ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A01 compound treatment 413286.0 -35000.0 -0.21 439546.0 -51700.0 -0.29 -0.3552 -0.9857 1965040 CMLD1_000001 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A02 compound treatment 354369.0 -93900.0 -0.56 466733.0 -24500.0 -0.14 -0.4939 -0.8573 1965041 CMLD1_000002 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A03 compound treatment 225676.0 -223000.0 -1.32 373190.0 -118000.0 -0.67 -1.4116 -0.9504 1965042 CMLD1_000003 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A04 compound treatment 112391.0 -336000.0 -2.0 197069.0 -294000.0 -1.67 -2.5965 -0.9961 1965043 CMLD1_000004 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A05 compound treatment 140846.0 -307000.0 -1.83 188983.0 -302000.0 -1.72 -2.5093 -0.9995 1965044 CMLD1_000005 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A06 compound treatment 193050.0 -255000.0 -1.52 229672.0 -262000.0 -1.49 -2.126 -0.9999 1965045 CMLD1_000006 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A07 compound treatment 379504.0 -68800.0 -0.41 270128.0 -221000.0 -1.26 -1.1787 -0.8913 1965046 CMLD1_000007 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A08 compound treatment 268633.0 -180000.0 -1.07 284300.0 -207000.0 -1.18 -1.5883 -0.9989 1965047 CMLD1_000008 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A09 compound treatment 350762.0 -97500.0 -0.58 145640.0 -346000.0 -1.97 -1.8002 -0.8784 1965048 CMLD1_000009 CCCCC=C[C@@H](NC(=O)Oc1cccc(c1)C(F)(F)F)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A10 compound treatment 344421.0 -104000.0 -0.62 440889.0 -50400.0 -0.29 -0.6396 -0.9389 1965049 CMLD1_000010 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(OC)cc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A11 compound treatment 303233.0 -145000.0 -0.86 104200.0 -387000.0 -2.2 -2.1669 -0.9165 1965050 CMLD1_000011 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3cccs3)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A12 compound treatment 326695.0 -122000.0 -0.72 366963.0 -124000.0 -0.71 -1.0115 -0.9999 1965051 CMLD1_000012 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A13 compound treatment 357861.0 -90400.0 -0.54 580216.0 89000.0 0.51 -0.0228 -0.0309 1965052 CMLD1_000013 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A14 compound treatment 61114.0 -387000.0 -2.3 77244.0 -414000.0 -2.35 -3.2942 -0.9999 1965053 CMLD1_000014 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A15 compound treatment 463890.0 15600.0 0.09 437505.0 -53800.0 -0.31 -0.1505 -0.471 1965054 CMLD1_000015 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A16 compound treatment 379654.0 -68600.0 -0.41 408054.0 -83200.0 -0.47 -0.6234 -0.9973 1965055 CMLD1_000016 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A17 compound treatment 166846.0 -281000.0 -1.67 181393.0 -310000.0 -1.76 -2.4304 -0.9997 1965056 CMLD1_000017 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)C(C)(C)C)c2ccc(cc2)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A18 compound treatment 70807.0 -377000.0 -2.25 72758.0 -419000.0 -2.38 -3.2714 -0.9996 1965057 CMLD1_000018 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A19 compound treatment 442357.0 -5930.0 -0.04 250670.0 -241000.0 -1.37 -0.9924 -0.7251 1965058 CMLD1_000019 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A20 compound treatment 482232.0 33900.0 0.2 174336.0 -317000.0 -1.8 -1.1315 -0.6239 1965059 CMLD1_000020 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A21 compound treatment 143437.0 -305000.0 -1.81 85525.0 -406000.0 -2.31 -2.9144 -0.9929 1965060 CMLD1_000021 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A22 mock treatment 458639.0 10400.0 0.06 476082.0 -15200.0 -0.09 -0.0175 -0.1647 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A23 mock treatment 304745.0 -144000.0 -0.85 355641.0 -136000.0 -0.77 -1.1494 -0.9987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 A24 mock treatment 408987.0 -39300.0 -0.23 476016.0 -15200.0 -0.09 -0.2267 -0.9088 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B01 compound treatment 426796.0 -21500.0 -0.13 508057.0 16800.0 0.1 -0.0229 -0.1435 1965061 CMLD1_000022 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B02 compound treatment 442301.0 -5980.0 -0.04 491468.0 206.0 0.0 -0.0244 -0.6835 1965062 CMLD1_000023 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B03 compound treatment 461065.0 12800.0 0.08 498799.0 7540.0 0.04 0.0841 0.9632 1965063 CMLD1_000024 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B04 compound treatment 349189.0 -99100.0 -0.59 396525.0 -94700.0 -0.54 -0.798 -0.999 1965064 CMLD1_000025 CCOC(=O)N(CC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4)S(=O)(=O)c6ccc(C)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B05 compound treatment 416707.0 -31600.0 -0.19 504678.0 13400.0 0.08 -0.0789 -0.3892 1965065 CMLD1_000026 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B06 compound treatment 77298.0 -371000.0 -2.21 87489.0 -404000.0 -2.3 -3.1849 -0.9998 1965066 CMLD1_000027 CC(NP(=O)(c1ccccc1)c2ccccc2)C3(CC(=C)c4ccccc4)CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B07 compound treatment 424154.0 -24100.0 -0.14 523362.0 32100.0 0.18 0.0275 0.1185 1965067 CMLD1_000028 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B08 compound treatment 449781.0 1500.0 0.01 545320.0 54100.0 0.31 0.2237 0.7273 1965068 CMLD1_000029 COC(=O)C1(C)NCC2=C(C)C(=O)C(C)C2=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B09 compound treatment 459362.0 11100.0 0.07 480318.0 -10900.0 -0.06 0.0026 0.0287 1965069 CMLD1_000030 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B10 compound treatment 231565.0 -217000.0 -1.29 247872.0 -243000.0 -1.38 -1.8907 -0.9994 1965070 CMLD1_000031 COC(=O)C1(Cc2ccccc2)NCC3=C(C(C)C)C(=O)C(C)C3=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B11 compound treatment 449237.0 952.0 0.01 494439.0 3180.0 0.02 0.0168 0.8863 1965071 CMLD1_000032 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B12 compound treatment 73835.0 -374000.0 -2.23 74216.0 -417000.0 -2.37 -3.2528 -0.9995 1965072 CMLD1_000033 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCc5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B13 compound treatment 432619.0 -15700.0 -0.09 410576.0 -80700.0 -0.46 -0.3904 -0.8338 1965073 CMLD1_000034 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B14 compound treatment 459647.0 11400.0 0.07 488208.0 -3050.0 -0.02 0.0355 0.509 1965074 CMLD1_000035 COc1ccc(COC2OC[C@]3(C)[C@@H]4[C@H]2CCC5C(CO)C(CO)[C@@H](C)C(=C54)CN3C(=O)OC(C)(C)C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B15 compound treatment 427528.0 -20800.0 -0.12 411787.0 -79500.0 -0.45 -0.4069 -0.8685 1965075 CMLD1_000036 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B16 compound treatment 276761.0 -172000.0 -1.02 362196.0 -129000.0 -0.73 -1.2408 -0.9869 1965076 CMLD1_000037 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(F)cc5)C=C21)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B17 compound treatment 428236.0 -20000.0 -0.12 200906.0 -290000.0 -1.65 -1.2519 -0.7562 1965077 CMLD1_000038 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B18 compound treatment 445888.0 -2400.0 -0.01 410949.0 -80300.0 -0.46 -0.333 -0.7288 1965078 CMLD1_000039 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B19 compound treatment 521760.0 73500.0 0.44 442162.0 -49100.0 -0.28 0.1118 0.2154 1965079 CMLD1_000040 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B20 compound treatment 421979.0 -26300.0 -0.16 186834.0 -304000.0 -1.73 -1.3349 -0.7679 1965080 CMLD1_000041 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B21 compound treatment 470637.0 22400.0 0.13 441711.0 -49600.0 -0.28 -0.1052 -0.3376 1965081 CMLD1_000042 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B22 mock treatment 459166.0 10900.0 0.06 312775.0 -178000.0 -1.02 -0.6719 -0.6607 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B23 mock treatment 475384.0 27100.0 0.16 493957.0 2690.0 0.02 0.1249 0.7708 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 B24 mock treatment 626377.0 178000.0 1.06 515453.0 24200.0 0.14 0.8467 0.7922 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C01 compound treatment 477792.0 29500.0 0.18 533717.0 42500.0 0.24 0.2949 0.9878 1965082 CMLD1_000043 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC1(CCC2CC1=O)C2(C)C)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C02 compound treatment 71779.0 -377000.0 -2.24 63156.0 -428000.0 -2.43 -3.3059 -0.9991 1965083 CMLD1_000044 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C03 compound treatment 360425.0 -87900.0 -0.52 284677.0 -207000.0 -1.17 -1.2004 -0.9335 1965084 CMLD1_000045 CCCC=C(CCC)[C@@H](NC(=O)CCc1ccccc1)c2ccc(cc2)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C04 compound treatment 321204.0 -127000.0 -0.76 59425.0 -432000.0 -2.46 -2.2713 -0.8839 1965085 CMLD1_000046 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C05 compound treatment 307360.0 -141000.0 -0.84 344195.0 -147000.0 -0.84 -1.1844 -1.0 1965086 CMLD1_000047 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C06 compound treatment 168934.0 -279000.0 -1.66 214901.0 -276000.0 -1.57 -2.2869 -0.9996 1965087 CMLD1_000048 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C07 compound treatment 65288.0 -383000.0 -2.28 69846.0 -421000.0 -2.4 -3.3063 -0.9997 1965088 CMLD1_000049 CCCCC=C[C@@H](NC(=O)CCc1ccccc1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C08 compound treatment 324503.0 -124000.0 -0.74 359387.0 -132000.0 -0.75 -1.0512 -1.0 1965089 CMLD1_000050 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(C)onc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C09 compound treatment 292591.0 -156000.0 -0.93 116267.0 -375000.0 -2.13 -2.1631 -0.9303 1965090 CMLD1_000051 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C10 compound treatment 381551.0 -66700.0 -0.4 370627.0 -121000.0 -0.69 -0.7659 -0.9662 1965091 CMLD1_000052 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C11 compound treatment 393206.0 -55100.0 -0.33 388140.0 -103000.0 -0.59 -0.6465 -0.9622 1965092 CMLD1_000053 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccccc3)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C12 compound treatment 148538.0 -300000.0 -1.78 309902.0 -181000.0 -1.03 -1.9907 -0.9661 1965093 CMLD1_000054 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C13 compound treatment 380461.0 -67800.0 -0.4 352818.0 -138000.0 -0.79 -0.8421 -0.9518 1965094 CMLD1_000055 CCCCC=C[C@@H](NC(=O)c1ccccc1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C14 compound treatment 64127.0 -384000.0 -2.29 69392.0 -422000.0 -2.4 -3.313 -0.9997 1965095 CMLD1_000056 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C15 compound treatment 325429.0 -123000.0 -0.73 80387.0 -411000.0 -2.34 -2.1692 -0.886 1965096 CMLD1_000057 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C16 compound treatment 408361.0 -39900.0 -0.24 276416.0 -215000.0 -1.22 -1.0319 -0.8291 1965097 CMLD1_000058 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C17 compound treatment 322094.0 -126000.0 -0.75 305522.0 -186000.0 -1.06 -1.2779 -0.986 1965098 CMLD1_000059 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NS(=O)(=O)c3cccc4cccnc34)c5ccc(cc5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C18 compound treatment 350691.0 -97600.0 -0.58 338305.0 -153000.0 -0.87 -1.0258 -0.9807 1965099 CMLD1_000060 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(OC)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C19 compound treatment 295478.0 -153000.0 -0.91 347178.0 -144000.0 -0.82 -1.2224 -0.9986 1965100 CMLD1_000061 CC(C)(C)C(=O)N[C@@H](c1ccc(Cl)cc1)[C@]2(C)C[C@H]2C3CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C20 compound treatment 440641.0 -7640.0 -0.05 416117.0 -75100.0 -0.43 -0.3343 -0.778 1965101 CMLD1_000062 CCCCC=C[C@@H](NC(=O)OCC#C)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C21 compound treatment 261072.0 -187000.0 -1.11 237885.0 -253000.0 -1.44 -1.8067 -0.9919 1965060 CMLD1_000063 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C22 mock treatment 402736.0 -45500.0 -0.27 456582.0 -34700.0 -0.2 -0.3311 -0.9878 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C23 mock treatment 264472.0 -184000.0 -1.09 440125.0 -51100.0 -0.29 -0.9792 -0.865 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 C24 mock treatment 183606.0 -265000.0 -1.58 532843.0 41600.0 0.24 -0.9466 -0.5943 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D01 compound treatment 503387.0 55100.0 0.33 449398.0 -41900.0 -0.24 0.0635 0.1568 1965102 CMLD1_000064 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D02 compound treatment 345026.0 -103000.0 -0.61 297428.0 -194000.0 -1.1 -1.214 -0.9619 1965103 CMLD1_000065 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D03 compound treatment 436507.0 -11800.0 -0.07 471883.0 -19400.0 -0.11 -0.1275 -0.9761 1965104 CMLD1_000066 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D04 compound treatment 137411.0 -311000.0 -1.85 135524.0 -356000.0 -2.02 -2.7387 -0.999 1965105 CMLD1_000067 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D05 compound treatment 170167.0 -278000.0 -1.66 188150.0 -303000.0 -1.72 -2.3893 -0.9998 1965106 CMLD1_000068 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D06 compound treatment 437107.0 -11200.0 -0.07 406963.0 -84300.0 -0.48 -0.386 -0.7976 1965107 CMLD1_000069 CC(=O)N1CC2(CC2)CC1c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D07 compound treatment 51174.0 -397000.0 -2.36 70251.0 -421000.0 -2.39 -3.3641 -1.0 1965108 CMLD1_000070 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D08 compound treatment 365478.0 -82800.0 -0.49 410925.0 -80300.0 -0.46 -0.6715 -0.9993 1965109 CMLD1_000071 COC(=O)C1(C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D09 compound treatment 492105.0 43800.0 0.26 429931.0 -61300.0 -0.35 -0.0622 -0.1429 1965110 CMLD1_000072 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCn7cc(nc7C)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D10 compound treatment 475969.0 27700.0 0.16 350052.0 -141000.0 -0.8 -0.4513 -0.5506 1965111 CMLD1_000073 COC(=O)C1(Cc2ccccc2)NCC3=C(C(=O)C(C)C3=C1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D11 compound treatment 387276.0 -61000.0 -0.36 385062.0 -106000.0 -0.6 -0.6838 -0.9704 1965112 CMLD1_000074 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D12 compound treatment 72442.0 -376000.0 -2.24 77956.0 -413000.0 -2.35 -3.2436 -0.9997 1965113 CMLD1_000075 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccco5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D13 compound treatment 58210.0 -390000.0 -2.32 114087.0 -377000.0 -2.14 -3.1582 -0.9992 1965057 CMLD1_000076 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D14 compound treatment 74600.0 -374000.0 -2.22 80665.0 -411000.0 -2.33 -3.2236 -0.9997 1965114 CMLD1_000077 C[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D15 compound treatment 441076.0 -7210.0 -0.04 381961.0 -109000.0 -0.62 -0.4699 -0.7541 1965115 CMLD1_000078 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D16 compound treatment 346491.0 -102000.0 -0.61 381286.0 -110000.0 -0.63 -0.8706 -0.9999 1965116 CMLD1_000079 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(F)cc6)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D17 compound treatment 441692.0 -6590.0 -0.04 385963.0 -105000.0 -0.6 -0.4512 -0.7518 1965117 CMLD1_000080 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D18 compound treatment 190128.0 -258000.0 -1.54 455329.0 -35900.0 -0.2 -1.2309 -0.7942 1965118 CMLD1_000081 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D19 compound treatment 445167.0 -3120.0 -0.02 397236.0 -94000.0 -0.53 -0.3912 -0.7312 1965119 CMLD1_000082 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D20 compound treatment 330182.0 -118000.0 -0.7 390968.0 -100000.0 -0.57 -0.9003 -0.9946 1965120 CMLD1_000083 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D21 compound treatment 190222.0 -258000.0 -1.54 503526.0 12300.0 0.07 -1.0367 -0.6743 1965121 CMLD1_000084 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D22 mock treatment 376812.0 -71500.0 -0.43 408396.0 -82900.0 -0.47 -0.634 -0.9987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D23 mock treatment 450205.0 1920.0 0.01 421218.0 -70000.0 -0.4 -0.2736 -0.6865 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 D24 mock treatment 426935.0 -21400.0 -0.13 499532.0 8270.0 0.05 -0.0566 -0.4177 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E01 compound treatment 494547.0 46300.0 0.28 475359.0 -15900.0 -0.09 0.1307 0.4511 1965122 CMLD1_000085 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E02 compound treatment 269286.0 -179000.0 -1.07 345736.0 -146000.0 -0.83 -1.3385 -0.9922 1965123 CMLD1_000086 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E03 compound treatment 272198.0 -176000.0 -1.05 295343.0 -196000.0 -1.11 -1.5288 -0.9995 1965124 CMLD1_000087 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E04 compound treatment 366610.0 -81700.0 -0.49 374723.0 -117000.0 -0.66 -0.8123 -0.9884 1965125 CMLD1_000088 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E05 compound treatment 407010.0 -41300.0 -0.25 468400.0 -22900.0 -0.13 -0.2656 -0.9557 1965126 CMLD1_000089 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E06 compound treatment 312315.0 -136000.0 -0.81 306017.0 -185000.0 -1.05 -1.3171 -0.9915 1965127 CMLD1_000090 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E07 compound treatment 71595.0 -377000.0 -2.24 74247.0 -417000.0 -2.37 -3.2621 -0.9996 1965128 CMLD1_000091 CCCCC=C[C@@H](NC(=O)C(C)(C)C)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E08 compound treatment 281776.0 -167000.0 -0.99 296533.0 -195000.0 -1.11 -1.4838 -0.9985 1965129 CMLD1_000092 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E09 compound treatment 288929.0 -159000.0 -0.95 409242.0 -82000.0 -0.47 -1.0004 -0.9466 1965130 CMLD1_000093 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E10 compound treatment 234800.0 -213000.0 -1.27 245261.0 -246000.0 -1.4 -1.8876 -0.9988 1965131 CMLD1_000094 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E11 compound treatment 132561.0 -316000.0 -1.88 324759.0 -167000.0 -0.95 -1.9982 -0.9497 1965060 CMLD1_000095 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E12 compound treatment 323833.0 -124000.0 -0.74 324579.0 -167000.0 -0.95 -1.194 -0.9926 1965132 CMLD1_000096 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E13 compound treatment 358807.0 -89500.0 -0.53 356274.0 -135000.0 -0.77 -0.9194 -0.984 1965133 CMLD1_000097 CCCCC=C[C@@H](NC(=O)OCc1ccccc1Cl)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E14 compound treatment 461177.0 12900.0 0.08 442183.0 -49100.0 -0.28 -0.1431 -0.4944 1965134 CMLD1_000098 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E15 compound treatment 474903.0 26600.0 0.16 271679.0 -220000.0 -1.25 -0.771 -0.6125 1965135 CMLD1_000099 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E16 compound treatment 437061.0 -11200.0 -0.07 488319.0 -2940.0 -0.02 -0.0591 -0.8578 1965136 CMLD1_000100 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E17 compound treatment 311717.0 -137000.0 -0.81 98862.0 -392000.0 -2.23 -2.1526 -0.9064 1965137 CMLD1_000101 CC(=CC1CCCCC1)[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E18 compound treatment 50815.0 -397000.0 -2.37 65034.0 -426000.0 -2.42 -3.3866 -0.9999 1965138 CMLD1_000102 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E19 compound treatment 59596.0 -389000.0 -2.31 44557.0 -447000.0 -2.54 -3.432 -0.9989 1965139 CMLD1_000103 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccc(cc3)c4ccccc4)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E20 compound treatment 455993.0 7710.0 0.05 269559.0 -222000.0 -1.26 -0.8591 -0.6809 1965140 CMLD1_000104 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E21 compound treatment 378823.0 -69500.0 -0.41 122248.0 -369000.0 -2.1 -1.7762 -0.8304 1965141 CMLD1_000105 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccccc2)c3cccc(Cl)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E22 mock treatment 263665.0 -185000.0 -1.1 341885.0 -149000.0 -0.85 -1.3776 -0.9919 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E23 mock treatment 228696.0 -220000.0 -1.31 210444.0 -281000.0 -1.6 -2.0533 -0.995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 E24 mock treatment 450088.0 1800.0 0.01 546829.0 55600.0 0.32 0.231 0.7307 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F01 compound treatment 463289.0 15000.0 0.09 215190.0 -276000.0 -1.57 -1.047 -0.6658 1965142 CMLD1_000106 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CCOCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F02 compound treatment 358006.0 -90300.0 -0.54 202290.0 -289000.0 -1.64 -1.5419 -0.8918 1965143 CMLD1_000107 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F03 compound treatment 395193.0 -53100.0 -0.32 404896.0 -86400.0 -0.49 -0.5707 -0.9772 1965144 CMLD1_000108 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F04 compound treatment 65652.0 -383000.0 -2.28 29412.0 -462000.0 -2.63 -3.4674 -0.9975 1965145 CMLD1_000109 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5cccc(OC)c5)CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F05 compound treatment 301498.0 -147000.0 -0.87 172902.0 -318000.0 -1.81 -1.8979 -0.9441 1965146 CMLD1_000110 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F06 compound treatment 448366.0 80.8 0.0 444720.0 -46500.0 -0.26 -0.1868 -0.7058 1965147 CMLD1_000111 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F07 compound treatment 430173.0 -18100.0 -0.11 456882.0 -34400.0 -0.2 -0.2145 -0.9606 1965148 CMLD1_000112 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F08 compound treatment 284839.0 -163000.0 -0.97 447271.0 -44000.0 -0.25 -0.8647 -0.8609 1965149 CMLD1_000113 CCCCCC1=C2CNC(C)(C=C2C(C)C1=O)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F09 compound treatment 424982.0 -23300.0 -0.14 216184.0 -275000.0 -1.56 -1.2042 -0.7668 1965150 CMLD1_000114 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F10 compound treatment 175228.0 -273000.0 -1.63 108981.0 -382000.0 -2.17 -2.6863 -0.9897 1965151 CMLD1_000115 CCCCCC1=C2CNC(Cc3ccccc3)(C=C2C(C)C1=O)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F11 compound treatment 246204.0 -202000.0 -1.2 452947.0 -38300.0 -0.22 -1.0045 -0.8218 1965152 CMLD1_000116 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F12 compound treatment 91825.0 -356000.0 -2.12 183911.0 -307000.0 -1.75 -2.736 -0.9954 1965153 CMLD1_000117 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F13 compound treatment 81082.0 -367000.0 -2.19 238113.0 -253000.0 -1.44 -2.5632 -0.9795 1965154 CMLD1_000118 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F14 compound treatment 201941.0 -246000.0 -1.47 178766.0 -312000.0 -1.78 -2.2933 -0.9954 1965155 CMLD1_000119 C[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F15 compound treatment 250982.0 -197000.0 -1.17 382259.0 -109000.0 -0.62 -1.2686 -0.9554 1965156 CMLD1_000120 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F16 compound treatment 188398.0 -260000.0 -1.55 392566.0 -98700.0 -0.56 -1.4906 -0.9059 1965157 CMLD1_000121 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(cc5)C(F)(F)F)C=C21)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F17 compound treatment 157789.0 -290000.0 -1.73 127856.0 -363000.0 -2.07 -2.6838 -0.9961 1965158 CMLD1_000122 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F18 compound treatment 395596.0 -52700.0 -0.31 481651.0 -9610.0 -0.05 -0.2604 -0.818 1965150 CMLD1_000123 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F19 compound treatment 407070.0 -41200.0 -0.25 140963.0 -350000.0 -1.99 -1.582 -0.7882 1965159 CMLD1_000124 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F20 compound treatment 414423.0 -33900.0 -0.2 182804.0 -308000.0 -1.75 -1.3829 -0.7832 1965160 CMLD1_000125 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F21 compound treatment 38624.0 -410000.0 -2.44 55130.0 -436000.0 -2.48 -3.4777 -1.0 1965161 CMLD1_000126 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F22 mock treatment 446094.0 -2190.0 -0.01 487097.0 -4170.0 -0.02 -0.026 -0.9605 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F23 mock treatment 150312.0 -298000.0 -1.77 498310.0 7050.0 0.04 -1.2256 -0.6909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 F24 mock treatment 460141.0 11900.0 0.07 145781.0 -345000.0 -1.96 -1.3393 -0.6813 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G01 compound treatment 518108.0 69800.0 0.42 537625.0 46400.0 0.26 0.4803 0.9759 1965162 CMLD1_000127 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G02 compound treatment 244879.0 -203000.0 -1.21 230659.0 -261000.0 -1.48 -1.9039 -0.995 1965163 CMLD1_000128 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G03 compound treatment 209393.0 -239000.0 -1.42 106584.0 -385000.0 -2.19 -2.5522 -0.9782 1965164 CMLD1_000129 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccccc1)c2ccc(cc2)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G04 compound treatment 270891.0 -177000.0 -1.06 246632.0 -245000.0 -1.39 -1.7302 -0.9907 1965165 CMLD1_000130 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G05 compound treatment 135178.0 -313000.0 -1.86 115067.0 -376000.0 -2.14 -2.8304 -0.9976 1965166 CMLD1_000131 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G06 compound treatment 231245.0 -217000.0 -1.29 221352.0 -270000.0 -1.53 -1.9987 -0.9963 1965167 CMLD1_000132 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G07 compound treatment 347591.0 -101000.0 -0.6 399047.0 -92200.0 -0.52 -0.7946 -0.9978 1965168 CMLD1_000133 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G08 compound treatment 347770.0 -101000.0 -0.6 206034.0 -285000.0 -1.62 -1.5699 -0.9081 1965169 CMLD1_000134 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccccc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G09 compound treatment 416110.0 -32200.0 -0.19 250333.0 -241000.0 -1.37 -1.1042 -0.7982 1965170 CMLD1_000135 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G10 compound treatment 340960.0 -107000.0 -0.64 353928.0 -137000.0 -0.78 -1.0039 -0.995 1965171 CMLD1_000136 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)c(F)c(F)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G11 compound treatment 297765.0 -151000.0 -0.9 342717.0 -149000.0 -0.84 -1.2308 -0.9996 1965172 CMLD1_000137 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G12 compound treatment 195177.0 -253000.0 -1.51 194490.0 -297000.0 -1.69 -2.2585 -0.9984 1965173 CMLD1_000138 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G13 compound treatment 220416.0 -228000.0 -1.36 288452.0 -203000.0 -1.15 -1.7745 -0.9968 1965174 CMLD1_000139 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G14 compound treatment 446144.0 -2140.0 -0.01 415419.0 -75800.0 -0.43 -0.314 -0.7277 1965175 CMLD1_000140 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G15 compound treatment 317772.0 -131000.0 -0.78 328273.0 -163000.0 -0.93 -1.2046 -0.9961 1965176 CMLD1_000141 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G16 compound treatment 348857.0 -99400.0 -0.59 339337.0 -152000.0 -0.86 -1.0293 -0.983 1965177 CMLD1_000142 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G17 compound treatment 415618.0 -32700.0 -0.19 152283.0 -339000.0 -1.93 -1.5006 -0.7745 1965178 CMLD1_000143 CC(=CC1CCCCC1)[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G18 compound treatment 472320.0 24000.0 0.14 208307.0 -283000.0 -1.61 -1.0367 -0.6417 1965179 CMLD1_000144 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G19 compound treatment 138524.0 -310000.0 -1.84 396397.0 -94900.0 -0.54 -1.685 -0.8772 1965180 CMLD1_000145 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G20 compound treatment 437619.0 -10700.0 -0.06 441578.0 -49700.0 -0.28 -0.2447 -0.8449 1965181 CMLD1_000146 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G21 compound treatment 224168.0 -224000.0 -1.33 76163.0 -415000.0 -2.36 -2.6123 -0.9635 1965182 CMLD1_000147 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G22 mock treatment 440972.0 -7310.0 -0.04 457709.0 -33600.0 -0.19 -0.1657 -0.8467 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G23 mock treatment 169886.0 -278000.0 -1.66 422241.0 -69000.0 -0.39 -1.4491 -0.8511 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 G24 mock treatment 177448.0 -271000.0 -1.61 462475.0 -28800.0 -0.16 -1.2555 -0.7749 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H01 compound treatment 492307.0 44000.0 0.26 510520.0 19300.0 0.11 0.2627 0.9251 1965183 CMLD1_000148 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H02 compound treatment 347267.0 -101000.0 -0.6 80478.0 -411000.0 -2.34 -2.0769 -0.861 1965184 CMLD1_000149 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H03 compound treatment 432658.0 -15600.0 -0.09 113347.0 -378000.0 -2.15 -1.5854 -0.737 1965185 CMLD1_000150 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H04 compound treatment 69584.0 -379000.0 -2.25 70524.0 -421000.0 -2.39 -3.2855 -0.9996 1965186 CMLD1_000151 CCCC[C@H]1C[C@@H]1[C@@H]2N(C[C@](O)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H05 compound treatment 340427.0 -108000.0 -0.64 103171.0 -388000.0 -2.21 -2.0145 -0.8765 1965187 CMLD1_000152 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H06 compound treatment 413650.0 -34600.0 -0.21 391944.0 -99300.0 -0.56 -0.5451 -0.9067 1965147 CMLD1_000153 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H07 compound treatment 541338.0 93100.0 0.55 229254.0 -262000.0 -1.49 -0.662 -0.4165 1965188 CMLD1_000154 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H08 compound treatment 336700.0 -112000.0 -0.66 498633.0 7370.0 0.04 -0.4399 -0.6612 1965189 CMLD1_000155 CCCC1(NCC2=C(C)C(=O)C(C)C2=C1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H09 compound treatment 348282.0 -100000.0 -0.6 531204.0 39900.0 0.23 -0.2602 -0.4085 1965190 CMLD1_000156 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H10 compound treatment 559211.0 111000.0 0.66 140075.0 -351000.0 -2.0 -0.9454 -0.4494 1965191 CMLD1_000157 COC(=O)C1(CC(C)C)NCC2=C(C)C(=O)C(C)C2=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H11 compound treatment 460945.0 12700.0 0.08 167165.0 -324000.0 -1.84 -1.25 -0.6776 1965192 CMLD1_000158 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H12 compound treatment 354457.0 -93800.0 -0.56 247026.0 -244000.0 -1.39 -1.377 -0.9198 1965193 CMLD1_000159 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H13 compound treatment 409659.0 -38600.0 -0.23 259523.0 -232000.0 -1.32 -1.0944 -0.8181 1965194 CMLD1_000160 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H14 compound treatment 145774.0 -303000.0 -1.8 162261.0 -329000.0 -1.87 -2.596 -0.9998 1965195 CMLD1_000161 C[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H15 compound treatment 296420.0 -152000.0 -0.9 283697.0 -208000.0 -1.18 -1.4737 -0.9913 1965196 CMLD1_000162 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H16 compound treatment 141615.0 -307000.0 -1.83 528398.0 37100.0 0.21 -1.1412 -0.6211 1965197 CMLD1_000163 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(cc6)C(F)(F)F)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H17 compound treatment 537721.0 89400.0 0.53 466643.0 -24600.0 -0.14 0.2774 0.504 1965198 CMLD1_000164 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H18 compound treatment 377808.0 -70500.0 -0.42 393278.0 -98000.0 -0.56 -0.6906 -0.9902 1965199 CMLD1_000165 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H19 compound treatment 101680.0 -347000.0 -2.06 449725.0 -41500.0 -0.24 -1.6256 -0.783 1965200 CMLD1_000166 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H20 compound treatment 382475.0 -65800.0 -0.39 390079.0 -101000.0 -0.58 -0.6838 -0.9824 1965201 CMLD1_000167 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H21 compound treatment 442779.0 -5510.0 -0.03 167625.0 -324000.0 -1.84 -1.3246 -0.7196 1965202 CMLD1_000168 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H22 mock treatment 187080.0 -261000.0 -1.55 259258.0 -232000.0 -1.32 -2.0321 -0.9967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H23 mock treatment 111715.0 -337000.0 -2.0 532986.0 41700.0 0.24 -1.2486 -0.619 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 H24 mock treatment 492681.0 44400.0 0.26 447184.0 -44100.0 -0.25 0.0096 0.0263 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I01 compound treatment 464490.0 16200.0 0.1 472323.0 -18900.0 -0.11 -0.008 -0.0551 1965203 CMLD1_000169 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I02 compound treatment 322599.0 -126000.0 -0.75 281715.0 -210000.0 -1.19 -1.3715 -0.9748 1965204 CMLD1_000170 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I03 compound treatment 262688.0 -186000.0 -1.1 269018.0 -222000.0 -1.26 -1.6747 -0.9977 1965205 CMLD1_000171 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I04 compound treatment 335165.0 -113000.0 -0.67 388479.0 -103000.0 -0.58 -0.8893 -0.9975 1965206 CMLD1_000172 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I05 compound treatment 64335.0 -384000.0 -2.29 83307.0 -408000.0 -2.32 -3.2562 -1.0 1965207 CMLD1_000173 CCCC=C(CCC)[C@@H](NC(=O)c1ccco1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I06 compound treatment 379269.0 -69000.0 -0.41 444295.0 -47000.0 -0.27 -0.4793 -0.9783 1965208 CMLD1_000174 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I07 compound treatment 299210.0 -149000.0 -0.89 404145.0 -87100.0 -0.5 -0.9777 -0.9621 1965209 CMLD1_000175 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I08 compound treatment 155830.0 -292000.0 -1.74 368797.0 -122000.0 -0.7 -1.7232 -0.9192 1965210 CMLD1_000176 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I09 compound treatment 185659.0 -263000.0 -1.56 406544.0 -84700.0 -0.48 -1.4459 -0.884 1965211 CMLD1_000177 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I10 compound treatment 80571.0 -368000.0 -2.19 396057.0 -95200.0 -0.54 -1.9303 -0.8562 1965212 CMLD1_000178 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I11 compound treatment 26162.0 -422000.0 -2.51 73014.0 -418000.0 -2.38 -3.4583 -0.9996 1965213 CMLD1_000179 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I12 compound treatment 303482.0 -145000.0 -0.86 289665.0 -202000.0 -1.15 -1.42 -0.9901 1965214 CMLD1_000180 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I13 compound treatment 282625.0 -166000.0 -0.99 309381.0 -182000.0 -1.03 -1.4285 -0.9997 1965215 CMLD1_000181 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I14 compound treatment 368118.0 -80200.0 -0.48 354808.0 -136000.0 -0.78 -0.8861 -0.9727 1965216 CMLD1_000182 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I15 compound treatment 373284.0 -75000.0 -0.45 370176.0 -121000.0 -0.69 -0.8025 -0.978 1965217 CMLD1_000183 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I16 compound treatment 292056.0 -156000.0 -0.93 302003.0 -189000.0 -1.08 -1.4185 -0.9973 1965218 CMLD1_000184 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I17 compound treatment 341596.0 -107000.0 -0.63 396235.0 -95000.0 -0.54 -0.8311 -0.9968 1965219 CMLD1_000185 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccccc2)[C@]3(C)C[C@H]3C4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I18 compound treatment 413645.0 -34600.0 -0.21 471564.0 -19700.0 -0.11 -0.225 -0.9589 1965220 CMLD1_000186 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I19 compound treatment 394879.0 -53400.0 -0.32 398057.0 -93200.0 -0.53 -0.5995 -0.9701 1965221 CMLD1_000187 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccccc3C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I20 compound treatment 395786.0 -52500.0 -0.31 399743.0 -91500.0 -0.52 -0.5889 -0.9702 1965222 CMLD1_000188 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I21 compound treatment 147789.0 -300000.0 -1.79 256705.0 -235000.0 -1.33 -2.2078 -0.9896 1965223 CMLD1_000189 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CC6CC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I22 mock treatment 525021.0 76700.0 0.46 498604.0 7340.0 0.04 0.3524 0.7685 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I23 mock treatment 565861.0 118000.0 0.7 517241.0 26000.0 0.15 0.5993 0.8379 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 I24 mock treatment 487590.0 39300.0 0.23 497777.0 6510.0 0.04 0.1916 0.809 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J01 compound treatment 466372.0 18100.0 0.11 495056.0 3790.0 0.02 0.0914 0.8323 1965224 CMLD1_000190 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J02 compound treatment 120683.0 -328000.0 -1.95 89329.0 -402000.0 -2.29 -2.9949 -0.9969 1965225 CMLD1_000191 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J03 compound treatment 420612.0 -27700.0 -0.16 437814.0 -53400.0 -0.3 -0.3314 -0.9586 1965226 CMLD1_000192 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J04 compound treatment 71779.0 -377000.0 -2.24 82050.0 -409000.0 -2.33 -3.2299 -0.9998 1965227 CMLD1_000193 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@](CO)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J05 compound treatment 261555.0 -187000.0 -1.11 304296.0 -187000.0 -1.06 -1.5376 -0.9998 1965228 CMLD1_000194 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J06 compound treatment 424555.0 -23700.0 -0.14 470484.0 -20800.0 -0.12 -0.1834 -0.9961 1965229 CMLD1_000195 OC1(CN(CC2(CC2)C1)P(=O)(c3ccccc3)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J07 compound treatment 413933.0 -34400.0 -0.2 538907.0 47600.0 0.27 0.047 0.1385 1965230 CMLD1_000196 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J08 compound treatment 465310.0 17000.0 0.1 551322.0 60100.0 0.34 0.3132 0.879 1965231 CMLD1_000197 CCCC1(NCC2=C(C(C)C)C(=O)C(C)C2=C1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J09 compound treatment 244485.0 -204000.0 -1.21 299186.0 -192000.0 -1.09 -1.63 -0.9986 1965232 CMLD1_000198 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J10 compound treatment 485432.0 37100.0 0.22 455168.0 -36100.0 -0.21 0.0112 0.0371 1965233 CMLD1_000199 COC(=O)C1(CC(C)C)NCC2=C(C(C)C)C(=O)C(C)C2=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J11 compound treatment 458908.0 10600.0 0.06 466945.0 -24300.0 -0.14 -0.0531 -0.3491 1965234 CMLD1_000200 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J12 compound treatment 90987.0 -357000.0 -2.13 191437.0 -300000.0 -1.71 -2.7093 -0.994 1965235 CMLD1_000201 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cccc(Cl)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J13 compound treatment 485005.0 36700.0 0.22 486769.0 -4490.0 -0.03 0.1365 0.6202 1965236 CMLD1_000202 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J14 compound treatment 307167.0 -141000.0 -0.84 436651.0 -54600.0 -0.31 -0.8135 -0.9085 1965237 CMLD1_000203 CC[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J15 compound treatment 97157.0 -351000.0 -2.09 121474.0 -370000.0 -2.1 -2.9646 -1.0 1965238 CMLD1_000204 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J16 compound treatment 138338.0 -310000.0 -1.84 302319.0 -189000.0 -1.07 -2.0641 -0.9669 1965239 CMLD1_000205 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J17 compound treatment 370709.0 -77600.0 -0.46 419811.0 -71500.0 -0.41 -0.6138 -0.998 1965240 CMLD1_000206 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J18 compound treatment 282198.0 -166000.0 -0.99 481912.0 -9350.0 -0.05 -0.7365 -0.7441 1965241 CMLD1_000207 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J19 compound treatment 463237.0 15000.0 0.09 446215.0 -45000.0 -0.26 -0.1182 -0.4359 1965242 CMLD1_000208 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J20 compound treatment 359732.0 -88600.0 -0.53 493503.0 2240.0 0.01 -0.3636 -0.6898 1965243 CMLD1_000209 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J21 compound treatment 440935.0 -7350.0 -0.04 435870.0 -55400.0 -0.32 -0.2537 -0.7976 1965244 CMLD1_000210 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J22 mock treatment 476010.0 27700.0 0.17 499878.0 8620.0 0.05 0.1513 0.8791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J23 mock treatment 519981.0 71700.0 0.43 518785.0 27500.0 0.16 0.4124 0.9074 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 J24 mock treatment 524920.0 76600.0 0.46 501605.0 10300.0 0.06 0.3641 0.7917 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K01 compound treatment 538830.0 90500.0 0.54 511570.0 20300.0 0.12 0.4627 0.8396 1965245 CMLD1_000211 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K02 compound treatment 481155.0 32900.0 0.2 398641.0 -92600.0 -0.53 -0.2341 -0.4167 1965246 CMLD1_000212 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K03 compound treatment 248358.0 -200000.0 -1.19 215558.0 -276000.0 -1.57 -1.95 -0.9907 1965247 CMLD1_000213 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K04 compound treatment 216682.0 -232000.0 -1.38 208602.0 -283000.0 -1.61 -2.1113 -0.9971 1965248 CMLD1_000214 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K05 compound treatment 391047.0 -57200.0 -0.34 378328.0 -113000.0 -0.64 -0.695 -0.956 1965249 CMLD1_000215 CCCC=C(CCC)[C@@H](NC(=O)C(C)(C)C)c1ccc(cc1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K06 compound treatment 323507.0 -125000.0 -0.74 445129.0 -46100.0 -0.26 -0.7106 -0.9023 1965250 CMLD1_000216 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K07 compound treatment 291664.0 -157000.0 -0.93 81100.0 -410000.0 -2.33 -2.3084 -0.919 1965251 CMLD1_000217 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K08 compound treatment 331513.0 -117000.0 -0.69 122316.0 -369000.0 -2.1 -1.975 -0.8936 1965252 CMLD1_000218 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K09 compound treatment 181957.0 -266000.0 -1.59 167938.0 -323000.0 -1.84 -2.4209 -0.9973 1965253 CMLD1_000219 CCCC=C(CCC)[C@@H](NC(=O)Cc1ccccc1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K10 compound treatment 321585.0 -127000.0 -0.75 473595.0 -17700.0 -0.1 -0.6042 -0.7943 1965254 CMLD1_000220 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K11 compound treatment 379003.0 -69300.0 -0.41 79491.0 -412000.0 -2.34 -1.9474 -0.819 1965255 CMLD1_000221 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K12 compound treatment 395918.0 -52400.0 -0.31 167437.0 -324000.0 -1.84 -1.5225 -0.8152 1965256 CMLD1_000222 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K13 compound treatment 65857.0 -382000.0 -2.28 78235.0 -413000.0 -2.35 -3.2702 -0.9999 1965257 CMLD1_000223 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K14 compound treatment 450527.0 2240.0 0.01 438907.0 -52400.0 -0.3 -0.2011 -0.6747 1965258 CMLD1_000224 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K15 compound treatment 317305.0 -131000.0 -0.78 345856.0 -145000.0 -0.83 -1.1359 -0.9996 1965259 CMLD1_000225 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K16 compound treatment 554204.0 106000.0 0.63 532233.0 41000.0 0.23 0.6105 0.9084 1965260 CMLD1_000226 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K17 compound treatment 143965.0 -304000.0 -1.81 151774.0 -339000.0 -1.93 -2.6458 -0.9995 1965261 CMLD1_000227 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccco2)[C@]3(C)C[C@H]3C4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K18 compound treatment 501334.0 53000.0 0.32 551233.0 60000.0 0.34 0.4644 0.9993 1965262 CMLD1_000228 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K19 compound treatment 209365.0 -239000.0 -1.42 230561.0 -261000.0 -1.48 -2.0538 -0.9998 1965263 CMLD1_000229 CCCC[C@@H]1C[C@H]1[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K20 compound treatment 62054.0 -386000.0 -2.3 61861.0 -429000.0 -2.44 -3.3521 -0.9995 1965264 CMLD1_000230 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K21 compound treatment 146634.0 -302000.0 -1.8 414027.0 -77200.0 -0.44 -1.58 -0.8549 1965265 CMLD1_000231 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K22 mock treatment 404064.0 -44200.0 -0.26 489226.0 -2040.0 -0.01 -0.1943 -0.7375 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K23 mock treatment 478377.0 30100.0 0.18 500343.0 9080.0 0.05 0.1631 0.8753 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 K24 mock treatment 514989.0 66700.0 0.4 463971.0 -27300.0 -0.16 0.171 0.4011 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L01 compound treatment 526744.0 78500.0 0.47 486736.0 -4530.0 -0.03 0.312 0.6671 1965266 CMLD1_000232 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L02 compound treatment 293351.0 -155000.0 -0.92 131688.0 -360000.0 -2.04 -2.0979 -0.9353 1965267 CMLD1_000233 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L03 compound treatment 495181.0 46900.0 0.28 445621.0 -45600.0 -0.26 0.0138 0.0363 1965268 CMLD1_000234 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L04 compound treatment 379322.0 -69000.0 -0.41 373965.0 -117000.0 -0.67 -0.7619 -0.9728 1965269 CMLD1_000235 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@H](CC32CC3)c4cccc(OC)c4)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L05 compound treatment 359750.0 -88500.0 -0.53 441201.0 -50100.0 -0.28 -0.5739 -0.9582 1965270 CMLD1_000236 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7cc8ccccc8[nH]7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L06 compound treatment 463086.0 14800.0 0.09 436257.0 -55000.0 -0.31 -0.1589 -0.489 1965271 CMLD1_000237 C=C(CC1(CNP(=O)(c2ccccc2)c3ccccc3)CC1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L07 compound treatment 433226.0 -15100.0 -0.09 516823.0 25600.0 0.15 0.0394 0.2308 1965272 CMLD1_000238 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L08 compound treatment 433486.0 -14800.0 -0.09 540497.0 49200.0 0.28 0.1357 0.4623 1965273 CMLD1_000239 CCCC1(NCC2=C(C(=O)C(C)C2=C1)c3ccccc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L09 compound treatment 440161.0 -8120.0 -0.05 527001.0 35700.0 0.2 0.1095 0.5243 1965274 CMLD1_000240 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L10 compound treatment 474115.0 25800.0 0.15 613753.0 122000.0 0.7 0.6013 0.8429 1965275 CMLD1_000241 COC(=O)C1(CC(C)C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L11 compound treatment 468342.0 20100.0 0.12 534510.0 43200.0 0.25 0.2583 0.9449 1965276 CMLD1_000242 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L12 compound treatment 238475.0 -210000.0 -1.25 289141.0 -202000.0 -1.15 -1.6957 -0.9991 1965277 CMLD1_000243 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cc(F)cc(F)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L13 compound treatment 488123.0 39800.0 0.24 485261.0 -6000.0 -0.03 0.1435 0.5991 1965278 CMLD1_000244 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L14 compound treatment 109134.0 -339000.0 -2.02 125697.0 -366000.0 -2.08 -2.8972 -0.9999 1965279 CMLD1_000245 CC[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L15 compound treatment 483475.0 35200.0 0.21 546553.0 55300.0 0.31 0.3704 0.9805 1965280 CMLD1_000246 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L16 compound treatment 512010.0 63700.0 0.38 547031.0 55800.0 0.32 0.4924 0.996 1965281 CMLD1_000247 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccccc6)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L17 compound treatment 179293.0 -269000.0 -1.6 537148.0 45900.0 0.26 -0.9475 -0.5841 1965282 CMLD1_000248 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSC(=N)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L18 compound treatment 489612.0 41300.0 0.25 551483.0 60200.0 0.34 0.4161 0.9868 1965079 CMLD1_000249 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L19 compound treatment 308976.0 -139000.0 -0.83 367596.0 -124000.0 -0.7 -1.0835 -0.9966 1965283 CMLD1_000250 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L20 compound treatment 500506.0 52200.0 0.31 529505.0 38200.0 0.22 0.3735 0.9848 1965284 CMLD1_000251 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L21 compound treatment 447628.0 -657.0 0.0 504800.0 13500.0 0.08 0.0517 0.6703 1965285 CMLD1_000252 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L22 mock treatment 498138.0 49900.0 0.3 456170.0 -35100.0 -0.2 0.0687 0.1921 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L23 