.03256979E8 1000000.0 0.09 0.182 0.953 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F02 mock treatment 9.9790477E7 -2800000.0 -0.24 9.7075352E7 -5180000.0 -0.45 -0.4912 -0.9565 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F03 compound treatment 9.4900002E7 -7690000.0 -0.66 9.5908981E7 -6350000.0 -0.56 -0.8621 -0.9961 3093292 BCB01_000101 CC(C)c1ccc(NN2C3C(C=CC2C(O)/C=C(\C)/CCC=C(C)C)C(=O)N(C3=O)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F04 compound treatment 9.5135728E7 -7450000.0 -0.64 9.2693467E7 -9560000.0 -0.84 -1.0467 -0.9916 3000892 BCB01_000102 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F05 compound treatment 9.4318196E7 -8270000.0 -0.71 9.8309932E7 -3940000.0 -0.35 -0.749 -0.9444 3093293 BCB01_000103 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F06 compound treatment 8.8124129E7 -1.45E7 -1.25 8.9678823E7 -1.26E7 -1.1 -1.6614 -0.998 3000894 BCB01_000104 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F07 compound treatment 9.3478599E7 -9110000.0 -0.79 1.00023743E8 -2230000.0 -0.2 -0.6942 -0.8566 3093294 BCB01_000105 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F08 compound treatment 8.8745022E7 -1.38E7 -1.2 9.1250685E7 -1.1E7 -0.96 -1.5262 -0.9943 3093295 BCB01_000106 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F09 compound treatment 9.3282365E7 -9300000.0 -0.8 9.5659522E7 -6590000.0 -0.58 -0.9763 -0.9868 3000896 BCB01_000107 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F10 compound treatment 9.060601E7 -1.2E7 -1.03 9.0460442E7 -1.18E7 -1.03 -1.4615 -1.0 3093296 BCB01_000108 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F11 compound treatment 9.154441E7 -1.1E7 -0.95 9.6318891E7 -5940000.0 -0.52 -1.0416 -0.9592 3093297 BCB01_000109 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)C(=O)C)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F12 compound treatment 8.5555581E7 -1.7E7 -1.47 9.3301421E7 -8950000.0 -0.78 -1.5941 -0.9565 3000898 BCB01_000110 CC(C)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F13 compound treatment 6.4882953E7 -3.77E7 -3.26 6.280782E7 -3.94E7 -3.45 -4.7438 -0.9996 3000979 BCB01_000111 CCCCCCCCCCC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F14 compound treatment 8.9497066E7 -1.31E7 -1.13 9.3948198E7 -8310000.0 -0.73 -1.3134 -0.9772 3000980 BCB01_000112 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc(O)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F15 compound treatment 9.5899483E7 -6690000.0 -0.58 9.8024129E7 -4230000.0 -0.37 -0.6701 -0.9769 3000981 BCB01_000113 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F16 compound treatment 9.0374457E7 -1.22E7 -1.05 9.5087767E7 -7170000.0 -0.63 -1.1893 -0.9692 3000982 BCB01_000114 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F17 compound treatment 1.01455205E8 -1130000.0 -0.1 1.02856968E8 603000.0 0.05 -0.0317 -0.2859 3000984 BCB01_000115 COc1ccc(C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O)c4ccccc14 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F18 compound treatment 9.7530593E7 -5060000.0 -0.44 1.01249528E8 -1000000.0 -0.09 -0.3709 -0.8328 3093298 BCB01_000116 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F19 compound treatment 9.5529245E7 -7060000.0 -0.61 9.8681874E7 -3570000.0 -0.31 -0.652 -0.9519 3093299 BCB01_000117 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F20 compound treatment 9.5055575E7 -7530000.0 -0.65 9.7870895E7 -4380000.0 -0.38 -0.7311 -0.9683 3000987 BCB01_000118 CC(=O)N1CC(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F21 compound treatment 9.8142465E7 -4440000.0 -0.38 9.9308072E7 -2950000.0 -0.26 -0.4537 -0.9813 3093300 BCB01_000119 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F22 compound treatment 9.5659478E7 -6930000.0 -0.6 9.9447428E7 -2810000.0 -0.25 -0.5967 -0.9227 3093301 BCB01_000120 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F23 mock treatment 1.03929084E8 1340000.0 0.12 1.0504113E8 2790000.0 0.24 0.2545 0.9423 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 F24 mock treatment 1.02638007E8 52400.0 0.0 1.04432919E8 2180000.0 0.19 0.138 0.7237 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G01 mock treatment 1.00984415E8 -1600000.0 -0.14 1.00961663E8 -1290000.0 -0.11 -0.1778 -0.995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G02 mock treatment 1.02596175E8 10600.0 0.0 1.05157437E8 2900000.0 0.25 0.1803 0.7096 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G03 compound treatment 1.00762226E8 -1820000.0 -0.16 1.01140921E8 -1110000.0 -0.1 -0.1803 -0.9733 3000990 BCB01_000121 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G04 compound treatment 9.7105062E7 -5480000.0 -0.47 9.7478329E7 -4780000.0 -0.42 -0.6303 -0.9981 3093302 BCB01_000122 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G05 compound treatment 9.4780727E7 -7800000.0 -0.67 9.8943513E7 -3310000.0 -0.29 -0.6816 -0.9289 3093303 BCB01_000123 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G06 compound treatment 9.0825393E7 -1.18E7 -1.02 9.6186254E7 -6070000.0 -0.53 -1.0938 -0.9542 3000991 BCB01_000124 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G07 compound treatment 9.3036E7 -9550000.0 -0.82 9.5102072E7 -7150000.0 -0.63 -1.0258 -0.9907 3093304 BCB01_000125 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G08 compound treatment 9.097865E7 -1.16E7 -1.0 9.3647618E7 -8610000.0 -0.75 -1.2415 -0.9901 3000992 BCB01_000126 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G09 compound treatment 9.1497038E7 -1.11E7 -0.96 9.5457969E7 -6800000.0 -0.59 -1.0978 -0.9737 3093373 BCB01_000127 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G10 compound treatment 9.0951976E7 -1.16E7 -1.0 9.0808944E7 -1.14E7 -1.0 -1.4188 -1.0 3093374 BCB01_000128 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G11 compound treatment 8.9519808E7 -1.31E7 -1.13 9.3885821E7 -8370000.0 -0.73 -1.3159 -0.9781 3000993 BCB01_000129 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G12 compound treatment 8.733286E7 -1.53E7 -1.32 9.4582768E7 -7670000.0 -0.67 -1.4063 -0.9511 3093375 BCB01_000130 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(C2C1=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G13 compound treatment 8.7679814E7 -1.49E7 -1.29 9.1901496E7 -1.04E7 -0.91 -1.551 -0.9852 3093376 BCB01_000131 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G14 compound treatment 9.5242222E7 -7340000.0 -0.63 9.3562178E7 -8690000.0 -0.76 -0.9864 -0.9959 3000994 BCB01_000132 C/C=C/C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G15 compound treatment 9.4873518E7 -7710000.0 -0.67 9.4057503E7 -8200000.0 -0.72 -0.9783 -0.9993 3093377 BCB01_000133 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G16 compound treatment 9.2573143E7 -1.0E7 -0.86 9.2590365E7 -9660000.0 -0.85 -1.2095 -0.9999 3000995 BCB01_000134 CCC(CC)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G17 compound treatment 9.6272955E7 -6310000.0 -0.55 9.3355695E7 -8900000.0 -0.78 -0.9362 -0.9848 3093378 BCB01_000135 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G18 compound treatment 9.0319278E7 -1.23E7 -1.06 1.01109768E8 -1140000.0 -0.1 -0.82 -0.7705 3000996 BCB01_000136 CC(C)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G19 compound treatment 9.9884288E7 -2700000.0 -0.23 1.01799234E8 -455000.0 -0.04 -0.1931 -0.816 3093379 BCB01_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G20 compound treatment 9.9254748E7 -3330000.0 -0.29 9.9809616E7 -2440000.0 -0.21 -0.3547 -0.9894 3093380 BCB01_000138 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G21 compound treatment 9.8425107E7 -4160000.0 -0.36 9.2791477E7 -9460000.0 -0.83 -0.8397 -0.9301 3000997 BCB01_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G22 compound treatment 1.00468435E8 -2120000.0 -0.18 1.03665305E8 1410000.0 0.12 -0.042 -0.1902 3093381 BCB01_000140 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G23 mock treatment 1.02514373E8 -71200.0 -0.01 1.02751938E8 498000.0 0.04 0.0265 0.6013 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 G24 mock treatment 1.02219393E8 -366000.0 -0.03 1.01147395E8 -1110000.0 -0.1 -0.0909 -0.8917 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H01 mock treatment 1.05638689E8 3050000.0 0.26 1.05104833E8 2850000.0 0.25 0.3629 0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H02 mock treatment 9.6500849E7 -6080000.0 -0.53 1.00019812E8 -2230000.0 -0.2 -0.5099 -0.9093 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H03 compound treatment 1.02077249E8 -508000.0 -0.04 1.00871639E8 -1380000.0 -0.12 -0.1166 -0.9059 3000998 BCB01_000141 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H04 compound treatment 8.7131614E7 -1.55E7 -1.33 9.2369634E7 -9880000.0 -0.87 -1.5555 -0.978 3093382 BCB01_000142 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H05 compound treatment 9.6249231E7 -6340000.0 -0.55 1.01811131E8 -443000.0 -0.04 -0.4144 -0.7553 3093383 BCB01_000143 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H06 compound treatment 9.1201669E7 -1.14E7 -0.98 9.0454558E7 -1.18E7 -1.03 -1.4255 -0.9997 3000999 BCB01_000144 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(C#N)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H07 compound treatment 9.6109813E7 -6480000.0 -0.56 9.847922E7 -3770000.0 -0.33 -0.6291 -0.9684 3093384 BCB01_000145 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H08 compound treatment 8.7864719E7 -1.47E7 -1.27 9.5345725E7 -6910000.0 -0.6 -1.3266 -0.9422 3093385 BCB01_000146 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H09 compound treatment 9.4382068E7 -8200000.0 -0.71 9.6444711E7 -5810000.0 -0.51 -0.8605 -0.9867 3001000 BCB01_000147 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H10 compound treatment 8.4966859E7 -1.76E7 -1.52 8.8898497E7 -1.34E7 -1.17 -1.9026 -0.9915 3001068 BCB01_000148 CC1(C)[C@H]2CC1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H11 compound treatment 9.3372444E7 -9210000.0 -0.8 9.8812317E7 -3440000.0 -0.3 -0.7757 -0.9116 3001069 BCB01_000149 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H12 compound treatment 8.9987916E7 -1.26E7 -1.09 8.9069268E7 -1.32E7 -1.15 -1.5853 -0.9996 3001070 BCB01_000150 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H13 compound treatment 9.7102984E7 -5480000.0 -0.47 9.9203313E7 -3050000.0 -0.27 -0.5236 -0.9632 3001072 BCB01_000151 C/C=C/C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H14 compound treatment 8.5344881E7 -1.72E7 -1.49 9.3996835E7 -8260000.0 -0.72 -1.564 -0.9449 3093386 BCB01_000152 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H15 compound treatment 9.5316563E7 -7270000.0 -0.63 9.6760689E7 -5490000.0 -0.48 -0.7839 -0.9913 3001073 BCB01_000153 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H16 compound treatment 9.4353675E7 -8230000.0 -0.71 9.2964125E7 -9290000.0 -0.81 -1.0777 -0.9978 3093387 BCB01_000154 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H17 compound treatment 9.8675692E7 -3910000.0 -0.34 1.01422989E8 -831000.0 -0.07 -0.2902 -0.8401 3093388 BCB01_000155 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H18 compound treatment 9.6088249E7 -6500000.0 -0.56 9.6285241E7 -5970000.0 -0.52 -0.7662 -0.9994 3001076 BCB01_000156 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(I)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H19 compound treatment 1.00858017E8 -1730000.0 -0.15 9.9637991E7 -2620000.0 -0.23 -0.2674 -0.9785 3093389 BCB01_000157 CC(C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H20 compound treatment 9.5604679E7 -6980000.0 -0.6 9.6868809E7 -5390000.0 -0.47 -0.7596 -0.9926 3093390 BCB01_000158 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H21 compound treatment 1.03224648E8 639000.0 0.06 1.00395199E8 -1860000.0 -0.16 -0.076 -0.4424 3001078 BCB01_000159 CC(CC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccc(C)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H22 compound treatment 1.01373515E8 -1210000.0 -0.1 9.8849981E7 -3400000.0 -0.3 -0.2847 -0.9015 3093391 BCB01_000160 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H23 mock treatment 9.5685716E7 -6900000.0 -0.6 1.04629972E8 2380000.0 0.21 -0.2744 -0.4347 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 H24 mock treatment 1.04754613E8 2170000.0 0.19 1.03662896E8 1410000.0 0.12 0.2197 0.9794 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I01 mock treatment 1.02041334E8 -544000.0 -0.05 1.05608419E8 3350000.0 0.29 0.1743 0.5864 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I02 mock treatment 9.7654761E7 -4930000.0 -0.43 1.01392397E8 -862000.0 -0.08 -0.3545 -0.8196 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I03 compound treatment 9.6975437E7 -5610000.0 -0.48 1.00325567E8 -1930000.0 -0.17 -0.462 -0.9004 3001079 BCB01_000161 CN1C(=O)C2C=CC(C(O)c3cccc(O)c3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I04 compound treatment 9.5736375E7 -6850000.0 -0.59 9.643368E7 -5820000.0 -0.51 -0.7785 -0.9972 3093392 BCB01_000162 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I05 compound treatment 9.6164069E7 -6420000.0 -0.55 9.9983078E7 -2270000.0 -0.2 -0.5327 -0.9042 3093393 BCB01_000163 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I06 compound treatment 9.0843895E7 -1.17E7 -1.01 9.3106448E7 -9150000.0 -0.8 -1.2832 -0.9931 3001081 BCB01_000164 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I07 compound treatment 9.0804208E7 -1.18E7 -1.02 9.4482224E7 -7770000.0 -0.68 -1.2005 -0.9808 3093394 BCB01_000165 CN1C(=O)C2C=CC(C(O)c3cn(C(=O)C)c4ccccc34)N(Nc5ccccc5)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I08 compound treatment 8.6045804E7 -1.65E7 -1.43 9.2012021E7 -1.02E7 -0.9 -1.644 -0.9748 3093395 BCB01_000166 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I09 compound treatment 9.2040049E7 -1.05E7 -0.91 9.7854651E7 -4400000.0 -0.39 -0.9163 -0.9266 3001082 BCB01_000167 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I10 compound treatment 9.0141095E7 -1.24E7 -1.07 9.4005642E7 -8250000.0 -0.72 -1.2705 -0.9812 3093464 BCB01_000168 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I11 compound treatment 8.8864065E7 -1.37E7 -1.19 9.5231337E7 -7020000.0 -0.61 -1.2726 -0.9532 3001083 BCB01_000169 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I12 compound treatment 8.5770271E7 -1.68E7 -1.45 9.0411914E7 -1.18E7 -1.04 -1.7598 -0.9863 3093465 BCB01_000170 CN1C(=O)C2C=CC(C(O)c3cccn3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I13 compound treatment 9.2825368E7 -9760000.0 -0.84 9.8067784E7 -4190000.0 -0.37 -0.8552 -0.9304 3093466 BCB01_000171 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccc(C)o4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I14 compound treatment 9.358782E7 -9000000.0 -0.78 9.9347334E7 -2910000.0 -0.25 -0.7294 -0.892 3001084 BCB01_000172 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I15 compound treatment 9.2979562E7 -9610000.0 -0.83 9.7818986E7 -4440000.0 -0.39 -0.8612 -0.9401 3093467 BCB01_000173 CN1C(=O)C2C=CC(C(O)c3cccs3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I16 compound treatment 9.1369253E7 -1.12E7 -0.97 9.8804782E7 -3450000.0 -0.3 -0.8985 -0.8855 3093468 BCB01_000174 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I17 compound treatment 9.4223768E7 -8360000.0 -0.72 9.7457022E7 -4800000.0 -0.42 -0.8076 -0.9667 3001085 BCB01_000175 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I18 compound treatment 9.4006085E7 -8580000.0 -0.74 9.7296546E7 -4960000.0 -0.43 -0.8308 -0.9675 3093469 BCB01_000176 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I19 compound treatment 9.8367285E7 -4220000.0 -0.36 9.9643753E7 -2610000.0 -0.23 -0.4192 -0.9747 3001086 BCB01_000177 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccccc5)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I20 compound treatment 9.6251371E7 -6330000.0 -0.55 9.9306542E7 -2950000.0 -0.26 -0.5693 -0.9411 3093470 BCB01_000178 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I21 compound treatment 9.7734253E7 -4850000.0 -0.42 1.02839174E8 585000.0 0.05 -0.2601 -0.6161 3001087 BCB01_000179 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I22 compound treatment 9.8525893E7 -4060000.0 -0.35 9.9683332E7 -2570000.0 -0.22 -0.407 -0.977 3093471 BCB01_000180 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I23 mock treatment 1.03324564E8 739000.0 0.06 1.02021013E8 -233000.0 -0.02 0.0307 0.4582 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 I24 mock treatment 1.02129273E8 -456000.0 -0.04 1.02406711E8 153000.0 0.01 -0.0184 -0.4429 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J01 mock treatment 1.04841789E8 2260000.0 0.19 1.06393182E8 4140000.0 0.36 0.3939 0.9577 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J02 mock treatment 9.6211058E7 -6370000.0 -0.55 9.9680584E7 -2570000.0 -0.23 -0.5486 -0.9222 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J03 compound treatment 1.01108753E8 -1480000.0 -0.13 1.0294278E8 689000.0 0.06 -0.0476 -0.3373 3093472 BCB01_000181 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J04 compound treatment 9.0299104E7 -1.23E7 -1.06 9.4810712E7 -7440000.0 -0.65 -1.211 -0.9725 3001088 BCB01_000182 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J05 compound treatment 9.0221425E7 -1.24E7 -1.07 9.2730983E7 -9520000.0 -0.83 -1.3445 -0.9925 3093473 BCB01_000183 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J06 compound treatment 8.8483203E7 -1.41E7 -1.22 9.0763518E7 -1.15E7 -1.01 -1.5724 -0.9955 3093474 BCB01_000184 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J07 compound treatment 9.6640907E7 -5940000.0 -0.51 9.9238081E7 -3020000.0 -0.26 -0.5497 -0.9522 3001089 BCB01_000185 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J08 compound treatment 8.8860051E7 -1.37E7 -1.19 9.5207158E7 -7050000.0 -0.62 -1.2744 -0.9536 3001153 BCB01_000186 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J09 compound treatment 9.1879371E7 -1.07E7 -0.92 9.5247681E7 -7010000.0 -0.61 -1.0875 -0.9801 3001154 BCB01_000187 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J10 compound treatment 8.8415995E7 -1.42E7 -1.22 9.2334253E7 -9920000.0 -0.87 -1.4793 -0.9859 3001156 BCB01_000188 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J11 compound treatment 8.3882583E7 -1.87E7 -1.62 9.4581071E7 -7670000.0 -0.67 -1.6171 -0.9244 3001157 BCB01_000189 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J12 compound treatment 8.5944675E7 -1.66E7 -1.44 9.1463375E7 -1.08E7 -0.94 -1.6841 -0.9792 3093475 BCB01_000190 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J13 compound treatment 9.4222734E7 -8360000.0 -0.72 9.6800191E7 -5450000.0 -0.48 -0.8483 -0.9798 3093476 BCB01_000191 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J14 compound treatment 9.0356803E7 -1.22E7 -1.06 9.6639081E7 -5620000.0 -0.49 -1.0944 -0.9394 3001159 BCB01_000192 CCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J15 compound treatment 9.3816284E7 -8770000.0 -0.76 1.00106903E8 -2150000.0 -0.19 -0.6685 -0.8566 3093477 BCB01_000193 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J16 compound treatment 7.776971E7 -2.48E7 -2.14 8.1501707E7 -2.08E7 -1.82 -2.7999 -0.9966 3001160 BCB01_000194 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J17 compound treatment 9.489935E7 -7690000.0 -0.66 1.00296316E8 -1960000.0 -0.17 -0.5906 -0.8614 3093478 BCB01_000195 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J18 compound treatment 8.8927869E7 -1.37E7 -1.18 9.509397E7 -7160000.0 -0.63 -1.2772 -0.9562 3093479 BCB01_000196 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J19 compound treatment 9.5269829E7 -7320000.0 -0.63 1.01201731E8 -1050000.0 -0.09 -0.5119 -0.8017 3001161 BCB01_000197 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J20 compound treatment 9.32825E7 -9300000.0 -0.8 9.8798441E7 -3460000.0 -0.3 -0.782 -0.9109 3093480 BCB01_000198 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J21 compound treatment 9.9038622E7 -3550000.0 -0.31 1.05957318E8 3700000.0 0.32 0.0125 0.0281 3093481 BCB01_000199 CCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J22 compound treatment 9.6006812E7 -6580000.0 -0.57 9.9103136E7 -3150000.0 -0.28 -0.5968 -0.9449 3001163 BCB01_000200 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J23 mock treatment 1.0669759E8 4110000.0 0.36 1.06129414E8 3880000.0 0.34 0.491 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 J24 mock treatment 1.00129628E8 -2460000.0 -0.21 1.02560771E8 307000.0 0.03 -0.131 -0.6128 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K01 mock treatment 1.0542641E8 2840000.0 0.25 1.06939413E8 4690000.0 0.41 0.4634 0.9699 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K02 mock treatment 9.9305722E7 -3280000.0 -0.28 1.03372961E8 1120000.0 0.1 -0.1311 -0.4373 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K03 compound treatment 9.56481E7 -6940000.0 -0.6 9.5771099E7 -6480000.0 -0.57 -0.8249 -0.9996 3093482 BCB01_000201 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K04 compound treatment 8.9970055E7 -1.26E7 -1.09 1.02948252E8 694000.0 0.06 -0.7275 -0.6667 3001164 BCB01_000202 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K05 compound treatment 9.18893E7 -1.07E7 -0.92 9.0641005E7 -1.16E7 -1.02 -1.3719 -0.9989 3093483 BCB01_000203 CN1C(=O)C2C=CC(C(O)/C=C(\C)/CCC=C(C)C)N(Nc3ccccc3)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K06 compound treatment 9.2517285E7 -1.01E7 -0.87 9.9460175E7 -2790000.0 -0.24 -0.7878 -0.8721 3093484 BCB01_000204 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K07 compound treatment 9.7472496E7 -5110000.0 -0.44 1.02765989E8 512000.0 0.04 -0.2806 -0.6321 3000112 BCB01_000205 CN1C(=O)C2C=CC(C(O)C(C)(C)C)N(Nc3ccccc3)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K08 compound treatment 8.7136802E7 -1.54E7 -1.33 9.1447087E7 -1.08E7 -0.95 -1.6123 -0.9858 3000114 BCB01_000206 COc1ccc(cc1)C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K09 compound treatment 9.5693727E7 -6890000.0 -0.6 1.01634378E8 -620000.0 -0.05 -0.4593 -0.7684 3000115 BCB01_000207 CCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K10 compound treatment 8.6699354E7 -1.59E7 -1.37 9.2992404E7 -9260000.0 -0.81 -1.5434 -0.9685 3000116 BCB01_000208 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K11 compound treatment 9.0776333E7 -1.18E7 -1.02 9.1594666E7 -1.07E7 -0.93 -1.3809 -0.999 3000118 BCB01_000209 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K12 compound treatment 8.6052027E7 -1.65E7 -1.43 9.1900834E7 -1.04E7 -0.91 -1.6505 -0.9759 3093485 BCB01_000210 CCCCC(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K13 compound treatment 9.4815476E7 -7770000.0 -0.67 9.4542089E7 -7710000.0 -0.67 -0.9518 -1.0 3093645 BCB01_000211 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K14 compound treatment 9.3548644E7 -9040000.0 -0.78 9.5710095E7 -6540000.0 -0.57 -0.9569 -0.9884 3000120 BCB01_000212 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K15 compound treatment 9.6067198E7 -6520000.0 -0.56 9.928173E7 -2970000.0 -0.26 -0.5821 -0.9385 3093555 BCB01_000213 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K16 compound treatment 9.0093217E7 -1.25E7 -1.08 8.9162993E7 -1.31E7 -1.15 -1.5731 -0.9996 3093556 BCB01_000214 COc1ccc(C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K17 compound treatment 9.8047243E7 -4540000.0 -0.39 1.03645022E8 1390000.0 0.12 -0.1911 -0.4656 3000122 BCB01_000215 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K18 compound treatment 9.5187213E7 -7400000.0 -0.64 1.00579879E8 -1670000.0 -0.15 -0.5555 -0.8473 3093557 BCB01_000216 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K19 compound treatment 9.749808E7 -5090000.0 -0.44 1.0277526E8 521000.0 0.05 -0.2785 -0.6303 3000123 BCB01_000217 OC(C#Cc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K20 compound treatment 9.3808198E7 -8780000.0 -0.76 1.01080631E8 -1170000.0 -0.1 -0.6087 -0.7956 3093558 BCB01_000218 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(C2C1=O)N(c5ccccc5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K21 compound treatment 1.03806929E8 1220000.0 0.11 1.05447027E8 3190000.0 0.28 0.2722 0.9113 3093559 BCB01_000219 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K22 compound treatment 1.00982328E8 -1600000.0 -0.14 1.01155298E8 -1100000.0 -0.1 -0.1659 -0.9841 3000124 BCB01_000220 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K23 mock treatment 1.07588586E8 5000000.0 0.43 9.6055553E7 -6200000.0 -0.54 -0.078 -0.1125 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 K24 mock treatment 1.07252474E8 4670000.0 0.4 1.05306919E8 3050000.0 0.27 0.4739 0.9801 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L01 mock treatment 1.03141068E8 555000.0 0.05 1.0335997E8 1110000.0 0.1 0.1024 0.9476 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L02 mock treatment 9.6902556E7 -5680000.0 -0.49 1.00767409E8 -1490000.0 -0.13 -0.4391 -0.8647 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L03 compound treatment 9.9597778E7 -2990000.0 -0.26 9.4644146E7 -7610000.0 -0.67 -0.6534 -0.9148 3093560 BCB01_000221 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L04 compound treatment 9.4761235E7 -7820000.0 -0.68 1.00589911E8 -1660000.0 -0.15 -0.5809 -0.8402 3093561 BCB01_000222 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L05 compound treatment 9.338749E7 -9200000.0 -0.79 1.0505516E8 2800000.0 0.25 -0.3884 -0.4672 3000127 BCB01_000223 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L06 compound treatment 9.1474389E7 -1.11E7 -0.96 9.1656265E7 -1.06E7 -0.93 -1.3345 -0.9999 3093562 BCB01_000224 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L07 compound treatment 1.00816096E8 -1770000.0 -0.15 9.9271894E7 -2980000.0 -0.26 -0.2926 -0.9675 3093563 BCB01_000225 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L08 compound treatment 8.9148581E7 -1.34E7 -1.16 9.5005415E7 -7250000.0 -0.63 -1.2692 -0.9596 3000128 BCB01_000226 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L09 compound treatment 9.3822407E7 -8760000.0 -0.76 1.04306234E8 2050000.0 0.18 -0.4082 -0.5248 3093564 BCB01_000227 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L10 compound treatment 9.2318118E7 -1.03E7 -0.89 8.5753866E7 -1.65E7 -1.44 -1.6482 -0.9726 3000129 BCB01_000228 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4c(F)cccc4Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L11 compound treatment 9.5069789E7 -7520000.0 -0.65 9.6276009E7 -5980000.0 -0.52 -0.829 -0.9943 3093565 BCB01_000229 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L12 compound treatment 8.9800241E7 -1.28E7 -1.1 9.6803233E7 -5450000.0 -0.48 -1.1182 -0.9295 3093566 BCB01_000230 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L13 compound treatment 9.511021E7 -7480000.0 -0.65 8.2009713E7 -2.02E7 -1.77 -1.7094 -0.9065 3000131 BCB01_000231 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L14 compound treatment 8.8073531E7 -1.45E7 -1.25 9.5829938E7 -6420000.0 -0.56 -1.2839 -0.9346 3093567 BCB01_000232 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L15 compound treatment 9.7750909E7 -4830000.0 -0.42 9.4776032E7 -7480000.0 -0.65 -0.7581 -0.9764 3093568 BCB01_000233 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L16 compound treatment 9.215021E7 -1.04E7 -0.9 8.3821717E7 -1.84E7 -1.61 -1.778 -0.9622 3000133 BCB01_000234 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c(C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L17 compound treatment 9.766172E7 -4920000.0 -0.43 1.0077516E8 -1480000.0 -0.13 -0.3922 -0.8824 3093569 BCB01_000235 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L18 compound treatment 9.2484088E7 -1.01E7 -0.87 9.9672081E7 -2580000.0 -0.23 -0.7767 -0.8618 3000205 BCB01_000236 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L19 compound treatment 1.03247314E8 662000.0 0.06 1.03139123E8 885000.0 0.08 0.0952 0.9888 3000206 BCB01_000237 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L20 compound treatment 9.7300859E7 -5280000.0 -0.46 1.0144638E8 -808000.0 -0.07 -0.3728 -0.807 3000207 BCB01_000238 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L21 compound treatment 9.9594168E7 -2990000.0 -0.26 1.07332275E8 5080000.0 0.44 0.1316 0.2559 3000208 BCB01_000239 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L22 compound treatment 1.02669482E8 83900.0 0.01 9.5579248E7 -6670000.0 -0.58 -0.4079 -0.6983 3093570 BCB01_000240 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L23 mock treatment 1.08338369E8 5750000.0 0.5 1.04388943E8 2130000.0 0.19 0.4835 0.9107 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 L24 mock treatment 1.04628554E8 2040000.0 0.18 9.6213316E7 -6040000.0 -0.53 -0.2491 -0.4469 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M01 mock treatment 1.12444541E8 9860000.0 0.85 8.2989623E7 -1.93E7 -1.69 -0.59 -0.3124 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M02 mock treatment 1.00982942E8 -1600000.0 -0.14 8.0359613E7 -2.19E7 -1.92 -1.4528 -0.7562 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M03 compound treatment 9.3429885E7 -9160000.0 -0.79 1.06097014E8 3840000.0 0.34 -0.3214 -0.374 3000209 BCB01_000241 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M04 compound treatment 9.6899853E7 -5690000.0 -0.49 9.9708528E7 -2550000.0 -0.22 -0.5048 -0.9361 3093571 BCB01_000242 C/C=C/C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M05 compound treatment 1.02539735E8 -45900.0 0.0 1.00275388E8 -1980000.0 -0.17 -0.1253 -0.7231 3093572 BCB01_000243 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M06 compound treatment 8.8289632E7 -1.43E7 -1.23 9.0212967E7 -1.2E7 -1.05 -1.6183 -0.9969 3000211 BCB01_000244 CC(C)C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M07 compound treatment 9.627211E7 -6310000.0 -0.55 1.02649456E8 395000.0 0.03 -0.3611 -0.6609 3093573 BCB01_000245 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M08 compound treatment 9.0022527E7 -1.26E7 -1.09 9.5697484E7 -6560000.0 -0.57 -1.173 -0.9556 3093574 BCB01_000246 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M09 compound treatment 9.3457581E7 -9130000.0 -0.79 8.9789506E7 -1.25E7 -1.09 -1.3289 -0.9873 3000213 BCB01_000247 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M10 compound treatment 8.3201542E7 -1.94E7 -1.67 9.4507301E7 -7750000.0 -0.68 -1.6633 -0.9208 3093575 BCB01_000248 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M11 compound treatment 8.5662749E7 -1.69E7 -1.46 9.5973312E7 -6280000.0 -0.55 -1.4222 -0.9108 3000215 BCB01_000249 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M12 compound treatment 8.8024172E7 -1.46E7 -1.26 8.5733664E7 -1.65E7 -1.45 -1.9117 -0.9976 3093576 BCB01_000250 CC(C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M13 compound treatment 8.8116419E7 -1.45E7 -1.25 9.8171783E7 -4080000.0 -0.36 -1.1363 -0.8742 3093646 BCB01_000251 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M14 compound treatment 8.9617676E7 -1.3E7 -1.12 9.6858694E7 -5400000.0 -0.47 -1.1259 -0.9263 3000219 BCB01_000252 CN1C(=O)C2C=CC(C(O)c3cccs3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M15 compound treatment 9.6562177E7 -6020000.0 -0.52 8.8178241E7 -1.41E7 -1.23 -1.239 -0.9265 3093647 BCB01_000253 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M16 compound treatment 8.2827321E7 -1.98E7 -1.71 9.5531567E7 -6720000.0 -0.59 -1.6227 -0.899 3000221 BCB01_000254 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M17 compound treatment 9.3553277E7 -9030000.0 -0.78 9.9824126E7 -2430000.0 -0.21 -0.702 -0.8682 3093648 BCB01_000255 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M18 compound treatment 9.5929064E7 -6660000.0 -0.57 8.9544075E7 -1.27E7 -1.11 -1.1931 -0.9528 3093649 BCB01_000256 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M19 compound treatment 8.4846287E7 -1.77E7 -1.53 1.02541647E8 287000.0 0.03 -1.0656 -0.6954 3000223 BCB01_000257 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M20 compound treatment 9.2626306E7 -9960000.0 -0.86 9.7508253E7 -4750000.0 -0.42 -0.902 -0.9442 3093650 BCB01_000258 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M21 compound treatment 8.4372058E7 -1.82E7 -1.57 9.0020685E7 -1.22E7 -1.07 -1.8694 -0.9824 3093651 BCB01_000259 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M22 compound treatment 8.5741922E7 -1.68E7 -1.45 7.7354739E7 -2.49E7 -2.18 -2.5696 -0.9807 3000225 BCB01_000260 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M23 mock treatment 1.03274576E8 689000.0 0.06 1.02505208E8 251000.0 0.02 0.0576 0.9083 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 M24 mock treatment 1.07888203E8 5300000.0 0.46 9.7722676E7 -4530000.0 -0.4 0.0434 0.0717 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N01 mock treatment 1.06933081E8 4350000.0 0.38 9.9460944E7 -2790000.0 -0.24 0.0927 0.2068 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N02 mock treatment 9.5188112E7 -7400000.0 -0.64 8.5787042E7 -1.65E7 -1.44 -1.4709 -0.933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N03 compound treatment 9.3037597E7 -9550000.0 -0.82 9.271146E7 -9540000.0 -0.84 -1.1737 -1.0 3093652 BCB01_000261 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N04 compound treatment 8.5956001E7 -1.66E7 -1.44 9.0487123E7 -1.18E7 -1.03 -1.7438 -0.9867 3093653 BCB01_000262 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N05 compound treatment 9.663681E7 -5950000.0 -0.51 9.8350606E7 -3900000.0 -0.34 -0.6049 -0.9803 3000227 BCB01_000263 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N06 compound treatment 9.450557E7 -8080000.0 -0.7 9.4902216E7 -7350000.0 -0.64 -0.9485 -0.9992 3093654 BCB01_000264 C/C=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N07 compound treatment 9.8256227E7 -4330000.0 -0.37 9.3290434E7 -8960000.0 -0.78 -0.8191 -0.9426 3093655 BCB01_000265 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N08 compound treatment 8.387027E7 -1.87E7 -1.62 9.2346078E7 -9910000.0 -0.87 -1.7562 -0.9574 3000229 BCB01_000266 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N09 compound treatment 9.9759082E7 -2830000.0 -0.24 1.0094868E8 -1310000.0 -0.11 -0.2534 -0.9402 3093656 BCB01_000267 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N10 compound treatment 8.8813654E7 -1.38E7 -1.19 8.846514E7 -1.38E7 -1.21 -1.6944 -1.0 3000231 BCB01_000268 CC(C)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N11 compound treatment 8.0519741E7 -2.21E7 -1.91 9.7172939E7 -5080000.0 -0.44 -1.6621 -0.8493 3093657 BCB01_000269 CC(C)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N12 compound treatment 9.2002507E7 -1.06E7 -0.91 9.09505E7 -1.13E7 -0.99 -1.3459 -0.9992 3000297 BCB01_000270 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N13 compound treatment 9.5723675E7 -6860000.0 -0.59 8.8897318E7 -1.34E7 -1.17 -1.2457 -0.9504 3000298 BCB01_000271 OB(O)c1ccc(cc1)C(O)C2C=CC3CN(C(=O)C3N2Nc4ccc(C#N)cc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N14 compound treatment 8.2771432E7 -1.98E7 -1.71 9.4791538E7 -7460000.0 -0.65 -1.672 -0.9127 3000299 BCB01_000272 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N15 compound treatment 9.444607E7 -8140000.0 -0.7 1.00443202E8 -1810000.0 -0.16 -0.6092 -0.8453 3093658 BCB01_000273 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N16 compound treatment 9.1615391E7 -1.1E7 -0.95 8.8643971E7 -1.36E7 -1.19 -1.5123 -0.9936 3093659 BCB01_000274 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N17 compound treatment 8.9694725E7 -1.29E7 -1.11 1.00480445E8 -1770000.0 -0.16 -0.8971 -0.798 3000301 BCB01_000275 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N18 compound treatment 9.2706869E7 -9880000.0 -0.85 9.9778018E7 -2480000.0 -0.22 -0.7566 -0.8594 3093660 BCB01_000276 CC(C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N19 compound treatment 9.9020255E7 -3570000.0 -0.31 9.636216E7 -5890000.0 -0.52 -0.5824 -0.9696 3093661 BCB01_000277 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N20 compound treatment 8.8752732E7 -1.38E7 -1.19 9.6754274E7 -5500000.0 -0.48 -1.1852 -0.9201 3000302 BCB01_000278 CC(CC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C)o4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N21 compound treatment 1.06547305E8 3960000.0 0.34 8.7520558E7 -1.47E7 -1.29 -0.6698 -0.5021 3093662 BCB01_000279 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N22 compound treatment 1.00549261E8 -2040000.0 -0.18 7.6596822E7 -2.57E7 -2.25 -1.7122 -0.7602 3093663 BCB01_000280 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N23 mock treatment 9.5028514E7 -7560000.0 -0.65 1.04755762E8 2500000.0 0.22 -0.3067 -0.4455 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 N24 mock treatment 1.05352642E8 2770000.0 0.24 1.03853352E8 1600000.0 0.14 0.268 0.9675 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O01 mock treatment 1.0540559E8 2820000.0 0.24 8.951696E7 -1.27E7 -1.11 -0.616 -0.5399 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O02 mock treatment 1.02181981E8 -404000.0 -0.03 8.7150734E7 -1.51E7 -1.32 -0.9593 -0.7255 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O03 compound treatment 1.07541805E8 4960000.0 0.43 8.9645259E7 -1.26E7 -1.1 -0.4776 -0.4035 3000303 BCB01_000281 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O04 compound treatment 9.6759848E7 -5830000.0 -0.5 9.6970919E7 -5280000.0 -0.46 -0.6828 -0.9991 3093664 BCB01_000282 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O05 compound treatment 9.9842335E7 -2740000.0 -0.24 1.02205014E8 -49100.0 0.0 -0.1706 -0.7198 3093665 BCB01_000283 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O06 compound treatment 9.8415992E7 -4170000.0 -0.36 9.8331074E7 -3920000.0 -0.34 -0.4974 -0.9997 3000304 BCB01_000284 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O07 compound treatment 1.01076301E8 -1510000.0 -0.13 9.9682666E7 -2570000.0 -0.23 -0.2513 -0.9663 3093666 BCB01_000285 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O08 compound treatment 8.728712E7 -1.53E7 -1.32 9.4085675E7 -8170000.0 -0.71 -1.4398 -0.9584 3093667 BCB01_000286 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)C(=O)C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O09 compound treatment 9.7138634E7 -5450000.0 -0.47 1.02673079E8 419000.0 0.04 -0.3067 -0.65 3000307 BCB01_000287 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O10 compound treatment 9.2751163E7 -9830000.0 -0.85 9.3828702E7 -8430000.0 -0.74 -1.122 -0.9975 3093736 BCB01_000288 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O11 compound treatment 9.676704E7 -5820000.0 -0.5 9.9650021E7 -2600000.0 -0.23 -0.5165 -0.936 3000308 BCB01_000289 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O12 compound treatment 9.3312803E7 -9270000.0 -0.8 9.1468611E7 -1.08E7 -0.94 -1.2338 -0.9967 3093737 BCB01_000290 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O13 compound treatment 8.4105312E7 -1.85E7 -1.6 9.7232518E7 -5020000.0 -0.44 -1.4394 -0.8694 3093738 BCB01_000291 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O14 compound treatment 9.3015237E7 -9570000.0 -0.83 9.3959236E7 -8290000.0 -0.73 -1.0978 -0.9979 3000310 BCB01_000292 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O15 compound treatment 9.3231424E7 -9350000.0 -0.81 9.4451428E7 -7800000.0 -0.68 -1.0542 -0.9965 3093739 BCB01_000293 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O16 compound treatment 9.1135672E7 -1.14E7 -0.99 9.3374412E7 -8880000.0 -0.78 -1.2488 -0.9929 3000311 BCB01_000294 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O17 compound treatment 1.03097762E8 512000.0 0.04 1.02726385E8 472000.0 0.04 0.0605 0.9994 3093740 BCB01_000295 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O18 compound treatment 9.1329127E7 -1.13E7 -0.97 9.9296029E7 -2960000.0 -0.26 -0.8705 -0.8652 3093741 BCB01_000296 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O19 compound treatment 1.02991073E8 405000.0 0.04 1.04614011E8 2360000.0 0.21 0.1708 0.8154 3000313 BCB01_000297 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O20 compound treatment 9.81921E7 -4390000.0 -0.38 1.02344507E8 90400.0 0.01 -0.2627 -0.6922 3093742 BCB01_000298 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O21 compound treatment 1.03529152E8 944000.0 0.08 1.06655122E8 4400000.0 0.39 0.33 0.8382 3000315 BCB01_000299 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O22 compound treatment 1.02511408E8 -74200.0 -0.01 1.01868366E8 -386000.0 -0.03 -0.0284 -0.8266 3093743 BCB01_000300 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)C(C)C)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O23 mock treatment 1.07573078E8 4990000.0 0.43 1.04597158E8 2340000.0 0.21 0.4496 0.9424 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 O24 mock treatment 1.06721067E8 4140000.0 0.36 1.05783499E8 3530000.0 0.31 0.471 0.9974 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P01 mock treatment 9.3014656E7 -9570000.0 -0.83 8.459705E7 -1.77E7 -1.55 -1.6772 -0.957 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P02 mock treatment 1.00056963E8 -2530000.0 -0.22 8.8670449E7 -1.36E7 -1.19 -0.9951 -0.8232 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P03 compound treatment 1.01909283E8 -676000.0 -0.06 8.2882899E7 -1.94E7 -1.7 -1.2401 -0.731 3000135 BCB01_000301 CC(C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P04 compound treatment 1.01082869E8 -1500000.0 -0.13 1.0108502E8 -1170000.0 -0.1 -0.1641 -0.9931 3000137 BCB01_000302 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P05 compound treatment 7.3341744E7 -2.92E7 -2.53 7.0312411E7 -3.19E7 -2.8 -3.7627 -0.9987 3000138 BCB01_000303 CC(CC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P06 compound treatment 9.7056684E7 -5530000.0 -0.48 9.8002819E7 -4250000.0 -0.37 -0.6008 -0.9924 3000139 BCB01_000304 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C#N)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P07 compound treatment 1.0266483E8 79200.0 0.01 1.0245166E8 198000.0 0.02 0.0171 0.9177 3093744 BCB01_000305 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P08 compound treatment 9.3922139E7 -8660000.0 -0.75 9.7008217E7 -5250000.0 -0.46 -0.8538 -0.9725 3000141 BCB01_000306 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P09 compound treatment 9.9648576E7 -2940000.0 -0.25 1.00323266E8 -1930000.0 -0.17 -0.2989 -0.9805 3093745 BCB01_000307 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P10 compound treatment 9.4475151E7 -8110000.0 -0.7 9.7049813E7 -5200000.0 -0.46 -0.8174 -0.9783 3093746 BCB01_000308 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P11 compound treatment 9.7750683E7 -4830000.0 -0.42 9.7154475E7 -5100000.0 -0.45 -0.6109 -0.9994 3000143 BCB01_000309 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P12 compound treatment 9.4290744E7 -8290000.0 -0.72 9.6364351E7 -5890000.0 -0.52 -0.8711 -0.987 3093747 BCB01_000310 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P13 compound treatment 9.0533203E7 -1.21E7 -1.04 8.5230517E7 -1.7E7 -1.49 -1.7896 -0.9846 3093748 BCB01_000311 CC(=CCC/C=C(\C)/C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P14 compound treatment 9.638253E7 -6200000.0 -0.54 9.9005554E7 -3250000.0 -0.28 -0.5799 -0.9561 3000145 BCB01_000312 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P15 compound treatment 8.680451E7 -1.58E7 -1.36 9.1674994E7 -1.06E7 -0.93 -1.6185 -0.9822 3093749 BCB01_000313 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P16 compound treatment 9.5095268E7 -7490000.0 -0.65 9.5549156E7 -6700000.0 -0.59 -0.8724 -0.9988 3093750 BCB01_000314 OCC(O)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P17 compound treatment 1.01873486E8 -712000.0 -0.06 1.00101308E8 -2150000.0 -0.19 -0.1767 -0.8916 3000147 BCB01_000315 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(I)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P18 compound treatment 9.8510248E7 -4080000.0 -0.35 9.8708938E7 -3550000.0 -0.31 -0.4683 -0.998 3093751 BCB01_000316 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P19 compound treatment 1.06463529E8 3880000.0 0.33 1.06835426E8 4580000.0 0.4 0.5204 0.996 3093752 BCB01_000317 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P20 compound treatment 9.8810336E7 -3780000.0 -0.33 1.01887198E8 -367000.0 -0.03 -0.2533 -0.773 3000149 BCB01_000318 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P21 compound treatment 1.01197427E8 -1390000.0 -0.12 1.01965295E8 -289000.0 -0.03 -0.1027 -0.8378 3093752 BCB01_000319 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P22 compound treatment 1.05557812E8 2970000.0 0.26 1.01399737E8 -854000.0 -0.07 0.1287 0.4811 3093753 BCB01_000320 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P23 mock treatment 1.07343189E8 4760000.0 0.41 1.07166408E8 4910000.0 0.43 0.5946 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2000 P24 mock treatment 1.08076042E8 5490000.0 0.47 1.0598677E8 3730000.0 0.33 0.5663 0.9834 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A01 compound treatment 9.4759911E7 -3810000.0 -0.33 9.4704573E7 -1780000.0 -0.16 -0.3433 -0.9418 3000745 BCB02_000001 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A02 compound treatment 1.05313701E8 6740000.0 0.58 9.374562E7 -2740000.0 -0.24 0.2419 0.3842 3000746 BCB02_000002 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A03 compound treatment 9.5920981E7 -2650000.0 -0.23 9.5936142E7 -552000.0 -0.05 -0.1962 -0.8378 3000747 BCB02_000003 OC(C1CCCCC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A04 compound treatment 1.04452861E8 5880000.0 0.51 9.7174878E7 687000.0 0.06 0.4016 0.7853 3000748 BCB02_000004 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A05 compound treatment 9.4883331E7 -3690000.0 -0.32 8.5693415E7 -1.08E7 -0.94 -0.8934 -0.896 3000749 BCB02_000005 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A06 compound treatment 9.6736457E7 -1840000.0 -0.16 9.4553463E7 -1930000.0 -0.17 -0.2319 -0.9995 3000750 BCB02_000006 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A07 compound treatment 9.0189665E7 -8380000.0 -0.72 9.2680724E7 -3810000.0 -0.33 -0.7477 -0.938 3093754 BCB02_000007 CCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A08 compound treatment 1.01507929E8 2930000.0 0.25 9.2687417E7 -3800000.0 -0.33 -0.056 -0.1339 2065163 BCB02_000008 CCOC(=O)/C=C/c1ccccc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A09 compound treatment 9.295416E7 -5620000.0 -0.49 7.9547181E7 -1.69E7 -1.48 -1.3916 -0.892 3093755 BCB02_000009 CCCCCCCCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A10 compound treatment 8.9211856E7 -9360000.0 -0.81 8.9734234E7 -6750000.0 -0.59 -0.9897 -0.9881 3000752 BCB02_000010 CCOC(=O)/C=C/c1cc(F)ccc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A11 compound treatment 9.3897083E7 -4680000.0 -0.4 8.8277566E7 -8210000.0 -0.72 -0.7937 -0.9629 3093756 BCB02_000011 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A12 compound treatment 9.12945E7 -7280000.0 -0.63 8.8940363E7 -7550000.0 -0.66 -0.9117 -0.9997 3000753 BCB02_000012 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A13 compound treatment 8.8723725E7 -9850000.0 -0.85 8.2521713E7 -1.4E7 -1.22 -1.4659 -0.9843 3093757 BCB02_000013 COc1ccc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A14 compound treatment 9.3198883E7 -5370000.0 -0.46 9.1308138E7 -5180000.0 -0.45 -0.6488 -0.9999 3000754 BCB02_000014 CCOC(=O)/C=C/c1cccc(OC)c1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A15 compound treatment 8.7240836E7 -1.13E7 -0.98 9.1810633E7 -4680000.0 -0.41 -0.9816 -0.9252 3093824 BCB02_000015 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A16 compound treatment 9.4395192E7 -4180000.0 -0.36 8.8449648E7 -8040000.0 -0.7 -0.7526 -0.9519 3000755 BCB02_000016 CCOC(=O)/C=C/c1cccc(C)c1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A17 mock treatment 9.5240872E7 -3330000.0 -0.29 8.5695388E7 -1.08E7 -0.94 -0.8714 -0.8825 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A18 mock treatment 8.6105855E7 -1.25E7 -1.08 9.4371619E7 -2120000.0 -0.19 -0.8924 -0.8167 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A19 mock treatment 1.00842767E8 2270000.0 0.2 9.6247734E7 -240000.0 -0.02 0.1237 0.6276 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A20 mock treatment 9.2249759E7 -6320000.0 -0.55 9.3297695E7 -3190000.0 -0.28 -0.5837 -0.9515 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A21 mock treatment 9.5330341E7 -3240000.0 -0.28 8.8869435E7 -7620000.0 -0.67 -0.6696 -0.9258 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A22 mock treatment 9.6732291E7 -1840000.0 -0.16 9.8661683E7 2170000.0 0.19 0.0221 0.089 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A23 mock treatment 9.9848376E7 1270000.0 0.11 1.02152594E8 5660000.0 0.5 0.4284 0.8436 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 A24 mock treatment 9.2503762E7 -6070000.0 -0.52 9.0610088E7 -5880000.0 -0.51 -0.7345 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B01 compound treatment 1.062452E8 7670000.0 0.66 1.0036421E8 3880000.0 0.34 0.7084 0.9516 3093825 BCB02_000017 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B02 compound treatment 8.2077865E7 -1.65E7 -1.42 8.0782032E7 -1.57E7 -1.37 -1.9794 -0.9998 3000756 BCB02_000018 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B03 compound treatment 9.4258716E7 -4310000.0 -0.37 9.2706484E7 -3780000.0 -0.33 -0.4975 -0.9982 3093826 BCB02_000019 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B04 compound treatment 9.466435E7 -3910000.0 -0.34 9.1442013E7 -5050000.0 -0.44 -0.551 -0.9912 3000757 BCB02_000020 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B05 compound treatment 9.673527E7 -1840000.0 -0.16 8.92611E7 -7230000.0 -0.63 -0.5595 -0.858 3093827 BCB02_000021 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(s5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B06 compound treatment 8.9638446E7 -8940000.0 -0.77 8.1434124E7 -1.51E7 -1.32 -1.4773 -0.9675 3093828 BCB02_000022 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B07 compound treatment 9.4195049E7 -4380000.0 -0.38 9.0272521E7 -6220000.0 -0.54 -0.6521 -0.9842 3000758 BCB02_000023 CC(C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B08 compound treatment 9.2211712E7 -6360000.0 -0.55 8.7340654E7 -9150000.0 -0.8 -0.9546 -0.9831 3093829 BCB02_000024 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B09 compound treatment 9.3303032E7 -5270000.0 -0.46 8.8481411E7 -8010000.0 -0.7 -0.8174 -0.9782 3000759 BCB02_000025 CC(CC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(C)o5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B10 compound treatment 8.0132281E7 -1.84E7 -1.59 7.8006834E7 -1.85E7 -1.62 -2.27 -1.0 3093830 BCB02_000026 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B11 compound treatment 8.8843167E7 -9730000.0 -0.84 8.9290581E7 -7200000.0 -0.63 -1.0397 -0.9899 3093831 BCB02_000027 OC(Cc1ccccc1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B12 compound treatment 8.8733014E7 -9840000.0 -0.85 8.5785044E7 -1.07E7 -0.94 -1.2634 -0.9988 3000760 BCB02_000028 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B13 compound treatment 9.1130054E7 -7440000.0 -0.64 9.1361846E7 -5130000.0 -0.45 -0.7718 -0.9845 3093832 BCB02_000029 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B14 compound treatment 8.1410076E7 -1.72E7 -1.48 7.8870118E7 -1.76E7 -1.54 -2.1385 -0.9998 3093833 BCB02_000030 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B15 compound treatment 9.4798459E7 -3770000.0 -0.33 8.9555816E7 -6930000.0 -0.61 -0.6596 -0.9576 3000761 BCB02_000031 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B16 compound treatment 8.4569487E7 -1.4E7 -1.21 8.8550838E7 -7940000.0 -0.69 -1.3465 -0.9653 3093834 BCB02_000032 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B17 mock treatment 9.3931721E7 -4640000.0 -0.4 9.4839173E7 -1650000.0 -0.14 -0.3855 -0.9048 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B18 mock treatment 8.3914427E7 -1.47E7 -1.27 8.3200015E7 -1.33E7 -1.16 -1.7176 -0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B19 mock treatment 9.4088521E7 -4480000.0 -0.39 9.7491013E7 1000000.0 0.09 -0.2119 -0.5334 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B20 mock treatment 8.9371921E7 -9200000.0 -0.79 9.0514128E7 -5970000.0 -0.52 -0.9317 -0.9794 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B21 mock treatment 9.9323874E7 750000.0 0.06 8.6476023E7 -1.0E7 -0.88 -0.5738 -0.653 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B22 mock treatment 8.7316179E7 -1.13E7 -0.97 9.3639427E7 -2850000.0 -0.25 -0.8638 -0.8606 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B23 mock treatment 1.04274329E8 5700000.0 0.49 1.02369644E8 5880000.0 0.51 0.7121 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 B24 mock treatment 1.00202305E8 1630000.0 0.14 9.7095412E7 607000.0 0.05 0.1371 0.9114 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C01 compound treatment 9.6282497E7 -2290000.0 -0.2 9.5148936E7 -1340000.0 -0.12 -0.2228 -0.9688 3093835 BCB02_000033 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C02 compound treatment 1.05391743E8 6820000.0 0.59 9.4641858E7 -1850000.0 -0.16 0.3022 0.4948 3000762 BCB02_000034 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C03 compound treatment 1.00473815E8 1900000.0 0.16 8.5537504E7 -1.1E7 -0.96 -0.5616 -0.5776 3000763 BCB02_000035 Cc1ccccc1C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C04 compound treatment 9.0769411E7 -7800000.0 -0.67 9.0492985E7 -6000000.0 -0.52 -0.8476 -0.9923 3093836 BCB02_000036 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C05 compound treatment 9.8629812E7 56400.0 0.0 8.8046053E7 -8440000.0 -0.74 -0.519 -0.7024 3093837 BCB02_000037 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C06 compound treatment 9.7382397E7 -1190000.0 -0.1 8.8054223E7 -8430000.0 -0.74 -0.5947 -0.7979 3000764 BCB02_000038 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C07 compound treatment 9.3566959E7 -5010000.0 -0.43 8.279122E7 -1.37E7 -1.2 -1.1534 -0.9051 3093838 BCB02_000039 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C08 compound treatment 8.2084221E7 -1.65E7 -1.42 7.4226065E7 -2.23E7 -1.95 -2.3847 -0.9881 3000765 BCB02_000040 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C09 compound treatment 8.749664E7 -1.11E7 -0.96 8.7453109E7 -9040000.0 -0.79 -1.2356 -0.9955 3093839 BCB02_000041 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C10 compound treatment 9.3299738E7 -5270000.0 -0.46 8.4714911E7 -1.18E7 -1.03 -1.0507 -0.9326 3000766 BCB02_000042 O=c1oc2ccccc2cc1C#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C11 compound treatment 9.3731125E7 -4840000.0 -0.42 8.2515367E7 -1.4E7 -1.22 -1.1604 -0.8979 3093840 BCB02_000043 OC(C1CCC=CC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C12 compound treatment 8.6173226E7 -1.24E7 -1.07 8.6873198E7 -9620000.0 -0.84 -1.3524 -0.9929 3000767 BCB02_000044 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C13 compound treatment 9.030531E7 -8270000.0 -0.71 8.9629973E7 -6860000.0 -0.6 -0.9294 -0.9963 3093841 BCB02_000045 CC(=O)n1cc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C14 compound treatment 9.290462E7 -5670000.0 -0.49 8.2620383E7 -1.39E7 -1.21 -1.2044 -0.9203 3000768 BCB02_000046 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C15 compound treatment 9.3160447E7 -5410000.0 -0.47 8.9494159E7 -6990000.0 -0.61 -0.7634 -0.9912 3093842 BCB02_000047 CCCCC(CC)C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C16 compound treatment 9.1117538E7 -7460000.0 -0.64 9.0742403E7 -5750000.0 -0.5 -0.8109 -0.9925 3093843 BCB02_000048 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C17 mock treatment 9.693457E7 -1640000.0 -0.14 8.4973574E7 -1.15E7 -1.01 -0.8127 -0.7986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C18 mock treatment 1.01474802E8 2900000.0 0.25 8.3575683E7 -1.29E7 -1.13 -0.6219 -0.5373 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C19 mock treatment 9.6939581E7 -1630000.0 -0.14 9.4148874E7 -2340000.0 -0.2 -0.2446 -0.9835 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C20 mock treatment 9.7124363E7 -1450000.0 -0.13 9.5075962E7 -1410000.0 -0.12 -0.1759 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C21 mock treatment 9.4011469E7 -4560000.0 -0.39 9.5818783E7 -669000.0 -0.06 -0.32 -0.8034 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C22 mock treatment 1.01955743E8 3380000.0 0.29 8.5422041E7 -1.11E7 -0.97 -0.4782 -0.4728 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C23 mock treatment 1.03661607E8 5090000.0 0.44 9.9916589E7 3430000.0 0.3 0.5229 0.9827 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 C24 mock treatment 1.00345784E8 1770000.0 0.15 1.02406724E8 5920000.0 0.52 0.4745 0.8785 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D01 compound treatment 1.05192238E8 6620000.0 0.57 9.834365E7 1860000.0 0.16 0.5191 0.8734 3000769 BCB02_000049 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D02 compound treatment 1.02558204E8 3980000.0 0.34 8.7702529E7 -8790000.0 -0.77 -0.3003 -0.3565 3093844 BCB02_000050 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D03 compound treatment 9.2659089E7 -5910000.0 -0.51 9.5926743E7 -561000.0 -0.05 -0.396 -0.7716 3093845 BCB02_000051 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D04 compound treatment 9.9530728E7 957000.0 0.08 9.1342355E7 -5150000.0 -0.45 -0.26 -0.5678 3000770 BCB02_000052 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D05 compound treatment 1.00863759E8 2290000.0 0.2 9.0393839E7 -6090000.0 -0.53 -0.2373 -0.4171 3093846 BCB02_000053 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D06 compound treatment 9.1225553E7 -7350000.0 -0.63 8.1409194E7 -1.51E7 -1.32 -1.3819 -0.9437 3000771 BCB02_000054 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D07 compound treatment 9.7897388E7 -676000.0 -0.06 9.1866997E7 -4620000.0 -0.4 -0.3273 -0.8009 3092586 BCB02_000055 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D08 compound treatment 9.2816088E7 -5760000.0 -0.5 9.1692113E7 -4800000.0 -0.42 -0.6484 -0.9964 3092495 BCB02_000056 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D09 compound treatment 9.7067963E7 -1510000.0 -0.13 9.1064026E7 -5420000.0 -0.47 -0.4276 -0.8688 3000772 BCB02_000057 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D10 compound treatment 9.4316136E7 -4260000.0 -0.37 8.4335628E7 -1.22E7 -1.06 -1.0121 -0.8993 3092496 BCB02_000058 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D11 compound treatment 8.6281754E7 -1.23E7 -1.06 9.0027312E7 -6460000.0 -0.57 -1.1505 -0.9565 3092497 BCB02_000059 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D12 compound treatment 9.2226639E7 -6350000.0 -0.55 8.9052754E7 -7440000.0 -0.65 -0.8478 -0.9964 3000773 BCB02_000060 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D13 compound treatment 9.6549879E7 -2020000.0 -0.17 9.5238749E7 -1250000.0 -0.11 -0.2009 -0.9745 3092498 BCB02_000061 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D14 compound treatment 9.4562544E7 -4010000.0 -0.35 8.5927229E7 -1.06E7 -0.92 -0.8985 -0.9103 3000774 BCB02_000062 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D15 compound treatment 8.8455045E7 -1.01E7 -0.87 9.4300068E7 -2190000.0 -0.19 -0.7534 -0.8421 3092499 BCB02_000063 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D16 compound treatment 9.5923809E7 -2650000.0 -0.23 9.3808823E7 -2680000.0 -0.23 -0.3276 -0.9999 3000775 BCB02_000064 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D17 mock treatment 9.3931877E7 -4640000.0 -0.4 8.9631065E7 -6860000.0 -0.6 -0.7078 -0.9808 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D18 mock treatment 9.7530928E7 -1040000.0 -0.09 8.6945951E7 -9540000.0 -0.84 -0.6542 -0.7788 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D19 mock treatment 9.3650546E7 -4920000.0 -0.43 9.5493318E7 -995000.0 -0.09 -0.3622 -0.8346 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D20 mock treatment 9.8249587E7 -324000.0 -0.03 9.3185605E7 -3300000.0 -0.29 -0.2242 -0.7719 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D21 mock treatment 1.03982105E8 5410000.0 0.47 9.7940084E7 1450000.0 0.13 0.4202 0.8679 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D22 mock treatment 9.9152171E7 579000.0 0.05 9.5500976E7 -987000.0 -0.09 -0.0257 -0.258 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D23 mock treatment 1.09644544E8 1.11E7 0.96 9.2339712E7 -4150000.0 -0.36 0.4194 0.4101 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 D24 mock treatment 1.04597054E8 6020000.0 0.52 1.01523872E8 5040000.0 0.44 0.6795 0.9966 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E01 compound treatment 1.09095773E8 1.05E7 0.91 1.00455849E8 3970000.0 0.35 0.8882 0.9129 3092500 BCB02_000065 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E02 compound treatment 1.02728843E8 4160000.0 0.36 9.712536E7 637000.0 0.06 0.2932 0.8073 3000776 BCB02_000066 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E03 compound treatment 9.7212619E7 -1360000.0 -0.12 9.5892636E7 -596000.0 -0.05 -0.12 -0.933 3000847 BCB02_000067 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E04 compound treatment 9.5940742E7 -2630000.0 -0.23 9.3750317E7 -2740000.0 -0.24 -0.3302 -0.9997 3000848 BCB02_000068 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E05 compound treatment 9.5602379E7 -2970000.0 -0.26 9.3268623E7 -3220000.0 -0.28 -0.3807 -0.9989 3000849 BCB02_000069 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(Br)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E06 compound treatment 9.1910166E7 -6660000.0 -0.58 8.9353729E7 -7130000.0 -0.62 -0.8485 -0.9992 3000850 BCB02_000070 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E07 compound treatment 9.5464153E7 -3110000.0 -0.27 8.7478685E7 -9010000.0 -0.79 -0.7474 -0.8973 3000851 BCB02_000071 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E08 compound treatment 9.4336044E7 -4240000.0 -0.37 8.7231463E7 -9260000.0 -0.81 -0.8316 -0.9355 3092501 BCB02_000072 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E09 compound treatment 9.1583076E7 -6990000.0 -0.6 8.95234E7 -6960000.0 -0.61 -0.8579 -1.0 3000852 BCB02_000073 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E10 compound treatment 9.1471915E7 -7100000.0 -0.61 9.439124E7 -2100000.0 -0.18 -0.5635 -0.8801 3092502 BCB02_000074 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E11 compound treatment 9.1001556E7 -7570000.0 -0.65 9.1782675E7 -4710000.0 -0.41 -0.7536 -0.9751 3092503 BCB02_000075 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E12 compound treatment 8.6582406E7 -1.2E7 -1.04 8.7128614E7 -9360000.0 -0.82 -1.3116 -0.9933 3000853 BCB02_000076 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E13 compound treatment 8.9554152E7 -9020000.0 -0.78 8.9879629E7 -6610000.0 -0.58 -0.9598 -0.9892 3092504 BCB02_000077 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E14 compound treatment 9.1867931E7 -6710000.0 -0.58 9.1742493E7 -4750000.0 -0.42 -0.7032 -0.9867 3000854 BCB02_000078 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E15 compound treatment 9.0588137E7 -7990000.0 -0.69 9.1235762E7 -5250000.0 -0.46 -0.8127 -0.9806 3092505 BCB02_000079 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E16 compound treatment 9.7929977E7 -643000.0 -0.06 9.6542338E7 54100.0 0.0 -0.0359 -0.6445 3000855 BCB02_000080 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E17 mock treatment 1.00214468E8 1640000.0 0.14 9.8313294E7 1830000.0 0.16 0.2132 0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E18 mock treatment 1.00817744E8 2240000.0 0.19 9.9457733E7 2970000.0 0.26 0.3208 0.9896 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E19 mock treatment 9.4515043E7 -4060000.0 -0.35 9.5403066E7 -1090000.0 -0.09 -0.315 -0.8674 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E20 mock treatment 9.4330774E7 -4240000.0 -0.37 9.5386947E7 -1100000.0 -0.1 -0.3273 -0.8637 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E21 mock treatment 9.8786378E7 213000.0 0.02 9.7711629E7 1220000.0 0.11 0.0887 0.8166 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E22 mock treatment 9.7213431E7 -1360000.0 -0.12 9.3465245E7 -3020000.0 -0.26 -0.2701 -0.9332 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E23 mock treatment 1.01956532E8 3380000.0 0.29 9.9396373E7 2910000.0 0.25 0.3866 0.9976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 E24 mock treatment 1.0026186E8 1690000.0 0.15 1.00045452E8 3560000.0 0.31 0.3233 0.9403 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F01 compound treatment 1.0241392E8 3840000.0 0.33 9.9018617E7 2530000.0 0.22 0.3911 0.9807 3092506 BCB02_000081 OC(COCc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F02 compound treatment 1.00452331E8 1880000.0 0.16 9.3359114E7 -3130000.0 -0.27 -0.0789 -0.2478 3092507 BCB02_000082 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F03 compound treatment 9.9392385E7 819000.0 0.07 9.4185012E7 -2300000.0 -0.2 -0.0925 -0.4331 3000856 BCB02_000083 COc1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F04 compound treatment 9.6475554E7 -2100000.0 -0.18 9.6090928E7 -397000.0 -0.03 -0.1527 -0.8277 3092508 BCB02_000084 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F05 compound treatment 9.3922882E7 -4650000.0 -0.4 9.3064449E7 -3420000.0 -0.3 -0.4959 -0.9896 3092509 BCB02_000085 CCCCC(O)C1C=CC2C(N1Nc3ccc(OC)cc3)C(=O)N(C4CCCCC4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F06 compound treatment 9.3578497E7 -4990000.0 -0.43 9.2631734E7 -3860000.0 -0.34 -0.5437 -0.9926 3000857 BCB02_000086 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F07 compound treatment 9.6063584E7 -2510000.0 -0.22 9.5585162E7 -903000.0 -0.08 -0.2092 -0.9065 3092510 BCB02_000087 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F08 compound treatment 8.7692336E7 -1.09E7 -0.94 9.0915453E7 -5570000.0 -0.49 -1.0094 -0.9533 3000858 BCB02_000088 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F09 compound treatment 9.405931E7 -4510000.0 -0.39 9.4084837E7 -2400000.0 -0.21 -0.4244 -0.958 3092511 BCB02_000089 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F10 compound treatment 8.3299914E7 -1.53E7 -1.32 8.4790847E7 -1.17E7 -1.02 -1.6567 -0.9921 3000859 BCB02_000090 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F11 compound treatment 9.5912509E7 -2660000.0 -0.23 9.3482552E7 -3010000.0 -0.26 -0.3485 -0.9977 3092512 BCB02_000091 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F12 compound treatment 8.8235309E7 -1.03E7 -0.89 9.4363983E7 -2120000.0 -0.19 -0.7629 -0.8364 3092513 BCB02_000092 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F13 compound treatment 9.8000429E7 -573000.0 -0.05 9.3276612E7 -3210000.0 -0.28 -0.2337 -0.819 3000860 BCB02_000093 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F14 compound treatment 9.0652355E7 -7920000.0 -0.68 9.0814372E7 -5670000.0 -0.5 -0.8349 -0.9876 3092514 BCB02_000094 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F15 compound treatment 9.2421919E7 -6150000.0 -0.53 9.3429388E7 -3060000.0 -0.27 -0.565 -0.9496 3092515 BCB02_000095 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F16 compound treatment 9.4216641E7 -4360000.0 -0.38 9.64801E7 -8100.0 0.0 -0.2666 -0.7084 3000861 BCB02_000096 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F17 mock treatment 1.03091365E8 4520000.0 0.39 1.02031016E8 5540000.0 0.49 0.6189 0.9942 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F18 mock treatment 9.8443074E7 -130000.0 -0.01 9.510488E7 -1380000.0 -0.12 -0.0936 -0.7696 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F19 mock treatment 9.4647933E7 -3930000.0 -0.34 9.5420508E7 -1070000.0 -0.09 -0.3058 -0.8696 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F20 mock treatment 9.2612572E7 -5960000.0 -0.51 9.6420959E7 -67200.0 -0.01 -0.3682 -0.7151 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F21 mock treatment 1.00025846E8 1450000.0 0.13 1.00357344E8 3870000.0 0.34 0.3281 0.9087 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F22 mock treatment 9.6333313E7 -2240000.0 -0.19 9.6267056E7 -221000.0 -0.02 -0.1505 -0.774 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F23 mock treatment 1.01387424E8 2810000.0 0.24 9.9719572E7 3230000.0 0.28 0.3718 0.9972 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 F24 mock treatment 1.00785086E8 2210000.0 0.19 1.02080253E8 5590000.0 0.49 0.4811 0.9158 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G01 compound treatment 9.4762218E7 -3810000.0 -0.33 1.0171535E8 5230000.0 0.46 0.0907 0.1609 3092516 BCB02_000097 CC(C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G02 compound treatment 1.03867693E8 5290000.0 0.46 9.6694801E7 207000.0 0.02 0.3361 0.7345 3000862 BCB02_000098 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G03 compound treatment 9.850496E7 -68500.0 -0.01 9.5193011E7 -1300000.0 -0.11 -0.0843 -0.743 3092587 BCB02_000099 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G04 compound treatment 1.01016449E8 2440000.0 0.21 9.3866871E7 -2620000.0 -0.23 -0.013 -0.0418 3000863 BCB02_000100 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G05 compound treatment 1.0008036E8 1510000.0 0.13 9.3147339E7 -3340000.0 -0.29 -0.1147 -0.3584 3092588 BCB02_000101 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G06 compound treatment 9.9230066E7 657000.0 0.06 9.4766533E7 -1720000.0 -0.15 -0.0664 -0.4127 3092589 BCB02_000102 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G07 compound treatment 9.5782747E7 -2790000.0 -0.24 9.7293827E7 806000.0 0.07 -0.1206 -0.4802 3000864 BCB02_000103 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G08 compound treatment 9.7462778E7 -1110000.0 -0.1 9.1280665E7 -5210000.0 -0.46 -0.3901 -0.8376 3092590 BCB02_000104 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G09 compound treatment 9.6278715E7 -2290000.0 -0.2 8.8350002E7 -8140000.0 -0.71 -0.6438 -0.8708 3092591 BCB02_000105 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G10 compound treatment 1.01301956E8 2730000.0 0.24 9.3584316E7 -2900000.0 -0.25 -0.0131 -0.0377 3000865 BCB02_000106 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G11 compound treatment 9.4251428E7 -4320000.0 -0.37 9.2771494E7 -3720000.0 -0.33 -0.494 -0.9976 3092592 BCB02_000107 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G12 compound treatment 9.6820628E7 -1750000.0 -0.15 9.6347042E7 -141000.0 -0.01 -0.1158 -0.7623 3000866 BCB02_000108 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G13 compound treatment 9.5514324E7 -3060000.0 -0.26 8.869645E7 -7790000.0 -0.68 -0.669 -0.9148 3092593 BCB02_000109 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G14 compound treatment 9.8894275E7 321000.0 0.03 9.4921733E7 -1570000.0 -0.14 -0.0773 -0.553 3000867 BCB02_000110 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G15 compound treatment 9.3631522E7 -4940000.0 -0.43 9.0329935E7 -6160000.0 -0.54 -0.6829 -0.9933 3092594 BCB02_000111 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G16 compound treatment 1.0158246E8 3010000.0 0.26 9.1785568E7 -4700000.0 -0.41 -0.1072 -0.2203 3092595 BCB02_000112 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G17 mock treatment 1.00293084E8 1720000.0 0.15 9.5316116E7 -1170000.0 -0.1 0.0325 0.18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G18 mock treatment 9.4278581E7 -4290000.0 -0.37 8.9861412E7 -6630000.0 -0.58 -0.6724 -0.9767 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G19 mock treatment 9.8752336E7 179000.0 0.02 9.8245155E7 1760000.0 0.15 0.1197 0.7743 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G20 mock treatment 9.810669E7 -467000.0 -0.04 9.5383451E7 -1100000.0 -0.1 -0.0969 -0.9248 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G21 mock treatment 1.01233951E8 2660000.0 0.23 9.497754E7 -1510000.0 -0.13 0.069 0.2603 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G22 mock treatment 9.4749818E7 -3820000.0 -0.33 9.6055126E7 -433000.0 -0.04 -0.2603 -0.7831 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G23 mock treatment 1.03077687E8 4500000.0 0.39 9.2585892E7 -3900000.0 -0.34 0.0336 0.0649 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 G24 mock treatment 1.07971317E8 9400000.0 0.81 1.02797471E8 6310000.0 0.55 0.9644 0.9824 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H01 compound treatment 1.03461336E8 4890000.0 0.42 9.9254629E7 2770000.0 0.24 0.4697 0.9652 3000868 BCB02_000113 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H02 compound treatment 1.03139234E8 4570000.0 0.39 1.00384276E8 3900000.0 0.34 0.52 0.9974 3092596 BCB02_000114 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H03 compound treatment 1.00961853E8 2390000.0 0.21 9.7515464E7 1030000.0 0.09 0.2094 0.9307 3092597 BCB02_000115 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H04 compound treatment 9.5593893E7 -2980000.0 -0.26 9.4123529E7 -2360000.0 -0.21 -0.3283 -0.9942 3000869 BCB02_000116 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H05 compound treatment 9.9554015E7 981000.0 0.08 9.4477274E7 -2010000.0 -0.18 -0.0646 -0.3305 3092598 BCB02_000117 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H06 compound treatment 9.7542468E7 -1030000.0 -0.09 8.6735078E7 -9750000.0 -0.85 -0.6665 -0.7767 3000870 BCB02_000118 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H07 compound treatment 9.9762435E7 1190000.0 0.1 9.6673828E7 186000.0 0.02 0.0841 0.8089 3000871 BCB02_000119 O=c1cccc(o1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H08 compound treatment 9.2210672E7 -6360000.0 -0.55 9.2885169E7 -3600000.0 -0.32 -0.6116 -0.9652 3092599 BCB02_000120 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H09 compound treatment 9.3369561E7 -5200000.0 -0.45 9.7102783E7 615000.0 0.05 -0.2798 -0.6181 3000872 BCB02_000121 COc1cccc(c1)c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H10 compound treatment 9.4881286E7 -3690000.0 -0.32 9.4149885E7 -2340000.0 -0.2 -0.3702 -0.977 3092600 BCB02_000122 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H11 compound treatment 1.00391739E8 1820000.0 0.16 9.6677534E7 189000.0 0.02 0.1228 0.7774 1984103 BCB02_000123 Cc1ccc(cc1)c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H12 compound treatment 9.1904271E7 -6670000.0 -0.58 9.3986659E7 -2500000.0 -0.22 -0.5621 -0.9122 3092601 BCB02_000124 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H13 compound treatment 1.01711865E8 3140000.0 0.27 9.5793037E7 -695000.0 -0.06 0.1487 0.5351 3000873 BCB02_000125 Clc1cccc(c1)c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H14 compound treatment 9.3991144E7 -4580000.0 -0.4 8.7913012E7 -8580000.0 -0.75 -0.8105 -0.9553 3000874 BCB02_000126 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H15 compound treatment 9.8260119E7 -313000.0 -0.03 9.5003533E7 -1480000.0 -0.13 -0.111 -0.8364 3000875 BCB02_000127 Clc1ccccc1c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H16 compound treatment 9.381936E7 -4750000.0 -0.41 9.1287176E7 -5200000.0 -0.46 -0.6122 -0.9987 3092602 BCB02_000128 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H17 mock treatment 9.8605254E7 31800.0 0.0 9.871914E7 2230000.0 0.2 0.14 0.717 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H18 mock treatment 9.2089997E7 -6480000.0 -0.56 9.2850212E7 -3640000.0 -0.32 -0.6211 -0.9642 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H19 mock treatment 1.03809318E8 5240000.0 0.45 1.00583676E8 4100000.0 0.36 0.5732 0.9934 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H20 mock treatment 9.6584096E7 -1990000.0 -0.17 9.637534E7 -113000.0 -0.01 -0.1285 -0.7465 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H21 mock treatment 1.07060253E8 8490000.0 0.73 1.00439444E8 3950000.0 0.35 0.7628 0.9412 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H22 mock treatment 1.00126601E8 1550000.0 0.13 8.929837E7 -7190000.0 -0.63 -0.3501 -0.5441 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H23 mock treatment 1.00969861E8 2400000.0 0.21 9.9086842E7 2600000.0 0.23 0.3072 0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 H24 mock treatment 1.07312192E8 8740000.0 0.75 1.02514115E8 6030000.0 0.53 0.9066 0.9846 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I01 compound treatment 1.08233713E8 9660000.0 0.83 1.02823499E8 6340000.0 0.55 0.9821 0.9803 3092603 BCB02_000129 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I02 compound treatment 1.0338059E8 4810000.0 0.42 9.1748357E7 -4740000.0 -0.41 3.0E-4 5.0E-4 3000947 BCB02_000130 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I03 compound treatment 9.6570952E7 -2000000.0 -0.17 9.9428909E7 2940000.0 0.26 0.0597 0.1925 3000948 BCB02_000131 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I04 compound treatment 9.1841275E7 -6730000.0 -0.58 9.7587109E7 1100000.0 0.1 -0.3432 -0.5822 3000949 BCB02_000132 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I05 compound treatment 9.4878376E7 -3700000.0 -0.32 9.7129349E7 641000.0 0.06 -0.186 -0.574 3000950 BCB02_000133 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I06 compound treatment 9.244782E7 -6130000.0 -0.53 9.0991045E7 -5500000.0 -0.48 -0.7143 -0.9989 3000951 BCB02_000134 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I07 compound treatment 9.6014696E7 -2560000.0 -0.22 9.6493706E7 5510.0 0.0 -0.1559 -0.7056 3092604 BCB02_000135 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I08 compound treatment 8.51156E7 -1.35E7 -1.16 8.4573212E7 -1.19E7 -1.04 -1.5593 -0.9985 3000952 BCB02_000136 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I09 compound treatment 8.6161515E7 -1.24E7 -1.07 9.4361119E7 -2130000.0 -0.19 -0.8897 -0.8177 3092605 BCB02_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I10 compound treatment 9.0762005E7 -7810000.0 -0.67 9.0201223E7 -6290000.0 -0.55 -0.8661 -0.9949 3092606 BCB02_000138 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I11 compound treatment 9.424412E7 -4330000.0 -0.37 9.4086905E7 -2400000.0 -0.21 -0.413 -0.9629 3000953 BCB02_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I12 compound treatment 9.3729647E7 -4840000.0 -0.42 9.4413452E7 -2070000.0 -0.18 -0.4242 -0.9302 3092607 BCB02_000140 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I13 compound treatment 9.4511219E7 -4060000.0 -0.35 9.5054351E7 -1430000.0 -0.13 -0.3368 -0.9039 3092678 BCB02_000141 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I14 compound treatment 9.2808002E7 -5770000.0 -0.5 9.2226783E7 -4260000.0 -0.37 -0.6158 -0.9899 3000954 BCB02_000142 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I15 compound treatment 9.5346622E7 -3230000.0 -0.28 9.4708282E7 -1780000.0 -0.16 -0.3072 -0.9622 3092679 BCB02_000143 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I16 compound treatment 9.425608E7 -4320000.0 -0.37 9.7368119E7 880000.0 0.08 -0.2092 -0.5495 3000955 BCB02_000144 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I17 mock treatment 9.2556877E7 -6020000.0 -0.52 9.5488332E7 -1000000.0 -0.09 -0.4293 -0.8147 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I18 mock treatment 9.3382835E7 -5190000.0 -0.45 9.1616961E7 -4870000.0 -0.43 -0.6185 -0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I19 mock treatment 9.913304E7 560000.0 0.05 9.5214728E7 -1270000.0 -0.11 -0.0446 -0.3674 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I20 mock treatment 9.389644E7 -4680000.0 -0.4 9.672702E7 239000.0 0.02 -0.2709 -0.6696 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I21 mock treatment 9.708546E7 -1490000.0 -0.13 9.8230482E7 1740000.0 0.15 0.0169 0.085 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I22 mock treatment 9.3550341E7 -5020000.0 -0.43 9.5702134E7 -786000.0 -0.07 -0.3554 -0.8091 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I23 mock treatment 1.01136152E8 2560000.0 0.22 9.9879162E7 3390000.0 0.3 0.3664 0.9896 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 I24 mock treatment 1.00751167E8 2180000.0 0.19 1.0017619E8 3690000.0 0.32 0.3612 0.967 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J01 compound treatment 1.06492076E8 7920000.0 0.68 1.01937841E8 5450000.0 0.48 0.8209 0.9845 3000956 BCB02_000145 CCCc1cccc(=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J02 compound treatment 9.9571941E7 998000.0 0.09 9.5789751E7 -698000.0 -0.06 0.0178 0.168 3092680 BCB02_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J03 compound treatment 1.01209176E8 2640000.0 0.23 9.8835816E7 2350000.0 0.21 0.3063 0.9987 3000957 BCB02_000147 Fc1ccc(cc1)c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J04 compound treatment 9.1543589E7 -7030000.0 -0.61 9.4992094E7 -1500000.0 -0.13 -0.5219 -0.8403 3092681 BCB02_000148 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J05 compound treatment 9.9615407E7 1040000.0 0.09 9.773204E7 1240000.0 0.11 0.1406 0.9955 3000958 BCB02_000149 O=c1cccc(o1)c2ccc(C#N)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J06 compound treatment 9.0977235E7 -7600000.0 -0.66 9.355796E7 -2930000.0 -0.26 -0.6453 -0.916 3000959 BCB02_000150 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J07 compound treatment 9.5317507E7 -3260000.0 -0.28 1.01138105E8 4650000.0 0.41 0.0889 0.1797 3092682 BCB02_000151 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J08 compound treatment 9.1368466E7 -7200000.0 -0.62 9.3125778E7 -3360000.0 -0.29 -0.6481 -0.9415 3092683 BCB02_000152 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J09 compound treatment 9.347024E7 -5100000.0 -0.44 9.7389941E7 902000.0 0.08 -0.2559 -0.5714 3000960 BCB02_000153 FC(F)(F)c1ccccc1c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J10 compound treatment 8.6796811E7 -1.18E7 -1.02 8.9218243E7 -7270000.0 -0.64 -1.1691 -0.9745 3092684 BCB02_000154 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J11 compound treatment 9.9707443E7 1130000.0 0.1 9.8592544E7 2100000.0 0.18 0.1995 0.9563 3000961 BCB02_000155 O=c1cccc(o1)c2ccc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J12 compound treatment 8.8171221E7 -1.04E7 -0.9 9.1674616E7 -4810000.0 -0.42 -0.9332 -0.9404 3000962 BCB02_000156 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J13 compound treatment 9.7055068E7 -1520000.0 -0.13 9.8361029E7 1870000.0 0.16 0.0232 0.1103 3092685 BCB02_000157 O=c1cccc(o1)c2ccco2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J14 compound treatment 8.9638487E7 -8930000.0 -0.77 9.4400081E7 -2090000.0 -0.18 -0.6749 -0.851 3092686 BCB02_000158 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J15 compound treatment 9.7672066E7 -901000.0 -0.08 9.725835E7 770000.0 0.07 -0.0074 -0.0718 3000963 BCB02_000159 O=c1cccc(CCc2ccccc2)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J16 compound treatment 8.817823E7 -1.04E7 -0.9 9.2702256E7 -3790000.0 -0.33 -0.8692 -0.9082 3092687 BCB02_000160 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J17 mock treatment 9.6780992E7 -1790000.0 -0.15 9.8011443E7 1520000.0 0.13 -0.0152 -0.0744 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J18 mock treatment 9.138609E7 -7190000.0 -0.62 9.3626773E7 -2860000.0 -0.25 -0.616 -0.9203 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J19 mock treatment 9.8316783E7 -257000.0 -0.02 9.8078558E7 1590000.0 0.14 0.0827 0.5871 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J20 mock treatment 9.4371047E7 -4200000.0 -0.36 9.5277803E7 -1210000.0 -0.11 -0.3316 -0.8769 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J21 mock treatment 9.9473989E7 901000.0 0.08 9.7516737E7 1030000.0 0.09 0.1186 0.9974 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J22 mock treatment 9.337511E7 -5200000.0 -0.45 9.4628111E7 -1860000.0 -0.16 -0.4326 -0.9058 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J23 mock treatment 1.05807279E8 7230000.0 0.62 1.02619738E8 6130000.0 0.54 0.8212 0.9971 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 J24 mock treatment 1.00106485E8 1530000.0 0.13 1.00529407E8 4040000.0 0.35 0.3437 0.9101 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K01 compound treatment 1.0086143E8 2290000.0 0.2 1.0311947E8 6630000.0 0.58 0.5501 0.8973 3000964 BCB02_000161 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K02 compound treatment 9.0645587E7 -7930000.0 -0.68 8.5876885E7 -1.06E7 -0.93 -1.1409 -0.9888 3092688 BCB02_000162 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K03 compound treatment 1.13666757E8 1.51E7 1.3 9.5018437E7 -1470000.0 -0.13 0.8309 0.6343 3092689 BCB02_000163 CC(C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K04 compound treatment 8.7439022E7 -1.11E7 -0.96 9.3737536E7 -2750000.0 -0.24 -0.8503 -0.8576 3000965 BCB02_000164 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K05 compound treatment 1.00968592E8 2400000.0 0.21 9.1362759E7 -5130000.0 -0.45 -0.1709 -0.346 3092690 BCB02_000165 CC(CC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K06 compound treatment 8.9028321E7 -9550000.0 -0.82 8.8386599E7 -8100000.0 -0.71 -1.0843 -0.9972 3000966 BCB02_000166 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K07 compound treatment 9.710868E7 -1460000.0 -0.13 9.5920933E7 -567000.0 -0.05 -0.1246 -0.9165 3092691 BCB02_000167 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K08 compound treatment 9.9507253E7 934000.0 0.08 8.932065E7 -7170000.0 -0.63 -0.3865 -0.6112 3092692 BCB02_000168 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K09 compound treatment 8.398783E7 -1.46E7 -1.26 9.7574444E7 1090000.0 0.1 -0.8236 -0.6519 3000967 BCB02_000169 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K10 compound treatment 8.3170697E7 -1.54E7 -1.33 8.9277624E7 -7210000.0 -0.63 -1.3869 -0.9419 3092693 BCB02_000170 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K11 compound treatment 9.6121331E7 -2450000.0 -0.21 9.4212065E7 -2280000.0 -0.2 -0.2906 -0.9995 3000968 BCB02_000171 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K12 compound treatment 7.5830516E7 -2.27E7 -1.96 8.1051222E7 -1.54E7 -1.35 -2.3443 -0.9833 3092694 BCB02_000172 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K13 compound treatment 9.5954157E7 -2620000.0 -0.23 9.7385726E7 898000.0 0.08 -0.1044 -0.4361 3092695 BCB02_000173 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K14 compound treatment 9.3377493E7 -5200000.0 -0.45 9.8838398E7 2350000.0 0.21 -0.1719 -0.3482 3000969 BCB02_000174 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K15 compound treatment 1.0026314E8 1690000.0 0.15 9.834494E7 1860000.0 0.16 0.2181 0.9986 3092696 BCB02_000175 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K16 compound treatment 9.6157009E7 -2420000.0 -0.21 9.7337972E7 850000.0 0.07 -0.095 -0.4287 3000970 BCB02_000176 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)N(CC)CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K17 mock treatment 1.00821326E8 2250000.0 0.19 9.9225478E7 2740000.0 0.24 0.3067 0.9946 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K18 mock treatment 9.1610599E7 -6960000.0 -0.6 9.592206E7 -566000.0 -0.05 -0.4603 -0.7628 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K19 mock treatment 1.01047706E8 2470000.0 0.21 9.9151486E7 2660000.0 0.23 0.3159 0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K20 mock treatment 9.9879155E7 1310000.0 0.11 9.6787706E7 300000.0 0.03 0.0983 0.8488 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K21 mock treatment 1.00247931E8 1670000.0 0.14 1.02272223E8 5780000.0 0.51 0.4602 0.8742 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K22 mock treatment 9.9955034E7 1380000.0 0.12 9.8595503E7 2110000.0 0.18 0.2148 0.9778 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K23 mock treatment 1.02116239E8 3540000.0 0.31 9.774864E7 1260000.0 0.11 0.2944 0.905 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 K24 mock treatment 1.05107851E8 6530000.0 0.56 9.6627442E7 139000.0 0.01 0.4077 0.7222 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L01 compound treatment 1.05705393E8 7130000.0 0.62 1.00714207E8 4230000.0 0.37 0.6971 0.9702 3000971 BCB02_000177 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L02 compound treatment 9.6294004E7 -2280000.0 -0.2 9.4646273E7 -1840000.0 -0.16 -0.2532 -0.9951 3092697 BCB02_000178 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L03 compound treatment 1.14726342E8 1.62E7 1.4 9.4045557E7 -2440000.0 -0.21 0.8354 0.5919 3000972 BCB02_000179 O=c1cccc(/C=C/c2ccccc2)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L04 compound treatment 9.6906537E7 -1670000.0 -0.14 9.3559914E7 -2930000.0 -0.26 -0.283 -0.9628 3092698 BCB02_000180 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L05 compound treatment 9.5682311E7 -2890000.0 -0.25 9.9065959E7 2580000.0 0.23 -0.0171 -0.0507 3000973 BCB02_000181 O=c1cccc(o1)c2cccc3ccccc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L06 compound treatment 9.5494507E7 -3080000.0 -0.27 8.8978225E7 -7510000.0 -0.66 -0.6528 -0.9207 3092699 BCB02_000182 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L07 compound treatment 9.9985222E7 1410000.0 0.12 9.746321E7 975000.0 0.09 0.1466 0.9848 3000974 BCB02_000183 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L08 compound treatment 9.5312687E7 -3260000.0 -0.28 9.2295742E7 -4190000.0 -0.37 -0.4586 -0.9915 3092700 BCB02_000184 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L09 compound treatment 9.7947093E7 -626000.0 -0.05 1.00758617E8 4270000.0 0.37 0.226 0.5985 3092701 BCB02_000185 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L10 compound treatment 9.2265257E7 -6310000.0 -0.54 9.1001031E7 -5490000.0 -0.48 -0.7248 -0.998 3000975 BCB02_000186 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L11 compound treatment 9.3291089E7 -5280000.0 -0.46 9.5612038E7 -876000.0 -0.08 -0.3768 -0.8145 3092771 BCB02_000187 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L12 compound treatment 8.9369109E7 -9200000.0 -0.8 9.083932E7 -5650000.0 -0.49 -0.9117 -0.9739 3000976 BCB02_000188 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L13 compound treatment 9.1224606E7 -7350000.0 -0.63 9.0833647E7 -5650000.0 -0.49 -0.7988 -0.9924 3092772 BCB02_000189 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L14 compound treatment 9.2121222E7 -6450000.0 -0.56 9.4805384E7 -1680000.0 -0.15 -0.4982 -0.8643 3092773 BCB02_000190 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L15 compound treatment 9.1503881E7 -7070000.0 -0.61 9.0656386E7 -5830000.0 -0.51 -0.7927 -0.996 3000977 BCB02_000191 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L16 compound treatment 9.0777874E7 -7800000.0 -0.67 9.5021773E7 -1470000.0 -0.13 -0.5669 -0.827 3092774 BCB02_000192 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L17 mock treatment 9.7983596E7 -590000.0 -0.05 9.8769154E7 2280000.0 0.2 0.1051 0.5103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L18 mock treatment 9.3716854E7 -4860000.0 -0.42 9.6610929E7 123000.0 0.01 -0.289 -0.6888 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L19 mock treatment 9.7652891E7 -921000.0 -0.08 1.0033385E8 3850000.0 0.34 0.1818 0.5256 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L20 mock treatment 9.8992865E7 419000.0 0.04 9.9455778E7 2970000.0 0.26 0.2093 0.798 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L21 mock treatment 9.8253353E7 -320000.0 -0.03 9.7708353E7 1220000.0 0.11 0.056 0.5073 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L22 mock treatment 9.6735211E7 -1840000.0 -0.16 9.9931558E7 3440000.0 0.3 0.1008 0.296 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L23 mock treatment 1.04510521E8 5940000.0 0.51 8.6868226E7 -9620000.0 -0.84 -0.2327 -0.2361 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 L24 mock treatment 1.04154372E8 5580000.0 0.48 1.02411137E8 5920000.0 0.52 0.7074 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M01 compound treatment 1.07870634E8 9300000.0 0.8 1.02516743E8 6030000.0 0.53 0.9409 0.9792 3000978 BCB02_000193 CC1(C)[C@H]2C[C@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M02 compound treatment 1.0653958E8 7970000.0 0.69 9.2669987E7 -3820000.0 -0.33 0.2502 0.3272 3001047 BCB02_000194 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M03 compound treatment 9.7061829E7 -1510000.0 -0.13 1.02500729E8 6010000.0 0.53 0.2798 0.516 3092775 BCB02_000195 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M04 compound treatment 1.01132719E8 2560000.0 0.22 1.02713355E8 6230000.0 0.54 0.5415 0.9211 3001048 BCB02_000196 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M05 compound treatment 1.0109628E8 2520000.0 0.22 9.4361735E7 -2130000.0 -0.19 0.0225 0.0785 3092776 BCB02_000197 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)[N+](=O)[O-])C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M06 compound treatment 8.8672467E7 -9900000.0 -0.86 8.8470393E7 -8020000.0 -0.7 -1.1009 -0.9952 3001049 BCB02_000198 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M07 compound treatment 1.02233166E8 3660000.0 0.32 9.8748403E7 2260000.0 0.2 0.3634 0.9745 3092777 BCB02_000199 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M08 compound treatment 9.9016466E7 443000.0 0.04 9.0529405E7 -5960000.0 -0.52 -0.3417 -0.6535 3092778 BCB02_000200 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M09 compound treatment 9.3565094E7 -5010000.0 -0.43 1.00708576E8 4220000.0 0.37 -0.0447 -0.0786 3001050 BCB02_000201 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M10 compound treatment 7.6409249E7 -2.22E7 -1.91 7.9657327E7 -1.68E7 -1.47 -2.3952 -0.9916 3001168 BCB02_000202 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M11 compound treatment 9.0725299E7 -7850000.0 -0.68 8.8949706E7 -7540000.0 -0.66 -0.9458 -0.9999 3092779 BCB02_000203 COc1ccc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M12 compound treatment 8.7788599E7 -1.08E7 -0.93 8.5449827E7 -1.1E7 -0.97 -1.3418 -0.9998 3092780 BCB02_000204 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M13 compound treatment 9.679522E7 -1780000.0 -0.15 9.7485493E7 997000.0 0.09 -0.0469 -0.2654 3001169 BCB02_000205 COc1ccc(NN2C3C(C=CC2C(O)C4=CC[C@H](CC4)C(=C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M14 compound treatment 9.0180016E7 -8390000.0 -0.72 8.662983E7 -9860000.0 -0.86 -1.1227 -0.9963 3092781 BCB02_000206 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M15 compound treatment 8.5665027E7 -1.29E7 -1.11 8.3597317E7 -1.29E7 -1.13 -1.5861 -1.0 3001170 BCB02_000207 COc1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M16 mock treatment 9.8382091E7 -191000.0 -0.02 9.3127465E7 -3360000.0 -0.29 -0.2197 -0.7457 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M17 mock treatment 9.0834023E7 -7740000.0 -0.67 9.6292181E7 -196000.0 -0.02 -0.4848 -0.725 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M18 mock treatment 9.6184087E7 -2390000.0 -0.21 8.6826956E7 -9660000.0 -0.85 -0.7438 -0.8546 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M19 mock treatment 9.7705479E7 -868000.0 -0.07 1.01366477E8 4880000.0 0.43 0.2489 0.5742 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M20 mock treatment 8.8155304E7 -1.04E7 -0.9 9.593077E7 -557000.0 -0.05 -0.6708 -0.7443 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M21 mock treatment 1.03996679E8 5420000.0 0.47 9.4369904E7 -2120000.0 -0.19 0.2001 0.3973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M22 mock treatment 9.9385566E7 812000.0 0.07 9.9464728E7 2980000.0 0.26 0.2338 0.8666 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M23 mock treatment 1.00489457E8 1920000.0 0.17 1.01424962E8 4940000.0 0.43 0.4225 0.9132 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 M24 mock treatment 1.03648316E8 5070000.0 0.44 9.5902376E7 -586000.0 -0.05 0.2737 0.6202 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N01 compound treatment 1.07739157E8 9170000.0 0.79 9.6056717E7 -431000.0 -0.04 0.5331 0.6726 3092782 BCB02_000208 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N02 compound treatment 9.2349655E7 -6220000.0 -0.54 1.01080416E8 4590000.0 0.4 -0.0959 -0.1429 3092783 BCB02_000209 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N03 compound treatment 1.02579468E8 4010000.0 0.35 1.00094605E8 3610000.0 0.32 0.4678 0.9989 3001171 BCB02_000210 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N04 compound treatment 9.2742726E7 -5830000.0 -0.5 9.0105225E7 -6380000.0 -0.56 -0.7511 -0.9987 3092784 BCB02_000211 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N05 compound treatment 6.4785402E7 -3.38E7 -2.92 7.89459E7 -1.75E7 -1.54 -3.1492 -0.955 3001172 BCB02_000212 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N06 compound treatment 9.1128805E7 -7440000.0 -0.64 1.00724311E8 4240000.0 0.37 -0.1925 -0.2594 3092785 BCB02_000213 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N07 compound treatment 8.8033471E7 -1.05E7 -0.91 7.9489223E7 -1.7E7 -1.49 -1.6957 -0.9722 3092786 BCB02_000214 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N08 compound treatment 8.4179966E7 -1.44E7 -1.24 9.5625038E7 -863000.0 -0.08 -0.9325 -0.7487 3001173 BCB02_000215 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N09 compound treatment 9.8774758E7 201000.0 0.02 9.8041864E7 1550000.0 0.14 0.1084 0.7911 3092787 BCB02_000216 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N10 compound treatment 9.2327079E7 -6250000.0 -0.54 8.7530783E7 -8960000.0 -0.78 -0.9358 -0.9834 3001174 BCB02_000217 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N11 compound treatment 1.00187754E8 1610000.0 0.14 1.02870158E8 6380000.0 0.56 0.4935 0.8573 3092788 BCB02_000218 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N12 compound treatment 9.257378E7 -6000000.0 -0.52 9.2216151E7 -4270000.0 -0.37 -0.6308 -0.9872 3092789 BCB02_000219 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N13 compound treatment 9.5573583E7 -3000000.0 -0.26 1.00896129E8 4410000.0 0.39 0.0896 0.1927 3001175 BCB02_000220 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N14 compound treatment 9.2855308E7 -5720000.0 -0.49 9.8090133E7 1600000.0 0.14 -0.2501 -0.4871 3092790 BCB02_000221 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N15 compound treatment 9.6708582E7 -1860000.0 -0.16 9.6408829E7 -79400.0 -0.01 -0.1188 -0.7369 3001176 BCB02_000222 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N16 mock treatment 8.4341227E7 -1.42E7 -1.23 8.8520624E7 -7970000.0 -0.7 -1.3623 -0.9639 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N17 mock treatment 1.02663879E8 4090000.0 0.35 9.7819266E7 1330000.0 0.12 0.3322 0.893 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N18 mock treatment 9.0588058E7 -7990000.0 -0.69 9.6663993E7 176000.0 0.02 -0.4768 -0.6912 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N19 mock treatment 9.3265431E7 -5310000.0 -0.46 9.0690691E7 -5800000.0 -0.51 -0.683 -0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N20 mock treatment 9.2738947E7 -5830000.0 -0.5 9.7888967E7 1400000.0 0.12 -0.2697 -0.5199 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N21 mock treatment 1.00813639E8 2240000.0 0.19 9.4836526E7 -1650000.0 -0.14 0.0346 0.1433 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N22 mock treatment 8.8931866E7 -9640000.0 -0.83 9.1807778E7 -4680000.0 -0.41 -0.8785 -0.9466 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N23 mock treatment 1.07483576E8 8910000.0 0.77 1.02400766E8 5910000.0 0.52 0.9101 0.9813 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 N24 mock treatment 1.0225339E8 3680000.0 0.32 1.03371743E8 6880000.0 0.6 0.6507 0.9554 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O01 compound treatment 1.01078068E8 2500000.0 0.22 9.1099789E7 -5390000.0 -0.47 -0.1805 -0.3479 3092791 BCB02_000223 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O02 compound treatment 9.927274E7 699000.0 0.06 9.7788468E7 1300000.0 0.11 0.1232 0.9561 3001177 BCB02_000224 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O03 compound treatment 1.05501977E8 6930000.0 0.6 9.0085288E7 -6400000.0 -0.56 0.0269 0.0328 3092792 BCB02_000225 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)c(OCc5ccccc5)c4)C(=O)N(C6CCCCC6)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O04 compound treatment 9.0792737E7 -7780000.0 -0.67 8.1032412E7 -1.55E7 -1.35 -1.4317 -0.9479 3001178 BCB02_000226 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O05 compound treatment 1.04202943E8 5630000.0 0.49 1.003597E8 3870000.0 0.34 0.5834 0.9844 3092860 BCB02_000227 COc1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O06 compound treatment 1.01939612E8 3370000.0 0.29 9.9729443E7 3240000.0 0.28 0.4062 0.9999 3001179 BCB02_000228 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O07 compound treatment 1.01752552E8 3180000.0 0.27 9.8388727E7 1900000.0 0.17 0.3118 0.9712 3092861 BCB02_000229 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O08 compound treatment 9.1500677E7 -7070000.0 -0.61 8.8503096E7 -7990000.0 -0.7 -0.9261 -0.9978 3001245 BCB02_000230 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O09 compound treatment 1.01143747E8 2570000.0 0.22 9.4189815E7 -2300000.0 -0.2 0.0147 0.0492 3092862 BCB02_000231 COc1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O10 compound treatment 8.8651963E7 -9920000.0 -0.86 8.4480886E7 -1.2E7 -1.05 -1.349 -0.9949 3001246 BCB02_000232 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O11 compound treatment 1.00491095E8 1920000.0 0.17 9.5908037E7 -580000.0 -0.05 0.0812 0.4688 3092863 BCB02_000233 Cc1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O12 compound treatment 9.3030464E7 -5540000.0 -0.48 8.9186051E7 -7300000.0 -0.64 -0.7904 -0.9899 3001247 BCB02_000234 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O13 compound treatment 9.095729E7 -7620000.0 -0.66 8.6640353E7 -9850000.0 -0.86 -1.0746 -0.9911 3092864 BCB02_000235 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O14 compound treatment 8.9354415E7 -9220000.0 -0.8 8.8161317E7 -8330000.0 -0.73 -1.0784 -0.999 3001248 BCB02_000236 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O15 compound treatment 1.00046623E8 1470000.0 0.13 9.4261078E7 -2230000.0 -0.19 -0.0479 -0.2056 3092865 BCB02_000237 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O16 mock treatment 9.4773495E7 -3800000.0 -0.33 9.2551517E7 -3940000.0 -0.34 -0.4757 -0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O17 mock treatment 9.9112706E7 539000.0 0.05 9.7351531E7 863000.0 0.08 0.0864 0.973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O18 mock treatment 9.7766044E7 -807000.0 -0.07 9.6967401E7 479000.0 0.04 -0.0197 -0.2416 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O19 mock treatment 1.04149042E8 5580000.0 0.48 9.9163218E7 2680000.0 0.23 0.5061 0.9451 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O20 mock treatment 9.6638834E7 -1930000.0 -0.17 9.6939904E7 452000.0 0.04 -0.0902 -0.5253 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O21 mock treatment 1.02449437E8 3880000.0 0.33 9.8300569E7 1810000.0 0.16 0.3489 0.9418 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O22 mock treatment 1.00849661E8 2280000.0 0.2 9.9894955E7 3410000.0 0.3 0.3498 0.9796 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O23 mock treatment 1.00980743E8 2410000.0 0.21 1.01924584E8 5440000.0 0.48 0.4835 0.9311 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 O24 mock treatment 1.0921159E8 1.06E7 0.92 1.02027685E8 5540000.0 0.48 0.9925 0.9554 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P01 compound treatment 1.05783643E8 7210000.0 0.62 9.4635615E7 -1850000.0 -0.16 0.3257 0.5061 3001249 BCB02_000238 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P02 compound treatment 9.9523996E7 951000.0 0.08 7.510494E7 -2.14E7 -1.87 -1.2652 -0.6754 3092866 BCB02_000239 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P03 compound treatment 1.02154722E8 3580000.0 0.31 9.8503096E7 2010000.0 0.18 0.3434 0.9645 3001250 BCB02_000240 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P04 compound treatment 9.461555E7 -3960000.0 -0.34 9.5729528E7 -759000.0 -0.07 -0.2887 -0.829 3092867 BCB02_000241 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P05 compound treatment 1.06996666E8 8420000.0 0.73 1.01095696E8 4610000.0 0.4 0.7996 0.9612 3001251 BCB02_000242 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P06 compound treatment 9.714395E7 -1430000.0 -0.12 9.8159943E7 1670000.0 0.15 0.0161 0.0843 3092868 BCB02_000243 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P07 compound treatment 1.03184426E8 4610000.0 0.4 1.00036542E8 3550000.0 0.31 0.5012 0.9924 3001252 BCB02_000244 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P08 compound treatment 9.8462959E7 -110000.0 -0.01 9.0995051E7 -5490000.0 -0.48 -0.3467 -0.721 3092869 BCB02_000245 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P09 compound treatment 1.04872832E8 6300000.0 0.54 9.7167528E7 679000.0 0.06 0.4268 0.7797 3001253 BCB02_000246 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P10 compound treatment 9.4018916E7 -4550000.0 -0.39 9.1638366E7 -4850000.0 -0.42 -0.5783 -0.9993 3092870 BCB02_000247 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P11 compound treatment 1.00304869E8 1730000.0 0.15 9.573603E7 -752000.0 -0.07 0.0592 0.3623 3001254 BCB02_000248 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P12 compound treatment 9.9117012E7 544000.0 0.05 1.0018121E8 3690000.0 0.32 0.2617 0.8014 3092871 BCB02_000249 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P13 compound treatment 1.01323405E8 2750000.0 0.24 9.3108004E7 -3380000.0 -0.3 -0.0412 -0.1087 3001255 BCB02_000250 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P14 compound treatment 9.9111635E7 538000.0 0.05 9.6801265E7 313000.0 0.03 0.0522 0.9682 3092774 BCB02_000251 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P15 compound treatment 9.9772344E7 1200000.0 0.1 9.6126958E7 -361000.0 -0.03 0.0509 0.4698 3092872 BCB02_000252 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P16 mock treatment 9.5970143E7 -2600000.0 -0.22 9.6042018E7 -446000.0 -0.04 -0.1866 -0.8177 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P17 mock treatment 1.05587391E8 7010000.0 0.61 9.9061174E7 2570000.0 0.23 0.5876 0.9092 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P18 mock treatment 1.00910955E8 2340000.0 0.2 9.8635708E7 2150000.0 0.19 0.2757 0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P19 mock treatment 1.04383462E8 5810000.0 0.5 1.00235469E8 3750000.0 0.33 0.5867 0.9787 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P20 mock treatment 1.00988271E8 2410000.0 0.21 9.9164373E7 2680000.0 0.23 0.3131 0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P21 mock treatment 1.0653759E8 7960000.0 0.69 1.01645466E8 5160000.0 0.45 0.8056 0.9791 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P22 mock treatment 1.03280864E8 4710000.0 0.41 1.00966645E8 4480000.0 0.39 0.5646 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P23 mock treatment 1.08411828E8 9840000.0 0.85 1.01248381E8 4760000.0 0.42 0.8955 0.9462 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2088 P24 mock treatment 1.09029582E8 1.05E7 0.9 1.02772024E8 6280000.0 0.55 1.0275 0.9717 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A01 compound treatment 7.98543E7 -1.55E7 -1.34 7.5117407E7 -1.58E7 -1.38 -1.9235 -0.9998 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A02 compound treatment 6.7760496E7 -2.76E7 -2.38 7.1066742E7 -1.99E7 -1.74 -2.9128 -0.9881 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A03 compound treatment 1.00358533E8 5030000.0 0.43 1.00686409E8 9750000.0 0.85 0.9111 0.951 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A04 compound treatment 9.3602137E7 -1720000.0 -0.15 9.0690602E7 -241000.0 -0.02 -0.1201 -0.7993 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A05 compound treatment 8.8059868E7 -7270000.0 -0.63 9.0772849E7 -159000.0 -0.01 -0.4535 -0.7226 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A06 compound treatment 8.5652255E7 -9670000.0 -0.84 7.3992184E7 -1.69E7 -1.48 -1.639 -0.9632 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A07 compound treatment 7.6219683E7 -1.91E7 -1.65 7.164386E7 -1.93E7 -1.69 -2.3605 -0.9999 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A08 compound treatment 9.6181233E7 856000.0 0.07 9.262896E7 1700000.0 0.15 0.1573 0.9481 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A09 compound treatment 9.053042E7 -4790000.0 -0.41 9.3513705E7 2580000.0 0.23 -0.133 -0.282 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A10 compound treatment 8.2764914E7 -1.26E7 -1.08 7.7027577E7 -1.39E7 -1.22 -1.6275 -0.9984 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A11 compound treatment 9.7832541E7 2510000.0 0.22 9.3798368E7 2870000.0 0.25 0.3306 0.9973 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A12 compound treatment 8.8475444E7 -6850000.0 -0.59 8.7999177E7 -2930000.0 -0.26 -0.5998 -0.9301 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A13 mock treatment 9.044245E7 -4880000.0 -0.42 9.3383227E7 2450000.0 0.21 -0.1465 -0.3096 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A14 mock treatment 9.8653728E7 3330000.0 0.29 8.5690917E7 -5240000.0 -0.46 -0.121 -0.2236 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A15 compound treatment 6.9821832E7 -2.55E7 -2.2 6.8211775E7 -2.27E7 -1.99 -2.9636 -0.9987 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A16 compound treatment 8.4508803E7 -1.08E7 -0.93 8.3322595E7 -7610000.0 -0.67 -1.1315 -0.9862 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A17 compound treatment 9.5119043E7 -206000.0 -0.02 9.6756191E7 5820000.0 0.51 0.3479 0.682 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A18 compound treatment 8.0037998E7 -1.53E7 -1.32 7.9843321E7 -1.11E7 -0.97 -1.6198 -0.9885 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A19 compound treatment 8.7205534E7 -8120000.0 -0.7 7.9591193E7 -1.13E7 -0.99 -1.1977 -0.9855 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A20 compound treatment 7.6254686E7 -1.91E7 -1.65 7.4916048E7 -1.6E7 -1.4 -2.1558 -0.9968 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A21 compound treatment 9.1082742E7 -4240000.0 -0.37 9.2650024E7 1720000.0 0.15 -0.1528 -0.3856 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A22 compound treatment 1.02018291E8 6690000.0 0.58 9.3098624E7 2170000.0 0.19 0.5429 0.8923 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A23 compound treatment 1.04195422E8 8870000.0 0.77 9.9277863E7 8350000.0 0.73 1.0583 0.9997 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 A24 compound treatment 8.4490102E7 -1.08E7 -0.94 8.481973E7 -6110000.0 -0.53 -1.04 -0.9648 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B01 compound treatment 8.6812401E7 -8510000.0 -0.74 8.6780819E7 -4150000.0 -0.36 -0.7768 -0.9472 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B02 compound treatment 8.9249768E7 -6080000.0 -0.52 9.0109783E7 -822000.0 -0.07 -0.4219 -0.7966 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B03 compound treatment 8.3927617E7 -1.14E7 -0.98 7.9002451E7 -1.19E7 -1.04 -1.4343 -0.9996 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B04 compound treatment 8.7587891E7 -7740000.0 -0.67 8.5052215E7 -5880000.0 -0.51 -0.8364 -0.9917 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B05 compound treatment 9.1448288E7 -3880000.0 -0.33 8.234312E7 -8590000.0 -0.75 -0.7683 -0.9337 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B06 compound treatment 9.0918529E7 -4410000.0 -0.38 9.4491524E7 3560000.0 0.31 -0.0488 -0.0993 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B07 compound treatment 8.3859803E7 -1.15E7 -0.99 8.6557898E7 -4370000.0 -0.38 -0.9709 -0.9145 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B08 compound treatment 7.8924479E7 -1.64E7 -1.42 6.9554913E7 -2.14E7 -1.87 -2.3245 -0.9906 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B09 compound treatment 9.232039E7 -3000000.0 -0.26 8.6549064E7 -4380000.0 -0.38 -0.4547 -0.9819 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B10 compound treatment 7.8972866E7 -1.64E7 -1.41 7.6260552E7 -1.47E7 -1.28 -1.9066 -0.9989 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B11 compound treatment 7.0782893E7 -2.45E7 -2.12 6.3587664E7 -2.73E7 -2.39 -3.1911 -0.9982 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B12 compound treatment 8.2257262E7 -1.31E7 -1.13 7.8856674E7 -1.21E7 -1.06 -1.5454 -0.9995 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B13 mock treatment 9.330982E7 -2020000.0 -0.17 8.651662E7 -4410000.0 -0.39 -0.3963 -0.9352 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B14 mock treatment 9.1676063E7 -3650000.0 -0.32 8.911967E7 -1810000.0 -0.16 -0.335 -0.9495 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B15 compound treatment 9.6541294E7 1220000.0 0.11 9.0329874E7 -602000.0 -0.05 0.037 0.3153 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B16 compound treatment 8.596376E7 -9360000.0 -0.81 8.3652807E7 -7280000.0 -0.64 -1.0222 -0.993 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B17 compound treatment 2.0973816E7 -7.44E7 -6.42 2.0876379E7 -7.01E7 -6.13 -8.8763 -0.9997 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B18 compound treatment 9.0978535E7 -4350000.0 -0.38 9.0134747E7 -797000.0 -0.07 -0.3148 -0.8243 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B19 compound treatment 8.6656787E7 -8670000.0 -0.75 7.7857304E7 -1.31E7 -1.14 -1.3385 -0.9789 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B20 compound treatment 8.3230374E7 -1.21E7 -1.04 8.0938294E7 -9990000.0 -0.87 -1.3571 -0.9961 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B21 compound treatment 9.7150405E7 1830000.0 0.16 9.8641154E7 7710000.0 0.67 0.5886 0.8494 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B22 compound treatment 9.458358E7 -742000.0 -0.06 9.8282786E7 7350000.0 0.64 0.4096 0.6336 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B23 compound treatment 1.06645399E8 1.13E7 0.98 1.06045645E8 1.51E7 1.32 1.6267 0.9889 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 B24 compound treatment 9.0501584E7 -4820000.0 -0.42 8.8599547E7 -2330000.0 -0.2 -0.4389 -0.9461 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C01 compound treatment 6.1534307E7 -3.38E7 -2.92 6.6727228E7 -2.42E7 -2.12 -3.5616 -0.9876 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C02 compound treatment 9.3087624E7 -2240000.0 -0.19 8.7614873E7 -3320000.0 -0.29 -0.3419 -0.9805 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C03 compound treatment 9.0971966E7 -4350000.0 -0.38 8.4933643E7 -6000000.0 -0.52 -0.637 -0.9866 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C04 compound treatment 9.1576871E7 -3750000.0 -0.32 9.0870926E7 -60500.0 -0.01 -0.2327 -0.7186 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C05 compound treatment 9.3881383E7 -1440000.0 -0.12 8.0947494E7 -9980000.0 -0.87 -0.706 -0.7999 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C06 compound treatment 9.9603527E7 4280000.0 0.37 9.1112975E7 182000.0 0.02 0.2725 0.7368 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C07 compound treatment 9.6796226E7 1470000.0 0.13 9.4071852E7 3140000.0 0.27 0.2842 0.9386 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C08 compound treatment 9.6979083E7 1650000.0 0.14 8.6776091E7 -4160000.0 -0.36 -0.1561 -0.3996 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C09 compound treatment 8.9663239E7 -5660000.0 -0.49 7.5820618E7 -1.51E7 -1.32 -1.2809 -0.9085 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C10 compound treatment 7.0393453E7 -2.49E7 -2.15 6.414144E7 -2.68E7 -2.34 -3.1806 -0.9991 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C11 mock treatment 9.5608426E7 283000.0 0.02 8.5219059E7 -5710000.0 -0.5 -0.3362 -0.6717 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C12 mock treatment 9.6096228E7 771000.0 0.07 8.5647609E7 -5280000.0 -0.46 -0.2799 -0.5991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C13 compound treatment 5.9793283E7 -3.55E7 -3.07 5.3817564E7 -3.71E7 -3.25 -4.4669 -0.9996 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C14 compound treatment 8.8679426E7 -6650000.0 -0.57 8.5206274E7 -5730000.0 -0.5 -0.7602 -0.9977 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C15 mock treatment 9.5837012E7 512000.0 0.04 9.15693E7 638000.0 0.06 0.0707 0.9933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C16 mock treatment 9.6899623E7 1570000.0 0.14 8.3386193E7 -7550000.0 -0.66 -0.3708 -0.5499 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C17 compound treatment 5.3805377E7 -4.15E7 -3.59 5.3494159E7 -3.74E7 -3.28 -4.8526 -0.999 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C18 compound treatment 8.4987354E7 -1.03E7 -0.89 8.6692778E7 -4240000.0 -0.37 -0.8937 -0.9243 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C19 compound treatment 7.2942784E7 -2.24E7 -1.93 6.5233694E7 -2.57E7 -2.25 -2.9573 -0.9972 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C20 compound treatment 9.7061543E7 1740000.0 0.15 8.589559E7 -5040000.0 -0.44 -0.2056 -0.4416 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C21 compound treatment 9.4701972E7 -623000.0 -0.05 9.0005725E7 -926000.0 -0.08 -0.0953 -0.9803 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C22 compound treatment 9.5369309E7 44100.0 0.0 1.00303087E8 9370000.0 0.82 0.5827 0.7104 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C23 compound treatment 1.05504369E8 1.02E7 0.88 9.4897787E7 3970000.0 0.35 0.8671 0.9174 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 C24 compound treatment 9.1098063E7 -4230000.0 -0.37 8.1154105E7 -9780000.0 -0.86 -0.8632 -0.9279 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D01 compound treatment 9.7204872E7 1880000.0 0.16 1.01144248E8 1.02E7 0.89 0.7468 0.8221 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D02 compound treatment 9.8951641E7 3630000.0 0.31 8.9556822E7 -1370000.0 -0.12 0.1364 0.4066 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D03 compound treatment 1.00038578E8 4710000.0 0.41 9.2881802E7 1950000.0 0.17 0.4086 0.9255 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D04 compound treatment 8.0888595E7 -1.44E7 -1.25 7.8137083E7 -1.28E7 -1.12 -1.6735 -0.9986 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D05 compound treatment 6.7879316E7 -2.74E7 -2.37 7.1614891E7 -1.93E7 -1.69 -2.8716 -0.9863 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D06 compound treatment 7.4754244E7 -2.06E7 -1.78 6.4921713E7 -2.6E7 -2.28 -2.866 -0.9925 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D07 compound treatment 9.7880396E7 2560000.0 0.22 9.0134589E7 -797000.0 -0.07 0.1067 0.4612 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D08 compound treatment 7.0384608E7 -2.49E7 -2.15 7.0203303E7 -2.07E7 -1.81 -2.806 -0.9963 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D09 compound treatment 5.100039E7 -4.43E7 -3.83 4.6690423E7 -4.42E7 -3.87 -5.4449 -1.0 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D10 compound treatment 9.3732495E7 -1590000.0 -0.14 7.7667931E7 -1.33E7 -1.16 -0.9181 -0.7854 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D11 mock treatment 9.4511592E7 -814000.0 -0.07 8.9952348E7 -979000.0 -0.09 -0.1103 -0.9952 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D12 mock treatment 9.1594146E7 -3730000.0 -0.32 8.7222118E7 -3710000.0 -0.32 -0.4574 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D13 compound treatment 4.4957443E7 -5.04E7 -4.35 2.8206853E7 -6.27E7 -5.49 -6.9578 -0.9934 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D14 compound treatment 8.2244072E7 -1.31E7 -1.13 7.2731524E7 -1.82E7 -1.59 -1.9252 -0.9858 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D15 mock treatment 9.3185555E7 -2140000.0 -0.18 8.9103639E7 -1830000.0 -0.16 -0.2438 -0.9974 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D16 mock treatment 9.2792731E7 -2530000.0 -0.22 8.7006061E7 -3930000.0 -0.34 -0.3976 -0.9762 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D17 compound treatment 7.9905864E7 -1.54E7 -1.33 7.7873805E7 -1.31E7 -1.14 -1.7498 -0.9971 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D18 compound treatment 9.6162893E7 838000.0 0.07 8.5230064E7 -5700000.0 -0.5 -0.3017 -0.5983 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D19 compound treatment 9.7479189E7 2150000.0 0.19 9.1532737E7 601000.0 0.05 0.1688 0.8729 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D20 compound treatment 9.358418E7 -1740000.0 -0.15 9.2701694E7 1770000.0 0.15 0.0032 0.0149 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D21 compound treatment 9.2799674E7 -2530000.0 -0.22 8.2580198E7 -8350000.0 -0.73 -0.6711 -0.8798 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D22 compound treatment 1.04050224E8 8730000.0 0.75 9.1233472E7 302000.0 0.03 0.5516 0.7315 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D23 compound treatment 9.1578125E7 -3750000.0 -0.32 8.4787343E7 -6140000.0 -0.54 -0.6091 -0.9705 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 D24 compound treatment 1.09234549E8 1.39E7 1.2 1.0489042E8 1.4E7 1.22 1.7133 1.0 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E01 mock treatment 1.05482561E8 1.02E7 0.88 9.5893069E7 4960000.0 0.43 0.9274 0.9474 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E02 mock treatment 9.4936048E7 -389000.0 -0.03 9.4579768E7 3650000.0 0.32 0.202 0.6292 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E03 compound treatment 9.905612E7 3730000.0 0.32 9.1066434E7 135000.0 0.01 0.2362 0.7325 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E04 compound treatment 8.3618896E7 -1.17E7 -1.01 7.4559355E7 -1.64E7 -1.43 -1.7281 -0.9854 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E05 compound treatment 9.6508657E7 1180000.0 0.1 9.0369214E7 -562000.0 -0.05 0.0375 0.3304 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E06 compound treatment 9.5446086E7 121000.0 0.01 8.8075505E7 -2860000.0 -0.25 -0.1694 -0.677 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E07 compound treatment 2.9675008E7 -6.57E7 -5.67 2.3946636E7 -6.7E7 -5.86 -8.1549 -0.9999 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E08 compound treatment 8.052465E7 -1.48E7 -1.28 7.0728308E7 -2.02E7 -1.77 -2.1542 -0.9873 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E09 mock treatment 9.0405583E7 -4920000.0 -0.42 8.11051E7 -9830000.0 -0.86 -0.9086 -0.9472 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E10 mock treatment 8.8861201E7 -6460000.0 -0.56 8.1631906E7 -9300000.0 -0.81 -0.9703 -0.9831 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E11 compound treatment 8.6103963E7 -9220000.0 -0.8 7.6881658E7 -1.4E7 -1.23 -1.4326 -0.9779 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E12 compound treatment 8.3985909E7 -1.13E7 -0.98 7.5288555E7 -1.56E7 -1.37 -1.6606 -0.9865 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E13 compound treatment 3.0591639E7 -6.47E7 -5.59 3.1456914E7 -5.95E7 -5.21 -7.6341 -0.9994 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E14 compound treatment 8.6890877E7 -8430000.0 -0.73 8.1834915E7 -9100000.0 -0.8 -1.0781 -0.999 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E15 compound treatment 6.9128433E7 -2.62E7 -2.26 6.1183624E7 -2.97E7 -2.6 -3.4409 -0.9976 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E16 compound treatment 7.777414E7 -1.76E7 -1.52 7.2717831E7 -1.82E7 -1.59 -2.1991 -0.9997 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E17 mock treatment 1.02964104E8 7640000.0 0.66 9.4673E7 3740000.0 0.33 0.6981 0.9477 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E18 mock treatment 1.00734869E8 5410000.0 0.47 9.81471E7 7220000.0 0.63 0.7769 0.989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E19 compound treatment 9.7760353E7 2440000.0 0.21 9.3312425E7 2380000.0 0.21 0.2961 1.0 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E20 compound treatment 9.4935078E7 -390000.0 -0.03 9.3941265E7 3010000.0 0.26 0.1624 0.6117 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E21 compound treatment 1.00137526E8 4810000.0 0.42 9.4132946E7 3200000.0 0.28 0.492 0.9816 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E22 compound treatment 9.73153E7 1990000.0 0.17 9.8078144E7 7150000.0 0.63 0.5638 0.8692 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E23 compound treatment 9.9521021E7 4200000.0 0.36 9.805029E7 7120000.0 0.62 0.6968 0.9668 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 E24 compound treatment 9.1251834E7 -4070000.0 -0.35 9.018755E7 -744000.0 -0.07 -0.2948 -0.824 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F01 mock treatment 1.04831501E8 9510000.0 0.82 1.00236966E8 9310000.0 0.81 1.1565 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F02 mock treatment 9.1735679E7 -3590000.0 -0.31 9.7547918E7 6620000.0 0.58 0.1902 0.2896 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F03 compound treatment 7.5613772E7 -1.97E7 -1.7 6.9055663E7 -2.19E7 -1.91 -2.5576 -0.9983 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F04 compound treatment 8.7919157E7 -7410000.0 -0.64 8.2379057E7 -8550000.0 -0.75 -0.9816 -0.9969 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F05 compound treatment 8.1788842E7 -1.35E7 -1.17 7.9262695E7 -1.17E7 -1.02 -1.5488 -0.9977 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F06 compound treatment 8.8328962E7 -7000000.0 -0.6 8.6083245E7 -4850000.0 -0.42 -0.7273 -0.985 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F07 compound treatment 8.7785871E7 -7540000.0 -0.65 8.0622836E7 -1.03E7 -0.9 -1.0984 -0.9872 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F08 compound treatment 8.1598053E7 -1.37E7 -1.19 8.4716137E7 -6220000.0 -0.54 -1.223 -0.9376 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F09 mock treatment 9.3537504E7 -1790000.0 -0.15 9.0297604E7 -634000.0 -0.06 -0.1484 -0.9045 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F10 mock treatment 8.5611335E7 -9710000.0 -0.84 8.4659343E7 -6270000.0 -0.55 -0.9814 -0.9788 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F11 compound treatment 5.7662439E7 -3.77E7 -3.25 4.5783318E7 -4.51E7 -3.95 -5.0942 -0.9953 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F12 compound treatment 9.0554531E7 -4770000.0 -0.41 8.4508147E7 -6420000.0 -0.56 -0.6889 -0.9883 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F13 compound treatment 5.6436956E7 -3.89E7 -3.36 5.654002E7 -3.44E7 -3.01 -4.5034 -0.9985 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F14 compound treatment 7.6341538E7 -1.9E7 -1.64 6.9964846E7 -2.1E7 -1.83 -2.4569 -0.9984 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F15 compound treatment 5.9605461E7 -3.57E7 -3.09 5.7530549E7 -3.34E7 -2.92 -4.2486 -0.9996 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F16 compound treatment 8.0527366E7 -1.48E7 -1.28 7.5038848E7 -1.59E7 -1.39 -1.8873 -0.9991 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F17 mock treatment 1.03808741E8 8480000.0 0.73 9.8060025E7 7130000.0 0.62 0.9593 0.9968 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F18 mock treatment 9.9936094E7 4610000.0 0.4 9.572975E7 4800000.0 0.42 0.5785 0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F19 compound treatment 6.6388484E7 -2.89E7 -2.5 6.3651128E7 -2.73E7 -2.39 -3.4555 -0.9997 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F20 compound treatment 9.6178062E7 853000.0 0.07 9.2570181E7 1640000.0 0.14 0.1535 0.9521 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F21 compound treatment 1.00007901E8 4680000.0 0.4 9.7382725E7 6450000.0 0.56 0.6852 0.9866 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F22 compound treatment 9.6449821E7 1120000.0 0.1 9.7167134E7 6240000.0 0.55 0.4546 0.8201 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F23 compound treatment 8.8571041E7 -6750000.0 -0.58 8.5661027E7 -5270000.0 -0.46 -0.7387 -0.9932 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 F24 compound treatment 1.06313937E8 1.1E7 0.95 1.03218621E8 1.23E7 1.08 1.4315 0.9981 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G01 compound treatment 1.09337537E8 1.4E7 1.21 9.4653E7 3720000.0 0.33 1.0861 0.8666 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G02 compound treatment 9.8650297E7 3330000.0 0.29 9.7655126E7 6720000.0 0.59 0.6192 0.9456 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G03 mock treatment 1.00708362E8 5380000.0 0.46 9.5638936E7 4710000.0 0.41 0.6201 0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G04 mock treatment 9.8692239E7 3370000.0 0.29 9.0344946E7 -586000.0 -0.05 0.1693 0.5734 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G05 compound treatment 9.1207667E7 -4120000.0 -0.36 9.2394562E7 1460000.0 0.13 -0.1609 -0.4258 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G06 compound treatment 8.6598676E7 -8730000.0 -0.75 7.8522406E7 -1.24E7 -1.09 -1.3009 -0.9841 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G07 compound treatment 9.592498E7 600000.0 0.05 9.2139061E7 1210000.0 0.11 0.1114 0.9462 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G08 compound treatment 8.9929706E7 -5400000.0 -0.47 8.2212732E7 -8720000.0 -0.76 -0.8691 -0.972 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G09 compound treatment 9.1671168E7 -3650000.0 -0.32 8.3191145E7 -7740000.0 -0.68 -0.7022 -0.9396 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G10 compound treatment 9.4368961E7 -956000.0 -0.08 9.0360121E7 -571000.0 -0.05 -0.0938 -0.9711 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G11 compound treatment 8.6266652E7 -9060000.0 -0.78 8.3904702E7 -7030000.0 -0.61 -0.9881 -0.9929 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G12 compound treatment 6.8145005E7 -2.72E7 -2.35 5.9215358E7 -3.17E7 -2.78 -3.6227 -0.9965 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G13 compound treatment 3.0662072E7 -6.47E7 -5.59 4.6265842E7 -4.47E7 -3.91 -6.7134 -0.9848 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G14 compound treatment 9.0792929E7 -4530000.0 -0.39 8.339743E7 -7530000.0 -0.66 -0.743 -0.969 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G15 compound treatment 9.0765815E7 -4560000.0 -0.39 8.4668893E7 -6260000.0 -0.55 -0.666 -0.9868 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G16 compound treatment 8.7217783E7 -8110000.0 -0.7 7.9146351E7 -1.18E7 -1.03 -1.2245 -0.9822 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G17 compound treatment 9.7893113E7 2570000.0 0.22 9.403967E7 3110000.0 0.27 0.3492 0.9949 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G18 compound treatment 9.8360399E7 3040000.0 0.26 9.3187979E7 2260000.0 0.2 0.325 0.9902 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G19 mock treatment 9.9464406E7 4140000.0 0.36 8.9034307E7 -1900000.0 -0.17 0.1354 0.3435 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G20 mock treatment 9.6699957E7 1370000.0 0.12 9.5315538E7 4380000.0 0.38 0.3553 0.8845 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G21 compound treatment 1.01143475E8 5820000.0 0.5 9.6756145E7 5820000.0 0.51 0.7158 1.0 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G22 compound treatment 8.6358059E7 -8970000.0 -0.77 7.959779E7 -1.13E7 -0.99 -1.249 -0.9925 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G23 compound treatment 1.0669559E8 1.14E7 0.98 9.5118362E7 4190000.0 0.37 0.9535 0.9097 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 G24 compound treatment 9.2000391E7 -3320000.0 -0.29 8.7150053E7 -3780000.0 -0.33 -0.4371 -0.9975 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H01 compound treatment 8.5266273E7 -1.01E7 -0.87 7.5289606E7 -1.56E7 -1.37 -1.5823 -0.9759 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H02 compound treatment 9.1963114E7 -3360000.0 -0.29 9.3175758E7 2240000.0 0.2 -0.0664 -0.1895 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H03 mock treatment 1.0662298E8 1.13E7 0.98 1.01277685E8 1.03E7 0.91 1.3303 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H04 mock treatment 9.5996533E7 671000.0 0.06 8.9908769E7 -1020000.0 -0.09 -0.0223 -0.209 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H05 compound treatment 7.3884674E7 -2.14E7 -1.85 7.7625432E7 -1.33E7 -1.16 -2.1329 -0.975 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H06 compound treatment 9.0454306E7 -4870000.0 -0.42 8.9554298E7 -1380000.0 -0.12 -0.3827 -0.8745 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H07 compound treatment 7.6760901E7 -1.86E7 -1.6 6.9599076E7 -2.13E7 -1.87 -2.4539 -0.9971 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H08 compound treatment 8.0007879E7 -1.53E7 -1.32 8.046531E7 -1.05E7 -0.92 -1.5832 -0.9839 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H09 compound treatment 7.5408293E7 -1.99E7 -1.72 6.5087699E7 -2.58E7 -2.26 -2.8157 -0.9909 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H10 compound treatment 8.7161748E7 -8160000.0 -0.71 7.9070386E7 -1.19E7 -1.04 -1.2326 -0.9822 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H11 compound treatment 9.3060297E7 -2260000.0 -0.2 8.7980922E7 -2950000.0 -0.26 -0.3209 -0.9906 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H12 compound treatment 8.5630481E7 -9690000.0 -0.84 7.787174E7 -1.31E7 -1.14 -1.4003 -0.9883 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H13 compound treatment 7.0057237E7 -2.53E7 -2.18 6.3253538E7 -2.77E7 -2.42 -3.2561 -0.9986 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H14 compound treatment 7.6955473E7 -1.84E7 -1.59 6.994122E7 -2.1E7 -1.84 -2.4209 -0.9973 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H15 compound treatment 7.2142657E7 -2.32E7 -2.0 6.159739E7 -2.93E7 -2.57 -3.2312 -0.9924 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H16 compound treatment 9.4691025E7 -634000.0 -0.05 8.6614411E7 -4320000.0 -0.38 -0.3059 -0.8012 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H17 compound treatment 9.4702315E7 -623000.0 -0.05 9.0154739E7 -777000.0 -0.07 -0.0861 -0.9933 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H18 compound treatment 9.2109474E7 -3220000.0 -0.28 8.9551692E7 -1380000.0 -0.12 -0.2818 -0.9304 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H19 mock treatment 1.01678944E8 6350000.0 0.55 9.6219115E7 5290000.0 0.46 0.7153 0.9964 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H20 mock treatment 9.8025477E7 2700000.0 0.23 9.2997965E7 2070000.0 0.18 0.2928 0.9921 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H21 compound treatment 7.520263E7 -2.01E7 -1.74 7.2330889E7 -1.86E7 -1.63 -2.3801 -0.9995 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H22 compound treatment 9.1512496E7 -3810000.0 -0.33 8.6123202E7 -4810000.0 -0.42 -0.5304 -0.9926 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H23 compound treatment 8.420293E7 -1.11E7 -0.96 7.2739371E7 -1.82E7 -1.59 -1.8051 -0.9707 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 H24 compound treatment 7.0197556E7 -2.51E7 -2.17 6.6241202E7 -2.47E7 -2.16 -3.0626 -1.0 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I01 compound treatment 1.05834883E8 1.05E7 0.91 9.3187084E7 2260000.0 0.2 0.7815 0.8412 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I02 compound treatment 8.5045017E7 -1.03E7 -0.89 8.147621E7 -9460000.0 -0.83 -1.213 -0.9994 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I03 compound treatment 9.8972453E7 3650000.0 0.32 9.6228055E7 5300000.0 0.46 0.5505 0.9823 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I04 compound treatment 9.7086282E7 1760000.0 0.15 9.3479432E7 2550000.0 0.22 0.2652 0.9826 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I05 mock treatment 9.3943075E7 -1380000.0 -0.12 9.4567188E7 3640000.0 0.32 0.1406 0.4137 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I06 mock treatment 9.1853848E7 -3470000.0 -0.3 8.9987443E7 -944000.0 -0.08 -0.2704 -0.8695 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I07 compound treatment 9.3335398E7 -1990000.0 -0.17 8.9497684E7 -1430000.0 -0.13 -0.2103 -0.988 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I08 compound treatment 8.9711059E7 -5610000.0 -0.48 8.6787949E7 -4140000.0 -0.36 -0.5993 -0.9898 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I09 compound treatment 9.5819279E7 494000.0 0.04 9.2375447E7 1440000.0 0.13 0.1195 0.8962 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I10 compound treatment 8.6980234E7 -8340000.0 -0.72 8.3231976E7 -7700000.0 -0.67 -0.9861 -0.9994 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I11 compound treatment 8.765384E7 -7670000.0 -0.66 8.5748492E7 -5180000.0 -0.45 -0.7893 -0.9829 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I12 compound treatment 8.5238461E7 -1.01E7 -0.87 7.7476513E7 -1.35E7 -1.18 -1.4487 -0.989 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I13 compound treatment 8.9601968E7 -5720000.0 -0.49 8.7022555E7 -3910000.0 -0.34 -0.5914 -0.9838 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I14 compound treatment 8.279096E7 -1.25E7 -1.08 7.8357202E7 -1.26E7 -1.1 -1.5437 -1.0 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I15 compound treatment 8.8382242E7 -6940000.0 -0.6 8.2205505E7 -8730000.0 -0.76 -0.964 -0.9928 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I16 compound treatment 8.9445441E7 -5880000.0 -0.51 8.2045638E7 -8890000.0 -0.78 -0.909 -0.9787 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I17 compound treatment 9.334902E7 -1980000.0 -0.17 8.8854766E7 -2080000.0 -0.18 -0.2492 -0.9995 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I18 compound treatment 9.498305E7 -342000.0 -0.03 9.2007136E7 1080000.0 0.09 0.0457 0.4629 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I19 compound treatment 9.8000952E7 2680000.0 0.23 9.1751149E7 820000.0 0.07 0.2141 0.8849 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I20 compound treatment 8.0811608E7 -1.45E7 -1.25 7.6398148E7 -1.45E7 -1.27 -1.7858 -1.0 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I21 mock treatment 9.8536296E7 3210000.0 0.28 9.6474826E7 5540000.0 0.49 0.5392 0.9648 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I22 mock treatment 9.9835783E7 4510000.0 0.39 9.7327714E7 6400000.0 0.56 0.6713 0.9843 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I23 compound treatment 1.00394196E8 5070000.0 0.44 9.848984E7 7560000.0 0.66 0.7773 0.9799 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 I24 compound treatment 1.04328945E8 9000000.0 0.78 1.02078857E8 1.11E7 0.98 1.2397 0.9937 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J01 compound treatment 7.0021396E7 -2.53E7 -2.19 6.0341962E7 -3.06E7 -2.68 -3.4384 -0.9949 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J02 compound treatment 8.0953506E7 -1.44E7 -1.24 8.0155694E7 -1.08E7 -0.94 -1.5446 -0.9908 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J03 compound treatment 9.0555674E7 -4770000.0 -0.41 8.8734369E7 -2200000.0 -0.19 -0.4273 -0.9398 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J04 compound treatment 8.9810945E7 -5510000.0 -0.48 9.3308581E7 2380000.0 0.21 -0.1897 -0.3649 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J05 mock treatment 9.9522168E7 4200000.0 0.36 9.7917954E7 6990000.0 0.61 0.6887 0.9689 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J06 mock treatment 8.9915779E7 -5410000.0 -0.47 8.8061681E7 -2870000.0 -0.25 -0.508 -0.9576 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J07 compound treatment 7.4623369E7 -2.07E7 -1.79 7.0215813E7 -2.07E7 -1.81 -2.5463 -1.0 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J08 compound treatment 8.6031289E7 -9290000.0 -0.8 8.0553118E7 -1.04E7 -0.91 -1.2099 -0.9981 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J09 compound treatment 8.9520558E7 -5800000.0 -0.5 8.4450362E7 -6480000.0 -0.57 -0.7556 -0.9981 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J10 compound treatment 8.588987E7 -9440000.0 -0.81 8.4915882E7 -6020000.0 -0.53 -0.9485 -0.9776 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J11 compound treatment 6.8633511E7 -2.67E7 -2.31 7.0012333E7 -2.09E7 -1.83 -2.9247 -0.9935 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J12 compound treatment 8.5410128E7 -9920000.0 -0.86 8.7001612E7 -3930000.0 -0.34 -0.8488 -0.9197 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J13 compound treatment 5.9721923E7 -3.56E7 -3.08 5.685349E7 -3.41E7 -2.98 -4.2833 -0.9999 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J14 compound treatment 7.2813542E7 -2.25E7 -1.94 6.4679386E7 -2.63E7 -2.3 -2.9995 -0.9966 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J15 compound treatment 9.1474743E7 -3850000.0 -0.33 8.7559066E7 -3370000.0 -0.3 -0.4439 -0.9982 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J16 compound treatment 8.2289045E7 -1.3E7 -1.13 7.5387047E7 -1.55E7 -1.36 -1.7581 -0.9956 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J17 compound treatment 8.9125011E7 -6200000.0 -0.54 8.4576751E7 -6350000.0 -0.56 -0.7719 -0.9998 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J18 compound treatment 4.1543034E7 -5.38E7 -4.65 3.845217E7 -5.25E7 -4.59 -6.5324 -1.0 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J19 compound treatment 9.7032407E7 1710000.0 0.15 9.4063678E7 3130000.0 0.27 0.2981 0.9577 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J20 compound treatment 9.0210027E7 -5120000.0 -0.44 9.2051096E7 1120000.0 0.1 -0.2431 -0.5372 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J21 mock treatment 9.9847927E7 4520000.0 0.39 9.7851605E7 6920000.0 0.61 0.7045 0.9775 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J22 mock treatment 9.6718407E7 1390000.0 0.12 9.4819066E7 3890000.0 0.34 0.3257 0.9024 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J23 compound treatment 1.04352184E8 9030000.0 0.78 9.7129406E7 6200000.0 0.54 0.9349 0.9843 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 J24 compound treatment 8.3293598E7 -1.2E7 -1.04 8.30206E7 -7910000.0 -0.69 -1.2244 -0.9805 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K01 compound treatment 1.01379978E8 6050000.0 0.52 9.9567389E7 8640000.0 0.76 0.9042 0.9838 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K02 compound treatment 8.6285499E7 -9040000.0 -0.78 8.5863407E7 -5070000.0 -0.44 -0.8657 -0.9641 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K03 compound treatment 8.8418291E7 -6910000.0 -0.6 9.2905501E7 1970000.0 0.17 -0.2997 -0.4825 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K04 compound treatment 9.4068619E7 -1260000.0 -0.11 9.3027552E7 2100000.0 0.18 0.053 0.2485 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K05 compound treatment 8.225488E7 -1.31E7 -1.13 7.4889278E7 -1.6E7 -1.4 -1.791 -0.9942 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K06 compound treatment 8.3064124E7 -1.23E7 -1.06 7.3665021E7 -1.73E7 -1.51 -1.8174 -0.9849 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K07 mock treatment 9.1510258E7 -3810000.0 -0.33 9.165028E7 719000.0 0.06 -0.1885 -0.5619 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K08 mock treatment 8.9144258E7 -6180000.0 -0.53 8.6611456E7 -4320000.0 -0.38 -0.6448 -0.9857 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K09 compound treatment 7.7621016E7 -1.77E7 -1.53 8.7013216E7 -3920000.0 -0.34 -1.3237 -0.8447 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K10 compound treatment 8.4582488E7 -1.07E7 -0.93 7.7000455E7 -1.39E7 -1.22 -1.5182 -0.9909 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K11 compound treatment 6.7216426E7 -2.81E7 -2.43 6.8164102E7 -2.28E7 -1.99 -3.1257 -0.9952 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K12 compound treatment 6.9135263E7 -2.62E7 -2.26 7.1271828E7 -1.97E7 -1.72 -2.8162 -0.9909 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K13 compound treatment 9.1883121E7 -3440000.0 -0.3 8.8047213E7 -2880000.0 -0.25 -0.3887 -0.9967 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K14 compound treatment 9.1724804E7 -3600000.0 -0.31 8.1333701E7 -9600000.0 -0.84 -0.8138 -0.9086 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K15 mock treatment 9.6757619E7 1430000.0 0.12 9.3177591E7 2250000.0 0.2 0.2265 0.9751 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K16 mock treatment 9.1036266E7 -4290000.0 -0.37 8.3834272E7 -7100000.0 -0.62 -0.7011 -0.9695 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K17 compound treatment 1.02117567E8 6790000.0 0.59 9.3058695E7 2130000.0 0.19 0.5465 0.8879 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K18 compound treatment 9.9056559E7 3730000.0 0.32 9.1848179E7 917000.0 0.08 0.2846 0.857 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K19 compound treatment 6.5316465E7 -3.0E7 -2.59 5.5507985E7 -3.54E7 -3.1 -4.0249 -0.996 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K20 compound treatment 8.8555946E7 -6770000.0 -0.58 8.5670075E7 -5260000.0 -0.46 -0.739 -0.993 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K21 compound treatment 9.7719649E7 2390000.0 0.21 1.01684415E8 1.08E7 0.94 0.8117 0.8424 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K22 compound treatment 8.1389211E7 -1.39E7 -1.2 8.0376142E7 -1.06E7 -0.92 -1.5043 -0.9915 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K23 mock treatment 1.05357459E8 1.0E7 0.87 1.00218266E8 9290000.0 0.81 1.1874 0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 K24 mock treatment 9.7120638E7 1800000.0 0.16 9.7843196E7 6910000.0 0.6 0.5374 0.8606 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L01 compound treatment 7.8451478E7 -1.69E7 -1.46 7.5828321E7 -1.51E7 -1.32 -1.9652 -0.9988 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L02 compound treatment 9.6504577E7 1180000.0 0.1 8.8187119E7 -2740000.0 -0.24 -0.0978 -0.3749 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L03 compound treatment 7.9423945E7 -1.59E7 -1.37 7.8580325E7 -1.24E7 -1.08 -1.7355 -0.993 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L04 compound treatment 9.0238593E7 -5090000.0 -0.44 8.997105E7 -960000.0 -0.08 -0.3701 -0.8274 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L05 compound treatment 7.8145723E7 -1.72E7 -1.48 7.3838163E7 -1.71E7 -1.5 -2.107 -1.0 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L06 compound treatment 8.6378623E7 -8950000.0 -0.77 8.434574E7 -6590000.0 -0.58 -0.954 -0.9896 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L07 mock treatment 9.0670009E7 -4660000.0 -0.4 8.9631819E7 -1300000.0 -0.11 -0.3647 -0.8729 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L08 mock treatment 8.8614323E7 -6710000.0 -0.58 8.7331525E7 -3600000.0 -0.32 -0.6326 -0.9589 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L09 compound treatment 7.3874848E7 -2.15E7 -1.85 7.1557979E7 -1.94E7 -1.7 -2.509 -0.999 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L10 compound treatment 7.6461464E7 -1.89E7 -1.63 8.6430407E7 -4500000.0 -0.39 -1.4306 -0.8535 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L11 compound treatment 6.7486702E7 -2.78E7 -2.4 6.5433418E7 -2.55E7 -2.23 -3.2781 -0.9993 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L12 compound treatment 6.357751E7 -3.17E7 -2.74 8.493189E7 -6000000.0 -0.53 -2.3103 -0.8275 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L13 compound treatment 7.5721537E7 -1.96E7 -1.69 6.9086348E7 -2.18E7 -1.91 -2.5491 -0.9982 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L14 compound treatment 6.7556791E7 -2.78E7 -2.4 6.1940484E7 -2.9E7 -2.54 -3.49 -0.9996 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L15 mock treatment 9.4504253E7 -821000.0 -0.07 9.3177237E7 2250000.0 0.2 0.0888 0.4252 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L16 mock treatment 9.245742E7 -2870000.0 -0.25 9.2762177E7 1830000.0 0.16 -0.0619 -0.2097 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L17 compound treatment 8.7049285E7 -8280000.0 -0.71 8.150541E7 -9430000.0 -0.82 -1.0888 -0.9975 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L18 compound treatment 6.8385228E7 -2.69E7 -2.33 6.0575812E7 -3.04E7 -2.66 -3.5239 -0.9978 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L19 compound treatment 8.8858665E7 -6470000.0 -0.56 8.5178791E7 -5750000.0 -0.5 -0.7509 -0.9987 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L20 compound treatment 9.7880721E7 2560000.0 0.22 9.8058916E7 7130000.0 0.62 0.5972 0.9025 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L21 compound treatment 9.6075577E7 750000.0 0.06 9.1005478E7 74000.0 0.01 0.0504 0.774 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L22 compound treatment 9.170369E7 -3620000.0 -0.31 8.6737159E7 -4190000.0 -0.37 -0.4807 -0.9968 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L23 mock treatment 1.05955433E8 1.06E7 0.92 1.07375526E8 1.64E7 1.44 1.6669 0.9764 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 L24 mock treatment 1.04442929E8 9120000.0 0.79 1.0166684E8 1.07E7 0.94 1.2212 0.9961 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M01 compound treatment 8.7102125E7 -8220000.0 -0.71 8.0665643E7 -1.03E7 -0.9 -1.1375 -0.9932 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M02 compound treatment 9.4378305E7 -947000.0 -0.08 8.0471413E7 -1.05E7 -0.92 -0.7051 -0.7672 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M03 compound treatment 9.3967121E7 -1360000.0 -0.12 1.01176821E8 1.02E7 0.9 0.5511 0.6094 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M04 compound treatment 9.0867626E7 -4460000.0 -0.39 8.0883819E7 -1.0E7 -0.88 -0.894 -0.9313 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M05 compound treatment 9.7881718E7 2560000.0 0.22 1.00098179E8 9170000.0 0.8 0.7234 0.8694 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M06 compound treatment 8.5903806E7 -9420000.0 -0.81 9.0815267E7 -116000.0 -0.01 -0.5826 -0.7159 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M07 compound treatment 9.6661865E7 1340000.0 0.12 7.3979729E7 -1.7E7 -1.48 -0.9674 -0.6501 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M08 compound treatment 7.8975592E7 -1.63E7 -1.41 7.5132028E7 -1.58E7 -1.38 -1.9763 -0.9999 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M09 mock treatment 8.8468961E7 -6860000.0 -0.59 9.125239E7 321000.0 0.03 -0.3989 -0.6728 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M10 mock treatment 8.8338404E7 -6990000.0 -0.6 8.6886498E7 -4040000.0 -0.35 -0.677 -0.9677 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M11 compound treatment 6.7910792E7 -2.74E7 -2.37 7.599331E7 -1.49E7 -1.31 -2.5988 -0.9608 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M12 compound treatment 5.3391686E7 -4.19E7 -3.62 6.165315E7 -2.93E7 -2.56 -4.3729 -0.9856 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M13 mock treatment 8.8832967E7 -6490000.0 -0.56 8.6306236E7 -4630000.0 -0.4 -0.6827 -0.9872 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M14 mock treatment 8.761733E7 -7710000.0 -0.67 7.8843515E7 -1.21E7 -1.06 -1.2188 -0.9751 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M15 compound treatment 8.2759043E7 -1.26E7 -1.09 8.5594362E7 -5340000.0 -0.47 -1.0978 -0.929 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M16 compound treatment 9.0224137E7 -5100000.0 -0.44 8.7200143E7 -3730000.0 -0.33 -0.5425 -0.9891 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M17 compound treatment 9.2884771E7 -2440000.0 -0.21 7.8694774E7 -1.22E7 -1.07 -0.9063 -0.8304 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M18 compound treatment 8.7779499E7 -7550000.0 -0.65 8.8061174E7 -2870000.0 -0.25 -0.6385 -0.9141 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M19 compound treatment 1.02319143E8 6990000.0 0.6 9.3958286E7 3030000.0 0.26 0.6145 0.9316 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M20 compound treatment 9.9917488E7 4590000.0 0.4 9.4082844E7 3150000.0 0.28 0.4755 0.9842 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M21 compound treatment 7.7702197E7 -1.76E7 -1.52 1.02212164E8 1.13E7 0.99 -0.3782 -0.2085 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M22 compound treatment 9.9223778E7 3900000.0 0.34 8.6624737E7 -4310000.0 -0.38 -0.0284 -0.0562 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M23 compound treatment 2.1164009E7 -7.42E7 -6.41 2.100289E7 -6.99E7 -6.12 -8.8568 -0.9997 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 M24 compound treatment 8.4803168E7 -1.05E7 -0.91 8.0475775E7 -1.05E7 -0.92 -1.2897 -1.0 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N01 compound treatment 7.928134E7 -1.6E7 -1.39 7.530392E7 -1.56E7 -1.37 -1.947 -1.0 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N02 compound treatment 8.3085338E7 -1.22E7 -1.06 8.3858224E7 -7070000.0 -0.62 -1.1853 -0.9675 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N03 compound treatment 7.1530253E7 -2.38E7 -2.06 6.4561847E7 -2.64E7 -2.31 -3.0851 -0.9983 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N04 compound treatment 9.4916716E7 -408000.0 -0.04 9.6820544E7 5890000.0 0.52 0.3395 0.6572 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N05 compound treatment 7.8990742E7 -1.63E7 -1.41 7.9204811E7 -1.17E7 -1.03 -1.7233 -0.9878 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N06 compound treatment 9.4285774E7 -1040000.0 -0.09 8.9319915E7 -1610000.0 -0.14 -0.1632 -0.9762 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N07 compound treatment 8.5491237E7 -9830000.0 -0.85 7.6734327E7 -1.42E7 -1.24 -1.4792 -0.9828 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N08 compound treatment 6.7340748E7 -2.8E7 -2.42 6.0164912E7 -3.08E7 -2.69 -3.6131 -0.9985 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N09 mock treatment 9.6730273E7 1410000.0 0.12 9.0474205E7 -457000.0 -0.04 0.0575 0.4501 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N10 mock treatment 8.8614575E7 -6710000.0 -0.58 8.7626449E7 -3300000.0 -0.29 -0.6144 -0.9484 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N11 compound treatment 4.7446946E7 -4.79E7 -4.14 5.5496907E7 -3.54E7 -3.1 -5.117 -0.9899 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N12 compound treatment 5.0047137E7 -4.53E7 -3.91 7.9082387E7 -1.18E7 -1.04 -3.4986 -0.8647 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N13 mock treatment 9.379914E7 -1530000.0 -0.13 9.0606697E7 -325000.0 -0.03 -0.1133 -0.8403 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N14 mock treatment 9.1976477E7 -3350000.0 -0.29 8.5771895E7 -5160000.0 -0.45 -0.5238 -0.9768 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N15 compound treatment 6.8003503E7 -2.73E7 -2.36 6.429565E7 -2.66E7 -2.33 -3.317 -1.0 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N16 compound treatment 9.3782445E7 -1540000.0 -0.13 8.6857187E7 -4070000.0 -0.36 -0.3464 -0.9099 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N17 compound treatment 5.8816169E7 -3.65E7 -3.15 5.3014605E7 -3.79E7 -3.32 -4.5762 -0.9997 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N18 compound treatment 7.5082608E7 -2.02E7 -1.75 7.1844782E7 -1.91E7 -1.67 -2.4175 -0.9997 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N19 compound treatment 2.6567259E7 -6.88E7 -5.94 2.7499495E7 -6.34E7 -5.55 -8.1248 -0.9994 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N20 compound treatment 9.1506582E7 -3820000.0 -0.33 8.8853641E7 -2080000.0 -0.18 -0.3618 -0.9606 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N21 compound treatment 8.0710204E7 -1.46E7 -1.26 6.9585747E7 -2.13E7 -1.87 -2.2136 -0.9818 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N22 compound treatment 9.8989707E7 3660000.0 0.32 9.694499E7 6010000.0 0.53 0.596 0.9704 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N23 compound treatment 7.5393172E7 -1.99E7 -1.72 6.8545627E7 -2.24E7 -1.96 -2.6027 -0.9979 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 N24 compound treatment 9.6163199E7 838000.0 0.07 9.114673E7 215000.0 0.02 0.0645 0.8624 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O01 compound treatment 8.1234925E7 -1.41E7 -1.22 7.7036764E7 -1.39E7 -1.22 -1.7204 -1.0 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O02 compound treatment 9.8046291E7 2720000.0 0.24 7.8574938E7 -1.24E7 -1.08 -0.5985 -0.5408 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O03 compound treatment 4.0841007E7 -5.45E7 -4.71 2.1611844E7 -6.93E7 -6.07 -7.6174 -0.9921 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O04 compound treatment 8.1108024E7 -1.42E7 -1.23 8.4621447E7 -6310000.0 -0.55 -1.2588 -0.9349 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O05 compound treatment 1.00874953E8 5550000.0 0.48 9.7625662E7 6690000.0 0.59 0.7532 0.995 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O06 compound treatment 9.7443767E7 2120000.0 0.18 9.1125733E7 194000.0 0.02 0.1414 0.7695 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O07 compound treatment 9.8253759E7 2930000.0 0.25 9.5207413E7 4280000.0 0.37 0.4435 0.9818 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O08 compound treatment 8.0102467E7 -1.52E7 -1.31 7.7995444E7 -1.29E7 -1.13 -1.7303 -0.9972 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O09 compound treatment 3.2077442E7 -6.32E7 -5.46 2.073078E7 -7.02E7 -6.14 -8.2071 -0.9983 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O10 compound treatment 7.7534025E7 -1.78E7 -1.54 7.2680434E7 -1.83E7 -1.6 -2.216 -0.9998 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O11 mock treatment 9.3816355E7 -1510000.0 -0.13 8.6527147E7 -4400000.0 -0.39 -0.3647 -0.8963 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O12 mock treatment 8.6605204E7 -8720000.0 -0.75 8.4221982E7 -6710000.0 -0.59 -0.9478 -0.9924 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O13 compound treatment 8.6273361E7 -9050000.0 -0.78 7.6064273E7 -1.49E7 -1.3 -1.4729 -0.9703 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O14 compound treatment 8.7188147E7 -8140000.0 -0.7 7.8354667E7 -1.26E7 -1.1 -1.2753 -0.9765 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O15 compound treatment 9.5493428E7 168000.0 0.01 8.8357453E7 -2570000.0 -0.23 -0.149 -0.6601 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O16 compound treatment 8.7307501E7 -8020000.0 -0.69 8.284308E7 -8090000.0 -0.71 -0.9902 -0.9999 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O17 compound treatment 7.6623897E7 -1.87E7 -1.62 6.7690582E7 -2.32E7 -2.03 -2.5804 -0.9935 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O18 compound treatment 9.7561587E7 2240000.0 0.19 9.348263E7 2550000.0 0.22 0.2945 0.9974 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O19 compound treatment 6.8612193E7 -2.67E7 -2.31 6.298212E7 -2.79E7 -2.45 -3.3611 -0.9996 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O20 compound treatment 9.8792377E7 3470000.0 0.3 8.9395655E7 -1540000.0 -0.13 0.1167 0.3556 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O21 compound treatment 2.2799739E7 -7.25E7 -6.26 2.6574493E7 -6.44E7 -5.63 -8.4121 -0.9986 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O22 compound treatment 1.00669016E8 5340000.0 0.46 9.7991537E7 7060000.0 0.62 0.7633 0.9897 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O23 compound treatment 1.01129304E8 5800000.0 0.5 9.9041977E7 8110000.0 0.71 0.8564 0.9855 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 O24 compound treatment 9.4286882E7 -1040000.0 -0.09 9.0016268E7 -915000.0 -0.08 -0.12 -0.9984 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P01 compound treatment 8.0198202E7 -1.51E7 -1.31 6.801438E7 -2.29E7 -2.01 -2.3421 -0.9784 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P02 compound treatment 7.0726789E7 -2.46E7 -2.12 6.0169275E7 -3.08E7 -2.69 -3.406 -0.9931 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P03 compound treatment 7.3817397E7 -2.15E7 -1.86 6.2219959E7 -2.87E7 -2.51 -3.0904 -0.989 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P04 compound treatment 7.6581587E7 -1.87E7 -1.62 6.6550009E7 -2.44E7 -2.13 -2.6536 -0.9907 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P05 compound treatment 7.1817567E7 -2.35E7 -2.03 5.1391775E7 -3.95E7 -3.46 -3.8826 -0.9677 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P06 compound treatment 8.2269056E7 -1.31E7 -1.13 7.4300525E7 -1.66E7 -1.46 -1.8266 -0.992 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P07 compound treatment 8.7965434E7 -7360000.0 -0.64 8.2197562E7 -8730000.0 -0.76 -0.99 -0.9958 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P08 compound treatment 9.4318953E7 -1010000.0 -0.09 8.3982523E7 -6950000.0 -0.61 -0.4915 -0.8 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P09 compound treatment 7.4949045E7 -2.04E7 -1.76 6.7742015E7 -2.32E7 -2.03 -2.6795 -0.9975 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P10 compound treatment 9.4259525E7 -1070000.0 -0.09 8.8698431E7 -2230000.0 -0.2 -0.2033 -0.941 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P11 mock treatment 9.4880636E7 -445000.0 -0.04 8.3015948E7 -7920000.0 -0.69 -0.517 -0.7452 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P12 mock treatment 9.2046641E7 -3280000.0 -0.28 8.5119323E7 -5810000.0 -0.51 -0.5599 -0.9618 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P13 compound treatment 7.4651635E7 -2.07E7 -1.79 6.1103935E7 -2.98E7 -2.61 -3.1085 -0.9829 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P14 compound treatment 8.4659722E7 -1.07E7 -0.92 7.9249147E7 -1.17E7 -1.02 -1.3743 -0.9986 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P15 compound treatment 8.2525285E7 -1.28E7 -1.11 8.1554445E7 -9380000.0 -0.82 -1.362 -0.9892 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P16 compound treatment 9.6989943E7 1660000.0 0.14 8.7336007E7 -3600000.0 -0.31 -0.1208 -0.3493 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P17 compound treatment 8.790289E7 -7420000.0 -0.64 8.1168923E7 -9760000.0 -0.85 -1.0575 -0.99 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P18 compound treatment 9.9855322E7 4530000.0 0.39 9.0364623E7 -567000.0 -0.05 0.2416 0.6126 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P19 compound treatment 8.0001089E7 -1.53E7 -1.32 6.9795091E7 -2.11E7 -1.85 -2.2439 -0.9865 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P20 compound treatment 9.6854619E7 1530000.0 0.13 8.9718158E7 -1210000.0 -0.11 0.0183 0.1081 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P21 compound treatment 5.6819747E7 -3.85E7 -3.33 5.101902E7 -3.99E7 -3.49 -4.8216 -0.9997 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P22 compound treatment 9.7432838E7 2110000.0 0.18 9.5703279E7 4770000.0 0.42 0.424 0.9308 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P23 compound treatment 9.8305712E7 2980000.0 0.26 8.5569613E7 -5360000.0 -0.47 -0.1498 -0.2798 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2093 P24 compound treatment 8.4845711E7 -1.05E7 -0.91 7.7175294E7 -1.38E7 -1.2 -1.4913 -0.9901 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A01 compound treatment 1.01719495E8 7840000.0 0.68 9.8618784E7 5770000.0 0.5 0.8362 0.9895 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A02 compound treatment 7.191089E7 -2.2E7 -1.9 7.2275731E7 -2.06E7 -1.8 -2.6146 -0.9997 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A03 compound treatment 8.5054393E7 -8820000.0 -0.76 8.1939525E7 -1.09E7 -0.95 -1.2138 -0.9937 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A04 compound treatment 9.133588E7 -2540000.0 -0.22 8.9401437E7 -3450000.0 -0.3 -0.3684 -0.9877 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A05 compound treatment 1.01882551E8 8010000.0 0.69 9.8474523E7 5630000.0 0.49 0.8372 0.9861 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A06 compound treatment 9.5018043E7 1140000.0 0.1 8.3076195E7 -9770000.0 -0.86 -0.535 -0.6214 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A07 compound treatment 9.2489031E7 -1390000.0 -0.12 8.696833E7 -5880000.0 -0.51 -0.4486 -0.8489 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A08 compound treatment 8.1989795E7 -1.19E7 -1.03 7.9608917E7 -1.32E7 -1.16 -1.5452 -0.9982 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A09 compound treatment 8.9541753E7 -4330000.0 -0.37 8.9995423E7 -2850000.0 -0.25 -0.4412 -0.9806 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A10 compound treatment 9.0767723E7 -3110000.0 -0.27 8.9941372E7 -2910000.0 -0.25 -0.3697 -0.9996 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A11 compound treatment 7.9893088E7 -1.4E7 -1.21 7.143818E7 -2.14E7 -1.87 -2.1789 -0.9774 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A12 compound treatment 7.4315043E7 -1.96E7 -1.69 7.1932945E7 -2.09E7 -1.83 -2.489 -0.9992 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A13 mock treatment 9.0476231E7 -3400000.0 -0.29 9.3618919E7 770000.0 0.07 -0.1599 -0.531 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A14 mock treatment 1.00136313E8 6260000.0 0.54 9.3436742E7 588000.0 0.05 0.4188 0.7709 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A15 compound treatment 8.838845E7 -5490000.0 -0.47 7.9051196E7 -1.38E7 -1.21 -1.189 -0.9166 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A16 compound treatment 8.5440763E7 -8430000.0 -0.73 7.8963113E7 -1.39E7 -1.22 -1.3744 -0.9701 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A17 compound treatment 8.8519216E7 -5360000.0 -0.46 9.4990864E7 2140000.0 0.19 -0.1946 -0.3898 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A18 compound treatment 7.4017391E7 -1.99E7 -1.72 6.4930083E7 -2.79E7 -2.44 -2.9405 -0.985 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A19 compound treatment 5.6070198E7 -3.78E7 -3.27 5.2130646E7 -4.07E7 -3.56 -4.8287 -0.999 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A20 compound treatment 8.6510355E7 -7360000.0 -0.64 8.5544091E7 -7300000.0 -0.64 -0.9019 -1.0 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A21 compound treatment 9.2210143E7 -1670000.0 -0.14 9.6585352E7 3740000.0 0.33 0.1295 0.3626 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A22 compound treatment 1.03845976E8 9970000.0 0.86 9.9877736E7 7030000.0 0.62 1.0439 0.9864 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A23 compound treatment 1.05350092E8 1.15E7 0.99 9.3243531E7 395000.0 0.03 0.7252 0.7313 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 A24 compound treatment 1.03378306E8 9500000.0 0.82 1.0303767E8 1.02E7 0.89 1.2109 0.9991 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B01 compound treatment 9.5120376E7 1250000.0 0.11 8.7125296E7 -5720000.0 -0.5 -0.2782 -0.5429 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B02 compound treatment 7.2688291E7 -2.12E7 -1.83 6.8912026E7 -2.39E7 -2.09 -2.7753 -0.9977 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B03 compound treatment 8.4281176E7 -9590000.0 -0.83 8.1079942E7 -1.18E7 -1.03 -1.3143 -0.9942 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B04 compound treatment 4.8781622E7 -4.51E7 -3.89 4.7167177E7 -4.57E7 -4.0 -5.581 -0.9999 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B05 compound treatment 8.7239834E7 -6640000.0 -0.57 8.2730569E7 -1.01E7 -0.89 -1.0314 -0.9778 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B06 compound treatment 5.5979448E7 -3.79E7 -3.27 5.3434375E7 -3.94E7 -3.45 -4.7536 -0.9997 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B07 compound treatment 7.335987E7 -2.05E7 -1.77 7.1646309E7 -2.12E7 -1.86 -2.5651 -0.9997 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B08 compound treatment 6.9970452E7 -2.39E7 -2.06 7.0219531E7 -2.26E7 -1.98 -2.8604 -0.9998 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B09 compound treatment 8.2032018E7 -1.18E7 -1.02 7.9703048E7 -1.31E7 -1.15 -1.5368 -0.9983 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B10 compound treatment 7.3155129E7 -2.07E7 -1.79 6.3661161E7 -2.92E7 -2.55 -3.0717 -0.9849 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B11 compound treatment 6.6711425E7 -2.72E7 -2.35 6.4774401E7 -2.81E7 -2.46 -3.3964 -0.9997 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B12 compound treatment 4.3551546E7 -5.03E7 -4.35 3.8018513E7 -5.48E7 -4.8 -6.4666 -0.9988 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B13 mock treatment 9.5326624E7 1450000.0 0.13 9.1595287E7 -1250000.0 -0.11 0.0111 0.0664 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B14 mock treatment 9.2728087E7 -1150000.0 -0.1 8.2202943E7 -1.06E7 -0.93 -0.7289 -0.7779 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B15 compound treatment 9.4360177E7 485000.0 0.04 8.3313327E7 -9540000.0 -0.83 -0.5605 -0.6708 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B16 compound treatment 6.0928854E7 -3.29E7 -2.85 6.4178451E7 -2.87E7 -2.51 -3.7864 -0.998 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B17 compound treatment 8.8476066E7 -5400000.0 -0.47 8.7917137E7 -4930000.0 -0.43 -0.6349 -0.9993 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B18 compound treatment 6.8326766E7 -2.55E7 -2.21 6.7370698E7 -2.55E7 -2.23 -3.1371 -1.0 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B19 compound treatment 6.7625307E7 -2.63E7 -2.27 5.9234528E7 -3.36E7 -2.94 -3.6834 -0.9917 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B20 compound treatment 6.6189994E7 -2.77E7 -2.39 7.0517713E7 -2.23E7 -1.95 -3.0728 -0.995 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B21 compound treatment 7.2595804E7 -2.13E7 -1.84 6.4165534E7 -2.87E7 -2.51 -3.0747 -0.9883 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B22 compound treatment 7.813144E7 -1.57E7 -1.36 7.0180813E7 -2.27E7 -1.98 -2.3643 -0.983 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B23 compound treatment 6.6203477E7 -2.77E7 -2.39 5.9633153E7 -3.32E7 -2.91 -3.7456 -0.9953 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 B24 compound treatment 8.4918264E7 -8960000.0 -0.77 9.1155003E7 -1690000.0 -0.15 -0.6519 -0.8275 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C01 compound treatment 1.03861326E8 9990000.0 0.86 9.8477855E7 5630000.0 0.49 0.9582 0.9647 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C02 compound treatment 8.8132156E7 -5740000.0 -0.5 8.031285E7 -1.25E7 -1.1 -1.1265 -0.9356 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C03 compound treatment 9.1379351E7 -2500000.0 -0.22 9.4045327E7 1200000.0 0.1 -0.0784 -0.3271 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C04 compound treatment 9.9587776E7 5710000.0 0.49 9.648871E7 3640000.0 0.32 0.5741 0.9776 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C05 compound treatment 9.1469073E7 -2410000.0 -0.21 8.4221683E7 -8630000.0 -0.76 -0.6808 -0.8694 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C06 compound treatment 9.2177396E7 -1700000.0 -0.15 8.2108003E7 -1.07E7 -0.94 -0.7684 -0.8077 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C07 compound treatment 8.8985895E7 -4890000.0 -0.42 9.1821052E7 -1030000.0 -0.09 -0.3622 -0.8389 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C08 compound treatment 9.5455404E7 1580000.0 0.14 8.930446E7 -3540000.0 -0.31 -0.1228 -0.3625 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C09 compound treatment 9.2194169E7 -1680000.0 -0.15 8.9590147E7 -3260000.0 -0.29 -0.3043 -0.951 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C10 compound treatment 7.8536051E7 -1.53E7 -1.32 7.3675552E7 -1.92E7 -1.68 -2.1234 -0.9932 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C11 mock treatment 9.3468462E7 -407000.0 -0.04 8.3278228E7 -9570000.0 -0.84 -0.6171 -0.7361 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C12 mock treatment 8.3860695E7 -1.0E7 -0.86 8.8627353E7 -4220000.0 -0.37 -0.8729 -0.928 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C13 compound treatment 9.3260669E7 -615000.0 -0.05 9.1497865E7 -1350000.0 -0.12 -0.1211 -0.9347 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C14 compound treatment 8.9259451E7 -4620000.0 -0.4 8.3338026E7 -9510000.0 -0.83 -0.8705 -0.9432 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C15 mock treatment 9.5148169E7 1270000.0 0.11 8.6861605E7 -5990000.0 -0.52 -0.2928 -0.5468 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C16 mock treatment 8.7733785E7 -6140000.0 -0.53 9.4415328E7 1570000.0 0.14 -0.2781 -0.5077 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C17 compound treatment 9.607058E7 2200000.0 0.19 9.0498838E7 -2350000.0 -0.21 -0.0113 -0.0406 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C18 compound treatment 9.7057096E7 3180000.0 0.27 8.9231383E7 -3620000.0 -0.32 -0.0295 -0.0704 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C19 compound treatment 9.8719077E7 4840000.0 0.42 8.713291E7 -5720000.0 -0.5 -0.0579 -0.0888 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C20 compound treatment 7.8020215E7 -1.59E7 -1.37 8.0861772E7 -1.2E7 -1.05 -1.7101 -0.9913 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C21 compound treatment 1.00812425E8 6940000.0 0.6 9.7220529E7 4370000.0 0.38 0.6942 0.9765 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C22 compound treatment 1.03768824E8 9890000.0 0.85 9.8472398E7 5620000.0 0.49 0.9523 0.9657 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C23 compound treatment 1.06646432E8 1.28E7 1.1 9.2780527E7 -68200.0 -0.01 0.7758 0.7033 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 C24 compound treatment 9.8941286E7 5070000.0 0.44 1.05080198E8 1.22E7 1.07 1.0663 0.9221 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D01 compound treatment 7.750668E7 -1.64E7 -1.41 7.9548458E7 -1.33E7 -1.16 -1.8228 -0.9953 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D02 compound treatment 9.1738466E7 -2140000.0 -0.18 8.6601656E7 -6250000.0 -0.55 -0.5171 -0.8961 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D03 compound treatment 8.3247186E7 -1.06E7 -0.92 7.3272213E7 -1.96E7 -1.71 -1.8606 -0.9572 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D04 compound treatment 8.2503059E7 -1.14E7 -0.98 7.9357669E7 -1.35E7 -1.18 -1.5294 -0.9958 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D05 compound treatment 7.9445049E7 -1.44E7 -1.25 8.0315351E7 -1.25E7 -1.1 -1.6569 -0.998 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D06 compound treatment 8.6281132E7 -7590000.0 -0.66 8.6708688E7 -6140000.0 -0.54 -0.8438 -0.9951 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D07 compound treatment 7.9324694E7 -1.46E7 -1.26 7.3553491E7 -1.93E7 -1.69 -2.0827 -0.9894 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D08 compound treatment 8.8253532E7 -5620000.0 -0.49 8.4686307E7 -8160000.0 -0.71 -0.8485 -0.9823 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D09 compound treatment 8.5888345E7 -7990000.0 -0.69 8.2383169E7 -1.05E7 -0.92 -1.1355 -0.9902 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D10 compound treatment 6.8958597E7 -2.49E7 -2.15 6.7943389E7 -2.49E7 -2.18 -3.063 -1.0 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D11 mock treatment 9.7140367E7 3270000.0 0.28 8.507748E7 -7770000.0 -0.68 -0.2815 -0.3823 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D12 mock treatment 9.1487798E7 -2390000.0 -0.21 8.9399862E7 -3450000.0 -0.3 -0.3592 -0.9827 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D13 compound treatment 7.8055474E7 -1.58E7 -1.37 7.9511389E7 -1.33E7 -1.17 -1.7916 -0.9969 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D14 compound treatment 8.5621817E7 -8250000.0 -0.71 8.3850605E7 -9000000.0 -0.79 -1.0609 -0.9988 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D15 mock treatment 9.9489992E7 5610000.0 0.48 8.6961707E7 -5890000.0 -0.52 -0.0214 -0.0302 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D16 mock treatment 9.6174159E7 2300000.0 0.2 9.3099566E7 251000.0 0.02 0.1559 0.7805 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D17 compound treatment 7.8986319E7 -1.49E7 -1.29 7.3438625E7 -1.94E7 -1.7 -2.1105 -0.9906 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D18 compound treatment 9.148315E7 -2390000.0 -0.21 8.2307838E7 -1.05E7 -0.92 -0.7984 -0.8446 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D19 compound treatment 8.5280052E7 -8600000.0 -0.74 7.5341471E7 -1.75E7 -1.53 -1.6084 -0.9447 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D20 compound treatment 9.2483564E7 -1390000.0 -0.12 8.9982743E7 -2870000.0 -0.25 -0.2624 -0.9433 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D21 compound treatment 7.7406565E7 -1.65E7 -1.42 6.73651E7 -2.55E7 -2.23 -2.5829 -0.9764 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D22 compound treatment 9.8188948E7 4310000.0 0.37 8.9378308E7 -3470000.0 -0.3 0.0487 0.1013 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D23 compound treatment 9.6498212E7 2620000.0 0.23 8.9754045E7 -3090000.0 -0.27 -0.0313 -0.0887 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 D24 compound treatment 4.2018569E7 -5.19E7 -4.48 3.8599176E7 -5.42E7 -4.75 -6.5243 -0.9996 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E01 mock treatment 1.09517478E8 1.56E7 1.35 1.03377108E8 1.05E7 0.92 1.6069 0.9826 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E02 mock treatment 9.7964136E7 4090000.0 0.35 9.8212498E7 5360000.0 0.47 0.5817 0.9902 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E03 compound treatment 8.8619547E7 -5260000.0 -0.45 8.9048259E7 -3800000.0 -0.33 -0.5562 -0.9883 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E04 compound treatment 8.8573159E7 -5300000.0 -0.46 8.3867692E7 -8980000.0 -0.79 -0.8796 -0.9669 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E05 compound treatment 9.3512902E7 -362000.0 -0.03 9.6410043E7 3560000.0 0.31 0.1983 0.6329 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E06 compound treatment 8.5716401E7 -8160000.0 -0.7 8.1509446E7 -1.13E7 -0.99 -1.2 -0.9859 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E07 compound treatment 7.4880857E7 -1.9E7 -1.64 7.3167318E7 -1.97E7 -1.72 -2.378 -0.9997 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E08 compound treatment 8.4417179E7 -9460000.0 -0.82 8.5143355E7 -7710000.0 -0.67 -1.0545 -0.9955 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E09 mock treatment 9.0603631E7 -3270000.0 -0.28 8.7716507E7 -5130000.0 -0.45 -0.5174 -0.9751 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E10 mock treatment 8.7304084E7 -6570000.0 -0.57 8.5948724E7 -6900000.0 -0.6 -0.8283 -0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E11 compound treatment 7.5486266E7 -1.84E7 -1.59 7.3622358E7 -1.92E7 -1.68 -2.3129 -0.9996 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E12 compound treatment 8.9305752E7 -4570000.0 -0.39 8.48854E7 -7960000.0 -0.7 -0.7719 -0.9637 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E13 compound treatment 8.8888808E7 -4990000.0 -0.43 8.7758756E7 -5090000.0 -0.45 -0.6195 -0.9999 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E14 compound treatment 8.4900584E7 -8970000.0 -0.78 8.5186793E7 -7660000.0 -0.67 -1.0223 -0.9974 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E15 compound treatment 9.7448703E7 3570000.0 0.31 9.3757036E7 908000.0 0.08 0.2745 0.8611 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E16 compound treatment 8.1719349E7 -1.22E7 -1.05 8.2894081E7 -9950000.0 -0.87 -1.3585 -0.9957 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E17 mock treatment 9.8719044E7 4840000.0 0.42 9.8518548E7 5670000.0 0.5 0.6467 0.9964 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E18 mock treatment 1.01212971E8 7340000.0 0.63 9.9472143E7 6620000.0 0.58 0.858 0.999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E19 compound treatment 9.4864908E7 990000.0 0.09 9.6773874E7 3930000.0 0.34 0.3033 0.8569 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E20 compound treatment 7.5435718E7 -1.84E7 -1.59 8.0171954E7 -1.27E7 -1.11 -1.9107 -0.9844 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E21 compound treatment 8.0821542E7 -1.31E7 -1.13 7.6616869E7 -1.62E7 -1.42 -1.8018 -0.9934 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E22 compound treatment 9.07847E7 -3090000.0 -0.27 8.9391652E7 -3460000.0 -0.3 -0.4027 -0.9981 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E23 compound treatment 1.02608013E8 8730000.0 0.75 1.01956902E8 9110000.0 0.8 1.097 0.9996 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 E24 compound treatment 8.6440154E7 -7440000.0 -0.64 8.1858228E7 -1.1E7 -0.96 -1.1342 -0.9807 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F01 mock treatment 1.05775821E8 1.19E7 1.03 1.03900604E8 1.11E7 0.97 1.4108 0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F02 mock treatment 9.6327877E7 2450000.0 0.21 9.8930793E7 6080000.0 0.53 0.5262 0.9185 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F03 compound treatment 8.0495314E7 -1.34E7 -1.16 7.908698E7 -1.38E7 -1.2 -1.6688 -0.9998 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F04 compound treatment 5.5618135E7 -3.83E7 -3.3 5.2553292E7 -4.03E7 -3.53 -4.8302 -0.9995 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F05 compound treatment 7.2589567E7 -2.13E7 -1.84 7.3018881E7 -1.98E7 -1.74 -2.5272 -0.9996 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F06 compound treatment 4.8929926E7 -4.49E7 -3.88 4.2546914E7 -5.03E7 -4.4 -5.8579 -0.998 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F07 compound treatment 6.036064E7 -3.35E7 -2.89 5.9362172E7 -3.35E7 -2.93 -4.1192 -1.0 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F08 compound treatment 6.0710715E7 -3.32E7 -2.86 5.7871325E7 -3.5E7 -3.06 -4.1901 -0.9994 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F09 mock treatment 9.4441196E7 566000.0 0.05 9.1095419E7 -1750000.0 -0.15 -0.0739 -0.4591 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F10 mock treatment 8.7508998E7 -6370000.0 -0.55 8.5798797E7 -7050000.0 -0.62 -0.8251 -0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F11 compound treatment 8.3673398E7 -1.02E7 -0.88 8.1535019E7 -1.13E7 -0.99 -1.3232 -0.9983 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F12 compound treatment 7.5307944E7 -1.86E7 -1.6 7.6611164E7 -1.62E7 -1.42 -2.1388 -0.9982 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F13 compound treatment 8.1754185E7 -1.21E7 -1.05 7.7950845E7 -1.49E7 -1.3 -1.6622 -0.9941 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F14 compound treatment 4.8224009E7 -4.57E7 -3.94 5.0717887E7 -4.21E7 -3.69 -5.3954 -0.9994 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F15 compound treatment 4.4812776E7 -4.91E7 -4.24 4.5171403E7 -4.77E7 -4.17 -5.9469 -1.0 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F16 compound treatment 6.8438679E7 -2.54E7 -2.2 6.6155075E7 -2.67E7 -2.34 -3.2054 -0.9995 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F17 mock treatment 1.03321761E8 9450000.0 0.82 1.00185682E8 7340000.0 0.64 1.031 0.993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F18 mock treatment 9.6590328E7 2720000.0 0.23 9.9255607E7 6410000.0 0.56 0.5623 0.9252 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F19 compound treatment 6.6343819E7 -2.75E7 -2.38 6.6094677E7 -2.68E7 -2.34 -3.3371 -1.0 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F20 compound treatment 6.853163E7 -2.53E7 -2.19 7.039768E7 -2.25E7 -1.96 -2.9372 -0.9985 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F21 compound treatment 2.5570737E7 -6.83E7 -5.9 2.4039473E7 -6.88E7 -6.02 -8.4299 -0.9999 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F22 compound treatment 8.0071961E7 -1.38E7 -1.19 8.0631385E7 -1.22E7 -1.07 -1.5991 -0.9985 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F23 compound treatment 6.62318E7 -2.76E7 -2.39 6.5116348E7 -2.77E7 -2.43 -3.4045 -1.0 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 F24 compound treatment 6.1188079E7 -3.27E7 -2.82 6.0918516E7 -3.19E7 -2.79 -3.9723 -1.0 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G01 compound treatment 1.02877917E8 9000000.0 0.78 9.4174663E7 1330000.0 0.12 0.6319 0.8037 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G02 compound treatment 1.04851694E8 1.1E7 0.95 1.02559126E8 9710000.0 0.85 1.2713 0.9985 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G03 mock treatment 1.00303546E8 6430000.0 0.56 9.9704038E7 6860000.0 0.6 0.8168 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G04 mock treatment 9.3802666E7 -72600.0 -0.01 9.3870098E7 1020000.0 0.09 0.0588 0.6559 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G05 compound treatment 9.7012569E7 3140000.0 0.27 9.1864831E7 -984000.0 -0.09 0.1307 0.4597 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G06 compound treatment 9.1746737E7 -2130000.0 -0.18 8.914287E7 -3710000.0 -0.32 -0.3593 -0.9639 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G07 compound treatment 9.7101812E7 3230000.0 0.28 8.8817692E7 -4030000.0 -0.35 -0.0524 -0.1166 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G08 compound treatment 9.022504E7 -3650000.0 -0.32 9.1176066E7 -1670000.0 -0.15 -0.3265 -0.9391 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G09 compound treatment 7.5421776E7 -1.85E7 -1.59 7.5533544E7 -1.73E7 -1.52 -2.1986 -0.9997 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G10 compound treatment 9.1240261E7 -2640000.0 -0.23 9.164544E7 -1200000.0 -0.11 -0.2354 -0.9387 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G11 compound treatment 9.3005603E7 -870000.0 -0.08 8.9410692E7 -3440000.0 -0.3 -0.2659 -0.8573 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G12 compound treatment 8.8757568E7 -5120000.0 -0.44 8.8695154E7 -4150000.0 -0.36 -0.5696 -0.9953 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G13 compound treatment 9.2388088E7 -1490000.0 -0.13 9.159039E7 -1260000.0 -0.11 -0.1687 -0.9971 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G14 compound treatment 8.8532927E7 -5340000.0 -0.46 8.9272729E7 -3580000.0 -0.31 -0.5476 -0.9821 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G15 compound treatment 9.3223113E7 -652000.0 -0.06 9.2447975E7 -401000.0 -0.04 -0.0646 -0.974 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G16 compound treatment 9.1646685E7 -2230000.0 -0.19 8.729546E7 -5550000.0 -0.49 -0.4798 -0.9178 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G17 compound treatment 1.00054269E8 6180000.0 0.53 9.701893E7 4170000.0 0.36 0.6354 0.9828 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G18 compound treatment 8.3921729E7 -9950000.0 -0.86 8.1390604E7 -1.15E7 -1.0 -1.317 -0.9971 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G19 mock treatment 9.8209021E7 4330000.0 0.37 9.8308917E7 5460000.0 0.48 0.6026 0.9927 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G20 mock treatment 9.7531463E7 3660000.0 0.32 9.8482281E7 5630000.0 0.49 0.5719 0.9768 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G21 compound treatment 1.04612936E8 1.07E7 0.93 9.6962731E7 4110000.0 0.36 0.9104 0.9151 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G22 compound treatment 9.3637931E7 -237000.0 -0.02 9.2312201E7 -537000.0 -0.05 -0.0477 -0.931 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G23 compound treatment 1.01481922E8 7610000.0 0.66 9.8886484E7 6040000.0 0.53 0.8382 0.9942 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 G24 compound treatment 1.10280385E8 1.64E7 1.42 1.0336395E8 1.05E7 0.92 1.6527 0.9782 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H01 compound treatment 8.9110888E7 -4760000.0 -0.41 8.5378962E7 -7470000.0 -0.65 -0.7532 -0.9751 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H02 compound treatment 8.1055959E7 -1.28E7 -1.11 7.750718E7 -1.53E7 -1.34 -1.7323 -0.9954 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H03 mock treatment 1.02456917E8 8580000.0 0.74 9.9048063E7 6200000.0 0.54 0.9078 0.9882 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H04 mock treatment 9.0884343E7 -2990000.0 -0.26 9.4053046E7 1200000.0 0.11 -0.1081 -0.3876 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H05 compound treatment 8.5623446E7 -8250000.0 -0.71 8.170173E7 -1.11E7 -0.98 -1.1938 -0.9881 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H06 compound treatment 6.0817993E7 -3.31E7 -2.86 5.3365183E7 -3.95E7 -3.46 -4.4624 -0.9955 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H07 compound treatment 7.5883142E7 -1.8E7 -1.55 7.1860315E7 -2.1E7 -1.84 -2.3977 -0.9965 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H08 compound treatment 7.4870228E7 -1.9E7 -1.64 7.0200122E7 -2.26E7 -1.98 -2.5623 -0.9956 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H09 compound treatment 8.0335734E7 -1.35E7 -1.17 7.4585863E7 -1.83E7 -1.6 -1.9571 -0.9882 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H10 compound treatment 8.2326146E7 -1.15E7 -1.0 8.0180876E7 -1.27E7 -1.11 -1.4893 -0.9986 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H11 compound treatment 8.4969925E7 -8910000.0 -0.77 8.1622967E7 -1.12E7 -0.98 -1.2386 -0.9927 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H12 compound treatment 7.0088484E7 -2.38E7 -2.05 6.7746328E7 -2.51E7 -2.2 -3.0062 -0.9994 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H13 compound treatment 8.1165853E7 -1.27E7 -1.1 7.7689195E7 -1.52E7 -1.33 -1.7144 -0.9956 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H14 compound treatment 8.517822E7 -8700000.0 -0.75 7.9712559E7 -1.31E7 -1.15 -1.3441 -0.9787 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H15 compound treatment 9.0213736E7 -3660000.0 -0.32 8.3612293E7 -9240000.0 -0.81 -0.7952 -0.9161 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H16 compound treatment 7.7174259E7 -1.67E7 -1.44 7.3793768E7 -1.91E7 -1.67 -2.1992 -0.9974 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H17 compound treatment 9.6689319E7 2810000.0 0.24 9.4268306E7 1420000.0 0.12 0.2597 0.9515 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H18 compound treatment 8.4566538E7 -9310000.0 -0.8 8.1977108E7 -1.09E7 -0.95 -1.2413 -0.9965 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H19 mock treatment 9.8745474E7 4870000.0 0.42 9.8075261E7 5230000.0 0.46 0.6209 0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H20 mock treatment 9.4857763E7 982000.0 0.08 9.4458601E7 1610000.0 0.14 0.1596 0.9705 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H21 compound treatment 8.9324375E7 -4550000.0 -0.39 8.2435817E7 -1.04E7 -0.91 -0.9223 -0.9293 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H22 compound treatment 6.2906318E7 -3.1E7 -2.67 6.1450701E7 -3.14E7 -2.75 -3.8345 -0.9999 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H23 compound treatment 9.0975969E7 -2900000.0 -0.25 8.4874205E7 -7970000.0 -0.7 -0.6706 -0.9044 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 H24 compound treatment 9.8933127E7 5060000.0 0.44 9.1698448E7 -1150000.0 -0.1 0.2377 0.5303 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I01 compound treatment 1.03214009E8 9340000.0 0.81 9.9163285E7 6310000.0 0.55 0.9611 0.983 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I02 compound treatment 1.00622115E8 6750000.0 0.58 9.6192043E7 3340000.0 0.29 0.619 0.9492 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I03 compound treatment 9.6079254E7 2200000.0 0.19 9.7030093E7 4180000.0 0.37 0.3934 0.9536 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I04 compound treatment 8.977439E7 -4100000.0 -0.35 9.3300643E7 452000.0 0.04 -0.2225 -0.6243 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I05 mock treatment 9.240057E7 -1470000.0 -0.13 9.6426797E7 3580000.0 0.31 0.1314 0.3886 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I06 mock treatment 9.0377494E7 -3500000.0 -0.3 9.2844251E7 -4500.0 0.0 -0.2139 -0.708 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I07 compound treatment 9.5102281E7 1230000.0 0.11 9.3549442E7 701000.0 0.06 0.1183 0.9662 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I08 compound treatment 9.1158609E7 -2720000.0 -0.23 9.0323583E7 -2530000.0 -0.22 -0.3222 -0.9996 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I09 compound treatment 9.210662E7 -1770000.0 -0.15 9.2632125E7 -217000.0 -0.02 -0.1214 -0.7888 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I10 compound treatment 9.0366428E7 -3510000.0 -0.3 8.7821587E7 -5030000.0 -0.44 -0.5254 -0.9834 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I11 compound treatment 8.8242015E7 -5630000.0 -0.49 9.101363E7 -1840000.0 -0.16 -0.4576 -0.8931 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I12 compound treatment 7.5139376E7 -1.87E7 -1.62 7.7583554E7 -1.53E7 -1.34 -2.089 -0.9955 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I13 compound treatment 8.7669657E7 -6210000.0 -0.54 8.5669756E7 -7180000.0 -0.63 -0.8233 -0.9969 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I14 compound treatment 9.0355361E7 -3520000.0 -0.3 9.2508806E7 -340000.0 -0.03 -0.236 -0.7726 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I15 compound treatment 8.5328499E7 -8550000.0 -0.74 8.6774633E7 -6070000.0 -0.53 -0.8979 -0.987 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I16 compound treatment 8.4270727E7 -9600000.0 -0.83 8.0953762E7 -1.19E7 -1.04 -1.3227 -0.9937 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I17 compound treatment 8.5691038E7 -8180000.0 -0.71 8.7899833E7 -4950000.0 -0.43 -0.8061 -0.9724 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I18 compound treatment 8.03673E7 -1.35E7 -1.17 8.0270014E7 -1.26E7 -1.1 -1.6034 -0.9996 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I19 compound treatment 9.5872733E7 2000000.0 0.17 9.6568965E7 3720000.0 0.33 0.3522 0.9559 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I20 compound treatment 8.6765472E7 -7110000.0 -0.61 8.4285075E7 -8560000.0 -0.75 -0.9642 -0.9951 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I21 mock treatment 9.4964238E7 1090000.0 0.09 9.8214404E7 5370000.0 0.47 0.3986 0.8322 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I22 mock treatment 9.4684778E7 809000.0 0.07 9.5751386E7 2900000.0 0.25 0.2291 0.8694 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I23 compound treatment 8.8351895E7 -5520000.0 -0.48 1.03627887E8 1.08E7 0.94 0.3297 0.3119 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 I24 compound treatment 8.2188444E7 -1.17E7 -1.01 9.5597423E7 2750000.0 0.24 -0.5437 -0.5239 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J01 compound treatment 1.02129107E8 8250000.0 0.71 9.6299567E7 3450000.0 0.3 0.7176 0.9269 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J02 compound treatment 8.1418678E7 -1.25E7 -1.08 8.1855786E7 -1.1E7 -0.96 -1.4411 -0.9984 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J03 compound treatment 9.1063494E7 -2810000.0 -0.24 9.4496828E7 1650000.0 0.14 -0.0697 -0.2469 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J04 compound treatment 8.393197E7 -9940000.0 -0.86 8.6423643E7 -6430000.0 -0.56 -1.0049 -0.9789 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J05 mock treatment 9.4770139E7 895000.0 0.08 9.6595867E7 3750000.0 0.33 0.2865 0.8505 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J06 mock treatment 8.7497537E7 -6380000.0 -0.55 8.7589257E7 -5260000.0 -0.46 -0.715 -0.996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J07 compound treatment 7.8791884E7 -1.51E7 -1.3 6.9925262E7 -2.29E7 -2.01 -2.3398 -0.9781 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J08 compound treatment 9.0473356E7 -3400000.0 -0.29 9.0294282E7 -2550000.0 -0.22 -0.3659 -0.9909 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J09 compound treatment 7.1194516E7 -2.27E7 -1.96 6.7685654E7 -2.52E7 -2.2 -2.9424 -0.9983 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J10 compound treatment 8.0699067E7 -1.32E7 -1.14 8.0775934E7 -1.21E7 -1.06 -1.5518 -0.9993 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J11 compound treatment 8.7400127E7 -6480000.0 -0.56 9.047106E7 -2380000.0 -0.21 -0.5426 -0.9093 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J12 compound treatment 7.1958242E7 -2.19E7 -1.89 7.4920937E7 -1.79E7 -1.57 -2.448 -0.9956 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J13 compound treatment 8.0338851E7 -1.35E7 -1.17 7.815076E7 -1.47E7 -1.29 -1.7363 -0.9989 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J14 compound treatment 8.8878513E7 -5000000.0 -0.43 8.9790914E7 -3060000.0 -0.27 -0.4944 -0.9736 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J15 compound treatment 6.7438358E7 -2.64E7 -2.28 6.6874066E7 -2.6E7 -2.27 -3.222 -1.0 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J16 compound treatment 9.071196E7 -3160000.0 -0.27 9.0980143E7 -1870000.0 -0.16 -0.3088 -0.9699 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J17 compound treatment 9.4241883E7 367000.0 0.03 9.0850961E7 -2000000.0 -0.17 -0.1012 -0.5698 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J18 compound treatment 8.3174157E7 -1.07E7 -0.92 8.107909E7 -1.18E7 -1.03 -1.3819 -0.9985 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J19 compound treatment 7.788887E7 -1.6E7 -1.38 7.638676E7 -1.65E7 -1.44 -1.9951 -0.9998 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J20 compound treatment 8.5539821E7 -8340000.0 -0.72 8.5735952E7 -7110000.0 -0.62 -0.9493 -0.9974 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J21 mock treatment 9.741213E7 3540000.0 0.31 9.98755E7 7030000.0 0.61 0.6509 0.9479 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J22 mock treatment 9.4514228E7 639000.0 0.06 9.4764441E7 1920000.0 0.17 0.1576 0.8927 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J23 compound treatment 7.8622872E7 -1.53E7 -1.32 1.03390574E8 1.05E7 0.92 -0.2792 -0.1736 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 J24 compound treatment 8.0200301E7 -1.37E7 -1.18 8.7742197E7 -5110000.0 -0.45 -1.1512 -0.9116 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K01 compound treatment 8.1976456E7 -1.19E7 -1.03 8.0639484E7 -1.22E7 -1.07 -1.4823 -0.9998 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K02 compound treatment 9.0100543E7 -3770000.0 -0.33 9.0146103E7 -2700000.0 -0.24 -0.3978 -0.9876 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K03 compound treatment 8.8579162E7 -5300000.0 -0.46 9.7005294E7 4160000.0 0.36 -0.0662 -0.1133 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K04 compound treatment 7.653492E7 -1.73E7 -1.5 9.0724322E7 -2120000.0 -0.19 -1.1905 -0.7888 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K05 compound treatment 9.3963486E7 88200.0 0.01 9.7955511E7 5110000.0 0.45 0.3214 0.7191 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K06 compound treatment 9.2604233E7 -1270000.0 -0.11 8.9862818E7 -2990000.0 -0.26 -0.2624 -0.9258 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K07 mock treatment 9.3377556E7 -498000.0 -0.04 9.4139843E7 1290000.0 0.11 0.0495 0.4094 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K08 mock treatment 8.2851859E7 -1.1E7 -0.95 8.8502655E7 -4350000.0 -0.38 -0.9422 -0.919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K09 compound treatment 8.7849463E7 -6030000.0 -0.52 8.7342509E7 -5510000.0 -0.48 -0.7088 -0.9993 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K10 compound treatment 8.6969903E7 -6910000.0 -0.6 7.5294799E7 -1.76E7 -1.54 -1.5081 -0.9151 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K11 compound treatment 8.3163395E7 -1.07E7 -0.93 8.286819E7 -9980000.0 -0.87 -1.2719 -0.9996 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K12 compound treatment 8.7557089E7 -6320000.0 -0.55 8.6485815E7 -6360000.0 -0.56 -0.7796 -0.9999 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K13 compound treatment 8.8285239E7 -5590000.0 -0.48 9.0013324E7 -2840000.0 -0.25 -0.5169 -0.9521 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K14 compound treatment 4.7406483E7 -4.65E7 -4.01 4.7645386E7 -4.52E7 -3.96 -5.6354 -1.0 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K15 mock treatment 8.4671552E7 -9200000.0 -0.79 9.4553428E7 1700000.0 0.15 -0.4566 -0.5645 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K16 mock treatment 7.6332923E7 -1.75E7 -1.52 9.2747801E7 -101000.0 -0.01 -1.0776 -0.7112 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K17 compound treatment 9.6899131E7 3020000.0 0.26 9.1322871E7 -1530000.0 -0.13 0.0903 0.3077 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K18 compound treatment 8.1650974E7 -1.22E7 -1.06 8.0207581E7 -1.26E7 -1.11 -1.5289 -0.9997 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K19 compound treatment 9.256848E7 -1310000.0 -0.11 9.2603566E7 -245000.0 -0.02 -0.095 -0.8267 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K20 compound treatment 8.9756896E7 -4120000.0 -0.36 8.6151719E7 -6700000.0 -0.59 -0.666 -0.9714 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K21 compound treatment 1.07918385E8 1.4E7 1.21 1.04783245E8 1.19E7 1.04 1.5962 0.9972 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K22 compound treatment 9.988646E7 6010000.0 0.52 1.00757185E8 7910000.0 0.69 0.8565 0.99 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K23 mock treatment 9.8804093E7 4930000.0 0.43 9.867371E7 5820000.0 0.51 0.6615 0.996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 K24 mock treatment 1.01646188E8 7770000.0 0.67 9.8381661E7 5530000.0 0.48 0.817 0.9872 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L01 compound treatment 1.00397111E8 6520000.0 0.56 9.7962039E7 5110000.0 0.45 0.7147 0.9935 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L02 compound treatment 8.9453047E7 -4420000.0 -0.38 9.0045661E7 -2800000.0 -0.25 -0.4436 -0.9771 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L03 compound treatment 7.8673398E7 -1.52E7 -1.31 1.00724391E8 7880000.0 0.69 -0.4411 -0.2974 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L04 compound treatment 6.6548929E7 -2.73E7 -2.36 7.9030688E7 -1.38E7 -1.21 -2.5241 -0.9518 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L05 compound treatment 9.1375384E7 -2500000.0 -0.22 9.113969E7 -1710000.0 -0.15 -0.2584 -0.9839 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L06 compound treatment 8.094606E7 -1.29E7 -1.12 8.5222297E7 -7630000.0 -0.67 -1.2616 -0.9697 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L07 mock treatment 9.6676805E7 2800000.0 0.24 8.7425106E7 -5420000.0 -0.47 -0.1645 -0.3088 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L08 mock treatment 8.5861871E7 -8010000.0 -0.69 8.7697272E7 -5150000.0 -0.45 -0.8082 -0.9784 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L09 compound treatment 9.2262535E7 -1610000.0 -0.14 9.1242786E7 -1610000.0 -0.14 -0.1979 -1.0 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L10 compound treatment 7.5233092E7 -1.86E7 -1.61 8.2976899E7 -9870000.0 -0.86 -1.7495 -0.9574 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L11 compound treatment 9.083627E7 -3040000.0 -0.26 8.7303008E7 -5550000.0 -0.49 -0.5288 -0.9584 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L12 compound treatment 7.7875592E7 -1.6E7 -1.38 8.0451837E7 -1.24E7 -1.08 -1.7443 -0.9928 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L13 compound treatment 8.9039334E7 -4840000.0 -0.42 8.4975489E7 -7870000.0 -0.69 -0.7826 -0.9712 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L14 compound treatment 8.19684E7 -1.19E7 -1.03 8.6345669E7 -6500000.0 -0.57 -1.1296 -0.9611 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L15 mock treatment 7.6392056E7 -1.75E7 -1.51 9.3466314E7 618000.0 0.05 -1.0296 -0.6814 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L16 mock treatment 7.5229225E7 -1.86E7 -1.61 9.2334589E7 -514000.0 -0.04 -1.1706 -0.7266 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L17 compound treatment 7.7151611E7 -1.67E7 -1.44 7.4242064E7 -1.86E7 -1.63 -2.1729 -0.9982 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L18 compound treatment 8.8103336E7 -5770000.0 -0.5 9.1389031E7 -1460000.0 -0.13 -0.4429 -0.8605 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L19 compound treatment 1.008166E8 6940000.0 0.6 9.5732245E7 2880000.0 0.25 0.6024 0.926 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L20 compound treatment 9.0688199E7 -3190000.0 -0.28 9.363129E7 783000.0 0.07 -0.1462 -0.5155 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L21 compound treatment 1.02690264E8 8810000.0 0.76 1.02744777E8 9900000.0 0.87 1.1508 0.9979 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L22 compound treatment 9.0909083E7 -2970000.0 -0.26 8.530847E7 -7540000.0 -0.66 -0.6478 -0.9151 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L23 mock treatment 9.4888461E7 1010000.0 0.09 1.00903962E8 8060000.0 0.7 0.5604 0.7888 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 L24 mock treatment 1.03614772E8 9740000.0 0.84 1.02117607E8 9270000.0 0.81 1.1684 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M01 compound treatment 7.536061E7 -1.85E7 -1.6 7.4186034E7 -1.87E7 -1.63 -2.2857 -0.9999 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M02 compound treatment 9.3490573E7 -385000.0 -0.03 8.6869821E7 -5980000.0 -0.52 -0.3935 -0.7505 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M03 compound treatment 8.4573068E7 -9300000.0 -0.8 9.0304927E7 -2540000.0 -0.22 -0.7256 -0.8702 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M04 compound treatment 9.9568542E7 5690000.0 0.49 9.3408897E7 560000.0 0.05 0.3824 0.7738 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M05 compound treatment 9.6474491E7 2600000.0 0.22 9.1325801E7 -1520000.0 -0.13 0.0645 0.247 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M06 compound treatment 8.529232E7 -8580000.0 -0.74 9.4106274E7 1260000.0 0.11 -0.4464 -0.5956 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M07 compound treatment 7.3088121E7 -2.08E7 -1.8 7.0768935E7 -2.21E7 -1.93 -2.636 -0.9993 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M08 compound treatment 7.9199255E7 -1.47E7 -1.27 7.3695561E7 -1.92E7 -1.68 -2.0816 -0.9905 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M09 mock treatment 8.3853091E7 -1.0E7 -0.87 9.158293E7 -1270000.0 -0.11 -0.6904 -0.7911 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M10 mock treatment 8.8417563E7 -5460000.0 -0.47 8.9399315E7 -3450000.0 -0.3 -0.5468 -0.9768 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M11 compound treatment 5.0389453E7 -4.35E7 -3.76 4.700785E7 -4.58E7 -4.01 -5.4927 -0.9995 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M12 compound treatment 7.7949107E7 -1.59E7 -1.38 8.6857237E7 -5990000.0 -0.52 -1.3435 -0.9126 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M13 mock treatment 8.9031055E7 -4840000.0 -0.42 9.2777333E7 -71400.0 -0.01 -0.3003 -0.7176 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M14 mock treatment 9.19247E7 -1950000.0 -0.17 8.4535151E7 -8310000.0 -0.73 -0.6336 -0.8484 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M15 compound treatment 4.2351857E7 -5.15E7 -4.45 5.474075E7 -3.81E7 -3.34 -5.5051 -0.9899 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M16 compound treatment 6.6271579E7 -2.76E7 -2.38 6.7440764E7 -2.54E7 -2.22 -3.2582 -0.9994 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M17 compound treatment 9.8833603E7 4960000.0 0.43 9.3191697E7 343000.0 0.03 0.324 0.7548 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M18 compound treatment 8.5191452E7 -8680000.0 -0.75 8.7953482E7 -4900000.0 -0.43 -0.8333 -0.9647 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M19 compound treatment 9.2627325E7 -1250000.0 -0.11 9.1850863E7 -998000.0 -0.09 -0.138 -0.9945 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M20 compound treatment 9.1534838E7 -2340000.0 -0.2 8.510893E7 -7740000.0 -0.68 -0.6219 -0.8798 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M21 compound treatment 7.9487282E7 -1.44E7 -1.24 1.05773282E8 1.29E7 1.13 -0.0789 -0.047 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M22 compound treatment 7.924128E7 -1.46E7 -1.26 8.6352981E7 -6500000.0 -0.57 -1.2958 -0.9349 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M23 compound treatment 8.5425991E7 -8450000.0 -0.73 8.1056502E7 -1.18E7 -1.03 -1.2458 -0.9856 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 M24 compound treatment 7.7948558E7 -1.59E7 -1.38 7.7344217E7 -1.55E7 -1.36 -1.9322 -1.0 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N01 compound treatment 8.9788178E7 -4090000.0 -0.35 1.04416353E8 1.16E7 1.01 0.4662 0.4349 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N02 compound treatment 8.6689832E7 -7190000.0 -0.62 8.5609719E7 -7240000.0 -0.63 -0.8868 -0.9999 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N03 compound treatment 9.7920276E7 4040000.0 0.35 9.99967E7 7150000.0 0.63 0.6894 0.9621 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N04 compound treatment 9.3207557E7 -668000.0 -0.06 9.6321324E7 3470000.0 0.3 0.1741 0.5629 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N05 compound treatment 9.3419593E7 -456000.0 -0.04 8.7785352E7 -5060000.0 -0.44 -0.3412 -0.7669 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N06 compound treatment 8.8417839E7 -5460000.0 -0.47 8.8969905E7 -3880000.0 -0.34 -0.5734 -0.987 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N07 compound treatment 9.3341598E7 -534000.0 -0.05 9.4931154E7 2080000.0 0.18 0.0963 0.5121 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N08 compound treatment 7.4879118E7 -1.9E7 -1.64 7.579988E7 -1.7E7 -1.49 -2.2152 -0.9989 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N09 mock treatment 9.3387217E7 -488000.0 -0.04 8.2278461E7 -1.06E7 -0.93 -0.6839 -0.7386 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N10 mock treatment 8.6576489E7 -7300000.0 -0.63 8.930514E7 -3540000.0 -0.31 -0.6651 -0.9466 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N11 compound treatment 8.6652481E7 -7220000.0 -0.62 6.4646894E7 -2.82E7 -2.47 -2.1864 -0.8588 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N12 compound treatment 6.2591195E7 -3.13E7 -2.7 6.0205529E7 -3.26E7 -2.86 -3.9308 -0.9996 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N13 mock treatment 8.6647745E7 -7230000.0 -0.62 9.1847246E7 -1000000.0 -0.09 -0.5034 -0.7986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N14 mock treatment 8.8021598E7 -5850000.0 -0.51 8.4207354E7 -8640000.0 -0.76 -0.8923 -0.9808 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N15 compound treatment 8.4680033E7 -9200000.0 -0.79 7.253639E7 -2.03E7 -1.78 -1.8186 -0.934 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N16 compound treatment 6.9560463E7 -2.43E7 -2.1 6.8823907E7 -2.4E7 -2.1 -2.9718 -1.0 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N17 compound treatment 9.5114212E7 1240000.0 0.11 9.0818314E7 -2030000.0 -0.18 -0.05 -0.241 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N18 compound treatment 6.8815914E7 -2.51E7 -2.16 7.574439E7 -1.71E7 -1.5 -2.589 -0.9838 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N19 compound treatment 9.6347162E7 2470000.0 0.21 9.7525074E7 4680000.0 0.41 0.4404 0.954 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N20 compound treatment 6.9730147E7 -2.41E7 -2.09 6.4172381E7 -2.87E7 -2.51 -3.2493 -0.9958 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N21 compound treatment 7.4122651E7 -1.98E7 -1.71 1.00064781E8 7220000.0 0.63 -0.7598 -0.4177 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N22 compound treatment 5.490133E7 -3.9E7 -3.37 6.6017118E7 -2.68E7 -2.35 -4.0408 -0.9845 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N23 compound treatment 9.9468984E7 5590000.0 0.48 9.4067604E7 1220000.0 0.11 0.4171 0.8429 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 N24 compound treatment 9.5924665E7 2050000.0 0.18 1.04261947E8 1.14E7 1.0 0.8315 0.8196 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O01 compound treatment 6.2660012E7 -3.12E7 -2.7 6.0808424E7 -3.2E7 -2.8 -3.8893 -0.9998 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O02 compound treatment 7.9150719E7 -1.47E7 -1.27 7.9785794E7 -1.31E7 -1.14 -1.7077 -0.9986 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O03 compound treatment 9.9270201E7 5390000.0 0.47 7.4577704E7 -1.83E7 -1.6 -0.8012 -0.481 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O04 compound treatment 8.0883177E7 -1.3E7 -1.12 9.3486734E7 638000.0 0.06 -0.754 -0.6711 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O05 compound treatment 7.5057712E7 -1.88E7 -1.63 7.6976454E7 -1.59E7 -1.39 -2.1315 -0.9969 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O06 compound treatment 9.5449859E7 1570000.0 0.14 9.1077108E7 -1770000.0 -0.16 -0.0135 -0.0653 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O07 compound treatment 8.9928933E7 -3950000.0 -0.34 8.7097676E7 -5750000.0 -0.5 -0.5969 -0.982 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O08 compound treatment 9.0540487E7 -3330000.0 -0.29 8.9634202E7 -3210000.0 -0.28 -0.4026 -0.9999 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O09 compound treatment 7.9458981E7 -1.44E7 -1.25 8.846948E7 -4380000.0 -0.38 -1.1515 -0.8838 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O10 compound treatment 7.4970843E7 -1.89E7 -1.63 7.2759155E7 -2.01E7 -1.76 -2.3978 -0.9993 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O11 mock treatment 8.975808E7 -4120000.0 -0.36 8.3170618E7 -9680000.0 -0.85 -0.8504 -0.9257 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O12 mock treatment 8.5294612E7 -8580000.0 -0.74 8.5300556E7 -7550000.0 -0.66 -0.9912 -0.9984 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O13 compound treatment 7.9491164E7 -1.44E7 -1.24 8.1767638E7 -1.11E7 -0.97 -1.5643 -0.9925 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O14 compound treatment 8.279822E7 -1.11E7 -0.96 7.9766339E7 -1.31E7 -1.14 -1.4861 -0.996 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O15 compound treatment 9.3950147E7 74800.0 0.01 9.0609937E7 -2240000.0 -0.2 -0.134 -0.6834 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O16 compound treatment 8.9790848E7 -4080000.0 -0.35 8.7603342E7 -5250000.0 -0.46 -0.5741 -0.9915 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O17 compound treatment 9.8224876E7 4350000.0 0.38 9.3892345E7 1040000.0 0.09 0.3302 0.8541 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O18 compound treatment 8.6251413E7 -7620000.0 -0.66 8.4748661E7 -8100000.0 -0.71 -0.9669 -0.9993 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O19 compound treatment 9.9305218E7 5430000.0 0.47 1.0190634E8 9060000.0 0.79 0.8922 0.9686 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O20 compound treatment 9.5110222E7 1230000.0 0.11 9.0067852E7 -2780000.0 -0.24 -0.0967 -0.3638 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O21 compound treatment 1.01113248E8 7240000.0 0.63 9.7742991E7 4890000.0 0.43 0.7449 0.983 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O22 compound treatment 8.6839731E7 -7040000.0 -0.61 8.066162E7 -1.22E7 -1.07 -1.1839 -0.9644 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O23 compound treatment 9.0697044E7 -3180000.0 -0.27 9.031501E7 -2530000.0 -0.22 -0.3509 -0.9944 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 O24 compound treatment 9.289648E7 -979000.0 -0.08 8.6215055E7 -6630000.0 -0.58 -0.4703 -0.8016 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P01 compound treatment 9.9737246E7 5860000.0 0.51 7.8911474E7 -1.39E7 -1.22 -0.5045 -0.382 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P02 compound treatment 8.2030099E7 -1.18E7 -1.02 8.3091791E7 -9760000.0 -0.85 -1.3272 -0.996 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P03 compound treatment 9.9536953E7 5660000.0 0.49 7.9258089E7 -1.36E7 -1.19 -0.4953 -0.3851 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P04 compound treatment 7.2872632E7 -2.1E7 -1.81 8.4503752E7 -8340000.0 -0.73 -1.7992 -0.92 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P05 compound treatment 9.7457124E7 3580000.0 0.31 9.6214982E7 3370000.0 0.29 0.4271 0.9997 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P06 compound treatment 6.5266507E7 -2.86E7 -2.47 6.4181544E7 -2.87E7 -2.51 -3.5213 -1.0 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P07 compound treatment 9.5695375E7 1820000.0 0.16 9.5276169E7 2430000.0 0.21 0.2614 0.989 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P08 compound treatment 7.2268537E7 -2.16E7 -1.87 6.7933607E7 -2.49E7 -2.18 -2.8615 -0.997 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P09 compound treatment 9.3281187E7 -594000.0 -0.05 8.2940183E7 -9910000.0 -0.87 -0.6495 -0.7476 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P10 compound treatment 7.7772938E7 -1.61E7 -1.39 7.6595361E7 -1.63E7 -1.42 -1.9893 -0.9999 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P11 mock treatment 9.3257372E7 -618000.0 -0.05 9.1106823E7 -1740000.0 -0.15 -0.1455 -0.901 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P12 mock treatment 9.1961239E7 -1910000.0 -0.17 8.6815547E7 -6030000.0 -0.53 -0.4903 -0.8861 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P13 compound treatment 9.7095221E7 3220000.0 0.28 7.7087829E7 -1.58E7 -1.38 -0.7787 -0.5534 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P14 compound treatment 9.0428742E7 -3450000.0 -0.3 9.0864606E7 -1980000.0 -0.17 -0.3333 -0.9671 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P15 compound treatment 7.3631995E7 -2.02E7 -1.75 6.6251527E7 -2.66E7 -2.33 -2.8823 -0.9901 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P16 compound treatment 9.1945635E7 -1930000.0 -0.17 8.485683E7 -7990000.0 -0.7 -0.6124 -0.8518 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P17 compound treatment 9.467302E7 798000.0 0.07 9.32843E7 436000.0 0.04 0.0757 0.961 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P18 compound treatment 9.429109E7 416000.0 0.04 8.9432149E7 -3420000.0 -0.3 -0.186 -0.6177 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P19 compound treatment 1.00103382E8 6230000.0 0.54 9.7695425E7 4850000.0 0.42 0.6803 0.9931 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P20 compound treatment 9.1899624E7 -1980000.0 -0.17 8.5303836E7 -7540000.0 -0.66 -0.5876 -0.8615 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P21 compound treatment 9.8812576E7 4940000.0 0.43 8.961368E7 -3240000.0 -0.28 0.1013 0.198 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P22 compound treatment 9.4658411E7 783000.0 0.07 8.6827846E7 -6020000.0 -0.53 -0.3248 -0.6113 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P23 compound treatment 1.03770758E8 9900000.0 0.85 1.01855367E8 9010000.0 0.79 1.1617 0.9992 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2094 P24 compound treatment 1.09269063E8 1.54E7 1.33 1.0187743E8 9030000.0 0.79 1.4989 0.9691 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A01 compound treatment 1.11298563E8 1.63E7 1.41 9.7471961E7 3880000.0 0.34 1.2337 0.8535 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A02 compound treatment 1.14557928E8 1.95E7 1.69 1.01998119E8 8410000.0 0.74 1.7129 0.9309 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A03 compound treatment 8.0208957E7 -1.48E7 -1.28 8.0312742E7 -1.33E7 -1.16 -1.727 -0.9988 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A04 compound treatment 9.8415925E7 3380000.0 0.29 1.00220645E8 6630000.0 0.58 0.617 0.9497 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A05 compound treatment 8.6828459E7 -8200000.0 -0.71 7.2475316E7 -2.11E7 -1.85 -1.8077 -0.9134 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A06 compound treatment 1.02863407E8 7830000.0 0.68 9.6200532E7 2610000.0 0.23 0.6399 0.8961 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A07 compound treatment 1.00065905E8 5030000.0 0.43 9.7127658E7 3540000.0 0.31 0.5264 0.9861 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A08 compound treatment 7.3189203E7 -2.18E7 -1.89 7.3500789E7 -2.01E7 -1.76 -2.5772 -0.9994 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A09 compound treatment 1.0071833E8 5690000.0 0.49 8.4899733E7 -8690000.0 -0.76 -0.1905 -0.2104 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A10 compound treatment 9.7436577E7 2410000.0 0.21 9.3609733E7 19000.0 0.0 0.1481 0.7127 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A11 compound treatment 8.5931147E7 -9100000.0 -0.79 8.002667E7 -1.36E7 -1.19 -1.3952 -0.98 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A12 compound treatment 9.5400874E7 370000.0 0.03 9.1541334E7 -2050000.0 -0.18 -0.1042 -0.5722 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A13 mock treatment 8.9931967E7 -5100000.0 -0.44 8.3733581E7 -9860000.0 -0.86 -0.9214 -0.9513 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A14 mock treatment 1.01618181E8 6590000.0 0.57 9.0917798E7 -2670000.0 -0.23 0.2369 0.3851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A15 compound treatment 1.02200946E8 7170000.0 0.62 9.8825871E7 5240000.0 0.46 0.7619 0.989 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A16 compound treatment 9.9030993E7 4000000.0 0.35 9.5972116E7 2380000.0 0.21 0.3917 0.9707 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A17 compound treatment 9.1868607E7 -3160000.0 -0.27 8.8660757E7 -4930000.0 -0.43 -0.4982 -0.9757 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A18 compound treatment 1.0064628E8 5620000.0 0.48 9.7973233E7 4380000.0 0.38 0.6142 0.9932 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A19 compound treatment 9.7398753E7 2370000.0 0.2 1.01202151E8 7610000.0 0.67 0.6156 0.8835 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A20 compound treatment 9.1010873E7 -4020000.0 -0.35 8.5549136E7 -8040000.0 -0.7 -0.7432 -0.947 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A21 compound treatment 9.6248384E7 1220000.0 0.11 9.3746737E7 156000.0 0.01 0.084 0.7923 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A22 compound treatment 1.09078549E8 1.4E7 1.21 1.05913924E8 1.23E7 1.08 1.6206 0.9983 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A23 compound treatment 1.1142684E8 1.64E7 1.42 1.06517207E8 1.29E7 1.13 1.8013 0.9938 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 A24 compound treatment 9.7578924E7 2550000.0 0.22 1.05048728E8 1.15E7 1.0 0.8647 0.8422 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B01 compound treatment 8.1080186E7 -1.4E7 -1.2 8.114646E7 -1.24E7 -1.09 -1.6221 -0.9987 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B02 compound treatment 1.06812197E8 1.18E7 1.02 9.8828335E7 5240000.0 0.46 1.0437 0.9351 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B03 compound treatment 9.2251689E7 -2780000.0 -0.24 1.02830081E8 9240000.0 0.81 0.402 0.4766 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B04 compound treatment 1.01421736E8 6390000.0 0.55 9.0894507E7 -2700000.0 -0.24 0.2235 0.3722 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B05 compound treatment 9.5551227E7 520000.0 0.04 9.4491854E7 901000.0 0.08 0.0875 0.9644 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B06 compound treatment 9.8856223E7 3830000.0 0.33 9.4721518E7 1130000.0 0.1 0.3036 0.8803 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B07 compound treatment 9.6006187E7 975000.0 0.08 9.927293E7 5680000.0 0.5 0.4112 0.8153 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B08 compound treatment 6.9548795E7 -2.55E7 -2.2 6.9499582E7 -2.41E7 -2.11 -3.0472 -0.9998 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B09 compound treatment 9.3501226E7 -1530000.0 -0.13 9.115565E7 -2440000.0 -0.21 -0.2441 -0.9736 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B10 compound treatment 9.6565702E7 1530000.0 0.13 8.9776911E7 -3810000.0 -0.33 -0.1423 -0.3962 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B11 compound treatment 8.761033E7 -7420000.0 -0.64 1.00325237E8 6730000.0 0.59 -0.0365 -0.0419 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B12 compound treatment 8.823418E7 -6800000.0 -0.59 8.3523252E7 -1.01E7 -0.88 -1.0381 -0.9805 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B13 mock treatment 9.1020036E7 -4010000.0 -0.35 9.3621277E7 30600.0 0.0 -0.2431 -0.7016 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B14 mock treatment 8.4531069E7 -1.05E7 -0.91 9.2334576E7 -1260000.0 -0.11 -0.719 -0.7871 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B15 compound treatment 9.3806195E7 -1220000.0 -0.11 8.9988643E7 -3600000.0 -0.32 -0.2977 -0.8953 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B16 compound treatment 9.1522179E7 -3510000.0 -0.3 8.8751579E7 -4840000.0 -0.42 -0.5138 -0.9865 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B17 compound treatment 9.4099582E7 -932000.0 -0.08 9.4919983E7 1330000.0 0.12 0.0254 0.1794 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B18 compound treatment 9.1241567E7 -3790000.0 -0.33 9.543032E7 1840000.0 0.16 -0.1176 -0.3224 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B19 compound treatment 1.0084789E8 5820000.0 0.5 1.04351811E8 1.08E7 0.94 1.0212 0.9567 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B20 compound treatment 9.0035799E7 -5000000.0 -0.43 9.1015011E7 -2580000.0 -0.23 -0.4645 -0.9542 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B21 compound treatment 1.03014375E8 7980000.0 0.69 1.03892936E8 1.03E7 0.9 1.1251 0.9912 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B22 compound treatment 9.1011618E7 -4020000.0 -0.35 1.01583401E8 7990000.0 0.7 0.2491 0.319 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B23 compound treatment 1.07126696E8 1.21E7 1.04 1.07068813E8 1.35E7 1.18 1.5728 0.9982 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 B24 compound treatment 1.08166022E8 1.31E7 1.13 9.7664357E7 4070000.0 0.36 1.0543 0.8866 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C01 compound treatment 1.05694639E8 1.07E7 0.92 9.0325922E7 -3260000.0 -0.29 0.4492 0.4658 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C02 compound treatment 1.07095117E8 1.21E7 1.04 9.9303197E7 5710000.0 0.5 1.0903 0.9434 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C03 compound treatment 9.4058957E7 -972000.0 -0.08 9.9081974E7 5490000.0 0.48 0.2804 0.5749 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C04 compound treatment 2.0962583E7 -7.41E7 -6.4 2.0418734E7 -7.32E7 -6.4 -9.0519 -1.0 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C05 compound treatment 1.01621581E8 6590000.0 0.57 8.623531E7 -7360000.0 -0.64 -0.0527 -0.0613 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C06 compound treatment 1.01890695E8 6860000.0 0.59 9.8316784E7 4730000.0 0.41 0.7114 0.9846 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C07 compound treatment 8.5590756E7 -9440000.0 -0.82 9.2758422E7 -832000.0 -0.07 -0.6281 -0.7672 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C08 compound treatment 7.0514251E7 -2.45E7 -2.12 6.821517E7 -2.54E7 -2.22 -3.0677 -0.9997 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C09 compound treatment 9.5833358E7 802000.0 0.07 8.2775634E7 -1.08E7 -0.95 -0.6203 -0.6536 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C10 compound treatment 2.3045451E7 -7.2E7 -6.22 2.2145533E7 -7.14E7 -6.25 -8.8178 -1.0 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C11 mock treatment 8.3493527E7 -1.15E7 -1.0 9.2160407E7 -1430000.0 -0.13 -0.7932 -0.7897 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C12 mock treatment 9.1874332E7 -3160000.0 -0.27 8.7101121E7 -6490000.0 -0.57 -0.5944 -0.9435 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C13 compound treatment 9.7311689E7 2280000.0 0.2 8.6552613E7 -7040000.0 -0.62 -0.2963 -0.4581 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C14 compound treatment 9.4738443E7 -293000.0 -0.03 9.2907935E7 -683000.0 -0.06 -0.0601 -0.9267 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C15 mock treatment 9.4030353E7 -1000000.0 -0.09 9.5360986E7 1770000.0 0.15 0.0484 0.273 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C16 mock treatment 9.7452429E7 2420000.0 0.21 9.245386E7 -1140000.0 -0.1 0.0775 0.3348 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C17 compound treatment 8.7748821E7 -7280000.0 -0.63 8.1218282E7 -1.24E7 -1.08 -1.2104 -0.9666 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C18 compound treatment 1.03660137E8 8630000.0 0.75 1.00890981E8 7300000.0 0.64 0.9788 0.9971 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C19 compound treatment 9.9125876E7 4090000.0 0.35 9.9375932E7 5790000.0 0.51 0.6081 0.9846 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C20 compound treatment 9.6470812E7 1440000.0 0.12 9.7618534E7 4030000.0 0.35 0.3372 0.9021 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C21 compound treatment 1.06813552E8 1.18E7 1.02 9.2917805E7 -673000.0 -0.06 0.678 0.6651 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C22 compound treatment 1.0536268E8 1.03E7 0.89 1.02923491E8 9330000.0 0.82 1.2085 0.999 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C23 compound treatment 1.08417175E8 1.34E7 1.16 1.05599296E8 1.2E7 1.05 1.5607 0.9989 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 C24 compound treatment 1.0130486E8 6270000.0 0.54 1.02243322E8 8650000.0 0.76 0.9186 0.9865 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D01 compound treatment 8.6195159E7 -8840000.0 -0.76 8.5392922E7 -8200000.0 -0.72 -1.047 -0.9995 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D02 compound treatment 8.3236842E7 -1.18E7 -1.02 7.30912E7 -2.05E7 -1.79 -1.9889 -0.964 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D03 compound treatment 1.05823793E8 1.08E7 0.93 1.01649697E8 8060000.0 0.71 1.1579 0.9905 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D04 compound treatment 1.01362315E8 6330000.0 0.55 9.7675687E7 4080000.0 0.36 0.6395 0.9788 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D05 compound treatment 9.1129164E7 -3900000.0 -0.34 8.4419651E7 -9170000.0 -0.8 -0.8059 -0.9257 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D06 compound treatment 9.476929E7 -262000.0 -0.02 8.8148902E7 -5440000.0 -0.48 -0.3528 -0.7398 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D07 compound treatment 1.00821624E8 5790000.0 0.5 9.7315446E7 3720000.0 0.33 0.5842 0.9785 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D08 compound treatment 9.6861726E7 1830000.0 0.16 9.2180957E7 -1410000.0 -0.12 0.0246 0.1225 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D09 compound treatment 8.8527319E7 -6500000.0 -0.56 8.1007324E7 -1.26E7 -1.1 -1.1759 -0.9512 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D10 compound treatment 7.2250653E7 -2.28E7 -1.97 6.7803292E7 -2.58E7 -2.26 -2.9871 -0.9977 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D11 mock treatment 9.8253863E7 3220000.0 0.28 9.6832693E7 3240000.0 0.28 0.3975 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D12 mock treatment 8.9271537E7 -5760000.0 -0.5 9.1969037E7 -1620000.0 -0.14 -0.4521 -0.874 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D13 compound treatment 8.6227997E7 -8800000.0 -0.76 8.6767151E7 -6820000.0 -0.6 -0.9599 -0.9929 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D14 compound treatment 8.8364447E7 -6670000.0 -0.58 8.7815226E7 -5780000.0 -0.51 -0.7646 -0.9979 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D15 mock treatment 9.4161762E7 -869000.0 -0.08 9.6353052E7 2760000.0 0.24 0.1179 0.4655 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D16 mock treatment 9.6336051E7 1300000.0 0.11 9.2946867E7 -644000.0 -0.06 0.0399 0.3163 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D17 compound treatment 8.9003445E7 -6030000.0 -0.52 8.2004197E7 -1.16E7 -1.01 -1.0852 -0.952 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D18 compound treatment 9.8661704E7 3630000.0 0.31 9.9038301E7 5450000.0 0.48 0.5589 0.9793 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D19 compound treatment 1.02097547E8 7070000.0 0.61 1.05444378E8 1.19E7 1.04 1.1651 0.968 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D20 compound treatment 1.00451709E8 5420000.0 0.47 1.01705671E8 8110000.0 0.71 0.8332 0.9796 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D21 compound treatment 9.584847E7 817000.0 0.07 9.4676333E7 1090000.0 0.1 0.1171 0.9893 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D22 compound treatment 8.3147979E7 -1.19E7 -1.03 8.0806848E7 -1.28E7 -1.12 -1.5169 -0.9991 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D23 compound treatment 1.11321015E8 1.63E7 1.41 1.07902289E8 1.43E7 1.25 1.8806 0.9983 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 D24 compound treatment 8.1372144E7 -1.37E7 -1.18 8.318631E7 -1.04E7 -0.91 -1.4781 -0.9918 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E01 mock treatment 1.10709606E8 1.57E7 1.35 9.9581706E7 5990000.0 0.52 1.3283 0.9147 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E02 mock treatment 1.02934381E8 7900000.0 0.68 9.8147296E7 4560000.0 0.4 0.7647 0.9672 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E03 compound treatment 1.02696143E8 7670000.0 0.66 1.00115964E8 6530000.0 0.57 0.8719 0.9973 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E04 compound treatment 9.8448529E7 3420000.0 0.3 9.6316545E7 2730000.0 0.24 0.3774 0.9944 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E05 compound treatment 9.6936981E7 1910000.0 0.16 9.6277776E7 2690000.0 0.24 0.2827 0.9848 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E06 compound treatment 6.9207368E7 -2.58E7 -2.23 6.8238684E7 -2.54E7 -2.22 -3.1461 -1.0 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E07 compound treatment 9.3180003E7 -1850000.0 -0.16 9.2087858E7 -1500000.0 -0.13 -0.2061 -0.9953 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E08 compound treatment 8.9907528E7 -5120000.0 -0.44 8.9625385E7 -3970000.0 -0.35 -0.5583 -0.9928 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E09 mock treatment 9.1274822E7 -3760000.0 -0.32 9.1808962E7 -1780000.0 -0.16 -0.3397 -0.9436 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E10 mock treatment 8.8153929E7 -6880000.0 -0.59 8.8106887E7 -5480000.0 -0.48 -0.7594 -0.9944 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E11 compound treatment 8.8430075E7 -6600000.0 -0.57 9.1328801E7 -2260000.0 -0.2 -0.5431 -0.8999 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E12 compound treatment 9.0108486E7 -4920000.0 -0.43 9.189906E7 -1690000.0 -0.15 -0.4053 -0.9003 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E13 compound treatment 9.1670076E7 -3360000.0 -0.29 9.466052E7 1070000.0 0.09 -0.1391 -0.4559 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E14 compound treatment 9.0350588E7 -4680000.0 -0.4 9.1730694E7 -1860000.0 -0.16 -0.401 -0.92 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E15 compound treatment 3.9360408E7 -5.57E7 -4.81 3.7374286E7 -5.62E7 -4.92 -6.879 -0.9999 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E16 compound treatment 9.3545805E7 -1490000.0 -0.13 9.2150652E7 -1440000.0 -0.13 -0.1798 -1.0 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E17 mock treatment 1.02585615E8 7550000.0 0.65 1.01744694E8 8150000.0 0.71 0.966 0.999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E18 mock treatment 1.04004453E8 8970000.0 0.78 1.02742344E8 9150000.0 0.8 1.1144 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E19 compound treatment 9.6195794E7 1160000.0 0.1 9.9082136E7 5490000.0 0.48 0.411 0.837 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E20 compound treatment 9.9406181E7 4380000.0 0.38 9.7609799E7 4020000.0 0.35 0.5159 0.9994 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E21 compound treatment 1.03157828E8 8130000.0 0.7 1.01819501E8 8230000.0 0.72 1.0056 0.9999 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E22 compound treatment 1.00611984E8 5580000.0 0.48 1.03202758E8 9610000.0 0.84 0.9357 0.9651 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E23 compound treatment 1.08719234E8 1.37E7 1.18 1.04437424E8 1.08E7 0.95 1.5072 0.9941 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 E24 compound treatment 1.0561395E8 1.06E7 0.91 1.05157941E8 1.16E7 1.01 1.3622 0.9987 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F01 mock treatment 1.08273379E8 1.32E7 1.14 1.03641966E8 1.01E7 0.88 1.4308 0.9916 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F02 mock treatment 1.02104215E8 7070000.0 0.61 1.0083119E8 7240000.0 0.63 0.8801 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F03 compound treatment 1.00671298E8 5640000.0 0.49 9.9517677E7 5930000.0 0.52 0.7113 0.9995 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F04 compound treatment 9.5396065E7 365000.0 0.03 9.5142361E7 1550000.0 0.14 0.1183 0.8487 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F05 compound treatment 9.9698013E7 4670000.0 0.4 9.9181383E7 5590000.0 0.49 0.631 0.9954 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F06 compound treatment 9.3445141E7 -1590000.0 -0.14 9.1776203E7 -1810000.0 -0.16 -0.2092 -0.9973 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F07 compound treatment 7.9857224E7 -1.52E7 -1.31 7.7040441E7 -1.66E7 -1.45 -1.9509 -0.9988 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F08 compound treatment 9.1422277E7 -3610000.0 -0.31 9.1340915E7 -2250000.0 -0.2 -0.3596 -0.9755 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F09 mock treatment 9.5133791E7 103000.0 0.01 9.0954192E7 -2640000.0 -0.23 -0.1569 -0.6794 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F10 mock treatment 8.9791714E7 -5240000.0 -0.45 8.747991E7 -6110000.0 -0.53 -0.6982 -0.9965 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F11 compound treatment 9.0972424E7 -4060000.0 -0.35 9.535781E7 1770000.0 0.15 -0.1385 -0.3615 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F12 compound treatment 7.4184547E7 -2.08E7 -1.8 7.3758909E7 -1.98E7 -1.74 -2.5005 -0.9998 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F13 compound treatment 9.3156625E7 -1870000.0 -0.16 9.6313222E7 2720000.0 0.24 0.054 0.1874 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F14 compound treatment 9.0098136E7 -4930000.0 -0.43 9.1729684E7 -1860000.0 -0.16 -0.4164 -0.913 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F15 compound treatment 7.1848621E7 -2.32E7 -2.0 7.1630684E7 -2.2E7 -1.92 -2.7748 -0.9998 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F16 compound treatment 8.9606306E7 -5420000.0 -0.47 9.0150117E7 -3440000.0 -0.3 -0.5442 -0.9771 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F17 mock treatment 1.03096919E8 8070000.0 0.7 1.00796403E8 7210000.0 0.63 0.9385 0.9988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F18 mock treatment 9.7940307E7 2910000.0 0.25 1.01336968E8 7750000.0 0.68 0.6571 0.9088 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F19 compound treatment 8.577036E7 -9260000.0 -0.8 8.739277E7 -6200000.0 -0.54 -0.9491 -0.9821 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F20 compound treatment 8.6711135E7 -8320000.0 -0.72 8.7565591E7 -6030000.0 -0.53 -0.881 -0.9884 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F21 compound treatment 9.8752271E7 3720000.0 0.32 9.9070192E7 5480000.0 0.48 0.5664 0.9811 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F22 compound treatment 7.2265476E7 -2.28E7 -1.97 7.45365E7 -1.91E7 -1.67 -2.5696 -0.9966 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F23 compound treatment 1.04953814E8 9920000.0 0.86 1.04452792E8 1.09E7 0.95 1.2782 0.9987 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 F24 compound treatment 1.03533869E8 8500000.0 0.73 1.06554994E8 1.3E7 1.13 1.3216 0.9778 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G01 compound treatment 1.1065775E8 1.56E7 1.35 9.6142097E7 2550000.0 0.22 1.1123 0.813 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G02 compound treatment 1.01705318E8 6670000.0 0.58 9.9850396E7 6260000.0 0.55 0.795 0.9997 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G03 mock treatment 1.03407044E8 8380000.0 0.72 9.9835993E7 6250000.0 0.55 0.898 0.9904 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G04 mock treatment 9.5627266E7 596000.0 0.05 9.5207423E7 1620000.0 0.14 0.1365 0.9063 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G05 compound treatment 9.8846965E7 3820000.0 0.33 9.6517578E7 2930000.0 0.26 0.4142 0.9922 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G06 compound treatment 9.4486258E7 -545000.0 -0.05 8.8943284E7 -4650000.0 -0.41 -0.3209 -0.7837 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G07 compound treatment 9.4666363E7 -365000.0 -0.03 9.2845889E7 -745000.0 -0.07 -0.0684 -0.9443 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G08 compound treatment 9.3399357E7 -1630000.0 -0.14 8.7571015E7 -6020000.0 -0.53 -0.4722 -0.8658 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G09 compound treatment 9.2897217E7 -2130000.0 -0.18 8.9397982E7 -4190000.0 -0.37 -0.3898 -0.9493 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G10 compound treatment 8.6843448E7 -8190000.0 -0.71 8.7298514E7 -6290000.0 -0.55 -0.8894 -0.9923 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G11 compound treatment 9.5846453E7 815000.0 0.07 9.2690725E7 -900000.0 -0.08 -0.0059 -0.0558 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G12 compound treatment 9.1894591E7 -3140000.0 -0.27 8.6890756E7 -6700000.0 -0.59 -0.6062 -0.9385 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G13 compound treatment 9.4982586E7 -48500.0 0.0 9.124903E7 -2340000.0 -0.2 -0.1479 -0.7214 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G14 compound treatment 9.3862649E7 -1170000.0 -0.1 9.0869893E7 -2720000.0 -0.24 -0.2397 -0.927 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G15 compound treatment 9.3275045E7 -1760000.0 -0.15 9.0537806E7 -3050000.0 -0.27 -0.2962 -0.964 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G16 compound treatment 9.8433738E7 3400000.0 0.29 9.1509363E7 -2080000.0 -0.18 0.079 0.2285 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G17 compound treatment 9.4147266E7 -884000.0 -0.08 9.4259987E7 669000.0 0.06 -0.0126 -0.1305 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G18 compound treatment 7.6222933E7 -1.88E7 -1.62 7.5092565E7 -1.85E7 -1.62 -2.2934 -1.0 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G19 mock treatment 9.9420642E7 4390000.0 0.38 9.7546445E7 3960000.0 0.35 0.5129 0.999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G20 mock treatment 9.8243538E7 3210000.0 0.28 9.5069583E7 1480000.0 0.13 0.2877 0.9397 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G21 compound treatment 1.01246113E8 6220000.0 0.54 9.731819E7 3730000.0 0.33 0.6103 0.9715 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G22 compound treatment 1.05249003E8 1.02E7 0.88 1.01324675E8 7730000.0 0.68 1.1027 0.9914 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G23 compound treatment 1.07560088E8 1.25E7 1.08 1.03651411E8 1.01E7 0.88 1.3878 0.9948 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 G24 compound treatment 1.07546929E8 1.25E7 1.08 9.2345071E7 -1250000.0 -0.11 0.6873 0.6326 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H01 compound treatment 1.08192156E8 1.32E7 1.14 1.06266182E8 1.27E7 1.11 1.5882 0.9999 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H02 compound treatment 9.8766088E7 3730000.0 0.32 9.1502263E7 -2090000.0 -0.18 0.0989 0.2667 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H03 mock treatment 1.00459036E8 5430000.0 0.47 1.02323035E8 8730000.0 0.76 0.8719 0.9725 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H04 mock treatment 9.5724054E7 693000.0 0.06 9.5130277E7 1540000.0 0.13 0.1376 0.9333 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H05 compound treatment 9.5010296E7 -20800.0 0.0 1.02525158E8 8930000.0 0.78 0.5516 0.7055 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H06 compound treatment 8.3449169E7 -1.16E7 -1.0 7.8628068E7 -1.5E7 -1.31 -1.6333 -0.9912 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H07 compound treatment 9.4291987E7 -739000.0 -0.06 9.3469449E7 -121000.0 -0.01 -0.0526 -0.8135 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H08 compound treatment 9.2823453E7 -2210000.0 -0.19 8.9584724E7 -4010000.0 -0.35 -0.3827 -0.959 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H09 compound treatment 9.3216471E7 -1810000.0 -0.16 9.6627886E7 3040000.0 0.27 0.0771 0.2499 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H10 compound treatment 9.3356968E7 -1670000.0 -0.14 8.8393826E7 -5200000.0 -0.45 -0.4239 -0.8881 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H11 compound treatment 9.7464593E7 2430000.0 0.21 9.2713961E7 -877000.0 -0.08 0.0944 0.4217 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H12 compound treatment 9.0922381E7 -4110000.0 -0.35 9.265031E7 -940000.0 -0.08 -0.3091 -0.8486 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H13 compound treatment 9.6185908E7 1150000.0 0.1 9.6064895E7 2470000.0 0.22 0.2236 0.9381 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H14 compound treatment 9.3023314E7 -2010000.0 -0.17 8.7133226E7 -6460000.0 -0.57 -0.5222 -0.8834 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H15 compound treatment 9.4161522E7 -870000.0 -0.08 9.4844428E7 1250000.0 0.11 0.0245 0.1841 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H16 compound treatment 9.1064463E7 -3970000.0 -0.34 9.1399438E7 -2190000.0 -0.19 -0.3779 -0.9624 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H17 compound treatment 1.00161055E8 5130000.0 0.44 9.8662098E7 5070000.0 0.44 0.6271 1.0 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H18 compound treatment 9.5968128E7 937000.0 0.08 9.6895871E7 3310000.0 0.29 0.2618 0.8715 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H19 mock treatment 1.00872251E8 5840000.0 0.5 1.02130856E8 8540000.0 0.75 0.8852 0.9817 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H20 mock treatment 9.7520997E7 2490000.0 0.22 9.1654282E7 -1940000.0 -0.17 0.0322 0.1177 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H21 compound treatment 1.04262322E8 9230000.0 0.8 9.8682781E7 5090000.0 0.45 0.8789 0.9622 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H22 compound treatment 7.3093665E7 -2.19E7 -1.89 7.5467782E7 -1.81E7 -1.59 -2.4613 -0.9961 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H23 compound treatment 1.10245177E8 1.52E7 1.31 1.03592911E8 1.0E7 0.88 1.5482 0.9805 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 H24 compound treatment 1.05200149E8 1.02E7 0.88 1.05224716E8 1.16E7 1.02 1.341 0.9973 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I01 compound treatment 1.04930176E8 9900000.0 0.86 1.03710469E8 1.01E7 0.89 1.2308 0.9998 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I02 compound treatment 1.01730978E8 6700000.0 0.58 9.9932507E7 6340000.0 0.56 0.8016 0.9998 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I03 compound treatment 9.8735711E7 3700000.0 0.32 9.8724584E7 5130000.0 0.45 0.544 0.9862 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I04 compound treatment 9.6503432E7 1470000.0 0.13 9.8362859E7 4770000.0 0.42 0.3852 0.8824 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I05 mock treatment 9.7979131E7 2950000.0 0.25 9.6074853E7 2480000.0 0.22 0.3338 0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I06 mock treatment 9.5853625E7 823000.0 0.07 9.2545455E7 -1050000.0 -0.09 -0.0144 -0.1247 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I07 compound treatment 8.8752319E7 -6280000.0 -0.54 8.9407773E7 -4180000.0 -0.37 -0.6423 -0.9817 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I08 compound treatment 9.2151063E7 -2880000.0 -0.25 8.9425684E7 -4170000.0 -0.36 -0.4336 -0.9826 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I09 compound treatment 6.7832662E7 -2.72E7 -2.35 6.6748827E7 -2.68E7 -2.35 -3.3222 -1.0 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I10 compound treatment 9.5359205E7 328000.0 0.03 9.4635339E7 1040000.0 0.09 0.0847 0.8848 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I11 compound treatment 9.5087865E7 56800.0 0.0 9.6614457E7 3020000.0 0.26 0.1906 0.7201 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I12 compound treatment 8.9085446E7 -5950000.0 -0.51 9.1160535E7 -2430000.0 -0.21 -0.5135 -0.9239 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I13 compound treatment 9.2489134E7 -2540000.0 -0.22 9.5025058E7 1430000.0 0.13 -0.0665 -0.2629 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I14 compound treatment 8.9706895E7 -5320000.0 -0.46 9.5757157E7 2170000.0 0.19 -0.1911 -0.3842 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I15 compound treatment 9.712813E7 2100000.0 0.18 9.7379209E7 3790000.0 0.33 0.3625 0.9595 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I16 compound treatment 9.140326E7 -3630000.0 -0.31 9.408409E7 493000.0 0.04 -0.191 -0.604 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I17 compound treatment 9.9340376E7 4310000.0 0.37 9.7867343E7 4280000.0 0.37 0.5278 1.0 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I18 compound treatment 9.4851861E7 -179000.0 -0.02 9.4601819E7 1010000.0 0.09 0.0516 0.5747 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I19 compound treatment 9.3848638E7 -1180000.0 -0.1 9.3951598E7 361000.0 0.03 -0.0499 -0.4666 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I20 compound treatment 9.771035E7 2680000.0 0.23 9.9014437E7 5420000.0 0.47 0.4993 0.9455 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I21 mock treatment 9.5889235E7 858000.0 0.07 8.0868558E7 -1.27E7 -1.11 -0.7349 -0.6586 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I22 mock treatment 9.78886E7 2860000.0 0.25 9.5279605E7 1690000.0 0.15 0.279 0.9699 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I23 compound treatment 1.06692492E8 1.17E7 1.01 1.03868665E8 1.03E7 0.9 1.3483 0.9984 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 I24 compound treatment 1.0755711E8 1.25E7 1.08 1.05280458E8 1.17E7 1.02 1.4884 0.9996 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J01 compound treatment 1.12682847E8 1.77E7 1.52 1.07414488E8 1.38E7 1.21 1.9335 0.9934 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J02 compound treatment 1.00403893E8 5370000.0 0.46 9.9358228E7 5770000.0 0.5 0.6851 0.9991 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J03 compound treatment 1.00699744E8 5670000.0 0.49 1.03794875E8 1.02E7 0.89 0.9777 0.96 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J04 compound treatment 9.3382151E7 -1650000.0 -0.14 9.4066194E7 475000.0 0.04 -0.0713 -0.4804 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J05 mock treatment 9.6375257E7 1340000.0 0.12 9.6153222E7 2560000.0 0.22 0.2407 0.953 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J06 mock treatment 8.8310257E7 -6720000.0 -0.58 9.1508501E7 -2080000.0 -0.18 -0.5393 -0.8864 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J07 compound treatment 9.6308777E7 1280000.0 0.11 9.6090799E7 2500000.0 0.22 0.2328 0.9498 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J08 compound treatment 7.0864743E7 -2.42E7 -2.09 7.2324296E7 -2.13E7 -1.86 -2.792 -0.9984 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J09 compound treatment 6.0162271E7 -3.49E7 -3.01 6.0167573E7 -3.34E7 -2.93 -4.198 -0.9999 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J10 compound treatment 8.5219858E7 -9810000.0 -0.85 8.95204E7 -4070000.0 -0.36 -0.8511 -0.9259 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J11 compound treatment 8.7138E7 -7890000.0 -0.68 9.2187601E7 -1400000.0 -0.12 -0.5689 -0.8213 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J12 compound treatment 8.976213E7 -5270000.0 -0.46 9.1609815E7 -1980000.0 -0.17 -0.4444 -0.9125 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J13 compound treatment 2.0202659E7 -7.48E7 -6.46 2.0318848E7 -7.33E7 -6.41 -9.1045 -1.0 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J14 compound treatment 9.0923895E7 -4110000.0 -0.35 9.3302786E7 -288000.0 -0.03 -0.2687 -0.7554 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J15 compound treatment 9.5994035E7 963000.0 0.08 9.6970937E7 3380000.0 0.3 0.268 0.8721 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J16 compound treatment 6.8306412E7 -2.67E7 -2.31 7.2445502E7 -2.11E7 -1.85 -2.9408 -0.994 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J17 compound treatment 6.8143008E7 -2.69E7 -2.32 6.8853466E7 -2.47E7 -2.16 -3.173 -0.9994 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J18 compound treatment 9.3466613E7 -1560000.0 -0.14 9.5467671E7 1880000.0 0.16 0.0206 0.0969 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J19 compound treatment 9.4335474E7 -696000.0 -0.06 9.8449698E7 4860000.0 0.43 0.2582 0.6012 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J20 compound treatment 9.5547285E7 516000.0 0.04 9.6245E7 2650000.0 0.23 0.1958 0.8277 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J21 mock treatment 1.02028356E8 7000000.0 0.6 8.7116077E7 -6470000.0 -0.57 0.0267 0.0322 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J22 mock treatment 9.5961763E7 931000.0 0.08 9.5870849E7 2280000.0 0.2 0.1979 0.9201 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J23 compound treatment 1.05173967E8 1.01E7 0.88 1.07921154E8 1.43E7 1.25 1.5063 0.9846 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 J24 compound treatment 1.01071835E8 6040000.0 0.52 1.04109546E8 1.05E7 0.92 1.0199 0.9638 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K01 compound treatment 7.7147507E7 -1.79E7 -1.54 7.5262159E7 -1.83E7 -1.6 -2.2265 -0.9998 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K02 compound treatment 1.00394709E8 5360000.0 0.46 9.6081645E7 2490000.0 0.22 0.4817 0.9409 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K03 compound treatment 9.3283476E7 -1750000.0 -0.15 9.2320975E7 -1270000.0 -0.11 -0.1853 -0.9887 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K04 compound treatment 8.7487338E7 -7540000.0 -0.65 8.7955803E7 -5630000.0 -0.49 -0.8094 -0.9906 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K05 compound treatment 9.8624821E7 3590000.0 0.31 1.02151912E8 8560000.0 0.75 0.7493 0.9239 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K06 compound treatment 8.7200715E7 -7830000.0 -0.68 8.6910686E7 -6680000.0 -0.58 -0.8916 -0.9974 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K07 mock treatment 9.5356041E7 325000.0 0.03 9.7013844E7 3420000.0 0.3 0.2317 0.77 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K08 mock treatment 8.8309313E7 -6720000.0 -0.58 8.6628821E7 -6960000.0 -0.61 -0.8414 -0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K09 compound treatment 8.9906481E7 -5120000.0 -0.44 9.4583617E7 993000.0 0.09 -0.2515 -0.5576 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K10 compound treatment 8.915E7 -5880000.0 -0.51 9.1741044E7 -1850000.0 -0.16 -0.4736 -0.8884 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K11 compound treatment 8.2009574E7 -1.3E7 -1.12 8.5918982E7 -7670000.0 -0.67 -1.27 -0.9696 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K12 compound treatment 4.540433E7 -4.96E7 -4.29 4.7194004E7 -4.64E7 -4.06 -5.9022 -0.9996 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K13 compound treatment 9.679652E7 1770000.0 0.15 8.341117E7 -1.02E7 -0.89 -0.5221 -0.5777 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K14 compound treatment 8.3044313E7 -1.2E7 -1.04 8.7287235E7 -6300000.0 -0.55 -1.1222 -0.9566 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K15 mock treatment 9.4787331E7 -244000.0 -0.02 9.5757819E7 2170000.0 0.19 0.1192 0.6248 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K16 mock treatment 9.3936256E7 -1090000.0 -0.09 8.7751685E7 -5840000.0 -0.51 -0.4282 -0.824 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K17 compound treatment 7.5221818E7 -1.98E7 -1.71 7.8637091E7 -1.5E7 -1.31 -2.1352 -0.9912 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K18 compound treatment 2.0740782E7 -7.43E7 -6.42 2.0292576E7 -7.33E7 -6.41 -9.0732 -1.0 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K19 compound treatment 9.6770341E7 1740000.0 0.15 9.8383442E7 4790000.0 0.42 0.4028 0.9041 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K20 compound treatment 9.8368531E7 3340000.0 0.29 9.6017891E7 2430000.0 0.21 0.354 0.9887 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K21 compound treatment 1.04137686E8 9110000.0 0.79 1.03507484E8 9920000.0 0.87 1.1699 0.9988 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K22 compound treatment 1.02498824E8 7470000.0 0.65 9.9788146E7 6200000.0 0.54 0.8396 0.9963 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K23 mock treatment 1.04336076E8 9300000.0 0.8 7.8585444E7 -1.5E7 -1.31 -0.3603 -0.234 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 K24 mock treatment 9.969247E7 4660000.0 0.4 1.01116236E8 7530000.0 0.66 0.7504 0.9721 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L01 compound treatment 1.04905346E8 9870000.0 0.85 1.03501207E8 9910000.0 0.87 1.2164 1.0 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L02 compound treatment 9.3152414E7 -1880000.0 -0.16 8.7968211E7 -5620000.0 -0.49 -0.4627 -0.893 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L03 compound treatment 8.5787893E7 -9240000.0 -0.8 1.03314295E8 9720000.0 0.85 0.0372 0.0319 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L04 compound treatment 8.7709974E7 -7320000.0 -0.63 9.6800617E7 3210000.0 0.28 -0.2485 -0.3591 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L05 compound treatment 9.6417246E7 1390000.0 0.12 9.9892786E7 6300000.0 0.55 0.4747 0.841 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L06 compound treatment 9.2373151E7 -2660000.0 -0.23 9.5141871E7 1550000.0 0.14 -0.0663 -0.2487 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L07 mock treatment 9.5608737E7 578000.0 0.05 9.4886094E7 1300000.0 0.11 0.1154 0.932 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L08 mock treatment 8.8443622E7 -6590000.0 -0.57 9.377594E7 185000.0 0.02 -0.3909 -0.6867 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L09 compound treatment 2.3118807E7 -7.19E7 -6.21 2.0489095E7 -7.31E7 -6.4 -8.9158 -0.9999 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L10 compound treatment 8.3026041E7 -1.2E7 -1.04 8.8393844E7 -5200000.0 -0.45 -1.0548 -0.9316 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L11 compound treatment 9.2645726E7 -2390000.0 -0.21 9.5632496E7 2040000.0 0.18 -0.0193 -0.0709 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L12 compound treatment 7.0710601E7 -2.43E7 -2.1 7.6152881E7 -1.74E7 -1.53 -2.5645 -0.9877 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L13 compound treatment 9.3301561E7 -1730000.0 -0.15 9.5511674E7 1920000.0 0.17 0.0132 0.0589 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L14 compound treatment 8.402579E7 -1.1E7 -0.95 9.3442385E7 -148000.0 -0.01 -0.6813 -0.7167 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L15 mock treatment 9.3073011E7 -1960000.0 -0.17 9.2348828E7 -1240000.0 -0.11 -0.1964 -0.9771 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L16 mock treatment 8.939362E7 -5640000.0 -0.49 9.6275521E7 2680000.0 0.23 -0.1782 -0.3295 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L17 compound treatment 9.7603373E7 2570000.0 0.22 9.3029388E7 -561000.0 -0.05 0.1224 0.5378 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L18 compound treatment 8.1532016E7 -1.35E7 -1.17 8.0626492E7 -1.3E7 -1.13 -1.6267 -0.9999 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L19 compound treatment 9.9398652E7 4370000.0 0.38 1.02785976E8 9200000.0 0.8 0.8358 0.9404 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L20 compound treatment 9.8562422E7 3530000.0 0.31 9.8423081E7 4830000.0 0.42 0.5147 0.9871 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L21 compound treatment 9.7187064E7 2160000.0 0.19 1.04727686E8 1.11E7 0.97 0.8209 0.8272 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L22 compound treatment 1.00391411E8 5360000.0 0.46 9.9278178E7 5690000.0 0.5 0.6793 0.9993 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L23 mock treatment 1.01366096E8 6340000.0 0.55 9.2389651E7 -1200000.0 -0.11 0.3126 0.561 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 L24 mock treatment 1.05287986E8 1.03E7 0.89 1.04524981E8 1.09E7 0.96 1.3031 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M01 compound treatment 1.11370125E8 1.63E7 1.41 9.7273489E7 3680000.0 0.32 1.2258 0.8468 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M02 compound treatment 9.48314E7 -200000.0 -0.02 9.6889435E7 3300000.0 0.29 0.1919 0.6637 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M03 compound treatment 1.02377166E8 7350000.0 0.63 1.05120477E8 1.15E7 1.01 1.1622 0.975 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M04 compound treatment 1.00787624E8 5760000.0 0.5 9.0909833E7 -2680000.0 -0.23 0.1857 0.3377 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M05 compound treatment 4.4683348E7 -5.03E7 -4.35 2.1641128E7 -7.19E7 -6.3 -7.5275 -0.9837 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M06 compound treatment 9.8302881E7 3270000.0 0.28 9.88459E7 5260000.0 0.46 0.525 0.9726 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M07 compound treatment 9.8256731E7 3230000.0 0.28 9.813879E7 4550000.0 0.4 0.4785 0.9848 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M08 compound treatment 8.5369104E7 -9660000.0 -0.83 8.3526047E7 -1.01E7 -0.88 -1.2129 -0.9996 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M09 mock treatment 9.1460447E7 -3570000.0 -0.31 8.0005575E7 -1.36E7 -1.19 -1.0588 -0.862 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M10 mock treatment 8.9265034E7 -5770000.0 -0.5 7.4557801E7 -1.9E7 -1.67 -1.53 -0.88 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M11 compound treatment 6.4885283E7 -3.01E7 -2.6 6.7273567E7 -2.63E7 -2.3 -3.4698 -0.9981 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M12 compound treatment 3.2703345E7 -6.23E7 -5.38 2.2002039E7 -7.16E7 -6.27 -8.2368 -0.9971 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M13 mock treatment 9.1701862E7 -3330000.0 -0.29 9.4271736E7 681000.0 0.06 -0.1612 -0.5489 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M14 mock treatment 8.0993035E7 -1.4E7 -1.21 8.1742638E7 -1.18E7 -1.04 -1.5906 -0.997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M15 compound treatment 9.6624285E7 1590000.0 0.14 7.9652739E7 -1.39E7 -1.22 -0.7652 -0.6234 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M16 compound treatment 8.3241463E7 -1.18E7 -1.02 8.3965546E7 -9630000.0 -0.84 -1.3157 -0.9956 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M17 compound treatment 9.4464678E7 -566000.0 -0.05 7.4583943E7 -1.9E7 -1.66 -1.2108 -0.7276 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M18 compound treatment 9.7065843E7 2030000.0 0.18 9.3030965E7 -560000.0 -0.05 0.0896 0.4913 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M19 compound treatment 9.6754549E7 1720000.0 0.15 1.00562076E8 6970000.0 0.61 0.5367 0.8546 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M20 compound treatment 9.6476249E7 1450000.0 0.12 9.1349998E7 -2240000.0 -0.2 -0.0504 -0.2168 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M21 compound treatment 9.9490055E7 4460000.0 0.39 8.4831235E7 -8760000.0 -0.77 -0.2697 -0.3144 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M22 compound treatment 1.05397427E8 1.04E7 0.9 9.0307075E7 -3280000.0 -0.29 0.4299 0.4572 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M23 compound treatment 9.6608889E7 1580000.0 0.14 1.04048672E8 1.05E7 0.92 0.7435 0.8035 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 M24 compound treatment 1.08030943E8 1.3E7 1.12 1.06567753E8 1.3E7 1.14 1.597 1.0 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N01 compound treatment 1.08960253E8 1.39E7 1.2 1.04317698E8 1.07E7 0.94 1.5145 0.9925 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N02 compound treatment 1.01122155E8 6090000.0 0.53 9.9808356E7 6220000.0 0.54 0.7568 0.9999 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N03 compound treatment 1.09928019E8 1.49E7 1.29 9.7700284E7 4110000.0 0.36 1.1641 0.8714 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N04 compound treatment 8.6534575E7 -8500000.0 -0.73 9.153299E7 -2060000.0 -0.18 -0.6463 -0.8553 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N05 compound treatment 9.5835603E7 805000.0 0.07 1.01704245E8 8110000.0 0.71 0.5512 0.7726 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N06 compound treatment 6.6439188E7 -2.86E7 -2.47 6.1618028E7 -3.2E7 -2.8 -3.7248 -0.9981 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N07 compound treatment 8.9669756E7 -5360000.0 -0.46 1.01889151E8 8300000.0 0.73 0.1861 0.2161 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N08 compound treatment 9.7056803E7 2030000.0 0.17 9.6000936E7 2410000.0 0.21 0.2729 0.9957 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N09 mock treatment 8.6354173E7 -8680000.0 -0.75 6.8960972E7 -2.46E7 -2.16 -2.0541 -0.9001 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N10 mock treatment 8.4311051E7 -1.07E7 -0.93 7.2937591E7 -2.07E7 -1.81 -1.9328 -0.9517 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N11 compound treatment 9.0465038E7 -4570000.0 -0.39 9.3351364E7 -239000.0 -0.02 -0.2937 -0.7436 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N12 compound treatment 6.4096971E7 -3.09E7 -2.67 6.7867609E7 -2.57E7 -2.25 -3.4811 -0.9964 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N13 mock treatment 9.251426E7 -2520000.0 -0.22 9.4747022E7 1160000.0 0.1 -0.0822 -0.3426 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N14 mock treatment 8.7699975E7 -7330000.0 -0.63 9.1386638E7 -2200000.0 -0.19 -0.5841 -0.8825 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N15 compound treatment 3.1521961E7 -6.35E7 -5.49 4.5056909E7 -4.85E7 -4.25 -6.8823 -0.992 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N16 compound treatment 8.1769812E7 -1.33E7 -1.15 8.6039711E7 -7550000.0 -0.66 -1.2772 -0.9658 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N17 compound treatment 9.9154947E7 4120000.0 0.36 8.4756243E7 -8830000.0 -0.77 -0.2949 -0.3464 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N18 compound treatment 8.6793583E7 -8240000.0 -0.71 8.9574964E7 -4020000.0 -0.35 -0.7516 -0.9471 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N19 compound treatment 1.0496033E8 9930000.0 0.86 1.03137607E8 9550000.0 0.84 1.1972 0.9999 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N20 compound treatment 9.3199689E7 -1830000.0 -0.16 9.9384093E7 5790000.0 0.51 0.2467 0.4644 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N21 compound treatment 9.5412006E7 381000.0 0.03 7.8982753E7 -1.46E7 -1.28 -0.8807 -0.6887 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N22 compound treatment 1.0127209E8 6240000.0 0.54 9.2368557E7 -1220000.0 -0.11 0.3055 0.556 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N23 compound treatment 9.7070013E7 2040000.0 0.18 9.9593088E7 6000000.0 0.53 0.496 0.8952 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 N24 compound treatment 1.04232544E8 9200000.0 0.79 9.560138E7 2010000.0 0.18 0.6864 0.8432 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O01 compound treatment 1.07829318E8 1.28E7 1.11 9.6393586E7 2800000.0 0.25 0.9551 0.8435 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O02 compound treatment 8.3141707E7 -1.19E7 -1.03 7.9093958E7 -1.45E7 -1.27 -1.6233 -0.9945 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O03 compound treatment 8.4156134E7 -1.09E7 -0.94 8.577902E7 -7810000.0 -0.68 -1.1476 -0.9878 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O04 compound treatment 9.8174224E7 3140000.0 0.27 8.2994507E7 -1.06E7 -0.93 -0.4638 -0.48 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O05 compound treatment 1.03834232E8 8800000.0 0.76 9.9197299E7 5610000.0 0.49 0.8846 0.9775 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O06 compound treatment 9.4683547E7 -348000.0 -0.03 9.5512616E7 1920000.0 0.17 0.0977 0.5719 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O07 compound treatment 9.0297905E7 -4730000.0 -0.41 8.9281202E7 -4310000.0 -0.38 -0.5558 -0.9992 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O08 compound treatment 9.4641057E7 -390000.0 -0.03 9.1088398E7 -2500000.0 -0.22 -0.1787 -0.8064 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O09 compound treatment 9.4298585E7 -733000.0 -0.06 9.3471327E7 -119000.0 -0.01 -0.0521 -0.8129 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O10 compound treatment 8.8184525E7 -6850000.0 -0.59 8.837751E7 -5210000.0 -0.46 -0.7408 -0.9918 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O11 mock treatment 9.1242187E7 -3790000.0 -0.33 9.2990581E7 -600000.0 -0.05 -0.2685 -0.8102 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O12 mock treatment 8.2119314E7 -1.29E7 -1.12 8.6146105E7 -7440000.0 -0.65 -1.2493 -0.9672 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O13 compound treatment 9.7055735E7 2020000.0 0.17 8.3991554E7 -9600000.0 -0.84 -0.4704 -0.5482 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O14 compound treatment 9.0041674E7 -4990000.0 -0.43 9.1524232E7 -2070000.0 -0.18 -0.4326 -0.9256 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O15 compound treatment 6.5932092E7 -2.91E7 -2.51 6.3410863E7 -3.02E7 -2.64 -3.6449 -0.9997 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O16 compound treatment 8.8181227E7 -6850000.0 -0.59 9.1165002E7 -2430000.0 -0.21 -0.5685 -0.9044 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O17 compound treatment 9.9423577E7 4390000.0 0.38 9.6356513E7 2770000.0 0.24 0.4394 0.9764 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O18 compound treatment 9.3249002E7 -1780000.0 -0.15 9.5764959E7 2170000.0 0.19 0.0257 0.1051 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O19 compound treatment 9.9056044E7 4020000.0 0.35 1.01906375E8 8320000.0 0.73 0.7604 0.9428 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O20 compound treatment 1.0184853E8 6820000.0 0.59 9.7454252E7 3860000.0 0.34 0.6555 0.9653 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O21 compound treatment 1.0101839E8 5990000.0 0.52 1.02479967E8 8890000.0 0.78 0.9158 0.9803 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O22 compound treatment 1.01789539E8 6760000.0 0.58 1.01382825E8 7790000.0 0.68 0.895 0.997 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O23 compound treatment 1.07935437E8 1.29E7 1.11 1.05093248E8 1.15E7 1.01 1.5 0.9987 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 O24 compound treatment 1.09047046E8 1.4E7 1.21 1.01307897E8 7720000.0 0.68 1.3336 0.962 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P01 compound treatment 8.3951502E7 -1.11E7 -0.96 8.7706964E7 -5880000.0 -0.51 -1.0408 -0.9577 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P02 compound treatment 9.8153071E7 3120000.0 0.27 9.6319443E7 2730000.0 0.24 0.3595 0.9982 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P03 compound treatment 7.160181E7 -2.34E7 -2.02 7.297994E7 -2.06E7 -1.8 -2.7064 -0.9984 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P04 compound treatment 9.5100767E7 69700.0 0.01 8.0718101E7 -1.29E7 -1.13 -0.7924 -0.7033 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P05 compound treatment 3.766774E7 -5.74E7 -4.95 3.3602577E7 -6.0E7 -5.25 -7.2158 -0.9996 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P06 compound treatment 9.5435862E7 405000.0 0.03 9.4852826E7 1260000.0 0.11 0.1028 0.8875 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P07 compound treatment 9.8253749E7 3220000.0 0.28 9.580366E7 2210000.0 0.19 0.3338 0.9843 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P08 compound treatment 9.2300504E7 -2730000.0 -0.24 8.9831116E7 -3760000.0 -0.33 -0.3994 -0.9867 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P09 compound treatment 9.4985307E7 -45800.0 0.0 9.1004763E7 -2590000.0 -0.23 -0.1628 -0.7194 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P10 compound treatment 9.3118755E7 -1910000.0 -0.17 8.8577904E7 -5010000.0 -0.44 -0.427 -0.9109 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P11 mock treatment 9.4366684E7 -664000.0 -0.06 8.9899446E7 -3690000.0 -0.32 -0.269 -0.8199 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P12 mock treatment 9.0832033E7 -4200000.0 -0.36 8.9515911E7 -4070000.0 -0.36 -0.5086 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P13 compound treatment 9.502528E7 -5810.0 0.0 7.7893539E7 -1.57E7 -1.37 -0.9718 -0.7074 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P14 compound treatment 8.9343285E7 -5690000.0 -0.49 8.4434431E7 -9160000.0 -0.8 -0.914 -0.9724 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P15 compound treatment 1.0426714E8 9240000.0 0.8 9.7113007E7 3520000.0 0.31 0.7821 0.9144 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P16 compound treatment 8.7200903E7 -7830000.0 -0.68 9.0855029E7 -2740000.0 -0.24 -0.6475 -0.9025 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P17 compound treatment 1.03829058E8 8800000.0 0.76 9.9223082E7 5630000.0 0.49 0.8859 0.978 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P18 compound treatment 9.5026092E7 -5000.0 0.0 9.3825395E7 235000.0 0.02 0.0142 0.6921 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P19 compound treatment 7.8812064E7 -1.62E7 -1.4 7.5992193E7 -1.76E7 -1.54 -2.0796 -0.9989 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P20 compound treatment 7.3719557E7 -2.13E7 -1.84 7.2381696E7 -2.12E7 -1.86 -2.6141 -1.0 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P21 compound treatment 8.0577275E7 -1.45E7 -1.25 8.0971302E7 -1.26E7 -1.1 -1.6637 -0.9981 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P22 compound treatment 7.7116745E7 -1.79E7 -1.55 7.4284073E7 -1.93E7 -1.69 -2.2889 -0.999 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P23 compound treatment 9.5052793E7 21700.0 0.0 9.256609E7 -1020000.0 -0.09 -0.0621 -0.6922 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2095 P24 compound treatment 8.4365624E7 -1.07E7 -0.92 7.7046842E7 -1.65E7 -1.45 -1.6752 -0.9762 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A01 compound treatment 9.3310708E7 -4090000.0 -0.35 9.7895649E7 3560000.0 0.31 -0.0298 -0.0633 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A02 compound treatment 1.0564324E8 8240000.0 0.71 1.03082051E8 8740000.0 0.77 1.0444 0.9993 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A03 compound treatment 7.502534E7 -2.24E7 -1.93 7.9488637E7 -1.48E7 -1.3 -2.2857 -0.9813 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A04 compound treatment 1.04759314E8 7350000.0 0.64 9.2016267E7 -2320000.0 -0.2 0.3056 0.4582 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A05 compound treatment 9.3675677E7 -3730000.0 -0.32 1.02972343E8 8640000.0 0.76 0.3067 0.3733 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A06 compound treatment 8.147418E7 -1.59E7 -1.38 7.9961621E7 -1.44E7 -1.26 -1.8625 -0.999 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A07 compound treatment 7.5639834E7 -2.18E7 -1.88 7.7873485E7 -1.65E7 -1.44 -2.3481 -0.9914 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A08 compound treatment 9.027501E7 -7130000.0 -0.62 8.3186683E7 -1.12E7 -0.98 -1.1255 -0.9754 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A09 compound treatment 9.3244939E7 -4160000.0 -0.36 1.01468379E8 7130000.0 0.62 0.1873 0.2601 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A10 compound treatment 1.0149997E8 4100000.0 0.35 9.595842E7 1620000.0 0.14 0.3505 0.9195 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A11 compound treatment 1.01742713E8 4340000.0 0.37 9.8880256E7 4540000.0 0.4 0.5461 0.9996 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A12 compound treatment 9.6420918E7 -983000.0 -0.08 9.3812382E7 -525000.0 -0.05 -0.0925 -0.9583 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A13 mock treatment 8.9871479E7 -7530000.0 -0.65 9.9452814E7 5120000.0 0.45 -0.1435 -0.1817 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A14 mock treatment 9.6565032E7 -839000.0 -0.07 9.3714624E7 -623000.0 -0.05 -0.0898 -0.9901 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A15 compound treatment 1.01107347E8 3700000.0 0.32 9.8436789E7 4100000.0 0.36 0.4799 0.9984 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A16 compound treatment 7.5300243E7 -2.21E7 -1.91 7.5080291E7 -1.93E7 -1.69 -2.5417 -0.9981 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A17 compound treatment 9.315616E7 -4250000.0 -0.37 1.00359813E8 6020000.0 0.53 0.1133 0.1763 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A18 compound treatment 7.3585687E7 -2.38E7 -2.06 7.0799042E7 -2.35E7 -2.06 -2.9114 -1.0 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A19 compound treatment 1.05296638E8 7890000.0 0.68 1.01180886E8 6840000.0 0.6 0.9055 0.9979 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A20 compound treatment 9.8167282E7 763000.0 0.07 1.01426669E8 7090000.0 0.62 0.4853 0.7778 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A21 compound treatment 9.6723734E7 -681000.0 -0.06 9.9677455E7 5340000.0 0.47 0.2889 0.6133 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A22 compound treatment 1.07819753E8 1.04E7 0.9 