mock treatment 438126.0 -10200.0 -0.06 582324.0 91100.0 0.52 0.3234 0.6203 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 L24 mock treatment 525138.0 76900.0 0.46 561675.0 70400.0 0.4 0.6066 0.9978 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M01 compound treatment 505026.0 56700.0 0.34 528368.0 37100.0 0.21 0.388 0.9744 1965286 CMLD1_000253 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M02 compound treatment 378482.0 -69800.0 -0.42 423909.0 -67400.0 -0.38 -0.5646 -0.9992 1965287 CMLD1_000254 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M03 compound treatment 413219.0 -35100.0 -0.21 403636.0 -87600.0 -0.5 -0.4999 -0.9254 1965288 CMLD1_000255 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M04 compound treatment 153732.0 -295000.0 -1.75 123025.0 -368000.0 -2.09 -2.7203 -0.9961 1965289 CMLD1_000256 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(C)onc7c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M05 compound treatment 454467.0 6180.0 0.04 456073.0 -35200.0 -0.2 -0.1155 -0.5676 1965290 CMLD1_000257 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M06 compound treatment 406742.0 -41500.0 -0.25 499093.0 7830.0 0.04 -0.1433 -0.5706 1965090 CMLD1_000258 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M07 compound treatment 393302.0 -55000.0 -0.33 424680.0 -66600.0 -0.38 -0.4991 -0.9974 1965291 CMLD1_000259 CCCCC=C[C@@H](NC(=O)c1ccco1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M08 compound treatment 279676.0 -169000.0 -1.0 360029.0 -131000.0 -0.75 -1.2373 -0.9894 1965292 CMLD1_000260 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M09 compound treatment 352044.0 -96200.0 -0.57 436574.0 -54700.0 -0.31 -0.6249 -0.9588 1965293 CMLD1_000261 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)OCc2ccccc2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M10 compound treatment 336712.0 -112000.0 -0.66 399170.0 -92100.0 -0.52 -0.8398 -0.9931 1965294 CMLD1_000262 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCCNc6ccc(cc6Cl)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M11 compound treatment 202458.0 -246000.0 -1.46 237604.0 -254000.0 -1.44 -2.0545 -1.0 1965295 CMLD1_000263 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M12 compound treatment 250593.0 -198000.0 -1.18 299171.0 -192000.0 -1.09 -1.6044 -0.9993 1965296 CMLD1_000264 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M13 compound treatment 152721.0 -296000.0 -1.76 166740.0 -325000.0 -1.85 -2.5488 -0.9997 1965297 CMLD1_000265 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M14 compound treatment 298102.0 -150000.0 -0.89 366913.0 -124000.0 -0.71 -1.132 -0.9933 1965298 CMLD1_000266 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M15 compound treatment 495517.0 47200.0 0.28 504374.0 13100.0 0.07 0.2515 0.8648 1965299 CMLD1_000267 CCCC[C@@H]1C[C@H]1[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M16 compound treatment 461675.0 13400.0 0.08 548517.0 57300.0 0.33 0.2866 0.8549 1965300 CMLD1_000268 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(O)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M17 compound treatment 430881.0 -17400.0 -0.1 528896.0 37600.0 0.21 0.0781 0.3284 1965301 CMLD1_000269 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(Cl)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M18 compound treatment 178570.0 -270000.0 -1.61 569197.0 77900.0 0.44 -0.8217 -0.4934 1965302 CMLD1_000270 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M19 compound treatment 258282.0 -190000.0 -1.13 334513.0 -157000.0 -0.89 -1.4299 -0.9931 1965303 CMLD1_000271 CCCC=C(CCC)[C@@H](NC(=O)Oc1ccc(F)cc1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M20 compound treatment 498013.0 49700.0 0.3 403316.0 -87900.0 -0.5 -0.1444 -0.2484 1965304 CMLD1_000272 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M21 mock treatment 142987.0 -305000.0 -1.82 438203.0 -53100.0 -0.3 -1.4981 -0.8134 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M22 mock treatment 357206.0 -91100.0 -0.54 450180.0 -41100.0 -0.23 -0.5485 -0.9292 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M23 mock treatment 461387.0 13100.0 0.08 575440.0 84200.0 0.48 0.3936 0.8116 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 M24 mock treatment 474800.0 26500.0 0.16 503373.0 12100.0 0.07 0.1603 0.9309 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N01 compound treatment 542649.0 94400.0 0.56 471064.0 -20200.0 -0.11 0.3159 0.5511 1965305 CMLD1_000273 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N02 compound treatment 496443.0 48200.0 0.29 517749.0 26500.0 0.15 0.3092 0.9549 1965306 CMLD1_000274 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N03 compound treatment 167927.0 -280000.0 -1.67 307470.0 -184000.0 -1.05 -1.9189 -0.9746 1965307 CMLD1_000275 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N04 compound treatment 73731.0 -375000.0 -2.23 100403.0 -391000.0 -2.22 -3.1479 -1.0 1965308 CMLD1_000276 COC(=O)c1ccc(C#CC(NP(=O)(c2ccccc2)c3ccccc3)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N05 compound treatment 166055.0 -282000.0 -1.68 392422.0 -98800.0 -0.56 -1.5852 -0.895 1965309 CMLD1_000277 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N06 compound treatment 396151.0 -52100.0 -0.31 574756.0 83500.0 0.47 0.1163 0.2051 1965310 CMLD1_000278 O=P(NCC1(CC2(CO2)c3ccccc3)CC1)(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N07 compound treatment 197159.0 -251000.0 -1.49 492458.0 1200.0 0.01 -1.052 -0.7039 1965311 CMLD1_000279 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N08 compound treatment 374781.0 -73500.0 -0.44 588811.0 97500.0 0.55 0.0829 0.1174 1965312 CMLD1_000280 CCCCCC1=C2CNC(CCC)(C=C2C(C)C1=O)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N09 compound treatment 547178.0 98900.0 0.59 598453.0 107000.0 0.61 0.8472 0.9998 1965313 CMLD1_000281 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CCOCC7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N10 compound treatment 481634.0 33300.0 0.2 399856.0 -91400.0 -0.52 -0.2272 -0.4084 1965314 CMLD1_000282 CCCCCC1=C2CNC(CC(C)C)(C=C2C(C)C1=O)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N11 compound treatment 522610.0 74300.0 0.44 552630.0 61400.0 0.35 0.5595 0.9931 1965315 CMLD1_000283 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N12 compound treatment 517739.0 69500.0 0.41 599614.0 108000.0 0.62 0.728 0.9811 1965316 CMLD1_000284 COC1OC[C@]2(C)[C@@H]3[C@H]1CCC4C(CO)C(CO)[C@@H](C)C(=C43)CN2C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N13 compound treatment 595225.0 147000.0 0.87 555113.0 63900.0 0.36 0.8751 0.9242 1965317 CMLD1_000285 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N14 compound treatment 456106.0 7820.0 0.05 499505.0 8240.0 0.05 0.0661 1.0 1965318 CMLD1_000286 CC[C@@H]1C(COC)C(COC)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N15 compound treatment 158143.0 -290000.0 -1.73 551398.0 60100.0 0.34 -0.9792 -0.5563 1965319 CMLD1_000287 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N16 compound treatment 457526.0 9240.0 0.05 478639.0 -12600.0 -0.07 -0.0119 -0.1313 1965320 CMLD1_000288 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccccc5)C=C21)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N17 compound treatment 521814.0 73500.0 0.44 649234.0 158000.0 0.9 0.9447 0.9454 1965321 CMLD1_000289 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N18 compound treatment 534731.0 86400.0 0.51 483924.0 -7340.0 -0.04 0.3343 0.6476 1965322 CMLD1_000290 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N19 compound treatment 263408.0 -185000.0 -1.1 454311.0 -37000.0 -0.21 -0.9266 -0.8272 1965323 CMLD1_000291 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(O)cc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N20 compound treatment 409774.0 -38500.0 -0.23 467174.0 -24100.0 -0.14 -0.2589 -0.9697 1965324 CMLD1_000292 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N21 mock treatment 490515.0 42200.0 0.25 519975.0 28700.0 0.16 0.2932 0.9782 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N22 mock treatment 518702.0 70400.0 0.42 456298.0 -35000.0 -0.2 0.1557 0.3357 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N23 mock treatment 463710.0 15400.0 0.09 527672.0 36400.0 0.21 0.2113 0.933 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 N24 mock treatment 452315.0 4030.0 0.02 573334.0 82100.0 0.47 0.347 0.7425 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O01 compound treatment 571506.0 123000.0 0.73 549558.0 58300.0 0.33 0.753 0.9356 1965325 CMLD1_000293 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccc(cc1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O02 compound treatment 201653.0 -247000.0 -1.47 184104.0 -307000.0 -1.75 -2.273 -0.9963 1965326 CMLD1_000294 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O03 compound treatment 359265.0 -89000.0 -0.53 413638.0 -77600.0 -0.44 -0.6868 -0.9959 1965327 CMLD1_000295 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O04 compound treatment 317123.0 -131000.0 -0.78 314193.0 -177000.0 -1.01 -1.264 -0.9921 1965268 CMLD1_000296 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O05 compound treatment 63969.0 -384000.0 -2.29 64525.0 -427000.0 -2.43 -3.3333 -0.9996 1965328 CMLD1_000297 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O06 compound treatment 360850.0 -87400.0 -0.52 465833.0 -25400.0 -0.14 -0.4702 -0.8706 1965329 CMLD1_000298 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O07 compound treatment 263516.0 -185000.0 -1.1 270917.0 -220000.0 -1.25 -1.6636 -0.9979 1965330 CMLD1_000299 CCCCC=C[C@@H](NC(=O)c1cccs1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O08 compound treatment 510756.0 62500.0 0.37 634901.0 144000.0 0.82 0.8405 0.9365 1965331 CMLD1_000300 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O09 compound treatment 345061.0 -103000.0 -0.61 108205.0 -383000.0 -2.18 -1.9747 -0.8725 1965332 CMLD1_000301 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O10 compound treatment 323552.0 -125000.0 -0.74 64139.0 -427000.0 -2.43 -2.2424 -0.8829 1965333 CMLD1_000302 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O11 compound treatment 424633.0 -23700.0 -0.14 500560.0 9300.0 0.05 -0.0621 -0.4133 1965334 CMLD1_000303 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O12 compound treatment 236350.0 -212000.0 -1.26 300383.0 -191000.0 -1.09 -1.6594 -0.9972 1965335 CMLD1_000304 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O13 compound treatment 418863.0 -29400.0 -0.18 428087.0 -63200.0 -0.36 -0.3779 -0.9454 1965336 CMLD1_000305 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O14 compound treatment 65498.0 -383000.0 -2.28 70846.0 -420000.0 -2.39 -3.3014 -0.9997 1965337 CMLD1_000306 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O15 compound treatment 417005.0 -31300.0 -0.19 587534.0 96300.0 0.55 0.2555 0.4418 1965338 CMLD1_000307 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O16 compound treatment 267885.0 -180000.0 -1.07 408901.0 -82400.0 -0.47 -1.0904 -0.9309 1965339 CMLD1_000308 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O17 compound treatment 254130.0 -194000.0 -1.16 296729.0 -195000.0 -1.11 -1.5993 -0.9998 1965340 CMLD1_000309 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O18 compound treatment 156449.0 -292000.0 -1.74 269972.0 -221000.0 -1.26 -2.118 -0.9875 1965341 CMLD1_000310 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O19 compound treatment 193941.0 -254000.0 -1.51 68741.0 -423000.0 -2.4 -2.7694 -0.9752 1965342 CMLD1_000311 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O20 compound treatment 139762.0 -309000.0 -1.84 188678.0 -303000.0 -1.72 -2.5151 -0.9995 1965343 CMLD1_000312 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O21 mock treatment 432418.0 -15900.0 -0.09 348425.0 -143000.0 -0.81 -0.6411 -0.784 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O22 mock treatment 198953.0 -249000.0 -1.48 515878.0 24600.0 0.14 -0.9503 -0.6376 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O23 mock treatment 545184.0 96900.0 0.58 565152.0 73900.0 0.42 0.7049 0.9879 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 O24 mock treatment 614854.0 167000.0 0.99 714312.0 223000.0 1.27 1.5979 0.9926 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P01 compound treatment 549764.0 101000.0 0.6 543197.0 51900.0 0.3 0.6359 0.9459 1965344 CMLD1_000313 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P02 compound treatment 438243.0 -10000.0 -0.06 427976.0 -63300.0 -0.36 -0.2967 -0.8134 1965345 CMLD1_000314 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P03 compound treatment 442252.0 -6030.0 -0.04 251956.0 -239000.0 -1.36 -0.9877 -0.7255 1965346 CMLD1_000315 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P04 compound treatment 193539.0 -255000.0 -1.52 246455.0 -245000.0 -1.39 -2.0565 -0.9991 1965347 CMLD1_000316 COC(=O)c1ccc(cc1)C23CC3(C2)C(NP(=O)(c4ccccc4)c5ccccc5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P05 compound treatment 352197.0 -96100.0 -0.57 352273.0 -139000.0 -0.79 -0.9633 -0.9874 1965348 CMLD1_000317 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P06 compound treatment 110624.0 -338000.0 -2.01 133443.0 -358000.0 -2.03 -2.8598 -1.0 1965349 CMLD1_000318 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P07 compound treatment 324835.0 -123000.0 -0.73 569248.0 78000.0 0.44 -0.2059 -0.24 1965350 CMLD1_000319 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P08 compound treatment 463969.0 15700.0 0.09 532554.0 41300.0 0.23 0.232 0.9183 1965351 CMLD1_000320 COC(=O)C1(Cc2ccccc2)NCC3=C(C)C(=O)C(C)C3=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P09 compound treatment 486082.0 37800.0 0.22 236176.0 -255000.0 -1.45 -0.8667 -0.5904 1965352 CMLD1_000321 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P10 compound treatment 143648.0 -305000.0 -1.81 104802.0 -386000.0 -2.2 -2.836 -0.9954 1965353 CMLD1_000322 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P11 compound treatment 510635.0 62300.0 0.37 618989.0 128000.0 0.73 0.776 0.9514 1965354 CMLD1_000323 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P12 compound treatment 561921.0 114000.0 0.68 621550.0 130000.0 0.74 1.0021 0.999 1965355 CMLD1_000324 CC[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OC)OC[C@]4(C)[C@H]3C2=C1CN4C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P13 compound treatment 513970.0 65700.0 0.39 592951.0 102000.0 0.58 0.6853 0.9818 1965356 CMLD1_000325 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P14 compound treatment 140408.0 -308000.0 -1.83 157554.0 -334000.0 -1.9 -2.6375 -0.9998 1965357 CMLD1_000326 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(OC)cc5)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P15 compound treatment 477862.0 29600.0 0.18 586061.0 94800.0 0.54 0.5057 0.8917 1965358 CMLD1_000327 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P16 compound treatment 264684.0 -184000.0 -1.09 373524.0 -118000.0 -0.67 -1.2461 -0.9724 1965359 CMLD1_000328 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)cc7COCOc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P17 compound treatment 58069.0 -390000.0 -2.32 64664.0 -427000.0 -2.43 -3.3576 -0.9998 1965360 CMLD1_000329 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P18 compound treatment 499824.0 51500.0 0.31 577392.0 86100.0 0.49 0.5632 0.9746 1965361 CMLD1_000330 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P19 compound treatment 470546.0 22300.0 0.13 464738.0 -26500.0 -0.15 -0.013 -0.0646 1965362 CMLD1_000331 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P20 compound treatment 461152.0 12900.0 0.08 494209.0 2950.0 0.02 0.066 0.8419 1965363 CMLD1_000332 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P21 mock treatment 494174.0 45900.0 0.27 572801.0 81500.0 0.46 0.521 0.9681 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P22 mock treatment 538219.0 89900.0 0.54 583280.0 92000.0 0.52 0.7485 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P23 mock treatment 406715.0 -41600.0 -0.25 619073.0 128000.0 0.73 0.339 0.4415 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1462 P24 mock treatment 589877.0 142000.0 0.84 667523.0 176000.0 1.0 1.3046 0.9963 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A01 compound treatment 523747.0 68400.0 0.41 533373.0 15200.0 0.09 0.3489 0.8384 2065621 ICCB6_000001 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A02 compound treatment 312197.0 -143000.0 -0.85 486199.0 -32000.0 -0.18 -0.731 -0.8392 2065622 ICCB6_000002 OCCCCCCCCCc1ccc(C=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A03 compound treatment 204698.0 -251000.0 -1.49 572132.0 53900.0 0.31 -0.8379 -0.5502 2065623 ICCB6_000003 CC1(C)OC(=O)C=C(CC(O)c2ccccc2)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A04 compound treatment 311462.0 -144000.0 -0.86 440601.0 -77600.0 -0.44 -0.9175 -0.9525 2065624 ICCB6_000004 CO[C@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc3ccccc3)[C@@H]1OCCCc4ccc(C=O)o4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A05 compound treatment 138566.0 -317000.0 -1.89 366357.0 -152000.0 -0.86 -1.9436 -0.9373 2065625 ICCB6_000005 Clc1ccccc1C(CC(=O)c2ccccc2)C(=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A06 compound treatment 234409.0 -221000.0 -1.31 547718.0 29500.0 0.17 -0.811 -0.6119 2065626 ICCB6_000006 OCCCCCCCCCCc1ccc(C=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A07 compound treatment 309453.0 -146000.0 -0.87 591932.0 73700.0 0.42 -0.3174 -0.3292 2065627 ICCB6_000007 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A08 compound treatment 334965.0 -120000.0 -0.72 517534.0 -662.0 0.0 -0.5092 -0.7108 2065628 ICCB6_000008 OC[C@H](COCCCc1ccc(C=O)o1)OCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A09 compound treatment 405418.0 -49900.0 -0.3 512867.0 -5330.0 -0.03 -0.2315 -0.7752 2065629 ICCB6_000009 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A10 compound treatment 504527.0 49200.0 0.29 489959.0 -28200.0 -0.16 0.0935 0.2799 2065630 ICCB6_000010 OCCOCCCc1ccc(C=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A11 compound treatment 459623.0 4290.0 0.03 647064.0 129000.0 0.73 0.5362 0.7313 2065631 ICCB6_000011 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A12 compound treatment 443154.0 -12200.0 -0.07 532792.0 14600.0 0.08 0.0074 0.0673 2065632 ICCB6_000012 OCc1ccc(CCc2ccc(C=O)o2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A13 compound treatment 477600.0 22300.0 0.13 674114.0 156000.0 0.89 0.7207 0.8038 2065633 ICCB6_000013 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A14 compound treatment 496116.0 40800.0 0.24 539292.0 21100.0 0.12 0.2564 0.9472 2065634 ICCB6_000014 OCCOCCOCCCc1ccc(C=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A15 compound treatment 290601.0 -165000.0 -0.98 199502.0 -319000.0 -1.81 -1.9748 -0.9584 ICCB6_000015 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A16 compound treatment 509572.0 54200.0 0.32 465715.0 -52500.0 -0.3 0.0172 0.0391 2065635 ICCB6_000016 OCC1CC2CCN1CC2CCc3ccc(C=O)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A17 compound treatment 478162.0 22800.0 0.14 501722.0 -16500.0 -0.09 0.0298 0.1807 1952805 ICCB6_000017 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A18 compound treatment 463248.0 7910.0 0.05 518734.0 538.0 0.0 0.0355 0.7515 2065636 ICCB6_000018 OCCCCNC(=O)OCCCc1ccc(C=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A19 compound treatment 399395.0 -55900.0 -0.33 473022.0 -45200.0 -0.26 -0.4171 -0.9918 1952839 ICCB6_000019 Oc1ccccc1C#CC#Cc2ccccc2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A20 compound treatment 428041.0 -27300.0 -0.16 500002.0 -18200.0 -0.1 -0.188 -0.9763 2065637 ICCB6_000020 OCCCCc1ccc(C=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A21 compound treatment 65367.0 -390000.0 -2.32 58396.0 -460000.0 -2.61 -3.49 -0.9982 1952635 ICCB6_000021 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A22 compound treatment 184586.0 -271000.0 -1.61 189324.0 -329000.0 -1.87 -2.4618 -0.9972 2065638 ICCB6_000022 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A23 mock treatment 439455.0 -15900.0 -0.09 519901.0 1710.0 0.01 -0.06 -0.6313 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 A24 mock treatment 438609.0 -16700.0 -0.1 578219.0 60000.0 0.34 0.171 0.4808 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B01 compound treatment 177018.0 -278000.0 -1.66 686170.0 168000.0 0.96 -0.4958 -0.2593 2065621 ICCB6_000023 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B02 compound treatment 120679.0 -335000.0 -1.99 146907.0 -371000.0 -2.11 -2.9013 -0.9996 2065639 ICCB6_000024 OB1OC(COCc2ccccc2)CC=C1C(=C)CCCc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B03 compound treatment 106296.0 -349000.0 -2.08 665816.0 148000.0 0.84 -0.8753 -0.3907 2065640 ICCB6_000025 CC1(C)OC(=O)C=C(CC(O)C2CCCCC2)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B04 compound treatment 507006.0 51700.0 0.31 385761.0 -132000.0 -0.75 -0.3151 -0.3874 2065641 ICCB6_000026 CC(C)C(=C)C1=CCC(COCc2ccccc2)OB1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B05 compound treatment 95996.0 -359000.0 -2.14 92826.0 -425000.0 -2.42 -3.2227 -0.9981 2065642 ICCB6_000027 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B06 compound treatment 525822.0 70500.0 0.42 576394.0 58200.0 0.33 0.5306 0.9931 2065643 ICCB6_000028 CCCC(=C)C1=CCC(COCc2ccccc2)OB1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B07 compound treatment 208988.0 -246000.0 -1.47 595934.0 77700.0 0.44 -0.7241 -0.4729 2065644 ICCB6_000029 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B08 compound treatment 537118.0 81800.0 0.49 589725.0 71500.0 0.41 0.6318 0.996 2065645 ICCB6_000030 O[C@@H]([C@H](Oc1ccccc1)C=C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B09 compound treatment 534470.0 79100.0 0.47 582631.0 64400.0 0.37 0.5921 0.9923 2065646 ICCB6_000031 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B10 compound treatment 530397.0 75100.0 0.45 590789.0 72600.0 0.41 0.6078 0.9992 2065647 ICCB6_000032 O[C@H](COCc1ccccc1)[C@H](Oc2ccccc2)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B11 compound treatment 472690.0 17400.0 0.1 601153.0 83000.0 0.47 0.4066 0.842 2065648 ICCB6_000033 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B12 compound treatment 458972.0 3630.0 0.02 458292.0 -59900.0 -0.34 -0.2256 -0.6609 2065649 ICCB6_000034 CC(C)C(=C)C(=O)CCC(COCc1ccccc1)OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B13 compound treatment 506110.0 50800.0 0.3 520158.0 1960.0 0.01 0.2216 0.7327 2065650 ICCB6_000035 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B14 compound treatment 157765.0 -298000.0 -1.77 167901.0 -350000.0 -1.99 -2.6609 -0.9983 2065651 ICCB6_000036 CCCC(=C=CC[C@@H](OC(=O)Nc1ccc(Br)cc1)c2ccccc2)CCOC(=O)Nc3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B15 compound treatment 484599.0 29300.0 0.17 511290.0 -6910.0 -0.04 0.0954 0.5342 1952458 ICCB6_000037 Fc1ccc(cc1Br)[C@@H]2C3=C(C[C@@H]4C2=CCn5n4c(=O)n(c6ccccc6)c5=O)C(=O)OC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B16 compound treatment 88235.0 -367000.0 -2.18 78551.0 -440000.0 -2.5 -3.3127 -0.9977 2065652 ICCB6_000038 CC(C)C(=C=CC[C@H](COCc1ccccc1)OC(=O)c2ccc(Br)cc2)CCOC(=O)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B17 compound treatment 70942.0 -384000.0 -2.29 65900.0 -452000.0 -2.57 -3.4364 -0.9983 1952808 ICCB6_000039 CCCCCc1cc2ccccc2o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B18 compound treatment 468012.0 12700.0 0.08 484446.0 -33700.0 -0.19 -0.0824 -0.3994 2065653 ICCB6_000040 CC1(C)OC[C@@H](C=C)[C@H](CCc2ccccc2)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B19 compound treatment 438511.0 -16800.0 -0.1 438486.0 -79700.0 -0.45 -0.3913 -0.843 1952842 ICCB6_000041 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B20 compound treatment 458693.0 3360.0 0.02 497298.0 -20900.0 -0.12 -0.0699 -0.5801 2065654 ICCB6_000042 CCC[C@@]1(CCO[Si](c2ccccc2)(c3ccccc3)C(C)(C)C)O[C@@H](Cc4ccccc4)CC=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B21 compound treatment 50919.0 -404000.0 -2.41 55519.0 -463000.0 -2.63 -3.5624 -0.999 1952636 ICCB6_000043 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B22 compound treatment 65298.0 -390000.0 -2.32 57938.0 -460000.0 -2.62 -3.4922 -0.9982 3056822 ICCB6_000044 CC(C)[Si](OC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)c4ccccc4C3=O)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B23 mock treatment 403124.0 -52200.0 -0.31 581944.0 63700.0 0.36 0.0366 0.0767 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 B24 mock treatment 509905.0 54600.0 0.32 552786.0 34600.0 0.2 0.3687 0.9711 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C01 compound treatment 480522.0 25200.0 0.15 615684.0 97500.0 0.55 0.498 0.8671 2065655 ICCB6_000045 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(C)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C02 compound treatment 175261.0 -280000.0 -1.67 441597.0 -76600.0 -0.44 -1.4867 -0.8629 2065656 ICCB6_000046 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C03 compound treatment 409660.0 -45700.0 -0.27 481987.0 -36200.0 -0.21 -0.3378 -0.9906 2065657 ICCB6_000047 COC(=O)c1cn2c(c1C(=O)OC)c(=O)n(C)c3ccccc32 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C04 compound treatment 431971.0 -23400.0 -0.14 505099.0 -13100.0 -0.07 -0.151 -0.9572 2065658 ICCB6_000048 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@H](COC2=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C05 compound treatment 42640.0 -413000.0 -2.46 71405.0 -447000.0 -2.54 -3.5334 -0.9999 2065659 ICCB6_000049 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3Cl)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C06 compound treatment 381952.0 -73400.0 -0.44 429716.0 -88500.0 -0.5 -0.6646 -0.9975 2065660 ICCB6_000050 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C07 compound treatment 365637.0 -89700.0 -0.53 562052.0 43900.0 0.25 -0.2011 -0.3413 2065661 ICCB6_000051 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)CCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C08 compound treatment 477630.0 22300.0 0.13 410528.0 -108000.0 -0.61 -0.3391 -0.5413 2065662 ICCB6_000052 CC(C)[C@@H]1N(C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2)C(=O)OC1(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C09 compound treatment 492056.0 36700.0 0.22 552766.0 34600.0 0.2 0.2935 0.9986 2065663 ICCB6_000053 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C10 compound treatment 124931.0 -330000.0 -1.97 107178.0 -411000.0 -2.34 -3.0432 -0.9963 2065664 ICCB6_000054 COC(=O)[C@H](Cc1ccccc1)NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C11 compound treatment 467600.0 12300.0 0.07 486670.0 -31500.0 -0.18 -0.0752 -0.3883 2065665 ICCB6_000055 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C12 compound treatment 86921.0 -368000.0 -2.19 86745.0 -431000.0 -2.45 -3.2853 -0.9984 2065666 ICCB6_000056 CCc1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C13 compound treatment 74147.0 -381000.0 -2.27 63328.0 -455000.0 -2.59 -3.4332 -0.9979 1065064 ICCB6_000057 [O-][N+](=O)c1ccc(CBr)c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C14 compound treatment 102518.0 -353000.0 -2.1 221439.0 -297000.0 -1.69 -2.6781 -0.9941 2065667 ICCB6_000058 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(Oc3ccccc3)cc2)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C15 compound treatment 288328.0 -167000.0 -0.99 421919.0 -96300.0 -0.55 -1.09 -0.9605 1952482 ICCB6_000059 Fc1ccc(cc1Br)[C@H]2C3=CC[C@H]4[C@@H]([C@@H]3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C16 compound treatment 91714.0 -364000.0 -2.16 99565.0 -419000.0 -2.38 -3.2136 -0.9989 2065668 ICCB6_000060 COc1cccc(C)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C17 compound treatment 438721.0 -16600.0 -0.1 533583.0 15400.0 0.09 -0.0081 -0.061 1952809 ICCB6_000061 CC(=O)Oc1ccccc1C#Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C18 compound treatment 164135.0 -291000.0 -1.73 305469.0 -213000.0 -1.21 -2.0809 -0.9846 2065669 ICCB6_000062 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(C#N)cc2)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C19 compound treatment 345215.0 -110000.0 -0.66 354717.0 -163000.0 -0.93 -1.1208 -0.9854 1952773 ICCB6_000063 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C20 compound treatment 320125.0 -135000.0 -0.8 477281.0 -40900.0 -0.23 -0.7335 -0.8757 2065670 ICCB6_000064 CCOC(=O)CNC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C21 compound treatment 55370.0 -400000.0 -2.38 49527.0 -469000.0 -2.67 -3.5678 -0.9984 1952585 ICCB6_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C22 compound treatment 75919.0 -379000.0 -2.26 128020.0 -390000.0 -2.22 -3.1657 -1.0 2065671 ICCB6_000066 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2F)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C23 mock treatment 465580.0 10200.0 0.06 456884.0 -61300.0 -0.35 -0.2034 -0.5748 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 C24 mock treatment 403261.0 -52100.0 -0.31 440388.0 -77800.0 -0.44 -0.532 -0.9848 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D01 compound treatment 448266.0 -7070.0 -0.04 526965.0 8770.0 0.05 0.0055 0.0844 2065672 ICCB6_000067 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D02 compound treatment 362712.0 -92600.0 -0.55 291949.0 -226000.0 -1.29 -1.2996 -0.9284 2065673 ICCB6_000068 CC(C)[Si](OC[C@@H]1CC=C(C)B(O)O1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D03 compound treatment 82830.0 -373000.0 -2.22 91791.0 -426000.0 -2.42 -3.2823 -0.999 2065674 ICCB6_000069 CCOC(=O)C1[C@H](CCc2ccccc2)O[C@H](CCc3ccccc3)CC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D04 compound treatment 332036.0 -123000.0 -0.73 416138.0 -102000.0 -0.58 -0.9293 -0.9933 2065675 ICCB6_000070 CC(C)[Si](OC[C@H]1OB(O)CC=C1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D05 compound treatment 201179.0 -254000.0 -1.51 430851.0 -87300.0 -0.5 -1.4208 -0.8924 2065676 ICCB6_000071 C[Si](C)(C(N[Si](=O)(=O)c1ccccc1)c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D06 compound treatment 45681.0 -410000.0 -2.44 80690.0 -438000.0 -2.49 -3.4832 -0.9999 2065677 ICCB6_000072 CC(C)[Si](OCC(O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D07 compound treatment 427142.0 -28200.0 -0.17 572008.0 53800.0 0.31 0.0977 0.28 2065678 ICCB6_000073 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D08 compound treatment 328979.0 -126000.0 -0.75 505430.0 -12800.0 -0.07 -0.5831 -0.7718 2065679 ICCB6_000074 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D09 compound treatment 447743.0 -7590.0 -0.05 512498.0 -5700.0 -0.03 -0.0549 -0.9867 2065680 ICCB6_000075 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)CCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D10 compound treatment 408951.0 -46400.0 -0.28 224279.0 -294000.0 -1.67 -1.3771 -0.8129 2065681 ICCB6_000076 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D11 compound treatment 378898.0 -76400.0 -0.45 290155.0 -228000.0 -1.3 -1.2387 -0.9013 2065682 ICCB6_000077 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D12 compound treatment 409022.0 -46300.0 -0.28 396698.0 -121000.0 -0.69 -0.6835 -0.9188 2065683 ICCB6_000078 CC(C)[Si](OCC(O)/C(=C\CO)/C)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D13 compound treatment 397581.0 -57800.0 -0.34 485499.0 -32700.0 -0.19 -0.3745 -0.9584 1952278 ICCB6_000079 COC(=O)c1nc(oc1C)C(NC(=O)CCc2cn(CC=C)c3ccccc23)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D14 compound treatment 446205.0 -9130.0 -0.05 510788.0 -7410.0 -0.04 -0.0682 -0.9921 2065684 ICCB6_000080 CC(C)[Si](OCC(O)/C=C\CO)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D15 compound treatment 64774.0 -391000.0 -2.32 59707.0 -458000.0 -2.61 -3.4873 -0.9984 2065685 ICCB6_000081 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D16 compound treatment 382565.0 -72800.0 -0.43 289237.0 -229000.0 -1.3 -1.2269 -0.8941 2065686 ICCB6_000082 CC(C)[Si](OC[C@@H](O)[C@@]1(C)OC(C)(C)OC1CO)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D17 compound treatment 296556.0 -159000.0 -0.94 379670.0 -139000.0 -0.79 -1.2252 -0.9959 1952811 ICCB6_000083 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D18 compound treatment 383927.0 -71400.0 -0.42 514994.0 -3200.0 -0.02 -0.3134 -0.7367 2065687 ICCB6_000084 CC(C)[Si](OC[C@@H](O)[C@H]1OC(C)(C)OC1CO)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D19 compound treatment 354145.0 -101000.0 -0.6 418851.0 -99300.0 -0.56 -0.8253 -0.9995 1952780 ICCB6_000085 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D20 compound treatment 446433.0 -8900.0 -0.05 564420.0 46200.0 0.26 0.1484 0.5534 2065688 ICCB6_000086 CC1(C)OC(CO)[C@H](O1)[C@H](O)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D21 compound treatment 475312.0 20000.0 0.12 591197.0 73000.0 0.42 0.3776 0.8744 1952670 ICCB6_000087 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D22 compound treatment 374679.0 -80700.0 -0.48 454704.0 -63500.0 -0.36 -0.5947 -0.9901 2065689 ICCB6_000088 C/C(=C/CO)/[C@H](O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D23 mock treatment 446894.0 -8440.0 -0.05 428092.0 -90100.0 -0.51 -0.3979 -0.7727 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 D24 mock treatment 494339.0 39000.0 0.23 472109.0 -46100.0 -0.26 -0.0212 -0.0605 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E01 compound treatment 265656.0 -190000.0 -1.13 584640.0 66400.0 0.38 -0.5311 -0.4461 2065690 ICCB6_000089 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)c(Cl)c4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E02 compound treatment 99937.0 -355000.0 -2.12 110031.0 -408000.0 -2.32 -3.1369 -0.9989 2065691 ICCB6_000090 COc1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E03 compound treatment 37718.0 -418000.0 -2.49 73479.0 -445000.0 -2.53 -3.5457 -1.0 2065692 ICCB6_000091 CCOC(=O)C1[C@@H](O[C@@H](CC1=O)c2ccccc2)C3CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E04 compound treatment 321492.0 -134000.0 -0.8 507355.0 -10800.0 -0.06 -0.6069 -0.7596 2065693 ICCB6_000092 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](O)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E05 compound treatment 50720.0 -405000.0 -2.41 47382.0 -471000.0 -2.68 -3.596 -0.9986 2065694 ICCB6_000093 COc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)[Si](C)(C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E06 compound treatment 449254.0 -6080.0 -0.04 580539.0 62300.0 0.35 0.2251 0.6316 2065695 ICCB6_000094 CC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E07 compound treatment 337084.0 -118000.0 -0.7 379491.0 -139000.0 -0.79 -1.0554 -0.9984 2065696 ICCB6_000095 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E08 compound treatment 195602.0 -260000.0 -1.55 248417.0 -270000.0 -1.53 -2.1779 -1.0 2065697 ICCB6_000096 CCOC(=O)c1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E09 compound treatment 263686.0 -192000.0 -1.14 545071.0 26900.0 0.15 -0.6985 -0.6069 2065698 ICCB6_000097 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E10 compound treatment 101935.0 -353000.0 -2.1 102468.0 -416000.0 -2.36 -3.1589 -0.9983 2065699 ICCB6_000098 CCCCOC(=O)c1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E11 compound treatment 424669.0 -30700.0 -0.18 624983.0 107000.0 0.61 0.3003 0.4737 1952474 ICCB6_000099 OCCCCCNC(CCO)Cc1ccc2ccccc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E12 compound treatment 241314.0 -214000.0 -1.27 242990.0 -275000.0 -1.57 -2.0073 -0.9948 2065700 ICCB6_000100 COC(=O)[C@@H](NC(=O)OC/C=C/c1ccc(CCCCCCO)o1)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E13 compound treatment 177425.0 -278000.0 -1.65 453753.0 -64400.0 -0.37 -1.4287 -0.8433 1952280 ICCB6_000101 COC(=O)c1nc2oc1CC/C=C/Cn3cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C)c4ccccc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E14 compound treatment 46369.0 -409000.0 -2.43 79908.0 -438000.0 -2.49 -3.4835 -0.9999 2065701 ICCB6_000102 COc1cccc(Cl)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E15 compound treatment 114360.0 -341000.0 -2.03 66156.0 -452000.0 -2.57 -3.2526 -0.9931 1952487 ICCB6_000103 Fc1ccc(cc1Br)[C@H]2C3=CCn4n(C3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)c(=O)n(c6ccccc6)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E16 compound treatment 367450.0 -87900.0 -0.52 544263.0 26100.0 0.15 -0.265 -0.4875 2065702 ICCB6_000104 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E17 compound treatment 251974.0 -203000.0 -1.21 388267.0 -130000.0 -0.74 -1.3783 -0.972 1952813 ICCB6_000105 OCCCC#Cc1cc(O)cc(Cl)c1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E18 compound treatment 479925.0 24600.0 0.15 481582.0 -36600.0 -0.21 -0.0438 -0.1719 2065703 ICCB6_000106 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](OC(=O)C)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E19 compound treatment 462746.0 7410.0 0.04 362504.0 -156000.0 -0.89 -0.5949 -0.6711 3107406 ICCB6_000107 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E20 compound treatment 494820.0 39500.0 0.23 513005.0 -5190.0 -0.03 0.1453 0.6135 2065704 ICCB6_000108 C[C@@H]([C@H](OC(=O)C)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E21 compound treatment 220065.0 -235000.0 -1.4 506595.0 -11600.0 -0.07 -1.0367 -0.7396 ICCB6_000109 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E22 compound treatment 448141.0 -7200.0 -0.04 498265.0 -19900.0 -0.11 -0.1104 -0.9114 2065705 ICCB6_000110 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2cccc(C)c2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E23 mock treatment 489092.0 33800.0 0.2 532384.0 14200.0 0.08 0.1991 0.9197 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 E24 mock treatment 532459.0 77100.0 0.46 595155.0 77000.0 0.44 0.634 0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F01 compound treatment 395421.0 -59900.0 -0.36 578108.0 59900.0 0.34 -0.0112 -0.0228 2065706 ICCB6_000111 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(OC)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F02 compound treatment 105943.0 -349000.0 -2.08 188874.0 -329000.0 -1.87 -2.7946 -0.9986 2065707 ICCB6_000112 CC(C)[Si](OC[C@@H](O)C(C=C)C(O)c1ccccc1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F03 compound treatment 158108.0 -297000.0 -1.77 316060.0 -202000.0 -1.15 -2.0636 -0.9782 1009686 ICCB6_000113 O=C(CC(C(=O)c1ccccc1)c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F04 compound treatment 463439.0 8100.0 0.05 562972.0 44800.0 0.25 0.2141 0.8263 2065708 ICCB6_000114 OC/C=C\C(O)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F05 compound treatment 99401.0 -356000.0 -2.12 367949.0 -150000.0 -0.85 -2.102 -0.9203 2065709 ICCB6_000115 CCCCCCCCNC(=O)CC[C@H]1O[C@H](O[C@H]2O[C@H](CCC(=O)NCCCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F06 compound treatment 381221.0 -74100.0 -0.44 575285.0 57100.0 0.32 -0.0823 -0.1503 2065710 ICCB6_000116 CC1=C([C@H](O)C(C)(C)C)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F07 compound treatment 507900.0 52600.0 0.31 503697.0 -14500.0 -0.08 0.1629 0.5035 2065711 ICCB6_000117 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F08 compound treatment 453153.0 -2180.0 -0.01 329365.0 -189000.0 -1.07 -0.7685 -0.7156 2065712 ICCB6_000118 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F09 compound treatment 200941.0 -254000.0 -1.51 360262.0 -158000.0 -0.9 -1.7056 -0.9689 2065713 ICCB6_000119 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F10 compound treatment 363493.0 -91800.0 -0.55 290517.0 -228000.0 -1.29 -1.302 -0.9264 2065714 ICCB6_000120 C[C@@H](O)C1=CC[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F11 compound treatment 282038.0 -173000.0 -1.03 107868.0 -410000.0 -2.33 -2.3793 -0.9326 1952476 ICCB6_000121 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2c(Br)sc3ccc(Cl)cc23)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F12 compound treatment 488750.0 33400.0 0.2 465347.0 -52800.0 -0.3 -0.0719 -0.1995 2065715 ICCB6_000122 OC[C@@H]1[C@H]2[C@@H](CC=C1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F13 compound treatment 205916.0 -249000.0 -1.48 275002.0 -243000.0 -1.38 -2.0276 -0.9994 1952282 ICCB6_000123 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F14 compound treatment 444272.0 -11100.0 -0.07 179233.0 -339000.0 -1.93 -1.4096 -0.7308 2065716 ICCB6_000124 CC1=C(CO)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F15 compound treatment 64812.0 -391000.0 -2.32 55064.0 -463000.0 -2.63 -3.5058 -0.9981 1952488 ICCB6_000125 Fc1ccc(cc1Br)[C@H]2C3=CCC4=C(C3CC5=C2C(=O)C(=CC5=O)I)C(=O)C(=CC4=O)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F16 compound treatment 203110.0 -252000.0 -1.5 483610.0 -34600.0 -0.2 -1.2005 -0.793 2065717 ICCB6_000126 C/C(=C/CO)/C(O)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F17 compound treatment 347186.0 -108000.0 -0.64 186026.0 -332000.0 -1.89 -1.7908 -0.8974 1952814 ICCB6_000127 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F18 compound treatment 450663.0 -4670.0 -0.03 358213.0 -160000.0 -0.91 -0.663 -0.7284 2065718 ICCB6_000128 CC(C)[Si](OCC1OB(O)CC=C1C)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F19 compound treatment 139637.0 -316000.0 -1.88 375541.0 -143000.0 -0.81 -1.9022 -0.9295 1952785 ICCB6_000129 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F20 compound treatment 112292.0 -343000.0 -2.04 101995.0 -416000.0 -2.37 -3.1172 -0.9973 2065719 ICCB6_000130 OB1CC=C(C(O1)c2ccccc2)C(=C)COCc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F21 compound treatment 424983.0 -30400.0 -0.18 438255.0 -79900.0 -0.45 -0.4492 -0.9183 3107360 ICCB6_000131 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F22 compound treatment 85569.0 -370000.0 -2.2 55841.0 -462000.0 -2.63 -3.4153 -0.9961 2065720 ICCB6_000132 OC/C=C(\C(O)c1ccccc1)/C(=C)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F23 mock treatment 475996.0 20700.0 0.12 443125.0 -75100.0 -0.43 -0.2149 -0.4838 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 F24 mock treatment 538835.0 83500.0 0.5 498379.0 -19800.0 -0.11 0.2717 0.5332 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G01 compound treatment 477271.0 21900.0 0.13 583479.0 65300.0 0.37 0.3548 0.9016 2065721 ICCB6_000133 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4cccs4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G02 compound treatment 517911.0 62600.0 0.37 492023.0 -26200.0 -0.15 0.1581 0.3942 3057351 ICCB6_000134 CC(C)C[C@H](CI)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G03 compound treatment 163236.0 -292000.0 -1.74 291146.0 -227000.0 -1.29 -2.1422 -0.9893 2065722 ICCB6_000135 Clc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)C(=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G04 compound treatment 479146.0 23800.0 0.14 520364.0 2170.0 0.01 0.1089 0.7657 3057353 ICCB6_000136 CC(C)(C)OC[C@@H](O)[C@H]1O[C@H](NO)C2OC(C)(C)OC12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G05 compound treatment 528953.0 73600.0 0.44 568012.0 49800.0 0.28 0.5101 0.9777 2065723 ICCB6_000137 CCCCCCCNCC(=O)NC[C@H]1O[C@H](O[C@H]2O[C@H](CNC(=O)CCNCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G06 compound treatment 506987.0 51600.0 0.31 499197.0 -19000.0 -0.11 0.141 0.4326 2065724 ICCB6_000138 CC(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G07 compound treatment 546784.0 91400.0 0.54 526908.0 8710.0 0.05 0.4199 0.7683 2065725 ICCB6_000139 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G08 compound treatment 496145.0 40800.0 0.24 589208.0 71000.0 0.4 0.4573 0.9704 2065726 ICCB6_000140 CC(C)(C)[Si](C)(C)OCC1=CC(C#C)N(C=C1)C(=O)c2ccccc2Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G09 compound treatment 478536.0 23200.0 0.14 590886.0 72700.0 0.41 0.3899 0.8947 2065727 ICCB6_000141 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G10 compound treatment 474612.0 19300.0 0.11 489761.0 -28400.0 -0.16 -0.0332 -0.1676 3057357 ICCB6_000142 OC(=O)c1[se]c2ccccc2c1Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G11 compound treatment 436481.0 -18900.0 -0.11 433711.0 -84500.0 -0.48 -0.4191 -0.8494 1952478 ICCB6_000143 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2ccc3ccccc3c2Br)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G12 compound treatment 48054.0 -407000.0 -2.42 84351.0 -434000.0 -2.47 -3.4585 -1.0 3057359 ICCB6_000144 CC(C)(C)[Si](C)(C)OCC1=CC(C=C)N(C=C1)C(=O)c2[se]c3ccccc3c2Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G13 compound treatment 260935.0 -194000.0 -1.16 342738.0 -175000.0 -1.0 -1.5236 -0.9973 1952284 ICCB6_000145 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]2C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G14 compound treatment 172055.0 -283000.0 -1.69 272649.0 -246000.0 -1.4 -2.1795 -0.9956 2065728 ICCB6_000146 CCCCCC1C=C(CO[Si](C)(C)C(C)(C)C)C=CN1C(=O)c2ccccc2Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G15 compound treatment 240159.0 -215000.0 -1.28 270440.0 -248000.0 -1.41 -1.9018 -0.9989 2065729 ICCB6_000147 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G16 compound treatment 197866.0 -257000.0 -1.53 233788.0 -284000.0 -1.62 -2.2272 -0.9996 2065730 ICCB6_000148 CC(C)(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G17 compound treatment 374692.0 -80600.0 -0.48 575233.0 57000.0 0.32 -0.11 -0.1899 1952760 ICCB6_000149 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G18 compound treatment 166226.0 -289000.0 -1.72 415478.0 -103000.0 -0.58 -1.6297 -0.8969 2065731 ICCB6_000150 CC(=O)N[C@@H](CI)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G19 compound treatment 155502.0 -300000.0 -1.78 396558.0 -122000.0 -0.69 -1.7509 -0.9149 1952788 ICCB6_000151 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G20 compound treatment 248321.0 -207000.0 -1.23 243658.0 -275000.0 -1.56 -1.9751 -0.9931 2065732 ICCB6_000152 COc1cc2CCN(Cc3ccccc3Br)C(C=C)c2cc1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G21 compound treatment 428850.0 -26500.0 -0.16 474421.0 -43800.0 -0.25 -0.2875 -0.9757 1952728 ICCB6_000153 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G22 compound treatment 464498.0 9160.0 0.05 464625.0 -53600.0 -0.3 -0.1769 -0.5715 2065733 ICCB6_000154 CN1C(=O)C2C(C1=O)C3(C4C(C5C=C(CCCO[Si](C)(C)C(C)(C)C)CC2N53)C(=O)N(C)C4=O)C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G23 mock treatment 292554.0 -163000.0 -0.97 221038.0 -297000.0 -1.69 -1.88 -0.9651 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 G24 mock treatment 441820.0 -13500.0 -0.08 495013.0 -23200.0 -0.13 -0.1501 -0.9719 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H01 compound treatment 319335.0 -136000.0 -0.81 553459.0 35300.0 0.2 -0.4305 -0.5163 2065734 ICCB6_000155 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4Cl)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H02 compound treatment 228169.0 -227000.0 -1.35 547472.0 29300.0 0.17 -0.8383 -0.6154 2065735 ICCB6_000156 CC(=C)C1=CCB(O)OC1c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H03 compound treatment 297868.0 -157000.0 -0.94 606576.0 88400.0 0.5 -0.3073 -0.289 2065736 ICCB6_000157 CC(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H04 compound treatment 418506.0 -36800.0 -0.22 504382.0 -13800.0 -0.08 -0.2105 -0.9042 2065737 ICCB6_000158 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H05 compound treatment 334836.0 -121000.0 -0.72 534575.0 16400.0 0.09 -0.4412 -0.6101 2065738 ICCB6_000159 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H06 compound treatment 314876.0 -140000.0 -0.84 471488.0 -46700.0 -0.27 -0.7789 -0.888 2065739 ICCB6_000160 CC(=C)/C(=C/CO)/C(O)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H07 compound treatment 441343.0 -14000.0 -0.08 292492.0 -226000.0 -1.28 -0.9665 -0.7514 2065740 ICCB6_000161 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H08 compound treatment 112700.0 -343000.0 -2.04 85788.0 -432000.0 -2.46 -3.1807 -0.9957 2065741 ICCB6_000162 CC1=NC(C)(C)[C@@H]2CCC(=C)C1C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H09 compound treatment 301835.0 -154000.0 -0.91 358865.0 -159000.0 -0.91 -1.2867 -1.0 2065742 ICCB6_000163 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H10 compound treatment 228993.0 -226000.0 -1.35 238707.0 -279000.0 -1.59 -2.0764 -0.9966 2065743 ICCB6_000164 C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H11 compound treatment 143482.0 -312000.0 -1.86 277486.0 -241000.0 -1.37 -2.2803 -0.9888 1952534 ICCB6_000165 C[C@H](N)C(Oc1ccccc1Br)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H12 compound treatment 588155.0 133000.0 0.79 318851.0 -199000.0 -1.13 -0.2427 -0.1756 2065744 ICCB6_000166 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H13 compound treatment 437142.0 -18200.0 -0.11 507746.0 -10400.0 -0.06 -0.1186 -0.9601 1952286 ICCB6_000167 COC(=O)c1nc(oc1CCC=C)C(NC(=O)[C@H](Cc2cn(CC=C)cn2)NC(=O)OCc3ccccc3)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H14 compound treatment 415836.0 -39500.0 -0.24 504423.0 -13800.0 -0.08 -0.2216 -0.8944 2065745 ICCB6_000168 CC(C)C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H15 compound treatment 66298.0 -389000.0 -2.32 61386.0 -457000.0 -2.6 -3.4741 -0.9984 1952677 ICCB6_000169 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H16 compound treatment 475003.0 19700.0 0.12 470784.0 -47400.0 -0.27 -0.1079 -0.3671 2065746 ICCB6_000170 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H17 compound treatment 222097.0 -233000.0 -1.39 239663.0 -279000.0 -1.58 -2.1016 -0.9978 1952821 ICCB6_000171 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H18 compound treatment 202324.0 -253000.0 -1.51 150890.0 -367000.0 -2.09 -2.5417 -0.9871 2065747 ICCB6_000172 COc1cc(C[C@H]2NC(C)(C)C3CCC(=C)[C@H]2C3)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H19 compound treatment 193085.0 -262000.0 -1.56 493004.0 -25200.0 -0.14 -1.2049 -0.7688 1952600 ICCB6_000173 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H20 compound treatment 428494.0 -26800.0 -0.16 363811.0 -154000.0 -0.88 -0.7338 -0.8223 2065748 ICCB6_000174 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2C)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H21 compound treatment 453185.0 -2150.0 -0.01 410201.0 -108000.0 -0.61 -0.4433 -0.7217 1952730 ICCB6_000175 O=c1cc(Cc2ccccc2)c3ccccc3o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H22 compound treatment 69212.0 -386000.0 -2.3 47378.0 -471000.0 -2.68 -3.5182 -0.9971 2065749 ICCB6_000176 CC1(C)N=C(/C=C/2\C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H23 mock treatment 173408.0 -282000.0 -1.68 439971.0 -78200.0 -0.44 -1.501 -0.8647 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 H24 mock treatment 492766.0 37400.0 0.22 482895.0 -35300.0 -0.2 0.0156 0.0519 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I01 compound treatment 452106.0 -3230.0 -0.02 557259.0 39100.0 0.22 0.1435 0.6435 2065750 ICCB6_000177 COC(=O)[C@@H]1[C@H](N([C@H](c2ccccc2)[C@@]13C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6)C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I02 compound treatment 86964.0 -368000.0 -2.19 83828.0 -434000.0 -2.47 -3.2969 -0.9982 2065751 ICCB6_000178 CC(C)(C)[Si](C)(C)OCCCC1=CC2C3C(C(=O)N(Cc4ccccc4)C3=O)C5(C6C(C(C1)N25)C(=O)N(Cc7ccccc7)C6=O)C(=O)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I03 compound treatment 462367.0 7030.0 0.04 387319.0 -131000.0 -0.74 -0.4967 -0.6663 2065752 ICCB6_000179 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Cl)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I04 compound treatment 287241.0 -168000.0 -1.0 382740.0 -135000.0 -0.77 -1.2521 -0.9917 2065753 ICCB6_000180 COc1cc(CN[C@@H](C)[C@H](Oc2ccccc2Br)c3ccccc3)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I05 compound treatment 560450.0 105000.0 0.63 588667.0 70500.0 0.4 0.7257 0.9768 2065754 ICCB6_000181 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I06 compound treatment 500092.0 44800.0 0.27 513761.0 -4430.0 -0.03 0.1705 0.6373 2065755 ICCB6_000182 COc1cc(CN[C@H]([C@H](O)c2ccccc2)c3ccccc3)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I07 compound treatment 476811.0 21500.0 0.13 587402.0 69200.0 0.39 0.3687 0.8909 2065756 ICCB6_000183 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I08 compound treatment 328484.0 -127000.0 -0.75 313120.0 -205000.0 -1.17 -1.3585 -0.9778 2065757 ICCB6_000184 COc1cc(CN(Cc2ccccc2Br)[C@H]([C@H](O)c3ccccc3)c4ccccc4)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I09 compound treatment 539525.0 84200.0 0.5 589111.0 70900.0 0.4 0.6394 0.9942 2065758 ICCB6_000185 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I10 compound treatment 412400.0 -42900.0 -0.26 491228.0 -27000.0 -0.15 -0.2891 -0.9702 2065759 ICCB6_000186 COc1cc(CN(Cc2ccccc2Br)[C@H](C)C(Oc3ccccc3Br)c4ccccc4)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I11 compound treatment 523075.0 67700.0 0.4 561261.0 43100.0 0.24 0.4582 0.9715 1952544 ICCB6_000187 O=C1Nc2ccccc2[C@@]31[C@@H](C#N)C4N([C@H]3c5ccccc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I12 compound treatment 497097.0 41800.0 0.25 538330.0 20100.0 0.11 0.2567 0.9381 2065760 ICCB6_000188 COc1cc(CN(Cc2ccccc2Br)[C@H](C(Oc3ccccc3Br)c4ccccc4)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I13 compound treatment 208816.0 -247000.0 -1.47 185069.0 -333000.0 -1.89 -2.377 -0.992 1952288 ICCB6_000189 COC(=O)c1nc2oc1CC/C=C/Cn3cnc(C[C@H](NC(=O)OCc4ccccc4)C(=O)NC2C(C)C)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I14 compound treatment 497440.0 42100.0 0.25 538321.0 20100.0 0.11 0.2581 0.937 2065761 ICCB6_000190 C[C@@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I15 compound treatment 224095.0 -231000.0 -1.38 549191.0 31000.0 0.18 -0.8485 -0.6115 1952679 ICCB6_000191 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I16 compound treatment 433514.0 -21800.0 -0.13 475111.0 -43100.0 -0.25 -0.2651 -0.9559 2065762 ICCB6_000192 C[C@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I17 compound treatment 82841.0 -372000.0 -2.22 80449.0 -438000.0 -2.49 -3.3278 -0.9983 1952823 ICCB6_000193 C#Cc1ccccc1Oc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I18 compound treatment 453490.0 -1850.0 -0.01 345814.0 -172000.0 -0.98 -0.7009 -0.715 2065763 ICCB6_000194 C[C@H](C(Oc1ccc(cc1)[N+](=O)[O-])c2ccccc2)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I19 compound treatment 62294.0 -393000.0 -2.34 57716.0 -460000.0 -2.62 -3.5057 -0.9984 1952601 ICCB6_000195 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I20 compound treatment 455750.0 413.0 0.0 377688.0 -141000.0 -0.8 -0.5633 -0.7049 2065764 ICCB6_000196 C[C@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I21 compound treatment 22309.0 -433000.0 -2.58 52626.0 -466000.0 -2.65 -3.6944 -0.9999 1952746 ICCB6_000197 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I22 compound treatment 413128.0 -42200.0 -0.25 478330.0 -39900.0 -0.23 -0.3379 -0.9987 2065765 ICCB6_000198 C[C@@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I23 mock treatment 423258.0 -32100.0 -0.19 529358.0 11200.0 0.06 -0.0901 -0.4479 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 I24 mock treatment 164937.0 -290000.0 -1.73 458190.0 -60000.0 -0.34 -1.4634 -0.8307 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J01 compound treatment 74107.0 -381000.0 -2.27 82026.0 -436000.0 -2.48 -3.3582 -0.999 2065766 ICCB6_000199 COC(=O)C1=CN([C@H](c2ccccc2)[C@]31C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J02 compound treatment 208366.0 -247000.0 -1.47 243151.0 -275000.0 -1.56 -2.1453 -0.9995 2065767 ICCB6_000200 CC1(C)N[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J03 compound treatment 448877.0 -6460.0 -0.04 571018.0 52800.0 0.3 0.1852 0.6116 2065768 ICCB6_000201 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Br)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J04 compound treatment 490942.0 35600.0 0.21 513950.0 -4250.0 -0.02 0.1328 0.6225 2065769 ICCB6_000202 CN1[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J05 compound treatment 217460.0 -238000.0 -1.42 569336.0 51100.0 0.29 -0.7954 -0.5504 2065770 ICCB6_000203 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J06 compound treatment 84266.0 -371000.0 -2.21 76600.0 -442000.0 -2.51 -3.3373 -0.9979 2065771 ICCB6_000204 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J07 compound treatment 529622.0 74300.0 0.44 640299.0 122000.0 0.69 0.8036 0.9762 2065772 ICCB6_000205 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J08 compound treatment 131852.0 -323000.0 -1.93 163707.0 -354000.0 -2.02 -2.7868 -0.9997 2065773 ICCB6_000206 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J09 compound treatment 487287.0 31900.0 0.19 197406.0 -321000.0 -1.82 -1.1555 -0.63 2065774 ICCB6_000207 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J10 compound treatment 57735.0 -398000.0 -2.37 74682.0 -444000.0 -2.52 -3.4567 -0.9995 2065775 ICCB6_000208 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J11 compound treatment 385206.0 -70100.0 -0.42 422936.0 -95300.0 -0.54 -0.6782 -0.9917 2065776 ICCB6_000209 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J12 compound treatment 429194.0 -26100.0 -0.16 397657.0 -121000.0 -0.69 -0.5947 -0.8461 2065777 ICCB6_000210 OCCOc1cccc(c1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J13 compound treatment 68542.0 -387000.0 -2.3 65903.0 -452000.0 -2.57 -3.4465 -0.9985 1952295 ICCB6_000211 COC(=O)c1nc(oc1CC(=O)CCl)C(NC(=O)NC(=O)OC(C)(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J14 compound treatment 192726.0 -263000.0 -1.56 134858.0 -383000.0 -2.18 -2.6466 -0.9867 2065778 ICCB6_000212 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J15 compound treatment 167790.0 -288000.0 -1.71 468102.0 -50100.0 -0.28 -1.4115 -0.8136 1952690 ICCB6_000213 COC(=O)CC(C(=O)OC)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J16 compound treatment 466688.0 11400.0 0.07 468494.0 -49700.0 -0.28 -0.1521 -0.5234 2065779 ICCB6_000214 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC(C(=O)OC)C(=O)OC)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J17 compound treatment 77583.0 -378000.0 -2.25 286073.0 -232000.0 -1.32 -2.5231 -0.9678 1952825 ICCB6_000215 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J18 compound treatment 196750.0 -259000.0 -1.54 329606.0 -189000.0 -1.07 -1.8466 -0.9844 2065780 ICCB6_000216 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J19 compound treatment 46021.0 -409000.0 -2.44 48566.0 -470000.0 -2.67 -3.611 -0.9989 1952605 ICCB6_000217 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J20 compound treatment 492396.0 37100.0 0.22 509156.0 -9040.0 -0.05 0.1196 0.5281 2065781 ICCB6_000218 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J21 compound treatment 322011.0 -133000.0 -0.79 442561.0 -75600.0 -0.43 -0.8652 -0.9586 3005760 ICCB6_000219 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J22 compound treatment 526969.0 71600.0 0.43 445792.0 -72400.0 -0.41 0.0103 0.0174 2065782 ICCB6_000220 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCNC(=O)N)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J23 mock treatment 78412.0 -377000.0 -2.24 513379.0 -4820.0 -0.03 -1.6056 -0.7157 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 J24 mock treatment 460165.0 4830.0 0.03 523050.0 4850.0 0.03 0.0398 0.9998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K01 compound treatment 509995.0 54700.0 0.33 556370.0 38200.0 0.22 0.3835 0.9807 2065783 ICCB6_000221 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C)c5ccccc52 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K02 compound treatment 544225.0 88900.0 0.53 657374.0 139000.0 0.79 0.9337 0.9808 2065784 ICCB6_000222 CC(Oc1ccccc1Br)[C@H](N(C)C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K03 compound treatment 495154.0 39800.0 0.24 550191.0 32000.0 0.18 0.2962 0.9915 2065785 ICCB6_000223 COC(=O)C(C(c1ccc(OC)cc1)[Si](C)(C)c2ccccc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K04 compound treatment 534874.0 79500.0 0.47 600624.0 82400.0 0.47 0.6662 1.0 2065786 ICCB6_000224 C[C@H](C(Oc1ccccc1[N+](=O)[O-])c2ccccc2)N(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K05 compound treatment 561277.0 106000.0 0.63 619333.0 101000.0 0.58 0.8525 0.9989 2065787 ICCB6_000225 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K06 compound treatment 93727.0 -362000.0 -2.15 81541.0 -437000.0 -2.48 -3.2776 -0.9975 2065788 ICCB6_000226 COc1cc(/C=C/C=O)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K07 compound treatment 573338.0 118000.0 0.7 524744.0 6550.0 0.04 0.5229 0.7436 2065789 ICCB6_000227 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)CCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K08 compound treatment 85853.0 -369000.0 -2.2 74566.0 -444000.0 -2.52 -3.3388 -0.9977 2065790 ICCB6_000228 COc1cc(/C=C/CN[C@H](C)[C@@H](O)c2ccccc2)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K09 compound treatment 563628.0 108000.0 0.64 602674.0 84500.0 0.48 0.7954 0.9895 2065791 ICCB6_000229 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K10 compound treatment 451819.0 -3520.0 -0.02 552214.0 34000.0 0.19 0.122 0.6269 2065792 ICCB6_000230 CC(C)[Si](OCC1CCC=CC1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K11 compound treatment 522420.0 67100.0 0.4 547819.0 29600.0 0.17 0.4014 0.9264 1034979 ICCB6_000231 c1c(cn2ccccc12)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K12 compound treatment 525021.0 69700.0 0.41 509959.0 -8240.0 -0.05 0.2601 0.6233 2065793 ICCB6_000232 CC1(C)COC(=O)C1OC(=O)C2CC3CCC2C=C3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K13 compound treatment 66912.0 -388000.0 -2.31 67932.0 -450000.0 -2.56 -3.4452 -0.9987 1952379 ICCB6_000233 CC(C)[Si](OCc1ccc(C=O)o1)(C(C)C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K14 compound treatment 501611.0 46300.0 0.28 537521.0 19300.0 0.11 0.2724 0.9188 2065794 ICCB6_000234 OCC1CC2CCC1C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K15 compound treatment 426078.0 -29300.0 -0.17 444023.0 -74200.0 -0.42 -0.4214 -0.9234 1952707 ICCB6_000235 CCCCSc1cc(=O)oc2cc(OC)ccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K16 compound treatment 36328.0 -419000.0 -2.49 65597.0 -453000.0 -2.57 -3.5833 -0.9999 2065795 ICCB6_000236 Ic1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K17 compound treatment 64568.0 -391000.0 -2.33 56121.0 -462000.0 -2.63 -3.5025 -0.9981 1952828 ICCB6_000237 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K18 compound treatment 489997.0 34700.0 0.21 586290.0 68100.0 0.39 0.4197 0.9565 2065796 ICCB6_000238 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3cccnc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K19 compound treatment 73754.0 -382000.0 -2.27 68012.0 -450000.0 -2.56 -3.4161 -0.9982 1952608 ICCB6_000239 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K20 compound treatment 374781.0 -80600.0 -0.48 340817.0 -177000.0 -1.01 -1.0523 -0.9422 2065797 ICCB6_000240 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3ccco3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K21 compound treatment 473689.0 18400.0 0.11 456774.0 -61400.0 -0.35 -0.1698 -0.4639 3005761 ICCB6_000241 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K22 compound treatment 56557.0 -399000.0 -2.37 49384.0 -469000.0 -2.67 -3.5633 -0.9983 2065798 ICCB6_000242 Ic1ccc2NC(=O)/C(=C/C#N)/c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K23 mock treatment 224603.0 -231000.0 -1.37 613951.0 95800.0 0.54 -0.586 -0.3967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 K24 mock treatment 414153.0 -41200.0 -0.25 586886.0 68700.0 0.39 0.1029 0.2231 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L01 compound treatment 106167.0 -349000.0 -2.08 248026.0 -270000.0 -1.54 -2.5558 -0.989 2065799 ICCB6_000243 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccccc52 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L02 compound treatment 446822.0 -8520.0 -0.05 533162.0 15000.0 0.09 0.0243 0.2458 2065800 ICCB6_000244 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#Cc6ccccc6F)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L03 compound treatment 598291.0 143000.0 0.85 603055.0 84900.0 0.48 0.9428 0.9639 2065801 ICCB6_000245 COC(=O)C(C(c1ccco1)[Si](C)(C)c2ccccc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L04 compound treatment 346133.0 -109000.0 -0.65 583729.0 65500.0 0.37 -0.196 -0.2617 2065802 ICCB6_000246 CCCCC[C@H](O)C#Cc1ccc2NC(=O)[C@@]3([C@H](C4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N(C)OC)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L05 compound treatment 341877.0 -113000.0 -0.68 574722.0 56500.0 0.32 -0.2502 -0.3345 2065803 ICCB6_000247 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L06 compound treatment 631499.0 176000.0 1.05 559724.0 41500.0 0.24 0.9083 0.8452 2065804 ICCB6_000248 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)[C@H](C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L07 compound treatment 477212.0 21900.0 0.13 678986.0 161000.0 0.91 0.7386 0.7997 2065805 ICCB6_000249 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L08 compound treatment 159848.0 -295000.0 -1.76 229026.0 -289000.0 -1.64 -2.4063 -0.9994 2065806 ICCB6_000250 OCCOc1ccc(cc1)C2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L09 compound treatment 256325.0 -199000.0 -1.18 522859.0 4660.0 0.03 -0.8187 -0.6911 2065807 ICCB6_000251 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L10 compound treatment 521966.0 66600.0 0.4 525742.0 7550.0 0.04 0.3107 0.7791 2065808 ICCB6_000252 CON(C)C(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(I)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L11 compound treatment 227965.0 -227000.0 -1.35 214211.0 -304000.0 -1.73 -2.1792 -0.9927 2065809 ICCB6_000253 COC(=O)Cc1cn[nH]c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L12 compound treatment 164180.0 -291000.0 -1.73 414159.0 -104000.0 -0.59 -1.6436 -0.8977 2065810 ICCB6_000254 CCOC(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(Br)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L13 compound treatment 74532.0 -381000.0 -2.27 68401.0 -450000.0 -2.56 -3.4112 -0.9982 1952411 ICCB6_000255 CC(C)[Si](OCc1ccc(o1)[C@@H](O)[C@H](C)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3)(C(C)C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L14 compound treatment 316144.0 -139000.0 -0.83 336459.0 -182000.0 -1.03 -1.3166 -0.994 2065811 ICCB6_000256 OCCOc1ccc(cc1)C2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L15 compound treatment 388704.0 -66600.0 -0.4 368148.0 -150000.0 -0.85 -0.8838 -0.9393 1952793 ICCB6_000257 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L16 compound treatment 654111.0 199000.0 1.18 480095.0 -38100.0 -0.22 0.6833 0.5681 2065812 ICCB6_000258 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L17 compound treatment 161489.0 -294000.0 -1.75 524759.0 6560.0 0.04 -1.2102 -0.6919 1952829 ICCB6_000259 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L18 compound treatment 78794.0 -377000.0 -2.24 259912.0 -258000.0 -1.47 -2.6232 -0.979 2065813 ICCB6_000260 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L19 compound treatment 334144.0 -121000.0 -0.72 512502.0 -5690.0 -0.03 -0.5329 -0.7381 1952582 ICCB6_000261 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L20 compound treatment 341619.0 -114000.0 -0.68 110721.0 -407000.0 -2.32 -2.1171 -0.877 2065814 ICCB6_000262 CON(C)C(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(Br)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L21 compound treatment 472269.0 16900.0 0.1 567274.0 49100.0 0.28 0.2686 0.9052 1952748 ICCB6_000263 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L22 compound treatment 310565.0 -145000.0 -0.86 362799.0 -155000.0 -0.88 -1.2341 -0.9999 2065815 ICCB6_000264 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L23 mock treatment 429164.0 -26200.0 -0.16 486781.0 -31400.0 -0.18 -0.2365 -0.9977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 L24 mock treatment 444141.0 -11200.0 -0.07 479262.0 -38900.0 -0.22 -0.2037 -0.8809 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M01 compound treatment 79796.0 -376000.0 -2.24 83227.0 -435000.0 -2.47 -3.3295 -0.9987 2065816 ICCB6_000265 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccc(Cl)cc52 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M02 compound treatment 403958.0 -51400.0 -0.31 395829.0 -122000.0 -0.7 -0.7083 -0.9318 2065817 ICCB6_000266 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M03 compound treatment 573623.0 118000.0 0.7 580304.0 62100.0 0.35 0.7475 0.9491 2065818 ICCB6_000267 COc1ccc(cc1)C(CC(=O)c2ccccc2)[Si](C)(C)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M04 compound treatment 387251.0 -68100.0 -0.41 472481.0 -45700.0 -0.26 -0.4704 -0.977 2065819 ICCB6_000268 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M05 compound treatment 610666.0 155000.0 0.92 571970.0 53800.0 0.31 0.8699 0.8934 2065820 ICCB6_000269 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M06 compound treatment 101053.0 -354000.0 -2.11 82770.0 -435000.0 -2.48 -3.2418 -0.9968 2065821 ICCB6_000270 COC(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M07 compound treatment 558115.0 103000.0 0.61 513516.0 -4680.0 -0.03 0.4137 0.6757 2065822 ICCB6_000271 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M08 compound treatment 533189.0 77900.0 0.46 560936.0 42700.0 0.24 0.4995 0.9547 2065823 ICCB6_000272 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCC4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M09 compound treatment 582783.0 127000.0 0.76 555199.0 37000.0 0.21 0.6851 0.8704 2065824 ICCB6_000273 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M10 compound treatment 383218.0 -72100.0 -0.43 461504.0 -56700.0 -0.32 -0.5315 -0.9901 2065825 ICCB6_000274 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4ccccc4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M11 compound treatment 574743.0 119000.0 0.71 542610.0 24400.0 0.14 0.6007 0.8296 2065826 ICCB6_000275 CC(C(=O)O)c1ccccc1C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M12 compound treatment 511672.0 56300.0 0.34 531442.0 13200.0 0.08 0.2903 0.8449 2065827 ICCB6_000276 OCCNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(I)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M13 compound treatment 162061.0 -293000.0 -1.75 186570.0 -332000.0 -1.89 -2.5677 -0.9993 1952416 ICCB6_000277 Clc1c(Cl)c(Cl)c(OCc2ccccc2)c(Cl)c1Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M14 compound treatment 378162.0 -77200.0 -0.46 376176.0 -142000.0 -0.81 -0.8959 -0.9642 2065828 ICCB6_000278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M15 compound treatment 163454.0 -292000.0 -1.74 398277.0 -120000.0 -0.68 -1.7105 -0.9166 1952795 ICCB6_000279 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M16 compound treatment 575950.0 121000.0 0.72 648746.0 131000.0 0.74 1.0325 0.9999 2065829 ICCB6_000280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)C(C(OC3=O)c5ccccc5)c6ccccc6)C(=O)N(C)OC)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M17 compound treatment 447279.0 -8060.0 -0.05 537074.0 18900.0 0.11 0.042 0.3572 1952832 ICCB6_000281 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M18 compound treatment 578732.0 123000.0 0.73 659965.0 142000.0 0.81 1.0894 0.9989 3176523 ICCB6_000282 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCC(C)C)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M19 compound treatment 551597.0 96300.0 0.57 305965.0 -212000.0 -1.21 -0.4483 -0.3356 1952627 ICCB6_000283 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M20 compound treatment 485702.0 30400.0 0.18 479160.0 -39000.0 -0.22 -0.0292 -0.102 3056713 ICCB6_000284 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@@H](C(C)C)C(=O)OC)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M21 compound treatment 55098.0 -400000.0 -2.38 51995.0 -466000.0 -2.65 -3.559 -0.9986 1107217 ICCB6_000285 Cc1cccnc1I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M22 compound treatment 130193.0 -325000.0 -1.94 218346.0 -300000.0 -1.71 -2.574 -0.998 3176524 ICCB6_000286 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@H](C)c5ccccc5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M23 mock treatment 401651.0 -53700.0 -0.32 592282.0 74100.0 0.42 0.072 0.1361 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 M24 mock treatment 497681.0 42300.0 0.25 550416.0 32200.0 0.18 0.3078 0.9877 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N01 compound treatment 383162.0 -72200.0 -0.43 571133.0 52900.0 0.3 -0.0909 -0.1732 2065830 ICCB6_000287 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccc(Cl)cc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N02 compound treatment 254678.0 -201000.0 -1.19 581591.0 63400.0 0.36 -0.5895 -0.4726 2065831 ICCB6_000288 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N03 compound treatment 314511.0 -141000.0 -0.84 592773.0 74600.0 0.42 -0.2928 -0.3117 2065832 ICCB6_000289 C[Si](C)(F)C(CC(=O)c1ccccc1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N04 compound treatment 194003.0 -261000.0 -1.56 485091.0 -33100.0 -0.19 -1.2329 -0.787 2065833 ICCB6_000290 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N(C)OC)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N05 compound treatment 185346.0 -270000.0 -1.61 569893.0 51700.0 0.29 -0.9283 -0.5683 2065834 ICCB6_000291 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N06 compound treatment 40644.0 -415000.0 -2.47 87011.0 -431000.0 -2.45 -3.479 -1.0 2065835 ICCB6_000292 CC1(C)N[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC1CCC4=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N07 compound treatment 558981.0 104000.0 0.62 627335.0 109000.0 0.62 0.875 1.0 2065836 ICCB6_000293 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N08 compound treatment 187498.0 -268000.0 -1.59 244142.0 -274000.0 -1.56 -2.2292 -0.9999 2065837 ICCB6_000294 CN1[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N09 compound treatment 587102.0 132000.0 0.78 561652.0 43500.0 0.25 0.7292 0.8869 2065838 ICCB6_000295 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N10 compound treatment 309024.0 -146000.0 -0.87 519222.0 1030.0 0.01 -0.6116 -0.7024 2065839 ICCB6_000296 Cc1ccc(cc1)S(=O)(=O)N[C@H]2CC3CCC2(C)C3(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N11 compound treatment 585400.0 130000.0 0.77 613579.0 95400.0 0.54 0.9309 0.9849 2065840 ICCB6_000297 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N12 compound treatment 358511.0 -96800.0 -0.58 318297.0 -200000.0 -1.14 -1.2113 -0.9504 2065841 ICCB6_000298 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N13 compound treatment 247817.0 -208000.0 -1.24 490467.0 -27700.0 -0.16 -0.9848 -0.791 1952445 ICCB6_000299 Clc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc(CNC(=O)OCc5ccccc5)cc4)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N14 compound treatment 571251.0 116000.0 0.69 569084.0 50900.0 0.29 0.6924 0.9256 2065842 ICCB6_000300 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N15 compound treatment 511951.0 56600.0 0.34 539273.0 21100.0 0.12 0.323 0.9032 1952801 ICCB6_000301 Oc1ccccc1C#Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N16 compound treatment 481443.0 26100.0 0.16 447583.0 -70600.0 -0.4 -0.1741 -0.4043 2065843 ICCB6_000302 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N17 compound treatment 31378.0 -424000.0 -2.52 46427.0 -472000.0 -2.68 -3.6812 -0.9995 1952836 ICCB6_000303 CC(=O)c1ccc2oc(cc2c1)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N18 compound treatment 530991.0 75700.0 0.45 487661.0 -30500.0 -0.17 0.1956 0.4053 2065844 ICCB6_000304 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N19 compound treatment 545288.0 90000.0 0.54 517766.0 -430.0 0.0 0.3768 0.7039 1952631 ICCB6_000305 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N20 compound treatment 499357.0 44000.0 0.26 510582.0 -7610.0 -0.04 0.1546 0.5823 2065845 ICCB6_000306 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N21 compound treatment 528912.0 73600.0 0.44 477500.0 -40700.0 -0.23 0.146 0.2947 3005761 ICCB6_000307 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N22 compound treatment 557714.0 102000.0 0.61 471822.0 -46400.0 -0.26 0.2444 0.3681 2065846 ICCB6_000308 CN(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)Cc8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N23 mock treatment 538011.0 82700.0 0.49 533107.0 14900.0 0.08 0.4079 0.8169 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 N24 mock treatment 488525.0 33200.0 0.2 573132.0 54900.0 0.31 0.3606 0.9755 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O01 compound treatment 554430.0 99100.0 0.59 586422.0 68200.0 0.39 0.6914 0.9794 2065847 ICCB6_000309 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3cccc(F)c3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O02 compound treatment 498621.0 43300.0 0.26 568411.0 50200.0 0.29 0.3841 0.9987 3176588 ICCB6_000310 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)NCc5ccc(Cl)c(Cl)c5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O03 compound treatment 505143.0 49800.0 0.3 487580.0 -30600.0 -0.17 0.0865 0.2516 2065848 ICCB6_000311 Cc1ccc(cc1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O04 compound treatment 505237.0 49900.0 0.3 543079.0 24900.0 0.14 0.3101 0.9425 3176589 ICCB6_000312 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCc5ccc(cc5)[N+](=O)[O-])c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O05 compound treatment 546802.0 91500.0 0.54 623117.0 105000.0 0.6 0.8068 0.999 2065849 ICCB6_000313 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)CCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O06 compound treatment 433061.0 -22300.0 -0.13 399966.0 -118000.0 -0.67 -0.5692 -0.8305 2065850 ICCB6_000314 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(Br)cc4)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O07 compound treatment 616093.0 161000.0 0.96 598090.0 79900.0 0.45 0.9978 0.9421 2065851 ICCB6_000315 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O08 compound treatment 528585.0 73200.0 0.44 491081.0 -27100.0 -0.15 0.1992 0.4308 2065852 ICCB6_000316 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(cc4)[N+](=O)[O-])cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O09 compound treatment 578076.0 123000.0 0.73 662416.0 144000.0 0.82 1.0964 0.9983 2065853 ICCB6_000317 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O10 compound treatment 418723.0 -36600.0 -0.22 538093.0 19900.0 0.11 -0.0741 -0.3017 2065854 ICCB6_000318 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O11 compound treatment 587995.0 133000.0 0.79 547838.0 29600.0 0.17 0.6775 0.8392 2065855 ICCB6_000319 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O12 compound treatment 491981.0 36600.0 0.22 437649.0 -80500.0 -0.46 -0.1697 -0.3345 2065856 ICCB6_000320 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O13 compound treatment 581616.0 126000.0 0.75 557399.0 39200.0 0.22 0.6891 0.879 1952450 ICCB6_000321 CCOC(=O)C(O)C(O)c1ccc(CO[Si](C(C)C)(C(C)C)c2ccccc2)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O14 compound treatment 361237.0 -94100.0 -0.56 355707.0 -162000.0 -0.92 -1.0494 -0.9712 2065857 ICCB6_000322 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O15 compound treatment 481018.0 25700.0 0.15 442867.0 -75300.0 -0.43 -0.1948 -0.4284 1952761 ICCB6_000323 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O16 compound treatment 156839.0 -298000.0 -1.78 156275.0 -362000.0 -2.06 -2.7115 -0.9973 2065858 ICCB6_000324 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O17 compound treatment 67331.0 -388000.0 -2.31 52502.0 -466000.0 -2.65 -3.5055 -0.9977 1952837 ICCB6_000325 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O18 compound treatment 313989.0 -141000.0 -0.84 181957.0 -336000.0 -1.91 -1.9469 -0.932 2065859 ICCB6_000326 CO[C@H]1O[C@@H]2COC(O[C@H]2[C@H](OC(=O)/C=C/C=C/C)[C@H]1OC(=O)/C=C/C=C/C)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O19 compound treatment 58010.0 -397000.0 -2.36 60087.0 -458000.0 -2.61 -3.5142 -0.9988 1952633 ICCB6_000327 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O20 compound treatment 497899.0 42600.0 0.25 443528.0 -74700.0 -0.42 -0.1211 -0.245 2065860 ICCB6_000328 CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COC(c2ccccc2)(c3ccccc3)c4ccccc4)O[C@H](CC=C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1N=[N+]=[N-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O21 compound treatment 546246.0 90900.0 0.54 456773.0 -61400.0 -0.35 0.1356 0.2105 1952755 ICCB6_000329 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O22 compound treatment 501734.0 46400.0 0.28 599175.0 81000.0 0.46 0.5209 0.9701 2065861 ICCB6_000330 C[C@H]1[C@H](OC(=O)N1C(=O)[C@@H](CC=C)C(C)(C)C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O23 mock treatment 317548.0 -138000.0 -0.82 504643.0 -13600.0 -0.08 -0.6344 -0.7702 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 O24 mock treatment 540645.0 85300.0 0.51 531408.0 13200.0 0.08 0.4121 0.803 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P01 compound treatment 221424.0 -234000.0 -1.39 266793.0 -251000.0 -1.43 -1.9953 -0.9999 2065862 ICCB6_000331 CC1(C)OCC2=C(CC(CCc3ccccc3)OC2CCc4ccccc4)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P02 compound treatment 538257.0 82900.0 0.49 596283.0 78100.0 0.44 0.6629 0.9986 2065863 ICCB6_000332 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P03 compound treatment 563840.0 109000.0 0.65 523505.0 5310.0 0.03 0.478 0.7394 2065864 ICCB6_000333 C1CCC(CC1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P04 compound treatment 482717.0 27400.0 0.16 519864.0 1670.0 0.01 0.1219 0.747 2065865 ICCB6_000334 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P05 compound treatment 560572.0 105000.0 0.63 616663.0 98500.0 0.56 0.8388 0.9984 2065866 ICCB6_000335 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P06 compound treatment 270011.0 -185000.0 -1.1 341942.0 -176000.0 -1.0 -1.4886 -0.9989 2065867 ICCB6_000336 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P07 compound treatment 521335.0 66000.0 0.39 508121.0 -10100.0 -0.06 0.2372 0.5976 2065868 ICCB6_000337 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P08 compound treatment 455955.0 618.0 0.0 476055.0 -42100.0 -0.24 -0.1669 -0.6962 2065869 ICCB6_000338 C[C@H](Cc1ccccc1)N(C)CC#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P09 compound treatment 478216.0 22900.0 0.14 572389.0 54200.0 0.31 0.3142 0.9326 2065870 ICCB6_000339 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P10 compound treatment 451429.0 -3910.0 -0.02 500048.0 -18100.0 -0.1 -0.0894 -0.8453 2065871 ICCB6_000340 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P11 compound treatment 105286.0 -350000.0 -2.08 73223.0 -445000.0 -2.53 -3.2624 -0.9953 2065872 ICCB6_000341 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P12 compound treatment 541935.0 86600.0 0.52 445289.0 -72900.0 -0.41 0.0713 0.1077 2065873 ICCB6_000342 CCOC(OCC)C#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P13 compound treatment 466979.0 11600.0 0.07 572117.0 53900.0 0.31 0.2658 0.8456 2065874 ICCB6_000343 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P14 compound treatment 69583.0 -386000.0 -2.3 59046.0 -459000.0 -2.61 -3.4697 -0.9979 2065875 ICCB6_000344 Brc1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P15 compound treatment 554712.0 99400.0 0.59 497658.0 -20500.0 -0.12 0.3356 0.5567 1952804 ICCB6_000345 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P16 compound treatment 64970.0 -390000.0 -2.32 64818.0 -453000.0 -2.58 -3.4659 -0.9986 2065876 ICCB6_000346 CCOC(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P17 compound treatment 287995.0 -167000.0 -1.0 192681.0 -326000.0 -1.85 -2.0132 -0.9577 1952838 ICCB6_000347 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P18 compound treatment 53203.0 -402000.0 -2.39 52152.0 -466000.0 -2.65 -3.5663 -0.9987 2065877 ICCB6_000348 O=C(/C=C\1/C(=O)Nc2ccccc12)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P19 compound treatment 61289.0 -394000.0 -2.35 50336.0 -468000.0 -2.66 -3.5396 -0.998 1952634 ICCB6_000349 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P20 compound treatment 63923.0 -391000.0 -2.33 52115.0 -466000.0 -2.65 -3.5214 -0.9979 2065878 ICCB6_000350 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P21 compound treatment 610710.0 155000.0 0.92 544921.0 26700.0 0.15 0.7613 0.8124 1952770 ICCB6_000351 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P22 compound treatment 68396.0 -387000.0 -2.3 57721.0 -460000.0 -2.62 -3.48 -0.9979 2065879 ICCB6_000352 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P23 mock treatment 585659.0 130000.0 0.78 499043.0 -19200.0 -0.11 0.4714 0.6019 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.1463 P24 mock treatment 574888.0 120000.0 0.71 571936.0 53700.0 0.31 0.7192 0.9288 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A01 mock treatment 516188.0 -7110.0 -0.04 470571.0 -32200.0 -0.18 -0.1593 -0.8482 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A02 mock treatment 475181.0 -48100.0 -0.29 468533.0 -34200.0 -0.19 -0.3401 -0.9823 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A03 compound treatment 582962.0 59700.0 0.36 607786.0 105000.0 0.6 0.6734 0.9692 3000673 BCB01_000001 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A04 compound treatment 545029.0 21700.0 0.13 348579.0 -154000.0 -0.88 -0.5285 -0.5963 3000674 BCB01_000002 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A05 compound treatment 518228.0 -5070.0 -0.03 422395.0 -80400.0 -0.46 -0.3445 -0.7521 3000675 BCB01_000003 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A06 compound treatment 482780.0 -40500.0 -0.24 518078.0 15300.0 0.09 -0.1089 -0.4247 3000676 BCB01_000004 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A07 compound treatment 463032.0 -60300.0 -0.36 561064.0 58300.0 0.33 -0.0191 -0.0392 3093034 BCB01_000005 COc1cc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A08 compound treatment 293311.0 -230000.0 -1.37 310683.0 -192000.0 -1.09 -1.7402 -0.9937 3000677 BCB01_000006 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A09 compound treatment 412813.0 -110000.0 -0.66 399376.0 -103000.0 -0.59 -0.8807 -0.9984 3093035 BCB01_000007 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A10 compound treatment 377411.0 -146000.0 -0.87 374505.0 -128000.0 -0.73 -1.1296 -0.9962 3000678 BCB01_000008 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A11 compound treatment 466325.0 -57000.0 -0.34 454460.0 -48300.0 -0.27 -0.434 -0.9945 3093104 BCB01_000009 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A12 compound treatment 279289.0 -244000.0 -1.45 495076.0 -7680.0 -0.04 -1.0577 -0.728 3093105 BCB01_000010 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A13 compound treatment 552398.0 29100.0 0.17 485014.0 -17700.0 -0.1 0.0511 0.255 3000679 BCB01_000011 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A14 compound treatment 520704.0 -2590.0 -0.02 471398.0 -31400.0 -0.18 -0.137 -0.7654 3093106 BCB01_000012 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A15 compound treatment 64823.0 -458000.0 -2.73 31038.0 -472000.0 -2.68 -3.8262 -1.0 3093107 BCB01_000013 CCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A16 compound treatment 454113.0 -69200.0 -0.41 456759.0 -46000.0 -0.26 -0.4761 -0.976 3000680 BCB01_000014 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A17 compound treatment 451822.0 -71500.0 -0.43 244553.0 -258000.0 -1.47 -1.3391 -0.8759 3093108 BCB01_000015 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A18 compound treatment 467889.0 -55400.0 -0.33 421767.0 -81000.0 -0.46 -0.5588 -0.9866 3093109 BCB01_000016 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A19 compound treatment 533292.0 10000.0 0.06 474896.0 -27900.0 -0.16 -0.07 -0.4134 3000681 BCB01_000017 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A20 compound treatment 584449.0 61200.0 0.36 556292.0 53500.0 0.3 0.4726 0.9961 3093110 BCB01_000018 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A21 compound treatment 677828.0 155000.0 0.92 426897.0 -75900.0 -0.43 0.3453 0.3399 3000682 BCB01_000019 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A22 compound treatment 535295.0 12000.0 0.07 592094.0 89300.0 0.51 0.4097 0.7986 3093111 BCB01_000020 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A23 mock treatment 674386.0 151000.0 0.9 535020.0 32300.0 0.18 0.7656 0.8342 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 A24 mock treatment 574054.0 50800.0 0.3 504202.0 1440.0 0.01 0.2194 0.7261 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B01 mock treatment 544892.0 21600.0 0.13 700520.0 198000.0 1.12 0.8861 0.7828 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B02 mock treatment 504016.0 -19300.0 -0.11 576942.0 74200.0 0.42 0.2172 0.4967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B03 compound treatment 634035.0 111000.0 0.66 571218.0 68500.0 0.39 0.7413 0.9685 3093112 BCB01_000021 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B04 compound treatment 563117.0 39800.0 0.24 576223.0 73500.0 0.42 0.463 0.9639 3000683 BCB01_000022 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B05 compound treatment 220028.0 -303000.0 -1.8 157292.0 -345000.0 -1.96 -2.6654 -0.9991 3093113 BCB01_000023 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B06 compound treatment 470617.0 -52700.0 -0.31 605731.0 103000.0 0.59 0.1924 0.2896 3093114 BCB01_000024 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B07 compound treatment 121939.0 -401000.0 -2.39 77789.0 -425000.0 -2.42 -3.3979 -1.0 3000684 BCB01_000025 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B08 compound treatment 502419.0 -20900.0 -0.12 493855.0 -8900.0 -0.05 -0.1237 -0.9217 3093115 BCB01_000026 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B09 compound treatment 468459.0 -54800.0 -0.33 457065.0 -45700.0 -0.26 -0.4145 -0.9936 3093116 BCB01_000027 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B10 compound treatment 497053.0 -26200.0 -0.16 530136.0 27400.0 0.16 -3.0E-4 -0.0016 3000685 BCB01_000028 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B11 compound treatment 463333.0 -60000.0 -0.36 563010.0 60300.0 0.34 -0.0101 -0.0203 3093117 BCB01_000029 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(C)cc(C)cc4C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B12 compound treatment 71961.0 -451000.0 -2.69 51255.0 -452000.0 -2.57 -3.7149 -0.9997 3093118 BCB01_000030 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B13 compound treatment 467576.0 -55700.0 -0.33 527304.0 24500.0 0.14 -0.1358 -0.3774 3000686 BCB01_000031 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B14 compound treatment 403686.0 -120000.0 -0.71 236715.0 -266000.0 -1.51 -1.5731 -0.9409 3093119 BCB01_000032 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B15 compound treatment 460860.0 -62400.0 -0.37 435013.0 -67700.0 -0.39 -0.5352 -0.9998 3093120 BCB01_000033 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(c4ccccc4)c5ccccc5)C(=O)N(C3=O)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B16 compound treatment 377016.0 -146000.0 -0.87 269869.0 -233000.0 -1.32 -1.5521 -0.9793 3000687 BCB01_000034 CCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B17 compound treatment 533445.0 10100.0 0.06 470459.0 -32300.0 -0.18 -0.0872 -0.4508 3000688 BCB01_000035 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B18 compound treatment 51833.0 -471000.0 -2.81 51814.0 -451000.0 -2.56 -3.7974 -0.999 3093121 BCB01_000036 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B19 compound treatment 518798.0 -4500.0 -0.03 409839.0 -92900.0 -0.53 -0.3926 -0.742 3093122 BCB01_000037 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B20 compound treatment 208853.0 -314000.0 -1.87 115477.0 -387000.0 -2.2 -2.8806 -0.9967 3093123 BCB01_000038 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B21 compound treatment 391819.0 -131000.0 -0.78 423690.0 -79100.0 -0.45 -0.8712 -0.9654 3000689 BCB01_000039 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B22 compound treatment 53494.0 -470000.0 -2.8 48521.0 -454000.0 -2.58 -3.8036 -0.9992 3093124 BCB01_000040 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B23 mock treatment 480040.0 -43300.0 -0.26 418452.0 -84300.0 -0.48 -0.521 -0.9575 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 B24 mock treatment 637629.0 114000.0 0.68 453216.0 -49500.0 -0.28 0.2819 0.3828 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C01 mock treatment 501029.0 -22300.0 -0.13 524473.0 21700.0 0.12 -0.0064 -0.0352 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C02 mock treatment 492293.0 -31000.0 -0.18 480832.0 -21900.0 -0.12 -0.2186 -0.9818 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C03 compound treatment 476057.0 -47200.0 -0.28 515697.0 12900.0 0.07 -0.1468 -0.505 3000690 BCB01_000041 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C04 compound treatment 441984.0 -81300.0 -0.48 481647.0 -21100.0 -0.12 -0.4271 -0.8566 3093125 BCB01_000042 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C05 compound treatment 478414.0 -44900.0 -0.27 500804.0 -1950.0 -0.01 -0.1967 -0.7359 3093282 BCB01_000043 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C06 compound treatment 429555.0 -93700.0 -0.56 469478.0 -33300.0 -0.19 -0.5283 -0.8968 3000691 BCB01_000044 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C07 compound treatment 282592.0 -241000.0 -1.43 508774.0 6020.0 0.03 -0.9888 -0.69 3093194 BCB01_000045 COc1cc(NN2C3C(C=CC2C(O)C4CCC(CC4)C(=C)C)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C08 compound treatment 309927.0 -213000.0 -1.27 409029.0 -93700.0 -0.53 -1.2748 -0.9257 3093195 BCB01_000046 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C09 compound treatment 551051.0 27800.0 0.17 481666.0 -21100.0 -0.12 0.032 0.1567 3000692 BCB01_000047 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C10 compound treatment 140765.0 -383000.0 -2.28 463527.0 -39200.0 -0.22 -1.7676 -0.7727 3093196 BCB01_000048 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C11 compound treatment 60734.0 -463000.0 -2.75 43014.0 -460000.0 -2.61 -3.7953 -0.9997 3093197 BCB01_000049 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C12 compound treatment 434619.0 -88700.0 -0.53 481208.0 -21500.0 -0.12 -0.4598 -0.8487 3000693 BCB01_000050 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C13 compound treatment 485644.0 -37700.0 -0.22 194898.0 -308000.0 -1.75 -1.3964 -0.7912 3093198 BCB01_000051 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C14 compound treatment 414092.0 -109000.0 -0.65 517502.0 14700.0 0.08 -0.4003 -0.6108 3000694 BCB01_000052 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C15 compound treatment 438760.0 -84500.0 -0.5 461696.0 -41100.0 -0.23 -0.5209 -0.9391 3093199 BCB01_000053 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C16 compound treatment 66852.0 -456000.0 -2.72 60904.0 -442000.0 -2.51 -3.6976 -0.9992 3093200 BCB01_000054 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C17 compound treatment 551831.0 28500.0 0.17 505201.0 2440.0 0.01 0.1299 0.7624 3000695 BCB01_000055 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C18 compound treatment 489809.0 -33500.0 -0.2 457313.0 -45400.0 -0.26 -0.3237 -0.9918 3093201 BCB01_000056 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C19 compound treatment 556127.0 32800.0 0.2 540798.0 38000.0 0.22 0.2911 0.9987 3093202 BCB01_000057 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C20 compound treatment 517867.0 -5430.0 -0.03 457022.0 -45700.0 -0.26 -0.2068 -0.7889 3000696 BCB01_000058 COc1ccc(cc1)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C21 compound treatment 568175.0 44900.0 0.27 464616.0 -38100.0 -0.22 0.0355 0.1032 3093203 BCB01_000059 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C22 compound treatment 546999.0 23700.0 0.14 537915.0 35200.0 0.2 0.2411 0.9854 3093204 BCB01_000060 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C23 mock treatment 529612.0 6320.0 0.04 97659.0 -405000.0 -2.3 -1.6024 -0.6955 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 C24 mock treatment 530895.0 7600.0 0.05 423965.0 -78800.0 -0.45 -0.2849 -0.6325 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D01 mock treatment 509426.0 -13900.0 -0.08 617222.0 114000.0 0.65 0.4019 0.6125 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D02 mock treatment 416072.0 -107000.0 -0.64 487277.0 -15500.0 -0.09 -0.5135 -0.7971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D03 