1.02908589E8 8570000.0 0.75 1.1666 0.9959 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A23 compound treatment 1.06923544E8 9520000.0 0.82 1.03134676E8 8800000.0 0.77 1.1258 0.9995 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 A24 compound treatment 1.0702058E8 9620000.0 0.83 1.02867856E8 8530000.0 0.75 1.1152 0.9986 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B01 compound treatment 1.08993748E8 1.16E7 1.0 1.03282919E8 8950000.0 0.78 1.2614 0.9926 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B02 compound treatment 1.00327565E8 2920000.0 0.25 9.9511361E7 5170000.0 0.45 0.4987 0.9619 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B03 compound treatment 1.06157418E8 8750000.0 0.76 1.01587641E8 7250000.0 0.63 0.9833 0.9962 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B04 compound treatment 8.6749687E7 -1.07E7 -0.92 8.3420784E7 -1.09E7 -0.96 -1.3263 -0.9998 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B05 compound treatment 9.7964288E7 560000.0 0.05 9.8627924E7 4290000.0 0.38 0.2997 0.7916 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B06 compound treatment 9.9394085E7 1990000.0 0.17 9.6278137E7 1940000.0 0.17 0.2416 1.0 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B07 compound treatment 1.00601151E8 3200000.0 0.28 9.826598E7 3930000.0 0.34 0.4384 0.9941 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B08 compound treatment 8.5085252E7 -1.23E7 -1.06 8.5577602E7 -8760000.0 -0.77 -1.2945 -0.9871 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B09 compound treatment 9.7459249E7 54900.0 0.0 9.6790752E7 2450000.0 0.21 0.1552 0.7225 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B10 compound treatment 9.4725707E7 -2680000.0 -0.23 9.2856843E7 -1480000.0 -0.13 -0.2552 -0.9624 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B11 compound treatment 1.00225959E8 2820000.0 0.24 9.9044523E7 4710000.0 0.41 0.4636 0.9686 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B12 compound treatment 7.8007569E7 -1.94E7 -1.68 7.7720362E7 -1.66E7 -1.45 -2.213 -0.9975 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B13 mock treatment 9.7550921E7 147000.0 0.01 9.6330889E7 1990000.0 0.17 0.1323 0.7564 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B14 mock treatment 9.4818593E7 -2590000.0 -0.22 9.02678E7 -4070000.0 -0.36 -0.4098 -0.9747 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B15 compound treatment 1.01003106E8 3600000.0 0.31 9.8976995E7 4640000.0 0.41 0.5069 0.9913 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B16 compound treatment 8.4261654E7 -1.31E7 -1.14 8.4315158E7 -1.0E7 -0.88 -1.4229 -0.9919 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B17 compound treatment 1.03406868E8 6000000.0 0.52 1.01273737E8 6940000.0 0.61 0.7959 0.9969 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B18 compound treatment 6.4794093E7 -3.26E7 -2.82 6.7868681E7 -2.65E7 -2.32 -3.6296 -0.9953 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B19 compound treatment 1.03366364E8 5960000.0 0.51 1.02954029E8 8620000.0 0.75 0.8974 0.9827 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B20 compound treatment 8.3256343E7 -1.41E7 -1.22 8.7853645E7 -6480000.0 -0.57 -1.2653 -0.9391 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B21 compound treatment 1.03099831E8 5700000.0 0.49 1.03075126E8 8740000.0 0.76 0.8886 0.9772 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B22 compound treatment 9.7571962E7 168000.0 0.01 9.896501E7 4630000.0 0.41 0.2966 0.7319 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B23 compound treatment 1.1328474E8 1.59E7 1.37 1.03283177E8 8950000.0 0.78 1.5235 0.9646 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 B24 compound treatment 1.02589438E8 5190000.0 0.45 9.2011546E7 -2330000.0 -0.2 0.1728 0.3512 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C01 compound treatment 1.0630063E8 8900000.0 0.77 9.9203141E7 4870000.0 0.43 0.8445 0.9612 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C02 compound treatment 1.04631365E8 7230000.0 0.62 1.0083088E8 6490000.0 0.57 0.8432 0.9989 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C03 compound treatment 1.05465362E8 8060000.0 0.7 9.4774018E7 437000.0 0.04 0.5194 0.7448 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C04 compound treatment 6.6559685E7 -3.08E7 -2.66 7.5800334E7 -1.85E7 -1.62 -3.031 -0.9717 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C05 compound treatment 7.2152614E7 -2.53E7 -2.18 7.5483154E7 -1.89E7 -1.65 -2.709 -0.9905 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C06 compound treatment 1.02368946E8 4960000.0 0.43 9.7432799E7 3100000.0 0.27 0.4948 0.9755 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C07 compound treatment 8.5833454E7 -1.16E7 -1.0 7.8557509E7 -1.58E7 -1.38 -1.6832 -0.9874 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C08 compound treatment 8.924297E7 -8160000.0 -0.7 9.7083765E7 2750000.0 0.24 -0.3285 -0.441 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C09 compound treatment 9.7182533E7 -222000.0 -0.02 9.577601E7 1440000.0 0.13 0.0755 0.5927 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C10 compound treatment 9.5912499E7 -1490000.0 -0.13 8.5203067E7 -9130000.0 -0.8 -0.6564 -0.8106 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C11 mock treatment 9.7045618E7 -359000.0 -0.03 9.7403767E7 3070000.0 0.27 0.1679 0.6213 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C12 mock treatment 8.6934906E7 -1.05E7 -0.9 9.3347823E7 -989000.0 -0.09 -0.7006 -0.7713 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C13 compound treatment 9.8623E7 1220000.0 0.11 9.6243879E7 1910000.0 0.17 0.1924 0.9753 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C14 compound treatment 9.5245176E7 -2160000.0 -0.19 8.7018477E7 -7320000.0 -0.64 -0.5848 -0.8766 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C15 mock treatment 9.5908344E7 -1500000.0 -0.13 9.7033208E7 2700000.0 0.24 0.0755 0.2806 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C16 mock treatment 8.8029851E7 -9370000.0 -0.81 9.4240987E7 -96200.0 -0.01 -0.5785 -0.7144 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C17 compound treatment 9.6381996E7 -1020000.0 -0.09 9.3607086E7 -730000.0 -0.06 -0.1076 -0.9874 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C18 compound treatment 1.01763974E8 4360000.0 0.38 9.1524549E7 -2810000.0 -0.25 0.0922 0.205 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C19 compound treatment 1.00005038E8 2600000.0 0.22 1.02856397E8 8520000.0 0.75 0.686 0.881 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C20 compound treatment 9.3493265E7 -3910000.0 -0.34 1.0130653E8 6970000.0 0.61 0.1924 0.276 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C21 compound treatment 1.10247564E8 1.28E7 1.11 9.9297447E7 4960000.0 0.43 1.0914 0.9162 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C22 compound treatment 1.06961636E8 9560000.0 0.83 1.02229199E8 7890000.0 0.69 1.0721 0.9961 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C23 compound treatment 7.7951859E7 -1.95E7 -1.68 8.1075645E7 -1.33E7 -1.16 -2.0087 -0.9837 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 C24 compound treatment 1.03459293E8 6050000.0 0.52 1.02643038E8 8310000.0 0.73 0.8838 0.9869 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D01 compound treatment 1.0100985E8 3610000.0 0.31 9.4317267E7 -19900.0 0.0 0.219 0.7031 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D02 compound treatment 9.6203237E7 -1200000.0 -0.1 9.1722659E7 -2610000.0 -0.23 -0.2352 -0.936 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D03 compound treatment 1.02666757E8 5260000.0 0.45 1.01105449E8 6770000.0 0.59 0.7402 0.9914 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D04 compound treatment 6.0785559E7 -3.66E7 -3.16 6.3111122E7 -3.12E7 -2.73 -4.1689 -0.9974 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D05 compound treatment 9.2978105E7 -4430000.0 -0.38 9.0314427E7 -4020000.0 -0.35 -0.5193 -0.9992 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D06 compound treatment 9.837059E7 966000.0 0.08 9.5007584E7 670000.0 0.06 0.1005 0.9851 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D07 compound treatment 1.06256399E8 8850000.0 0.76 1.00448635E8 6110000.0 0.53 0.9188 0.9847 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D08 compound treatment 8.5516227E7 -1.19E7 -1.03 9.0245539E7 -4090000.0 -0.36 -0.9793 -0.9005 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D09 compound treatment 8.2860605E7 -1.45E7 -1.26 7.5417808E7 -1.89E7 -1.66 -2.0591 -0.9907 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D10 compound treatment 9.1817763E7 -5590000.0 -0.48 8.929774E7 -5040000.0 -0.44 -0.6531 -0.999 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D11 mock treatment 9.7358084E7 -46200.0 0.0 9.6480759E7 2140000.0 0.19 0.1298 0.6919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D12 mock treatment 9.3982457E7 -3420000.0 -0.3 9.1648088E7 -2690000.0 -0.24 -0.3754 -0.9936 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D13 compound treatment 9.3605699E7 -3800000.0 -0.33 9.2634225E7 -1700000.0 -0.15 -0.3374 -0.9362 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D14 compound treatment 9.1713953E7 -5690000.0 -0.49 9.1051705E7 -3290000.0 -0.29 -0.5509 -0.9674 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D15 mock treatment 9.892053E7 1520000.0 0.13 9.8113622E7 3780000.0 0.33 0.3263 0.9179 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D16 mock treatment 9.4168648E7 -3240000.0 -0.28 8.9967288E7 -4370000.0 -0.38 -0.468 -0.9881 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D17 compound treatment 9.0682318E7 -6720000.0 -0.58 8.7690366E7 -6650000.0 -0.58 -0.8219 -1.0 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D18 compound treatment 9.6274157E7 -1130000.0 -0.1 9.5220455E7 883000.0 0.08 -0.0144 -0.1154 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D19 compound treatment 1.03542934E8 6140000.0 0.53 1.00578686E8 6240000.0 0.55 0.7612 0.9999 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D20 compound treatment 9.4746635E7 -2660000.0 -0.23 9.4064619E7 -273000.0 -0.02 -0.1792 -0.7764 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D21 compound treatment 9.9620302E7 2220000.0 0.19 9.9176905E7 4840000.0 0.42 0.4348 0.9356 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D22 compound treatment 1.0008539E8 2680000.0 0.23 9.8346697E7 4010000.0 0.35 0.4119 0.9797 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D23 compound treatment 1.13366659E8 1.6E7 1.38 1.03616085E8 9280000.0 0.81 1.5491 0.9681 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 D24 compound treatment 8.0171763E7 -1.72E7 -1.49 7.8865315E7 -1.55E7 -1.35 -2.0099 -0.9989 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E01 mock treatment 1.08843198E8 1.14E7 0.99 1.02179781E8 7840000.0 0.69 1.184 0.9842 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E02 mock treatment 1.02390163E8 4990000.0 0.43 1.00769387E8 6430000.0 0.56 0.7026 0.9913 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E03 compound treatment 1.00601598E8 3200000.0 0.28 9.8971858E7 4630000.0 0.41 0.4821 0.9824 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E04 compound treatment 9.1666298E7 -5740000.0 -0.5 9.0122601E7 -4210000.0 -0.37 -0.6113 -0.9894 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E05 compound treatment 9.6441759E7 -963000.0 -0.08 9.692296E7 2590000.0 0.23 0.1012 0.4199 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E06 compound treatment 9.5310228E7 -2090000.0 -0.18 9.2486575E7 -1850000.0 -0.16 -0.2424 -0.9985 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E07 compound treatment 9.7079364E7 -325000.0 -0.03 9.6928755E7 2590000.0 0.23 0.1405 0.6149 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E08 compound treatment 9.2652226E7 -4750000.0 -0.41 8.8138802E7 -6200000.0 -0.54 -0.6738 -0.9905 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E09 mock treatment 9.4810659E7 -2590000.0 -0.22 9.3008586E7 -1330000.0 -0.12 -0.2406 -0.9534 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E10 mock treatment 9.1065544E7 -6340000.0 -0.55 8.9839936E7 -4500000.0 -0.39 -0.6654 -0.9869 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E11 compound treatment 7.7073401E7 -2.03E7 -1.76 7.9564143E7 -1.48E7 -1.29 -2.1559 -0.9887 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E12 compound treatment 9.2106468E7 -5300000.0 -0.46 8.9845885E7 -4490000.0 -0.39 -0.6015 -0.9971 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E13 compound treatment 6.9548316E7 -2.79E7 -2.41 7.3490682E7 -2.08E7 -1.82 -2.9914 -0.9907 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E14 compound treatment 9.2442945E7 -4960000.0 -0.43 9.2031925E7 -2310000.0 -0.2 -0.4457 -0.9409 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E15 compound treatment 9.6864903E7 -539000.0 -0.05 9.7020521E7 2680000.0 0.23 0.1331 0.556 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E16 compound treatment 9.3393332E7 -4010000.0 -0.35 9.1769808E7 -2570000.0 -0.22 -0.4038 -0.978 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E17 mock treatment 1.04373362E8 6970000.0 0.6 9.9944111E7 5610000.0 0.49 0.7726 0.9949 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E18 mock treatment 1.05395774E8 7990000.0 0.69 1.00962212E8 6630000.0 0.58 0.8981 0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E19 compound treatment 7.7640839E7 -1.98E7 -1.71 7.736768E7 -1.7E7 -1.49 -2.2572 -0.9976 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E20 compound treatment 9.6638861E7 -765000.0 -0.07 9.7426336E7 3090000.0 0.27 0.1444 0.5189 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E21 compound treatment 7.7397624E7 -2.0E7 -1.73 7.9639999E7 -1.47E7 -1.29 -2.1314 -0.9894 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E22 compound treatment 7.5815206E7 -2.16E7 -1.86 7.5026996E7 -1.93E7 -1.69 -2.5135 -0.9988 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E23 compound treatment 7.6759504E7 -2.06E7 -1.78 7.8223783E7 -1.61E7 -1.41 -2.258 -0.9932 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 E24 compound treatment 3.813535E7 -5.93E7 -5.12 2.8501839E7 -6.58E7 -5.76 -7.694 -0.9983 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F01 mock treatment 1.03244776E8 5840000.0 0.5 1.01877221E8 7540000.0 0.66 0.8233 0.9912 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F02 mock treatment 1.029436E8 5540000.0 0.48 9.6824348E7 2490000.0 0.22 0.4922 0.9365 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F03 compound treatment 9.8728376E7 1320000.0 0.11 1.01417559E8 7080000.0 0.62 0.519 0.8237 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F04 compound treatment 9.6426891E7 -977000.0 -0.08 9.3378733E7 -958000.0 -0.08 -0.119 -1.0 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F05 compound treatment 1.00697557E8 3290000.0 0.28 1.00508999E8 6170000.0 0.54 0.5831 0.9551 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F06 compound treatment 9.3288597E7 -4120000.0 -0.36 8.9884683E7 -4450000.0 -0.39 -0.5269 -0.9989 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F07 compound treatment 1.01761708E8 4360000.0 0.38 9.8697477E7 4360000.0 0.38 0.536 1.0 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F08 compound treatment 9.4456981E7 -2950000.0 -0.25 9.1878085E7 -2460000.0 -0.22 -0.3322 -0.9965 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F09 mock treatment 9.5585179E7 -1820000.0 -0.16 9.5424131E7 1090000.0 0.1 -0.0438 -0.2387 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F10 mock treatment 9.1673082E7 -5730000.0 -0.5 9.1594864E7 -2740000.0 -0.24 -0.5197 -0.9448 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F11 compound treatment 9.9148393E7 1740000.0 0.15 9.8542418E7 4210000.0 0.37 0.3668 0.9223 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F12 compound treatment 8.3361283E7 -1.4E7 -1.21 8.1265852E7 -1.31E7 -1.14 -1.6666 -0.9996 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F13 compound treatment 9.283699E7 -4570000.0 -0.39 9.1815048E7 -2520000.0 -0.22 -0.435 -0.9624 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F14 compound treatment 8.991913E7 -7490000.0 -0.65 9.3930006E7 -407000.0 -0.04 -0.4824 -0.7449 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F15 compound treatment 8.3122266E7 -1.43E7 -1.23 8.0459327E7 -1.39E7 -1.21 -1.7311 -1.0 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F16 compound treatment 9.0397296E7 -7010000.0 -0.61 8.5994919E7 -8340000.0 -0.73 -0.9442 -0.9957 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F17 mock treatment 1.04382443E8 6980000.0 0.6 1.00516127E8 6180000.0 0.54 0.8086 0.9985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F18 mock treatment 1.03976158E8 6570000.0 0.57 9.9944798E7 5610000.0 0.49 0.7484 0.9974 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F19 compound treatment 7.3601414E7 -2.38E7 -2.06 7.6787242E7 -1.75E7 -1.54 -2.5398 -0.9897 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F20 compound treatment 9.9513542E7 2110000.0 0.18 9.5203804E7 867000.0 0.08 0.1824 0.9246 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F21 compound treatment 9.9890409E7 2490000.0 0.21 1.00081092E8 5740000.0 0.5 0.5073 0.928 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F22 compound treatment 9.9366729E7 1960000.0 0.17 9.7827963E7 3490000.0 0.31 0.3359 0.9614 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F23 compound treatment 1.06178786E8 8770000.0 0.76 1.03319765E8 8980000.0 0.79 1.0918 0.9998 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 F24 compound treatment 1.05301114E8 7900000.0 0.68 1.02690988E8 8350000.0 0.73 0.9993 0.9994 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G01 compound treatment 1.13899373E8 1.65E7 1.42 9.6007734E7 1670000.0 0.15 1.1108 0.7756 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G02 compound treatment 1.03004669E8 5600000.0 0.48 1.03798576E8 9460000.0 0.83 0.9275 0.9672 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G03 mock treatment 1.03498652E8 6090000.0 0.53 1.0101537E8 6680000.0 0.58 0.7855 0.9986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G04 mock treatment 9.4077332E7 -3330000.0 -0.29 9.7563959E7 3230000.0 0.28 -0.0035 -0.0087 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G05 compound treatment 1.00088721E8 2680000.0 0.23 9.4515166E7 178000.0 0.02 0.175 0.7529 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G06 compound treatment 7.1488928E7 -2.59E7 -2.24 7.4973205E7 -1.94E7 -1.69 -2.7811 -0.9906 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G07 compound treatment 6.9887306E7 -2.75E7 -2.38 7.0590927E7 -2.37E7 -2.08 -3.1501 -0.9978 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G08 compound treatment 9.3443851E7 -3960000.0 -0.34 9.2985648E7 -1350000.0 -0.12 -0.3255 -0.8994 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G09 compound treatment 9.4584128E7 -2820000.0 -0.24 9.5939894E7 1600000.0 0.14 -0.0731 -0.2599 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G10 compound treatment 9.1577518E7 -5830000.0 -0.5 8.9227367E7 -5110000.0 -0.45 -0.6721 -0.9983 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G11 compound treatment 9.7445649E7 41300.0 0.0 9.5385196E7 1050000.0 0.09 0.0674 0.7341 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G12 compound treatment 9.2908104E7 -4500000.0 -0.39 9.6510367E7 2170000.0 0.19 -0.1401 -0.324 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G13 compound treatment 9.5807221E7 -1600000.0 -0.14 9.3513756E7 -823000.0 -0.07 -0.1485 -0.9541 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G14 compound treatment 9.9463716E7 2060000.0 0.18 9.4019702E7 -317000.0 -0.03 0.1061 0.5895 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G15 compound treatment 9.3511122E7 -3890000.0 -0.34 9.302704E7 -1310000.0 -0.11 -0.3189 -0.8975 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G16 compound treatment 7.5664834E7 -2.17E7 -1.88 7.0042063E7 -2.43E7 -2.13 -2.8312 -0.9981 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G17 compound treatment 1.01767133E8 4360000.0 0.38 9.8289276E7 3950000.0 0.35 0.511 0.9991 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G18 compound treatment 6.8826142E7 -2.86E7 -2.47 7.1486908E7 -2.29E7 -2.0 -3.1595 -0.9945 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G19 mock treatment 1.02619658E8 5220000.0 0.45 9.8586511E7 4250000.0 0.37 0.5815 0.9955 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G20 mock treatment 1.02039476E8 4640000.0 0.4 9.7851095E7 3510000.0 0.31 0.5005 0.9915 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G21 compound treatment 7.6509383E7 -2.09E7 -1.8 7.6868109E7 -1.75E7 -1.53 -2.3572 -0.9966 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G22 compound treatment 1.03055815E8 5650000.0 0.49 9.8737183E7 4400000.0 0.39 0.6175 0.9931 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G23 compound treatment 1.08333514E8 1.09E7 0.94 1.01819942E8 7480000.0 0.65 1.1306 0.984 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 G24 compound treatment 1.08502484E8 1.11E7 0.96 1.0362593E8 9290000.0 0.81 1.2526 0.9966 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H01 compound treatment 1.10238351E8 1.28E7 1.11 1.03345474E8 9010000.0 0.79 1.3413 0.9861 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H02 compound treatment 1.00815863E8 3410000.0 0.29 9.6325572E7 1990000.0 0.17 0.3314 0.9684 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H03 mock treatment 1.04023212E8 6620000.0 0.57 1.0333354E8 9000000.0 0.79 0.961 0.9876 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H04 mock treatment 9.7083994E7 -320000.0 -0.03 9.4187845E7 -149000.0 -0.01 -0.0288 -0.9414 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H05 compound treatment 9.4750674E7 -2650000.0 -0.23 9.7523373E7 3190000.0 0.28 0.0351 0.0973 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H06 compound treatment 9.5406447E7 -2000000.0 -0.17 9.1502843E7 -2830000.0 -0.25 -0.2974 -0.9843 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H07 compound treatment 1.04603424E8 7200000.0 0.62 9.8959961E7 4620000.0 0.4 0.7258 0.9783 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H08 compound treatment 8.7960953E7 -9440000.0 -0.82 8.727211E7 -7070000.0 -0.62 -1.014 -0.9907 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H09 compound treatment 1.00490627E8 3090000.0 0.27 9.9106644E7 4770000.0 0.42 0.4836 0.9765 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H10 compound treatment 6.7945892E7 -2.95E7 -2.54 6.9765615E7 -2.46E7 -2.15 -3.3198 -0.9965 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H11 compound treatment 9.94294E7 2030000.0 0.17 9.585304E7 1520000.0 0.13 0.2175 0.9907 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H12 compound treatment 9.2266889E7 -5140000.0 -0.44 9.2885881E7 -1450000.0 -0.13 -0.4036 -0.8744 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H13 compound treatment 9.4038696E7 -3370000.0 -0.29 9.20869E7 -2250000.0 -0.2 -0.3448 -0.982 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H14 compound treatment 9.6176666E7 -1230000.0 -0.11 8.9898073E7 -4440000.0 -0.39 -0.3497 -0.8683 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H15 compound treatment 9.6362511E7 -1040000.0 -0.09 9.4017598E7 -320000.0 -0.03 -0.0834 -0.8851 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H16 compound treatment 8.8670178E7 -8730000.0 -0.75 8.3423244E7 -1.09E7 -0.96 -1.2088 -0.9932 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H17 compound treatment 1.00322617E8 2920000.0 0.25 9.9089593E7 4750000.0 0.42 0.4723 0.9712 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H18 compound treatment 8.9604063E7 -7800000.0 -0.67 8.9285307E7 -5050000.0 -0.44 -0.789 -0.9791 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H19 mock treatment 1.02720954E8 5320000.0 0.46 9.9490093E7 5150000.0 0.45 0.6436 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H20 mock treatment 9.9749871E7 2350000.0 0.2 9.569782E7 1360000.0 0.12 0.2275 0.9679 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H21 compound treatment 9.2456822E7 -4950000.0 -0.43 8.3537655E7 -1.08E7 -0.95 -0.9705 -0.9356 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H22 compound treatment 1.01625516E8 4220000.0 0.36 9.7646869E7 3310000.0 0.29 0.4626 0.9935 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H23 compound treatment 1.06718202E8 9310000.0 0.8 1.03038064E8 8700000.0 0.76 1.1073 0.9996 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 H24 compound treatment 1.05498691E8 8090000.0 0.7 1.03406241E8 9070000.0 0.79 1.0556 0.998 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I01 compound treatment 7.779917E7 -1.96E7 -1.69 8.0376747E7 -1.4E7 -1.22 -2.0613 -0.9872 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I02 compound treatment 1.01700801E8 4300000.0 0.37 1.00795216E8 6460000.0 0.57 0.6621 0.9792 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I03 compound treatment 1.03146834E8 5740000.0 0.5 1.02874243E8 8540000.0 0.75 0.879 0.9802 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I04 compound treatment 7.5124281E7 -2.23E7 -1.92 7.6517011E7 -1.78E7 -1.56 -2.4635 -0.9946 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I05 mock treatment 1.02187386E8 4780000.0 0.41 9.9337972E7 5000000.0 0.44 0.6016 0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I06 mock treatment 9.4012898E7 -3390000.0 -0.29 9.1460867E7 -2880000.0 -0.25 -0.3851 -0.9972 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I07 compound treatment 9.6652525E7 -752000.0 -0.06 9.4798276E7 461000.0 0.04 -0.0174 -0.2273 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I08 compound treatment 9.7002364E7 -402000.0 -0.03 9.7226454E7 2890000.0 0.25 0.1543 0.6043 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I09 compound treatment 9.8486959E7 1080000.0 0.09 9.4367023E7 29900.0 0.0 0.068 0.7266 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I10 compound treatment 6.7200378E7 -3.02E7 -2.61 7.1417968E7 -2.29E7 -2.01 -3.263 -0.9916 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I11 compound treatment 9.4327394E7 -3080000.0 -0.27 9.4480309E7 143000.0 0.01 -0.1791 -0.673 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I12 compound treatment 9.1012369E7 -6390000.0 -0.55 9.2142722E7 -2190000.0 -0.19 -0.5262 -0.9002 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I13 compound treatment 9.7772471E7 368000.0 0.03 9.719987E7 2860000.0 0.25 0.1996 0.7905 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I14 compound treatment 6.7740787E7 -2.97E7 -2.56 7.175909E7 -2.26E7 -1.98 -3.2089 -0.9918 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I15 compound treatment 9.5618102E7 -1790000.0 -0.15 9.6765059E7 2430000.0 0.21 0.0412 0.1567 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I16 compound treatment 9.435732E7 -3050000.0 -0.26 9.304748E7 -1290000.0 -0.11 -0.2659 -0.9286 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I17 compound treatment 9.890276E7 1500000.0 0.13 9.5463797E7 1130000.0 0.1 0.1612 0.991 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I18 compound treatment 9.9509714E7 2110000.0 0.18 9.5152948E7 816000.0 0.07 0.1791 0.9166 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I19 compound treatment 1.01229902E8 3830000.0 0.33 9.6764983E7 2430000.0 0.21 0.3839 0.9772 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I20 compound treatment 8.4580534E7 -1.28E7 -1.11 8.0034054E7 -1.43E7 -1.25 -1.6683 -0.9981 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I21 mock treatment 1.01583831E8 4180000.0 0.36 9.8895769E7 4560000.0 0.4 0.5374 0.9988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I22 mock treatment 9.9243531E7 1840000.0 0.16 9.1661907E7 -2680000.0 -0.23 -0.0532 -0.1881 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I23 compound treatment 1.08245802E8 1.08E7 0.94 1.03338945E8 9000000.0 0.79 1.2192 0.9963 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 I24 compound treatment 1.07072755E8 9670000.0 0.84 1.02975674E8 8640000.0 0.76 1.1251 0.9988 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J01 compound treatment 8.9968655E7 -7440000.0 -0.64 7.8576587E7 -1.58E7 -1.38 -1.4295 -0.9395 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J02 compound treatment 9.9555721E7 2150000.0 0.19 9.7842415E7 3510000.0 0.31 0.3483 0.9712 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J03 compound treatment 9.4121276E7 -3280000.0 -0.28 9.3535833E7 -801000.0 -0.07 -0.2501 -0.8562 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J04 compound treatment 9.1437969E7 -5970000.0 -0.52 9.1691564E7 -2650000.0 -0.23 -0.5281 -0.9348 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J05 mock treatment 1.014556E8 4050000.0 0.35 9.8491166E7 4150000.0 0.36 0.5045 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J06 mock treatment 9.1363948E7 -6040000.0 -0.52 9.1969316E7 -2370000.0 -0.21 -0.5154 -0.9182 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J07 compound treatment 9.9102204E7 1700000.0 0.15 9.7944743E7 3610000.0 0.32 0.3269 0.9392 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J08 compound treatment 8.5180162E7 -1.22E7 -1.06 8.3551167E7 -1.08E7 -0.94 -1.4141 -0.9984 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J09 compound treatment 9.72885E7 -116000.0 -0.01 9.642406E7 2090000.0 0.18 0.1221 0.6674 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J10 compound treatment 8.9981517E7 -7420000.0 -0.64 8.9907252E7 -4430000.0 -0.39 -0.7275 -0.971 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J11 compound treatment 9.7553203E7 149000.0 0.01 9.3381659E7 -956000.0 -0.08 -0.05 -0.5914 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J12 compound treatment 8.9467416E7 -7940000.0 -0.69 9.0423001E7 -3910000.0 -0.34 -0.727 -0.9486 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J13 compound treatment 9.6424764E7 -980000.0 -0.08 9.6331513E7 1990000.0 0.17 0.0636 0.3278 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J14 compound treatment 9.2976388E7 -4430000.0 -0.38 9.1159551E7 -3180000.0 -0.28 -0.4671 -0.9877 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J15 compound treatment 9.750498E7 101000.0 0.01 9.6844961E7 2510000.0 0.22 0.1613 0.7345 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J16 compound treatment 9.2880264E7 -4520000.0 -0.39 9.0418839E7 -3920000.0 -0.34 -0.5188 -0.9979 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J17 compound treatment 9.6412613E7 -992000.0 -0.09 9.0595896E7 -3740000.0 -0.33 -0.2921 -0.863 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J18 compound treatment 9.2847258E7 -4560000.0 -0.39 9.0575607E7 -3760000.0 -0.33 -0.5111 -0.9961 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J19 compound treatment 9.653737E7 -867000.0 -0.07 9.5518853E7 1180000.0 0.1 0.0202 0.158 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J20 compound treatment 2.0773811E7 -7.66E7 -6.62 2.0704411E7 -7.36E7 -6.44 -9.2369 -0.9999 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J21 mock treatment 1.02711959E8 5310000.0 0.46 9.8883537E7 4550000.0 0.4 0.6055 0.9975 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J22 mock treatment 9.7359899E7 -44400.0 0.0 8.9863477E7 -4470000.0 -0.39 -0.2796 -0.714 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J23 compound treatment 1.0620134E8 8800000.0 0.76 1.03625618E8 9290000.0 0.81 1.1121 0.9994 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 J24 compound treatment 9.9409845E7 2010000.0 0.17 9.789059E7 3550000.0 0.31 0.3424 0.9618 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K01 compound treatment 1.11887683E8 1.45E7 1.25 8.3589829E7 -1.07E7 -0.94 0.2195 0.1402 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K02 compound treatment 8.7362982E7 -1.0E7 -0.87 8.7386489E7 -6950000.0 -0.61 -1.0434 -0.9849 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K03 compound treatment 1.05161189E8 7760000.0 0.67 8.2202589E7 -1.21E7 -1.06 -0.2772 -0.2208 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K04 compound treatment 1.00538656E8 3130000.0 0.27 9.6597811E7 2260000.0 0.2 0.3313 0.9881 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K05 compound treatment 8.4948136E7 -1.25E7 -1.08 9.8512001E7 4170000.0 0.37 -0.5024 -0.4422 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K06 compound treatment 8.1321364E7 -1.61E7 -1.39 9.4254646E7 -82500.0 -0.01 -0.9874 -0.7108 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K07 mock treatment 1.00313265E8 2910000.0 0.25 9.3610368E7 -727000.0 -0.06 0.1327 0.5119 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K08 mock treatment 9.1631055E7 -5770000.0 -0.5 9.063261E7 -3700000.0 -0.32 -0.5819 -0.9783 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K09 compound treatment 9.864023E7 1240000.0 0.11 9.7478167E7 3140000.0 0.27 0.2699 0.9151 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K10 compound treatment 9.2527827E7 -4880000.0 -0.42 8.6805087E7 -7530000.0 -0.66 -0.7639 -0.9766 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K11 compound treatment 9.4279442E7 -3120000.0 -0.27 9.0409535E7 -3930000.0 -0.34 -0.4339 -0.9928 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K12 compound treatment 9.061723E7 -6790000.0 -0.59 9.0962163E7 -3380000.0 -0.3 -0.6234 -0.9497 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K13 compound treatment 9.9489036E7 2080000.0 0.18 9.9226306E7 4890000.0 0.43 0.4299 0.926 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K14 compound treatment 8.9116146E7 -8290000.0 -0.72 9.3475373E7 -862000.0 -0.08 -0.5595 -0.7773 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K15 mock treatment 9.5465099E7 -1940000.0 -0.17 9.1725392E7 -2610000.0 -0.23 -0.2801 -0.9883 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K16 mock treatment 9.2102764E7 -5300000.0 -0.46 9.5102828E7 766000.0 0.07 -0.2764 -0.5973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K17 compound treatment 1.03237728E8 5830000.0 0.5 9.7108314E7 2770000.0 0.24 0.5278 0.9438 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K18 compound treatment 9.7311358E7 -93000.0 -0.01 9.3533257E7 -804000.0 -0.07 -0.0554 -0.7827 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K19 compound treatment 7.8872556E7 -1.85E7 -1.6 7.9553146E7 -1.48E7 -1.29 -2.0467 -0.9944 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K20 compound treatment 1.00123616E8 2720000.0 0.23 9.4195827E7 -141000.0 -0.01 0.1573 0.6689 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K21 compound treatment 1.03674821E8 6270000.0 0.54 1.03556097E8 9220000.0 0.81 0.9535 0.9812 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K22 compound treatment 1.01523479E8 4120000.0 0.36 1.01364603E8 7030000.0 0.62 0.6865 0.9661 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K23 mock treatment 1.02224777E8 4820000.0 0.42 8.3021726E7 -1.13E7 -0.99 -0.4058 -0.3778 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 K24 mock treatment 1.07220431E8 9820000.0 0.85 9.9884087E7 5550000.0 0.49 0.9428 0.965 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L01 compound treatment 1.04697428E8 7290000.0 0.63 8.8190595E7 -6150000.0 -0.54 0.065 0.0785 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L02 compound treatment 8.5637528E7 -1.18E7 -1.02 8.2660395E7 -1.17E7 -1.02 -1.4413 -1.0 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L03 compound treatment 1.03476015E8 6070000.0 0.52 8.0749711E7 -1.36E7 -1.19 -0.47 -0.3617 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L04 compound treatment 9.6958095E7 -446000.0 -0.04 9.549817E7 1160000.0 0.1 0.0446 0.4104 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L05 compound treatment 8.1020029E7 -1.64E7 -1.42 9.0552641E7 -3780000.0 -0.33 -1.2349 -0.8496 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L06 compound treatment 7.2306428E7 -2.51E7 -2.17 9.4069193E7 -268000.0 -0.02 -1.5494 -0.7147 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L07 mock treatment 1.02027666E8 4620000.0 0.4 9.3813469E7 -524000.0 -0.05 0.25 0.6219 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L08 mock treatment 9.4460993E7 -2940000.0 -0.25 9.2339067E7 -2000000.0 -0.17 -0.3034 -0.9833 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L09 compound treatment 9.2796625E7 -4610000.0 -0.4 9.2302782E7 -2030000.0 -0.18 -0.4073 -0.9342 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L10 compound treatment 8.7139931E7 -1.03E7 -0.89 8.1455675E7 -1.29E7 -1.13 -1.4241 -0.9929 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L11 compound treatment 9.0910191E7 -6490000.0 -0.56 8.3007097E7 -1.13E7 -0.99 -1.0978 -0.9636 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L12 compound treatment 9.2534334E7 -4870000.0 -0.42 8.7747393E7 -6590000.0 -0.58 -0.7052 -0.988 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L13 compound treatment 9.534124E7 -2060000.0 -0.18 9.096452E7 -3370000.0 -0.3 -0.3347 -0.9708 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L14 compound treatment 8.51419E7 -1.23E7 -1.06 8.2915265E7 -1.14E7 -1.0 -1.4558 -0.9996 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L15 mock treatment 9.9025262E7 1620000.0 0.14 9.5143425E7 806000.0 0.07 0.1489 0.9497 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L16 mock treatment 9.4007109E7 -3400000.0 -0.29 9.1105184E7 -3230000.0 -0.28 -0.4075 -0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L17 compound treatment 9.1088618E7 -6320000.0 -0.55 8.8798407E7 -5540000.0 -0.48 -0.7285 -0.9983 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L18 compound treatment 9.8768878E7 1360000.0 0.12 9.2836127E7 -1500000.0 -0.13 -0.0096 -0.0541 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L19 compound treatment 9.8040999E7 637000.0 0.05 9.5477834E7 1140000.0 0.1 0.1095 0.9605 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L20 compound treatment 1.00669838E8 3270000.0 0.28 9.6844787E7 2510000.0 0.22 0.3546 0.9923 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L21 compound treatment 1.03631972E8 6230000.0 0.54 9.6494582E7 2160000.0 0.19 0.5139 0.9014 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L22 compound treatment 1.02453832E8 5050000.0 0.44 9.7574271E7 3240000.0 0.28 0.5087 0.9782 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L23 mock treatment 1.05876798E8 8470000.0 0.73 9.1429407E7 -2910000.0 -0.25 0.3375 0.4356 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 L24 mock treatment 1.07124769E8 9720000.0 0.84 8.8581905E7 -5760000.0 -0.5 0.2375 0.2426 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M01 compound treatment 1.09905578E8 1.25E7 1.08 1.04508223E8 1.02E7 0.89 1.3929 0.9954 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M02 compound treatment 9.2792881E7 -4610000.0 -0.4 8.9564829E7 -4770000.0 -0.42 -0.577 -0.9997 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M03 compound treatment 1.03795178E8 6390000.0 0.55 9.8136745E7 3800000.0 0.33 0.6255 0.9706 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M04 compound treatment 9.6295579E7 -1110000.0 -0.1 9.1682868E7 -2650000.0 -0.23 -0.232 -0.9232 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M05 compound treatment 6.8310023E7 -2.91E7 -2.51 6.5247192E7 -2.91E7 -2.55 -3.5771 -1.0 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M06 compound treatment 9.6291358E7 -1110000.0 -0.1 8.7937656E7 -6400000.0 -0.56 -0.464 -0.8165 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M07 compound treatment 7.8546979E7 -1.89E7 -1.63 7.6273249E7 -1.81E7 -1.58 -2.2696 -0.9999 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M08 compound treatment 7.0257188E7 -2.71E7 -2.34 7.2032471E7 -2.23E7 -1.95 -3.0383 -0.9958 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M09 mock treatment 7.821396E7 -1.92E7 -1.66 8.2051299E7 -1.23E7 -1.08 -1.9323 -0.978 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M10 mock treatment 9.0682189E7 -6720000.0 -0.58 9.7745299E7 3410000.0 0.3 -0.1996 -0.3059 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M11 compound treatment 8.1699973E7 -1.57E7 -1.36 8.0871423E7 -1.35E7 -1.18 -1.7925 -0.9975 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M12 compound treatment 8.6205043E7 -1.12E7 -0.97 7.9053483E7 -1.53E7 -1.34 -1.6298 -0.9873 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M13 mock treatment 9.1519234E7 -5890000.0 -0.51 9.1551672E7 -2790000.0 -0.24 -0.5318 -0.9433 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M14 mock treatment 9.2539821E7 -4860000.0 -0.42 8.543053E7 -8910000.0 -0.78 -0.8483 -0.958 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M15 compound treatment 9.1073396E7 -6330000.0 -0.55 8.4092736E7 -1.02E7 -0.9 -1.0206 -0.9719 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M16 compound treatment 7.2905848E7 -2.45E7 -2.12 8.617959E7 -8160000.0 -0.71 -2.0011 -0.8961 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M17 compound treatment 9.9342801E7 1940000.0 0.17 7.329816E7 -2.1E7 -1.84 -1.1836 -0.6402 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M18 compound treatment 9.8406843E7 1000000.0 0.09 8.6691256E7 -7650000.0 -0.67 -0.4119 -0.6105 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M19 compound treatment 6.2502695E7 -3.49E7 -3.01 7.5576871E7 -1.88E7 -1.64 -3.2926 -0.9592 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M20 compound treatment 9.0793679E7 -6610000.0 -0.57 8.8137042E7 -6200000.0 -0.54 -0.7874 -0.9997 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M21 compound treatment 1.04372696E8 6970000.0 0.6 8.6787049E7 -7550000.0 -0.66 -0.0416 -0.0466 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M22 compound treatment 7.2547648E7 -2.49E7 -2.15 7.4660172E7 -1.97E7 -1.72 -2.7358 -0.994 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M23 compound treatment 7.1900069E7 -2.55E7 -2.2 7.3889823E7 -2.04E7 -1.79 -2.823 -0.9947 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 M24 compound treatment 8.1722961E7 -1.57E7 -1.35 7.8579953E7 -1.58E7 -1.38 -1.9329 -1.0 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N01 compound treatment 1.05326004E8 7920000.0 0.68 1.03819637E8 9480000.0 0.83 1.0706 0.9954 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N02 compound treatment 9.9870315E7 2470000.0 0.21 9.0394086E7 -3940000.0 -0.35 -0.0934 -0.2303 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N03 compound treatment 1.05655357E8 8250000.0 0.71 1.01884498E8 7550000.0 0.66 0.971 0.9993 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N04 compound treatment 9.2093607E7 -5310000.0 -0.46 9.3428767E7 -908000.0 -0.08 -0.3806 -0.8175 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N05 compound treatment 9.9424461E7 2020000.0 0.17 9.0794396E7 -3540000.0 -0.31 -0.0959 -0.2694 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N06 compound treatment 9.6019797E7 -1380000.0 -0.12 9.0782315E7 -3550000.0 -0.31 -0.3045 -0.9137 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N07 compound treatment 9.4847367E7 -2560000.0 -0.22 9.5397416E7 1060000.0 0.09 -0.0906 -0.378 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N08 compound treatment 9.6394837E7 -1010000.0 -0.09 8.3385409E7 -1.1E7 -0.96 -0.7394 -0.7683 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N09 mock treatment 9.223973E7 -5160000.0 -0.45 8.8363903E7 -5970000.0 -0.52 -0.6851 -0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N10 mock treatment 9.2647983E7 -4760000.0 -0.41 9.4903912E7 567000.0 0.05 -0.2554 -0.6173 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N11 compound treatment 7.9828234E7 -1.76E7 -1.52 8.2408859E7 -1.19E7 -1.04 -1.8116 -0.9833 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N12 compound treatment 8.4269976E7 -1.31E7 -1.13 8.5283458E7 -9050000.0 -0.79 -1.3625 -0.9846 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N13 mock treatment 9.6128502E7 -1280000.0 -0.11 8.9296611E7 -5040000.0 -0.44 -0.3899 -0.8574 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N14 mock treatment 9.0580902E7 -6820000.0 -0.59 8.2742542E7 -1.16E7 -1.01 -1.1343 -0.9666 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N15 compound treatment 9.1588219E7 -5820000.0 -0.5 8.3954872E7 -1.04E7 -0.91 -0.9977 -0.961 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N16 compound treatment 8.3395613E7 -1.4E7 -1.21 9.1313672E7 -3020000.0 -0.26 -1.0427 -0.8418 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N17 compound treatment 1.00721435E8 3320000.0 0.29 9.0274969E7 -4060000.0 -0.36 -0.0488 -0.1069 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N18 compound treatment 8.542382E7 -1.2E7 -1.03 9.0312235E7 -4020000.0 -0.35 -0.9808 -0.8973 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N19 compound treatment 8.925273E7 -8150000.0 -0.7 9.4163841E7 -173000.0 -0.02 -0.5086 -0.7222 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N20 compound treatment 5.3981314E7 -4.34E7 -3.75 4.9779752E7 -4.46E7 -3.9 -5.4094 -0.9998 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N21 compound treatment 1.0200382E8 4600000.0 0.4 7.8700575E7 -1.56E7 -1.37 -0.6867 -0.4819 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N22 compound treatment 1.0194674E8 4540000.0 0.39 8.1354428E7 -1.3E7 -1.14 -0.526 -0.4376 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N23 compound treatment 1.06811963E8 9410000.0 0.81 9.173411E7 -2600000.0 -0.23 0.4135 0.49 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 N24 compound treatment 1.04956636E8 7550000.0 0.65 1.04423787E8 1.01E7 0.88 1.0855 0.9889 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O01 compound treatment 9.4867397E7 -2540000.0 -0.22 8.5602352E7 -8730000.0 -0.76 -0.6955 -0.8746 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O02 compound treatment 8.6907963E7 -1.05E7 -0.91 8.5319167E7 -9020000.0 -0.79 -1.1991 -0.9976 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O03 compound treatment 6.1059882E7 -3.63E7 -3.14 7.0591485E7 -2.37E7 -2.08 -3.6892 -0.9799 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O04 compound treatment 7.6732399E7 -2.07E7 -1.79 9.9502455E7 5170000.0 0.45 -0.9429 -0.5119 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O05 compound treatment 7.2811629E7 -2.46E7 -2.12 7.6285821E7 -1.81E7 -1.58 -2.6191 -0.9894 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O06 compound treatment 9.5297861E7 -2110000.0 -0.18 9.5865867E7 1530000.0 0.13 -0.034 -0.1508 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O07 compound treatment 7.111767E7 -2.63E7 -2.27 7.5844866E7 -1.85E7 -1.62 -2.7498 -0.9862 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O08 compound treatment 7.0581843E7 -2.68E7 -2.32 6.9578567E7 -2.48E7 -2.17 -3.1703 -0.9994 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O09 compound treatment 9.3016365E7 -4390000.0 -0.38 9.2101689E7 -2240000.0 -0.2 -0.4063 -0.9527 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O10 compound treatment 7.8742307E7 -1.87E7 -1.61 9.0661178E7 -3680000.0 -0.32 -1.3673 -0.8318 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O11 mock treatment 9.0798195E7 -6610000.0 -0.57 9.2219844E7 -2120000.0 -0.19 -0.5345 -0.8909 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O12 mock treatment 8.5371959E7 -1.2E7 -1.04 8.9062285E7 -5270000.0 -0.46 -1.0613 -0.9333 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O13 compound treatment 9.4358475E7 -3050000.0 -0.26 9.282214E7 -1520000.0 -0.13 -0.2798 -0.9497 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O14 compound treatment 9.2796651E7 -4610000.0 -0.4 8.9731245E7 -4610000.0 -0.4 -0.5664 -1.0 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O15 compound treatment 9.5087897E7 -2320000.0 -0.2 9.4081665E7 -256000.0 -0.02 -0.1573 -0.7813 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O16 compound treatment 9.2688079E7 -4720000.0 -0.41 9.0297865E7 -4040000.0 -0.35 -0.538 -0.9975 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O17 compound treatment 8.121896E7 -1.62E7 -1.4 8.0864647E7 -1.35E7 -1.18 -1.8223 -0.9964 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O18 compound treatment 7.3742841E7 -2.37E7 -2.04 7.3748833E7 -2.06E7 -1.8 -2.7192 -0.998 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O19 compound treatment 7.6730881E7 -2.07E7 -1.79 7.5153366E7 -1.92E7 -1.68 -2.4498 -0.9995 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O20 compound treatment 1.01594677E8 4190000.0 0.36 9.7524691E7 3190000.0 0.28 0.4532 0.9917 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O21 compound treatment 1.08668666E8 1.13E7 0.97 1.0237276E8 8040000.0 0.7 1.1852 0.9873 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O22 compound treatment 1.03071527E8 5670000.0 0.49 1.0064803E8 6310000.0 0.55 0.7367 0.9982 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O23 compound treatment 1.06067519E8 8660000.0 0.75 1.01112734E8 6780000.0 0.59 0.9484 0.9934 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 O24 compound treatment 1.04555892E8 7150000.0 0.62 1.00662775E8 6330000.0 0.55 0.8282 0.9985 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P01 compound treatment 9.2351414E7 -5050000.0 -0.44 7.7619444E7 -1.67E7 -1.46 -1.3432 -0.8797 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P02 compound treatment 8.5399235E7 -1.2E7 -1.04 9.8710715E7 4370000.0 0.38 -0.4626 -0.4185 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P03 compound treatment 8.0991356E7 -1.64E7 -1.42 8.1186596E7 -1.32E7 -1.15 -1.8162 -0.9947 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P04 compound treatment 8.0997494E7 -1.64E7 -1.42 9.8169334E7 3830000.0 0.34 -0.7649 -0.5252 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P05 compound treatment 1.01212407E8 3810000.0 0.33 9.448855E7 151000.0 0.01 0.2419 0.735 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P06 compound treatment 8.751706E7 -9890000.0 -0.85 8.6162805E7 -8170000.0 -0.72 -1.1097 -0.9961 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P07 compound treatment 9.7038584E7 -366000.0 -0.03 9.6357475E7 2020000.0 0.18 0.1027 0.5717 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P08 compound treatment 9.6284751E7 -1120000.0 -0.1 9.1765747E7 -2570000.0 -0.23 -0.2275 -0.9288 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P09 compound treatment 9.6010501E7 -1390000.0 -0.12 9.2350021E7 -1990000.0 -0.17 -0.2081 -0.9839 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P10 compound treatment 8.9675537E7 -7730000.0 -0.67 8.5544415E7 -8790000.0 -0.77 -1.0162 -0.9975 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P11 mock treatment 9.5470895E7 -1930000.0 -0.17 9.0002685E7 -4330000.0 -0.38 -0.3863 -0.9321 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P12 mock treatment 9.1442997E7 -5960000.0 -0.51 8.8641527E7 -5700000.0 -0.5 -0.7166 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P13 compound treatment 9.0139309E7 -7270000.0 -0.63 8.8056236E7 -6280000.0 -0.55 -0.8324 -0.9978 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P14 compound treatment 9.1450708E7 -5950000.0 -0.51 8.919351E7 -5140000.0 -0.45 -0.6819 -0.9978 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P15 compound treatment 9.7066925E7 -337000.0 -0.03 9.2164887E7 -2170000.0 -0.19 -0.155 -0.8061 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P16 compound treatment 9.2270433E7 -5130000.0 -0.44 8.764608E7 -6690000.0 -0.59 -0.7276 -0.9906 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P17 compound treatment 8.9544317E7 -7860000.0 -0.68 8.463868E7 -9700000.0 -0.85 -1.0802 -0.9939 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P18 compound treatment 8.8025628E7 -9380000.0 -0.81 8.2457842E7 -1.19E7 -1.04 -1.3079 -0.9924 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P19 compound treatment 1.01613497E8 4210000.0 0.36 9.6770421E7 2430000.0 0.21 0.4077 0.9675 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P20 compound treatment 1.01680684E8 4280000.0 0.37 9.4611471E7 274000.0 0.02 0.2782 0.7515 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P21 compound treatment 1.05450309E8 8050000.0 0.69 1.02124857E8 7790000.0 0.68 0.9733 1.0 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P22 compound treatment 1.04044362E8 6640000.0 0.57 9.8945824E7 4610000.0 0.4 0.6907 0.9852 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P23 compound treatment 7.7865321E7 -1.95E7 -1.69 7.6045627E7 -1.83E7 -1.6 -2.3253 -0.9997 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2096 P24 compound treatment 1.05678981E8 8270000.0 0.71 9.9628386E7 5290000.0 0.46 0.8328 0.9779 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A01 compound treatment 1.12777518E8 1.62E7 1.4 1.0514235E8 1.01E7 0.88 1.6138 0.975 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A02 compound treatment 1.06117883E8 9560000.0 0.83 9.8439268E7 3370000.0 0.29 0.7923 0.9035 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A03 compound treatment 9.8095647E7 1540000.0 0.13 9.1888332E7 -3190000.0 -0.28 -0.1031 -0.3337 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A04 compound treatment 1.0115562E8 4600000.0 0.4 9.9578867E7 4510000.0 0.39 0.5597 1.0 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A05 compound treatment 9.0816419E7 -5740000.0 -0.5 1.0256516E8 7490000.0 0.66 0.1131 0.1376 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A06 compound treatment 3.3885555E7 -6.27E7 -5.41 3.762106E7 -5.75E7 -5.03 -7.383 -0.9993 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A07 compound treatment 1.0535783E8 8800000.0 0.76 9.4816638E7 -257000.0 -0.02 0.5217 0.6859 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A08 compound treatment 9.8876752E7 2320000.0 0.2 9.9763927E7 4690000.0 0.41 0.432 0.9457 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A09 compound treatment 1.01862114E8 5310000.0 0.46 1.00327245E8 5250000.0 0.46 0.6492 1.0 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A10 compound treatment 7.4193139E7 -2.24E7 -1.93 7.8894534E7 -1.62E7 -1.42 -2.367 -0.9883 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A11 compound treatment 1.01224934E8 4670000.0 0.4 8.8199434E7 -6870000.0 -0.6 -0.1403 -0.1936 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A12 compound treatment 9.9065027E7 2510000.0 0.22 9.6454546E7 1380000.0 0.12 0.2387 0.9619 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A13 mock treatment 9.6955302E7 400000.0 0.03 9.6224055E7 1150000.0 0.1 0.0956 0.8982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A14 mock treatment 9.6051774E7 -504000.0 -0.04 9.2972643E7 -2100000.0 -0.18 -0.1608 -0.851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A15 compound treatment 7.2749239E7 -2.38E7 -2.06 7.0874771E7 -2.42E7 -2.12 -2.9515 -0.9999 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A16 compound treatment 1.02266318E8 5710000.0 0.49 9.4405797E7 -668000.0 -0.06 0.3074 0.619 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A17 compound treatment 9.6456411E7 -99400.0 -0.01 9.2437298E7 -2640000.0 -0.23 -0.1692 -0.7329 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A18 compound treatment 9.8829524E7 2270000.0 0.2 9.4711885E7 -362000.0 -0.03 0.1165 0.5855 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A19 compound treatment 9.398751E7 -2570000.0 -0.22 9.4859567E7 -214000.0 -0.02 -0.1701 -0.7642 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A20 compound treatment 9.844652E7 1890000.0 0.16 1.01357974E8 6280000.0 0.55 0.5044 0.8791 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A21 compound treatment 9.834637E7 1790000.0 0.15 9.7201871E7 2130000.0 0.19 0.2411 0.9957 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A22 compound treatment 9.4748926E7 -1810000.0 -0.16 9.4434005E7 -640000.0 -0.06 -0.1499 -0.9044 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A23 compound treatment 6.1725278E7 -3.48E7 -3.01 6.5461824E7 -2.96E7 -2.59 -3.9598 -0.9972 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 A24 compound treatment 9.8207305E7 1650000.0 0.14 9.7859769E7 2790000.0 0.24 0.2733 0.9674 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B01 compound treatment 9.9427672E7 2870000.0 0.25 9.415335E7 -920000.0 -0.08 0.1184 0.4541 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B02 compound treatment 8.0284218E7 -1.63E7 -1.41 8.7032731E7 -8040000.0 -0.7 -1.4914 -0.9489 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B03 compound treatment 9.9185445E7 2630000.0 0.23 1.00211963E8 5140000.0 0.45 0.4786 0.95 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B04 compound treatment 1.01239198E8 4680000.0 0.4 9.1767953E7 -3310000.0 -0.29 0.0815 0.1638 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B05 compound treatment 1.0142158E8 4870000.0 0.42 9.9594195E7 4520000.0 0.4 0.5769 0.9995 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B06 compound treatment 8.8011858E7 -8540000.0 -0.74 9.2997236E7 -2080000.0 -0.18 -0.6503 -0.8557 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B07 compound treatment 4.0854369E7 -5.57E7 -4.81 4.4741983E7 -5.03E7 -4.4 -6.5167 -0.999 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B08 compound treatment 9.3938011E7 -2620000.0 -0.23 9.5091602E7 17800.0 0.0 -0.1588 -0.7022 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B09 compound treatment 9.3845476E7 -2710000.0 -0.23 8.9472815E7 -5600000.0 -0.49 -0.5121 -0.9428 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B10 compound treatment 8.7122915E7 -9430000.0 -0.81 9.2462251E7 -2610000.0 -0.23 -0.7377 -0.8718 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B11 compound treatment 1.00734478E8 4180000.0 0.36 9.2354281E7 -2720000.0 -0.24 0.0869 0.201 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B12 compound treatment 9.1789278E7 -4770000.0 -0.41 9.3360072E7 -1710000.0 -0.15 -0.3972 -0.9064 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B13 mock treatment 9.5370666E7 -1190000.0 -0.1 9.8419306E7 3350000.0 0.29 0.1347 0.4341 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B14 mock treatment 8.6237988E7 -1.03E7 -0.89 8.5701647E7 -9370000.0 -0.82 -1.2101 -0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B15 compound treatment 1.02101573E8 5550000.0 0.48 1.01171022E8 6100000.0 0.53 0.716 0.9985 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B16 compound treatment 9.1986465E7 -4570000.0 -0.39 9.4228857E7 -845000.0 -0.07 -0.3314 -0.8252 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B17 compound treatment 9.6729341E7 174000.0 0.01 1.00229638E8 5160000.0 0.45 0.3297 0.7302 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B18 compound treatment 4.1777244E7 -5.48E7 -4.73 3.5780787E7 -5.93E7 -5.19 -7.0149 -0.9989 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B19 compound treatment 9.7253243E7 697000.0 0.06 1.01090252E8 6020000.0 0.53 0.4149 0.7829 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B20 compound treatment 9.2613262E7 -3940000.0 -0.34 9.4723648E7 -350000.0 -0.03 -0.2625 -0.7676 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B21 compound treatment 1.08168561E8 1.16E7 1.0 1.04033643E8 8960000.0 0.78 1.2637 0.9926 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B22 compound treatment 9.2820307E7 -3740000.0 -0.32 8.9386421E7 -5690000.0 -0.5 -0.5801 -0.978 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B23 compound treatment 9.9804089E7 3250000.0 0.28 1.02108072E8 7030000.0 0.62 0.6337 0.9367 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 B24 compound treatment 1.08203114E8 1.16E7 1.01 1.03797883E8 8720000.0 0.76 1.2512 0.9907 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C01 compound treatment 1.05819998E8 9260000.0 0.8 1.02434211E8 7360000.0 0.64 1.0213 0.9942 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C02 compound treatment 1.05627795E8 9070000.0 0.78 1.00295188E8 5220000.0 0.46 0.8772 0.967 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C03 compound treatment 7.9284711E7 -1.73E7 -1.49 7.0187882E7 -2.49E7 -2.18 -2.5949 -0.983 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C04 compound treatment 8.4970164E7 -1.16E7 -1.0 8.8461788E7 -6610000.0 -0.58 -1.1168 -0.9661 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C05 compound treatment 1.0188066E8 5320000.0 0.46 9.8815907E7 3740000.0 0.33 0.5568 0.9862 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C06 compound treatment 1.01125867E8 4570000.0 0.39 9.385881E7 -1220000.0 -0.11 0.2039 0.4988 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C07 compound treatment 9.584306E7 -713000.0 -0.06 8.6995226E7 -8080000.0 -0.71 -0.5435 -0.7658 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C08 compound treatment 9.2627493E7 -3930000.0 -0.34 9.4189022E7 -885000.0 -0.08 -0.2947 -0.8467 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C09 compound treatment 7.9597531E7 -1.7E7 -1.46 8.7805595E7 -7270000.0 -0.64 -1.4855 -0.9303 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C10 compound treatment 9.350177E7 -3050000.0 -0.26 9.2366144E7 -2710000.0 -0.24 -0.3541 -0.9986 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C11 mock treatment 9.6220454E7 -335000.0 -0.03 8.8397817E7 -6680000.0 -0.58 -0.4336 -0.7412 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C12 mock treatment 8.9120969E7 -7430000.0 -0.64 9.3208298E7 -1870000.0 -0.16 -0.5695 -0.8595 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C13 compound treatment 7.5553485E7 -2.1E7 -1.81 7.1842131E7 -2.32E7 -2.03 -2.7204 -0.9984 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C14 compound treatment 2.0576592E7 -7.6E7 -6.56 1.999068E7 -7.51E7 -6.57 -9.2869 -1.0 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C15 mock treatment 9.0350276E7 -6210000.0 -0.54 9.593248E7 859000.0 0.08 -0.3259 -0.6021 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C16 mock treatment 8.8720883E7 -7830000.0 -0.68 9.5852952E7 779000.0 0.07 -0.4303 -0.6327 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C17 compound treatment 9.9008084E7 2450000.0 0.21 9.5720705E7 647000.0 0.06 0.1898 0.8657 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C18 compound treatment 9.8296242E7 1740000.0 0.15 8.688939E7 -8180000.0 -0.72 -0.4002 -0.5468 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C19 compound treatment 1.01852359E8 5300000.0 0.46 1.02049622E8 6980000.0 0.61 0.7552 0.9899 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C20 compound treatment 1.9975605E7 -7.66E7 -6.61 2.0738612E7 -7.43E7 -6.51 -9.2773 -1.0 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C21 compound treatment 6.5950138E7 -3.06E7 -2.64 6.8394153E7 -2.67E7 -2.33 -3.5203 -0.9981 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C22 compound treatment 9.5738517E7 -817000.0 -0.07 9.330348E7 -1770000.0 -0.15 -0.1595 -0.9366 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C23 compound treatment 9.6221675E7 -334000.0 -0.03 9.9079366E7 4010000.0 0.35 0.2275 0.6467 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 C24 compound treatment 1.00347707E8 3790000.0 0.33 1.04361458E8 9290000.0 0.81 0.8063 0.9201 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D01 compound treatment 1.01033666E8 4480000.0 0.39 9.6194341E7 1120000.0 0.1 0.3428 0.8592 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D02 compound treatment 9.9976117E7 3420000.0 0.3 9.8137896E7 3060000.0 0.27 0.3985 0.9988 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D03 compound treatment 1.06652619E8 1.01E7 0.87 1.0334606E8 8270000.0 0.72 1.1286 0.9957 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D04 compound treatment 8.8910314E7 -7650000.0 -0.66 9.2832451E7 -2240000.0 -0.2 -0.6056 -0.8792 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D05 compound treatment 9.9538717E7 2980000.0 0.26 9.0648503E7 -4430000.0 -0.39 -0.0917 -0.1971 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D06 compound treatment 8.993349E7 -6620000.0 -0.57 9.0997682E7 -4080000.0 -0.36 -0.6567 -0.9742 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D07 compound treatment 1.03172193E8 6620000.0 0.57 9.9811929E7 4740000.0 0.41 0.6973 0.9876 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D08 compound treatment 7.2324634E7 -2.42E7 -2.09 7.404272E7 -2.1E7 -1.84 -2.7814 -0.9979 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D09 compound treatment 8.6309008E7 -1.02E7 -0.89 8.255603E7 -1.25E7 -1.1 -1.4005 -0.9944 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D10 compound treatment 7.858765E7 -1.8E7 -1.55 7.7750874E7 -1.73E7 -1.52 -2.1694 -0.9999 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D11 mock treatment 9.7727281E7 1170000.0 0.1 1.0059479E8 5520000.0 0.48 0.4132 0.837 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D12 mock treatment 8.5915536E7 -1.06E7 -0.92 9.2937568E7 -2140000.0 -0.19 -0.782 -0.8339 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D13 compound treatment 9.3241469E7 -3310000.0 -0.29 9.3722727E7 -1350000.0 -0.12 -0.286 -0.9235 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D14 compound treatment 9.1363378E7 -5190000.0 -0.45 8.9218838E7 -5850000.0 -0.51 -0.6795 -0.9978 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D15 mock treatment 9.7187499E7 632000.0 0.05 9.7547011E7 2470000.0 0.22 0.1916 0.8585 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D16 mock treatment 8.6496943E7 -1.01E7 -0.87 9.3689979E7 -1380000.0 -0.12 -0.7 -0.798 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D17 compound treatment 8.5470237E7 -1.11E7 -0.96 8.1021452E7 -1.41E7 -1.23 -1.5467 -0.9923 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D18 compound treatment 9.6395259E7 -161000.0 -0.01 9.167598E7 -3400000.0 -0.3 -0.2201 -0.7393 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D19 compound treatment 1.04025287E8 7470000.0 0.65 1.0329214E8 8220000.0 0.72 0.9648 0.9985 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D20 compound treatment 9.3382701E7 -3170000.0 -0.27 9.610452E7 1030000.0 0.09 -0.13 -0.4506 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D21 compound treatment 1.05020467E8 8460000.0 0.73 9.6182668E7 1110000.0 0.1 0.5856 0.794 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D22 compound treatment 7.4184336E7 -2.24E7 -1.93 7.5858597E7 -1.92E7 -1.68 -2.5554 -0.9976 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D23 compound treatment 1.03215958E8 6660000.0 0.58 1.03853809E8 8780000.0 0.77 0.9501 0.9898 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 D24 compound treatment 1.0960889E8 1.31E7 1.13 9.7552781E7 2480000.0 0.22 0.9506 0.828 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E01 mock treatment 1.07341009E8 1.08E7 0.93 9.9858791E7 4780000.0 0.42 0.9548 0.9349 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E02 mock treatment 1.00008776E8 3450000.0 0.3 9.5689627E7 616000.0 0.05 0.249 0.8216 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E03 compound treatment 8.7690663E7 -8870000.0 -0.77 8.3733764E7 -1.13E7 -0.99 -1.2432 -0.9918 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E04 compound treatment 9.9936974E7 3380000.0 0.29 9.22122E7 -2860000.0 -0.25 0.0294 0.0765 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E05 compound treatment 3.0350068E7 -6.62E7 -5.72 3.4244638E7 -6.08E7 -5.32 -7.8078 -0.9994 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E06 compound treatment 7.2372863E7 -2.42E7 -2.09 7.2572244E7 -2.25E7 -1.97 -2.8695 -0.9996 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E07 compound treatment 9.9515998E7 2960000.0 0.26 9.5969278E7 895000.0 0.08 0.2362 0.8833 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E08 compound treatment 9.3611252E7 -2940000.0 -0.25 9.0287472E7 -4790000.0 -0.42 -0.476 -0.9714 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E09 mock treatment 9.4483562E7 -2070000.0 -0.18 9.2292244E7 -2780000.0 -0.24 -0.2987 -0.9886 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E10 mock treatment 9.1601454E7 -4950000.0 -0.43 8.9811816E7 -5260000.0 -0.46 -0.6282 -0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E11 compound treatment 9.0136169E7 -6420000.0 -0.55 8.6246791E7 -8830000.0 -0.77 -0.9383 -0.9868 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E12 compound treatment 2.0754804E7 -7.58E7 -6.55 2.146133E7 -7.36E7 -6.44 -9.185 -1.0 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E13 compound treatment 9.2959666E7 -3600000.0 -0.31 9.1485007E7 -3590000.0 -0.31 -0.4417 -1.0 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E14 compound treatment 8.7807808E7 -8750000.0 -0.76 8.8603136E7 -6470000.0 -0.57 -0.9347 -0.9899 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E15 compound treatment 9.4684982E7 -1870000.0 -0.16 9.4352001E7 -722000.0 -0.06 -0.1589 -0.916 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E16 compound treatment 7.2452741E7 -2.41E7 -2.08 7.8490184E7 -1.66E7 -1.45 -2.4983 -0.9844 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E17 mock treatment 1.02967288E8 6410000.0 0.55 1.02346082E8 7270000.0 0.64 0.8416 0.9976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E18 mock treatment 1.04610994E8 8060000.0 0.7 1.02311508E8 7240000.0 0.63 0.9399 0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E19 compound treatment 8.4966764E7 -1.16E7 -1.0 8.743347E7 -7640000.0 -0.67 -1.1806 -0.9808 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E20 compound treatment 7.5630102E7 -2.09E7 -1.81 7.8433106E7 -1.66E7 -1.46 -2.3078 -0.9943 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E21 compound treatment 8.5644286E7 -1.09E7 -0.94 8.7665693E7 -7410000.0 -0.65 -1.1249 -0.9833 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E22 compound treatment 7.2275034E7 -2.43E7 -2.1 7.7595499E7 -1.75E7 -1.53 -2.5646 -0.988 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E23 compound treatment 1.08626516E8 1.21E7 1.04 1.04656423E8 9580000.0 0.84 1.3302 0.9942 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 E24 compound treatment 7.9494115E7 -1.71E7 -1.47 6.6469513E7 -2.86E7 -2.5 -2.8122 -0.9681 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F01 mock treatment 1.01414742E8 4860000.0 0.42 1.01504809E8 6430000.0 0.56 0.6947 0.9896 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F02 mock treatment 9.8026395E7 1470000.0 0.13 9.4725231E7 -349000.0 -0.03 0.0682 0.5224 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F03 compound treatment 8.6966884E7 -9590000.0 -0.83 8.4986414E7 -1.01E7 -0.88 -1.2099 -0.9995 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F04 compound treatment 9.9790186E7 3230000.0 0.28 9.6601949E7 1530000.0 0.13 0.2921 0.9431 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F05 compound treatment 8.6785659E7 -9770000.0 -0.84 9.0162262E7 -4910000.0 -0.43 -0.9007 -0.951 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F06 compound treatment 5.3765985E7 -4.28E7 -3.7 6.3263591E7 -3.18E7 -2.78 -4.5819 -0.9902 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F07 compound treatment 8.1009149E7 -1.55E7 -1.34 8.4982221E7 -1.01E7 -0.88 -1.574 -0.9793 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F08 compound treatment 9.294006E7 -3620000.0 -0.31 9.28986E7 -2180000.0 -0.19 -0.3554 -0.9718 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F09 mock treatment 9.5593427E7 -962000.0 -0.08 9.5532167E7 458000.0 0.04 -0.0304 -0.3295 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F10 mock treatment 9.0381534E7 -6170000.0 -0.53 9.0856001E7 -4220000.0 -0.37 -0.6381 -0.9839 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F11 compound treatment 7.6963375E7 -1.96E7 -1.69 7.9566233E7 -1.55E7 -1.36 -2.1563 -0.994 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F12 compound treatment 3.0492752E7 -6.61E7 -5.71 2.6368804E7 -6.87E7 -6.01 -8.2865 -0.9997 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F13 compound treatment 8.9231767E7 -7320000.0 -0.63 8.7072888E7 -8000000.0 -0.7 -0.9424 -0.9987 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F14 compound treatment 9.434169E7 -2210000.0 -0.19 9.2747365E7 -2330000.0 -0.2 -0.2792 -0.9995 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F15 compound treatment 8.6143173E7 -1.04E7 -0.9 8.6529625E7 -8540000.0 -0.75 -1.1647 -0.9958 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F16 compound treatment 9.3964468E7 -2590000.0 -0.22 9.4361784E7 -712000.0 -0.06 -0.2023 -0.8709 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F17 mock treatment 1.02735088E8 6180000.0 0.53 1.02417903E8 7340000.0 0.64 0.8319 0.9957 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F18 mock treatment 1.02025608E8 5470000.0 0.47 1.01859506E8 6790000.0 0.59 0.754 0.9936 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F19 compound treatment 9.4631145E7 -1920000.0 -0.17 9.5730787E7 657000.0 0.06 -0.0769 -0.4371 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F20 compound treatment 9.2799974E7 -3760000.0 -0.32 9.2780389E7 -2290000.0 -0.2 -0.3713 -0.9734 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F21 compound treatment 9.0088399E7 -6470000.0 -0.56 8.9667585E7 -5410000.0 -0.47 -0.7296 -0.9966 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F22 compound treatment 9.5641668E7 -914000.0 -0.08 9.4511195E7 -563000.0 -0.05 -0.0906 -0.9742 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F23 compound treatment 3.75997E7 -5.9E7 -5.09 4.8047004E7 -4.7E7 -4.12 -6.5109 -0.9944 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 F24 compound treatment 9.3885227E7 -2670000.0 -0.23 9.2447262E7 -2630000.0 -0.23 -0.3256 -1.0 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G01 compound treatment 1.10303308E8 1.37E7 1.19 9.7705554E7 2630000.0 0.23 1.0025 0.8288 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G02 compound treatment 9.7541859E7 986000.0 0.09 9.2611333E7 -2460000.0 -0.22 -0.0922 -0.3977 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G03 mock treatment 1.04240167E8 7680000.0 0.66 1.01582613E8 6510000.0 0.57 0.8721 0.9971 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G04 mock treatment 9.9221611E7 2670000.0 0.23 9.4949227E7 -125000.0 -0.01 0.1551 0.6729 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G05 compound treatment 9.8620981E7 2070000.0 0.18 9.8938337E7 3860000.0 0.34 0.3653 0.9553 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G06 compound treatment 9.9790512E7 3230000.0 0.28 9.5581149E7 507000.0 0.04 0.229 0.8093 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G07 compound treatment 5.9974756E7 -3.66E7 -3.16 6.0299996E7 -3.48E7 -3.04 -4.3861 -0.9998 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G08 compound treatment 9.4250774E7 -2310000.0 -0.2 9.0068227E7 -5010000.0 -0.44 -0.4505 -0.9363 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G09 compound treatment 9.0748322E7 -5810000.0 -0.5 9.2503161E7 -2570000.0 -0.22 -0.5138 -0.9346 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G10 compound treatment 9.3581928E7 -2970000.0 -0.26 9.1841505E7 -3230000.0 -0.28 -0.3817 -0.9988 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G11 compound treatment 9.1525757E7 -5030000.0 -0.43 9.1469526E7 -3600000.0 -0.32 -0.5303 -0.9876 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G12 compound treatment 9.2465805E7 -4090000.0 -0.35 8.9017713E7 -6060000.0 -0.53 -0.6246 -0.9806 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G13 compound treatment 9.5480615E7 -1080000.0 -0.09 9.3977048E7 -1100000.0 -0.1 -0.1335 -0.9999 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G14 compound treatment 7.3502239E7 -2.31E7 -1.99 7.6296899E7 -1.88E7 -1.64 -2.57 -0.9955 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G15 compound treatment 9.5750047E7 -806000.0 -0.07 9.2246504E7 -2830000.0 -0.25 -0.2242 -0.8721 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G16 compound treatment 9.7799426E7 1240000.0 0.11 9.2353938E7 -2720000.0 -0.24 -0.0924 -0.3537 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G17 compound treatment 1.01462944E8 4910000.0 0.42 9.5722721E7 649000.0 0.06 0.3399 0.7947 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G18 compound treatment 9.2256885E7 -4300000.0 -0.37 9.1495617E7 -3580000.0 -0.31 -0.484 -0.9964 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G19 mock treatment 1.02707228E8 6150000.0 0.53 9.5573633E7 500000.0 0.04 0.4066 0.7627 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G20 mock treatment 1.01222505E8 4670000.0 0.4 9.8920505E7 3850000.0 0.34 0.5231 0.996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G21 compound treatment 1.00832822E8 4280000.0 0.37 9.6063674E7 990000.0 0.09 0.3225 0.8499 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G22 compound treatment 9.868621E7 2130000.0 0.18 1.00229615E8 5160000.0 0.45 0.4492 0.9218 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G23 compound treatment 1.1005559E8 1.35E7 1.17 1.0441611E8 9340000.0 0.82 1.4026 0.9849 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 G24 compound treatment 7.6987906E7 -1.96E7 -1.69 7.3717359E7 -2.14E7 -1.87 -2.5167 -0.9987 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H01 compound treatment 1.11408031E8 1.49E7 1.28 1.0425934E8 9190000.0 0.8 1.4755 0.9747 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H02 compound treatment 1.04268054E8 7710000.0 0.67 9.7156011E7 2080000.0 0.18 0.5999 0.8686 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H03 mock treatment 9.8096502E7 1540000.0 0.13 1.02445711E8 7370000.0 0.65 0.5503 0.8354 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H04 mock treatment 9.5554735E7 -1000000.0 -0.09 9.5764578E7 691000.0 0.06 -0.0184 -0.1743 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H05 compound treatment 8.010628E7 -1.64E7 -1.42 8.0110095E7 -1.5E7 -1.31 -1.9307 -0.9992 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H06 compound treatment 9.3167279E7 -3390000.0 -0.29 8.7579687E7 -7490000.0 -0.66 -0.6707 -0.9339 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H07 compound treatment 9.8756793E7 2200000.0 0.19 9.8860345E7 3790000.0 0.33 0.3688 0.9652 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H08 compound treatment 8.7301822E7 -9250000.0 -0.8 8.3986576E7 -1.11E7 -0.97 -1.2513 -0.9954 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H09 compound treatment 2.0821307E7 -7.57E7 -6.54 2.0577523E7 -7.45E7 -6.52 -9.2356 -1.0 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H10 compound treatment 8.5685175E7 -1.09E7 -0.94 8.2374739E7 -1.27E7 -1.11 -1.4498 -0.9965 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H11 compound treatment 8.4959872E7 -1.16E7 -1.0 8.2360801E7 -1.27E7 -1.11 -1.495 -0.9986 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H12 compound treatment 9.2468417E7 -4090000.0 -0.35 9.21368E7 -2940000.0 -0.26 -0.4314 -0.9878 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H13 compound treatment 8.9460756E7 -7100000.0 -0.61 9.0860987E7 -4210000.0 -0.37 -0.694 -0.9704 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H14 compound treatment 8.9363971E7 -7190000.0 -0.62 9.0775481E7 -4300000.0 -0.38 -0.7052 -0.9711 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H15 compound treatment 9.7425146E7 869000.0 0.08 9.7357383E7 2280000.0 0.2 0.1944 0.9106 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H16 compound treatment 9.1845523E7 -4710000.0 -0.41 8.7681168E7 -7390000.0 -0.65 -0.7452 -0.975 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H17 compound treatment 1.01829156E8 5270000.0 0.46 9.9353438E7 4280000.0 0.37 0.5869 0.9953 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H18 compound treatment 9.8913358E7 2360000.0 0.2 9.0711986E7 -4360000.0 -0.38 -0.1259 -0.2911 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H19 mock treatment 1.01041942E8 4490000.0 0.39 1.00401475E8 5330000.0 0.47 0.6037 0.9958 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H20 mock treatment 9.9096186E7 2540000.0 0.22 9.4803931E7 -270000.0 -0.02 0.1385 0.6274 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H21 compound treatment 1.02572459E8 6020000.0 0.52 1.04692544E8 9620000.0 0.84 0.9627 0.9731 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H22 compound treatment 1.03012182E8 6460000.0 0.56 9.2281265E7 -2790000.0 -0.24 0.2215 0.3638 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H23 compound treatment 1.12050183E8 1.55E7 1.34 1.04284336E8 9210000.0 0.81 1.5163 0.9706 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 H24 compound treatment 1.07737926E8 1.12E7 0.97 1.03758284E8 8680000.0 0.76 1.2204 0.993 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I01 compound treatment 1.0418557E8 7630000.0 0.66 9.7495277E7 2420000.0 0.21 0.6158 0.8896 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I02 compound treatment 9.5812656E7 -743000.0 -0.06 9.609151E7 1020000.0 0.09 0.0176 0.1602 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I03 compound treatment 9.7887456E7 1330000.0 0.12 9.8332414E7 3260000.0 0.29 0.283 0.9203 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I04 compound treatment 1.00255039E8 3700000.0 0.32 9.9955622E7 4880000.0 0.43 0.528 0.9898 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I05 mock treatment 9.7871747E7 1320000.0 0.11 9.9096969E7 4020000.0 0.35 0.3293 0.8901 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I06 mock treatment 9.6299521E7 -256000.0 -0.02 9.2273962E7 -2800000.0 -0.25 -0.1889 -0.7679 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I07 compound treatment 9.6909608E7 354000.0 0.03 9.7256081E7 2180000.0 0.19 0.1567 0.81 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I08 compound treatment 8.6762764E7 -9790000.0 -0.85 8.4510764E7 -1.06E7 -0.92 -1.2518 -0.999 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I09 compound treatment 9.5733876E7 -822000.0 -0.07 9.5448314E7 374000.0 0.03 -0.027 -0.3456 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I10 compound treatment 4.2081432E7 -5.45E7 -4.71 3.6787145E7 -5.83E7 -5.1 -6.934 -0.9992 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I11 compound treatment 9.2853551E7 -3700000.0 -0.32 9.4775694E7 -298000.0 -0.03 -0.2446 -0.7623 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I12 compound treatment 4.5661731E7 -5.09E7 -4.4 3.5916815E7 -5.92E7 -5.18 -6.7692 -0.9967 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I13 compound treatment 9.383553E7 -2720000.0 -0.23 9.2767632E7 -2310000.0 -0.2 -0.3089 -0.9971 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I14 compound treatment 9.2131102E7 -4420000.0 -0.38 9.2274825E7 -2800000.0 -0.24 -0.4434 -0.9769 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I15 compound treatment 9.6221386E7 -334000.0 -0.03 9.4584311E7 -490000.0 -0.04 -0.0507 -0.9816 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I16 compound treatment 9.3641335E7 -2910000.0 -0.25 9.3926404E7 -1150000.0 -0.1 -0.249 -0.9188 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I17 compound treatment 8.7868128E7 -8690000.0 -0.75 8.7368284E7 -7710000.0 -0.67 -1.0074 -0.9986 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I18 compound treatment 9.6037815E7 -518000.0 -0.04 9.6036419E7 963000.0 0.08 0.0279 0.2929 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I19 compound treatment 9.6493394E7 -62400.0 -0.01 9.4701753E7 -372000.0 -0.03 -0.0268 -0.8131 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I20 compound treatment 1.01225286E8 4670000.0 0.4 1.00142357E8 5070000.0 0.44 0.5988 0.9989 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I21 mock treatment 9.8351396E7 1800000.0 0.16 1.00441929E8 5370000.0 0.47 0.4419 0.8931 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I22 mock treatment 9.9558833E7 3000000.0 0.26 9.7038829E7 1970000.0 0.17 0.305 0.9801 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I23 compound treatment 1.00462964E8 3910000.0 0.34 9.8752538E7 3680000.0 0.32 0.4663 0.9997 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 I24 compound treatment 8.5765264E7 -1.08E7 -0.93 7.9272657E7 -1.58E7 -1.38 -1.6369 -0.9816 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J01 compound treatment 9.616166E7 -394000.0 -0.03 8.7765748E7 -7310000.0 -0.64 -0.4763 -0.7437 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J02 compound treatment 9.0709164E7 -5850000.0 -0.5 8.615861E7 -8920000.0 -0.78 -0.9088 -0.9778 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J03 compound treatment 1.02411757E8 5860000.0 0.51 1.02760856E8 7690000.0 0.67 0.8334 0.9901 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J04 compound treatment 9.6036761E7 -519000.0 -0.04 9.4788031E7 -286000.0 -0.03 -0.0494 -0.962 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J05 mock treatment 9.9285892E7 2730000.0 0.24 9.871258E7 3640000.0 0.32 0.3919 0.9891 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J06 mock treatment 9.0090506E7 -6470000.0 -0.56 9.2756879E7 -2320000.0 -0.2 -0.5382 -0.906 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J07 compound treatment 1.01882319E8 5330000.0 0.46 1.02614373E8 7540000.0 0.66 0.792 0.9844 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J08 compound treatment 9.2759237E7 -3800000.0 -0.33 9.1445383E7 -3630000.0 -0.32 -0.4564 -0.9999 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J09 compound treatment 7.8993472E7 -1.76E7 -1.52 7.9253441E7 -1.58E7 -1.38 -2.0516 -0.999 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J10 compound treatment 8.8158786E7 -8400000.0 -0.73 8.8982969E7 -6090000.0 -0.53 -0.8898 -0.9885 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J11 compound treatment 9.2661547E7 -3890000.0 -0.34 9.3521657E7 -1550000.0 -0.14 -0.3339 -0.9205 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J12 compound treatment 6.5098847E7 -3.15E7 -2.72 6.6059904E7 -2.9E7 -2.54 -3.7167 -0.9994 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J13 compound treatment 9.4213543E7 -2340000.0 -0.2 8.8473155E7 -6600000.0 -0.58 -0.5515 -0.9011 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J14 compound treatment 9.0185143E7 -6370000.0 -0.55 8.9721142E7 -5350000.0 -0.47 -0.7203 -0.9968 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J15 compound treatment 1.02976916E8 6420000.0 0.55 1.00034001E8 4960000.0 0.43 0.6991 0.9927 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J16 compound treatment 7.4744961E7 -2.18E7 -1.88 6.9457908E7 -2.56E7 -2.24 -2.9173 -0.9963 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J17 compound treatment 5.5446217E7 -4.11E7 -3.55 4.7617788E7 -4.75E7 -4.15 -5.4475 -0.997 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J18 compound treatment 9.5562221E7 -994000.0 -0.09 9.0425107E7 -4650000.0 -0.41 -0.3484 -0.8378 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J19 compound treatment 9.9784491E7 3230000.0 0.28 9.9561375E7 4490000.0 0.39 0.4749 0.9859 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J20 compound treatment 9.1522724E7 -5030000.0 -0.43 8.9744656E7 -5330000.0 -0.47 -0.6372 -0.9994 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J21 mock treatment 1.01783344E8 5230000.0 0.45 1.02023909E8 6950000.0 0.61 0.7494 0.9892 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J22 mock treatment 9.6722583E7 167000.0 0.01 9.3145191E7 -1930000.0 -0.17 -0.1092 -0.6444 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J23 compound treatment 9.9188157E7 2630000.0 0.23 9.8023682E7 2950000.0 0.26 0.3433 0.998 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 J24 compound treatment 1.05458678E8 8900000.0 0.77 9.8426116E7 3350000.0 0.29 0.7512 0.9127 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K01 compound treatment 9.4076585E7 -2480000.0 -0.21 1.05163199E8 1.01E7 0.88 0.473 0.5205 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K02 compound treatment 1.02952894E8 6400000.0 0.55 9.8604679E7 3530000.0 0.31 0.6092 0.9623 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K03 compound treatment 9.7126175E7 570000.0 0.05 9.6070577E7 997000.0 0.09 0.0965 0.9634 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K04 compound treatment 9.6976066E7 420000.0 0.04 9.8739203E7 3670000.0 0.32 0.2525 0.7821 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K05 compound treatment 1.01377093E8 4820000.0 0.42 1.00047107E8 4970000.0 0.44 0.6022 0.9998 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K06 compound treatment 8.4546232E7 -1.2E7 -1.04 9.2896091E7 -2180000.0 -0.19 -0.8682 -0.8232 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K07 mock treatment 9.9062144E7 2510000.0 0.22 9.3323804E7 -1750000.0 -0.15 0.0448 0.1689 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K08 mock treatment 9.5466601E7 -1090000.0 -0.09 9.1975745E7 -3100000.0 -0.27 -0.2582 -0.8998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K09 compound treatment 7.8275857E7 -1.83E7 -1.58 8.2272869E7 -1.28E7 -1.12 -1.9086 -0.9859 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K10 compound treatment 3.4347854E7 -6.22E7 -5.37 2.505263E7 -7.0E7 -6.13 -8.1325 -0.9979 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K11 compound treatment 9.8204495E7 1650000.0 0.14 9.7250288E7 2180000.0 0.19 0.2354 0.9897 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K12 compound treatment 8.8008711E7 -8550000.0 -0.74 8.691334E7 -8160000.0 -0.71 -1.027 -0.9999 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K13 compound treatment 8.6411514E7 -1.01E7 -0.88 8.7582184E7 -7490000.0 -0.66 -1.0832 -0.9898 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K14 compound treatment 8.6672229E7 -9880000.0 -0.85 8.5227789E7 -9850000.0 -0.86 -1.2129 -1.0 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K15 mock treatment 9.7572727E7 1020000.0 0.09 9.1501487E7 -3570000.0 -0.31 -0.159 -0.4895 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K16 mock treatment 9.5496469E7 -1060000.0 -0.09 9.4772108E7 -302000.0 -0.03 -0.0834 -0.8755 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K17 compound treatment 9.6894836E7 339000.0 0.03 9.5534987E7 461000.0 0.04 0.0492 0.9876 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K18 compound treatment 9.7756208E7 1200000.0 0.1 9.0895244E7 -4180000.0 -0.37 -0.1853 -0.4874 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K19 compound treatment 9.7807279E7 1250000.0 0.11 9.5297049E7 223000.0 0.02 0.0902 0.8216 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K20 compound treatment 9.4745626E7 -1810000.0 -0.16 9.2482438E7 -2590000.0 -0.23 -0.2709 -0.9835 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K21 compound treatment 1.01181344E8 4630000.0 0.4 9.890052E7 3830000.0 0.33 0.5193 0.9962 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K22 compound treatment 9.6758234E7 202000.0 0.02 9.333914E7 -1730000.0 -0.15 -0.095 -0.6216 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K23 mock treatment 1.01062773E8 4510000.0 0.39 9.8813543E7 3740000.0 0.33 0.5067 0.9963 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 K24 mock treatment 1.04721157E8 8170000.0 0.71 1.02492552E8 7420000.0 0.65 0.9578 0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L01 compound treatment 9.2753538E7 -3800000.0 -0.33 1.03716524E8 8640000.0 0.76 0.3026 0.367 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L02 compound treatment 9.852919E7 1970000.0 0.17 9.7888632E7 2810000.0 0.25 0.2947 0.9838 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L03 compound treatment 2.0880823E7 -7.57E7 -6.54 2.0475267E7 -7.46E7 -6.53 -9.2383 -1.0 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L04 compound treatment 1.0027568E8 3720000.0 0.32 9.7348269E7 2270000.0 0.2 0.3679 0.9735 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L05 compound treatment 8.7540937E7 -9010000.0 -0.78 8.6972362E7 -8100000.0 -0.71 -1.0519 -0.9989 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L06 compound treatment 8.8309388E7 -8250000.0 -0.71 9.4780837E7 -293000.0 -0.03 -0.5218 -0.7321 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L07 mock treatment 1.00860839E8 4310000.0 0.37 9.9526998E7 4450000.0 0.39 0.5385 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L08 mock treatment 9.5990877E7 -565000.0 -0.05 9.3607419E7 -1470000.0 -0.13 -0.1252 -0.9122 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L09 compound treatment 9.7273597E7 718000.0 0.06 9.1757693E7 -3320000.0 -0.29 -0.1614 -0.5438 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L10 compound treatment 9.5672978E7 -883000.0 -0.08 9.2454567E7 -2620000.0 -0.23 -0.216 -0.8941 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L11 compound treatment 9.647795E7 -77800.0 -0.01 9.1552475E7 -3520000.0 -0.31 -0.2227 -0.7224 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L12 compound treatment 9.1942722E7 -4610000.0 -0.4 8.972238E7 -5350000.0 -0.47 -0.6129 -0.9968 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L13 compound treatment 6.9979946E7 -2.66E7 -2.3 7.1080421E7 -2.4E7 -2.1 -3.1079 -0.999 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L14 compound treatment 8.8935596E7 -7620000.0 -0.66 8.7485681E7 -7590000.0 -0.66 -0.935 -1.0 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L15 mock treatment 9.7649121E7 1090000.0 0.09 9.5316055E7 242000.0 0.02 0.0818 0.8448 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L16 mock treatment 9.4180195E7 -2380000.0 -0.21 9.215978E7 -2910000.0 -0.26 -0.3254 -0.9942 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L17 compound treatment 1.03948706E8 7390000.0 0.64 9.9697548E7 4620000.0 0.4 0.7377 0.9758 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L18 compound treatment 9.5099224E7 -1460000.0 -0.13 8.8776876E7 -6300000.0 -0.55 -0.4786 -0.8467 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L19 compound treatment 9.5359454E7 -1200000.0 -0.1 9.5496575E7 423000.0 0.04 -0.0469 -0.4274 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L20 compound treatment 9.5418213E7 -1140000.0 -0.1 9.055289E7 -4520000.0 -0.4 -0.3493 -0.8567 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L21 compound treatment 9.7184651E7 629000.0 0.05 1.04221033E8 9150000.0 0.8 0.6045 0.7534 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L22 compound treatment 1.02801979E8 6250000.0 0.54 1.00136524E8 5060000.0 0.44 0.6948 0.9952 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L23 mock treatment 1.06502532E8 9950000.0 0.86 1.00776001E8 5700000.0 0.5 0.9604 0.9666 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 L24 mock treatment 1.07186842E8 1.06E7 0.92 9.9640217E7 4570000.0 0.4 0.9319 0.9305 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M01 compound treatment 9.8670856E7 2120000.0 0.18 9.7924752E7 2850000.0 0.25 0.3056 0.9883 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M02 compound treatment 1.0913247E8 1.26E7 1.09 9.7724099E7 2650000.0 0.23 0.9321 0.8392 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M03 compound treatment 8.7828163E7 -8730000.0 -0.75 9.7517379E7 2440000.0 0.21 -0.3818 -0.4873 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M04 compound treatment 9.5086751E7 -1470000.0 -0.13 8.2252849E7 -1.28E7 -1.12 -0.8831 -0.7821 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M05 compound treatment 1.07153374E8 1.06E7 0.92 1.03326776E8 8250000.0 0.72 1.158 0.9931 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M06 compound treatment 6.9178567E7 -2.74E7 -2.36 7.9851307E7 -1.52E7 -1.33 -2.6141 -0.9631 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M07 compound treatment 5.234165E7 -4.42E7 -3.82 5.9829714E7 -3.52E7 -3.08 -4.8814 -0.9944 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M08 compound treatment 7.721627E7 -1.93E7 -1.67 7.4792363E7 -2.03E7 -1.77 -2.4363 -0.9995 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M09 mock treatment 9.9075595E7 2520000.0 0.22 9.1774216E7 -3300000.0 -0.29 -0.0503 -0.1391 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M10 mock treatment 8.6131758E7 -1.04E7 -0.9 8.3237044E7 -1.18E7 -1.04 -1.3692 -0.9976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M11 compound treatment 7.6169642E7 -2.04E7 -1.76 8.2889477E7 -1.22E7 -1.07 -1.9991 -0.9711 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M12 compound treatment 4.4640951E7 -5.19E7 -4.48 4.6794123E7 -4.83E7 -4.23 -6.1584 -0.9996 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M13 mock treatment 8.7041472E7 -9510000.0 -0.82 9.4302875E7 -771000.0 -0.07 -0.6288 -0.7626 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M14 mock treatment 9.2413799E7 -4140000.0 -0.36 9.0431476E7 -4640000.0 -0.41 -0.5403 -0.998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M15 compound treatment 7.3563893E7 -2.3E7 -1.99 6.5283477E7 -2.98E7 -2.61 -3.2478 -0.991 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M16 compound treatment 8.6131431E7 -1.04E7 -0.9 8.1986568E7 -1.31E7 -1.15 -1.4466 -0.9929 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M17 compound treatment 6.4439021E7 -3.21E7 -2.77 8.3788057E7 -1.13E7 -0.99 -2.6599 -0.9033 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M18 compound treatment 9.8106401E7 1550000.0 0.13 8.7980021E7 -7090000.0 -0.62 -0.3443 -0.5421 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M19 compound treatment 2.052057E7 -7.6E7 -6.57 2.0360767E7 -7.47E7 -6.54 -9.2674 -1.0 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M20 compound treatment 9.9568953E7 3010000.0 0.26 9.4069392E7 -1000000.0 -0.09 0.1219 0.4436 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M21 compound treatment 1.0949854E8 1.29E7 1.12 1.04746149E8 9670000.0 0.85 1.389 0.9906 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M22 compound treatment 8.2723511E7 -1.38E7 -1.19 7.3726994E7 -2.13E7 -1.87 -2.1658 -0.9767 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M23 compound treatment 1.04512814E8 7960000.0 0.69 1.0539598E8 1.03E7 0.9 1.1248 0.9909 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 M24 compound treatment 8.8705445E7 -7850000.0 -0.68 8.9925909E7 -5150000.0 -0.45 -0.798 -0.9803 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N01 compound treatment 1.14895885E8 1.83E7 1.58 1.03123928E8 8050000.0 0.7 1.6183 0.9334 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N02 compound treatment 1.04680188E8 8120000.0 0.7 1.00209276E8 5140000.0 0.45 0.814 0.9768 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N03 compound treatment 9.6023359E7 -532000.0 -0.05 9.427571E7 -798000.0 -0.07 -0.0819 -0.9794 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N04 compound treatment 1.04291302E8 7740000.0 0.67 9.9010832E7 3940000.0 0.34 0.7161 0.9526 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N05 compound treatment 9.746234E7 907000.0 0.08 9.4266901E7 -807000.0 -0.07 0.0054 0.0515 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N06 compound treatment 8.6275061E7 -1.03E7 -0.89 8.5210526E7 -9860000.0 -0.86 -1.2383 -0.9999 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N07 compound treatment 1.07633642E8 1.11E7 0.96 9.9851586E7 4780000.0 0.42 0.9722 0.9311 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N08 compound treatment 8.8080215E7 -8480000.0 -0.73 8.9579253E7 -5490000.0 -0.48 -0.8577 -0.9792 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N09 mock treatment 9.3891449E7 -2660000.0 -0.23 8.3624796E7 -1.14E7 -1.0 -0.8712 -0.8474 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N10 mock treatment 9.4389093E7 -2170000.0 -0.19 8.5554151E7 -9520000.0 -0.83 -0.7214 -0.8449 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N11 compound treatment 9.5450061E7 -1110000.0 -0.1 9.4884306E7 -190000.0 -0.02 -0.0793 -0.8177 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N12 compound treatment 8.9534993E7 -7020000.0 -0.61 7.9643908E7 -1.54E7 -1.35 -1.3837 -0.9347 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N13 mock treatment 9.6728281E7 173000.0 0.01 9.2438198E7 -2640000.0 -0.23 -0.1526 -0.6601 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N14 mock treatment 8.7923502E7 -8630000.0 -0.75 8.8221218E7 -6850000.0 -0.6 -0.9513 -0.9942 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N15 compound treatment 8.5457239E7 -1.11E7 -0.96 8.1139178E7 -1.39E7 -1.22 -1.5402 -0.9929 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N16 compound treatment 7.5063125E7 -2.15E7 -1.86 7.6232879E7 -1.88E7 -1.65 -2.4786 -0.9983 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N17 compound treatment 9.2985933E7 -3570000.0 -0.31 9.4903206E7 -171000.0 -0.01 -0.2286 -0.7405 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N18 compound treatment 9.8160911E7 1610000.0 0.14 8.6717834E7 -8360000.0 -0.73 -0.4191 -0.563 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N19 compound treatment 6.8383569E7 -2.82E7 -2.43 7.2874025E7 -2.22E7 -1.94 -3.0944 -0.9938 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N20 compound treatment 8.9839823E7 -6720000.0 -0.58 9.1894261E7 -3180000.0 -0.28 -0.6069 -0.9434 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N21 compound treatment 1.0830974E8 1.18E7 1.02 9.2480206E7 -2590000.0 -0.23 0.5574 0.5358 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N22 compound treatment 9.8314734E7 1760000.0 0.15 9.6914826E7 1840000.0 0.16 0.2214 0.9996 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N23 compound treatment 1.01846489E8 5290000.0 0.46 1.02400672E8 7330000.0 0.64 0.7765 0.9862 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 N24 compound treatment 1.07622755E8 1.11E7 0.96 9.7156862E7 2080000.0 0.18 0.8048 0.8271 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O01 compound treatment 1.07491924E8 1.09E7 0.94 1.04973436E8 9900000.0 0.87 1.2805 0.9991 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O02 compound treatment 9.7878095E7 1320000.0 0.11 9.1857231E7 -3220000.0 -0.28 -0.1183 -0.3894 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O03 compound treatment 1.07888948E8 1.13E7 0.98 1.05453779E8 1.04E7 0.91 1.3345 0.9993 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O04 compound treatment 7.4803311E7 -2.18E7 -1.88 7.5521117E7 -1.96E7 -1.71 -2.5385 -0.9989 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O05 compound treatment 1.034379E8 6880000.0 0.59 1.03613426E8 8540000.0 0.75 0.9488 0.9936 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O06 compound treatment 1.01302366E8 4750000.0 0.41 9.54624E7 389000.0 0.03 0.3139 0.7631 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O07 compound treatment 9.1947254E7 -4610000.0 -0.4 9.1546879E7 -3530000.0 -0.31 -0.4997 -0.9921 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O08 compound treatment 9.6632728E7 77000.0 0.01 9.1353846E7 -3720000.0 -0.33 -0.2255 -0.6925 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O09 compound treatment 8.850127E7 -8050000.0 -0.7 8.6582146E7 -8490000.0 -0.74 -1.0174 -0.9995 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O10 compound treatment 9.0020247E7 -6540000.0 -0.56 8.974256E7 -5330000.0 -0.47 -0.7291 -0.9955 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O11 mock treatment 9.1853278E7 -4700000.0 -0.41 9.0496759E7 -4580000.0 -0.4 -0.5705 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O12 mock treatment 8.7076012E7 -9480000.0 -0.82 8.9151882E7 -5920000.0 -0.52 -0.9454 -0.9757 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O13 compound treatment 9.4163379E7 -2390000.0 -0.21 8.0169578E7 -1.49E7 -1.3 -1.0685 -0.809 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O14 compound treatment 3.7934323E7 -5.86E7 -5.06 4.379105E7 -5.13E7 -4.49 -6.7539 -0.9982 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O15 compound treatment 8.8303639E7 -8250000.0 -0.71 8.8760051E7 -6310000.0 -0.55 -0.8947 -0.9921 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O16 compound treatment 8.6363719E7 -1.02E7 -0.88 8.0580276E7 -1.45E7 -1.27 -1.5194 -0.9841 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O17 compound treatment 1.00242305E8 3690000.0 0.32 9.8355349E7 3280000.0 0.29 0.4282 0.9987 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O18 compound treatment 9.8196126E7 1640000.0 0.14 9.1207277E7 -3870000.0 -0.34 -0.1391 -0.3792 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O19 compound treatment 9.6117378E7 -438000.0 -0.04 9.9016056E7 3940000.0 0.35 0.2172 0.6257 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O20 compound treatment 9.9158924E7 2600000.0 0.22 9.6375528E7 1300000.0 0.11 0.2395 0.9504 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O21 compound treatment 1.07176998E8 1.06E7 0.92 1.0227599E8 7200000.0 0.63 1.0944 0.9832 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O22 compound treatment 9.3852095E7 -2700000.0 -0.23 8.9786034E7 -5290000.0 -0.46 -0.4924 -0.9498 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O23 compound treatment 2.219313E7 -7.44E7 -6.42 2.3576124E7 -7.15E7 -6.26 -8.9662 -0.9999 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 O24 compound treatment 1.06165118E8 9610000.0 0.83 1.0534366E8 1.03E7 0.9 1.2224 0.9992 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P01 compound treatment 1.03124908E8 6570000.0 0.57 8.736144E7 -7710000.0 -0.67 -0.0761 -0.0863 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P02 compound treatment 1.02049695E8 5490000.0 0.47 9.6492469E7 1420000.0 0.12 0.4233 0.8631 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P03 compound treatment 9.8443474E7 1890000.0 0.16 9.8717504E7 3640000.0 0.32 0.3408 0.9515 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P04 compound treatment 9.9698985E7 3140000.0 0.27 9.4768611E7 -305000.0 -0.03 0.1731 0.6345 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P05 compound treatment 2.1241017E7 -7.53E7 -6.51 2.0558604E7 -7.45E7 -6.52 -9.2111 -1.0 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P06 compound treatment 9.9999967E7 3440000.0 0.3 9.2480422E7 -2590000.0 -0.23 0.0499 0.1333 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P07 compound treatment 9.8889233E7 2330000.0 0.2 9.5318392E7 245000.0 0.02 0.1576 0.7778 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P08 compound treatment 9.4048551E7 -2510000.0 -0.22 8.976097E7 -5310000.0 -0.46 -0.4819 -0.9395 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P09 compound treatment 9.5233262E7 -1320000.0 -0.11 9.3982477E7 -1090000.0 -0.1 -0.1483 -0.996 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P10 compound treatment 9.7869292E7 1310000.0 0.11 9.2895149E7 -2180000.0 -0.19 -0.0546 -0.2461 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P11 mock treatment 9.6733352E7 178000.0 0.02 9.520503E7 131000.0 0.01 0.019 0.9898 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P12 mock treatment 9.1869773E7 -4690000.0 -0.4 8.5765505E7 -9310000.0 -0.81 -0.8622 -0.9479 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P13 compound treatment 9.7503465E7 948000.0 0.08 7.8613539E7 -1.65E7 -1.44 -0.9608 -0.6659 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P14 compound treatment 9.2233967E7 -4320000.0 -0.37 8.9751403E7 -5320000.0 -0.47 -0.5933 -0.994 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P15 compound treatment 9.6496185E7 -59600.0 -0.01 9.6588594E7 1510000.0 0.13 0.0901 0.6791 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P16 compound treatment 8.0885754E7 -1.57E7 -1.35 7.7808813E7 -1.73E7 -1.51 -2.0255 -0.9985 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P17 compound treatment 1.06810075E8 1.03E7 0.89 1.01890316E8 6820000.0 0.6 1.0481 0.9815 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P18 compound treatment 7.0315854E7 -2.62E7 -2.27 6.6261518E7 -2.88E7 -2.52 -3.3856 -0.9986 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P19 compound treatment 1.08508975E8 1.2E7 1.03 9.899549E7 3920000.0 0.34 0.9727 0.8941 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P20 compound treatment 9.6800389E7 245000.0 0.02 9.2118382E7 -2960000.0 -0.26 -0.168 -0.6472 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P21 compound treatment 1.05156033E8 8600000.0 0.74 1.00107263E8 5030000.0 0.44 0.8367 0.9689 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P22 compound treatment 1.07156466E8 1.06E7 0.92 9.9983318E7 4910000.0 0.43 0.9513 0.9405 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P23 compound treatment 1.0810652E8 1.16E7 1.0 1.03534665E8 8460000.0 0.74 1.229 0.9892 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2097 P24 compound treatment 1.08498251E8 1.19E7 1.03 1.01681711E8 6610000.0 0.58 1.1383 0.9626 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A01 compound treatment 1.14772065E8 1.83E7 1.58 1.09523144E8 1.28E7 1.12 1.9098 0.9858 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A02 compound treatment 1.09266155E8 1.28E7 1.11 1.00539459E8 3810000.0 0.33 1.0176 0.8814 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A03 compound treatment 1.05648623E8 9180000.0 0.79 1.02130743E8 5410000.0 0.47 0.8952 0.9696 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A04 compound treatment 9.6894226E7 425000.0 0.04 9.3094533E7 -3630000.0 -0.32 -0.1987 -0.6214 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A05 compound treatment 7.5092533E7 -2.14E7 -1.85 7.5588327E7 -2.11E7 -1.85 -2.6136 -1.0 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A06 compound treatment 9.8690147E7 2220000.0 0.19 9.5188584E7 -1540000.0 -0.13 0.0406 0.1732 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A07 compound treatment 9.8840657E7 2370000.0 0.2 9.4585773E7 -2140000.0 -0.19 0.0124 0.0449 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A08 compound treatment 9.0226646E7 -6240000.0 -0.54 9.6645311E7 -79400.0 -0.01 -0.3862 -0.7162 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A09 compound treatment 9.5977867E7 -492000.0 -0.04 9.6844859E7 120000.0 0.01 -0.0226 -0.5164 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A10 compound treatment 9.5911005E7 -559000.0 -0.05 9.7297274E7 573000.0 0.05 0.0013 0.0189 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A11 compound treatment 7.5339931E7 -2.11E7 -1.83 7.6618078E7 -2.01E7 -1.76 -2.5348 -0.9998 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A12 compound treatment 1.01562676E8 5090000.0 0.44 1.02731525E8 6010000.0 0.53 0.6828 0.9961 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A13 mock treatment 9.7182076E7 712000.0 0.06 1.00722259E8 4000000.0 0.35 0.2909 0.8189 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A14 mock treatment 9.4292952E7 -2180000.0 -0.19 9.8163303E7 1440000.0 0.13 -0.0439 -0.1941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A15 compound treatment 8.8834376E7 -7640000.0 -0.66 9.1585155E7 -5140000.0 -0.45 -0.7844 -0.9826 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A16 compound treatment 9.8910601E7 2440000.0 0.21 9.7177128E7 452000.0 0.04 0.1771 0.8255 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A17 compound treatment 1.02348209E8 5880000.0 0.51 1.01194141E8 4470000.0 0.39 0.6356 0.9917 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A18 compound treatment 9.0631883E7 -5840000.0 -0.5 9.2862839E7 -3860000.0 -0.34 -0.5955 -0.9811 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A19 compound treatment 8.3525189E7 -1.29E7 -1.12 8.0672324E7 -1.61E7 -1.4 -1.784 -0.9936 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A20 compound treatment 9.8690978E7 2220000.0 0.19 9.9009843E7 2290000.0 0.2 0.2771 0.9998 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A21 compound treatment 6.5182582E7 -3.13E7 -2.7 6.5401669E7 -3.13E7 -2.74 -3.8492 -1.0 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A22 compound treatment 9.9407253E7 2940000.0 0.25 1.01523188E8 4800000.0 0.42 0.4764 0.9709 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A23 compound treatment 9.2353306E7 -4120000.0 -0.36 9.1457543E7 -5270000.0 -0.46 -0.5774 -0.9918 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 A24 compound treatment 9.8878291E7 2410000.0 0.21 1.00642114E8 3920000.0 0.34 0.3895 0.9713 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B01 compound treatment 7.7793716E7 -1.87E7 -1.61 7.0274602E7 -2.65E7 -2.31 -2.7775 -0.9844 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B02 compound treatment 9.3007129E7 -3460000.0 -0.3 9.0172051E7 -6550000.0 -0.57 -0.617 -0.9539 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B03 compound treatment 9.9505433E7 3040000.0 0.26 1.02272694E8 5550000.0 0.49 0.5287 0.9582 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B04 compound treatment 9.7937449E7 1470000.0 0.13 9.2862968E7 -3860000.0 -0.34 -0.1493 -0.4137 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B05 compound treatment 1.05280166E8 8810000.0 0.76 1.05711671E8 8990000.0 0.79 1.0943 0.9999 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B06 compound treatment 8.1847285E7 -1.46E7 -1.26 8.8377392E7 -8350000.0 -0.73 -1.4096 -0.9661 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B07 compound treatment 9.8988045E7 2520000.0 0.22 8.9912137E7 -6810000.0 -0.6 -0.2678 -0.4219 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B08 compound treatment 9.101487E7 -5450000.0 -0.47 9.2675063E7 -4050000.0 -0.35 -0.5838 -0.9902 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B09 compound treatment 9.7179228E7 710000.0 0.06 9.8943964E7 2220000.0 0.19 0.1807 0.8871 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B10 compound treatment 8.5997467E7 -1.05E7 -0.9 9.0094246E7 -6630000.0 -0.58 -1.0499 -0.977 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B11 compound treatment 9.4196283E7 -2270000.0 -0.2 9.703308E7 308000.0 0.03 -0.1198 -0.6042 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B12 compound treatment 8.723431E7 -9240000.0 -0.8 9.4238849E7 -2490000.0 -0.22 -0.7179 -0.8682 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B13 mock treatment 9.1823693E7 -4650000.0 -0.4 9.9831529E7 3110000.0 0.27 -0.0915 -0.1887 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B14 mock treatment 8.3382498E7 -1.31E7 -1.13 8.7345758E7 -9380000.0 -0.82 -1.3797 -0.9876 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B15 compound treatment 9.1137301E7 -5330000.0 -0.46 9.5229635E7 -1500000.0 -0.13 -0.4182 -0.8734 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B16 compound treatment 9.4151137E7 -2320000.0 -0.2 9.7537605E7 813000.0 0.07 -0.0913 -0.4296 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B17 compound treatment 9.1937105E7 -4530000.0 -0.39 9.6402886E7 -322000.0 -0.03 -0.2967 -0.756 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B18 compound treatment 7.9934454E7 -1.65E7 -1.43 7.9581542E7 -1.71E7 -1.5 -2.0708 -0.9997 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B19 compound treatment 8.7925737E7 -8540000.0 -0.74 9.0204969E7 -6520000.0 -0.57 -0.9253 -0.9919 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B20 compound treatment 7.4932037E7 -2.15E7 -1.86 8.0621971E7 -1.61E7 -1.41 -2.3119 -0.9906 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B21 compound treatment 9.9594696E7 3130000.0 0.27 1.0514858E8 8420000.0 0.74 0.7122 0.9071 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B22 compound treatment 9.1333038E7 -5140000.0 -0.44 9.2936214E7 -3790000.0 -0.33 -0.5482 -0.9897 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B23 compound treatment 1.08106656E8 1.16E7 1.01 1.09151259E8 1.24E7 1.09 1.4797 0.9992 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 B24 compound treatment 1.07593294E8 1.11E7 0.96 1.0926202E8 1.25E7 1.1 1.4552 0.9978 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C01 compound treatment 1.08149205E8 1.17E7 1.01 1.07143676E8 1.04E7 0.91 1.3581 0.9987 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C02 compound treatment 1.03616822E8 7150000.0 0.62 9.7636353E7 912000.0 0.08 0.4929 0.7919 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C03 compound treatment 8.9491854E7 -6980000.0 -0.6 9.2414563E7 -4310000.0 -0.38 -0.6929 -0.9745 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C04 compound treatment 7.3692771E7 -2.28E7 -1.97 7.2748935E7 -2.4E7 -2.1 -2.8748 -0.9995 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C05 compound treatment 8.828333E7 -8190000.0 -0.71 9.2120159E7 -4600000.0 -0.4 -0.7849 -0.9645 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C06 compound treatment 9.5835943E7 -634000.0 -0.05 9.6701178E7 -23500.0 0.0 -0.0402 -0.7332 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C07 compound treatment 9.1322642E7 -5150000.0 -0.44 8.9831944E7 -6890000.0 -0.6 -0.7409 -0.9887 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C08 compound treatment 9.470208E7 -1770000.0 -0.15 9.6567885E7 -157000.0 -0.01 -0.1177 -0.7676 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C09 compound treatment 5.7470172E7 -3.9E7 -3.37 6.277566E7 -3.39E7 -2.97 -4.4828 -0.998 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C10 compound treatment 6.1296107E7 -3.52E7 -3.04 6.1325257E7 -3.54E7 -3.1 -4.3389 -1.0 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C11 mock treatment 9.025557E7 -6210000.0 -0.54 9.0172217E7 -6550000.0 -0.57 -0.785 -0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C12 mock treatment 9.3123926E7 -3350000.0 -0.29 9.5750985E7 -974000.0 -0.09 -0.2646 -0.8782 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C13 compound treatment 6.902707E7 -2.74E7 -2.37 6.9704945E7 -2.7E7 -2.36 -3.3481 -1.0 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C14 compound treatment 9.0905486E7 -5560000.0 -0.48 9.3844449E7 -2880000.0 -0.25 -0.5181 -0.9546 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C15 mock treatment 8.9249575E7 -7220000.0 -0.62 9.0418334E7 -6310000.0 -0.55 -0.8312 -0.9981 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C16 mock treatment 9.7872189E7 1400000.0 0.12 9.9003617E7 2280000.0 0.2 0.2267 0.9714 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C17 compound treatment 9.0610495E7 -5860000.0 -0.51 9.5746671E7 -978000.0 -0.09 -0.4184 -0.8151 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C18 compound treatment 9.107285E7 -5400000.0 -0.47 9.220191E7 -4520000.0 -0.4 -0.6095 -0.9967 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C19 compound treatment 6.3475899E7 -3.3E7 -2.85 6.2460429E7 -3.43E7 -3.0 -4.1355 -0.9997 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C20 compound treatment 9.8435811E7 1970000.0 0.17 1.0187693E8 5150000.0 0.45 0.4389 0.911 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C21 compound treatment 4.0505132E7 -5.6E7 -4.83 4.6117373E7 -5.06E7 -4.43 -6.5498 -0.999 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C22 compound treatment 9.0912236E7 -5560000.0 -0.48 9.6642141E7 -82500.0 -0.01 -0.3445 -0.7177 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C23 compound treatment 1.07203523E8 1.07E7 0.93 9.3819869E7 -2900000.0 -0.25 0.4758 0.4949 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 C24 compound treatment 1.11658726E8 1.52E7 1.31 1.07102812E8 1.04E7 0.91 1.5699 0.9839 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D01 compound treatment 1.04170269E8 7700000.0 0.67 1.02980365E8 6260000.0 0.55 0.8574 0.9953 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D02 compound treatment 9.5489362E7 -980000.0 -0.08 8.0862516E7 -1.59E7 -1.39 -1.0415 -0.7488 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D03 compound treatment 9.2536796E7 -3930000.0 -0.34 9.9123412E7 2400000.0 0.21 -0.0918 -0.2298 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D04 compound treatment 9.6568256E7 98600.0 0.01 9.7584585E7 860000.0 0.08 0.0592 0.7821 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D05 compound treatment 9.5191977E7 -1280000.0 -0.11 9.5032709E7 -1690000.0 -0.15 -0.1827 -0.9895 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D06 compound treatment 8.1237274E7 -1.52E7 -1.32 7.0250062E7 -2.65E7 -2.32 -2.5687 -0.964 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D07 compound treatment 8.8244253E7 -8230000.0 -0.71 9.7129066E7 404000.0 0.04 -0.4773 -0.6711 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D08 compound treatment 8.6096881E7 -1.04E7 -0.9 8.9414936E7 -7310000.0 -0.64 -1.0859 -0.9864 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D09 compound treatment 9.5515608E7 -954000.0 -0.08 9.7770903E7 1050000.0 0.09 0.0065 0.0526 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D10 compound treatment 7.0511431E7 -2.6E7 -2.24 6.986025E7 -2.69E7 -2.35 -3.2479 -0.9997 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D11 mock treatment 9.0642458E7 -5830000.0 -0.5 1.00789422E8 4060000.0 0.36 -0.1043 -0.1693 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D12 mock treatment 9.434837E7 -2120000.0 -0.18 9.6201192E7 -523000.0 -0.05 -0.162 -0.8575 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D13 compound treatment 9.7872793E7 1400000.0 0.12 9.9852158E7 3130000.0 0.27 0.2792 0.9328 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D14 compound treatment 9.3015136E7 -3450000.0 -0.3 8.4464512E7 -1.23E7 -1.07 -0.9697 -0.8707 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D15 mock treatment 8.7624811E7 -8840000.0 -0.76 9.8196777E7 1470000.0 0.13 -0.4491 -0.5797 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D16 mock treatment 9.3280687E7 -3190000.0 -0.28 9.868438E7 1960000.0 0.17 -0.0735 -0.2265 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D17 compound treatment 9.5510234E7 -959000.0 -0.08 9.7110523E7 386000.0 0.03 -0.0347 -0.388 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D18 compound treatment 1.00650818E8 4180000.0 0.36 9.174441E7 -4980000.0 -0.44 -0.0528 -0.0933 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D19 compound treatment 9.1921497E7 -4550000.0 -0.39 1.02488975E8 5760000.0 0.5 0.0789 0.1235 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D20 compound treatment 9.2615883E7 -3850000.0 -0.33 1.0180349E8 5080000.0 0.44 0.0789 0.1421 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D21 compound treatment 1.03024588E8 6550000.0 0.57 1.01079352E8 4350000.0 0.38 0.6698 0.9814 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D22 compound treatment 1.07891818E8 1.14E7 0.99 9.6536808E7 -188000.0 -0.02 0.686 0.6952 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D23 compound treatment 9.9322353E7 2850000.0 0.25 1.0520906E8 8480000.0 0.74 0.6993 0.8938 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 D24 compound treatment 1.0307558E8 6610000.0 0.57 1.02905274E8 6180000.0 0.54 0.7859 0.9996 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E01 mock treatment 1.07257947E8 1.08E7 0.93 8.8078933E7 -8650000.0 -0.76 0.1239 0.1032 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E02 mock treatment 1.01454066E8 4980000.0 0.43 9.0013501E7 -6710000.0 -0.59 -0.1109 -0.1523 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E03 compound treatment 9.9753E7 3280000.0 0.28 9.8846062E7 2120000.0 0.19 0.3318 0.9789 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E04 compound treatment 1.01614741E8 5150000.0 0.44 9.7053615E7 329000.0 0.03 0.3346 0.7513 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E05 compound treatment 9.701724E7 548000.0 0.05 9.8006622E7 1280000.0 0.11 0.1128 0.9263 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E06 compound treatment 9.1258111E7 -5210000.0 -0.45 8.7324462E7 -9400000.0 -0.82 -0.9 -0.9597 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E07 compound treatment 9.8111033E7 1640000.0 0.14 9.8112106E7 1390000.0 0.12 0.1861 0.997 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E08 compound treatment 9.2082621E7 -4390000.0 -0.38 9.3941751E7 -2780000.0 -0.24 -0.4402 -0.9772 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E09 mock treatment 9.5255597E7 -1210000.0 -0.1 9.5891722E7 -833000.0 -0.07 -0.1257 -0.9842 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E10 mock treatment 9.0356745E7 -6110000.0 -0.53 9.290278E7 -3820000.0 -0.33 -0.6099 -0.9757 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E11 compound treatment 9.7206807E7 737000.0 0.06 9.7911921E7 1190000.0 0.1 0.1185 0.9724 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E12 compound treatment 5.9817837E7 -3.67E7 -3.17 5.4884065E7 -4.18E7 -3.66 -4.8278 -0.9974 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E13 compound treatment 8.7916818E7 -8550000.0 -0.74 9.0428672E7 -6300000.0 -0.55 -0.912 -0.9896 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E14 compound treatment 9.1337394E7 -5130000.0 -0.44 9.2910909E7 -3810000.0 -0.33 -0.5495 -0.9902 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E15 compound treatment 3.5326798E7 -6.11E7 -5.28 3.650972E7 -6.02E7 -5.27 -7.4606 -1.0 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E16 compound treatment 8.9568409E7 -6900000.0 -0.6 9.3322114E7 -3400000.0 -0.3 -0.6321 -0.9486 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E17 mock treatment 1.02820216E8 6350000.0 0.55 1.0583161E8 9110000.0 0.8 0.9514 0.9834 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E18 mock treatment 1.04465361E8 8000000.0 0.69 1.05165235E8 8440000.0 0.74 1.0107 0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E19 compound treatment 2.369951E7 -7.28E7 -6.29 2.5166099E7 -7.16E7 -6.26 -8.8727 -1.0 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E20 compound treatment 9.3699692E7 -2770000.0 -0.24 9.8306483E7 1580000.0 0.14 -0.0713 -0.2579 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E21 compound treatment 1.01804129E8 5330000.0 0.46 1.06283811E8 9560000.0 0.84 0.9174 0.9605 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E22 compound treatment 9.9399104E7 2930000.0 0.25 9.5941458E7 -783000.0 -0.07 0.1304 0.4976 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E23 compound treatment 9.8099231E7 1630000.0 0.14 9.9231901E7 2510000.0 0.22 0.2547 0.977 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 E24 compound treatment 1.06980601E8 1.05E7 0.91 1.05785735E8 9060000.0 0.79 1.2027 0.9977 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F01 mock treatment 1.06427356E8 9960000.0 0.86 1.06096971E8 9370000.0 0.82 1.1882 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F02 mock treatment 1.02391776E8 5920000.0 0.51 9.3154313E7 -3570000.0 -0.31 0.1407 0.2348 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F03 compound treatment 9.1700984E7 -4770000.0 -0.41 9.3357299E7 -3370000.0 -0.29 -0.4996 -0.9865 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F04 compound treatment 9.6956608E7 487000.0 0.04 9.3469075E7 -3260000.0 -0.28 -0.1717 -0.5963 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F05 compound treatment 9.5245019E7 -1220000.0 -0.11 9.3015516E7 -3710000.0 -0.32 -0.3043 -0.8914 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F06 compound treatment 9.5389354E7 -1080000.0 -0.09 9.6845762E7 121000.0 0.01 -0.0585 -0.6228 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F07 compound treatment 9.6527265E7 57600.0 0.0 9.5100268E7 -1620000.0 -0.14 -0.097 -0.6819 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F08 compound treatment 9.2288025E7 -4180000.0 -0.36 9.3436128E7 -3290000.0 -0.29 -0.4589 -0.9937 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F09 mock treatment 9.586236E7 -607000.0 -0.05 9.6830329E7 106000.0 0.01 -0.0306 -0.5736 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F10 mock treatment 9.2588421E7 -3880000.0 -0.34 9.3300726E7 -3420000.0 -0.3 -0.4489 -0.9984 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F11 compound treatment 9.8151804E7 1680000.0 0.15 9.8324516E7 1600000.0 0.14 0.2017 0.9998 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F12 compound treatment 9.1707997E7 -4760000.0 -0.41 9.5608994E7 -1120000.0 -0.1 -0.3599 -0.8513 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F13 compound treatment 9.4840253E7 -1630000.0 -0.14 9.5201657E7 -1520000.0 -0.13 -0.1938 -0.9996 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F14 compound treatment 8.9432643E7 -7040000.0 -0.61 9.3480963E7 -3240000.0 -0.28 -0.6305 -0.9399 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F15 compound treatment 8.7804513E7 -8670000.0 -0.75 8.7174776E7 -9550000.0 -0.84 -1.1202 -0.9985 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F16 compound treatment 8.0964191E7 -1.55E7 -1.34 7.5431104E7 -2.13E7 -1.86 -2.2647 -0.9869 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F17 mock treatment 1.04802779E8 8330000.0 0.72 1.05909535E8 9180000.0 0.8 1.0773 0.9985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F18 mock treatment 1.00161609E8 3690000.0 0.32 1.03808943E8 7080000.0 0.62 0.6639 0.9522 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F19 compound treatment 5.2978191E7 -4.35E7 -3.76 4.8784772E7 -4.79E7 -4.2 -5.6229 -0.9985 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F20 compound treatment 9.4226995E7 -2240000.0 -0.19 9.7190938E7 466000.0 0.04 -0.1081 -0.5462 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F21 compound treatment 9.5997157E7 -472000.0 -0.04 9.980236E7 3080000.0 0.27 0.1616 0.5932 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F22 compound treatment 9.6202527E7 -267000.0 -0.02 1.00615815E8 3890000.0 0.34 0.2245 0.6577 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F23 compound treatment 8.7517279E7 -8950000.0 -0.77 8.3754729E7 -1.3E7 -1.14 -1.3494 -0.9825 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 F24 compound treatment 1.07667244E8 1.12E7 0.97 1.04871882E8 8150000.0 0.71 1.1881 0.9888 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G01 compound treatment 3.4499187E7 -6.2E7 -5.35 3.7662987E7 -5.91E7 -5.17 -7.4398 -0.9998 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G02 compound treatment 9.7665969E7 1200000.0 0.1 9.8914749E7 2190000.0 0.19 0.2086 0.958 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G03 mock treatment 9.7062112E7 592000.0 0.05 1.00578223E8 3850000.0 0.34 0.2747 0.8052 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G04 mock treatment 9.053121E7 -5940000.0 -0.51 9.9305952E7 2580000.0 0.23 -0.2029 -0.3621 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G05 compound treatment 8.439605E7 -1.21E7 -1.04 9.4081721E7 -2640000.0 -0.23 -0.9009 -0.8434 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G06 compound treatment 6.8394856E7 -2.81E7 -2.42 9.7180722E7 456000.0 0.04 -1.6864 -0.6954 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G07 compound treatment 1.04405402E8 7940000.0 0.69 9.7507392E7 783000.0 0.07 0.5331 0.7739 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G08 compound treatment 9.2359895E7 -4110000.0 -0.35 8.3950273E7 -1.28E7 -1.12 -1.0415 -0.8879 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G09 compound treatment 1.07542335E8 1.11E7 0.96 9.6756962E7 32300.0 0.0 0.6783 0.7092 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G10 compound treatment 1.06752228E8 1.03E7 0.89 9.8256292E7 1530000.0 0.13 0.7228 0.8047 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G11 compound treatment 2.3706635E7 -7.28E7 -6.28 2.3209739E7 -7.35E7 -6.43 -8.9934 -0.9999 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G12 compound treatment 9.7697888E7 1230000.0 0.11 9.3497535E7 -3230000.0 -0.28 -0.1247 -0.4133 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G13 compound treatment 1.02664569E8 6190000.0 0.54 9.8928099E7 2200000.0 0.19 0.5147 0.905 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G14 compound treatment 9.3131665E7 -3340000.0 -0.29 9.2494538E7 -4230000.0 -0.37 -0.4656 -0.9924 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G15 compound treatment 1.00394783E8 3930000.0 0.34 9.5506017E7 -1220000.0 -0.11 0.1643 0.4623 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G16 compound treatment 9.1702842E7 -4770000.0 -0.41 8.8937734E7 -7790000.0 -0.68 -0.773 -0.9709 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G17 compound treatment 7.013419E7 -2.63E7 -2.27 6.7750748E7 -2.9E7 -2.54 -3.4015 -0.9985 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G18 compound treatment 1.01984816E8 5520000.0 0.48 9.840193E7 1680000.0 0.15 0.4406 0.884 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G19 mock treatment 1.03110524E8 6640000.0 0.57 9.5614525E7 -1110000.0 -0.1 0.3369 0.5791 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G20 mock treatment 1.00583575E8 4110000.0 0.36 1.02102107E8 5380000.0 0.47 0.584 0.9904 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G21 compound treatment 1.01815124E8 5350000.0 0.46 9.9352296E7 2630000.0 0.23 0.4891 0.9482 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G22 compound treatment 1.00292057E8 3820000.0 0.33 1.00753957E8 4030000.0 0.35 0.4828 0.9995 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G23 compound treatment 1.13491893E8 1.7E7 1.47 9.922045E7 2500000.0 0.22 1.1941 0.8033 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 G24 compound treatment 1.1337303E8 1.69E7 1.46 1.07735563E8 1.1E7 0.96 1.7138 0.9797 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H01 compound treatment 1.11027709E8 1.46E7 1.26 1.07910581E8 1.12E7 0.98 1.5814 0.9923 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H02 compound treatment 1.01443087E8 4970000.0 0.43 9.7123087E7 398000.0 0.03 0.3284 0.762 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H03 mock treatment 1.04533327E8 8060000.0 0.7 1.01778523E8 5050000.0 0.44 0.8052 0.976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H04 mock treatment 9.4917027E7 -1550000.0 -0.13 9.2899147E7 -3830000.0 -0.33 -0.3316 -0.9193 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H05 compound treatment 9.5571969E7 -898000.0 -0.08 1.00225982E8 3500000.0 0.31 0.1619 0.5121 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H06 compound treatment 1.0132395E8 4850000.0 0.42 9.5989176E7 -736000.0 -0.06 0.251 0.5916 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H07 compound treatment 1.02752788E8 6280000.0 0.54 9.8864247E7 2140000.0 0.19 0.5161 0.8991 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H08 compound treatment 9.6805239E7 336000.0 0.03 8.9177386E7 -7550000.0 -0.66 -0.4466 -0.6754 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H09 compound treatment 9.7249134E7 780000.0 0.07 9.7802599E7 1080000.0 0.09 0.1143 0.9863 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H10 compound treatment 9.5866855E7 -603000.0 -0.05 9.2593807E7 -4130000.0 -0.36 -0.2925 -0.8007 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H11 compound treatment 9.8581969E7 2110000.0 0.18 1.00320712E8 3600000.0 0.31 0.3515 0.9664 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H12 compound treatment 8.2363079E7 -1.41E7 -1.22 8.0695942E7 -1.6E7 -1.4 -1.8535 -0.9975 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H13 compound treatment 9.9400194E7 2930000.0 0.25 9.9111717E7 2390000.0 0.21 0.3267 0.9955 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H14 compound treatment 9.4294723E7 -2170000.0 -0.19 9.066888E7 -6060000.0 -0.53 -0.5076 -0.9027 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H15 compound treatment 1.02399026E8 5930000.0 0.51 9.7548982E7 824000.0 0.07 0.4131 0.7988 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H16 compound treatment 8.865363E7 -7820000.0 -0.68 9.1922489E7 -4800000.0 -0.42 -0.7745 -0.974 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H17 compound treatment 9.5075989E7 -1390000.0 -0.12 9.2225776E7 -4500000.0 -0.39 -0.3635 -0.8829 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H18 compound treatment 8.2352504E7 -1.41E7 -1.22 8.2890967E7 -1.38E7 -1.21 -1.7183 -1.0 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H19 mock treatment 1.04306731E8 7840000.0 0.68 1.00778808E8 4050000.0 0.35 0.7295 0.9546 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H20 mock treatment 9.997618E7 3510000.0 0.3 9.9409648E7 2680000.0 0.23 0.3803 0.9921 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H21 compound treatment 1.08774952E8 1.23E7 1.06 1.06406275E8 9680000.0 0.85 1.3507 0.9937 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H22 compound treatment 8.9889129E7 -6580000.0 -0.57 8.9925362E7 -6800000.0 -0.6 -0.8227 -0.9997 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H23 compound treatment 9.4414375E7 -2060000.0 -0.18 1.03398172E8 6670000.0 0.58 0.2875 0.4709 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 H24 compound treatment 1.05634218E8 9160000.0 0.79 9.6683983E7 -40700.0 0.0 0.5572 0.7039 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I01 compound treatment 3.6652377E7 -5.98E7 -5.17 4.1564869E7 -5.52E7 -4.83 -7.0668 -0.9994 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I02 compound treatment 1.05818321E8 9350000.0 0.81 9.8347407E7 1620000.0 0.14 0.6714 0.8189 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I03 compound treatment 7.0811007E7 -2.57E7 -2.22 7.2822268E7 -2.39E7 -2.09 -3.0463 -0.9996 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I04 compound treatment 9.3552925E7 -2920000.0 -0.25 9.2429719E7 -4290000.0 -0.38 -0.4439 -0.9811 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I05 mock treatment 1.00248241E8 3780000.0 0.33 9.8124179E7 1400000.0 0.12 0.3174 0.9105 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I06 mock treatment 9.871131E7 2240000.0 0.19 9.6172827E7 -552000.0 -0.05 0.1028 0.5149 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I07 compound treatment 1.00711176E8 4240000.0 0.37 9.8920977E7 2200000.0 0.19 0.395 0.9547 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I08 compound treatment 9.5575415E7 -894000.0 -0.08 9.2995204E7 -3730000.0 -0.33 -0.2854 -0.8509 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I09 compound treatment 9.2588536E7 -3880000.0 -0.34 9.3678278E7 -3050000.0 -0.27 -0.4256 -0.9936 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I10 compound treatment 9.1351247E7 -5120000.0 -0.44 9.3924481E7 -2800000.0 -0.25 -0.4859 -0.9613 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I11 compound treatment 4.2733883E7 -5.37E7 -4.64 4.7865273E7 -4.89E7 -4.28 -6.3055 -0.9992 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I12 compound treatment 9.3326255E7 -3140000.0 -0.27 9.4266606E7 -2460000.0 -0.22 -0.3441 -0.9934 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I13 compound treatment 9.9624648E7 3160000.0 0.27 9.2562124E7 -4160000.0 -0.36 -0.0649 -0.1427 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I14 compound treatment 7.9764069E7 -1.67E7 -1.44 8.6088128E7 -1.06E7 -0.93 -1.6785 -0.9775 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I15 compound treatment 3.7914321E7 -5.86E7 -5.06 3.5193621E7 -6.15E7 -5.39 -7.384 -0.9995 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I16 compound treatment 9.3927279E7 -2540000.0 -0.22 9.5022073E7 -1700000.0 -0.15 -0.2606 -0.9822 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I17 compound treatment 9.9046124E7 2580000.0 0.22 9.8661714E7 1940000.0 0.17 0.2772 0.991 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I18 compound treatment 9.706832E7 599000.0 0.05 1.00328559E8 3600000.0 0.32 0.2596 0.8122 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I19 compound treatment 9.9523351E7 3050000.0 0.26 9.86705E7 1950000.0 0.17 0.3069 0.9776 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I20 compound treatment 1.01224706E8 4760000.0 0.41 9.883601E7 2110000.0 0.18 0.4211 0.935 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I21 mock treatment 9.9797712E7 3330000.0 0.29 1.02040173E8 5320000.0 0.47 0.5322 0.9732 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I22 mock treatment 1.00511412E8 4040000.0 0.35 1.00602269E8 3880000.0 0.34 0.4868 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I23 compound treatment 8.2749497E7 -1.37E7 -1.19 9.9760689E7 3040000.0 0.27 -0.6501 -0.5353 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 I24 compound treatment 8.2428226E7 -1.4E7 -1.21 1.02227085E8 5500000.0 0.48 -0.5171 -0.3962 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J01 compound treatment 1.00385096E8 3920000.0 0.34 9.9497034E7 2770000.0 0.24 0.4107 0.9867 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J02 compound treatment 1.0033624E8 3870000.0 0.33 9.593343E7 -791000.0 -0.07 0.1872 0.5488 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J03 compound treatment 8.8781937E7 -7690000.0 -0.66 8.7751394E7 -8970000.0 -0.79 -1.0248 -0.9965 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J04 compound treatment 9.4996834E7 -1470000.0 -0.13 9.4869035E7 -1860000.0 -0.16 -0.2048 -0.9927 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J05 mock treatment 1.01210154E8 4740000.0 0.41 9.9617041E7 2890000.0 0.25 0.4685 0.9733 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J06 mock treatment 9.250679E7 -3960000.0 -0.34 9.2192269E7 -4530000.0 -0.4 -0.5225 -0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J07 compound treatment 1.02199153E8 5730000.0 0.49 9.8635697E7 1910000.0 0.17 0.4682 0.8963 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J08 compound treatment 8.1299951E7 -1.52E7 -1.31 8.0393737E7 -1.63E7 -1.43 -1.9371 -0.9991 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J09 compound treatment 9.8477553E7 2010000.0 0.17 9.8692177E7 1970000.0 0.17 0.2444 1.0 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J10 compound treatment 9.4968023E7 -1500000.0 -0.13 9.3771057E7 -2950000.0 -0.26 -0.2745 -0.9491 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J11 compound treatment 9.6686024E7 216000.0 0.02 9.7760273E7 1040000.0 0.09 0.0773 0.8353 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J12 compound treatment 5.2974704E7 -4.35E7 -3.76 5.6895875E7 -3.98E7 -3.49 -5.1212 -0.9993 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J13 compound treatment 9.6142499E7 -327000.0 -0.03 9.1541163E7 -5180000.0 -0.45 -0.3408 -0.7497 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J14 compound treatment 9.515744E7 -1310000.0 -0.11 9.7007581E7 283000.0 0.02 -0.0626 -0.5399 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J15 compound treatment 8.1351944E7 -1.51E7 -1.31 7.6277686E7 -2.04E7 -1.79 -2.1887 -0.988 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J16 compound treatment 9.3950251E7 -2520000.0 -0.22 9.5426075E7 -1300000.0 -0.11 -0.2342 -0.9541 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J17 compound treatment 9.2792698E7 -3680000.0 -0.32 9.5850375E7 -874000.0 -0.08 -0.2787 -0.8531 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J18 compound treatment 9.1526231E7 -4940000.0 -0.43 9.2793837E7 -3930000.0 -0.34 -0.5452 -0.9943 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J19 compound treatment 9.8523893E7 2050000.0 0.18 9.605012E7 -675000.0 -0.06 0.0837 0.4477 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J20 compound treatment 7.4865022E7 -2.16E7 -1.87 7.5430938E7 -2.13E7 -1.86 -2.6372 -1.0 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J21 mock treatment 9.9875E7 3410000.0 0.29 1.00740446E8 4020000.0 0.35 0.4565 0.9961 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J22 mock treatment 9.7223476E7 754000.0 0.07 9.6428922E7 -296000.0 -0.03 0.0277 0.3959 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J23 compound treatment 8.3862917E7 -1.26E7 -1.09 9.0519571E7 -6210000.0 -0.54 -1.1539 -0.9484 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 J24 compound treatment 7.800466E7 -1.85E7 -1.59 9.9691825E7 2970000.0 0.26 -0.9441 -0.5843 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K01 compound treatment 1.08669976E8 1.22E7 1.05 1.05616977E8 8890000.0 0.78 1.2954 0.9889 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K02 compound treatment 9.98609E7 3390000.0 0.29 9.8436009E7 1710000.0 0.15 0.313 0.9515 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K03 compound treatment 1.01155206E8 4690000.0 0.4 9.5565694E7 -1160000.0 -0.1 0.2144 0.514 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K04 compound treatment 9.1499275E7 -4970000.0 -0.43 8.6727999E7 -1.0E7 -0.87 -0.9222 -0.9463 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K05 compound treatment 4.2862023E7 -5.36E7 -4.63 3.3454691E7 -6.33E7 -5.54 -7.1895 -0.996 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K06 compound treatment 8.5873001E7 -1.06E7 -0.92 1.00051378E8 3330000.0 0.29 -0.4413 -0.4595 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K07 mock treatment 9.5259252E7 -1210000.0 -0.1 9.7786871E7 1060000.0 0.09 -0.0082 -0.0585 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K08 mock treatment 9.6019603E7 -450000.0 -0.04 9.464992E7 -2070000.0 -0.18 -0.1559 -0.8395 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K09 compound treatment 9.7284994E7 815000.0 0.07 9.7243482E7 519000.0 0.05 0.0819 0.9775 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K10 compound treatment 9.19865E7 -4480000.0 -0.39 9.0742754E7 -5980000.0 -0.52 -0.644 -0.989 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K11 compound treatment 6.5766732E7 -3.07E7 -2.65 3.1694069E7 -6.5E7 -5.69 -5.8995 -0.9396 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K12 compound treatment 7.9836039E7 -1.66E7 -1.44 9.069667E7 -6030000.0 -0.53 -1.3889 -0.9075 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K13 compound treatment 9.6361665E7 -108000.0 -0.01 1.0084354E8 4120000.0 0.36 0.2483 0.6886 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K14 compound treatment 8.9266453E7 -7200000.0 -0.62 8.9332413E7 -7390000.0 -0.65 -0.8974 -0.9998 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K15 mock treatment 9.7878303E7 1410000.0 0.12 7.8101168E7 -1.86E7 -1.63 -1.0665 -0.6525 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K16 mock treatment 9.3068353E7 -3400000.0 -0.29 8.0415553E7 -1.63E7 -1.43 -1.217 -0.8351 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K17 compound treatment 9.9764924E7 3300000.0 0.28 1.01988215E8 5260000.0 0.46 0.527 0.9732 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K18 compound treatment 9.8494732E7 2030000.0 0.17 9.4737851E7 -1990000.0 -0.17 7.0E-4 0.003 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K19 compound treatment 9.7396924E7 927000.0 0.08 9.0806763E7 -5920000.0 -0.52 -0.3096 -0.5907 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K20 compound treatment 9.6945789E7 476000.0 0.04 1.0176295E8 5040000.0 0.44 0.3409 0.7697 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K21 compound treatment 1.05159858E8 8690000.0 0.75 1.03551216E8 6830000.0 0.6 0.9532 0.9936 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K22 compound treatment 2.1203906E7 -7.53E7 -6.5 2.0788995E7 -7.59E7 -6.65 -9.296 -0.9999 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K23 mock treatment 1.00459047E8 3990000.0 0.34 1.04402248E8 7680000.0 0.67 0.7188 0.9519 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 K24 mock treatment 1.0466646E8 8200000.0 0.71 1.01827863E8 5100000.0 0.45 0.8164 0.9753 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L01 compound treatment 1.09977242E8 1.35E7 1.17 1.04992617E8 8270000.0 0.72 1.3366 0.9736 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L02 compound treatment 1.01275332E8 4810000.0 0.42 9.8011667E7 1290000.0 0.11 0.3731 0.8676 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L03 compound treatment 1.0387019E8 7400000.0 0.64 1.06147747E8 9420000.0 0.82 1.0351 0.9921 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L04 compound treatment 8.5834279E7 -1.06E7 -0.92 8.8487458E7 -8240000.0 -0.72 -1.1593 -0.9928 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L05 compound treatment 8.8758822E7 -7710000.0 -0.67 1.03985169E8 7260000.0 0.64 -0.0216 -0.0235 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L06 compound treatment 8.1561507E7 -1.49E7 -1.29 9.1710987E7 -5010000.0 -0.44 -1.2208 -0.8974 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L07 mock treatment 1.00609079E8 4140000.0 0.36 9.9706622E7 2980000.0 0.26 0.4373 0.988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L08 mock treatment 9.5710776E7 -759000.0 -0.07 9.5959099E7 -766000.0 -0.07 -0.0937 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L09 compound treatment 9.8254994E7 1790000.0 0.15 9.9841405E7 3120000.0 0.27 0.3019 0.9635 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L10 compound treatment 9.7923671E7 1450000.0 0.13 8.8789729E7 -7930000.0 -0.69 -0.4022 -0.57 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L11 compound treatment 6.9292195E7 -2.72E7 -2.35 8.4076454E7 -1.26E7 -1.11 -2.4426 -0.9412 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L12 compound treatment 7.7245358E7 -1.92E7 -1.66 9.775183E7 1030000.0 0.09 -1.1105 -0.6678 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L13 compound treatment 9.5824483E7 -645000.0 -0.06 9.6496326E7 -228000.0 -0.02 -0.0535 -0.9043 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L14 compound treatment 8.6044716E7 -1.04E7 -0.9 9.2319362E7 -4410000.0 -0.39 -0.9093 -0.9284 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L15 mock treatment 9.0568646E7 -5900000.0 -0.51 8.4320796E7 -1.24E7 -1.09 -1.128 -0.9406 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L16 mock treatment 8.385831E7 -1.26E7 -1.09 7.4147788E7 -2.26E7 -1.98 -2.1674 -0.9606 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L17 compound treatment 1.00318005E8 3850000.0 0.33 9.4301683E7 -2420000.0 -0.21 0.0851 0.2158 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L18 compound treatment 8.7123024E7 -9350000.0 -0.81 8.6703141E7 -1.0E7 -0.88 -1.191 -0.9991 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L19 compound treatment 9.6944065E7 474000.0 0.04 9.9868914E7 3140000.0 0.28 0.2236 0.8035 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L20 compound treatment 9.3851039E7 -2620000.0 -0.23 9.3333479E7 -3390000.0 -0.3 -0.3698 -0.991 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L21 compound treatment 9.9509601E7 3040000.0 0.26 1.0924501E8 1.25E7 1.1 0.9605 0.8524 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L22 compound treatment 8.9035427E7 -7430000.0 -0.64 8.5649933E7 -1.11E7 -0.97 -1.1394 -0.98 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L23 mock treatment 1.01530976E8 5060000.0 0.44 1.03048736E8 6320000.0 0.55 0.7005 0.9932 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 L24 mock treatment 1.02969816E8 6500000.0 0.56 1.06719969E8 1.0E7 0.87 1.0155 0.977 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M01 compound treatment 1.11064807E8 1.46E7 1.26 9.8756707E7 2030000.0 0.18 1.0171 0.7989 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M02 compound treatment 1.04371665E8 7900000.0 0.68 1.02789767E8 6070000.0 0.53 0.8579 0.9923 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M03 compound treatment 9.8425226E7 1960000.0 0.17 9.9333198E7 2610000.0 0.23 0.2809 0.989 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M04 compound treatment 9.8076578E7 1610000.0 0.14 9.0243431E7 -6480000.0 -0.57 -0.3029 -0.5188 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M05 compound treatment 1.03802205E8 7330000.0 0.63 1.03753919E8 7030000.0 0.62 0.8828 0.9999 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M06 compound treatment 9.8796257E7 2330000.0 0.2 8.872255E7 -8000000.0 -0.7 -0.3531 -0.4846 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M07 compound treatment 9.5795124E7 -675000.0 -0.06 1.00337289E8 3610000.0 0.32 0.1824 0.5673 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M08 compound treatment 1.02026441E8 5560000.0 0.48 9.4279149E7 -2450000.0 -0.21 0.188 0.3578 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M09 mock treatment 9.2210594E7 -4260000.0 -0.37 8.7326908E7 -9400000.0 -0.82 -0.8417 -0.9342 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M10 mock treatment 9.4502818E7 -1970000.0 -0.17 9.1717738E7 -5010000.0 -0.44 -0.43 -0.9149 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M11 compound treatment 7.2535691E7 -2.39E7 -2.07 7.5755489E7 -2.1E7 -1.84 -2.7594 -0.9982 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M12 compound treatment 8.2815179E7 -1.37E7 -1.18 8.097407E7 -1.58E7 -1.38 -1.8087 -0.997 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M13 mock treatment 8.8309816E7 -8160000.0 -0.7 9.7818408E7 1090000.0 0.1 -0.4307 -0.6055 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M14 mock treatment 9.6514753E7 45100.0 0.0 9.54829E7 -1240000.0 -0.11 -0.0741 -0.6813 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M15 compound treatment 9.8017787E7 1550000.0 0.13 8.9155318E7 -7570000.0 -0.66 -0.3739 -0.5532 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M16 compound treatment 9.2118266E7 -4350000.0 -0.38 8.7863859E7 -8860000.0 -0.78 -0.8141 -0.9447 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M17 compound treatment 9.2334525E7 -4140000.0 -0.36 9.5202337E7 -1520000.0 -0.13 -0.3468 -0.9097 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M18 compound treatment 9.2781711E7 -3690000.0 -0.32 9.1660773E7 -5060000.0 -0.44 -0.5386 -0.9869 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M19 compound treatment 9.7658708E7 1190000.0 0.1 9.9556848E7 2830000.0 0.25 0.2479 0.9239 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M20 compound treatment 1.02001731E8 5530000.0 0.48 9.6942453E7 218000.0 0.02 0.3513 0.7347 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M21 compound treatment 9.092075E7 -5550000.0 -0.48 8.6694712E7 -1.0E7 -0.88 -0.9596 -0.9595 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M22 compound treatment 8.7794223E7 -8680000.0 -0.75 8.7523267E7 -9200000.0 -0.81 -1.0993 -0.9994 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M23 compound treatment 1.07449195E8 1.1E7 0.95 1.10099365E8 1.34E7 1.17 1.4983 0.9945 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 M24 compound treatment 8.9441798E7 -7030000.0 -0.61 8.391023E7 -1.28E7 -1.12 -1.2222 -0.9584 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N01 compound treatment 9.5432248E7 -1040000.0 -0.09 8.6700944E7 -1.0E7 -0.88 -0.6837 -0.7753 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N02 compound treatment 8.2720212E7 -1.37E7 -1.19 8.1354439E7 -1.54E7 -1.35 -1.7909 -0.9981 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N03 compound treatment 1.03145131E8 6680000.0 0.58 1.02439719E8 5720000.0 0.5 0.7614 0.9975 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N04 compound treatment 7.3102039E7 -2.34E7 -2.02 6.8978417E7 -2.77E7 -2.43 -3.1442 -0.9958 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N05 compound treatment 1.02112722E8 5640000.0 0.49 9.5940945E7 -784000.0 -0.07 0.2961 0.6017 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N06 compound treatment 1.00669711E8 4200000.0 0.36 9.5882593E7 -842000.0 -0.07 0.2044 0.5522 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N07 compound treatment 9.809959E7 1630000.0 0.14 9.8371978E7 1650000.0 0.14 0.2015 0.9999 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N08 compound treatment 8.5536724E7 -1.09E7 -0.94 7.8971204E7 -1.78E7 -1.55 -1.7664 -0.9715 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N09 mock treatment 9.8320532E7 1850000.0 0.16 9.5389066E7 -1340000.0 -0.12 0.0304 0.1534 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N10 mock treatment 8.956392E7 -6910000.0 -0.6 9.2666498E7 -4060000.0 -0.36 -0.6729 -0.9693 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N11 compound treatment 8.7560507E7 -8910000.0 -0.77 8.7409201E7 -9320000.0 -0.82 -1.1206 -0.9996 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N12 compound treatment 6.3577091E7 -3.29E7 -2.84 6.8961486E7 -2.78E7 -2.43 -3.727 -0.997 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N13 mock treatment 9.5517139E7 -952000.0 -0.08 9.3922696E7 -2800000.0 -0.25 -0.2316 -0.8953 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N14 mock treatment 8.9198468E7 -7270000.0 -0.63 8.6508867E7 -1.02E7 -0.89 -1.0763 -0.9851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N15 compound treatment 8.0766791E7 -1.57E7 -1.36 8.2313344E7 -1.44E7 -1.26 -1.8509 -0.9993 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N16 compound treatment 7.5036644E7 -2.14E7 -1.85 8.0758316E7 -1.6E7 -1.4 -2.2971 -0.9904 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N17 compound treatment 9.3237594E7 -3230000.0 -0.28 8.5257649E7 -1.15E7 -1.0 -0.907 -0.8707 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N18 compound treatment 2.2549929E7 -7.39E7 -6.38 2.3501112E7 -7.32E7 -6.41 -9.046 -1.0 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N19 compound treatment 9.3419614E7 -3050000.0 -0.26 9.2937014E7 -3790000.0 -0.33 -0.4207 -0.9935 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N20 compound treatment 8.2023976E7 -1.44E7 -1.25 7.758578E7 -1.91E7 -1.67 -2.0667 -0.9895 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N21 compound treatment 9.6324952E7 -145000.0 -0.01 8.9164556E7 -7560000.0 -0.66 -0.4767 -0.7203 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N22 compound treatment 3.7514679E7 -5.9E7 -5.09 4.2152064E7 -5.46E7 -4.78 -6.9778 -0.9995 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N23 compound treatment 1.10644531E8 1.42E7 1.22 1.01683212E8 4960000.0 0.43 1.1726 0.9027 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 N24 compound treatment 2.1407808E7 -7.51E7 -6.48 2.1143592E7 -7.56E7 -6.61 -9.2616 -0.9999 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O01 compound treatment 1.03525141E8 7060000.0 0.61 1.01459221E8 4730000.0 0.41 0.7239 0.9823 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O02 compound treatment 9.9784734E7 3320000.0 0.29 8.7059836E7 -9660000.0 -0.85 -0.3956 -0.443 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O03 compound treatment 1.02181881E8 5710000.0 0.49 7.9951348E7 -1.68E7 -1.47 -0.6891 -0.445 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O04 compound treatment 9.3070934E7 -3400000.0 -0.29 8.9584133E7 -7140000.0 -0.62 -0.6495 -0.9407 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O05 compound treatment 9.8203528E7 1730000.0 0.15 9.8373648E7 1650000.0 0.14 0.2079 0.9998 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O06 compound treatment 1.02032097E8 5560000.0 0.48 9.5127167E7 -1600000.0 -0.14 0.2409 0.4814 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O07 compound treatment 1.0058706E8 4120000.0 0.36 9.7668434E7 944000.0 0.08 0.3099 0.8487 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O08 compound treatment 8.1755689E7 -1.47E7 -1.27 7.974691E7 -1.7E7 -1.49 -1.9493 -0.997 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O09 compound treatment 9.9060504E7 2590000.0 0.22 9.5810644E7 -914000.0 -0.08 0.1017 0.4278 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O10 compound treatment 9.6415913E7 -53700.0 0.0 9.2940887E7 -3780000.0 -0.33 -0.2374 -0.7169 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O11 mock treatment 9.2051061E7 -4420000.0 -0.38 9.4968733E7 -1760000.0 -0.15 -0.3785 -0.92 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O12 mock treatment 9.198741E7 -4480000.0 -0.39 9.2835284E7 -3890000.0 -0.34 -0.5144 -0.9979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O13 compound treatment 9.8558259E7 2090000.0 0.18 7.9864677E7 -1.69E7 -1.48 -0.9158 -0.6161 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O14 compound treatment 9.1739587E7 -4730000.0 -0.41 8.4919845E7 -1.18E7 -1.03 -1.0194 -0.9176 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O15 compound treatment 1.02316398E8 5850000.0 0.5 1.02746444E8 6020000.0 0.53 0.7297 0.9998 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O16 compound treatment 9.5277356E7 -1190000.0 -0.1 9.6743599E7 18900.0 0.0 -0.0716 -0.6956 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O17 compound treatment 1.04825675E8 8360000.0 0.72 1.01337363E8 4610000.0 0.4 0.7958 0.9623 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O18 compound treatment 9.7547076E7 1080000.0 0.09 9.5716798E7 -1010000.0 -0.09 0.0034 0.0268 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O19 compound treatment 8.6449993E7 -1.0E7 -0.87 9.0414932E7 -6310000.0 -0.55 -1.0024 -0.9765 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O20 compound treatment 1.00644849E8 4180000.0 0.36 9.8413594E7 1690000.0 0.15 0.3595 0.9225 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O21 compound treatment 1.02614524E8 6140000.0 0.53 1.02994504E8 6270000.0 0.55 0.7633 0.9999 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O22 compound treatment 9.2517038E7 -3950000.0 -0.34 9.3480659E7 -3240000.0 -0.28 -0.4422 -0.9958 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O23 compound treatment 9.7628438E7 1160000.0 0.1 1.02939414E8 6210000.0 0.54 0.4554 0.8234 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 O24 compound treatment 1.05678063E8 9210000.0 0.8 9.9203536E7 2480000.0 0.22 0.7158 0.8683 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P01 compound treatment 7.985741E7 -1.66E7 -1.43 8.0988618E7 -1.57E7 -1.38 -1.9884 -0.9998 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P02 compound treatment 2.1998381E7 -7.45E7 -6.43 2.6853869E7 -6.99E7 -6.11 -8.8722 -0.9997 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P03 compound treatment 1.05313229E8 8840000.0 0.76 8.8366965E7 -8360000.0 -0.73 0.0229 0.0217 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P04 compound treatment 8.3496175E7 -1.3E7 -1.12 7.5739508E7 -2.1E7 -1.84 -2.091 -0.9719 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P05 compound treatment 8.7134774E7 -9330000.0 -0.81 8.159259E7 -1.51E7 -1.32 -1.5066 -0.9717 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P06 compound treatment 2.885529E7 -6.76E7 -5.84 3.3986998E7 -6.27E7 -5.49 -8.012 -0.9995 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P07 compound treatment 1.00970742E8 4500000.0 0.39 9.6419333E7 -305000.0 -0.03 0.256 0.657 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P08 compound treatment 7.2232894E7 -2.42E7 -2.09 6.7055842E7 -2.97E7 -2.6 -3.3163 -0.9943 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P09 compound treatment 1.0416852E8 7700000.0 0.66 9.9007765E7 2280000.0 0.2 0.6115 0.8807 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P10 compound treatment 8.4902595E7 -1.16E7 -1.0 8.2404117E7 -1.43E7 -1.25 -1.5927 -0.9937 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P11 mock treatment 9.8128084E7 1660000.0 0.14 9.687599E7 151000.0 0.01 0.1107 0.7692 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P12 mock treatment 9.3125501E7 -3340000.0 -0.29 9.1929926E7 -4790000.0 -0.42 -0.501 -0.9834 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P13 compound treatment 9.969799E7 3230000.0 0.28 6.6429968E7 -3.03E7 -2.65 -1.6776 -0.6293 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P14 compound treatment 7.9867744E7 -1.66E7 -1.43 7.0649904E7 -2.61E7 -2.28 -2.6276 -0.9749 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P15 compound treatment 9.5347755E7 -1120000.0 -0.1 9.7392639E7 668000.0 0.06 -0.0272 -0.2402 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P16 compound treatment 8.4835132E7 -1.16E7 -1.0 8.103646E7 -1.57E7 -1.37 -1.6814 -0.9882 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P17 compound treatment 1.04406233E8 7940000.0 0.69 1.00186717E8 3460000.0 0.3 0.699 0.9326 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P18 compound treatment 6.7096292E7 -2.94E7 -2.54 6.9417822E7 -2.73E7 -2.39 -3.4838 -0.9996 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P19 compound treatment 1.01999338E8 5530000.0 0.48 1.02015694E8 5290000.0 0.46 0.6652 0.9999 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P20 compound treatment 7.5386254E7 -2.11E7 -1.82 8.0031312E7 -1.67E7 -1.46 -2.3207 -0.994 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P21 compound treatment 1.06466919E8 1.0E7 0.86 1.05487008E8 8760000.0 0.77 1.1528 0.9982 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P22 compound treatment 8.2985436E7 -1.35E7 -1.16 8.1517186E7 -1.52E7 -1.33 -1.7646 -0.9978 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P23 compound treatment 1.0767232E8 1.12E7 0.97 1.07894601E8 1.12E7 0.98 1.3754 1.0 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2098 P24 compound treatment 1.02680922E8 6210000.0 0.54 1.02968087E8 6240000.0 0.55 0.7657 1.0 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A01 compound treatment 1.02098289E8 7270000.0 0.63 9.9688736E7 8570000.0 0.75 0.9744 0.9961 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A02 compound treatment 1.05684979E8 1.09E7 0.94 1.00801976E8 9680000.0 0.85 1.2624 0.9987 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A03 compound treatment 1.01998977E8 7170000.0 0.62 9.9381249E7 8260000.0 0.72 0.9493 0.997 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A04 compound treatment 9.9235906E7 4410000.0 0.38 9.5813818E7 4690000.0 0.41 0.5598 0.9993 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A05 compound treatment 9.4039728E7 -786000.0 -0.07 9.0496653E7 -623000.0 -0.05 -0.0866 -0.9941 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A06 compound treatment 9.7850373E7 3020000.0 0.26 9.6027883E7 4910000.0 0.43 0.4884 0.9716 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A07 compound treatment 1.00742254E8 5920000.0 0.51 9.6283127E7 5160000.0 0.45 0.6809 0.9981 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A08 compound treatment 9.3212864E7 -1610000.0 -0.14 9.110743E7 -12600.0 0.0 -0.0993 -0.7127 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A09 compound treatment 8.9379749E7 -5450000.0 -0.47 8.4043712E7 -7080000.0 -0.62 -0.7705 -0.9908 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A10 compound treatment 9.2212462E7 -2610000.0 -0.23 8.6974704E7 -4150000.0 -0.36 -0.4161 -0.9739 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A11 compound treatment 9.5513128E7 687000.0 0.06 9.2357927E7 1240000.0 0.11 0.1186 0.9599 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A12 compound treatment 8.7558701E7 -7270000.0 -0.63 7.8345097E7 -1.28E7 -1.12 -1.2344 -0.9627 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A13 mock treatment 8.4578599E7 -1.02E7 -0.89 7.7006614E7 -1.41E7 -1.24 -1.4992 -0.9866 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A14 mock treatment 9.4920901E7 95200.0 0.01 7.9510407E7 -1.16E7 -1.02 -0.7126 -0.7014 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A15 compound treatment 9.2296488E7 -2530000.0 -0.22 8.2587779E7 -8530000.0 -0.75 -0.6825 -0.8772 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A16 compound treatment 9.1942657E7 -2880000.0 -0.25 8.6360807E7 -4760000.0 -0.42 -0.4706 -0.9698 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A17 compound treatment 8.8607622E7 -6220000.0 -0.54 8.2050193E7 -9070000.0 -0.79 -0.941 -0.9819 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A18 compound treatment 9.4040229E7 -785000.0 -0.07 9.0805783E7 -314000.0 -0.03 -0.0674 -0.921 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A19 compound treatment 9.8468821E7 3640000.0 0.31 9.4153144E7 3030000.0 0.27 0.4102 0.9964 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A20 compound treatment 9.4597311E7 -228000.0 -0.02 9.0594323E7 -526000.0 -0.05 -0.0465 -0.9285 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A21 compound treatment 9.0402622E7 -4420000.0 -0.38 8.4259855E7 -6860000.0 -0.6 -0.6947 -0.9762 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A22 compound treatment 9.8199435E7 3370000.0 0.29 9.907234E7 7950000.0 0.7 0.6982 0.9253 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A23 compound treatment 1.05626816E8 1.08E7 0.93 9.9878575E7 8760000.0 0.77 1.2017 0.9952 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 A24 compound treatment 1.00110385E8 5280000.0 0.46 9.8509628E7 7390000.0 0.65 0.7801 0.9855 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B01 compound treatment 1.09875652E8 1.5E7 1.3 1.05127834E8 1.4E7 1.23 1.786 0.9996 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B02 compound treatment 1.03865019E8 9040000.0 0.78 8.8212013E7 -2910000.0 -0.25 0.3721 0.4531 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B03 compound treatment 1.04188861E8 9360000.0 0.81 9.8362529E7 7240000.0 0.63 1.02 0.9927 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B04 compound treatment 8.4518245E7 -1.03E7 -0.89 9.1666012E7 546000.0 0.05 -0.5957 -0.6682 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B05 compound treatment 9.9358153E7 4530000.0 0.39 9.5398333E7 4280000.0 0.37 0.5416 0.9998 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B06 compound treatment 9.9190959E7 4370000.0 0.38 8.764408E7 -3480000.0 -0.3 0.0515 0.1063 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B07 compound treatment 9.8230002E7 3400000.0 0.29 9.5038851E7 3920000.0 0.34 0.4504 0.9971 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B08 compound treatment 8.466957E7 -1.02E7 -0.88 9.2685661E7 1570000.0 0.14 -0.5234 -0.5895 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B09 compound treatment 9.1587312E7 -3240000.0 -0.28 9.4474301E7 3350000.0 0.29 0.0098 0.0242 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B10 compound treatment 8.8649444E7 -6180000.0 -0.53 7.9529273E7 -1.16E7 -1.01 -1.0945 -0.955 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B11 compound treatment 9.4860275E7 34600.0 0.0 9.0238752E7 -881000.0 -0.08 -0.0524 -0.6792 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B12 compound treatment 7.899159E7 -1.58E7 -1.37 8.1613339E7 -9510000.0 -0.83 -1.5554 -0.9716 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B13 mock treatment 8.5501015E7 -9320000.0 -0.81 8.1357511E7 -9760000.0 -0.85 -1.1736 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B14 mock treatment 8.8092509E7 -6730000.0 -0.58 8.0507125E7 -1.06E7 -0.93 -1.068 -0.9746 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B15 compound treatment 9.2899238E7 -1930000.0 -0.17 8.3720938E7 -7400000.0 -0.65 -0.5755 -0.8608 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B16 compound treatment 8.1721173E7 -1.31E7 -1.13 7.5477143E7 -1.56E7 -1.37 -1.7684 -0.9955 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B17 compound treatment 9.4908475E7 82800.0 0.01 9.0715319E7 -405000.0 -0.04 -0.02 -0.5532 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B18 compound treatment 9.0394922E7 -4430000.0 -0.38 9.0696071E7 -424000.0 -0.04 -0.2968 -0.772 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B19 compound treatment 1.0150035E8 6670000.0 0.58 9.5960327E7 4840000.0 0.42 0.7072 0.9885 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B20 compound treatment 8.5360241E7 -9470000.0 -0.82 8.3288208E7 -7830000.0 -0.69 -1.0628 -0.9962 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B21 compound treatment 9.9123609E7 4300000.0 0.37 9.6314807E7 5190000.0 0.45 0.584 0.9949 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B22 compound treatment 9.6438435E7 1610000.0 0.14 9.7158197E7 6040000.0 0.53 0.4722 0.864 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B23 compound treatment 1.05150443E8 1.03E7 0.89 1.0564527E8 1.45E7 1.27 1.5295 0.985 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 B24 compound treatment 9.502058E7 195000.0 0.02 9.4180509E7 3060000.0 0.27 0.2013 0.7501 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C01 compound treatment 1.06860706E8 1.2E7 1.04 1.01358927E8 1.02E7 0.9 1.3687 0.9973 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C02 compound treatment 1.02418647E8 7590000.0 0.66 9.9525277E7 8410000.0 0.74 0.9839 0.9984 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C03 compound treatment 1.0018446E8 5360000.0 0.46 9.0734561E7 -385000.0 -0.03 0.3034 0.6538 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C04 compound treatment 9.3970255E7 -855000.0 -0.07 9.7113125E7 5990000.0 0.52 0.3186 0.6016 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C05 compound treatment 9.8079256E7 3250000.0 0.28 9.6066626E7 4950000.0 0.43 0.5048 0.9781 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C06 compound treatment 8.5844016E7 -8980000.0 -0.78 9.5123152E7 4000000.0 0.35 -0.3008 -0.3534 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C07 compound treatment 9.5291741E7 466000.0 0.04 8.5293672E7 -5830000.0 -0.51 -0.3321 -0.6493 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C08 compound treatment 9.0594906E7 -4230000.0 -0.37 8.908861E7 -2030000.0 -0.18 -0.3841 -0.9452 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C09 compound treatment 8.7282801E7 -7540000.0 -0.65 8.7163591E7 -3960000.0 -0.35 -0.7055 -0.9563 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C10 compound treatment 8.3317298E7 -1.15E7 -0.99 8.3333916E7 -7790000.0 -0.68 -1.1847 -0.983 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C11 mock treatment 9.0592959E7 -4230000.0 -0.37 8.1174426E7 -9950000.0 -0.87 -0.874 -0.9258 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C12 mock treatment 8.476969E7 -1.01E7 -0.87 8.0001917E7 -1.11E7 -0.97 -1.3022 -0.9984 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C13 compound treatment 8.4311045E7 -1.05E7 -0.91 8.4491259E7 -6630000.0 -0.58 -1.0524 -0.9766 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C14 compound treatment 7.8245326E7 -1.66E7 -1.43 7.913453E7 -1.2E7 -1.05 -1.7544 -0.9883 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C15 mock treatment 8.8557187E7 -6270000.0 -0.54 7.7767489E7 -1.34E7 -1.17 -1.2092 -0.9388 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C16 mock treatment 9.0405113E7 -4420000.0 -0.38 8.3871323E7 -7250000.0 -0.63 -0.7186 -0.9705 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C17 compound treatment 8.8320072E7 -6510000.0 -0.56 8.2443999E7 -8680000.0 -0.76 -0.9342 -0.989 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C18 compound treatment 8.3676016E7 -1.11E7 -0.96 9.2114692E7 995000.0 0.09 -0.6194 -0.6406 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C19 compound treatment 9.5367143E7 541000.0 0.05 8.3362263E7 -7760000.0 -0.68 -0.447 -0.6568 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C20 compound treatment 9.5738201E7 913000.0 0.08 9.715502E7 6030000.0 0.53 0.4292 0.8037 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C21 compound treatment 1.01252383E8 6430000.0 0.56 9.6834764E7 5710000.0 0.5 0.7462 0.9986 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C22 compound treatment 9.0754311E7 -4070000.0 -0.35 9.0673203E7 -447000.0 -0.04 -0.2763 -0.7809 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C23 compound treatment 1.04656577E8 9830000.0 0.85 1.0096605E8 9850000.0 0.86 1.2097 1.0 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 C24 compound treatment 1.0922065E8 1.44E7 1.24 1.00690639E8 9570000.0 0.84 1.4714 0.9815 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D01 compound treatment 9.6570605E7 1740000.0 0.15 1.03042602E8 1.19E7 1.04 0.8444 0.8009 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D02 compound treatment 1.03116248E8 8290000.0 0.72 8.8684273E7 -2440000.0 -0.21 0.3556 0.476 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D03 compound treatment 1.04050643E8 9220000.0 0.8 9.7361445E7 6240000.0 0.55 0.9497 0.983 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D04 compound treatment 9.1024286E7 -3800000.0 -0.33 8.405479E7 -7070000.0 -0.62 -0.6694 -0.9561 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D05 compound treatment 8.6196325E7 -8630000.0 -0.75 9.4032997E7 2910000.0 0.25 -0.3468 -0.4402 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D06 compound treatment 9.2782217E7 -2040000.0 -0.18 8.3223751E7 -7900000.0 -0.69 -0.6135 -0.8601 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D07 compound treatment 9.9436184E7 4610000.0 0.4 9.6561177E7 5440000.0 0.48 0.6183 0.996 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D08 compound treatment 8.9158134E7 -5670000.0 -0.49 8.9016814E7 -2100000.0 -0.18 -0.4763 -0.9107 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D09 compound treatment 9.5672023E7 846000.0 0.07 9.2291225E7 1170000.0 0.1 0.1242 0.9863 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D10 compound treatment 8.6841892E7 -7980000.0 -0.69 7.8612881E7 -1.25E7 -1.09 -1.2616 -0.9752 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D11 mock treatment 8.4366331E7 -1.05E7 -0.9 9.0920183E7 -200000.0 -0.02 -0.6512 -0.7207 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D12 mock treatment 8.5494435E7 -9330000.0 -0.81 8.2625846E7 -8490000.0 -0.74 -1.0956 -0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D13 compound treatment 8.9231949E7 -5590000.0 -0.48 8.9680913E7 -1440000.0 -0.13 -0.4307 -0.8626 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D14 compound treatment 7.2860166E7 -2.2E7 -1.9 6.7483E7 -2.36E7 -2.07 -2.8043 -0.9991 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D15 mock treatment 8.5594207E7 -9230000.0 -0.8 8.8942812E7 -2180000.0 -0.19 -0.6985 -0.8521 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D16 mock treatment 9.3596973E7 -1230000.0 -0.11 8.7293755E7 -3830000.0 -0.33 -0.3118 -0.8877 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D17 compound treatment 9.3308522E7 -1520000.0 -0.13 8.6110282E7 -5010000.0 -0.44 -0.4027 -0.88 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D18 compound treatment 9.8037173E7 3210000.0 0.28 8.4257371E7 -6860000.0 -0.6 -0.2286 -0.3455 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D19 compound treatment 9.4066608E7 -759000.0 -0.07 9.597057E7 4850000.0 0.42 0.2538 0.5909 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D20 compound treatment 1.01475451E8 6650000.0 0.57 9.5919144E7 4800000.0 0.42 0.7031 0.9882 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D21 compound treatment 1.06275947E8 1.15E7 0.99 8.9613036E7 -1510000.0 -0.13 0.6061 0.6074 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D22 compound treatment 1.01360126E8 6530000.0 0.56 9.7358289E7 6240000.0 0.55 0.7851 0.9999 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D23 compound treatment 1.00120994E8 5300000.0 0.46 1.06228095E8 1.51E7 1.32 1.2584 0.8994 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 D24 compound treatment 1.02508602E8 7680000.0 0.66 9.9399912E7 8280000.0 0.72 0.9816 0.999 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E01 mock treatment 1.05320961E8 1.05E7 0.91 8.8449564E7 -2670000.0 -0.23 0.4757 0.5082 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E02 mock treatment 9.8192616E7 3370000.0 0.29 9.7810622E7 6690000.0 0.59 0.6197 0.9478 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E03 compound treatment 1.02404877E8 7580000.0 0.65 9.8458517E7 7340000.0 0.64 0.917 1.0 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E04 compound treatment 1.00342923E8 5520000.0 0.48 9.2498642E7 1380000.0 0.12 0.4223 0.859 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E05 compound treatment 9.7730982E7 2910000.0 0.25 9.3092287E7 1970000.0 0.17 0.2995 0.9833 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E06 compound treatment 9.1031485E7 -3790000.0 -0.33 9.2481764E7 1360000.0 0.12 -0.1475 -0.4229 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E07 compound treatment 9.7217791E7 2390000.0 0.21 9.2751727E7 1630000.0 0.14 0.2471 0.9837 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E08 compound treatment 9.078011E7 -4050000.0 -0.35 8.6363418E7 -4760000.0 -0.42 -0.5414 -0.9962 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E09 mock treatment 9.1610754E7 -3210000.0 -0.28 8.8739688E7 -2380000.0 -0.21 -0.3437 -0.99 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E10 mock treatment 8.5929646E7 -8900000.0 -0.77 8.2439738E7 -8680000.0 -0.76 -1.0805 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E11 compound treatment 7.349468E7 -2.13E7 -1.84 8.0110668E7 -1.1E7 -0.96 -1.9841 -0.9543 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E12 compound treatment 8.7812811E7 -7010000.0 -0.61 8.2103021E7 -9020000.0 -0.79 -0.9863 -0.9915 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E13 compound treatment 8.6101656E7 -8720000.0 -0.75 8.4110491E7 -7010000.0 -0.61 -0.9666 -0.9948 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E14 compound treatment 8.2948585E7 -1.19E7 -1.03 7.7655565E7 -1.35E7 -1.18 -1.5586 -0.9976 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E15 compound treatment 8.7200853E7 -7620000.0 -0.66 8.4675663E7 -6440000.0 -0.56 -0.8645 -0.997 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E16 compound treatment 8.9615291E7 -5210000.0 -0.45 7.8443916E7 -1.27E7 -1.11 -1.1027 -0.9211 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E17 mock treatment 9.6796725E7 1970000.0 0.17 9.3160722E7 2040000.0 0.18 0.2467 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E18 mock treatment 9.6806836E7 1980000.0 0.17 9.6013728E7 4890000.0 0.43 0.4238 0.919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E19 compound treatment 9.0358761E7 -4470000.0 -0.39 8.775364E7 -3370000.0 -0.29 -0.4811 -0.9911 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E20 compound treatment 9.1117454E7 -3710000.0 -0.32 9.6235023E7 5110000.0 0.45 0.0901 0.1636 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E21 compound treatment 1.00710225E8 5880000.0 0.51 9.8495593E7 7380000.0 0.65 0.8158 0.993 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E22 compound treatment 9.535771E7 532000.0 0.05 9.6989033E7 5870000.0 0.51 0.3957 0.7673 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E23 compound treatment 1.00456475E8 5630000.0 0.49 9.5848361E7 4730000.0 0.41 0.6365 0.9968 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 E24 compound treatment 1.03362836E8 8540000.0 0.74 1.01889194E8 1.08E7 0.94 1.1878 0.9926 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F01 mock treatment 1.0303407E8 8210000.0 0.71 1.0269913E8 1.16E7 1.01 1.2179 0.9847 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F02 mock treatment 9.7934175E7 3110000.0 0.27 9.8787165E7 7670000.0 0.67 0.6643 0.9192 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F03 compound treatment 1.01544708E8 6720000.0 0.58 1.00907253E8 9790000.0 0.86 1.016 0.982 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F04 compound treatment 9.7578784E7 2750000.0 0.24 9.4466347E7 3350000.0 0.29 0.3752 0.9947 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F05 compound treatment 9.9147993E7 4320000.0 0.37 9.8150948E7 7030000.0 0.62 0.6991 0.9713 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F06 compound treatment 9.6821062E7 2000000.0 0.17 9.4927771E7 3810000.0 0.33 0.3575 0.9529 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F07 compound treatment 9.6685393E7 1860000.0 0.16 9.6179163E7 5060000.0 0.44 0.4267 0.9059 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F08 compound treatment 8.9313249E7 -5510000.0 -0.48 8.8973692E7 -2150000.0 -0.19 -0.4695 -0.9173 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F09 mock treatment 9.5008489E7 183000.0 0.02 9.1145674E7 25600.0 0.0 0.0128 0.7996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F10 mock treatment 8.8628635E7 -6200000.0 -0.54 8.4974573E7 -6150000.0 -0.54 -0.7588 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F11 compound treatment 9.256235E7 -2260000.0 -0.2 9.1679555E7 560000.0 0.05 -0.1036 -0.5141 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F12 compound treatment 8.912851E7 -5700000.0 -0.49 8.499311E7 -6130000.0 -0.54 -0.7271 -0.9991 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F13 compound treatment 9.302894E7 -1800000.0 -0.16 8.7460521E7 -3660000.0 -0.32 -0.3362 -0.9447 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F14 compound treatment 8.4779161E7 -1.0E7 -0.87 8.3954984E7 -7170000.0 -0.63 -1.057 -0.9873 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F15 compound treatment 9.3184016E7 -1640000.0 -0.14 8.9432724E7 -1690000.0 -0.15 -0.2047 -0.9998 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F16 compound treatment 8.587683E7 -8950000.0 -0.77 8.0977806E7 -1.01E7 -0.89 -1.1742 -0.9976 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F17 mock treatment 1.00005839E8 5180000.0 0.45 9.772453E7 6600000.0 0.58 0.7251 0.992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F18 mock treatment 9.751779E7 2690000.0 0.23 9.4181106E7 3060000.0 0.27 0.3539 0.9975 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F19 compound treatment 9.8641578E7 3820000.0 0.33 9.4176914E7 3060000.0 0.27 0.4222 0.9946 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F20 compound treatment 9.5765224E7 940000.0 0.08 9.178445E7 664000.0 0.06 0.0985 0.9866 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F21 compound treatment 1.03387852E8 8560000.0 0.74 9.8665282E7 7550000.0 0.66 0.9899 0.9984 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F22 compound treatment 9.8936429E7 4110000.0 0.36 9.3599659E7 2480000.0 0.22 0.4045 0.9721 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F23 compound treatment 1.06088054E8 1.13E7 0.97 8.5700259E7 -5420000.0 -0.47 0.3524 0.3257 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 F24 compound treatment 1.03441282E8 8620000.0 0.74 1.00746537E8 9630000.0 0.84 1.1219 0.9981 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G01 compound treatment 1.06394384E8 1.16E7 1.0 1.03946777E8 1.28E7 1.12 1.5003 0.9983 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G02 compound treatment 1.01795828E8 6970000.0 0.6 1.0071292E8 9590000.0 0.84 1.0193 0.9867 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G03 mock treatment 1.0274047E8 7910000.0 0.68 1.00393596E8 9270000.0 0.81 1.0573 0.9964 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G04 mock treatment 9.2427237E7 -2400000.0 -0.21 9.4253288E7 3130000.0 0.27 0.0474 0.138 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G05 compound treatment 9.6015752E7 1190000.0 0.1 9.6351811E7 5230000.0 0.46 0.3964 0.8448 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G06 compound treatment 9.4774976E7 -50700.0 0.0 9.0617727E7 -502000.0 -0.04 -0.0342 -0.7737 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G07 compound treatment 9.6575938E7 1750000.0 0.15 9.185739E7 737000.0 0.06 0.1525 0.9279 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G08 compound treatment 9.1674705E7 -3150000.0 -0.27 8.7605898E7 -3510000.0 -0.31 -0.4099 -0.9981 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G09 compound treatment 9.3853263E7 -972000.0 -0.08 8.7674394E7 -3450000.0 -0.3 -0.2726 -0.8709 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G10 compound treatment 8.6081806E7 -8740000.0 -0.76 8.4633009E7 -6490000.0 -0.57 -0.9355 -0.9901 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G11 compound treatment 9.2240424E7 -2590000.0 -0.22 8.8030708E7 -3090000.0 -0.27 -0.3491 -0.9955 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G12 compound treatment 8.8014446E7 -6810000.0 -0.59 7.9621344E7 -1.15E7 -1.01 -1.1276 -0.9673 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G13 compound treatment 9.1217544E7 -3610000.0 -0.31 8.7989461E7 -3130000.0 -0.27 -0.4141 -0.9979 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G14 compound treatment 8.6930236E7 -7900000.0 -0.68 8.5390916E7 -5730000.0 -0.5 -0.8368 -0.9886 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G15 compound treatment 8.8617173E7 -6210000.0 -0.54 7.8209925E7 -1.29E7 -1.13 -1.1781 -0.942 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G16 compound treatment 9.0036474E7 -4790000.0 -0.41 8.1827603E7 -9290000.0 -0.81 -0.8676 -0.9508 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G17 compound treatment 9.2425342E7 -2400000.0 -0.21 8.7420963E7 -3700000.0 -0.32 -0.3755 -0.9768 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G18 compound treatment 9.3418965E7 -1410000.0 -0.12 8.6807867E7 -4310000.0 -0.38 -0.3528 -0.8898 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G19 mock treatment 9.7697706E7 2870000.0 0.25 9.3905811E7 2790000.0 0.24 0.3478 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G20 mock treatment 9.0950379E7 -3880000.0 -0.33 9.4109649E7 2990000.0 0.26 -0.0517 -0.1216 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G21 compound treatment 1.01660525E8 6830000.0 0.59 9.244561E7 1330000.0 0.12 0.4995 0.8302 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G22 compound treatment 9.9902625E7 5080000.0 0.44 9.8933575E7 7810000.0 0.68 0.7936 0.9769 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G23 compound treatment 1.02571428E8 7750000.0 0.67 9.3733245E7 2610000.0 0.23 0.6348 0.8978 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 G24 compound treatment 1.04960289E8 1.01E7 0.88 9.6323066E7 5200000.0 0.46 0.941 0.9536 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H01 compound treatment 1.07829677E8 1.3E7 1.12 1.03749798E8 1.26E7 1.11 1.5758 1.0 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H02 compound treatment 1.00837133E8 6010000.0 0.52 1.0319787E8 1.21E7 1.06 1.1146 0.9464 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H03 mock treatment 1.05502022E8 1.07E7 0.92 1.05717486E8 1.46E7 1.28 1.5554 0.9872 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H04 mock treatment 9.3317289E7 -1510000.0 -0.13 8.9650834E7 -1470000.0 -0.13 -0.183 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H05 compound treatment 9.8580646E7 3750000.0 0.32 9.8006682E7 6890000.0 0.6 0.6555 0.9577 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H06 compound treatment 9.5210439E7 385000.0 0.03 9.2057421E7 937000.0 0.08 0.0815 0.9209 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H07 compound treatment 9.4672054E7 -154000.0 -0.01 9.3872797E7 2750000.0 0.24 0.161 0.6671 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H08 compound treatment 8.5946868E7 -8880000.0 -0.77 8.4436928E7 -6680000.0 -0.58 -0.9558 -0.9911 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H09 compound treatment 9.6356453E7 1530000.0 0.13 9.1002112E7 -118000.0 -0.01 0.0862 0.6499 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H10 compound treatment 8.9094124E7 -5730000.0 -0.5 8.2384896E7 -8740000.0 -0.76 -0.8906 -0.9779 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H11 compound treatment 9.7241429E7 2420000.0 0.21 9.1954507E7 834000.0 0.07 0.1992 0.901 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H12 compound treatment 8.7900167E7 -6930000.0 -0.6 8.4608316E7 -6510000.0 -0.57 -0.8259 -0.9997 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H13 compound treatment 9.4221995E7 -604000.0 -0.05 8.6994543E7 -4130000.0 -0.36 -0.2922 -0.8009 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H14 compound treatment 8.9727133E7 -5100000.0 -0.44 8.165786E7 -9460000.0 -0.83 -0.897 -0.9563 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H15 compound treatment 9.4757861E7 -67800.0 -0.01 8.7548874E7 -3570000.0 -0.31 -0.2251 -0.7202 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H16 compound treatment 8.849447E7 -6330000.0 -0.55 8.2468543E7 -8650000.0 -0.76 -0.9221 -0.9872 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H17 compound treatment 8.9715395E7 -5110000.0 -0.44 8.7089502E7 -4030000.0 -0.35 -0.5615 -0.9938 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H18 compound treatment 9.4354848E7 -471000.0 -0.04 8.816189E7 -2960000.0 -0.26 -0.2118 -0.8083 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H19 mock treatment 1.01329441E8 6500000.0 0.56 9.5812046E7 4690000.0 0.41 0.6876 0.9881 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H20 mock treatment 9.8488288E7 3660000.0 0.32 8.9772467E7 -1350000.0 -0.12 0.1403 0.4156 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H21 compound treatment 1.06078334E8 1.13E7 0.97 9.8846154E7 7730000.0 0.68 1.1654 0.9843 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H22 compound treatment 1.00794489E8 5970000.0 0.52 9.7606661E7 6490000.0 0.57 0.766 0.9988 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H23 compound treatment 1.03816412E8 8990000.0 0.78 1.04528152E8 1.34E7 1.17 1.3789 0.9799 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 H24 compound treatment 1.04265099E8 9440000.0 0.82 1.03368476E8 1.22E7 1.07 1.3345 0.9909 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I01 compound treatment 1.05883995E8 1.11E7 0.96 1.04253895E8 1.31E7 1.15 1.4882 0.9958 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I02 compound treatment 9.9311049E7 4490000.0 0.39 9.9154647E7 8030000.0 0.7 0.7712 0.9605 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I03 compound treatment 1.0117456E8 6350000.0 0.55 9.932434E7 8200000.0 0.72 0.8955 0.9911 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I04 compound treatment 9.8075974E7 3250000.0 0.28 9.6992441E7 5870000.0 0.51 0.5619 0.9595 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I05 mock treatment 9.6633373E7 1810000.0 0.16 9.6117455E7 5000000.0 0.44 0.4197 0.9037 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I06 mock treatment 9.1886929E7 -2940000.0 -0.25 9.1353104E7 233000.0 0.02 -0.1651 -0.6482 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I07 compound treatment 9.4952178E7 126000.0 0.01 9.2865777E7 1750000.0 0.15 0.1158 0.7557 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I08 compound treatment 9.0613884E7 -4210000.0 -0.36 8.7665812E7 -3450000.0 -0.3 -0.471 -0.9958 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I09 compound treatment 9.2345125E7 -2480000.0 -0.21 8.8693529E7 -2430000.0 -0.21 -0.3017 -1.0 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I10 compound treatment 9.1110091E7 -3720000.0 -0.32 8.6201257E7 -4920000.0 -0.43 -0.5313 -0.9895 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I11 compound treatment 9.1160858E7 -3660000.0 -0.32 8.5610026E7 -5510000.0 -0.48 -0.5648 -0.9792 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I12 compound treatment 8.6102117E7 -8720000.0 -0.75 8.155319E7 -9570000.0 -0.84 -1.1248 -0.9986 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I13 compound treatment 9.077416E7 -4050000.0 -0.35 8.7916034E7 -3200000.0 -0.28 -0.4457 -0.994 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I14 compound treatment 9.0350553E7 -4480000.0 -0.39 8.6365809E7 -4750000.0 -0.42 -0.5675 -0.9993 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I15 compound treatment 9.3385515E7 -1440000.0 -0.12 8.5806808E7 -5310000.0 -0.47 -0.4168 -0.8658 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I16 compound treatment 9.2436701E7 -2390000.0 -0.21 8.1807686E7 -9310000.0 -0.81 -0.7222 -0.859 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I17 compound treatment 9.3940175E7 -886000.0 -0.08 8.9894111E7 -1230000.0 -0.11 -0.1299 -0.9862 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I18 compound treatment 9.197249E7 -2850000.0 -0.25 8.7684325E7 -3440000.0 -0.3 -0.3869 -0.9951 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I19 compound treatment 9.8823327E7 4000000.0 0.35 9.3520155E7 2400000.0 0.21 0.3927 0.9716 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I20 compound treatment 9.4580966E7 -245000.0 -0.02 9.1952678E7 833000.0 0.07 0.0366 0.4821 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I21 mock treatment 9.91202E7 4290000.0 0.37 9.5356542E7 4240000.0 0.37 0.5245 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I22 mock treatment 9.5994479E7 1170000.0 0.1 9.4189022E7 3070000.0 0.27 0.2613 0.9107 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I23 compound treatment 1.03074869E8 8250000.0 0.71 1.00773251E8 9650000.0 0.84 1.1012 0.9964 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 I24 compound treatment 1.03062491E8 8240000.0 0.71 9.929588E7 8180000.0 0.72 1.009 1.0 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J01 compound treatment 1.03030511E8 8200000.0 0.71 1.04216459E8 1.31E7 1.15 1.3116 0.9733 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J02 compound treatment 1.01360147E8 6530000.0 0.56 9.5472042E7 4350000.0 0.38 0.6684 0.9817 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J03 compound treatment 1.03172394E8 8350000.0 0.72 9.8669967E7 7550000.0 0.66 0.977 0.9991 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J04 compound treatment 9.5781708E7 956000.0 0.08 9.2315331E7 1200000.0 0.1 0.1324 0.9931 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J05 mock treatment 1.01375607E8 6550000.0 0.57 9.7422321E7 6300000.0 0.55 0.79 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J06 mock treatment 8.9154136E7 -5670000.0 -0.49 8.8846626E7 -2270000.0 -0.2 -0.4871 -0.9212 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J07 compound treatment 1.00399062E8 5570000.0 0.48 9.7640563E7 6520000.0 0.57 0.7439 0.9964 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J08 compound treatment 9.4480044E7 -346000.0 -0.03 8.9246337E7 -1870000.0 -0.16 -0.1371 -0.8223 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J09 compound treatment 9.7496993E7 2670000.0 0.23 9.2070551E7 951000.0 0.08 0.222 0.905 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J10 compound treatment 9.0019268E7 -4810000.0 -0.42 8.5023909E7 -6100000.0 -0.53 -0.6708 -0.9923 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J11 compound treatment 9.4587056E7 -239000.0 -0.02 8.8894559E7 -2230000.0 -0.19 -0.1523 -0.7776 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J12 compound treatment 8.8390468E7 -6440000.0 -0.56 8.0133371E7 -1.1E7 -0.96 -1.0729 -0.9661 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J13 compound treatment 9.6785495E7 1960000.0 0.17 8.7748583E7 -3370000.0 -0.3 -0.0889 -0.2615 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J14 compound treatment 9.369975E7 -1130000.0 -0.1 8.538168E7 -5740000.0 -0.5 -0.4239 -0.8286 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J15 compound treatment 9.2913408E7 -1910000.0 -0.17 8.9236602E7 -1880000.0 -0.16 -0.2333 -1.0 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J16 compound treatment 8.5923912E7 -8900000.0 -0.77 8.3817307E7 -7300000.0 -0.64 -0.9956 -0.9958 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J17 compound treatment 9.5951318E7 1130000.0 0.1 8.905361E7 -2070000.0 -0.18 -0.0591 -0.288 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J18 compound treatment 9.3040287E7 -1790000.0 -0.15 8.6831535E7 -4290000.0 -0.38 -0.3744 -0.9228 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J19 compound treatment 1.00956747E8 6130000.0 0.53 9.2487126E7 1370000.0 0.12 0.4591 0.8456 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J20 compound treatment 9.5933697E7 1110000.0 0.1 8.8811165E7 -2310000.0 -0.2 -0.0752 -0.3364 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J21 mock treatment 1.01749011E8 6920000.0 0.6 9.7013738E7 5890000.0 0.52 0.7876 0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J22 mock treatment 9.8816836E7 3990000.0 0.34 9.2743985E7 1620000.0 0.14 0.3443 0.9232 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J23 compound treatment 9.6184948E7 1360000.0 0.12 1.01325223E8 1.02E7 0.89 0.7146 0.7932 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 J24 compound treatment 1.02966373E8 8140000.0 0.7 9.8144617E7 7020000.0 0.61 0.9319 0.9978 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K01 compound treatment 1.07531337E8 1.27E7 1.1 1.01210514E8 1.01E7 0.88 1.4004 0.9942 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K02 compound treatment 9.5993864E7 1170000.0 0.1 9.4622202E7 3500000.0 0.31 0.2881 0.8928 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K03 compound treatment 9.3290566E7 -1540000.0 -0.13 8.0981787E7 -1.01E7 -0.89 -0.7212 -0.8038 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K04 compound treatment 9.5517167E7 691000.0 0.06 9.4060804E7 2940000.0 0.26 0.2242 0.8486 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K05 compound treatment 9.9136035E7 4310000.0 0.37 9.8980901E7 7860000.0 0.69 0.7497 0.9584 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K06 compound treatment 9.6283921E7 1460000.0 0.13 9.4732008E7 3610000.0 0.32 0.3126 0.9186 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K07 mock treatment 9.5789334E7 964000.0 0.08 9.3654138E7 2530000.0 0.22 0.2157 0.9105 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K08 mock treatment 9.1803198E7 -3020000.0 -0.26 9.3185216E7 2070000.0 0.18 -0.0568 -0.1789 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K09 compound treatment 9.0529457E7 -4300000.0 -0.37 8.7818905E7 -3300000.0 -0.29 -0.4667 -0.9923 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K10 compound treatment 9.2209183E7 -2620000.0 -0.23 8.6005266E7 -5110000.0 -0.45 -0.4763 -0.9499 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K11 compound treatment 9.3481034E7 -1340000.0 -0.12 9.1347033E7 227000.0 0.02 -0.0681 -0.5778 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K12 compound treatment 9.1690693E7 -3130000.0 -0.27 8.5749559E7 -5370000.0 -0.47 -0.5238 -0.9657 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K13 compound treatment 9.4048057E7 -778000.0 -0.07 9.1653369E7 533000.0 0.05 -0.0145 -0.1771 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K14 compound treatment 9.1938061E7 -2890000.0 -0.25 8.6711884E7 -4410000.0 -0.39 -0.4492 -0.9777 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K15 mock treatment 9.6818664E7 1990000.0 0.17 8.0029861E7 -1.11E7 -0.97 -0.5646 -0.5728 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K16 mock treatment 8.8465195E7 -6360000.0 -0.55 7.4704065E7 -1.64E7 -1.44 -1.4044 -0.913 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K17 compound treatment 9.9009396E7 4180000.0 0.36 9.4116132E7 3000000.0 0.26 0.4409 0.9876 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K18 compound treatment 9.2391196E7 -2430000.0 -0.21 9.194596E7 826000.0 0.07 -0.0976 -0.4388 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K19 compound treatment 8.5553254E7 -9270000.0 -0.8 8.9985536E7 -1130000.0 -0.1 -0.6365 -0.7887 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K20 compound treatment 9.7945936E7 3120000.0 0.27 9.8036119E7 6920000.0 0.61 0.6186 0.9336 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K21 compound treatment 1.03727792E8 8900000.0 0.77 9.7077453E7 5960000.0 0.52 0.9124 0.9821 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K22 compound treatment 1.02169423E8 7340000.0 0.63 9.7613168E7 6490000.0 0.57 0.8503 0.9985 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K23 mock treatment 1.03133392E8 8310000.0 0.72 9.4410663E7 3290000.0 0.29 0.711 0.9196 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 K24 mock treatment 1.04596025E8 9770000.0 0.84 9.9298519E7 8180000.0 0.72 1.1028 0.9966 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L01 compound treatment 1.02336625E8 7510000.0 0.65 9.5197337E7 4080000.0 0.36 0.711 0.9604 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L02 compound treatment 9.6846384E7 2020000.0 0.17 9.6983682E7 5860000.0 0.51 0.4863 0.8971 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L03 compound treatment 1.05622461E8 1.08E7 0.93 1.0493206E8 1.38E7 1.21 1.5142 0.9918 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L04 compound treatment 9.6261227E7 1440000.0 0.12 8.8442421E7 -2680000.0 -0.23 -0.078 -0.2943 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L05 compound treatment 1.00997102E8 6170000.0 0.53 9.6276464E7 5160000.0 0.45 0.696 0.9966 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L06 compound treatment 9.5636392E7 811000.0 0.07 8.9514233E7 -1610000.0 -0.14 -0.0499 -0.3176 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L07 mock treatment 9.7213443E7 2390000.0 0.21 9.9086516E7 7970000.0 0.7 0.6388 0.8786 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L08 mock treatment 9.5062724E7 237000.0 0.02 8.9291038E7 -1830000.0 -0.16 -0.0987 -0.6117 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L09 compound treatment 9.4917531E7 91800.0 0.01 8.9179368E7 -1940000.0 -0.17 -0.1145 -0.6733 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L10 compound treatment 9.243514E7 -2390000.0 -0.21 9.1165522E7 45500.0 0.0 -0.1432 -0.6933 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L11 compound treatment 9.675541E7 1930000.0 0.17 8.8923584E7 -2200000.0 -0.19 -0.0181 -0.071 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L12 compound treatment 8.6079878E7 -8750000.0 -0.76 8.3169602E7 -7950000.0 -0.7 -1.0262 -0.9992 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L13 compound treatment 9.7122987E7 2300000.0 0.2 9.1767674E7 648000.0 0.06 0.1804 0.8741 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L14 compound treatment 8.8444513E7 -6380000.0 -0.55 8.5736494E7 -5380000.0 -0.47 -0.7229 -0.997 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L15 mock treatment 9.2697148E7 -2130000.0 -0.18 8.3022244E7 -8100000.0 -0.71 -0.6311 -0.862 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L16 mock treatment 9.168709E7 -3140000.0 -0.27 6.9043717E7 -2.21E7 -1.93 -1.5579 -0.7985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L17 compound treatment 9.4356463E7 -469000.0 -0.04 8.7559098E7 -3560000.0 -0.31 -0.249 -0.7924 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L18 compound treatment 9.5143567E7 318000.0 0.03 9.0202751E7 -917000.0 -0.08 -0.0374 -0.4402 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L19 compound treatment 9.7335312E7 2510000.0 0.22 9.6264376E7 5140000.0 0.45 0.4716 0.9439 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L20 compound treatment 9.8555163E7 3730000.0 0.32 9.5815863E7 4700000.0 0.41 0.5184 0.9927 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L21 compound treatment 1.02969162E8 8140000.0 0.7 9.983351E7 8710000.0 0.76 1.0366 0.9992 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L22 compound treatment 1.0107969E8 6250000.0 0.54 9.0594341E7 -526000.0 -0.05 0.3494 0.6445 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L23 mock treatment 9.999879E7 5170000.0 0.45 1.05281946E8 1.42E7 1.24 1.1923 0.905 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 L24 mock treatment 1.06501326E8 1.17E7 1.01 1.02503592E8 1.14E7 1.0 1.4175 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M01 compound treatment 1.05154851E8 1.03E7 0.89 1.03156395E8 1.2E7 1.05 1.3757 0.9966 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M02 compound treatment 9.7588893E7 2760000.0 0.24 9.4074286E7 2950000.0 0.26 0.3516 0.9992 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M03 compound treatment 1.06182887E8 1.14E7 0.98 1.0553944E8 1.44E7 1.26 1.586 0.9922 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M04 compound treatment 9.4013254E7 -812000.0 -0.07 9.8960385E7 7840000.0 0.69 0.4356 0.6315 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M05 compound treatment 9.6162178E7 1340000.0 0.12 9.2925426E7 1810000.0 0.16 0.1934 0.9881 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M06 compound treatment 9.1298168E7 -3530000.0 -0.3 9.7533898E7 6410000.0 0.56 0.1815 0.2841 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M07 compound treatment 1.0344227E8 8620000.0 0.74 9.3061776E7 1940000.0 0.17 0.6464 0.8468 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M08 compound treatment 7.9991275E7 -1.48E7 -1.28 8.1135522E7 -9980000.0 -0.87 -1.5239 -0.9826 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M09 mock treatment 9.8286848E7 3460000.0 0.3 9.3483287E7 2360000.0 0.21 0.3576 0.9838 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M10 mock treatment 9.5632226E7 807000.0 0.07 9.028486E7 -835000.0 -0.07 -0.0024 -0.024 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M11 compound treatment 7.8691166E7 -1.61E7 -1.39 7.5750656E7 -1.54E7 -1.35 -1.9365 -0.9998 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M12 compound treatment 9.0007406E7 -4820000.0 -0.42 9.5318046E7 4200000.0 0.37 -0.0345 -0.0621 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M13 mock treatment 9.4273532E7 -552000.0 -0.05 8.8655218E7 -2460000.0 -0.22 -0.1863 -0.8431 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M14 mock treatment 8.8550491E7 -6280000.0 -0.54 8.1966828E7 -9150000.0 -0.8 -0.9497 -0.9819 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M15 compound treatment 8.8018894E7 -6810000.0 -0.59 8.9908248E7 -1210000.0 -0.11 -0.4907 -0.8214 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M16 compound treatment 8.8259313E7 -6570000.0 -0.57 9.0275565E7 -844000.0 -0.07 -0.4533 -0.7925 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M17 compound treatment 9.7880772E7 3060000.0 0.26 8.5530642E7 -5590000.0 -0.49 -0.1593 -0.2866 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M18 compound treatment 9.513626E7 311000.0 0.03 9.1015385E7 -105000.0 -0.01 0.0125 0.4407 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M19 compound treatment 9.093264E7 -3890000.0 -0.34 9.4818313E7 3700000.0 0.32 -0.0089 -0.0191 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M20 compound treatment 8.8167944E7 -6660000.0 -0.58 8.4658307E7 -6460000.0 -0.57 -0.8065 -1.0 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M21 compound treatment 1.01352624E8 6530000.0 0.56 8.8063904E7 -3060000.0 -0.27 0.2095 0.3358 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M22 compound treatment 9.7081313E7 2260000.0 0.19 9.2500845E7 1380000.0 0.12 0.2232 0.9736 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M23 compound treatment 9.6139705E7 1310000.0 0.11 1.03368521E8 1.22E7 1.07 0.8382 0.7776 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 M24 compound treatment 1.04120738E8 9300000.0 0.8 9.1848898E7 729000.0 0.06 0.6128 0.7609 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N01 compound treatment 1.05701791E8 1.09E7 0.94 9.9465416E7 8350000.0 0.73 1.1807 0.9923 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N02 compound treatment 9.1395508E7 -3430000.0 -0.3 9.8483586E7 7360000.0 0.64 0.2462 0.3471 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N03 compound treatment 1.0767307E8 1.28E7 1.11 9.4565156E7 3450000.0 0.3 0.9978 0.8678 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N04 compound treatment 9.5925411E7 1100000.0 0.09 9.4226835E7 3110000.0 0.27 0.2594 0.9007 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N05 compound treatment 9.68436E7 2020000.0 0.17 1.02722997E8 1.16E7 1.02 0.8413 0.8165 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N06 compound treatment 9.6646656E7 1820000.0 0.16 8.5823099E7 -5300000.0 -0.46 -0.2166 -0.4424 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N07 compound treatment 9.9632195E7 4810000.0 0.42 9.2948552E7 1830000.0 0.16 0.4067 0.9141 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N08 compound treatment 8.6020399E7 -8810000.0 -0.76 9.0477735E7 -642000.0 -0.06 -0.5775 -0.7573 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N09 mock treatment 9.9563697E7 4740000.0 0.41 8.7786625E7 -3330000.0 -0.29 0.0831 0.1653 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N10 mock treatment 9.1105911E7 -3720000.0 -0.32 9.1463088E7 343000.0 0.03 -0.206 -0.6382 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N11 compound treatment 8.6116391E7 -8710000.0 -0.75 9.1519798E7 400000.0 0.03 -0.5072 -0.6735 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N12 compound treatment 9.501552E7 190000.0 0.02 7.3751095E7 -1.74E7 -1.52 -1.0633 -0.6994 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N13 mock treatment 1.00278416E8 5450000.0 0.47 9.1153761E7 33700.0 0.0 0.3351 0.7115 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N14 mock treatment 8.6861918E7 -7960000.0 -0.69 9.0106785E7 -1010000.0 -0.09 -0.5491 -0.7917 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N15 compound treatment 8.3551909E7 -1.13E7 -0.97 8.2415782E7 -8700000.0 -0.76 -1.2272 -0.9926 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N16 compound treatment 9.6291878E7 1470000.0 0.13 9.0198585E7 -921000.0 -0.08 0.0325 0.2166 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N17 compound treatment 9.6606064E7 1780000.0 0.15 9.3180126E7 2060000.0 0.18 0.2362 0.9969 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N18 compound treatment 9.3524359E7 -1300000.0 -0.11 8.4109197E7 -7010000.0 -0.61 -0.5133 -0.8229 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N19 compound treatment 1.01830712E8 7010000.0 0.61 9.5796704E7 4680000.0 0.41 0.7172 0.9819 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N20 compound treatment 9.4392436E7 -433000.0 -0.04 9.2767953E7 1650000.0 0.14 0.0755 0.5069 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N21 compound treatment 1.10461534E8 1.56E7 1.35 8.0579918E7 -1.05E7 -0.92 0.3027 0.1851 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N22 compound treatment 1.01445769E8 6620000.0 0.57 9.3442478E7 2320000.0 0.2 0.548 0.9031 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N23 compound treatment 9.6617504E7 1790000.0 0.15 1.01051118E8 9930000.0 0.87 0.724 0.8201 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 N24 compound treatment 1.06306972E8 1.15E7 0.99 1.02056941E8 1.09E7 0.96 1.378 0.9998 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O01 compound treatment 1.04048321E8 9220000.0 0.8 8.879423E7 -2330000.0 -0.2 0.4193 0.51 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O02 compound treatment 9.7651171E7 2830000.0 0.24 8.8249183E7 -2870000.0 -0.25 -0.0051 -0.0145 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O03 compound treatment 1.07234855E8 1.24E7 1.07 9.3813225E7 2690000.0 0.24 0.9246 0.8425 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O04 compound treatment 9.4769689E7 -56000.0 0.0 9.6477773E7 5360000.0 0.47 0.3281 0.6998 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O05 compound treatment 1.0214787E8 7320000.0 0.63 1.01880852E8 1.08E7 0.94 1.1131 0.9812 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O06 compound treatment 9.9851703E7 5030000.0 0.43 9.8062043E7 6940000.0 0.61 0.7366 0.9864 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O07 compound treatment 1.00571043E8 5750000.0 0.5 9.8886235E7 7770000.0 0.68 0.8315 0.9881 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O08 compound treatment 9.352381E7 -1300000.0 -0.11 9.4506205E7 3390000.0 0.3 0.13 0.4103 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O09 compound treatment 9.6765148E7 1940000.0 0.17 9.2747195E7 1630000.0 0.14 0.2191 0.9967 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O10 compound treatment 8.8728478E7 -6100000.0 -0.53 8.8882729E7 -2240000.0 -0.2 -0.5108 -0.9092 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O11 mock treatment 9.8718781E7 3890000.0 0.34 9.3377485E7 2260000.0 0.2 0.3775 0.9679 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O12 mock treatment 9.0504463E7 -4320000.0 -0.37 9.0117372E7 -1000000.0 -0.09 -0.326 -0.8502 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O13 compound treatment 9.9359958E7 4530000.0 0.39 9.4362045E7 3240000.0 0.28 0.4776 0.9875 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O14 compound treatment 9.4847638E7 22000.0 0.0 8.7924683E7 -3200000.0 -0.28 -0.1964 -0.7023 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O15 compound treatment 9.676061E7 1930000.0 0.17 9.349585E7 2380000.0 0.21 0.2652 0.9941 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O16 compound treatment 9.3832263E7 -993000.0 -0.09 9.1027233E7 -92800.0 -0.01 -0.0664 -0.7706 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O17 compound treatment 9.8585291E7 3760000.0 0.32 9.7814756E7 6690000.0 0.59 0.6439 0.9612 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O18 compound treatment 9.2891852E7 -1930000.0 -0.17 9.3767863E7 2650000.0 0.23 0.0458 0.1602 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O19 compound treatment 1.03998848E8 9170000.0 0.79 9.8693863E7 7570000.0 0.66 1.0289 0.9961 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O20 compound treatment 9.5682451E7 857000.0 0.07 9.4788805E7 3670000.0 0.32 0.2794 0.8478 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O21 compound treatment 1.03565599E8 8740000.0 0.75 9.6486285E7 5370000.0 0.47 0.8659 0.9739 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O22 compound treatment 1.00849523E8 6020000.0 0.52 9.7819497E7 6700000.0 0.59 0.7825 0.9982 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O23 compound treatment 1.01596769E8 6770000.0 0.58 1.03457952E8 1.23E7 1.08 1.1771 0.9585 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 O24 compound treatment 1.05591573E8 1.08E7 0.93 9.9731666E7 8610000.0 0.75 1.1904 0.9946 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P01 compound treatment 1.06185649E8 1.14E7 0.98 7.4923072E7 -1.62E7 -1.42 -0.3085 -0.179 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P02 compound treatment 9.8062671E7 3240000.0 0.28 8.072257E7 -1.04E7 -0.91 -0.4457 -0.4682 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P03 compound treatment 1.03038731E8 8210000.0 0.71 8.991859E7 -1200000.0 -0.11 0.4273 0.5958 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P04 compound treatment 9.9868648E7 5040000.0 0.44 9.9580038E7 8460000.0 0.74 0.8315 0.968 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P05 compound treatment 1.07421851E8 1.26E7 1.09 1.04617922E8 1.35E7 1.18 1.6046 0.9992 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P06 compound treatment 9.7122317E7 2300000.0 0.2 9.5737369E7 4620000.0 0.4 0.426 0.9463 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P07 compound treatment 1.04805423E8 9980000.0 0.86 1.01181467E8 1.01E7 0.88 1.2322 0.9999 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P08 compound treatment 9.7304678E7 2480000.0 0.21 9.4317614E7 3200000.0 0.28 0.3493 0.9913 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P09 compound treatment 1.00794648E8 5970000.0 0.52 8.2353086E7 -8770000.0 -0.77 -0.178 -0.1925 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P10 compound treatment 8.9839376E7 -4990000.0 -0.43 9.2236962E7 1120000.0 0.1 -0.2354 -0.5331 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P11 mock treatment 9.6906727E7 2080000.0 0.18 9.4783458E7 3660000.0 0.32 0.3538 0.9626 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P12 mock treatment 9.3954525E7 -871000.0 -0.08 9.273603E7 1620000.0 0.14 0.0468 0.2921 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P13 compound treatment 9.6764914E7 1940000.0 0.17 9.7637851E7 6520000.0 0.57 0.5218 0.8777 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P14 compound treatment 9.2810296E7 -2020000.0 -0.17 9.12398E7 120000.0 0.01 -0.1157 -0.6633 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P15 compound treatment 9.6817016E7 1990000.0 0.17 9.5038347E7 3920000.0 0.34 0.3641 0.9491 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P16 compound treatment 9.4067222E7 -758000.0 -0.07 9.0386865E7 -733000.0 -0.06 -0.0917 -0.9999 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P17 compound treatment 1.0191464E8 7090000.0 0.61 9.8386331E7 7270000.0 0.64 0.8826 0.9998 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P18 compound treatment 1.00502311E8 5680000.0 0.49 9.3099523E7 1980000.0 0.17 0.4692 0.9023 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P19 compound treatment 1.08342648E8 1.35E7 1.17 1.03063873E8 1.19E7 1.05 1.5647 0.9985 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P20 compound treatment 1.0166597E8 6840000.0 0.59 9.4844423E7 3720000.0 0.33 0.6482 0.9607 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P21 compound treatment 1.07641216E8 1.28E7 1.11 1.02573147E8 1.15E7 1.0 1.4915 0.9988 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P22 compound treatment 1.0377897E8 8950000.0 0.77 9.8064037E7 6940000.0 0.61 0.9765 0.9929 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P23 compound treatment 1.08647637E8 1.38E7 1.19 1.056362E8 1.45E7 1.27 1.7425 0.9995 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2100 P24 compound treatment 1.08648484E8 1.38E7 1.19 1.02804086E8 1.17E7 1.02 1.5673 0.997 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A01 compound treatment 1.15546216E8 1.77E7 1.53 9.5432108E7 4140000.0 0.36 1.3378 0.8512 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A02 compound treatment 1.13628907E8 1.58E7 1.36 9.7210818E7 5920000.0 0.52 1.3308 0.9122 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A03 compound treatment 1.03698248E8 5860000.0 0.51 9.8534959E7 7250000.0 0.63 0.8062 0.9937 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A04 compound treatment 9.5133649E7 -2710000.0 -0.23 9.9576176E7 8290000.0 0.73 0.3476 0.4561 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A05 compound treatment 1.02122391E8 4280000.0 0.37 8.6079445E7 -5210000.0 -0.46 -0.0608 -0.1036 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A06 compound treatment 1.0268696E8 4850000.0 0.42 9.3541416E7 2250000.0 0.2 0.4355 0.941 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A07 compound treatment 8.8857284E7 -8980000.0 -0.78 9.4997327E7 3710000.0 0.32 -0.3191 -0.3794 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A08 compound treatment 9.8896863E7 1060000.0 0.09 9.2783832E7 1500000.0 0.13 0.1571 0.9845 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A09 compound treatment 9.5151037E7 -2690000.0 -0.23 8.1213111E7 -1.01E7 -0.88 -0.7877 -0.8639 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A10 compound treatment 9.4510071E7 -3330000.0 -0.29 8.8050724E7 -3240000.0 -0.28 -0.4037 -1.0 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A11 compound treatment 8.2649875E7 -1.52E7 -1.31 8.5711447E7 -5580000.0 -0.49 -1.2728 -0.9093 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A12 compound treatment 8.8013645E7 -9830000.0 -0.85 8.2821003E7 -8470000.0 -0.74 -1.1241 -0.9977 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A13 mock treatment 8.7185403E7 -1.07E7 -0.92 7.6973969E7 -1.43E7 -1.25 -1.5365 -0.9885 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A14 mock treatment 8.7875549E7 -9960000.0 -0.86 8.4533816E7 -6750000.0 -0.59 -1.0266 -0.9832 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A15 compound treatment 7.9908204E7 -1.79E7 -1.55 8.6353086E7 -4930000.0 -0.43 -1.4006 -0.8711 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A16 compound treatment 9.4674141E7 -3170000.0 -0.27 8.5921768E7 -5370000.0 -0.47 -0.5255 -0.9669 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A17 compound treatment 9.5463603E7 -2380000.0 -0.21 8.213594E7 -9150000.0 -0.8 -0.7115 -0.8605 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A18 compound treatment 9.141946E7 -6420000.0 -0.55 9.3040322E7 1750000.0 0.15 -0.2837 -0.4931 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A19 compound treatment 8.805046E7 -9790000.0 -0.85 9.4600044E7 3310000.0 0.29 -0.3929 -0.4396 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A20 compound treatment 9.6261987E7 -1580000.0 -0.14 9.8617083E7 7330000.0 0.64 0.3572 0.5447 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A21 compound treatment 1.01277397E8 3440000.0 0.3 9.1805202E7 517000.0 0.05 0.2419 0.8056 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A22 compound treatment 9.9260032E7 1420000.0 0.12 9.973562E7 8450000.0 0.74 0.6095 0.8133 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A23 compound treatment 9.2946512E7 -4890000.0 -0.42 9.9960587E7 8670000.0 0.76 0.2378 0.2737 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 A24 compound treatment 1.0472709E8 6890000.0 0.59 9.6898692E7 5610000.0 0.49 0.7678 0.9955 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B01 compound treatment 1.06427916E8 8590000.0 0.74 1.0255674E8 1.13E7 0.99 1.2218 0.9901 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B02 compound treatment 9.2537844E7 -5300000.0 -0.46 8.6093808E7 -5190000.0 -0.45 -0.6453 -1.0 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B03 compound treatment 9.71378E7 -702000.0 -0.06 9.4539723E7 3250000.0 0.28 0.1583 0.5441 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B04 compound treatment 9.5320231E7 -2520000.0 -0.22 9.3042399E7 1750000.0 0.15 -0.0453 -0.1702 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B05 compound treatment 9.5541641E7 -2300000.0 -0.2 9.8305322E7 7020000.0 0.61 0.2939 0.4553 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B06 compound treatment 8.7513271E7 -1.03E7 -0.89 8.4848006E7 -6440000.0 -0.56 -1.0292 -0.9755 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B07 compound treatment 9.3582627E7 -4260000.0 -0.37 9.5452589E7 4160000.0 0.36 -0.0023 -0.0045 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B08 compound treatment 9.451777E7 -3320000.0 -0.29 8.9338206E7 -1950000.0 -0.17 -0.3236 -0.9692 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B09 compound treatment 8.9841326E7 -8000000.0 -0.69 9.0099674E7 -1190000.0 -0.1 -0.5621 -0.8045 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B10 compound treatment 8.0934533E7 -1.69E7 -1.46 7.7216752E7 -1.41E7 -1.23 -1.9033 -0.9964 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B11 compound treatment 8.7092495E7 -1.07E7 -0.93 8.578746E7 -5500000.0 -0.48 -0.9968 -0.9532 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B12 compound treatment 8.2778614E7 -1.51E7 -1.3 8.2298765E7 -8990000.0 -0.79 -1.4762 -0.971 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B13 mock treatment 8.2420389E7 -1.54E7 -1.33 8.7531711E7 -3760000.0 -0.33 -1.1742 -0.856 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B14 mock treatment 7.3785122E7 -2.41E7 -2.08 7.5519595E7 -1.58E7 -1.38 -2.445 -0.9802 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B15 compound treatment 8.964526E7 -8190000.0 -0.71 9.0289446E7 -999000.0 -0.09 -0.5623 -0.7884 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B16 compound treatment 8.7503121E7 -1.03E7 -0.89 8.6435137E7 -4850000.0 -0.42 -0.9316 -0.9423 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B17 compound treatment 9.4221947E7 -3620000.0 -0.31 9.4227702E7 2940000.0 0.26 -0.0391 -0.0965 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B18 compound treatment 8.242525E7 -1.54E7 -1.33 8.098459E7 -1.03E7 -0.9 -1.5791 -0.982 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B19 compound treatment 9.750821E7 -332000.0 -0.03 9.679386E7 5510000.0 0.48 0.3204 0.6639 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B20 compound treatment 8.5657532E7 -1.22E7 -1.05 9.161522E7 327000.0 0.03 -0.7238 -0.6876 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B21 compound treatment 1.01388643E8 3550000.0 0.31 1.00740704E8 9450000.0 0.83 0.8017 0.9087 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B22 compound treatment 8.676529E7 -1.11E7 -0.96 8.9270306E7 -2020000.0 -0.18 -0.8013 -0.8237 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B23 compound treatment 1.05522981E8 7680000.0 0.66 1.05078595E8 1.38E7 1.21 1.3226 0.9603 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 B24 compound treatment 1.0410772E8 6270000.0 0.54 1.02287245E8 1.1E7 0.96 1.0635 0.9629 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C01 compound treatment 1.08773645E8 1.09E7 0.94 1.01015844E8 9730000.0 0.85 1.2698 0.9987 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C02 compound treatment 1.06019053E8 8180000.0 0.71 9.6769671E7 5480000.0 0.48 0.8387 0.9822 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C03 compound treatment 9.5358925E7 -2480000.0 -0.21 8.8965E7 -2320000.0 -0.2 -0.2953 -0.9997 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C04 compound treatment 1.01828189E8 3990000.0 0.34 9.6111121E7 4820000.0 0.42 0.542 0.9949 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C05 compound treatment 9.4442113E7 -3400000.0 -0.29 9.4265849E7 2980000.0 0.26 -0.0233 -0.0592 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C06 compound treatment 1.00877588E8 3040000.0 0.26 9.3290159E7 2000000.0 0.18 0.3094 0.9807 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C07 compound treatment 8.9829677E7 -8010000.0 -0.69 8.5290176E7 -6000000.0 -0.52 -0.8604 -0.9907 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C08 compound treatment 9.226179E7 -5580000.0 -0.48 8.8523699E7 -2760000.0 -0.24 -0.5118 -0.9492 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C09 compound treatment 8.9871782E7 -7970000.0 -0.69 8.7382192E7 -3910000.0 -0.34 -0.7284 -0.9478 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C10 compound treatment 8.2352022E7 -1.55E7 -1.34 8.3207353E7 -8080000.0 -0.71 -1.446 -0.9556 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C11 mock treatment 8.9753184E7 -8090000.0 -0.7 7.9547337E7 -1.17E7 -1.03 -1.2205 -0.9823 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C12 mock treatment 8.5091357E7 -1.27E7 -1.1 8.4967911E7 -6320000.0 -0.55 -1.1697 -0.9493 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C13 compound treatment 8.3129375E7 -1.47E7 -1.27 8.7754593E7 -3530000.0 -0.31 -1.1171 -0.8543 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C14 compound treatment 8.7920499E7 -9920000.0 -0.86 8.112622E7 -1.02E7 -0.89 -1.2347 -0.9998 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C15 mock treatment 9.0609041E7 -7230000.0 -0.62 7.7131691E7 -1.42E7 -1.24 -1.3177 -0.9497 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C16 mock treatment 8.4446424E7 -1.34E7 -1.16 8.6753361E7 -4530000.0 -0.4 -1.0986 -0.8983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C17 compound treatment 8.9568311E7 -8270000.0 -0.71 8.6231863E7 -5060000.0 -0.44 -0.8181 -0.9735 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C18 compound treatment 9.9792317E7 1950000.0 0.17 9.2935147E7 1650000.0 0.14 0.2212 0.997 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C19 compound treatment 9.8850884E7 1010000.0 0.09 8.4829559E7 -6460000.0 -0.57 -0.3379 -0.5909 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C20 compound treatment 8.999152E7 -7850000.0 -0.68 9.4497651E7 3210000.0 0.28 -0.2807 -0.3826 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C21 compound treatment 1.07136557E8 9300000.0 0.8 9.9626457E7 8340000.0 0.73 1.0838 0.9989 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C22 compound treatment 1.03349009E8 5510000.0 0.48 9.9881684E7 8590000.0 0.75 0.8683 0.9756 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C23 compound treatment 1.08288745E8 1.04E7 0.9 9.2275616E7 988000.0 0.09 0.6993 0.7713 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 C24 compound treatment 9.902575E7 1190000.0 0.1 1.05681957E8 1.44E7 1.26 0.9632 0.7621 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D01 compound treatment 1.01134063E8 3290000.0 0.28 1.02073826E8 1.08E7 0.94 0.8686 0.8811 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D02 compound treatment 1.01057551E8 3220000.0 0.28 9.6553719E7 5270000.0 0.46 0.5224 0.9707 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D03 compound treatment 1.00741245E8 2900000.0 0.25 9.6474244E7 5190000.0 0.45 0.4981 0.9608 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D04 compound treatment 8.8608697E7 -9230000.0 -0.8 8.2529193E7 -8760000.0 -0.77 -1.1058 -0.9998 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D05 compound treatment 9.4059168E7 -3780000.0 -0.33 9.4143481E7 2860000.0 0.25 -0.0542 -0.1318 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D06 compound treatment 9.1582011E7 -6260000.0 -0.54 9.3949535E7 2660000.0 0.23 -0.2175 -0.3695 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D07 compound treatment 9.6636585E7 -1200000.0 -0.1 9.7674043E7 6390000.0 0.56 0.3217 0.5659 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D08 compound treatment 9.0936607E7 -6900000.0 -0.6 7.9958732E7 -1.13E7 -0.99 -1.1227 -0.9704 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D09 compound treatment 8.2777101E7 -1.51E7 -1.3 8.9572568E7 -1720000.0 -0.15 -1.0261 -0.7835 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D10 compound treatment 8.8446168E7 -9390000.0 -0.81 8.5483358E7 -5800000.0 -0.51 -0.933 -0.9746 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D11 mock treatment 8.8609512E7 -9230000.0 -0.8 9.1351962E7 63900.0 0.01 -0.5598 -0.7021 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D12 mock treatment 8.1944555E7 -1.59E7 -1.37 7.8489462E7 -1.28E7 -1.12 -1.7628 -0.9949 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D13 compound treatment 8.0313415E7 -1.75E7 -1.51 9.0266787E7 -1020000.0 -0.09 -1.1336 -0.7476 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D14 compound treatment 8.419367E7 -1.36E7 -1.18 8.6025214E7 -5260000.0 -0.46 -1.1591 -0.916 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D15 mock treatment 9.3821489E7 -4020000.0 -0.35 8.26439E7 -8640000.0 -0.76 -0.7804 -0.9376 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D16 mock treatment 9.2428599E7 -5410000.0 -0.47 8.9308003E7 -1980000.0 -0.17 -0.453 -0.9088 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D17 compound treatment 8.4551221E7 -1.33E7 -1.15 9.2419491E7 1130000.0 0.1 -0.7416 -0.6437 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D18 compound treatment 9.2822305E7 -5020000.0 -0.43 9.3017081E7 1730000.0 0.15 -0.1995 -0.4345 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D19 compound treatment 1.00524029E8 2680000.0 0.23 8.967166E7 -1620000.0 -0.14 0.0639 0.2353 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D20 compound treatment 9.708352E7 -757000.0 -0.07 9.634221E7 5050000.0 0.44 0.2666 0.5962 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D21 compound treatment 9.4127656E7 -3710000.0 -0.32 1.02708395E8 1.14E7 1.0 0.48 0.4573 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D22 compound treatment 9.9403328E7 1560000.0 0.14 8.9078375E7 -2210000.0 -0.19 -0.0413 -0.175 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D23 compound treatment 1.09071905E8 1.12E7 0.97 1.04429023E8 1.31E7 1.15 1.4992 0.9964 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 D24 compound treatment 1.05023544E8 7180000.0 0.62 1.03938119E8 1.27E7 1.11 1.2216 0.9625 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E01 mock treatment 1.05296553E8 7460000.0 0.64 1.02714503E8 1.14E7 1.0 1.1625 0.9774 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E02 mock treatment 1.07420057E8 9580000.0 0.83 9.7933688E7 6650000.0 0.58 0.9963 0.9851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E03 compound treatment 1.02792398E8 4950000.0 0.43 9.7924151E7 6640000.0 0.58 0.7131 0.9887 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E04 compound treatment 9.6438732E7 -1400000.0 -0.12 9.2052498E7 764000.0 0.07 -0.0383 -0.2768 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E05 compound treatment 9.7145473E7 -695000.0 -0.06 9.37613E7 2470000.0 0.22 0.1106 0.4925 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E06 compound treatment 9.1255354E7 -6580000.0 -0.57 9.1084618E7 -203000.0 -0.02 -0.4148 -0.7289 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E07 compound treatment 9.5025228E7 -2810000.0 -0.24 8.9518144E7 -1770000.0 -0.15 -0.2814 -0.9763 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E08 compound treatment 8.8170704E7 -9670000.0 -0.84 8.9272063E7 -2020000.0 -0.18 -0.7153 -0.838 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E09 mock treatment 9.2978917E7 -4860000.0 -0.42 9.0479392E7 -809000.0 -0.07 -0.3469 -0.8148 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E10 mock treatment 8.8603388E7 -9240000.0 -0.8 8.40736E7 -7210000.0 -0.63 -1.0106 -0.9933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E11 compound treatment 8.9634107E7 -8210000.0 -0.71 8.4712272E7 -6580000.0 -0.58 -0.9081 -0.9947 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E12 compound treatment 8.3223194E7 -1.46E7 -1.26 8.4988514E7 -6300000.0 -0.55 -1.2826 -0.931 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E13 compound treatment 8.8586947E7 -9250000.0 -0.8 8.8095657E7 -3190000.0 -0.28 -0.7627 -0.9008 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E14 compound treatment 8.3148294E7 -1.47E7 -1.27 8.232877E7 -8960000.0 -0.78 -1.4517 -0.9732 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E15 compound treatment 9.2425823E7 -5410000.0 -0.47 8.8465497E7 -2820000.0 -0.25 -0.5053 -0.9555 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E16 compound treatment 8.9383269E7 -8460000.0 -0.73 8.6194717E7 -5090000.0 -0.45 -0.8317 -0.9719 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E17 mock treatment 1.01895376E8 4060000.0 0.35 9.4866791E7 3580000.0 0.31 0.4691 0.9984 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E18 mock treatment 1.03885303E8 6050000.0 0.52 9.6463347E7 5180000.0 0.45 0.6895 0.9975 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E19 compound treatment 9.6964952E7 -875000.0 -0.08 9.395753E7 2670000.0 0.23 0.1117 0.4551 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E20 compound treatment 9.4837773E7 -3000000.0 -0.26 9.3487827E7 2200000.0 0.19 -0.0472 -0.1463 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E21 compound treatment 1.02149859E8 4310000.0 0.37 9.8000589E7 6710000.0 0.59 0.6786 0.9758 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E22 compound treatment 1.00835293E8 3000000.0 0.26 9.6948575E7 5660000.0 0.5 0.5332 0.9541 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E23 compound treatment 1.0534616E8 7510000.0 0.65 9.8628247E7 7340000.0 0.64 0.9127 1.0 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 E24 compound treatment 1.04361327E8 6520000.0 0.56 9.9883028E7 8590000.0 0.75 0.9302 0.9898 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F01 mock treatment 1.0469808E8 6860000.0 0.59 1.00498717E8 9210000.0 0.81 0.9888 0.9885 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F02 mock treatment 1.02480515E8 4640000.0 0.4 9.6868518E7 5580000.0 0.49 0.6288 0.9952 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F03 compound treatment 1.00168102E8 2330000.0 0.2 9.7097906E7 5810000.0 0.51 0.5017 0.9176 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F04 compound treatment 9.2566601E7 -5270000.0 -0.46 9.2707538E7 1420000.0 0.12 -0.2342 -0.4961 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F05 compound treatment 9.4912335E7 -2930000.0 -0.25 9.5555205E7 4270000.0 0.37 0.0853 0.189 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F06 compound treatment 9.2755124E7 -5090000.0 -0.44 8.902632E7 -2260000.0 -0.2 -0.4505 -0.9352 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F07 compound treatment 9.0025309E7 -7810000.0 -0.67 9.3836729E7 2550000.0 0.22 -0.3196 -0.4495 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F08 compound treatment 9.0589269E7 -7250000.0 -0.63 8.6352816E7 -4940000.0 -0.43 -0.7483 -0.9835 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F09 mock treatment 9.2067913E7 -5770000.0 -0.5 8.9834272E7 -1450000.0 -0.13 -0.4425 -0.86 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F10 mock treatment 8.6909237E7 -1.09E7 -0.94 8.3671122E7 -7620000.0 -0.67 -1.139 -0.9855 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F11 compound treatment 9.0770599E7 -7070000.0 -0.61 9.1293134E7 5100.0 0.0 -0.4315 -0.7066 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F12 compound treatment 8.4437899E7 -1.34E7 -1.16 8.1752157E7 -9540000.0 -0.83 -1.4087 -0.9871 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F13 compound treatment 8.8835946E7 -9000000.0 -0.78 8.9774084E7 -1510000.0 -0.13 -0.6436 -0.8158 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F14 compound treatment 8.6750062E7 -1.11E7 -0.96 8.7932439E7 -3360000.0 -0.29 -0.885 -0.8833 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F15 compound treatment 9.3423151E7 -4420000.0 -0.38 9.244523E7 1160000.0 0.1 -0.1982 -0.502 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F16 compound treatment 9.0077017E7 -7760000.0 -0.67 8.8638162E7 -2650000.0 -0.23 -0.6381 -0.8994 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F17 mock treatment 1.01298261E8 3460000.0 0.3 1.00482144E8 9190000.0 0.8 0.7802 0.909 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F18 mock treatment 1.00589317E8 2750000.0 0.24 9.6293393E7 5010000.0 0.44 0.4777 0.9586 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F19 compound treatment 9.7077652E7 -763000.0 -0.07 9.6351059E7 5060000.0 0.44 0.2668 0.5955 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F20 compound treatment 9.5911296E7 -1930000.0 -0.17 9.5016103E7 3730000.0 0.33 0.1129 0.3082 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F21 compound treatment 1.01916868E8 4080000.0 0.35 1.00089467E8 8800000.0 0.77 0.7937 0.9371 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F22 compound treatment 9.6526193E7 -1310000.0 -0.11 9.4655203E7 3370000.0 0.29 0.1281 0.4057 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F23 compound treatment 1.02129269E8 4290000.0 0.37 9.9833429E7 8550000.0 0.75 0.7908 0.9475 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 F24 compound treatment 1.04242357E8 6400000.0 0.55 1.01311549E8 1.0E7 0.88 1.0113 0.9752 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G01 compound treatment 1.10384373E8 1.25E7 1.08 9.5235661E7 3950000.0 0.35 1.0104 0.8885 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G02 compound treatment 1.06788217E8 8950000.0 0.77 1.02474292E8 1.12E7 0.98 1.2388 0.9931 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G03 mock treatment 1.00305971E8 2470000.0 0.21 1.00409938E8 9120000.0 0.8 0.7151 0.8655 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G04 mock treatment 1.05018045E8 7180000.0 0.62 9.7095863E7 5810000.0 0.51 0.7978 0.9951 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G05 compound treatment 9.9166195E7 1330000.0 0.11 9.438767E7 3100000.0 0.27 0.2728 0.9265 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G06 compound treatment 9.8774867E7 935000.0 0.08 9.0291598E7 -996000.0 -0.09 -0.0046 -0.0385 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G07 compound treatment 9.6165173E7 -1670000.0 -0.14 8.8447295E7 -2840000.0 -0.25 -0.2781 -0.9668 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G08 compound treatment 9.6795653E7 -1040000.0 -0.09 8.9070057E7 -2220000.0 -0.19 -0.2011 -0.9393 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G09 compound treatment 9.6566283E7 -1270000.0 -0.11 9.0538451E7 -750000.0 -0.07 -0.1242 -0.9695 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G10 compound treatment 9.0351781E7 -7490000.0 -0.65 8.7064784E7 -4220000.0 -0.37 -0.7187 -0.9648 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G11 compound treatment 9.4001534E7 -3840000.0 -0.33 8.6421538E7 -4870000.0 -0.43 -0.5356 -0.9923 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G12 compound treatment 9.1814918E7 -6030000.0 -0.52 8.8877698E7 -2410000.0 -0.21 -0.5172 -0.9209 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G13 compound treatment 9.2693309E7 -5150000.0 -0.44 8.7405419E7 -3880000.0 -0.34 -0.5546 -0.9912 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G14 compound treatment 9.2254096E7 -5590000.0 -0.48 8.7081634E7 -4210000.0 -0.37 -0.6015 -0.9911 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G15 compound treatment 9.1126312E7 -6710000.0 -0.58 8.7871695E7 -3420000.0 -0.3 -0.6215 -0.9525 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G16 compound treatment 9.4406597E7 -3430000.0 -0.3 8.5891716E7 -5400000.0 -0.47 -0.5437 -0.9749 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G17 compound treatment 9.8868701E7 1030000.0 0.09 9.3894326E7 2610000.0 0.23 0.2241 0.9155 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G18 compound treatment 1.00151797E8 2310000.0 0.2 9.1788313E7 500000.0 0.04 0.1721 0.8422 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G19 mock treatment 1.01178957E8 3340000.0 0.29 9.5651285E7 4360000.0 0.38 0.4739 0.9904 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G20 mock treatment 9.9811931E7 1970000.0 0.17 9.4974203E7 3690000.0 0.32 0.3485 0.9554 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G21 compound treatment 1.0403457E8 6190000.0 0.54 9.6083431E7 4800000.0 0.42 0.6751 0.9928 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G22 compound treatment 1.02934548E8 5090000.0 0.44 9.6062666E7 4770000.0 0.42 0.6066 0.9997 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G23 compound treatment 1.07656766E8 9820000.0 0.85 1.02552406E8 1.13E7 0.99 1.2966 0.9972 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 G24 compound treatment 1.00983077E8 3140000.0 0.27 1.01344113E8 1.01E7 0.88 0.8143 0.8841 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H01 compound treatment 1.04386603E8 6550000.0 0.57 1.04302812E8 1.3E7 1.14 1.2052 0.9478 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H02 compound treatment 9.7415221E7 -425000.0 -0.04 9.2691113E7 1400000.0 0.12 0.0609 0.475 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H03 mock treatment 1.02319157E8 4480000.0 0.39 9.9153629E7 7870000.0 0.69 0.7603 0.9629 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H04 mock treatment 9.4895033E7 -2950000.0 -0.25 9.4310679E7 3020000.0 0.26 0.0072 0.0196 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H05 compound treatment 1.00198761E8 2360000.0 0.2 9.5749017E7 4460000.0 0.39 0.4201 0.954 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H06 compound treatment 9.5740823E7 -2100000.0 -0.18 9.2954905E7 1670000.0 0.15 -0.0251 -0.1077 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H07 compound treatment 9.6135467E7 -1700000.0 -0.15 9.7983824E7 6700000.0 0.59 0.3102 0.5135 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H08 compound treatment 9.0667475E7 -7170000.0 -0.62 8.4677343E7 -6610000.0 -0.58 -0.8472 -0.9994 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H09 compound treatment 9.7268043E7 -572000.0 -0.05 9.335287E7 2060000.0 0.18 0.0928 0.4956 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H10 compound treatment 9.0085303E7 -7750000.0 -0.67 8.6081898E7 -5210000.0 -0.46 -0.7958 -0.9824 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H11 compound treatment 9.4170276E7 -3670000.0 -0.32 9.2546243E7 1260000.0 0.11 -0.1463 -0.4359 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H12 compound treatment 9.1202448E7 -6640000.0 -0.57 8.7501308E7 -3790000.0 -0.33 -0.6397 -0.9661 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H13 compound treatment 9.6957323E7 -883000.0 -0.08 9.0472391E7 -816000.0 -0.07 -0.1044 -0.9995 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H14 compound treatment 8.7104328E7 -1.07E7 -0.93 8.4341851E7 -6950000.0 -0.61 -1.0855 -0.979 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H15 compound treatment 9.4359702E7 -3480000.0 -0.3 9.0023474E7 -1260000.0 -0.11 -0.2908 -0.9079 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H16 compound treatment 9.334117E7 -4500000.0 -0.39 8.7808927E7 -3480000.0 -0.3 -0.4901 -0.9927 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H17 compound treatment 9.9692977E7 1850000.0 0.16 9.7228281E7 5940000.0 0.52 0.4808 0.8838 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H18 compound treatment 9.492227E7 -2920000.0 -0.25 9.1198905E7 -89100.0 -0.01 -0.1837 -0.7286 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H19 mock treatment 1.02611887E8 4770000.0 0.41 9.5538694E7 4250000.0 0.37 0.5545 0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H20 mock treatment 1.00323274E8 2480000.0 0.21 9.477312E7 3490000.0 0.31 0.3673 0.9852 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H21 compound treatment 1.06794472E8 8950000.0 0.77 1.02464159E8 1.12E7 0.98 1.2385 0.9932 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H22 compound treatment 9.4750694E7 -3090000.0 -0.27 8.9581428E7 -1710000.0 -0.15 -0.2943 -0.9624 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H23 compound treatment 1.079312E8 1.01E7 0.87 1.03127477E8 1.18E7 1.04 1.349 0.9963 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 H24 compound treatment 1.07166528E8 9330000.0 0.81 9.8854302E7 7570000.0 0.66 1.0378 0.9953 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I01 compound treatment 1.14614259E8 1.68E7 1.45 1.00523888E8 9240000.0 0.81 1.596 0.962 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I02 compound treatment 1.02636489E8 4800000.0 0.41 9.6910851E7 5620000.0 0.49 0.6409 0.9963 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I03 compound treatment 1.05574818E8 7730000.0 0.67 9.6795618E7 5510000.0 0.48 0.8132 0.9872 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I04 compound treatment 9.931114E7 1470000.0 0.13 9.2815932E7 1530000.0 0.13 0.1844 0.9997 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I05 mock treatment 1.03159158E8 5320000.0 0.46 9.4878323E7 3590000.0 0.31 0.547 0.9828 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I06 mock treatment 9.6598875E7 -1240000.0 -0.11 8.8205398E7 -3080000.0 -0.27 -0.2666 -0.9183 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I07 compound treatment 9.9927611E7 2090000.0 0.18 9.0802558E7 -485000.0 -0.04 0.0974 0.5261 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I08 compound treatment 9.5653439E7 -2190000.0 -0.19 8.8775633E7 -2510000.0 -0.22 -0.289 -0.9971 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I09 compound treatment 9.7315733E7 -524000.0 -0.05 8.8962921E7 -2330000.0 -0.2 -0.1759 -0.8439 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I10 compound treatment 9.4340728E7 -3500000.0 -0.3 8.7821787E7 -3470000.0 -0.3 -0.4282 -1.0 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I11 compound treatment 9.6839287E7 -1000000.0 -0.09 8.9016017E7 -2270000.0 -0.2 -0.2017 -0.9304 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I12 compound treatment 9.2701133E7 -5140000.0 -0.44 8.5279303E7 -6010000.0 -0.53 -0.6857 -0.9964 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I13 compound treatment 9.8855415E7 1020000.0 0.09 8.9472425E7 -1820000.0 -0.16 -0.0504 -0.2774 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I14 compound treatment 9.687403E7 -966000.0 -0.08 8.8443832E7 -2840000.0 -0.25 -0.235 -0.8952 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I15 compound treatment 9.7981058E7 141000.0 0.01 8.830814E7 -2980000.0 -0.26 -0.1758 -0.6734 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I16 compound treatment 9.2360024E7 -5480000.0 -0.47 8.7311735E7 -3980000.0 -0.35 -0.5808 -0.9886 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I17 compound treatment 9.8494493E7 654000.0 0.06 9.0759506E7 -529000.0 -0.05 0.0073 0.0993 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I18 compound treatment 9.6121463E7 -1720000.0 -0.15 8.9753498E7 -1530000.0 -0.13 -0.1999 -0.9988 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I19 compound treatment 1.01141004E8 3300000.0 0.29 9.2818287E7 1530000.0 0.13 0.2963 0.9407 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I20 compound treatment 9.945551E7 1620000.0 0.14 9.4941442E7 3650000.0 0.32 0.3247 0.9309 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I21 mock treatment 9.977468E7 1930000.0 0.17 9.5274726E7 3990000.0 0.35 0.3649 0.9432 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I22 mock treatment 9.8773705E7 934000.0 0.08 9.5402081E7 4110000.0 0.36 0.3116 0.8445 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I23 compound treatment 1.02559852E8 4720000.0 0.41 9.895062E7 7660000.0 0.67 0.7624 0.9715 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 I24 compound treatment 1.05780908E8 7940000.0 0.69 1.02045509E8 1.08E7 0.94 1.1507 0.9879 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J01 compound treatment 1.08390693E8 1.06E7 0.91 1.02305586E8 1.1E7 0.96 1.3262 0.9996 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J02 compound treatment 1.03107965E8 5270000.0 0.45 9.7777741E7 6490000.0 0.57 0.7233 0.994 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J03 compound treatment 1.03748125E8 5910000.0 0.51 9.8579772E7 7290000.0 0.64 0.8121 0.9939 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J04 compound treatment 9.4421699E7 -3420000.0 -0.3 9.0925376E7 -363000.0 -0.03 -0.2312 -0.7786 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J05 mock treatment 9.8914352E7 1070000.0 0.09 9.6398582E7 5110000.0 0.45 0.3819 0.836 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J06 mock treatment 9.244735E7 -5390000.0 -0.47 8.8619332E7 -2670000.0 -0.23 -0.4945 -0.949 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J07 compound treatment 9.9036918E7 1200000.0 0.1 9.7392281E7 6100000.0 0.53 0.4508 0.8286 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J08 compound treatment 9.1570248E7 -6270000.0 -0.54 8.5193771E7 -6090000.0 -0.53 -0.7601 -1.0 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J09 compound treatment 9.6592238E7 -1250000.0 -0.11 9.3611332E7 2320000.0 0.2 0.0676 0.2936 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J10 compound treatment 9.2185594E7 -5650000.0 -0.49 8.4459961E7 -6830000.0 -0.6 -0.7679 -0.995 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J11 compound treatment 9.6851019E7 -989000.0 -0.09 8.9139959E7 -2150000.0 -0.19 -0.1933 -0.9363 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J12 compound treatment 9.0528254E7 -7310000.0 -0.63 8.4818961E7 -6470000.0 -0.57 -0.8469 -0.9985 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J13 compound treatment 9.8399333E7 559000.0 0.05 8.4643001E7 -6650000.0 -0.58 -0.3771 -0.6462 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J14 compound treatment 8.919095E7 -8650000.0 -0.75 8.8216165E7 -3070000.0 -0.27 -0.7183 -0.9048 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J15 compound treatment 1.0014927E8 2310000.0 0.2 9.2148701E7 861000.0 0.08 0.1943 0.9113 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J16 compound treatment 9.0438379E7 -7400000.0 -0.64 8.4132978E7 -7160000.0 -0.63 -0.8948 -0.9999 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J17 compound treatment 1.01467052E8 3630000.0 0.31 9.3547388E7 2260000.0 0.2 0.3613 0.9754 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J18 compound treatment 9.3556723E7 -4280000.0 -0.37 8.7030853E7 -4260000.0 -0.37 -0.5251 -1.0 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J19 compound treatment 1.00998312E8 3160000.0 0.27 9.659823E7 5310000.0 0.46 0.5215 0.9678 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J20 compound treatment 9.6367788E7 -1470000.0 -0.13 9.1201686E7 -86400.0 -0.01 -0.0953 -0.7478 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J21 mock treatment 1.0481955E8 6980000.0 0.6 9.6068379E7 4780000.0 0.42 0.7221 0.9841 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J22 mock treatment 9.8583288E7 743000.0 0.06 9.5043693E7 3760000.0 0.33 0.2778 0.8295 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J23 compound treatment 1.09409125E8 1.16E7 1.0 1.03511194E8 1.22E7 1.07 1.463 0.9994 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 J24 compound treatment 1.05654357E8 7810000.0 0.67 1.00096798E8 8810000.0 0.77 1.0224 0.9978 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K01 compound treatment 1.14281807E8 1.64E7 1.42 1.00785449E8 9500000.0 0.83 1.5919 0.9674 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K02 compound treatment 8.5068444E7 -1.28E7 -1.1 9.5787573E7 4500000.0 0.39 -0.5016 -0.4282 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K03 compound treatment 8.0559253E7 -1.73E7 -1.49 9.8953798E7 7670000.0 0.67 -0.581 -0.3551 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K04 compound treatment 7.9361303E7 -1.85E7 -1.6 8.8754053E7 -2530000.0 -0.22 -1.2854 -0.7977 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K05 compound treatment 1.01641655E8 3800000.0 0.33 1.0056099E8 9270000.0 0.81 0.806 0.9207 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K06 compound treatment 1.00732151E8 2890000.0 0.25 9.4603605E7 3320000.0 0.29 0.3818 0.9972 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K07 mock treatment 9.954366E7 1700000.0 0.15 9.5436198E7 4150000.0 0.36 0.3607 0.9209 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K08 mock treatment 9.6211648E7 -1630000.0 -0.14 8.6326552E7 -4960000.0 -0.43 -0.4065 -0.8906 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K09 compound treatment 9.7821284E7 -18900.0 0.0 9.2070699E7 783000.0 0.07 0.0473 0.6901 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K10 compound treatment 9.620483E7 -1640000.0 -0.14 8.7401108E7 -3890000.0 -0.34 -0.3404 -0.9242 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K11 compound treatment 9.7978111E7 138000.0 0.01 9.2163257E7 875000.0 0.08 0.0626 0.8074 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K12 compound treatment 9.1644238E7 -6200000.0 -0.54 8.310179E7 -8190000.0 -0.72 -0.885 -0.9897 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K13 compound treatment 1.01483629E8 3640000.0 0.31 9.4929824E7 3640000.0 0.32 0.4479 1.0 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K14 compound treatment 9.4474923E7 -3370000.0 -0.29 9.0709266E7 -579000.0 -0.05 -0.2413 -0.818 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K15 mock treatment 1.00298999E8 2460000.0 0.21 8.2329602E7 -8960000.0 -0.78 -0.4042 -0.4976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K16 mock treatment 1.00391273E8 2550000.0 0.22 8.6236582E7 -5050000.0 -0.44 -0.1568 -0.3174 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K17 compound treatment 1.00064496E8 2220000.0 0.19 9.7192759E7 5900000.0 0.52 0.5013 0.9092 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K18 compound treatment 9.890985E7 1070000.0 0.09 9.1604071E7 316000.0 0.03 0.0849 0.8802 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K19 compound treatment 1.05242483E8 7400000.0 0.64 9.440201E7 3110000.0 0.27 0.6448 0.9277 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K20 compound treatment 9.7509486E7 -331000.0 -0.03 9.9833666E7 8550000.0 0.75 0.5086 0.6796 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K21 compound treatment 1.04929573E8 7090000.0 0.61 1.00047279E8 8760000.0 0.77 0.975 0.9938 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K22 compound treatment 1.05356903E8 7520000.0 0.65 9.4829452E7 3540000.0 0.31 0.6782 0.9428 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K23 mock treatment 1.02779094E8 4940000.0 0.43 1.03516099E8 1.22E7 1.07 1.0584 0.9187 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 K24 mock treatment 1.10918197E8 1.31E7 1.13 9.8226997E7 6940000.0 0.61 1.2281 0.9576 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L01 compound treatment 9.7343333E7 -497000.0 -0.04 1.03071491E8 1.18E7 1.03 0.6989 0.6771 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L02 compound treatment 9.6280459E7 -1560000.0 -0.13 9.6998511E7 5710000.0 0.5 0.2581 0.4987 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L03 compound treatment 7.8961177E7 -1.89E7 -1.63 9.569203E7 4400000.0 0.39 -0.8805 -0.5255 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L04 compound treatment 7.7266269E7 -2.06E7 -1.78 9.2031715E7 744000.0 0.07 -1.2105 -0.6808 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L05 compound treatment 1.02982991E8 5140000.0 0.44 1.01720314E8 1.04E7 0.91 0.9597 0.9452 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L06 compound treatment 9.6934011E7 -906000.0 -0.08 8.9068641E7 -2220000.0 -0.19 -0.1927 -0.9201 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L07 mock treatment 9.5016346E7 -2820000.0 -0.24 9.6108464E7 4820000.0 0.42 0.1258 0.2582 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L08 mock treatment 9.4211553E7 -3630000.0 -0.31 8.9417486E7 -1870000.0 -0.16 -0.3374 -0.9541 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L09 compound treatment 1.00961777E8 3120000.0 0.27 9.2810538E7 1520000.0 0.13 0.2849 0.9472 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L10 compound treatment 9.4953566E7 -2890000.0 -0.25 8.7916494E7 -3370000.0 -0.3 -0.3849 -0.9965 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L11 compound treatment 9.6117802E7 -1720000.0 -0.15 9.5952205E7 4660000.0 0.41 0.1834 0.4222 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L12 compound treatment 9.76368E7 -203000.0 -0.02 8.8573578E7 -2710000.0 -0.24 -0.1804 -0.7573 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L13 compound treatment 9.1949562E7 -5890000.0 -0.51 8.6848101E7 -4440000.0 -0.39 -0.6345 -0.9911 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L14 compound treatment 9.6814869E7 -1030000.0 -0.09 8.7180738E7 -4110000.0 -0.36 -0.3168 -0.8557 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L15 mock treatment 9.9121657E7 1280000.0 0.11 8.3913557E7 -7370000.0 -0.65 -0.3781 -0.5774 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L16 mock treatment 9.8162893E7 323000.0 0.03 7.8978164E7 -1.23E7 -1.08 -0.7421 -0.6886 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L17 compound treatment 1.01112062E8 3270000.0 0.28 9.486626E7 3580000.0 0.31 0.4213 0.9987 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L18 compound treatment 1.00040527E8 2200000.0 0.19 9.2729179E7 1440000.0 0.13 0.2236 0.9802 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L19 compound treatment 1.00869486E8 3030000.0 0.26 9.803512E7 6750000.0 0.59 0.6026 0.9329 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L20 compound treatment 1.01320777E8 3480000.0 0.3 9.5093752E7 3810000.0 0.33 0.4481 0.9987 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L21 compound treatment 9.6342156E7 -1500000.0 -0.13 1.00955984E8 9670000.0 0.85 0.5068 0.5921 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L22 compound treatment 9.9750311E7 1910000.0 0.16 9.3432795E7 2140000.0 0.19 0.2494 0.9979 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L23 mock treatment 1.11675398E8 1.38E7 1.19 1.02907883E8 1.16E7 1.02 1.5641 0.9968 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 L24 mock treatment 1.06403914E8 8560000.0 0.74 1.03160367E8 1.19E7 1.04 1.2577 0.9861 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M01 compound treatment 1.04952676E8 7110000.0 0.61 1.04774005E8 1.35E7 1.18 1.269 0.9537 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M02 compound treatment 1.05418403E8 7580000.0 0.65 1.00712173E8 9420000.0 0.82 1.046 0.9934 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M03 compound treatment 1.0624233E8 8400000.0 0.73 9.3566262E7 2280000.0 0.2 0.6541 0.8692 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M04 compound treatment 9.4450057E7 -3390000.0 -0.29 9.2391173E7 1100000.0 0.1 -0.1388 -0.4501 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M05 compound treatment 1.06024274E8 8180000.0 0.71 9.9052914E7 7760000.0 0.68 0.9804 0.9998 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M06 compound treatment 1.03722005E8 5880000.0 0.51 8.6048234E7 -5240000.0 -0.46 0.035 0.0511 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M07 compound treatment 9.4542849E7 -3300000.0 -0.28 9.4974333E7 3690000.0 0.32 0.0267 0.0621 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M08 compound treatment 9.7705659E7 -135000.0 -0.01 8.6749939E7 -4540000.0 -0.4 -0.2891 -0.7275 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M09 mock treatment 1.01336548E8 3500000.0 0.3 8.4493295E7 -6790000.0 -0.59 -0.2069 -0.3103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M10 mock treatment 9.1310869E7 -6530000.0 -0.56 8.9612674E7 -1680000.0 -0.15 -0.5025 -0.8623 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M11 compound treatment 7.7591995E7 -2.02E7 -1.75 7.0742603E7 -2.05E7 -1.8 -2.5081 -0.9999 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M12 compound treatment 8.0232184E7 -1.76E7 -1.52 7.2899742E7 -1.84E7 -1.61 -2.2133 -0.9996 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M13 mock treatment 9.235909E7 -5480000.0 -0.47 9.3195762E7 1910000.0 0.17 -0.2167 -0.4317 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M14 mock treatment 9.8530984E7 691000.0 0.06 8.7782975E7 -3510000.0 -0.31 -0.1747 -0.5591 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M15 compound treatment 9.2323535E7 -5520000.0 -0.48 8.3062625E7 -8230000.0 -0.72 -0.8459 -0.9799 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M16 compound treatment 9.9323339E7 1480000.0 0.13 8.8601187E7 -2690000.0 -0.24 -0.0757 -0.2827 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M17 compound treatment 9.6766967E7 -1070000.0 -0.09 8.9507482E7 -1780000.0 -0.16 -0.1757 -0.9692 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M18 compound treatment 9.9334389E7 1490000.0 0.13 8.490012E7 -6390000.0 -0.56 -0.3041 -0.5299 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M19 compound treatment 9.433158E7 -3510000.0 -0.3 9.4221431E7 2930000.0 0.26 -0.0328 -0.0825 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M20 compound treatment 1.03477984E8 5640000.0 0.49 9.4373228E7 3090000.0 0.27 0.5353 0.9613 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M21 compound treatment 1.04175442E8 6340000.0 0.55 8.4310534E7 -6980000.0 -0.61 -0.0449 -0.0547 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M22 compound treatment 9.6445514E7 -1390000.0 -0.12 9.6853869E7 5570000.0 0.49 0.2593 0.5167 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M23 compound treatment 1.06946256E8 9110000.0 0.79 1.04049655E8 1.28E7 1.12 1.3459 0.9853 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 M24 compound treatment 1.09297661E8 1.15E7 0.99 8.7452105E7 -3840000.0 -0.34 0.4624 0.4425 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N01 compound treatment 1.11121855E8 1.33E7 1.15 9.1016594E7 -271000.0 -0.02 0.7944 0.6923 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N02 compound treatment 1.03079972E8 5240000.0 0.45 9.8672726E7 7380000.0 0.65 0.777 0.9848 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N03 compound treatment 1.01180426E8 3340000.0 0.29 1.00894545E8 9610000.0 0.84 0.7985 0.8983 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N04 compound treatment 1.0246424E8 4620000.0 0.4 8.6157638E7 -5130000.0 -0.45 -0.0351 -0.0584 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N05 compound treatment 1.04799774E8 6960000.0 0.6 9.2518228E7 1230000.0 0.11 0.5012 0.8207 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N06 compound treatment 9.101698E7 -6820000.0 -0.59 9.3616711E7 2330000.0 0.2 -0.2726 -0.4372 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N07 compound treatment 1.06357266E8 8520000.0 0.74 8.6665815E7 -4620000.0 -0.4 0.2341 0.2789 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N08 compound treatment 9.5771717E7 -2070000.0 -0.18 8.511688E7 -6170000.0 -0.54 -0.5082 -0.8934 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N09 mock treatment 9.4198805E7 -3640000.0 -0.31 9.326532E7 1980000.0 0.17 -0.1 -0.2787 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N10 mock treatment 9.3301429E7 -4540000.0 -0.39 8.2033999E7 -9250000.0 -0.81 -0.8499 -0.9445 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N11 compound treatment 8.1642394E7 -1.62E7 -1.4 7.940372E7 -1.19E7 -1.04 -1.7247 -0.9893 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N12 compound treatment 7.3701572E7 -2.41E7 -2.08 7.494882E7 -1.63E7 -1.43 -2.4854 -0.9831 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N13 mock treatment 1.01361206E8 3520000.0 0.3 8.3590476E7 -7700000.0 -0.67 -0.2613 -0.3535 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N14 mock treatment 9.7270758E7 -569000.0 -0.05 9.0780206E7 -508000.0 -0.04 -0.0662 -0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N15 compound treatment 9.005076E7 -7790000.0 -0.67 9.0681924E7 -606000.0 -0.05 -0.5132 -0.7605 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N16 compound treatment 9.8398047E7 558000.0 0.05 8.4718264E7 -6570000.0 -0.57 -0.3725 -0.6456 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N17 compound treatment 1.06481407E8 8640000.0 0.75 9.4429116E7 3140000.0 0.27 0.7221 0.9079 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N18 compound treatment 9.2458334E7 -5380000.0 -0.46 8.7151556E7 -4140000.0 -0.36 -0.5847 -0.9924 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N19 compound treatment 1.07462429E8 9620000.0 0.83 8.8003343E7 -3280000.0 -0.29 0.3844 0.4371 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N20 compound treatment 9.9267153E7 1430000.0 0.12 8.9932173E7 -1360000.0 -0.12 0.0032 0.019 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N21 compound treatment 8.1831534E7 -1.6E7 -1.38 9.8217348E7 6930000.0 0.61 -0.5489 -0.3635 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N22 compound treatment 1.03191652E8 5350000.0 0.46 8.435457E7 -6930000.0 -0.61 -0.1022 -0.134 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N23 compound treatment 1.09681702E8 1.18E7 1.02 1.00576296E8 9290000.0 0.81 1.298 0.9935 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 N24 compound treatment 9.7818165E7 -22000.0 0.0 1.01086027E8 9800000.0 0.86 0.605 0.7055 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O01 compound treatment 1.1593798E8 1.81E7 1.56 9.8401038E7 7110000.0 0.62 1.5455 0.9185 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O02 compound treatment 1.02217508E8 4380000.0 0.38 1.00413811E8 9130000.0 0.8 0.8321 0.9417 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O03 compound treatment 1.11728813E8 1.39E7 1.2 1.03586027E8 1.23E7 1.08 1.6093 0.9985 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O04 compound treatment 1.01588753E8 3750000.0 0.32 9.2361034E7 1070000.0 0.09 0.2953 0.8761 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O05 compound treatment 1.05587388E8 7750000.0 0.67 9.9612823E7 8320000.0 0.73 0.9883 0.9991 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O06 compound treatment 1.04384931E8 6540000.0 0.57 9.4444069E7 3160000.0 0.28 0.595 0.9458 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O07 compound treatment 1.04869486E8 7030000.0 0.61 9.5010407E7 3720000.0 0.33 0.6597 0.9574 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O08 compound treatment 1.01225521E8 3390000.0 0.29 9.1120136E7 -168000.0 -0.01 0.1964 0.6707 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O09 compound treatment 1.01011085E8 3170000.0 0.27 9.2059363E7 771000.0 0.07 0.2414 0.8558 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O10 compound treatment 9.7077659E7 -763000.0 -0.07 8.7822184E7 -3470000.0 -0.3 -0.2611 -0.841 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O11 mock treatment 1.01041612E8 3200000.0 0.28 9.2881243E7 1590000.0 0.14 0.2941 0.9498 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O12 mock treatment 9.6427588E7 -1410000.0 -0.12 8.7431492E7 -3860000.0 -0.34 -0.3249 -0.9054 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O13 compound treatment 1.00655827E8 2820000.0 0.24 8.2029384E7 -9260000.0 -0.81 -0.401 -0.474 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O14 compound treatment 9.689333E7 -947000.0 -0.08 8.0595417E7 -1.07E7 -0.94 -0.7195 -0.766 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O15 compound treatment 1.00603973E8 2760000.0 0.24 9.3190988E7 1900000.0 0.17 0.2866 0.9845 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O16 compound treatment 9.5635013E7 -2210000.0 -0.19 9.0094817E7 -1190000.0 -0.1 -0.2085 -0.96 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O17 compound treatment 1.03193964E8 5350000.0 0.46 9.6879305E7 5590000.0 0.49 0.673 0.9996 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O18 compound treatment 9.8412413E7 572000.0 0.05 9.5248859E7 3960000.0 0.35 0.2801 0.7998 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O19 compound treatment 1.04919585E8 7080000.0 0.61 9.7785618E7 6500000.0 0.57 0.8345 0.9993 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O20 compound treatment 1.00945704E8 3110000.0 0.27 9.6559808E7 5270000.0 0.46 0.5159 0.9667 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O21 compound treatment 1.03906389E8 6070000.0 0.52 9.9675979E7 8390000.0 0.73 0.8896 0.9863 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O22 compound treatment 1.04795165E8 6950000.0 0.6 1.00415447E8 9130000.0 0.8 0.9896 0.9901 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O23 compound treatment 1.06893396E8 9050000.0 0.78 9.8087219E7 6800000.0 0.6 0.9737 0.9909 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 O24 compound treatment 1.05647851E8 7810000.0 0.67 9.970972E7 8420000.0 0.74 0.998 0.999 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P01 compound treatment 1.08356965E8 1.05E7 0.91 9.6619905E7 5330000.0 0.47 0.9723 0.9521 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P02 compound treatment 9.9822133E7 1980000.0 0.17 8.9611654E7 -1680000.0 -0.15 0.0173 0.0768 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P03 compound treatment 1.07163302E8 9320000.0 0.81 9.2603183E7 1320000.0 0.12 0.6508 0.8 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P04 compound treatment 1.03265325E8 5430000.0 0.47 9.6703548E7 5420000.0 0.47 0.6665 1.0 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P05 compound treatment 1.0718515E8 9340000.0 0.81 1.01572086E8 1.03E7 0.9 1.2072 0.9985 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P06 compound treatment 9.9419243E7 1580000.0 0.14 9.3310583E7 2020000.0 0.18 0.2216 0.9917 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P07 compound treatment 1.03658428E8 5820000.0 0.5 9.6889268E7 5600000.0 0.49 0.702 0.9999 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P08 compound treatment 9.6820978E7 -1020000.0 -0.09 9.0977327E7 -311000.0 -0.03 -0.0815 -0.8843 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P09 compound treatment 1.02865399E8 5030000.0 0.43 9.9714095E7 8430000.0 0.74 0.8284 0.9681 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P10 compound treatment 9.7287515E7 -553000.0 -0.05 9.143401E7 146000.0 0.01 -0.0247 -0.5003 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P11 mock treatment 1.00387679E8 2550000.0 0.22 9.3035894E7 1750000.0 0.15 0.2638 0.9842 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P12 mock treatment 9.8510463E7 670000.0 0.06 9.1274465E7 -13600.0 0.0 0.0401 0.6925 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P13 compound treatment 9.9859284E7 2020000.0 0.17 9.3195053E7 1910000.0 0.17 0.2413 0.9998 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P14 compound treatment 9.6910748E7 -929000.0 -0.08 8.8607262E7 -2680000.0 -0.23 -0.2227 -0.8979 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P15 compound treatment 1.02954412E8 5110000.0 0.44 9.308344E7 1800000.0 0.16 0.4235 0.9032 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P16 compound treatment 9.8087561E7 247000.0 0.02 9.3458584E7 2170000.0 0.19 0.1494 0.7817 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P17 compound treatment 1.06789274E8 8950000.0 0.77 9.7481992E7 6190000.0 0.54 0.9299 0.9849 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P18 compound treatment 1.00120529E8 2280000.0 0.2 9.5356437E7 4070000.0 0.36 0.391 0.961 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P19 compound treatment 1.06125159E8 8280000.0 0.72 9.9592339E7 8300000.0 0.73 1.0199 1.0 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P20 compound treatment 1.02929194E8 5090000.0 0.44 9.6374219E7 5090000.0 0.45 0.6256 1.0 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P21 compound treatment 1.03863835E8 6020000.0 0.52 9.9473344E7 8190000.0 0.72 0.8744 0.9877 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P22 compound treatment 1.02741777E8 4900000.0 0.42 9.9178014E7 7890000.0 0.69 0.7876 0.9724 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P23 compound treatment 1.06474208E8 8630000.0 0.75 1.04213722E8 1.29E7 1.13 1.3272 0.9796 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2101 P24 compound treatment 1.08673204E8 1.08E7 0.94 1.03350895E8 1.21E7 1.06 1.4081 0.9982 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A01 compound treatment 8.7049926E7 -1.0E7 -0.86 8.5668961E7 -6670000.0 -0.58 -1.0243 -0.9817 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A02 compound treatment 5.8168248E7 -3.89E7 -3.36 8.0394293E7 -1.19E7 -1.05 -3.1146 -0.8852 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A03 compound treatment 6.2935312E7 -3.41E7 -2.95 4.941954E7 -4.29E7 -3.76 -4.7403 -0.9928 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A04 compound treatment 5.1711351E7 -4.54E7 -3.92 4.0304456E7 -5.2E7 -4.55 -5.9899 -0.9972 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A05 compound treatment 9.1242358E7 -5820000.0 -0.5 9.9540239E7 7200000.0 0.63 0.0902 0.1118 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A06 compound treatment 3.8481078E7 -5.86E7 -5.06 5.4160316E7 -3.82E7 -3.34 -5.9405 -0.9797 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A07 compound treatment 3.2230773E7 -6.48E7 -5.6 2.1052153E7 -7.13E7 -6.24 -8.3711 -0.9985 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A08 compound treatment 5.4037019E7 -4.3E7 -3.72 5.1512093E7 -4.08E7 -3.57 -5.1543 -0.9998 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A09 compound treatment 7.813949E7 -1.89E7 -1.63 7.9203059E7 -1.31E7 -1.15 -1.9686 -0.9852 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A10 compound treatment 7.9080092E7 -1.8E7 -1.55 6.9547232E7 -2.28E7 -1.99 -2.5087 -0.9924 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A11 compound treatment 7.3881048E7 -2.32E7 -2.0 6.6153355E7 -2.62E7 -2.29 -3.0363 -0.9977 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A12 