compound treatment 457408.0 -65900.0 -0.39 507074.0 4320.0 0.02 -0.2599 -0.6615 3000697 BCB01_000061 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccc(O)c4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D04 compound treatment 83112.0 -440000.0 -2.62 113991.0 -389000.0 -2.21 -3.4157 -0.9964 3093205 BCB01_000062 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D05 compound treatment 455204.0 -68100.0 -0.41 431969.0 -70800.0 -0.4 -0.5712 -1.0 3093206 BCB01_000063 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)B(O)O)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D06 compound treatment 414162.0 -109000.0 -0.65 470730.0 -32000.0 -0.18 -0.5881 -0.8718 3000698 BCB01_000064 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D07 compound treatment 446383.0 -76900.0 -0.46 377060.0 -126000.0 -0.71 -0.8291 -0.9768 3093207 BCB01_000065 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cn(C(=O)C)c5ccccc45)C(=O)N(C3=O)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D08 compound treatment 481878.0 -41400.0 -0.25 438362.0 -64400.0 -0.37 -0.4332 -0.9814 3000792 BCB01_000066 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D09 compound treatment 381977.0 -141000.0 -0.84 376077.0 -127000.0 -0.72 -1.1041 -0.997 3000794 BCB01_000067 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(C)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D10 compound treatment 69882.0 -453000.0 -2.7 58968.0 -444000.0 -2.52 -3.6926 -0.9994 3000796 BCB01_000068 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D11 compound treatment 322745.0 -201000.0 -1.19 360911.0 -142000.0 -0.81 -1.4144 -0.9818 3000797 BCB01_000069 CC(C)c1ccc(NN2C3C(C=CC2C(O)CC(C)c4ccc(C)o4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D12 compound treatment 75003.0 -448000.0 -2.67 67301.0 -435000.0 -2.48 -3.6376 -0.9993 3093208 BCB01_000070 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4c(F)cccc4Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D13 compound treatment 471870.0 -51400.0 -0.31 397547.0 -105000.0 -0.6 -0.6395 -0.9515 3093209 BCB01_000071 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccs4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D14 compound treatment 78659.0 -445000.0 -2.65 69341.0 -433000.0 -2.46 -3.614 -0.9994 3000798 BCB01_000072 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D15 compound treatment 394038.0 -129000.0 -0.77 375122.0 -128000.0 -0.73 -1.0572 -0.9996 3093210 BCB01_000073 CC(C)c1ccc(NN2C3C(C=CC2C(O)Cc4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D16 compound treatment 101721.0 -422000.0 -2.51 86182.0 -417000.0 -2.37 -3.4492 -0.9996 3000800 BCB01_000074 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D17 compound treatment 459658.0 -63600.0 -0.38 494070.0 -8690.0 -0.05 -0.3027 -0.7926 3093211 BCB01_000075 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D18 compound treatment 78476.0 -445000.0 -2.65 93825.0 -409000.0 -2.33 -3.5163 -0.9979 3000876 BCB01_000076 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c(C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D19 compound treatment 423410.0 -99900.0 -0.59 380824.0 -122000.0 -0.69 -0.9107 -0.9971 3000877 BCB01_000077 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc5OCOc5c4)C(=O)N(C3=O)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D20 compound treatment 168585.0 -355000.0 -2.11 144866.0 -358000.0 -2.04 -2.9319 -0.9998 3000878 BCB01_000078 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D21 compound treatment 442642.0 -80700.0 -0.48 298862.0 -204000.0 -1.16 -1.1593 -0.9238 3000880 BCB01_000079 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4=C[C@H]5C[C@@H](C4)C5(C)C)C(=O)N(C3=O)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D22 compound treatment 350121.0 -173000.0 -1.03 317224.0 -186000.0 -1.06 -1.4748 -0.9999 3093212 BCB01_000080 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D23 mock treatment 529608.0 6310.0 0.04 465985.0 -36800.0 -0.21 -0.1213 -0.5709 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 D24 mock treatment 497120.0 -26200.0 -0.16 484730.0 -18000.0 -0.1 -0.1826 -0.9794 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E01 mock treatment 543160.0 19900.0 0.12 354769.0 -148000.0 -0.84 -0.5115 -0.6019 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E02 mock treatment 443581.0 -79700.0 -0.47 438373.0 -64400.0 -0.37 -0.5944 -0.9918 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E03 compound treatment 289960.0 -233000.0 -1.39 485343.0 -17400.0 -0.1 -1.052 -0.7556 3000882 BCB01_000081 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E04 compound treatment 502833.0 -20500.0 -0.12 483759.0 -19000.0 -0.11 -0.1625 -0.9982 3093213 BCB01_000082 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E05 compound treatment 363114.0 -160000.0 -0.95 331041.0 -172000.0 -0.98 -1.3646 -0.9999 3093214 BCB01_000083 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E06 compound treatment 339904.0 -183000.0 -1.09 524720.0 22000.0 0.12 -0.6835 -0.6221 3000884 BCB01_000084 CN1C(=O)C2C=CC(C(O)C3CCC(CC3)C(=C)C)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E07 compound treatment 190506.0 -333000.0 -1.98 518700.0 15900.0 0.09 -1.3364 -0.674 3093215 BCB01_000085 CN1C(=O)C2C=CC(C(O)c3ccco3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E08 compound treatment 473976.0 -49300.0 -0.29 372784.0 -130000.0 -0.74 -0.7302 -0.9182 3093216 BCB01_000086 CCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E09 compound treatment 225102.0 -298000.0 -1.77 494320.0 -8440.0 -0.05 -1.2888 -0.726 3000885 BCB01_000087 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E10 compound treatment 60448.0 -463000.0 -2.75 169284.0 -333000.0 -1.9 -3.2887 -0.9834 3093283 BCB01_000088 CCCCCCCCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E11 compound treatment 65994.0 -457000.0 -2.72 23658.0 -479000.0 -2.72 -3.851 -1.0 3093284 BCB01_000089 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E12 compound treatment 340650.0 -183000.0 -1.09 431737.0 -71000.0 -0.4 -1.0542 -0.9091 3000886 BCB01_000090 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E13 compound treatment 411890.0 -111000.0 -0.66 165758.0 -337000.0 -1.92 -1.824 -0.8994 3093285 BCB01_000091 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E14 compound treatment 517955.0 -5340.0 -0.03 473036.0 -29700.0 -0.17 -0.142 -0.8256 3093286 BCB01_000092 COc1ccc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c5ccccc15 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E15 compound treatment 398802.0 -124000.0 -0.74 89879.0 -413000.0 -2.35 -2.1842 -0.8871 3000889 BCB01_000093 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E16 compound treatment 424271.0 -99000.0 -0.59 187981.0 -315000.0 -1.79 -1.6825 -0.8928 3093287 BCB01_000094 COc1cc(Br)cc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E17 compound treatment 497480.0 -25800.0 -0.15 472564.0 -30200.0 -0.17 -0.2301 -0.9985 3093288 BCB01_000095 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E18 compound treatment 477937.0 -45400.0 -0.27 488128.0 -14600.0 -0.08 -0.2497 -0.884 3000890 BCB01_000096 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3N5CCCCC5)C(=O)N(C)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E19 compound treatment 471390.0 -51900.0 -0.31 480143.0 -22600.0 -0.13 -0.3094 -0.9246 3093289 BCB01_000097 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E20 compound treatment 475195.0 -48100.0 -0.29 497294.0 -5460.0 -0.03 -0.2244 -0.7793 3093290 BCB01_000098 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E21 compound treatment 443262.0 -80000.0 -0.48 35834.0 -467000.0 -2.66 -2.2144 -0.8208 3000891 BCB01_000099 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E22 compound treatment 460143.0 -63200.0 -0.38 315031.0 -188000.0 -1.07 -1.0206 -0.9018 3093291 BCB01_000100 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E23 mock treatment 483179.0 -40100.0 -0.24 190092.0 -313000.0 -1.78 -1.4261 -0.7949 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 E24 mock treatment 548936.0 25600.0 0.15 225635.0 -277000.0 -1.58 -1.0064 -0.6357 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F01 mock treatment 626419.0 103000.0 0.61 542258.0 39500.0 0.22 0.5928 0.9071 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F02 mock treatment 488567.0 -34700.0 -0.21 472161.0 -30600.0 -0.17 -0.2692 -0.9963 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F03 compound treatment 563088.0 39800.0 0.24 487215.0 -15500.0 -0.09 0.105 0.4152 3093292 BCB01_000101 CC(C)c1ccc(NN2C3C(C=CC2C(O)/C=C(\C)/CCC=C(C)C)C(=O)N(C3=O)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F04 compound treatment 71571.0 -452000.0 -2.69 53923.0 -449000.0 -2.55 -3.7058 -0.9997 3000892 BCB01_000102 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F05 compound treatment 351653.0 -172000.0 -1.02 442476.0 -60300.0 -0.34 -0.9647 -0.8953 3093293 BCB01_000103 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F06 compound treatment 78050.0 -445000.0 -2.65 46674.0 -456000.0 -2.59 -3.7077 -0.9999 3000894 BCB01_000104 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F07 compound treatment 520656.0 -2640.0 -0.02 497015.0 -5740.0 -0.03 -0.0342 -0.9438 3093294 BCB01_000105 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F08 compound treatment 466571.0 -56700.0 -0.34 346770.0 -156000.0 -0.89 -0.866 -0.9124 3093295 BCB01_000106 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F09 compound treatment 336822.0 -186000.0 -1.11 153873.0 -349000.0 -1.98 -2.1877 -0.9623 3000896 BCB01_000107 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F10 compound treatment 318270.0 -205000.0 -1.22 372926.0 -130000.0 -0.74 -1.3849 -0.971 3093296 BCB01_000108 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F11 compound treatment 423200.0 -100000.0 -0.6 438015.0 -64700.0 -0.37 -0.6816 -0.9732 3093297 BCB01_000109 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)C(=O)C)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F12 compound treatment 403389.0 -120000.0 -0.71 457336.0 -45400.0 -0.26 -0.6872 -0.9056 3000898 BCB01_000110 CC(C)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F13 compound treatment 51549.0 -472000.0 -2.81 25323.0 -477000.0 -2.72 -3.9051 -0.9999 3000979 BCB01_000111 CCCCCCCCCCC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F14 compound treatment 109378.0 -414000.0 -2.46 182990.0 -320000.0 -1.82 -3.0277 -0.9888 3000980 BCB01_000112 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc(O)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F15 compound treatment 170604.0 -353000.0 -2.1 171278.0 -331000.0 -1.89 -2.8172 -0.9986 3000981 BCB01_000113 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F16 compound treatment 330371.0 -193000.0 -1.15 301190.0 -202000.0 -1.15 -1.6224 -1.0 3000982 BCB01_000114 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F17 compound treatment 561579.0 38300.0 0.23 507510.0 4750.0 0.03 0.1802 0.7855 3000984 BCB01_000115 COc1ccc(C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O)c4ccccc14 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F18 compound treatment 569288.0 46000.0 0.27 65248.0 -438000.0 -2.49 -1.5657 -0.6255 3093298 BCB01_000116 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F19 compound treatment 435212.0 -88100.0 -0.52 448096.0 -54700.0 -0.31 -0.5905 -0.9689 3093299 BCB01_000117 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F20 compound treatment 471769.0 -51500.0 -0.31 444369.0 -58400.0 -0.33 -0.4516 -0.9992 3000987 BCB01_000118 CC(=O)N1CC(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F21 compound treatment 472992.0 -50300.0 -0.3 432256.0 -70500.0 -0.4 -0.4952 -0.9897 3093300 BCB01_000119 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F22 compound treatment 282356.0 -241000.0 -1.43 329633.0 -173000.0 -0.98 -1.7101 -0.9832 3093301 BCB01_000120 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F23 mock treatment 453200.0 -70100.0 -0.42 131759.0 -371000.0 -2.11 -1.7868 -0.8308 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 F24 mock treatment 560076.0 36800.0 0.22 443362.0 -59400.0 -0.34 -0.0841 -0.2088 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G01 mock treatment 548775.0 25500.0 0.15 557130.0 54400.0 0.31 0.3259 0.9462 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G02 mock treatment 478138.0 -45200.0 -0.27 475216.0 -27500.0 -0.16 -0.3008 -0.967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G03 compound treatment 531908.0 8610.0 0.05 434179.0 -68600.0 -0.39 -0.2395 -0.6089 3000990 BCB01_000121 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G04 compound treatment 380096.0 -143000.0 -0.85 555803.0 53000.0 0.3 -0.3893 -0.4306 3093302 BCB01_000122 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G05 compound treatment 550083.0 26800.0 0.16 514656.0 11900.0 0.07 0.1606 0.9272 3093303 BCB01_000123 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G06 compound treatment 491859.0 -31400.0 -0.19 479605.0 -23200.0 -0.13 -0.2254 -0.9852 3000991 BCB01_000124 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G07 compound treatment 455019.0 -68300.0 -0.41 458121.0 -44600.0 -0.25 -0.4668 -0.9743 3093304 BCB01_000125 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G08 compound treatment 423559.0 -99700.0 -0.59 461166.0 -41600.0 -0.24 -0.587 -0.9186 3000992 BCB01_000126 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G09 compound treatment 484982.0 -38300.0 -0.23 467085.0 -35700.0 -0.2 -0.3047 -0.9983 3093373 BCB01_000127 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G10 compound treatment 472462.0 -50800.0 -0.3 468580.0 -34200.0 -0.19 -0.3514 -0.9771 3093374 BCB01_000128 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G11 compound treatment 476927.0 -46400.0 -0.28 515589.0 12800.0 0.07 -0.1435 -0.5029 3000993 BCB01_000129 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G12 compound treatment 341767.0 -182000.0 -1.08 392518.0 -110000.0 -0.63 -1.2072 -0.9665 3093375 BCB01_000130 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(C2C1=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G13 compound treatment 431842.0 -91500.0 -0.54 435446.0 -67300.0 -0.38 -0.6555 -0.9852 3093376 BCB01_000131 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G14 compound treatment 420659.0 -103000.0 -0.61 432666.0 -70100.0 -0.4 -0.7138 -0.9786 3000994 BCB01_000132 C/C=C/C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G15 compound treatment 325333.0 -198000.0 -1.18 376368.0 -126000.0 -0.72 -1.3413 -0.9719 3093377 BCB01_000133 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G16 compound treatment 428571.0 -94700.0 -0.56 439927.0 -62800.0 -0.36 -0.6513 -0.9758 3000995 BCB01_000134 CCC(CC)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G17 compound treatment 501507.0 -21800.0 -0.13 490168.0 -12600.0 -0.07 -0.1423 -0.9608 3093378 BCB01_000135 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G18 compound treatment 421057.0 -102000.0 -0.61 460145.0 -42600.0 -0.24 -0.6016 -0.9186 3000996 BCB01_000136 CC(C)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G19 compound treatment 489980.0 -33300.0 -0.2 463274.0 -39500.0 -0.22 -0.299 -0.9981 3093379 BCB01_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G20 compound treatment 469388.0 -53900.0 -0.32 527819.0 25100.0 0.14 -0.1261 -0.3592 3093380 BCB01_000138 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G21 compound treatment 451274.0 -72000.0 -0.43 196388.0 -306000.0 -1.74 -1.535 -0.8556 3000997 BCB01_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G22 compound treatment 348145.0 -175000.0 -1.04 211113.0 -292000.0 -1.66 -1.9098 -0.975 3093381 BCB01_000140 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G23 mock treatment 528981.0 5680.0 0.03 128748.0 -374000.0 -2.13 -1.48 -0.6958 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 G24 mock treatment 508825.0 -14500.0 -0.09 478411.0 -24300.0 -0.14 -0.1588 -0.9739 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H01 mock treatment 507940.0 -15400.0 -0.09 537079.0 34300.0 0.2 0.0734 0.3405 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H02 mock treatment 467500.0 -55800.0 -0.33 508613.0 5860.0 0.03 -0.2113 -0.633 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H03 compound treatment 537164.0 13900.0 0.08 567542.0 64800.0 0.37 0.3189 0.8446 3000998 BCB01_000141 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H04 compound treatment 342768.0 -181000.0 -1.07 445878.0 -56900.0 -0.32 -0.9884 -0.8809 3093382 BCB01_000142 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H05 compound treatment 473262.0 -50000.0 -0.3 503430.0 673.0 0.0 -0.2079 -0.698 3093383 BCB01_000143 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H06 compound treatment 475091.0 -48200.0 -0.29 453949.0 -48800.0 -0.28 -0.3991 -0.9999 3000999 BCB01_000144 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(C#N)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H07 compound treatment 550141.0 26800.0 0.16 535411.0 32700.0 0.19 0.2443 0.9972 3093384 BCB01_000145 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H08 compound treatment 239214.0 -284000.0 -1.69 199905.0 -303000.0 -1.72 -2.4133 -1.0 3093385 BCB01_000146 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H09 compound treatment 260096.0 -263000.0 -1.57 164794.0 -338000.0 -1.92 -2.4666 -0.9948 3001000 BCB01_000147 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H10 compound treatment 65757.0 -458000.0 -2.72 53944.0 -449000.0 -2.55 -3.7302 -0.9995 3001068 BCB01_000148 CC1(C)[C@H]2CC1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H11 compound treatment 461913.0 -61400.0 -0.37 505368.0 2610.0 0.01 -0.2478 -0.6778 3001069 BCB01_000149 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H12 compound treatment 297079.0 -226000.0 -1.35 193846.0 -309000.0 -1.76 -2.1942 -0.9914 3001070 BCB01_000150 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H13 compound treatment 455124.0 -68200.0 -0.41 486109.0 -16600.0 -0.09 -0.3538 -0.8493 3001072 BCB01_000151 C/C=C/C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H14 compound treatment 61399.0 -462000.0 -2.75 51442.0 -451000.0 -2.57 -3.7586 -0.9994 3093386 BCB01_000152 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H15 compound treatment 551600.0 28300.0 0.17 454134.0 -48600.0 -0.28 -0.0764 -0.236 3001073 BCB01_000153 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H16 compound treatment 464571.0 -58700.0 -0.35 419048.0 -83700.0 -0.48 -0.5837 -0.9885 3093387 BCB01_000154 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H17 compound treatment 368684.0 -155000.0 -0.92 421318.0 -81400.0 -0.46 -0.9781 -0.9495 3093388 BCB01_000155 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H18 compound treatment 453770.0 -69500.0 -0.41 421650.0 -81100.0 -0.46 -0.6187 -0.9985 3001076 BCB01_000156 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(I)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H19 compound treatment 484263.0 -39000.0 -0.23 446322.0 -56400.0 -0.32 -0.3912 -0.9874 3093389 BCB01_000157 CC(C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H20 compound treatment 473921.0 -49400.0 -0.29 432077.0 -70700.0 -0.4 -0.492 -0.9881 3093390 BCB01_000158 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H21 compound treatment 532236.0 8940.0 0.05 445371.0 -57400.0 -0.33 -0.1931 -0.5841 3001078 BCB01_000159 CC(CC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccc(C)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H22 compound treatment 451122.0 -72200.0 -0.43 421164.0 -81600.0 -0.46 -0.6318 -0.9993 3093391 BCB01_000160 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H23 mock treatment 528034.0 4740.0 0.03 489756.0 -13000.0 -0.07 -0.0323 -0.4087 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 H24 mock treatment 498086.0 -25200.0 -0.15 487688.0 -15100.0 -0.09 -0.1667 -0.9647 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I01 mock treatment 519172.0 -4120.0 -0.02 551077.0 48300.0 0.27 0.1769 0.6414 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I02 mock treatment 507123.0 -16200.0 -0.1 415356.0 -87400.0 -0.5 -0.4195 -0.8286 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I03 compound treatment 270018.0 -253000.0 -1.51 374015.0 -129000.0 -0.73 -1.5836 -0.945 3001079 BCB01_000161 CN1C(=O)C2C=CC(C(O)c3cccc(O)c3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I04 compound treatment 510547.0 -12700.0 -0.08 468089.0 -34700.0 -0.2 -0.1931 -0.9139 3093392 BCB01_000162 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I05 compound treatment 551088.0 27800.0 0.17 530411.0 27700.0 0.16 0.2282 0.9997 3093393 BCB01_000163 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I06 compound treatment 482470.0 -40800.0 -0.24 363831.0 -139000.0 -0.79 -0.7305 -0.8837 3001081 BCB01_000164 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I07 compound treatment 549409.0 26100.0 0.16 551348.0 48600.0 0.28 0.3053 0.9629 3093394 BCB01_000165 CN1C(=O)C2C=CC(C(O)c3cn(C(=O)C)c4ccccc34)N(Nc5ccccc5)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I08 compound treatment 73506.0 -450000.0 -2.68 55179.0 -448000.0 -2.55 -3.6926 -0.9997 3093395 BCB01_000166 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I09 compound treatment 490389.0 -32900.0 -0.2 522491.0 19700.0 0.11 -0.0591 -0.262 3001082 BCB01_000167 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I10 compound treatment 528171.0 4870.0 0.03 523977.0 21200.0 0.12 0.1058 0.8528 3093464 BCB01_000168 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I11 compound treatment 155621.0 -368000.0 -2.19 228460.0 -274000.0 -1.56 -2.6503 -0.9862 3001083 BCB01_000169 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I12 compound treatment 259191.0 -264000.0 -1.57 257247.0 -246000.0 -1.4 -2.0987 -0.9983 3093465 BCB01_000170 CN1C(=O)C2C=CC(C(O)c3cccn3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I13 compound treatment 489443.0 -33900.0 -0.2 502479.0 -278.0 0.0 -0.1436 -0.7126 3093466 BCB01_000171 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccc(C)o4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I14 compound treatment 345825.0 -177000.0 -1.06 429843.0 -72900.0 -0.41 -1.04 -0.9166 3001084 BCB01_000172 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I15 compound treatment 101065.0 -422000.0 -2.51 536082.0 33300.0 0.19 -1.6429 -0.6519 3093467 BCB01_000173 CN1C(=O)C2C=CC(C(O)c3cccs3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I16 compound treatment 510273.0 -13000.0 -0.08 441092.0 -61700.0 -0.35 -0.3028 -0.843 3093468 BCB01_000174 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I17 compound treatment 533008.0 9710.0 0.06 125200.0 -378000.0 -2.15 -1.4773 -0.6878 3001085 BCB01_000175 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I18 compound treatment 467255.0 -56000.0 -0.33 132245.0 -371000.0 -2.11 -1.7257 -0.809 3093469 BCB01_000176 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I19 compound treatment 256887.0 -266000.0 -1.59 155684.0 -347000.0 -1.97 -2.5168 -0.9941 3001086 BCB01_000177 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccccc5)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I20 compound treatment 567888.0 44600.0 0.27 460330.0 -42400.0 -0.24 0.017 0.0475 3093470 BCB01_000178 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I21 compound treatment 499691.0 -23600.0 -0.14 521069.0 18300.0 0.1 -0.0257 -0.147 3001087 BCB01_000179 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I22 compound treatment 375240.0 -148000.0 -0.88 314900.0 -188000.0 -1.07 -1.3785 -0.9954 3093471 BCB01_000180 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I23 mock treatment 562781.0 39500.0 0.23 468972.0 -33800.0 -0.19 0.0303 0.0998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 I24 mock treatment 556096.0 32800.0 0.2 570311.0 67600.0 0.38 0.4097 0.9507 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J01 mock treatment 518914.0 -4380.0 -0.03 585545.0 82800.0 0.47 0.3145 0.6669 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J02 mock treatment 487357.0 -35900.0 -0.21 478925.0 -23800.0 -0.14 -0.2471 -0.9758 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J03 compound treatment 306325.0 -217000.0 -1.29 515757.0 13000.0 0.07 -0.8608 -0.6655 3093472 BCB01_000181 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J04 compound treatment 465962.0 -57300.0 -0.34 491669.0 -11100.0 -0.06 -0.2859 -0.8238 3001088 BCB01_000182 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J05 compound treatment 245580.0 -278000.0 -1.65 537864.0 35100.0 0.2 -1.0275 -0.6172 3093473 BCB01_000183 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J06 compound treatment 446110.0 -77200.0 -0.46 460760.0 -42000.0 -0.24 -0.4937 -0.9536 3093474 BCB01_000184 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J07 compound treatment 473434.0 -49900.0 -0.3 496074.0 -6680.0 -0.04 -0.2367 -0.7912 3001089 BCB01_000185 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J08 compound treatment 525782.0 2490.0 0.01 480865.0 -21900.0 -0.12 -0.0776 -0.6187 3001153 BCB01_000186 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J09 compound treatment 51797.0 -471000.0 -2.81 101315.0 -401000.0 -2.28 -3.5985 -0.9948 3001154 BCB01_000187 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J10 compound treatment 516957.0 -6340.0 -0.04 514776.0 12000.0 0.07 0.0217 0.2773 3001156 BCB01_000188 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J11 compound treatment 471378.0 -51900.0 -0.31 566411.0 63700.0 0.36 0.0375 0.0787 3001157 BCB01_000189 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J12 compound treatment 518113.0 -5180.0 -0.03 496853.0 -5900.0 -0.03 -0.0456 -0.9991 3093475 BCB01_000190 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J13 compound treatment 428760.0 -94500.0 -0.56 536555.0 33800.0 0.19 -0.2619 -0.4406 3093476 BCB01_000191 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J14 compound treatment 565305.0 42000.0 0.25 485169.0 -17600.0 -0.1 0.1061 0.3939 3001159 BCB01_000192 CCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J15 compound treatment 486903.0 -36400.0 -0.22 494704.0 -8050.0 -0.05 -0.1855 -0.8381 3093477 BCB01_000193 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J16 compound treatment 48641.0 -475000.0 -2.82 51650.0 -451000.0 -2.57 -3.8115 -0.9988 3001160 BCB01_000194 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J17 compound treatment 522363.0 -933.0 -0.01 421468.0 -81300.0 -0.46 -0.3308 -0.7156 3093478 BCB01_000195 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J18 compound treatment 486663.0 -36600.0 -0.22 437561.0 -65200.0 -0.37 -0.4163 -0.968 3093479 BCB01_000196 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J19 compound treatment 479572.0 -43700.0 -0.26 455965.0 -46800.0 -0.27 -0.3722 -0.9999 3001161 BCB01_000197 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J20 compound treatment 510341.0 -13000.0 -0.08 472142.0 -30600.0 -0.17 -0.1776 -0.9329 3093480 BCB01_000198 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J21 compound treatment 576079.0 52800.0 0.31 473582.0 -29200.0 -0.17 0.1048 0.295 3093481 BCB01_000199 CCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J22 compound treatment 461314.0 -62000.0 -0.37 453446.0 -49300.0 -0.28 -0.4591 -0.9908 3001163 BCB01_000200 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J23 mock treatment 522492.0 -804.0 0.0 489630.0 -13100.0 -0.07 -0.0562 -0.7509 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 J24 mock treatment 515040.0 -8260.0 -0.05 427507.0 -75300.0 -0.43 -0.3373 -0.7832 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K01 mock treatment 556842.0 33500.0 0.2 550579.0 47800.0 0.27 0.3335 0.9884 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K02 mock treatment 458058.0 -65200.0 -0.39 501762.0 -995.0 -0.01 -0.2785 -0.7173 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K03 compound treatment 547130.0 23800.0 0.14 533683.0 30900.0 0.18 0.2247 0.9943 3093482 BCB01_000201 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K04 compound treatment 574151.0 50900.0 0.3 472230.0 -30500.0 -0.17 0.0913 0.2615 3001164 BCB01_000202 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K05 compound treatment 188816.0 -334000.0 -1.99 216710.0 -286000.0 -1.63 -2.5578 -0.995 3093483 BCB01_000203 CN1C(=O)C2C=CC(C(O)/C=C(\C)/CCC=C(C)C)N(Nc3ccccc3)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K06 compound treatment 513911.0 -9390.0 -0.06 508041.0 5280.0 0.03 -0.0182 -0.2877 3093484 BCB01_000204 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K07 compound treatment 525539.0 2240.0 0.01 558753.0 56000.0 0.32 0.2346 0.7361 3000112 BCB01_000205 CN1C(=O)C2C=CC(C(O)C(C)(C)C)N(Nc3ccccc3)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K08 compound treatment 598596.0 75300.0 0.45 551541.0 48800.0 0.28 0.513 0.9734 3000114 BCB01_000206 COc1ccc(cc1)C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K09 compound treatment 543788.0 20500.0 0.12 592366.0 89600.0 0.51 0.4466 0.8523 3000115 BCB01_000207 CCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K10 compound treatment 534712.0 11400.0 0.07 550787.0 48000.0 0.27 0.2412 0.8569 3000116 BCB01_000208 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K11 compound treatment 554957.0 31700.0 0.19 518248.0 15500.0 0.09 0.1955 0.94 3000118 BCB01_000209 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K12 compound treatment 412005.0 -111000.0 -0.66 427876.0 -74900.0 -0.43 -0.7695 -0.9772 3093485 BCB01_000210 CCCCC(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K13 compound treatment 570978.0 47700.0 0.28 533256.0 30500.0 0.17 0.3233 0.9721 3093645 BCB01_000211 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K14 compound treatment 528682.0 5390.0 0.03 507841.0 5080.0 0.03 0.0431 0.9987 3000120 BCB01_000212 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K15 compound treatment 568655.0 45400.0 0.27 518506.0 15700.0 0.09 0.2542 0.8938 3093555 BCB01_000213 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K16 compound treatment 553190.0 29900.0 0.18 508654.0 5900.0 0.03 0.1495 0.8258 3093556 BCB01_000214 COc1ccc(C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K17 compound treatment 537613.0 14300.0 0.09 560833.0 58100.0 0.33 0.2938 0.8613 3000122 BCB01_000215 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K18 compound treatment 475037.0 -48300.0 -0.29 559770.0 57000.0 0.32 0.0262 0.0604 3093557 BCB01_000216 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K19 compound treatment 512991.0 -10300.0 -0.06 518386.0 15600.0 0.09 0.0195 0.1804 3000123 BCB01_000217 OC(C#Cc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K20 compound treatment 480547.0 -42700.0 -0.25 394198.0 -109000.0 -0.62 -0.6164 -0.9232 3093558 BCB01_000218 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(C2C1=O)N(c5ccccc5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K21 compound treatment 477614.0 -45700.0 -0.27 389989.0 -113000.0 -0.64 -0.6457 -0.927 3093559 BCB01_000219 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K22 compound treatment 534368.0 11100.0 0.07 250611.0 -252000.0 -1.43 -0.9673 -0.6739 3000124 BCB01_000220 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K23 mock treatment 511181.0 -12100.0 -0.07 484216.0 -18500.0 -0.11 -0.1255 -0.9828 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 K24 mock treatment 471134.0 -52200.0 -0.31 533250.0 30500.0 0.17 -0.0969 -0.2725 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L01 mock treatment 632039.0 109000.0 0.65 527369.0 24600.0 0.14 0.5566 0.8406 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L02 mock treatment 558107.0 34800.0 0.21 486732.0 -16000.0 -0.09 0.0821 0.3625 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L03 compound treatment 63141.0 -460000.0 -2.74 55753.0 -447000.0 -2.54 -3.7339 -0.9993 3093560 BCB01_000221 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L04 compound treatment 502983.0 -20300.0 -0.12 513561.0 10800.0 0.06 -0.042 -0.31 3093561 BCB01_000222 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L05 compound treatment 457637.0 -65700.0 -0.39 458884.0 -43900.0 -0.25 -0.4527 -0.9765 3000127 BCB01_000223 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L06 compound treatment 470207.0 -53100.0 -0.32 466508.0 -36200.0 -0.21 -0.3692 -0.9786 3093562 BCB01_000224 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L07 compound treatment 577230.0 53900.0 0.32 544455.0 41700.0 0.24 0.3946 0.9889 3093563 BCB01_000225 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L08 compound treatment 537208.0 13900.0 0.08 572622.0 69900.0 0.4 0.3395 0.8365 3000128 BCB01_000226 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L09 compound treatment 565511.0 42200.0 0.25 340434.0 -162000.0 -0.92 -0.4751 -0.4966 3093564 BCB01_000227 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L10 compound treatment 551572.0 28300.0 0.17 550823.0 48100.0 0.27 0.3123 0.9729 3000129 BCB01_000228 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4c(F)cccc4Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L11 compound treatment 579119.0 55800.0 0.33 527082.0 24300.0 0.14 0.3327 0.9246 3093565 BCB01_000229 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L12 compound treatment 530600.0 7300.0 0.04 476537.0 -26200.0 -0.15 -0.0747 -0.481 3093566 BCB01_000230 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L13 compound treatment 528229.0 4930.0 0.03 128191.0 -375000.0 -2.13 -1.4854 -0.6973 3000131 BCB01_000231 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L14 compound treatment 262448.0 -261000.0 -1.55 280517.0 -222000.0 -1.26 -1.9914 -0.9948 3093567 BCB01_000232 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L15 compound treatment 446481.0 -76800.0 -0.46 223758.0 -279000.0 -1.59 -1.4452 -0.8752 3093568 BCB01_000233 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L16 compound treatment 554777.0 31500.0 0.19 524507.0 21700.0 0.12 0.2199 0.9797 3000133 BCB01_000234 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c(C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L17 compound treatment 501371.0 -21900.0 -0.13 502622.0 -135.0 0.0 -0.0928 -0.7113 3093569 BCB01_000235 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L18 compound treatment 500157.0 -23100.0 -0.14 509422.0 6660.0 0.04 -0.0706 -0.4941 3000205 BCB01_000236 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L19 compound treatment 492289.0 -31000.0 -0.18 423720.0 -79000.0 -0.45 -0.4483 -0.9227 3000206 BCB01_000237 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L20 compound treatment 516767.0 -6530.0 -0.04 474582.0 -28200.0 -0.16 -0.1408 -0.8538 3000207 BCB01_000238 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L21 compound treatment 538195.0 14900.0 0.09 459137.0 -43600.0 -0.25 -0.1127 -0.4278 3000208 BCB01_000239 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L22 compound treatment 546182.0 22900.0 0.14 561257.0 58500.0 0.33 0.3315 0.9223 3093570 BCB01_000240 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L23 mock treatment 475523.0 -47800.0 -0.28 535949.0 33200.0 0.19 -0.0676 -0.198 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 L24 mock treatment 519036.0 -4260.0 -0.03 458288.0 -44500.0 -0.25 -0.1967 -0.7741 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M01 mock treatment 531713.0 8420.0 0.05 578804.0 76000.0 0.43 0.3412 0.7838 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M02 mock treatment 233123.0 -290000.0 -1.73 515256.0 12500.0 0.07 -1.1709 -0.6774 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M03 compound treatment 513614.0 -9680.0 -0.06 574772.0 72000.0 0.41 0.2488 0.6017 3000209 BCB01_000241 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M04 compound treatment 576382.0 53100.0 0.32 479528.0 -23200.0 -0.13 0.13 0.3796 3093571 BCB01_000242 C/C=C/C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M05 compound treatment 526268.0 2970.0 0.02 555675.0 52900.0 0.3 0.2253 0.7474 3093572 BCB01_000243 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M06 compound treatment 560071.0 36800.0 0.22 464455.0 -38300.0 -0.22 7.0E-4 0.0024 3000211 BCB01_000244 CC(C)C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M07 compound treatment 450952.0 -72300.0 -0.43 429787.0 -73000.0 -0.41 -0.5979 -0.9998 3093573 BCB01_000245 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M08 compound treatment 546990.0 23700.0 0.14 611046.0 108000.0 0.62 0.5352 0.8471 3093574 BCB01_000246 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M09 compound treatment 560969.0 37700.0 0.22 602960.0 100000.0 0.57 0.5615 0.9169 3000213 BCB01_000247 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M10 compound treatment 492846.0 -30500.0 -0.18 551146.0 48400.0 0.28 0.0664 0.2016 3093575 BCB01_000248 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M11 compound treatment 474722.0 -48600.0 -0.29 510402.0 7640.0 0.04 -0.1737 -0.5941 3000215 BCB01_000249 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M12 compound treatment 580132.0 56800.0 0.34 556473.0 53700.0 0.31 0.4552 0.9987 3093576 BCB01_000250 CC(C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M13 compound treatment 532887.0 9590.0 0.06 555137.0 52400.0 0.3 0.251 0.8275 3093646 BCB01_000251 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M14 compound treatment 514014.0 -9280.0 -0.06 622407.0 120000.0 0.68 0.4421 0.6476 3000219 BCB01_000252 CN1C(=O)C2C=CC(C(O)c3cccs3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M15 compound treatment 553919.0 30600.0 0.18 554426.0 51700.0 0.29 0.3366 0.9736 3093647 BCB01_000253 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M16 compound treatment 558030.0 34700.0 0.21 307332.0 -195000.0 -1.11 -0.6397 -0.5659 3000221 BCB01_000254 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M17 compound treatment 459380.0 -63900.0 -0.38 597295.0 94500.0 0.54 0.1112 0.1688 3093648 BCB01_000255 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M18 compound treatment 511735.0 -11600.0 -0.07 520368.0 17600.0 0.1 0.0222 0.1824 3093649 BCB01_000256 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M19 compound treatment 212827.0 -310000.0 -1.85 72078.0 -431000.0 -2.45 -3.0384 -0.9903 3000223 BCB01_000257 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M20 compound treatment 54422.0 -469000.0 -2.79 50675.0 -452000.0 -2.57 -3.791 -0.9992 3093650 BCB01_000258 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M21 compound treatment 266808.0 -256000.0 -1.53 214067.0 -289000.0 -1.64 -2.2402 -0.9993 3093651 BCB01_000259 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M22 compound treatment 517657.0 -5640.0 -0.03 467007.0 -35800.0 -0.2 -0.1675 -0.8128 3000225 BCB01_000260 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M23 mock treatment 519261.0 -4040.0 -0.02 503546.0 789.0 0.0 -0.0138 -0.5653 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 M24 mock treatment 533178.0 9880.0 0.06 524209.0 21500.0 0.12 0.1278 0.944 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N01 mock treatment 537365.0 14100.0 0.08 479979.0 -22800.0 -0.13 -0.0324 -0.21 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N02 mock treatment 534191.0 10900.0 0.06 542748.0 40000.0 0.23 0.2067 0.8739 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N03 compound treatment 526893.0 3600.0 0.02 499413.0 -3340.0 -0.02 0.0017 0.059 3093652 BCB01_000261 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N04 compound treatment 515909.0 -7390.0 -0.04 510983.0 8230.0 0.05 0.002 0.031 3093653 BCB01_000262 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N05 compound treatment 494594.0 -28700.0 -0.17 556826.0 54100.0 0.31 0.0966 0.2747 3000227 BCB01_000263 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N06 compound treatment 478557.0 -44700.0 -0.27 492835.0 -9920.0 -0.06 -0.2282 -0.8383 3093654 BCB01_000264 C/C=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N07 compound treatment 516310.0 -6990.0 -0.04 579085.0 76300.0 0.43 0.2775 0.6365 3093655 BCB01_000265 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N08 compound treatment 512504.0 -10800.0 -0.06 551954.0 49200.0 0.28 0.1524 0.531 3000229 BCB01_000266 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N09 compound treatment 544585.0 21300.0 0.13 588876.0 86100.0 0.49 0.4359 0.8617 3093656 BCB01_000267 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N10 compound treatment 545962.0 22700.0 0.13 541854.0 39100.0 0.22 0.2526 0.9713 3000231 BCB01_000268 CC(C)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N11 compound treatment 496944.0 -26400.0 -0.16 514718.0 12000.0 0.07 -0.0628 -0.3674 3093657 BCB01_000269 CC(C)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N12 compound treatment 488651.0 -34600.0 -0.21 553472.0 50700.0 0.29 0.0581 0.164 3000297 BCB01_000270 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N13 compound treatment 575462.0 52200.0 0.31 422316.0 -80400.0 -0.46 -0.1039 -0.188 3000298 BCB01_000271 OB(O)c1ccc(cc1)C(O)C2C=CC3CN(C(=O)C3N2Nc4ccc(C#N)cc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N14 compound treatment 521031.0 -2270.0 -0.01 511040.0 8280.0 0.05 0.0238 0.4852 3000299 BCB01_000272 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N15 compound treatment 455910.0 -67400.0 -0.4 494272.0 -8490.0 -0.05 -0.3177 -0.7865 3093658 BCB01_000273 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N16 compound treatment 465863.0 -57400.0 -0.34 535432.0 32700.0 0.19 -0.1103 -0.2835 3093659 BCB01_000274 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N17 compound treatment 565438.0 42100.0 0.25 519580.0 16800.0 0.1 0.245 0.9127 3000301 BCB01_000275 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N18 compound treatment 528515.0 5220.0 0.03 429010.0 -73700.0 -0.42 -0.2746 -0.653 3093660 BCB01_000276 CC(C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N19 compound treatment 495265.0 -28000.0 -0.17 486742.0 -16000.0 -0.09 -0.1824 -0.9595 3093661 BCB01_000277 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N20 compound treatment 456752.0 -66500.0 -0.4 489638.0 -13100.0 -0.07 -0.3328 -0.8258 3000302 BCB01_000278 CC(CC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C)o4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N21 compound treatment 515544.0 -7750.0 -0.05 512949.0 10200.0 0.06 0.0084 0.1128 3093662 BCB01_000279 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N22 compound treatment 554334.0 31000.0 0.18 499959.0 -2800.0 -0.02 0.1194 0.6438 3093663 BCB01_000280 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N23 mock treatment 462243.0 -61100.0 -0.36 551205.0 48400.0 0.28 -0.0621 -0.1362 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 N24 mock treatment 561988.0 38700.0 0.23 540868.0 38100.0 0.22 0.3161 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O01 mock treatment 550835.0 27500.0 0.16 542481.0 39700.0 0.23 0.2756 0.9876 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O02 mock treatment 464642.0 -58700.0 -0.35 522510.0 19800.0 0.11 -0.1674 -0.4565 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O03 compound treatment 356396.0 -167000.0 -0.99 559514.0 56800.0 0.32 -0.4741 -0.454 3000303 BCB01_000281 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O04 compound treatment 468300.0 -55000.0 -0.33 470680.0 -32100.0 -0.18 -0.3604 -0.9619 3093664 BCB01_000282 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O05 compound treatment 504266.0 -19000.0 -0.11 438753.0 -64000.0 -0.36 -0.3375 -0.8853 3093665 BCB01_000283 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O06 compound treatment 521329.0 -1970.0 -0.01 452455.0 -50300.0 -0.29 -0.2106 -0.7354 3000304 BCB01_000284 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O07 compound treatment 545417.0 22100.0 0.13 326753.0 -176000.0 -1.0 -0.6146 -0.6089 3093666 BCB01_000285 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O08 compound treatment 389100.0 -134000.0 -0.8 368739.0 -134000.0 -0.76 -1.1036 -0.9997 3093667 BCB01_000286 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)C(=O)C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O09 compound treatment 633995.0 111000.0 0.66 521508.0 18800.0 0.11 0.5413 0.811 3000307 BCB01_000287 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O10 compound treatment 513001.0 -10300.0 -0.06 418718.0 -84000.0 -0.48 -0.3813 -0.7913 3093736 BCB01_000288 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O11 compound treatment 654500.0 131000.0 0.78 596330.0 93600.0 0.53 0.9284 0.9825 3000308 BCB01_000289 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O12 compound treatment 550089.0 26800.0 0.16 436167.0 -66600.0 -0.38 -0.155 -0.3773 3093737 BCB01_000290 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O13 compound treatment 531517.0 8220.0 0.05 503730.0 973.0 0.01 0.0385 0.7821 3093738 BCB01_000291 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O14 compound treatment 462011.0 -61300.0 -0.36 416892.0 -85900.0 -0.49 -0.6032 -0.9897 3000310 BCB01_000292 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O15 compound treatment 466356.0 -56900.0 -0.34 570314.0 67600.0 0.38 0.032 0.0625 3093739 BCB01_000293 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O16 compound treatment 340560.0 -183000.0 -1.09 415283.0 -87500.0 -0.5 -1.1208 -0.9372 3000311 BCB01_000294 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O17 compound treatment 415456.0 -108000.0 -0.64 460533.0 -42200.0 -0.24 -0.6236 -0.9101 3093740 BCB01_000295 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O18 compound treatment 438930.0 -84400.0 -0.5 486852.0 -15900.0 -0.09 -0.419 -0.8213 3093741 BCB01_000296 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O19 compound treatment 538424.0 15100.0 0.09 540096.0 37300.0 0.21 0.2138 0.927 3000313 BCB01_000297 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O20 compound treatment 446379.0 -76900.0 -0.46 450359.0 -52400.0 -0.3 -0.5344 -0.9784 3093742 BCB01_000298 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O21 compound treatment 548855.0 25600.0 0.15 444556.0 -58200.0 -0.33 -0.1265 -0.3472 3000315 BCB01_000299 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O22 compound treatment 402224.0 -121000.0 -0.72 446236.0 -56500.0 -0.32 -0.7368 -0.9338 3093743 BCB01_000300 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)C(C)C)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O23 mock treatment 479356.0 -43900.0 -0.26 476738.0 -26000.0 -0.15 -0.2895 -0.9636 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 O24 mock treatment 520834.0 -2460.0 -0.01 534999.0 32200.0 0.18 0.1193 0.6485 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P01 mock treatment 582670.0 59400.0 0.35 561306.0 58500.0 0.33 0.4853 0.9996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P02 mock treatment 577832.0 54500.0 0.32 527744.0 25000.0 0.14 0.33 0.9313 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P03 compound treatment 602155.0 78900.0 0.47 519859.0 17100.0 0.1 0.4006 0.8359 3000135 BCB01_000301 CC(C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P04 compound treatment 523912.0 616.0 0.0 459645.0 -43100.0 -0.25 -0.1708 -0.6965 3000137 BCB01_000302 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P05 compound treatment 70678.0 -453000.0 -2.69 55399.0 -447000.0 -2.54 -3.7036 -0.9996 3000138 BCB01_000303 CC(CC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P06 compound treatment 541729.0 18400.0 0.11 591700.0 88900.0 0.51 0.4352 0.8409 3000139 BCB01_000304 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C#N)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P07 compound treatment 514409.0 -8890.0 -0.05 488076.0 -14700.0 -0.08 -0.0964 -0.9757 3093744 BCB01_000305 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P08 compound treatment 466652.0 -56600.0 -0.34 566453.0 63700.0 0.36 0.0178 0.0359 3000141 BCB01_000306 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P09 compound treatment 636339.0 113000.0 0.67 231505.0 -271000.0 -1.54 -0.615 -0.3655 3093745 BCB01_000307 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P10 compound treatment 485676.0 -37600.0 -0.22 530125.0 27400.0 0.16 -0.0483 -0.177 3093746 BCB01_000308 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P11 compound treatment 501299.0 -22000.0 -0.13 574851.0 72100.0 0.41 0.1973 0.4585 3000143 BCB01_000309 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P12 compound treatment 627107.0 104000.0 0.62 610526.0 108000.0 0.61 0.8702 1.0 3093747 BCB01_000310 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P13 compound treatment 309325.0 -214000.0 -1.27 315176.0 -188000.0 -1.07 -1.6547 -0.9961 3093748 BCB01_000311 CC(=CCC/C=C(\C)/C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P14 compound treatment 624694.0 101000.0 0.6 550142.0 47400.0 0.27 0.6173 0.934 3000145 BCB01_000312 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P15 compound treatment 67563.0 -456000.0 -2.71 98074.0 -405000.0 -2.3 -3.5451 -0.9967 3093749 BCB01_000313 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P16 compound treatment 522283.0 -1010.0 -0.01 611789.0 109000.0 0.62 0.4342 0.7002 3093750 BCB01_000314 OCC(O)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P17 compound treatment 47521.0 -476000.0 -2.83 48506.0 -454000.0 -2.58 -3.8288 -0.999 3000147 BCB01_000315 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(I)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P18 compound treatment 525214.0 1920.0 0.01 550549.0 47800.0 0.27 0.2002 0.7362 3093751 BCB01_000316 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P19 compound treatment 416422.0 -107000.0 -0.64 552142.0 49400.0 0.28 -0.2512 -0.3612 3093752 BCB01_000317 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P20 compound treatment 452110.0 -71200.0 -0.42 577667.0 74900.0 0.43 0.0017 0.0027 3000149 BCB01_000318 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P21 compound treatment 611148.0 87900.0 0.52 559109.0 56400.0 0.32 0.5963 0.9724 3093752 BCB01_000319 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P22 compound treatment 618667.0 95400.0 0.57 551997.0 49200.0 0.28 0.5993 0.947 3093753 BCB01_000320 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P23 mock treatment 522396.0 -900.0 -0.01 511212.0 8450.0 0.05 0.0302 0.6244 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2000 P24 mock treatment 592426.0 69100.0 0.41 563977.0 61200.0 0.35 0.5371 0.9965 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A01 compound treatment 106457.0 -343000.0 -2.04 329990.0 -126000.0 -0.72 -1.9497 -0.9017 3000745 BCB02_000001 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A02 compound treatment 211736.0 -237000.0 -1.41 315108.0 -141000.0 -0.8 -1.5665 -0.964 3000746 BCB02_000002 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A03 compound treatment 313035.0 -136000.0 -0.81 486145.0 30000.0 0.17 -0.4525 -0.5465 3000747 BCB02_000003 OC(C1CCCCC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A04 compound treatment 393878.0 -55300.0 -0.33 392591.0 -63600.0 -0.36 -0.4885 -0.9989 3000748 BCB02_000004 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A05 compound treatment 469317.0 20100.0 0.12 525744.0 69600.0 0.4 0.3644 0.8817 3000749 BCB02_000005 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A06 compound treatment 483116.0 33900.0 0.2 478549.0 22400.0 0.13 0.2327 0.9751 3000750 BCB02_000006 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A07 compound treatment 426622.0 -22600.0 -0.13 524287.0 68100.0 0.39 0.1789 0.4365 3093754 BCB02_000007 CCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A08 compound treatment 500646.0 51500.0 0.31 458414.0 2230.0 0.01 0.2255 0.7357 2065163 BCB02_000008 CCOC(=O)/C=C/c1ccccc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A09 compound treatment 316962.0 -132000.0 -0.79 466620.0 10400.0 0.06 -0.5145 -0.6519 3093755 BCB02_000009 CCCCCCCCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A10 compound treatment 340573.0 -109000.0 -0.65 412408.0 -43800.0 -0.25 -0.6331 -0.914 3000752 BCB02_000010 CCOC(=O)/C=C/c1cc(F)ccc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A11 compound treatment 405608.0 -43600.0 -0.26 480016.0 23800.0 0.14 -0.0875 -0.2992 3093756 BCB02_000011 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A12 compound treatment 423114.0 -26100.0 -0.16 511393.0 55200.0 0.31 0.1123 0.3207 3000753 BCB02_000012 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A13 compound treatment 449151.0 -31.1 0.0 556995.0 101000.0 0.57 0.4052 0.7069 3093757 BCB02_000013 COc1ccc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A14 compound treatment 441918.0 -7260.0 -0.04 565220.0 109000.0 0.62 0.4079 0.6562 3000754 BCB02_000014 CCOC(=O)/C=C/c1cccc(OC)c1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A15 compound treatment 437035.0 -12100.0 -0.07 437760.0 -18400.0 -0.1 -0.1252 -0.9836 3093824 BCB02_000015 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A16 compound treatment 351621.0 -97600.0 -0.58 425008.0 -31200.0 -0.18 -0.5359 -0.8828 3000755 BCB02_000016 CCOC(=O)/C=C/c1cccc(C)c1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A17 mock treatment 413073.0 -36100.0 -0.21 234251.0 -222000.0 -1.26 -1.0444 -0.8158 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A18 mock treatment 414380.0 -34800.0 -0.21 648742.0 193000.0 1.1 0.6278 0.5634 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A19 mock treatment 481785.0 32600.0 0.19 504772.0 48600.0 0.28 0.3326 0.985 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A20 mock treatment 396761.0 -52400.0 -0.31 280016.0 -176000.0 -1.0 -0.929 -0.8854 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A21 mock treatment 417359.0 -31800.0 -0.19 465634.0 9450.0 0.05 -0.0959 -0.4873 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A22 mock treatment 430946.0 -18200.0 -0.11 484878.0 28700.0 0.16 0.0386 0.1971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A23 mock treatment 490295.0 41100.0 0.24 585702.0 130000.0 0.74 0.6938 0.894 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 A24 mock treatment 465266.0 16100.0 0.1 508878.0 52700.0 0.3 0.2796 0.8887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B01 compound treatment 420699.0 -28500.0 -0.17 534596.0 78400.0 0.45 0.1954 0.4097 3093825 BCB02_000017 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B02 compound treatment 439242.0 -9940.0 -0.06 512003.0 55800.0 0.32 0.1826 0.5656 3000756 BCB02_000018 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B03 compound treatment 424327.0 -24900.0 -0.15 490822.0 34600.0 0.2 0.0347 0.1408 3093826 BCB02_000019 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B04 compound treatment 412206.0 -37000.0 -0.22 490632.0 34400.0 0.2 -0.0171 -0.058 3000757 BCB02_000020 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B05 compound treatment 412363.0 -36800.0 -0.22 347192.0 -109000.0 -0.62 -0.5932 -0.9024 3093827 BCB02_000021 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(s5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B06 compound treatment 379332.0 -69900.0 -0.42 359797.0 -96400.0 -0.55 -0.6815 -0.9907 3093828 BCB02_000022 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B07 compound treatment 414232.0 -35000.0 -0.21 482847.0 26700.0 0.15 -0.0399 -0.1549 3000758 BCB02_000023 CC(C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B08 compound treatment 399467.0 -49700.0 -0.3 243145.0 -213000.0 -1.21 -1.0659 -0.8547 3093829 BCB02_000024 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B09 compound treatment 396589.0 -52600.0 -0.31 404943.0 -51200.0 -0.29 -0.4274 -0.9994 3000759 BCB02_000025 CC(CC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(C)o5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B10 compound treatment 427168.0 -22000.0 -0.13 417226.0 -39000.0 -0.22 -0.2493 -0.9686 3093830 BCB02_000026 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B11 compound treatment 363893.0 -85300.0 -0.51 469897.0 13700.0 0.08 -0.3038 -0.5915 3093831 BCB02_000027 OC(Cc1ccccc1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B12 compound treatment 419779.0 -29400.0 -0.17 424617.0 -31600.0 -0.18 -0.2507 -0.9999 3000760 BCB02_000028 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B13 compound treatment 400275.0 -48900.0 -0.29 468232.0 12000.0 0.07 -0.1574 -0.5263 3093832 BCB02_000029 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B14 compound treatment 353640.0 -95500.0 -0.57 529505.0 73300.0 0.42 -0.1072 -0.1521 3093833 BCB02_000030 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B15 compound treatment 354183.0 -95000.0 -0.57 355008.0 -101000.0 -0.58 -0.8066 -1.0 3000761 BCB02_000031 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B16 compound treatment 408995.0 -40200.0 -0.24 388832.0 -67400.0 -0.38 -0.44 -0.9743 3093834 BCB02_000032 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B17 mock treatment 331069.0 -118000.0 -0.7 447417.0 -8770.0 -0.05 -0.5323 -0.7554 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B18 mock treatment 418708.0 -30500.0 -0.18 425082.0 -31100.0 -0.18 -0.2533 -0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B19 mock treatment 375980.0 -73200.0 -0.44 387773.0 -68400.0 -0.39 -0.5832 -0.9984 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B20 mock treatment 414933.0 -34200.0 -0.2 403060.0 -53100.0 -0.3 -0.3578 -0.9817 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B21 mock treatment 361708.0 -87500.0 -0.52 417264.0 -38900.0 -0.22 -0.5246 -0.9274 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B22 mock treatment 466680.0 17500.0 0.1 421957.0 -34200.0 -0.19 -0.064 -0.2899 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B23 mock treatment 394312.0 -54900.0 -0.33 433284.0 -22900.0 -0.13 -0.323 -0.9187 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 B24 mock treatment 457553.0 8370.0 0.05 579453.0 123000.0 0.7 0.5309 0.7555 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C01 compound treatment 214675.0 -235000.0 -1.4 494305.0 38100.0 0.22 -0.8336 -0.5902 3093835 BCB02_000033 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C02 compound treatment 42143.0 -407000.0 -2.42 69818.0 -386000.0 -2.2 -3.2666 -0.9988 3000762 BCB02_000034 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C03 compound treatment 247155.0 -202000.0 -1.2 483110.0 26900.0 0.15 -0.7419 -0.6121 3000763 BCB02_000035 Cc1ccccc1C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C04 compound treatment 338198.0 -111000.0 -0.66 236040.0 -220000.0 -1.25 -1.3523 -0.9554 3093836 BCB02_000036 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C05 compound treatment 431739.0 -17400.0 -0.1 416717.0 -39500.0 -0.22 -0.2321 -0.9386 3093837 BCB02_000037 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C06 compound treatment 91372.0 -358000.0 -2.13 110357.0 -346000.0 -1.97 -2.8964 -0.9992 3000764 BCB02_000038 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C07 compound treatment 243058.0 -206000.0 -1.23 399700.0 -56500.0 -0.32 -1.0946 -0.8632 3093838 BCB02_000039 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C08 compound treatment 63485.0 -386000.0 -2.3 70182.0 -386000.0 -2.2 -3.1753 -0.9998 3000765 BCB02_000040 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C09 compound treatment 403885.0 -45300.0 -0.27 387350.0 -68800.0 -0.39 -0.4674 -0.9834 3093839 BCB02_000041 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C10 compound treatment 351610.0 -97600.0 -0.58 326595.0 -130000.0 -0.74 -0.9317 -0.993 3000766 BCB02_000042 O=c1oc2ccccc2cc1C#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C11 compound treatment 393097.0 -56100.0 -0.33 420677.0 -35500.0 -0.2 -0.3788 -0.971 3093840 BCB02_000043 OC(C1CCC=CC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C12 compound treatment 447973.0 -1210.0 -0.01 414018.0 -42200.0 -0.24 -0.1746 -0.728 3000767 BCB02_000044 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C13 compound treatment 239930.0 -209000.0 -1.25 396732.0 -59500.0 -0.34 -1.1197 -0.8677 3093841 BCB02_000045 CC(=O)n1cc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C14 compound treatment 376514.0 -72700.0 -0.43 377087.0 -79100.0 -0.45 -0.6239 -0.9998 3000768 BCB02_000046 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C15 compound treatment 390932.0 -58300.0 -0.35 476081.0 19900.0 0.11 -0.1651 -0.4528 3093842 BCB02_000047 CCCCC(CC)C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C16 compound treatment 406878.0 -42300.0 -0.25 382999.0 -73200.0 -0.42 -0.4723 -0.971 3093843 BCB02_000048 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C17 mock treatment 404590.0 -44600.0 -0.27 228703.0 -227000.0 -1.29 -1.1024 -0.8348 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C18 mock treatment 394375.0 -54800.0 -0.33 400821.0 -55400.0 -0.31 -0.4533 -0.9998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C19 mock treatment 494249.0 45100.0 0.27 403656.0 -52500.0 -0.3 -0.0216 -0.0537 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C20 mock treatment 447896.0 -1290.0 -0.01 397945.0 -58200.0 -0.33 -0.2396 -0.7233 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C21 mock treatment 400111.0 -49100.0 -0.29 470787.0 14600.0 0.08 -0.1478 -0.4868 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C22 mock treatment 474600.0 25400.0 0.15 448240.0 -7950.0 -0.05 0.075 0.4752 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C23 mock treatment 465441.0 16300.0 0.1 416696.0 -39500.0 -0.22 -0.0904 -0.3696 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 C24 mock treatment 553609.0 104000.0 0.62 464340.0 8150.0 0.05 0.4722 0.7578 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D01 compound treatment 264120.0 -185000.0 -1.1 470850.0 14700.0 0.08 -0.7198 -0.6517 3000769 BCB02_000049 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D02 compound treatment 413806.0 -35400.0 -0.21 518464.0 62300.0 0.35 0.1016 0.2465 3093844 BCB02_000050 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D03 compound treatment 450218.0 1040.0 0.01 502224.0 46000.0 0.26 0.1895 0.7236 3093845 BCB02_000051 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D04 compound treatment 355032.0 -94200.0 -0.56 485417.0 29200.0 0.17 -0.2787 -0.4768 3000770 BCB02_000052 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D05 compound treatment 375639.0 -73500.0 -0.44 319341.0 -137000.0 -0.78 -0.8598 -0.963 3093846 BCB02_000053 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D06 compound treatment 301542.0 -148000.0 -0.88 327241.0 -129000.0 -0.73 -1.1398 -0.996 3000771 BCB02_000054 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D07 compound treatment 402041.0 -47100.0 -0.28 474051.0 17900.0 0.1 -0.1265 -0.4241 3092586 BCB02_000055 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D08 compound treatment 103537.0 -346000.0 -2.06 305388.0 -151000.0 -0.86 -2.061 -0.9247 3092495 BCB02_000056 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D09 compound treatment 427371.0 -21800.0 -0.13 541228.0 85000.0 0.48 0.2502 0.4996 3000772 BCB02_000057 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D10 compound treatment 346312.0 -103000.0 -0.61 409647.0 -46500.0 -0.26 -0.62 -0.9296 3092496 BCB02_000058 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D11 compound treatment 404113.0 -45100.0 -0.27 121838.0 -334000.0 -1.9 -1.5341 -0.7989 3092497 BCB02_000059 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D12 compound treatment 292395.0 -157000.0 -0.93 290702.0 -165000.0 -0.94 -1.3252 -1.0 3000773 BCB02_000060 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D13 compound treatment 398586.0 -50600.0 -0.3 407153.0 -49000.0 -0.28 -0.4101 -0.9993 3092498 BCB02_000061 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D14 compound treatment 317079.0 -132000.0 -0.79 361179.0 -95000.0 -0.54 -0.938 -0.9832 3000774 BCB02_000062 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D15 compound treatment 383941.0 -65200.0 -0.39 225179.0 -231000.0 -1.31 -1.2035 -0.8785 3092499 BCB02_000063 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D16 compound treatment 326401.0 -123000.0 -0.73 333074.0 -123000.0 -0.7 -1.0117 -0.9998 3000775 BCB02_000064 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D17 mock treatment 336653.0 -113000.0 -0.67 387051.0 -69100.0 -0.39 -0.7516 -0.9678 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D18 mock treatment 427083.0 -22100.0 -0.13 217941.0 -238000.0 -1.35 -1.051 -0.7721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D19 mock treatment 431687.0 -17500.0 -0.1 120825.0 -335000.0 -1.91 -1.4222 -0.7446 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D20 mock treatment 360783.0 -88400.0 -0.53 49735.0 -406000.0 -2.31 -2.0064 -0.8464 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D21 mock treatment 213792.0 -235000.0 -1.4 154618.0 -302000.0 -1.71 -2.2032 -0.995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D22 mock treatment 387217.0 -62000.0 -0.37 438384.0 -17800.0 -0.1 -0.3323 -0.8691 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D23 mock treatment 403543.0 -45600.0 -0.27 420031.0 -36200.0 -0.21 -0.3374 -0.9906 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 D24 mock treatment 444732.0 -4450.0 -0.03 201063.0 -255000.0 -1.45 -1.0446 -0.7199 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E01 compound treatment 478908.0 29700.0 0.18 565897.0 110000.0 0.62 0.5663 0.8732 3092500 BCB02_000065 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E02 compound treatment 415255.0 -33900.0 -0.2 466851.0 10700.0 0.06 -0.0999 -0.4738 3000776 BCB02_000066 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E03 compound treatment 445178.0 -4000.0 -0.02 453357.0 -2830.0 -0.02 -0.0282 -0.9817 3000847 BCB02_000067 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E04 compound treatment 409805.0 -39400.0 -0.23 442013.0 -14200.0 -0.08 -0.2227 -0.8986 3000848 BCB02_000068 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E05 compound treatment 388800.0 -60400.0 -0.36 395961.0 -60200.0 -0.34 -0.4963 -0.9997 3000849 BCB02_000069 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(Br)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E06 compound treatment 243475.0 -206000.0 -1.22 444781.0 -11400.0 -0.06 -0.9115 -0.7435 3000850 BCB02_000070 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E07 compound treatment 157834.0 -291000.0 -1.73 399695.0 -56500.0 -0.32 -1.4532 -0.8241 3000851 BCB02_000071 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E08 compound treatment 236630.0 -213000.0 -1.26 445161.0 -11000.0 -0.06 -0.9388 -0.7412 3092501 BCB02_000072 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E09 compound treatment 430365.0 -18800.0 -0.11 465125.0 8940.0 0.05 -0.0432 -0.3516 3000852 BCB02_000073 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E10 compound treatment 222232.0 -227000.0 -1.35 249322.0 -207000.0 -1.18 -1.7869 -0.9976 3092502 BCB02_000074 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E11 compound treatment 379668.0 -69500.0 -0.41 405774.0 -50400.0 -0.29 -0.4952 -0.9839 3092503 BCB02_000075 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E12 compound treatment 318702.0 -130000.0 -0.78 290405.0 -166000.0 -0.94 -1.2157 -0.9954 3000853 BCB02_000076 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E13 compound treatment 350043.0 -99100.0 -0.59 391731.0 -64500.0 -0.37 -0.6764 -0.9738 3092504 BCB02_000077 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E14 compound treatment 288025.0 -161000.0 -0.96 439730.0 -16500.0 -0.09 -0.7444 -0.7724 3000854 BCB02_000078 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E15 compound treatment 368164.0 -81000.0 -0.48 209696.0 -246000.0 -1.4 -1.3321 -0.8987 3092505 BCB02_000079 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E16 compound treatment 189635.0 -260000.0 -1.54 152182.0 -304000.0 -1.73 -2.3147 -0.9984 3000855 BCB02_000080 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E17 mock treatment 474747.0 25600.0 0.15 215346.0 -241000.0 -1.37 -0.8609 -0.6247 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E18 mock treatment 164139.0 -285000.0 -1.7 354818.0 -101000.0 -0.58 -1.6072 -0.897 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E19 mock treatment 418521.0 -30700.0 -0.18 509268.0 53100.0 0.3 0.0844 0.2393 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E20 mock treatment 163687.0 -285000.0 -1.7 370563.0 -85600.0 -0.49 -1.5457 -0.8745 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E21 mock treatment 165644.0 -284000.0 -1.69 212787.0 -243000.0 -1.38 -2.1719 -0.9952 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E22 mock treatment 270408.0 -179000.0 -1.06 306378.0 -150000.0 -0.85 -1.3547 -0.9939 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E23 mock treatment 167593.0 -282000.0 -1.68 453008.0 -3180.0 -0.02 -1.1978 -0.7147 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 E24 mock treatment 295370.0 -154000.0 -0.92 469587.0 13400.0 0.08 -0.5934 -0.646 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F01 compound treatment 495803.0 46600.0 0.28 381373.0 -74800.0 -0.43 -0.1046 -0.206 3092506 BCB02_000081 OC(COCc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F02 compound treatment 240435.0 -209000.0 -1.24 415419.0 -40800.0 -0.23 -1.0424 -0.8248 3092507 BCB02_000082 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F03 compound treatment 171094.0 -278000.0 -1.66 407190.0 -49000.0 -0.28 -1.3673 -0.8147 3000856 BCB02_000083 COc1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F04 compound treatment 79827.0 -369000.0 -2.2 150104.0 -306000.0 -1.74 -2.7851 -0.9933 3092508 BCB02_000084 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F05 compound treatment 429330.0 -19900.0 -0.12 496895.0 40700.0 0.23 0.0802 0.3084 3092509 BCB02_000085 CCCCC(O)C1C=CC2C(N1Nc3ccc(OC)cc3)C(=O)N(C4CCCCC4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F06 compound treatment 118525.0 -331000.0 -1.97 415712.0 -40500.0 -0.23 -1.5542 -0.7845 3000857 BCB02_000086 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F07 compound treatment 158557.0 -291000.0 -1.73 499412.0 43200.0 0.25 -1.0492 -0.6006 3092510 BCB02_000087 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F08 compound treatment 433807.0 -15400.0 -0.09 406139.0 -50000.0 -0.28 -0.2659 -0.8896 3000858 BCB02_000088 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F09 compound treatment 545160.0 96000.0 0.57 556408.0 100000.0 0.57 0.8069 1.0 3092511 BCB02_000089 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F10 compound treatment 42699.0 -406000.0 -2.42 193711.0 -262000.0 -1.49 -2.766 -0.9731 3000859 BCB02_000090 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F11 compound treatment 523010.0 73800.0 0.44 472267.0 16100.0 0.09 0.3754 0.8364 3092512 BCB02_000091 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F12 compound treatment 275788.0 -173000.0 -1.03 391127.0 -65100.0 -0.37 -0.9913 -0.9043 3092513 BCB02_000092 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F13 compound treatment 405306.0 -43900.0 -0.26 416772.0 -39400.0 -0.22 -0.3431 -0.9971 3000860 BCB02_000093 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F14 compound treatment 404688.0 -44500.0 -0.26 451702.0 -4480.0 -0.03 -0.2053 -0.7716 3092514 BCB02_000094 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F15 compound treatment 197535.0 -252000.0 -1.5 281917.0 -174000.0 -0.99 -1.7598 -0.9799 3092515 BCB02_000095 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F16 compound treatment 71964.0 -377000.0 -2.24 127403.0 -329000.0 -1.87 -2.9095 -0.9959 3000861 BCB02_000096 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F17 mock treatment 457284.0 8100.0 0.05 307602.0 -149000.0 -0.84 -0.5634 -0.6657 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F18 mock treatment 482530.0 33300.0 0.2 348497.0 -108000.0 -0.61 -0.2927 -0.4547 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F19 mock treatment 418883.0 -30300.0 -0.18 397468.0 -58700.0 -0.33 -0.3636 -0.9582 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F20 mock treatment 112390.0 -337000.0 -2.0 449844.0 -6340.0 -0.04 -1.4428 -0.7197 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F21 mock treatment 426371.0 -22800.0 -0.14 141118.0 -315000.0 -1.79 -1.3629 -0.7585 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F22 mock treatment 447980.0 -1200.0 -0.01 419084.0 -37100.0 -0.21 -0.1542 -0.7307 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F23 mock treatment 523227.0 74000.0 0.44 464222.0 8040.0 0.05 0.3439 0.7763 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 F24 mock treatment 512709.0 63500.0 0.38 494942.0 38800.0 0.22 0.4232 0.967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G01 compound treatment 421387.0 -27800.0 -0.17 538512.0 82300.0 0.47 0.2141 0.4311 3092516 BCB02_000097 CC(C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G02 compound treatment 392398.0 -56800.0 -0.34 454077.0 -2110.0 -0.01 -0.2474 -0.7317 3000862 BCB02_000098 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G03 compound treatment 37194.0 -412000.0 -2.45 63864.0 -392000.0 -2.23 -3.3113 -0.9989 3092587 BCB02_000099 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G04 compound treatment 463483.0 14300.0 0.09 443851.0 -12300.0 -0.07 0.0106 0.096 3000863 BCB02_000100 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G05 compound treatment 453795.0 4610.0 0.03 436438.0 -19700.0 -0.11 -0.06 -0.519 3092588 BCB02_000101 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G06 compound treatment 417344.0 -31800.0 -0.19 452427.0 -3760.0 -0.02 -0.1491 -0.7819 3092589 BCB02_000102 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G07 compound treatment 354300.0 -94900.0 -0.56 426779.0 -29400.0 -0.17 -0.5175 -0.8788 3000864 BCB02_000103 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G08 compound treatment 277873.0 -171000.0 -1.02 463418.0 7230.0 0.04 -0.6918 -0.678 3092590 BCB02_000104 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G09 compound treatment 501204.0 52000.0 0.31 482411.0 26200.0 0.15 0.3244 0.9439 3092591 BCB02_000105 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G10 compound treatment 356005.0 -93200.0 -0.55 385570.0 -70600.0 -0.4 -0.6761 -0.9874 3000865 BCB02_000106 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G11 compound treatment 367755.0 -81400.0 -0.48 437836.0 -18300.0 -0.1 -0.4165 -0.8401 3092592 BCB02_000107 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G12 compound treatment 414761.0 -34400.0 -0.2 416127.0 -40100.0 -0.23 -0.3059 -0.9986 3000866 BCB02_000108 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G13 compound treatment 445683.0 -3500.0 -0.02 500158.0 44000.0 0.25 0.1621 0.646 3092593 BCB02_000109 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G14 compound treatment 361292.0 -87900.0 -0.52 181941.0 -274000.0 -1.56 -1.4726 -0.8953 3000867 BCB02_000110 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G15 compound treatment 207600.0 -242000.0 -1.44 58656.0 -398000.0 -2.26 -2.6152 -0.9761 3092594 BCB02_000111 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G16 compound treatment 415491.0 -33700.0 -0.2 287190.0 -169000.0 -0.96 -0.8213 -0.8366 3092595 BCB02_000112 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G17 mock treatment 439080.0 -10100.0 -0.06 450221.0 -5960.0 -0.03 -0.0665 -0.9633 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G18 mock treatment 426291.0 -22900.0 -0.14 449014.0 -7170.0 -0.04 -0.1252 -0.8802 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G19 mock treatment 213771.0 -235000.0 -1.4 431802.0 -24400.0 -0.14 -1.0887 -0.7733 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G20 mock treatment 432262.0 -16900.0 -0.1 483827.0 27600.0 0.16 0.0399 0.214 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G21 mock treatment 435725.0 -13500.0 -0.08 444114.0 -12100.0 -0.07 -0.1052 -0.9971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G22 mock treatment 383639.0 -65500.0 -0.39 445242.0 -10900.0 -0.06 -0.3198 -0.8097 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G23 mock treatment 379110.0 -70100.0 -0.42 195142.0 -261000.0 -1.48 -1.3446 -0.872 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 G24 mock treatment 441054.0 -8130.0 -0.05 182140.0 -274000.0 -1.56 -1.1362 -0.7287 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H01 compound treatment 456888.0 7710.0 0.05 542899.0 86700.0 0.49 0.3811 0.7695 3000868 BCB02_000113 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H02 compound treatment 214671.0 -235000.0 -1.4 464044.0 7860.0 0.04 -0.9553 -0.6841 3092596 BCB02_000114 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H03 compound treatment 514437.0 65300.0 0.39 536064.0 79900.0 0.45 0.5958 0.997 3092597 BCB02_000115 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H04 compound treatment 369440.0 -79700.0 -0.47 424569.0 -31600.0 -0.18 -0.4627 -0.9118 3000869 BCB02_000116 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H05 compound treatment 198055.0 -251000.0 -1.49 518071.0 61900.0 0.35 -0.808 -0.5262 3092598 BCB02_000117 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H06 compound treatment 288963.0 -160000.0 -0.95 394582.0 -61600.0 -0.35 -0.922 -0.9076 3000870 BCB02_000118 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H07 compound treatment 207426.0 -242000.0 -1.44 433795.0 -22400.0 -0.13 -1.1074 -0.7667 3000871 BCB02_000119 O=c1cccc(o1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H08 compound treatment 416432.0 -32800.0 -0.19 377211.0 -79000.0 -0.45 -0.4554 -0.9302 3092599 BCB02_000120 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H09 compound treatment 557119.0 108000.0 0.64 390855.0 -65300.0 -0.37 0.1915 0.2581 3000872 BCB02_000121 COc1cccc(c1)c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H10 compound treatment 318826.0 -130000.0 -0.78 297405.0 -159000.0 -0.9 -1.1871 -0.9971 3092600 BCB02_000122 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H11 compound treatment 450692.0 1510.0 0.01 476507.0 20300.0 0.12 0.0881 0.7598 1984103 BCB02_000123 Cc1ccc(cc1)c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H12 compound treatment 90824.0 -358000.0 -2.13 97791.0 -358000.0 -2.04 -2.9492 -0.9997 3092601 BCB02_000124 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H13 compound treatment 303355.0 -146000.0 -0.87 522950.0 66800.0 0.38 -0.3452 -0.3644 3000873 BCB02_000125 Clc1cccc(c1)c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H14 compound treatment 357347.0 -91800.0 -0.55 438395.0 -17800.0 -0.1 -0.458 -0.824 3000874 BCB02_000126 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H15 compound treatment 165516.0 -284000.0 -1.69 494778.0 38600.0 0.22 -1.0386 -0.6101 3000875 BCB02_000127 Clc1ccccc1c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H16 compound treatment 376895.0 -72300.0 -0.43 194862.0 -261000.0 -1.49 -1.355 -0.8758 3092602 BCB02_000128 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H17 mock treatment 422608.0 -26600.0 -0.16 438745.0 -17400.0 -0.1 -0.182 -0.9747 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H18 mock treatment 392794.0 -56400.0 -0.34 477676.0 21500.0 0.12 -0.1509 -0.4225 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H19 mock treatment 497405.0 48200.0 0.29 417019.0 -39200.0 -0.22 0.0454 0.1251 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H20 mock treatment 420215.0 -29000.0 -0.17 421749.0 -34400.0 -0.2 -0.2604 -0.998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H21 mock treatment 394514.0 -54700.0 -0.33 421634.0 -34600.0 -0.2 -0.369 -0.9708 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H22 mock treatment 153074.0 -296000.0 -1.76 426495.0 -29700.0 -0.17 -1.3655 -0.7713 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H23 mock treatment 233214.0 -216000.0 -1.29 430580.0 -25600.0 -0.15 -1.0118 -0.7822 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 H24 mock treatment 475228.0 26000.0 0.16 507901.0 51700.0 0.29 0.3176 0.9552 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I01 compound treatment 500783.0 51600.0 0.31 516679.0 60500.0 0.34 0.4604 0.9984 3092603 BCB02_000129 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I02 compound treatment 371891.0 -77300.0 -0.46 357016.0 -99200.0 -0.56 -0.724 -0.9949 3000947 BCB02_000130 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I03 compound treatment 436223.0 -13000.0 -0.08 414047.0 -42100.0 -0.24 -0.224 -0.8897 3000948 BCB02_000131 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I04 compound treatment 328594.0 -121000.0 -0.72 317170.0 -139000.0 -0.79 -1.0665 -0.9988 3000949 BCB02_000132 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I05 compound treatment 432420.0 -16800.0 -0.1 503710.0 47500.0 0.27 0.1206 0.4185 3000950 BCB02_000133 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I06 compound treatment 360326.0 -88900.0 -0.53 415549.0 -40600.0 -0.23 -0.5373 -0.9311 3000951 BCB02_000134 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I07 compound treatment 473255.0 24100.0 0.14 545160.0 89000.0 0.51 0.4591 0.873 3092604 BCB02_000135 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I08 compound treatment 431753.0 -17400.0 -0.1 468026.0 11800.0 0.07 -0.0257 -0.2081 3000952 BCB02_000136 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I09 compound treatment 511243.0 62100.0 0.37 512063.0 55900.0 0.32 0.4859 0.9972 3092605 BCB02_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I10 compound treatment 436872.0 -12300.0 -0.07 361045.0 -95100.0 -0.54 -0.4344 -0.7956 3092606 BCB02_000138 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I11 compound treatment 548444.0 99300.0 0.59 510762.0 54600.0 0.31 0.6372 0.9548 3000953 BCB02_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I12 compound treatment 554710.0 106000.0 0.63 565559.0 109000.0 0.62 0.8839 1.0 3092607 BCB02_000140 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I13 compound treatment 457827.0 8640.0 0.05 424776.0 -31400.0 -0.18 -0.0899 -0.4838 3092678 BCB02_000141 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I14 compound treatment 510048.0 60900.0 0.36 549647.0 93500.0 0.53 0.632 0.9825 3000954 BCB02_000142 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I15 compound treatment 463110.0 13900.0 0.08 448997.0 -7190.0 -0.04 0.0297 0.3214 3092679 BCB02_000143 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I16 compound treatment 298327.0 -151000.0 -0.9 216703.0 -239000.0 -1.36 -1.5978 -0.9796 3000955 BCB02_000144 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I17 mock treatment 482659.0 33500.0 0.2 492290.0 36100.0 0.21 0.2861 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I18 mock treatment 453300.0 4120.0 0.02 433832.0 -22400.0 -0.13 -0.0726 -0.5605 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I19 mock treatment 406386.0 -42800.0 -0.25 403735.0 -52500.0 -0.3 -0.391 -0.9969 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I20 mock treatment 435531.0 -13700.0 -0.08 413658.0 -42500.0 -0.24 -0.2285 -0.8955 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I21 mock treatment 272753.0 -176000.0 -1.05 417214.0 -39000.0 -0.22 -0.8992 -0.8379 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I22 mock treatment 523594.0 74400.0 0.44 428254.0 -27900.0 -0.16 0.2008 0.4269 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I23 mock treatment 459375.0 10200.0 0.06 383041.0 -73100.0 -0.42 -0.2512 -0.5977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 I24 mock treatment 495123.0 45900.0 0.27 481131.0 24900.0 0.14 0.2936 0.9533 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J01 compound treatment 431528.0 -17700.0 -0.11 536888.0 80700.0 0.46 0.2502 0.5315 3000956 BCB02_000145 CCCc1cccc(=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J02 compound treatment 422926.0 -26300.0 -0.16 495520.0 39300.0 0.22 0.0477 0.1747 3092680 BCB02_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J03 compound treatment 447236.0 -1950.0 -0.01 436571.0 -19600.0 -0.11 -0.0871 -0.7764 3000957 BCB02_000147 Fc1ccc(cc1)c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J04 compound treatment 435656.0 -13500.0 -0.08 465040.0 8850.0 0.05 -0.0213 -0.2245 3092681 BCB02_000148 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J05 compound treatment 410927.0 -38300.0 -0.23 489470.0 33300.0 0.19 -0.0271 -0.0917 3000958 BCB02_000149 O=c1cccc(o1)c2ccc(C#N)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J06 compound treatment 442430.0 -6750.0 -0.04 473475.0 17300.0 0.1 0.0411 0.387 3000959 BCB02_000150 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J07 compound treatment 431405.0 -17800.0 -0.11 600564.0 144000.0 0.82 0.5058 0.6109 3092682 BCB02_000151 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J08 compound treatment 445178.0 -4000.0 -0.02 468202.0 12000.0 0.07 0.0315 0.4348 3092683 BCB02_000152 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J09 compound treatment 505916.0 56700.0 0.34 554556.0 98400.0 0.56 0.6343 0.9708 3000960 BCB02_000153 FC(F)(F)c1ccccc1c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J10 compound treatment 453968.0 4790.0 0.03 438699.0 -17500.0 -0.1 -0.0502 -0.4851 3092684 BCB02_000154 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J11 compound treatment 420657.0 -28500.0 -0.17 403408.0 -52800.0 -0.3 -0.3323 -0.9636 3000961 BCB02_000155 O=c1cccc(o1)c2ccc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J12 compound treatment 532397.0 83200.0 0.5 491587.0 35400.0 0.2 0.4925 0.9213 3000962 BCB02_000156 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J13 compound treatment 462474.0 13300.0 0.08 452044.0 -4140.0 -0.02 0.0393 0.4759 3092685 BCB02_000157 O=c1cccc(o1)c2ccco2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J14 compound treatment 453814.0 4630.0 0.03 477870.0 21700.0 0.12 0.1067 0.8443 3092686 BCB02_000158 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J15 compound treatment 420736.0 -28400.0 -0.17 376282.0 -79900.0 -0.45 -0.441 -0.9095 3000963 BCB02_000159 O=c1cccc(CCc2ccccc2)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J16 compound treatment 445559.0 -3620.0 -0.02 491322.0 35100.0 0.2 0.126 0.6272 3092687 BCB02_000160 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J17 mock treatment 476134.0 27000.0 0.16 471309.0 15100.0 0.09 0.1742 0.9573 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J18 mock treatment 454218.0 5040.0 0.03 482775.0 26600.0 0.15 0.1281 0.8311 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J19 mock treatment 430726.0 -18500.0 -0.11 478543.0 22400.0 0.13 0.0122 0.0728 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J20 mock treatment 453368.0 4190.0 0.02 402150.0 -54000.0 -0.31 -0.1997 -0.6477 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J21 mock treatment 426395.0 -22800.0 -0.14 435420.0 -20800.0 -0.12 -0.1794 -0.9976 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J22 mock treatment 403976.0 -45200.0 -0.27 435864.0 -20300.0 -0.12 -0.272 -0.9288 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J23 mock treatment 585473.0 136000.0 0.81 484904.0 28700.0 0.16 0.689 0.8328 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 J24 mock treatment 527758.0 78600.0 0.47 487668.0 31500.0 0.18 0.4573 0.9132 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K01 compound treatment 492017.0 42800.0 0.25 599069.0 143000.0 0.81 0.7548 0.8864 3000964 BCB02_000161 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K02 compound treatment 137778.0 -311000.0 -1.85 214458.0 -242000.0 -1.37 -2.2825 -0.9892 3092688 BCB02_000162 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K03 compound treatment 476341.0 27200.0 0.16 547256.0 91100.0 0.52 0.4805 0.8857 3092689 BCB02_000163 CC(C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K04 compound treatment 253882.0 -195000.0 -1.16 330292.0 -126000.0 -0.72 -1.3281 -0.9729 3000965 BCB02_000164 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K05 compound treatment 462138.0 13000.0 0.08 434955.0 -21200.0 -0.12 -0.0308 -0.2153 3092690 BCB02_000165 CC(CC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K06 compound treatment 56219.0 -393000.0 -2.34 68855.0 -387000.0 -2.2 -3.2112 -0.9996 3000966 BCB02_000166 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K07 compound treatment 210921.0 -238000.0 -1.42 518516.0 62300.0 0.35 -0.752 -0.5145 3092691 BCB02_000167 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K08 compound treatment 399210.0 -50000.0 -0.3 446937.0 -9250.0 -0.05 -0.2475 -0.8194 3092692 BCB02_000168 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K09 compound treatment 508025.0 58800.0 0.35 535907.0 79700.0 0.45 0.5682 0.9919 3000967 BCB02_000169 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K10 compound treatment 363050.0 -86100.0 -0.51 419799.0 -36400.0 -0.21 -0.5088 -0.9204 3092693 BCB02_000170 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K11 compound treatment 436360.0 -12800.0 -0.08 452928.0 -3260.0 -0.02 -0.0671 -0.854 3000968 BCB02_000171 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K12 compound treatment 140349.0 -309000.0 -1.84 191477.0 -265000.0 -1.51 -2.3641 -0.9951 3092694 BCB02_000172 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K13 compound treatment 476416.0 27200.0 0.16 492096.0 35900.0 0.2 0.259 0.9934 3092695 BCB02_000173 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K14 compound treatment 405294.0 -43900.0 -0.26 386546.0 -69600.0 -0.4 -0.4647 -0.9796 3000969 BCB02_000174 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K15 compound treatment 453441.0 4260.0 0.03 480067.0 23900.0 0.14 0.114 0.8248 3092696 BCB02_000175 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K16 compound treatment 481812.0 32600.0 0.19 407245.0 -48900.0 -0.28 -0.0595 -0.1753 3000970 BCB02_000176 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)N(CC)CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K17 mock treatment 505741.0 56600.0 0.34 497574.0 41400.0 0.24 0.4044 0.9847 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K18 mock treatment 451035.0 1850.0 0.01 542286.0 86100.0 0.49 0.354 0.7228 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K19 mock treatment 404928.0 -44300.0 -0.26 508856.0 52700.0 0.3 0.0256 0.0641 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K20 mock treatment 414996.0 -34200.0 -0.2 470394.0 14200.0 0.08 -0.0867 -0.3962 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K21 mock treatment 451251.0 2070.0 0.01 464339.0 8150.0 0.05 0.0415 0.8649 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K22 mock treatment 385062.0 -64100.0 -0.38 446760.0 -9430.0 -0.05 -0.3077 -0.7986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K23 mock treatment 521167.0 72000.0 0.43 432403.0 -23800.0 -0.14 0.2073 0.4614 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 K24 mock treatment 451582.0 2400.0 0.01 462596.0 6410.0 0.04 0.0359 0.9163 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L01 compound treatment 285556.0 -164000.0 -0.97 535632.0 79400.0 0.45 -0.3691 -0.3438 3000971 BCB02_000177 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L02 compound treatment 411649.0 -37500.0 -0.22 504497.0 48300.0 0.27 0.0363 0.1026 3092697 BCB02_000178 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L03 compound treatment 171482.0 -278000.0 -1.65 604752.0 149000.0 0.84 -0.5712 -0.3078 3000972 BCB02_000179 O=c1cccc(/C=C/c2ccccc2)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L04 compound treatment 405790.0 -43400.0 -0.26 496860.0 40700.0 0.23 -0.019 -0.0549 3092698 BCB02_000180 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L05 compound treatment 297737.0 -151000.0 -0.9 344831.0 -111000.0 -0.63 -1.0851 -0.9851 3000973 BCB02_000181 O=c1cccc(o1)c2cccc3ccccc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L06 compound treatment 274056.0 -175000.0 -1.04 494041.0 37900.0 0.22 -0.5848 -0.5495 3092699 BCB02_000182 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L07 compound treatment 259845.0 -189000.0 -1.13 165434.0 -291000.0 -1.65 -1.9659 -0.9825 3000974 BCB02_000183 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L08 compound treatment 301877.0 -147000.0 -0.88 532392.0 76200.0 0.43 -0.3135 -0.3205 3092700 BCB02_000184 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L09 compound treatment 335240.0 -114000.0 -0.68 398843.0 -57300.0 -0.33 -0.7101 -0.9437 3092701 BCB02_000185 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L10 compound treatment 335847.0 -113000.0 -0.67 405005.0 -51200.0 -0.29 -0.6828 -0.9294 3000975 BCB02_000186 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L11 compound treatment 525075.0 75900.0 0.45 542525.0 86300.0 0.49 0.6666 0.9991 3092771 BCB02_000187 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L12 compound treatment 522831.0 73600.0 0.44 530925.0 74700.0 0.43 0.6105 0.9999 3000976 BCB02_000188 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L13 compound treatment 67066.0 -382000.0 -2.27 73668.0 -383000.0 -2.18 -3.1462 -0.9998 3092772 BCB02_000189 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L14 compound treatment 469511.0 20300.0 0.12 429022.0 -27200.0 -0.15 -0.0237 -0.1207 3092773 BCB02_000190 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L15 compound treatment 218282.0 -231000.0 -1.37 128392.0 -328000.0 -1.86 -2.2898 -0.9887 3000977 BCB02_000191 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L16 compound treatment 484785.0 35600.0 0.21 593498.0 137000.0 0.78 0.702 0.8676 3092774 BCB02_000192 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L17 mock treatment 440747.0 -8440.0 -0.05 494934.0 38700.0 0.22 0.1203 0.5324 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L18 mock treatment 472135.0 23000.0 0.14 516624.0 60400.0 0.34 0.3396 0.9183 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L19 mock treatment 419494.0 -29700.0 -0.18 497842.0 41700.0 0.24 0.0426 0.1441 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L20 mock treatment 396522.0 -52700.0 -0.31 480069.0 23900.0 0.14 -0.1256 -0.3676 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L21 mock treatment 442403.0 -6780.0 -0.04 478002.0 21800.0 0.12 0.0592 0.4538 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L22 mock treatment 421900.0 -27300.0 -0.16 454636.0 -1550.0 -0.01 -0.121 -0.7444 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L23 mock treatment 421351.0 -27800.0 -0.17 450341.0 -5840.0 -0.03 -0.1406 -0.8324 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 L24 mock treatment 269073.0 -180000.0 -1.07 447354.0 -8830.0 -0.05 -0.7935 -0.7394 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M01 compound treatment 516257.0 67100.0 0.4 596820.0 141000.0 0.8 0.8478 0.9485 3000978 BCB02_000193 CC1(C)[C@H]2C[C@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M02 compound treatment 222841.0 -226000.0 -1.35 386624.0 -69600.0 -0.4 -1.2322 -0.8777 3001047 BCB02_000194 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M03 compound treatment 317124.0 -132000.0 -0.79 330135.0 -126000.0 -0.72 -1.0626 -0.9989 3092775 BCB02_000195 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M04 compound treatment 200823.0 -248000.0 -1.48 525379.0 69200.0 0.39 -0.7669 -0.5014 3001048 BCB02_000196 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M05 compound treatment 502999.0 53800.0 0.32 533620.0 77400.0 0.44 0.5379 0.9878 3092776 BCB02_000197 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)[N+](=O)[O-])C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M06 compound treatment 458599.0 9420.0 0.06 423916.0 -32300.0 -0.18 -0.0901 -0.4697 3001049 BCB02_000198 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M07 compound treatment 558213.0 109000.0 0.65 532118.0 75900.0 0.43 0.7642 0.9804 3092777 BCB02_000199 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M08 compound treatment 537853.0 88700.0 0.53 531757.0 75600.0 0.43 0.677 0.9948 3092778 BCB02_000200 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M09 compound treatment 514675.0 65500.0 0.39 396981.0 -59200.0 -0.34 0.0375 0.0729 3001050 BCB02_000201 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M10 compound treatment 357995.0 -91200.0 -0.54 298313.0 -158000.0 -0.9 -1.0186 -0.9709 3001168 BCB02_000202 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M11 compound treatment 525086.0 75900.0 0.45 538627.0 82400.0 0.47 0.6509 0.9998 3092779 BCB02_000203 COc1ccc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M12 compound treatment 366756.0 -82400.0 -0.49 330625.0 -126000.0 -0.71 -0.8518 -0.9832 3092780 BCB02_000204 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M13 compound treatment 439609.0 -9570.0 -0.06 486114.0 29900.0 0.17 0.0801 0.4461 3001169 BCB02_000205 