compound treatment 7.3439911E7 -2.36E7 -2.04 6.3857081E7 -2.85E7 -2.49 -3.2053 -0.9951 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A13 mock treatment 8.0637326E7 -1.64E7 -1.42 8.4550684E7 -7790000.0 -0.68 -1.4851 -0.9435 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A14 mock treatment 9.2386908E7 -4680000.0 -0.4 7.4892905E7 -1.74E7 -1.53 -1.3652 -0.8645 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A15 compound treatment 2.1286717E7 -7.58E7 -6.55 2.1384728E7 -7.1E7 -6.21 -9.0189 -0.9997 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A16 compound treatment 3.9310816E7 -5.78E7 -4.99 3.8899101E7 -5.34E7 -4.68 -6.8342 -0.9995 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A17 compound treatment 3.0898089E7 -6.62E7 -5.71 2.3166451E7 -6.92E7 -6.05 -8.3217 -0.9996 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A18 compound treatment 2.1328184E7 -7.57E7 -6.54 3.7488792E7 -5.48E7 -4.8 -8.0198 -0.9884 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A19 compound treatment 2.262187E7 -7.44E7 -6.43 2.2308709E7 -7.0E7 -6.13 -8.8802 -0.9997 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A20 compound treatment 2.3534866E7 -7.35E7 -6.35 4.8861264E7 -4.35E7 -3.8 -7.1813 -0.97 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A21 compound treatment 7.8121783E7 -1.89E7 -1.64 8.4139068E7 -8200000.0 -0.72 -1.6642 -0.9316 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A22 compound treatment 2.1410954E7 -7.57E7 -6.53 5.851301E7 -3.38E7 -2.96 -6.7137 -0.9359 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A23 compound treatment 9.6054411E7 -1010000.0 -0.09 8.1706025E7 -1.06E7 -0.93 -0.7196 -0.77 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 A24 compound treatment 9.6469949E7 -594000.0 -0.05 8.702518E7 -5310000.0 -0.46 -0.365 -0.7804 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B01 compound treatment 8.0930098E7 -1.61E7 -1.39 7.6031376E7 -1.63E7 -1.43 -1.9945 -0.9999 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B02 compound treatment 6.3494463E7 -3.36E7 -2.9 6.1772439E7 -3.06E7 -2.67 -3.9417 -0.9992 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B03 compound treatment 9.5682693E7 -1380000.0 -0.12 8.4606926E7 -7730000.0 -0.68 -0.5628 -0.8192 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B04 compound treatment 8.7093289E7 -9970000.0 -0.86 7.9885412E7 -1.25E7 -1.09 -1.3796 -0.9932 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B05 compound treatment 7.0370758E7 -2.67E7 -2.31 7.3061883E7 -1.93E7 -1.69 -2.8231 -0.9882 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B06 compound treatment 7.5419595E7 -2.16E7 -1.87 7.3050727E7 -1.93E7 -1.69 -2.5155 -0.9987 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B07 compound treatment 8.0160992E7 -1.69E7 -1.46 7.7628367E7 -1.47E7 -1.29 -1.9426 -0.998 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B08 compound treatment 7.7560248E7 -1.95E7 -1.68 7.4951617E7 -1.74E7 -1.52 -2.2671 -0.9987 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B09 compound treatment 6.2942359E7 -3.41E7 -2.95 6.8662546E7 -2.37E7 -2.07 -3.5491 -0.9851 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B10 compound treatment 7.841451E7 -1.86E7 -1.61 7.5650964E7 -1.67E7 -1.46 -2.1716 -0.9988 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B11 compound treatment 8.6463419E7 -1.06E7 -0.92 7.6787682E7 -1.55E7 -1.36 -1.6097 -0.9814 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B12 compound treatment 6.7817847E7 -2.92E7 -2.53 7.1333496E7 -2.1E7 -1.84 -3.086 -0.9878 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B13 mock treatment 8.7241238E7 -9820000.0 -0.85 9.0965956E7 -1370000.0 -0.12 -0.6848 -0.7992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B14 mock treatment 8.7514546E7 -9550000.0 -0.82 8.2135428E7 -1.02E7 -0.89 -1.2146 -0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B15 compound treatment 7.6942541E7 -2.01E7 -1.74 7.6513256E7 -1.58E7 -1.38 -2.2082 -0.9937 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B16 compound treatment 6.6046291E7 -3.1E7 -2.68 6.6550698E7 -2.58E7 -2.26 -3.4902 -0.9964 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B17 compound treatment 8.3617333E7 -1.34E7 -1.16 8.7278278E7 -5060000.0 -0.44 -1.1343 -0.9126 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B18 compound treatment 6.7581235E7 -2.95E7 -2.55 6.8964365E7 -2.34E7 -2.05 -3.2471 -0.9941 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B19 compound treatment 9.0065477E7 -7000000.0 -0.6 8.9298089E7 -3040000.0 -0.27 -0.6155 -0.932 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B20 compound treatment 6.589516E7 -3.12E7 -2.69 6.3293821E7 -2.9E7 -2.54 -3.701 -0.9996 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B21 compound treatment 6.2389494E7 -3.47E7 -2.99 7.3349528E7 -1.9E7 -1.66 -3.2928 -0.9614 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B22 compound treatment 7.7117843E7 -1.99E7 -1.72 7.6165649E7 -1.62E7 -1.42 -2.219 -0.9952 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B23 compound treatment 8.325201E7 -1.38E7 -1.19 8.8048087E7 -4290000.0 -0.38 -1.109 -0.8867 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 B24 compound treatment 7.484621E7 -2.22E7 -1.92 7.2874136E7 -1.95E7 -1.7 -2.5614 -0.9982 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C01 compound treatment 1.04383915E8 7320000.0 0.63 9.0203144E7 -2130000.0 -0.19 0.315 0.4778 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C02 compound treatment 9.1874151E7 -5190000.0 -0.45 8.6849011E7 -5490000.0 -0.48 -0.6566 -0.9994 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C03 compound treatment 7.794428E7 -1.91E7 -1.65 7.1683471E7 -2.07E7 -1.81 -2.4459 -0.999 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C04 compound treatment 8.6243016E7 -1.08E7 -0.93 8.9996793E7 -2340000.0 -0.2 -0.8057 -0.8421 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C05 compound treatment 9.5760719E7 -1300000.0 -0.11 8.4454479E7 -7880000.0 -0.69 -0.5674 -0.8118 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C06 compound treatment 2.0684246E7 -7.64E7 -6.6 2.0484877E7 -7.19E7 -6.29 -9.1114 -0.9997 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C07 compound treatment 8.1014567E7 -1.6E7 -1.39 7.8649876E7 -1.37E7 -1.2 -1.8273 -0.9974 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C08 compound treatment 5.9771011E7 -3.73E7 -3.22 6.0625969E7 -3.17E7 -2.78 -4.2401 -0.9972 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C09 compound treatment 2.0470717E7 -7.66E7 -6.62 1.9908931E7 -7.24E7 -6.34 -9.1601 -0.9998 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C10 compound treatment 7.7496252E7 -1.96E7 -1.69 7.912587E7 -1.32E7 -1.16 -2.0127 -0.9829 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C11 mock treatment 8.7994146E7 -9070000.0 -0.78 8.8833682E7 -3500000.0 -0.31 -0.7708 -0.9162 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C12 mock treatment 7.5881379E7 -2.12E7 -1.83 8.4028054E7 -8310000.0 -0.73 -1.8079 -0.9183 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C13 compound treatment 7.7552208E7 -1.95E7 -1.69 7.3734375E7 -1.86E7 -1.63 -2.3429 -0.9999 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C14 compound treatment 2.3198557E7 -7.39E7 -6.38 2.394165E7 -6.84E7 -5.99 -8.7439 -0.9995 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C15 mock treatment 8.8864233E7 -8200000.0 -0.71 8.9835666E7 -2500000.0 -0.22 -0.6556 -0.8844 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C16 mock treatment 8.171881E7 -1.53E7 -1.33 8.8234179E7 -4100000.0 -0.36 -1.1911 -0.8674 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C17 compound treatment 6.4207453E7 -3.29E7 -2.84 5.6568448E7 -3.58E7 -3.13 -4.2202 -0.9988 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C18 compound treatment 8.8294391E7 -8770000.0 -0.76 7.7817354E7 -1.45E7 -1.27 -1.4342 -0.9694 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C19 compound treatment 6.8092726E7 -2.9E7 -2.5 6.7831399E7 -2.45E7 -2.14 -3.286 -0.9971 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C20 compound treatment 7.2878658E7 -2.42E7 -2.09 6.8140204E7 -2.42E7 -2.12 -2.9745 -1.0 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C21 compound treatment 8.1854555E7 -1.52E7 -1.31 6.589781E7 -2.64E7 -2.31 -2.5651 -0.964 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C22 compound treatment 7.4538345E7 -2.25E7 -1.95 7.0611461E7 -2.17E7 -1.9 -2.7202 -0.9999 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C23 compound treatment 7.7278013E7 -1.98E7 -1.71 7.3036174E7 -1.93E7 -1.69 -2.4029 -1.0 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 C24 compound treatment 3.9270858E7 -5.78E7 -4.99 6.1515588E7 -3.08E7 -2.7 -5.4371 -0.9583 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D01 compound treatment 7.3633249E7 -2.34E7 -2.02 7.0841167E7 -2.15E7 -1.88 -2.7613 -0.9993 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D02 compound treatment 8.8878744E7 -8190000.0 -0.71 8.420091E7 -8140000.0 -0.71 -1.0034 -1.0 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D03 compound treatment 8.1851428E7 -1.52E7 -1.31 8.2088936E7 -1.02E7 -0.9 -1.5633 -0.9827 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D04 compound treatment 9.6178143E7 -886000.0 -0.08 9.1065231E7 -1270000.0 -0.11 -0.1328 -0.9833 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D05 compound treatment 7.1288711E7 -2.58E7 -2.23 7.0924245E7 -2.14E7 -1.87 -2.8994 -0.9963 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D06 compound treatment 9.1613737E7 -5450000.0 -0.47 8.6683554E7 -5650000.0 -0.49 -0.6828 -0.9997 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D07 compound treatment 8.8992748E7 -8070000.0 -0.7 8.7850253E7 -4490000.0 -0.39 -0.7706 -0.9631 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D08 compound treatment 8.9666911E7 -7400000.0 -0.64 8.8001368E7 -4340000.0 -0.38 -0.7201 -0.969 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D09 compound treatment 6.7553527E7 -2.95E7 -2.55 6.9268565E7 -2.31E7 -2.02 -3.2299 -0.9933 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D10 compound treatment 8.8812468E7 -8250000.0 -0.71 8.4856922E7 -7480000.0 -0.65 -0.9669 -0.9991 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D11 mock treatment 8.8732829E7 -8330000.0 -0.72 9.2563374E7 226000.0 0.02 -0.4949 -0.6874 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D12 mock treatment 8.2055475E7 -1.5E7 -1.3 8.7117557E7 -5220000.0 -0.46 -1.2397 -0.9019 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D13 compound treatment 7.9581355E7 -1.75E7 -1.51 8.2583119E7 -9750000.0 -0.85 -1.6714 -0.9635 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D14 compound treatment 6.5278408E7 -3.18E7 -2.75 6.4018582E7 -2.83E7 -2.48 -3.6938 -0.9987 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D15 mock treatment 9.0290825E7 -6770000.0 -0.59 9.2992459E7 655000.0 0.06 -0.3731 -0.6348 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D16 mock treatment 9.2279293E7 -4780000.0 -0.41 8.8955039E7 -3380000.0 -0.3 -0.5016 -0.9866 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D17 compound treatment 8.1270124E7 -1.58E7 -1.36 8.0457477E7 -1.19E7 -1.04 -1.6998 -0.991 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D18 compound treatment 9.3014956E7 -4050000.0 -0.35 9.2362739E7 25300.0 0.0 -0.2457 -0.7026 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D19 compound treatment 6.8604832E7 -2.85E7 -2.46 7.6866037E7 -1.55E7 -1.35 -2.6956 -0.9605 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D20 compound treatment 5.3448724E7 -4.36E7 -3.77 5.433915E7 -3.8E7 -3.33 -5.0153 -0.9981 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D21 compound treatment 8.2930651E7 -1.41E7 -1.22 8.2166147E7 -1.02E7 -0.89 -1.4926 -0.988 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D22 compound treatment 1.17556835E8 2.05E7 1.77 9.9380634E7 7040000.0 0.62 1.6874 0.9003 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D23 compound treatment 7.8756422E7 -1.83E7 -1.58 8.2808756E7 -9530000.0 -0.83 -1.7078 -0.9553 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 D24 compound treatment 1.1215051E8 1.51E7 1.3 1.02599979E8 1.03E7 0.9 1.5565 0.9835 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E01 mock treatment 1.02832214E8 5770000.0 0.5 1.02782221E8 1.04E7 0.91 0.9986 0.9593 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E02 mock treatment 1.03961985E8 6900000.0 0.6 9.4846946E7 2510000.0 0.22 0.5766 0.908 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E03 compound treatment 8.0394334E7 -1.67E7 -1.44 7.9450203E7 -1.29E7 -1.13 -1.8156 -0.9927 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E04 compound treatment 4.5522979E7 -5.15E7 -4.45 4.795954E7 -4.44E7 -3.88 -5.8941 -0.9977 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E05 compound treatment 7.1998912E7 -2.51E7 -2.16 7.4480209E7 -1.79E7 -1.56 -2.6359 -0.9872 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E06 compound treatment 7.7889559E7 -1.92E7 -1.66 7.5871402E7 -1.65E7 -1.44 -2.1901 -0.9976 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E07 compound treatment 3.2992262E7 -6.41E7 -5.53 3.7547129E7 -5.48E7 -4.8 -7.3038 -0.9975 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E08 compound treatment 2.0551394E7 -7.65E7 -6.61 2.0697294E7 -7.16E7 -6.27 -9.1064 -0.9997 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E09 mock treatment 8.982786E7 -7240000.0 -0.63 8.7794535E7 -4540000.0 -0.4 -0.7231 -0.9761 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E10 mock treatment 8.6550794E7 -1.05E7 -0.91 8.3026116E7 -9310000.0 -0.81 -1.2183 -0.9985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E11 compound treatment 8.0999983E7 -1.61E7 -1.39 8.1743993E7 -1.06E7 -0.93 -1.6367 -0.9808 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E12 compound treatment 7.4100244E7 -2.3E7 -1.98 7.5562406E7 -1.68E7 -1.47 -2.4406 -0.989 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E13 compound treatment 7.7793115E7 -1.93E7 -1.66 8.2457649E7 -9880000.0 -0.86 -1.7884 -0.9535 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E14 compound treatment 6.2441682E7 -3.46E7 -2.99 6.648246E7 -2.59E7 -2.26 -3.7146 -0.9905 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E15 compound treatment 3.985565E7 -5.72E7 -4.94 4.6543783E7 -4.58E7 -4.01 -6.3279 -0.9946 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E16 compound treatment 7.768045E7 -1.94E7 -1.67 7.9011229E7 -1.33E7 -1.17 -2.0085 -0.9844 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E17 mock treatment 1.01742105E8 4680000.0 0.4 9.6921248E7 4580000.0 0.4 0.5694 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E18 mock treatment 1.00410347E8 3350000.0 0.29 9.8013134E7 5680000.0 0.5 0.5556 0.9668 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E19 compound treatment 7.407257E7 -2.3E7 -1.99 8.3803975E7 -8530000.0 -0.75 -1.9323 -0.9108 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E20 compound treatment 9.3098648E7 -3970000.0 -0.34 8.9597696E7 -2740000.0 -0.24 -0.4117 -0.9848 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E21 compound treatment 7.3380088E7 -2.37E7 -2.05 7.2653843E7 -1.97E7 -1.72 -2.6646 -0.9963 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E22 compound treatment 2.239481E7 -7.47E7 -6.45 2.4393837E7 -6.79E7 -5.95 -8.765 -0.9992 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E23 compound treatment 9.191446E7 -5150000.0 -0.44 8.3168401E7 -9170000.0 -0.8 -0.8819 -0.9613 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 E24 compound treatment 4.7670002E7 -4.94E7 -4.27 7.1311855E7 -2.1E7 -1.84 -4.3179 -0.9293 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F01 mock treatment 1.04927442E8 7860000.0 0.68 9.9180433E7 6840000.0 0.6 0.9037 0.998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F02 mock treatment 1.02298189E8 5230000.0 0.45 9.792007E7 5580000.0 0.49 0.6651 0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F03 compound treatment 8.0777419E7 -1.63E7 -1.41 7.8467196E7 -1.39E7 -1.21 -1.8531 -0.9973 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F04 compound treatment 8.4992889E7 -1.21E7 -1.04 7.9773834E7 -1.26E7 -1.1 -1.5147 -0.9996 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F05 compound treatment 9.395192E7 -3110000.0 -0.27 9.1285103E7 -1050000.0 -0.09 -0.2552 -0.8981 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F06 compound treatment 6.7651092E7 -2.94E7 -2.54 6.0237115E7 -3.21E7 -2.81 -3.7829 -0.9987 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F07 compound treatment 8.0735427E7 -1.63E7 -1.41 7.5409995E7 -1.69E7 -1.48 -2.0448 -0.9997 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F08 compound treatment 8.8801551E7 -8260000.0 -0.71 8.643196E7 -5910000.0 -0.52 -0.8701 -0.9874 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F09 mock treatment 9.0206033E7 -6860000.0 -0.59 9.030383E7 -2030000.0 -0.18 -0.5447 -0.8807 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F10 mock treatment 8.7155167E7 -9910000.0 -0.86 8.611698E7 -6220000.0 -0.54 -0.9901 -0.9761 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F11 compound treatment 8.2315585E7 -1.47E7 -1.27 8.2914543E7 -9420000.0 -0.82 -1.4839 -0.9778 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F12 compound treatment 8.7717931E7 -9350000.0 -0.81 8.7225234E7 -5110000.0 -0.45 -0.8872 -0.9612 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F13 compound treatment 4.6042676E7 -5.1E7 -4.41 6.0625938E7 -3.17E7 -2.78 -5.0786 -0.9752 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F14 compound treatment 8.8489543E7 -8570000.0 -0.74 8.9245846E7 -3090000.0 -0.27 -0.715 -0.9068 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F15 compound treatment 8.920879E7 -7860000.0 -0.68 8.8582245E7 -3760000.0 -0.33 -0.7122 -0.9446 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F16 compound treatment 8.8391854E7 -8670000.0 -0.75 8.786265E7 -4470000.0 -0.39 -0.8066 -0.9542 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F17 mock treatment 1.03333545E8 6270000.0 0.54 9.8642265E7 6300000.0 0.55 0.7731 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F18 mock treatment 1.00452156E8 3390000.0 0.29 9.6427258E7 4090000.0 0.36 0.46 0.995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F19 compound treatment 7.6222435E7 -2.08E7 -1.8 7.5608879E7 -1.67E7 -1.46 -2.3081 -0.9947 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F20 compound treatment 9.6232839E7 -831000.0 -0.07 9.4363306E7 2030000.0 0.18 0.0746 0.39 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F21 compound treatment 8.4215391E7 -1.28E7 -1.11 8.6538681E7 -5800000.0 -0.51 -1.1436 -0.9371 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F22 compound treatment 8.6160908E7 -1.09E7 -0.94 8.0113839E7 -1.22E7 -1.07 -1.4224 -0.998 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F23 compound treatment 7.8996701E7 -1.81E7 -1.56 7.8217391E7 -1.41E7 -1.24 -1.9773 -0.9933 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 F24 compound treatment 1.08059836E8 1.1E7 0.95 9.9644746E7 7310000.0 0.64 1.1238 0.9815 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G01 compound treatment 8.9296389E7 -7770000.0 -0.67 8.4730542E7 -7610000.0 -0.67 -0.9452 -1.0 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G02 compound treatment 9.2108675E7 -4960000.0 -0.43 9.3443162E7 1110000.0 0.1 -0.2342 -0.5338 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G03 mock treatment 1.03531542E8 6470000.0 0.56 9.7364479E7 5030000.0 0.44 0.7061 0.993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G04 mock treatment 9.720318E7 139000.0 0.01 9.0893251E7 -1440000.0 -0.13 -0.0809 -0.6371 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G05 compound treatment 9.041515E7 -6650000.0 -0.57 8.121672E7 -1.11E7 -0.97 -1.0943 -0.9683 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G06 compound treatment 2.0263144E7 -7.68E7 -6.63 2.0743706E7 -7.16E7 -6.27 -9.1211 -0.9996 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G07 compound treatment 1.00719704E8 3660000.0 0.32 9.7114809E7 4780000.0 0.42 0.5189 0.9904 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G08 compound treatment 6.8122423E7 -2.89E7 -2.5 6.6837257E7 -2.55E7 -2.23 -3.3457 -0.9984 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G09 compound treatment 2.1460179E7 -7.56E7 -6.53 2.3502477E7 -6.88E7 -6.02 -8.8773 -0.9992 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G10 compound treatment 2.5693881E7 -7.14E7 -6.16 5.7235064E7 -3.51E7 -3.07 -6.5312 -0.9483 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G11 compound treatment 2.018031E7 -7.69E7 -6.64 2.0505007E7 -7.18E7 -6.29 -9.1409 -0.9996 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G12 compound treatment 7.9025069E7 -1.8E7 -1.56 7.8188737E7 -1.41E7 -1.24 -1.9773 -0.9935 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G13 compound treatment 8.4450468E7 -1.26E7 -1.09 8.1257064E7 -1.11E7 -0.97 -1.4561 -0.9983 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G14 compound treatment 3.6436839E7 -6.06E7 -5.24 3.7408853E7 -5.49E7 -4.81 -7.102 -0.9991 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G15 compound treatment 3.51194E7 -6.19E7 -5.35 3.0482536E7 -6.19E7 -5.41 -7.6111 -1.0 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G16 compound treatment 6.1845321E7 -3.52E7 -3.04 5.913731E7 -3.32E7 -2.91 -4.2055 -0.9997 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G17 compound treatment 2.0553611E7 -7.65E7 -6.61 2.1374181E7 -7.1E7 -6.21 -9.0644 -0.9995 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G18 compound treatment 9.4071592E7 -2990000.0 -0.26 8.9343953E7 -2990000.0 -0.26 -0.368 -1.0 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G19 mock treatment 9.9935283E7 2870000.0 0.25 9.6486701E7 4150000.0 0.36 0.4321 0.9827 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G20 mock treatment 9.995261E7 2890000.0 0.25 9.5967503E7 3630000.0 0.32 0.4011 0.9928 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G21 compound treatment 2.419291E7 -7.29E7 -6.29 2.5058621E7 -6.73E7 -5.89 -8.6141 -0.9994 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G22 compound treatment 4.9914039E7 -4.72E7 -4.07 4.1397577E7 -5.09E7 -4.46 -6.032 -0.999 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G23 compound treatment 8.4113379E7 -1.3E7 -1.12 8.0008184E7 -1.23E7 -1.08 -1.5539 -0.9998 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 G24 compound treatment 2.3981886E7 -7.31E7 -6.31 4.1898213E7 -5.04E7 -4.41 -7.5849 -0.9847 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H01 compound treatment 8.8280351E7 -8780000.0 -0.76 8.5617221E7 -6720000.0 -0.59 -0.9523 -0.9921 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H02 compound treatment 8.302022E7 -1.4E7 -1.21 9.5174361E7 2840000.0 0.25 -0.6822 -0.551 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H03 mock treatment 9.8666914E7 1600000.0 0.14 1.02768035E8 1.04E7 0.91 0.7434 0.8051 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H04 mock treatment 9.4220976E7 -2840000.0 -0.25 9.0287325E7 -2050000.0 -0.18 -0.3005 -0.9881 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H05 compound treatment 7.9666686E7 -1.74E7 -1.5 8.2647428E7 -9690000.0 -0.85 -1.6622 -0.9633 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H06 compound treatment 9.2305463E7 -4760000.0 -0.41 8.5125211E7 -7210000.0 -0.63 -0.737 -0.9784 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H07 compound treatment 7.6107072E7 -2.1E7 -1.81 7.4351846E7 -1.8E7 -1.57 -2.393 -0.9976 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H08 compound treatment 8.715142E7 -9910000.0 -0.86 8.8096517E7 -4240000.0 -0.37 -0.8679 -0.93 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H09 compound treatment 6.647795E7 -3.06E7 -2.64 6.7345952E7 -2.5E7 -2.19 -3.4146 -0.9956 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H10 compound treatment 7.4862079E7 -2.22E7 -1.92 7.1003197E7 -2.13E7 -1.87 -2.6762 -0.9999 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H11 compound treatment 6.273794E7 -3.43E7 -2.96 5.9483405E7 -3.29E7 -2.88 -4.1296 -0.9999 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H12 compound treatment 8.5182333E7 -1.19E7 -1.03 8.2710375E7 -9630000.0 -0.84 -1.3214 -0.9952 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H13 compound treatment 6.9678772E7 -2.74E7 -2.37 6.396065E7 -2.84E7 -2.48 -3.4286 -0.9997 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H14 compound treatment 4.26076E7 -5.45E7 -4.7 3.7635075E7 -5.47E7 -4.79 -6.7111 -1.0 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H15 compound treatment 9.2561574E7 -4500000.0 -0.39 8.7750999E7 -4590000.0 -0.4 -0.5588 -0.9999 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H16 compound treatment 9.2527517E7 -4540000.0 -0.39 8.7746422E7 -4590000.0 -0.4 -0.5612 -0.9999 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H17 compound treatment 7.2027551E7 -2.5E7 -2.16 7.4006596E7 -1.83E7 -1.6 -2.6635 -0.9892 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H18 compound treatment 5.1862552E7 -4.52E7 -3.9 3.787137E7 -5.45E7 -4.77 -6.1313 -0.9951 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H19 mock treatment 1.02868598E8 5800000.0 0.5 9.769675E7 5360000.0 0.47 0.6862 0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H20 mock treatment 9.7401522E7 337000.0 0.03 9.3187538E7 850000.0 0.07 0.0732 0.9163 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H21 compound treatment 8.012268E7 -1.69E7 -1.46 7.6678724E7 -1.57E7 -1.37 -2.0037 -0.9995 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H22 compound treatment 8.0714582E7 -1.63E7 -1.41 7.5178595E7 -1.72E7 -1.5 -2.0604 -0.9995 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H23 compound treatment 8.5762052E7 -1.13E7 -0.98 8.2515798E7 -9820000.0 -0.86 -1.2981 -0.998 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 H24 compound treatment 1.06152696E8 9090000.0 0.78 9.9347749E7 7010000.0 0.61 0.9889 0.9926 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I01 compound treatment 9.4462122E7 -2600000.0 -0.22 9.4482367E7 2140000.0 0.19 -0.0262 -0.0894 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I02 compound treatment 8.5962169E7 -1.11E7 -0.96 8.2332072E7 -1.0E7 -0.88 -1.2972 -0.999 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I03 compound treatment 1.04494579E8 7430000.0 0.64 9.7178059E7 4840000.0 0.42 0.7534 0.9797 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I04 compound treatment 4.1878984E7 -5.52E7 -4.77 4.1134818E7 -5.12E7 -4.48 -6.539 -0.9995 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I05 mock treatment 9.8081013E7 1020000.0 0.09 9.3950084E7 1610000.0 0.14 0.1619 0.974 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I06 mock treatment 9.7554944E7 491000.0 0.04 8.7886665E7 -4450000.0 -0.39 -0.2455 -0.6265 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I07 compound treatment 9.9240276E7 2180000.0 0.19 9.3140434E7 803000.0 0.07 0.1826 0.91 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I08 compound treatment 8.3272113E7 -1.38E7 -1.19 8.0285119E7 -1.21E7 -1.05 -1.5882 -0.9982 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I09 compound treatment 9.4650669E7 -2410000.0 -0.21 9.1300598E7 -1040000.0 -0.09 -0.2116 -0.9306 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I10 compound treatment 6.4653117E7 -3.24E7 -2.8 5.9343049E7 -3.3E7 -2.89 -4.0213 -0.9999 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I11 compound treatment 2.1596206E7 -7.55E7 -6.52 2.3083859E7 -6.93E7 -6.06 -8.8949 -0.9993 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I12 compound treatment 6.9320492E7 -2.77E7 -2.4 6.5603362E7 -2.67E7 -2.34 -3.3488 -0.9999 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I13 compound treatment 2.3108471E7 -7.4E7 -6.39 2.9303647E7 -6.3E7 -5.52 -8.4176 -0.9973 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I14 compound treatment 9.1789503E7 -5270000.0 -0.46 8.3843708E7 -8490000.0 -0.74 -0.8478 -0.9724 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I15 compound treatment 9.4799401E7 -2260000.0 -0.2 9.0496639E7 -1840000.0 -0.16 -0.2522 -0.9954 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I16 compound treatment 5.470451E7 -4.24E7 -3.66 6.0406763E7 -3.19E7 -2.79 -4.5631 -0.9912 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I17 compound treatment 9.1853051E7 -5210000.0 -0.45 8.7072657E7 -5260000.0 -0.46 -0.6441 -0.9999 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I18 compound treatment 7.7042398E7 -2.0E7 -1.73 7.7032088E7 -1.53E7 -1.34 -2.17 -0.992 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I19 compound treatment 7.2598352E7 -2.45E7 -2.11 7.176175E7 -2.06E7 -1.8 -2.7675 -0.9968 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I20 compound treatment 6.6183592E7 -3.09E7 -2.67 6.5949241E7 -2.64E7 -2.31 -3.519 -0.9974 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I21 mock treatment 1.01549484E8 4490000.0 0.39 9.5746279E7 3410000.0 0.3 0.4849 0.9917 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I22 mock treatment 1.01825527E8 4760000.0 0.41 9.8512998E7 6180000.0 0.54 0.673 0.9909 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I23 compound treatment 2.4311747E7 -7.28E7 -6.28 2.5309558E7 -6.7E7 -5.87 -8.5913 -0.9994 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 I24 compound treatment 2.1984469E7 -7.51E7 -6.48 2.2862946E7 -6.95E7 -6.08 -8.8848 -0.9995 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J01 compound treatment 9.0661925E7 -6400000.0 -0.55 8.8892113E7 -3450000.0 -0.3 -0.6042 -0.9593 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J02 compound treatment 1.07070355E8 1.0E7 0.86 9.5697893E7 3360000.0 0.29 0.8191 0.8972 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J03 compound treatment 8.1561684E7 -1.55E7 -1.34 7.9799616E7 -1.25E7 -1.1 -1.7227 -0.9951 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J04 compound treatment 9.5138723E7 -1930000.0 -0.17 9.1931905E7 -406000.0 -0.04 -0.1427 -0.8391 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J05 mock treatment 1.00139522E8 3080000.0 0.27 9.6018412E7 3680000.0 0.32 0.4156 0.9954 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J06 mock treatment 9.2224443E7 -4840000.0 -0.42 9.0429255E7 -1910000.0 -0.17 -0.4137 -0.919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J07 compound treatment 8.9082686E7 -7980000.0 -0.69 8.5037239E7 -7300000.0 -0.64 -0.9392 -0.9993 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J08 compound treatment 5.1898561E7 -4.52E7 -3.9 3.8900747E7 -5.34E7 -4.68 -6.0654 -0.9959 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J09 compound treatment 8.8987285E7 -8080000.0 -0.7 8.5402077E7 -6940000.0 -0.61 -0.9225 -0.9976 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J10 compound treatment 9.0735826E7 -6330000.0 -0.55 8.6628424E7 -5710000.0 -0.5 -0.7398 -0.999 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J11 compound treatment 8.1246554E7 -1.58E7 -1.37 7.8070125E7 -1.43E7 -1.25 -1.849 -0.999 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J12 compound treatment 6.3780019E7 -3.33E7 -2.87 5.1523418E7 -4.08E7 -3.57 -4.5586 -0.9942 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J13 compound treatment 8.5080705E7 -1.2E7 -1.04 7.9277836E7 -1.31E7 -1.14 -1.5401 -0.9988 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J14 compound treatment 9.3492843E7 -3570000.0 -0.31 8.1132247E7 -1.12E7 -0.98 -0.9115 -0.8867 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J15 compound treatment 5.7906738E7 -3.92E7 -3.38 5.9904497E7 -3.24E7 -2.84 -4.3986 -0.9962 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J16 compound treatment 9.2799099E7 -4270000.0 -0.37 8.9844304E7 -2490000.0 -0.22 -0.4148 -0.9687 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J17 compound treatment 7.9496178E7 -1.76E7 -1.52 7.6562264E7 -1.58E7 -1.38 -2.0492 -0.9989 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J18 compound treatment 8.1696546E7 -1.54E7 -1.33 7.3563944E7 -1.88E7 -1.64 -2.1004 -0.9944 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J19 compound treatment 9.1242195E7 -5820000.0 -0.5 8.6503634E7 -5830000.0 -0.51 -0.7166 -1.0 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J20 compound treatment 8.8612851E7 -8450000.0 -0.73 8.5520655E7 -6820000.0 -0.6 -0.938 -0.995 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J21 mock treatment 1.03784814E8 6720000.0 0.58 9.7588014E7 5250000.0 0.46 0.7354 0.9933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J22 mock treatment 1.00008948E8 2940000.0 0.25 9.6243991E7 3910000.0 0.34 0.4216 0.9894 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J23 compound treatment 8.2020246E7 -1.5E7 -1.3 7.4686176E7 -1.77E7 -1.54 -2.0111 -0.9963 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 J24 compound treatment 1.03262679E8 6200000.0 0.54 9.9496869E7 7160000.0 0.63 0.8216 0.9969 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K01 compound treatment 9.5057644E7 -2010000.0 -0.17 9.3514176E7 1180000.0 0.1 -0.0497 -0.2467 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K02 compound treatment 3.6107166E7 -6.1E7 -5.27 4.9203093E7 -4.31E7 -3.78 -6.3923 -0.9867 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K03 compound treatment 8.0383025E7 -1.67E7 -1.44 9.7132263E7 4790000.0 0.42 -0.7221 -0.4812 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K04 compound treatment 7.6705267E7 -2.04E7 -1.76 7.6229493E7 -1.61E7 -1.41 -2.2402 -0.994 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K05 compound treatment 1.02547504E8 5480000.0 0.47 1.02571484E8 1.02E7 0.9 0.9682 0.9556 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K06 compound treatment 2.0476649E7 -7.66E7 -6.62 2.0874934E7 -7.15E7 -6.25 -9.0999 -0.9996 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K07 mock treatment 9.9381409E7 2320000.0 0.2 9.5398934E7 3060000.0 0.27 0.331 0.9897 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K08 mock treatment 9.0227358E7 -6840000.0 -0.59 8.5188208E7 -7150000.0 -0.63 -0.86 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K09 compound treatment 8.1697189E7 -1.54E7 -1.33 8.0365737E7 -1.2E7 -1.05 -1.6794 -0.9931 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K10 compound treatment 8.2127682E7 -1.49E7 -1.29 8.1199602E7 -1.11E7 -0.97 -1.6015 -0.9904 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K11 compound treatment 2.4832001E7 -7.22E7 -6.24 2.7337755E7 -6.5E7 -5.69 -8.434 -0.9989 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K12 compound treatment 2.0084411E7 -7.7E7 -6.65 2.0826429E7 -7.15E7 -6.26 -9.1269 -0.9995 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K13 compound treatment 1.02479668E8 5420000.0 0.47 9.7013135E7 4680000.0 0.41 0.6201 0.9978 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K14 compound treatment 5.5390026E7 -4.17E7 -3.6 5.807384E7 -3.43E7 -3.0 -4.6656 -0.9959 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K15 mock treatment 9.8581816E7 1520000.0 0.13 8.6831274E7 -5510000.0 -0.48 -0.2481 -0.4967 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K16 mock treatment 9.2445045E7 -4620000.0 -0.4 8.8831694E7 -3510000.0 -0.31 -0.4991 -0.9916 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K17 compound treatment 2.2382964E7 -7.47E7 -6.45 2.3073769E7 -6.93E7 -6.06 -8.8474 -0.9995 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K18 compound treatment 5.519956E7 -4.19E7 -3.62 5.602588E7 -3.63E7 -3.18 -4.804 -0.9979 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K19 compound treatment 9.7711023E7 647000.0 0.06 9.6130795E7 3790000.0 0.33 0.2743 0.8147 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K20 compound treatment 6.5403855E7 -3.17E7 -2.73 6.6730366E7 -2.56E7 -2.24 -3.5183 -0.9951 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K21 compound treatment 8.8645836E7 -8420000.0 -0.73 8.6139451E7 -6200000.0 -0.54 -0.8977 -0.9896 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K22 compound treatment 4.4041459E7 -5.3E7 -4.58 4.4562544E7 -4.78E7 -4.18 -6.1948 -0.999 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K23 mock treatment 1.07947358E8 1.09E7 0.94 9.5595654E7 3260000.0 0.29 0.8663 0.8819 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 K24 mock treatment 9.9174827E7 2110000.0 0.18 1.03105252E8 1.08E7 0.94 0.7953 0.8285 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L01 compound treatment 7.7948121E7 -1.91E7 -1.65 8.152509E7 -1.08E7 -0.95 -1.8366 -0.9651 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L02 compound treatment 1.03997532E8 6930000.0 0.6 9.9504638E7 7170000.0 0.63 0.867 0.9997 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L03 compound treatment 7.6432597E7 -2.06E7 -1.78 8.0411514E7 -1.19E7 -1.04 -1.9981 -0.9675 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L04 compound treatment 8.7436304E7 -9630000.0 -0.83 9.4815372E7 2480000.0 0.22 -0.4347 -0.5058 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L05 compound treatment 9.159433E7 -5470000.0 -0.47 8.5835561E7 -6500000.0 -0.57 -0.7364 -0.9957 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L06 compound treatment 8.8087193E7 -8980000.0 -0.78 8.496178E7 -7380000.0 -0.65 -1.0047 -0.9958 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L07 mock treatment 1.02056983E8 4990000.0 0.43 9.6530882E7 4190000.0 0.37 0.5644 0.9968 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L08 mock treatment 9.1195645E7 -5870000.0 -0.51 8.8118763E7 -4220000.0 -0.37 -0.6195 -0.9879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L09 compound treatment 7.319848E7 -2.39E7 -2.06 7.0435585E7 -2.19E7 -1.92 -2.813 -0.9993 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L10 compound treatment 8.9375304E7 -7690000.0 -0.66 8.8577898E7 -3760000.0 -0.33 -0.7022 -0.9475 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L11 compound treatment 8.957493E7 -7490000.0 -0.65 8.0901346E7 -1.14E7 -1.0 -1.1651 -0.9777 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L12 compound treatment 9.0036682E7 -7030000.0 -0.61 9.010964E7 -2230000.0 -0.19 -0.5671 -0.8895 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L13 compound treatment 9.1276164E7 -5790000.0 -0.5 8.7879877E7 -4460000.0 -0.39 -0.6294 -0.9925 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L14 compound treatment 9.2729367E7 -4330000.0 -0.37 8.5125998E7 -7210000.0 -0.63 -0.711 -0.9689 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L15 mock treatment 9.6472801E7 -591000.0 -0.05 8.736786E7 -4970000.0 -0.43 -0.3437 -0.7848 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L16 mock treatment 9.5896347E7 -1170000.0 -0.1 8.1701917E7 -1.06E7 -0.93 -0.7295 -0.7792 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L17 compound treatment 8.6066773E7 -1.1E7 -0.95 8.2043867E7 -1.03E7 -0.9 -1.3087 -0.9996 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L18 compound treatment 9.7823015E7 759000.0 0.07 8.9105334E7 -3230000.0 -0.28 -0.1537 -0.5292 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L19 compound treatment 4.7642471E7 -4.94E7 -4.27 4.3539544E7 -4.88E7 -4.27 -6.0382 -1.0 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L20 compound treatment 1.0053612E8 3470000.0 0.3 9.7732457E7 5400000.0 0.47 0.5459 0.976 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L21 compound treatment 9.5012073E7 -2050000.0 -0.18 9.3630613E7 1290000.0 0.11 -0.0453 -0.2154 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L22 compound treatment 1.01785784E8 4720000.0 0.41 9.6771855E7 4430000.0 0.39 0.5628 0.9997 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L23 mock treatment 1.09060783E8 1.2E7 1.04 1.05630333E8 1.33E7 1.16 1.5553 0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 L24 mock treatment 1.07875229E8 1.08E7 0.93 1.0334808E8 1.1E7 0.96 1.3417 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M01 compound treatment 6.5564174E7 -3.15E7 -2.72 4.0897259E7 -5.14E7 -4.5 -5.1072 -0.9709 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M02 compound treatment 2.0566097E7 -7.65E7 -6.61 2.2310337E7 -7.0E7 -6.13 -9.0057 -0.9993 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M03 compound treatment 3.4752208E7 -6.23E7 -5.38 5.6780199E7 -3.56E7 -3.11 -6.0061 -0.9661 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M04 compound treatment 5.8290635E7 -3.88E7 -3.35 5.6798433E7 -3.55E7 -3.11 -4.5674 -0.9993 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M05 compound treatment 2.6794017E7 -7.03E7 -6.07 3.5190457E7 -5.71E7 -5.0 -7.8282 -0.9954 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M06 compound treatment 2.0833592E7 -7.62E7 -6.58 2.0964384E7 -7.14E7 -6.25 -9.0726 -0.9997 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M07 compound treatment 2.2923439E7 -7.41E7 -6.4 2.4236122E7 -6.81E7 -5.96 -8.7425 -0.9994 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M08 compound treatment 2.9606786E7 -6.75E7 -5.83 4.1679474E7 -5.07E7 -4.43 -7.2549 -0.9909 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M09 mock treatment 9.9859074E7 2790000.0 0.24 8.9585593E7 -2750000.0 -0.24 4.0E-4 0.0012 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M10 mock treatment 8.9143225E7 -7920000.0 -0.68 8.6290683E7 -6050000.0 -0.53 -0.858 -0.9919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M11 compound treatment 8.6815984E7 -1.02E7 -0.89 8.287627E7 -9460000.0 -0.83 -1.2114 -0.9994 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M12 compound treatment 7.3634866E7 -2.34E7 -2.02 6.4221713E7 -2.81E7 -2.46 -3.1709 -0.9953 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M13 mock treatment 9.2747195E7 -4320000.0 -0.37 9.4087788E7 1750000.0 0.15 -0.1553 -0.3854 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M14 mock treatment 9.982741E7 2760000.0 0.24 8.7715784E7 -4620000.0 -0.4 -0.1172 -0.2496 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M15 compound treatment 7.8973812E7 -1.81E7 -1.56 7.1119502E7 -2.12E7 -1.86 -2.4179 -0.9963 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M16 compound treatment 7.0917408E7 -2.61E7 -2.26 6.6825753E7 -2.55E7 -2.23 -3.1757 -1.0 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M17 compound treatment 6.4351548E7 -3.27E7 -2.83 6.4145898E7 -2.82E7 -2.47 -3.7425 -0.9977 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M18 compound treatment 9.3300276E7 -3760000.0 -0.33 8.2283757E7 -1.01E7 -0.88 -0.852 -0.9084 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M19 compound treatment 7.5638651E7 -2.14E7 -1.85 8.1742248E7 -1.06E7 -0.93 -1.9642 -0.949 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M20 compound treatment 2.6601774E7 -7.05E7 -6.09 4.4816484E7 -4.75E7 -4.16 -7.2443 -0.9828 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M21 compound treatment 6.3319652E7 -3.37E7 -2.91 5.5856292E7 -3.65E7 -3.19 -4.3185 -0.999 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M22 compound treatment 6.6721352E7 -3.03E7 -2.62 7.5262833E7 -1.71E7 -1.49 -2.9098 -0.9645 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M23 compound treatment 7.562201E7 -2.14E7 -1.85 7.5784078E7 -1.66E7 -1.45 -2.334 -0.9926 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 M24 compound treatment 2.1045922E7 -7.6E7 -6.57 2.1037889E7 -7.13E7 -6.24 -9.0551 -0.9997 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N01 compound treatment 8.3320371E7 -1.37E7 -1.19 8.0014616E7 -1.23E7 -1.08 -1.602 -0.9989 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N02 compound treatment 8.7051053E7 -1.0E7 -0.86 1.01797178E8 9460000.0 0.83 -0.0261 -0.0218 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N03 compound treatment 9.7249434E7 185000.0 0.02 8.909722E7 -3240000.0 -0.28 -0.1892 -0.6661 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N04 compound treatment 1.00798102E8 3730000.0 0.32 9.1375389E7 -962000.0 -0.08 0.1685 0.5056 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N05 compound treatment 9.6080167E7 -984000.0 -0.08 9.2557501E7 220000.0 0.02 -0.0465 -0.5334 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N06 compound treatment 9.6197721E7 -866000.0 -0.07 9.4614355E7 2280000.0 0.2 0.088 0.4134 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N07 compound treatment 8.3531671E7 -1.35E7 -1.17 7.5437386E7 -1.69E7 -1.48 -1.8723 -0.9932 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N08 compound treatment 8.6908904E7 -1.02E7 -0.88 8.7896478E7 -4440000.0 -0.39 -0.8951 -0.9329 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N09 mock treatment 1.0135328E8 4290000.0 0.37 9.07795E7 -1560000.0 -0.14 0.1655 0.4194 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N10 mock treatment 9.6994536E7 -69600.0 -0.01 8.2573197E7 -9760000.0 -0.85 -0.6085 -0.7121 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N11 compound treatment 7.0497495E7 -2.66E7 -2.29 6.9241525E7 -2.31E7 -2.02 -3.0518 -0.998 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N12 compound treatment 7.1403598E7 -2.57E7 -2.22 8.8943412E7 -3390000.0 -0.3 -1.7772 -0.7948 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N13 mock treatment 1.03378572E8 6310000.0 0.55 8.5952912E7 -6380000.0 -0.56 -0.0095 -0.0121 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N14 mock treatment 9.7825266E7 761000.0 0.07 9.1418179E7 -919000.0 -0.08 -0.0104 -0.1001 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N15 compound treatment 7.5321909E7 -2.17E7 -1.88 6.9158872E7 -2.32E7 -2.03 -2.7623 -0.9993 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N16 compound treatment 9.8659727E7 1600000.0 0.14 8.2678258E7 -9660000.0 -0.85 -0.5003 -0.5841 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N17 compound treatment 8.0876139E7 -1.62E7 -1.4 6.5723413E7 -2.66E7 -2.33 -2.6357 -0.9702 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N18 compound treatment 1.01262167E8 4200000.0 0.36 8.4903552E7 -7430000.0 -0.65 -0.2036 -0.2734 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N19 compound treatment 9.1515227E7 -5550000.0 -0.48 8.6898184E7 -5440000.0 -0.48 -0.6755 -1.0 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N20 compound treatment 1.01650839E8 4590000.0 0.4 9.6048588E7 3710000.0 0.32 0.5098 0.9951 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N21 compound treatment 5.1736531E7 -4.53E7 -3.92 5.2288849E7 -4.0E7 -3.5 -5.2467 -0.9985 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N22 compound treatment 8.2469003E7 -1.46E7 -1.26 6.9286244E7 -2.31E7 -2.02 -2.3179 -0.9744 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N23 compound treatment 8.3435685E7 -1.36E7 -1.18 8.1937118E7 -1.04E7 -0.91 -1.476 -0.9919 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 N24 compound treatment 9.9199725E7 2140000.0 0.18 1.01537346E8 9200000.0 0.81 0.6998 0.8472 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O01 compound treatment 1.14182521E8 1.71E7 1.48 1.00538939E8 8200000.0 0.72 1.553 0.9449 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O02 compound treatment 6.7225862E7 -2.98E7 -2.58 6.7410382E7 -2.49E7 -2.18 -3.365 -0.9966 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O03 compound treatment 8.4566586E7 -1.25E7 -1.08 8.5775413E7 -6560000.0 -0.57 -1.1694 -0.9564 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O04 compound treatment 2.0793361E7 -7.63E7 -6.59 2.090316E7 -7.14E7 -6.25 -9.0789 -0.9997 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O05 compound treatment 3.2390137E7 -6.47E7 -5.59 3.360145E7 -5.87E7 -5.14 -7.5848 -0.9991 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O06 compound treatment 2.5918811E7 -7.11E7 -6.14 2.6377278E7 -6.6E7 -5.77 -8.4271 -0.9995 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O07 compound treatment 7.2572985E7 -2.45E7 -2.12 7.0661052E7 -2.17E7 -1.9 -2.8372 -0.9985 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O08 compound treatment 8.6529585E7 -1.05E7 -0.91 7.7891334E7 -1.44E7 -1.26 -1.5374 -0.987 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O09 compound treatment 7.3009267E7 -2.41E7 -2.08 6.8135853E7 -2.42E7 -2.12 -2.9668 -1.0 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O10 compound treatment 7.4863502E7 -2.22E7 -1.92 7.1375355E7 -2.1E7 -1.83 -2.6531 -0.9998 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O11 mock treatment 9.9920463E7 2860000.0 0.25 9.2384754E7 47300.0 0.0 0.1774 0.7189 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O12 mock treatment 9.4699497E7 -2360000.0 -0.2 8.864097E7 -3700000.0 -0.32 -0.3732 -0.9754 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O13 compound treatment 9.0620939E7 -6440000.0 -0.56 7.986962E7 -1.25E7 -1.09 -1.1651 -0.9512 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O14 compound treatment 7.8895262E7 -1.82E7 -1.57 7.5466162E7 -1.69E7 -1.48 -2.1537 -0.9995 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O15 compound treatment 2.1595699E7 -7.55E7 -6.52 2.2394909E7 -6.99E7 -6.12 -8.9375 -0.9995 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O16 compound treatment 6.5111743E7 -3.2E7 -2.76 6.484624E7 -2.75E7 -2.41 -3.6528 -0.9977 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O17 compound treatment 7.2831846E7 -2.42E7 -2.09 7.1361629E7 -2.1E7 -1.84 -2.778 -0.9979 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O18 compound treatment 7.4675681E7 -2.24E7 -1.93 7.1417855E7 -2.09E7 -1.83 -2.662 -0.9996 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O19 compound treatment 4.4391185E7 -5.27E7 -4.55 4.7033708E7 -4.53E7 -3.96 -6.0206 -0.9977 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O20 compound treatment 9.3127276E7 -3940000.0 -0.34 8.4112262E7 -8230000.0 -0.72 -0.7495 -0.9414 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O21 compound treatment 6.4596172E7 -3.25E7 -2.8 6.873062E7 -2.36E7 -2.07 -3.4439 -0.9887 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O22 compound treatment 2.4134343E7 -7.29E7 -6.3 2.4947498E7 -6.74E7 -5.9 -8.6245 -0.9995 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O23 compound treatment 2.0891107E7 -7.62E7 -6.58 2.1074031E7 -7.13E7 -6.24 -9.0623 -0.9996 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 O24 compound treatment 5.618062E7 -4.09E7 -3.53 5.8239715E7 -3.41E7 -2.98 -4.6071 -0.9965 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P01 compound treatment 6.3651865E7 -3.34E7 -2.89 6.2420176E7 -2.99E7 -2.62 -3.892 -0.9988 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P02 compound treatment 1.03076967E8 6010000.0 0.52 1.00665847E8 8330000.0 0.73 0.8826 0.9862 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P03 compound treatment 7.4169305E7 -2.29E7 -1.98 8.5255847E7 -7080000.0 -0.62 -1.8365 -0.8862 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P04 compound treatment 9.5644197E7 -1420000.0 -0.12 8.2275092E7 -1.01E7 -0.88 -0.7094 -0.7979 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P05 compound treatment 2.0718558E7 -7.63E7 -6.59 2.0658082E7 -7.17E7 -6.27 -9.0986 -0.9997 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P06 compound treatment 1.01356773E8 4290000.0 0.37 9.2720971E7 384000.0 0.03 0.2859 0.768 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P07 compound treatment 8.9755283E7 -7310000.0 -0.63 8.5817143E7 -6520000.0 -0.57 -0.8499 -0.9987 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P08 compound treatment 1.00465359E8 3400000.0 0.29 9.1574907E7 -763000.0 -0.07 0.1605 0.5329 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P09 compound treatment 7.6920171E7 -2.01E7 -1.74 7.4200707E7 -1.81E7 -1.59 -2.3527 -0.9989 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P10 compound treatment 9.4748945E7 -2320000.0 -0.2 8.5780216E7 -6560000.0 -0.57 -0.5472 -0.9004 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P11 mock treatment 9.956271E7 2500000.0 0.22 9.6791755E7 4450000.0 0.39 0.4282 0.9611 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P12 mock treatment 9.528091E7 -1780000.0 -0.15 9.017427E7 -2160000.0 -0.19 -0.2428 -0.9948 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P13 compound treatment 7.4302749E7 -2.28E7 -1.97 6.3301514E7 -2.9E7 -2.54 -3.187 -0.992 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P14 compound treatment 9.4497947E7 -2570000.0 -0.22 7.6823648E7 -1.55E7 -1.36 -1.1168 -0.8118 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P15 compound treatment 7.5815243E7 -2.12E7 -1.84 7.6091063E7 -1.62E7 -1.42 -2.3032 -0.992 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P16 compound treatment 9.4830665E7 -2230000.0 -0.19 9.0001528E7 -2340000.0 -0.2 -0.281 -0.9996 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P17 compound treatment 7.9067472E7 -1.8E7 -1.55 7.7544553E7 -1.48E7 -1.29 -2.0146 -0.9959 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P18 compound treatment 9.754886E7 485000.0 0.04 9.273959E7 402000.0 0.04 0.0545 0.9963 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P19 compound treatment 8.7924005E7 -9140000.0 -0.79 8.5421202E7 -6920000.0 -0.61 -0.9862 -0.9914 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P20 compound treatment 9.5881307E7 -1180000.0 -0.1 9.1771036E7 -566000.0 -0.05 -0.1073 -0.9448 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P21 compound treatment 8.2661519E7 -1.44E7 -1.24 8.4070021E7 -8270000.0 -0.72 -1.3913 -0.9668 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P22 compound treatment 1.02818408E8 5750000.0 0.5 1.00532925E8 8200000.0 0.72 0.8586 0.9839 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P23 compound treatment 2.5723954E7 -7.13E7 -6.16 2.773766E7 -6.46E7 -5.65 -8.3548 -0.9991 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2102 P24 compound treatment 1.08082049E8 1.1E7 0.95 1.04283991E8 1.19E7 1.05 1.4122 0.9989 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A01 compound treatment 9.7181102E7 676000.0 0.06 8.7435077E7 -8160000.0 -0.71 -0.4638 -0.6471 3070297 PK04_103001 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A02 compound treatment 1.02156016E8 5650000.0 0.49 9.9464844E7 3870000.0 0.34 0.5845 0.984 3189402 PK04_103002 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A03 compound treatment 9.7735255E7 1230000.0 0.11 9.7476724E7 1880000.0 0.16 0.1915 0.9776 3070298 PK04_103003 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A04 compound treatment 9.4522391E7 -1980000.0 -0.17 9.491302E7 -683000.0 -0.06 -0.1634 -0.9007 3189403 PK04_103004 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A05 compound treatment 9.928889E7 2780000.0 0.24 8.8541234E7 -7060000.0 -0.62 -0.2666 -0.4023 3070299 PK04_103005 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A06 compound treatment 9.8312188E7 1810000.0 0.16 9.2247783E7 -3350000.0 -0.29 -0.0968 -0.2917 3189404 PK04_103006 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A07 compound treatment 8.5854219E7 -1.07E7 -0.92 9.6375135E7 779000.0 0.07 -0.6023 -0.6529 3070300 PK04_103007 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A08 compound treatment 9.6783219E7 278000.0 0.02 9.103219E7 -4560000.0 -0.4 -0.2655 -0.6634 3189405 PK04_103008 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A09 compound treatment 9.4342658E7 -2160000.0 -0.19 8.5640706E7 -9960000.0 -0.87 -0.7482 -0.8396 3189406 PK04_103009 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A10 compound treatment 9.1530573E7 -4970000.0 -0.43 8.6111653E7 -9480000.0 -0.83 -0.8908 -0.953 3070355 PK04_103010 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A11 compound treatment 8.7237127E7 -9270000.0 -0.8 9.0937624E7 -4660000.0 -0.41 -0.8543 -0.951 3189407 PK04_103011 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A12 compound treatment 8.8650756E7 -7850000.0 -0.68 8.4992778E7 -1.06E7 -0.93 -1.1359 -0.9881 3189408 PK04_103012 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A13 mock treatment 9.4149479E7 -2360000.0 -0.2 7.8144186E7 -1.75E7 -1.53 -1.2239 -0.7943 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A14 mock treatment 9.6005591E7 -499000.0 -0.04 9.0312694E7 -5280000.0 -0.46 -0.3575 -0.7697 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A15 compound treatment 7.4885598E7 -2.16E7 -1.87 8.1443659E7 -1.42E7 -1.24 -2.1962 -0.9801 3070356 PK04_103013 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A16 compound treatment 9.5016623E7 -1490000.0 -0.13 8.2995063E7 -1.26E7 -1.1 -0.8707 -0.7842 3189409 PK04_103014 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A17 compound treatment 9.1963931E7 -4540000.0 -0.39 8.3862094E7 -1.17E7 -1.03 -1.0035 -0.9129 3070357 PK04_103015 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A18 compound treatment 9.7814388E7 1310000.0 0.11 9.7225953E7 1630000.0 0.14 0.1808 0.9934 3189410 PK04_103016 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A19 compound treatment 7.812153E7 -1.84E7 -1.59 8.0964965E7 -1.46E7 -1.28 -2.0282 -0.9943 3070358 PK04_103017 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A20 compound treatment 1.01284499E8 4780000.0 0.41 9.2842447E7 -2750000.0 -0.24 0.1215 0.2541 3189411 PK04_103018 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A21 compound treatment 1.01593983E8 5090000.0 0.44 1.06442558E8 1.08E7 0.95 0.982 0.9388 3070359 PK04_103019 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A22 compound treatment 1.02462969E8 5960000.0 0.51 1.04432252E8 8840000.0 0.77 0.9107 0.9804 3189412 PK04_103020 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A23 compound treatment 9.7521016E7 1020000.0 0.09 9.5426939E7 -169000.0 -0.01 0.0516 0.5795 3070360 PK04_103021 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 A24 compound treatment 1.04769799E8 8260000.0 0.71 1.03195528E8 7600000.0 0.67 0.975 0.9994 3189413 PK04_103022 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B01 compound treatment 1.02202283E8 5700000.0 0.49 1.02054664E8 6460000.0 0.57 0.7476 0.9976 3189525 PK04_103023 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B02 compound treatment 8.0964631E7 -1.55E7 -1.34 7.7646831E7 -1.79E7 -1.57 -2.0599 -0.9969 3070361 PK04_103024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B03 compound treatment 9.1212622E7 -5290000.0 -0.46 9.0197961E7 -5400000.0 -0.47 -0.6573 -0.9999 3189526 PK04_103025 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B04 compound treatment 9.8662095E7 2160000.0 0.19 9.6815961E7 1220000.0 0.11 0.2072 0.9651 3189527 PK04_103026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B05 compound treatment 9.4689806E7 -1820000.0 -0.16 9.0580595E7 -5020000.0 -0.44 -0.4213 -0.9038 3070362 PK04_103027 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B06 compound treatment 7.3804762E7 -2.27E7 -1.96 7.0021335E7 -2.56E7 -2.24 -2.9691 -0.9978 3189528 PK04_103028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B07 compound treatment 8.9650227E7 -6850000.0 -0.59 9.0536579E7 -5060000.0 -0.44 -0.7318 -0.9898 3070363 PK04_103029 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B08 compound treatment 9.2325467E7 -4180000.0 -0.36 9.1886024E7 -3710000.0 -0.32 -0.4849 -0.9986 3189529 PK04_103030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B09 compound treatment 9.0691842E7 -5810000.0 -0.5 9.1408546E7 -4190000.0 -0.37 -0.6142 -0.988 3189530 PK04_103031 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B10 compound treatment 8.4175925E7 -1.23E7 -1.06 7.8971912E7 -1.66E7 -1.45 -1.7818 -0.9882 3070364 PK04_103032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B11 compound treatment 9.0235593E7 -6270000.0 -0.54 9.2070406E7 -3530000.0 -0.31 -0.6011 -0.9644 3189531 PK04_103033 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B12 compound treatment 8.8930515E7 -7570000.0 -0.65 8.7214103E7 -8380000.0 -0.73 -0.9813 -0.9984 3189532 PK04_103034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B13 mock treatment 9.2927372E7 -3580000.0 -0.31 9.2108508E7 -3490000.0 -0.31 -0.4343 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B14 mock treatment 8.2220524E7 -1.43E7 -1.23 8.0793981E7 -1.48E7 -1.3 -1.7884 -0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B15 compound treatment 8.7302554E7 -9200000.0 -0.79 8.8931323E7 -6660000.0 -0.58 -0.9745 -0.9884 3070365 PK04_103035 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B16 compound treatment 9.0906842E7 -5600000.0 -0.48 9.0112235E7 -5480000.0 -0.48 -0.6813 -1.0 3189533 PK04_103036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B17 compound treatment 9.4865E7 -1640000.0 -0.14 9.2517924E7 -3080000.0 -0.27 -0.2907 -0.9549 3070366 PK04_103037 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B18 compound treatment 8.6413524E7 -1.01E7 -0.87 8.7776515E7 -7820000.0 -0.68 -1.1003 -0.9928 3189534 PK04_103038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B19 compound treatment 9.6669995E7 165000.0 0.01 9.6820399E7 1220000.0 0.11 0.0858 0.7941 3189535 PK04_103039 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B20 compound treatment 9.3033801E7 -3470000.0 -0.3 9.508039E7 -516000.0 -0.05 -0.2439 -0.8045 3070367 PK04_103040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B21 compound treatment 1.02614627E8 6110000.0 0.53 1.04349605E8 8750000.0 0.77 0.9148 0.9834 3189536 PK04_103041 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B22 compound treatment 9.30327E7 -3470000.0 -0.3 9.1810487E7 -3790000.0 -0.33 -0.4464 -0.9988 3189537 PK04_103042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B23 compound treatment 1.02400429E8 5900000.0 0.51 1.02762047E8 7170000.0 0.63 0.8035 0.9947 3070368 PK04_103043 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 B24 compound treatment 9.9171743E7 2670000.0 0.23 9.9159852E7 3560000.0 0.31 0.3834 0.9889 3189538 PK04_103044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C01 compound treatment 9.6024649E7 -480000.0 -0.04 1.01301347E8 5710000.0 0.5 0.3237 0.6461 3070369 PK04_103045 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C02 compound treatment 9.3656954E7 -2850000.0 -0.25 8.2728964E7 -1.29E7 -1.13 -0.9702 -0.8417 3189539 PK04_103046 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C03 compound treatment 9.2244918E7 -4260000.0 -0.37 9.2867416E7 -2730000.0 -0.24 -0.4291 -0.9781 3189540 PK04_103047 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C04 compound treatment 8.3430844E7 -1.31E7 -1.13 8.5598358E7 -1.0E7 -0.87 -1.4172 -0.992 3070370 PK04_103048 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C05 compound treatment 9.5152407E7 -1350000.0 -0.12 9.3383796E7 -2210000.0 -0.19 -0.2195 -0.9707 3189541 PK04_103049 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C06 compound treatment 1.00369566E8 3860000.0 0.33 8.392079E7 -1.17E7 -1.02 -0.4865 -0.4526 3189542 PK04_103050 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C07 compound treatment 9.2242675E7 -4260000.0 -0.37 9.5147478E7 -449000.0 -0.04 -0.2881 -0.7781 3070371 PK04_103051 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C08 compound treatment 9.0054522E7 -6450000.0 -0.56 8.9078979E7 -6520000.0 -0.57 -0.7973 -0.9999 3189543 PK04_103052 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C09 compound treatment 8.9915213E7 -6590000.0 -0.57 8.8826626E7 -6770000.0 -0.59 -0.8214 -0.9998 3070372 PK04_103053 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C10 compound treatment 8.042478E7 -1.61E7 -1.39 7.7017996E7 -1.86E7 -1.63 -2.1318 -0.9969 3189544 PK04_103054 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C11 mock treatment 9.0737611E7 -5770000.0 -0.5 8.9026671E7 -6570000.0 -0.57 -0.7588 -0.9974 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C12 mock treatment 8.8745905E7 -7760000.0 -0.67 8.7243073E7 -8350000.0 -0.73 -0.9908 -0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C13 compound treatment 8.8063618E7 -8440000.0 -0.73 9.2785949E7 -2810000.0 -0.25 -0.6895 -0.896 3189545 PK04_103055 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C14 compound treatment 7.9462322E7 -1.7E7 -1.47 7.7542742E7 -1.81E7 -1.58 -2.1581 -0.9994 3189546 PK04_103056 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C15 mock treatment 9.3744687E7 -2760000.0 -0.24 9.3871035E7 -1730000.0 -0.15 -0.2754 -0.9757 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C16 mock treatment 9.210212E7 -4400000.0 -0.38 8.9925911E7 -5670000.0 -0.5 -0.6198 -0.9914 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C17 compound treatment 8.9345883E7 -7160000.0 -0.62 8.9657602E7 -5940000.0 -0.52 -0.8048 -0.9963 3070427 PK04_103057 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C18 compound treatment 9.3487115E7 -3020000.0 -0.26 9.061004E7 -4990000.0 -0.44 -0.4929 -0.9697 3189660 PK04_103058 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C19 compound treatment 8.8631645E7 -7870000.0 -0.68 8.7600949E7 -8000000.0 -0.7 -0.9756 -0.9999 3070428 PK04_103059 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C20 compound treatment 9.9938879E7 3430000.0 0.3 1.00781674E8 5190000.0 0.45 0.5306 0.9787 3189661 PK04_103060 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C21 compound treatment 9.5979288E7 -526000.0 -0.05 9.9037324E7 3440000.0 0.3 0.1808 0.5938 3189662 PK04_103061 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C22 compound treatment 1.04595151E8 8090000.0 0.7 9.6404744E7 808000.0 0.07 0.5441 0.7747 3070429 PK04_103062 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C23 compound treatment 9.8351897E7 1850000.0 0.16 1.05608479E8 1.0E7 0.88 0.7324 0.8223 3189663 PK04_103063 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 C24 compound treatment 1.11229177E8 1.47E7 1.27 1.10158221E8 1.46E7 1.27 1.8004 1.0 3189664 PK04_103064 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D01 compound treatment 9.2581867E7 -3920000.0 -0.34 8.841182E7 -7180000.0 -0.63 -0.6842 -0.9579 3070430 PK04_103065 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D02 compound treatment 3.0606486E7 -6.59E7 -5.69 2.2803309E7 -7.28E7 -6.37 -8.5295 -0.9984 3189665 PK04_103066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D03 compound treatment 9.8437718E7 1930000.0 0.17 9.9406141E7 3810000.0 0.33 0.3538 0.9488 3070431 PK04_103067 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D04 compound treatment 9.9227892E7 2720000.0 0.24 8.7055767E7 -8540000.0 -0.75 -0.3622 -0.4623 3189666 PK04_103068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D05 compound treatment 9.4044493E7 -2460000.0 -0.21 9.2064637E7 -3530000.0 -0.31 -0.3688 -0.9833 3189667 PK04_103069 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D06 compound treatment 7.2390017E7 -2.41E7 -2.08 7.8371105E7 -1.72E7 -1.51 -2.5388 -0.9874 3189668 PK04_103070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D07 compound treatment 9.0772114E7 -5730000.0 -0.5 9.1722172E7 -3870000.0 -0.34 -0.5899 -0.9829 3070432 PK04_103071 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D08 compound treatment 9.312826E7 -3380000.0 -0.29 8.2689579E7 -1.29E7 -1.13 -1.005 -0.8614 3189669 PK04_103072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D09 compound treatment 9.0817852E7 -5690000.0 -0.49 8.7715225E7 -7880000.0 -0.69 -0.8351 -0.9862 3070433 PK04_103073 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D10 compound treatment 8.1400144E7 -1.51E7 -1.3 8.9733414E7 -5860000.0 -0.51 -1.2853 -0.9168 3189670 PK04_103074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D11 mock treatment 9.1037769E7 -5470000.0 -0.47 9.4563854E7 -1030000.0 -0.09 -0.3978 -0.8274 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D12 mock treatment 8.4477209E7 -1.2E7 -1.04 8.2435324E7 -1.32E7 -1.15 -1.549 -0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D13 compound treatment 8.2654066E7 -1.39E7 -1.2 9.1607628E7 -3990000.0 -0.35 -1.0928 -0.8769 3189671 PK04_103075 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D14 compound treatment 7.8438817E7 -1.81E7 -1.56 9.2618124E7 -2980000.0 -0.26 -1.2877 -0.8139 3070434 PK04_103076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D15 mock treatment 9.4139534E7 -2370000.0 -0.2 9.541161E7 -185000.0 -0.02 -0.1559 -0.7607 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D16 mock treatment 9.2621667E7 -3880000.0 -0.34 8.4425751E7 -1.12E7 -0.98 -0.9285 -0.8983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D17 compound treatment 8.9679636E7 -6830000.0 -0.59 8.9292781E7 -6300000.0 -0.55 -0.8069 -0.9995 3189672 PK04_103077 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D18 compound treatment 8.7343769E7 -9160000.0 -0.79 9.4344783E7 -1250000.0 -0.11 -0.637 -0.7974 3189673 PK04_103078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D19 compound treatment 9.4869433E7 -1640000.0 -0.14 9.7662219E7 2070000.0 0.18 0.028 0.1218 3070435 PK04_103079 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D20 compound treatment 9.7731458E7 1230000.0 0.11 9.2350009E7 -3250000.0 -0.28 -0.126 -0.4155 3189674 PK04_103080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D21 compound treatment 1.03544957E8 7040000.0 0.61 1.01905391E8 6310000.0 0.55 0.8204 0.9988 3189675 PK04_103081 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D22 compound treatment 8.5183006E7 -1.13E7 -0.98 8.9592464E7 -6000000.0 -0.53 -1.063 -0.9576 3070436 PK04_103082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D23 compound treatment 1.05373023E8 8870000.0 0.77 9.5858645E7 262000.0 0.02 0.5578 0.728 3189676 PK04_103083 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 D24 compound treatment 1.07391048E8 1.09E7 0.94 1.0385914E8 8260000.0 0.72 1.1762 0.9916 3070437 PK04_103084 CN1CCC(=CC1C2CC2)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E01 mock treatment 1.04303695E8 7800000.0 0.67 1.01878461E8 6280000.0 0.55 0.8651 0.9949 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E02 mock treatment 1.04457048E8 7950000.0 0.69 9.6827488E7 1230000.0 0.11 0.5619 0.8082 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E03 compound treatment 9.763329E7 1130000.0 0.1 9.9630079E7 4030000.0 0.35 0.3185 0.8698 3189677 PK04_103085 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E04 compound treatment 9.2806791E7 -3700000.0 -0.32 8.995406E7 -5640000.0 -0.49 -0.575 -0.9778 3070438 PK04_103086 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E05 compound treatment 9.6716065E7 211000.0 0.02 9.8491786E7 2900000.0 0.25 0.1921 0.756 3189678 PK04_103087 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E06 compound treatment 9.159437E7 -4910000.0 -0.42 8.8567805E7 -7030000.0 -0.62 -0.7349 -0.9835 3189679 PK04_103088 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E07 compound treatment 9.625877E7 -246000.0 -0.02 9.2998964E7 -2600000.0 -0.23 -0.1758 -0.7699 3189680 PK04_103089 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E08 compound treatment 8.9222579E7 -7280000.0 -0.63 8.8487161E7 -7110000.0 -0.62 -0.8847 -1.0 3070490 PK04_103090 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E09 mock treatment 9.0551255E7 -5950000.0 -0.51 9.2167101E7 -3430000.0 -0.3 -0.5758 -0.9671 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E10 mock treatment 8.7533991E7 -8970000.0 -0.77 8.7328266E7 -8270000.0 -0.72 -1.0596 -0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E11 compound treatment 6.6899404E7 -2.96E7 -2.56 7.1940667E7 -2.37E7 -2.07 -3.2721 -0.9945 3187704 PK04_103091 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E12 compound treatment 8.3746454E7 -1.28E7 -1.1 9.0628324E7 -4970000.0 -0.43 -1.0867 -0.9173 3070491 PK04_103092 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E13 compound treatment 7.3395221E7 -2.31E7 -2.0 8.0429323E7 -1.52E7 -1.33 -2.35 -0.9804 3187705 PK04_103093 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E14 compound treatment 8.3066163E7 -1.34E7 -1.16 8.6765185E7 -8830000.0 -0.77 -1.3673 -0.9805 3187706 PK04_103094 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E15 compound treatment 9.0613148E7 -5890000.0 -0.51 9.4258066E7 -1340000.0 -0.12 -0.4427 -0.8477 3070492 PK04_103095 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E16 compound treatment 9.0962453E7 -5540000.0 -0.48 9.3056462E7 -2540000.0 -0.22 -0.4957 -0.9391 3187707 PK04_103096 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E17 mock treatment 9.5447328E7 -1060000.0 -0.09 1.01998559E8 6400000.0 0.56 0.3316 0.5841 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E18 mock treatment 8.4608072E7 -1.19E7 -1.03 1.00414604E8 4820000.0 0.42 -0.4284 -0.3857 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E19 compound treatment 8.4206454E7 -1.23E7 -1.06 8.6825528E7 -8770000.0 -0.77 -1.2939 -0.9873 3070493 PK04_103097 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E20 compound treatment 9.3522736E7 -2980000.0 -0.26 9.6936822E7 1340000.0 0.12 -0.0992 -0.3504 3187708 PK04_103098 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E21 compound treatment 8.4787531E7 -1.17E7 -1.01 8.8407509E7 -7190000.0 -0.63 -1.1605 -0.9738 3187709 PK04_103099 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E22 compound treatment 9.4609811E7 -1900000.0 -0.16 9.5567252E7 -29000.0 0.0 -0.1175 -0.718 3070494 PK04_103100 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E23 compound treatment 1.031603E8 6660000.0 0.57 1.0257835E8 6980000.0 0.61 0.8385 0.9995 3187710 PK04_103101 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 E24 compound treatment 1.05086107E8 8580000.0 0.74 1.0369892E8 8100000.0 0.71 1.0255 0.9998 3187711 PK04_103102 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F01 mock treatment 1.07262935E8 1.08E7 0.93 1.03595032E8 8000000.0 0.7 1.152 0.9903 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F02 mock treatment 1.02358157E8 5850000.0 0.51 9.9810552E7 4210000.0 0.37 0.6183 0.988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F03 compound treatment 9.8909483E7 2400000.0 0.21 9.9237032E7 3640000.0 0.32 0.3722 0.9785 3070495 PK04_103103 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F04 compound treatment 9.9315927E7 2810000.0 0.24 9.5451537E7 -145000.0 -0.01 0.1627 0.6693 3187712 PK04_103104 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F05 compound treatment 8.8790721E7 -7710000.0 -0.67 8.7806167E7 -7790000.0 -0.68 -0.9532 -0.9999 3070496 PK04_103105 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F06 compound treatment 9.297313E7 -3530000.0 -0.31 8.9209123E7 -6390000.0 -0.56 -0.611 -0.9594 3187713 PK04_103106 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F07 compound treatment 9.1556065E7 -4950000.0 -0.43 9.2038203E7 -3560000.0 -0.31 -0.5224 -0.9879 3070497 PK04_103107 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F08 compound treatment 9.1962721E7 -4540000.0 -0.39 9.2973026E7 -2620000.0 -0.23 -0.4398 -0.9674 3187714 PK04_103108 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F09 mock treatment 9.2885654E7 -3620000.0 -0.31 9.4125912E7 -1470000.0 -0.13 -0.312 -0.923 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F10 mock treatment 8.9987194E7 -6520000.0 -0.56 9.0013532E7 -5580000.0 -0.49 -0.7436 -0.9975 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F11 compound treatment 9.2086549E7 -4420000.0 -0.38 9.2087061E7 -3510000.0 -0.31 -0.487 -0.9942 3187715 PK04_103109 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F12 compound treatment 8.6939671E7 -9570000.0 -0.83 9.2873182E7 -2720000.0 -0.24 -0.7527 -0.8754 3070498 PK04_103110 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F13 compound treatment 8.5506606E7 -1.1E7 -0.95 9.0075565E7 -5520000.0 -0.48 -1.0134 -0.9508 3187716 PK04_103111 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F14 compound treatment 8.817807E7 -8330000.0 -0.72 9.2605953E7 -2990000.0 -0.26 -0.6936 -0.9063 3070499 PK04_103112 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F15 compound treatment 9.1409479E7 -5100000.0 -0.44 9.4927788E7 -668000.0 -0.06 -0.3526 -0.7941 3187717 PK04_103113 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F16 compound treatment 9.4107261E7 -2400000.0 -0.21 9.5784754E7 188000.0 0.02 -0.1348 -0.6487 3187718 PK04_103114 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F17 mock treatment 9.4161191E7 -2340000.0 -0.2 1.03429226E8 7830000.0 0.69 0.3416 0.4779 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F18 mock treatment 1.02492529E8 5990000.0 0.52 1.01875918E8 6280000.0 0.55 0.7543 0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F19 compound treatment 9.5273926E7 -1230000.0 -0.11 9.5609943E7 13700.0 0.0 -0.0743 -0.6991 3070500 PK04_103115 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F20 compound treatment 8.719038E7 -9310000.0 -0.8 9.1122432E7 -4470000.0 -0.39 -0.8457 -0.9452 3187719 PK04_103116 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F21 compound treatment 9.7932412E7 1430000.0 0.12 9.9103043E7 3510000.0 0.31 0.3042 0.9197 3070501 PK04_103117 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F22 compound treatment 8.3740584E7 -1.28E7 -1.1 8.5118477E7 -1.05E7 -0.92 -1.428 -0.9958 3187720 PK04_103118 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F23 compound treatment 1.03590513E8 7090000.0 0.61 1.03667274E8 8070000.0 0.71 0.9322 0.9974 3187721 PK04_103119 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 F24 compound treatment 1.0544965E8 8940000.0 0.77 1.03725978E8 8130000.0 0.71 1.0494 0.9992 3070502 PK04_103120 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G01 compound treatment 8.0396818E7 -1.61E7 -1.39 7.6053894E7 -1.95E7 -1.71 -2.1932 -0.9948 3187722 PK04_103121 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G02 compound treatment 1.01025952E8 4520000.0 0.39 9.5129888E7 -466000.0 -0.04 0.2473 0.6298 3187723 PK04_103122 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G03 mock treatment 1.00924114E8 4420000.0 0.38 9.9646042E7 4050000.0 0.35 0.5205 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G04 mock treatment 9.6740369E7 235000.0 0.02 9.3522736E7 -2070000.0 -0.18 -0.1139 -0.624 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G05 compound treatment 8.3843834E7 -1.27E7 -1.09 8.3861072E7 -1.17E7 -1.03 -1.4995 -0.9995 3070503 PK04_103123 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G06 compound treatment 9.3182102E7 -3320000.0 -0.29 8.8660527E7 -6940000.0 -0.61 -0.6322 -0.9415 3187724 PK04_103124 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G07 compound treatment 6.7978534E7 -2.85E7 -2.46 7.4354395E7 -2.12E7 -1.86 -3.0568 -0.9904 3070504 PK04_103125 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G08 compound treatment 8.6463713E7 -1.0E7 -0.87 8.8278925E7 -7320000.0 -0.64 -1.0661 -0.9889 3187725 PK04_103126 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G09 compound treatment 9.1271505E7 -5230000.0 -0.45 9.3266639E7 -2330000.0 -0.2 -0.4638 -0.9353 3187726 PK04_103127 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G10 compound treatment 8.6818389E7 -9690000.0 -0.84 8.5103537E7 -1.05E7 -0.92 -1.2409 -0.9989 3070543 PK04_103128 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G11 compound treatment 9.137597E7 -5130000.0 -0.44 9.5433906E7 -162000.0 -0.01 -0.3233 -0.7294 3187727 PK04_103129 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G12 compound treatment 8.659936E7 -9910000.0 -0.86 8.7776457E7 -7820000.0 -0.68 -1.0889 -0.9939 3187844 PK04_103130 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G13 compound treatment 9.2733922E7 -3770000.0 -0.33 9.4193158E7 -1400000.0 -0.12 -0.3172 -0.9111 3070544 PK04_103131 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G14 compound treatment 8.8775492E7 -7730000.0 -0.67 9.1313628E7 -4280000.0 -0.37 -0.7371 -0.9627 3187845 PK04_103132 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G15 compound treatment 9.6153104E7 -352000.0 -0.03 9.3528887E7 -2070000.0 -0.18 -0.1494 -0.8145 3070545 PK04_103133 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G16 compound treatment 9.204188E7 -4460000.0 -0.39 9.3708859E7 -1890000.0 -0.17 -0.3894 -0.9285 3187846 PK04_103134 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G17 compound treatment 9.0185449E7 -6320000.0 -0.55 9.0679615E7 -4920000.0 -0.43 -0.6902 -0.9931 3070546 PK04_103135 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G18 compound treatment 9.1166751E7 -5340000.0 -0.46 8.8303827E7 -7290000.0 -0.64 -0.7773 -0.9873 3187847 PK04_103136 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G19 mock treatment 9.9769437E7 3260000.0 0.28 9.4960183E7 -636000.0 -0.06 0.16 0.5567 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G20 mock treatment 9.8051811E7 1550000.0 0.13 1.01806126E8 6210000.0 0.54 0.4788 0.8555 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G21 compound treatment 1.00284755E8 3780000.0 0.33 1.02438326E8 6840000.0 0.6 0.6543 0.9593 3070547 PK04_103137 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G22 compound treatment 9.6897947E7 393000.0 0.03 9.50246E7 -572000.0 -0.05 -0.0114 -0.1883 3187848 PK04_103138 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G23 compound treatment 1.07615783E8 1.11E7 0.96 1.05857096E8 1.03E7 0.9 1.3136 0.9994 3070548 PK04_103139 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 G24 compound treatment 1.07042023E8 1.05E7 0.91 1.02074609E8 6480000.0 0.57 1.0444 0.9741 3187849 PK04_103140 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H01 compound treatment 9.0453285E7 -6050000.0 -0.52 8.782189E7 -7770000.0 -0.68 -0.8507 -0.9915 3070549 PK04_103141 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H02 compound treatment 9.8704768E7 2200000.0 0.19 9.6184004E7 588000.0 0.05 0.1707 0.8673 3187850 PK04_103142 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H03 mock treatment 1.00296657E8 3790000.0 0.33 9.9928871E7 4330000.0 0.38 0.4997 0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H04 mock treatment 9.5942026E7 -563000.0 -0.05 8.9329469E7 -6270000.0 -0.55 -0.4222 -0.7668 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H05 compound treatment 9.8303312E7 1800000.0 0.16 9.8542378E7 2950000.0 0.26 0.2921 0.9706 3187851 PK04_103143 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H06 compound treatment 8.8689989E7 -7820000.0 -0.68 9.5102635E7 -494000.0 -0.04 -0.5078 -0.7508 3187852 PK04_103144 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H07 compound treatment 9.6620273E7 115000.0 0.01 9.6895186E7 1300000.0 0.11 0.0874 0.7661 3070550 PK04_103145 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H08 compound treatment 9.1208122E7 -5300000.0 -0.46 9.4326629E7 -1270000.0 -0.11 -0.4021 -0.854 3187853 PK04_103146 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H09 compound treatment 9.7427464E7 922000.0 0.08 9.7036687E7 1440000.0 0.13 0.1455 0.9755 3070551 PK04_103147 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H10 compound treatment 9.3312835E7 -3190000.0 -0.28 8.7793052E7 -7800000.0 -0.68 -0.6779 -0.9204 3070552 PK04_103148 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H11 compound treatment 9.2402007E7 -4100000.0 -0.35 9.5186963E7 -409000.0 -0.04 -0.2759 -0.7746 3187854 PK04_103149 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H12 compound treatment 8.8645275E7 -7860000.0 -0.68 8.9810129E7 -5790000.0 -0.51 -0.8381 -0.9896 3070553 PK04_103150 CN1CCC(=CC1c2cccs2)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H13 compound treatment 9.6672285E7 167000.0 0.01 9.6869339E7 1270000.0 0.11 0.089 0.7921 3187855 PK04_103151 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H14 compound treatment 9.063148E7 -5870000.0 -0.51 9.0797737E7 -4800000.0 -0.42 -0.6557 -0.9956 3187856 PK04_103152 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H15 compound treatment 9.3812668E7 -2690000.0 -0.23 9.6548091E7 952000.0 0.08 -0.1055 -0.4272 3070554 PK04_103153 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H16 compound treatment 9.1192771E7 -5310000.0 -0.46 9.2699593E7 -2900000.0 -0.25 -0.5037 -0.9609 3187857 PK04_103154 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H17 compound treatment 9.2319158E7 -4190000.0 -0.36 9.4096915E7 -1500000.0 -0.13 -0.3484 -0.9059 3187858 PK04_103155 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H18 compound treatment 9.128739E7 -5220000.0 -0.45 8.9119872E7 -6480000.0 -0.57 -0.7195 -0.9935 3070555 PK04_103156 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H19 mock treatment 9.9300358E7 2800000.0 0.24 1.01893385E8 6300000.0 0.55 0.5604 0.9314 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H20 mock treatment 9.8460511E7 1960000.0 0.17 9.8607536E7 3010000.0 0.26 0.3058 0.9769 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H21 compound treatment 1.05817231E8 9310000.0 0.8 1.02616452E8 7020000.0 0.61 1.0032 0.9912 3187859 PK04_103157 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H22 compound treatment 1.02515692E8 6010000.0 0.52 1.00824312E8 5230000.0 0.46 0.6906 0.998 3070556 PK04_103158 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H23 compound treatment 1.01502005E8 5000000.0 0.43 9.1205864E7 -4390000.0 -0.38 0.0335 0.058 3187860 PK04_103159 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 H24 compound treatment 1.03570591E8 7070000.0 0.61 1.01780318E8 6180000.0 0.54 0.8142 0.9982 3070597 PK04_103160 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I01 compound treatment 1.06483106E8 9980000.0 0.86 1.03346422E8 7750000.0 0.68 1.089 0.993 3187861 PK04_103161 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I02 compound treatment 1.04448492E8 7940000.0 0.69 9.8135065E7 2540000.0 0.22 0.6423 0.8906 3187862 PK04_103162 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I03 compound treatment 1.00819323E8 4310000.0 0.37 9.9272146E7 3680000.0 0.32 0.491 0.9973 3070598 PK04_103163 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I04 compound treatment 9.8647322E7 2140000.0 0.19 9.409936E7 -1500000.0 -0.13 0.0382 0.1685 3187863 PK04_103164 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I05 mock treatment 9.6459131E7 -45900.0 0.0 9.72187E7 1620000.0 0.14 0.0976 0.6871 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I06 mock treatment 9.5525733E7 -979000.0 -0.08 9.3309718E7 -2290000.0 -0.2 -0.2013 -0.9266 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I07 compound treatment 9.7538147E7 1030000.0 0.09 9.7629946E7 2030000.0 0.18 0.1889 0.949 3070599 PK04_103165 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I08 compound treatment 9.3024731E7 -3480000.0 -0.3 9.16058E7 -3990000.0 -0.35 -0.4595 -0.9972 3187864 PK04_103166 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I09 compound treatment 9.6414358E7 -90700.0 -0.01 9.4108694E7 -1490000.0 -0.13 -0.0976 -0.7483 3187865 PK04_103167 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I10 compound treatment 9.4476997E7 -2030000.0 -0.18 9.0721211E7 -4880000.0 -0.43 -0.4256 -0.9227 3070600 PK04_103168 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I11 compound treatment 9.5081876E7 -1420000.0 -0.12 9.2950022E7 -2650000.0 -0.23 -0.2507 -0.9561 3187866 PK04_103169 COCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I12 compound treatment 8.8445207E7 -8060000.0 -0.7 9.1119944E7 -4480000.0 -0.39 -0.7693 -0.963 3187978 PK04_103170 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I13 compound treatment 9.633352E7 -172000.0 -0.01 9.6258986E7 663000.0 0.06 0.0305 0.5101 3070601 PK04_103171 CCCCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I14 compound treatment 9.0753307E7 -5750000.0 -0.5 9.2527105E7 -3070000.0 -0.27 -0.5412 -0.9583 3187979 PK04_103172 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I15 compound treatment 9.4297273E7 -2210000.0 -0.19 9.5200476E7 -396000.0 -0.03 -0.1593 -0.8221 3070602 PK04_103173 CC(C)C(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I16 compound treatment 8.5147481E7 -1.14E7 -0.98 8.4954965E7 -1.06E7 -0.93 -1.3522 -0.9997 3187980 PK04_103174 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I17 compound treatment 9.4830375E7 -1670000.0 -0.14 9.650059E7 904000.0 0.08 -0.0463 -0.2809 3070603 PK04_103175 COCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I18 compound treatment 9.1320486E7 -5180000.0 -0.45 9.8826241E7 3230000.0 0.28 -0.1168 -0.2205 3187981 PK04_103176 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I19 compound treatment 9.5559964E7 -945000.0 -0.08 9.6906235E7 1310000.0 0.11 0.0233 0.1659 3070604 PK04_103177 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I20 compound treatment 9.5131923E7 -1370000.0 -0.12 9.6083344E7 487000.0 0.04 -0.0537 -0.4263 3187982 PK04_103178 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I21 mock treatment 1.00237419E8 3730000.0 0.32 1.03513775E8 7920000.0 0.69 0.7179 0.9394 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I22 mock treatment 9.8076215E7 1570000.0 0.14 1.00260927E8 4660000.0 0.41 0.3846 0.8941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I23 compound treatment 8.0393185E7 -1.61E7 -1.39 8.1875876E7 -1.37E7 -1.2 -1.8331 -0.9973 3187983 PK04_103179 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 I24 compound treatment 1.00082605E8 3580000.0 0.31 1.00321533E8 4730000.0 0.41 0.5109 0.9897 3070605 PK04_103180 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J01 compound treatment 9.6383679E7 -121000.0 -0.01 8.5890951E7 -9710000.0 -0.85 -0.608 -0.7158 3187984 PK04_103181 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J02 compound treatment 9.826517E7 1760000.0 0.15 9.8236022E7 2640000.0 0.23 0.2709 0.9794 3187985 PK04_103182 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J03 compound treatment 9.8614909E7 2110000.0 0.18 9.5650599E7 54300.0 0.0 0.1322 0.7253 3070606 PK04_103183 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J04 compound treatment 9.4804273E7 -1700000.0 -0.15 9.4010201E7 -1590000.0 -0.14 -0.202 -0.9996 3187986 PK04_103184 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J05 mock treatment 9.957393E7 3070000.0 0.27 9.6805895E7 1210000.0 0.11 0.2623 0.9189 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J06 mock treatment 9.2399799E7 -4110000.0 -0.35 9.0397861E7 -5200000.0 -0.45 -0.5724 -0.9924 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J07 compound treatment 8.3407865E7 -1.31E7 -1.13 7.7073238E7 -1.85E7 -1.62 -1.9462 -0.9845 3187987 PK04_103185 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J08 compound treatment 4.4639185E7 -5.19E7 -4.48 3.6605065E7 -5.9E7 -5.16 -6.8183 -0.9975 3070607 PK04_103186 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J09 compound treatment 9.8584126E7 2080000.0 0.18 9.7181259E7 1590000.0 0.14 0.2251 0.9919 3187988 PK04_103187 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J10 compound treatment 9.1418791E7 -5090000.0 -0.44 9.0219669E7 -5380000.0 -0.47 -0.6434 -0.9994 3070608 PK04_103188 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J11 compound treatment 9.7735227E7 1230000.0 0.11 9.6227735E7 631000.0 0.06 0.1142 0.9536 3187989 PK04_103189 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J12 compound treatment 9.1043945E7 -5460000.0 -0.47 9.2103049E7 -3490000.0 -0.31 -0.5497 -0.978 3070609 PK04_103190 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J13 compound treatment 9.5895518E7 -610000.0 -0.05 9.51085E7 -488000.0 -0.04 -0.0674 -0.9946 3187990 PK04_103191 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J14 compound treatment 9.5153039E7 -1350000.0 -0.12 9.2666189E7 -2930000.0 -0.26 -0.2639 -0.9366 3187991 PK04_103192 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J15 compound treatment 8.4556105E7 -1.19E7 -1.03 8.4315241E7 -1.13E7 -0.99 -1.4279 -0.9998 3070610 PK04_103193 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J16 compound treatment 9.5158052E7 -1350000.0 -0.12 9.3422064E7 -2170000.0 -0.19 -0.2168 -0.9721 3187992 PK04_103194 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J17 compound treatment 9.1675942E7 -4830000.0 -0.42 9.314909E7 -2450000.0 -0.21 -0.4464 -0.952 3070654 PK04_103195 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J18 compound treatment 9.4343889E7 -2160000.0 -0.19 9.4842866E7 -753000.0 -0.07 -0.1786 -0.9022 3187993 PK04_103196 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J19 compound treatment 1.00215581E8 3710000.0 0.32 1.00920548E8 5320000.0 0.47 0.5561 0.9833 3070655 PK04_103197 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J20 compound treatment 9.6768509E7 263000.0 0.02 9.6841596E7 1250000.0 0.11 0.0932 0.8367 3187994 PK04_103198 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J21 mock treatment 1.01020805E8 4520000.0 0.39 1.03775206E8 8180000.0 0.72 0.7819 0.9592 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J22 mock treatment 9.8068733E7 1560000.0 0.14 9.8492309E7 2900000.0 0.25 0.2747 0.9566 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J23 compound treatment 6.4655679E7 -3.18E7 -2.75 5.9468308E7 -3.61E7 -3.16 -4.1809 -0.9976 3187995 PK04_103199 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 J24 compound treatment 1.05358194E8 8850000.0 0.76 1.04218672E8 8620000.0 0.75 1.0743 1.0 3070656 PK04_103200 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K01 compound treatment 1.06392379E8 9890000.0 0.85 1.04837976E8 9240000.0 0.81 1.1758 0.9996 3187996 PK04_103201 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K02 compound treatment 9.8162618E7 1660000.0 0.14 9.6733518E7 1140000.0 0.1 0.1716 0.9842 3187997 PK04_103202 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K03 compound treatment 9.9511793E7 3010000.0 0.26 9.5893218E7 297000.0 0.03 0.202 0.774 3070657 PK04_103203 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K04 compound treatment 9.9970856E7 3470000.0 0.3 9.2738311E7 -2860000.0 -0.25 0.0348 0.0892 3187998 PK04_103204 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K05 compound treatment 9.1749141E7 -4760000.0 -0.41 1.01023116E8 5430000.0 0.47 0.0454 0.0723 3070658 PK04_103205 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K06 compound treatment 9.2000687E7 -4500000.0 -0.39 9.5974488E7 378000.0 0.03 -0.2517 -0.6446 3187999 PK04_103206 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K07 mock treatment 9.4207958E7 -2300000.0 -0.2 9.646961E7 873000.0 0.08 -0.0862 -0.4056 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K08 mock treatment 9.5648173E7 -857000.0 -0.07 9.1491258E7 -4110000.0 -0.36 -0.3064 -0.8352 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K09 compound treatment 9.3114187E7 -3390000.0 -0.29 9.808726E7 2490000.0 0.22 -0.0529 -0.145 3188000 PK04_103207 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K10 compound treatment 9.3630339E7 -2870000.0 -0.25 8.9874635E7 -5720000.0 -0.5 -0.5297 -0.9476 3070659 PK04_103208 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K11 compound treatment 9.3127442E7 -3380000.0 -0.29 9.0775395E7 -4820000.0 -0.42 -0.5046 -0.9838 3188108 PK04_103209 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K12 compound treatment 8.4991986E7 -1.15E7 -0.99 8.4941389E7 -1.07E7 -0.93 -1.3625 -0.9995 3188109 PK04_103210 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K13 compound treatment 9.5709705E7 -795000.0 -0.07 9.1996028E7 -3600000.0 -0.32 -0.2714 -0.8415 3070660 PK04_103211 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K14 compound treatment 9.4521981E7 -1980000.0 -0.17 9.3527295E7 -2070000.0 -0.18 -0.2492 -0.9996 3188110 PK04_103212 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K15 mock treatment 9.5744818E7 -760000.0 -0.07 8.9319956E7 -6280000.0 -0.55 -0.4348 -0.786 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K16 mock treatment 9.0901122E7 -5600000.0 -0.48 9.1099567E7 -4500000.0 -0.39 -0.6205 -0.9947 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K17 compound treatment 1.01734675E8 5230000.0 0.45 9.7575006E7 1980000.0 0.17 0.4418 0.9134 3070661 PK04_103213 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K18 compound treatment 9.8874056E7 2370000.0 0.2 9.4414982E7 -1180000.0 -0.1 0.0716 0.3122 3188111 PK04_103214 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K19 compound treatment 9.9535809E7 3030000.0 0.26 9.966874E7 4070000.0 0.36 0.4371 0.9885 3188112 PK04_103215 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K20 compound treatment 1.01409303E8 4900000.0 0.42 9.9452762E7 3860000.0 0.34 0.5382 0.9937 3070662 PK04_103216 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K21 compound treatment 8.5728352E7 -1.08E7 -0.93 8.5033847E7 -1.06E7 -0.92 -1.3118 -1.0 3188113 PK04_103217 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K22 compound treatment 1.03039185E8 6530000.0 0.56 9.5988323E7 392000.0 0.03 0.4233 0.7487 3188114 PK04_103218 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K23 mock treatment 1.0746889E8 1.1E7 0.95 1.09424829E8 1.38E7 1.21 1.5254 0.9926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 K24 mock treatment 1.00266618E8 3760000.0 0.32 1.07289756E8 1.17E7 1.02 0.9534 0.8879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L01 compound treatment 8.8854645E7 -7650000.0 -0.66 9.236139E7 -3230000.0 -0.28 -0.6674 -0.9284 3070663 PK04_103219 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L02 compound treatment 1.00320609E8 3820000.0 0.33 9.5209094E7 -387000.0 -0.03 0.2091 0.6311 3188115 PK04_103220 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L03 compound treatment 9.0117994E7 -6390000.0 -0.55 8.8052309E7 -7540000.0 -0.66 -0.8569 -0.996 3070664 PK04_103221 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L04 compound treatment 9.6233786E7 -271000.0 -0.02 9.5520624E7 -75600.0 -0.01 -0.0212 -0.8727 3188116 PK04_103222 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L05 compound treatment 8.4912597E7 -1.16E7 -1.0 8.7290425E7 -8310000.0 -0.73 -1.222 -0.9876 3070665 PK04_103223 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L06 compound treatment 9.1318445E7 -5190000.0 -0.45 9.1855525E7 -3740000.0 -0.33 -0.5483 -0.9881 3188117 PK04_103224 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L07 mock treatment 1.01320895E8 4820000.0 0.42 9.6373633E7 777000.0 0.07 0.3422 0.812 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L08 mock treatment 9.2130454E7 -4370000.0 -0.38 9.5993015E7 397000.0 0.03 -0.2426 -0.6394 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L09 compound treatment 9.0422016E7 -6080000.0 -0.53 9.4424122E7 -1170000.0 -0.1 -0.4441 -0.8295 3188118 PK04_103225 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L10 compound treatment 9.5418943E7 -1090000.0 -0.09 9.5624333E7 28100.0 0.0 -0.0646 -0.6884 3188119 PK04_103226 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L11 compound treatment 7.3243983E7 -2.33E7 -2.01 6.855584E7 -2.7E7 -2.37 -3.094 -0.9967 3070666 PK04_103227 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L12 compound treatment 8.7613689E7 -8890000.0 -0.77 8.4811098E7 -1.08E7 -0.94 -1.2105 -0.9948 3188120 PK04_103228 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L13 compound treatment 9.6551505E7 46400.0 0.0 9.2965602E7 -2630000.0 -0.23 -0.16 -0.6947 3188121 PK04_103229 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L14 compound treatment 7.1209487E7 -2.53E7 -2.18 7.239302E7 -2.32E7 -2.03 -2.9808 -0.9993 3188122 PK04_103230 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L15 mock treatment 1.00120553E8 3620000.0 0.31 9.2133003E7 -3460000.0 -0.3 0.0065 0.0149 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L16 mock treatment 9.871228E7 2210000.0 0.19 9.270228E7 -2890000.0 -0.25 -0.0443 -0.1397 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L17 compound treatment 9.6404492E7 -101000.0 -0.01 1.00299945E8 4700000.0 0.41 0.2849 0.692 3070709 PK04_103231 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L18 compound treatment 9.0905651E7 -5600000.0 -0.48 8.9382591E7 -6210000.0 -0.54 -0.7265 -0.9983 3188123 PK04_103232 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L19 compound treatment 1.03067455E8 6560000.0 0.57 1.01725187E8 6130000.0 0.54 0.7801 0.9996 3070710 PK04_103233 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L20 compound treatment 7.341341E7 -2.31E7 -1.99 7.5830079E7 -1.98E7 -1.73 -2.6335 -0.9975 3188124 PK04_103234 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L21 compound treatment 1.08107833E8 1.16E7 1.0 1.0905981E8 1.35E7 1.18 1.5418 0.9968 3070711 PK04_103235 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L22 compound treatment 1.03032485E8 6530000.0 0.56 9.8203264E7 2610000.0 0.23 0.56 0.9207 3188125 PK04_103236 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L23 mock treatment 1.12448926E8 1.59E7 1.38 1.07652811E8 1.21E7 1.06 1.7199 0.9914 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 L24 mock treatment 1.05257491E8 8750000.0 0.76 1.04917918E8 9320000.0 0.82 1.1114 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M01 compound treatment 1.04012062E8 7510000.0 0.65 9.8980038E7 3380000.0 0.3 0.6679 0.937 3070712 PK04_103237 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M02 compound treatment 9.7267358E7 762000.0 0.07 9.9493978E7 3900000.0 0.34 0.2878 0.8283 3188126 PK04_103238 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M03 compound treatment 1.02990857E8 6490000.0 0.56 9.4948066E7 -648000.0 -0.06 0.356 0.6323 3070713 PK04_103239 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M04 compound treatment 1.00127791E8 3620000.0 0.31 9.5809899E7 214000.0 0.02 0.2345 0.748 3188127 PK04_103240 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M05 compound treatment 9.2134976E7 -4370000.0 -0.38 1.01281153E8 5680000.0 0.5 0.0849 0.136 3188128 PK04_103241 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M06 compound treatment 1.0093314E8 4430000.0 0.38 8.7739857E7 -7860000.0 -0.69 -0.2157 -0.2742 3070714 PK04_103242 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M07 compound treatment 1.0037663E8 3870000.0 0.33 1.02852896E8 7260000.0 0.64 0.6855 0.9551 3188237 PK04_103243 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M08 compound treatment 8.6296718E7 -1.02E7 -0.88 9.0934388E7 -4660000.0 -0.41 -0.912 -0.9387 3070715 PK04_103244 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M09 mock treatment 1.00846674E8 4340000.0 0.37 9.0814128E7 -4780000.0 -0.42 -0.0308 -0.0548 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M10 mock treatment 9.8166052E7 1660000.0 0.14 9.4577976E7 -1020000.0 -0.09 0.0384 0.2275 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M11 compound treatment 8.890628E7 -7600000.0 -0.66 9.6756815E7 1160000.0 0.1 -0.3923 -0.5906 3188238 PK04_103245 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M12 compound treatment 9.1783961E7 -4720000.0 -0.41 8.3584259E7 -1.2E7 -1.05 -1.0317 -0.915 3188239 PK04_103246 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M13 mock treatment 9.6702897E7 198000.0 0.02 9.8915454E7 3320000.0 0.29 0.2175 0.7474 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M14 mock treatment 8.896693E7 -7540000.0 -0.65 9.5267674E7 -329000.0 -0.03 -0.4807 -0.7376 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M15 compound treatment 9.0263585E7 -6240000.0 -0.54 9.0420794E7 -5180000.0 -0.45 -0.7015 -0.9963 3070716 PK04_103247 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M16 compound treatment 9.2595571E7 -3910000.0 -0.34 9.1494314E7 -4100000.0 -0.36 -0.4926 -0.9995 3188240 PK04_103248 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M17 compound treatment 8.8961598E7 -7540000.0 -0.65 9.2903726E7 -2690000.0 -0.24 -0.6273 -0.9054 3070717 PK04_103249 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M18 compound treatment 9.2129464E7 -4380000.0 -0.38 8.8521423E7 -7070000.0 -0.62 -0.7051 -0.972 3188241 PK04_103250 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M19 compound treatment 1.04884581E8 8380000.0 0.72 9.9393423E7 3800000.0 0.33 0.7468 0.9377 3188242 PK04_103251 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M20 compound treatment 9.3927147E7 -2580000.0 -0.22 9.3351119E7 -2250000.0 -0.2 -0.2964 -0.9981 3070718 PK04_103252 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M21 compound treatment 9.8776767E7 2270000.0 0.2 9.5664069E7 67800.0 0.01 0.1429 0.7282 3188243 PK04_103253 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M22 compound treatment 8.8863548E7 -7640000.0 -0.66 8.844352E7 -7150000.0 -0.63 -0.9093 -0.9997 3188244 PK04_103254 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M23 compound treatment 1.08692843E8 1.22E7 1.05 1.05099916E8 9500000.0 0.83 1.3325 0.9932 3188245 PK04_103255 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 M24 compound treatment 1.01575392E8 5070000.0 0.44 9.8504925E7 2910000.0 0.25 0.4897 0.9667 3070768 PK04_103256 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N01 compound treatment 1.09840328E8 1.33E7 1.15 1.01939112E8 6340000.0 0.56 1.207 0.944 3188246 PK04_103257 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N02 compound treatment 9.02083E7 -6300000.0 -0.54 9.922196E7 3630000.0 0.32 -0.1602 -0.2544 3188247 PK04_103258 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N03 compound treatment 1.07105998E8 1.06E7 0.92 1.02839251E8 7240000.0 0.63 1.0957 0.9839 3070772 PK04_103259 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N04 compound treatment 1.00661626E8 4160000.0 0.36 8.9336541E7 -6260000.0 -0.55 -0.1335 -0.2038 3188248 PK04_103260 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N05 compound treatment 8.8146415E7 -8360000.0 -0.72 1.03114798E8 7520000.0 0.66 -0.0452 -0.0463 3188249 PK04_103261 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N06 compound treatment 7.3418382E7 -2.31E7 -1.99 7.4828979E7 -2.08E7 -1.82 -2.6952 -0.9989 3188250 PK04_103262 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N07 compound treatment 1.04224261E8 7720000.0 0.67 9.2267247E7 -3330000.0 -0.29 0.2654 0.3648 3070060 PK04_103263 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N08 compound treatment 8.8459076E7 -8050000.0 -0.69 9.5014343E7 -582000.0 -0.05 -0.5274 -0.7569 3188251 PK04_103264 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N09 mock treatment 1.02853377E8 6350000.0 0.55 1.01550033E8 5950000.0 0.52 0.7562 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N10 mock treatment 9.5467359E7 -1040000.0 -0.09 8.8610115E7 -6990000.0 -0.61 -0.4957 -0.8022 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N11 compound treatment 9.2402732E7 -4100000.0 -0.35 9.8279266E7 2680000.0 0.23 -0.0845 -0.1988 3070061 PK04_103265 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N12 compound treatment 8.6565331E7 -9940000.0 -0.86 9.2002496E7 -3590000.0 -0.31 -0.8295 -0.9072 3188252 PK04_103266 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N13 mock treatment 9.6946306E7 441000.0 0.04 8.2509845E7 -1.31E7 -1.15 -0.7829 -0.6832 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N14 mock treatment 8.991051E7 -6590000.0 -0.57 9.5415291E7 -181000.0 -0.02 -0.414 -0.7265 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N15 compound treatment 1.0269444E8 6190000.0 0.53 1.00547816E8 4950000.0 0.43 0.6844 0.9946 3070062 PK04_103267 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N16 compound treatment 9.5872143E7 -633000.0 -0.05 8.6396653E7 -9200000.0 -0.81 -0.608 -0.7534 3188253 PK04_103268 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N17 compound treatment 9.4736977E7 -1770000.0 -0.15 9.9111361E7 3520000.0 0.31 0.1095 0.319 3070063 PK04_103269 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N18 compound treatment 9.5888668E7 -616000.0 -0.05 9.7100825E7 1500000.0 0.13 0.0555 0.3905 3188254 PK04_103270 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N19 compound treatment 1.06071328E8 9570000.0 0.83 9.5832694E7 236000.0 0.02 0.5989 0.7246 3070064 PK04_103271 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N20 compound treatment 9.6501869E7 -3200.0 0.0 9.4795375E7 -801000.0 -0.07 -0.0498 -0.7099 3188255 PK04_103272 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N21 compound treatment 8.4525262E7 -1.2E7 -1.03 1.00339354E8 4740000.0 0.42 -0.4381 -0.393 3070065 PK04_103273 CCCCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N22 compound treatment 1.02998349E8 6490000.0 0.56 9.4192326E7 -1400000.0 -0.12 0.3097 0.5394 3188256 PK04_103274 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N23 compound treatment 9.7697269E7 1190000.0 0.1 1.1167422E8 1.61E7 1.41 1.0678 0.7568 3070066 PK04_103275 CC(C)C(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 N24 compound treatment 1.01293054E8 4790000.0 0.41 1.05015701E8 9420000.0 0.82 0.8753 0.9491 3188257 PK04_103276 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O01 compound treatment 1.04269949E8 7760000.0 0.67 1.04516133E8 8920000.0 0.78 1.0262 0.9971 3188258 PK04_103277 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O02 compound treatment 9.3477058E7 -3030000.0 -0.26 9.3444735E7 -2150000.0 -0.19 -0.3181 -0.987 3070067 PK04_103278 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O03 compound treatment 9.0367075E7 -6140000.0 -0.53 1.03364362E8 7770000.0 0.68 0.1058 0.1228 3188259 PK04_103279 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O04 compound treatment 9.5830784E7 -674000.0 -0.06 9.1947653E7 -3650000.0 -0.32 -0.267 -0.8225 3188369 PK04_103280 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O05 compound treatment 1.05831375E8 9330000.0 0.81 1.0188485E8 6290000.0 0.55 0.9588 0.9827 3070068 PK04_103281 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O06 compound treatment 9.9101702E7 2600000.0 0.22 9.380516E7 -1790000.0 -0.16 0.0477 0.1745 3188370 PK04_103282 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O07 compound treatment 1.03311699E8 6810000.0 0.59 1.02496671E8 6900000.0 0.6 0.8427 0.9999 3070069 PK04_103283 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O08 compound treatment 9.3415364E7 -3090000.0 -0.27 9.039957E7 -5200000.0 -0.45 -0.5103 -0.9677 3188371 PK04_103284 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O09 compound treatment 1.02866263E8 6360000.0 0.55 9.4805637E7 -791000.0 -0.07 0.3396 0.6132 3188372 PK04_103285 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O10 compound treatment 9.0854011E7 -5650000.0 -0.49 8.7208356E7 -8390000.0 -0.73 -0.8642 -0.9803 3070070 PK04_103286 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O11 mock treatment 9.9159447E7 2650000.0 0.23 9.5527731E7 -68500.0 -0.01 0.1579 0.6884 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O12 mock treatment 9.5604575E7 -900000.0 -0.08 9.3313975E7 -2280000.0 -0.2 -0.1962 -0.9155 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O13 compound treatment 9.6881305E7 376000.0 0.03 1.00455162E8 4860000.0 0.43 0.3237 0.7589 3188373 PK04_103287 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O14 compound treatment 8.8614176E7 -7890000.0 -0.68 8.8838504E7 -6760000.0 -0.59 -0.9001 -0.9975 3188374 PK04_103288 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O15 compound treatment 9.5511353E7 -994000.0 -0.09 9.5937805E7 342000.0 0.03 -0.0396 -0.4352 3070071 PK04_103289 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O16 compound treatment 8.430527E7 -1.22E7 -1.05 8.5380629E7 -1.02E7 -0.89 -1.3773 -0.9967 3188375 PK04_103290 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O17 compound treatment 9.7159778E7 655000.0 0.06 9.5143877E7 -452000.0 -0.04 0.012 0.1737 3070072 PK04_103291 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O18 compound treatment 9.4310211E7 -2190000.0 -0.19 9.0057751E7 -5540000.0 -0.48 -0.4768 -0.9161 3188376 PK04_103292 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O19 compound treatment 1.04757649E8 8250000.0 0.71 1.02005006E8 6410000.0 0.56 0.9006 0.993 3188377 PK04_103293 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O20 compound treatment 9.4268096E7 -2240000.0 -0.19 9.3592584E7 -2000000.0 -0.18 -0.2606 -0.9988 3070073 PK04_103294 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O21 compound treatment 1.0723774E8 1.07E7 0.93 1.08324041E8 1.27E7 1.11 1.4431 0.9958 3188378 PK04_103295 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O22 compound treatment 8.880971E7 -7700000.0 -0.66 9.1392336E7 -4200000.0 -0.37 -0.7301 -0.9611 3188379 PK04_103296 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O23 compound treatment 1.10683665E8 1.42E7 1.22 1.12607941E8 1.7E7 1.49 1.9187 0.9953 3070074 PK04_103297 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 O24 compound treatment 1.09213444E8 1.27E7 1.1 1.04977475E8 9380000.0 0.82 1.3567 0.9898 3188380 PK04_103298 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P01 compound treatment 1.05477569E8 8970000.0 0.77 9.8021784E7 2430000.0 0.21 0.6981 0.8688 3070075 PK04_103299 COCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P02 compound treatment 1.00472281E8 3970000.0 0.34 9.9528293E7 3930000.0 0.34 0.4856 1.0 3188381 PK04_103300 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P03 compound treatment 9.2333297E7 -4170000.0 -0.36 9.4848648E7 -748000.0 -0.07 -0.3011 -0.8221 3188382 PK04_103301 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P04 compound treatment 9.9048131E7 2540000.0 0.22 9.7097815E7 1500000.0 0.13 0.2482 0.9698 3070118 PK04_103302 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P05 compound treatment 9.7997293E7 1490000.0 0.13 9.7174834E7 1580000.0 0.14 0.1888 0.9994 3188383 PK04_103303 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P06 compound treatment 1.00028733E8 3520000.0 0.3 9.7939026E7 2340000.0 0.21 0.3602 0.9815 3070119 PK04_103304 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P07 compound treatment 1.06415043E8 9910000.0 0.86 1.00221598E8 4630000.0 0.4 0.8915 0.9415 3188384 PK04_103305 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P08 compound treatment 9.7995195E7 1490000.0 0.13 9.5259505E7 -337000.0 -0.03 0.0702 0.5314 3188385 PK04_103306 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P09 compound treatment 9.7148651E7 644000.0 0.06 9.2304083E7 -3290000.0 -0.29 -0.1644 -0.5603 3070120 PK04_103307 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P10 compound treatment 9.2580963E7 -3920000.0 -0.34 8.8429355E7 -7170000.0 -0.63 -0.6832 -0.9582 3188386 PK04_103308 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P11 mock treatment 9.8662023E7 2160000.0 0.19 9.8569986E7 2970000.0 0.26 0.3158 0.9866 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P12 mock treatment 9.9004216E7 2500000.0 0.22 9.5572627E7 -23600.0 0.0 0.1512 0.7003 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P13 compound treatment 1.00088984E8 3580000.0 0.31 9.6917658E7 1320000.0 0.12 0.3007 0.9099 3070121 PK04_103309 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P14 compound treatment 9.9651162E7 3150000.0 0.27 9.6285993E7 690000.0 0.06 0.2348 0.8436 3188387 PK04_103310 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P15 compound treatment 1.04152489E8 7650000.0 0.66 9.8211664E7 2620000.0 0.23 0.6289 0.8997 3188388 PK04_103311 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P16 compound treatment 9.7898452E7 1390000.0 0.12 9.3581837E7 -2010000.0 -0.18 -0.0396 -0.1853 3070122 PK04_103312 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P17 compound treatment 9.9269599E7 2760000.0 0.24 9.4808866E7 -787000.0 -0.07 0.1201 0.4833 3188389 PK04_103313 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P18 compound treatment 9.6208005E7 -297000.0 -0.03 9.1876491E7 -3720000.0 -0.33 -0.2483 -0.7605 3188390 PK04_103314 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P19 compound treatment 1.0089449E8 4390000.0 0.38 9.6172992E7 577000.0 0.05 0.3038 0.7942 3070123 PK04_103315 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P20 compound treatment 1.03717543E8 7210000.0 0.62 1.00895224E8 5300000.0 0.46 0.7684 0.9894 3188503 PK04_103316 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P21 compound treatment 1.04069872E8 7560000.0 0.65 1.08521383E8 1.29E7 1.13 1.2619 0.966 3188504 PK04_103317 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P22 compound treatment 1.04179946E8 7670000.0 0.66 1.02093754E8 6500000.0 0.57 0.8708 0.9971 3070124 PK04_103318 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P23 compound treatment 9.5508607E7 -996000.0 -0.09 9.9789486E7 4190000.0 0.37 0.1986 0.527 3188505 PK04_103319 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2103 P24 compound treatment 8.0329102E7 -1.62E7 -1.4 7.8207275E7 -1.74E7 -1.52 -2.064 -0.9991 3188506 PK04_103320 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A01 compound treatment 1.12481081E8 1.43E7 1.23 1.04981334E8 8050000.0 0.7 1.3707 0.9647 3220649 PK04_107001 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A02 compound treatment 8.856818E7 -9630000.0 -0.83 1.02026552E8 5100000.0 0.45 -0.2726 -0.2888 3188507 PK04_107002 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A03 compound treatment 1.05090571E8 6890000.0 0.6 9.7370272E7 441000.0 0.04 0.4484 0.7514 3220651 PK04_107003 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A04 compound treatment 1.07674028E8 9480000.0 0.82 9.40488E7 -2880000.0 -0.25 0.4006 0.4677 3070126 PK04_107004 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A05 compound treatment 1.01015876E8 2820000.0 0.24 1.01660482E8 4730000.0 0.41 0.465 0.968 3220653 PK04_107005 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A06 compound treatment 9.8138137E7 -58600.0 -0.01 1.0386378E8 6930000.0 0.61 0.4256 0.7012 3070127 PK04_107006 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A07 compound treatment 1.00860379E8 2660000.0 0.23 9.7938619E7 1010000.0 0.09 0.2252 0.9136 3220655 PK04_107007 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A08 compound treatment 1.04474873E8 6280000.0 0.54 9.1469438E7 -5460000.0 -0.48 0.0456 0.0631 3070128 PK04_107008 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A09 compound treatment 9.84457E7 249000.0 0.02 9.6955201E7 26400.0 0.0 0.0168 0.7785 3220657 PK04_107009 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A10 compound treatment 9.6141877E7 -2050000.0 -0.18 1.00195392E8 3270000.0 0.29 0.0766 0.2278 3070129 PK04_107010 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A11 compound treatment 9.9295512E7 1100000.0 0.09 9.3730917E7 -3200000.0 -0.28 -0.1308 -0.4426 3220659 PK04_107011 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A12 compound treatment 1.06219704E8 8020000.0 0.69 9.1101923E7 -5830000.0 -0.51 0.1294 0.1504 3188513 PK04_107012 CCCCCCc1nc(CCCc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)cc4CO[Si](C(C)C)(C(C)C)c41 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A13 mock treatment 9.7359018E7 -838000.0 -0.07 9.5245177E7 -1680000.0 -0.15 -0.1554 -0.9464 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A14 mock treatment 8.7455053E7 -1.07E7 -0.93 9.3296701E7 -3630000.0 -0.32 -0.8808 -0.8981 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A15 compound treatment 1.00332385E8 2140000.0 0.18 8.9245197E7 -7680000.0 -0.67 -0.3451 -0.4949 3220661 PK04_107013 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A16 compound treatment 7.9600739E7 -1.86E7 -1.61 6.9389683E7 -2.75E7 -2.41 -2.84 -0.9805 3188514 PK04_107014 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A17 compound treatment 9.8437205E7 240000.0 0.02 9.9491199E7 2560000.0 0.22 0.1733 0.7693 3220663 PK04_107015 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3ccccc3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A18 compound treatment 1.03920531E8 5720000.0 0.49 1.05805766E8 8880000.0 0.78 0.8989 0.9762 3070178 PK04_107016 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A19 compound treatment 1.04901501E8 6700000.0 0.58 8.9443854E7 -7480000.0 -0.66 -0.0537 -0.0614 3220665 PK04_107017 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A20 compound treatment 1.13667974E8 1.55E7 1.34 1.11715429E8 1.48E7 1.29 1.86 0.9999 3070179 PK04_107018 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A21 compound treatment 1.02615204E8 4420000.0 0.38 1.03548511E8 6620000.0 0.58 0.6795 0.9795 3220667 PK04_107019 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A22 compound treatment 9.5512678E7 -2680000.0 -0.23 1.04876962E8 7950000.0 0.7 0.3279 0.4473 3070180 PK04_107020 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A23 compound treatment 1.05344085E8 7150000.0 0.62 9.3973317E7 -2960000.0 -0.26 0.2536 0.3789 3220669 PK04_107021 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 A24 compound treatment 1.11921917E8 1.37E7 1.19 1.0717439E8 1.02E7 0.9 1.4723 0.9905 3070181 PK04_107022 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B01 compound treatment 1.10173614E8 1.2E7 1.03 1.02560066E8 5630000.0 0.49 1.08 0.9425 3188518 PK04_107023 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B02 compound treatment 1.05825211E8 7630000.0 0.66 9.071482E7 -6210000.0 -0.54 0.0814 0.0952 3188519 PK04_107024 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B03 compound treatment 1.05615992E8 7420000.0 0.64 9.9272386E7 2340000.0 0.21 0.5982 0.889 3070182 PK04_107025 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B04 compound treatment 9.2596387E7 -5600000.0 -0.48 9.5734871E7 -1190000.0 -0.1 -0.4159 -0.8405 3188520 PK04_107026 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B05 compound treatment 1.00157649E8 1960000.0 0.17 9.6478067E7 -451000.0 -0.04 0.0919 0.5283 3188521 PK04_107027 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B06 compound treatment 1.02169197E8 3970000.0 0.34 8.8307349E7 -8620000.0 -0.75 -0.2909 -0.351 3070183 PK04_107028 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B07 compound treatment 1.02401456E8 4200000.0 0.36 9.7163746E7 235000.0 0.02 0.2713 0.7459 3188640 PK04_107029 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B08 compound treatment 8.9249167E7 -8950000.0 -0.77 9.1798805E7 -5130000.0 -0.45 -0.8639 -0.9666 3188641 PK04_107030 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B09 compound treatment 9.8086938E7 -110000.0 -0.01 9.5960942E7 -968000.0 -0.08 -0.0666 -0.7814 3070184 PK04_107031 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B10 compound treatment 9.5735336E7 -2460000.0 -0.21 8.1527671E7 -1.54E7 -1.35 -1.1034 -0.8086 3188642 PK04_107032 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B11 compound treatment 9.9703719E7 1510000.0 0.13 9.4960909E7 -1970000.0 -0.17 -0.0297 -0.1378 3070185 PK04_107033 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B12 compound treatment 8.399409E7 -1.42E7 -1.23 9.2087542E7 -4840000.0 -0.42 -1.167 -0.8992 3188643 PK04_107034 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B13 mock treatment 9.7546227E7 -650000.0 -0.06 9.6336771E7 -592000.0 -0.05 -0.0764 -0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B14 mock treatment 9.3276446E7 -4920000.0 -0.42 8.1481415E7 -1.54E7 -1.35 -1.2565 -0.8866 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B15 compound treatment 9.963944E7 1440000.0 0.12 9.4005604E7 -2920000.0 -0.26 -0.0928 -0.3261 3188644 PK04_107035 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B16 compound treatment 8.9446757E7 -8750000.0 -0.76 9.617336E7 -755000.0 -0.07 -0.5812 -0.766 3070186 PK04_107036 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B17 compound treatment 1.02257685E8 4060000.0 0.35 1.00992081E8 4060000.0 0.36 0.4995 1.0 3188645 PK04_107037 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B18 compound treatment 9.8864793E7 668000.0 0.06 8.9634414E7 -7290000.0 -0.64 -0.4106 -0.6406 3188646 PK04_107038 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B19 compound treatment 1.02756204E8 4560000.0 0.39 1.00064193E8 3140000.0 0.27 0.4725 0.9844 3070187 PK04_107039 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B20 compound treatment 8.8305558E7 -9890000.0 -0.85 1.00766645E8 3840000.0 0.34 -0.3666 -0.3994 3188647 PK04_107040 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B21 compound treatment 1.07707929E8 9510000.0 0.82 1.04556139E8 7630000.0 0.67 1.0529 0.9947 3188648 PK04_107041 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B22 compound treatment 1.05959831E8 7760000.0 0.67 9.4969601E7 -1960000.0 -0.17 0.3529 0.5099 3070188 PK04_107042 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B23 compound treatment 1.00388189E8 2190000.0 0.19 1.08403256E8 1.15E7 1.0 0.8439 0.8258 3188649 PK04_107043 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 B24 compound treatment 1.08192008E8 1.0E7 0.86 1.04639232E8 7710000.0 0.67 1.0876 0.9926 3188650 PK04_107044 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C01 compound treatment 1.00289413E8 2090000.0 0.18 1.04684208E8 7760000.0 0.68 0.6077 0.8653 3414054 PK04_107045 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C02 compound treatment 1.07913603E8 9720000.0 0.84 9.6247452E7 -681000.0 -0.06 0.5513 0.6552 3188651 PK04_107046 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C03 compound treatment 1.01675818E8 3480000.0 0.3 8.7643532E7 -9290000.0 -0.81 -0.3621 -0.418 3414055 PK04_107047 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C04 compound treatment 9.9272855E7 1080000.0 0.09 9.7172315E7 243000.0 0.02 0.0808 0.8472 3070235 PK04_107048 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C05 compound treatment 8.7663263E7 -1.05E7 -0.91 9.6655663E7 -273000.0 -0.02 -0.6602 -0.7254 3414056 PK04_107049 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C06 compound treatment 1.02158448E8 3960000.0 0.34 9.4326355E7 -2600000.0 -0.23 0.0809 0.1968 3070236 PK04_107050 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C07 compound treatment 9.9578736E7 1380000.0 0.12 9.6102611E7 -826000.0 -0.07 0.0333 0.2384 3414057 PK04_107051 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C08 compound treatment 9.5533154E7 -2660000.0 -0.23 9.7762677E7 834000.0 0.07 -0.1111 -0.4602 3188655 PK04_107052 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C09 compound treatment 9.1825469E7 -6370000.0 -0.55 9.2580913E7 -4350000.0 -0.38 -0.6582 -0.9838 3220705 PK04_107053 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C10 compound treatment 9.6892371E7 -1300000.0 -0.11 8.6108985E7 -1.08E7 -0.95 -0.7492 -0.7857 3188656 PK04_107054 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C11 mock treatment 9.4365201E7 -3830000.0 -0.33 9.4936415E7 -1990000.0 -0.17 -0.3573 -0.9552 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C12 mock treatment 8.592459E7 -1.23E7 -1.06 9.1299951E7 -5630000.0 -0.49 -1.0979 -0.9393 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C13 compound treatment 9.3174363E7 -5020000.0 -0.43 9.072773E7 -6200000.0 -0.54 -0.6905 -0.9938 3220708 PK04_107055 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C14 compound treatment 9.2245514E7 -5950000.0 -0.51 9.3393573E7 -3540000.0 -0.31 -0.5822 -0.9705 3188772 PK04_107056 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C15 mock treatment 8.805078E7 -1.01E7 -0.88 9.5847114E7 -1080000.0 -0.09 -0.6866 -0.779 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C16 mock treatment 8.5001379E7 -1.32E7 -1.14 9.6454003E7 -475000.0 -0.04 -0.8353 -0.7324 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C17 compound treatment 9.2764002E7 -5430000.0 -0.47 8.4086803E7 -1.28E7 -1.12 -1.1265 -0.925 3220711 PK04_107057 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C18 compound treatment 1.04380177E8 6180000.0 0.53 1.03705364E8 6780000.0 0.59 0.797 0.9986 3070242 PK04_107058 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C19 compound treatment 9.998011E7 1780000.0 0.15 1.03327812E8 6400000.0 0.56 0.5049 0.8693 3220713 PK04_107059 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C20 compound treatment 9.6891756E7 -1300000.0 -0.11 1.04940933E8 8010000.0 0.7 0.4161 0.5859 3070245 PK04_107060 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C21 compound treatment 1.06676576E8 8480000.0 0.73 9.5638232E7 -1290000.0 -0.11 0.438 0.5911 3220715 PK04_107061 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C22 compound treatment 1.05997914E8 7800000.0 0.67 1.05808909E8 8880000.0 0.78 1.026 0.9975 3070527 PK04_107062 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C23 compound treatment 1.05326996E8 7130000.0 0.62 1.05582038E8 8650000.0 0.76 0.971 0.9947 3220717 PK04_107063 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 C24 compound treatment 1.05843292E8 7650000.0 0.66 1.05082577E8 8150000.0 0.71 0.9716 0.9993 3070530 PK04_107064 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D01 compound treatment 9.5819473E7 -2380000.0 -0.21 1.06306216E8 9380000.0 0.82 0.4351 0.5143 3188777 PK04_107065 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D02 compound treatment 1.03916485E8 5720000.0 0.49 1.01308855E8 4380000.0 0.38 0.6204 0.9921 3188778 PK04_107066 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D03 compound treatment 1.07631602E8 9430000.0 0.81 9.5765838E7 -1160000.0 -0.1 0.5043 0.614 3070575 PK04_107067 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D04 compound treatment 1.00594114E8 2400000.0 0.21 8.7937304E7 -8990000.0 -0.79 -0.41 -0.5039 3188779 PK04_107068 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D05 compound treatment 9.4086119E7 -4110000.0 -0.36 9.4282082E7 -2650000.0 -0.23 -0.4148 -0.9786 3188780 PK04_107069 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D06 compound treatment 9.6147352E7 -2050000.0 -0.18 9.267624E7 -4250000.0 -0.37 -0.3883 -0.9423 3070579 PK04_107070 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D07 compound treatment 1.0422987E8 6030000.0 0.52 9.9883196E7 2950000.0 0.26 0.5513 0.9477 3188781 PK04_107071 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D08 compound treatment 9.4975534E7 -3220000.0 -0.28 8.3951362E7 -1.3E7 -1.14 -0.9998 -0.855 3188782 PK04_107072 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D09 compound treatment 8.7880127E7 -1.03E7 -0.89 9.7059112E7 130000.0 0.01 -0.622 -0.698 3188783 PK04_107073 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D10 compound treatment 9.1229325E7 -6970000.0 -0.6 9.4563449E7 -2370000.0 -0.21 -0.5719 -0.8987 3070632 PK04_107074 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D11 mock treatment 9.7924512E7 -272000.0 -0.02 9.8647993E7 1720000.0 0.15 0.0898 0.5895 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D12 mock treatment 9.3139576E7 -5060000.0 -0.44 8.129513E7 -1.56E7 -1.37 -1.2763 -0.8887 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D13 compound treatment 9.0265031E7 -7930000.0 -0.69 9.6091018E7 -838000.0 -0.07 -0.5363 -0.7783 3188784 PK04_107075 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D14 compound treatment 8.7728407E7 -1.05E7 -0.9 9.1636366E7 -5290000.0 -0.46 -0.9669 -0.9517 3188785 PK04_107076 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D15 mock treatment 9.6525871E7 -1670000.0 -0.14 9.7375657E7 447000.0 0.04 -0.0744 -0.4976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D16 mock treatment 9.5332322E7 -2860000.0 -0.25 8.8378747E7 -8550000.0 -0.75 -0.7041 -0.8933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D17 compound treatment 8.7652611E7 -1.05E7 -0.91 9.8588951E7 1660000.0 0.15 -0.5412 -0.5869 3070637 PK04_107077 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D18 compound treatment 9.5139859E7 -3060000.0 -0.26 9.7622897E7 694000.0 0.06 -0.1437 -0.5306 3188786 PK04_107078 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D19 compound treatment 1.0544637E8 7250000.0 0.63 9.8265258E7 1340000.0 0.12 0.5255 0.8249 3188787 PK04_107079 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D20 compound treatment 9.7920451E7 -276000.0 -0.02 9.7716372E7 788000.0 0.07 0.0319 0.4369 3070641 PK04_107080 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D21 compound treatment 9.9303549E7 1110000.0 0.1 1.09303974E8 1.24E7 1.08 0.8334 0.7665 3188905 PK04_107081 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D22 compound treatment 9.9759083E7 1560000.0 0.13 1.01764492E8 4840000.0 0.42 0.3947 0.8885 3188906 PK04_107082 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D23 compound treatment 1.10556312E8 1.24E7 1.07 1.05554562E8 8630000.0 0.75 1.2887 0.9856 3070684 PK04_107083 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 D24 compound treatment 1.12652533E8 1.45E7 1.25 1.12222128E8 1.53E7 1.34 1.8293 0.9994 3188907 PK04_107084 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E01 mock treatment 1.07830214E8 9630000.0 0.83 9.939654E7 2470000.0 0.22 0.7411 0.8621 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E02 mock treatment 1.08064022E8 9870000.0 0.85 9.9149133E7 2220000.0 0.19 0.74 0.8466 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E03 compound treatment 1.04909917E8 6710000.0 0.58 9.798235E7 1050000.0 0.09 0.4752 0.8094 3220739 PK04_107085 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E04 compound treatment 1.01591297E8 3390000.0 0.29 9.7969736E7 1040000.0 0.09 0.2717 0.8851 3070690 PK04_107086 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E05 compound treatment 1.00807477E8 2610000.0 0.23 9.7916949E7 988000.0 0.09 0.2206 0.9134 3220741 PK04_107087 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E06 compound treatment 9.7239156E7 -958000.0 -0.08 9.5602994E7 -1330000.0 -0.12 -0.1405 -0.9862 3070694 PK04_107088 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E07 compound treatment 9.8326739E7 130000.0 0.01 9.5695886E7 -1230000.0 -0.11 -0.0684 -0.6301 3220743 PK04_107089 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E08 compound treatment 9.6725711E7 -1470000.0 -0.13 9.6771335E7 -158000.0 -0.01 -0.0996 -0.7792 3188910 PK04_107090 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E09 mock treatment 9.2404739E7 -5790000.0 -0.5 9.3397839E7 -3530000.0 -0.31 -0.5723 -0.9732 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E10 mock treatment 9.0930388E7 -7270000.0 -0.63 9.1946057E7 -4980000.0 -0.44 -0.7521 -0.9842 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E11 compound treatment 9.2075534E7 -6120000.0 -0.53 9.1871977E7 -5060000.0 -0.44 -0.6868 -0.9961 3188911 PK04_107091 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E12 compound treatment 9.232077E7 -5880000.0 -0.51 9.6403767E7 -525000.0 -0.05 -0.3914 -0.768 3070742 PK04_107092 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E13 compound treatment 8.7692683E7 -1.05E7 -0.91 9.4645853E7 -2280000.0 -0.2 -0.7828 -0.8426 3188912 PK04_107093 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E14 compound treatment 9.1414815E7 -6780000.0 -0.59 9.5015751E7 -1910000.0 -0.17 -0.5326 -0.8742 3070746 PK04_107094 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E15 compound treatment 9.3782013E7 -4410000.0 -0.38 9.6656317E7 -273000.0 -0.02 -0.2865 -0.7499 3188913 PK04_107095 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E16 compound treatment 9.2091061E7 -6110000.0 -0.53 9.8271065E7 1340000.0 0.12 -0.2898 -0.5365 3070750 PK04_107096 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E17 mock treatment 8.3119127E7 -1.51E7 -1.3 1.05257092E8 8330000.0 0.73 -0.4055 -0.2717 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E18 mock treatment 8.2599162E7 -1.56E7 -1.35 1.06657988E8 9730000.0 0.85 -0.3505 -0.2199 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E19 compound treatment 1.00706513E8 2510000.0 0.22 1.01725094E8 4800000.0 0.42 0.4501 0.9527 3220747 PK04_107097 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E20 compound treatment 1.04488451E8 6290000.0 0.54 1.07357268E8 1.04E7 0.91 1.0296 0.9693 3188915 PK04_107098 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E21 compound treatment 1.0137238E8 3180000.0 0.27 1.02108367E8 5180000.0 0.45 0.5145 0.971 3220749 PK04_107099 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E22 compound treatment 1.0262631E8 4430000.0 0.38 1.03838601E8 6910000.0 0.6 0.6981 0.9756 3070803 PK04_107100 CC(C)[Si](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)(C#Cc3ccc(Oc4ccccc4)cc3)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E23 compound treatment 1.05963953E8 7770000.0 0.67 1.04686863E8 7760000.0 0.68 0.9545 1.0 3220751 PK04_107101 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 E24 compound treatment 1.08058918E8 9860000.0 0.85 1.09056836E8 1.21E7 1.06 1.3529 0.9941 3070808 PK04_107102 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F01 mock treatment 1.10534087E8 1.23E7 1.07 9.6021062E7 -908000.0 -0.08 0.6973 0.6526 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F02 mock treatment 1.02957656E8 4760000.0 0.41 9.7218116E7 289000.0 0.03 0.3087 0.7492 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F03 compound treatment 1.00982094E8 2790000.0 0.24 9.924911E7 2320000.0 0.2 0.3137 0.9964 3188918 PK04_107103 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F04 compound treatment 9.8038922E7 -158000.0 -0.01 9.5251676E7 -1680000.0 -0.15 -0.1134 -0.7695 3188919 PK04_107104 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F05 compound treatment 9.5679326E7 -2520000.0 -0.22 9.7553353E7 625000.0 0.05 -0.1151 -0.5134 3188920 PK04_107105 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F06 compound treatment 9.7620854E7 -576000.0 -0.05 9.0685738E7 -6240000.0 -0.55 -0.4215 -0.7683 3188921 PK04_107106 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F07 compound treatment 1.02876414E8 4680000.0 0.4 9.7602028E7 673000.0 0.06 0.3275 0.8017 3070852 PK04_107107 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F08 compound treatment 9.3924898E7 -4270000.0 -0.37 9.3338503E7 -3590000.0 -0.31 -0.4831 -0.9968 3188922 PK04_107108 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F09 mock treatment 9.8385136E7 188000.0 0.02 9.4437492E7 -2490000.0 -0.22 -0.1427 -0.6525 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F10 mock treatment 9.1942757E7 -6250000.0 -0.54 9.4945583E7 -1980000.0 -0.17 -0.5047 -0.8895 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F11 compound treatment 9.7492133E7 -705000.0 -0.06 9.8457879E7 1530000.0 0.13 0.0516 0.3509 3189029 PK04_107109 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F12 compound treatment 8.3953797E7 -1.42E7 -1.23 9.4717017E7 -2210000.0 -0.19 -1.0068 -0.8084 3070859 PK04_107110 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F13 compound treatment 9.4681581E7 -3520000.0 -0.3 9.8255286E7 1330000.0 0.12 -0.1326 -0.4079 3189030 PK04_107111 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F14 compound treatment 9.1149758E7 -7050000.0 -0.61 9.6379655E7 -549000.0 -0.05 -0.4644 -0.7606 3189031 PK04_107112 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F15 compound treatment 9.6104146E7 -2090000.0 -0.18 1.02193186E8 5260000.0 0.46 0.198 0.4 3070862 PK04_107113 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F16 compound treatment 9.4431737E7 -3760000.0 -0.33 9.6099048E7 -830000.0 -0.07 -0.2813 -0.8442 3189032 PK04_107114 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F17 mock treatment 7.8078481E7 -2.01E7 -1.74 1.05361249E8 8430000.0 0.74 -0.7069 -0.3744 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F18 mock treatment 7.3370341E7 -2.48E7 -2.14 1.04956991E8 8030000.0 0.7 -1.0194 -0.4518 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F19 compound treatment 1.0023467E8 2040000.0 0.18 1.03773823E8 6840000.0 0.6 0.5481 0.8778 3189033 PK04_107115 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F20 compound treatment 9.8328528E7 132000.0 0.01 1.0314224E8 6210000.0 0.54 0.3926 0.7218 3070022 PK04_107116 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F21 compound treatment 1.04334657E8 6140000.0 0.53 1.06102532E8 9170000.0 0.8 0.9426 0.9797 3189034 PK04_107117 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F22 compound treatment 1.03367445E8 5170000.0 0.45 1.04695786E8 7770000.0 0.68 0.7965 0.9792 3189035 PK04_107118 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F23 compound treatment 1.06461244E8 8260000.0 0.71 1.09472349E8 1.25E7 1.1 1.281 0.9783 3070031 PK04_107119 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 F24 compound treatment 1.00976791E8 2780000.0 0.24 1.06837365E8 9910000.0 0.87 0.783 0.8702 3189036 PK04_107120 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G01 compound treatment 1.13018751E8 1.48E7 1.28 1.03445206E8 6520000.0 0.57 1.3085 0.9337 3220772 PK04_107121 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G02 compound treatment 1.10021326E8 1.18E7 1.02 9.6930096E7 1260.0 0.0 0.7223 0.7072 3070078 PK04_107122 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G03 mock treatment 1.02822985E8 4630000.0 0.4 9.5701678E7 -1230000.0 -0.11 0.2066 0.4993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G04 mock treatment 9.9004648E7 808000.0 0.07 9.3793687E7 -3140000.0 -0.27 -0.1447 -0.511 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G05 compound treatment 1.0179967E8 3600000.0 0.31 9.4326636E7 -2600000.0 -0.23 0.059 0.153 3220775 PK04_107123 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G06 compound treatment 7.9146926E7 -1.9E7 -1.65 8.3483155E7 -1.34E7 -1.18 -1.9955 -0.9865 3070081 PK04_107124 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G07 compound treatment 1.00238623E8 2040000.0 0.18 9.5372409E7 -1560000.0 -0.14 0.0284 0.1274 3189039 PK04_107125 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G08 compound treatment 9.7244634E7 -952000.0 -0.08 9.838477E7 1460000.0 0.13 0.032 0.2107 3189040 PK04_107126 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G09 compound treatment 9.3243818E7 -4950000.0 -0.43 9.4815591E7 -2110000.0 -0.18 -0.4333 -0.9296 3070086 PK04_107127 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G10 compound treatment 1.01030927E8 2830000.0 0.24 9.6580627E7 -348000.0 -0.03 0.1515 0.6143 3189041 PK04_107128 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G11 compound treatment 9.4096529E7 -4100000.0 -0.35 9.4968056E7 -1960000.0 -0.17 -0.3718 -0.9447 3070089 PK04_107129 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G12 compound treatment 9.5876618E7 -2320000.0 -0.2 9.4788591E7 -2140000.0 -0.19 -0.2741 -0.9994 3189042 PK04_107130 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G13 compound treatment 9.1094208E7 -7100000.0 -0.61 9.3844832E7 -3080000.0 -0.27 -0.6246 -0.932 3070134 PK04_107131 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G14 compound treatment 9.0303377E7 -7890000.0 -0.68 9.7002613E7 73800.0 0.01 -0.4775 -0.7004 3070137 PK04_107132 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G15 compound treatment 9.6464466E7 -1730000.0 -0.15 9.6121137E7 -808000.0 -0.07 -0.1558 -0.9414 3189043 PK04_107133 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G16 compound treatment 9.7528868E7 -668000.0 -0.06 9.9473396E7 2540000.0 0.22 0.1167 0.5072 3189044 PK04_107134 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G17 compound treatment 9.3216276E7 -4980000.0 -0.43 9.715362E7 225000.0 0.02 -0.2903 -0.6741 3070143 PK04_107135 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G18 compound treatment 1.02706086E8 4510000.0 0.39 1.03083856E8 6160000.0 0.54 0.6563 0.9873 3189045 PK04_107136 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G19 mock treatment 1.02204716E8 4010000.0 0.35 1.02761489E8 5830000.0 0.51 0.6057 0.9821 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G20 mock treatment 1.0123322E8 3040000.0 0.26 1.00622285E8 3690000.0 0.32 0.414 0.9946 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G21 compound treatment 9.9381802E7 1190000.0 0.1 1.0097259E8 4040000.0 0.35 0.3226 0.8757 3070191 PK04_107137 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G22 compound treatment 8.6002793E7 -1.22E7 -1.05 8.2385871E7 -1.45E7 -1.27 -1.6447 -0.9956 3189046 PK04_107138 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G23 compound treatment 1.07582211E8 9390000.0 0.81 1.05569344E8 8640000.0 0.76 1.1079 0.9994 3070196 PK04_107139 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 G24 compound treatment 1.13684682E8 1.55E7 1.34 1.12832704E8 1.59E7 1.39 1.9301 0.9998 3189047 PK04_107140 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H01 compound treatment 1.14926307E8 1.67E7 1.44 1.06262692E8 9330000.0 0.82 1.5994 0.9635 3189157 PK04_107141 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H02 compound treatment 1.05356075E8 7160000.0 0.62 9.2419137E7 -4510000.0 -0.39 0.1582 0.2156 3189158 PK04_107142 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H03 mock treatment 1.05306622E8 7110000.0 0.61 9.9359736E7 2430000.0 0.21 0.5847 0.8996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H04 mock treatment 9.9528242E7 1330000.0 0.12 9.3583049E7 -3350000.0 -0.29 -0.1257 -0.3997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H05 compound treatment 1.00484811E8 2290000.0 0.2 9.7298962E7 370000.0 0.03 0.1626 0.8122 3070201 PK04_107143 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H06 compound treatment 9.7590813E7 -606000.0 -0.05 9.3327017E7 -3600000.0 -0.32 -0.2599 -0.8134 3189159 PK04_107144 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H07 compound treatment 1.03087918E8 4890000.0 0.42 9.7443719E7 515000.0 0.05 0.3306 0.7781 3071172 PK04_107145 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H08 compound treatment 9.3079497E7 -5120000.0 -0.44 9.4615741E7 -2310000.0 -0.2 -0.4557 -0.9373 3071173 PK04_107146 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H09 compound treatment 1.04600799E8 6400000.0 0.55 1.0066991E8 3740000.0 0.33 0.6226 0.9687 3071174 PK04_107147 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H10 compound treatment 9.5856561E7 -2340000.0 -0.2 9.3092086E7 -3840000.0 -0.34 -0.3804 -0.9705 3189160 PK04_107148 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H11 compound treatment 9.9188906E7 992000.0 0.09 9.7828589E7 900000.0 0.08 0.1163 0.9991 3189161 PK04_107149 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H12 compound treatment 9.6510364E7 -1690000.0 -0.15 9.2178477E7 -4750000.0 -0.42 -0.397 -0.9011 3071175 PK04_107150 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H13 compound treatment 9.9555286E7 1360000.0 0.12 9.7331788E7 403000.0 0.04 0.1079 0.8807 3189162 PK04_107151 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H14 compound treatment 9.0405285E7 -7790000.0 -0.67 9.4812971E7 -2120000.0 -0.19 -0.6068 -0.8694 3189163 PK04_107152 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H15 compound treatment 9.9833882E7 1640000.0 0.14 9.7726639E7 798000.0 0.07 0.1494 0.9471 3071176 PK04_107153 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H16 compound treatment 8.6863695E7 -1.13E7 -0.98 9.3179138E7 -3750000.0 -0.33 -0.9242 -0.8952 3189164 PK04_107154 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H17 compound treatment 1.02469222E8 4270000.0 0.37 1.04026685E8 7100000.0 0.62 0.7002 0.9691 3189165 PK04_107155 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H18 compound treatment 9.7804734E7 -392000.0 -0.03 1.00146455E8 3220000.0 0.28 0.1752 0.6176 3071177 PK04_107156 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H19 mock treatment 1.02488981E8 4290000.0 0.37 1.04294128E8 7370000.0 0.64 0.7179 0.9655 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H20 mock treatment 9.9191323E7 995000.0 0.09 9.9329199E7 2400000.0 0.21 0.2093 0.9221 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H21 compound treatment 1.07926429E8 9730000.0 0.84 1.0831039E8 1.14E7 1.0 1.2986 0.9964 3189166 PK04_107157 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H22 compound treatment 1.0301726E8 4820000.0 0.42 1.02585947E8 5660000.0 0.5 0.6445 0.9963 3189167 PK04_107158 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H23 compound treatment 1.09594468E8 1.14E7 0.98 1.08255389E8 1.13E7 0.99 1.397 1.0 3071178 PK04_107159 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 H24 compound treatment 1.06124801E8 7930000.0 0.68 1.08826084E8 1.19E7 1.04 1.2205 0.9793 3189168 PK04_107160 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I01 compound treatment 1.10729854E8 1.25E7 1.08 1.00373328E8 3440000.0 0.3 0.9786 0.8709 3071179 PK04_107161 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I02 compound treatment 1.04310381E8 6110000.0 0.53 9.7685344E7 757000.0 0.07 0.4202 0.7896 3189169 PK04_107162 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I03 compound treatment 1.02373394E8 4180000.0 0.36 9.8705656E7 1780000.0 0.16 0.365 0.9293 3071180 PK04_107163 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I04 compound treatment 1.01102995E8 2910000.0 0.25 9.8471304E7 1540000.0 0.13 0.273 0.9577 3189170 PK04_107164 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I05 mock treatment 1.01992188E8 3800000.0 0.33 9.8801929E7 1870000.0 0.16 0.3477 0.9487 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I06 mock treatment 9.7529844E7 -667000.0 -0.06 9.5972041E7 -957000.0 -0.08 -0.0999 -0.9833 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I07 compound treatment 9.3026066E7 -5170000.0 -0.45 9.4041888E7 -2890000.0 -0.25 -0.4945 -0.9636 3071181 PK04_107165 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I08 compound treatment 1.01741081E8 3540000.0 0.31 1.04033021E8 7100000.0 0.62 0.6561 0.9467 3189171 PK04_107166 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I09 compound treatment 8.9067845E7 -9130000.0 -0.79 9.441799E7 -2510000.0 -0.22 -0.7129 -0.871 3189172 PK04_107167 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I10 compound treatment 9.5462947E7 -2730000.0 -0.24 9.6628286E7 -301000.0 -0.03 -0.1856 -0.781 3071182 PK04_107168 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I11 compound treatment 9.4743949E7 -3450000.0 -0.3 9.6510606E7 -418000.0 -0.04 -0.2368 -0.788 3189173 PK04_107169 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I12 compound treatment 9.1044395E7 -7150000.0 -0.62 9.2661568E7 -4270000.0 -0.37 -0.7009 -0.9709 3189286 PK04_107170 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I13 compound treatment 9.8089772E7 -107000.0 -0.01 1.00740052E8 3810000.0 0.33 0.2293 0.6873 3071183 PK04_107171 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I14 compound treatment 9.7903351E7 -293000.0 -0.03 9.939173E7 2460000.0 0.22 0.1345 0.6197 3189287 PK04_107172 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I15 compound treatment 9.7869731E7 -327000.0 -0.03 9.9051691E7 2120000.0 0.19 0.1114 0.5928 3071184 PK04_107173 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I16 compound treatment 1.038014E8 5600000.0 0.48 1.02615017E8 5690000.0 0.5 0.6942 0.9999 3189288 PK04_107174 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I17 compound treatment 9.8795814E7 599000.0 0.05 1.01270903E8 4340000.0 0.38 0.3053 0.796 3071185 PK04_107175 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I18 compound treatment 9.3732454E7 -4460000.0 -0.39 9.3435699E7 -3490000.0 -0.31 -0.4888 -0.9934 3189289 PK04_107176 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I19 compound treatment 1.00362384E8 2170000.0 0.19 1.03289823E8 6360000.0 0.56 0.5259 0.8955 3071186 PK04_107177 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I20 compound treatment 1.0370172E8 5500000.0 0.48 1.06127123E8 9200000.0 0.81 0.9054 0.9684 3189171 PK04_107178 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I21 mock treatment 1.02988979E8 4790000.0 0.41 1.04454324E8 7530000.0 0.66 0.7584 0.9749 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I22 mock treatment 1.02569504E8 4370000.0 0.38 1.03449829E8 6520000.0 0.57 0.6706 0.9799 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I23 compound treatment 8.4755848E7 -1.34E7 -1.16 9.1013119E7 -5920000.0 -0.52 -1.187 -0.9338 3189290 PK04_107179 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 I24 compound treatment 8.488298E7 -1.33E7 -1.15 9.7468742E7 540000.0 0.05 -0.7797 -0.6775 3071182 PK04_107180 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J01 compound treatment 1.13437541E8 1.52E7 1.32 1.0625303E8 9320000.0 0.82 1.5078 0.9736 3189291 PK04_107181 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J02 compound treatment 1.07149272E8 8950000.0 0.77 9.9752875E7 2820000.0 0.25 0.7215 0.8888 3071187 PK04_107182 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J03 compound treatment 1.080526E8 9860000.0 0.85 1.0028927E8 3360000.0 0.29 0.8099 0.8992 3189292 PK04_107183 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J04 compound treatment 9.8580435E7 384000.0 0.03 9.2924196E7 -4000000.0 -0.35 -0.2244 -0.6374 3189293 PK04_107184 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J05 mock treatment 1.03332541E8 5140000.0 0.44 9.8037993E7 1110000.0 0.1 0.3823 0.8419 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J06 mock treatment 9.4085811E7 -4110000.0 -0.36 9.1561559E7 -5370000.0 -0.47 -0.5832 -0.9905 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J07 compound treatment 1.03011533E8 4810000.0 0.42 1.0263819E8 5710000.0 0.5 0.6474 0.9958 3071188 PK04_107185 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J08 compound treatment 9.3984382E7 -4210000.0 -0.36 9.6367999E7 -561000.0 -0.05 -0.292 -0.7953 3189294 PK04_107186 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J09 compound treatment 1.01168529E8 2970000.0 0.26 9.7693253E7 764000.0 0.07 0.2288 0.8626 3189295 PK04_107187 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J10 compound treatment 9.6325885E7 -1870000.0 -0.16 9.4471289E7 -2460000.0 -0.22 -0.2663 -0.9901 3071189 PK04_107188 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J11 compound treatment 9.9930455E7 1730000.0 0.15 1.00292921E8 3360000.0 0.29 0.3141 0.9508 3189296 PK04_107189 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J12 compound treatment 9.4747361E7 -3450000.0 -0.3 9.4247285E7 -2680000.0 -0.23 -0.3766 -0.993 3189297 PK04_107190 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J13 compound treatment 9.9917423E7 1720000.0 0.15 1.00103277E8 3170000.0 0.28 0.3015 0.957 3071190 PK04_107191 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J14 compound treatment 9.3818172E7 -4380000.0 -0.38 9.6886144E7 -42700.0 0.0 -0.2701 -0.7141 3189298 PK04_107192 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J15 compound treatment 1.01517928E8 3320000.0 0.29 1.01953902E8 5030000.0 0.44 0.5138 0.9786 3071191 PK04_107193 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J16 compound treatment 9.5714498E7 -2480000.0 -0.21 9.552003E7 -1410000.0 -0.12 -0.2388 -0.9655 3189299 PK04_107194 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J17 compound treatment 1.02562593E8 4370000.0 0.38 1.04260427E8 7330000.0 0.64 0.7204 0.9679 3189300 PK04_107195 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J18 compound treatment 9.6300478E7 -1900000.0 -0.16 9.9290587E7 2360000.0 0.21 0.0303 0.1151 3071192 PK04_107196 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J19 compound treatment 1.01596007E8 3400000.0 0.29 1.05535827E8 8610000.0 0.75 0.7402 0.9156 3189301 PK04_107197 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J20 compound treatment 9.9759426E7 1560000.0 0.13 1.01825349E8 4900000.0 0.43 0.3985 0.8869 3189302 PK04_107198 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J21 mock treatment 1.03663801E8 5470000.0 0.47 1.05784005E8 8860000.0 0.77 0.8819 0.9718 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J22 mock treatment 9.8091966E7 -105000.0 -0.01 1.02436754E8 5510000.0 0.48 0.3345 0.6937 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J23 compound treatment 8.2731295E7 -1.55E7 -1.34 1.03823896E8 6900000.0 0.6 -0.5178 -0.3533 3071251 PK04_107199 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 J24 compound treatment 8.8308037E7 -9890000.0 -0.85 1.08150191E8 1.12E7 0.98 0.0905 0.0695 3189414 PK04_107200 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K01 compound treatment 1.1241605E8 1.42E7 1.23 1.07690426E8 1.08E7 0.94 1.5344 0.9914 3071252 PK04_107201 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K02 compound treatment 1.04922308E8 6730000.0 0.58 9.3869643E7 -3060000.0 -0.27 0.2214 0.3462 3189415 PK04_107202 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K03 compound treatment 1.05258562E8 7060000.0 0.61 1.01006763E8 4080000.0 0.36 0.6837 0.9674 3071253 PK04_107203 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K04 compound treatment 9.974188E7 1550000.0 0.13 1.03254929E8 6330000.0 0.55 0.4859 0.8531 3189416 PK04_107204 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K05 compound treatment 1.08153579E8 9960000.0 0.86 9.6925787E7 -3050.0 0.0 0.6079 0.7069 3189417 PK04_107205 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K06 compound treatment 9.4342407E7 -3850000.0 -0.33 9.0500067E7 -6430000.0 -0.56 -0.6332 -0.9686 3071254 PK04_107206 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K07 mock treatment 1.00450013E8 2250000.0 0.19 9.7894144E7 965000.0 0.08 0.1974 0.9302 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K08 mock treatment 9.3142809E7 -5050000.0 -0.44 9.362955E7 -3300000.0 -0.29 -0.5128 -0.9799 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K09 compound treatment 9.8966523E7 770000.0 0.07 9.7965556E7 1040000.0 0.09 0.1112 0.9883 3071255 PK04_107207 NC(=N)NCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K10 compound treatment 9.3101635E7 -5100000.0 -0.44 9.1749409E7 -5180000.0 -0.45 -0.6317 -0.9999 3189418 PK04_107208 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K11 compound treatment 9.7785053E7 -412000.0 -0.04 9.5160551E7 -1770000.0 -0.15 -0.1346 -0.8475 3189419 PK04_107209 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K12 compound treatment 8.8589111E7 -9610000.0 -0.83 9.5506691E7 -1420000.0 -0.12 -0.6748 -0.8042 3071256 PK04_107210 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K13 compound treatment 9.6903061E7 -1290000.0 -0.11 1.0527032E8 8340000.0 0.73 0.4372 0.592 3189420 PK04_107211 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K14 compound treatment 9.5260322E7 -2940000.0 -0.25 8.9916151E7 -7010000.0 -0.61 -0.6133 -0.9236 3071257 PK04_107212 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K15 mock treatment 9.6707254E7 -1490000.0 -0.13 9.2093926E7 -4830000.0 -0.42 -0.3902 -0.8822 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K16 mock treatment 1.01735305E8 3540000.0 0.31 8.3563926E7 -1.34E7 -1.17 -0.611 -0.5054 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K17 compound treatment 1.00314126E8 2120000.0 0.18 1.05211916E8 8280000.0 0.72 0.6419 0.8586 1035256 PK04_107213 C#CCNCc1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K18 compound treatment 1.00975323E8 2780000.0 0.24 1.0155701E8 4630000.0 0.41 0.4561 0.9688 3189421 PK04_107214 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K19 compound treatment 1.03742344E8 5550000.0 0.48 1.01683368E8 4750000.0 0.42 0.6329 0.9975 3071258 PK04_107215 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K20 compound treatment 8.8582686E7 -9610000.0 -0.83 9.5889934E7 -1040000.0 -0.09 -0.6515 -0.7799 3189422 PK04_107216 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K21 compound treatment 1.09507535E8 1.13E7 0.98 1.09422557E8 1.25E7 1.09 1.464 0.9984 3189423 PK04_107217 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K22 compound treatment 9.7137678E7 -1060000.0 -0.09 1.0024774E8 3320000.0 0.29 0.1407 0.4621 3071259 PK04_107218 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K23 mock treatment 1.06536736E8 8340000.0 0.72 1.10291117E8 1.34E7 1.17 1.3363 0.9729 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 K24 mock treatment 1.03713129E8 5520000.0 0.48 1.06538581E8 9610000.0 0.84 0.9316 0.9638 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L01 compound treatment 1.0959486E8 1.14E7 0.98 9.760384E7 675000.0 0.06 0.7379 0.7482 3189424 PK04_107219 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L02 compound treatment 1.00358639E8 2160000.0 0.19 9.558194E7 -1350000.0 -0.12 0.0487 0.2205 3189425 PK04_107220 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L03 compound treatment 1.08177394E8 9980000.0 0.86 9.8343404E7 1410000.0 0.12 0.6971 0.8004 3071260 PK04_107221 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L04 compound treatment 1.00549233E8 2350000.0 0.2 9.8460443E7 1530000.0 0.13 0.2385 0.9796 3189426 PK04_107222 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L05 compound treatment 1.00124543E8 1930000.0 0.17 9.9799272E7 2870000.0 0.25 0.2954 0.9801 3189427 PK04_107223 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L06 compound treatment 9.9268679E7 1070000.0 0.09 9.3029293E7 -3900000.0 -0.34 -0.1759 -0.4973 3071261 PK04_107224 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L07 mock treatment 1.00995202E8 2800000.0 0.24 1.00114057E8 3190000.0 0.28 0.368 0.9975 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L08 mock treatment 9.4934858E7 -3260000.0 -0.28 9.3981413E7 -2950000.0 -0.26 -0.3816 -0.999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L09 compound treatment 1.01662409E8 3470000.0 0.3 9.7749911E7 821000.0 0.07 0.2625 0.8526 3189428 PK04_107225 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L10 compound treatment 9.6683513E7 -1510000.0 -0.13 9.3894135E7 -3030000.0 -0.27 -0.2802 -0.9467 3189429 PK04_107226 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L11 compound treatment 9.2413794E7 -5780000.0 -0.5 1.02184698E8 5260000.0 0.46 -0.0279 -0.0411 3071262 PK04_107227 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L12 compound treatment 1.02397766E8 4200000.0 0.36 9.587455E7 -1050000.0 -0.09 0.1913 0.511 3189430 PK04_107228 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L13 compound treatment 9.557496E7 -2620000.0 -0.23 1.00766888E8 3840000.0 0.34 0.0774 0.191 3189431 PK04_107229 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L14 compound treatment 9.7123583E7 -1070000.0 -0.09 9.56417E7 -1290000.0 -0.11 -0.1452 -0.9953 3071263 PK04_107230 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L15 mock treatment 9.9036693E7 840000.0 0.07 9.2142499E7 -4790000.0 -0.42 -0.2449 -0.5761 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L16 mock treatment 1.00555093E8 2360000.0 0.2 8.1915862E7 -1.5E7 -1.31 -0.785 -0.5904 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L17 compound treatment 1.02140081E8 3940000.0 0.34 9.9114127E7 2190000.0 0.19 0.3761 0.9628 3189432 PK04_107231 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L18 compound treatment 9.5556171E7 -2640000.0 -0.23 9.8062929E7 1130000.0 0.1 -0.0911 -0.3662 3189547 PK04_107232 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L19 compound treatment 1.05301147E8 7100000.0 0.61 1.03186279E8 6260000.0 0.55 0.8211 0.9984 3071264 PK04_107233 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L20 compound treatment 1.00187166E8 1990000.0 0.17 1.0195563E8 5030000.0 0.44 0.4326 0.916 3189548 PK04_107234 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L21 compound treatment 1.04822724E8 6630000.0 0.57 1.07905814E8 1.1E7 0.96 1.084 0.9694 3189549 PK04_107235 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L22 compound treatment 1.03468198E8 5270000.0 0.46 1.02061371E8 5130000.0 0.45 0.6396 1.0 3071265 PK04_107236 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L23 mock treatment 1.14146025E8 1.59E7 1.38 1.07387445E8 1.05E7 0.92 1.6213 0.9803 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 L24 mock treatment 1.08336734E8 1.01E7 0.88 1.07677191E8 1.07E7 0.94 1.2844 0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M01 compound treatment 1.12214834E8 1.4E7 1.21 1.06005354E8 9080000.0 0.79 1.4178 0.9791 3189550 PK04_107237 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M02 compound treatment 9.9543305E7 1350000.0 0.12 9.5341026E7 -1590000.0 -0.14 -0.016 -0.0884 3071266 PK04_107238 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M03 compound treatment 1.05731991E8 7540000.0 0.65 1.06406766E8 9480000.0 0.83 1.0467 0.9928 3189551 PK04_107239 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M04 compound treatment 1.08266634E8 1.01E7 0.87 1.01027504E8 4100000.0 0.36 0.8687 0.9233 3189552 PK04_107240 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M05 compound treatment 8.8268849E7 -9930000.0 -0.86 1.03387678E8 6460000.0 0.57 -0.2066 -0.2012 3071267 PK04_107241 CN(C)S(=O)(=O)NCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M06 compound treatment 1.05183401E8 6990000.0 0.6 9.978492E7 2860000.0 0.25 0.6035 0.9239 3189553 PK04_107242 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M07 compound treatment 9.344656E7 -4750000.0 -0.41 9.6899561E7 -29300.0 0.0 -0.2919 -0.7115 3414058 PK04_107243 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M08 compound treatment 9.6279287E7 -1920000.0 -0.17 1.00064285E8 3140000.0 0.27 0.0769 0.24 3189554 PK04_107244 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M09 mock treatment 1.02275531E8 4080000.0 0.35 9.9801424E7 2870000.0 0.25 0.4269 0.9863 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M10 mock treatment 9.483208E7 -3360000.0 -0.29 8.7009552E7 -9920000.0 -0.87 -0.8193 -0.895 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M11 compound treatment 9.4271934E7 -3920000.0 -0.34 9.7709729E7 781000.0 0.07 -0.1914 -0.5534 3189555 PK04_107245 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M12 compound treatment 1.00182444E8 1990000.0 0.17 9.8971753E7 2040000.0 0.18 0.2477 0.9998 3071269 PK04_107246 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M13 mock treatment 9.093081E7 -7270000.0 -0.63 9.2383152E7 -4550000.0 -0.4 -0.7251 -0.9758 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M14 mock treatment 9.8841182E7 644000.0 0.06 9.2159788E7 -4770000.0 -0.42 -0.2558 -0.6074 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M15 compound treatment 9.1863318E7 -6330000.0 -0.55 9.3565386E7 -3360000.0 -0.29 -0.595 -0.9577 3189556 PK04_107247 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M16 compound treatment 9.0936709E7 -7260000.0 -0.63 8.7159915E7 -9770000.0 -0.85 -1.0479 -0.9884 3189557 PK04_107248 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M17 compound treatment 1.03677193E8 5480000.0 0.47 9.9515396E7 2590000.0 0.23 0.4948 0.943 3189558 PK04_107249 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M18 compound treatment 9.5215333E7 -2980000.0 -0.26 1.01642621E8 4710000.0 0.41 0.1096 0.2254 3071329 PK04_107250 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M19 compound treatment 9.7370614E7 -826000.0 -0.07 9.645973E7 -469000.0 -0.04 -0.0795 -0.9655 3189559 PK04_107251 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M20 compound treatment 9.8542174E7 345000.0 0.03 9.732174E7 393000.0 0.03 0.0454 0.9975 3071330 PK04_107252 CCCC#C[Si](O[C@H](CC)c1cn(Cc2cccc(Cl)c2)nn1)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M21 compound treatment 8.5371689E7 -1.28E7 -1.11 1.06719909E8 9790000.0 0.86 -0.1774 -0.1266 3189560 PK04_107253 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M22 compound treatment 9.6101395E7 -2100000.0 -0.18 9.7412758E7 484000.0 0.04 -0.098 -0.5274 3071331 PK04_107254 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M23 compound treatment 1.06165964E8 7970000.0 0.69 1.12088922E8 1.52E7 1.33 1.4249 0.9533 3189561 PK04_107255 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 M24 compound treatment 1.16934611E8 1.87E7 1.62 1.12708022E8 1.58E7 1.38 2.1209 0.9969 3071332 PK04_107256 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N01 compound treatment 1.19787755E8 2.16E7 1.86 9.8256359E7 1330000.0 0.12 1.4008 0.7497 3189562 PK04_107257 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N02 compound treatment 1.0232482E8 4130000.0 0.36 9.8997939E7 2070000.0 0.18 0.3802 0.9506 3189563 PK04_107258 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N03 compound treatment 1.01940959E8 3740000.0 0.32 9.4910435E7 -2020000.0 -0.18 0.1038 0.2816 3071333 PK04_107259 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N04 compound treatment 1.05675415E8 7480000.0 0.65 9.7480673E7 552000.0 0.05 0.4909 0.7579 3189564 PK04_107260 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N05 compound treatment 1.0250397E8 4310000.0 0.37 1.0632946E8 9400000.0 0.82 0.8448 0.9356 3189681 PK04_107261 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N06 compound treatment 9.5047998E7 -3150000.0 -0.27 9.2457292E7 -4470000.0 -0.39 -0.469 -0.9842 3071334 PK04_107262 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N07 compound treatment 1.08388019E8 1.02E7 0.88 1.00391069E8 3460000.0 0.3 0.8367 0.8988 3189682 PK04_107263 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N08 compound treatment 9.8956732E7 760000.0 0.07 9.7848026E7 919000.0 0.08 0.1033 0.9949 3071335 PK04_107264 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N09 mock treatment 9.4945304E7 -3250000.0 -0.28 9.2096778E7 -4830000.0 -0.42 -0.4976 -0.9802 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N10 mock treatment 9.6842974E7 -1350000.0 -0.12 9.563624E7 -1290000.0 -0.11 -0.1627 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N11 compound treatment 1.02594183E8 4400000.0 0.38 9.2593476E7 -4340000.0 -0.38 3.0E-4 5.0E-4 3189683 PK04_107265 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N12 compound treatment 9.315348E7 -5040000.0 -0.44 9.0152681E7 -6780000.0 -0.59 -0.7274 -0.9885 3189684 PK04_107266 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N13 mock treatment 9.2626953E7 -5570000.0 -0.48 1.03890552E8 6960000.0 0.61 0.0906 0.1168 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N14 mock treatment 9.778477E7 -412000.0 -0.04 9.8424518E7 1500000.0 0.13 0.0674 0.4969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N15 compound treatment 8.6759901E7 -1.14E7 -0.99 9.3094816E7 -3830000.0 -0.34 -0.9358 -0.897 3071336 PK04_107267 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N16 compound treatment 8.0135751E7 -1.81E7 -1.56 9.0359605E7 -6570000.0 -0.57 -1.5096 -0.908 3189685 PK04_107268 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N17 compound treatment 1.05166259E8 6970000.0 0.6 1.00643504E8 3710000.0 0.33 0.6555 0.9582 3189686 PK04_107269 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N18 compound treatment 9.0242867E7 -7950000.0 -0.69 8.7217487E7 -9710000.0 -0.85 -1.0868 -0.9944 3071337 PK04_107270 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N19 compound treatment 1.04497938E8 6300000.0 0.54 1.06083252E8 9150000.0 0.8 0.9514 0.9823 3189687 PK04_107271 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N20 compound treatment 9.8100673E7 -96100.0 -0.01 9.8741735E7 1810000.0 0.16 0.1063 0.6692 3189688 PK04_107272 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N21 compound treatment 8.6435508E7 -1.18E7 -1.02 9.9022347E7 2090000.0 0.18 -0.5888 -0.5704 3071339 PK04_107273 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N22 compound treatment 9.6254403E7 -1940000.0 -0.17 1.04125615E8 7200000.0 0.63 0.3267 0.5013 3189689 PK04_107274 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N23 compound treatment 1.08955697E8 1.08E7 0.93 1.08509206E8 1.16E7 1.01 1.3737 0.9991 3189690 PK04_107275 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 N24 compound treatment 1.04096109E8 5900000.0 0.51 9.9954832E7 3030000.0 0.26 0.5476 0.9535 3071341 PK04_107276 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O01 compound treatment 1.03300483E8 5100000.0 0.44 9.6935083E7 6240.0 0.0 0.3121 0.708 3414059 PK04_107277 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O02 compound treatment 1.04519741E8 6320000.0 0.55 9.6975656E7 46800.0 0.0 0.3891 0.7124 3189692 PK04_107278 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O03 compound treatment 1.06151687E8 7950000.0 0.69 1.03801207E8 6870000.0 0.6 0.9111 0.9978 3414060 PK04_107279 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O04 compound treatment 1.06876867E8 8680000.0 0.75 1.09463425E8 1.25E7 1.1 1.3058 0.9828 3189693 PK04_107280 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O05 compound treatment 1.09842537E8 1.16E7 1.01 1.03016314E8 6090000.0 0.53 1.088 0.9558 3071393 PK04_107281 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O06 compound treatment 1.24102971E8 2.59E7 2.24 1.13290698E8 1.64E7 1.43 2.5948 0.9767 3189694 PK04_107282 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O07 compound treatment 1.02191271E8 3990000.0 0.35 1.00351888E8 3420000.0 0.3 0.4558 0.9975 3189695 PK04_107283 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O08 compound treatment 1.00340207E8 2140000.0 0.19 9.6724972E7 -204000.0 -0.02 0.1183 0.636 3071395 PK04_107284 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O09 compound treatment 1.00515814E8 2320000.0 0.2 9.8628681E7 1700000.0 0.15 0.2468 0.9893 3189696 PK04_107285 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O10 compound treatment 1.02253657E8 4060000.0 0.35 9.7573248E7 644000.0 0.06 0.2877 0.8105 3189697 PK04_107286 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O11 mock treatment 1.00390038E8 2190000.0 0.19 9.7944157E7 1020000.0 0.09 0.1968 0.9405 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O12 mock treatment 9.8162258E7 -34500.0 0.0 9.5633336E7 -1300000.0 -0.11 -0.0823 -0.7254 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O13 compound treatment 1.04489464E8 6290000.0 0.54 1.03536965E8 6610000.0 0.58 0.7933 0.9995 3071396 PK04_107287 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O14 compound treatment 9.8810229E7 614000.0 0.05 9.8085242E7 1160000.0 0.1 0.109 0.9544 3187592 PK04_107288 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O15 compound treatment 1.21023208E8 2.28E7 1.97 1.13262667E8 1.63E7 1.43 2.4049 0.9875 3187593 PK04_107289 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O16 compound treatment 1.01192291E8 3000000.0 0.26 9.6903528E7 -25300.0 0.0 0.1814 0.701 3071397 PK04_107290 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O17 compound treatment 1.18850333E8 2.07E7 1.78 1.13526722E8 1.66E7 1.45 2.2886 0.9948 3187594 PK04_107291 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O18 compound treatment 1.11692844E8 1.35E7 1.17 1.11726696E8 1.48E7 1.3 1.74 0.9986 3071398 PK04_107292 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O19 compound treatment 1.08766633E8 1.06E7 0.91 1.07649598E8 1.07E7 0.94 1.309 0.9999 3187595 PK04_107293 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O20 compound treatment 1.0342141E8 5220000.0 0.45 1.04480451E8 7550000.0 0.66 0.7864 0.9827 3071399 PK04_107294 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O21 compound treatment 1.03104247E8 4910000.0 0.42 1.04045308E8 7120000.0 0.62 0.7401 0.9824 3187594 PK04_107295 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O22 compound treatment 1.11736478E8 1.35E7 1.17 1.12100429E8 1.52E7 1.33 1.7658 0.998 3187596 PK04_107296 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O23 compound treatment 1.10268853E8 1.21E7 1.04 1.07662923E8 1.07E7 0.94 1.4016 0.9986 3187597 PK04_107297 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 O24 compound treatment 1.20015952E8 2.18E7 1.88 1.13209626E8 1.63E7 1.42 2.3401 0.9905 3071400 PK04_107298 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P01 compound treatment 8.9243462E7 -8950000.0 -0.77 1.04336934E8 7410000.0 0.65 -0.0884 -0.0876 3187598 PK04_107299 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P02 compound treatment 1.00231845E8 2040000.0 0.18 9.1146981E7 -5780000.0 -0.51 -0.2335 -0.4359 3071401 PK04_107300 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P03 compound treatment 1.00122504E8 1930000.0 0.17 1.05389044E8 8460000.0 0.74 0.6412 0.8449 3187599 PK04_107301 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P04 compound treatment 1.07796474E8 9600000.0 0.83 9.704666E7 118000.0 0.01 0.5936 0.7158 3187600 PK04_107302 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P05 compound treatment 1.12364051E8 1.42E7 1.22 1.03516931E8 6590000.0 0.58 1.273 0.9411 3071402 PK04_107303 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P06 compound treatment 9.9763444E7 1570000.0 0.14 9.2554504E7 -4370000.0 -0.38 -0.175 -0.431 3187601 PK04_107304 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P07 compound treatment 1.06276926E8 8080000.0 0.7 1.01909283E8 4980000.0 0.44 0.8017 0.9743 3187602 PK04_107305 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P08 compound treatment 9.9637723E7 1440000.0 0.12 9.288748E7 -4040000.0 -0.35 -0.1621 -0.4323 3071403 PK04_107306 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P09 compound treatment 1.01432901E8 3240000.0 0.28 9.9552364E7 2620000.0 0.23 0.36 0.9952 3187603 PK04_107307 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P10 compound treatment 1.03314579E8 5120000.0 0.44 9.708166E7 153000.0 0.01 0.322 0.7282 3187604 PK04_107308 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P11 mock treatment 1.01246366E8 3050000.0 0.26 9.6893908E7 -34900.0 0.0 0.1841 0.6989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P12 mock treatment 1.02325081E8 4130000.0 0.36 9.5058673E7 -1870000.0 -0.16 0.1364 0.3477 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P13 compound treatment 1.06652219E8 8460000.0 0.73 1.04898429E8 7970000.0 0.7 1.0096 0.9997 3071404 PK04_107309 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P14 compound treatment 1.02326613E8 4130000.0 0.36 9.5826722E7 -1100000.0 -0.1 0.184 0.498 3187605 PK04_107310 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P15 compound treatment 1.07826144E8 9630000.0 0.83 1.03982664E8 7050000.0 0.62 1.0246 0.9892 3187606 PK04_107311 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P16 compound treatment 1.01244029E8 3050000.0 0.26 9.3676783E7 -3250000.0 -0.28 -0.0151 -0.0391 3071405 PK04_107312 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P17 compound treatment 1.09334334E8 1.11E7 0.96 1.04048249E8 7120000.0 0.62 1.1208 0.9779 3187607 PK04_107313 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P18 compound treatment 1.01488487E8 3290000.0 0.28 1.0055959E8 3630000.0 0.32 0.4257 0.9985 3187608 PK04_107314 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P19 compound treatment 1.09715101E8 1.15E7 0.99 1.07880348E8 1.1E7 0.96 1.3812 0.9998 3187728 PK04_107315 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P20 compound treatment 1.05714177E8 7520000.0 0.65 1.0329997E8 6370000.0 0.56 0.8534 0.9971 3071452 PK04_107316 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P21 compound treatment 1.08997595E8 1.08E7 0.93 1.07265075E8 1.03E7 0.9 1.2993 0.9999 3187729 PK04_107317 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P22 compound treatment 9.6985362E7 -1210000.0 -0.1 9.5773316E7 -1160000.0 -0.1 -0.1455 -0.9999 3187730 PK04_107318 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P23 compound treatment 1.10446293E8 1.22E7 1.06 1.09830475E8 1.29E7 1.13 1.5465 0.9995 3071453 PK04_107319 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2107 P24 compound treatment 9.7369925E7 -827000.0 -0.07 9.6425978E7 -503000.0 -0.04 -0.0816 -0.973 3187731 PK04_107320 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A01 compound treatment 1.12710678E8 1.39E7 1.2 9.9560327E7 505000.0 0.04 0.8781 0.7327 3187732 PK04_108001 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A02 compound treatment 9.3123848E7 -5720000.0 -0.49 8.3722541E7 -1.53E7 -1.34 -1.2982 -0.9079 3071454 PK04_108002 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A03 compound treatment 1.07428153E8 8580000.0 0.74 1.03077317E8 4020000.0 0.35 0.7732 0.9421 3187733 PK04_108003 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A04 compound treatment 9.6176077E7 -2670000.0 -0.23 9.8580273E7 -475000.0 -0.04 -0.1924 -0.8213 3071455 PK04_108004 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A05 compound treatment 1.06086904E8 7240000.0 0.63 9.1210091E7 -7840000.0 -0.69 -0.0432 -0.0465 3187734 PK04_108005 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A06 compound treatment 9.7955763E7 -889000.0 -0.08 9.3585108E7 -5470000.0 -0.48 -0.3928 -0.8102 3071456 PK04_108006 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A07 compound treatment 1.04909288E8 6060000.0 0.52 1.05036313E8 5980000.0 0.52 0.7405 1.0 3187735 PK04_108007 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A08 compound treatment 9.308085E7 -5760000.0 -0.5 9.8885005E7 -170000.0 -0.01 -0.3625 -0.7279 3071457 PK04_108008 CC(=CCN[C@H](CO)c1ccccc1)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A09 compound treatment 1.02004591E8 3160000.0 0.27 9.2412925E7 -6640000.0 -0.58 -0.218 -0.3395 3187736 PK04_108009 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A10 compound treatment 1.01405075E8 2560000.0 0.22 9.8152428E7 -902000.0 -0.08 0.1005 0.4281 3071458 PK04_108010 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A11 compound treatment 8.9768003E7 -9080000.0 -0.78 9.72192E7 -1840000.0 -0.16 -0.668 -0.8347 3071459 PK04_108011 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A12 compound treatment 7.294876E7 -2.59E7 -2.24 6.5877865E7 -3.32E7 -2.9 -3.6347 -0.9917 3187737 PK04_108012 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A13 mock treatment 9.9757303E7 913000.0 0.08 9.0965076E7 -8090000.0 -0.71 -0.4449 -0.6245 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A14 mock treatment 9.6347937E7 -2500000.0 -0.22 9.6892876E7 -2160000.0 -0.19 -0.2863 -0.9979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A15 compound treatment 9.3267188E7 -5580000.0 -0.48 9.839078E7 -664000.0 -0.06 -0.3817 -0.7867 3187738 PK04_108013 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A16 compound treatment 1.04705041E8 5860000.0 0.51 1.01980804E8 2930000.0 0.26 0.539 0.9502 3071460 PK04_108014 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A17 compound treatment 1.03139318E8 4290000.0 0.37 9.4736181E7 -4320000.0 -0.38 -0.005 -0.0094 3187739 PK04_108015 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A18 compound treatment 1.00812921E8 1970000.0 0.17 1.04223703E8 5170000.0 0.45 0.4401 0.9107 3071461 PK04_108016 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A19 compound treatment 9.3831589E7 -5010000.0 -0.43 1.05290308E8 6240000.0 0.55 0.0797 0.1144 3187740 PK04_108017 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A20 compound treatment 1.00381337E8 1540000.0 0.13 1.01971506E8 2920000.0 0.26 0.2743 0.9536 3071462 PK04_108018 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A21 compound treatment 1.06259262E8 7410000.0 0.64 9.7193418E7 -1860000.0 -0.16 0.3376 0.511 3187741 PK04_108019 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A22 compound treatment 1.1875518E8 1.99E7 1.72 1.08259397E8 9200000.0 0.81 1.7856 0.9403 3071463 PK04_108020 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A23 compound treatment 1.07542685E8 8700000.0 0.75 1.0270853E8 3650000.0 0.32 0.7573 0.9275 3187742 PK04_108021 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 A24 compound treatment 1.07344902E8 8500000.0 0.73 1.05382539E8 6330000.0 0.55 0.9107 0.9903 3071464 PK04_108022 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B01 compound treatment 1.09679966E8 1.08E7 0.94 1.06315804E8 7260000.0 0.64 1.1111 0.9822 2133065 PK04_108023 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B02 compound treatment 1.06382064E8 7540000.0 0.65 1.01492559E8 2440000.0 0.21 0.6112 0.8921 3071465 PK04_108024 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B03 compound treatment 9.3474981E7 -5370000.0 -0.46 1.02138167E8 3080000.0 0.27 -0.1371 -0.2556 2133224 PK04_108025 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B04 compound treatment 9.8229806E7 -615000.0 -0.05 8.7423571E7 -1.16E7 -1.02 -0.7574 -0.743 1952196 PK04_108026 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B05 compound treatment 7.6515817E7 -2.23E7 -1.93 6.8346058E7 -3.07E7 -2.69 -3.2641 -0.9868 2133510 PK04_108027 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B06 compound treatment 1.01789879E8 2950000.0 0.25 9.967986E7 625000.0 0.05 0.2186 0.8399 3071510 PK04_108028 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B07 compound treatment 9.2506615E7 -6340000.0 -0.55 1.04401035E8 5350000.0 0.47 -0.0563 -0.0781 2128988 PK04_108029 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B08 compound treatment 1.04946232E8 6100000.0 0.53 8.9338962E7 -9720000.0 -0.85 -0.2286 -0.2285 3187870 PK04_108030 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B09 compound treatment 9.9002281E7 158000.0 0.01 9.6902924E7 -2150000.0 -0.19 -0.1235 -0.6543 3187871 PK04_108031 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B10 compound treatment 1.00492994E8 1650000.0 0.14 9.5063624E7 -3990000.0 -0.35 -0.1463 -0.3879 3071511 PK04_108032 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B11 compound treatment 9.2951524E7 -5890000.0 -0.51 1.01548204E8 2490000.0 0.22 -0.2056 -0.3713 2129008 PK04_108033 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B12 compound treatment 9.3246112E7 -5600000.0 -0.48 8.3013676E7 -1.6E7 -1.4 -1.3346 -0.8988 3187872 PK04_108034 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B13 mock treatment 1.00699992E8 1860000.0 0.16 9.8551989E7 -503000.0 -0.04 0.0822 0.4946 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B14 mock treatment 9.5532485E7 -3310000.0 -0.29 9.2710212E7 -6340000.0 -0.56 -0.5949 -0.9524 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B15 compound treatment 9.3924147E7 -4920000.0 -0.42 9.6523801E7 -2530000.0 -0.22 -0.4572 -0.9539 3187873 PK04_108035 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CCC\C=C\CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B16 compound treatment 9.6502759E7 -2340000.0 -0.2 8.2113111E7 -1.69E7 -1.48 -1.1915 -0.7962 3414061 PK04_108036 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B17 compound treatment 9.8229388E7 -615000.0 -0.05 9.7705183E7 -1350000.0 -0.12 -0.1211 -0.935 3187874 PK04_108037 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B18 compound treatment 9.9687776E7 843000.0 0.07 1.00075706E8 1020000.0 0.09 0.1147 0.9949 3071513 PK04_108038 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B19 compound treatment 9.2002747E7 -6840000.0 -0.59 1.04010842E8 4960000.0 0.43 -0.1112 -0.1517 3187875 PK04_108039 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B20 compound treatment 9.6240981E7 -2600000.0 -0.22 9.1871012E7 -7180000.0 -0.63 -0.6036 -0.9039 3071514 PK04_108040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B21 compound treatment 1.03460145E8 4620000.0 0.4 1.064123E8 7360000.0 0.64 0.7372 0.9734 3187876 PK04_108041 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B22 compound treatment 1.12961262E8 1.41E7 1.22 1.08836919E8 9780000.0 0.86 1.4675 0.985 3071515 PK04_108042 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B23 compound treatment 9.9447524E7 603000.0 0.05 1.08198814E8 9140000.0 0.8 0.6027 0.7515 3187877 PK04_108043 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 B24 compound treatment 1.07344811E8 8500000.0 0.73 9.8809156E7 -246000.0 -0.02 0.5039 0.6861 3071516 PK04_108044 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C01 compound treatment 1.10439238E8 1.16E7 1.0 1.07979169E8 8920000.0 0.78 1.2604 0.9924 3187878 PK04_108045 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C02 compound treatment 1.02079993E8 3240000.0 0.28 1.02655239E8 3600000.0 0.32 0.4204 0.9982 3071464 PK04_108046 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C03 compound treatment 9.273443E7 -6110000.0 -0.53 9.2798516E7 -6260000.0 -0.55 -0.7604 -0.9998 3187879 PK04_108047 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C04 compound treatment 1.05158385E8 6310000.0 0.55 9.7138566E7 -1920000.0 -0.17 0.267 0.468 3071517 PK04_108048 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C05 compound treatment 1.02485178E8 3640000.0 0.31 9.4335701E7 -4720000.0 -0.41 -0.0697 -0.1343 3071518 PK04_108049 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C06 compound treatment 9.3723794E7 -5120000.0 -0.44 9.8429431E7 -625000.0 -0.05 -0.3515 -0.7886 3187880 PK04_108050 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C07 compound treatment 1.00846217E8 2000000.0 0.17 9.1494655E7 -7560000.0 -0.66 -0.3456 -0.5054 3187881 PK04_108051 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C08 compound treatment 5.6883843E7 -4.2E7 -3.62 4.688453E7 -5.22E7 -4.57 -5.7913 -0.9935 3071519 PK04_108052 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C09 compound treatment 9.7956693E7 -888000.0 -0.08 9.7080266E7 -1970000.0 -0.17 -0.1764 -0.9332 3187882 PK04_108053 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C10 compound treatment 8.4347153E7 -1.45E7 -1.25 9.4202577E7 -4850000.0 -0.42 -1.1857 -0.8967 3071520 PK04_108054 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C11 mock treatment 9.714067E7 -1700000.0 -0.15 8.7469304E7 -1.16E7 -1.01 -0.821 -0.8013 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C12 mock treatment 9.2949519E7 -5900000.0 -0.51 9.632595E7 -2730000.0 -0.24 -0.5289 -0.9405 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C13 compound treatment 9.5534513E7 -3310000.0 -0.29 9.8565483E7 -489000.0 -0.04 -0.2325 -0.8041 3187883 PK04_108055 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C14 compound treatment 8.7043336E7 -1.18E7 -1.02 9.9899124E7 844000.0 0.07 -0.6685 -0.6541 3071521 PK04_108056 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C15 mock treatment 9.5524344E7 -3320000.0 -0.29 9.1015645E7 -8040000.0 -0.7 -0.7003 -0.9217 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C16 mock treatment 9.6949936E7 -1890000.0 -0.16 9.4943564E7 -4110000.0 -0.36 -0.3701 -0.9364 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C17 compound treatment 8.9929009E7 -8920000.0 -0.77 9.0999815E7 -8060000.0 -0.7 -1.043 -0.999 3188001 PK04_108057 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C18 compound treatment 9.505194E7 -3790000.0 -0.33 1.03826896E8 4770000.0 0.42 0.0637 0.12 3071522 PK04_108058 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C19 compound treatment 9.939538E7 551000.0 0.05 9.2417552E7 -6640000.0 -0.58 -0.3771 -0.647 3188002 PK04_108059 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C20 compound treatment 1.06324824E8 7480000.0 0.65 1.05601271E8 6550000.0 0.57 0.862 0.9982 3071523 PK04_108060 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C21 compound treatment 1.00644355E8 1800000.0 0.16 1.02933674E8 3880000.0 0.34 0.3499 0.9373 3188003 PK04_108061 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C22 compound treatment 8.9267161E7 -9580000.0 -0.83 9.5368147E7 -3690000.0 -0.32 -0.8131 -0.9157 3071524 PK04_108062 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C23 compound treatment 1.04145503E8 5300000.0 0.46 9.4757497E7 -4300000.0 -0.38 0.0578 0.0976 3188004 PK04_108063 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 C24 compound treatment 1.12824702E8 1.4E7 1.21 1.09275189E8 1.02E7 0.89 1.4863 0.9891 3071525 PK04_108064 CCOC(=O)C1OC[C@H](N1CC#C)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D01 compound treatment 9.8673643E7 -171000.0 -0.01 9.8871498E7 -183000.0 -0.02 -0.0218 -0.9991 3188005 PK04_108065 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D02 compound treatment 1.06257864E8 7410000.0 0.64 9.6867278E7 -2190000.0 -0.19 0.3174 0.4749 3414062 PK04_108066 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D03 compound treatment 1.00906773E8 2060000.0 0.18 1.00719776E8 1660000.0 0.15 0.229 0.995 3188006 PK04_108067 CC(C)C[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D04 compound treatment 1.10465322E8 1.16E7 1.0 1.04935276E8 5880000.0 0.51 1.0736 0.9518 3071527 PK04_108068 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D05 compound treatment 9.604136E7 -2800000.0 -0.24 1.00705382E8 1650000.0 0.14 -0.0691 -0.245 3188007 PK04_108069 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D06 compound treatment 1.09092002E8 1.02E7 0.89 9.5813686E7 -3240000.0 -0.28 0.4253 0.4576 3071528 PK04_108070 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D07 compound treatment 9.7291241E7 -1550000.0 -0.13 9.5758443E7 -3300000.0 -0.29 -0.2989 -0.9393 3188008 PK04_108071 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D08 compound treatment 9.4133501E7 -4710000.0 -0.41 9.3273375E7 -5780000.0 -0.51 -0.6455 -0.9942 3071529 PK04_108072 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D09 compound treatment 9.0497087E7 -8350000.0 -0.72 9.8321431E7 -733000.0 -0.06 -0.5552 -0.767 3188009 PK04_108073 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)CNC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D10 compound treatment 9.5929118E7 -2920000.0 -0.25 8.7712121E7 -1.13E7 -0.99 -0.88 -0.8593 3071530 PK04_108074 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D11 mock treatment 1.00252534E8 1410000.0 0.12 9.9971167E7 916000.0 0.08 0.1427 0.9796 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D12 mock treatment 8.5938625E7 -1.29E7 -1.11 9.6913362E7 -2140000.0 -0.19 -0.9208 -0.8146 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D13 compound treatment 9.9763532E7 919000.0 0.08 1.03133551E8 4080000.0 0.36 0.3085 0.8437 3188010 PK04_108075 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D14 compound treatment 8.4465608E7 -1.44E7 -1.24 8.3499307E7 -1.56E7 -1.36 -1.8408 -0.9989 3071531 PK04_108076 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D15 mock treatment 9.7899318E7 -945000.0 -0.08 9.8580594E7 -474000.0 -0.04 -0.0871 -0.9508 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D16 mock treatment 8.6921562E7 -1.19E7 -1.03 9.7648256E7 -1410000.0 -0.12 -0.8152 -0.786 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D17 compound treatment 9.3061645E7 -5780000.0 -0.5 9.6613244E7 -2440000.0 -0.21 -0.5043 -0.9282 3071578 PK04_108077 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D18 compound treatment 4.5868751E7 -5.3E7 -4.58 3.5586421E7 -6.35E7 -5.55 -7.1632 -0.9954 3071579 PK04_108078 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D19 compound treatment 9.3769091E7 -5080000.0 -0.44 9.4143853E7 -4910000.0 -0.43 -0.6139 -1.0 3071580 PK04_108079 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc6ccccc6)NC2=O)[C@@H]7O[C@]7(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D20 compound treatment 3.5698805E7 -6.31E7 -5.45 3.104975E7 -6.8E7 -5.95 -8.0651 -0.999 3188011 PK04_108080 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D21 compound treatment 1.06399572E8 7550000.0 0.65 1.0828356E8 9230000.0 0.81 1.0325 0.9944 3188012 PK04_108081 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D22 compound treatment 9.7864282E7 -980000.0 -0.08 9.0606676E7 -8450000.0 -0.74 -0.5827 -0.783 3071581 PK04_108082 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D23 compound treatment 9.3828015E7 -5020000.0 -0.43 9.9237734E7 183000.0 0.02 -0.2951 -0.6805 3188013 PK04_108083 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 D24 compound treatment 1.02923721E8 4080000.0 0.35 1.04172977E8 5120000.0 0.45 0.5659 0.9929 3071582 PK04_108084 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E01 mock treatment 1.09632422E8 1.08E7 0.93 9.7834164E7 -1220000.0 -0.11 0.5833 0.622 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E02 mock treatment 1.05654481E8 6810000.0 0.59 9.8523729E7 -531000.0 -0.05 0.383 0.6492 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E03 compound treatment 1.03074498E8 4230000.0 0.37 1.01171405E8 2120000.0 0.19 0.3893 0.9504 3188014 PK04_108085 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E04 compound treatment 9.6067077E7 -2780000.0 -0.24 8.9729366E7 -9330000.0 -0.82 -0.7467 -0.8778 3071583 PK04_108086 C/C=C/CN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E05 compound treatment 1.0152535E8 2680000.0 0.23 9.9660482E7 606000.0 0.05 0.2012 0.8471 3188015 PK04_108087 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E06 compound treatment 9.9096946E7 252000.0 0.02 9.0756072E7 -8300000.0 -0.73 -0.4982 -0.6856 3071584 PK04_108088 OCC(NCC#C)/C=C/c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E07 compound treatment 9.9679384E7 835000.0 0.07 9.7536582E7 -1520000.0 -0.13 -0.043 -0.2843 3188129 PK04_108089 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E08 compound treatment 9.5189538E7 -3660000.0 -0.32 9.493241E7 -4120000.0 -0.36 -0.4784 -0.9978 3071585 PK04_108090 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E09 mock treatment 9.5288812E7 -3560000.0 -0.31 9.5699394E7 -3360000.0 -0.29 -0.4248 -0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E10 mock treatment 8.8712433E7 -1.01E7 -0.88 9.4227955E7 -4830000.0 -0.42 -0.9175 -0.9442 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E11 compound treatment 9.7680692E7 -1160000.0 -0.1 9.5562558E7 -3490000.0 -0.31 -0.2872 -0.8926 3071586 PK04_108091 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E12 compound treatment 8.0644726E7 -1.82E7 -1.57 9.3887277E7 -5170000.0 -0.45 -1.4313 -0.875 3188130 PK04_108092 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E13 compound treatment 9.6283169E7 -2560000.0 -0.22 9.7135164E7 -1920000.0 -0.17 -0.2752 -0.9908 3188131 PK04_108093 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E14 compound treatment 9.1101517E7 -7740000.0 -0.67 9.509853E7 -3960000.0 -0.35 -0.7177 -0.953 3071587 PK04_108094 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E15 compound treatment 9.6624668E7 -2220000.0 -0.19 1.00567512E8 1510000.0 0.13 -0.042 -0.1802 3188132 PK04_108095 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E16 compound treatment 8.9536998E7 -9310000.0 -0.8 9.6489513E7 -2570000.0 -0.22 -0.7272 -0.8712 3071588 PK04_108096 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E17 mock treatment 9.6979601E7 -1870000.0 -0.16 1.04937236E8 5880000.0 0.51 0.2501 0.4637 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E18 mock treatment 8.5925599E7 -1.29E7 -1.12 1.06231488E8 7180000.0 0.63 -0.3449 -0.2694 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E19 compound treatment 9.5894852E7 -2950000.0 -0.25 1.02489337E8 3430000.0 0.3 0.0324 0.0822 3188133 PK04_108097 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E20 compound treatment 9.5773571E7 -3070000.0 -0.27 9.5245292E7 -3810000.0 -0.33 -0.4233 -0.9936 3071589 PK04_108098 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E21 compound treatment 1.02577887E8 3730000.0 0.32 1.05593204E8 6540000.0 0.57 0.6326 0.9632 3188134 PK04_108099 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E22 compound treatment 9.7486727E7 -1360000.0 -0.12 9.9480644E7 426000.0 0.04 -0.0566 -0.4598 3071590 PK04_108100 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E23 compound treatment 1.03563666E8 4720000.0 0.41 1.04230178E8 5180000.0 0.45 0.6085 0.9986 3188135 PK04_108101 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 E24 compound treatment 9.8726913E7 -118000.0 -0.01 9.9228771E7 174000.0 0.02 0.0036 0.1948 3071591 PK04_108102 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F01 mock treatment 1.09947009E8 1.11E7 0.96 1.04593423E8 5540000.0 0.48 1.0208 0.9501 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F02 mock treatment 1.04811118E8 5970000.0 0.52 9.6598809E7 -2460000.0 -0.21 0.2124 0.3804 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F03 compound treatment 1.03074351E8 4230000.0 0.37 1.00263768E8 1210000.0 0.11 0.3331 0.8759 3188136 PK04_108103 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F04 compound treatment 9.6460591E7 -2380000.0 -0.21 9.4305911E7 -4750000.0 -0.42 -0.4395 -0.9475 3071592 PK04_108104 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F05 compound treatment 9.6930214E7 -1910000.0 -0.17 1.00535764E8 1480000.0 0.13 -0.0253 -0.1203 3188137 PK04_108105 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F06 compound treatment 9.7529153E7 -1320000.0 -0.11 9.4038876E7 -5020000.0 -0.44 -0.3908 -0.8617 3071592 PK04_108106 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F07 compound treatment 1.01401185E8 2560000.0 0.22 1.01742977E8 2690000.0 0.24 0.3225 0.9995 3071593 PK04_108107 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F08 compound treatment 8.7186508E7 -1.17E7 -1.01 8.9090976E7 -9960000.0 -0.87 -1.3286 -0.9974 3188138 PK04_108108 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F09 mock treatment 1.00378982E8 1530000.0 0.13 9.8475122E7 -580000.0 -0.05 0.0578 0.4075 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F10 mock treatment 9.3702552E7 -5140000.0 -0.44 9.4245975E7 -4810000.0 -0.42 -0.6117 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F11 compound treatment 9.8278505E7 -566000.0 -0.05 1.00034116E8 979000.0 0.09 0.026 0.2637 3188139 PK04_108109 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F12 compound treatment 9.1623922E7 -7220000.0 -0.62 9.8393412E7 -662000.0 -0.06 -0.4819 -0.7694 3071594 PK04_108110 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F13 compound treatment 9.7010644E7 -1830000.0 -0.16 1.00503325E8 1450000.0 0.13 -0.0224 -0.1103 3188140 PK04_108111 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F14 compound treatment 9.424301E7 -4600000.0 -0.4 9.6163098E7 -2890000.0 -0.25 -0.46 -0.9762 3414064 PK04_108112 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F15 compound treatment 9.7498033E7 -1350000.0 -0.12 1.01987553E8 2930000.0 0.26 0.0992 0.3522 3071596 PK04_108113 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F16 compound treatment 9.2582207E7 -6260000.0 -0.54 1.01926161E8 2870000.0 0.25 -0.2048 -0.3434 3188141 PK04_108114 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F17 mock treatment 1.03587189E8 4740000.0 0.41 1.06834331E8 7780000.0 0.68 0.7711 0.9704 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F18 mock treatment 8.7876239E7 -1.1E7 -0.95 1.05479633E8 6420000.0 0.56 -0.2723 -0.2472 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F19 compound treatment 9.9847385E7 1000000.0 0.09 1.00940605E8 1890000.0 0.17 0.1779 0.9547 3188142 PK04_108115 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F20 compound treatment 9.155253E7 -7290000.0 -0.63 9.1012184E7 -8040000.0 -0.7 -0.9431 -0.9985 3071597 PK04_108116 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F21 compound treatment 1.02761435E8 3920000.0 0.34 1.04196926E8 5140000.0 0.45 0.5574 0.9901 3188143 PK04_108117 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F22 compound treatment 9.9444108E7 599000.0 0.05 1.0029469E8 1240000.0 0.11 0.1133 0.9427 3071598 PK04_108118 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F23 compound treatment 1.06664393E8 7820000.0 0.68 1.07838167E8 8780000.0 0.77 1.0211 0.9979 3188144 PK04_108119 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@@H](C)NC4=O)[C@@H]5O[C@@]51C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 F24 compound treatment 4.5706207E7 -5.31E7 -4.59 3.7890119E7 -6.12E7 -5.35 -7.0305 -0.9971 3188260 PK04_108120 CC(=O)O[C@@H]([C@@H]1CCCN1S(=O)(=O)c2ccccc2[N+](=O)[O-])C(=C)C3=CCN(C3)S(=O)(=O)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G01 compound treatment 1.00958081E8 2110000.0 0.18 1.02640897E8 3590000.0 0.31 0.351 0.9668 3071599 PK04_108121 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G02 compound treatment 9.6799611E7 -2050000.0 -0.18 9.0185838E7 -8870000.0 -0.78 -0.6738 -0.8464 3188261 PK04_108122 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G03 mock treatment 1.07644044E8 8800000.0 0.76 1.00086017E8 1030000.0 0.09 0.6012 0.7855 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G04 mock treatment 9.9749711E7 905000.0 0.08 9.2417475E7 -6640000.0 -0.58 -0.3555 -0.6065 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G05 compound treatment 1.00225811E8 1380000.0 0.12 9.127019E7 -7780000.0 -0.68 -0.3974 -0.5746 3188262 PK04_108123 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G06 compound treatment 9.5467987E7 -3380000.0 -0.29 9.1446696E7 -7610000.0 -0.67 -0.6771 -0.9314 3071600 PK04_108124 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G07 compound treatment 1.02443284E8 3600000.0 0.31 9.6917403E7 -2140000.0 -0.19 0.0875 0.2412 3189036 PK04_108125 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G08 compound treatment 9.6972624E7 -1870000.0 -0.16 9.3658465E7 -5400000.0 -0.47 -0.4483 -0.898 3071601 PK04_108126 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G09 compound treatment 9.4178276E7 -4670000.0 -0.4 9.8111334E7 -944000.0 -0.08 -0.3434 -0.8346 3188263 PK04_108127 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G10 compound treatment 9.7051066E7 -1790000.0 -0.15 9.4453142E7 -4600000.0 -0.4 -0.3943 -0.9138 3071602 PK04_108128 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G11 compound treatment 9.9763601E7 919000.0 0.08 9.5846514E7 -3210000.0 -0.28 -0.1424 -0.4881 3188264 PK04_108129 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G12 compound treatment 9.6171358E7 -2670000.0 -0.23 9.3030466E7 -6020000.0 -0.53 -0.5361 -0.9314 3071603 PK04_108130 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G13 compound treatment 9.87345E7 -110000.0 -0.01 9.8719027E7 -336000.0 -0.03 -0.0275 -0.8905 3188265 PK04_108131 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G14 compound treatment 9.1171302E7 -7670000.0 -0.66 9.5800405E7 -3250000.0 -0.28 -0.6701 -0.9288 3071604 PK04_108132 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G15 compound treatment 9.663804E7 -2210000.0 -0.19 9.7088504E7 -1970000.0 -0.17 -0.2565 -0.9987 3188266 PK04_108133 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G16 compound treatment 9.1005599E7 -7840000.0 -0.68 9.2470932E7 -6580000.0 -0.58 -0.8862 -0.9968 3071651 PK04_108134 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G17 compound treatment 9.9652182E7 807000.0 0.07 9.9361083E7 306000.0 0.03 0.0683 0.9137 3188267 PK04_108135 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G18 compound treatment 9.5034581E7 -3810000.0 -0.33 9.6115183E7 -2940000.0 -0.26 -0.4146 -0.9926 3071652 PK04_108136 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G19 mock treatment 1.01703231E8 2860000.0 0.25 1.02548561E8 3490000.0 0.31 0.3908 0.9944 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G20 mock treatment 9.8385659E7 -459000.0 -0.04 9.9081029E7 26100.0 0.0 -0.0264 -0.6652 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G21 compound treatment 1.04013679E8 5170000.0 0.45 1.03673567E8 4620000.0 0.4 0.6015 0.9988 3189164 PK04_108137 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G22 compound treatment 9.6750789E7 -2090000.0 -0.18 9.6171919E7 -2880000.0 -0.25 -0.3063 -0.9867 3071653 PK04_108138 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G23 compound treatment 1.08058597E8 9210000.0 0.8 1.09176689E8 1.01E7 0.89 1.1891 0.9986 3189167 PK04_108139 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 G24 compound treatment 1.08178436E8 9330000.0 0.81 1.07098959E8 8040000.0 0.7 1.0679 0.9977 3188268 PK04_108140 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H01 compound treatment 1.10316977E8 1.15E7 0.99 1.09263376E8 1.02E7 0.89 1.3324 0.9987 3188269 PK04_108141 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H02 compound treatment 1.00607891E8 1760000.0 0.15 9.3767933E7 -5290000.0 -0.46 -0.2195 -0.4506 3071654 PK04_108142 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H03 mock treatment 1.08600551E8 9760000.0 0.84 1.02017318E8 2960000.0 0.26 0.7792 0.8838 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H04 mock treatment 9.3756251E7 -5090000.0 -0.44 9.4605616E7 -4450000.0 -0.39 -0.5861 -0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H05 compound treatment 1.04416543E8 5570000.0 0.48 9.9029412E7 -25500.0 0.0 0.3387 0.7038 3188270 PK04_108143 CC(C)C[C@@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H06 compound treatment 9.6923817E7 -1920000.0 -0.17 9.5235722E7 -3820000.0 -0.33 -0.3537 -0.9478 3071655 PK04_108144 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H07 compound treatment 1.01260775E8 2420000.0 0.21 9.8374079E7 -681000.0 -0.06 0.1054 0.4858 3188271 PK04_108145 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H08 compound treatment 9.5704566E7 -3140000.0 -0.27 9.7043698E7 -2010000.0 -0.18 -0.3162 -0.9781 3071656 PK04_108146 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H09 compound treatment 9.4445674E7 -4400000.0 -0.38 9.4970142E7 -4080000.0 -0.36 -0.5215 -0.9995 3188272 PK04_108147 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H10 compound treatment 9.1022543E7 -7820000.0 -0.68 9.1549895E7 -7510000.0 -0.66 -0.9422 -0.9999 3071529 PK04_108148 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H11 compound treatment 9.8820839E7 -23800.0 0.0 9.48339E7 -4220000.0 -0.37 -0.2627 -0.711 3188273 PK04_108149 CC(C)C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC1=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H12 compound treatment 9.9070545E7 226000.0 0.02 9.5181107E7 -3870000.0 -0.34 -0.2259 -0.6653 3071527 PK04_108150 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H13 compound treatment 9.701488E7 -1830000.0 -0.16 1.02175568E8 3120000.0 0.27 0.0814 0.2579 3071658 PK04_108151 CC(C)C[C@H]1NC(=O)[C@@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H14 compound treatment 9.6691095E7 -2150000.0 -0.19 9.7157963E7 -1900000.0 -0.17 -0.2489 -0.9984 3188274 PK04_108152 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H15 compound treatment 9.9383898E7 539000.0 0.05 9.870654E7 -348000.0 -0.03 0.0114 0.2043 3188275 PK04_108153 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H16 compound treatment 9.5854925E7 -2990000.0 -0.26 9.7519297E7 -1540000.0 -0.13 -0.2776 -0.9537 3071661 PK04_108154 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H17 compound treatment 9.8945993E7 101000.0 0.01 9.7308952E7 -1750000.0 -0.15 -0.1019 -0.6655 3188391 PK04_108155 CC(C)C[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H18 compound treatment 9.5340978E7 -3500000.0 -0.3 1.01217997E8 2160000.0 0.19 -0.0801 -0.2245 3071664 PK04_108156 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H19 mock treatment 1.06012253E8 7170000.0 0.62 1.04242225E8 5190000.0 0.45 0.7588 0.9884 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H20 mock treatment 9.8479931E7 -365000.0 -0.03 1.00105474E8 1050000.0 0.09 0.0427 0.4397 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H21 compound treatment 1.03615399E8 4770000.0 0.41 1.06315204E8 7260000.0 0.64 0.7407 0.978 3188392 PK04_108157 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H22 compound treatment 1.03359447E8 4510000.0 0.39 1.00340409E8 1290000.0 0.11 0.3553 0.8754 3071666 PK04_108158 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H23 compound treatment 1.08514641E8 9670000.0 0.84 9.849933E7 -556000.0 -0.05 0.5562 0.6648 3188393 PK04_108159 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H]6CCCN6C2=O)[C@@H]7O[C@]7(C)[C@H]4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 H24 compound treatment 1.01872412E8 3030000.0 0.26 1.04441772E8 5390000.0 0.47 0.5183 0.9613 3071711 PK04_108160 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I01 compound treatment 1.11333844E8 1.25E7 1.08 1.00184365E8 1130000.0 0.1 0.8327 0.7687 3188394 PK04_108161 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I02 compound treatment 1.0225161E8 3410000.0 0.29 9.4451555E7 -4600000.0 -0.4 -0.0768 -0.1539 3071714 PK04_108162 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I03 compound treatment 1.03360696E8 4520000.0 0.39 9.9255305E7 200000.0 0.02 0.2882 0.7382 3188395 PK04_108163 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I04 compound treatment 9.9067103E7 222000.0 0.02 9.2398577E7 -6660000.0 -0.58 -0.3983 -0.6834 3071715 PK04_108164 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I05 mock treatment 1.01923509E8 3080000.0 0.27 9.7968219E7 -1090000.0 -0.1 0.1208 0.4277 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I06 mock treatment 9.805896E7 -786000.0 -0.07 9.6075758E7 -2980000.0 -0.26 -0.2324 -0.8624 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I07 compound treatment 9.966451E7 820000.0 0.07 1.00306623E8 1250000.0 0.11 0.1275 0.9777 3188396 PK04_108165 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I08 compound treatment 9.5343357E7 -3500000.0 -0.3 9.5328263E7 -3730000.0 -0.33 -0.4445 -0.9993 3071717 PK04_108166 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I09 compound treatment 9.7397328E7 -1450000.0 -0.13 9.9405878E7 351000.0 0.03 -0.0667 -0.518 3188397 PK04_108167 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I10 compound treatment 9.7005332E7 -1840000.0 -0.16 9.4382759E7 -4670000.0 -0.41 -0.4015 -0.9152 3071720 PK04_108168 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I11 compound treatment 9.8108365E7 -736000.0 -0.06 1.00770752E8 1720000.0 0.15 0.0612 0.3754 3188398 PK04_108169 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I12 compound treatment 9.0382957E7 -8460000.0 -0.73 9.3289722E7 -5770000.0 -0.5 -0.8736 -0.9836 3071724 PK04_108170 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I13 compound treatment 9.6381897E7 -2460000.0 -0.21 9.8845025E7 -210000.0 -0.02 -0.1634 -0.7653 3071725 PK04_108171 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I14 compound treatment 9.8080336E7 -764000.0 -0.07 9.9331796E7 277000.0 0.02 -0.0295 -0.4202 3071727 PK04_108172 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I15 compound treatment 9.2233825E7 -6610000.0 -0.57 9.3327343E7 -5730000.0 -0.5 -0.7582 -0.9979 3188399 PK04_108173 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I16 compound treatment 9.2080689E7 -6760000.0 -0.58 9.6264803E7 -2790000.0 -0.24 -0.5858 -0.9251 3071766 PK04_108174 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I17 compound treatment 9.8802902E7 -41800.0 0.0 1.02836455E8 3780000.0 0.33 0.2315 0.6994 3188400 PK04_108175 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I18 compound treatment 9.5930594E7 -2910000.0 -0.25 1.02025879E8 2970000.0 0.26 0.0059 0.0162 3071767 PK04_108176 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I19 compound treatment 9.1078508E7 -7770000.0 -0.67 8.9234466E7 -9820000.0 -0.86 -1.082 -0.9925 3188401 PK04_108177 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I20 compound treatment 9.6507212E7 -2340000.0 -0.2 1.01902797E8 2850000.0 0.25 0.0335 0.1044 3071770 PK04_108178 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I21 mock treatment 1.02483072E8 3640000.0 0.31 1.03512837E8 4460000.0 0.39 0.4981 0.9942 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I22 mock treatment 1.01451232E8 2610000.0 0.23 1.02394322E8 3340000.0 0.29 0.3659 0.9917 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I23 compound treatment 9.4392269E7 -4450000.0 -0.38 1.09106934E8 1.01E7 0.88 0.3501 0.3647 3188402 PK04_108179 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 I24 compound treatment 8.1804962E7 -1.7E7 -1.47 8.484741E7 -1.42E7 -1.24 -1.9199 -0.9965 3071774 PK04_108180 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J01 compound treatment 1.11570994E8 1.27E7 1.1 1.06157535E8 7100000.0 0.62 1.2168 0.9636 3188403 PK04_108181 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J02 compound treatment 1.07119116E8 8270000.0 0.71 1.03875625E8 4820000.0 0.42 0.8037 0.9684 3071776 PK04_108182 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J03 compound treatment 1.04443934E8 5600000.0 0.48 1.0333123E8 4280000.0 0.37 0.6066 0.992 3188404 PK04_108183 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J04 compound treatment 9.5828282E7 -3020000.0 -0.26 9.6979477E7 -2080000.0 -0.18 -0.3127 -0.9845 3188405 PK04_108184 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J05 mock treatment 1.04356439E8 5510000.0 0.48 1.00735417E8 1680000.0 0.15 0.4406 0.8843 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J06 mock treatment 9.643748E7 -2410000.0 -0.21 9.5848569E7 -3210000.0 -0.28 -0.3454 -0.9891 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J07 compound treatment 9.3523578E7 -5320000.0 -0.46 9.2404693E7 -6650000.0 -0.58 -0.7365 -0.9932 3070928 PK04_108185 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J08 compound treatment 9.3954436E7 -4890000.0 -0.42 9.6780433E7 -2270000.0 -0.2 -0.4394 -0.9411 3070929 PK04_108186 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J09 compound treatment 1.00197189E8 1350000.0 0.12 1.00474297E8 1420000.0 0.12 0.1704 0.9995 3070930 PK04_108187 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J10 compound treatment 9.2924375E7 -5920000.0 -0.51 9.3987126E7 -5070000.0 -0.44 -0.6752 -0.9975 3188406 PK04_108188 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J11 compound treatment 9.7207963E7 -1640000.0 -0.14 1.0035569E8 1300000.0 0.11 -0.0195 -0.1072 3188407 PK04_108189 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J12 compound treatment 9.210422E7 -6740000.0 -0.58 9.608318E7 -2970000.0 -0.26 -0.5956 -0.934 3070931 PK04_108190 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J13 compound treatment 1.00893059E8 2050000.0 0.18 1.0282619E8 3770000.0 0.33 0.3585 0.9573 3070932 PK04_108191 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J14 compound treatment 9.6399732E7 -2440000.0 -0.21 9.7794862E7 -1260000.0 -0.11 -0.2273 -0.9541 3070933 PK04_108192 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J15 compound treatment 1.03362744E8 4520000.0 0.39 1.0542494E8 6370000.0 0.56 0.6701 0.9848 3188522 PK04_108193 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J16 compound treatment 9.1396006E7 -7450000.0 -0.64 9.8203654E7 -851000.0 -0.07 -0.5076 -0.7838 3188523 PK04_108194 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J17 compound treatment 9.8735352E7 -109000.0 -0.01 1.05053621E8 6000000.0 0.52 0.3645 0.6943 3070934 PK04_108195 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J18 compound treatment 9.2862615E7 -5980000.0 -0.52 9.6906547E7 -2150000.0 -0.19 -0.4983 -0.9063 3188524 PK04_108196 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J19 compound treatment 1.02096689E8 3250000.0 0.28 1.0443794E8 5380000.0 0.47 0.5317 0.9695 3070935 PK04_108197 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J20 compound treatment 9.6030588E7 -2810000.0 -0.24 9.8975415E7 -79500.0 -0.01 -0.1768 -0.7271 3188525 PK04_108198 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J21 mock treatment 1.02980261E8 4140000.0 0.36 1.07433213E8 8380000.0 0.73 0.7711 0.9454 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J22 mock treatment 9.9041271E7 197000.0 0.02 1.01360379E8 2310000.0 0.2 0.1547 0.7639 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J23 compound treatment 8.9563003E7 -9280000.0 -0.8 1.05667072E8 6610000.0 0.58 -0.1577 -0.1595 3070936 PK04_108199 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 J24 compound treatment 8.5830002E7 -1.3E7 -1.12 9.682035E7 -2230000.0 -0.2 -0.9331 -0.8178 3188526 PK04_108200 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K01 compound treatment 1.06057359E8 7210000.0 0.62 1.02575465E8 3520000.0 0.31 0.6584 0.9473 3070937 PK04_108201 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K02 compound treatment 9.8816521E7 -28200.0 0.0 9.0362396E7 -8690000.0 -0.76 -0.5397 -0.7094 3188527 PK04_108202 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K03 compound treatment 1.04430395E8 5590000.0 0.48 9.8435426E7 -619000.0 -0.05 0.3028 0.6237 3188528 PK04_108203 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K04 compound treatment 9.5617005E7 -3230000.0 -0.28 9.1692577E7 -7360000.0 -0.64 -0.6527 -0.9298 3070938 PK04_108204 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K05 compound treatment 1.00907313E8 2060000.0 0.18 1.04906155E8 5850000.0 0.51 0.4881 0.9002 3188529 PK04_108205 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K06 compound treatment 6.8238703E7 -3.06E7 -2.64 7.6427356E7 -2.26E7 -1.98 -3.2695 -0.9899 3070939 PK04_108206 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K07 mock treatment 1.02711854E8 3870000.0 0.33 9.8477866E7 -577000.0 -0.05 0.2005 0.5935 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K08 mock treatment 8.9681111E7 -9160000.0 -0.79 9.875083E7 -304000.0 -0.03 -0.5785 -0.7305 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K09 compound treatment 1.11824743E8 1.3E7 1.12 1.08933984E8 9880000.0 0.86 1.4041 0.9918 3188530 PK04_108207 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K10 compound treatment 9.3485186E7 -5360000.0 -0.46 9.4209088E7 -4850000.0 -0.42 -0.6272 -0.999 3188531 PK04_108208 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K11 compound treatment 7.9996565E7 -1.88E7 -1.63 6.9061032E7 -3.0E7 -2.62 -3.0073 -0.9736 3070940 PK04_108209 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K12 compound treatment 9.1626312E7 -7220000.0 -0.62 9.7624057E7 -1430000.0 -0.13 -0.5294 -0.8325 3188532 PK04_108210 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K13 compound treatment 9.5389107E7 -3460000.0 -0.3 1.05930256E8 6880000.0 0.6 0.2144 0.3192 3188533 PK04_108211 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K14 compound treatment 9.1687928E7 -7160000.0 -0.62 9.0834705E7 -8220000.0 -0.72 -0.9458 -0.9971 3070941 PK04_108212 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K15 mock treatment 1.04083032E8 5240000.0 0.45 8.2238529E7 -1.68E7 -1.47 -0.7207 -0.4681 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K16 mock treatment 9.5247191E7 -3600000.0 -0.31 9.5164753E7 -3890000.0 -0.34 -0.4605 -0.999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K17 compound treatment 1.02929279E8 4080000.0 0.35 1.04906443E8 5850000.0 0.51 0.6116 0.9835 3188534 PK04_108213 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K18 compound treatment 9.9483538E7 639000.0 0.06 9.5484117E7 -3570000.0 -0.31 -0.182 -0.5734 3070942 PK04_108214 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K19 compound treatment 1.04291052E8 5450000.0 0.47 1.0795694E8 8900000.0 0.78 0.8835 0.9708 3188535 PK04_108215 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K20 compound treatment 1.03348948E8 4500000.0 0.39 1.0356832E8 4510000.0 0.4 0.5544 1.0 3070943 PK04_108216 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K21 compound treatment 1.13801637E8 1.5E7 1.29 1.09570862E8 1.05E7 0.92 1.5643 0.9862 3188536 PK04_108217 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K22 compound treatment 1.04685958E8 5840000.0 0.5 1.03164592E8 4110000.0 0.36 0.6111 0.9862 3188537 PK04_108218 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K23 mock treatment 1.0734988E8 8510000.0 0.73 1.05208829E8 6150000.0 0.54 0.9003 0.9884 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 K24 mock treatment 9.9234097E7 389000.0 0.03 1.02996654E8 3940000.0 0.34 0.2677 0.7724 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L01 compound treatment 1.0114784E8 2300000.0 0.2 1.06957615E8 7900000.0 0.69 0.6297 0.875 3070944 PK04_108219 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L02 compound treatment 9.7012444E7 -1830000.0 -0.16 9.3743263E7 -5310000.0 -0.46 -0.4406 -0.8973 3188538 PK04_108220 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L03 compound treatment 1.09078786E8 1.02E7 0.88 1.04501436E8 5450000.0 0.48 0.9621 0.958 3188539 PK04_108221 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L04 compound treatment 9.6547876E7 -2300000.0 -0.2 9.7645447E7 -1410000.0 -0.12 -0.2275 -0.9739 3215882 PK04_108222 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L05 compound treatment 1.03388315E8 4540000.0 0.39 1.06123232E8 7070000.0 0.62 0.7149 0.9759 3188540 PK04_108223 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L06 compound treatment 9.8616542E7 -228000.0 -0.02 9.8249448E7 -805000.0 -0.07 -0.0638 -0.8714 3215880 PK04_108224 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L07 mock treatment 1.04634262E8 5790000.0 0.5 9.622459E7 -2830000.0 -0.25 0.1784 0.3198 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L08 mock treatment 9.6834681E7 -2010000.0 -0.17 9.6904463E7 -2150000.0 -0.19 -0.2558 -0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L09 compound treatment 9.7209905E7 -1630000.0 -0.14 1.00326795E8 1270000.0 0.11 -0.0211 -0.1175 3188541 PK04_108225 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L10 compound treatment 9.0031878E7 -8810000.0 -0.76 9.0566377E7 -8490000.0 -0.74 -1.0635 -0.9999 3188542 PK04_108226 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L11 compound treatment 9.0368455E7 -8480000.0 -0.73 9.0687025E7 -8370000.0 -0.73 -1.0355 -1.0 3070947 PK04_108227 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L12 compound treatment 9.0309931E7 -8530000.0 -0.74 9.137016E7 -7680000.0 -0.67 -0.9968 -0.999 3188543 PK04_108228 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L13 compound treatment 1.01003211E8 2160000.0 0.19 9.2674652E7 -6380000.0 -0.56 -0.263 -0.4468 3188544 PK04_108229 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L14 compound treatment 8.8547348E7 -1.03E7 -0.89 9.3532516E7 -5520000.0 -0.48 -0.9707 -0.9589 3070948 PK04_108230 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L15 mock treatment 9.6385859E7 -2460000.0 -0.21 8.5495393E7 -1.36E7 -1.19 -0.9893 -0.8206 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L16 mock treatment 9.9368318E7 524000.0 0.05 9.6334008E7 -2720000.0 -0.24 -0.1364 -0.5627 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L17 compound treatment 9.8219117E7 -626000.0 -0.05 1.06667483E8 7610000.0 0.67 0.4329 0.6476 3188657 PK04_108231 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L18 compound treatment 9.1254296E7 -7590000.0 -0.66 9.0390714E7 -8660000.0 -0.76 -0.9998 -0.9974 3070949 PK04_108232 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L19 compound treatment 1.02991015E8 4150000.0 0.36 1.05500515E8 6450000.0 0.56 0.6521 0.976 3188658 PK04_108233 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L20 compound treatment 9.6985699E7 -1860000.0 -0.16 9.7613805E7 -1440000.0 -0.13 -0.2027 -0.9929 3070950 PK04_108234 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L21 compound treatment 1.07063558E8 8220000.0 0.71 1.06543073E8 7490000.0 0.66 0.9654 0.9992 3188659 PK04_108235 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L22 compound treatment 9.5242157E7 -3600000.0 -0.31 9.7994596E7 -1060000.0 -0.09 -0.2856 -0.8797 3070951 PK04_108236 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L23 mock treatment 1.07311597E8 8470000.0 0.73 1.09449396E8 1.04E7 0.91 1.1604 0.9941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 L24 mock treatment 1.05621722E8 6780000.0 0.59 1.01732835E8 2680000.0 0.23 0.5796 0.9193 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M01 compound treatment 1.07741366E8 8900000.0 0.77 1.09602601E8 1.05E7 0.92 1.1961 0.9958 3188660 PK04_108237 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M02 compound treatment 8.9147098E7 -9700000.0 -0.84 8.4496771E7 -1.46E7 -1.27 -1.4932 -0.9793 3070952 PK04_108238 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M03 compound treatment 1.13848167E8 1.5E7 1.3 1.09924538E8 1.09E7 0.95 1.589 0.9884 3188661 PK04_108239 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M04 compound treatment 8.84193E7 -1.04E7 -0.9 8.1312043E7 -1.77E7 -1.55 -1.7347 -0.9664 3070953 PK04_108240 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M05 compound treatment 7.9387951E7 -1.95E7 -1.68 8.2097716E7 -1.7E7 -1.48 -2.2377 -0.9981 3188662 PK04_108241 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M06 compound treatment 9.7783001E7 -1060000.0 -0.09 9.7185371E7 -1870000.0 -0.16 -0.1805 -0.9625 3070954 PK04_108242 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M07 compound treatment 9.3387915E7 -5460000.0 -0.47 1.01277654E8 2220000.0 0.19 -0.1957 -0.3838 3188663 PK04_108243 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M08 compound treatment 2.228688E7 -7.66E7 -6.61 2.3047395E7 -7.6E7 -6.65 -9.3794 -1.0 3188664 PK04_108244 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M09 mock treatment 9.448865E7 -4360000.0 -0.38 1.01984007E8 2930000.0 0.26 -0.0848 -0.1862 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M10 mock treatment 9.1543296E7 -7300000.0 -0.63 1.00661306E8 1610000.0 0.14 -0.3465 -0.5363 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M11 compound treatment 9.8071554E7 -773000.0 -0.07 9.4646743E7 -4410000.0 -0.39 -0.32 -0.8173 3070955 PK04_108245 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M12 compound treatment 8.5359683E7 -1.35E7 -1.16 7.8652776E7 -2.04E7 -1.79 -2.0862 -0.9786 3188665 PK04_108246 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M13 mock treatment 9.9803391E7 959000.0 0.08 1.03994101E8 4940000.0 0.43 0.3642 0.8275 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M14 mock treatment 9.7807023E7 -1040000.0 -0.09 9.7518784E7 -1540000.0 -0.13 -0.1584 -0.9806 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M15 compound treatment 9.1976541E7 -6870000.0 -0.59 8.8600223E7 -1.05E7 -0.91 -1.0664 -0.978 3188666 PK04_108247 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M16 compound treatment 8.6256725E7 -1.26E7 -1.09 9.3667206E7 -5390000.0 -0.47 -1.1022 -0.9301 3070994 PK04_108248 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M17 compound treatment 1.06555966E8 7710000.0 0.67 1.09851423E8 1.08E7 0.94 1.1391 0.9853 3188667 PK04_108249 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M18 compound treatment 9.7192964E7 -1650000.0 -0.14 9.1248792E7 -7810000.0 -0.68 -0.584 -0.8367 3070995 PK04_108250 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M19 compound treatment 1.00336544E8 1490000.0 0.13 1.09744669E8 1.07E7 0.94 0.7526 0.797 3188668 PK04_108251 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M20 compound treatment 9.5905118E7 -2940000.0 -0.25 1.03040719E8 3990000.0 0.35 0.0671 0.1556 2133134 PK04_108252 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M21 compound treatment 8.9811673E7 -9030000.0 -0.78 1.02973552E8 3920000.0 0.34 -0.3092 -0.3628 3070996 PK04_108253 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M22 compound treatment 9.6419384E7 -2430000.0 -0.21 9.8186405E7 -869000.0 -0.08 -0.2019 -0.9059 2133147 PK04_108254 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M23 compound treatment 9.7843689E7 -1000000.0 -0.09 1.0939805E8 1.03E7 0.91 0.5789 0.6367 3070997 PK04_108255 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 M24 compound treatment 1.06309716E8 7470000.0 0.64 9.526548E7 -3790000.0 -0.33 0.2214 0.3054 3188671 PK04_108256 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N01 compound treatment 1.14101364E8 1.53E7 1.32 1.09792425E8 1.07E7 0.94 1.5963 0.9863 3188672 PK04_108257 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N02 compound treatment 9.5390308E7 -3450000.0 -0.3 1.05200885E8 6150000.0 0.54 0.1694 0.2753 3070998 PK04_108258 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N03 compound treatment 1.10733445E8 1.19E7 1.03 9.8421642E7 -633000.0 -0.06 0.6869 0.668 3188673 PK04_108259 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N04 compound treatment 1.04254591E8 5410000.0 0.47 9.512281E7 -3930000.0 -0.34 0.0871 0.15 3070999 PK04_108260 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N05 compound treatment 9.8585989E7 -259000.0 -0.02 1.07672675E8 8620000.0 0.75 0.5175 0.6859 3188674 PK04_108261 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N06 compound treatment 9.7563535E7 -1280000.0 -0.11 9.0998186E7 -8060000.0 -0.71 -0.5768 -0.8082 3071000 PK04_108262 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N07 compound treatment 1.03084706E8 4240000.0 0.37 1.06999674E8 7940000.0 0.7 0.7506 0.9552 3188675 PK04_108263 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N08 compound treatment 8.9526207E7 -9320000.0 -0.8 1.02972046E8 3920000.0 0.34 -0.3267 -0.3735 3188676 PK04_108264 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N09 mock treatment 1.0399342E8 5150000.0 0.44 9.7770947E7 -1280000.0 -0.11 0.235 0.5123 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N10 mock treatment 9.7897884E7 -947000.0 -0.08 9.8946742E7 -108000.0 -0.01 -0.0645 -0.7837 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N11 compound treatment 9.3720924E7 -5120000.0 -0.44 9.4640668E7 -4410000.0 -0.39 -0.5861 -0.9977 3071001 PK04_108265 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N12 compound treatment 9.6740028E7 -2100000.0 -0.18 7.5042253E7 -2.4E7 -2.1 -1.6145 -0.7654 3188677 PK04_108266 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N13 mock treatment 1.02344914E8 3500000.0 0.3 1.05668398E8 6610000.0 0.58 0.623 0.9541 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N14 mock treatment 8.6152396E7 -1.27E7 -1.1 1.01132461E8 2080000.0 0.18 -0.6466 -0.5819 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N15 compound treatment 8.7076979E7 -1.18E7 -1.02 9.6932195E7 -2120000.0 -0.19 -0.8501 -0.8227 3071002 PK04_108267 OCC1CC(=NO1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N16 compound treatment 9.2414233E7 -6430000.0 -0.56 9.1558045E7 -7500000.0 -0.66 -0.8567 -0.9966 3188788 PK04_108268 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N17 compound treatment 9.9671078E7 826000.0 0.07 1.03484951E8 4430000.0 0.39 0.3246 0.8234 3071004 PK04_108269 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N18 compound treatment 9.1001081E7 -7840000.0 -0.68 1.00621775E8 1570000.0 0.14 -0.3821 -0.5528 3071005 PK04_108270 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N19 compound treatment 1.03542629E8 4700000.0 0.41 9.6500471E7 -2550000.0 -0.22 0.1288 0.2781 3414065 PK04_108271 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N20 compound treatment 1.00392477E8 1550000.0 0.13 1.01470944E8 2420000.0 0.21 0.244 0.9755 3188790 PK04_108272 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N21 compound treatment 9.7928443E7 -916000.0 -0.08 1.01539228E8 2480000.0 0.22 0.0978 0.4226 3071008 PK04_108273 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N22 compound treatment 1.00499488E8 1650000.0 0.14 9.7782357E7 -1270000.0 -0.11 0.0223 0.1232 3188791 PK04_108274 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N23 compound treatment 9.6775244E7 -2070000.0 -0.18 1.06431123E8 7380000.0 0.65 0.3301 0.4928 3188792 PK04_108275 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 N24 compound treatment 1.07434253E8 8590000.0 0.74 1.06531049E8 7480000.0 0.65 0.9873 0.998 3188793 PK04_108276 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O01 compound treatment 1.19652878E8 2.08E7 1.8 1.09660404E8 1.06E7 0.93 1.9272 0.9527 3071055 PK04_108277 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O02 compound treatment 9.7952361E7 -892000.0 -0.08 9.6372366E7 -2680000.0 -0.23 -0.2205 -0.8924 2129060 PK04_108278 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O03 compound treatment 8.5515304E7 -1.33E7 -1.15 9.2490354E7 -6560000.0 -0.57 -1.2203 -0.9484 3188794 PK04_108279 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O04 compound treatment 9.2526698E7 -6320000.0 -0.55 1.00567285E8 1510000.0 0.13 -0.2923 -0.5205 2129057 PK04_108280 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O05 compound treatment 1.14615043E8 1.58E7 1.36 1.09467597E8 1.04E7 0.91 1.6075 0.9809 3188796 PK04_108281 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O06 compound treatment 1.01287698E8 2440000.0 0.21 9.8501977E7 -553000.0 -0.05 0.115 0.5312 2129061 PK04_108282 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O07 compound treatment 1.00235852E8 1390000.0 0.12 9.9604951E7 550000.0 0.05 0.119 0.9194 3071060 PK04_108283 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O08 compound treatment 9.8362066E7 -483000.0 -0.04 9.5771254E7 -3280000.0 -0.29 -0.2327 -0.8013 2129067 PK04_108284 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O09 compound treatment 9.2275354E7 -6570000.0 -0.57 9.4455559E7 -4600000.0 -0.4 -0.6858 -0.9859 3188797 PK04_108285 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O10 compound treatment 8.855022E7 -1.03E7 -0.89 8.8338059E7 -1.07E7 -0.94 -1.2919 -0.9996 2129068 PK04_108286 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O11 mock treatment 1.00631402E8 1790000.0 0.15 1.01668315E8 2610000.0 0.23 0.2709 0.9817 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O12 mock treatment 9.5323808E7 -3520000.0 -0.3 9.5236264E7 -3820000.0 -0.33 -0.4514 -0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O13 compound treatment 1.03569394E8 4720000.0 0.41 1.07828841E8 8770000.0 0.77 0.8315 0.9562 3188798 PK04_108287 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O14 compound treatment 9.5424603E7 -3420000.0 -0.3 9.9587348E7 532000.0 0.05 -0.1759 -0.5883 3071064 PK04_108288 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O15 compound treatment 1.00150922E8 1310000.0 0.11 9.8993737E7 -61200.0 -0.01 0.076 0.6728 3188799 PK04_108289 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O16 compound treatment 9.4686163E7 -4160000.0 -0.36 9.7873389E7 -1180000.0 -0.1 -0.3271 -0.8751 2133032 PK04_108290 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O17 compound treatment 1.0764768E8 8800000.0 0.76 1.07280047E8 8230000.0 0.72 1.0466 0.9996 3071066 PK04_108291 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O18 compound treatment 9.9213567E7 369000.0 0.03 1.03669393E8 4610000.0 0.4 0.3081 0.7605 2133035 PK04_108292 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O19 compound treatment 1.04849302E8 6000000.0 0.52 1.06152334E8 7100000.0 0.62 0.8059 0.996 3071068 PK04_108293 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O20 compound treatment 1.02262788E8 3420000.0 0.3 1.06910456E8 7860000.0 0.69 0.6949 0.9287 2133267 PK04_108294 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O21 compound treatment 9.8374398E7 -470000.0 -0.04 9.7160717E7 -1890000.0 -0.17 -0.1459 -0.8551 3071112 PK04_108295 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O22 compound treatment 1.04269504E8 5420000.0 0.47 1.07429038E8 8370000.0 0.73 0.8495 0.9766 2133153 PK04_108296 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O23 compound treatment 9.8800123E7 -44600.0 0.0 1.05545734E8 6490000.0 0.57 0.399 0.7023 3188804 PK04_108297 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 O24 compound treatment 1.07241926E8 8400000.0 0.73 1.08296744E8 9240000.0 0.81 1.0848 0.9985 2132929 PK04_108298 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P01 compound treatment 9.8363697E7 -481000.0 -0.04 1.00514215E8 1460000.0 0.13 0.0609 0.4537 3188805 PK04_108299 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P02 compound treatment 9.0663334E7 -8180000.0 -0.71 1.02863115E8 3810000.0 0.33 -0.264 -0.3379 3071118 PK04_108300 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P03 compound treatment 1.0764219E8 8800000.0 0.76 9.6044391E7 -3010000.0 -0.26 0.351 0.4364 3188806 PK04_108301 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P04 compound treatment 9.9853298E7 1010000.0 0.09 1.00441798E8 1390000.0 0.12 0.1474 0.9868 3071120 PK04_108302 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P05 compound treatment 1.06962304E8 8120000.0 0.7 1.05146819E8 6090000.0 0.53 0.8728 0.9909 3188807 PK04_108303 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P06 compound treatment 1.00429061E8 1580000.0 0.14 1.00703359E8 1650000.0 0.14 0.1988 0.9997 3188808 PK04_108304 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P07 compound treatment 1.03853607E8 5010000.0 0.43 1.05378303E8 6320000.0 0.55 0.6972 0.9926 3071124 PK04_108305 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P08 compound treatment 1.00307034E8 1460000.0 0.13 9.832886E7 -726000.0 -0.06 0.0444 0.3139 3188923 PK04_108306 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P09 compound treatment 9.8502427E7 -342000.0 -0.03 1.04965248E8 5910000.0 0.52 0.3449 0.6656 3188924 PK04_108307 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P10 compound treatment 8.7061278E7 -1.18E7 -1.02 9.7277581E7 -1780000.0 -0.16 -0.8297 -0.8058 3071127 PK04_108308 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P11 mock treatment 1.00268652E8 1420000.0 0.12 1.01541615E8 2490000.0 0.22 0.2409 0.9635 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P12 mock treatment 9.786706E7 -978000.0 -0.08 1.01495409E8 2440000.0 0.21 0.0913 0.3976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P13 compound treatment 1.00184703E8 1340000.0 0.12 1.05285945E8 6230000.0 0.55 0.4674 0.8385 3188925 PK04_108309 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P14 compound treatment 9.6114117E7 -2730000.0 -0.24 1.01317377E8 2260000.0 0.2 -0.0268 -0.0869 3071425 PK04_108310 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P15 compound treatment 9.5829575E7 -3020000.0 -0.26 1.04854965E8 5800000.0 0.51 0.1748 0.3064 3188926 PK04_108311 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P16 compound treatment 9.9694245E7 850000.0 0.07 9.7766967E7 -1290000.0 -0.11 -0.0278 -0.2068 3215868 PK04_108312 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P17 compound treatment 1.13323446E8 1.45E7 1.25 1.09786977E8 1.07E7 0.94 1.5484 0.99 3188927 PK04_108313 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P18 compound treatment 9.6150863E7 -2690000.0 -0.23 1.01856258E8 2800000.0 0.25 0.0088 0.0261 3215866 PK04_108314 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P19 compound treatment 1.12104217E8 1.33E7 1.15 1.08734606E8 9680000.0 0.85 1.4088 0.989 3071435 PK04_108315 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P20 compound treatment 1.02277703E8 3430000.0 0.3 1.03842827E8 4790000.0 0.42 0.506 0.9857 3071437 PK04_108316 OB1OC(CCc2ccccc2)CC=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P21 compound treatment 1.03406613E8 4560000.0 0.39 1.09309837E8 1.03E7 0.9 0.9132 0.9317 3188929 PK04_108317 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P22 compound treatment 1.00997535E8 2150000.0 0.19 1.05229403E8 6170000.0 0.54 0.5136 0.8987 3071483 PK04_108318 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P23 compound treatment 1.19235182E8 2.04E7 1.76 1.09770194E8 1.07E7 0.94 1.9084 0.9565 3188930 PK04_108319 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2108 P24 compound treatment 1.08358976E8 9510000.0 0.82 1.08096655E8 9040000.0 0.79 1.1406 0.9998 3071486 PK04_108320 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A01 compound treatment 1.08151439E8 9980000.0 0.86 1.02228977E8 8280000.0 0.72 1.122 0.9963 3131442 CMLD2_000001 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A02 compound treatment 1.08584415E8 1.04E7 0.9 1.04184906E8 1.02E7 0.9 1.2695 1.0 3131443 CMLD2_000002 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A03 compound treatment 1.03403727E8 5230000.0 0.45 1.01843121E8 7890000.0 0.69 0.8082 0.9789 3010137 CMLD2_000003 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A04 compound treatment 1.03655969E8 5490000.0 0.47 9.1399316E7 -2550000.0 -0.22 0.1773 0.3385 3131444 CMLD2_000004 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A05 compound treatment 9.5675021E7 -2500000.0 -0.22 1.03021518E8 9070000.0 0.79 0.4091 0.4972 3131445 CMLD2_000005 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A06 compound treatment 1.06083896E8 7910000.0 0.68 1.0317087E8 9220000.0 0.81 1.054 0.9966 3010139 CMLD2_000006 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A07 compound treatment 1.09216545E8 1.1E7 0.95 1.01133963E8 7190000.0 0.63 1.1193 0.9795 3131446 CMLD2_000007 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A08 compound treatment 1.00465293E8 2300000.0 0.2 9.1515645E7 -2430000.0 -0.21 -0.0104 -0.0357 3010141 CMLD2_000008 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A09 compound treatment 9.111665E7 -7050000.0 -0.61 1.01322459E8 7370000.0 0.65 0.0255 0.0288 3010141 CMLD2_000009 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A10 compound treatment 1.01107203E8 2940000.0 0.25 9.7610553E7 3660000.0 0.32 0.406 0.9933 3010142 CMLD2_000010 CC(C)[C@H](O)C1=CCCCC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A11 compound treatment 9.7915718E7 -254000.0 -0.02 9.564599E7 1700000.0 0.15 0.0895 0.596 3131447 CMLD2_000011 O=C(OCc1ccccc1)C(C2CCCC(=O)C2)C(=O)OCc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A12 compound treatment 9.6708078E7 -1460000.0 -0.13 9.4613746E7 665000.0 0.06 -0.0481 -0.3462 3010143 CMLD2_000012 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A13 mock treatment 9.1837135E7 -6330000.0 -0.55 8.9143514E7 -4810000.0 -0.42 -0.6841 -0.9916 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A14 mock treatment 9.9760525E7 1590000.0 0.14 9.5864468E7 1920000.0 0.17 0.2157 0.9951 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A15 compound treatment 1.0187264E8 3700000.0 0.32 9.8063262E7 4110000.0 0.36 0.4808 0.9982 3131448 CMLD2_000013 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A16 compound treatment 9.9228958E7 1060000.0 0.09 9.3564989E7 -384000.0 -0.03 0.0409 0.4201 3131449 CMLD2_000014 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A17 compound treatment 9.5210838E7 -2960000.0 -0.26 9.0753083E7 -3200000.0 -0.28 -0.3785 -0.999 3010159 CMLD2_000015 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A18 mock treatment 1.01705593E8 3540000.0 0.31 9.9096748E7 5150000.0 0.45 0.5345 0.9821 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A19 compound treatment 1.05521149E8 7350000.0 0.63 1.02773326E8 8820000.0 0.77 0.9951 0.9953 3131450 CMLD2_000016 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A20 compound treatment 1.01617346E8 3450000.0 0.3 9.8730548E7 4780000.0 0.42 0.5065 0.9861 3010162 CMLD2_000017 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A21 compound treatment 9.7320757E7 -849000.0 -0.07 9.3828164E7 -120000.0 -0.01 -0.0593 -0.8005 3131451 CMLD2_000018 COc1ccc(OC[C@H]2Cc3c(nc4CCN(CCOc5ccccc5)Cc4c3CO2)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A22 compound treatment 1.05230524E8 7060000.0 0.61 1.0446365E8 1.05E7 0.92 1.0819 0.98 3131452 CMLD2_000019 COC(=O)C1=C(C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A23 compound treatment 1.05950544E8 7780000.0 0.67 1.02027325E8 8080000.0 0.71 0.9751 0.9997 3010166 CMLD2_000020 COc1cccc(c1)[C@H]2N[C@@H](CC[C@@H]2C)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 A24 compound treatment 1.08895609E8 1.07E7 0.93 1.06467451E8 1.25E7 1.1 1.4298 0.9965 3010168 CMLD2_000021 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)C)c3ccccc3)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B01 compound treatment 1.08779837E8 1.06E7 0.92 1.06276521E8 1.23E7 1.08 1.4109 0.9967 3131453 CMLD2_000022 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B02 compound treatment 1.05743822E8 7570000.0 0.65 9.9814477E7 5870000.0 0.51 0.8256 0.9928 3131569 CMLD2_000023 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B03 compound treatment 1.07612898E8 9440000.0 0.82 9.7751046E7 3800000.0 0.33 0.812 0.9218 3131570 CMLD2_000024 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B04 compound treatment 9.3278682E7 -4890000.0 -0.42 8.7752698E7 -6200000.0 -0.54 -0.6822 -0.9924 3010172 CMLD2_000025 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B05 compound treatment 1.01416215E8 3250000.0 0.28 9.398228E7 33600.0 0.0 0.2003 0.7145 3131571 CMLD2_000026 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B06 compound treatment 1.05697779E8 7530000.0 0.65 1.0188072E8 7930000.0 0.69 0.9506 0.9995 3010200 CMLD2_000027 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B07 compound treatment 1.00956558E8 2790000.0 0.24 1.01528337E8 7580000.0 0.66 0.6392 0.9059 3131572 CMLD2_000028 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B08 compound treatment 8.8131868E7 -1.0E7 -0.87 8.8365592E7 -5580000.0 -0.49 -0.9586 -0.9632 3010203 CMLD2_000029 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B09 compound treatment 9.7437637E7 -733000.0 -0.06 9.5406707E7 1460000.0 0.13 0.0455 0.3194 3010205 CMLD2_000030 COC(=O)NC/C=C\c1nc(CC/C=C\C(=O)OC)co1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B10 compound treatment 1.00932504E8 2760000.0 0.24 9.3910521E7 -38100.0 0.0 0.1663 0.6971 3131573 CMLD2_000031 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@H](O)c2c(=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B11 compound treatment 1.04007706E8 5840000.0 0.5 9.8933465E7 4980000.0 0.44 0.665 0.9974 3010207 CMLD2_000032 CC1(C)OCC(CO1)C(O)C2=CCCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B12 compound treatment 9.0454534E7 -7720000.0 -0.67 8.3028315E7 -1.09E7 -0.96 -1.147 -0.9845 3131574 CMLD2_000033 COC(=O)[C@H](C)NC(=O)[C@@H](C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B13 mock treatment 9.9260692E7 1090000.0 0.09 9.680134E7 2850000.0 0.25 0.2431 0.9112 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B14 mock treatment 9.8239898E7 69700.0 0.01 9.1497858E7 -2450000.0 -0.21 -0.1474 -0.687 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B15 compound treatment 1.01159763E8 2990000.0 0.26 9.6671871E7 2720000.0 0.24 0.3511 0.9992 3010209 CMLD2_000034 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B16 compound treatment 9.1158183E7 -7010000.0 -0.61 8.2466894E7 -1.15E7 -1.0 -1.1388 -0.9706 2082484 CMLD2_000035 COC(=O)C(C1CCCC(=O)C1)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B17 compound treatment 1.01411085E8 3240000.0 0.28 9.5770777E7 1820000.0 0.16 0.3107 0.9644 3131575 CMLD2_000036 COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B18 mock treatment 1.01436203E8 3270000.0 0.28 9.7961919E7 4010000.0 0.35 0.4478 0.9941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B19 compound treatment 1.0356478E8 5390000.0 0.47 1.02213624E8 8260000.0 0.72 0.8409 0.9774 3010212 CMLD2_000037 CO[C@@H]1[C@H](O)CO[C@H]1/C=C/c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B20 compound treatment 9.1034341E7 -7140000.0 -0.62 9.023634E7 -3710000.0 -0.32 -0.6656 -0.9553 3131576 CMLD2_000038 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B21 compound treatment 1.08682522E8 1.05E7 0.91 1.03054653E8 9110000.0 0.8 1.2056 0.9979 3010215 CMLD2_000039 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B22 compound treatment 1.05714177E8 7540000.0 0.65 1.00327667E8 6380000.0 0.56 0.8555 0.997 3131577 CMLD2_000040 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B23 compound treatment 1.08874753E8 1.07E7 0.92 1.05506519E8 1.16E7 1.01 1.369 0.999 3010186 CMLD2_000041 COc1ccc(cc1)c2ccccc2[C@@H]3N[C@@H](CC[C@H]3C)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 B24 compound treatment 9.8565855E7 396000.0 0.03 9.3396938E7 -552000.0 -0.05 -0.01 -0.1686 3131578 CMLD2_000042 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCOC4=O)C(=O)CC)c5ccccc5)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C01 compound treatment 1.08650885E8 1.05E7 0.91 9.8525222E7 4580000.0 0.4 0.9233 0.9327 3131579 CMLD2_000043 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7ccccc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C02 compound treatment 1.06418892E8 8250000.0 0.71 1.0481486E8 1.09E7 0.95 1.1762 0.9899 3010248 CMLD2_000044 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C03 compound treatment 1.02830398E8 4660000.0 0.4 9.9442856E7 5490000.0 0.48 0.6246 0.9961 3131580 CMLD2_000045 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C04 compound treatment 9.2469458E7 -5700000.0 -0.49 9.8377378E7 4430000.0 0.39 -0.0741 -0.1183 3131581 CMLD2_000046 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3ccc4OCOc4c3)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C05 compound treatment 1.02487882E8 4320000.0 0.37 8.4119138E7 -9830000.0 -0.86 -0.3446 -0.3675 3131582 CMLD2_000047 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C06 compound treatment 9.94223E7 1250000.0 0.11 9.5605283E7 1660000.0 0.14 0.179 0.9896 3010252 CMLD2_000048 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C07 compound treatment 1.01916064E8 3750000.0 0.32 9.6304088E7 2360000.0 0.21 0.3745 0.9763 3131583 CMLD2_000049 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C08 compound treatment 9.0450908E7 -7720000.0 -0.67 9.1158122E7 -2790000.0 -0.24 -0.6441 -0.9072 3010254 CMLD2_000050 Cc1cc2N(CC(O)CN3CCCc4nc(C)c(C)cc34)CCCc2nc1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C09 compound treatment 9.7913919E7 -256000.0 -0.02 8.4736967E7 -9210000.0 -0.81 -0.5857 -0.7262 3131584 CMLD2_000051 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C10 compound treatment 8.9025312E7 -9140000.0 -0.79 8.3670251E7 -1.03E7 -0.9 -1.1946 -0.9979 3010257 CMLD2_000052 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@@H](O)c2c(=O)o1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C11 mock treatment 9.8019687E7 -150000.0 -0.01 9.4957452E7 1010000.0 0.09 0.0532 0.5966 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C12 mock treatment 9.0045602E7 -8120000.0 -0.7 9.2391721E7 -1560000.0 -0.14 -0.5926 -0.8289 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C13 compound treatment 9.8459972E7 290000.0 0.03 8.6707915E7 -7240000.0 -0.63 -0.4304 -0.6786 3010259 CMLD2_000053 OC(CCOCc1ccccc1)C2=CCCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C14 compound treatment 9.7152309E7 -1020000.0 -0.09 9.3267196E7 -681000.0 -0.06 -0.1043 -0.9821 1304363 CMLD2_000054 C1Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C15 mock treatment 9.8177133E7 6970.0 0.0 9.5775798E7 1830000.0 0.16 0.1135 0.7098 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C16 mock treatment 8.9087527E7 -9080000.0 -0.78 9.4312542E7 364000.0 0.03 -0.5322 -0.6778 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C17 compound treatment 9.3527679E7 -4640000.0 -0.4 8.4133473E7 -9820000.0 -0.86 -0.8909 -0.9398 3010233 CMLD2_000055 COc1ccc(cc1)c2cnnc(CCCn3ccnc3c4ccccc4)n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C18 compound treatment 1.05432893E8 7260000.0 0.63 1.00364084E8 6420000.0 0.56 0.8406 0.9985 3131585 CMLD2_000056 Cc1ccc(O[C@H]2C=C[C@@H](CC=C)O[C@@H]2COC(=O)NCc3cccc4ccccc34)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C19 compound treatment 8.6893415E7 -1.13E7 -0.97 7.925152E7 -1.47E7 -1.29 -1.5982 -0.9906 3131586 CMLD2_000057 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2ccc(cc2)C(=O)OC)C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C20 compound treatment 9.3205533E7 -4960000.0 -0.43 9.8262065E7 4310000.0 0.38 -0.0363 -0.0635 3010236 CMLD2_000058 C[C@H]1CC[C@@H]2N(CC(CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C21 compound treatment 1.06355943E8 8190000.0 0.71 9.2162969E7 -1790000.0 -0.16 0.3894 0.5378 3131587 CMLD2_000059 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2CC1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C22 compound treatment 1.05478409E8 7310000.0 0.63 1.02327722E8 8380000.0 0.73 0.9649 0.9972 3131703 CMLD2_000060 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C23 compound treatment 1.06249295E8 8080000.0 0.7 1.04372039E8 1.04E7 0.91 1.1385 0.9912 3010240 CMLD2_000061 OC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 C24 compound treatment 1.00901626E8 2730000.0 0.24 1.0480888E8 1.09E7 0.95 0.8389 0.8566 3131704 CMLD2_000062 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C4=O)c5ccccc5)C(=O)OC)c6ccccc6)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D01 compound treatment 1.00111491E8 1940000.0 0.17 1.04450181E8 1.05E7 0.92 0.7684 0.8225 3010292 CMLD2_000063 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D02 compound treatment 1.04272757E8 6100000.0 0.53 1.02060047E8 8110000.0 0.71 0.8747 0.9893 3131705 CMLD2_000064 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D03 compound treatment 1.05107569E8 6940000.0 0.6 1.0185587E8 7910000.0 0.69 0.913 0.9974 3131706 CMLD2_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D04 compound treatment 1.02344795E8 4170000.0 0.36 8.5397892E7 -8550000.0 -0.75 -0.2742 -0.3301 3010296 CMLD2_000066 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D05 compound treatment 9.4344172E7 -3830000.0 -0.33 9.6614607E7 2670000.0 0.23 -0.0687 -0.1698 3010274 CMLD2_000067 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D06 compound treatment 9.8881247E7 711000.0 0.06 9.4410584E7 462000.0 0.04 0.072 0.9794 3131707 CMLD2_000068 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D07 compound treatment 1.06329202E8 8160000.0 0.7 9.9686389E7 5740000.0 0.5 0.8534 0.9862 3131708 CMLD2_000069 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D08 compound treatment 9.6401239E7 -1770000.0 -0.15 8.2910211E7 -1.1E7 -0.97 -0.7911 -0.8089 3010278 CMLD2_000070 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D09 compound treatment 8.5718604E7 -1.25E7 -1.08 9.4774075E7 825000.0 0.07 -0.7094 -0.6581 3010279 CMLD2_000071 CN1CCN(CC(O)CN2CCCc3nc(C)c(C)cc23)CC1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D10 compound treatment 9.369916E7 -4470000.0 -0.39 9.0510671E7 -3440000.0 -0.3 -0.4858 -0.9924 3131709 CMLD2_000072 C[C@@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D11 mock treatment 1.0050819E8 2340000.0 0.2 9.70443E7 3100000.0 0.27 0.3344 0.9895 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D12 mock treatment 9.7089013E7 -1080000.0 -0.09 8.4154873E7 -9790000.0 -0.86 -0.6721 -0.7795 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D13 compound treatment 8.8745436E7 -9420000.0 -0.81 9.2131116E7 -1820000.0 -0.16 -0.6881 -0.8296 3010281 CMLD2_000073 Brc1ccc(cc1)C(=O)OC(CCc2ccccc2)C3=CCCCC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D14 compound treatment 9.4996245E7 -3170000.0 -0.27 9.0441393E7 -3510000.0 -0.31 -0.4109 -0.9984 3131710 CMLD2_000074 CCOC(=O)CC(C1CCCCC1=O)C(=O)OCC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D15 mock treatment 1.01108902E8 2940000.0 0.25 9.8009446E7 4060000.0 0.36 0.4308 0.9864 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D16 mock treatment 9.5885467E7 -2280000.0 -0.2 8.4033057E7 -9920000.0 -0.87 -0.7532 -0.8463 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D17 compound treatment 8.8442832E7 -9730000.0 -0.84 9.2217566E7 -1730000.0 -0.15 -0.7012 -0.8214 3131711 CMLD2_000075 COC(=O)C/C=C/[C@H](C)[C@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D18 compound treatment 7.6001175E7 -2.22E7 -1.91 6.3447943E7 -3.05E7 -2.67 -3.2415 -0.9867 3010283 CMLD2_000076 CCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D19 compound treatment 9.0822146E7 -7350000.0 -0.63 8.1231162E7 -1.27E7 -1.11 -1.2358 -0.9645 3131712 CMLD2_000077 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D20 compound treatment 1.01997711E8 3830000.0 0.33 8.9388695E7 -4560000.0 -0.4 -0.0484 -0.0934 3010285 CMLD2_000078 COC(=O)[C@@H]1CC[C@@H](C)[C@@H](N1)c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D21 compound treatment 9.5081511E7 -3090000.0 -0.27 1.02413934E8 8470000.0 0.74 0.3352 0.4257 3131713 CMLD2_000079 C[C@@H]1Cc2c(CO1)cnc3CCN(C)Cc32 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D22 compound treatment 9.8894254E7 724000.0 0.06 9.5930789E7 1980000.0 0.17 0.1669 0.905 3131714 CMLD2_000080 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D23 compound treatment 1.09224626E8 1.11E7 0.95 1.05492328E8 1.15E7 1.01 1.3895 0.9996 3010288 CMLD2_000081 COc1cc(cc(OC)c1OC)[C@@H]2N[C@@H](Cc3c2[nH]c4ccccc34)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 D24 compound treatment 1.08773754E8 1.06E7 0.92 9.7647624E7 3700000.0 0.32 0.8765 0.9023 3131715 CMLD2_000082 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E01 mock treatment 1.08879371E8 1.07E7 0.92 1.02307126E8 8360000.0 0.73 1.1713 0.9932 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E02 mock treatment 1.05070399E8 6900000.0 0.6 9.5779533E7 1830000.0 0.16 0.5347 0.8664 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E03 compound treatment 1.01779335E8 3610000.0 0.31 1.00475956E8 6530000.0 0.57 0.6244 0.9594 3010304 CMLD2_000083 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E04 compound treatment 1.00099239E8 1930000.0 0.17 9.4274504E7 326000.0 0.03 0.138 0.8163 3131716 CMLD2_000084 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E05 compound treatment 1.01909908E8 3740000.0 0.32 9.9646691E7 5700000.0 0.5 0.581 0.9779 3131717 CMLD2_000085 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E06 compound treatment 9.6887213E7 -1280000.0 -0.11 9.1464275E7 -2480000.0 -0.22 -0.2321 -0.9511 3010306 CMLD2_000086 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E07 compound treatment 9.832724E7 157000.0 0.01 9.4588445E7 640000.0 0.06 0.0492 0.8537 3131718 CMLD2_000087 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E08 compound treatment 8.9147414E7 -9020000.0 -0.78 8.6042006E7 -7910000.0 -0.69 -1.0404 -0.9982 3131719 CMLD2_000088 Brc1ccc(cc1)c2ccc3N(CCCc3n2)C(=O)NCCCN4=CC=NC4c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E09 mock treatment 9.5781471E7 -2390000.0 -0.21 9.2920911E7 -1030000.0 -0.09 -0.2095 -0.9308 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E10 mock treatment 9.1149256E7 -7020000.0 -0.61 8.8688381E7 -5260000.0 -0.46 -0.7543 -0.9908 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E11 compound treatment 9.6334293E7 -1840000.0 -0.16 9.4483669E7 535000.0 0.05 -0.079 -0.4779 3010320 CMLD2_000089 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)NCc3cccc4ccccc34)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E12 compound treatment 9.3938482E7 -4230000.0 -0.37 9.0698259E7 -3250000.0 -0.28 -0.4596 -0.9923 3131720 CMLD2_000090 CC(C)C(=O)N[C@H]1CCCN1C(=O)/C=C/c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E13 compound treatment 9.5603918E7 -2570000.0 -0.22 9.3978956E7 30300.0 0.0 -0.1549 -0.6986 3010323 CMLD2_000091 OC(COCc1ccccc1)C2=CCCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E14 compound treatment 8.9746465E7 -8420000.0 -0.73 9.1220383E7 -2730000.0 -0.24 -0.6833 -0.8923 3131721 CMLD2_000092 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3ccccc3O[C@]2([C@@H]1c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E15 compound treatment 9.4426266E7 -3740000.0 -0.32 9.2680627E7 -1270000.0 -0.11 -0.3071 -0.8983 3010326 CMLD2_000093 COc1cc(O)c(C(=O)/C=C/c2ccc3OCOc3c2)c(OC)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E16 mock treatment 9.3312263E7 -4860000.0 -0.42 9.3767623E7 -181000.0 -0.02 -0.3079 -0.7333 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E17 mock treatment 9.8630157E7 460000.0 0.04 9.8026456E7 4080000.0 0.36 0.2804 0.781 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E18 mock treatment 1.017175E8 3550000.0 0.31 9.8968388E7 5020000.0 0.44 0.5273 0.9845 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E19 compound treatment 9.7434864E7 -735000.0 -0.06 9.2946386E7 -1000000.0 -0.09 -0.1069 -0.9874 3131722 CMLD2_000094 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E20 compound treatment 9.9334765E7 1160000.0 0.1 9.7166427E7 3220000.0 0.28 0.2703 0.9038 3131840 CMLD2_000095 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)C(F)(F)F)c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E21 compound treatment 1.03323317E8 5150000.0 0.45 9.7369174E7 3420000.0 0.3 0.5264 0.9814 3010332 CMLD2_000096 C1Cc2nc(c3ccccc3)c(cc2CN1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E22 compound treatment 1.01324832E8 3150000.0 0.27 9.8003129E7 4050000.0 0.35 0.4436 0.9915 3131841 CMLD2_000097 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCOC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E23 compound treatment 1.05468578E8 7300000.0 0.63 1.02071142E8 8120000.0 0.71 0.9484 0.9982 3010340 CMLD2_000098 C[C@H]1CC[C@H](N[C@@H]1c2cccc(CC=C)c2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 E24 compound treatment 1.06733375E8 8560000.0 0.74 1.0219886E8 8250000.0 0.72 1.0336 0.9999 3131842 CMLD2_000099 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCCC4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F01 mock treatment 1.09038459E8 1.09E7 0.94 1.00202305E8 6250000.0 0.55 1.0508 0.967 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F02 mock treatment 1.04541228E8 6370000.0 0.55 9.480575E7 857000.0 0.08 0.4421 0.7961 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F03 compound treatment 1.03774684E8 5600000.0 0.48 9.9579062E7 5630000.0 0.49 0.6907 1.0 3131843 CMLD2_000100 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F04 compound treatment 9.8240663E7 70500.0 0.01 9.3301311E7 -647000.0 -0.06 -0.0358 -0.6275 3010347 CMLD2_000101 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F05 compound treatment 9.9621134E7 1450000.0 0.13 9.5976731E7 2030000.0 0.18 0.2141 0.9855 3131844 CMLD2_000102 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F06 compound treatment 9.4855455E7 -3310000.0 -0.29 9.204924E7 -1900000.0 -0.17 -0.32 -0.9666 3131845 CMLD2_000103 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F07 compound treatment 9.7056062E7 -1110000.0 -0.1 9.5774567E7 1830000.0 0.16 0.045 0.241 3011245 CMLD2_000104 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F08 compound treatment 9.1229345E7 -6940000.0 -0.6 8.8332651E7 -5620000.0 -0.49 -0.7714 -0.9951 3010203 CMLD2_000105 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F09 mock treatment 9.8665139E7 495000.0 0.04 9.397828E7 29600.0 0.0 0.0321 0.7486 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F10 mock treatment 9.2870285E7 -5300000.0 -0.46 8.930419E7 -4640000.0 -0.41 -0.6111 -0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F11 compound treatment 1.01301754E8 3130000.0 0.27 9.7053658E7 3100000.0 0.27 0.3834 1.0 3011246 CMLD2_000106 C[C@@]12CCC3C(CCc4cc(OCC5CO5)ccc34)C2CC[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F12 compound treatment 9.5018716E7 -3150000.0 -0.27 9.1955733E7 -1990000.0 -0.17 -0.3158 -0.9769 3011247 CMLD2_000107 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F13 compound treatment 9.9684558E7 1510000.0 0.13 9.5809269E7 1860000.0 0.16 0.2076 0.9941 3131846 CMLD2_000108 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(Br)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F14 compound treatment 9.2008324E7 -6160000.0 -0.53 8.9256357E7 -4690000.0 -0.41 -0.6667 -0.9918 3011248 CMLD2_000109 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F15 compound treatment 9.5245216E7 -2920000.0 -0.25 9.3709043E7 -240000.0 -0.02 -0.1935 -0.7632 1946418 CMLD2_000110 Fc1ccc(cc1)C(=O)/C=C/c2ccc3OCOc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F16 compound treatment 9.790123E7 -269000.0 -0.02 9.5498051E7 1550000.0 0.14 0.0795 0.5776 3011250 CMLD2_000111 OC(CCOC(c1ccccc1)(c2ccccc2)c3ccccc3)C4=CCCCC4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F17 mock treatment 1.03223742E8 5050000.0 0.44 9.9839661E7 5890000.0 0.52 0.6732 0.9966 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F18 mock treatment 1.00454038E8 2280000.0 0.2 1.00294008E8 6350000.0 0.56 0.5322 0.903 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F19 compound treatment 9.9229264E7 1060000.0 0.09 1.00581453E8 6630000.0 0.58 0.4751 0.8086 3131847 CMLD2_000112 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F20 compound treatment 9.891017E7 740000.0 0.06 9.6067669E7 2120000.0 0.19 0.1763 0.8989 3131848 CMLD2_000113 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1)c2ccc(Br)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F21 compound treatment 1.02925526E8 4760000.0 0.41 1.00429026E8 6480000.0 0.57 0.6915 0.9874 3011251 CMLD2_000114 CN1CCc2nc(CO)c(CO)cc2C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F22 compound treatment 1.01561443E8 3390000.0 0.29 9.7213648E7 3260000.0 0.29 0.4092 0.9999 3131849 CMLD2_000115 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F23 compound treatment 1.06249618E8 8080000.0 0.7 1.02753E8 8800000.0 0.77 1.0383 0.9988 3011252 CMLD2_000116 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(c3)N4CCOCC4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6cccc(c6)N7CCOCC7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 F24 compound treatment 1.05224068E8 7050000.0 0.61 1.02291437E8 8340000.0 0.73 0.9471 0.996 3131850 CMLD2_000117 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C)C4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G01 compound treatment 1.05576305E8 7410000.0 0.64 1.04306203E8 1.04E7 0.91 1.0933 0.9854 3131851 CMLD2_000118 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCN3CCOCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G02 compound treatment 1.07551006E8 9380000.0 0.81 9.9953597E7 6000000.0 0.53 0.9445 0.978 3131852 CMLD2_000119 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G03 mock treatment 1.06610112E8 8440000.0 0.73 1.00485794E8 6540000.0 0.57 0.92 0.9928 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G04 mock treatment 9.8990871E7 821000.0 0.07 9.407103E7 122000.0 0.01 0.0577 0.8048 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G05 compound treatment 9.7036316E7 -1130000.0 -0.1 9.6342624E7 2390000.0 0.21 0.0789 0.3412 3011253 CMLD2_000120 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G06 compound treatment 9.8553674E7 384000.0 0.03 9.3338559E7 -610000.0 -0.05 -0.0143 -0.2281 3131853 CMLD2_000121 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G07 compound treatment 1.00716561E8 2550000.0 0.22 9.5696438E7 1750000.0 0.15 0.2637 0.9842 3011254 CMLD2_000122 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)OC2CC(CCC3CC(=NO3)CC)OC4(CCCC(COC(=O)NCCC(C)C)O4)C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G08 compound treatment 9.6927787E7 -1240000.0 -0.11 9.2818751E7 -1130000.0 -0.1 -0.1458 -0.9992 3131854 CMLD2_000123 Cc1ccc(cc1)S(=O)(=O)NC(CCc2ccccc2)CC(=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G09 compound treatment 9.9421328E7 1250000.0 0.11 9.4122854E7 174000.0 0.02 0.0872 0.7989 3131855 CMLD2_000124 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)N3CCCCC3)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G10 compound treatment 9.282231E7 -5350000.0 -0.46 9.1831681E7 -2120000.0 -0.19 -0.4576 -0.9195 3011255 CMLD2_000125 O[C@H]1C=C(C=C)C2(OCCCO2)[C@H]3O[C@H]31 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G11 compound treatment 8.9596325E7 -8570000.0 -0.74 9.1917417E7 -2030000.0 -0.18 -0.6493 -0.8526 3011256 CMLD2_000126 OC(CCc1ccccc1)C2=CCCOC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G12 compound treatment 9.0470767E7 -7700000.0 -0.67 8.5306253E7 -8640000.0 -0.76 -1.0051 -0.9979 3131856 CMLD2_000127 C[C@H]1OC=C2[C@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](OC(=O)C)[C@H]7O[C@H]7C6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G13 compound treatment 9.612457E7 -2050000.0 -0.18 8.7833633E7 -6120000.0 -0.54 -0.5034 -0.8931 3011257 CMLD2_000128 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G14 compound treatment 8.9782577E7 -8390000.0 -0.72 8.514317E7 -8810000.0 -0.77 -1.0572 -0.9995 3131857 CMLD2_000129 CC/C=C\CCC(OC(=O)c1ccc(Br)cc1)C2=CCCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G15 compound treatment 9.5927751E7 -2240000.0 -0.19 9.4137579E7 189000.0 0.02 -0.1253 -0.6444 3011258 CMLD2_000130 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G16 mock treatment 9.1233368E7 -6940000.0 -0.6 8.6689962E7 -7260000.0 -0.64 -0.8729 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G17 compound treatment 9.8740469E7 570000.0 0.05 9.3908439E7 -40200.0 0.0 0.0323 0.6549 3131858 CMLD2_000131 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G18 compound treatment 6.662402E7 -3.15E7 -2.72 5.7814452E7 -3.61E7 -3.16 -4.1628 -0.9972 3131859 CMLD2_000132 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G19 mock treatment 1.02144492E8 3970000.0 0.34 9.1415515E7 -2530000.0 -0.22 0.086 0.2104 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G20 mock treatment 9.9759322E7 1590000.0 0.14 9.8630416E7 4680000.0 0.41 0.3868 0.8951 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G21 compound treatment 1.02068533E8 3900000.0 0.34 9.7801492E7 3850000.0 0.34 0.4765 1.0 3011259 CMLD2_000133 CN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G22 compound treatment 1.02463286E8 4290000.0 0.37 1.01017255E8 7070000.0 0.62 0.6996 0.97 3131977 CMLD2_000134 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G23 compound treatment 1.07989504E8 9820000.0 0.85 9.6838283E7 2890000.0 0.25 0.7785 0.8797 3011260 CMLD2_000135 C[C@H]1CC[C@@H]2N([C@@H]1c3cccc(CC=C)c3)C(=O)[C@@H]4CC[C@H](C)[C@H](N4C2=O)c5cccc(CC=C)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 G24 compound treatment 1.06454835E8 8280000.0 0.72 6.1430379E7 -3.25E7 -2.85 -1.5064 -0.5133 3131978 CMLD2_000136 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H01 compound treatment 1.07986314E8 9820000.0 0.85 1.05215417E8 1.13E7 0.99 1.2968 0.9972 3131979 CMLD2_000137 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H02 compound treatment 1.05890478E8 7720000.0 0.67 9.1475809E7 -2470000.0 -0.22 0.3185 0.4543 3131980 CMLD2_000138 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H03 mock treatment 1.06881673E8 8710000.0 0.75 1.04533015E8 1.06E7 0.93 1.1871 0.9947 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H04 mock treatment 9.1418288E7 -6750000.0 -0.58 8.8352407E7 -5600000.0 -0.49 -0.7587 -0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H05 compound treatment 1.00383226E8 2210000.0 0.19 9.9347564E7 5400000.0 0.47 0.4693 0.9207 3011261 CMLD2_000139 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H06 compound treatment 9.5055523E7 -3110000.0 -0.27 9.1470017E7 -2480000.0 -0.22 -0.3436 -0.9943 3131981 CMLD2_000140 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H07 compound treatment 9.7766729E7 -403000.0 -0.03 9.4548013E7 599000.0 0.05 0.0125 0.1977 3422360 CMLD2_000141 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H08 compound treatment 9.5572633E7 -2600000.0 -0.22 9.1113072E7 -2840000.0 -0.25 -0.3341 -0.9987 3010278 CMLD2_000142 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H09 compound treatment 1.00842552E8 2670000.0 0.23 9.6515086E7 2570000.0 0.22 0.322 0.9999 3011262 CMLD2_000143 CON(C)C(=O)c1nnc2c3ccccc3[nH]c2n1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H10 compound treatment 8.3300748E7 -1.49E7 -1.28 8.3144047E7 -1.08E7 -0.95 -1.5768 -0.9887 3011263 CMLD2_000144 C/C=C/C1=C(CO)C(=O)[C@@H]2O[C@@H]2C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H11 compound treatment 8.8276473E7 -9890000.0 -0.85 9.5743474E7 1790000.0 0.16 -0.4932 -0.5676 3011264 CMLD2_000145 CCOC(=O)CC(CC(=O)C)C(=O)OCC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H12 compound treatment 9.3467157E7 -4700000.0 -0.41 8.6735128E7 -7210000.0 -0.63 -0.7336 -0.9773 3131982 CMLD2_000146 CCOC(=O)C1=NO[C@@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H13 compound treatment 9.7054527E7 -1120000.0 -0.1 9.0945516E7 -3000000.0 -0.26 -0.254 -0.9073 3011265 CMLD2_000147 OC(C1CCCCC1)C2=CCCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H14 compound treatment 9.2939604E7 -5230000.0 -0.45 8.9908104E7 -4040000.0 -0.35 -0.5695 -0.9927 3011266 CMLD2_000148 OC(C1=CCCCC1=O)c2ccc(cc2)[N+](=O)[O-] 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H15 compound treatment 9.1244679E7 -6930000.0 -0.6 9.417126E7 223000.0 0.02 -0.4092 -0.6837 3131983 CMLD2_000149 CC1(C)O[C@H]2OC([C@H](O)CON3C(=O)c4ccccc4C3=O)[C@H](O)[C@H]2O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H16 compound treatment 8.4511864E7 -1.37E7 -1.18 7.7431761E7 -1.65E7 -1.45 -1.8563 -0.9949 3011267 CMLD2_000150 COCOc1ccc(Br)cc1C(=O)[C@@H]2O[C@H]2c3cccc(OC)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H17 compound treatment 9.8365971E7 196000.0 0.02 9.5426594E7 1480000.0 0.13 0.1034 0.7928 3131984 CMLD2_000151 C[C@@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@]42[C@H]5O[C@H](C)[C@@H]([C@@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H18 compound treatment 7.5388543E7 -2.28E7 -1.97 7.1664845E7 -2.23E7 -1.95 -2.7704 -1.0 3011268 CMLD2_000152 COc1ccc(C#C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H19 mock treatment 1.01199892E8 3030000.0 0.26 9.9340134E7 5390000.0 0.47 0.5187 0.9613 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H20 mock treatment 9.9301607E7 1130000.0 0.1 9.7239E7 3290000.0 0.29 0.2727 0.8968 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H21 compound treatment 1.0501214E8 6840000.0 0.59 1.02064076E8 8120000.0 0.71 0.9201 0.9958 3131985 CMLD2_000153 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H22 compound treatment 1.00466308E8 2300000.0 0.2 9.9093287E7 5140000.0 0.45 0.4586 0.9321 3131715 CMLD2_000154 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H23 compound treatment 1.08061883E8 9890000.0 0.85 1.02613738E8 8670000.0 0.76 1.1404 0.9982 3011247 CMLD2_000155 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 H24 compound treatment 1.06262729E8 8090000.0 0.7 8.0072091E7 -1.39E7 -1.21 -0.3645 -0.2601 3131986 CMLD2_000156 COC(=O)C1=C(C)N(Cc2ccccc2)c3c(C(=O)OC)c(C(=O)OC)c(C(=O)OC)c(=O)n3[C@@H]1c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I01 compound treatment 1.10006585E8 1.18E7 1.02 1.05371999E8 1.14E7 1.0 1.4298 0.9999 3131987 CMLD2_000157 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I02 compound treatment 1.00657311E8 2490000.0 0.21 9.7037243E7 3090000.0 0.27 0.343 0.9935 3011269 CMLD2_000158 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3cccc4ccccc34)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I03 compound treatment 1.03055676E8 4890000.0 0.42 9.8179106E7 4230000.0 0.37 0.5602 0.9979 3131988 CMLD2_000159 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I04 compound treatment 9.7471328E7 -699000.0 -0.06 9.72001E7 3250000.0 0.28 0.1585 