COc1ccc(NN2C3C(C=CC2C(O)C4=CC[C@H](CC4)C(=C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M14 compound treatment 408266.0 -40900.0 -0.24 434490.0 -21700.0 -0.12 -0.2594 -0.9504 3092781 BCB02_000206 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M15 compound treatment 581305.0 132000.0 0.79 501625.0 45400.0 0.26 0.7387 0.8925 3001170 BCB02_000207 COc1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M16 mock treatment 548639.0 99500.0 0.59 556368.0 100000.0 0.57 0.8214 0.9998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M17 mock treatment 520628.0 71400.0 0.43 513185.0 57000.0 0.32 0.5299 0.991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M18 mock treatment 467423.0 18200.0 0.11 548122.0 91900.0 0.52 0.4465 0.8361 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M19 mock treatment 499243.0 50100.0 0.3 558729.0 103000.0 0.58 0.623 0.9514 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M20 mock treatment 469905.0 20700.0 0.12 582316.0 126000.0 0.72 0.5944 0.8167 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M21 mock treatment 422641.0 -26500.0 -0.16 538106.0 81900.0 0.47 0.2177 0.4426 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M22 mock treatment 424553.0 -24600.0 -0.15 541389.0 85200.0 0.48 0.239 0.4721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M23 mock treatment 481977.0 32800.0 0.2 457323.0 1140.0 0.01 0.1426 0.7301 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 M24 mock treatment 518933.0 69800.0 0.42 499846.0 43700.0 0.25 0.4691 0.9698 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N01 compound treatment 156282.0 -293000.0 -1.74 143478.0 -313000.0 -1.78 -2.49 -1.0 3092782 BCB02_000208 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N02 compound treatment 473714.0 24500.0 0.15 459291.0 3110.0 0.02 0.1157 0.7869 3092783 BCB02_000209 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N03 compound treatment 277652.0 -172000.0 -1.02 187713.0 -268000.0 -1.53 -1.8014 -0.9808 3001171 BCB02_000210 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N04 compound treatment 497858.0 48700.0 0.29 507817.0 51600.0 0.29 0.4125 1.0 3092784 BCB02_000211 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N05 compound treatment 46194.0 -403000.0 -2.4 59734.0 -396000.0 -2.25 -3.2901 -0.9995 3001172 BCB02_000212 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N06 compound treatment 541374.0 92200.0 0.55 541099.0 84900.0 0.48 0.7294 0.998 3092785 BCB02_000213 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N07 compound treatment 411035.0 -38100.0 -0.23 371910.0 -84300.0 -0.48 -0.4994 -0.9418 3092786 BCB02_000214 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N08 compound treatment 559175.0 110000.0 0.65 277588.0 -179000.0 -1.02 -0.2553 -0.2113 3001173 BCB02_000215 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N09 compound treatment 495823.0 46600.0 0.28 157801.0 -298000.0 -1.7 -1.0036 -0.5837 3092787 BCB02_000216 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N10 compound treatment 558872.0 110000.0 0.65 577054.0 121000.0 0.69 0.9476 0.9997 3001174 BCB02_000217 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N11 compound treatment 572311.0 123000.0 0.73 510574.0 54400.0 0.31 0.7369 0.9264 3092788 BCB02_000218 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N12 compound treatment 610521.0 161000.0 0.96 543022.0 86800.0 0.49 1.0281 0.9522 3092789 BCB02_000219 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N13 compound treatment 164794.0 -284000.0 -1.69 146109.0 -310000.0 -1.76 -2.4436 -0.9998 3001175 BCB02_000220 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N14 compound treatment 465641.0 16500.0 0.1 551667.0 95500.0 0.54 0.4532 0.8214 3092790 BCB02_000221 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N15 compound treatment 584470.0 135000.0 0.81 506577.0 50400.0 0.29 0.772 0.9033 3001176 BCB02_000222 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N16 mock treatment 557730.0 109000.0 0.65 529236.0 73100.0 0.42 0.7505 0.9772 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N17 mock treatment 527145.0 78000.0 0.46 577716.0 122000.0 0.69 0.8168 0.9812 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N18 mock treatment 512160.0 63000.0 0.37 519210.0 63000.0 0.36 0.5185 0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N19 mock treatment 512017.0 62800.0 0.37 547854.0 91700.0 0.52 0.633 0.9867 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N20 mock treatment 439317.0 -9870.0 -0.06 507522.0 51300.0 0.29 0.1649 0.5538 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N21 mock treatment 488888.0 39700.0 0.24 476103.0 19900.0 0.11 0.2472 0.9433 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N22 mock treatment 487199.0 38000.0 0.23 208534.0 -248000.0 -1.41 -0.8359 -0.586 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N23 mock treatment 492096.0 42900.0 0.26 512740.0 56600.0 0.32 0.408 0.9935 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 N24 mock treatment 465187.0 16000.0 0.1 496147.0 40000.0 0.23 0.228 0.9255 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O01 compound treatment 599721.0 151000.0 0.9 558938.0 103000.0 0.58 1.0467 0.9786 3092791 BCB02_000223 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O02 compound treatment 100519.0 -349000.0 -2.08 91468.0 -365000.0 -2.07 -2.9339 -1.0 3001177 BCB02_000224 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O03 compound treatment 398634.0 -50500.0 -0.3 445102.0 -11100.0 -0.06 -0.2573 -0.8371 3092792 BCB02_000225 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)c(OCc5ccccc5)c4)C(=O)N(C6CCCCC6)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O04 compound treatment 53669.0 -396000.0 -2.35 70824.0 -385000.0 -2.19 -3.214 -0.9994 3001178 BCB02_000226 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O05 compound treatment 279101.0 -170000.0 -1.01 310515.0 -146000.0 -0.83 -1.3015 -0.995 3092860 BCB02_000227 COc1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O06 compound treatment 258923.0 -190000.0 -1.13 216626.0 -240000.0 -1.36 -1.764 -0.9958 3001179 BCB02_000228 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O07 compound treatment 527880.0 78700.0 0.47 438498.0 -17700.0 -0.1 0.2601 0.5429 3092861 BCB02_000229 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O08 compound treatment 62639.0 -387000.0 -2.3 65378.0 -391000.0 -2.22 -3.1982 -0.9999 3001245 BCB02_000230 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O09 compound treatment 459399.0 10200.0 0.06 403886.0 -52300.0 -0.3 -0.1673 -0.5511 3092862 BCB02_000231 COc1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O10 compound treatment 403683.0 -45500.0 -0.27 367386.0 -88800.0 -0.5 -0.5485 -0.9573 3001246 BCB02_000232 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O11 compound treatment 552471.0 103000.0 0.61 584018.0 128000.0 0.73 0.9487 0.9965 3092863 BCB02_000233 Cc1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O12 compound treatment 587272.0 138000.0 0.82 592730.0 137000.0 0.78 1.1302 0.9996 3001247 BCB02_000234 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O13 compound treatment 335249.0 -114000.0 -0.68 312212.0 -144000.0 -0.82 -1.0584 -0.9956 3092864 BCB02_000235 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O14 compound treatment 525573.0 76400.0 0.45 445152.0 -11000.0 -0.06 0.2771 0.6038 3001248 BCB02_000236 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O15 compound treatment 618857.0 170000.0 1.01 622388.0 166000.0 0.95 1.3824 0.9995 3092865 BCB02_000237 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O16 mock treatment 627804.0 179000.0 1.06 566093.0 110000.0 0.63 1.1936 0.9679 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O17 mock treatment 602832.0 154000.0 0.91 642833.0 187000.0 1.06 1.3971 0.9972 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O18 mock treatment 589301.0 140000.0 0.83 512953.0 56800.0 0.32 0.8179 0.9147 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O19 mock treatment 504117.0 54900.0 0.33 327653.0 -129000.0 -0.73 -0.2857 -0.3568 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O20 mock treatment 474039.0 24900.0 0.15 557795.0 102000.0 0.58 0.5132 0.8604 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O21 mock treatment 490155.0 41000.0 0.24 532842.0 76700.0 0.44 0.4807 0.9623 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O22 mock treatment 484203.0 35000.0 0.21 581866.0 126000.0 0.71 0.6528 0.8768 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O23 mock treatment 459648.0 10500.0 0.06 487243.0 31100.0 0.18 0.1689 0.902 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 O24 mock treatment 453583.0 4400.0 0.03 580945.0 125000.0 0.71 0.5202 0.7327 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P01 compound treatment 611790.0 163000.0 0.97 585941.0 130000.0 0.74 1.2061 0.991 3001249 BCB02_000238 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P02 compound treatment 225398.0 -224000.0 -1.33 531486.0 75300.0 0.43 -0.639 -0.4567 3092866 BCB02_000239 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P03 compound treatment 483879.0 34700.0 0.21 516059.0 59900.0 0.34 0.3868 0.9713 3001250 BCB02_000240 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P04 compound treatment 210862.0 -238000.0 -1.42 395664.0 -60500.0 -0.34 -1.2463 -0.8539 3092867 BCB02_000241 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P05 compound treatment 538517.0 89300.0 0.53 493476.0 37300.0 0.21 0.5259 0.9188 3001251 BCB02_000242 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P06 compound treatment 276437.0 -173000.0 -1.03 232544.0 -224000.0 -1.27 -1.6263 -0.9944 3092868 BCB02_000243 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P07 compound treatment 579870.0 131000.0 0.78 527176.0 71000.0 0.4 0.8354 0.9534 3001252 BCB02_000244 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P08 compound treatment 221088.0 -228000.0 -1.36 411950.0 -44200.0 -0.25 -1.1378 -0.8241 3092869 BCB02_000245 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P09 compound treatment 564588.0 115000.0 0.69 557347.0 101000.0 0.58 0.8924 0.9961 3001253 BCB02_000246 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P10 compound treatment 355328.0 -93900.0 -0.56 324272.0 -132000.0 -0.75 -0.9254 -0.9895 3092870 BCB02_000247 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P11 compound treatment 574807.0 126000.0 0.75 560290.0 104000.0 0.59 0.9473 0.9933 3001254 BCB02_000248 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P12 compound treatment 540051.0 90900.0 0.54 459156.0 2970.0 0.02 0.3943 0.7288 3092871 BCB02_000249 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P13 compound treatment 492363.0 43200.0 0.26 465853.0 9670.0 0.05 0.2206 0.8394 3001255 BCB02_000250 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P14 compound treatment 600612.0 151000.0 0.9 572783.0 117000.0 0.66 1.1061 0.9886 3092774 BCB02_000251 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P15 compound treatment 641628.0 192000.0 1.15 546062.0 89900.0 0.51 1.1713 0.9339 3092872 BCB02_000252 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P16 mock treatment 587554.0 138000.0 0.82 535089.0 78900.0 0.45 0.8996 0.9592 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P17 mock treatment 510234.0 61100.0 0.36 462032.0 5850.0 0.03 0.2804 0.7686 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P18 mock treatment 595934.0 147000.0 0.87 530759.0 74600.0 0.42 0.9174 0.9449 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P19 mock treatment 507623.0 58400.0 0.35 547010.0 90800.0 0.52 0.6112 0.9815 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P20 mock treatment 546354.0 97200.0 0.58 571904.0 116000.0 0.66 0.8742 0.9979 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P21 mock treatment 503983.0 54800.0 0.33 556882.0 101000.0 0.57 0.6355 0.9644 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P22 mock treatment 522193.0 73000.0 0.43 567254.0 111000.0 0.63 0.7539 0.9833 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P23 mock treatment 485487.0 36300.0 0.22 513400.0 57200.0 0.33 0.3828 0.9802 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2088 P24 mock treatment 573958.0 125000.0 0.74 575346.0 119000.0 0.68 1.0043 0.999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A01 compound treatment 130781.0 -340000.0 -2.03 152137.0 -360000.0 -2.05 -2.8796 -1.0 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A02 compound treatment 201059.0 -270000.0 -1.61 234149.0 -278000.0 -1.58 -2.2541 -1.0 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A03 compound treatment 416436.0 -54600.0 -0.33 502060.0 -10100.0 -0.06 -0.2704 -0.8189 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A04 compound treatment 416324.0 -54800.0 -0.33 446470.0 -65700.0 -0.37 -0.4944 -0.9977 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A05 compound treatment 444870.0 -26200.0 -0.16 516172.0 4050.0 0.02 -0.094 -0.5962 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A06 compound treatment 390541.0 -80500.0 -0.48 399698.0 -112000.0 -0.64 -0.791 -0.9899 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A07 compound treatment 366165.0 -105000.0 -0.62 78943.0 -433000.0 -2.46 -2.1834 -0.8592 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A08 compound treatment 438602.0 -32500.0 -0.19 474861.0 -37300.0 -0.21 -0.2865 -0.9989 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A09 compound treatment 478951.0 7870.0 0.05 254845.0 -257000.0 -1.46 -1.0014 -0.6841 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A10 compound treatment 324391.0 -147000.0 -0.87 276732.0 -235000.0 -1.34 -1.5638 -0.9785 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A11 compound treatment 127940.0 -343000.0 -2.04 139226.0 -373000.0 -2.12 -2.9435 -0.9998 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A12 compound treatment 78440.0 -393000.0 -2.34 211456.0 -301000.0 -1.71 -2.8613 -0.9882 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A13 mock treatment 492996.0 21900.0 0.13 201143.0 -311000.0 -1.77 -1.1582 -0.6532 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A14 mock treatment 542603.0 71500.0 0.43 479186.0 -32900.0 -0.19 0.1686 0.3625 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A15 compound treatment 114075.0 -357000.0 -2.12 131316.0 -381000.0 -2.17 -3.0336 -1.0 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A16 compound treatment 353666.0 -117000.0 -0.7 364963.0 -147000.0 -0.84 -1.0858 -0.996 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A17 compound treatment 511312.0 40200.0 0.24 520870.0 8750.0 0.05 0.2045 0.8362 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A18 compound treatment 341760.0 -129000.0 -0.77 341857.0 -170000.0 -0.97 -1.2289 -0.9935 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A19 compound treatment 313384.0 -158000.0 -0.94 250391.0 -262000.0 -1.49 -1.7161 -0.9753 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A20 compound treatment 124530.0 -347000.0 -2.06 134455.0 -378000.0 -2.15 -2.977 -0.9998 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A21 compound treatment 330125.0 -141000.0 -0.84 353748.0 -158000.0 -0.9 -1.23 -0.9994 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A22 compound treatment 539178.0 68100.0 0.41 488229.0 -23900.0 -0.14 0.1905 0.4457 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A23 compound treatment 441165.0 -29900.0 -0.18 403761.0 -108000.0 -0.62 -0.5616 -0.8756 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 A24 compound treatment 211724.0 -259000.0 -1.54 238216.0 -274000.0 -1.56 -2.1928 -1.0 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B01 compound treatment 297629.0 -173000.0 -1.03 207466.0 -305000.0 -1.73 -1.955 -0.9694 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B02 compound treatment 398892.0 -72200.0 -0.43 456596.0 -55500.0 -0.32 -0.5271 -0.9885 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B03 compound treatment 216601.0 -254000.0 -1.51 266488.0 -246000.0 -1.4 -2.0586 -0.9992 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B04 compound treatment 534527.0 63400.0 0.38 587730.0 75600.0 0.43 0.571 0.9979 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B05 compound treatment 415284.0 -55800.0 -0.33 452840.0 -59300.0 -0.34 -0.4732 -1.0 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B06 compound treatment 418649.0 -52400.0 -0.31 605151.0 93000.0 0.53 0.1535 0.2498 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B07 compound treatment 421983.0 -49100.0 -0.29 349112.0 -163000.0 -0.93 -0.8621 -0.887 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B08 compound treatment 288572.0 -183000.0 -1.09 234695.0 -277000.0 -1.58 -1.8836 -0.9834 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B09 compound treatment 436033.0 -35000.0 -0.21 414570.0 -97600.0 -0.55 -0.5397 -0.9107 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B10 compound treatment 264084.0 -207000.0 -1.23 341524.0 -171000.0 -0.97 -1.5571 -0.993 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B11 compound treatment 73224.0 -398000.0 -2.37 232229.0 -280000.0 -1.59 -2.7998 -0.9813 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B12 compound treatment 479145.0 8070.0 0.05 470646.0 -41500.0 -0.24 -0.1328 -0.5518 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B13 mock treatment 482870.0 11800.0 0.07 622731.0 111000.0 0.63 0.4944 0.7812 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B14 mock treatment 480217.0 9140.0 0.05 541780.0 29700.0 0.17 0.1577 0.89 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B15 compound treatment 500661.0 29600.0 0.18 457988.0 -54100.0 -0.31 -0.0932 -0.2628 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B16 compound treatment 448503.0 -22600.0 -0.13 387081.0 -125000.0 -0.71 -0.5978 -0.8261 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B17 compound treatment 58791.0 -412000.0 -2.45 60792.0 -451000.0 -2.57 -3.5499 -0.9997 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B18 compound treatment 436015.0 -35100.0 -0.21 453966.0 -58200.0 -0.33 -0.3814 -0.9753 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B19 compound treatment 180899.0 -290000.0 -1.73 112360.0 -400000.0 -2.27 -2.8287 -0.9908 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B20 compound treatment 332721.0 -138000.0 -0.82 240154.0 -272000.0 -1.55 -1.6759 -0.9565 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B21 compound treatment 262826.0 -208000.0 -1.24 277465.0 -235000.0 -1.33 -1.82 -0.9993 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B22 compound treatment 422825.0 -48300.0 -0.29 457147.0 -55000.0 -0.31 -0.4241 -0.9991 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B23 compound treatment 413201.0 -57900.0 -0.34 474668.0 -37500.0 -0.21 -0.3942 -0.9733 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 B24 compound treatment 455078.0 -16000.0 -0.1 437059.0 -75100.0 -0.43 -0.3692 -0.8441 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C01 compound treatment 255201.0 -216000.0 -1.28 109925.0 -402000.0 -2.29 -2.5258 -0.9628 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C02 compound treatment 428350.0 -42700.0 -0.25 388939.0 -123000.0 -0.7 -0.6751 -0.9059 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C03 compound treatment 402464.0 -68600.0 -0.41 399003.0 -113000.0 -0.64 -0.7436 -0.9759 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C04 compound treatment 451653.0 -19400.0 -0.12 468895.0 -43200.0 -0.25 -0.2556 -0.9408 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C05 compound treatment 410538.0 -60500.0 -0.36 414224.0 -97900.0 -0.56 -0.6484 -0.9778 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C06 compound treatment 196222.0 -275000.0 -1.64 478875.0 -33200.0 -0.19 -1.2904 -0.7836 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C07 compound treatment 245265.0 -226000.0 -1.34 292439.0 -220000.0 -1.25 -1.8337 -0.9993 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C08 compound treatment 419714.0 -51400.0 -0.31 534568.0 22400.0 0.13 -0.1259 -0.38 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C09 compound treatment 416230.0 -54800.0 -0.33 419642.0 -92500.0 -0.53 -0.6027 -0.9737 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C10 compound treatment 134681.0 -336000.0 -2.0 121276.0 -391000.0 -2.22 -2.9873 -0.9986 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C11 mock treatment 462695.0 -8380.0 -0.05 453138.0 -59000.0 -0.34 -0.2725 -0.8034 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C12 mock treatment 417677.0 -53400.0 -0.32 492728.0 -19400.0 -0.11 -0.3027 -0.8998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C13 compound treatment 50513.0 -421000.0 -2.5 55647.0 -456000.0 -2.6 -3.6054 -0.9998 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C14 compound treatment 261093.0 -210000.0 -1.25 237592.0 -275000.0 -1.56 -1.9876 -0.9939 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C15 mock treatment 466900.0 -4180.0 -0.02 458748.0 -53400.0 -0.3 -0.2322 -0.7625 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C16 mock treatment 461736.0 -9340.0 -0.06 415486.0 -96600.0 -0.55 -0.4279 -0.7747 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C17 compound treatment 58964.0 -412000.0 -2.45 58473.0 -454000.0 -2.58 -3.5585 -0.9997 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C18 compound treatment 278817.0 -192000.0 -1.14 271006.0 -241000.0 -1.37 -1.7786 -0.996 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C19 compound treatment 52875.0 -418000.0 -2.49 54256.0 -458000.0 -2.6 -3.6011 -0.9997 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C20 compound treatment 164194.0 -307000.0 -1.83 208053.0 -304000.0 -1.73 -2.5142 -0.9996 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C21 compound treatment 213103.0 -258000.0 -1.54 190367.0 -322000.0 -1.83 -2.3794 -0.9962 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C22 compound treatment 281224.0 -190000.0 -1.13 230786.0 -281000.0 -1.6 -1.9302 -0.9855 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C23 compound treatment 486798.0 15700.0 0.09 546093.0 34000.0 0.19 0.2028 0.9446 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 C24 compound treatment 50874.0 -420000.0 -2.5 57813.0 -454000.0 -2.58 -3.5952 -0.9999 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D01 compound treatment 517210.0 46100.0 0.27 501078.0 -11000.0 -0.06 0.1497 0.5316 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D02 compound treatment 545323.0 74200.0 0.44 569947.0 57800.0 0.33 0.545 0.9894 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D03 compound treatment 353700.0 -117000.0 -0.7 426429.0 -85700.0 -0.49 -0.8385 -0.9845 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D04 compound treatment 303952.0 -167000.0 -0.99 333589.0 -179000.0 -1.02 -1.4212 -0.9999 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D05 compound treatment 365478.0 -106000.0 -0.63 437018.0 -75100.0 -0.43 -0.7464 -0.9823 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D06 compound treatment 101570.0 -370000.0 -2.2 173424.0 -339000.0 -1.93 -2.9169 -0.9978 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D07 compound treatment 456022.0 -15100.0 -0.09 529680.0 17600.0 0.1 0.0072 0.054 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D08 compound treatment 188472.0 -283000.0 -1.68 211361.0 -301000.0 -1.71 -2.3987 -1.0 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D09 compound treatment 55162.0 -416000.0 -2.48 60443.0 -452000.0 -2.57 -3.5666 -0.9998 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D10 compound treatment 433772.0 -37300.0 -0.22 278038.0 -234000.0 -1.33 -1.0983 -0.8138 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D11 mock treatment 438282.0 -32800.0 -0.2 474119.0 -38000.0 -0.22 -0.2908 -0.9987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D12 mock treatment 430320.0 -40800.0 -0.24 452452.0 -59700.0 -0.34 -0.4115 -0.9865 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D13 compound treatment 53777.0 -417000.0 -2.48 53040.0 -459000.0 -2.61 -3.6022 -0.9997 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D14 compound treatment 265440.0 -206000.0 -1.22 286677.0 -225000.0 -1.28 -1.7719 -0.9997 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D15 mock treatment 442303.0 -28800.0 -0.17 480522.0 -31600.0 -0.18 -0.2482 -0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D16 mock treatment 377275.0 -93800.0 -0.56 387709.0 -124000.0 -0.71 -0.895 -0.9931 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D17 compound treatment 65358.0 -406000.0 -2.41 59208.0 -453000.0 -2.58 -3.5286 -0.9995 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D18 compound treatment 318290.0 -153000.0 -0.91 384387.0 -128000.0 -0.73 -1.1566 -0.9938 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D19 compound treatment 332594.0 -138000.0 -0.82 303558.0 -209000.0 -1.19 -1.4214 -0.9842 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D20 compound treatment 356591.0 -114000.0 -0.68 370141.0 -142000.0 -0.81 -1.0527 -0.9964 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D21 compound treatment 87213.0 -384000.0 -2.28 61442.0 -451000.0 -2.56 -3.4277 -0.9984 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D22 compound treatment 531553.0 60500.0 0.36 518657.0 6540.0 0.04 0.2808 0.776 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D23 compound treatment 294123.0 -177000.0 -1.05 191215.0 -321000.0 -1.82 -2.0351 -0.9659 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 D24 compound treatment 351870.0 -119000.0 -0.71 324465.0 -188000.0 -1.07 -1.2563 -0.9803 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E01 mock treatment 611466.0 140000.0 0.84 579618.0 67500.0 0.38 0.8622 0.9377 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E02 mock treatment 480553.0 9480.0 0.06 548036.0 35900.0 0.2 0.1843 0.8698 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E03 compound treatment 374133.0 -96900.0 -0.58 128654.0 -383000.0 -2.18 -1.9499 -0.8644 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E04 compound treatment 302868.0 -168000.0 -1.0 88790.0 -423000.0 -2.41 -2.4101 -0.9244 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E05 compound treatment 478880.0 7800.0 0.05 313851.0 -198000.0 -1.13 -0.7644 -0.6774 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E06 compound treatment 371141.0 -99900.0 -0.59 296224.0 -216000.0 -1.23 -1.2887 -0.9446 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E07 compound treatment 46230.0 -425000.0 -2.53 64559.0 -448000.0 -2.55 -3.5876 -1.0 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E08 compound treatment 266685.0 -204000.0 -1.22 373869.0 -138000.0 -0.79 -1.4161 -0.9777 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E09 mock treatment 442067.0 -29000.0 -0.17 487861.0 -24300.0 -0.14 -0.2196 -0.9938 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E10 mock treatment 275527.0 -196000.0 -1.16 458353.0 -53800.0 -0.31 -1.0391 -0.8636 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E11 compound treatment 52777.0 -418000.0 -2.49 72591.0 -440000.0 -2.5 -3.5277 -1.0 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E12 compound treatment 366436.0 -105000.0 -0.62 392715.0 -119000.0 -0.68 -0.9205 -0.9991 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E13 compound treatment 53214.0 -418000.0 -2.49 58702.0 -453000.0 -2.58 -3.5818 -0.9998 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E14 compound treatment 316439.0 -155000.0 -0.92 345804.0 -166000.0 -0.95 -1.3195 -0.9999 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E15 compound treatment 126378.0 -345000.0 -2.05 129330.0 -383000.0 -2.18 -2.9899 -0.9996 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E16 compound treatment 298483.0 -173000.0 -1.03 325237.0 -187000.0 -1.06 -1.4778 -0.9999 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E17 mock treatment 447317.0 -23800.0 -0.14 485222.0 -26900.0 -0.15 -0.2082 -0.9992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E18 mock treatment 430790.0 -40300.0 -0.24 459111.0 -53000.0 -0.3 -0.3827 -0.9936 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E19 compound treatment 449057.0 -22000.0 -0.13 508245.0 -3880.0 -0.02 -0.1083 -0.8146 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E20 compound treatment 371580.0 -99500.0 -0.59 395563.0 -117000.0 -0.66 -0.8874 -0.9984 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E21 compound treatment 294153.0 -177000.0 -1.05 327008.0 -185000.0 -1.05 -1.4889 -1.0 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E22 compound treatment 458786.0 -12300.0 -0.07 439139.0 -73000.0 -0.42 -0.3452 -0.8191 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E23 compound treatment 169493.0 -302000.0 -1.79 155778.0 -356000.0 -2.03 -2.7021 -0.9982 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 E24 compound treatment 241645.0 -229000.0 -1.37 238278.0 -274000.0 -1.56 -2.0667 -0.9979 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F01 mock treatment 572286.0 101000.0 0.6 580874.0 68800.0 0.39 0.7024 0.9781 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F02 mock treatment 249867.0 -221000.0 -1.32 553726.0 41600.0 0.24 -0.7636 -0.5709 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F03 compound treatment 133859.0 -337000.0 -2.01 158816.0 -353000.0 -2.01 -2.8398 -1.0 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F04 compound treatment 85415.0 -386000.0 -2.3 271411.0 -241000.0 -1.37 -2.5909 -0.9695 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F05 compound treatment 61919.0 -409000.0 -2.44 65513.0 -447000.0 -2.54 -3.5177 -0.9998 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F06 compound treatment 326343.0 -145000.0 -0.86 413185.0 -98900.0 -0.56 -1.0069 -0.9787 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F07 compound treatment 326889.0 -144000.0 -0.86 337717.0 -174000.0 -0.99 -1.3081 -0.9974 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F08 compound treatment 254116.0 -217000.0 -1.29 312865.0 -199000.0 -1.13 -1.7143 -0.9979 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F09 mock treatment 453475.0 -17600.0 -0.1 527860.0 15700.0 0.09 -0.0108 -0.0783 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F10 mock treatment 436554.0 -34500.0 -0.21 501651.0 -10500.0 -0.06 -0.1874 -0.876 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F11 compound treatment 56492.0 -415000.0 -2.47 63139.0 -449000.0 -2.55 -3.5501 -0.9999 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F12 compound treatment 426996.0 -44100.0 -0.26 455060.0 -57100.0 -0.32 -0.415 -0.9944 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F13 compound treatment 55124.0 -416000.0 -2.48 56458.0 -456000.0 -2.59 -3.5827 -0.9997 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F14 compound treatment 141706.0 -329000.0 -1.96 187159.0 -325000.0 -1.85 -2.6928 -0.9996 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F15 compound treatment 71332.0 -400000.0 -2.38 84726.0 -427000.0 -2.43 -3.4009 -0.9999 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F16 compound treatment 260771.0 -210000.0 -1.25 274719.0 -237000.0 -1.35 -1.8397 -0.9993 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F17 mock treatment 497923.0 26800.0 0.16 441500.0 -70600.0 -0.4 -0.171 -0.3956 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F18 mock treatment 414086.0 -57000.0 -0.34 470668.0 -41500.0 -0.24 -0.4065 -0.9842 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F19 compound treatment 202524.0 -269000.0 -1.6 215976.0 -296000.0 -1.68 -2.321 -0.9997 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F20 compound treatment 473001.0 1920.0 0.01 526013.0 13900.0 0.08 0.064 0.8012 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F21 compound treatment 472373.0 1300.0 0.01 560793.0 48700.0 0.28 0.2012 0.7265 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F22 compound treatment 440379.0 -30700.0 -0.18 522199.0 10100.0 0.06 -0.0887 -0.463 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F23 compound treatment 458575.0 -12500.0 -0.07 509718.0 -2400.0 -0.01 -0.0623 -0.8232 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 F24 compound treatment 540823.0 69700.0 0.42 517936.0 5820.0 0.03 0.3169 0.761 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G01 compound treatment 559086.0 88000.0 0.52 560519.0 48400.0 0.28 0.565 0.9549 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G02 compound treatment 508655.0 37600.0 0.22 457839.0 -54300.0 -0.31 -0.0601 -0.1578 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G03 mock treatment 262984.0 -208000.0 -1.24 520418.0 8300.0 0.05 -0.8424 -0.6797 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G04 mock treatment 459299.0 -11800.0 -0.07 412281.0 -99800.0 -0.57 -0.451 -0.7884 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G05 compound treatment 177558.0 -294000.0 -1.75 377642.0 -134000.0 -0.76 -1.776 -0.9313 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G06 compound treatment 321593.0 -149000.0 -0.89 321359.0 -191000.0 -1.08 -1.3962 -0.9952 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G07 compound treatment 330352.0 -141000.0 -0.84 363569.0 -149000.0 -0.84 -1.1896 -1.0 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G08 compound treatment 372006.0 -99100.0 -0.59 349292.0 -163000.0 -0.93 -1.0717 -0.9762 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G09 compound treatment 385564.0 -85500.0 -0.51 413593.0 -98500.0 -0.56 -0.7561 -0.9988 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G10 compound treatment 350290.0 -121000.0 -0.72 382541.0 -130000.0 -0.74 -1.0294 -0.9999 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G11 compound treatment 156172.0 -315000.0 -1.87 234308.0 -278000.0 -1.58 -2.4423 -0.9964 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G12 compound treatment 102989.0 -368000.0 -2.19 63085.0 -449000.0 -2.55 -3.3547 -0.9971 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G13 compound treatment 54834.0 -416000.0 -2.48 54968.0 -457000.0 -2.6 -3.5899 -0.9997 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G14 compound treatment 493822.0 22700.0 0.14 470289.0 -41800.0 -0.24 -0.0725 -0.2649 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G15 compound treatment 479294.0 8220.0 0.05 265255.0 -247000.0 -1.4 -0.9581 -0.6821 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G16 compound treatment 133789.0 -337000.0 -2.01 108517.0 -404000.0 -2.3 -3.0424 -0.9978 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G17 compound treatment 366172.0 -105000.0 -0.62 381763.0 -130000.0 -0.74 -0.9657 -0.9964 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G18 compound treatment 326674.0 -144000.0 -0.86 98458.0 -414000.0 -2.35 -2.2711 -0.9068 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G19 mock treatment 437792.0 -33300.0 -0.2 112499.0 -400000.0 -2.27 -1.747 -0.7658 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G20 mock treatment 476389.0 5310.0 0.03 480240.0 -31900.0 -0.18 -0.1058 -0.5751 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G21 compound treatment 460853.0 -10200.0 -0.06 224076.0 -288000.0 -1.64 -1.2013 -0.7329 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G22 compound treatment 120177.0 -351000.0 -2.09 78955.0 -433000.0 -2.46 -3.2185 -0.9966 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G23 compound treatment 476975.0 5900.0 0.04 471496.0 -40600.0 -0.23 -0.1385 -0.5929 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 G24 compound treatment 171410.0 -300000.0 -1.78 102790.0 -409000.0 -2.33 -2.9071 -0.9913 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H01 compound treatment 292556.0 -179000.0 -1.06 280064.0 -232000.0 -1.32 -1.6844 -0.9942 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H02 compound treatment 352628.0 -118000.0 -0.7 423227.0 -88900.0 -0.51 -0.8559 -0.9867 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H03 mock treatment 491449.0 20400.0 0.12 605571.0 93500.0 0.53 0.4615 0.8467 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H04 mock treatment 474797.0 3720.0 0.02 454354.0 -57800.0 -0.33 -0.2166 -0.658 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H05 compound treatment 343595.0 -127000.0 -0.76 438549.0 -73600.0 -0.42 -0.8323 -0.9607 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H06 compound treatment 443739.0 -27300.0 -0.16 498782.0 -13300.0 -0.08 -0.1687 -0.9397 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H07 compound treatment 115149.0 -356000.0 -2.12 118035.0 -394000.0 -2.24 -3.0825 -0.9996 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H08 compound treatment 455232.0 -15800.0 -0.09 451145.0 -61000.0 -0.35 -0.3119 -0.8679 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H09 compound treatment 152280.0 -319000.0 -1.9 111736.0 -400000.0 -2.28 -2.9516 -0.9959 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H10 compound treatment 389815.0 -81300.0 -0.48 413055.0 -99100.0 -0.56 -0.7403 -0.9971 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H11 compound treatment 302527.0 -169000.0 -1.0 299511.0 -213000.0 -1.21 -1.5642 -0.9957 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H12 compound treatment 298415.0 -173000.0 -1.03 194055.0 -318000.0 -1.81 -2.0056 -0.9641 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H13 compound treatment 53295.0 -418000.0 -2.49 55597.0 -457000.0 -2.6 -3.5939 -0.9998 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H14 compound treatment 62337.0 -409000.0 -2.43 56709.0 -455000.0 -2.59 -3.5514 -0.9995 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H15 compound treatment 66116.0 -405000.0 -2.41 69333.0 -443000.0 -2.52 -3.4847 -0.9998 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H16 compound treatment 265493.0 -206000.0 -1.22 498196.0 -13900.0 -0.08 -0.9212 -0.7513 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H17 compound treatment 387644.0 -83400.0 -0.5 181353.0 -331000.0 -1.88 -1.6812 -0.8642 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H18 compound treatment 456207.0 -14900.0 -0.09 467737.0 -44400.0 -0.25 -0.2411 -0.9013 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H19 mock treatment 509195.0 38100.0 0.23 432835.0 -79300.0 -0.45 -0.1584 -0.3139 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H20 mock treatment 389600.0 -81500.0 -0.48 512442.0 321.0 0.0 -0.3416 -0.7044 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H21 compound treatment 222735.0 -248000.0 -1.48 228657.0 -283000.0 -1.61 -2.1849 -0.9991 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H22 compound treatment 253449.0 -218000.0 -1.3 256949.0 -255000.0 -1.45 -1.9419 -0.9984 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H23 compound treatment 309623.0 -161000.0 -0.96 300596.0 -212000.0 -1.2 -1.53 -0.9938 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 H24 compound treatment 68790.0 -402000.0 -2.39 67624.0 -444000.0 -2.53 -3.4803 -0.9996 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I01 compound treatment 474988.0 3910.0 0.02 439836.0 -72300.0 -0.41 -0.2742 -0.666 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I02 compound treatment 313027.0 -158000.0 -0.94 303743.0 -208000.0 -1.18 -1.503 -0.9935 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I03 compound treatment 464299.0 -6780.0 -0.04 437409.0 -74700.0 -0.42 -0.329 -0.7708 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I04 compound treatment 491220.0 20100.0 0.12 502862.0 -9260.0 -0.05 0.0475 0.3631 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I05 mock treatment 441067.0 -30000.0 -0.18 531260.0 19100.0 0.11 -0.0493 -0.2359 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I06 mock treatment 469709.0 -1370.0 -0.01 490952.0 -21200.0 -0.12 -0.0909 -0.7532 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I07 compound treatment 199552.0 -272000.0 -1.62 376498.0 -136000.0 -0.77 -1.688 -0.9427 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I08 compound treatment 499080.0 28000.0 0.17 504078.0 -8040.0 -0.05 0.0855 0.4948 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I09 compound treatment 355441.0 -116000.0 -0.69 400804.0 -111000.0 -0.63 -0.9343 -0.9991 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I10 compound treatment 536370.0 65300.0 0.39 493816.0 -18300.0 -0.1 0.2012 0.5001 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I11 compound treatment 476897.0 5820.0 0.03 488765.0 -23400.0 -0.13 -0.0694 -0.5058 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I12 compound treatment 378305.0 -92800.0 -0.55 446382.0 -65700.0 -0.37 -0.6548 -0.982 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I13 compound treatment 438706.0 -32400.0 -0.19 502464.0 -9660.0 -0.05 -0.1751 -0.8739 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I14 compound treatment 375465.0 -95600.0 -0.57 364711.0 -147000.0 -0.84 -0.9951 -0.9822 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I15 compound treatment 207827.0 -263000.0 -1.57 192921.0 -319000.0 -1.82 -2.3914 -0.9973 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I16 compound treatment 167791.0 -303000.0 -1.8 152865.0 -359000.0 -2.04 -2.7209 -0.9981 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I17 compound treatment 549971.0 78900.0 0.47 188412.0 -324000.0 -1.84 -0.9697 -0.5104 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I18 compound treatment 457426.0 -13700.0 -0.08 588934.0 76800.0 0.44 0.2514 0.5659 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I19 compound treatment 485574.0 14500.0 0.09 442869.0 -69300.0 -0.39 -0.2175 -0.5394 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I20 compound treatment 249823.0 -221000.0 -1.32 239022.0 -273000.0 -1.55 -2.0293 -0.9966 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I21 mock treatment 445409.0 -25700.0 -0.15 431343.0 -80800.0 -0.46 -0.4328 -0.8941 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I22 mock treatment 510181.0 39100.0 0.23 429559.0 -82600.0 -0.47 -0.1674 -0.3195 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I23 compound treatment 233141.0 -238000.0 -1.42 217246.0 -295000.0 -1.68 -2.187 -0.9965 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 I24 compound treatment 443980.0 -27100.0 -0.16 548616.0 36500.0 0.21 0.0327 0.1245 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J01 compound treatment 58185.0 -413000.0 -2.46 58435.0 -454000.0 -2.58 -3.5619 -0.9997 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J02 compound treatment 353937.0 -117000.0 -0.7 303569.0 -209000.0 -1.19 -1.3316 -0.9679 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J03 compound treatment 403226.0 -67900.0 -0.4 387707.0 -124000.0 -0.71 -0.7858 -0.9646 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J04 compound treatment 499842.0 28800.0 0.17 594201.0 82100.0 0.47 0.4511 0.9073 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J05 mock treatment 486534.0 15500.0 0.09 489238.0 -22900.0 -0.13 -0.027 -0.1692 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J06 mock treatment 423906.0 -47200.0 -0.28 434373.0 -77700.0 -0.44 -0.5111 -0.976 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J07 compound treatment 458453.0 -12600.0 -0.08 404869.0 -107000.0 -0.61 -0.4844 -0.7883 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J08 compound treatment 292640.0 -178000.0 -1.06 331063.0 -181000.0 -1.03 -1.479 -0.9999 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J09 compound treatment 361723.0 -109000.0 -0.65 113479.0 -399000.0 -2.27 -2.0632 -0.8748 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J10 compound treatment 136140.0 -335000.0 -1.99 80602.0 -432000.0 -2.45 -3.1447 -0.9947 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J11 compound treatment 60657.0 -410000.0 -2.44 64580.0 -448000.0 -2.55 -3.5268 -0.9998 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J12 compound treatment 424884.0 -46200.0 -0.27 515370.0 3250.0 0.02 -0.1813 -0.6581 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J13 compound treatment 53945.0 -417000.0 -2.48 56759.0 -455000.0 -2.59 -3.5865 -0.9998 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J14 compound treatment 74329.0 -397000.0 -2.36 53064.0 -459000.0 -2.61 -3.5156 -0.9987 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J15 compound treatment 421034.0 -50000.0 -0.3 433452.0 -78700.0 -0.45 -0.5269 -0.9805 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J16 compound treatment 400299.0 -70800.0 -0.42 374971.0 -137000.0 -0.78 -0.8494 -0.9582 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J17 compound treatment 342972.0 -128000.0 -0.76 335023.0 -177000.0 -1.01 -1.2512 -0.9906 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J18 compound treatment 54372.0 -417000.0 -2.48 57400.0 -455000.0 -2.59 -3.5821 -0.9998 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J19 compound treatment 435755.0 -35300.0 -0.21 391219.0 -121000.0 -0.69 -0.6348 -0.883 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J20 compound treatment 99707.0 -371000.0 -2.21 99270.0 -413000.0 -2.35 -3.223 -0.9995 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J21 mock treatment 521766.0 50700.0 0.3 523521.0 11400.0 0.06 0.2592 0.8399 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J22 mock treatment 434672.0 -36400.0 -0.22 418743.0 -93400.0 -0.53 -0.5287 -0.9218 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J23 compound treatment 528980.0 57900.0 0.34 506785.0 -5340.0 -0.03 0.2222 0.6424 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 J24 compound treatment 211566.0 -260000.0 -1.54 239252.0 -273000.0 -1.55 -2.1893 -1.0 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K01 compound treatment 575428.0 104000.0 0.62 539719.0 27600.0 0.16 0.5501 0.8588 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K02 compound treatment 443670.0 -27400.0 -0.16 421815.0 -90300.0 -0.51 -0.4785 -0.888 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K03 compound treatment 433566.0 -37500.0 -0.22 409691.0 -102000.0 -0.58 -0.5697 -0.9133 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K04 compound treatment 70234.0 -401000.0 -2.39 67497.0 -445000.0 -2.53 -3.4748 -0.9996 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K05 compound treatment 114775.0 -356000.0 -2.12 90050.0 -422000.0 -2.4 -3.1966 -0.9981 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K06 compound treatment 161278.0 -310000.0 -1.84 83161.0 -429000.0 -2.44 -3.0286 -0.9905 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K07 mock treatment 509613.0 38500.0 0.23 564366.0 52200.0 0.3 0.3723 0.9918 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K08 mock treatment 477792.0 6710.0 0.04 559683.0 47600.0 0.27 0.2195 0.8029 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K09 compound treatment 533670.0 62600.0 0.37 414781.0 -97300.0 -0.55 -0.128 -0.1919 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K10 compound treatment 473614.0 2540.0 0.02 252784.0 -259000.0 -1.47 -1.0322 -0.6998 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K11 compound treatment 244516.0 -227000.0 -1.35 270768.0 -241000.0 -1.37 -1.924 -1.0 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K12 compound treatment 376371.0 -94700.0 -0.56 422022.0 -90100.0 -0.51 -0.7609 -0.9989 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K13 compound treatment 487952.0 16900.0 0.1 559736.0 47600.0 0.27 0.2625 0.9089 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K14 compound treatment 428099.0 -43000.0 -0.26 431813.0 -80300.0 -0.46 -0.5038 -0.9625 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K15 mock treatment 510167.0 39100.0 0.23 595253.0 83100.0 0.47 0.4988 0.9467 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K16 mock treatment 509514.0 38400.0 0.23 492983.0 -19100.0 -0.11 0.0848 0.3347 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K17 compound treatment 502941.0 31900.0 0.19 477624.0 -34500.0 -0.2 -0.0046 -0.017 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K18 compound treatment 485277.0 14200.0 0.08 241517.0 -271000.0 -1.54 -1.0284 -0.6673 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K19 compound treatment 60596.0 -410000.0 -2.44 59277.0 -453000.0 -2.58 -3.5484 -0.9997 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K20 compound treatment 266165.0 -205000.0 -1.22 309469.0 -203000.0 -1.15 -1.6772 -0.9996 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K21 compound treatment 534194.0 63100.0 0.38 487378.0 -24700.0 -0.14 0.1661 0.4141 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K22 compound treatment 272080.0 -199000.0 -1.18 223704.0 -288000.0 -1.64 -1.9972 -0.9872 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K23 mock treatment 366992.0 -104000.0 -0.62 624234.0 112000.0 0.64 0.0128 0.0144 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 K24 mock treatment 509711.0 38600.0 0.23 535383.0 23300.0 0.13 0.2561 0.9655 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L01 compound treatment 318640.0 -152000.0 -0.91 322235.0 -190000.0 -1.08 -1.4051 -0.9962 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L02 compound treatment 510367.0 39300.0 0.23 355166.0 -157000.0 -0.89 -0.4658 -0.5048 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L03 compound treatment 357976.0 -113000.0 -0.67 346449.0 -166000.0 -0.94 -1.1422 -0.9864 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L04 compound treatment 372337.0 -98700.0 -0.59 435654.0 -76500.0 -0.43 -0.723 -0.989 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L05 compound treatment 378570.0 -92500.0 -0.55 368588.0 -144000.0 -0.82 -0.9665 -0.9816 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L06 compound treatment 266253.0 -205000.0 -1.22 284230.0 -228000.0 -1.3 -1.7783 -0.9995 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L07 mock treatment 534694.0 63600.0 0.38 551380.0 39300.0 0.22 0.4256 0.9683 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L08 mock treatment 605052.0 134000.0 0.8 451991.0 -60100.0 -0.34 0.322 0.3712 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L09 compound treatment 92775.0 -378000.0 -2.25 140098.0 -372000.0 -2.12 -3.088 -0.9995 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L10 compound treatment 556520.0 85400.0 0.51 648878.0 137000.0 0.78 0.9095 0.9788 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L11 compound treatment 79385.0 -392000.0 -2.33 67283.0 -445000.0 -2.53 -3.4371 -0.9992 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L12 compound treatment 382536.0 -88500.0 -0.53 350739.0 -161000.0 -0.92 -1.0215 -0.9653 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L13 compound treatment 208400.0 -263000.0 -1.56 211302.0 -301000.0 -1.71 -2.3151 -0.999 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L14 compound treatment 113344.0 -358000.0 -2.13 154844.0 -357000.0 -2.03 -2.9421 -0.9997 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L15 mock treatment 506074.0 35000.0 0.21 615063.0 103000.0 0.59 0.5612 0.9032 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L16 mock treatment 434199.0 -36900.0 -0.22 503614.0 -8510.0 -0.05 -0.1894 -0.8427 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L17 compound treatment 410442.0 -60600.0 -0.36 399669.0 -112000.0 -0.64 -0.7074 -0.9633 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L18 compound treatment 55422.0 -416000.0 -2.47 67946.0 -444000.0 -2.53 -3.5353 -0.9999 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L19 compound treatment 377992.0 -93100.0 -0.55 331141.0 -181000.0 -1.03 -1.1195 -0.9578 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L20 compound treatment 504786.0 33700.0 0.2 444429.0 -67700.0 -0.38 -0.1303 -0.3003 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L21 compound treatment 184926.0 -286000.0 -1.7 159682.0 -352000.0 -2.0 -2.6214 -0.9967 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L22 compound treatment 267246.0 -204000.0 -1.21 360439.0 -152000.0 -0.86 -1.4677 -0.986 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L23 mock treatment 457408.0 -13700.0 -0.08 556642.0 44500.0 0.25 0.1215 0.4569 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 L24 mock treatment 489285.0 18200.0 0.11 526475.0 14400.0 0.08 0.1343 0.9902 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M01 compound treatment 459586.0 -11500.0 -0.07 447988.0 -64100.0 -0.36 -0.3062 -0.8253 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M02 compound treatment 464288.0 -6790.0 -0.04 435962.0 -76200.0 -0.43 -0.3348 -0.7697 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M03 compound treatment 508173.0 37100.0 0.22 541629.0 29500.0 0.17 0.2748 0.9908 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M04 compound treatment 428026.0 -43100.0 -0.26 435256.0 -76900.0 -0.44 -0.4903 -0.9676 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M05 compound treatment 514909.0 43800.0 0.26 572561.0 60400.0 0.34 0.4275 0.9907 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M06 compound treatment 372979.0 -98100.0 -0.58 386200.0 -126000.0 -0.72 -0.9192 -0.9949 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M07 compound treatment 557266.0 86200.0 0.51 618747.0 107000.0 0.61 0.7915 0.9965 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M08 compound treatment 208220.0 -263000.0 -1.56 211762.0 -300000.0 -1.71 -2.314 -0.999 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M09 mock treatment 532823.0 61700.0 0.37 525800.0 13700.0 0.08 0.3148 0.8382 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M10 mock treatment 531640.0 60600.0 0.36 602375.0 90300.0 0.51 0.6178 0.985 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M11 compound treatment 581189.0 110000.0 0.66 612944.0 101000.0 0.57 0.8688 0.9978 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M12 compound treatment 133619.0 -337000.0 -2.01 129969.0 -382000.0 -2.17 -2.9568 -0.9992 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M13 mock treatment 523727.0 52600.0 0.31 278622.0 -233000.0 -1.33 -0.7174 -0.5258 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M14 mock treatment 497174.0 26100.0 0.16 574080.0 62000.0 0.35 0.359 0.9322 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M15 compound treatment 547376.0 76300.0 0.45 572818.0 60700.0 0.35 0.5652 0.9908 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M16 compound treatment 579524.0 108000.0 0.65 247596.0 -265000.0 -1.5 -0.6073 -0.371 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M17 compound treatment 480180.0 9100.0 0.05 522004.0 9880.0 0.06 0.078 0.9998 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M18 compound treatment 527421.0 56300.0 0.34 465666.0 -46500.0 -0.26 0.0503 0.1178 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M19 compound treatment 504066.0 33000.0 0.2 534532.0 22400.0 0.13 0.2289 0.9781 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M20 compound treatment 602983.0 132000.0 0.79 516179.0 4060.0 0.02 0.5714 0.7276 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M21 compound treatment 508859.0 37800.0 0.22 505185.0 -6940.0 -0.04 0.1311 0.5743 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M22 compound treatment 441912.0 -29200.0 -0.17 518096.0 5980.0 0.03 -0.0987 -0.5581 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M23 compound treatment 43741.0 -427000.0 -2.54 49137.0 -463000.0 -2.63 -3.6601 -0.9999 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 M24 compound treatment 126754.0 -344000.0 -2.05 103994.0 -408000.0 -2.32 -3.0901 -0.9981 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N01 compound treatment 338701.0 -132000.0 -0.79 253473.0 -259000.0 -1.47 -1.5971 -0.9572 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N02 compound treatment 63316.0 -408000.0 -2.43 67101.0 -445000.0 -2.53 -3.5055 -0.9998 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N03 compound treatment 62469.0 -409000.0 -2.43 63245.0 -449000.0 -2.55 -3.5245 -0.9997 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N04 compound treatment 509219.0 38100.0 0.23 551714.0 39600.0 0.23 0.3197 1.0 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N05 compound treatment 290624.0 -180000.0 -1.07 278950.0 -233000.0 -1.33 -1.697 -0.9945 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N06 compound treatment 487986.0 16900.0 0.1 586121.0 74000.0 0.42 0.3687 0.8522 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N07 compound treatment 351061.0 -120000.0 -0.71 413955.0 -98200.0 -0.56 -0.8998 -0.9926 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N08 compound treatment 99739.0 -371000.0 -2.21 132135.0 -380000.0 -2.16 -3.0907 -0.9999 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N09 mock treatment 494626.0 23500.0 0.14 605691.0 93600.0 0.53 0.4754 0.8639 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N10 mock treatment 488994.0 17900.0 0.11 552918.0 40800.0 0.23 0.2394 0.9378 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N11 compound treatment 126611.0 -344000.0 -2.05 166360.0 -346000.0 -1.97 -2.84 -0.9998 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N12 compound treatment 466019.0 -5060.0 -0.03 545659.0 33500.0 0.19 0.1136 0.5882 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N13 mock treatment 526162.0 55100.0 0.33 553385.0 41300.0 0.23 0.3977 0.9866 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N14 mock treatment 495128.0 24100.0 0.14 549366.0 37200.0 0.21 0.251 0.9818 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N15 compound treatment 301715.0 -169000.0 -1.01 311015.0 -201000.0 -1.14 -1.5214 -0.998 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N16 compound treatment 489392.0 18300.0 0.11 586576.0 74500.0 0.42 0.3765 0.8611 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N17 compound treatment 113298.0 -358000.0 -2.13 134787.0 -377000.0 -2.15 -3.023 -1.0 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N18 compound treatment 197844.0 -273000.0 -1.63 266361.0 -246000.0 -1.4 -2.1381 -0.9972 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N19 compound treatment 51812.0 -419000.0 -2.5 57719.0 -454000.0 -2.58 -3.5916 -0.9998 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N20 compound treatment 381021.0 -90100.0 -0.54 347259.0 -165000.0 -0.94 -1.0419 -0.9648 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N21 compound treatment 116894.0 -354000.0 -2.11 80539.0 -432000.0 -2.45 -3.226 -0.9971 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N22 compound treatment 512332.0 41300.0 0.25 614685.0 103000.0 0.58 0.586 0.9261 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N23 compound treatment 171032.0 -300000.0 -1.79 258469.0 -254000.0 -1.44 -2.2826 -0.9944 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 N24 compound treatment 190894.0 -280000.0 -1.67 193514.0 -319000.0 -1.81 -2.4603 -0.9991 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O01 compound treatment 219843.0 -251000.0 -1.5 103048.0 -409000.0 -2.33 -2.7022 -0.9772 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O02 compound treatment 389501.0 -81600.0 -0.49 470366.0 -41800.0 -0.24 -0.5112 -0.9459 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O03 compound treatment 57057.0 -414000.0 -2.46 61888.0 -450000.0 -2.56 -3.5528 -0.9998 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O04 compound treatment 418173.0 -52900.0 -0.31 489866.0 -22300.0 -0.13 -0.3121 -0.9198 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O05 compound treatment 511711.0 40600.0 0.24 612917.0 101000.0 0.57 0.5763 0.9264 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O06 compound treatment 397546.0 -73500.0 -0.44 501902.0 -10200.0 -0.06 -0.3505 -0.794 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O07 compound treatment 524567.0 53500.0 0.32 585176.0 73100.0 0.42 0.5189 0.9914 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O08 compound treatment 333295.0 -138000.0 -0.82 409412.0 -103000.0 -0.58 -0.9928 -0.9862 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O09 compound treatment 57173.0 -414000.0 -2.46 62063.0 -450000.0 -2.56 -3.5516 -0.9998 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O10 compound treatment 369334.0 -102000.0 -0.61 430274.0 -81800.0 -0.47 -0.7573 -0.9916 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O11 mock treatment 621315.0 150000.0 0.89 570115.0 58000.0 0.33 0.8654 0.9081 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O12 mock treatment 481725.0 10600.0 0.06 615045.0 103000.0 0.59 0.4587 0.7791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O13 compound treatment 255329.0 -216000.0 -1.28 360174.0 -152000.0 -0.86 -1.5189 -0.9814 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O14 compound treatment 516171.0 45100.0 0.27 636187.0 124000.0 0.71 0.6887 0.9123 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O15 compound treatment 454953.0 -16100.0 -0.1 507209.0 -4910.0 -0.03 -0.0876 -0.8765 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O16 compound treatment 463554.0 -7520.0 -0.04 486830.0 -25300.0 -0.14 -0.1334 -0.8853 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O17 compound treatment 101699.0 -369000.0 -2.2 65872.0 -446000.0 -2.54 -3.3489 -0.9974 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O18 compound treatment 460648.0 -10400.0 -0.06 467663.0 -44500.0 -0.25 -0.2227 -0.8553 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O19 compound treatment 56192.0 -415000.0 -2.47 32602.0 -480000.0 -2.73 -3.6742 -0.9988 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O20 compound treatment 74997.0 -396000.0 -2.36 65687.0 -446000.0 -2.54 -3.462 -0.9993 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O21 compound treatment 56058.0 -415000.0 -2.47 38899.0 -473000.0 -2.69 -3.6494 -0.9991 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O22 compound treatment 489716.0 18600.0 0.11 608304.0 96200.0 0.55 0.4652 0.8335 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O23 compound treatment 344364.0 -127000.0 -0.75 253010.0 -259000.0 -1.47 -1.5752 -0.9516 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 O24 compound treatment 239064.0 -232000.0 -1.38 193134.0 -319000.0 -1.81 -2.2591 -0.9909 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P01 compound treatment 316506.0 -155000.0 -0.92 234671.0 -277000.0 -1.58 -1.7661 -0.967 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P02 compound treatment 267808.0 -203000.0 -1.21 284652.0 -227000.0 -1.29 -1.7701 -0.9994 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P03 compound treatment 337593.0 -133000.0 -0.79 377135.0 -135000.0 -0.77 -1.1045 -0.9999 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P04 compound treatment 88671.0 -382000.0 -2.28 91832.0 -420000.0 -2.39 -3.2993 -0.9997 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P05 compound treatment 73000.0 -398000.0 -2.37 80061.0 -432000.0 -2.46 -3.4126 -0.9998 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P06 compound treatment 192024.0 -279000.0 -1.66 204798.0 -307000.0 -1.75 -2.4101 -0.9997 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P07 compound treatment 318006.0 -153000.0 -0.91 368803.0 -143000.0 -0.82 -1.2205 -0.9985 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P08 compound treatment 383953.0 -87100.0 -0.52 481902.0 -30200.0 -0.17 -0.4882 -0.8937 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P09 compound treatment 471455.0 377.0 0.0 719441.0 207000.0 1.18 0.8353 0.7085 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P10 compound treatment 585382.0 114000.0 0.68 544376.0 32300.0 0.18 0.6107 0.8668 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P11 mock treatment 506013.0 34900.0 0.21 615713.0 104000.0 0.59 0.5636 0.9021 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P12 mock treatment 496617.0 25500.0 0.15 611098.0 99000.0 0.56 0.5055 0.867 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P13 compound treatment 231654.0 -239000.0 -1.42 79806.0 -432000.0 -2.46 -2.746 -0.9664 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P14 compound treatment 495715.0 24600.0 0.15 616336.0 104000.0 0.59 0.5227 0.8562 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P15 compound treatment 414494.0 -56600.0 -0.34 565464.0 53300.0 0.3 -0.0236 -0.0521 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P16 compound treatment 517744.0 46700.0 0.28 582979.0 70900.0 0.4 0.4813 0.9835 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P17 compound treatment 300594.0 -170000.0 -1.01 384630.0 -127000.0 -0.73 -1.2301 -0.9864 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P18 compound treatment 508691.0 37600.0 0.22 585605.0 73500.0 0.42 0.4538 0.9572 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P19 compound treatment 49557.0 -422000.0 -2.51 63873.0 -448000.0 -2.55 -3.5763 -1.0 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P20 compound treatment 162622.0 -308000.0 -1.84 90179.0 -422000.0 -2.4 -2.9948 -0.9913 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P21 compound treatment 170892.0 -300000.0 -1.79 280754.0 -231000.0 -1.32 -2.1936 -0.9887 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P22 compound treatment 542976.0 71900.0 0.43 247665.0 -264000.0 -1.5 -0.7608 -0.4866 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P23 compound treatment 246547.0 -225000.0 -1.34 248731.0 -263000.0 -1.5 -2.004 -0.9984 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2093 P24 compound treatment 204122.0 -267000.0 -1.59 202223.0 -310000.0 -1.76 -2.3696 -0.9987 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A01 compound treatment 72317.0 -426000.0 -2.53 379902.0 -87300.0 -0.5 -2.142 -0.8299 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A02 compound treatment 239391.0 -259000.0 -1.54 295991.0 -171000.0 -0.97 -1.7763 -0.9756 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A03 compound treatment 343324.0 -155000.0 -0.92 311825.0 -155000.0 -0.88 -1.2752 -0.9998 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A04 compound treatment 565022.0 67100.0 0.4 397469.0 -69700.0 -0.4 0.0021 0.0038 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A05 compound treatment 523499.0 25600.0 0.15 592986.0 126000.0 0.72 0.6136 0.8387 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A06 compound treatment 128372.0 -370000.0 -2.2 66980.0 -400000.0 -2.28 -3.1644 -0.9999 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A07 compound treatment 53961.0 -444000.0 -2.64 359276.0 -108000.0 -0.61 -2.3022 -0.8487 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A08 compound treatment 122514.0 -375000.0 -2.23 291424.0 -176000.0 -1.0 -2.2865 -0.9342 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A09 compound treatment 517207.0 19300.0 0.11 521784.0 54600.0 0.31 0.3008 0.9083 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A10 compound treatment 340175.0 -158000.0 -0.94 305762.0 -161000.0 -0.92 -1.3129 -0.9999 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A11 compound treatment 130337.0 -368000.0 -2.19 105232.0 -362000.0 -2.06 -3.0023 -0.9995 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A12 compound treatment 311406.0 -187000.0 -1.11 290353.0 -177000.0 -1.01 -1.4959 -0.9988 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A13 mock treatment 590687.0 92800.0 0.55 497529.0 30400.0 0.17 0.5125 0.886 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A14 mock treatment 597719.0 99800.0 0.59 442662.0 -24500.0 -0.14 0.3214 0.5269 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A15 compound treatment 327942.0 -170000.0 -1.01 83014.0 -384000.0 -2.18 -2.2601 -0.9388 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A16 compound treatment 292437.0 -205000.0 -1.22 92928.0 -374000.0 -2.13 -2.3696 -0.9654 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A17 compound treatment 566559.0 68600.0 0.41 482585.0 15400.0 0.09 0.3508 0.8398 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A18 compound treatment 59535.0 -438000.0 -2.61 92815.0 -374000.0 -2.13 -3.3502 -0.9949 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A19 compound treatment 63385.0 -435000.0 -2.59 68430.0 -399000.0 -2.27 -3.432 -0.9979 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A20 compound treatment 322732.0 -175000.0 -1.04 232164.0 -235000.0 -1.34 -1.6822 -0.9925 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A21 compound treatment 347788.0 -150000.0 -0.89 225524.0 -242000.0 -1.37 -1.6035 -0.9783 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A22 compound treatment 598856.0 101000.0 0.6 537718.0 70600.0 0.4 0.7085 0.9808 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A23 compound treatment 572363.0 74400.0 0.44 515236.0 48100.0 0.27 0.5066 0.9731 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 A24 compound treatment 604730.0 107000.0 0.64 572118.0 105000.0 0.6 0.8715 0.9995 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B01 compound treatment 444177.0 -53800.0 -0.32 532396.0 65200.0 0.37 0.0361 0.0737 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B02 compound treatment 379133.0 -119000.0 -0.71 399959.0 -67200.0 -0.38 -0.7702 -0.9583 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B03 compound treatment 265026.0 -233000.0 -1.39 312127.0 -155000.0 -0.88 -1.6035 -0.9761 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B04 compound treatment 107592.0 -390000.0 -2.32 128136.0 -339000.0 -1.93 -3.0059 -0.9957 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B05 compound treatment 406300.0 -91600.0 -0.55 450042.0 -17100.0 -0.1 -0.4544 -0.8204 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B06 compound treatment 251108.0 -247000.0 -1.47 344778.0 -122000.0 -0.7 -1.5308 -0.9418 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B07 compound treatment 261109.0 -237000.0 -1.41 276363.0 -191000.0 -1.09 -1.7638 -0.9917 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B08 compound treatment 277129.0 -221000.0 -1.31 404960.0 -62200.0 -0.35 -1.1793 -0.8666 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B09 compound treatment 352390.0 -146000.0 -0.87 335399.0 -132000.0 -0.75 -1.1423 -0.9974 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B10 compound treatment 218736.0 -279000.0 -1.66 208805.0 -258000.0 -1.47 -2.2138 -0.9981 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B11 compound treatment 158798.0 -339000.0 -2.02 138033.0 -329000.0 -1.87 -2.7506 -0.9993 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B12 compound treatment 77551.0 -420000.0 -2.5 63266.0 -404000.0 -2.3 -3.3932 -0.9991 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B13 mock treatment 521030.0 23100.0 0.14 434760.0 -32400.0 -0.18 -0.0331 -0.1438 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B14 mock treatment 533442.0 35500.0 0.21 448854.0 -18300.0 -0.1 0.0758 0.3219 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B15 compound treatment 442296.0 -55600.0 -0.33 365958.0 -101000.0 -0.58 -0.6411 -0.9655 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B16 compound treatment 200758.0 -297000.0 -1.77 133552.0 -334000.0 -1.9 -2.5921 -0.9994 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B17 compound treatment 263427.0 -235000.0 -1.4 247761.0 -219000.0 -1.25 -1.8691 -0.9984 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B18 compound treatment 270449.0 -227000.0 -1.35 290406.0 -177000.0 -1.01 -1.6681 -0.9893 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B19 compound treatment 98417.0 -400000.0 -2.38 75217.0 -392000.0 -2.23 -3.2573 -0.9995 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B20 compound treatment 78263.0 -420000.0 -2.5 220654.0 -247000.0 -1.4 -2.7573 -0.9627 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B21 compound treatment 167601.0 -330000.0 -1.97 74067.0 -393000.0 -2.24 -2.9708 -0.9979 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B22 compound treatment 222408.0 -276000.0 -1.64 199180.0 -268000.0 -1.52 -2.2371 -0.9993 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B23 compound treatment 61548.0 -436000.0 -2.6 63015.0 -404000.0 -2.3 -3.4615 -0.9981 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 B24 compound treatment 340673.0 -157000.0 -0.94 376208.0 -91000.0 -0.52 -1.0275 -0.9609 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C01 compound treatment 316257.0 -182000.0 -1.08 512603.0 45400.0 0.26 -0.5818 -0.5234 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C02 compound treatment 258606.0 -239000.0 -1.42 124126.0 -343000.0 -1.95 -2.3865 -0.9881 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C03 compound treatment 483853.0 -14100.0 -0.08 397884.0 -69300.0 -0.39 -0.3378 -0.8387 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C04 compound treatment 536016.0 38100.0 0.23 326641.0 -141000.0 -0.8 -0.4048 -0.4873 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C05 compound treatment 322461.0 -175000.0 -1.04 299980.0 -167000.0 -0.95 -1.4107 -0.9989 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C06 compound treatment 138765.0 -359000.0 -2.14 347713.0 -119000.0 -0.68 -1.9918 -0.8881 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C07 compound treatment 390570.0 -107000.0 -0.64 477365.0 10200.0 0.06 -0.4108 -0.6403 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C08 compound treatment 350949.0 -147000.0 -0.87 457301.0 -9860.0 -0.06 -0.6582 -0.7509 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C09 compound treatment 415993.0 -81900.0 -0.49 513719.0 46600.0 0.26 -0.1576 -0.284 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C10 compound treatment 179601.0 -318000.0 -1.89 68875.0 -398000.0 -2.26 -2.9412 -0.9961 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C11 mock treatment 402926.0 -95000.0 -0.57 299599.0 -168000.0 -0.95 -1.0736 -0.9689 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C12 mock treatment 464503.0 -33400.0 -0.2 317450.0 -150000.0 -0.85 -0.7427 -0.8494 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C13 compound treatment 480386.0 -17500.0 -0.1 487801.0 20600.0 0.12 0.0092 0.0584 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C14 compound treatment 330459.0 -167000.0 -1.0 323075.0 -144000.0 -0.82 -1.2841 -0.9953 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C15 mock treatment 423734.0 -74200.0 -0.44 474553.0 7390.0 0.04 -0.2825 -0.6369 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C16 mock treatment 421841.0 -76100.0 -0.45 489933.0 22800.0 0.13 -0.2286 -0.4854 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C17 compound treatment 440447.0 -57500.0 -0.34 398136.0 -69000.0 -0.39 -0.5195 -0.9977 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C18 compound treatment 404573.0 -93400.0 -0.56 205399.0 -262000.0 -1.49 -1.4454 -0.9097 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C19 compound treatment 449086.0 -48800.0 -0.29 464307.0 -2850.0 -0.02 -0.217 -0.7454 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C20 compound treatment 105146.0 -393000.0 -2.34 253504.0 -214000.0 -1.22 -2.5121 -0.9535 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C21 compound treatment 367544.0 -130000.0 -0.78 516600.0 49400.0 0.28 -0.3499 -0.4239 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C22 compound treatment 397048.0 -101000.0 -0.6 430903.0 -36300.0 -0.21 -0.5703 -0.8984 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C23 compound treatment 690528.0 193000.0 1.15 221722.0 -245000.0 -1.4 -0.1764 -0.0977 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 C24 compound treatment 689076.0 191000.0 1.14 593390.0 126000.0 0.72 1.312 0.9754 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D01 compound treatment 237080.0 -261000.0 -1.55 280375.0 -187000.0 -1.06 -1.8488 -0.9829 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D02 compound treatment 311162.0 -187000.0 -1.11 331082.0 -136000.0 -0.77 -1.3332 -0.9843 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D03 compound treatment 59992.0 -438000.0 -2.61 63081.0 -404000.0 -2.3 -3.4678 -0.998 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D04 compound treatment 313063.0 -185000.0 -1.1 370405.0 -96800.0 -0.55 -1.167 -0.9487 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D05 compound treatment 187793.0 -310000.0 -1.85 209781.0 -257000.0 -1.46 -2.3401 -0.9934 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D06 compound treatment 292198.0 -206000.0 -1.22 323416.0 -144000.0 -0.82 -1.4438 -0.9807 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D07 compound treatment 63602.0 -434000.0 -2.58 74692.0 -392000.0 -2.23 -3.4059 -0.9973 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D08 compound treatment 333793.0 -164000.0 -0.98 379013.0 -88100.0 -0.5 -1.0452 -0.9519 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D09 compound treatment 202570.0 -295000.0 -1.76 271752.0 -195000.0 -1.11 -2.0287 -0.9755 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D10 compound treatment 191424.0 -307000.0 -1.82 78422.0 -389000.0 -2.21 -2.853 -0.9954 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D11 mock treatment 454614.0 -43300.0 -0.26 214528.0 -253000.0 -1.44 -1.1981 -0.8209 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D12 mock treatment 554772.0 56800.0 0.34 524764.0 57600.0 0.33 0.4708 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D13 compound treatment 229571.0 -268000.0 -1.6 244639.0 -223000.0 -1.27 -2.0241 -0.9934 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D14 compound treatment 190815.0 -307000.0 -1.83 225230.0 -242000.0 -1.38 -2.2653 -0.9902 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D15 mock treatment 492182.0 -5750.0 -0.03 279178.0 -188000.0 -1.07 -0.7801 -0.7294 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D16 mock treatment 504933.0 7010.0 0.04 457500.0 -9660.0 -0.05 -0.0094 -0.1358 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D17 compound treatment 79163.0 -419000.0 -2.49 78501.0 -389000.0 -2.21 -3.3251 -0.9982 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D18 compound treatment 314184.0 -184000.0 -1.09 267917.0 -199000.0 -1.13 -1.5744 -0.9998 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D19 compound treatment 144718.0 -353000.0 -2.1 105327.0 -362000.0 -2.06 -2.9414 -0.9999 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D20 compound treatment 299922.0 -198000.0 -1.18 420586.0 -46600.0 -0.26 -1.0205 -0.845 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D21 compound treatment 70703.0 -427000.0 -2.54 69191.0 -398000.0 -2.26 -3.3982 -0.9983 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D22 compound treatment 416182.0 -81700.0 -0.49 356439.0 -111000.0 -0.63 -0.7892 -0.9919 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D23 compound treatment 355325.0 -143000.0 -0.85 144450.0 -323000.0 -1.84 -1.8978 -0.9386 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 D24 compound treatment 55325.0 -443000.0 -2.63 57415.0 -410000.0 -2.33 -3.5102 -0.9981 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E01 mock treatment 494100.0 -3830.0 -0.02 495701.0 28500.0 0.16 0.0987 0.602 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E02 mock treatment 246309.0 -252000.0 -1.5 186103.0 -281000.0 -1.6 -2.1891 -0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E03 compound treatment 353610.0 -144000.0 -0.86 461758.0 -5400.0 -0.03 -0.6291 -0.7319 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E04 compound treatment 203236.0 -295000.0 -1.75 47596.0 -420000.0 -2.39 -2.9273 -0.9885 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E05 compound treatment 442255.0 -55700.0 -0.33 273185.0 -194000.0 -1.1 -1.0143 -0.8806 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E06 compound treatment 185090.0 -313000.0 -1.86 283561.0 -184000.0 -1.04 -2.0548 -0.9626 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E07 compound treatment 231510.0 -266000.0 -1.59 228373.0 -239000.0 -1.36 -2.0814 -0.997 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E08 compound treatment 402531.0 -95400.0 -0.57 400523.0 -66600.0 -0.38 -0.6694 -0.9807 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E09 mock treatment 415593.0 -82300.0 -0.49 180165.0 -287000.0 -1.63 -1.5005 -0.8806 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E10 mock treatment 453681.0 -44200.0 -0.26 406854.0 -60300.0 -0.34 -0.4287 -0.9915 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E11 compound treatment 164110.0 -334000.0 -1.99 220260.0 -247000.0 -1.4 -2.3976 -0.9856 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E12 compound treatment 424046.0 -73900.0 -0.44 483866.0 16700.0 0.09 -0.2437 -0.5418 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E13 compound treatment 335600.0 -162000.0 -0.97 379496.0 -87700.0 -0.5 -1.0356 -0.9526 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E14 compound treatment 352524.0 -145000.0 -0.87 147121.0 -320000.0 -1.82 -1.8988 -0.9422 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E15 compound treatment 560919.0 63000.0 0.37 568392.0 101000.0 0.58 0.6722 0.9784 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E16 compound treatment 370338.0 -128000.0 -0.76 362907.0 -104000.0 -0.59 -0.9562 -0.9925 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E17 mock treatment 460196.0 -37700.0 -0.22 254795.0 -212000.0 -1.21 -1.0127 -0.8245 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E18 mock treatment 423755.0 -74200.0 -0.44 261851.0 -205000.0 -1.17 -1.1377 -0.9115 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E19 compound treatment 476488.0 -21400.0 -0.13 538174.0 71000.0 0.4 0.1953 0.4612 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E20 compound treatment 275652.0 -222000.0 -1.32 61467.0 -406000.0 -2.31 -2.5668 -0.9652 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E21 compound treatment 112052.0 -386000.0 -2.3 86317.0 -381000.0 -2.17 -3.1553 -0.9996 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E22 compound treatment 384390.0 -114000.0 -0.68 314435.0 -153000.0 -0.87 -1.0919 -0.9923 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E23 compound treatment 486958.0 -11000.0 -0.07 471819.0 4660.0 0.03 -0.0274 -0.3894 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 E24 compound treatment 261450.0 -236000.0 -1.41 299569.0 -168000.0 -0.95 -1.6691 -0.982 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F01 mock treatment 555004.0 57100.0 0.34 556144.0 89000.0 0.51 0.598 0.9812 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F02 mock treatment 467623.0 -30300.0 -0.18 700366.0 233000.0 1.33 0.8102 0.6054 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F03 compound treatment 278194.0 -220000.0 -1.31 457285.0 -9880.0 -0.06 -0.9644 -0.7368 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F04 compound treatment 61672.0 -436000.0 -2.6 63034.0 -404000.0 -2.3 -3.4609 -0.9981 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F05 compound treatment 251351.0 -247000.0 -1.47 279220.0 -188000.0 -1.07 -1.7934 -0.9879 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F06 compound treatment 67861.0 -430000.0 -2.56 60988.0 -406000.0 -2.31 -3.4431 -0.9987 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F07 compound treatment 73020.0 -425000.0 -2.53 85578.0 -382000.0 -2.17 -3.3225 -0.9971 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F08 compound treatment 116695.0 -381000.0 -2.27 150737.0 -316000.0 -1.8 -2.8767 -0.9934 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F09 mock treatment 495917.0 -2010.0 -0.01 551784.0 84600.0 0.48 0.3318 0.6893 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F10 mock treatment 472924.0 -25000.0 -0.15 301529.0 -166000.0 -0.94 -0.7713 -0.8088 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F11 compound treatment 400811.0 -97100.0 -0.58 371619.0 -95500.0 -0.54 -0.7929 -0.9995 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F12 compound treatment 244548.0 -253000.0 -1.51 276107.0 -191000.0 -1.09 -1.8345 -0.9871 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F13 compound treatment 134357.0 -364000.0 -2.16 124665.0 -342000.0 -1.95 -2.9072 -0.9986 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F14 compound treatment 54830.0 -443000.0 -2.64 55041.0 -412000.0 -2.34 -3.5219 -0.9983 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F15 compound treatment 53979.0 -444000.0 -2.64 49523.0 -418000.0 -2.38 -3.5476 -0.9986 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F16 compound treatment 115952.0 -382000.0 -2.27 99754.0 -367000.0 -2.09 -3.0849 -0.9991 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F17 mock treatment 506615.0 8690.0 0.05 475651.0 8490.0 0.05 0.0707 0.9994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F18 mock treatment 568528.0 70600.0 0.42 547881.0 80700.0 0.46 0.6217 0.999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F19 compound treatment 94536.0 -403000.0 -2.4 54353.0 -413000.0 -2.35 -3.3575 -0.9999 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F20 compound treatment 71320.0 -427000.0 -2.54 84233.0 -383000.0 -2.18 -3.3351 -0.9971 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F21 compound treatment 49730.0 -448000.0 -2.67 33100.0 -434000.0 -2.47 -3.6316 -0.9993 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F22 compound treatment 388342.0 -110000.0 -0.65 232833.0 -234000.0 -1.33 -1.4034 -0.946 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F23 compound treatment 108229.0 -390000.0 -2.32 98642.0 -369000.0 -2.1 -3.1218 -0.9987 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 F24 compound treatment 58819.0 -439000.0 -2.61 84024.0 -383000.0 -2.18 -3.3885 -0.9959 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G01 compound treatment 353975.0 -144000.0 -0.86 262546.0 -205000.0 -1.16 -1.4286 -0.9887 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G02 compound treatment 172398.0 -326000.0 -1.94 453136.0 -14000.0 -0.08 -1.4263 -0.7356 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G03 mock treatment 459440.0 -38500.0 -0.23 461461.0 -5700.0 -0.03 -0.1849 -0.7992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G04 mock treatment 443715.0 -54200.0 -0.32 267278.0 -200000.0 -1.14 -1.0319 -0.8733 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G05 compound treatment 372454.0 -125000.0 -0.75 502133.0 35000.0 0.2 -0.3874 -0.5013 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G06 compound treatment 454154.0 -43800.0 -0.26 493241.0 26100.0 0.15 -0.0793 -0.2647 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G07 compound treatment 496619.0 -1310.0 -0.01 193489.0 -274000.0 -1.56 -1.106 -0.7106 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G08 compound treatment 315566.0 -182000.0 -1.09 186493.0 -281000.0 -1.6 -1.896 -0.9823 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G09 compound treatment 196001.0 -302000.0 -1.8 88532.0 -379000.0 -2.15 -2.7931 -0.996 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G10 compound treatment 453030.0 -44900.0 -0.27 263768.0 -203000.0 -1.16 -1.0068 -0.8481 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G11 compound treatment 346932.0 -151000.0 -0.9 162984.0 -304000.0 -1.73 -1.8586 -0.9535 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G12 compound treatment 434495.0 -63400.0 -0.38 441472.0 -25700.0 -0.15 -0.3702 -0.9146 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G13 compound treatment 475734.0 -22200.0 -0.13 528264.0 61100.0 0.35 0.1523 0.4097 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G14 compound treatment 316427.0 -182000.0 -1.08 410919.0 -56200.0 -0.32 -0.99 -0.8788 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G15 compound treatment 476649.0 -21300.0 -0.13 284101.0 -183000.0 -1.04 -0.8257 -0.7873 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G16 compound treatment 170220.0 -328000.0 -1.95 212332.0 -255000.0 -1.45 -2.4038 -0.9893 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G17 compound treatment 493911.0 -4020.0 -0.02 288347.0 -179000.0 -1.02 -0.7359 -0.7235 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G18 compound treatment 137025.0 -361000.0 -2.15 99718.0 -367000.0 -2.09 -2.9963 -0.9999 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G19 mock treatment 496259.0 -1670.0 -0.01 193252.0 -274000.0 -1.56 -1.1084 -0.7116 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G20 mock treatment 495999.0 -1930.0 -0.01 156815.0 -310000.0 -1.76 -1.2561 -0.7117 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G21 compound treatment 228158.0 -270000.0 -1.61 165305.0 -302000.0 -1.72 -2.3491 -0.9994 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G22 compound treatment 434764.0 -63200.0 -0.38 232757.0 -234000.0 -1.33 -1.2084 -0.8725 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G23 compound treatment 539972.0 42000.0 0.25 132364.0 -335000.0 -1.9 -1.1693 -0.6089 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 G24 compound treatment 566729.0 68800.0 0.41 547741.0 80600.0 0.46 0.6136 0.9984 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H01 compound treatment 348982.0 -149000.0 -0.89 310571.0 -157000.0 -0.89 -1.2565 -1.0 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H02 compound treatment 360916.0 -137000.0 -0.82 159949.0 -307000.0 -1.75 -1.8119 -0.9398 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H03 mock treatment 480939.0 -17000.0 -0.1 503170.0 36000.0 0.2 0.0733 0.321 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H04 mock treatment 477703.0 -20200.0 -0.12 508328.0 41200.0 0.23 0.0804 0.3055 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H05 compound treatment 245692.0 -252000.0 -1.5 285164.0 -182000.0 -1.03 -1.7933 -0.9835 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H06 compound treatment 63372.0 -435000.0 -2.59 60540.0 -407000.0 -2.31 -3.4638 -0.9984 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H07 compound treatment 199974.0 -298000.0 -1.77 104554.0 -363000.0 -2.06 -2.712 -0.9972 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H08 compound treatment 79371.0 -419000.0 -2.49 53384.0 -414000.0 -2.35 -3.4253 -0.9996 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H09 compound treatment 244488.0 -253000.0 -1.51 303786.0 -163000.0 -0.93 -1.7235 -0.9729 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H10 compound treatment 235434.0 -262000.0 -1.56 70577.0 -397000.0 -2.26 -2.6994 -0.9839 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H11 compound treatment 301181.0 -197000.0 -1.17 391515.0 -75600.0 -0.43 -1.1321 -0.9076 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H12 compound treatment 157138.0 -341000.0 -2.03 71560.0 -396000.0 -2.25 -3.0249 -0.9987 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H13 compound treatment 117381.0 -381000.0 -2.26 130220.0 -337000.0 -1.92 -2.9563 -0.9965 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H14 compound treatment 198197.0 -300000.0 -1.78 104525.0 -363000.0 -2.06 -2.7196 -0.9974 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H15 compound treatment 395514.0 -102000.0 -0.61 211196.0 -256000.0 -1.46 -1.4603 -0.9253 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H16 compound treatment 250395.0 -248000.0 -1.47 97169.0 -370000.0 -2.1 -2.5295 -0.9848 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H17 compound treatment 498757.0 829.0 0.0 338067.0 -129000.0 -0.73 -0.5156 -0.7023 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H18 compound treatment 249489.0 -248000.0 -1.48 230902.0 -236000.0 -1.34 -1.9955 -0.9989 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H19 mock treatment 453982.0 -43900.0 -0.26 490517.0 23400.0 0.13 -0.091 -0.3103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H20 mock treatment 526172.0 28200.0 0.17 292587.0 -175000.0 -0.99 -0.5831 -0.5791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H21 compound treatment 236908.0 -261000.0 -1.55 58957.0 -408000.0 -2.32 -2.7399 -0.9809 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H22 compound treatment 60022.0 -438000.0 -2.61 45402.0 -422000.0 -2.4 -3.5388 -0.9991 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H23 compound treatment 194218.0 -304000.0 -1.81 178048.0 -289000.0 -1.64 -2.4407 -0.9989 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 H24 compound treatment 345897.0 -152000.0 -0.9 249923.0 -217000.0 -1.24 -1.5133 -0.9883 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I01 compound treatment 434872.0 -63100.0 -0.38 418918.0 -48200.0 -0.27 -0.4593 -0.9881 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I02 compound treatment 466709.0 -31200.0 -0.19 384403.0 -82800.0 -0.47 -0.4642 -0.9174 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I03 compound treatment 215910.0 -282000.0 -1.68 305269.0 -162000.0 -0.92 -1.8378 -0.96 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I04 compound treatment 88289.0 -410000.0 -2.44 211295.0 -256000.0 -1.46 -2.7528 -0.9696 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I05 mock treatment 302267.0 -196000.0 -1.16 238658.0 -229000.0 -1.3 -1.7422 -0.9985 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I06 mock treatment 436553.0 -61400.0 -0.37 411601.0 -55600.0 -0.32 -0.4817 -0.9974 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I07 compound treatment 390434.0 -107000.0 -0.64 353600.0 -114000.0 -0.65 -0.909 -1.0 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I08 compound treatment 498041.0 113.0 0.0 350874.0 -116000.0 -0.66 -0.4671 -0.7064 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I09 compound treatment 521201.0 23300.0 0.14 523784.0 56600.0 0.32 0.3256 0.929 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I10 compound treatment 211759.0 -286000.0 -1.7 164571.0 -303000.0 -1.72 -2.421 -1.0 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I11 compound treatment 395407.0 -103000.0 -0.61 224525.0 -243000.0 -1.38 -1.4071 -0.9327 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I12 compound treatment 60217.0 -438000.0 -2.6 62357.0 -405000.0 -2.3 -3.4698 -0.9981 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I13 compound treatment 54890.0 -443000.0 -2.64 56068.0 -411000.0 -2.34 -3.5175 -0.9982 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I14 compound treatment 394947.0 -103000.0 -0.61 521383.0 54200.0 0.31 -0.2153 -0.3139 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I15 compound treatment 69878.0 -428000.0 -2.55 115549.0 -352000.0 -2.0 -3.2152 -0.9928 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I16 compound treatment 193899.0 -304000.0 -1.81 59022.0 -408000.0 -2.32 -2.9206 -0.9924 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I17 compound treatment 202481.0 -295000.0 -1.76 86190.0 -381000.0 -2.17 -2.7753 -0.9946 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I18 compound treatment 49292.0 -449000.0 -2.67 190004.0 -277000.0 -1.58 -3.0025 -0.9684 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I19 compound treatment 540745.0 42800.0 0.25 518701.0 51500.0 0.29 0.3874 0.9976 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I20 compound treatment 128298.0 -370000.0 -2.2 80167.0 -387000.0 -2.2 -3.1117 -1.0 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I21 mock treatment 513897.0 16000.0 0.1 306739.0 -160000.0 -0.91 -0.5779 -0.63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I22 mock treatment 440483.0 -57400.0 -0.34 537649.0 70500.0 0.4 0.0417 0.0791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I23 compound treatment 581701.0 83800.0 0.5 580951.0 114000.0 0.65 0.8101 0.9917 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 I24 compound treatment 129158.0 -369000.0 -2.19 145503.0 -322000.0 -1.83 -2.8453 -0.9959 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J01 compound treatment 483495.0 -14400.0 -0.09 327035.0 -140000.0 -0.8 -0.6242 -0.7788 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J02 compound treatment 243126.0 -255000.0 -1.52 133036.0 -334000.0 -1.9 -2.4158 -0.9938 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J03 compound treatment 336796.0 -161000.0 -0.96 121043.0 -346000.0 -1.97 -2.0699 -0.9454 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J04 compound treatment 300131.0 -198000.0 -1.18 302679.0 -164000.0 -0.94 -1.4938 -0.9935 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J05 mock treatment 516756.0 18800.0 0.11 193810.0 -273000.0 -1.55 -1.0199 -0.6544 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J06 mock treatment 505788.0 7860.0 0.05 356603.0 -111000.0 -0.63 -0.4115 -0.6527 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J07 compound treatment 79552.0 -418000.0 -2.49 214901.0 -252000.0 -1.43 -2.775 -0.9657 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J08 compound treatment 396919.0 -101000.0 -0.6 395343.0 -71800.0 -0.41 -0.7139 -0.9823 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J09 compound treatment 64723.0 -433000.0 -2.58 39862.0 -427000.0 -2.43 -3.5413 -0.9996 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J10 compound