0.545 3011270 CMLD2_000160 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I05 mock treatment 1.00937594E8 2770000.0 0.24 9.5961421E7 2010000.0 0.18 0.2936 0.9887 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I06 mock treatment 9.7407815E7 -762000.0 -0.07 9.2404926E7 -1540000.0 -0.14 -0.1421 -0.9454 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I07 compound treatment 9.6433344E7 -1740000.0 -0.15 9.4766207E7 818000.0 0.07 -0.0555 -0.3338 3422373 CMLD2_000161 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I08 compound treatment 9.4430824E7 -3740000.0 -0.32 9.2870532E7 -1080000.0 -0.09 -0.2951 -0.877 3011271 CMLD2_000162 COC(=O)NC/C=C\c1nc(CCCO)co1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I09 compound treatment 9.9637291E7 1470000.0 0.13 9.332281E7 -626000.0 -0.05 0.0509 0.3685 3131989 CMLD2_000163 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I10 compound treatment 8.9465655E7 -8700000.0 -0.75 8.980003E7 -4150000.0 -0.36 -0.7884 -0.9442 3011272 CMLD2_000164 CO[C@@H]1[C@@H](C)/C(=C\CC(=O)OC)/c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I11 compound treatment 9.4312988E7 -3860000.0 -0.33 9.3160068E7 -789000.0 -0.07 -0.2844 -0.8358 3131990 CMLD2_000165 CC(=NOCc1ccc(cc1)c2cc(no2)c3ccccc3)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I12 compound treatment 9.3110551E7 -5060000.0 -0.44 9.0167529E7 -3780000.0 -0.33 -0.543 -0.9906 3131991 CMLD2_000166 COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I13 compound treatment 9.7818655E7 -352000.0 -0.03 9.3320018E7 -629000.0 -0.06 -0.0604 -0.9607 3011273 CMLD2_000167 C=CC(=O)N1C(=O)c2ccccc2S1(=O)=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I14 compound treatment 9.4862585E7 -3310000.0 -0.29 8.9507169E7 -4440000.0 -0.39 -0.4769 -0.9885 3131992 CMLD2_000168 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#Cc3ccccc3)cc2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I15 compound treatment 9.4352149E7 -3820000.0 -0.33 9.1413031E7 -2540000.0 -0.22 -0.3901 -0.9814 3011274 CMLD2_000169 CC(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I16 mock treatment 9.2686281E7 -5480000.0 -0.47 9.0644992E7 -3300000.0 -0.29 -0.5394 -0.972 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I17 compound treatment 6.1375126E7 -3.68E7 -3.18 5.1876846E7 -4.21E7 -3.68 -4.8508 -0.9973 3131993 CMLD2_000170 C[C@H]1OC=C2[C@H](O)C3O[C@@H]3/C(=N\OCc4ccccc4)/[C@@]52[C@H]6OC(C)[C@@H](C15)C7=C6[C@H](O)[C@H]8O[C@H]8C7=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I18 compound treatment 9.0905405E7 -7260000.0 -0.63 8.7536043E7 -6410000.0 -0.56 -0.8405 -0.9985 3011312 CMLD2_000171 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I19 compound treatment 9.912866E7 958000.0 0.08 9.6727782E7 2780000.0 0.24 0.2305 0.8972 3131989 CMLD2_000172 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I20 compound treatment 9.8787444E7 617000.0 0.05 9.5564502E7 1620000.0 0.14 0.1377 0.9111 3011257 CMLD2_000173 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I21 mock treatment 1.03179286E8 5010000.0 0.43 9.6896217E7 2950000.0 0.26 0.4883 0.9695 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I22 mock treatment 1.00739712E8 2570000.0 0.22 9.7441436E7 3490000.0 0.31 0.3731 0.9876 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I23 compound treatment 9.0418375E7 -7750000.0 -0.67 9.7247871E7 3300000.0 0.29 -0.2693 -0.3693 3132111 CMLD2_000174 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(NC(=O)C)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(NC(=O)C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 I24 compound treatment 8.7909702E7 -1.03E7 -0.89 1.01409655E8 7460000.0 0.65 -0.1649 -0.1498 3131703 CMLD2_000175 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J01 compound treatment 1.09651775E8 1.15E7 0.99 9.9878465E7 5930000.0 0.52 1.0682 0.9544 3132112 CMLD2_000176 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J02 compound treatment 1.03475615E8 5310000.0 0.46 9.6873149E7 2920000.0 0.26 0.505 0.9621 3011347 CMLD2_000177 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J03 compound treatment 1.0572254E8 7550000.0 0.65 1.0239502E8 8450000.0 0.74 0.984 0.9981 3132113 CMLD2_000178 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J04 compound treatment 9.5583121E7 -2590000.0 -0.22 9.6179403E7 2230000.0 0.2 -0.02 -0.0673 3132114 CMLD2_000179 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J05 mock treatment 1.00369492E8 2200000.0 0.19 9.9094708E7 5150000.0 0.45 0.4528 0.9263 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J06 mock treatment 9.2244041E7 -5930000.0 -0.51 9.2353194E7 -1600000.0 -0.14 -0.4607 -0.8683 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J07 compound treatment 9.8948506E7 778000.0 0.07 9.7768626E7 3820000.0 0.33 0.2839 0.8326 3011348 CMLD2_000180 CC(C)C[C@H](NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45)C(=O)NCC(c6ccccc6)c7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J08 compound treatment 7.8621057E7 -1.95E7 -1.69 8.0309335E7 -1.36E7 -1.19 -2.038 -0.9856 3132115 CMLD2_000181 CO[C@H]1C[C@@H]2C[C@H](CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2)OC(=O)\C=C/CCc4coc(\C=C/CNC(=O)OC)n4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J09 compound treatment 9.6016283E7 -2150000.0 -0.19 9.6125756E7 2180000.0 0.19 0.0032 0.0119 3011349 CMLD2_000182 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J10 compound treatment 9.2219793E7 -5950000.0 -0.51 8.7440389E7 -6510000.0 -0.57 -0.7662 -0.9987 3132116 CMLD2_000183 CO[C@@H](C(C)C)[C@@H](C)C1OC(=O)CC1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J11 compound treatment 9.6497455E7 -1670000.0 -0.14 9.515931E7 1210000.0 0.11 -0.0272 -0.152 3132117 CMLD2_000184 COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@](Oc3ccccc3C1=O)(C(=O)OC)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J12 compound treatment 8.8336912E7 -9830000.0 -0.85 8.973019E7 -4220000.0 -0.37 -0.8616 -0.9304 3011350 CMLD2_000185 CC(=NOCc1cccc(c1)c2cc(no2)c3ccccc3)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J13 compound treatment 9.7841312E7 -329000.0 -0.03 9.3477831E7 -471000.0 -0.04 -0.0492 -0.9835 3132118 CMLD2_000186 CC(C)C(=O)N[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J14 compound treatment 9.3298217E7 -4870000.0 -0.42 8.9052192E7 -4900000.0 -0.43 -0.6006 -1.0 3011352 CMLD2_000187 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C=C)cc2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J15 compound treatment 9.4696109E7 -3470000.0 -0.3 9.5060885E7 1110000.0 0.1 -0.1433 -0.4544 3132119 CMLD2_000188 CO[C@H](CO)COc1ccc(OC)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J16 compound treatment 9.3404787E7 -4770000.0 -0.41 9.02657E7 -3680000.0 -0.32 -0.519 -0.9927 3011353 CMLD2_000189 Oc1ccccc1C(=O)/C=C/c2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J17 compound treatment 9.7756074E7 -414000.0 -0.04 9.5049892E7 1100000.0 0.1 0.0429 0.4169 3132120 CMLD2_000190 CC(=NOCc1ccc(cc1)c2cn(nn2)[C@@H]3COC[C@H]3O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J18 compound treatment 9.376942E7 -4400000.0 -0.38 8.6078783E7 -7870000.0 -0.69 -0.7558 -0.9607 3011354 CMLD2_000191 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J19 compound treatment 1.03730286E8 5560000.0 0.48 1.01767944E8 7820000.0 0.68 0.8235 0.985 3132121 CMLD2_000192 C[C@@H]1CC[C@@H]2N(CC(COCC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J20 compound treatment 9.7587783E7 -582000.0 -0.05 9.3099685E7 -849000.0 -0.07 -0.0881 -0.982 3011355 CMLD2_000193 CC(C)CCN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J21 mock treatment 1.02784228E8 4610000.0 0.4 9.9989135E7 6040000.0 0.53 0.6556 0.9903 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J22 mock treatment 9.7803669E7 -366000.0 -0.03 9.5928187E7 1980000.0 0.17 0.1001 0.5685 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J23 compound treatment 9.539405E7 -2780000.0 -0.24 1.01990684E8 8040000.0 0.7 0.3281 0.4413 3132122 CMLD2_000194 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(Br)c3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5cccc(c5)N6CCOCC6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 J24 compound treatment 1.07538056E8 9370000.0 0.81 9.8121579E7 4170000.0 0.37 0.8304 0.9354 3132123 CMLD2_000195 CCC(=O)[C@@]1(O[C@@]23[C@H]4[C@@H]1CCOC4=O)C(=O)N3[C@@H](C(=C(C)N2Cc5ccccc5)C(=O)OC)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K01 compound treatment 1.06046726E8 7880000.0 0.68 1.03360499E8 9410000.0 0.82 1.0635 0.9955 3132124 CMLD2_000196 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K02 compound treatment 1.00757932E8 2590000.0 0.22 9.925072E7 5300000.0 0.46 0.4862 0.9439 3011357 CMLD2_000197 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K03 compound treatment 1.05790582E8 7620000.0 0.66 1.02301064E8 8350000.0 0.73 0.9823 0.9986 3132125 CMLD2_000198 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K04 compound treatment 9.4820754E7 -3350000.0 -0.29 8.3134451E7 -1.08E7 -0.95 -0.8738 -0.8829 3132126 CMLD2_000199 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCCc6ccc(F)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K05 compound treatment 1.05241107E8 7070000.0 0.61 1.03872721E8 9920000.0 0.87 1.046 0.9852 3011359 CMLD2_000200 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K06 compound treatment 9.7473291E7 -697000.0 -0.06 8.9980292E7 -3970000.0 -0.35 -0.2881 -0.8175 3132127 CMLD2_000201 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K07 mock treatment 9.9755926E7 1590000.0 0.14 9.3215299E7 -733000.0 -0.06 0.0515 0.3403 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K08 mock treatment 9.1753801E7 -6420000.0 -0.55 9.5463805E7 1520000.0 0.13 -0.2981 -0.5232 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K09 compound treatment 9.5166567E7 -3000000.0 -0.26 9.1944081E7 -2000000.0 -0.18 -0.3075 -0.9819 3011360 CMLD2_000202 COc1cccc(c1)[C@H](O)Cn2cc(nn2)c3ccc(CON=C(C)C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K10 compound treatment 8.7448149E7 -1.07E7 -0.93 8.5891538E7 -8060000.0 -0.71 -1.1535 -0.991 3132128 CMLD2_000203 Cc1ccc2[nH]c3nc(CCCn4ccnc4c5ccccc5)nnc3c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K11 compound treatment 9.3092558E7 -5080000.0 -0.44 9.1527564E7 -2420000.0 -0.21 -0.4599 -0.9443 3011361 CMLD2_000204 COC(=O)C1=C(C)[C@@H](O)[C@@H](C)[C@@H](O1)c2c(OC)c(OC)c(C)c(OC)c2OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K12 compound treatment 5.7064683E7 -4.11E7 -3.55 5.5700786E7 -3.82E7 -3.35 -4.8774 -0.9996 3132129 CMLD2_000205 C[C@H]1OC=C2[C@H](OC(=O)C)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](O)[C@H]7O[C@H]7C6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K13 compound treatment 9.8982259E7 812000.0 0.07 9.16242E7 -2320000.0 -0.2 -0.0942 -0.438 3011362 CMLD2_000206 CO[C@H]1C[C@@H]2C[C@H](O)CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K14 compound treatment 9.2741133E7 -5430000.0 -0.47 9.1265896E7 -2680000.0 -0.23 -0.4976 -0.9489 3011258 CMLD2_000207 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K15 mock treatment 8.5518716E7 -1.27E7 -1.09 8.0684817E7 -1.33E7 -1.16 -1.5935 -0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K16 mock treatment 9.4893783E7 -3280000.0 -0.28 7.9190383E7 -1.48E7 -1.29 -1.1134 -0.8421 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K17 compound treatment 2.6593925E7 -7.16E7 -6.18 2.2641961E7 -7.13E7 -6.24 -8.7842 -1.0 3132248 CMLD2_000208 CCN1C(=O)[C@H]2CC=C3[C@H]([C@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C53OCCCO5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K18 compound treatment 9.9629939E7 1460000.0 0.13 9.6090827E7 2140000.0 0.19 0.2217 0.9814 3011363 CMLD2_000209 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K19 compound treatment 1.01796517E8 3630000.0 0.31 1.00928235E8 6980000.0 0.61 0.6534 0.9518 3132249 CMLD2_000210 C[C@@H]1CC[C@@H]2N(CC(COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K20 compound treatment 1.01205271E8 3040000.0 0.26 9.7920571E7 3970000.0 0.35 0.4312 0.9903 3011399 CMLD2_000211 CCCCc1nc2CCN(CCC(C)C)Cc2c3CO[C@@H](C)Cc13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K21 compound treatment 1.0326972E8 5100000.0 0.44 9.6402829E7 2450000.0 0.21 0.4633 0.9455 3132250 CMLD2_000212 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K22 compound treatment 1.02000343E8 3830000.0 0.33 9.9917534E7 5970000.0 0.52 0.6033 0.9757 3011400 CMLD2_000213 C[C@@H]1CC[C@H](N[C@H]1c2ccc(cc2)c3ccco3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K23 mock treatment 1.05421632E8 7250000.0 0.63 1.01981849E8 8030000.0 0.7 0.94 0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 K24 mock treatment 1.05307793E8 7140000.0 0.62 9.5996519E7 2050000.0 0.18 0.5627 0.8764 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L01 compound treatment 1.0884807E8 1.07E7 0.92 9.265558E7 -1290000.0 -0.11 0.5721 0.6157 3132251 CMLD2_000214 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L02 compound treatment 1.00670534E8 2500000.0 0.22 9.9206137E7 5260000.0 0.46 0.4781 0.9405 3132252 CMLD2_000215 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L03 compound treatment 1.06743191E8 8570000.0 0.74 1.0216917E8 8220000.0 0.72 1.0323 0.9999 3011402 CMLD2_000216 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L04 compound treatment 1.03379744E8 5210000.0 0.45 9.2533735E7 -1410000.0 -0.12 0.2306 0.4941 3132253 CMLD2_000217 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L05 compound treatment 9.3871086E7 -4300000.0 -0.37 1.01057374E8 7110000.0 0.62 0.1774 0.2448 3132254 CMLD2_000218 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L06 compound treatment 9.8645911E7 476000.0 0.04 9.8511616E7 4560000.0 0.4 0.3114 0.7758 3011403 CMLD2_000219 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L07 mock treatment 1.00395465E8 2230000.0 0.19 1.0116504E8 7220000.0 0.63 0.5825 0.8823 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L08 mock treatment 9.4081134E7 -4090000.0 -0.35 9.0206258E7 -3740000.0 -0.33 -0.4813 -0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L09 compound treatment 9.8380796E7 211000.0 0.02 9.5885058E7 1940000.0 0.17 0.1327 0.7785 3132255 CMLD2_000220 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L10 compound treatment 9.1224385E7 -6950000.0 -0.6 9.1775986E7 -2170000.0 -0.19 -0.5587 -0.8877 3132256 CMLD2_000221 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(C)c(C)cc45)CCCc3n2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L11 compound treatment 9.2366909E7 -5800000.0 -0.5 9.6006333E7 2060000.0 0.18 -0.2271 -0.4264 3011404 CMLD2_000222 CCOC(=O)C1=NO[C@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L12 compound treatment 9.4028838E7 -4140000.0 -0.36 8.7097051E7 -6850000.0 -0.6 -0.6769 -0.9695 3011405 CMLD2_000223 OC(CCc1ccccc1)C2=CCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L13 compound treatment 9.4997206E7 -3170000.0 -0.27 9.0671173E7 -3280000.0 -0.29 -0.3966 -0.9997 3132257 CMLD2_000224 OC(CCc1ccccc1)C23OC3CCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L14 compound treatment 8.6843812E7 -1.13E7 -0.98 8.8018805E7 -5930000.0 -0.52 -1.0587 -0.956 3132258 CMLD2_000225 CCCNC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L15 mock treatment 9.7635111E7 -535000.0 -0.05 7.3664006E7 -2.03E7 -1.78 -1.288 -0.7253 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L16 mock treatment 9.3913233E7 -4260000.0 -0.37 7.829816E7 -1.57E7 -1.37 -1.2285 -0.8663 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L17 compound treatment 9.8261791E7 91600.0 0.01 8.8659095E7 -5290000.0 -0.46 -0.3217 -0.6949 3011407 CMLD2_000226 C[C@H]1CC[C@@H]2N([C@@H]1c3ccccc3)C(=O)[C@@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L18 compound treatment 5.832635E7 -3.98E7 -3.44 4.6497888E7 -4.75E7 -4.15 -5.3699 -0.9956 3132259 CMLD2_000227 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L19 compound treatment 1.03811922E8 5640000.0 0.49 9.9179932E7 5230000.0 0.46 0.6683 0.9995 3132260 CMLD2_000228 C[C@@H]1CC[C@@H]2N(CC(CN3C(=O)c4ccccc4C3=O)OC2=O)[C@H]1c5ccc(Br)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L20 compound treatment 1.01739561E8 3570000.0 0.31 9.5132021E7 1180000.0 0.1 0.2912 0.8955 3011408 CMLD2_000229 CC(C)CCN1CCc2nc(COc3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L21 compound treatment 9.9434685E7 1260000.0 0.11 1.00428273E8 6480000.0 0.57 0.4782 0.8281 3132261 CMLD2_000230 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L22 compound treatment 1.02049223E8 3880000.0 0.34 9.9558544E7 5610000.0 0.49 0.5841 0.9826 3011409 CMLD2_000231 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#CCN(C)C)cc2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L23 mock treatment 1.06505861E8 8340000.0 0.72 1.03236969E8 9290000.0 0.81 1.0839 0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 L24 mock treatment 1.07534734E8 9360000.0 0.81 1.0206913E8 8120000.0 0.71 1.0745 0.9979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M01 compound treatment 1.0550007E8 7330000.0 0.63 1.07476634E8 1.35E7 1.18 1.2848 0.957 3132262 CMLD2_000232 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc4ccccc34)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M02 compound treatment 1.06324447E8 8150000.0 0.7 9.6201191E7 2250000.0 0.2 0.6374 0.8715 3132263 CMLD2_000233 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M03 compound treatment 1.07859698E8 9690000.0 0.84 1.06990222E8 1.3E7 1.14 1.3989 0.9884 3011410 CMLD2_000234 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M04 compound treatment 9.8614657E7 444000.0 0.04 9.5600663E7 1650000.0 0.14 0.1294 0.8649 3132264 CMLD2_000235 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M05 compound treatment 1.03063084E8 4890000.0 0.42 9.6805322E7 2860000.0 0.25 0.4756 0.9686 3132265 CMLD2_000236 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M06 compound treatment 1.01447867E8 3280000.0 0.28 9.3516799E7 -432000.0 -0.04 0.1735 0.6073 3011411 CMLD2_000237 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M07 compound treatment 9.6338182E7 -1830000.0 -0.16 9.8861788E7 4910000.0 0.43 0.1922 0.4194 3132266 CMLD2_000238 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccncc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M08 compound treatment 9.6015927E7 -2150000.0 -0.19 8.3004567E7 -1.09E7 -0.96 -0.8088 -0.829 3011412 CMLD2_000239 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M09 mock treatment 1.01034952E8 2860000.0 0.25 9.6333829E7 2390000.0 0.21 0.3226 0.9964 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M10 mock treatment 9.4104886E7 -4070000.0 -0.35 9.2130715E7 -1820000.0 -0.16 -0.3608 -0.9359 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M11 compound treatment 7.1434041E7 -2.67E7 -2.31 6.795892E7 -2.6E7 -2.27 -3.2413 -1.0 3132389 CMLD2_000240 COC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M12 compound treatment 9.1820685E7 -6350000.0 -0.55 7.0563658E7 -2.34E7 -2.05 -1.835 -0.866 3011413 CMLD2_000241 O=C1CCCC(C1)C2=CCCCC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M13 mock treatment 9.6679126E7 -1490000.0 -0.13 8.8780932E7 -5170000.0 -0.45 -0.4109 -0.8737 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M14 mock treatment 8.1616748E7 -1.66E7 -1.43 8.3279086E7 -1.07E7 -0.93 -1.6713 -0.9787 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M15 compound treatment 7.9953108E7 -1.82E7 -1.57 8.7595747E7 -6350000.0 -0.56 -1.5057 -0.9023 3132390 CMLD2_000242 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCCc2nc1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M16 compound treatment 8.3562599E7 -1.46E7 -1.26 8.5314158E7 -8630000.0 -0.76 -1.4265 -0.97 3011415 CMLD2_000243 CCO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M17 mock treatment 8.992709E7 -8240000.0 -0.71 9.60166E7 2070000.0 0.18 -0.3755 -0.5111 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M18 compound treatment 7.8725263E7 -1.94E7 -1.68 7.2346833E7 -2.16E7 -1.89 -2.5244 -0.9983 3132391 CMLD2_000244 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCC2CCCCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M19 compound treatment 9.9880585E7 1710000.0 0.15 9.9005414E7 5060000.0 0.44 0.4174 0.8946 3132392 CMLD2_000245 C[C@@H]1CC[C@@H]2N(CC(Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M20 compound treatment 9.6814391E7 -1360000.0 -0.12 9.2943013E7 -1010000.0 -0.09 -0.145 -0.9901 3011466 CMLD2_000246 COc1ccc(cc1)c2nc3CCN(CCC(C)C)Cc3c4CO[C@@H](C)Cc24 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M21 compound treatment 8.917022E7 -9000000.0 -0.78 8.1812204E7 -1.21E7 -1.06 -1.3007 -0.9882 3132393 CMLD2_000247 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCOC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M22 compound treatment 1.03456064E8 5290000.0 0.46 8.7615899E7 -6330000.0 -0.55 -0.0691 -0.0962 3011467 CMLD2_000248 C[C@H]1CC[C@H](N[C@@H]1c2cccc(c2)N3CCCC3=O)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M23 compound treatment 1.0601557E8 7850000.0 0.68 1.00163355E8 6210000.0 0.54 0.8637 0.9941 3132394 CMLD2_000249 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 M24 compound treatment 9.4338688E7 -3830000.0 -0.33 9.9529458E7 5580000.0 0.49 0.1114 0.1888 3132261 CMLD2_000250 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N01 compound treatment 1.03764928E8 5590000.0 0.48 1.07078982E8 1.31E7 1.15 1.1543 0.9259 3132395 CMLD2_000251 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N02 compound treatment 1.03009577E8 4840000.0 0.42 1.04930001E8 1.1E7 0.96 0.9751 0.9305 3132396 CMLD2_000252 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N03 compound treatment 1.06804645E8 8630000.0 0.75 9.5044636E7 1100000.0 0.1 0.5952 0.7915 3011471 CMLD2_000253 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N04 compound treatment 8.9063341E7 -9110000.0 -0.79 9.9790526E7 5840000.0 0.51 -0.1947 -0.2075 3132397 CMLD2_000254 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N05 compound treatment 9.5756509E7 -2410000.0 -0.21 1.01972796E8 8020000.0 0.7 0.3492 0.4766 3011472 CMLD2_000255 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N06 compound treatment 9.9461784E7 1290000.0 0.11 9.9376371E7 5430000.0 0.48 0.4148 0.85 3132398 CMLD2_000256 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N07 compound treatment 1.00466657E8 2300000.0 0.2 9.0357921E7 -3590000.0 -0.31 -0.082 -0.2205 3132399 CMLD2_000257 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccc5OCOc5c4)O3)O2)OC(=O)NCc6cccc7ccccc67 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N08 compound treatment 8.8014912E7 -1.02E7 -0.88 9.5760281E7 1810000.0 0.16 -0.5081 -0.5701 3011473 CMLD2_000258 Cc1ccc(cc1)S(=O)(=O)n2c3ccccc3c4nnc(nc24)C(=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N09 mock treatment 1.00253557E8 2080000.0 0.18 9.7288228E7 3340000.0 0.29 0.3339 0.9729 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N10 mock treatment 8.7346535E7 -1.08E7 -0.93 8.4819834E7 -9130000.0 -0.8 -1.226 -0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N11 compound treatment 7.4287346E7 -2.39E7 -2.06 7.0071083E7 -2.39E7 -2.09 -2.9363 -1.0 3011475 CMLD2_000259 BrC1=CC(=C)[C@@H]2O[C@@H]2C31OCCCO3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N12 compound treatment 8.2694927E7 -1.55E7 -1.34 7.6996674E7 -1.7E7 -1.48 -1.9942 -0.9986 3132400 CMLD2_000260 CCCCOC(OCCCC)C(O)CSc1ccc2ccccc2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N13 mock treatment 9.7875714E7 -294000.0 -0.03 8.2813486E7 -1.11E7 -0.97 -0.7071 -0.7253 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N14 mock treatment 8.8940625E7 -9230000.0 -0.8 8.6923163E7 -7030000.0 -0.61 -0.9985 -0.9918 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N15 compound treatment 7.128845E7 -2.69E7 -2.32 8.8276496E7 -5670000.0 -0.5 -1.9928 -0.8393 3011477 CMLD2_000261 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N16 compound treatment 8.1709158E7 -1.65E7 -1.42 7.9329611E7 -1.46E7 -1.28 -1.91 -0.9986 3132401 CMLD2_000262 CO[C@@H](C(C)C)[C@@H](C)C1OC1CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N17 compound treatment 6.8119879E7 -3.01E7 -2.6 6.4676894E7 -2.93E7 -2.56 -3.6468 -1.0 4845 CMLD2_000263 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(O[C@]2([C@@H]1c4ccccc4)c5ccc(OC)cc5)cc(OC)cc3OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N18 compound treatment 8.5679842E7 -1.25E7 -1.08 8.9657294E7 -4290000.0 -0.38 -1.0284 -0.9003 3011479 CMLD2_000264 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2cc(OC)c(OC)c(OC)c2)C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N19 compound treatment 1.01829111E8 3660000.0 0.32 9.4911411E7 963000.0 0.08 0.283 0.8654 3132403 CMLD2_000265 C[C@H]1CC[C@@H]2N(CC(COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N20 compound treatment 9.9626761E7 1460000.0 0.13 9.3679003E7 -270000.0 -0.02 0.0723 0.5646 3011480 CMLD2_000266 C[C@H]1Cc2c(nc3CCN(CCOc4ccccc4)Cc3c2CO1)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N21 compound treatment 8.9347099E7 -8820000.0 -0.76 8.1027658E7 -1.29E7 -1.13 -1.3385 -0.9815 3132404 CMLD2_000267 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N22 compound treatment 9.3163414E7 -5010000.0 -0.43 9.7180364E7 3230000.0 0.28 -0.1058 -0.2047 3011481 CMLD2_000268 C[C@@H]1CC[C@H](N[C@H]1c2ccc(NC(=O)C)cc2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N23 compound treatment 1.03707601E8 5540000.0 0.48 9.9926109E7 5980000.0 0.52 0.7081 0.999 3132405 CMLD2_000269 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@H](C(C)C)N(C)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 N24 compound treatment 1.02681314E8 4510000.0 0.39 9.4372248E7 424000.0 0.04 0.3017 0.7709 3131577 CMLD2_000270 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O01 compound treatment 1.09679345E8 1.15E7 0.99 1.04397265E8 1.04E7 0.91 1.3495 0.9991 3132406 CMLD2_000271 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O02 compound treatment 1.01054746E8 2880000.0 0.25 9.6402226E7 2450000.0 0.21 0.328 0.9973 3132407 CMLD2_000272 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6ccc7OCOc7c6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O03 compound treatment 8.9247707E7 -8920000.0 -0.77 9.0938417E7 -3010000.0 -0.26 -0.7312 -0.8978 3011482 CMLD2_000273 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O04 compound treatment 1.03346358E8 5180000.0 0.45 9.4790146E7 841000.0 0.07 0.3682 0.8126 3132527 CMLD2_000274 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O05 compound treatment 1.05423889E8 7250000.0 0.63 1.01315418E8 7370000.0 0.64 0.8989 0.9999 3011483 CMLD2_000275 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O06 compound treatment 9.7894376E7 -276000.0 -0.02 9.4580873E7 632000.0 0.06 0.0223 0.3699 3132528 CMLD2_000276 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O07 compound treatment 9.838847E7 218000.0 0.02 9.204458E7 -1900000.0 -0.17 -0.1045 -0.6231 3011485 CMLD2_000277 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O08 compound treatment 9.7988706E7 -181000.0 -0.02 9.4894372E7 946000.0 0.08 0.0474 0.5632 3132529 CMLD2_000278 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O09 compound treatment 8.784022E7 -1.03E7 -0.89 7.5729209E7 -1.82E7 -1.59 -1.7584 -0.9624 3011486 CMLD2_000279 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H](O)[C@H]1C)c2c(OC)c(OC)c(C)c(OC)c2OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O10 compound treatment 3.2090691E7 -6.61E7 -5.71 2.8670704E7 -6.53E7 -5.71 -8.0754 -1.0 3132530 CMLD2_000280 OC(CCCCBr)C1=CCCCC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O11 mock treatment 9.5977982E7 -2190000.0 -0.19 8.8250797E7 -5700000.0 -0.5 -0.4865 -0.9121 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O12 mock treatment 9.1812136E7 -6360000.0 -0.55 8.8148033E7 -5800000.0 -0.51 -0.7473 -0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O13 compound treatment 7.3417535E7 -2.48E7 -2.14 8.3017387E7 -1.09E7 -0.96 -2.1882 -0.9343 3132531 CMLD2_000281 COC(=O)C/C=C/[C@H](C)[C@@H](OCc1ccccc1Br)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O14 compound treatment 2.1056916E7 -7.71E7 -6.66 2.2090349E7 -7.19E7 -6.29 -9.1565 -0.9996 3011535 CMLD2_000282 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O15 compound treatment 9.2294094E7 -5880000.0 -0.51 8.4264562E7 -9680000.0 -0.85 -0.9582 -0.9699 3132532 CMLD2_000283 Nc1ccccc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O16 compound treatment 9.4790969E7 -3380000.0 -0.29 8.8425253E7 -5520000.0 -0.48 -0.5482 -0.9708 3131858 CMLD2_000284 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O17 mock treatment 9.9659428E7 1490000.0 0.13 9.3743049E7 -206000.0 -0.02 0.0782 0.6023 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O18 compound treatment 9.6108615E7 -2060000.0 -0.18 9.0758237E7 -3190000.0 -0.28 -0.3233 -0.9764 3011536 CMLD2_000285 OC[C@H]1O[C@@H](C=C[C@@H]1O)C#Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O19 compound treatment 1.00499699E8 2330000.0 0.2 1.0212086E8 8170000.0 0.72 0.648 0.8722 3132533 CMLD2_000286 C[C@H]1CC[C@@H]2N(C[C@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O20 compound treatment 1.03293851E8 5120000.0 0.44 9.8558073E7 4610000.0 0.4 0.5982 0.9989 3011537 CMLD2_000287 C[C@H]1Cc2c(COc3ccccc3)nc4CCN(CCOc5ccccc5)Cc4c2CO1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O21 compound treatment 1.0313306E8 4960000.0 0.43 1.06291791E8 1.23E7 1.08 1.067 0.9181 3132534 CMLD2_000288 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O22 compound treatment 1.03652898E8 5480000.0 0.47 9.9847544E7 5900000.0 0.52 0.6999 0.9991 3011538 CMLD2_000289 C[C@@H]1CC[C@H](N[C@H]1c2cccc(c2)N3CCOCC3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O23 compound treatment 1.07617611E8 9450000.0 0.82 1.01752883E8 7800000.0 0.68 1.06 0.9961 3132535 CMLD2_000290 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)c3ccccc3)c4ccccc4)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 O24 compound treatment 1.05846316E8 7680000.0 0.66 1.02776254E8 8830000.0 0.77 1.0151 0.9971 3132250 CMLD2_000291 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P01 compound treatment 1.09023637E8 1.09E7 0.94 9.5689395E7 1740000.0 0.15 0.7706 0.8114 3132536 CMLD2_000292 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P02 compound treatment 9.7642587E7 -528000.0 -0.05 1.00390648E8 6440000.0 0.56 0.3664 0.6478 3132537 CMLD2_000293 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P03 compound treatment 9.0860711E7 -7310000.0 -0.63 8.5799181E7 -8150000.0 -0.71 -0.9507 -0.9982 3011540 CMLD2_000294 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P04 compound treatment 1.01208047E8 3040000.0 0.26 9.6996086E7 3050000.0 0.27 0.3741 1.0 3132538 CMLD2_000295 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P05 compound treatment 1.04161272E8 5990000.0 0.52 9.9528906E7 5580000.0 0.49 0.7112 0.9996 3011541 CMLD2_000296 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P06 compound treatment 1.01910964E8 3740000.0 0.32 9.7856089E7 3910000.0 0.34 0.4703 0.9996 3132539 CMLD2_000297 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P07 compound treatment 1.03334435E8 5160000.0 0.45 9.5691391E7 1740000.0 0.15 0.4233 0.8979 3011542 CMLD2_000298 CCN(CC)CC(O)CN1CCCCc2nc(C)c(C)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P08 compound treatment 9.6322889E7 -1850000.0 -0.16 9.2853721E7 -1090000.0 -0.1 -0.1806 -0.9702 3131847 CMLD2_000299 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P09 compound treatment 7.6833857E7 -2.13E7 -1.84 8.4046705E7 -9900000.0 -0.87 -1.9159 -0.9408 3132540 CMLD2_000300 C[C@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5O[C@H](C)[C@@H]([C@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P10 compound treatment 6.1270926E7 -3.69E7 -3.19 6.8024888E7 -2.59E7 -2.27 -3.8579 -0.9861 3011543 CMLD2_000301 COCOc1ccc(Br)cc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P11 mock treatment 9.9162337E7 992000.0 0.09 9.2106728E7 -1840000.0 -0.16 -0.0534 -0.2924 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P12 mock treatment 9.1901325E7 -6270000.0 -0.54 8.665017E7 -7300000.0 -0.64 -0.8345 -0.9966 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P13 compound treatment 7.8869818E7 -1.93E7 -1.67 6.7689401E7 -2.63E7 -2.3 -2.8038 -0.9876 3132541 CMLD2_000302 COC(OC)[C@@H](C)[C@H](OC)[C@@H](C)[C@H](OC)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P14 compound treatment 8.308965E7 -1.51E7 -1.3 8.5233117E7 -8720000.0 -0.76 -1.4604 -0.9675 3011544 CMLD2_000303 CC(C)c1ccc(C)n1C(=O)OC(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P15 compound treatment 1.00500639E8 2330000.0 0.2 8.974072E7 -4210000.0 -0.37 -0.1181 -0.2813 3011545 CMLD2_000304 Brc1ccc(cc1)[C@@H]2OC(=O)C[C@@H]2c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P16 compound treatment 9.7027211E7 -1140000.0 -0.1 8.8338185E7 -5610000.0 -0.49 -0.417 -0.8326 3132542 CMLD2_000305 COC(=O)[C@H]1[C@@H](C(=O)[C@]2(O)c3ccccc3O[C@@]12c4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P17 mock treatment 1.01502347E8 3330000.0 0.29 9.4512465E7 564000.0 0.05 0.2384 0.8164 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P18 compound treatment 9.7588907E7 -581000.0 -0.05 9.4003183E7 54500.0 0.0 -0.0321 -0.637 3132543 CMLD2_000306 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P19 compound treatment 1.05199914E8 7030000.0 0.61 9.8747228E7 4800000.0 0.42 0.7263 0.9838 3011546 CMLD2_000307 C[C@@H]1CCC2N(C[C@H](O)CN(Cc3ccccc3)C2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P20 compound treatment 1.01642383E8 3470000.0 0.3 9.7343066E7 3390000.0 0.3 0.4221 1.0 3132544 CMLD2_000308 CCCCc1nc2CCN(CCOc3ccccc3)Cc2c4CO[C@@H](C)Cc14 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P21 compound treatment 1.05390464E8 7220000.0 0.62 1.02273078E8 8320000.0 0.73 0.9561 0.997 3131978 CMLD2_000309 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P22 compound treatment 1.02592553E8 4420000.0 0.38 9.8064321E7 4120000.0 0.36 0.5248 0.9996 3011547 CMLD2_000310 COCC#Cc1ccc(cc1)[C@@H]2N[C@@H](CC[C@H]2C)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P23 compound treatment 1.09886069E8 1.17E7 1.01 1.02420742E8 8470000.0 0.74 1.2398 0.9883 3132545 CMLD2_000311 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@@H]4CC[C@H](C)[C@H](N4C3=O)c5cccc(OC)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2109 P24 compound treatment 1.0551086E8 7340000.0 0.63 1.0258862E8 8640000.0 0.76 0.983 0.9962 3132534 CMLD2_000312 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A01 compound treatment 1.14712779E8 1.58E7 1.37 1.04841603E8 9910000.0 0.87 1.5803 0.9758 3132546 CMLD2_000313 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A02 compound treatment 1.12444562E8 1.36E7 1.17 1.04767734E8 9830000.0 0.86 1.4372 0.9885 3011548 CMLD2_000314 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A03 compound treatment 1.06409732E8 7530000.0 0.65 1.01717033E8 6780000.0 0.59 0.8798 0.9989 3130471 CMLD2_000315 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A04 compound treatment 9.7877256E7 -998000.0 -0.09 9.040594E7 -4530000.0 -0.4 -0.3413 -0.8412 3130472 CMLD2_000316 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A05 compound treatment 1.06816036E8 7940000.0 0.69 1.00260014E8 5320000.0 0.47 0.8145 0.9823 3011549 CMLD2_000317 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A06 compound treatment 1.08055038E8 9180000.0 0.79 1.01817065E8 6880000.0 0.6 0.9865 0.9908 3011597 CMLD2_000318 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A07 compound treatment 1.05277888E8 6400000.0 0.55 1.01542935E8 6610000.0 0.58 0.7999 0.9998 3130473 CMLD2_000319 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A08 compound treatment 9.3669744E7 -5210000.0 -0.45 9.0550623E7 -4380000.0 -0.38 -0.5893 -0.9969 3010878 CMLD2_000320 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A09 compound treatment 9.7578771E7 -1300000.0 -0.11 9.5485086E7 550000.0 0.05 -0.0452 -0.3707 3130474 CMLD2_000321 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A10 compound treatment 9.4771175E7 -4100000.0 -0.35 9.9206972E7 4270000.0 0.37 0.0137 0.0265 3010879 CMLD2_000322 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A11 compound treatment 1.01739032E8 2860000.0 0.25 9.8569675E7 3630000.0 0.32 0.3998 0.9923 3130475 CMLD2_000323 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A12 compound treatment 9.9383988E7 509000.0 0.04 8.9513828E7 -5420000.0 -0.47 -0.3045 -0.6389 3130476 CMLD2_000324 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A13 mock treatment 9.3764845E7 -5110000.0 -0.44 9.929067E7 4360000.0 0.38 -0.0426 -0.0731 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A14 mock treatment 1.0142353E8 2550000.0 0.22 1.01545926E8 6610000.0 0.58 0.5647 0.9123 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A15 compound treatment 1.02155807E8 3280000.0 0.28 9.9243056E7 4310000.0 0.38 0.4669 0.9901 3010880 CMLD2_000325 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A16 compound treatment 1.01637529E8 2760000.0 0.24 8.7324909E7 -7610000.0 -0.67 -0.3023 -0.4272 3130477 CMLD2_000326 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A17 compound treatment 2.9608064E7 -6.93E7 -5.98 3.5960528E7 -5.9E7 -5.16 -7.8801 -0.9973 3010881 CMLD2_000327 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A18 compound treatment 1.02438666E8 3560000.0 0.31 1.00346695E8 5410000.0 0.47 0.5525 0.9782 3130478 CMLD2_000328 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A19 compound treatment 9.832898E7 -546000.0 -0.05 9.3274187E7 -1660000.0 -0.15 -0.1362 -0.8908 3130479 CMLD2_000329 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A20 compound treatment 1.02742923E8 3870000.0 0.33 8.5870945E7 -9060000.0 -0.79 -0.3247 -0.3773 3010882 CMLD2_000330 C[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H](C)NC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A21 compound treatment 9.8902463E7 27200.0 0.0 1.02809222E8 7870000.0 0.69 0.4889 0.7095 3130480 CMLD2_000331 C[C@H]/1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C\C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A22 compound treatment 1.12134341E8 1.33E7 1.15 1.0732441E8 1.24E7 1.08 1.5765 0.9996 3010883 CMLD2_000332 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc3ccccc3)\C=C\[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A23 compound treatment 1.09440381E8 1.06E7 0.91 1.08164269E8 1.32E7 1.16 1.4639 0.9931 3130481 CMLD2_000333 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 A24 compound treatment 1.09262988E8 1.04E7 0.9 9.5820724E7 885000.0 0.08 0.6892 0.7653 3130482 CMLD2_000334 C[C@@H]1/C=C/CC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2O)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B01 compound treatment 1.12226364E8 1.34E7 1.15 1.00287543E8 5350000.0 0.47 1.1466 0.9212 3010884 CMLD2_000335 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B02 compound treatment 1.08042766E8 9170000.0 0.79 9.1009226E7 -3930000.0 -0.34 0.3169 0.3672 3130483 CMLD2_000336 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B03 compound treatment 1.06088994E8 7210000.0 0.62 1.00257445E8 5320000.0 0.47 0.7699 0.9897 3130484 CMLD2_000337 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B04 compound treatment 9.4625795E7 -4250000.0 -0.37 9.8281853E7 3350000.0 0.29 -0.0525 -0.1117 3010885 CMLD2_000338 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B05 compound treatment 1.04104653E8 5230000.0 0.45 9.7363017E7 2430000.0 0.21 0.4696 0.9408 3130485 CMLD2_000339 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B06 compound treatment 1.03122194E8 4250000.0 0.37 9.1749403E7 -3190000.0 -0.28 0.0622 0.135 3010886 CMLD2_000340 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B07 compound treatment 1.0643947E8 7560000.0 0.65 1.02000729E8 7070000.0 0.62 0.8992 0.9996 3130486 CMLD2_000341 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B08 compound treatment 8.9853717E7 -9020000.0 -0.78 9.6455914E7 1520000.0 0.13 -0.4569 -0.578 3130487 CMLD2_000342 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B09 compound treatment 9.9092636E7 217000.0 0.02 9.6939177E7 2000000.0 0.18 0.1373 0.7784 3010887 CMLD2_000343 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B10 compound treatment 9.7652866E7 -1220000.0 -0.11 8.607725E7 -8860000.0 -0.78 -0.6228 -0.7961 3130488 CMLD2_000344 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B11 compound treatment 1.00450667E8 1580000.0 0.14 9.996924E7 5030000.0 0.44 0.4077 0.8843 3010888 CMLD2_000345 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B12 compound treatment 8.7071229E7 -1.18E7 -1.02 9.4630901E7 -305000.0 -0.03 -0.7398 -0.7254 3130489 CMLD2_000346 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B13 mock treatment 1.02860609E8 3990000.0 0.34 8.7970583E7 -6960000.0 -0.61 -0.1876 -0.268 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B14 mock treatment 9.6277085E7 -2600000.0 -0.22 9.6598429E7 1660000.0 0.15 -0.0558 -0.2085 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B15 compound treatment 7.6488712E7 -2.24E7 -1.93 7.6435271E7 -1.85E7 -1.62 -2.5121 -0.9961 3130616 CMLD2_000347 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCc6ccccc6)n3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B16 compound treatment 8.9973563E7 -8900000.0 -0.77 9.1802688E7 -3130000.0 -0.27 -0.7375 -0.9035 3010889 CMLD2_000348 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B17 compound treatment 5.6921985E7 -4.2E7 -3.62 4.9383035E7 -4.56E7 -3.99 -5.3813 -0.9989 3130617 CMLD2_000349 CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B18 compound treatment 1.00455853E8 1580000.0 0.14 9.8527872E7 3590000.0 0.31 0.3188 0.9302 3010924 CMLD2_000350 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B19 compound treatment 1.05024444E8 6150000.0 0.53 1.04480987E8 9550000.0 0.84 0.9663 0.9761 3130618 CMLD2_000351 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B20 compound treatment 9.0043333E7 -8830000.0 -0.76 9.6013121E7 1080000.0 0.09 -0.4727 -0.615 3130619 CMLD2_000352 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B21 compound treatment 1.07202854E8 8330000.0 0.72 9.6068558E7 1130000.0 0.1 0.5787 0.797 3010926 CMLD2_000353 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B22 compound treatment 1.08095599E8 9220000.0 0.8 1.00672727E8 5740000.0 0.5 0.9182 0.9753 3130620 CMLD2_000354 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B23 compound treatment 1.12674883E8 1.38E7 1.19 1.0887675E8 1.39E7 1.22 1.7055 0.9999 3130621 CMLD2_000355 C[C@@H]/1COC(=O)N[C@@H](C)C(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 B24 compound treatment 9.6564489E7 -2310000.0 -0.2 1.08003891E8 1.31E7 1.14 0.6676 0.575 3010928 CMLD2_000356 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]3O[C@H](COC1=O)[C@@H](O)C=C3)[C@@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C01 compound treatment 1.07586156E8 8710000.0 0.75 1.04712697E8 9780000.0 0.86 1.1371 0.9979 3130622 CMLD2_000357 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C02 compound treatment 1.10240938E8 1.14E7 0.98 1.03592535E8 8660000.0 0.76 1.2299 0.9918 3130623 CMLD2_000358 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C03 compound treatment 9.6766895E7 -2110000.0 -0.18 1.00646422E8 5710000.0 0.5 0.2246 0.4223 3010930 CMLD2_000359 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C04 compound treatment 1.03565434E8 4690000.0 0.41 9.0085486E7 -4850000.0 -0.42 -0.0137 -0.0233 3130624 CMLD2_000360 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C05 compound treatment 1.0070393E8 1830000.0 0.16 9.7169453E7 2230000.0 0.2 0.2499 0.9944 3010931 CMLD2_000361 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C06 compound treatment 9.8929212E7 53900.0 0.0 9.7784794E7 2850000.0 0.25 0.1796 0.7202 3130625 CMLD2_000362 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C07 compound treatment 9.1630908E7 -7240000.0 -0.63 9.4080904E7 -855000.0 -0.07 -0.4953 -0.786 3130626 CMLD2_000363 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C08 compound treatment 9.7600113E7 -1280000.0 -0.11 8.2837615E7 -1.21E7 -1.06 -0.8266 -0.7765 3010932 CMLD2_000364 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C09 compound treatment 9.620878E7 -2670000.0 -0.23 9.0275145E7 -4660000.0 -0.41 -0.4513 -0.9634 3130627 CMLD2_000365 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C10 compound treatment 9.7962178E7 -913000.0 -0.08 8.9272456E7 -5660000.0 -0.5 -0.4062 -0.8094 3010933 CMLD2_000366 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C11 mock treatment 9.2281726E7 -6590000.0 -0.57 9.4382298E7 -553000.0 -0.05 -0.4369 -0.7645 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C12 mock treatment 9.6690785E7 -2180000.0 -0.19 8.534E7 -9600000.0 -0.84 -0.7272 -0.8449 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C13 compound treatment 9.818879E7 -686000.0 -0.06 9.2496601E7 -2440000.0 -0.21 -0.1929 -0.8706 3130628 CMLD2_000367 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C14 compound treatment 9.4852243E7 -4020000.0 -0.35 9.49814E7 45800.0 0.0 -0.2429 -0.6989 3010934 CMLD2_000368 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C15 mock treatment 9.0525964E7 -8350000.0 -0.72 9.6754206E7 1820000.0 0.16 -0.3974 -0.5381 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C16 mock treatment 9.9178284E7 303000.0 0.03 8.5434085E7 -9500000.0 -0.83 -0.5695 -0.6845 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C17 compound treatment 9.7190742E7 -1680000.0 -0.15 9.4393965E7 -542000.0 -0.05 -0.1364 -0.8914 3130629 CMLD2_000369 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C18 compound treatment 9.7346015E7 -1530000.0 -0.13 1.01994713E8 7060000.0 0.62 0.3435 0.5436 3130630 CMLD2_000370 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C19 compound treatment 1.02470219E8 3590000.0 0.31 1.00460097E8 5520000.0 0.48 0.5614 0.9771 3010935 CMLD2_000371 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C20 compound treatment 1.00516549E8 1640000.0 0.14 9.1815543E7 -3120000.0 -0.27 -0.0928 -0.3018 3130631 CMLD2_000372 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C21 compound treatment 9.9031208E7 156000.0 0.01 1.01773762E8 6840000.0 0.6 0.4327 0.7228 3010936 CMLD2_000373 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C22 compound treatment 1.06552491E8 7680000.0 0.66 1.01745894E8 6810000.0 0.6 0.8903 0.9986 3130632 CMLD2_000374 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C23 compound treatment 1.10730808E8 1.19E7 1.02 1.02385544E8 7450000.0 0.65 1.1851 0.9762 3130633 CMLD2_000375 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 C24 compound treatment 1.11985155E8 1.31E7 1.13 9.8809327E7 3870000.0 0.34 1.0404 0.8802 3010937 CMLD2_000376 C[C@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D01 compound treatment 9.7493692E7 -1380000.0 -0.12 1.05705425E8 1.08E7 0.94 0.5821 0.6127 3130634 CMLD2_000377 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D02 compound treatment 1.02868459E8 3990000.0 0.34 8.8720773E7 -6210000.0 -0.54 -0.1407 -0.2185 3010938 CMLD2_000378 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D03 compound treatment 1.08257882E8 9380000.0 0.81 1.01745306E8 6810000.0 0.6 0.9945 0.9886 3130635 CMLD2_000379 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D04 compound treatment 1.00143815E8 1270000.0 0.11 9.5779481E7 844000.0 0.07 0.1297 0.9816 3130759 CMLD2_000380 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D05 compound treatment 9.2132142E7 -6740000.0 -0.58 9.6981725E7 2050000.0 0.18 -0.2852 -0.4681 3010939 CMLD2_000381 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D06 compound treatment 9.9759571E7 884000.0 0.08 8.4459673E7 -1.05E7 -0.92 -0.5943 -0.646 3130760 CMLD2_000382 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D07 compound treatment 1.02325843E8 3450000.0 0.3 9.6919236E7 1980000.0 0.17 0.3335 0.9669 3130761 CMLD2_000383 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D08 compound treatment 9.439227E7 -4480000.0 -0.39 9.4196026E7 -740000.0 -0.06 -0.3196 -0.814 3130762 CMLD2_000384 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D09 compound treatment 9.1641267E7 -7230000.0 -0.62 9.6185819E7 1250000.0 0.11 -0.3644 -0.5745 3010981 CMLD2_000385 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D10 compound treatment 9.6411928E7 -2460000.0 -0.21 8.6620117E7 -8320000.0 -0.73 -0.665 -0.8771 3130763 CMLD2_000386 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D11 mock treatment 1.01828317E8 2950000.0 0.26 9.9933569E7 5000000.0 0.44 0.4897 0.967 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D12 mock treatment 8.748731E7 -1.14E7 -0.98 9.4853665E7 -81900.0 -0.01 -0.7006 -0.7122 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D13 compound treatment 9.9827707E7 952000.0 0.08 9.8817417E7 3880000.0 0.34 0.2984 0.8537 3130764 CMLD2_000387 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D14 compound treatment 9.8218247E7 -657000.0 -0.06 8.3958492E7 -1.1E7 -0.96 -0.7194 -0.7476 3010983 CMLD2_000388 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D15 mock treatment 1.02482205E8 3610000.0 0.31 9.6709111E7 1770000.0 0.16 0.33 0.9482 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D16 mock treatment 8.9983561E7 -8890000.0 -0.77 9.585625E7 921000.0 0.08 -0.4861 -0.6295 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D17 compound treatment 9.4583654E7 -4290000.0 -0.37 9.6334984E7 1400000.0 0.12 -0.1755 -0.4496 3130765 CMLD2_000389 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D18 compound treatment 1.02753347E8 3880000.0 0.33 8.9885227E7 -5050000.0 -0.44 -0.0757 -0.1365 3010984 CMLD2_000390 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D19 compound treatment 1.04358166E8 5480000.0 0.47 1.01013595E8 6080000.0 0.53 0.711 0.9983 3130766 CMLD2_000391 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D20 compound treatment 9.5296173E7 -3580000.0 -0.31 9.81238E7 3190000.0 0.28 -0.0213 -0.0511 3010985 CMLD2_000392 CO[C@@H]1/C=C/CC(=O)N[C@@H](C)C(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D21 compound treatment 1.07017666E8 8140000.0 0.7 1.05084451E8 1.01E7 0.89 1.1253 0.9933 3130767 CMLD2_000393 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D22 compound treatment 1.05328747E8 6450000.0 0.56 9.3039979E7 -1900000.0 -0.17 0.2768 0.476 3130768 CMLD2_000394 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D23 compound treatment 1.12856431E8 1.4E7 1.21 1.0816972E8 1.32E7 1.16 1.6729 0.9998 3130619 CMLD2_000395 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 D24 compound treatment 1.02287314E8 3410000.0 0.29 1.06749715E8 1.18E7 1.03 0.9395 0.8738 3010986 CMLD2_000396 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E01 mock treatment 1.11889139E8 1.3E7 1.12 1.02067419E8 7130000.0 0.62 1.2362 0.9615 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E02 mock treatment 1.09785574E8 1.09E7 0.94 9.614217E7 1210000.0 0.11 0.741 0.7815 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E03 compound treatment 1.04356551E8 5480000.0 0.47 9.7836916E7 2900000.0 0.25 0.5143 0.9574 3130769 CMLD2_000397 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E04 compound treatment 1.00168224E8 1290000.0 0.11 9.129358E7 -3640000.0 -0.32 -0.1464 -0.4335 3130770 CMLD2_000398 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E05 compound treatment 9.9061437E7 186000.0 0.02 9.646869E7 1530000.0 0.13 0.1062 0.7862 3010987 CMLD2_000399 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E06 compound treatment 9.5871451E7 -3000000.0 -0.26 8.8521195E7 -6410000.0 -0.56 -0.5804 -0.9385 3130771 CMLD2_000400 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E07 compound treatment 9.8138933E7 -736000.0 -0.06 9.3414635E7 -1520000.0 -0.13 -0.1391 -0.9429 3130772 CMLD2_000401 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E08 compound treatment 9.6048412E7 -2830000.0 -0.24 8.9301915E7 -5630000.0 -0.49 -0.5213 -0.9475 3010988 CMLD2_000402 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E09 mock treatment 9.2456059E7 -6420000.0 -0.55 9.1954252E7 -2980000.0 -0.26 -0.5765 -0.9409 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E10 mock treatment 9.1421848E7 -7450000.0 -0.64 8.7803507E7 -7130000.0 -0.62 -0.8966 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E11 compound treatment 9.7860803E7 -1010000.0 -0.09 7.5980544E7 -1.9E7 -1.66 -1.235 -0.7434 3130773 CMLD2_000403 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E12 compound treatment 9.0998873E7 -7880000.0 -0.68 8.4124088E7 -1.08E7 -0.95 -1.1501 -0.9869 3010989 CMLD2_000404 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E13 compound treatment 9.5427097E7 -3450000.0 -0.3 9.3156813E7 -1780000.0 -0.16 -0.3207 -0.9542 3130774 CMLD2_000405 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E14 compound treatment 9.2952397E7 -5920000.0 -0.51 9.2239717E7 -2700000.0 -0.24 -0.5286 -0.9382 3130775 CMLD2_000406 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E15 compound treatment 9.6611079E7 -2260000.0 -0.2 9.1530377E7 -3410000.0 -0.3 -0.349 -0.9791 3010990 CMLD2_000407 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCC(C)C)n3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E16 compound treatment 9.5386751E7 -3490000.0 -0.3 9.5785807E7 850000.0 0.07 -0.1604 -0.5169 3130776 CMLD2_000408 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E17 mock treatment 9.9515002E7 640000.0 0.06 1.04053948E8 9120000.0 0.8 0.6034 0.7543 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E18 mock treatment 1.0277702E8 3900000.0 0.34 1.02923223E8 7990000.0 0.7 0.7326 0.944 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E19 compound treatment 1.02328136E8 3450000.0 0.3 1.01327551E8 6390000.0 0.56 0.6064 0.9566 3010991 CMLD2_000409 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E20 compound treatment 9.9320996E7 446000.0 0.04 9.8088896E7 3150000.0 0.28 0.2224 0.798 3130777 CMLD2_000410 C[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E21 compound treatment 1.05995366E8 7120000.0 0.61 1.01784434E8 6850000.0 0.6 0.8587 0.9999 3130778 CMLD2_000411 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E22 compound treatment 1.03529087E8 4650000.0 0.4 1.014484E8 6510000.0 0.57 0.6873 0.9854 3010992 CMLD2_000412 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E23 compound treatment 1.06754608E8 7880000.0 0.68 1.03736027E8 8800000.0 0.77 1.0258 0.9981 3130904 CMLD2_000413 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C)NS(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 E24 compound treatment 1.10185983E8 1.13E7 0.98 1.04422594E8 9490000.0 0.83 1.2779 0.9967 3130905 CMLD2_000414 CO[C@@H]1COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F01 mock treatment 1.09811249E8 1.09E7 0.94 1.02328141E8 7390000.0 0.65 1.1254 0.983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F02 mock treatment 1.05850292E8 6980000.0 0.6 9.672733E7 1790000.0 0.16 0.5369 0.8624 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F03 compound treatment 1.01155595E8 2280000.0 0.2 1.01196375E8 6260000.0 0.55 0.5267 0.9046 3010993 CMLD2_000415 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F04 compound treatment 9.7151201E7 -1720000.0 -0.15 8.8502935E7 -6430000.0 -0.56 -0.5034 -0.8644 3130906 CMLD2_000416 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F05 compound treatment 1.0025919E8 1380000.0 0.12 9.7490359E7 2550000.0 0.22 0.2426 0.957 3130907 CMLD2_000417 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F06 compound treatment 9.4179532E7 -4700000.0 -0.41 9.2333454E7 -2600000.0 -0.23 -0.4478 -0.9628 3011036 CMLD2_000418 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F07 compound treatment 9.8920358E7 45100.0 0.0 9.7703441E7 2770000.0 0.24 0.174 0.7184 3130908 CMLD2_000419 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F08 compound treatment 9.4613119E7 -4260000.0 -0.37 9.2322663E7 -2610000.0 -0.23 -0.422 -0.9738 3130909 CMLD2_000420 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F09 mock treatment 9.5312863E7 -3560000.0 -0.31 9.6697498E7 1760000.0 0.15 -0.1085 -0.3154 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F10 mock treatment 9.1432988E7 -7440000.0 -0.64 8.9984302E7 -4950000.0 -0.43 -0.7609 -0.9816 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F11 compound treatment 9.7610754E7 -1260000.0 -0.11 9.6210883E7 1280000.0 0.11 0.0017 0.0108 3011038 CMLD2_000421 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F12 compound treatment 9.2983057E7 -5890000.0 -0.51 9.216774E7 -2770000.0 -0.24 -0.5311 -0.9424 3130910 CMLD2_000422 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F13 compound treatment 9.9513288E7 638000.0 0.06 9.6224953E7 1290000.0 0.11 0.1188 0.9457 3011039 CMLD2_000423 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F14 compound treatment 9.366799E7 -5210000.0 -0.45 9.3394972E7 -1540000.0 -0.13 -0.4134 -0.8804 3130911 CMLD2_000424 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F15 compound treatment 9.564512E7 -3230000.0 -0.28 9.5535483E7 600000.0 0.05 -0.1602 -0.5641 3130912 CMLD2_000425 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC\C=C(/C)\CCC=C(C)C)n3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F16 compound treatment 9.2415763E7 -6460000.0 -0.56 9.6210135E7 1270000.0 0.11 -0.3156 -0.5548 3011040 CMLD2_000426 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F17 mock treatment 1.02679321E8 3800000.0 0.33 1.02663589E8 7730000.0 0.68 0.7106 0.945 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F18 mock treatment 1.01749437E8 2870000.0 0.25 1.02831268E8 7900000.0 0.69 0.6642 0.9045 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F19 compound treatment 1.00841291E8 1970000.0 0.17 1.00571336E8 5640000.0 0.49 0.4688 0.8988 3011041 CMLD2_000427 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F20 compound treatment 1.00099323E8 1220000.0 0.11 9.788941E7 2950000.0 0.26 0.2576 0.9222 3130913 CMLD2_000428 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F21 compound treatment 1.04947288E8 6070000.0 0.52 1.02602998E8 7670000.0 0.67 0.8453 0.9926 3130914 CMLD2_000429 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F22 compound treatment 1.00279094E8 1400000.0 0.12 9.8606424E7 3670000.0 0.32 0.3129 0.9112 3011043 CMLD2_000430 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC1=O)[C@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F23 compound treatment 1.06547444E8 7670000.0 0.66 1.04493666E8 9560000.0 0.84 1.0601 0.9933 3130915 CMLD2_000431 CO[C@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 F24 compound treatment 1.07405772E8 8530000.0 0.74 1.0267359E8 7740000.0 0.68 0.9999 0.9991 3011044 CMLD2_000432 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G01 compound treatment 1.07084275E8 8210000.0 0.71 9.8743261E7 3810000.0 0.33 0.737 0.9407 3130916 CMLD2_000433 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G02 compound treatment 1.07575763E8 8700000.0 0.75 1.00076526E8 5140000.0 0.45 0.8495 0.9699 3130917 CMLD2_000434 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G03 mock treatment 1.06801734E8 7930000.0 0.68 9.8484349E7 3550000.0 0.31 0.7037 0.9361 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G04 mock treatment 1.00212162E8 1340000.0 0.12 9.4820528E7 -115000.0 -0.01 0.0745 0.643 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G05 compound treatment 9.4296674E7 -4580000.0 -0.4 8.9729375E7 -5210000.0 -0.46 -0.6018 -0.9975 3011046 CMLD2_000435 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G06 compound treatment 9.4254825E7 -4620000.0 -0.4 9.4260703E7 -675000.0 -0.06 -0.324 -0.803 3130918 CMLD2_000436 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G07 compound treatment 9.8321393E7 -554000.0 -0.05 9.8086715E7 3150000.0 0.28 0.1612 0.5758 3130919 CMLD2_000437 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G08 compound treatment 9.4033734E7 -4840000.0 -0.42 9.372161E7 -1210000.0 -0.11 -0.3708 -0.8595 3011047 CMLD2_000438 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G09 compound treatment 8.9710967E7 -9160000.0 -0.79 9.6978901E7 2040000.0 0.18 -0.4333 -0.5339 3130920 CMLD2_000439 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G10 compound treatment 8.9706873E7 -9170000.0 -0.79 9.047892E7 -4460000.0 -0.39 -0.8358 -0.9468 3011048 CMLD2_000440 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G11 compound treatment 9.547167E7 -3400000.0 -0.29 9.2036227E7 -2900000.0 -0.25 -0.3873 -0.9973 3130921 CMLD2_000441 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G12 compound treatment 9.4043061E7 -4830000.0 -0.42 8.9124753E7 -5810000.0 -0.51 -0.6547 -0.9952 3131048 CMLD2_000442 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G13 compound treatment 9.3405279E7 -5470000.0 -0.47 9.2997887E7 -1940000.0 -0.17 -0.454 -0.9044 3011049 CMLD2_000443 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G14 compound treatment 9.0522245E7 -8350000.0 -0.72 9.3151035E7 -1780000.0 -0.16 -0.6206 -0.8407 3131049 CMLD2_000444 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(CC)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G15 compound treatment 8.7162614E7 -1.17E7 -1.01 9.3355672E7 -1580000.0 -0.14 -0.8131 -0.7963 3011050 CMLD2_000445 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCCCC#C)n3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G16 compound treatment 4.9920004E7 -4.9E7 -4.23 5.0669313E7 -4.43E7 -3.87 -5.7293 -0.999 3131050 CMLD2_000446 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G17 compound treatment 1.00270584E8 1400000.0 0.12 9.5889719E7 954000.0 0.08 0.1443 0.9839 3131051 CMLD2_000447 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G18 compound treatment 9.4778394E7 -4100000.0 -0.35 9.7004423E7 2070000.0 0.18 -0.1222 -0.3074 3011052 CMLD2_000448 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G19 mock treatment 1.02858026E8 3980000.0 0.34 9.4959882E7 24300.0 0.0 0.2447 0.7115 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G20 mock treatment 1.02795849E8 3920000.0 0.34 1.00449558E8 5510000.0 0.48 0.5807 0.985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G21 compound treatment 1.03444732E8 4570000.0 0.39 9.6014026E7 1080000.0 0.09 0.3458 0.8522 3131052 CMLD2_000449 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C\C=C\[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G22 compound treatment 1.05160031E8 6280000.0 0.54 1.01640761E8 6710000.0 0.59 0.7988 0.9992 3011053 CMLD2_000450 C[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G23 compound treatment 1.08101925E8 9230000.0 0.8 1.00862818E8 5930000.0 0.52 0.9303 0.9784 3131053 CMLD2_000451 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@@H]3CCCN3C1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 G24 compound treatment 1.08942724E8 1.01E7 0.87 1.05504526E8 1.06E7 0.92 1.2689 0.9995 3131054 CMLD2_000452 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H01 compound treatment 1.11052424E8 1.22E7 1.05 1.05677971E8 1.07E7 0.94 1.4085 0.9984 3011098 CMLD2_000453 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H02 compound treatment 1.06704117E8 7830000.0 0.68 9.2613475E7 -2320000.0 -0.2 0.3344 0.4737 3131055 CMLD2_000454 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H03 mock treatment 1.04362819E8 5490000.0 0.47 9.7537444E7 2600000.0 0.23 0.4962 0.9436 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H04 mock treatment 9.785831E7 -1020000.0 -0.09 9.2973866E7 -1960000.0 -0.17 -0.1835 -0.9516 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H05 compound treatment 9.8301876E7 -573000.0 -0.05 9.6279151E7 1340000.0 0.12 0.0481 0.3772 3131056 CMLD2_000455 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H06 compound treatment 9.1903944E7 -6970000.0 -0.6 8.8220507E7 -6720000.0 -0.59 -0.8413 -0.9999 3011099 CMLD2_000456 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H07 compound treatment 9.8958021E7 82700.0 0.01 9.840483E7 3470000.0 0.3 0.2197 0.7235 3131057 CMLD2_000457 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H08 compound treatment 9.3678152E7 -5200000.0 -0.45 9.1579381E7 -3360000.0 -0.29 -0.5251 -0.9789 3011100 CMLD2_000458 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H09 compound treatment 9.9591292E7 716000.0 0.06 9.5018228E7 82700.0 0.01 0.0488 0.7845 3131058 CMLD2_000459 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H10 compound treatment 8.8552329E7 -1.03E7 -0.89 8.8801508E7 -6130000.0 -0.54 -1.0101 -0.9705 3131059 CMLD2_000460 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H11 compound treatment 9.637165E7 -2500000.0 -0.22 9.4485887E7 -450000.0 -0.04 -0.1807 -0.8223 3011101 CMLD2_000461 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H12 compound treatment 9.6901201E7 -1970000.0 -0.17 9.1324287E7 -3610000.0 -0.32 -0.344 -0.9581 3131060 CMLD2_000462 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H13 compound treatment 9.6886679E7 -1990000.0 -0.17 9.5705755E7 770000.0 0.07 -0.0738 -0.3999 3131061 CMLD2_000463 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H14 compound treatment 9.1562085E7 -7310000.0 -0.63 8.6995014E7 -7940000.0 -0.69 -0.938 -0.9989 3011102 CMLD2_000464 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H15 compound treatment 9.2556334E7 -6320000.0 -0.55 9.1194345E7 -3740000.0 -0.33 -0.6174 -0.9701 3131062 CMLD2_000465 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC[C@@H](O)COCc6ccco6)n3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H16 compound treatment 9.1048166E7 -7830000.0 -0.68 8.8536392E7 -6400000.0 -0.56 -0.874 -0.9956 3011103 CMLD2_000466 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H17 compound treatment 1.02081053E8 3210000.0 0.28 9.9707241E7 4770000.0 0.42 0.4911 0.9801 3131063 CMLD2_000467 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H18 compound treatment 9.6973088E7 -1900000.0 -0.16 9.2894745E7 -2040000.0 -0.18 -0.2425 -0.9991 3011104 CMLD2_000468 CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H19 mock treatment 1.05509691E8 6630000.0 0.57 9.8941266E7 4010000.0 0.35 0.6531 0.9722 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H20 mock treatment 1.00272196E8 1400000.0 0.12 9.5265352E7 330000.0 0.03 0.1057 0.8522 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H21 compound treatment 1.09192617E8 1.03E7 0.89 9.1483521E7 -3450000.0 -0.3 0.4165 0.4426 3131064 CMLD2_000469 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H22 compound treatment 1.01959468E8 3080000.0 0.27 9.8830762E7 3900000.0 0.34 0.4294 0.9926 3011105 CMLD2_000470 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H23 compound treatment 1.09430998E8 1.06E7 0.91 1.02264961E8 7330000.0 0.64 1.0983 0.9852 3131065 CMLD2_000471 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 H24 compound treatment 1.09270475E8 1.04E7 0.9 1.01856151E8 6920000.0 0.61 1.0632 0.9816 3131066 CMLD2_000472 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I01 compound treatment 1.11506413E8 1.26E7 1.09 1.03223829E8 8290000.0 0.73 1.2844 0.9803 3011106 CMLD2_000473 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I02 compound treatment 1.06934561E8 8060000.0 0.7 9.9461679E7 4530000.0 0.4 0.7723 0.9643 3131067 CMLD2_000474 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I03 compound treatment 1.02046749E8 3170000.0 0.27 9.894003E7 4000000.0 0.35 0.4415 0.9926 3131183 CMLD2_000475 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I04 compound treatment 9.6544681E7 -2330000.0 -0.2 9.312024E7 -1820000.0 -0.16 -0.2547 -0.9931 3011108 CMLD2_000476 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I05 mock treatment 9.9148981E7 274000.0 0.02 9.7094974E7 2160000.0 0.19 0.1504 0.7894 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I06 mock treatment 9.6597965E7 -2280000.0 -0.2 9.19951E7 -2940000.0 -0.26 -0.3211 -0.9912 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I07 compound treatment 9.5857522E7 -3020000.0 -0.26 9.7251073E7 2320000.0 0.2 -0.041 -0.1242 3131184 CMLD2_000477 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I08 compound treatment 9.4064173E7 -4810000.0 -0.42 9.2164415E7 -2770000.0 -0.24 -0.4653 -0.9671 3011109 CMLD2_000478 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I09 compound treatment 9.1712187E7 -7160000.0 -0.62 9.5123634E7 188000.0 0.02 -0.4258 -0.6881 3131185 CMLD2_000479 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I10 compound treatment 8.5407932E7 -1.35E7 -1.16 8.7756735E7 -7180000.0 -0.63 -1.2668 -0.9582 3131186 CMLD2_000480 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I11 compound treatment 9.1602651E7 -7270000.0 -0.63 9.4291956E7 -644000.0 -0.06 -0.484 -0.7674 3011110 CMLD2_000481 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I12 compound treatment 8.8783033E7 -1.01E7 -0.87 8.9877658E7 -5060000.0 -0.44 -0.9294 -0.9506 3131187 CMLD2_000482 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I13 compound treatment 9.506853E7 -3810000.0 -0.33 9.5048612E7 113000.0 0.01 -0.2255 -0.6855 3131188 CMLD2_000483 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I14 compound treatment 9.1952341E7 -6920000.0 -0.6 9.4456177E7 -479000.0 -0.04 -0.4525 -0.7549 3011112 CMLD2_000484 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I15 compound treatment 9.560338E7 -3270000.0 -0.28 9.5104551E7 169000.0 0.01 -0.1894 -0.6692 3131189 CMLD2_000485 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCc5ccccc5)n2c1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I16 compound treatment 4.2984239E7 -5.59E7 -4.83 4.4457619E7 -5.05E7 -4.42 -6.5373 -0.999 3011154 CMLD2_000486 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I17 compound treatment 9.7692432E7 -1180000.0 -0.1 9.6517967E7 1580000.0 0.14 0.0257 0.1492 3131190 CMLD2_000487 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I18 compound treatment 9.3040678E7 -5830000.0 -0.5 9.6452866E7 1520000.0 0.13 -0.2624 -0.5036 3010995 CMLD2_000488 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I19 compound treatment 8.8279788E7 -1.06E7 -0.92 8.1905447E7 -1.3E7 -1.14 -1.4535 -0.9941 3131191 CMLD2_000489 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I20 compound treatment 9.9444727E7 569000.0 0.05 9.7379063E7 2440000.0 0.21 0.186 0.8476 3131192 CMLD2_000490 C[C@H]/1COC(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I21 mock treatment 1.0165616E8 2780000.0 0.24 1.00984353E8 6050000.0 0.53 0.5442 0.9361 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I22 mock treatment 1.03696569E8 4820000.0 0.42 1.0046829E8 5530000.0 0.48 0.6368 0.9972 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I23 compound treatment 1.00256391E8 1380000.0 0.12 1.01758373E8 6820000.0 0.6 0.5066 0.8319 3131193 CMLD2_000491 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 I24 compound treatment 1.01854321E8 2980000.0 0.26 1.02008833E8 7070000.0 0.62 0.6197 0.9244 3011157 CMLD2_000492 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J01 compound treatment 1.06582517E8 7710000.0 0.67 1.05771527E8 1.08E7 0.95 1.1413 0.985 3131194 CMLD2_000493 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J02 compound treatment 1.05403768E8 6530000.0 0.56 1.00388017E8 5450000.0 0.48 0.7361 0.9966 3011158 CMLD2_000494 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J03 compound treatment 1.00213267E8 1340000.0 0.12 1.00273808E8 5340000.0 0.47 0.4121 0.8562 3131195 CMLD2_000495 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J04 compound treatment 9.7692697E7 -1180000.0 -0.1 9.1363772E7 -3570000.0 -0.31 -0.2933 -0.8918 3011159 CMLD2_000496 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J05 mock treatment 1.01399333E8 2520000.0 0.22 9.7901421E7 2970000.0 0.26 0.3377 0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J06 mock treatment 9.1730023E7 -7150000.0 -0.62 9.3188647E7 -1750000.0 -0.15 -0.5445 -0.8564 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J07 compound treatment 9.9032757E7 157000.0 0.01 9.6222704E7 1290000.0 0.11 0.0893 0.7868 3131196 CMLD2_000497 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J08 compound treatment 8.9864893E7 -9010000.0 -0.78 9.2976594E7 -1960000.0 -0.17 -0.6715 -0.8427 3131197 CMLD2_000498 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J09 compound treatment 9.3435442E7 -5440000.0 -0.47 9.588067E7 945000.0 0.08 -0.2737 -0.5738 3011160 CMLD2_000499 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J10 compound treatment 8.8054496E7 -1.08E7 -0.93 8.9559705E7 -5380000.0 -0.47 -0.9936 -0.9495 3131198 CMLD2_000500 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J11 compound treatment 9.5247607E7 -3630000.0 -0.31 9.4707427E7 -228000.0 -0.02 -0.2357 -0.7506 3011161 CMLD2_000501 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J12 compound treatment 8.779384E7 -1.11E7 -0.96 9.0622848E7 -4310000.0 -0.38 -0.9437 -0.9172 3131199 CMLD2_000502 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J13 compound treatment 9.3761352E7 -5110000.0 -0.44 9.5258204E7 323000.0 0.03 -0.2924 -0.6606 3131200 CMLD2_000503 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J14 compound treatment 9.0466923E7 -8410000.0 -0.73 9.3611503E7 -1320000.0 -0.12 -0.5955 -0.8097 3011162 CMLD2_000504 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J15 compound treatment 9.6582358E7 -2290000.0 -0.2 9.7563124E7 2630000.0 0.23 0.0226 0.0744 3131201 CMLD2_000505 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J16 compound treatment 9.1007189E7 -7870000.0 -0.68 9.1763868E7 -3170000.0 -0.28 -0.6768 -0.922 3011163 CMLD2_000506 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J17 compound treatment 9.5014611E7 -3860000.0 -0.33 9.8335928E7 3400000.0 0.3 -0.0254 -0.0567 3131202 CMLD2_000507 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J18 compound treatment 9.3256027E7 -5620000.0 -0.49 9.403114E7 -904000.0 -0.08 -0.3992 -0.8117 3011164 CMLD2_000508 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J19 compound treatment 1.00657654E8 1780000.0 0.15 1.00314897E8 5380000.0 0.47 0.4418 0.8919 3131320 CMLD2_000509 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J20 compound treatment 9.6524244E7 -2350000.0 -0.2 9.5873236E7 938000.0 0.08 -0.0856 -0.3907 3131321 CMLD2_000510 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J21 mock treatment 1.04992217E8 6120000.0 0.53 1.02199466E8 7260000.0 0.64 0.8231 0.9958 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J22 mock treatment 9.9327074E7 452000.0 0.04 9.5583698E7 648000.0 0.06 0.0677 0.9833 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J23 compound treatment 9.4551196E7 -4320000.0 -0.37 1.0204649E8 7110000.0 0.62 0.176 0.2424 1952481 CMLD2_000511 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 J24 compound treatment 9.74854E7 -1390000.0 -0.12 1.00612432E8 5680000.0 0.5 0.2664 0.5212 3131322 CMLD2_000512 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K01 compound treatment 1.056358E8 6760000.0 0.58 8.5299163E7 -9640000.0 -0.84 -0.1834 -0.1788 3131323 CMLD2_000513 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K02 compound treatment 1.03173782E8 4300000.0 0.37 7.8778227E7 -1.62E7 -1.41 -0.7374 -0.5044 3011055 CMLD2_000514 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K03 compound treatment 1.07334822E8 8460000.0 0.73 1.0223085E8 7300000.0 0.64 0.9681 0.9977 3131324 CMLD2_000515 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K04 compound treatment 9.807765E7 -798000.0 -0.07 9.0173343E7 -4760000.0 -0.42 -0.3434 -0.813 3011057 CMLD2_000516 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K05 compound treatment 1.00914866E8 2040000.0 0.18 1.02780767E8 7850000.0 0.69 0.6101 0.8607 3131325 CMLD2_000517 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K06 compound treatment 9.8798993E7 -76300.0 -0.01 9.6350434E7 1410000.0 0.12 0.0829 0.6685 3131326 CMLD2_000518 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K07 mock treatment 9.824104E7 -634000.0 -0.05 1.00278367E8 5340000.0 0.47 0.2919 0.62 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K08 mock treatment 8.6334608E7 -1.25E7 -1.08 9.490393E7 -31600.0 0.0 -0.7679 -0.7089 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K09 compound treatment 9.6228854E7 -2650000.0 -0.23 9.6762544E7 1830000.0 0.16 -0.0486 -0.1741 3011058 CMLD2_000519 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K10 compound treatment 8.7774603E7 -1.11E7 -0.96 8.5839752E7 -9100000.0 -0.8 -1.2409 -0.9957 3131327 CMLD2_000520 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K11 compound treatment 8.9790011E7 -9090000.0 -0.78 8.7904764E7 -7030000.0 -0.62 -0.99 -0.9928 3011059 CMLD2_000521 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K12 compound treatment 8.755436E7 -1.13E7 -0.98 9.4331843E7 -604000.0 -0.05 -0.7288 -0.7442 3131328 CMLD2_000522 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K13 compound treatment 8.8008081E7 -1.09E7 -0.94 9.7756232E7 2820000.0 0.25 -0.4892 -0.504 3131329 CMLD2_000523 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K14 compound treatment 9.2696654E7 -6180000.0 -0.53 9.2912064E7 -2020000.0 -0.18 -0.5026 -0.8938 3011060 CMLD2_000524 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(c6ccccc6)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K15 mock treatment 1.00099784E8 1220000.0 0.11 8.3575236E7 -1.14E7 -0.99 -0.6282 -0.6283 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K16 mock treatment 9.4108521E7 -4770000.0 -0.41 8.3234571E7 -1.17E7 -1.02 -1.0152 -0.9198 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K17 compound treatment 1.00284031E8 1410000.0 0.12 9.689586E7 1960000.0 0.17 0.2074 0.9858 3131330 CMLD2_000525 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K18 compound treatment 9.4430113E7 -4450000.0 -0.38 9.175635E7 -3180000.0 -0.28 -0.4682 -0.9875 3011061 CMLD2_000526 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K19 compound treatment 1.02384402E8 3510000.0 0.3 1.02727416E8 7790000.0 0.68 0.6965 0.9334 3131331 CMLD2_000527 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K20 compound treatment 1.01387823E8 2510000.0 0.22 9.3636818E7 -1300000.0 -0.11 0.0731 0.2983 3011062 CMLD2_000528 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K21 compound treatment 1.05313647E8 6440000.0 0.56 1.04391334E8 9460000.0 0.83 0.9784 0.9813 3011070 CMLD2_000529 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K22 compound treatment 1.03891185E8 5020000.0 0.43 9.9264176E7 4330000.0 0.38 0.5742 0.9978 3011072 CMLD2_000530 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)COC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K23 mock treatment 1.08149305E8 9270000.0 0.8 9.9064961E7 4130000.0 0.36 0.822 0.9353 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 K24 mock treatment 9.8206482E7 -669000.0 -0.06 9.7098618E7 2160000.0 0.19 0.093 0.4699 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L01 compound treatment 9.9272084E7 397000.0 0.03 9.0439671E7 -4500000.0 -0.39 -0.254 -0.6431 3131332 CMLD2_000531 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L02 compound treatment 1.00872919E8 2000000.0 0.17 7.4129393E7 -2.08E7 -1.82 -1.1656 -0.6373 3131333 CMLD2_000532 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L03 compound treatment 1.083068E8 9430000.0 0.81 9.8046045E7 3110000.0 0.27 0.7685 0.8948 3011074 CMLD2_000533 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L04 compound treatment 9.7636101E7 -1240000.0 -0.11 9.5933392E7 998000.0 0.09 -0.0139 -0.1009 3131334 CMLD2_000534 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L05 compound treatment 1.05028225E8 6150000.0 0.53 9.5510781E7 575000.0 0.05 0.4114 0.7706 3131335 CMLD2_000535 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L06 compound treatment 9.2290684E7 -6580000.0 -0.57 9.7577975E7 2640000.0 0.23 -0.2386 -0.3887 3011078 CMLD2_000536 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L07 mock treatment 1.0038184E8 1510000.0 0.13 1.0043724E8 5500000.0 0.48 0.4325 0.8671 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L08 mock treatment 9.3801879E7 -5070000.0 -0.44 9.2061143E7 -2870000.0 -0.25 -0.4877 -0.9653 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L09 compound treatment 8.987263E7 -9000000.0 -0.78 9.3776145E7 -1160000.0 -0.1 -0.6216 -0.7927 3011128 CMLD2_000537 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L10 compound treatment 9.0729969E7 -8150000.0 -0.7 8.7924647E7 -7010000.0 -0.61 -0.9313 -0.9977 3131336 CMLD2_000538 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L11 compound treatment 9.7564833E7 -1310000.0 -0.11 9.3919553E7 -1020000.0 -0.09 -0.1429 -0.9929 3011131 CMLD2_000539 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L12 compound treatment 8.72096E7 -1.17E7 -1.01 9.3368827E7 -1570000.0 -0.14 -0.8094 -0.796 3131337 CMLD2_000540 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L13 compound treatment 9.6003005E7 -2870000.0 -0.25 9.6374506E7 1440000.0 0.13 -0.0864 -0.3105 3131338 CMLD2_000541 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L14 compound treatment 8.5091598E7 -1.38E7 -1.19 8.8993063E7 -5940000.0 -0.52 -1.2096 -0.931 3011134 CMLD2_000542 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L15 mock treatment 1.02243141E8 3370000.0 0.29 7.463212E7 -2.03E7 -1.78 -1.0508 -0.5836 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L16 mock treatment 9.8111067E7 -764000.0 -0.07 7.8386629E7 -1.65E7 -1.45 -1.0708 -0.7386 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L17 compound treatment 9.5205093E7 -3670000.0 -0.32 9.7381528E7 2450000.0 0.21 -0.0728 -0.1903 3131454 CMLD2_000543 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L18 compound treatment 8.07085E7 -1.82E7 -1.57 7.8072116E7 -1.69E7 -1.48 -2.1531 -0.9995 3011136 CMLD2_000544 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]4[C@H]([C@H](O)[C@@H]5O[C@@H]5C4=O)n3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L19 compound treatment 1.03326664E8 4450000.0 0.38 1.00503745E8 5570000.0 0.49 0.6164 0.9931 3131455 CMLD2_000545 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L20 compound treatment 9.9674817E7 800000.0 0.07 9.9656743E7 4720000.0 0.41 0.341 0.814 3131456 CMLD2_000546 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2)NS(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L21 compound treatment 1.05473165E8 6600000.0 0.57 9.5807744E7 872000.0 0.08 0.4569 0.7947 3011138 CMLD2_000547 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L22 compound treatment 1.03164501E8 4290000.0 0.37 1.01552739E8 6620000.0 0.58 0.6715 0.9767 3131457 CMLD2_000548 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L23 mock treatment 1.05085295E8 6210000.0 0.54 9.9373811E7 4440000.0 0.39 0.6539 0.9874 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 L24 mock treatment 1.11056661E8 1.22E7 1.05 1.03381379E8 8450000.0 0.74 1.2666 0.9851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M01 compound treatment 1.13524359E8 1.46E7 1.27 9.1564287E7 -3370000.0 -0.3 0.6861 0.5281 3011140 CMLD2_000549 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M02 compound treatment 9.5839956E7 -3040000.0 -0.26 1.02108539E8 7170000.0 0.63 0.2585 0.38 3131458 CMLD2_000550 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M03 compound treatment 1.10462142E8 1.16E7 1.0 9.4387931E7 -548000.0 -0.05 0.6738 0.6725 3131459 CMLD2_000551 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M04 compound treatment 1.01839705E8 2960000.0 0.26 9.9545471E7 4610000.0 0.4 0.4663 0.9759 3011143 CMLD2_000552 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M05 compound treatment 9.4917126E7 -3960000.0 -0.34 1.02740938E8 7810000.0 0.68 0.2413 0.3159 3011168 CMLD2_000553 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M06 compound treatment 8.0155188E7 -1.87E7 -1.62 8.999248E7 -4940000.0 -0.43 -1.4492 -0.8658 3131460 CMLD2_000554 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M07 compound treatment 1.01239116E8 2360000.0 0.2 1.02131385E8 7200000.0 0.63 0.5897 0.8907 3011171 CMLD2_000555 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M08 compound treatment 8.6004352E7 -1.29E7 -1.11 8.5945146E7 -8990000.0 -0.79 -1.3425 -0.9857 3131461 CMLD2_000556 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M09 mock treatment 9.5340712E7 -3530000.0 -0.31 9.3660198E7 -1280000.0 -0.11 -0.2948 -0.9069 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M10 mock treatment 9.5505044E7 -3370000.0 -0.29 9.3373645E7 -1560000.0 -0.14 -0.3025 -0.9406 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M11 compound treatment 7.7133805E7 -2.17E7 -1.88 7.2945551E7 -2.2E7 -1.92 -2.6887 -0.9999 3011173 CMLD2_000557 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M12 compound treatment 8.2493284E7 -1.64E7 -1.41 6.3186238E7 -3.17E7 -2.78 -2.9653 -0.951 3131462 CMLD2_000558 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(CC)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M13 mock treatment 9.3999144E7 -4880000.0 -0.42 9.5694993E7 759000.0 0.07 -0.2508 -0.5882 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M14 mock treatment 9.2281336E7 -6590000.0 -0.57 9.2626107E7 -2310000.0 -0.2 -0.5456 -0.9029 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M15 compound treatment 7.0732828E7 -2.81E7 -2.43 8.0194286E7 -1.47E7 -1.29 -2.631 -0.9561 3131463 CMLD2_000559 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M16 compound treatment 6.3046414E7 -3.58E7 -3.09 5.4139741E7 -4.08E7 -3.57 -4.7128 -0.9975 3011176 CMLD2_000560 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M17 compound treatment 9.6772488E7 -2100000.0 -0.18 9.5559277E7 624000.0 0.05 -0.0898 -0.4737 3131464 CMLD2_000561 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M18 compound treatment 9.1218799E7 -7660000.0 -0.66 8.8423166E7 -6510000.0 -0.57 -0.8706 -0.9973 3011178 CMLD2_000562 Cn1c(=O)n2CC[C@H]3[C@H]([C@H](O)[C@@H]4O[C@@H]4C3=O)n2c1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M19 compound treatment 1.03415279E8 4540000.0 0.39 9.9921542E7 4990000.0 0.44 0.5858 0.9986 3131465 CMLD2_000563 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M20 compound treatment 1.01021836E8 2150000.0 0.19 1.0000135E8 5070000.0 0.44 0.4446 0.9252 3011181 CMLD2_000564 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M21 compound treatment 7.7292959E7 -2.16E7 -1.86 8.3143765E7 -1.18E7 -1.03 -2.0479 -0.9611 3131466 CMLD2_000565 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M22 compound treatment 1.01148322E8 2270000.0 0.2 9.6794621E7 1860000.0 0.16 0.2539 0.9956 3011183 CMLD2_000566 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M23 compound treatment 9.2121725E7 -6750000.0 -0.58 1.03253533E8 8320000.0 0.73 0.1023 0.1096 3131467 CMLD2_000567 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 M24 compound treatment 9.7787968E7 -1090000.0 -0.09 9.6728863E7 1790000.0 0.16 0.0446 0.2437 3131468 CMLD2_000568 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N01 compound treatment 1.03422063E8 4550000.0 0.39 9.460712E7 -328000.0 -0.03 0.2574 0.6536 3131469 CMLD2_000569 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N02 compound treatment 9.7230232E7 -1650000.0 -0.14 9.7969813E7 3030000.0 0.27 0.0873 0.2899 3011201 CMLD2_000570 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N03 compound treatment 1.08466993E8 9590000.0 0.83 1.02972196E8 8040000.0 0.7 1.0832 0.9967 3131470 CMLD2_000571 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N04 compound treatment 9.9691526E7 816000.0 0.07 9.0843069E7 -4090000.0 -0.36 -0.2034 -0.5572 3131471 CMLD2_000572 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N05 compound treatment 8.2652143E7 -1.62E7 -1.4 1.0248606E8 7550000.0 0.66 -0.5236 -0.338 3011203 CMLD2_000573 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N06 compound treatment 8.0529428E7 -1.83E7 -1.58 9.6416666E7 1480000.0 0.13 -1.0288 -0.6471 3131472 CMLD2_000574 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N07 compound treatment 1.02988129E8 4110000.0 0.36 8.5914218E7 -9020000.0 -0.79 -0.3071 -0.3547 3011205 CMLD2_000575 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N08 compound treatment 8.8262033E7 -1.06E7 -0.92 9.4705756E7 -230000.0 -0.02 -0.6624 -0.7224 3131588 CMLD2_000576 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N09 mock treatment 9.9473285E7 598000.0 0.05 8.4706507E7 -1.02E7 -0.9 -0.5965 -0.6652 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N10 mock treatment 9.4183983E7 -4690000.0 -0.41 8.7697543E7 -7240000.0 -0.63 -0.7344 -0.9767 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N11 compound treatment 7.5993723E7 -2.29E7 -1.98 7.2571706E7 -2.24E7 -1.96 -2.7814 -1.0 3011207 CMLD2_000577 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N12 compound treatment 9.0519558E7 -8360000.0 -0.72 6.6953589E7 -2.8E7 -2.45 -2.242 -0.8782 3131589 CMLD2_000578 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N13 mock treatment 9.7595429E7 -1280000.0 -0.11 8.4709035E7 -1.02E7 -0.89 -0.711 -0.7885 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N14 mock treatment 8.2465518E7 -1.64E7 -1.42 8.1355676E7 -1.36E7 -1.19 -1.8426 -0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N15 compound treatment 7.2593668E7 -2.63E7 -2.27 9.5218362E7 283000.0 0.02 -1.5876 -0.6994 3131590 CMLD2_000579 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCCCC#C)n2c1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N16 compound treatment 3.154521E7 -6.73E7 -5.82 3.1954786E7 -6.3E7 -5.51 -8.0097 -0.9996 3011210 CMLD2_000580 C[C@@H](N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N17 compound treatment 9.9087523E7 212000.0 0.02 9.7338725E7 2400000.0 0.21 0.1617 0.7658 3131591 CMLD2_000581 C[C@H](N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N18 compound treatment 8.5327172E7 -1.35E7 -1.17 8.7233788E7 -7700000.0 -0.67 -1.3041 -0.9657 3011211 CMLD2_000582 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N19 compound treatment 1.01803396E8 2930000.0 0.25 8.9592761E7 -5340000.0 -0.47 -0.1518 -0.2856 3131592 CMLD2_000583 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N20 compound treatment 9.888888E7 13600.0 0.0 9.4771159E7 -164000.0 -0.01 -0.0093 -0.6472 3131593 CMLD2_000584 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N21 compound treatment 9.2244576E7 -6630000.0 -0.57 9.0266271E7 -4670000.0 -0.41 -0.6939 -0.9863 3011214 CMLD2_000585 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@H](C)C(=O)OC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N22 compound treatment 1.00061246E8 1190000.0 0.1 9.1918039E7 -3020000.0 -0.26 -0.1143 -0.4035 3011226 CMLD2_000586 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N23 compound treatment 1.10797702E8 1.19E7 1.03 1.04336359E8 9400000.0 0.82 1.3099 0.9938 3131594 CMLD2_000587 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]3CCCN3C(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 N24 compound treatment 1.03864081E8 4990000.0 0.43 1.04892912E8 9960000.0 0.87 0.9209 0.9473 3131054 CMLD2_000588 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O01 compound treatment 1.0077674E8 1900000.0 0.16 1.00727412E8 5790000.0 0.51 0.4746 0.8906 3131595 CMLD2_000589 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O02 compound treatment 1.00699187E8 1820000.0 0.16 9.4584408E7 -351000.0 -0.03 0.0897 0.5586 3011229 CMLD2_000590 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O03 compound treatment 8.4813711E7 -1.41E7 -1.21 9.8250429E7 3310000.0 0.29 -0.6537 -0.5235 3131596 CMLD2_000591 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O04 compound treatment 8.4303388E7 -1.46E7 -1.26 9.5476305E7 541000.0 0.05 -0.8565 -0.68 3011196 CMLD2_000592 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O05 compound treatment 1.03165023E8 4290000.0 0.37 1.00251706E8 5320000.0 0.47 0.591 0.9936 3131597 CMLD2_000593 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O06 compound treatment 9.9788546E7 913000.0 0.08 9.3399454E7 -1540000.0 -0.13 -0.0393 -0.252 3131598 CMLD2_000594 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O07 compound treatment 1.00088792E8 1210000.0 0.1 9.4950153E7 14600.0 0.0 0.075 0.7157 3011231 CMLD2_000595 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O08 compound treatment 9.466539E7 -4210000.0 -0.36 9.0619871E7 -4320000.0 -0.38 -0.5242 -0.9998 3131599 CMLD2_000596 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O09 compound treatment 9.4032915E7 -4840000.0 -0.42 9.324545E7 -1690000.0 -0.15 -0.4003 -0.9024 3011237 CMLD2_000597 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O10 compound treatment 9.479255E7 -4080000.0 -0.35 9.1184778E7 -3750000.0 -0.33 -0.4815 -0.9994 3131600 CMLD2_000598 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O11 mock treatment 9.662478E7 -2250000.0 -0.19 9.266084E7 -2270000.0 -0.2 -0.2782 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O12 mock treatment 9.1096904E7 -7780000.0 -0.67 8.6216433E7 -8720000.0 -0.76 -1.0146 -0.998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O13 compound treatment 7.2497133E7 -2.64E7 -2.28 8.2928569E7 -1.2E7 -1.05 -2.3541 -0.9383 3011239 CMLD2_000599 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O14 compound treatment 6.8818979E7 -3.01E7 -2.6 8.1013311E7 -1.39E7 -1.22 -2.6972 -0.9405 3131601 CMLD2_000600 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)/C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O15 compound treatment 8.843889E7 -1.04E7 -0.9 9.1067142E7 -3870000.0 -0.34 -0.8768 -0.9106 3131602 CMLD2_000601 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OC[C@@H](O)COCc5ccco5)n2c1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O16 compound treatment 4.9628559E7 -4.92E7 -4.25 5.500272E7 -3.99E7 -3.49 -5.4789 -0.9952 3012175 CMLD2_000602 CCOC(=O)CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O17 compound treatment 9.2418678E7 -6460000.0 -0.56 9.6911243E7 1980000.0 0.17 -0.2721 -0.466 3012176 CMLD2_000603 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O18 compound treatment 1.01327574E8 2450000.0 0.21 9.5472757E7 537000.0 0.05 0.183 0.8435 3012177 CMLD2_000604 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccccc4)C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O19 compound treatment 1.07970045E8 9090000.0 0.79 1.01986862E8 7050000.0 0.62 0.9918 0.9929 3012178 CMLD2_000605 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O20 compound treatment 9.816542E7 -710000.0 -0.06 9.8134992E7 3200000.0 0.28 0.1546 0.5395 3012179 CMLD2_000606 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O21 compound treatment 1.05698872E8 6820000.0 0.59 1.02194224E8 7260000.0 0.64 0.8659 0.9993 3131603 CMLD2_000607 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@@H](C)C(=O)OC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O22 compound treatment 1.07812766E8 8940000.0 0.77 9.9076604E7 4140000.0 0.36 0.8021 0.9406 3011105 CMLD2_000608 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O23 compound treatment 1.09912699E8 1.1E7 0.95 1.03093269E8 8160000.0 0.71 1.1789 0.9898 3012180 CMLD2_000609 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 O24 compound treatment 1.05946338E8 7070000.0 0.61 9.7048458E7 2110000.0 0.18 0.5626 0.8817 3131604 CMLD2_000610 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P01 compound treatment 1.08621383E8 9750000.0 0.84 1.01275086E8 6340000.0 0.55 0.9876 0.9795 3131605 CMLD2_000611 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P02 compound treatment 1.0342833E8 4550000.0 0.39 9.4536455E7 -399000.0 -0.03 0.2534 0.6418 3012181 CMLD2_000612 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P03 compound treatment 8.3612522E7 -1.53E7 -1.32 9.1950821E7 -2980000.0 -0.26 -1.1169 -0.8311 3131606 CMLD2_000613 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P04 compound treatment 7.5426698E7 -2.34E7 -2.03 9.3900521E7 -1040000.0 -0.09 -1.4962 -0.738 3012182 CMLD2_000614 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P05 compound treatment 1.03405747E8 4530000.0 0.39 9.6942697E7 2010000.0 0.18 0.4009 0.9347 3131723 CMLD2_000615 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P06 compound treatment 9.7829861E7 -1050000.0 -0.09 9.0492676E7 -4440000.0 -0.39 -0.3388 -0.8487 3131724 CMLD2_000616 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P07 compound treatment 1.01149507E8 2270000.0 0.2 9.5422435E7 487000.0 0.04 0.169 0.8409 3012183 CMLD2_000617 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P08 compound treatment 9.7109294E7 -1770000.0 -0.15 9.1723056E7 -3210000.0 -0.28 -0.3067 -0.9587 3131725 CMLD2_000618 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P09 compound treatment 9.4286865E7 -4590000.0 -0.4 9.6556522E7 1620000.0 0.14 -0.1799 -0.4274 3012184 CMLD2_000619 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P10 compound treatment 9.8511212E7 -364000.0 -0.03 8.4993548E7 -9940000.0 -0.87 -0.6375 -0.7322 3131726 CMLD2_000620 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P11 mock treatment 9.5441574E7 -3430000.0 -0.3 9.1006457E7 -3930000.0 -0.34 -0.4529 -0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P12 mock treatment 9.3096747E7 -5780000.0 -0.5 8.5194092E7 -9740000.0 -0.85 -0.9558 -0.9675 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P13 compound treatment 7.0379463E7 -2.85E7 -2.46 8.0804178E7 -1.41E7 -1.24 -2.6149 -0.9493 3131727 CMLD2_000621 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P14 compound treatment 7.2950774E7 -2.59E7 -2.24 8.4431962E7 -1.05E7 -0.92 -2.2333 -0.9227 3012185 CMLD2_000622 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P15 compound treatment 9.5782669E7 -3090000.0 -0.27 8.837013E7 -6570000.0 -0.57 -0.5952 -0.9393 3131728 CMLD2_000623 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P16 compound treatment 3.2985164E7 -6.59E7 -5.69 3.7297246E7 -5.76E7 -5.04 -7.5911 -0.9982 3012186 CMLD2_000624 CC(C)(C)N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P17 compound treatment 1.02046373E8 3170000.0 0.27 9.6576535E7 1640000.0 0.14 0.2952 0.9546 3131729 CMLD2_000625 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P18 compound treatment 9.7326491E7 -1550000.0 -0.13 9.4230082E7 -705000.0 -0.06 -0.1382 -0.9383 3012187 CMLD2_000626 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P19 compound treatment 1.04753165E8 5880000.0 0.51 9.8898873E7 3960000.0 0.35 0.6043 0.9827 3131730 CMLD2_000627 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P20 compound treatment 1.01780808E8 2910000.0 0.25 9.7310355E7 2370000.0 0.21 0.3244 0.9956 3012188 CMLD2_000628 C[C@H]/1COC(=O)C\C=C\[C@@H](C)[C@H]2O[C@H](COC(=O)C\C=C1)[C@@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P21 compound treatment 1.06006908E8 7130000.0 0.62 1.02273337E8 7340000.0 0.64 0.8897 0.9998 3131731 CMLD2_000629 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P22 compound treatment 1.05313525E8 6440000.0 0.56 1.00616857E8 5680000.0 0.5 0.7448 0.9984 3012189 CMLD2_000630 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)COC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P23 compound treatment 1.11892922E8 1.3E7 1.12 1.08011937E8 1.31E7 1.14 1.6043 1.0 3131732 CMLD2_000631 CO[C@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](OCc3ccccc3)/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2110 P24 compound treatment 1.10100116E8 1.12E7 0.97 1.02176002E8 7240000.0 0.63 1.1336 0.9788 3131733 CMLD2_000632 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A01 compound treatment 1.14364751E8 1.29E7 1.12 1.0384569E8 6570000.0 0.58 1.1963 0.9524 3012190 CMLD2_000633 CO[C@@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A02 compound treatment 1.10992453E8 9560000.0 0.83 9.4968723E7 -2300000.0 -0.2 0.4409 0.519 3131321 CMLD2_000634 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A03 compound treatment 1.09546664E8 8110000.0 0.7 1.01714093E8 4440000.0 0.39 0.7701 0.9614 3131734 CMLD2_000635 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A04 compound treatment 9.6861176E7 -4580000.0 -0.4 9.8706205E7 1430000.0 0.13 -0.1908 -0.4602 3131735 CMLD2_000636 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A05 compound treatment 1.11353585E8 9920000.0 0.86 1.02427647E8 5150000.0 0.45 0.9246 0.9551 3012191 CMLD2_000637 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A06 compound treatment 1.07907939E8 6470000.0 0.56 9.1141772E7 -6130000.0 -0.54 0.0157 0.0203 3131736 CMLD2_000638 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A07 compound treatment 1.01149651E8 -287000.0 -0.02 1.03732998E8 6460000.0 0.57 0.3822 0.6754 3012192 CMLD2_000639 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A08 compound treatment 9.8378371E7 -3060000.0 -0.26 1.03331197E8 6060000.0 0.53 0.1881 0.3175 3131737 CMLD2_000640 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A09 compound treatment 1.08481843E8 7040000.0 0.61 1.05708685E8 8430000.0 0.74 0.9522 0.9954 3131738 CMLD2_000641 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)cc2)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A10 compound treatment 1.07498249E8 6060000.0 0.52 9.0984429E7 -6290000.0 -0.55 -0.019 -0.025 3012193 CMLD2_000642 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A11 compound treatment 9.9215613E7 -2220000.0 -0.19 9.9513286E7 2240000.0 0.2 0.0029 0.0106 3131739 CMLD2_000643 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A12 compound treatment 9.2431102E7 -9010000.0 -0.78 9.9448684E7 2170000.0 0.19 -0.4154 -0.5188 3012194 CMLD2_000644 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A13 mock treatment 1.02459913E8 1020000.0 0.09 9.7923441E7 650000.0 0.06 0.1027 0.9773 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A14 mock treatment 9.7719257E7 -3720000.0 -0.32 9.0517307E7 -6760000.0 -0.59 -0.6452 -0.9588 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A15 compound treatment 1.02996886E8 1560000.0 0.13 9.9286904E7 2010000.0 0.18 0.2198 0.9912 3131740 CMLD2_000645 CCc1cc2CN(CC/C(=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A16 compound treatment 1.0154101E8 104000.0 0.01 9.9819524E7 2550000.0 0.22 0.1639 0.735 3131741 CMLD2_000646 CCc1cc2CN(CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A17 compound treatment 1.0583547E8 4400000.0 0.38 1.01864448E8 4590000.0 0.4 0.5527 0.9996 3012195 CMLD2_000647 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cc(no5)c6c(C)cc(C)cc6C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A18 compound treatment 9.3802683E7 -7630000.0 -0.66 9.4214457E7 -3060000.0 -0.27 -0.6556 -0.9212 3131860 CMLD2_000648 CO[C@H](/C=N/O[C@@H](C)c1cc(no1)c2c(C)cc(C)cc2C)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A19 compound treatment 1.06280125E8 4840000.0 0.42 1.0336065E8 6090000.0 0.53 0.6725 0.9928 3012196 CMLD2_000649 C[C@H](ON=C(C)C)c1cc(no1)c2c(C)cc(C)cc2C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A20 compound treatment 1.05389447E8 3950000.0 0.34 1.02227799E8 4950000.0 0.43 0.548 0.993 3131861 CMLD2_000650 CO/N=C/[C@@H](C)[C@H](OCc1ccccc1)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A21 compound treatment 1.07869406E8 6430000.0 0.56 1.04938568E8 7660000.0 0.67 0.8672 0.9956 3131714 CMLD2_000651 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A22 compound treatment 9.8809923E7 -2630000.0 -0.23 9.4298792E7 -2970000.0 -0.26 -0.3446 -0.9977 3012197 CMLD2_000652 C[C@@H]1CC[C@@H]2N(C[C@@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A23 mock treatment 1.07550974E8 6110000.0 0.53 1.08595425E8 1.13E7 0.99 1.074 0.9566 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 A24 mock treatment 1.11004487E8 9570000.0 0.83 1.05324426E8 8050000.0 0.7 1.0825 0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B01 compound treatment 1.12928514E8 1.15E7 0.99 1.07035883E8 9760000.0 0.85 1.306 0.9972 3131862 CMLD2_000653 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B02 compound treatment 1.07881195E8 6440000.0 0.56 8.7529414E7 -9740000.0 -0.85 -0.2094 -0.2057 3011062 CMLD2_000654 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B03 compound treatment 9.7573802E7 -3860000.0 -0.33 9.8668121E7 1390000.0 0.12 -0.1497 -0.4212 3131863 CMLD2_000655 CO[C@@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B04 compound treatment 1.0296057E8 1520000.0 0.13 9.8176719E7 903000.0 0.08 0.1489 0.9702 3012198 CMLD2_000656 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B05 compound treatment 1.0546314E8 4030000.0 0.35 9.7846375E7 573000.0 0.05 0.2813 0.8007 3131864 CMLD2_000657 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cc(no4)c5c(C)cc(C)cc5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B06 compound treatment 1.04462652E8 3030000.0 0.26 8.5841496E7 -1.14E7 -1.0 -0.5227 -0.5055 3131865 CMLD2_000658 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cc(no2)c3c(C)cc(C)cc3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B07 compound treatment 9.7500463E7 -3940000.0 -0.34 1.02423916E8 5150000.0 0.45 0.0783 0.1387 3012199 CMLD2_000659 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B08 compound treatment 1.02292158E8 855000.0 0.07 1.01395019E8 4120000.0 0.36 0.3073 0.8346 3131866 CMLD2_000660 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B09 compound treatment 1.03209075E8 1770000.0 0.15 1.04146822E8 6870000.0 0.6 0.5336 0.8596 3131867 CMLD2_000661 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B10 compound treatment 1.03020003E8 1580000.0 0.14 8.6627109E7 -1.06E7 -0.93 -0.5622 -0.597 3012228 CMLD2_000662 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B11 compound treatment 9.6689469E7 -4750000.0 -0.41 9.9345727E7 2070000.0 0.18 -0.1617 -0.3607 3131868 CMLD2_000663 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B12 compound treatment 9.726243E7 -4170000.0 -0.36 9.0141914E7 -7130000.0 -0.62 -0.6963 -0.966 3130911 CMLD2_000664 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B13 mock treatment 1.03173282E8 1740000.0 0.15 1.01099895E8 3830000.0 0.33 0.3428 0.9344 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B14 mock treatment 1.0124703E8 -190000.0 -0.02 9.4948333E7 -2330000.0 -0.2 -0.1555 -0.7617 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B15 compound treatment 8.7853869E7 -1.36E7 -1.17 8.7171282E7 -1.01E7 -0.88 -1.4548 -0.9903 3131869 CMLD2_000665 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(CC)c(CC)cc3C2)C=C[C@@H]1Oc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B16 compound treatment 1.00176771E8 -1260000.0 -0.11 9.2436136E7 -4840000.0 -0.42 -0.3763 -0.8609 3012230 CMLD2_000666 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B17 compound treatment 1.06455226E8 5020000.0 0.43 1.00471345E8 3200000.0 0.28 0.5044 0.9776 3131870 CMLD2_000667 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B18 compound treatment 1.04206703E8 2770000.0 0.24 1.01077378E8 3800000.0 0.33 0.4045 0.9869 3012231 CMLD2_000668 CO[C@H](/C=N/OC[C@@H](C)[C@H](OCc1ccccc1)C(C)C)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B19 compound treatment 9.7257193E7 -4180000.0 -0.36 9.2161738E7 -5110000.0 -0.45 -0.5716 -0.9943 3131871 CMLD2_000669 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CON=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B20 compound treatment 9.9009997E7 -2430000.0 -0.21 1.00193405E8 2920000.0 0.26 0.0324 0.0982 3012232 CMLD2_000670 CCc1cc2CN(CC/C(=N/OC)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B21 compound treatment 9.7652266E7 -3780000.0 -0.33 8.9044152E7 -8230000.0 -0.72 -0.7404 -0.9361 3131872 CMLD2_000671 C[C@@H]1CC[C@@H]2N(C[C@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B22 compound treatment 1.06769468E8 5330000.0 0.46 1.02502377E8 5230000.0 0.46 0.6492 1.0 3131873 CMLD2_000672 COc1ccc(OC[C@H]2CN3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B23 mock treatment 1.04241167E8 2800000.0 0.24 1.00051327E8 2780000.0 0.24 0.3431 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 B24 mock treatment 1.06447772E8 5010000.0 0.43 1.03843869E8 6570000.0 0.58 0.7126 0.9902 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C01 compound treatment 1.08464102E8 7030000.0 0.61 1.06642156E8 9370000.0 0.82 1.0089 0.989 3012233 CMLD2_000673 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C02 compound treatment 1.04841011E8 3400000.0 0.29 1.02680221E8 5410000.0 0.47 0.5425 0.9738 3011181 CMLD2_000674 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C03 compound treatment 9.7401208E7 -4040000.0 -0.35 9.2917817E7 -4360000.0 -0.38 -0.5161 -0.999 3131874 CMLD2_000675 CO[C@@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C04 compound treatment 1.07522543E8 6090000.0 0.53 1.01324481E8 4050000.0 0.35 0.6223 0.9816 3131875 CMLD2_000676 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C05 compound treatment 1.06424401E8 4990000.0 0.43 9.6515153E7 -759000.0 -0.07 0.2577 0.5912 3012234 CMLD2_000677 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C06 compound treatment 9.4600378E7 -6840000.0 -0.59 9.6375649E7 -898000.0 -0.08 -0.4731 -0.7942 3131876 CMLD2_000678 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C07 compound treatment 1.00995534E8 -442000.0 -0.04 8.7010897E7 -1.03E7 -0.9 -0.6621 -0.7365 3131877 CMLD2_000679 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C08 compound treatment 1.03000309E8 1560000.0 0.14 9.4143205E7 -3130000.0 -0.27 -0.0983 -0.3217 3012270 CMLD2_000680 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)cc2)c6ccc(C)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C09 compound treatment 1.00216144E8 -1220000.0 -0.11 9.7013732E7 -260000.0 -0.02 -0.0907 -0.8403 3131878 CMLD2_000681 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C10 compound treatment 8.9594175E7 -1.18E7 -1.02 9.2136082E7 -5140000.0 -0.45 -1.0412 -0.9319 3131879 CMLD2_000682 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C11 mock treatment 9.9893267E7 -1540000.0 -0.13 8.8183713E7 -9090000.0 -0.8 -0.6568 -0.8143 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C12 mock treatment 9.9241618E7 -2200000.0 -0.19 9.3399839E7 -3870000.0 -0.34 -0.3738 -0.9623 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C13 compound treatment 9.8186813E7 -3250000.0 -0.28 9.6900611E7 -373000.0 -0.03 -0.2216 -0.7841 3012273 CMLD2_000683 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C14 compound treatment 9.1644126E7 -9790000.0 -0.85 9.3844432E7 -3430000.0 -0.3 -0.8103 -0.9029 3131994 CMLD2_000684 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C15 mock treatment 1.015693E8 132000.0 0.01 8.5921966E7 -1.14E7 -0.99 -0.6944 -0.6989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C16 mock treatment 1.00933219E8 -504000.0 -0.04 9.6166813E7 -1110000.0 -0.1 -0.0993 -0.9348 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C17 compound treatment 9.845291E7 -2980000.0 -0.26 8.9664279E7 -7610000.0 -0.67 -0.6532 -0.9147 3131995 CMLD2_000685 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C18 compound treatment 9.6711503E7 -4730000.0 -0.41 9.8623395E7 1350000.0 0.12 -0.2051 -0.4827 3012274 CMLD2_000686 CO[C@H](/C=N/O[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C19 compound treatment 1.05738405E8 4300000.0 0.37 9.2323001E7 -4950000.0 -0.43 -0.0437 -0.0765 3012275 CMLD2_000687 CC(=NO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C20 compound treatment 1.003897E8 -1050000.0 -0.09 9.4802787E7 -2470000.0 -0.22 -0.2169 -0.9252 3131996 CMLD2_000688 CO/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C21 compound treatment 1.08137928E8 6700000.0 0.58 1.03282661E8 6010000.0 0.53 0.7811 0.9989 3011349 CMLD2_000689 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C22 compound treatment 1.00851983E8 -585000.0 -0.05 1.03730311E8 6460000.0 0.57 0.3638 0.6413 3131997 CMLD2_000690 COc1ccc(OC[C@@H]2CC3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C23 mock treatment 1.10928218E8 9490000.0 0.82 9.4454532E7 -2820000.0 -0.25 0.4052 0.4733 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 C24 mock treatment 1.13280176E8 1.18E7 1.02 1.07996382E8 1.07E7 0.94 1.3869 0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D01 compound treatment 1.06970392E8 5530000.0 0.48 1.07081344E8 9810000.0 0.86 0.9449 0.9618 3012277 CMLD2_000691 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D02 compound treatment 1.07288075E8 5850000.0 0.51 9.0546102E7 -6730000.0 -0.59 -0.059 -0.076 3131998 CMLD2_000692 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](CCSC)NC(=O)C\C=C\[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D03 compound treatment 9.5336096E7 -6100000.0 -0.53 1.01516694E8 4240000.0 0.37 -0.11 -0.1707 3012278 CMLD2_000693 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)CCC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D04 compound treatment 1.03475054E8 2040000.0 0.18 9.9143045E7 1870000.0 0.16 0.2402 0.9993 3131999 CMLD2_000694 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D05 compound treatment 1.04925673E8 3490000.0 0.3 9.9718109E7 2440000.0 0.21 0.3643 0.9859 3132000 CMLD2_000695 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D06 compound treatment 9.8855399E7 -2580000.0 -0.22 8.4971537E7 -1.23E7 -1.08 -0.919 -0.8358 3012279 CMLD2_000696 CC(=O)OC[C@H]1O[C@H](C/C=N/OC2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D07 compound treatment 9.5467775E7 -5970000.0 -0.52 9.8469555E7 1200000.0 0.1 -0.2906 -0.5523 3132001 CMLD2_000697 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1Oc4ccc(OC)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D08 compound treatment 9.5048514E7 -6390000.0 -0.55 9.248795E7 -4790000.0 -0.42 -0.6863 -0.9907 3132002 CMLD2_000698 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/c2ccc(cc2)C(=O)N3[C@@H](CC[C@H](C)[C@H]3c4ccc(C)cc4)C(=O)OC)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D09 compound treatment 1.01408049E8 -29000.0 0.0 9.8850672E7 1580000.0 0.14 0.0958 0.6941 3012280 CMLD2_000699 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D10 compound treatment 1.00852077E8 -585000.0 -0.05 8.4763352E7 -1.25E7 -1.09 -0.8099 -0.739 3132003 CMLD2_000700 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D11 mock treatment 9.2972838E7 -8460000.0 -0.73 9.7250598E7 -23100.0 0.0 -0.5184 -0.7091 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D12 mock treatment 9.625852E7 -5180000.0 -0.45 8.8251092E7 -9020000.0 -0.79 -0.8746 -0.9638 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D13 compound treatment 1.04074011E8 2640000.0 0.23 9.7240643E7 -33100.0 0.0 0.159 0.6981 3012281 CMLD2_000701 CC1(C)O[C@H]2O[C@H]([C@H](O)CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)[C@H](O)[C@H]2O1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D14 compound treatment 1.11495846E8 1.01E7 0.87 9.8242234E7 969000.0 0.08 0.6743 0.7724 3132004 CMLD2_000702 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D15 mock treatment 9.4749886E7 -6690000.0 -0.58 9.9562712E7 2290000.0 0.2 -0.2668 -0.4364 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D16 mock treatment 1.00506947E8 -930000.0 -0.08 9.6223581E7 -1050000.0 -0.09 -0.1218 -0.9978 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D17 compound treatment 1.03739985E8 2300000.0 0.2 1.02661404E8 5390000.0 0.47 0.4741 0.9263 3132005 CMLD2_000703 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D18 compound treatment 1.04709445E8 3270000.0 0.28 9.0130882E7 -7140000.0 -0.63 -0.2422 -0.353 3012283 CMLD2_000704 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D19 compound treatment 9.7393731E7 -4040000.0 -0.35 9.9487428E7 2210000.0 0.19 -0.11 -0.2753 3132006 CMLD2_000705 C[C@@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D20 compound treatment 1.04369172E8 2930000.0 0.25 9.9110382E7 1840000.0 0.16 0.2927 0.9759 3012284 CMLD2_000706 CO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D21 compound treatment 1.12149227E8 1.07E7 0.93 1.03709776E8 6440000.0 0.56 1.0525 0.9717 3132007 CMLD2_000707 CCCC[C@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D22 compound treatment 1.10544698E8 9110000.0 0.79 9.5102435E7 -2170000.0 -0.19 0.4219 0.5213 3132008 CMLD2_000708 C[C@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D23 mock treatment 1.02811153E8 1370000.0 0.12 1.06466896E8 9190000.0 0.8 0.6528 0.8027 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 D24 mock treatment 1.10741583E8 9300000.0 0.8 1.06187509E8 8910000.0 0.78 1.1199 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E01 mock treatment 1.10115018E8 8680000.0 0.75 1.01643932E8 4370000.0 0.38 0.8004 0.9512 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E02 mock treatment 1.08051259E8 6610000.0 0.57 9.9438673E7 2160000.0 0.19 0.5379 0.8938 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E03 compound treatment 1.05241361E8 3800000.0 0.33 9.9443603E7 2170000.0 0.19 0.3666 0.966 3012286 CMLD2_000709 CO[C@@H]1COC(=O)CCC[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E04 compound treatment 1.01250988E8 -186000.0 -0.02 9.4721134E7 -2550000.0 -0.22 -0.1693 -0.756 3132009 CMLD2_000710 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E05 compound treatment 1.01195401E8 -242000.0 -0.02 9.7441507E7 168000.0 0.01 -0.0044 -0.1715 3012287 CMLD2_000711 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E06 compound treatment 9.8324271E7 -3110000.0 -0.27 9.4269858E7 -3000000.0 -0.26 -0.376 -0.9999 3132010 CMLD2_000712 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E07 compound treatment 9.9457692E7 -1980000.0 -0.17 9.7577272E7 304000.0 0.03 -0.1021 -0.5901 3012333 CMLD2_000713 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E08 compound treatment 9.5147035E7 -6290000.0 -0.54 9.1181088E7 -6090000.0 -0.53 -0.7612 -1.0 3132011 CMLD2_000714 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)cc2)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E09 mock treatment 9.5216061E7 -6220000.0 -0.54 9.4870037E7 -2400000.0 -0.21 -0.5287 -0.9162 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E10 mock treatment 9.1362016E7 -1.01E7 -0.87 8.7881831E7 -9390000.0 -0.82 -1.1965 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E11 compound treatment 1.01093479E8 -344000.0 -0.03 9.78017E7 528000.0 0.05 0.0117 0.2128 3012334 CMLD2_000715 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E12 compound treatment 9.1781988E7 -9660000.0 -0.83 9.1978E7 -5300000.0 -0.46 -0.9174 -0.9616 3132012 CMLD2_000716 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E13 compound treatment 9.6050572E7 -5390000.0 -0.47 9.2144723E7 -5130000.0 -0.45 -0.6464 -0.9998 3012337 CMLD2_000717 OC[C@H]1O[C@H](CC=C)C=C[C@@H]1O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E14 compound treatment 9.5885766E7 -5550000.0 -0.48 9.3591188E7 -3680000.0 -0.32 -0.5669 -0.9813 3132130 CMLD2_000718 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E15 compound treatment 9.9125327E7 -2310000.0 -0.2 9.7568702E7 295000.0 0.03 -0.1229 -0.6106 3132131 CMLD2_000719 CCc1cc2CN(CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E16 compound treatment 9.9044628E7 -2390000.0 -0.21 9.7060767E7 -213000.0 -0.02 -0.1593 -0.7678 3132132 CMLD2_000720 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6)c7ccccc7)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E17 mock treatment 1.06581328E8 5140000.0 0.44 9.9547843E7 2270000.0 0.2 0.4549 0.9344 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E18 mock treatment 1.04828081E8 3390000.0 0.29 1.00550819E8 3280000.0 0.29 0.4099 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E19 compound treatment 1.02252114E8 815000.0 0.07 1.01140127E8 3870000.0 0.34 0.289 0.8363 3012338 CMLD2_000721 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E20 mock treatment 9.9928636E7 -1510000.0 -0.13 1.00159178E8 2890000.0 0.25 0.0864 0.3042 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E21 compound treatment 1.07921741E8 6480000.0 0.56 1.01168294E8 3890000.0 0.34 0.6371 0.9716 3131584 CMLD2_000722 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E22 compound treatment 1.0436867E8 2930000.0 0.25 1.01659081E8 4390000.0 0.38 0.4504 0.9796 3012339 CMLD2_000723 COC(=O)C/C=C/[C@@H](C)[C@H](OCc1cccc(c1)c2ccccc2)C3CCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E23 mock treatment 1.08867948E8 7430000.0 0.64 1.01267181E8 3990000.0 0.35 0.701 0.9592 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 E24 mock treatment 1.09616224E8 8180000.0 0.71 1.03727993E8 6450000.0 0.56 0.899 0.9939 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F01 mock treatment 1.08674158E8 7240000.0 0.63 1.02358526E8 5080000.0 0.45 0.7567 0.9861 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F02 mock treatment 1.0672793E8 5290000.0 0.46 9.5647828E7 -1630000.0 -0.14 0.2225 0.4649 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F03 compound treatment 1.05206349E8 3770000.0 0.33 1.00309754E8 3040000.0 0.27 0.4181 0.9949 3132133 CMLD2_000724 C[C@H]1/C=C/CC(=O)OC[C@H](NS(=O)(=O)c2ccc(C)cc2)[C@@H](C)/C=C/CC(=O)OC[C@@H]1NS(=O)(=O)c3ccc(C)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F04 compound treatment 1.00277828E8 -1160000.0 -0.1 9.6548364E7 -725000.0 -0.06 -0.1157 -0.9758 3012198 CMLD2_000725 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F05 compound treatment 9.8907529E7 -2530000.0 -0.22 9.832791E7 1050000.0 0.09 -0.0893 -0.3763 3132134 CMLD2_000726 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F06 compound treatment 1.00341063E8 -1100000.0 -0.09 9.3660734E7 -3610000.0 -0.32 -0.2905 -0.8802 3012341 CMLD2_000727 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F07 compound treatment 9.5408788E7 -6030000.0 -0.52 9.96537E7 2380000.0 0.21 -0.2209 -0.3939 3132135 CMLD2_000728 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F08 compound treatment 9.3968416E7 -7470000.0 -0.65 9.2937918E7 -4340000.0 -0.38 -0.7245 -0.968 3132136 CMLD2_000729 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)cc2)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F09 mock treatment 9.6141887E7 -5300000.0 -0.46 9.6676203E7 -597000.0 -0.05 -0.3604 -0.7829 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F10 mock treatment 9.4509212E7 -6930000.0 -0.6 9.097915E7 -6290000.0 -0.55 -0.8127 -0.9991 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F11 compound treatment 9.9620528E7 -1820000.0 -0.16 9.8220376E7 947000.0 0.08 -0.0524 -0.2951 3012342 CMLD2_000730 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F12 compound treatment 9.3328989E7 -8110000.0 -0.7 9.128724E7 -5990000.0 -0.52 -0.8657 -0.9898 3132137 CMLD2_000731 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F13 compound treatment 9.7271036E7 -4170000.0 -0.36 9.4059451E7 -3210000.0 -0.28 -0.4534 -0.9926 3010880 CMLD2_000732 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F14 compound treatment 9.541227E7 -6020000.0 -0.52 9.3742898E7 -3530000.0 -0.31 -0.5865 -0.969 3012343 CMLD2_000733 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F15 compound treatment 9.964474E7 -1790000.0 -0.15 9.9650064E7 2380000.0 0.21 0.0376 0.145 3132138 CMLD2_000734 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F16 compound treatment 9.4499119E7 -6940000.0 -0.6 9.5548436E7 -1730000.0 -0.15 -0.5305 -0.8584 3132139 CMLD2_000735 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1Oc6ccc(OC)cc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F17 mock treatment 1.03593559E8 2160000.0 0.19 1.03063401E8 5790000.0 0.51 0.49 0.9077 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F18 mock treatment 1.00713668E8 -723000.0 -0.06 9.9703192E7 2430000.0 0.21 0.1062 0.479 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F19 compound treatment 9.77875E7 -3650000.0 -0.32 9.0505081E7 -6770000.0 -0.59 -0.6418 -0.9564 3012344 CMLD2_000736 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F20 mock treatment 1.000065E8 -1430000.0 -0.12 9.8007517E7 734000.0 0.06 -0.042 -0.3013 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F21 compound treatment 1.09490972E8 8050000.0 0.7 1.02847778E8 5570000.0 0.49 0.8368 0.9849 3012345 CMLD2_000737 C[C@@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F22 compound treatment 1.02479662E8 1040000.0 0.09 9.9914956E7 2640000.0 0.23 0.2271 0.9155 3132140 CMLD2_000738 CO[C@@H]([C@H](C)/C=C/CC(=O)OCCCc1ccccc1)C2CCCCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F23 mock treatment 1.10444131E8 9010000.0 0.78 1.05351324E8 8080000.0 0.71 1.05 0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 F24 mock treatment 1.08363246E8 6930000.0 0.6 1.03068192E8 5790000.0 0.51 0.7816 0.9966 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G01 compound treatment 1.06116044E8 4680000.0 0.4 1.02719551E8 5450000.0 0.48 0.6228 0.9966 3132141 CMLD2_000739 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G02 compound treatment 1.12103783E8 1.07E7 0.92 9.4310356E7 -2960000.0 -0.26 0.4681 0.4891 3012346 CMLD2_000740 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G03 mock treatment 1.06542021E8 5100000.0 0.44 9.887268E7 1600000.0 0.14 0.4107 0.8879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G04 mock treatment 1.02806049E8 1370000.0 0.12 9.2064306E7 -5210000.0 -0.46 -0.2388 -0.5069 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G05 compound treatment 9.8975162E7 -2460000.0 -0.21 9.3455868E7 -3820000.0 -0.33 -0.3866 -0.9762 3132142 CMLD2_000741 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G06 compound treatment 9.594324E7 -5490000.0 -0.47 9.3943959E7 -3330000.0 -0.29 -0.5416 -0.9726 3012347 CMLD2_000742 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G07 mock treatment 1.01486108E8 49000.0 0.0 9.6618363E7 -655000.0 -0.06 -0.0376 -0.6531 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G08 mock treatment 9.2508718E7 -8930000.0 -0.77 9.1534861E7 -5740000.0 -0.5 -0.9004 -0.9784 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G09 compound treatment 9.6401136E7 -5040000.0 -0.43 9.2510553E7 -4760000.0 -0.42 -0.6023 -0.9998 3132143 CMLD2_000743 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G10 compound treatment 9.5054033E7 -6380000.0 -0.55 8.918958E7 -8080000.0 -0.71 -0.8901 -0.9924 3132144 CMLD2_000744 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C\3/[C@H](O)[C@H](Oc4ccc(OC)cc34)c5cccc(OC)c5)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G11 compound treatment 9.6380255E7 -5060000.0 -0.44 9.0526343E7 -6750000.0 -0.59 -0.7264 -0.989 3132145 CMLD2_000745 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G12 compound treatment 9.6779974E7 -4660000.0 -0.4 9.0727469E7 -6550000.0 -0.57 -0.6895 -0.985 3012401 CMLD2_000746 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G13 compound treatment 9.3287741E7 -8150000.0 -0.7 9.3369911E7 -3900000.0 -0.34 -0.7393 -0.9449 3132146 CMLD2_000747 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@@H]7COC[C@H]7O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G14 compound treatment 9.3308743E7 -8130000.0 -0.7 9.1310886E7 -5960000.0 -0.52 -0.8654 -0.9893 3012403 CMLD2_000748 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G15 compound treatment 9.1824509E7 -9610000.0 -0.83 9.31016E7 -4170000.0 -0.37 -0.8453 -0.9319 3132147 CMLD2_000749 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G16 compound treatment 9.2068621E7 -9370000.0 -0.81 9.181896E7 -5450000.0 -0.48 -0.9097 -0.9683 3012404 CMLD2_000750 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G17 compound treatment 1.03424479E8 1990000.0 0.17 9.6579179E7 -695000.0 -0.06 0.0784 0.4305 3132148 CMLD2_000751 CO[C@H](/C=N/OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G18 compound treatment 9.9459876E7 -1980000.0 -0.17 9.5137818E7 -2140000.0 -0.19 -0.2529 -0.999 3132267 CMLD2_000752 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CON=C(C)C)c3ccccc3)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G19 mock treatment 1.02914163E8 1480000.0 0.13 9.8054882E7 781000.0 0.07 0.1386 0.9572 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G20 mock treatment 1.02942651E8 1510000.0 0.13 1.00188448E8 2910000.0 0.26 0.2723 0.9511 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G21 compound treatment 1.07810993E8 6370000.0 0.55 9.720172E7 -72000.0 -0.01 0.3848 0.699 3012405 CMLD2_000753 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G22 compound treatment 9.559806E7 -5840000.0 -0.5 8.8740669E7 -8530000.0 -0.75 -0.8847 -0.9817 3132268 CMLD2_000754 CO[C@H]([C@@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)CO)C2CCCCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G23 mock treatment 1.09350664E8 7910000.0 0.68 1.00011558E8 2740000.0 0.24 0.6527 0.9012 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 G24 mock treatment 1.02608227E8 1170000.0 0.1 1.04128723E8 6860000.0 0.6 0.4957 0.8148 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H01 compound treatment 1.09638339E8 8200000.0 0.71 1.0239828E8 5120000.0 0.45 0.818 0.9757 3012408 CMLD2_000755 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H02 compound treatment 1.04509989E8 3070000.0 0.27 9.4104881E7 -3170000.0 -0.28 -0.0084 -0.0219 3132269 CMLD2_000756 C[C@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H03 mock treatment 1.05562398E8 4130000.0 0.36 1.00505624E8 3230000.0 0.28 0.452 0.9935 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H04 mock treatment 9.7230998E7 -4210000.0 -0.36 8.9508078E7 -7770000.0 -0.68 -0.7375 -0.9569 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H05 compound treatment 1.02952415E8 1520000.0 0.13 9.5926152E7 -1350000.0 -0.12 0.0092 0.052 3132270 CMLD2_000757 CC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H06 compound treatment 9.1701771E7 -9740000.0 -0.84 9.0250268E7 -7020000.0 -0.61 -1.0292 -0.9881 3012411 CMLD2_000758 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCCCc4nc(C)c(C)cc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H07 mock treatment 1.00914692E8 -522000.0 -0.05 9.8580394E7 1310000.0 0.11 0.049 0.3982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H08 compound treatment 9.2641026E7 -8800000.0 -0.76 8.8919353E7 -8350000.0 -0.73 -1.0542 -0.9998 3132271 CMLD2_000759 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)cc2)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H09 compound treatment 9.0233902E7 -1.12E7 -0.97 9.6862047E7 -412000.0 -0.04 -0.7097 -0.7329 3132272 CMLD2_000760 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H10 compound treatment 9.3558435E7 -7880000.0 -0.68 9.2098745E7 -5170000.0 -0.45 -0.8014 -0.9804 3012412 CMLD2_000761 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C\2/[C@H](O)[C@H](Oc3ccc(OC)cc23)c4cccc(OC)c4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H11 compound treatment 9.799846E7 -3440000.0 -0.3 9.5362409E7 -1910000.0 -0.17 -0.3283 -0.9631 3132273 CMLD2_000762 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H12 compound treatment 9.5601524E7 -5840000.0 -0.5 8.7531758E7 -9740000.0 -0.85 -0.9593 -0.9685 3132274 CMLD2_000763 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H13 compound treatment 9.6236535E7 -5200000.0 -0.45 9.4499384E7 -2770000.0 -0.24 -0.4893 -0.9583 3012414 CMLD2_000764 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H14 compound treatment 9.2350604E7 -9090000.0 -0.78 9.1513316E7 -5760000.0 -0.5 -0.9114 -0.9771 3132275 CMLD2_000765 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)COCc2ccco2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H15 compound treatment 9.5418718E7 -6020000.0 -0.52 9.9272404E7 2000000.0 0.17 -0.2439 -0.4447 3012415 CMLD2_000766 CCc1cc2CN(CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H16 compound treatment 9.4000463E7 -7440000.0 -0.64 8.7261969E7 -1.0E7 -0.88 -1.0738 -0.9883 3132276 CMLD2_000767 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H17 compound treatment 1.04411693E8 2970000.0 0.26 9.9920463E7 2650000.0 0.23 0.3455 0.9987 3132277 CMLD2_000768 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc2ccc(OC)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H18 compound treatment 1.00240318E8 -1200000.0 -0.1 9.6652161E7 -622000.0 -0.05 -0.1116 -0.955 3012416 CMLD2_000769 CCCNC(=O)OC[C@H]1O[C@H](CCON=C(C)C)C=C[C@@H]1Oc2ccc(OC)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H19 mock treatment 1.04886364E8 3450000.0 0.3 1.03064438E8 5790000.0 0.51 0.569 0.9679 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H20 mock treatment 1.00981373E8 -456000.0 -0.04 9.1063514E7 -6210000.0 -0.54 -0.4121 -0.7563 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H21 compound treatment 1.13209711E8 1.18E7 1.02 8.9363381E7 -7910000.0 -0.69 0.2295 0.1866 3132278 CMLD2_000770 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H22 compound treatment 9.8726719E7 -2710000.0 -0.23 8.8241608E7 -9030000.0 -0.79 -0.7245 -0.8788 3012418 CMLD2_000771 CO[C@H]1[C@H](C)/C(=C\CCOCC#CC)/c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H23 mock treatment 1.12097674E8 1.07E7 0.92 1.02696137E8 5420000.0 0.47 0.9867 0.9525 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 H24 mock treatment 1.08164427E8 6730000.0 0.58 1.01506478E8 4230000.0 0.37 0.6728 0.9764 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I01 compound treatment 1.11240727E8 9800000.0 0.85 1.03889263E8 6620000.0 0.58 1.0082 0.9828 3132279 CMLD2_000772 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I02 compound treatment 1.0753712E8 6100000.0 0.53 9.1082606E7 -6190000.0 -0.54 -0.0106 -0.014 3012419 CMLD2_000773 C[C@@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I03 compound treatment 1.04288347E8 2850000.0 0.25 1.01352687E8 4080000.0 0.36 0.4266 0.9836 3132280 CMLD2_000774 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)c6ccccc6)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I04 compound treatment 1.01244101E8 -193000.0 -0.02 9.7030073E7 -244000.0 -0.02 -0.0269 -0.9926 3132281 CMLD2_000775 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I05 mock treatment 1.00677471E8 -760000.0 -0.07 9.9385741E7 2110000.0 0.18 0.0843 0.4298 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I06 mock treatment 9.63496E7 -5090000.0 -0.44 9.5736702E7 -1540000.0 -0.13 -0.4058 -0.8831 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I07 compound treatment 9.8830514E7 -2610000.0 -0.23 9.8301857E7 1030000.0 0.09 -0.0956 -0.3942 3012420 CMLD2_000776 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I08 compound treatment 9.6642743E7 -4790000.0 -0.41 9.4975249E7 -2300000.0 -0.2 -0.4351 -0.945 3132282 CMLD2_000777 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)cc2)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I09 compound treatment 9.7325273E7 -4110000.0 -0.36 9.3743523E7 -3530000.0 -0.31 -0.4696 -0.9976 3012421 CMLD2_000778 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I10 compound treatment 9.4388514E7 -7050000.0 -0.61 9.2958132E7 -4320000.0 -0.38 -0.6976 -0.9736 3132283 CMLD2_000779 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I11 compound treatment 9.5028173E7 -6410000.0 -0.55 9.3235695E7 -4040000.0 -0.35 -0.6413 -0.9765 3012422 CMLD2_000780 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@H]4O[C@@H](C=C[C@@H]4Oc5ccc(OC)cc5)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I12 compound treatment 9.1385685E7 -1.01E7 -0.87 9.1462346E7 -5810000.0 -0.51 -0.9735 -0.9675 3012473 CMLD2_000781 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I13 compound treatment 8.4915935E7 -1.65E7 -1.43 8.2978947E7 -1.43E7 -1.25 -1.8936 -0.9978 3132284 CMLD2_000782 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cc(no6)c7c(C)cc(C)cc7C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I14 compound treatment 9.4752824E7 -6680000.0 -0.58 9.3401188E7 -3870000.0 -0.34 -0.6479 -0.9678 3012475 CMLD2_000783 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I15 compound treatment 9.6995844E7 -4440000.0 -0.38 9.4567149E7 -2710000.0 -0.24 -0.4387 -0.9732 3132285 CMLD2_000784 CCc1cc2CN(CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I16 compound treatment 9.1604248E7 -9830000.0 -0.85 9.2798039E7 -4480000.0 -0.39 -0.8775 -0.9382 3012476 CMLD2_000785 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I17 compound treatment 1.00485883E8 -951000.0 -0.08 9.6530507E7 -743000.0 -0.07 -0.1041 -0.9933 3132408 CMLD2_000786 CO[C@H](/C=N/OCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I18 compound treatment 9.6089376E7 -5350000.0 -0.46 9.3823874E7 -3450000.0 -0.3 -0.5401 -0.9788 3012477 CMLD2_000787 CC(=NOCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I19 compound treatment 1.01029038E8 -408000.0 -0.04 9.7968652E7 695000.0 0.06 0.0181 0.2573 3132409 CMLD2_000788 CO/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I20 mock treatment 9.9992936E7 -1440000.0 -0.12 9.784077E7 567000.0 0.05 -0.0531 -0.3956 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I21 mock treatment 1.02227723E8 791000.0 0.07 9.9807277E7 2530000.0 0.22 0.2051 0.8839 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I22 mock treatment 1.03077528E8 1640000.0 0.14 9.8836412E7 1560000.0 0.14 0.1969 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I23 mock treatment 8.5571911E7 -1.59E7 -1.37 9.9221169E7 1950000.0 0.17 -0.8484 -0.6144 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 I24 mock treatment 9.7281435E7 -4160000.0 -0.36 1.02154582E8 4880000.0 0.43 0.0482 0.0865 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J01 compound treatment 1.10737217E8 9300000.0 0.8 9.9710512E7 2440000.0 0.21 0.7188 0.8649 3132410 CMLD2_000789 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)CCC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J02 compound treatment 1.05954326E8 4520000.0 0.39 9.7419453E7 146000.0 0.01 0.2849 0.7298 3012478 CMLD2_000790 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J03 compound treatment 1.02390692E8 954000.0 0.08 9.9646938E7 2370000.0 0.21 0.2051 0.918 3132411 CMLD2_000791 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J04 compound treatment 9.5851447E7 -5590000.0 -0.48 8.9933023E7 -7340000.0 -0.64 -0.7954 -0.99 3132412 CMLD2_000792 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J05 mock treatment 1.01447132E8 10000.0 0.0 9.6983829E7 -290000.0 -0.03 -0.0173 -0.6825 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J06 mock treatment 9.0347385E7 -1.11E7 -0.96 8.8410869E7 -8860000.0 -0.78 -1.2258 -0.9945 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J07 compound treatment 1.0250608E8 1070000.0 0.09 9.7947614E7 674000.0 0.06 0.107 0.9766 3012479 CMLD2_000793 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J08 compound treatment 9.0844552E7 -1.06E7 -0.91 9.0553951E7 -6720000.0 -0.59 -1.0628 -0.9772 3012480 CMLD2_000794 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)COCc3ccco3)cc2)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J09 compound treatment 9.6542778E7 -4890000.0 -0.42 9.3995098E7 -3280000.0 -0.29 -0.5018 -0.9822 3132413 CMLD2_000795 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J10 compound treatment 9.0779514E7 -1.07E7 -0.92 8.911365E7 -8160000.0 -0.71 -1.1559 -0.9921 3132414 CMLD2_000796 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCCc5nc(C)c(C)cc45)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J11 compound treatment 9.3845158E7 -7590000.0 -0.66 9.1986042E7 -5290000.0 -0.46 -0.7909 -0.9854 3132415 CMLD2_000797 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(CC)C4=O)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J12 compound treatment 8.6236893E7 -1.52E7 -1.31 9.0200946E7 -7070000.0 -0.62 -1.366 -0.9411 3012481 CMLD2_000798 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J13 compound treatment 9.4803148E7 -6630000.0 -0.57 9.2442746E7 -4830000.0 -0.42 -0.7041 -0.9888 3132416 CMLD2_000799 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J14 compound treatment 9.4363399E7 -7070000.0 -0.61 8.9991421E7 -7280000.0 -0.64 -0.8827 -0.9998 3012482 CMLD2_000800 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J15 compound treatment 9.8186089E7 -3250000.0 -0.28 9.6597208E7 -676000.0 -0.06 -0.2404 -0.8378 3132417 CMLD2_000801 CCc1cc2CN(CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J16 compound treatment 9.110861E7 -1.03E7 -0.89 9.0377841E7 -6900000.0 -0.6 -1.0576 -0.9819 3012484 CMLD2_000802 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J17 compound treatment 1.01676188E8 239000.0 0.02 9.7270154E7 -3550.0 0.0 0.0144 0.6964 3132418 CMLD2_000803 CO[C@H](/C=N/OC(C)CN1CCCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J18 compound treatment 9.9037942E7 -2400000.0 -0.21 9.3047964E7 -4230000.0 -0.37 -0.408 -0.9625 3012486 CMLD2_000804 CC(CN1CCCCc2nc(C)c(C)cc12)ON=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J19 compound treatment 1.02943301E8 1510000.0 0.13 9.875253E7 1480000.0 0.13 0.1835 1.0 3132419 CMLD2_000805 CO/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J20 mock treatment 9.9231089E7 -2210000.0 -0.19 9.4830637E7 -2440000.0 -0.21 -0.2859 -0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J21 mock treatment 1.05665464E8 4230000.0 0.37 9.9495051E7 2220000.0 0.19 0.3957 0.9564 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J22 mock treatment 1.05825213E8 4390000.0 0.38 9.7401325E7 128000.0 0.01 0.2759 0.7276 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J23 mock treatment 7.4363167E7 -2.71E7 -2.34 1.02502018E8 5230000.0 0.46 -1.33 -0.5582 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 J24 mock treatment 9.2724049E7 -8710000.0 -0.75 1.00247454E8 2970000.0 0.26 -0.3481 -0.4372 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K01 compound treatment 1.09661697E8 8220000.0 0.71 9.6186975E7 -1090000.0 -0.1 0.4351 0.607 3132420 CMLD2_000806 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K02 compound treatment 1.07817722E8 6380000.0 0.55 8.7616909E7 -9660000.0 -0.85 -0.2079 -0.2061 3012487 CMLD2_000807 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K03 compound treatment 1.08479587E8 7040000.0 0.61 9.9945304E7 2670000.0 0.23 0.5954 0.9137 3132421 CMLD2_000808 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K04 compound treatment 1.02024876E8 588000.0 0.05 9.6324309E7 -949000.0 -0.08 -0.0229 -0.2347 3132422 CMLD2_000809 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K05 compound treatment 1.0745246E8 6020000.0 0.52 9.9976212E7 2700000.0 0.24 0.5346 0.9365 3012488 CMLD2_000810 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K06 compound treatment 9.971379E7 -1720000.0 -0.15 9.5725166E7 -1550000.0 -0.14 -0.2011 -0.9989 3132423 CMLD2_000811 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K07 mock treatment 9.8663112E7 -2770000.0 -0.24 9.2964513E7 -4310000.0 -0.38 -0.4361 -0.976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K08 mock treatment 9.3180969E7 -8260000.0 -0.71 9.1225153E7 -6050000.0 -0.53 -0.8785 -0.9892 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K09 compound treatment 9.3376688E7 -8060000.0 -0.7 9.4229445E7 -3040000.0 -0.27 -0.6807 -0.9131 3132424 CMLD2_000812 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K10 compound treatment 9.4353796E7 -7080000.0 -0.61 8.9015073E7 -8260000.0 -0.72 -0.9437 -0.9966 3011824 CMLD2_000813 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCc5nc(C)c(C)cc45)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K11 compound treatment 9.2334726E7 -9100000.0 -0.79 7.6289639E7 -2.1E7 -1.84 -1.8545 -0.9283 3132425 CMLD2_000814 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K12 compound treatment 8.1433894E7 -2.0E7 -1.73 7.6077257E7 -2.12E7 -1.86 -2.5334 -0.9994 3132426 CMLD2_000815 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)c8ccccc8)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K13 compound treatment 9.8488825E7 -2950000.0 -0.25 8.8589944E7 -8680000.0 -0.76 -0.7175 -0.8951 3011825 CMLD2_000816 CC(=O)OC[C@H]1O[C@@H](O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K14 compound treatment 9.9398752E7 -2040000.0 -0.18 9.5114941E7 -2160000.0 -0.19 -0.2581 -0.9994 3132547 CMLD2_000817 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K15 mock treatment 8.2859075E7 -1.86E7 -1.6 7.9999333E7 -1.73E7 -1.51 -2.2037 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K16 mock treatment 9.676369E7 -4670000.0 -0.4 8.0196993E7 -1.71E7 -1.49 -1.3422 -0.867 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K17 compound treatment 1.04455046E8 3020000.0 0.26 9.6572834E7 -701000.0 -0.06 0.1409 0.5263 3011826 CMLD2_000818 CO[C@H](/C=N/OC(C)CN1CCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K18 compound treatment 1.01141243E8 -296000.0 -0.03 9.7542549E7 269000.0 0.02 -0.0014 -0.0412 3132548 CMLD2_000819 CC(CN1CCCc2nc(C)c(C)cc12)ON=C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K19 compound treatment 1.00460233E8 -977000.0 -0.08 9.6033392E7 -1240000.0 -0.11 -0.1364 -0.9922 3011827 CMLD2_000820 CO/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K20 compound treatment 1.05100996E8 3660000.0 0.32 9.9297542E7 2020000.0 0.18 0.349 0.9624 3131977 CMLD2_000821 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K21 compound treatment 1.04858852E8 3420000.0 0.3 1.04495684E8 7220000.0 0.63 0.6559 0.9401 3132549 CMLD2_000822 C[C@@H]1CC[C@@H]2N(C[C@H](Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K22 compound treatment 1.02291003E8 854000.0 0.07 9.8844356E7 1570000.0 0.14 0.1494 0.9574 3132550 CMLD2_000823 CCO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K23 mock treatment 1.05964496E8 4530000.0 0.39 9.5454261E7 -1820000.0 -0.16 0.1639 0.3882 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 K24 mock treatment 1.07873954E8 6440000.0 0.56 1.03834948E8 6560000.0 0.57 0.7992 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L01 compound treatment 8.7865716E7 -1.36E7 -1.17 9.1572515E7 -5700000.0 -0.5 -1.1817 -0.9276 3011828 CMLD2_000824 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L02 compound treatment 1.01267585E8 -170000.0 -0.01 8.5781133E7 -1.15E7 -1.01 -0.7216 -0.7173 3132551 CMLD2_000825 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L03 compound treatment 1.11495077E8 1.01E7 0.87 1.05163719E8 7890000.0 0.69 1.1026 0.9935 3011829 CMLD2_000826 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L04 compound treatment 9.7328309E7 -4110000.0 -0.35 9.2579576E7 -4690000.0 -0.41 -0.5414 -0.9973 3132552 CMLD2_000827 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L05 compound treatment 1.00275971E8 -1160000.0 -0.1 1.01024041E8 3750000.0 0.33 0.1612 0.4696 3132553 CMLD2_000828 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L06 compound treatment 9.9838697E7 -1600000.0 -0.14 9.2402308E7 -4870000.0 -0.43 -0.3991 -0.8906 3011830 CMLD2_000829 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L07 mock treatment 9.8306055E7 -3130000.0 -0.27 1.00053863E8 2780000.0 0.24 -0.0192 -0.0527 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L08 mock treatment 9.4652812E7 -6780000.0 -0.59 9.2146068E7 -5130000.0 -0.45 -0.7317 -0.9913 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L09 compound treatment 9.7552471E7 -3880000.0 -0.34 9.611585E7 -1160000.0 -0.1 -0.3089 -0.8813 3132554 CMLD2_000830 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)COCc2ccco2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L10 compound treatment 9.2258053E7 -9180000.0 -0.79 8.6746544E7 -1.05E7 -0.92 -1.2121 -0.9972 3011831 CMLD2_000831 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L11 compound treatment 9.293097E7 -8510000.0 -0.73 9.4852871E7 -2420000.0 -0.21 -0.6693 -0.8753 3132555 CMLD2_000832 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCCc5nc(C)c(C)cc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L12 compound treatment 8.7778902E7 -1.37E7 -1.18 8.6211914E7 -1.11E7 -0.97 -1.5187 -0.9952 3132556 CMLD2_000833 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1Oc7ccc(OC)cc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L13 compound treatment 8.4851536E7 -1.66E7 -1.43 9.0718703E7 -6550000.0 -0.57 -1.4186 -0.9193 3011832 CMLD2_000834 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L14 compound treatment 8.8849382E7 -1.26E7 -1.09 9.5025455E7 -2250000.0 -0.2 -0.9079 -0.8217 3132557 CMLD2_000835 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L15 mock treatment 1.00331552E8 -1110000.0 -0.1 7.1300904E7 -2.6E7 -2.27 -1.6748 -0.7362 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L16 mock treatment 9.8415341E7 -3020000.0 -0.26 7.8707525E7 -1.86E7 -1.62 -1.3335 -0.8103 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L17 compound treatment 1.01446926E8 9830.0 0.0 9.2235879E7 -5040000.0 -0.44 -0.3112 -0.7057 3132558 CMLD2_000836 CO[C@H](/C=N/OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L18 compound treatment 9.803032E7 -3410000.0 -0.29 9.4666373E7 -2610000.0 -0.23 -0.3694 -0.9921 3011833 CMLD2_000837 CC(=NOC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L19 compound treatment 1.00862386E8 -575000.0 -0.05 1.03820127E8 6550000.0 0.57 0.37 0.6434 3011834 CMLD2_000838 CO/N=C/c1ccc(cc1)C(=O)N2[C@@H](CC[C@H](C)[C@H]2c3ccc(C)cc3)C(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L20 compound treatment 1.05349805E8 3910000.0 0.34 9.8696681E7 1420000.0 0.12 0.327 0.908 3132559 CMLD2_000839 CCC(=O)[C@]1(O)[C@H]2CCOC(=O)C2=C3N(Cc4ccccc4)C(=C([C@H](N3C1=O)c5ccccc5)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L21 compound treatment 1.02792218E8 1360000.0 0.12 1.01728594E8 4450000.0 0.39 0.3585 0.8806 3132529 CMLD2_000840 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L22 compound treatment 1.05766038E8 4330000.0 0.37 9.8934263E7 1660000.0 0.15 0.3672 0.9152 3011835 CMLD2_000841 CO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)C(=O)C)[C@@H](C)[C@H](OC)c1ccccc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L23 mock treatment 1.05709418E8 4270000.0 0.37 1.01084893E8 3810000.0 0.33 0.4968 0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 L24 mock treatment 1.06313119E8 4880000.0 0.42 1.02054054E8 4780000.0 0.42 0.5936 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M01 compound treatment 1.0898411E8 7550000.0 0.65 9.7779274E7 506000.0 0.04 0.4922 0.7534 3132560 CMLD2_000842 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)CCC[C@H]1C)[C@@H](O)C=C2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M02 compound treatment 1.05642481E8 4210000.0 0.36 1.03098209E8 5820000.0 0.51 0.6173 0.9862 3011836 CMLD2_000843 C[C@H]/1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C\C=C1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M03 compound treatment 9.9937472E7 -1500000.0 -0.13 9.3629355E7 -3640000.0 -0.32 -0.3171 -0.9212 3132561 CMLD2_000844 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M04 compound treatment 1.03565642E8 2130000.0 0.18 9.8605975E7 1330000.0 0.12 0.2124 0.9759 3132562 CMLD2_000845 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M05 compound treatment 8.2880737E7 -1.86E7 -1.6 9.7032267E7 -241000.0 -0.02 -1.1483 -0.7164 3011870 CMLD2_000846 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M06 compound treatment 8.1992525E7 -1.94E7 -1.68 8.990356E7 -7370000.0 -0.65 -1.6437 -0.9136 3132563 CMLD2_000847 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M07 compound treatment 9.6118899E7 -5320000.0 -0.46 1.00187853E8 2910000.0 0.26 -0.1445 -0.275 3011871 CMLD2_000848 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M08 compound treatment 9.1601258E7 -9840000.0 -0.85 9.1740153E7 -5530000.0 -0.48 -0.9432 -0.9645 3132564 CMLD2_000849 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)cc2)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M09 mock treatment 9.1504884E7 -9930000.0 -0.86 8.6768417E7 -1.05E7 -0.92 -1.2567 -0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M10 mock treatment 9.6467666E7 -4970000.0 -0.43 9.0464146E7 -6810000.0 -0.6 -0.7249 -0.987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M11 compound treatment 7.9480774E7 -2.2E7 -1.9 8.6673063E7 -1.06E7 -0.93 -1.997 -0.9459 3011872 CMLD2_000850 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCc5nc(C)c(C)cc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M12 compound treatment 6.9782873E7 -3.17E7 -2.73 7.6899671E7 -2.04E7 -1.78 -3.1941 -0.9786 3132565 CMLD2_000851 CC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M13 mock treatment 9.4332823E7 -7100000.0 -0.61 9.3003968E7 -4270000.0 -0.37 -0.6981 -0.9717 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M14 mock treatment 9.497414E7 -6460000.0 -0.56 8.6214201E7 -1.11E7 -0.97 -1.0791 -0.9658 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M15 compound treatment 7.8746996E7 -2.27E7 -1.96 9.7069871E7 -204000.0 -0.02 -1.3984 -0.7135 3132566 CMLD2_000852 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M16 compound treatment 7.0804657E7 -3.06E7 -2.65 9.4808409E7 -2470000.0 -0.22 -2.0234 -0.7622 3011873 CMLD2_000853 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M17 compound treatment 9.9735076E7 -1700000.0 -0.15 8.7500055E7 -9770000.0 -0.86 -0.7088 -0.8167 3130490 CMLD2_000854 CO[C@H](/C=N/O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M18 compound treatment 9.8311402E7 -3130000.0 -0.27 9.4068097E7 -3210000.0 -0.28 -0.3893 -0.9998 3011875 CMLD2_000855 CC(=NOC1C=C[C@@H](CC=C)O[C@@H]1CO)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M19 compound treatment 9.1350249E7 -1.01E7 -0.87 9.8371564E7 1100000.0 0.1 -0.5481 -0.6253 3130491 CMLD2_000856 CO/N=C/[C@@H](NS(=O)(=O)c1ccc(C)cc1)[C@H](C)\C=C\CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M20 compound treatment 9.9777024E7 -1660000.0 -0.14 8.7343191E7 -9930000.0 -0.87 -0.7159 -0.8128 3132404 CMLD2_000857 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M21 compound treatment 1.04717871E8 3280000.0 0.28 1.04993284E8 7720000.0 0.68 0.6781 0.9256 3011876 CMLD2_000858 C[C@H]1CC[C@@H]2N(C[C@@H](CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M22 compound treatment 9.119494E7 -1.02E7 -0.88 1.00963658E8 3690000.0 0.32 -0.3972 -0.4218 3130492 CMLD2_000859 CO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1ccccc1Br 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M23 mock treatment 1.06052172E8 4620000.0 0.4 9.8487098E7 1210000.0 0.11 0.357 0.8653 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 M24 mock treatment 1.06895868E8 5460000.0 0.47 1.00378112E8 3100000.0 0.27 0.5255 0.9657 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N01 compound treatment 1.12677451E8 1.12E7 0.97 1.0532791E8 8050000.0 0.7 1.1849 0.9876 3130493 CMLD2_000860 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)CCC[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N02 compound treatment 1.06508368E8 5070000.0 0.44 9.2554371E7 -4720000.0 -0.41 0.0177 0.0294 3011877 CMLD2_000861 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N03 compound treatment 1.00215664E8 -1220000.0 -0.11 9.9098408E7 1820000.0 0.16 0.0383 0.2002 3130494 CMLD2_000862 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)c5ccccc5)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N04 compound treatment 1.02393475E8 956000.0 0.08 9.84938E7 1220000.0 0.11 0.1339 0.992 3130495 CMLD2_000863 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N05 compound treatment 8.4606448E7 -1.68E7 -1.45 9.3973415E7 -3300000.0 -0.29 -1.2322 -0.8313 3011878 CMLD2_000864 CC(=O)OC[C@H]1O[C@H](C/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N06 compound treatment 7.5814225E7 -2.56E7 -2.21 9.2739353E7 -4530000.0 -0.4 -1.8455 -0.8208 3130496 CMLD2_000865 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N07 compound treatment 1.02799184E8 1360000.0 0.12 9.7040552E7 -233000.0 -0.02 0.0688 0.5759 3011879 CMLD2_000866 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N08 compound treatment 8.698143E7 -1.45E7 -1.25 8.0408678E7 -1.69E7 -1.48 -1.9266 -0.9965 3130497 CMLD2_000867 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N09 mock treatment 9.4948914E7 -6490000.0 -0.56 9.5811188E7 -1460000.0 -0.13 -0.4868 -0.8468 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N10 mock treatment 9.4195478E7 -7240000.0 -0.63 9.0363492E7 -6910000.0 -0.6 -0.8699 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N11 compound treatment 7.9210771E7 -2.22E7 -1.92 7.571084E7 -2.16E7 -1.89 -2.6919 -1.0 3011881 CMLD2_000868 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N12 compound treatment 6.8624385E7 -3.28E7 -2.83 7.9051935E7 -1.82E7 -1.59 -3.1317 -0.963 3130498 CMLD2_000869 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N13 mock treatment 9.9893207E7 -1540000.0 -0.13 9.286367E7 -4410000.0 -0.39 -0.3672 -0.8993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N14 mock treatment 9.4376504E7 -7060000.0 -0.61 8.5946241E7 -1.13E7 -0.99 -1.1322 -0.9728 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N15 compound treatment 7.3921566E7 -2.75E7 -2.38 9.5544312E7 -1730000.0 -0.15 -1.7875 -0.7506 3130499 CMLD2_000870 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N16 compound treatment 7.6647446E7 -2.48E7 -2.14 9.1412794E7 -5860000.0 -0.51 -1.8767 -0.8524 3011882 CMLD2_000871 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N17 compound treatment 1.04384162E8 2950000.0 0.25 8.709238E7 -1.02E7 -0.89 -0.4501 -0.4857 3130500 CMLD2_000872 CO[C@H](/C=N/OC[C@@H](O)COCc1ccco1)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N18 compound treatment 8.8005396E7 -1.34E7 -1.16 9.2985354E7 -4290000.0 -0.38 -1.0857 -0.8904 3011884 CMLD2_000873 CC(=NOC[C@@H](O)COCc1ccco1)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N19 compound treatment 1.03306678E8 1870000.0 0.16 1.00625177E8 3350000.0 0.29 0.3216 0.9605 3130501 CMLD2_000874 CO/N=C\1/[C@H](O)[C@H](Oc2ccc(OC)cc12)c3cccc(OC)c3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N20 compound treatment 9.9290913E7 -2150000.0 -0.19 8.9859331E7 -7410000.0 -0.65 -0.5899 -0.8741 3131849 CMLD2_000875 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N21 compound treatment 8.9637276E7 -1.18E7 -1.02 1.04797686E8 7520000.0 0.66 -0.2551 -0.2102 3011885 CMLD2_000876 C[C@@H]1CC[C@@H]2N(C[C@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N22 compound treatment 9.7697974E7 -3740000.0 -0.32 1.02162311E8 4890000.0 0.43 0.0742 0.1384 3130502 CMLD2_000877 CO[C@@H]([C@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)/C=C/CC(=O)OC)C2CCCCC2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N23 mock treatment 1.05451629E8 4010000.0 0.35 9.1888822E7 -5380000.0 -0.47 -0.0881 -0.1505 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 N24 mock treatment 9.9694769E7 -1740000.0 -0.15 1.02711686E8 5440000.0 0.48 0.2301 0.461 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O01 compound treatment 1.03270796E8 1830000.0 0.16 1.01342509E8 4070000.0 0.36 0.3638 0.9334 3011886 CMLD2_000878 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O02 compound treatment 1.02873794E8 1440000.0 0.12 9.6415506E7 -858000.0 -0.08 0.0346 0.2388 3130503 CMLD2_000879 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O03 compound treatment 8.9801499E7 -1.16E7 -1.0 1.00398779E8 3130000.0 0.27 -0.5172 -0.4966 3130504 CMLD2_000880 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O04 compound treatment 8.1406147E7 -2.0E7 -1.73 9.4562618E7 -2710000.0 -0.24 -1.3912 -0.7966 3130505 CMLD2_000881 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O05 compound treatment 1.04115907E8 2680000.0 0.23 9.7309631E7 35900.0 0.0 0.1658 0.7167 3130506 CMLD2_000882 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)COCc2ccco2)C=C[C@@H]1OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O06 compound treatment 1.0697751E8 5540000.0 0.48 1.05735189E8 8460000.0 0.74 0.862 0.9777 3011921 CMLD2_000883 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O07 compound treatment 1.02198443E8 761000.0 0.07 9.6327722E7 -946000.0 -0.08 -0.012 -0.1139 3130507 CMLD2_000884 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O08 compound treatment 9.9747272E7 -1690000.0 -0.15 9.3762328E7 -3510000.0 -0.31 -0.3205 -0.9421 3130508 CMLD2_000885 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)cc2)c5ccc(C)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O09 compound treatment 8.4154046E7 -1.73E7 -1.49 9.2752183E7 -4520000.0 -0.4 -1.3354 -0.8647 3011922 CMLD2_000886 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O10 compound treatment 9.2895476E7 -8540000.0 -0.74 8.7108388E7 -1.02E7 -0.89 -1.1507 -0.9957 3130509 CMLD2_000887 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O11 mock treatment 9.7284981E7 -4150000.0 -0.36 8.8648448E7 -8630000.0 -0.75 -0.7874 -0.9421 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O12 mock treatment 8.9153847E7 -1.23E7 -1.06 8.735725E7 -9920000.0 -0.87 -1.3639 -0.995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O13 compound treatment 7.9207404E7 -2.22E7 -1.92 9.1868525E7 -5410000.0 -0.47 -1.6922 -0.8557 3011925 CMLD2_000888 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/[C@@H](C)[C@H](OCc3ccccc3)C(C)C)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O14 compound treatment 7.1917249E7 -2.95E7 -2.55 8.8110516E7 -9160000.0 -0.8 -2.37 -0.8867 3130636 CMLD2_000889 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O15 compound treatment 9.9881268E7 -1560000.0 -0.13 9.1813695E7 -5460000.0 -0.48 -0.4329 -0.8721 3011927 CMLD2_000890 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O16 compound treatment 9.4845757E7 -6590000.0 -0.57 8.9732006E7 -7540000.0 -0.66 -0.8693 -0.9973 3130637 CMLD2_000891 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@@H]6COC[C@H]6O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O17 compound treatment 9.9465254E7 -1970000.0 -0.17 9.6324925E7 -949000.0 -0.08 -0.1791 -0.9455 3130638 CMLD2_000892 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@@H]2COC[C@H]2O)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O18 compound treatment 9.781252E7 -3620000.0 -0.31 9.2635977E7 -4640000.0 -0.41 -0.5084 -0.9918 3011928 CMLD2_000893 C[C@@H](ON=C(C)C)c1cn(nn1)[C@@H]2COC[C@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O19 compound treatment 1.03184724E8 1750000.0 0.15 9.6891753E7 -382000.0 -0.03 0.0831 0.5375 3130639 CMLD2_000894 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O20 compound treatment 1.02963642E8 1530000.0 0.13 9.7961994E7 688000.0 0.06 0.1358 0.937 3011929 CMLD2_000895 CCN1C(=C([C@H](N2C(=O)[C@@](O)(CC(=C12)C(=O)C)C(=O)OC)c3ccccc3)C(=O)OC)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O21 compound treatment 1.03388468E8 1950000.0 0.17 9.785848E7 585000.0 0.05 0.1554 0.8821 3130640 CMLD2_000896 C[C@@H]1CC[C@@H]2N(C[C@@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O22 mock treatment 1.04523052E8 3090000.0 0.27 9.7776237E7 503000.0 0.04 0.2196 0.8128 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O23 mock treatment 1.01781862E8 345000.0 0.03 1.02623774E8 5350000.0 0.47 0.3521 0.7506 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 O24 mock treatment 1.03875821E8 2440000.0 0.21 1.01428573E8 4150000.0 0.36 0.4061 0.9663 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P01 compound treatment 9.4541476E7 -6900000.0 -0.6 9.9074264E7 1800000.0 0.16 -0.3097 -0.5027 3011930 CMLD2_000897 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P02 compound treatment 1.01515998E8 78900.0 0.01 9.2827649E7 -4450000.0 -0.39 -0.2703 -0.6946 3130641 CMLD2_000898 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P03 compound treatment 8.304491E7 -1.84E7 -1.59 9.7520367E7 247000.0 0.02 -1.108 -0.6974 3130642 CMLD2_000899 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)c4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P04 compound treatment 7.4846426E7 -2.66E7 -2.3 9.5975348E7 -1300000.0 -0.11 -1.7044 -0.7412 3130643 CMLD2_000900 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@@H]5COC[C@H]5O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P05 compound treatment 1.04479892E8 3040000.0 0.26 9.6428412E7 -845000.0 -0.07 0.1335 0.4891 3011932 CMLD2_000901 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P06 compound treatment 1.02980935E8 1540000.0 0.13 9.3646908E7 -3630000.0 -0.32 -0.1302 -0.378 3130644 CMLD2_000902 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P07 compound treatment 1.04342739E8 2910000.0 0.25 9.5243102E7 -2030000.0 -0.18 0.0518 0.1684 3011933 CMLD2_000903 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P08 compound treatment 9.6283183E7 -5150000.0 -0.45 8.9510928E7 -7760000.0 -0.68 -0.7952 -0.979 3130645 CMLD2_000904 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)cc2)c4ccc(C)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P09 compound treatment 9.8940842E7 -2500000.0 -0.22 9.3086525E7 -4190000.0 -0.37 -0.4116 -0.968 3011935 CMLD2_000905 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P10 compound treatment 9.4377326E7 -7060000.0 -0.61 8.5066605E7 -1.22E7 -1.07 -1.1866 -0.9646 3130646 CMLD2_000906 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)COCc4ccco4)/[C@@H]2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P11 mock treatment 9.6238664E7 -5200000.0 -0.45 8.587197E7 -1.14E7 -1.0 -1.0231 -0.935 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P12 mock treatment 9.4342392E7 -7090000.0 -0.61 8.5129852E7 -1.21E7 -1.06 -1.1848 -0.9658 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P13 compound treatment 7.585486E7 -2.56E7 -2.21 8.210959E7 -1.52E7 -1.33 -2.5008 -0.9703 3130647 CMLD2_000907 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P14 compound treatment 7.6931323E7 -2.45E7 -2.12 8.8804958E7 -8470000.0 -0.74 -2.0208 -0.9011 3011936 CMLD2_000908 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P15 compound treatment 1.02744079E8 1310000.0 0.11 9.6545493E7 -728000.0 -0.06 0.0348 0.2681 3130648 CMLD2_000909 CCc1cc2CN(CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)CCc2nc1CC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P16 compound treatment 9.3620831E7 -7820000.0 -0.68 8.8896172E7 -8380000.0 -0.73 -0.9958 -0.9992 3130649 CMLD2_000910 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P17 compound treatment 1.02694924E8 1260000.0 0.11 9.7716443E7 443000.0 0.04 0.1042 0.9036 3011937 CMLD2_000911 CO[C@H](/C=N/O[C@@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P18 compound treatment 9.7762141E7 -3670000.0 -0.32 9.1255697E7 -6020000.0 -0.53 -0.5969 -0.9706 3130650 CMLD2_000912 C[C@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P19 compound treatment 1.06376432E8 4940000.0 0.43 9.7775026E7 501000.0 0.04 0.3327 0.7757 3011939 CMLD2_000913 CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P20 compound treatment 9.95353E7 -1900000.0 -0.16 9.4610091E7 -2660000.0 -0.23 -0.281 -0.9853 3131985 CMLD2_000914 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P21 compound treatment 1.03996738E8 2560000.0 0.22 9.8867775E7 1590000.0 0.14 0.255 0.9754 3130651 CMLD2_000915 C[C@@H]1CC[C@@H]2N(C[C@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P22 mock treatment 1.05324905E8 3890000.0 0.34 9.9039047E7 1770000.0 0.15 0.3467 0.9379 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P23 mock treatment 1.05474106E8 4040000.0 0.35 1.04900622E8 7630000.0 0.67 0.7185 0.9541 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2111 P24 mock treatment 1.06423431E8 4990000.0 0.43 1.01489593E8 4220000.0 0.37 0.5654 0.997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A01 compound treatment 1.04841342E8 3220000.0 0.28 1.05507448E8 7960000.0 0.7 0.6889 0.9189 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A02 compound treatment 1.11098782E8 9480000.0 0.82 9.69495E7 -601000.0 -0.05 0.5415 0.6603 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A03 compound treatment 1.11339375E8 9720000.0 0.84 1.00997224E8 3450000.0 0.3 0.8067 0.9046 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A04 compound treatment 1.07127653E8 5500000.0 0.48 1.03181048E8 5630000.0 0.49 0.6846 0.9998 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A05 compound treatment 9.5993792E7 -5630000.0 -0.49 1.02874228E8 5320000.0 0.47 -0.0144 -0.0213 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A06 compound treatment 1.07093648E8 5470000.0 0.47 9.8455757E7 905000.0 0.08 0.3901 0.8143 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A07 compound treatment 1.03308066E8 1680000.0 0.15 1.08699636E8 1.11E7 0.98 0.7928 0.8037 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A08 compound treatment 9.8346515E7 -3280000.0 -0.28 1.04027112E8 6480000.0 0.57 0.2007 0.3167 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A09 compound treatment 8.9503135E7 -1.21E7 -1.05 9.7084194E7 -467000.0 -0.04 -0.7691 -0.7341 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A10 compound treatment 1.02677277E8 1050000.0 0.09 9.4429225E7 -3120000.0 -0.27 -0.1288 -0.4472 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A11 compound treatment 8.997249E7 -1.17E7 -1.01 8.7237383E7 -1.03E7 -0.9 -1.3498 -0.9985 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A12 compound treatment 9.8539077E7 -3080000.0 -0.27 1.05238154E8 7690000.0 0.67 0.2874 0.3971 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A13 mock treatment 9.6580969E7 -5040000.0 -0.44 1.00641508E8 3090000.0 0.27 -0.1167 -0.2276 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A14 mock treatment 1.00087728E8 -1540000.0 -0.13 9.4857516E7 -2690000.0 -0.24 -0.2604 -0.963 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A15 compound treatment 1.0060065E8 -1020000.0 -0.09 1.0170501E8 4150000.0 0.36 0.1946 0.5202 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A16 compound treatment 1.01510918E8 -112000.0 -0.01 1.04701418E8 7150000.0 0.63 0.4357 0.6961 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A17 compound treatment 9.9059057E7 -2560000.0 -0.22 1.03373262E8 5820000.0 0.51 0.2037 0.3667 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A18 compound treatment 1.03806525E8 2180000.0 0.19 9.5905943E7 -1640000.0 -0.14 0.0316 0.133 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A19 compound treatment 1.02721279E8 1100000.0 0.09 9.9529828E7 1980000.0 0.17 0.1895 0.9598 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A20 compound treatment 1.03990932E8 2370000.0 0.2 1.09053344E8 1.15E7 1.01 0.8564 0.8337 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A21 compound treatment 1.18337588E8 1.67E7 1.44 1.09130847E8 1.16E7 1.01 1.7375 0.985 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A22 compound treatment 1.10035894E8 8410000.0 0.73 1.01972823E8 4420000.0 0.39 0.7875 0.9565 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A23 compound treatment 1.13164471E8 1.15E7 1.0 1.12641035E8 1.51E7 1.32 1.6387 0.9904 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 A24 compound treatment 1.10168619E8 8550000.0 0.74 1.00441132E8 2890000.0 0.25 0.7008 0.8982 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B01 compound treatment 1.09463059E8 7840000.0 0.68 1.01855848E8 4310000.0 0.38 0.7452 0.9617 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B02 compound treatment 1.00672058E8 -951000.0 -0.08 1.05615721E8 8060000.0 0.71 0.441 0.6206 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B03 compound treatment 1.08807911E8 7180000.0 0.62 1.04965109E8 7410000.0 0.65 0.8976 0.9998 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B04 compound treatment 1.06635105E8 5010000.0 0.43 9.112119E7 -6430000.0 -0.56 -0.0918 -0.1293 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B05 compound treatment 1.03568629E8 1950000.0 0.17 9.7126392E7 -424000.0 -0.04 0.0926 0.5378 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B06 compound treatment 9.9099947E7 -2520000.0 -0.22 1.0823588E8 1.07E7 0.94 0.5071 0.5282 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B07 compound treatment 1.07574197E8 5950000.0 0.51 1.05904159E8 8350000.0 0.73 0.8804 0.9851 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B08 compound treatment 1.03229975E8 1610000.0 0.14 9.3529953E7 -4020000.0 -0.35 -0.1507 -0.3984 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B09 compound treatment 1.03112888E8 1490000.0 0.13 1.00751227E8 3200000.0 0.28 0.289 0.9377 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B10 compound treatment 9.5861859E7 -5760000.0 -0.5 1.01412251E8 3860000.0 0.34 -0.1129 -0.1877 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B11 compound treatment 1.04265807E8 2640000.0 0.23 1.02973328E8 5420000.0 0.47 0.497 0.9437 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B12 compound treatment 9.8302479E7 -3320000.0 -0.29 8.6558028E7 -1.1E7 -0.96 -0.8831 -0.8797 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B13 mock treatment 1.05964359E8 4340000.0 0.37 1.01970039E8 4420000.0 0.39 0.5386 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B14 mock treatment 8.8751404E7 -1.29E7 -1.11 9.8967341E7 1420000.0 0.12 -0.6985 -0.6244 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B15 compound treatment 1.03515781E8 1890000.0 0.16 1.03780906E8 6230000.0 0.55 0.5011 0.8804 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B16 compound treatment 1.03507917E8 1880000.0 0.16 9.1195347E7 -6360000.0 -0.56 -0.2782 -0.48 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B17 compound treatment 1.06769207E8 5150000.0 0.44 1.06023473E8 8470000.0 0.74 0.8386 0.97 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B18 compound treatment 9.7570626E7 -4050000.0 -0.35 1.05180078E8 7630000.0 0.67 0.2246 0.298 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B19 compound treatment 1.11171361E8 9550000.0 0.82 1.0876224E8 1.12E7 0.98 1.277 0.9963 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B20 compound treatment 1.00782204E8 -841000.0 -0.07 9.4271474E7 -3280000.0 -0.29 -0.2543 -0.859 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B21 compound treatment 1.11948468E8 1.03E7 0.89 1.09560202E8 1.2E7 1.05 1.3738 0.9967 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B22 compound treatment 1.01475999E8 -147000.0 -0.01 1.10115823E8 1.26E7 1.1 0.7686 0.6989 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B23 compound treatment 1.17103447E8 1.55E7 1.34 1.11827317E8 1.43E7 1.25 1.8289 0.9994 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 B24 compound treatment 1.10566572E8 8940000.0 0.77 1.08754909E8 1.12E7 0.98 1.2396 0.993 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C01 compound treatment 8.9485911E7 -1.21E7 -1.05 8.5792682E7 -1.18E7 -1.03 -1.4689 -1.0 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C02 compound treatment 1.03863458E8 2240000.0 0.19 9.4697273E7 -2850000.0 -0.25 -0.0398 -0.1258 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C03 compound treatment 1.03948589E8 2330000.0 0.2 9.9449306E7 1900000.0 0.17 0.2595 0.9956 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C04 compound treatment 1.01232896E8 -390000.0 -0.03 1.00547705E8 3000000.0 0.26 0.1616 0.6112 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C05 compound treatment 9.497714E7 -6650000.0 -0.57 9.7888124E7 337000.0 0.03 -0.385 -0.6699 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C06 compound treatment 1.04293351E8 2670000.0 0.23 9.3229705E7 -4320000.0 -0.38 -0.1043 -0.2355 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C07 compound treatment 1.06001718E8 4380000.0 0.38 1.01951773E8 4400000.0 0.39 0.5398 1.0 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C08 compound treatment 9.1283087E7 -1.03E7 -0.89 9.79633E7 412000.0 0.04 -0.606 -0.678 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C09 compound treatment 9.8730803E7 -2890000.0 -0.25 9.427601E7 -3270000.0 -0.29 -0.3793 -0.9977 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C10 compound treatment 1.0204044E8 417000.0 0.04 9.1385277E7 -6170000.0 -0.54 -0.3561 -0.6584 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C11 mock treatment 1.03771195E8 2150000.0 0.19 1.01387778E8 3840000.0 0.34 0.3686 0.9609 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C12 mock treatment 9.9843639E7 -1780000.0 -0.15 1.02730145E8 5180000.0 0.45 0.2118 0.4426 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C13 compound treatment 9.4178913E7 -7440000.0 -0.64 1.00837513E8 3290000.0 0.29 -0.2513 -0.3567 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C14 compound treatment 8.4845584E7 -1.68E7 -1.45 7.6291202E7 -2.13E7 -1.86 -2.3403 -0.9924 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C15 mock treatment 1.04753147E8 3130000.0 0.27 1.01780071E8 4230000.0 0.37 0.4529 0.9881 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C16 mock treatment 9.6444249E7 -5180000.0 -0.45 1.03797253E8 6250000.0 0.55 0.0703 0.0995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C17 compound treatment 9.7202114E7 -4420000.0 -0.38 9.7074598E7 -476000.0 -0.04 -0.2995 -0.7797 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C18 compound treatment 8.754273E7 -1.41E7 -1.22 7.8799479E7 -1.88E7 -1.64 -2.0204 -0.9891 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C19 compound treatment 9.6849657E7 -4770000.0 -0.41 9.7691319E7 141000.0 0.01 -0.2828 -0.6857 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C20 compound treatment 9.6652991E7 -4970000.0 -0.43 1.0809253E8 1.05E7 0.92 0.3488 0.3428 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C21 compound treatment 1.10117862E8 8490000.0 0.73 1.08873936E8 1.13E7 0.99 1.2195 0.9891 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C22 compound treatment 1.10086884E8 8460000.0 0.73 9.6499821E7 -1050000.0 -0.09 0.4519 0.6133 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C23 compound treatment 1.14045141E8 1.24E7 1.07 1.10382555E8 1.28E7 1.12 1.5528 0.9997 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 C24 compound treatment 1.07080268E8 5460000.0 0.47 1.11258009E8 1.37E7 1.2 1.1816 0.9167 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D01 compound treatment 1.04866019E8 3240000.0 0.28 1.10785763E8 1.32E7 1.16 1.0171 0.8535 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D02 compound treatment 1.04417331E8 2790000.0 0.24 8.7313078E7 -1.02E7 -0.9 -0.4629 -0.4989 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D03 compound treatment 9.6511483E7 -5110000.0 -0.44 9.5186428E7 -2360000.0 -0.21 -0.4585 -0.9404 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D04 compound treatment 1.0133657E8 -287000.0 -0.02 1.01467761E8 3920000.0 0.34 0.2249 0.6544 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D05 compound treatment 1.01167324E8 -456000.0 -0.04 9.7833688E7 283000.0 0.02 -0.0103 -0.2221 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D06 compound treatment 9.9629279E7 -1990000.0 -0.17 9.0613783E7 -6940000.0 -0.61 -0.5511 -0.8732 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D07 compound treatment 9.920119E7 -2420000.0 -0.21 9.3237478E7 -4310000.0 -0.38 -0.4148 -0.9612 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D08 compound treatment 1.01260914E8 -362000.0 -0.03 9.6199811E7 -1350000.0 -0.12 -0.1057 -0.8644 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D09 compound treatment 1.02975666E8 1350000.0 0.12 9.8024041E7 473000.0 0.04 0.1119 0.9027 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D10 compound treatment 9.2278311E7 -9340000.0 -0.81 1.0118959E8 3640000.0 0.32 -0.3455 -0.3982 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D11 mock treatment 1.05767171E8 4140000.0 0.36 9.4741698E7 -2810000.0 -0.25 0.0793 0.1825 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D12 mock treatment 1.02090464E8 467000.0 0.04 9.8526288E7 975000.0 0.09 0.0889 0.9415 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D13 compound treatment 1.052465E8 3620000.0 0.31 1.04709896E8 7160000.0 0.63 0.6643 0.9486 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D14 compound treatment 9.4702635E7 -6920000.0 -0.6 1.0168285E8 4130000.0 0.36 -0.167 -0.239 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D15 mock treatment 1.06079172E8 4460000.0 0.38 9.4230429E7 -3320000.0 -0.29 0.0667 0.1383 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D16 mock treatment 9.8214813E7 -3410000.0 -0.29 9.9680046E7 2130000.0 0.19 -0.0764 -0.2193 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D17 compound treatment 1.00608324E8 -1010000.0 -0.09 9.8810857E7 1260000.0 0.11 0.016 0.1136 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D18 compound treatment 9.8708868E7 -2910000.0 -0.25 1.03399494E8 5850000.0 0.51 0.184 0.3225 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D19 compound treatment 1.11009971E8 9390000.0 0.81 9.7334474E7 -216000.0 -0.02 0.5599 0.6904 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D20 compound treatment 1.08024121E8 6400000.0 0.55 9.6997377E7 -553000.0 -0.05 0.3567 0.6427 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D21 compound treatment 1.13980243E8 1.24E7 1.07 1.09883249E8 1.23E7 1.08 1.5179 1.0 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D22 compound treatment 1.00325468E8 -1300000.0 -0.11 1.05313031E8 7760000.0 0.68 0.4011 0.5826 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D23 compound treatment 1.15055373E8 1.34E7 1.16 1.01614018E8 4060000.0 0.36 1.0718 0.8833 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 D24 compound treatment 1.13470711E8 1.18E7 1.02 1.07427455E8 9880000.0 0.86 1.3348 0.9965 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E01 mock treatment 1.07641903E8 6020000.0 0.52 9.7897338E7 347000.0 0.03 0.389 0.7471 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E02 mock treatment 1.07433015E8 5810000.0 0.5 9.9135637E7 1580000.0 0.14 0.4529 0.8699 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E03 compound treatment 1.05101995E8 3480000.0 0.3 9.9435703E7 1880000.0 0.16 0.3291 0.9601 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E04 compound treatment 9.9299763E7 -2320000.0 -0.2 9.799875E7 448000.0 0.04 -0.1142 -0.5584 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E05 compound treatment 1.0012235E8 -1500000.0 -0.13 1.02512264E8 4960000.0 0.43 0.2154 0.4753 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E06 compound treatment 9.6325663E7 -5300000.0 -0.46 9.4119927E7 -3430000.0 -0.3 -0.5359 -0.9791 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E07 compound treatment 1.01168428E8 -455000.0 -0.04 9.990965E7 2360000.0 0.21 0.1182 0.5625 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E08 compound treatment 9.5193981E7 -6430000.0 -0.56 9.676991E7 -781000.0 -0.07 -0.441 -0.7882 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E09 mock treatment 9.9424611E7 -2200000.0 -0.19 9.6166874E7 -1380000.0 -0.12 -0.2199 -0.9764 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E10 mock treatment 9.5062515E7 -6560000.0 -0.57 9.3067914E7 -4480000.0 -0.39 -0.6781 -0.9839 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E11 compound treatment 1.01763286E8 140000.0 0.01 9.7614028E7 63200.0 0.01 0.0125 0.937 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E12 compound treatment 9.9250039E7 -2370000.0 -0.2 9.4033592E7 -3520000.0 -0.31 -0.3626 -0.9805 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E13 compound treatment 9.8645677E7 -2980000.0 -0.26 9.819055E7 640000.0 0.06 -0.1423 -0.5405 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E14 compound treatment 9.6368946E7 -5250000.0 -0.45 9.6220174E7 -1330000.0 -0.12 -0.4032 -0.8607 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E15 compound treatment 9.98073E7 -1820000.0 -0.16 1.00353595E8 2800000.0 0.25 0.0625 0.2148 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E16 compound treatment 5.0546985E7 -5.11E7 -4.41 5.436382E7 -4.32E7 -3.78 -5.792 -0.997 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E17 mock treatment 1.0649997E8 4880000.0 0.42 1.08001696E8 1.05E7 0.91 0.9446 0.9381 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E18 mock treatment 1.04942063E8 3320000.0 0.29 1.07602358E8 1.01E7 0.88 0.8247 0.8914 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E19 compound treatment 9.5215928E7 -6410000.0 -0.55 9.3537949E7 -4010000.0 -0.35 -0.6396 -0.9759 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E20 compound treatment 1.03667001E8 2040000.0 0.18 1.0361007E8 6060000.0 0.53 0.4998 0.8943 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E21 compound treatment 1.06779629E8 5160000.0 0.45 1.03619988E8 6070000.0 0.53 0.6905 0.9962 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E22 compound treatment 1.04739357E8 3120000.0 0.27 1.03196985E8 5650000.0 0.49 0.5397 0.9592 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E23 compound treatment 1.05158271E8 3540000.0 0.31 1.00101812E8 2550000.0 0.22 0.3738 0.9882 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 E24 compound treatment 1.00884704E8 -738000.0 -0.06 9.8754916E7 1200000.0 0.11 0.0294 0.2388 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F01 mock treatment 1.10125486E8 8500000.0 0.73 1.01436994E8 3890000.0 0.34 0.7598 0.9388 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F02 mock treatment 1.06544355E8 4920000.0 0.43 1.01204488E8 3650000.0 0.32 0.5267 0.9902 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F03 compound treatment 1.06669879E8 5050000.0 0.44 1.01497446E8 3950000.0 0.35 0.5525 0.9934 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F04 compound treatment 9.9450462E7 -2170000.0 -0.19 8.9936559E7 -7610000.0 -0.67 -0.6039 -0.8723 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F05 compound treatment 1.036352E8 2010000.0 0.17 1.00823297E8 3270000.0 0.29 0.3254 0.9713 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F06 compound treatment 9.9501664E7 -2120000.0 -0.18 9.7010338E7 -540000.0 -0.05 -0.163 -0.8614 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F07 compound treatment 9.8724575E7 -2900000.0 -0.25 9.9154717E7 1600000.0 0.14 -0.0778 -0.271 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F08 compound treatment 9.8806878E7 -2820000.0 -0.24 9.5338669E7 -2210000.0 -0.19 -0.3089 -0.9936 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F09 mock treatment 1.00490579E8 -1130000.0 -0.1 9.8918401E7 1370000.0 0.12 0.0155 0.1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F10 mock treatment 9.2912997E7 -8710000.0 -0.75 9.3693932E7 -3860000.0 -0.34 -0.7706 -0.9346 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F11 compound treatment 1.01703938E8 80800.0 0.01 9.8831978E7 1280000.0 0.11 0.0842 0.7497 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F12 compound treatment 1.00144358E8 -1480000.0 -0.13 9.7813044E7 262000.0 0.02 -0.0741 -0.5709 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F13 compound treatment 1.01359811E8 -263000.0 -0.02 9.9668258E7 2120000.0 0.19 0.115 0.6157 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F14 compound treatment 1.0122222E8 -401000.0 -0.03 9.6841676E7 -709000.0 -0.06 -0.0684 -0.962 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F15 compound treatment 1.00677313E8 -946000.0 -0.08 9.895972E7 1410000.0 0.12 0.0294 0.199 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F16 compound treatment 9.4158773E7 -7460000.0 -0.64 8.9218337E7 -8330000.0 -0.73 -0.9715 -0.9981 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F17 mock treatment 1.07718884E8 6100000.0 0.53 1.07692134E8 1.01E7 0.89 0.9999 0.9689 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F18 mock treatment 1.04915545E8 3290000.0 0.28 1.03981728E8 6430000.0 0.56 0.5991 0.95 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F19 compound treatment 1.039129E8 2290000.0 0.2 1.01740472E8 4190000.0 0.37 0.3991 0.958 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F20 compound treatment 1.06408993E8 4790000.0 0.41 1.04560044E8 7010000.0 0.61 0.7261 0.9815 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F21 compound treatment 1.0811538E8 6490000.0 0.56 1.05150199E8 7600000.0 0.67 0.8668 0.9964 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F22 compound treatment 1.06340932E8 4720000.0 0.41 1.05589946E8 8040000.0 0.7 0.7856 0.9663 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F23 compound treatment 1.08464366E8 6840000.0 0.59 1.09331921E8 1.18E7 1.03 1.1469 0.9651 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 F24 compound treatment 1.09741998E8 8120000.0 0.7 1.08960355E8 1.14E7 1.0 1.2019 0.985 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G01 compound treatment 1.06867824E8 5240000.0 0.45 9.6414954E7 -1140000.0 -0.1 0.25 0.5391 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G02 compound treatment 6.878276E7 -3.28E7 -2.84 5.1687989E7 -4.59E7 -4.01 -4.8439 -0.9856 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G03 mock treatment 1.08347569E8 6720000.0 0.58 9.9744037E7 2190000.0 0.19 0.5464 0.8933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G04 mock treatment 1.01584231E8 -38900.0 0.0 9.9729284E7 2180000.0 0.19 0.1324 0.6945 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G05 compound treatment 1.05136376E8 3510000.0 0.3 9.5063869E7 -2490000.0 -0.22 0.0607 0.1625 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G06 compound treatment 1.00543929E8 -1080000.0 -0.09 1.01664472E8 4110000.0 0.36 0.1887 0.5073 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G07 compound treatment 1.0397782E8 2350000.0 0.2 9.6373171E7 -1180000.0 -0.1 0.0709 0.3111 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G08 compound treatment 1.01553274E8 -69800.0 -0.01 9.6544414E7 -1010000.0 -0.09 -0.0665 -0.7538 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G09 compound treatment 9.9209571E7 -2410000.0 -0.21 9.4303192E7 -3250000.0 -0.28 -0.3484 -0.9884 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G10 compound treatment 9.6737701E7 -4890000.0 -0.42 9.4180671E7 -3370000.0 -0.29 -0.5069 -0.9847 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G11 compound treatment 1.02895883E8 1270000.0 0.11 9.7383852E7 -167000.0 -0.01 0.0674 0.6078 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G12 compound treatment 9.9672437E7 -1950000.0 -0.17 9.5017789E7 -2530000.0 -0.22 -0.2759 -0.9908 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G13 compound treatment 9.8669033E7 -2950000.0 -0.26 9.4541418E7 -3010000.0 -0.26 -0.3667 -0.9999 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G14 compound treatment 9.4659611E7 -6960000.0 -0.6 9.8449871E7 899000.0 0.08 -0.3697 -0.6094 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G15 compound treatment 9.8719547E7 -2900000.0 -0.25 9.8482841E7 932000.0 0.08 -0.1197 -0.4537 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G16 compound treatment 9.9547436E7 -2080000.0 -0.18 1.00133685E8 2580000.0 0.23 0.0331 0.1146 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G17 compound treatment 9.5874259E7 -5750000.0 -0.5 9.7873851E7 323000.0 0.03 -0.3311 -0.6658 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G18 compound treatment 1.05465202E8 3840000.0 0.33 1.02156622E8 4610000.0 0.4 0.5197 0.9953 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G19 mock treatment 1.06423696E8 4800000.0 0.41 1.02559951E8 5010000.0 0.44 0.6032 0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G20 mock treatment 1.05001224E8 3380000.0 0.29 1.03225674E8 5670000.0 0.5 0.5575 0.9679 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G21 compound treatment 1.08406482E8 6780000.0 0.59 1.01278253E8 3730000.0 0.33 0.645 0.9618 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G22 compound treatment 1.08381035E8 6760000.0 0.58 1.05695399E8 8140000.0 0.71 0.9168 0.9951 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G23 compound treatment 1.06775968E8 5150000.0 0.45 1.04142202E8 6590000.0 0.58 0.7226 0.9918 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 G24 compound treatment 9.9081817E7 -2540000.0 -0.22 9.8490957E7 940000.0 0.08 -0.097 -0.4139 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H01 compound treatment 1.133086E8 1.17E7 1.01 1.03630872E8 6080000.0 0.53 1.0899 0.9553 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H02 compound treatment 1.05654831E8 4030000.0 0.35 1.0418564E8 6630000.0 0.58 0.6568 0.9701 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H03 mock treatment 1.10190234E8 8570000.0 0.74 1.02531063E8 4980000.0 0.44 0.8314 0.9681 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H04 mock treatment 9.9637267E7 -1990000.0 -0.17 9.5930759E7 -1620000.0 -0.14 -0.2215 -0.9955 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H05 compound treatment 9.8779647E7 -2840000.0 -0.25 9.8866025E7 1320000.0 0.12 -0.0923 -0.3402 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H06 compound treatment 9.9994835E7 -1630000.0 -0.14 8.9453428E7 -8100000.0 -0.71 -0.6005 -0.8312 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H07 compound treatment 1.06183235E8 4560000.0 0.39 1.01165561E8 3610000.0 0.32 0.5022 0.9941 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H08 compound treatment 9.7715644E7 -3910000.0 -0.34 9.5047097E7 -2500000.0 -0.22 -0.3936 -0.9781 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H09 compound treatment 1.03003981E8 1380000.0 0.12 1.01729708E8 4180000.0 0.37 0.3429 0.8915 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H10 compound treatment 9.819364E7 -3430000.0 -0.3 9.2150827E7 -5400000.0 -0.47 -0.5436 -0.9747 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H11 compound treatment 9.9929856E7 -1690000.0 -0.15 9.7175318E7 -375000.0 -0.03 -0.1267 -0.8449 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H12 compound treatment 9.7202039E7 -4420000.0 -0.38 8.8896251E7 -8650000.0 -0.76 -0.8056 -0.9497 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H13 compound treatment 1.00338822E8 -1280000.0 -0.11 1.01645765E8 4090000.0 0.36 0.175 0.4664 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H14 compound treatment 9.2475521E7 -9150000.0 -0.79 8.1395282E7 -1.62E7 -1.41 -1.5585 -0.9622 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H15 compound treatment 1.01007814E8 -615000.0 -0.05 9.772994E7 179000.0 0.02 -0.0265 -0.4781 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H16 compound treatment 1.02855403E8 1230000.0 0.11 9.626793E7 -1280000.0 -0.11 -0.0041 -0.0267 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H17 compound treatment 1.07307228E8 5680000.0 0.49 1.05288787E8 7740000.0 0.68 0.826 0.9875 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H18 compound treatment 1.04351884E8 2730000.0 0.24 9.7925825E7 375000.0 0.03 0.1899 0.7979 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H19 mock treatment 1.09098935E8 7480000.0 0.65 1.03831543E8 6280000.0 0.55 0.8453 0.9968 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H20 mock treatment 1.02916912E8 1290000.0 0.11 1.02285599E8 4730000.0 0.41 0.372 0.8668 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H21 compound treatment 9.1461668E7 -1.02E7 -0.88 9.5030131E7 -2520000.0 -0.22 -0.7766 -0.8581 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H22 compound treatment 9.6045913E7 -5580000.0 -0.48 8.1351349E7 -1.62E7 -1.42 -1.3431 -0.897 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H23 compound treatment 1.14882228E8 1.33E7 1.15 1.08943668E8 1.14E7 1.0 1.5148 0.9976 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 H24 compound treatment 1.13137508E8 1.15E7 0.99 1.04266607E8 6720000.0 0.59 1.1188 0.9685 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I01 compound treatment 1.07394381E8 5770000.0 0.5 1.00018406E8 2470000.0 0.22 0.5052 0.9299 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I02 compound treatment 1.01495923E8 -127000.0 -0.01 9.9033196E7 1480000.0 0.13 0.084 0.6449 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I03 compound treatment 1.0488398E8 3260000.0 0.28 9.6176168E7 -1370000.0 -0.12 0.1141 0.3725 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I04 compound treatment 1.01532665E8 -90400.0 -0.01 9.5494862E7 -2060000.0 -0.18 -0.1328 -0.7371 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I05 mock treatment 1.02712858E8 1090000.0 0.09 9.8386661E7 836000.0 0.07 0.1183 0.9922 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I06 mock treatment 9.8604312E7 -3020000.0 -0.26 9.6205091E7 -1350000.0 -0.12 -0.2676 -0.9355 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I07 compound treatment 1.02422476E8 799000.0 0.07 9.5285257E7 -2270000.0 -0.2 -0.0914 -0.4352 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I08 compound treatment 9.5849631E7 -5770000.0 -0.5 9.0968253E7 -6580000.0 -0.58 -0.76 -0.9974 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I09 compound treatment 9.9165807E7 -2460000.0 -0.21 9.520909E7 -2340000.0 -0.2 -0.295 -0.9998 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I10 compound treatment 9.197708E7 -9650000.0 -0.83 9.072638E7 -6820000.0 -0.6 -1.0114 -0.9867 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I11 compound treatment 9.6269949E7 -5350000.0 -0.46 9.4737895E7 -2810000.0 -0.25 -0.501 -0.9565 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I12 compound treatment 9.1809481E7 -9810000.0 -0.85 9.0928517E7 -6620000.0 -0.58 -1.0092 -0.9828 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I13 compound treatment 9.9293804E7 -2330000.0 -0.2 9.7424049E7 -127000.0 -0.01 -0.1501 -0.745 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I14 compound treatment 9.8054438E7 -3570000.0 -0.31 9.52599E7 -2290000.0 -0.2 -0.3597 -0.9783 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I15 compound treatment 9.9611121E7 -2010000.0 -0.17 9.619151E7 -1360000.0 -0.12 -0.207 -0.9829 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I16 compound treatment 9.395463E7 -7670000.0 -0.66 9.8712854E7 1160000.0 0.1 -0.3964 -0.5916 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I17 compound treatment 9.9225145E7 -2400000.0 -0.21 9.8123883E7 573000.0 0.05 -0.111 -0.5208 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I18 compound treatment 4.053513E7 -6.11E7 -5.28 4.9655104E7 -4.79E7 -4.19 -6.6949 -0.9935 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I19 compound treatment 1.02375776E8 753000.0 0.07 9.8366402E7 816000.0 0.07 0.0964 0.9989 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I20 compound treatment 1.0282586E8 1200000.0 0.1 1.02667287E8 5120000.0 0.45 0.3901 0.8486 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I21 mock treatment 1.06275056E8 4650000.0 0.4 1.02634136E8 5080000.0 0.44 0.5987 0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I22 mock treatment 1.04308777E8 2690000.0 0.23 1.01656909E8 4110000.0 0.36 0.4181 0.9776 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I23 compound treatment 9.9519981E7 -2100000.0 -0.18 1.03371373E8 5820000.0 0.51 0.2318 0.4285 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 I24 compound treatment 1.04997427E8 3370000.0 0.29 1.0740645E8 9860000.0 0.86 0.816 0.8963 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J01 compound treatment 1.13416678E8 1.18E7 1.02 1.06715204E8 9160000.0 0.8 1.2874 0.993 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J02 compound treatment 9.7534317E7 -4090000.0 -0.35 8.5468224E7 -1.21E7 -1.06 -0.9974 -0.8947 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J03 compound treatment 1.06875275E8 5250000.0 0.45 1.01716094E8 4170000.0 0.36 0.5785 0.9941 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J04 compound treatment 9.4294951E7 -7330000.0 -0.63 8.8522329E7 -9030000.0 -0.79 -1.0063 -0.994 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J05 mock treatment 1.04216012E8 2590000.0 0.22 1.00615602E8 3060000.0 0.27 0.348 0.996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J06 mock treatment 9.6270979E7 -5350000.0 -0.46 9.367511E7 -3880000.0 -0.34 -0.5667 -0.9884 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J07 compound treatment 1.0474063E8 3120000.0 0.27 1.01548425E8 4000000.0 0.35 0.4378 0.9916 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J08 compound treatment 5.9650122E7 -4.2E7 -3.63 4.0716037E7 -5.68E7 -4.97 -6.0807 -0.9879 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J09 compound treatment 9.8363031E7 -3260000.0 -0.28 9.6706594E7 -844000.0 -0.07 -0.2513 -0.8634 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J10 compound treatment 9.5885214E7 -5740000.0 -0.5 9.2622298E7 -4930000.0 -0.43 -0.6554 -0.9976 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J11 compound treatment 9.8714658E7 -2910000.0 -0.25 9.7607773E7 57000.0 0.0 -0.1741 -0.6929 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J12 compound treatment 9.1007227E7 -1.06E7 -0.92 8.6173337E7 -1.14E7 -1.0 -1.3524 -0.9992 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J13 compound treatment 1.04421907E8 2800000.0 0.24 9.8403935E7 853000.0 0.07 0.2237 0.8843 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J14 compound treatment 9.161667E7 -1.0E7 -0.86 8.5280478E7 -1.23E7 -1.07 -1.3705 -0.9942 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J15 compound treatment 9.9321465E7 -2300000.0 -0.2 9.908392E7 1530000.0 0.13 -0.0457 -0.1905 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J16 compound treatment 7.4452175E7 -2.72E7 -2.35 7.3013458E7 -2.45E7 -2.15 -3.1779 -0.999 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J17 compound treatment 1.03119128E8 1500000.0 0.13 9.8793132E7 1240000.0 0.11 0.1683 0.9963 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J18 compound treatment 7.7148376E7 -2.45E7 -2.11 7.8821054E7 -1.87E7 -1.64 -2.6539 -0.9921 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J19 compound treatment 1.02805925E8 1180000.0 0.1 1.00595401E8 3040000.0 0.27 0.2607 0.9134 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J20 compound treatment 9.8204315E7 -3420000.0 -0.3 9.3929539E7 -3620000.0 -0.32 -0.4329 -0.9994 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J21 mock treatment 1.05332059E8 3710000.0 0.32 1.057155E8 8160000.0 0.71 0.7318 0.9345 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J22 mock treatment 1.01196326E8 -427000.0 -0.04 9.9713523E7 2160000.0 0.19 0.1078 0.5589 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J23 compound treatment 9.2906732E7 -8720000.0 -0.75 1.07099865E8 9550000.0 0.84 0.0586 0.0521 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 J24 compound treatment 9.477355E7 -6850000.0 -0.59 8.6965378E7 -1.06E7 -0.93 -1.0734 -0.9765 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K01 compound treatment 9.5955604E7 -5670000.0 -0.49 9.0115759E7 -7440000.0 -0.65 -0.8063 -0.9902 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K02 compound treatment 8.5077128E7 -1.65E7 -1.43 9.2583989E7 -4970000.0 -0.43 -1.3179 -0.8823 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K03 compound treatment 6.6973415E7 -3.46E7 -2.99 5.9746192E7 -3.78E7 -3.31 -4.4557 -0.9987 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K04 compound treatment 1.03477762E8 1850000.0 0.16 9.6433998E7 -1120000.0 -0.1 0.0442 0.2353 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K05 compound treatment 1.04008957E8 2390000.0 0.21 9.3092197E7 -4460000.0 -0.39 -0.1302 -0.2951 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K06 compound treatment 1.00358646E8 -1260000.0 -0.11 9.677525E7 -776000.0 -0.07 -0.1252 -0.9738 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K07 mock treatment 9.7656457E7 -3970000.0 -0.34 9.532422E7 -2230000.0 -0.19 -0.3801 -0.9642 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K08 mock treatment 9.5549841E7 -6070000.0 -0.52 9.1456233E7 -6090000.0 -0.53 -0.7481 -1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K09 compound treatment 9.2420153E7 -9200000.0 -0.79 9.0108067E7 -7440000.0 -0.65 -1.0227 -0.9951 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K10 compound treatment 6.2612304E7 -3.9E7 -3.37 6.0018449E7 -3.75E7 -3.28 -4.7052 -0.9999 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K11 compound treatment 9.6208726E7 -5410000.0 -0.47 9.2616414E7 -4930000.0 -0.43 -0.636 -0.9992 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K12 compound treatment 9.49455E7 -6680000.0 -0.58 7.7781508E7 -1.98E7 -1.73 -1.6312 -0.8944 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K13 compound treatment 1.0138089E8 -242000.0 -0.02 9.9060058E7 1510000.0 0.13 0.0786 0.5878 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K14 compound treatment 1.00898451E8 -725000.0 -0.06 9.5379198E7 -2170000.0 -0.19 -0.1786 -0.8928 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K15 mock treatment 1.07098997E8 5480000.0 0.47 9.8403599E7 853000.0 0.07 0.3872 0.8087 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K16 mock treatment 9.5182064E7 -6440000.0 -0.56 9.6394906E7 -1160000.0 -0.1 -0.4649 -0.8222 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K17 compound treatment 1.06168271E8 4550000.0 0.39 9.6507739E7 -1040000.0 -0.09 0.213 0.5286 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K18 compound treatment 1.02537231E8 914000.0 0.08 1.01186062E8 3640000.0 0.32 0.2808 0.8566 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K19 compound treatment 1.02709557E8 1090000.0 0.09 1.0073927E8 3190000.0 0.28 0.2637 0.8956 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K20 compound treatment 1.04547087E8 2920000.0 0.25 9.6749506E7 -801000.0 -0.07 0.129 0.4921 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K21 compound treatment 9.887136E7 -2750000.0 -0.24 1.02378886E8 4830000.0 0.42 0.1307 0.2696 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K22 compound treatment 1.06077341E8 4450000.0 0.38 1.04246927E8 6700000.0 0.59 0.6864 0.9792 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K23 mock treatment 1.06490953E8 4870000.0 0.42 1.0353505E8 5980000.0 0.52 0.6676 0.9941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 K24 mock treatment 1.04313747E8 2690000.0 0.23 1.00035205E8 2480000.0 0.22 0.3181 0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L01 compound treatment 9.2058446E7 -9560000.0 -0.83 1.02971863E8 5420000.0 0.47 -0.2487 -0.261 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L02 compound treatment 9.3297302E7 -8330000.0 -0.72 9.5899597E7 -1650000.0 -0.14 -0.6107 -0.8326 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L03 compound treatment 9.9278322E7 -2340000.0 -0.2 9.5829065E7 -1720000.0 -0.15 -0.2498 -0.9894 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L04 compound treatment 9.550802E7 -6120000.0 -0.53 8.8300164E7 -9250000.0 -0.81 -0.9459 -0.9786 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L05 compound treatment 1.07987448E8 6360000.0 0.55 9.6545941E7 -1000000.0 -0.09 0.3265 0.5865 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L06 compound treatment 9.3240339E7 -8380000.0 -0.72 8.1718495E7 -1.58E7 -1.39 -1.4917 -0.9542 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L07 mock treatment 1.04321609E8 2700000.0 0.23 9.5924148E7 -1630000.0 -0.14 0.0641 0.2349 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L08 mock treatment 9.7420438E7 -4200000.0 -0.36 9.4109052E7 -3440000.0 -0.3 -0.4697 -0.9957 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L09 compound treatment 9.5546976E7 -6080000.0 -0.52 9.8949747E7 1400000.0 0.12 -0.2845 -0.528 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L10 compound treatment 9.6275133E7 -5350000.0 -0.46 8.0804633E7 -1.67E7 -1.47 -1.3629 -0.887 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L11 compound treatment 1.04525048E8 2900000.0 0.25 9.6206943E7 -1340000.0 -0.12 0.0941 0.3398 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L12 compound treatment 1.01178772E8 -444000.0 -0.04 9.4955062E7 -2600000.0 -0.23 -0.1878 -0.815 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L13 compound treatment 1.00911862E8 -711000.0 -0.06 9.5240882E7 -2310000.0 -0.2 -0.1864 -0.8821 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L14 compound treatment 8.8117011E7 -1.35E7 -1.17 7.7967305E7 -1.96E7 -1.71 -2.0368 -0.9824 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L15 mock treatment 1.06432011E8 4810000.0 0.42 7.992323E7 -1.76E7 -1.54 -0.7972 -0.499 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L16 mock treatment 1.00175012E8 -1450000.0 -0.13 8.3630098E7 -1.39E7 -1.22 -0.9499 -0.7756 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L17 compound treatment 9.8203731E7 -3420000.0 -0.3 1.00215803E8 2660000.0 0.23 -0.0439 -0.1167 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L18 compound treatment 8.992553E7 -1.17E7 -1.01 8.7140412E7 -1.04E7 -0.91 -1.3587 -0.9987 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L19 compound treatment 1.05377606E8 3750000.0 0.32 1.00577926E8 3030000.0 0.26 0.4166 0.995 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L20 compound treatment 8.4157699E7 -1.75E7 -1.51 7.1391672E7 -2.62E7 -2.29 -2.6855 -0.9795 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L21 compound treatment 1.11392089E8 9770000.0 0.84 1.07445778E8 9890000.0 0.87 1.209 0.9999 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L22 compound treatment 8.5952205E7 -1.57E7 -1.35 7.8703341E7 -1.88E7 -1.65 -2.1235 -0.9952 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L23 mock treatment 1.06488495E8 4870000.0 0.42 1.06192874E8 8640000.0 0.76 0.832 0.9615 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 L24 mock treatment 1.0939313E8 7770000.0 0.67 9.7145417E7 -405000.0 -0.04 0.4495 0.6688 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M01 compound treatment 9.6087677E7 -5540000.0 -0.48 9.9963075E7 2410000.0 0.21 -0.1888 -0.3612 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M02 compound treatment 1.01877785E8 255000.0 0.02 1.00274476E8 2720000.0 0.24 0.1841 0.7691 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M03 compound treatment 1.08737288E8 7110000.0 0.61 9.3923584E7 -3630000.0 -0.32 0.21 0.3037 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M04 compound treatment 1.05136178E8 3510000.0 0.3 9.7232774E7 -318000.0 -0.03 0.1949 0.6396 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M05 compound treatment 8.0835114E7 -2.08E7 -1.8 9.8560599E7 1010000.0 0.09 -1.2071 -0.6715 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M06 compound treatment 8.6657756E7 -1.5E7 -1.29 8.8394783E7 -9160000.0 -0.8 -1.4806 -0.9736 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M07 compound treatment 9.9575404E7 -2050000.0 -0.18 9.7285066E7 -266000.0 -0.02 -0.1415 -0.7933 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M08 compound treatment 9.0924807E7 -1.07E7 -0.92 9.4108607E7 -3440000.0 -0.3 -0.8664 -0.8915 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M09 mock treatment 1.01205111E8 -418000.0 -0.04 9.3515627E7 -4040000.0 -0.35 -0.2752 -0.7754 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M10 mock treatment 9.9794208E7 -1830000.0 -0.16 8.4710049E7 -1.28E7 -1.12 -0.9063 -0.7986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M11 compound treatment 8.4660449E7 -1.7E7 -1.47 9.1689335E7 -5860000.0 -0.51 -1.3987 -0.9011 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M12 compound treatment 7.9350862E7 -2.23E7 -1.92 8.3419933E7 -1.41E7 -1.24 -2.2347 -0.9772 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M13 mock treatment 9.7267733E7 -4360000.0 -0.38 8.7344117E7 -1.02E7 -0.89 -0.8976 -0.9261 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M14 mock treatment 9.1349717E7 -1.03E7 -0.89 9.1578719E7 -5970000.0 -0.52 -0.997 -0.9681 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M15 compound treatment 9.7352313E7 -4270000.0 -0.37 9.6791801E7 -759000.0 -0.07 -0.3078 -0.8212 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M16 compound treatment 8.9899484E7 -1.17E7 -1.01 8.191118E7 -1.56E7 -1.37 -1.6839 -0.989 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M17 compound treatment 9.3737215E7 -7890000.0 -0.68 1.00535772E8 2980000.0 0.26 -0.2969 -0.407 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M18 compound treatment 1.00359441E8 -1260000.0 -0.11 9.6372155E7 -1180000.0 -0.1 -0.1501 -0.9996 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M19 mock treatment 1.04173874E8 2550000.0 0.22 9.3408795E7 -4140000.0 -0.36 -0.1005 -0.237 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M20 compound treatment 9.2323606E7 -9300000.0 -0.8 9.4717667E7 -2830000.0 -0.25 -0.7433 -0.8842 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M21 mock treatment 9.5903788E7 -5720000.0 -0.49 9.0338625E7 -7210000.0 -0.63 -0.7956 -0.9926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M22 compound treatment 1.00193709E8 -1430000.0 -0.12 8.8050776E7 -9500000.0 -0.83 -0.6752 -0.8033 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M23 mock treatment 9.6519219E7 -5100000.0 -0.44 9.5390984E7 -2160000.0 -0.19 -0.4454 -0.9285 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 M24 compound treatment 1.0078772E8 -835000.0 -0.07 9.9306231E7 1760000.0 0.15 0.0576 0.3394 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N01 compound treatment 1.04166786E8 2540000.0 0.22 9.9522348E7 1970000.0 0.17 0.2774 0.9928 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N02 compound treatment 8.2997523E7 -1.86E7 -1.61 2.9850589E7 -6.77E7 -5.92 -5.3271 -0.8677 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N03 compound treatment 1.13747218E8 1.21E7 1.05 9.266172E7 -4890000.0 -0.43 0.4379 0.3871 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N04 compound treatment 1.06062337E8 4440000.0 0.38 9.8967453E7 1420000.0 0.12 0.3588 0.8904 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N05 compound treatment 7.8750731E7 -2.29E7 -1.98 9.8516573E7 966000.0 0.08 -1.3372 -0.6762 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N06 compound treatment 8.2798932E7 -1.88E7 -1.63 8.6491213E7 -1.11E7 -0.97 -1.8341 -0.9693 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N07 compound treatment 1.05221115E8 3600000.0 0.31 9.720744E7 -343000.0 -0.03 0.1985 0.6358 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N08 compound treatment 9.1546461E7 -1.01E7 -0.87 8.9424905E7 -8130000.0 -0.71 -1.1183 -0.995 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N09 mock treatment 9.7601636E7 -4020000.0 -0.35 8.755308E7 -1.0E7 -0.87 -0.8643 -0.9181 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N10 mock treatment 9.9339478E7 -2280000.0 -0.2 9.2258939E7 -5290000.0 -0.46 -0.467 -0.9276 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N11 compound treatment 9.5409423E7 -6210000.0 -0.54 7.6954381E7 -2.06E7 -1.8 -1.6541 -0.8795 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N12 compound treatment 7.7068057E7 -2.46E7 -2.12 7.3467689E7 -2.41E7 -2.11 -2.9901 -1.0 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N13 mock treatment 1.0134819E8 -275000.0 -0.02 9.6206775E7 -1340000.0 -0.12 -0.1 -0.833 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N14 mock treatment 9.7914663E7 -3710000.0 -0.32 9.2583258E7 -4970000.0 -0.43 -0.5339 -0.9887 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N15 compound treatment 9.3563216E7 -8060000.0 -0.7 8.9594364E7 -7960000.0 -0.7 -0.9846 -1.0 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N16 compound treatment 1.00283518E8 -1340000.0 -0.12 9.5222616E7 -2330000.0 -0.2 -0.2259 -0.964 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N17 compound treatment 1.02023418E8 400000.0 0.03 9.9067897E7 1520000.0 0.13 0.1183 0.8625 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N18 compound treatment 8.8507103E7 -1.31E7 -1.13 7.7820896E7 -1.97E7 -1.73 -2.022 -0.9791 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N19 compound treatment 9.1231835E7 -1.04E7 -0.9 1.02242314E8 4690000.0 0.41 -0.3443 -0.3489 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N20 compound treatment 8.561171E7 -1.6E7 -1.38 7.9767397E7 -1.78E7 -1.56 -2.0784 -0.9983 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N21 compound treatment 8.8949278E7 -1.27E7 -1.09 7.4414867E7 -2.31E7 -2.02 -2.2058 -0.9583 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N22 compound treatment 8.8712708E7 -1.29E7 -1.12 8.0443129E7 -1.71E7 -1.5 -1.8472 -0.9895 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N23 compound treatment 1.02478743E8 856000.0 0.07 1.04807635E8 7260000.0 0.64 0.5013 0.7841 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 N24 compound treatment 6.7204405E7 -3.44E7 -2.97 5.9866012E7 -3.77E7 -3.3 -4.4342 -0.9987 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O01 mock treatment 1.10162035E8 8540000.0 0.74 1.02030978E8 4480000.0 0.39 0.7988 0.9563 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O02 compound treatment 9.6365046E7 -5260000.0 -0.45 8.5911407E7 -1.16E7 -1.02 -1.0414 -0.9338 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O03 mock treatment 8.3817197E7 -1.78E7 -1.54 1.01093181E8 3540000.0 0.31 -0.8683 -0.5534 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O04 mock treatment 8.6088392E7 -1.55E7 -1.34 9.4874692E7 -2680000.0 -0.23 -1.1144 -0.8182 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O05 mock treatment 1.07828366E8 6210000.0 0.54 9.7657702E7 107000.0 0.01 0.3856 0.7193 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O06 mock treatment 9.9939255E7 -1680000.0 -0.15 9.6359758E7 -1190000.0 -0.1 -0.1765 -0.9867 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O07 mock treatment 1.00731303E8 -892000.0 -0.08 9.604696E7 -1500000.0 -0.13 -0.1475 -0.9674 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O08 mock treatment 9.9591234E7 -2030000.0 -0.18 9.2165346E7 -5390000.0 -0.47 -0.4574 -0.9094 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O09 mock treatment 9.5688141E7 -5930000.0 -0.51 9.2547275E7 -5000000.0 -0.44 -0.6721 -0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O10 mock treatment 9.2350163E7 -9270000.0 -0.8 9.0311583E7 -7240000.0 -0.63 -1.0143 -0.9933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O11 mock treatment 9.8364162E7 -3260000.0 -0.28 9.3730001E7 -3820000.0 -0.33 -0.4355 -0.9963 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O12 mock treatment 9.3612627E7 -8010000.0 -0.69 8.6172405E7 -1.14E7 -1.0 -1.1934 -0.9842 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O13 mock treatment 9.8714258E7 -2910000.0 -0.25 8.8311097E7 -9240000.0 -0.81 -0.7494 -0.8851 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O14 mock treatment 9.7407929E7 -4220000.0 -0.36 8.0487668E7 -1.71E7 -1.49 -1.3134 -0.8545 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O15 mock treatment 1.01445277E8 -178000.0 -0.02 9.5944833E7 -1610000.0 -0.14 -0.1102 -0.7797 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O16 mock treatment 9.7383826E7 -4240000.0 -0.37 9.0067458E7 -7480000.0 -0.65 -0.722 -0.9623 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O17 mock treatment 1.05061458E8 3440000.0 0.3 9.9021305E7 1470000.0 0.13 0.301 0.93 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O18 mock treatment 9.8356917E7 -3270000.0 -0.28 9.7389979E7 -161000.0 -0.01 -0.2094 -0.7415 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O19 mock treatment 1.05686923E8 4060000.0 0.35 1.02683081E8 5130000.0 0.45 0.5658 0.9926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O20 mock treatment 1.03947016E8 2320000.0 0.2 9.9911499E7 2360000.0 0.21 0.288 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O21 mock treatment 1.06145888E8 4520000.0 0.39 1.04381712E8 6830000.0 0.6 0.699 0.9787 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O22 mock treatment 1.05670202E8 4050000.0 0.35 1.01339656E8 3790000.0 0.33 0.4816 0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O23 mock treatment 1.02068439E8 445000.0 0.04 1.0370585E8 6160000.0 0.54 0.4081 0.7557 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 O24 mock treatment 1.0624773E8 4620000.0 0.4 1.02549468E8 5000000.0 0.44 0.5918 0.999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P01 compound treatment 1.10129313E8 8510000.0 0.73 9.4946693E7 -2600000.0 -0.23 0.3584 0.4659 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P02 compound treatment 9.7814086E7 -3810000.0 -0.33 8.9750067E7 -7800000.0 -0.68 -0.7154 -0.944 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P03 compound treatment 8.6076506E7 -1.55E7 -1.34 9.590288E7 -1650000.0 -0.14 -1.0515 -0.7786 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P04 compound treatment 8.6573928E7 -1.5E7 -1.3 8.7209814E7 -1.03E7 -0.91 -1.5591 -0.9843 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P05 compound treatment 1.0177311E8 150000.0 0.01 9.4744819E7 -2810000.0 -0.25 -0.1645 -0.6689 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P06 compound treatment 1.02280337E8 657000.0 0.06 9.519383E7 -2360000.0 -0.21 -0.1057 -0.4941 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P07 compound treatment 1.04186973E8 2560000.0 0.22 9.6591916E7 -959000.0 -0.08 0.0972 0.4106 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P08 compound treatment 9.7748443E7 -3870000.0 -0.33 8.1455058E7 -1.61E7 -1.41 -1.2327 -0.8514 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P09 compound treatment 1.02023934E8 401000.0 0.03 9.2517219E7 -5030000.0 -0.44 -0.287 -0.6495 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P10 compound treatment 9.6958935E7 -4660000.0 -0.4 7.919805E7 -1.84E7 -1.61 -1.4206 -0.8579 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P11 mock treatment 1.03521366E8 1900000.0 0.16 9.3525951E7 -4020000.0 -0.35 -0.1331 -0.3427 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P12 mock treatment 9.8079227E7 -3540000.0 -0.31 8.9957472E7 -7590000.0 -0.66 -0.6863 -0.9381 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P13 compound treatment 9.4857486E7 -6770000.0 -0.58 7.9465451E7 -1.81E7 -1.58 -1.5324 -0.9082 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P14 compound treatment 8.6307725E7 -1.53E7 -1.32 5.2145258E7 -4.54E7 -3.97 -3.7453 -0.8942 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P15 compound treatment 1.04055463E8 2430000.0 0.21 9.4697539E7 -2850000.0 -0.25 -0.028 -0.0859 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P16 compound treatment 9.3992447E7 -7630000.0 -0.66 8.5230165E7 -1.23E7 -1.08 -1.2285 -0.9721 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P17 compound treatment 1.03720525E8 2100000.0 0.18 9.9885971E7 2340000.0 0.2 0.2726 0.9982 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P18 compound treatment 9.0838758E7 -1.08E7 -0.93 7.676562E7 -2.08E7 -1.82 -1.9449 -0.9517 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P19 compound treatment 1.09379124E8 7760000.0 0.67 1.00127548E8 2580000.0 0.23 0.6332 0.8957 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P20 compound treatment 8.9729883E7 -1.19E7 -1.03 7.4798259E7 -2.28E7 -1.99 -2.1344 -0.9526 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P21 compound treatment 1.08074529E8 6450000.0 0.56 1.04867069E8 7320000.0 0.64 0.8468 0.9976 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P22 compound treatment 9.3956845E7 -7670000.0 -0.66 8.7909677E7 -9640000.0 -0.84 -1.0648 -0.9928 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P23 compound treatment 1.08067686E8 6440000.0 0.56 1.05288761E8 7740000.0 0.68 0.8725 0.9953 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.2130 P24 compound treatment 1.00550439E8 -1070000.0 -0.09 8.9413589E7 -8140000.0 -0.71 -0.5691 -0.7924 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A01 mock treatment 1.14318398E8 2.02E7 1.74 9.1354564E7 -4750000.0 -0.42 0.9375 0.5236 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A02 mock treatment 9.8298908E7 4140000.0 0.36 1.04972966E8 8870000.0 0.78 0.8019 0.9382 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A03 mock treatment 9.2698732E7 -1460000.0 -0.13 1.01131101E8 5030000.0 0.44 0.2221 0.4855 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A04 mock treatment 9.6224168E7 2070000.0 0.18 1.04199766E8 8100000.0 0.71 0.6274 0.8586 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A05 mock treatment 9.4424967E7 270000.0 0.02 8.8389684E7 -7710000.0 -0.68 -0.4609 -0.6823 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A06 mock treatment 8.8942269E7 -5210000.0 -0.45 1.02628291E8 6520000.0 0.57 0.0854 0.1174 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A07 mock treatment 9.8039979E7 3880000.0 0.34 1.02217024E8 6110000.0 0.53 0.6156 0.9747 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A08 mock treatment 9.4113367E7 -41700.0 0.0 9.9073938E7 2970000.0 0.26 0.1812 0.6972 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A09 mock treatment 9.6225054E7 2070000.0 0.18 8.4064818E7 -1.2E7 -1.05 -0.6186 -0.5789 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A10 mock treatment 8.4227738E7 -9930000.0 -0.86 9.5348327E7 -756000.0 -0.07 -0.6531 -0.7594 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A11 mock treatment 9.3986201E7 -169000.0 -0.01 9.1261549E7 -4840000.0 -0.42 -0.31 -0.731 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A12 mock treatment 8.8423055E7 -5730000.0 -0.5 8.88191E7 -7290000.0 -0.64 -0.8009 -0.9922 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A13 mock treatment 8.8189961E7 -5970000.0 -0.52 7.9488078E7 -1.66E7 -1.45 -1.3926 -0.9027 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A14 mock treatment 8.2458502E7 -1.17E7 -1.01 9.0647676E7 -5460000.0 -0.48 -1.052 -0.9415 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A15 mock treatment 9.3523859E7 -631000.0 -0.05 9.3735506E7 -2370000.0 -0.21 -0.1851 -0.8637 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A16 mock treatment 9.1310572E7 -2840000.0 -0.25 9.4631776E7 -1470000.0 -0.13 -0.2649 -0.9546 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A17 mock treatment 9.4295944E7 141000.0 0.01 8.7153082E7 -8950000.0 -0.78 -0.5453 -0.696 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A18 mock treatment 8.4212523E7 -9940000.0 -0.86 9.9465336E7 3360000.0 0.29 -0.3992 -0.4398 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A19 mock treatment 9.2491382E7 -1660000.0 -0.14 1.02039451E8 5940000.0 0.52 0.2657 0.493 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A20 mock treatment 9.6361229E7 2210000.0 0.19 1.02511204E8 6410000.0 0.56 0.5312 0.897 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A21 mock treatment 8.7446973E7 -6710000.0 -0.58 9.2724346E7 -3380000.0 -0.3 -0.6189 -0.9513 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A22 mock treatment 9.8809837E7 4650000.0 0.4 1.05692836E8 9590000.0 0.84 0.8777 0.9432 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A23 mock treatment 1.04135862E8 9980000.0 0.86 1.0557511E8 9470000.0 0.83 1.1957 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base A24 mock treatment 9.9604009E7 5450000.0 0.47 1.05283001E8 9180000.0 0.8 0.9008 0.9676 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B01 mock treatment 9.5717995E7 1560000.0 0.13 1.04729708E8 8630000.0 0.75 0.6292 0.8205 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B02 mock treatment 9.5768341E7 1610000.0 0.14 1.05415574E8 9310000.0 0.81 0.6748 0.8162 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B03 mock treatment 1.00637054E8 6480000.0 0.56 1.00338651E8 4230000.0 0.37 0.6579 0.9799 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B04 mock treatment 9.4152693E7 -2410.0 0.0 8.7484699E7 -8620000.0 -0.75 -0.5336 -0.7073 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B05 mock treatment 8.7671463E7 -6480000.0 -0.56 9.6527448E7 423000.0 0.04 -0.3698 -0.6589 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B06 mock treatment 9.2484342E7 -1670000.0 -0.14 9.9113616E7 3010000.0 0.26 0.0842 0.2803 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B07 mock treatment 9.6674904E7 2520000.0 0.22 1.00417266E8 4310000.0 0.38 0.4208 0.9658 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B08 mock treatment 9.0814065E7 -3340000.0 -0.29 8.889586E7 -7210000.0 -0.63 -0.6501 -0.9372 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B09 mock treatment 8.4398752E7 -9760000.0 -0.84 9.0489601E7 -5610000.0 -0.49 -0.9433 -0.967 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B10 mock treatment 8.6635913E7 -7520000.0 -0.65 8.9869744E7 -6230000.0 -0.55 -0.845 -0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B11 mock treatment 8.8315859E7 -5840000.0 -0.5 9.0957827E7 -5150000.0 -0.45 -0.6751 -0.9984 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B12 mock treatment 8.0399669E7 -1.38E7 -1.19 7.5947246E7 -2.02E7 -1.76 -2.0875 -0.9815 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B13 mock treatment 8.1137567E7 -1.3E7 -1.12 8.9315362E7 -6790000.0 -0.59 -1.2152 -0.9556 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B14 mock treatment 8.3849188E7 -1.03E7 -0.89 8.8243526E7 -7860000.0 -0.69 -1.1159 -0.9919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B15 mock treatment 9.1972666E7 -2180000.0 -0.19 8.9427232E7 -6680000.0 -0.58 -0.5465 -0.89 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B16 mock treatment 7.8833742E7 -1.53E7 -1.32 8.273225E7 -1.34E7 -1.17 -1.7633 -0.9981 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B17 mock treatment 9.1857383E7 -2300000.0 -0.2 9.7173694E7 1070000.0 0.09 -0.0741 -0.3379 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B18 mock treatment 8.9872055E7 -4280000.0 -0.37 9.803431E7 1930000.0 0.17 -0.1421 -0.3495 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B19 mock treatment 9.5134291E7 979000.0 0.08 9.9984568E7 3880000.0 0.34 0.2999 0.857 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B20 mock treatment 8.320104E7 -1.1E7 -0.95 8.9023212E7 -7080000.0 -0.62 -1.1072 -0.979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B21 mock treatment 9.6045772E7 1890000.0 0.16 1.0373979E8 7640000.0 0.67 0.588 0.8548 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B22 mock treatment 9.2764064E7 -1390000.0 -0.12 1.06168846E8 1.01E7 0.88 0.5379 0.6051 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B23 mock treatment 1.06027229E8 1.19E7 1.03 1.07935155E8 1.18E7 1.04 1.4572 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base B24 mock treatment 9.4199818E7 44700.0 0.0 9.9354248E7 3250000.0 0.28 0.2039 0.7166 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C01 mock treatment 1.14215882E8 2.01E7 1.73 9.7488386E7 1380000.0 0.12 1.3109 0.7547 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C02 mock treatment 9.943965E7 5280000.0 0.46 1.08886449E8 1.28E7 1.12 1.1138 0.9218 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C03 mock treatment 9.684008E7 2680000.0 0.23 9.855706E7 2450000.0 0.21 0.3158 0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C04 mock treatment 9.7150309E7 3000000.0 0.26 9.8128519E7 2020000.0 0.18 0.3082 0.9829 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C05 mock treatment 8.9550186E7 -4600000.0 -0.4 8.4110316E7 -1.2E7 -1.05 -1.0235 -0.9118 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C06 mock treatment 9.5663868E7 1510000.0 0.13 9.853677E7 2430000.0 0.21 0.2427 0.9723 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C07 mock treatment 9.5426659E7 1270000.0 0.11 9.3485524E7 -2620000.0 -0.23 -0.0844 -0.3321 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C08 mock treatment 8.89196E7 -5240000.0 -0.45 8.9346951E7 -6760000.0 -0.59 -0.7379 -0.9912 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C09 mock treatment 9.0224026E7 -3930000.0 -0.34 8.0033767E7 -1.61E7 -1.41 -1.2346 -0.8533 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C10 mock treatment 8.3376549E7 -1.08E7 -0.93 8.6605021E7 -9500000.0 -0.83 -1.2461 -0.9984 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C11 mock treatment 8.8248549E7 -5910000.0 -0.51 8.7779761E7 -8320000.0 -0.73 -0.8759 -0.9848 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C12 mock treatment 8.6986641E7 -7170000.0 -0.62 8.3787643E7 -1.23E7 -1.08 -1.2 -0.9654 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C13 mock treatment 8.3211762E7 -1.09E7 -0.95 8.0326588E7 -1.58E7 -1.38 -1.6447 -0.9829 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C14 mock treatment 9.0028117E7 -4130000.0 -0.36 9.0550613E7 -5550000.0 -0.49 -0.5957 -0.9884 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C15 mock treatment 9.2147371E7 -2010000.0 -0.17 9.4903726E7 -1200000.0 -0.11 -0.1969 -0.9712 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C16 mock treatment 8.7156058E7 -7000000.0 -0.6 9.1112438E7 -4990000.0 -0.44 -0.7364 -0.9873 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C17 mock treatment 9.2063902E7 -2090000.0 -0.18 8.5677508E7 -1.04E7 -0.91 -0.773 -0.8309 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C18 mock treatment 9.4058628E7 -96500.0 -0.01 9.9074978E7 2970000.0 0.26 0.1779 0.6841 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C19 mock treatment 9.949493E7 5340000.0 0.46 9.9059393E7 2960000.0 0.26 0.509 0.9626 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C20 mock treatment 9.4920207E7 765000.0 0.07 9.9730244E7 3630000.0 0.32 0.2711 0.8364 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C21 mock treatment 1.029029E8 8750000.0 0.76 9.2303069E7 -3800000.0 -0.33 0.299 0.3622 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C22 mock treatment 9.9171275E7 5020000.0 0.43 1.03896916E8 7790000.0 0.68 0.7886 0.976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C23 mock treatment 1.04386871E8 1.02E7 0.88 1.06208229E8 1.01E7 0.88 1.2502 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base C24 mock treatment 9.7711131E7 3560000.0 0.31 1.00076364E8 3970000.0 0.35 0.463 0.9981 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D01 mock treatment 1.03115482E8 8960000.0 0.77 9.8305438E7 2200000.0 0.19 0.6835 0.857 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D02 mock treatment 9.6478831E7 2320000.0 0.2 1.05713486E8 9610000.0 0.84 0.7366 0.8519 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D03 mock treatment 9.8935001E7 4780000.0 0.41 1.01736142E8 5630000.0 0.49 0.6405 0.9961 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D04 mock treatment 9.6096651E7 1940000.0 0.17 9.9497422E7 3390000.0 0.3 0.3286 0.9634 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D05 mock treatment 9.9472555E7 5320000.0 0.46 8.5894934E7 -1.02E7 -0.89 -0.307 -0.3056 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D06 mock treatment 8.5287978E7 -8870000.0 -0.77 9.6263843E7 160000.0 0.01 -0.5317 -0.6941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D07 mock treatment 9.6486073E7 2330000.0 0.2 9.8200089E7 2100000.0 0.18 0.2721 0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D08 mock treatment 9.0867219E7 -3290000.0 -0.28 8.8925484E7 -7180000.0 -0.63 -0.6451 -0.9356 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D09 mock treatment 9.2446646E7 -1710000.0 -0.15 8.3244064E7 -1.29E7 -1.13 -0.9002 -0.793 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D10 mock treatment 8.1301292E7 -1.29E7 -1.11 8.6490548E7 -9610000.0 -0.84 -1.38 -0.9906 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D11 mock treatment 9.0312602E7 -3840000.0 -0.33 9.3211662E7 -2890000.0 -0.25 -0.4137 -0.9911 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D12 mock treatment 8.6794536E7 -7360000.0 -0.64 8.3762509E7 -1.23E7 -1.08 -1.2133 -0.9681 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D13 mock treatment 8.3165834E7 -1.1E7 -0.95 8.3860292E7 -1.22E7 -1.07 -1.4289 -0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D14 mock treatment 8.3664783E7 -1.05E7 -0.91 8.982979E7 -6270000.0 -0.55 -1.029 -0.9712 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D15 mock treatment 9.4492609E7 338000.0 0.03 9.5288025E7 -816000.0 -0.07 -0.0299 -0.3875 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D16 mock treatment 8.8610123E7 -5540000.0 -0.48 9.4445439E7 -1660000.0 -0.15 -0.4413 -0.8818 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D17 mock treatment 8.5207498E7 -8950000.0 -0.77 8.6300836E7 -9800000.0 -0.86 -1.1531 -0.9986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D18 mock treatment 9.432479E7 170000.0 0.01 9.6766851E7 663000.0 0.06 0.0514 0.8588 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D19 mock treatment 1.0008744E8 5930000.0 0.51 1.02140919E8 6040000.0 0.53 0.7359 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D20 mock treatment 9.8829527E7 4670000.0 0.4 1.00885847E8 4780000.0 0.42 0.5814 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D21 mock treatment 1.01992387E8 7840000.0 0.68 9.4306619E7 -1800000.0 -0.16 0.3674 0.5287 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D22 mock treatment 9.2073094E7 -2080000.0 -0.18 1.02830953E8 6730000.0 0.59 0.2891 0.4697 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D23 mock treatment 1.09674077E8 1.55E7 1.34 1.08795525E8 1.27E7 1.11 1.7332 0.9956 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base D24 mock treatment 1.08433192E8 1.43E7 1.23 1.08462017E8 1.24E7 1.08 1.6368 0.9979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E01 mock treatment 1.10786193E8 1.66E7 1.44 1.06838089E8 1.07E7 0.94 1.68 0.9788 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E02 mock treatment 1.00657019E8 6500000.0 0.56 1.02563528E8 6460000.0 0.57 0.7968 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E03 mock treatment 9.9080387E7 4930000.0 0.43 9.9652952E7 3550000.0 0.31 0.5204 0.988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E04 mock treatment 9.7060132E7 2910000.0 0.25 9.393084E7 -2170000.0 -0.19 0.0429 0.1363 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E05 mock treatment 9.3160522E7 -995000.0 -0.09 9.6498994E7 395000.0 0.03 -0.0363 -0.3922 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E06 mock treatment 9.0791648E7 -3360000.0 -0.29 9.4182501E7 -1920000.0 -0.17 -0.3243 -0.9662 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E07 mock treatment 9.5296704E7 1140000.0 0.1 9.266417E7 -3440000.0 -0.3 -0.1432 -0.4519 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E08 mock treatment 8.5635379E7 -8520000.0 -0.74 8.8148694E7 -7960000.0 -0.7 -1.0127 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E09 mock treatment 8.6094106E7 -8060000.0 -0.7 8.7581057E7 -8520000.0 -0.75 -1.0198 -0.9994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E10 mock treatment 8.3094632E7 -1.11E7 -0.96 8.5793828E7 -1.03E7 -0.9 -1.3136 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E11 mock treatment 8.5642474E7 -8510000.0 -0.74 8.6083431E7 -1.0E7 -0.88 -1.14 -0.9962 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E12 mock treatment 8.3085534E7 -1.11E7 -0.96 8.4043195E7 -1.21E7 -1.06 -1.4225 -0.9988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E13 mock treatment 8.6769363E7 -7390000.0 -0.64 8.9470753E7 -6630000.0 -0.58 -0.8616 -0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E14 mock treatment 8.4381876E7 -9770000.0 -0.84 8.4567778E7 -1.15E7 -1.01 -1.3108 -0.996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E15 mock treatment 9.0033598E7 -4120000.0 -0.36 9.2335697E7 -3770000.0 -0.33 -0.4849 -0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E16 mock treatment 9.051004E7 -3650000.0 -0.31 9.1993047E7 -4110000.0 -0.36 -0.477 -0.9978 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E17 mock treatment 1.01173361E8 7020000.0 0.61 9.9264099E7 3160000.0 0.28 0.6242 0.9368 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E18 mock treatment 1.01458798E8 7300000.0 0.63 1.01970303E8 5870000.0 0.51 0.8091 0.9948 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E19 mock treatment 9.8767424E7 4610000.0 0.4 9.8390925E7 2290000.0 0.2 0.4232 0.9493 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E20 mock treatment 9.3122898E7 -1030000.0 -0.09 9.9771693E7 3670000.0 0.32 0.1639 0.4921 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E21 mock treatment 1.0133681E8 7180000.0 0.62 1.00531623E8 4430000.0 0.39 0.7126 0.9743 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E22 mock treatment 9.8334372E7 4180000.0 0.36 1.01248688E8 5140000.0 0.45 0.5736 0.994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E23 mock treatment 1.07153285E8 1.3E7 1.12 1.02452504E8 6350000.0 0.56 1.1867 0.9474 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base E24 mock treatment 1.03237708E8 9080000.0 0.78 1.03125688E8 7020000.0 0.61 0.9892 0.9927 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F01 mock treatment 8.8842628E7 -5310000.0 -0.46 1.01947493E8 5840000.0 0.51 0.0371 0.0541 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F02 mock treatment 9.908484E7 4930000.0 0.43 1.03802733E8 7700000.0 0.67 0.7775 0.9755 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F03 mock treatment 1.00153985E8 6000000.0 0.52 1.00557812E8 4450000.0 0.39 0.642 0.9902 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F04 mock treatment 9.267394E7 -1480000.0 -0.13 9.3266095E7 -2840000.0 -0.25 -0.2661 -0.9524 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F05 mock treatment 9.6623697E7 2470000.0 0.21 9.8540159E7 2440000.0 0.21 0.3015 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F06 mock treatment 9.2471053E7 -1680000.0 -0.15 9.2130338E7 -3970000.0 -0.35 -0.3488 -0.9252 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F07 mock treatment 9.1657769E7 -2500000.0 -0.22 9.2009442E7 -4090000.0 -0.36 -0.4059 -0.9705 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F08 mock treatment 8.4793622E7 -9360000.0 -0.81 8.8382946E7 -7720000.0 -0.68 -1.0496 -0.996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F09 mock treatment 9.0589322E7 -3570000.0 -0.31 9.1377602E7 -4730000.0 -0.41 -0.5103 -0.9894 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F10 mock treatment 7.8837113E7 -1.53E7 -1.32 8.535889E7 -1.07E7 -0.94 -1.6005 -0.986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F11 mock treatment 8.5866658E7 -8290000.0 -0.72 8.9377042E7 -6730000.0 -0.59 -0.9225 -0.9953 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F12 mock treatment 8.2624488E7 -1.15E7 -1.0 8.6511554E7 -9590000.0 -0.84 -1.2979 -0.9964 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F13 mock treatment 8.7803473E7 -6350000.0 -0.55 9.1046598E7 -5060000.0 -0.44 -0.7009 -0.9943 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F14 mock treatment 8.645841E7 -7700000.0 -0.66 8.4807156E7 -1.13E7 -0.99 -1.1692 -0.9813 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F15 mock treatment 9.0694436E7 -3460000.0 -0.3 9.3940726E7 -2160000.0 -0.19 -0.3452 -0.9757 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F16 mock treatment 8.921792E7 -4940000.0 -0.43 9.1473425E7 -4630000.0 -0.41 -0.5881 -0.9997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F17 mock treatment 1.00733203E8 6580000.0 0.57 9.998779E7 3880000.0 0.34 0.6421 0.9698 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F18 mock treatment 9.7191143E7 3040000.0 0.26 9.9187724E7 3080000.0 0.27 0.3762 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F19 mock treatment 9.4742407E7 587000.0 0.05 9.7930196E7 1830000.0 0.16 0.1489 0.8879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F20 mock treatment 9.7190969E7 3040000.0 0.26 9.6213105E7 109000.0 0.01 0.1922 0.7323 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F21 mock treatment 1.01432574E8 7280000.0 0.63 1.01753832E8 5650000.0 0.49 0.7941 0.9929 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F22 mock treatment 9.8398291E7 4240000.0 0.37 9.9963832E7 3860000.0 0.34 0.498 0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F23 mock treatment 1.0210494E8 7950000.0 0.69 1.04485848E8 8380000.0 0.73 1.0042 0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base F24 mock treatment 1.0146483E8 7310000.0 0.63 1.04057757E8 7950000.0 0.7 0.9386 0.9988 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G01 mock treatment 1.0477375E8 1.06E7 0.92 1.05568762E8 9460000.0 0.83 1.2342 0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G02 mock treatment 9.7964354E7 3810000.0 0.33 1.01975278E8 5870000.0 0.51 0.596 0.9768 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G03 mock treatment 9.8221536E7 4070000.0 0.35 9.9337448E7 3230000.0 0.28 0.4484 0.9943 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G04 mock treatment 9.5921136E7 1770000.0 0.15 9.8034611E7 1930000.0 0.17 0.2273 0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G05 mock treatment 9.3292617E7 -862000.0 -0.07 9.21745E7 -3930000.0 -0.34 -0.2959 -0.8408 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G06 mock treatment 9.2204124E7 -1950000.0 -0.17 9.2877057E7 -3230000.0 -0.28 -0.3189 -0.9695 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G07 mock treatment 8.9661929E7 -4490000.0 -0.39 9.5429304E7 -675000.0 -0.06 -0.3162 -0.8055 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G08 mock treatment 8.6747213E7 -7410000.0 -0.64 8.9866372E7 -6240000.0 -0.55 -0.8385 -0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G09 mock treatment 9.2315791E7 -1840000.0 -0.16 9.0652526E7 -5450000.0 -0.48 -0.4497 -0.8943 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G10 mock treatment 8.3163226E7 -1.1E7 -0.95 8.6059811E7 -1.0E7 -0.88 -1.2929 -0.9993 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G11 mock treatment 8.2677562E7 -1.15E7 -0.99 8.6903059E7 -9200000.0 -0.81 -1.2704 -0.9947 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G12 mock treatment 8.7236716E7 -6920000.0 -0.6 9.3224539E7 -2880000.0 -0.25 -0.6007 -0.9263 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G13 mock treatment 8.5841863E7 -8310000.0 -0.72 8.8250256E7 -7850000.0 -0.69 -0.9938 -0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G14 mock treatment 8.5762759E7 -8390000.0 -0.72 9.0308123E7 -5800000.0 -0.51 -0.8712 -0.9848 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G15 mock treatment 8.2326888E7 -1.18E7 -1.02 8.8004028E7 -8100000.0 -0.71 -1.2237 -0.9841 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G16 mock treatment 9.1255846E7 -2900000.0 -0.25 9.2445503E7 -3660000.0 -0.32 -0.4035 -0.9926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G17 mock treatment 9.1286052E7 -2870000.0 -0.25 9.2523539E7 -3580000.0 -0.31 -0.3968 -0.9932 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G18 mock treatment 9.6382534E7 2230000.0 0.19 9.8000654E7 1900000.0 0.17 0.2534 0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G19 mock treatment 9.6949675E7 2790000.0 0.24 9.9621449E7 3520000.0 0.31 0.3883 0.9928 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G20 mock treatment 9.9460935E7 5310000.0 0.46 9.8411674E7 2310000.0 0.2 0.4668 0.9322 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G21 mock treatment 9.835227E7 4200000.0 0.36 1.02592305E8 6490000.0 0.57 0.6578 0.9765 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G22 mock treatment 1.03371927E8 9220000.0 0.8 1.05177916E8 9070000.0 0.79 1.1244 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G23 mock treatment 1.04401949E8 1.02E7 0.89 1.00381812E8 4280000.0 0.37 0.8905 0.9267 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base G24 mock treatment 1.0740344E8 1.32E7 1.14 1.06456007E8 1.04E7 0.91 1.4497 0.9933 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H01 mock treatment 9.5058517E7 903000.0 0.08 1.05924274E8 9820000.0 0.86 0.6629 0.7681 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H02 mock treatment 9.5610965E7 1460000.0 0.13 1.0010456E8 4000000.0 0.35 0.3365 0.9045 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H03 mock treatment 1.02297458E8 8140000.0 0.7 1.04063755E8 7960000.0 0.7 0.9899 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H04 mock treatment 9.2465251E7 -1690000.0 -0.15 8.9407768E7 -6700000.0 -0.59 -0.5176 -0.857 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H05 mock treatment 9.5833223E7 1680000.0 0.14 9.7446983E7 1340000.0 0.12 0.1856 0.9946 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H06 mock treatment 9.2108811E7 -2050000.0 -0.18 9.1822354E7 -4280000.0 -0.37 -0.39 -0.9412 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H07 mock treatment 9.4849332E7 694000.0 0.06 9.480372E7 -1300000.0 -0.11 -0.0381 -0.296 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H08 mock treatment 8.5246509E7 -8910000.0 -0.77 8.7788743E7 -8320000.0 -0.73 -1.0587 -0.9996 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H09 mock treatment 8.8846223E7 -5310000.0 -0.46 9.3417337E7 -2690000.0 -0.24 -0.4905 -0.9519 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H10 mock treatment 8.2837511E7 -1.13E7 -0.98 8.6039159E7 -1.01E7 -0.88 -1.3141 -0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H11 mock treatment 8.858525E7 -5570000.0 -0.48 9.2224744E7 -3880000.0 -0.34 -0.5803 -0.9854 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H12 mock treatment 8.5735418E7 -8420000.0 -0.73 8.9255754E7 -6850000.0 -0.6 -0.938 -0.9954 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H13 mock treatment 9.1257802E7 -2900000.0 -0.25 9.3908811E7 -2200000.0 -0.19 -0.3128 -0.9915 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H14 mock treatment 8.674041E7 -7410000.0 -0.64 8.9919451E7 -6180000.0 -0.54 -0.8356 -0.9965 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H15 mock treatment 8.5253522E7 -8900000.0 -0.77 8.7094662E7 -9010000.0 -0.79 -1.1012 -0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H16 mock treatment 8.6556099E7 -7600000.0 -0.66 8.6596333E7 -9510000.0 -0.83 -1.0525 -0.9931 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H17 mock treatment 9.448527E7 330000.0 0.03 9.8440688E7 2340000.0 0.2 0.1648 0.798 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H18 mock treatment 9.3642164E7 -513000.0 -0.04 9.5509941E7 -594000.0 -0.05 -0.0681 -0.9968 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H19 mock treatment 1.02580549E8 8430000.0 0.73 1.00368001E8 4260000.0 0.37 0.7784 0.9518 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H20 mock treatment 9.30294E7 -1130000.0 -0.1 9.7887651E7 1780000.0 0.16 0.0416 0.2263 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H21 mock treatment 1.03542731E8 9390000.0 0.81 1.04333931E8 8230000.0 0.72 1.0826 0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H22 mock treatment 1.00662881E8 6510000.0 0.56 9.9937252E7 3830000.0 0.34 0.6347 0.9696 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H23 mock treatment 1.05300515E8 1.11E7 0.96 1.07134058E8 1.1E7 0.97 1.3633 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base H24 mock treatment 1.06194257E8 1.2E7 1.04 1.06661643E8 1.06E7 0.92 1.3886 0.9983 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I01 mock treatment 1.15791587E8 2.16E7 1.87 1.07819248E8 1.17E7 1.03 2.0464 0.9601 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I02 mock treatment 1.01412636E8 7260000.0 0.63 1.02240303E8 6140000.0 0.54 0.823 0.997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I03 mock treatment 1.00141607E8 5990000.0 0.52 1.00300506E8 4200000.0 0.37 0.6253 0.986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I04 mock treatment 9.6516183E7 2360000.0 0.2 9.7237398E7 1130000.0 0.1 0.2143 0.9451 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I05 mock treatment 9.7522035E7 3370000.0 0.29 9.8557012E7 2450000.0 0.21 0.3574 0.9888 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I06 mock treatment 9.2525063E7 -1630000.0 -0.14 9.3379416E7 -2720000.0 -0.24 -0.2682 -0.9684 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I07 mock treatment 9.4862187E7 707000.0 0.06 9.4287862E7 -1820000.0 -0.16 -0.0692 -0.4065 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I08 mock treatment 8.792887E7 -6230000.0 -0.54 8.657937E7 -9520000.0 -0.83 -0.9697 -0.9775 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I09 mock treatment 9.152899E7 -2630000.0 -0.23 9.1005714E7 -5100000.0 -0.45 -0.4759 -0.9508 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I10 mock treatment 8.6671244E7 -7480000.0 -0.65 8.6649816E7 -9450000.0 -0.83 -1.0422 -0.9925 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I11 mock treatment 8.6084149E7 -8070000.0 -0.7 9.103794E7 -5070000.0 -0.44 -0.8065 -0.9761 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I12 mock treatment 8.6585543E7 -7570000.0 -0.65 8.5757803E7 -1.03E7 -0.91 -1.1026 -0.9872 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I13 mock treatment 8.8918119E7 -5240000.0 -0.45 9.3057765E7 -3050000.0 -0.27 -0.5084 -0.9682 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I14 mock treatment 8.4723986E7 -9430000.0 -0.81 9.010354E7 -6000000.0 -0.53 -0.9473 -0.9775 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I15 mock treatment 8.7778974E7 -6380000.0 -0.55 9.2367721E7 -3740000.0 -0.33 -0.6207 -0.969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I16 mock treatment 8.7470311E7 -6680000.0 -0.58 9.1945205E7 -4160000.0 -0.36 -0.6656 -0.9753 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I17 mock treatment 9.261483E7 -1540000.0 -0.13 9.5774159E7 -330000.0 -0.03 -0.1145 -0.841 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I18 mock treatment 9.2725507E7 -1430000.0 -0.12 9.6304359E7 200000.0 0.02 -0.0749 -0.6008 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I19 mock treatment 9.6292659E7 2140000.0 0.18 9.8942162E7 2840000.0 0.25 0.3062 0.9893 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I20 mock treatment 9.6415737E7 2260000.0 0.2 1.00651717E8 4550000.0 0.4 0.4195 0.9463 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I21 mock treatment 1.02646209E8 8490000.0 0.73 9.980074E7 3700000.0 0.32 0.7473 0.9323 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I22 mock treatment 1.00994005E8 6840000.0 0.59 9.9593212E7 3490000.0 0.31 0.6336 0.9529 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I23 mock treatment 1.06030672E8 1.19E7 1.03 1.05159524E8 9060000.0 0.79 1.2857 0.9919 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base I24 mock treatment 1.01760226E8 7610000.0 0.66 1.0547439E8 9370000.0 0.82 1.0443 0.994 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J01 mock treatment 1.03427597E8 9270000.0 0.8 1.09064432E8 1.3E7 1.13 1.3683 0.9855 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J02 mock treatment 9.5036202E7 881000.0 0.08 1.01337607E8 5230000.0 0.46 0.3777 0.8134 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J03 mock treatment 1.00583253E8 6430000.0 0.56 1.01063338E8 4960000.0 0.43 0.6995 0.9926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J04 mock treatment 9.3133275E7 -1020000.0 -0.09 9.8235128E7 2130000.0 0.19 0.0695 0.3367 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J05 mock treatment 9.7306767E7 3150000.0 0.27 1.00178023E8 4070000.0 0.36 0.4446 0.9911 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J06 mock treatment 8.5602087E7 -8550000.0 -0.74 9.3680847E7 -2420000.0 -0.21 -0.6723 -0.8748 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J07 mock treatment 9.3341297E7 -814000.0 -0.07 9.7082943E7 979000.0 0.09 0.0109 0.098 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J08 mock treatment 8.470118E7 -9450000.0 -0.82 8.7909182E7 -8200000.0 -0.72 -1.0845 -0.9979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J09 mock treatment 8.5622041E7 -8530000.0 -0.74 9.4658276E7 -1450000.0 -0.13 -0.6106 -0.8166 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J10 mock treatment 8.2949291E7 -1.12E7 -0.97 8.6133871E7 -9970000.0 -0.87 -1.3014 -0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J11 mock treatment 8.8152556E7 -6000000.0 -0.52 9.4399477E7 -1700000.0 -0.15 -0.4721 -0.8751 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J12 mock treatment 8.5350164E7 -8800000.0 -0.76 8.792851E7 -8180000.0 -0.72 -1.0437 -0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J13 mock treatment 9.3521995E7 -633000.0 -0.05 9.389316E7 -2210000.0 -0.19 -0.1755 -0.8727 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J14 mock treatment 8.3229841E7 -1.09E7 -0.94 9.1998031E7 -4110000.0 -0.36 -0.9214 -0.9125 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J15 mock treatment 9.1643578E7 -2510000.0 -0.22 9.5003784E7 -1100000.0 -0.1 -0.2215 -0.9332 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J16 mock treatment 8.7296437E7 -6860000.0 -0.59 9.2314422E7 -3790000.0 -0.33 -0.6534 -0.9624 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J17 mock treatment 9.206633E7 -2090000.0 -0.18 9.7862907E7 1760000.0 0.15 -0.0187 -0.079 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J18 mock treatment 8.8693377E7 -5460000.0 -0.47 9.4202113E7 -1900000.0 -0.17 -0.4513 -0.9021 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J19 mock treatment 9.4169739E7 14600.0 0.0 9.7282099E7 1180000.0 0.1 0.0738 0.7157 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J20 mock treatment 9.1076497E7 -3080000.0 -0.27 9.751827E7 1410000.0 0.12 -0.1005 -0.3427 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J21 mock treatment 1.01889271E8 7730000.0 0.67 1.04360178E8 8260000.0 0.72 0.9833 0.9992 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J22 mock treatment 9.3717307E7 -438000.0 -0.04 9.7552121E7 1450000.0 0.13 0.0629 0.4754 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J23 mock treatment 1.06847222E8 1.27E7 1.1 1.08952618E8 1.28E7 1.12 1.5703 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base J24 mock treatment 1.01854323E8 7700000.0 0.66 1.04741767E8 8640000.0 0.76 1.0048 0.998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K01 mock treatment 1.15480563E8 2.13E7 1.84 9.0287849E7 -5820000.0 -0.51 0.9425 0.4932 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K02 mock treatment 9.8931276E7 4780000.0 0.41 8.3091852E7 -1.3E7 -1.14 -0.5136 -0.424 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K03 mock treatment 9.7402946E7 3250000.0 0.28 8.7485925E7 -8620000.0 -0.75 -0.335 -0.4163 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K04 mock treatment 9.5761289E7 1610000.0 0.14 7.0740219E7 -2.54E7 -2.22 -1.4715 -0.6616 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K05 mock treatment 1.02479015E8 8320000.0 0.72 8.9294859E7 -6810000.0 -0.6 0.087 0.0931 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K06 mock treatment 9.200638E7 -2150000.0 -0.19 9.4855153E7 -1250000.0 -0.11 -0.2085 -0.9681 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K07 mock treatment 9.4117116E7 -38000.0 0.0 9.4851807E7 -1250000.0 -0.11 -0.0798 -0.7279 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K08 mock treatment 8.8430224E7 -5720000.0 -0.49 9.1682316E7 -4420000.0 -0.39 -0.6233 -0.9926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K09 mock treatment 9.3132767E7 -1020000.0 -0.09 9.1639522E7 -4460000.0 -0.39 -0.3387 -0.8456 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K10 mock treatment 8.7574131E7 -6580000.0 -0.57 9.2667698E7 -3440000.0 -0.3 -0.6146 -0.9557 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K11 mock treatment 8.6222813E7 -7930000.0 -0.69 7.9888222E7 -1.62E7 -1.42 -1.488 -0.9442 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K12 mock treatment 9.0993965E7 -3160000.0 -0.27 8.6307292E7 -9800000.0 -0.86 -0.7993 -0.8883 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K13 mock treatment 9.0895073E7 -3260000.0 -0.28 9.4750035E7 -1350000.0 -0.12 -0.2829 -0.926 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K14 mock treatment 8.562208E7 -8530000.0 -0.74 9.4941351E7 -1160000.0 -0.1 -0.5931 -0.7972 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K15 mock treatment 8.8392604E7 -5760000.0 -0.5 8.9452025E7 -6650000.0 -0.58 -0.7636 -0.997 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K16 mock treatment 9.3872061E7 -283000.0 -0.02 8.7890417E7 -8210000.0 -0.72 -0.5256 -0.7307 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K17 mock treatment 9.6150877E7 2000000.0 0.17 9.911104E7 3010000.0 0.26 0.308 0.979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K18 mock treatment 9.0986667E7 -3170000.0 -0.27 9.7509062E7 1400000.0 0.12 -0.1066 -0.3552 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K19 mock treatment 1.01455399E8 7300000.0 0.63 9.5274346E7 -830000.0 -0.07 0.3945 0.6215 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K20 mock treatment 9.5163643E7 1010000.0 0.09 1.0183816E8 5730000.0 0.5 0.4164 0.8176 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K21 mock treatment 1.03637826E8 9480000.0 0.82 1.06067388E8 9960000.0 0.87 1.1957 0.9995 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K22 mock treatment 1.0312362E8 8970000.0 0.77 1.03254389E8 7150000.0 0.63 0.9902 0.9944 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K23 mock treatment 1.04080617E8 9930000.0 0.86 1.04908796E8 8800000.0 0.77 1.1511 0.9986 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base K24 mock treatment 1.0773069E8 1.36E7 1.17 9.8494948E7 2390000.0 0.21 0.9771 0.8203 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L01 mock treatment 1.01219961E8 7060000.0 0.61 9.7543953E7 1440000.0 0.13 0.5206 0.8355 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L02 mock treatment 9.2972541E7 -1180000.0 -0.1 7.9280935E7 -1.68E7 -1.47 -1.1133 -0.7543 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L03 mock treatment 9.1514224E7 -2640000.0 -0.23 8.3833186E7 -1.23E7 -1.07 -0.9207 -0.8386 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L04 mock treatment 9.1178671E7 -2980000.0 -0.26 7.7346578E7 -1.88E7 -1.64 -1.3426 -0.808 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L05 mock treatment 9.292567E7 -1230000.0 -0.11 9.865914E7 2550000.0 0.22 0.083 0.3354 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L06 mock treatment 8.710668E7 -7050000.0 -0.61 9.229827E7 -3810000.0 -0.33 -0.666 -0.9597 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L07 mock treatment 9.7038496E7 2880000.0 0.25 1.00980256E8 4880000.0 0.43 0.4779 0.9671 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L08 mock treatment 8.6279648E7 -7880000.0 -0.68 8.9402849E7 -6700000.0 -0.59 -0.8957 -0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L09 mock treatment 9.2309745E7 -1850000.0 -0.16 9.4910282E7 -1190000.0 -0.1 -0.1866 -0.979 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L10 mock treatment 9.1153759E7 -3000000.0 -0.26 8.956971E7 -6530000.0 -0.57 -0.5877 -0.936 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L11 mock treatment 9.5174805E7 1020000.0 0.09 9.7806542E7 1700000.0 0.15 0.1676 0.9685 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L12 mock treatment 8.3862997E7 -1.03E7 -0.89 9.6935973E7 832000.0 0.07 -0.5771 -0.647 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L13 mock treatment 9.1857239E7 -2300000.0 -0.2 8.864364E7 -7460000.0 -0.65 -0.602 -0.8822 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L14 mock treatment 8.4877878E7 -9280000.0 -0.8 9.3464078E7 -2640000.0 -0.23 -0.73 -0.8753 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L15 mock treatment 9.3472962E7 -682000.0 -0.06 8.6564268E7 -9540000.0 -0.83 -0.632 -0.7551 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L16 mock treatment 9.2122679E7 -2030000.0 -0.18 7.9843343E7 -1.63E7 -1.42 -1.1304 -0.7884 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L17 mock treatment 9.7699566E7 3540000.0 0.31 9.7240543E7 1140000.0 0.1 0.2868 0.891 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L18 mock treatment 8.8778982E7 -5380000.0 -0.46 9.4212437E7 -1890000.0 -0.17 -0.4454 -0.9035 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L19 mock treatment 1.00993176E8 6840000.0 0.59 1.01811594E8 5710000.0 0.5 0.7708 0.9965 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L20 mock treatment 9.6460251E7 2310000.0 0.2 1.0087247E8 4770000.0 0.42 0.4359 0.9427 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L21 mock treatment 1.07557519E8 1.34E7 1.16 9.7283808E7 1180000.0 0.1 0.8915 0.7671 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L22 mock treatment 9.8090003E7 3930000.0 0.34 1.02288126E8 6180000.0 0.54 0.623 0.9749 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L23 mock treatment 1.0539386E8 1.12E7 0.97 1.10921098E8 1.48E7 1.3 1.6033 0.9898 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base L24 mock treatment 1.04453419E8 1.03E7 0.89 1.06254046E8 1.01E7 0.89 1.2571 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M01 mock treatment 1.15797637E8 2.16E7 1.87 1.14079485E8 1.8E7 1.57 2.4342 0.9963 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M02 mock treatment 9.8604793E7 4450000.0 0.38 1.03944675E8 7840000.0 0.69 0.757 0.9625 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M03 mock treatment 9.9805047E7 5650000.0 0.49 9.8530687E7 2430000.0 0.21 0.4952 0.9305 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M04 mock treatment 8.8279628E7 -5880000.0 -0.51 1.00493548E8 4390000.0 0.38 -0.0872 -0.137 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M05 mock treatment 9.951266E7 5360000.0 0.46 1.00149932E8 4050000.0 0.35 0.5776 0.9913 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M06 mock treatment 9.252699E7 -1630000.0 -0.14 9.1954373E7 -4150000.0 -0.36 -0.3562 -0.9147 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M07 mock treatment 9.1229801E7 -2930000.0 -0.25 9.5237664E7 -867000.0 -0.08 -0.2323 -0.8805 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M08 mock treatment 8.7999094E7 -6160000.0 -0.53 8.6377409E7 -9730000.0 -0.85 -0.9779 -0.9743 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M09 mock treatment 9.2199753E7 -1960000.0 -0.17 9.6938856E7 835000.0 0.07 -0.0678 -0.3683 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M10 mock treatment 8.4818484E7 -9340000.0 -0.81 9.588378E7 -220000.0 -0.02 -0.5839 -0.7238 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M11 mock treatment 9.1825021E7 -2330000.0 -0.2 8.752285E7 -8580000.0 -0.75 -0.6734 -0.866 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M12 mock treatment 8.2779323E7 -1.14E7 -0.98 8.5892967E7 -1.02E7 -0.89 -1.3267 -0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M13 mock treatment 9.5902785E7 1750000.0 0.15 9.7360831E7 1260000.0 0.11 0.1845 0.9879 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M14 mock treatment 8.6104132E7 -8050000.0 -0.7 8.5348204E7 -1.08E7 -0.94 -1.1573 -0.9889 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M15 mock treatment 9.567242E7 1520000.0 0.13 8.2226621E7 -1.39E7 -1.21 -0.7661 -0.6272 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M16 mock treatment 8.7430659E7 -6720000.0 -0.58 8.882307E7 -7280000.0 -0.64 -0.8613 -0.9989 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M17 mock treatment 8.871301E7 -5440000.0 -0.47 9.8191855E7 2090000.0 0.18 -0.2032 -0.4029 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M18 mock treatment 9.248814E7 -1670000.0 -0.14 8.9185044E7 -6920000.0 -0.61 -0.53 -0.8515 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M19 mock treatment 9.9864961E7 5710000.0 0.49 9.9888202E7 3780000.0 0.33 0.5829 0.9812 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M20 mock treatment 9.0764326E7 -3390000.0 -0.29 1.00822368E8 4720000.0 0.41 0.0849 0.1677 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M21 mock treatment 1.02777395E8 8620000.0 0.74 8.933391E7 -6770000.0 -0.59 0.1076 0.1131 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M22 mock treatment 9.3598998E7 -556000.0 -0.05 7.9434093E7 -1.67E7 -1.46 -1.0656 -0.73 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M23 mock treatment 1.03546714E8 9390000.0 0.81 1.118233E8 1.57E7 1.38 1.5463 0.9683 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base M24 mock treatment 1.0804827E8 1.39E7 1.2 1.01423889E8 5320000.0 0.47 1.1777 0.915 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N01 mock treatment 1.01826639E8 7670000.0 0.66 1.08478367E8 1.24E7 1.08 1.2343 0.9722 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N02 mock treatment 9.8507266E7 4350000.0 0.38 1.02547372E8 6440000.0 0.56 0.6645 0.9806 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N03 mock treatment 1.05017575E8 1.09E7 0.94 9.5806385E7 -298000.0 -0.03 0.645 0.6872 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N04 mock treatment 8.6473748E7 -7680000.0 -0.66 1.01055873E8 4950000.0 0.43 -0.1627 -0.2053 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N05 mock treatment 7.8535651E7 -1.56E7 -1.35 9.9635594E7 3530000.0 0.31 -0.7354 -0.5314 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N06 mock treatment 9.4362572E7 207000.0 0.02 8.8425372E7 -7680000.0 -0.67 -0.4625 -0.688 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N07 mock treatment 9.184543E7 -2310000.0 -0.2 1.00192362E8 4090000.0 0.36 0.1119 0.2732 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N08 mock treatment 9.1391207E7 -2760000.0 -0.24 9.4218541E7 -1890000.0 -0.17 -0.2855 -0.9837 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N09 mock treatment 9.5625779E7 1470000.0 0.13 8.9443012E7 -6660000.0 -0.58 -0.3224 -0.5404 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N10 mock treatment 8.5542971E7 -8610000.0 -0.74 9.4702111E7 -1400000.0 -0.12 -0.6128 -0.8128 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N11 mock treatment 9.3928485E7 -227000.0 -0.02 9.3249242E7 -2850000.0 -0.25 -0.1905 -0.7602 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N12 mock treatment 8.4740476E7 -9410000.0 -0.81 8.4628563E7 -1.15E7 -1.0 -1.2852 -0.9945 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N13 mock treatment 9.603181E7 1880000.0 0.16 9.7949899E7 1850000.0 0.16 0.2288 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N14 mock treatment 8.9334959E7 -4820000.0 -0.42 9.3833005E7 -2270000.0 -0.2 -0.4349 -0.9428 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N15 mock treatment 8.5838977E7 -8320000.0 -0.72 7.4260665E7 -2.18E7 -1.91 -1.8597 -0.9106 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N16 mock treatment 9.0937185E7 -3220000.0 -0.28 9.3406965E7 -2700000.0 -0.24 -0.3635 -0.9967 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N17 mock treatment 9.7612158E7 3460000.0 0.3 9.8729041E7 2620000.0 0.23 0.3736 0.9916 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N18 mock treatment 8.6167915E7 -7990000.0 -0.69 9.0034138E7 -6070000.0 -0.53 -0.8635 -0.9917 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N19 mock treatment 9.9720466E7 5570000.0 0.48 9.7445241E7 1340000.0 0.12 0.4229 0.8546 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N20 mock treatment 9.1882317E7 -2270000.0 -0.2 9.8113186E7 2010000.0 0.18 -0.0145 -0.055 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N21 mock treatment 9.0138977E7 -4020000.0 -0.35 7.7558596E7 -1.85E7 -1.62 -1.393 -0.8393 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N22 mock treatment 9.9806601E7 5650000.0 0.49 8.9436673E7 -6670000.0 -0.58 -0.0675 -0.0887 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N23 mock treatment 1.03942011E8 9790000.0 0.85 1.07199617E8 1.11E7 0.97 1.2844 0.9976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base N24 mock treatment 9.8885256E7 4730000.0 0.41 9.8784837E7 2680000.0 0.23 0.4548 0.9653 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O01 mock treatment 8.6849233E7 -7310000.0 -0.63 1.00842811E8 4740000.0 0.41 -0.153 -0.2026 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O02 mock treatment 9.9694311E7 5540000.0 0.48 8.4522024E7 -1.16E7 -1.01 -0.3785 -0.3376 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O03 mock treatment 9.9633814E7 5480000.0 0.47 1.01330902E8 5230000.0 0.46 0.6581 0.9999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O04 mock treatment 9.9222244E7 5070000.0 0.44 1.11291213E8 1.52E7 1.33 1.2493 0.8928 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O05 mock treatment 1.04478467E8 1.03E7 0.89 1.04556128E8 8450000.0 0.74 1.1535 0.9957 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O06 mock treatment 9.2540363E7 -1610000.0 -0.14 9.9752884E7 3650000.0 0.32 0.1272 0.365 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O07 mock treatment 1.0099094E8 6840000.0 0.59 1.01520354E8 5420000.0 0.47 0.7527 0.9941 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O08 mock treatment 9.4774545E7 619000.0 0.05 9.604503E7 -59200.0 -0.01 0.0342 0.6356 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O09 mock treatment 9.797961E7 3820000.0 0.33 9.7465893E7 1360000.0 0.12 0.3178 0.9051 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O10 mock treatment 9.1762274E7 -2390000.0 -0.21 9.5498599E7 -606000.0 -0.05 -0.1836 -0.8606 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O11 mock treatment 9.9311155E7 5160000.0 0.45 9.8479093E7 2370000.0 0.21 0.4619 0.9398 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O12 mock treatment 9.4923728E7 769000.0 0.07 9.3275044E7 -2830000.0 -0.25 -0.1281 -0.4999 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O13 mock treatment 9.5542385E7 1390000.0 0.12 1.02697674E8 6590000.0 0.58 0.4928 0.8361 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O14 mock treatment 9.5013202E7 858000.0 0.07 8.5770373E7 -1.03E7 -0.9 -0.5871 -0.647 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O15 mock treatment 9.7753935E7 3600000.0 0.31 9.7027178E7 923000.0 0.08 0.2769 0.8622 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O16 mock treatment 9.3150405E7 -1000000.0 -0.09 9.2418382E7 -3690000.0 -0.32 -0.2895 -0.8665 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O17 mock treatment 9.7516614E7 3360000.0 0.29 9.9945627E7 3840000.0 0.34 0.443 0.9973 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O18 mock treatment 9.2008079E7 -2150000.0 -0.19 9.8845668E7 2740000.0 0.24 0.0385 0.127 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O19 mock treatment 1.0352654E8 9370000.0 0.81 9.9802071E7 3700000.0 0.32 0.8012 0.9191 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O20 mock treatment 9.9728581E7 5570000.0 0.48 9.9866289E7 3760000.0 0.33 0.5732 0.9828 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O21 mock treatment 1.01975937E8 7820000.0 0.68 1.04799036E8 8690000.0 0.76 1.0157 0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O22 mock treatment 1.02709996E8 8550000.0 0.74 1.01695847E8 5590000.0 0.49 0.8685 0.98 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O23 mock treatment 1.06984063E8 1.28E7 1.11 1.07128309E8 1.1E7 0.96 1.4657 0.9976 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base O24 mock treatment 1.05696909E8 1.15E7 1.0 1.06130435E8 1.0E7 0.88 1.3254 0.998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P01 mock treatment 8.2841604E7 -1.13E7 -0.98 9.6312862E7 209000.0 0.02 -0.6781 -0.6938 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P02 mock treatment 1.01596788E8 7440000.0 0.64 9.26826E7 -3420000.0 -0.3 0.2428 0.3423 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P03 mock treatment 1.06884965E8 1.27E7 1.1 9.5288038E7 -816000.0 -0.07 0.727 0.6598 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P04 mock treatment 9.9336579E7 5180000.0 0.45 9.8896297E7 2790000.0 0.24 0.4892 0.9595 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P05 mock treatment 1.03678698E8 9520000.0 0.82 9.9797585E7 3690000.0 0.32 0.8102 0.9167 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P06 mock treatment 9.7033903E7 2880000.0 0.25 9.882205E7 2720000.0 0.24 0.344 0.9998 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P07 mock treatment 1.01438898E8 7280000.0 0.63 9.9569209E7 3460000.0 0.3 0.6593 0.944 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P08 mock treatment 9.6360923E7 2210000.0 0.19 9.6623248E7 519000.0 0.05 0.1668 0.8518 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P09 mock treatment 9.9290595E7 5140000.0 0.44 1.01823342E8 5720000.0 0.5 0.6676 0.9982 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P10 mock treatment 9.6438481E7 2280000.0 0.2 9.7157136E7 1050000.0 0.09 0.2046 0.94 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P11 mock treatment 1.01849146E8 7690000.0 0.66 1.00306013E8 4200000.0 0.37 0.7299 0.9611 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P12 mock treatment 9.2473806E7 -1680000.0 -0.15 9.5431366E7 -673000.0 -0.06 -0.1443 -0.921 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P13 mock treatment 1.02041045E8 7890000.0 0.68 8.7097825E7 -9010000.0 -0.79 -0.0757 -0.0727 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P14 mock treatment 9.7968768E7 3810000.0 0.33 7.9572487E7 -1.65E7 -1.45 -0.7901 -0.5325 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P15 mock treatment 1.00480947E8 6330000.0 0.55 9.8426393E7 2320000.0 0.2 0.5301 0.9093 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P16 mock treatment 9.5417413E7 1260000.0 0.11 9.1163934E7 -4940000.0 -0.43 -0.2286 -0.5127 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P17 mock treatment 1.02115031E8 7960000.0 0.69 1.03189595E8 7090000.0 0.62 0.9246 0.9987 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P18 mock treatment 9.7947906E7 3790000.0 0.33 9.6466761E7 363000.0 0.03 0.2541 0.772 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P19 mock treatment 1.03985604E8 9830000.0 0.85 1.04803318E8 8700000.0 0.76 1.1387 0.9985 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P20 mock treatment 9.7542165E7 3390000.0 0.29 1.02243178E8 6140000.0 0.54 0.5868 0.9592 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P21 mock treatment 1.06788712E8 1.26E7 1.09 1.08342322E8 1.22E7 1.07 1.5289 1.0 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P22 mock treatment 1.03711967E8 9560000.0 0.83 1.04155023E8 8050000.0 0.7 1.0819 0.9969 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P23 mock treatment 1.0847793E8 1.43E7 1.24 1.05334997E8 9230000.0 0.81 1.446 0.9787 1033.0025 CellTiterBlue(1033.0025) PKCoreAssaySet 1033.0025.Base P24 mock treatment 1.0708649E8 1.29E7 1.12 1.08164075E8 1.21E7 1.06 1.5361 0.9996