treatment 334124.0 -164000.0 -0.97 394332.0 -72800.0 -0.41 -0.9822 -0.9273 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J11 compound treatment 345931.0 -152000.0 -0.9 227820.0 -239000.0 -1.36 -1.6021 -0.9803 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J12 compound treatment 78989.0 -419000.0 -2.49 54734.0 -412000.0 -2.35 -3.4214 -0.9995 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J13 compound treatment 419587.0 -78300.0 -0.47 132815.0 -334000.0 -1.9 -1.6741 -0.8552 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J14 compound treatment 285998.0 -212000.0 -1.26 286420.0 -181000.0 -1.03 -1.6186 -0.9948 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J15 compound treatment 116902.0 -381000.0 -2.27 43466.0 -424000.0 -2.41 -3.3072 -0.9995 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J16 compound treatment 304834.0 -193000.0 -1.15 199543.0 -268000.0 -1.52 -1.8887 -0.9904 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J17 compound treatment 357285.0 -141000.0 -0.84 108038.0 -359000.0 -2.04 -2.0359 -0.9224 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J18 compound treatment 285020.0 -213000.0 -1.27 320229.0 -147000.0 -0.84 -1.4868 -0.9796 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J19 compound treatment 54362.0 -444000.0 -2.64 57302.0 -410000.0 -2.33 -3.5148 -0.9981 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J20 compound treatment 254663.0 -243000.0 -1.45 171007.0 -296000.0 -1.68 -2.2146 -0.9972 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J21 mock treatment 549396.0 51500.0 0.31 472679.0 5520.0 0.03 0.2388 0.7755 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J22 mock treatment 578043.0 80100.0 0.48 527230.0 60100.0 0.34 0.5787 0.9866 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J23 compound treatment 179240.0 -319000.0 -1.9 566281.0 99100.0 0.56 -0.9426 -0.4764 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 J24 compound treatment 344638.0 -153000.0 -0.91 357099.0 -110000.0 -0.63 -1.0877 -0.9831 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K01 compound treatment 136915.0 -361000.0 -2.15 192656.0 -275000.0 -1.56 -2.6231 -0.9877 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K02 compound treatment 351033.0 -147000.0 -0.87 345342.0 -122000.0 -0.69 -1.108 -0.9934 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K03 compound treatment 406638.0 -91300.0 -0.54 382210.0 -85000.0 -0.48 -0.7258 -0.9983 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K04 compound treatment 526945.0 29000.0 0.17 406043.0 -61100.0 -0.35 -0.1237 -0.3186 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K05 compound treatment 475029.0 -22900.0 -0.14 326569.0 -141000.0 -0.8 -0.6617 -0.8159 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K06 compound treatment 506947.0 9020.0 0.05 508800.0 41600.0 0.24 0.2054 0.8459 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K07 mock treatment 476177.0 -21800.0 -0.13 247868.0 -219000.0 -1.25 -0.9733 -0.7763 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K08 mock treatment 410953.0 -87000.0 -0.52 598756.0 132000.0 0.75 0.1631 0.1793 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K09 compound treatment 369214.0 -129000.0 -0.77 441558.0 -25600.0 -0.15 -0.6446 -0.8267 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K10 compound treatment 446975.0 -51000.0 -0.3 465744.0 -1420.0 -0.01 -0.2201 -0.7256 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K11 compound treatment 283263.0 -215000.0 -1.28 346607.0 -121000.0 -0.69 -1.3881 -0.9574 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K12 compound treatment 440160.0 -57800.0 -0.34 504175.0 37000.0 0.21 -0.0943 -0.2338 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K13 compound treatment 443249.0 -54700.0 -0.33 107817.0 -359000.0 -2.04 -1.6751 -0.8095 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K14 compound treatment 51627.0 -446000.0 -2.66 92833.0 -374000.0 -2.13 -3.3834 -0.994 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K15 mock treatment 472688.0 -25200.0 -0.15 519221.0 52100.0 0.3 0.1031 0.3106 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K16 mock treatment 481278.0 -16600.0 -0.1 480486.0 13300.0 0.08 -0.0165 -0.1322 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K17 compound treatment 305249.0 -193000.0 -1.15 376931.0 -90200.0 -0.51 -1.1737 -0.9342 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K18 compound treatment 112190.0 -386000.0 -2.3 129556.0 -338000.0 -1.92 -2.9809 -0.996 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K19 compound treatment 389360.0 -109000.0 -0.65 462930.0 -4230.0 -0.02 -0.4739 -0.7329 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K20 compound treatment 205094.0 -293000.0 -1.74 265749.0 -201000.0 -1.15 -2.0422 -0.9793 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K21 compound treatment 274598.0 -223000.0 -1.33 378268.0 -88900.0 -0.51 -1.2973 -0.9123 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K22 compound treatment 309989.0 -188000.0 -1.12 435425.0 -31700.0 -0.18 -0.9185 -0.8107 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K23 mock treatment 553134.0 55200.0 0.33 529461.0 62300.0 0.35 0.4828 0.9993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 K24 mock treatment 601905.0 104000.0 0.62 518378.0 51200.0 0.29 0.6435 0.9409 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L01 compound treatment 540709.0 42800.0 0.25 543407.0 76200.0 0.43 0.4866 0.9678 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L02 compound treatment 294667.0 -203000.0 -1.21 277776.0 -189000.0 -1.08 -1.6169 -0.9983 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L03 compound treatment 567272.0 69300.0 0.41 493766.0 26600.0 0.15 0.3988 0.9073 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L04 compound treatment 187359.0 -311000.0 -1.85 225844.0 -241000.0 -1.37 -2.2773 -0.9893 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L05 compound treatment 539498.0 41600.0 0.25 565073.0 97900.0 0.56 0.5687 0.9333 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L06 compound treatment 277074.0 -221000.0 -1.31 390822.0 -76300.0 -0.43 -1.2364 -0.8932 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L07 mock treatment 588568.0 90600.0 0.54 541776.0 74600.0 0.42 0.6815 0.9929 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L08 mock treatment 341299.0 -157000.0 -0.93 534575.0 67400.0 0.38 -0.3881 -0.385 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L09 compound treatment 542249.0 44300.0 0.26 548041.0 80900.0 0.46 0.5117 0.9652 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L10 compound treatment 431768.0 -66200.0 -0.39 268656.0 -199000.0 -1.13 -1.0766 -0.9005 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L11 compound treatment 557006.0 59100.0 0.35 475005.0 7840.0 0.04 0.2802 0.7905 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L12 compound treatment 413860.0 -84100.0 -0.5 452419.0 -14700.0 -0.08 -0.4131 -0.8142 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L13 compound treatment 664216.0 166000.0 0.99 595312.0 128000.0 0.73 1.2151 0.9887 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L14 compound treatment 383850.0 -114000.0 -0.68 429374.0 -37800.0 -0.21 -0.632 -0.8875 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L15 mock treatment 555393.0 57500.0 0.34 532979.0 65800.0 0.37 0.5065 0.999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L16 mock treatment 594227.0 96300.0 0.57 519187.0 52000.0 0.3 0.6145 0.9527 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L17 compound treatment 186939.0 -311000.0 -1.85 199378.0 -268000.0 -1.52 -2.3855 -0.9953 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L18 compound treatment 436451.0 -61500.0 -0.37 376220.0 -90900.0 -0.52 -0.6244 -0.9856 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L19 compound treatment 601371.0 103000.0 0.62 522982.0 55800.0 0.32 0.6598 0.9525 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L20 compound treatment 418475.0 -79500.0 -0.47 337115.0 -130000.0 -0.74 -0.8573 -0.9767 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L21 compound treatment 508032.0 10100.0 0.06 531521.0 64400.0 0.37 0.3013 0.8124 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L22 compound treatment 404215.0 -93700.0 -0.56 455055.0 -12100.0 -0.07 -0.443 -0.7884 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L23 mock treatment 577403.0 79500.0 0.47 408183.0 -59000.0 -0.34 0.0973 0.1678 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 L24 mock treatment 588761.0 90800.0 0.54 583452.0 116000.0 0.66 0.8499 0.995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M01 compound treatment 248097.0 -250000.0 -1.49 216590.0 -251000.0 -1.42 -2.0589 -0.9998 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M02 compound treatment 444375.0 -53600.0 -0.32 259267.0 -208000.0 -1.18 -1.0613 -0.8668 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M03 compound treatment 304751.0 -193000.0 -1.15 110582.0 -357000.0 -2.03 -2.2468 -0.9639 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M04 compound treatment 493916.0 -4010.0 -0.02 319743.0 -147000.0 -0.84 -0.6097 -0.7269 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M05 compound treatment 569068.0 71100.0 0.42 654649.0 187000.0 1.07 1.0533 0.9182 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M06 compound treatment 497830.0 -97.6 0.0 562016.0 94900.0 0.54 0.381 0.7063 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M07 compound treatment 111428.0 -386000.0 -2.3 76673.0 -390000.0 -2.22 -3.1967 -0.9998 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M08 compound treatment 106378.0 -392000.0 -2.33 135762.0 -331000.0 -1.88 -2.9804 -0.9945 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M09 mock treatment 532818.0 34900.0 0.21 544697.0 77500.0 0.44 0.4586 0.941 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M10 mock treatment 255038.0 -243000.0 -1.45 229201.0 -238000.0 -1.35 -1.979 -0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M11 compound treatment 88334.0 -410000.0 -2.44 122799.0 -344000.0 -1.96 -3.1084 -0.9941 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M12 compound treatment 563369.0 65400.0 0.39 392299.0 -74900.0 -0.43 -0.0256 -0.0444 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M13 mock treatment 465792.0 -32100.0 -0.19 587765.0 121000.0 0.69 0.3497 0.4912 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M14 mock treatment 489484.0 -8440.0 -0.05 595269.0 128000.0 0.73 0.4796 0.6568 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M15 compound treatment 52933.0 -445000.0 -2.65 42927.0 -424000.0 -2.41 -3.5786 -0.9989 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M16 compound treatment 73687.0 -424000.0 -2.52 187986.0 -279000.0 -1.59 -2.9079 -0.975 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M17 compound treatment 382801.0 -115000.0 -0.69 372849.0 -94300.0 -0.54 -0.8637 -0.9927 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M18 compound treatment 331368.0 -167000.0 -0.99 330508.0 -137000.0 -0.78 -1.2504 -0.9927 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M19 compound treatment 346116.0 -152000.0 -0.9 176578.0 -291000.0 -1.65 -1.8073 -0.9596 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M20 compound treatment 366118.0 -132000.0 -0.78 397446.0 -69700.0 -0.4 -0.835 -0.95 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M21 compound treatment 461588.0 -36300.0 -0.22 343435.0 -124000.0 -0.7 -0.6504 -0.8837 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M22 compound treatment 391323.0 -107000.0 -0.63 428430.0 -38700.0 -0.22 -0.6044 -0.8999 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M23 compound treatment 408503.0 -89400.0 -0.53 473787.0 6630.0 0.04 -0.3497 -0.6554 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 M24 compound treatment 49799.0 -448000.0 -2.67 79087.0 -388000.0 -2.21 -3.4464 -0.9956 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N01 compound treatment 554940.0 57000.0 0.34 639215.0 172000.0 0.98 0.9318 0.8998 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N02 compound treatment 359929.0 -138000.0 -0.82 424365.0 -42800.0 -0.24 -0.7528 -0.8789 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N03 compound treatment 598191.0 100000.0 0.6 421124.0 -46000.0 -0.26 0.2368 0.3634 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N04 compound treatment 501968.0 4040.0 0.02 534805.0 67600.0 0.38 0.289 0.7498 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N05 compound treatment 577332.0 79400.0 0.47 611752.0 145000.0 0.82 0.9156 0.9654 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N06 compound treatment 586755.0 88800.0 0.53 618370.0 151000.0 0.86 0.9818 0.9727 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N07 compound treatment 565158.0 67200.0 0.4 560239.0 93100.0 0.53 0.6572 0.9905 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N08 compound treatment 504547.0 6620.0 0.04 549808.0 82600.0 0.47 0.3602 0.7637 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N09 mock treatment 618059.0 120000.0 0.71 622833.0 156000.0 0.89 1.1315 0.9944 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N10 mock treatment 611737.0 114000.0 0.68 606993.0 140000.0 0.8 1.0412 0.9968 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N11 compound treatment 577790.0 79900.0 0.48 599115.0 132000.0 0.75 0.8667 0.9757 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N12 compound treatment 395914.0 -102000.0 -0.61 438724.0 -28400.0 -0.16 -0.5437 -0.8653 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N13 mock treatment 556010.0 58100.0 0.35 549831.0 82700.0 0.47 0.5769 0.9886 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N14 mock treatment 523180.0 25300.0 0.15 542585.0 75400.0 0.43 0.4096 0.9012 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N15 compound treatment 207537.0 -290000.0 -1.73 253678.0 -213000.0 -1.21 -2.0805 -0.9851 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N16 compound treatment 436039.0 -61900.0 -0.37 419543.0 -47600.0 -0.27 -0.4519 -0.9886 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N17 compound treatment 573095.0 75200.0 0.45 552871.0 85700.0 0.49 0.661 0.9991 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N18 compound treatment 413373.0 -84600.0 -0.5 384153.0 -83000.0 -0.47 -0.6896 -0.9995 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N19 compound treatment 458288.0 -39600.0 -0.24 426987.0 -40200.0 -0.23 -0.3284 -0.9999 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N20 compound treatment 370246.0 -128000.0 -0.76 249820.0 -217000.0 -1.24 -1.4113 -0.9727 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N21 compound treatment 477420.0 -20500.0 -0.12 454212.0 -12900.0 -0.07 -0.1384 -0.9707 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N22 compound treatment 278314.0 -220000.0 -1.31 256423.0 -211000.0 -1.2 -1.7716 -0.9991 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N23 compound treatment 661260.0 163000.0 0.97 620428.0 153000.0 0.87 1.3037 0.9985 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 N24 compound treatment 499064.0 1140.0 0.01 463573.0 -3590.0 -0.02 -0.0096 -0.4487 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O01 compound treatment 349015.0 -149000.0 -0.89 363850.0 -103000.0 -0.59 -1.0421 -0.9801 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O02 compound treatment 459326.0 -38600.0 -0.23 486432.0 19300.0 0.11 -0.085 -0.3338 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O03 compound treatment 522346.0 24400.0 0.15 522800.0 55600.0 0.32 0.3265 0.9377 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O04 compound treatment 564475.0 66500.0 0.4 626390.0 159000.0 0.91 0.9203 0.9312 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O05 compound treatment 174155.0 -324000.0 -1.93 162742.0 -304000.0 -1.73 -2.5866 -0.9986 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O06 compound treatment 401023.0 -96900.0 -0.58 504678.0 37500.0 0.21 -0.2569 -0.4178 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O07 compound treatment 322478.0 -175000.0 -1.04 396793.0 -70400.0 -0.4 -1.0213 -0.9133 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O08 compound treatment 442404.0 -55500.0 -0.33 221792.0 -245000.0 -1.4 -1.2203 -0.851 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O09 compound treatment 520158.0 22200.0 0.13 146247.0 -321000.0 -1.82 -1.1969 -0.6541 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O10 compound treatment 108052.0 -390000.0 -2.32 55752.0 -411000.0 -2.34 -3.295 -1.0 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O11 mock treatment 499539.0 1610.0 0.01 469485.0 2320.0 0.01 0.0161 0.9876 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O12 mock treatment 543860.0 45900.0 0.27 612774.0 146000.0 0.83 0.7788 0.8931 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O13 compound treatment 673528.0 176000.0 1.05 626355.0 159000.0 0.91 1.3791 0.9974 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O14 compound treatment 530204.0 32300.0 0.19 218889.0 -248000.0 -1.41 -0.8625 -0.6053 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O15 compound treatment 663976.0 166000.0 0.99 656009.0 189000.0 1.07 1.4582 0.9991 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O16 compound treatment 472586.0 -25300.0 -0.15 475571.0 8410.0 0.05 -0.0728 -0.4603 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O17 compound treatment 401622.0 -96300.0 -0.57 471094.0 3930.0 0.02 -0.3895 -0.679 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O18 compound treatment 357037.0 -141000.0 -0.84 136121.0 -331000.0 -1.88 -1.9241 -0.9336 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O19 compound treatment 559115.0 61200.0 0.36 535841.0 68700.0 0.39 0.5337 0.9994 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O20 compound treatment 52490.0 -445000.0 -2.65 53942.0 -413000.0 -2.35 -3.5361 -0.9982 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O21 compound treatment 408030.0 -89900.0 -0.54 475358.0 8200.0 0.05 -0.3454 -0.6431 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O22 compound treatment 312715.0 -185000.0 -1.1 327865.0 -139000.0 -0.79 -1.3396 -0.9869 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O23 compound treatment 224087.0 -274000.0 -1.63 162345.0 -305000.0 -1.73 -2.3781 -0.9995 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 O24 compound treatment 117988.0 -380000.0 -2.26 136063.0 -331000.0 -1.88 -2.9303 -0.9959 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P01 compound treatment 403268.0 -94700.0 -0.56 434262.0 -32900.0 -0.19 -0.5306 -0.8939 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P02 compound treatment 428719.0 -69200.0 -0.41 442801.0 -24400.0 -0.14 -0.3892 -0.8956 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P03 compound treatment 648107.0 150000.0 0.89 656756.0 190000.0 1.08 1.3944 0.9957 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P04 compound treatment 416505.0 -81400.0 -0.48 479184.0 12000.0 0.07 -0.2943 -0.6014 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P05 compound treatment 507741.0 9810.0 0.06 604510.0 137000.0 0.78 0.5936 0.7579 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P06 compound treatment 336814.0 -161000.0 -0.96 331879.0 -135000.0 -0.77 -1.222 -0.994 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P07 compound treatment 574476.0 76500.0 0.46 562011.0 94800.0 0.54 0.7035 0.9965 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P08 compound treatment 324995.0 -173000.0 -1.03 116508.0 -351000.0 -1.99 -2.1378 -0.9527 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P09 compound treatment 93854.0 -404000.0 -2.4 87430.0 -380000.0 -2.16 -3.2274 -0.9986 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P10 compound treatment 341807.0 -156000.0 -0.93 414966.0 -52200.0 -0.3 -0.8669 -0.8887 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P11 mock treatment 638062.0 140000.0 0.83 704004.0 237000.0 1.35 1.5421 0.9734 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P12 mock treatment 691979.0 194000.0 1.15 674380.0 207000.0 1.18 1.6499 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P13 compound treatment 655827.0 158000.0 0.94 580165.0 113000.0 0.64 1.1189 0.9828 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P14 compound treatment 514122.0 16200.0 0.1 320942.0 -146000.0 -0.83 -0.5198 -0.621 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P15 compound treatment 78191.0 -420000.0 -2.5 76823.0 -390000.0 -2.22 -3.336 -0.9983 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P16 compound treatment 519093.0 21200.0 0.13 435444.0 -31700.0 -0.18 -0.0385 -0.1749 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P17 compound treatment 480801.0 -17100.0 -0.1 421702.0 -45500.0 -0.26 -0.2549 -0.9172 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P18 compound treatment 518847.0 20900.0 0.12 484638.0 17500.0 0.1 0.1583 0.9938 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P19 compound treatment 495222.0 -2710.0 -0.02 536801.0 69600.0 0.4 0.2686 0.6778 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P20 compound treatment 433304.0 -64600.0 -0.38 468234.0 1070.0 0.01 -0.2676 -0.6958 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P21 compound treatment 451153.0 -46800.0 -0.28 513683.0 46500.0 0.26 -0.0098 -0.0254 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P22 compound treatment 489665.0 -8260.0 -0.05 410705.0 -56500.0 -0.32 -0.2618 -0.806 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P23 compound treatment 577111.0 79200.0 0.47 596795.0 130000.0 0.74 0.8545 0.9766 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2094 P24 compound treatment 615080.0 117000.0 0.7 629765.0 163000.0 0.92 1.1469 0.9903 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A01 compound treatment 422507.0 -95600.0 -0.57 581876.0 56000.0 0.32 -0.1771 -0.2718 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A02 compound treatment 558012.0 39900.0 0.24 615308.0 89400.0 0.51 0.5276 0.94 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A03 compound treatment 152656.0 -365000.0 -2.17 164078.0 -362000.0 -2.06 -2.9928 -0.9996 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A04 compound treatment 437337.0 -80700.0 -0.48 390066.0 -136000.0 -0.77 -0.886 -0.9739 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A05 compound treatment 184121.0 -334000.0 -1.99 269227.0 -257000.0 -1.46 -2.4375 -0.9885 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A06 compound treatment 567659.0 49600.0 0.3 638210.0 112000.0 0.64 0.6603 0.9385 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A07 compound treatment 556016.0 37900.0 0.23 571089.0 45200.0 0.26 0.3414 0.9979 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A08 compound treatment 151222.0 -367000.0 -2.18 168489.0 -357000.0 -2.03 -2.9811 -0.9994 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A09 compound treatment 265502.0 -253000.0 -1.5 606125.0 80200.0 0.46 -0.7403 -0.4713 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A10 compound treatment 312673.0 -205000.0 -1.22 583211.0 57300.0 0.33 -0.634 -0.5011 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A11 compound treatment 153985.0 -364000.0 -2.17 229691.0 -296000.0 -1.68 -2.7233 -0.9922 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A12 compound treatment 430896.0 -87200.0 -0.52 569196.0 43300.0 0.25 -0.1928 -0.3357 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A13 mock treatment 553773.0 35700.0 0.21 537461.0 11600.0 0.07 0.1967 0.8845 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A14 mock treatment 599888.0 81800.0 0.49 550638.0 24700.0 0.14 0.4437 0.8756 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A15 compound treatment 450686.0 -67400.0 -0.4 435977.0 -89900.0 -0.51 -0.6452 -0.9928 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A16 compound treatment 469327.0 -48700.0 -0.29 533548.0 7640.0 0.04 -0.1744 -0.5946 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A17 compound treatment 554902.0 36800.0 0.22 621243.0 95300.0 0.54 0.5383 0.9206 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A18 compound treatment 557491.0 39400.0 0.23 678006.0 152000.0 0.86 0.7775 0.8675 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A19 compound treatment 666826.0 149000.0 0.89 604322.0 78400.0 0.45 0.9413 0.9496 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A20 compound treatment 270639.0 -247000.0 -1.47 253045.0 -273000.0 -1.55 -2.1385 -0.9997 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A21 compound treatment 251082.0 -267000.0 -1.59 267689.0 -258000.0 -1.47 -2.1619 -0.9992 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A22 compound treatment 571192.0 53100.0 0.32 682982.0 157000.0 0.89 0.8552 0.9025 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A23 compound treatment 552802.0 34700.0 0.21 696387.0 170000.0 0.97 0.8317 0.839 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 A24 compound treatment 430929.0 -87100.0 -0.52 380539.0 -145000.0 -0.83 -0.9513 -0.9748 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B01 compound treatment 81867.0 -436000.0 -2.6 86506.0 -439000.0 -2.5 -3.6026 -0.9998 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B02 compound treatment 485565.0 -32500.0 -0.19 651515.0 126000.0 0.71 0.3683 0.4976 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B03 compound treatment 576046.0 58000.0 0.35 654971.0 129000.0 0.73 0.7629 0.9407 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B04 compound treatment 418787.0 -99300.0 -0.59 497224.0 -28700.0 -0.16 -0.5332 -0.8698 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B05 compound treatment 565587.0 47500.0 0.28 532643.0 6740.0 0.04 0.227 0.7956 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B06 compound treatment 346092.0 -172000.0 -1.02 390249.0 -136000.0 -0.77 -1.2693 -0.9903 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B07 compound treatment 435082.0 -83000.0 -0.49 445978.0 -79900.0 -0.45 -0.6707 -0.9991 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B08 compound treatment 283268.0 -235000.0 -1.4 273810.0 -252000.0 -1.43 -2.0019 -0.9999 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B09 compound treatment 519326.0 1250.0 0.01 447753.0 -78200.0 -0.44 -0.309 -0.6952 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B10 compound treatment 204708.0 -313000.0 -1.86 260030.0 -266000.0 -1.51 -2.3879 -0.9946 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B11 compound treatment 606676.0 88600.0 0.53 570114.0 44200.0 0.25 0.5506 0.9426 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B12 compound treatment 511825.0 -6250.0 -0.04 488070.0 -37800.0 -0.22 -0.1784 -0.8172 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B13 mock treatment 609904.0 91800.0 0.55 507532.0 -18400.0 -0.1 0.3126 0.5617 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B14 mock treatment 533489.0 15400.0 0.09 525877.0 -30.5 0.0 0.0647 0.7058 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B15 compound treatment 623077.0 105000.0 0.62 428450.0 -97500.0 -0.55 0.05 0.0599 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B16 compound treatment 513503.0 -4570.0 -0.03 434395.0 -91500.0 -0.52 -0.3872 -0.7431 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B17 compound treatment 502010.0 -16100.0 -0.1 497308.0 -28600.0 -0.16 -0.1826 -0.9679 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B18 compound treatment 557606.0 39500.0 0.24 572122.0 46200.0 0.26 0.3522 0.9985 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B19 compound treatment 251564.0 -267000.0 -1.59 341266.0 -185000.0 -1.05 -1.864 -0.9799 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B20 compound treatment 514137.0 -3940.0 -0.02 476038.0 -49900.0 -0.28 -0.2171 -0.7629 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B21 compound treatment 497463.0 -20600.0 -0.12 505482.0 -20400.0 -0.12 -0.1689 -0.9996 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B22 compound treatment 573841.0 55800.0 0.33 524689.0 -1220.0 -0.01 0.2298 0.6922 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B23 compound treatment 460578.0 -57500.0 -0.34 477606.0 -48300.0 -0.27 -0.4362 -0.9941 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 B24 compound treatment 679579.0 162000.0 0.96 567013.0 41100.0 0.23 0.8449 0.8542 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C01 compound treatment 565865.0 47800.0 0.28 592912.0 67000.0 0.38 0.4706 0.9896 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C02 compound treatment 601241.0 83200.0 0.49 534649.0 8740.0 0.05 0.3851 0.7742 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C03 compound treatment 463412.0 -54700.0 -0.33 498805.0 -27100.0 -0.15 -0.339 -0.9418 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C04 compound treatment 13100.0 -505000.0 -3.01 66656.0 -459000.0 -2.61 -3.9718 -0.9976 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C05 compound treatment 394665.0 -123000.0 -0.73 597513.0 71600.0 0.41 -0.2314 -0.2756 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C06 compound treatment 463122.0 -55000.0 -0.33 503703.0 -22200.0 -0.13 -0.3205 -0.9143 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C07 compound treatment 559722.0 41600.0 0.25 488131.0 -37800.0 -0.21 0.0234 0.0712 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C08 compound treatment 80637.0 -437000.0 -2.6 252636.0 -273000.0 -1.55 -2.9397 -0.9696 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C09 compound treatment 553305.0 35200.0 0.21 523204.0 -2700.0 -0.02 0.1374 0.6535 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C10 compound treatment 60778.0 -457000.0 -2.72 60129.0 -466000.0 -2.65 -3.7974 -0.9999 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C11 mock treatment 516031.0 -2040.0 -0.01 465508.0 -60400.0 -0.34 -0.2515 -0.7317 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C12 mock treatment 133692.0 -384000.0 -2.29 484212.0 -41700.0 -0.24 -1.7853 -0.7762 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C13 compound treatment 521532.0 3460.0 0.02 543752.0 17800.0 0.1 0.0863 0.8335 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C14 compound treatment 232771.0 -285000.0 -1.7 229759.0 -296000.0 -1.68 -2.3915 -1.0 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C15 mock treatment 568381.0 50300.0 0.3 500154.0 -25800.0 -0.15 0.1081 0.3245 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C16 mock treatment 531937.0 13900.0 0.08 445287.0 -80600.0 -0.46 -0.2658 -0.5707 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C17 compound treatment 480051.0 -38000.0 -0.23 474385.0 -51500.0 -0.29 -0.3672 -0.9919 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C18 compound treatment 278921.0 -239000.0 -1.42 220373.0 -306000.0 -1.74 -2.235 -0.9951 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C19 compound treatment 453140.0 -64900.0 -0.39 557416.0 31500.0 0.18 -0.1466 -0.3441 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C20 compound treatment 498602.0 -19500.0 -0.12 492953.0 -33000.0 -0.19 -0.2145 -0.9733 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C21 compound treatment 337877.0 -180000.0 -1.07 363672.0 -162000.0 -0.92 -1.4107 -0.9972 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C22 compound treatment 498601.0 -19500.0 -0.12 547500.0 21600.0 0.12 0.0049 0.0289 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C23 compound treatment 624110.0 106000.0 0.63 589198.0 63300.0 0.36 0.7007 0.9645 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 C24 compound treatment 492812.0 -25300.0 -0.15 594159.0 68300.0 0.39 0.1681 0.404 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D01 compound treatment 336604.0 -181000.0 -1.08 370732.0 -155000.0 -0.88 -1.3877 -0.995 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D02 compound treatment 239538.0 -279000.0 -1.66 253674.0 -272000.0 -1.55 -2.2669 -0.9994 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D03 compound treatment 461355.0 -56700.0 -0.34 584049.0 58100.0 0.33 -0.0049 -0.0104 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D04 compound treatment 427667.0 -90400.0 -0.54 568787.0 42900.0 0.24 -0.208 -0.3522 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D05 compound treatment 470064.0 -48000.0 -0.29 515698.0 -10200.0 -0.06 -0.2431 -0.8338 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D06 compound treatment 176139.0 -342000.0 -2.03 226414.0 -299000.0 -1.7 -2.6433 -0.9961 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D07 compound treatment 545187.0 27100.0 0.16 504772.0 -21100.0 -0.12 0.0291 0.1447 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D08 compound treatment 197835.0 -320000.0 -1.91 465497.0 -60400.0 -0.34 -1.5906 -0.8213 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D09 compound treatment 544067.0 26000.0 0.15 489136.0 -36800.0 -0.21 -0.0385 -0.1479 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D10 compound treatment 96873.0 -421000.0 -2.51 181353.0 -345000.0 -1.96 -3.158 -0.9926 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D11 mock treatment 426128.0 -91900.0 -0.55 468085.0 -57800.0 -0.33 -0.6194 -0.9703 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D12 mock treatment 539654.0 21600.0 0.13 457287.0 -68600.0 -0.39 -0.1851 -0.4506 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D13 compound treatment 573370.0 55300.0 0.33 509452.0 -16500.0 -0.09 0.1665 0.4867 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D14 compound treatment 408645.0 -109000.0 -0.65 469293.0 -56600.0 -0.32 -0.6882 -0.9472 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D15 mock treatment 475013.0 -43100.0 -0.26 487618.0 -38300.0 -0.22 -0.3352 -0.9967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D16 mock treatment 440850.0 -77200.0 -0.46 457587.0 -68300.0 -0.39 -0.5997 -0.9965 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D17 compound treatment 417130.0 -101000.0 -0.6 468478.0 -57400.0 -0.33 -0.6557 -0.959 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D18 compound treatment 257809.0 -260000.0 -1.55 470858.0 -55000.0 -0.31 -1.3166 -0.8332 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D19 compound treatment 437512.0 -80600.0 -0.48 508158.0 -17700.0 -0.1 -0.4104 -0.8376 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D20 compound treatment 461633.0 -56400.0 -0.34 443451.0 -82500.0 -0.47 -0.5691 -0.9866 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D21 compound treatment 495585.0 -22500.0 -0.13 555059.0 29200.0 0.17 0.0226 0.106 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D22 compound treatment 203385.0 -315000.0 -1.87 255255.0 -271000.0 -1.54 -2.4126 -0.9953 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D23 compound treatment 551660.0 33600.0 0.2 428926.0 -97000.0 -0.55 -0.2486 -0.4239 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 D24 compound treatment 137999.0 -380000.0 -2.26 120382.0 -406000.0 -2.31 -3.2301 -1.0 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E01 mock treatment 536716.0 18600.0 0.11 458537.0 -67400.0 -0.38 -0.1925 -0.4825 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E02 mock treatment 522585.0 4510.0 0.03 482827.0 -43100.0 -0.24 -0.1543 -0.6259 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E03 compound treatment 525176.0 7100.0 0.04 537096.0 11200.0 0.06 0.0749 0.9803 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E04 compound treatment 349854.0 -168000.0 -1.0 417838.0 -108000.0 -0.61 -1.1425 -0.9725 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E05 compound treatment 153842.0 -364000.0 -2.17 513538.0 -12400.0 -0.07 -1.5825 -0.7297 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E06 compound treatment 61959.0 -456000.0 -2.71 70723.0 -455000.0 -2.59 -3.7498 -0.9997 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E07 compound treatment 438434.0 -79600.0 -0.47 478885.0 -47000.0 -0.27 -0.5242 -0.9633 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E08 compound treatment 454788.0 -63300.0 -0.38 502904.0 -23000.0 -0.13 -0.3588 -0.9 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E09 mock treatment 491046.0 -27000.0 -0.16 496732.0 -29200.0 -0.17 -0.2311 -0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E10 mock treatment 449542.0 -68500.0 -0.41 478749.0 -47200.0 -0.27 -0.478 -0.9793 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E11 compound treatment 457255.0 -60800.0 -0.36 484176.0 -41700.0 -0.24 -0.4238 -0.979 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E12 compound treatment 357049.0 -161000.0 -0.96 349509.0 -176000.0 -1.0 -1.387 -0.9997 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E13 compound treatment 169527.0 -349000.0 -2.07 471099.0 -54800.0 -0.31 -1.6872 -0.8043 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E14 compound treatment 417188.0 -101000.0 -0.6 494431.0 -31500.0 -0.18 -0.5511 -0.8797 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E15 compound treatment 54593.0 -463000.0 -2.76 58994.0 -467000.0 -2.66 -3.828 -0.9998 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E16 compound treatment 501705.0 -16400.0 -0.1 559239.0 33300.0 0.19 0.0651 0.3057 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E17 mock treatment 409427.0 -109000.0 -0.65 493344.0 -32600.0 -0.19 -0.5882 -0.8745 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E18 mock treatment 451934.0 -66100.0 -0.39 494813.0 -31100.0 -0.18 -0.4034 -0.9348 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E19 compound treatment 453672.0 -64400.0 -0.38 491555.0 -34400.0 -0.2 -0.4092 -0.9511 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E20 compound treatment 400048.0 -118000.0 -0.7 394933.0 -131000.0 -0.74 -1.0234 -0.9996 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E21 compound treatment 403248.0 -115000.0 -0.68 482760.0 -43100.0 -0.25 -0.6567 -0.9045 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E22 compound treatment 550347.0 32300.0 0.19 524915.0 -993.0 -0.01 0.1318 0.686 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E23 compound treatment 395463.0 -123000.0 -0.73 504711.0 -21200.0 -0.12 -0.6012 -0.8129 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 E24 compound treatment 462958.0 -55100.0 -0.33 633395.0 107000.0 0.61 0.2003 0.2887 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F01 mock treatment 600401.0 82300.0 0.49 532727.0 6820.0 0.04 0.3739 0.7607 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F02 mock treatment 382067.0 -136000.0 -0.81 542193.0 16300.0 0.09 -0.5069 -0.6221 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F03 compound treatment 391542.0 -127000.0 -0.75 508951.0 -17000.0 -0.1 -0.6007 -0.7912 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F04 compound treatment 213167.0 -305000.0 -1.81 358667.0 -167000.0 -0.95 -1.9556 -0.9545 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F05 compound treatment 377841.0 -140000.0 -0.83 462211.0 -63700.0 -0.36 -0.8463 -0.9302 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F06 compound treatment 531803.0 13700.0 0.08 495263.0 -30600.0 -0.17 -0.0655 -0.3401 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F07 compound treatment 99588.0 -418000.0 -2.49 231458.0 -294000.0 -1.67 -2.9451 -0.9813 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F08 compound treatment 483170.0 -34900.0 -0.21 498346.0 -27600.0 -0.16 -0.2577 -0.9904 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F09 mock treatment 165827.0 -352000.0 -2.1 539607.0 13700.0 0.08 -1.4273 -0.6804 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F10 mock treatment 164298.0 -354000.0 -2.11 528466.0 2560.0 0.01 -1.4785 -0.7022 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F11 compound treatment 505145.0 -12900.0 -0.08 547984.0 22100.0 0.13 0.0344 0.2334 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F12 compound treatment 151798.0 -366000.0 -2.18 249386.0 -277000.0 -1.57 -2.6533 -0.9872 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F13 compound treatment 480860.0 -37200.0 -0.22 493211.0 -32700.0 -0.19 -0.2881 -0.9962 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F14 compound treatment 498649.0 -19400.0 -0.12 504149.0 -21800.0 -0.12 -0.1692 -0.9994 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F15 compound treatment 51738.0 -466000.0 -2.78 60742.0 -465000.0 -2.65 -3.833 -0.9997 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F16 compound treatment 211137.0 -307000.0 -1.83 491207.0 -34700.0 -0.2 -1.4312 -0.779 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F17 mock treatment 524889.0 6810.0 0.04 525511.0 -397.0 0.0 0.0271 0.6668 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F18 mock treatment 504132.0 -13900.0 -0.08 593591.0 67700.0 0.38 0.2135 0.5422 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F19 compound treatment 216387.0 -302000.0 -1.8 242630.0 -283000.0 -1.61 -2.4087 -0.9985 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F20 compound treatment 253426.0 -265000.0 -1.58 256372.0 -270000.0 -1.53 -2.1976 -0.9999 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F21 compound treatment 305225.0 -213000.0 -1.27 351298.0 -175000.0 -0.99 -1.5979 -0.9927 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F22 compound treatment 164857.0 -353000.0 -2.1 148711.0 -377000.0 -2.15 -3.0032 -0.9999 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F23 compound treatment 409420.0 -109000.0 -0.65 582224.0 56300.0 0.32 -0.2308 -0.3198 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 F24 compound treatment 414654.0 -103000.0 -0.62 460620.0 -65300.0 -0.37 -0.6978 -0.9707 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G01 compound treatment 343935.0 -174000.0 -1.04 322666.0 -203000.0 -1.16 -1.5501 -0.9985 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G02 compound treatment 347861.0 -170000.0 -1.01 550687.0 24800.0 0.14 -0.6167 -0.6029 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G03 mock treatment 216398.0 -302000.0 -1.8 532233.0 6330.0 0.04 -1.2441 -0.6928 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G04 mock treatment 493703.0 -24400.0 -0.15 485107.0 -40800.0 -0.23 -0.2666 -0.9744 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G05 compound treatment 473452.0 -44600.0 -0.27 485834.0 -40100.0 -0.23 -0.3489 -0.9971 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G06 compound treatment 550624.0 32500.0 0.19 490658.0 -35200.0 -0.2 -0.0048 -0.0171 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G07 compound treatment 539195.0 21100.0 0.13 467204.0 -58700.0 -0.33 -0.1472 -0.4126 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G08 compound treatment 435379.0 -82700.0 -0.49 528937.0 3030.0 0.02 -0.3358 -0.6819 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G09 compound treatment 181125.0 -337000.0 -2.01 545063.0 19200.0 0.11 -1.341 -0.6677 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G10 compound treatment 188191.0 -330000.0 -1.96 517969.0 -7940.0 -0.05 -1.4202 -0.7232 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G11 compound treatment 471761.0 -46300.0 -0.28 472926.0 -53000.0 -0.3 -0.4079 -0.999 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G12 compound treatment 52961.0 -465000.0 -2.77 211316.0 -315000.0 -1.79 -3.2223 -0.9777 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G13 compound treatment 462995.0 -55100.0 -0.33 569064.0 43200.0 0.25 -0.0583 -0.1423 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G14 compound treatment 150018.0 -368000.0 -2.19 501068.0 -24800.0 -0.14 -1.6488 -0.7511 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G15 compound treatment 540443.0 22400.0 0.13 346104.0 -180000.0 -1.02 -0.6289 -0.6099 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G16 compound treatment 210987.0 -307000.0 -1.83 526736.0 828.0 0.0 -1.289 -0.7053 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G17 compound treatment 398931.0 -119000.0 -0.71 154432.0 -371000.0 -2.11 -1.9951 -0.8954 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G18 compound treatment 133470.0 -385000.0 -2.29 128399.0 -398000.0 -2.26 -3.217 -1.0 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G19 mock treatment 459007.0 -59100.0 -0.35 447444.0 -78500.0 -0.45 -0.5641 -0.993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G20 mock treatment 510860.0 -7210.0 -0.04 506873.0 -19000.0 -0.11 -0.1069 -0.918 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G21 compound treatment 486826.0 -31200.0 -0.19 489121.0 -36800.0 -0.21 -0.2794 -0.9983 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G22 compound treatment 563949.0 45900.0 0.27 595306.0 69400.0 0.39 0.4721 0.9838 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G23 compound treatment 635404.0 117000.0 0.7 503671.0 -22200.0 -0.13 0.4043 0.5698 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 G24 compound treatment 489537.0 -28500.0 -0.17 590085.0 64200.0 0.36 0.138 0.3428 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H01 compound treatment 449137.0 -68900.0 -0.41 508577.0 -17300.0 -0.1 -0.3598 -0.8527 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H02 compound treatment 51687.0 -466000.0 -2.78 198164.0 -328000.0 -1.86 -3.2806 -0.9812 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H03 mock treatment 262440.0 -256000.0 -1.52 468757.0 -57200.0 -0.33 -1.3056 -0.8392 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H04 mock treatment 641952.0 124000.0 0.74 565488.0 39600.0 0.23 0.6805 0.8828 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H05 compound treatment 423539.0 -94500.0 -0.56 564547.0 38600.0 0.22 -0.2425 -0.4014 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H06 compound treatment 244551.0 -274000.0 -1.63 227647.0 -298000.0 -1.7 -2.3504 -0.9998 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H07 compound treatment 243544.0 -275000.0 -1.63 539069.0 13200.0 0.07 -1.1024 -0.674 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H08 compound treatment 395705.0 -122000.0 -0.73 396451.0 -129000.0 -0.74 -1.0355 -1.0 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H09 compound treatment 548494.0 30400.0 0.18 553622.0 27700.0 0.16 0.2395 0.9976 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H10 compound treatment 320201.0 -198000.0 -1.18 373628.0 -152000.0 -0.87 -1.445 -0.9886 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H11 compound treatment 430928.0 -87100.0 -0.52 557385.0 31500.0 0.18 -0.2402 -0.4377 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H12 compound treatment 435621.0 -82500.0 -0.49 489730.0 -36200.0 -0.21 -0.4925 -0.9255 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H13 compound treatment 506337.0 -11700.0 -0.07 535141.0 9230.0 0.05 -0.0123 -0.1403 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H14 compound treatment 458217.0 -59900.0 -0.36 471542.0 -54400.0 -0.31 -0.4705 -0.9975 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H15 compound treatment 475186.0 -42900.0 -0.26 584692.0 58800.0 0.33 0.0559 0.1329 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H16 compound treatment 460876.0 -57200.0 -0.34 509783.0 -16100.0 -0.09 -0.3055 -0.8667 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H17 compound treatment 478164.0 -39900.0 -0.24 544362.0 18500.0 0.1 -0.0937 -0.361 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H18 compound treatment 489666.0 -28400.0 -0.17 532091.0 6180.0 0.04 -0.0947 -0.5483 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H19 mock treatment 520001.0 1930.0 0.01 521925.0 -3980.0 -0.02 -0.0079 -0.3114 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H20 mock treatment 449356.0 -68700.0 -0.41 525688.0 -220.0 0.0 -0.2901 -0.7093 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H21 compound treatment 538154.0 20100.0 0.12 530909.0 5000.0 0.03 0.1046 0.8516 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H22 compound treatment 198041.0 -320000.0 -1.9 271294.0 -255000.0 -1.45 -2.3706 -0.9908 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H23 compound treatment 518438.0 364.0 0.0 642351.0 116000.0 0.66 0.4698 0.7094 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 H24 compound treatment 483435.0 -34600.0 -0.21 540017.0 14100.0 0.08 -0.089 -0.4025 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I01 compound treatment 563865.0 45800.0 0.27 498849.0 -27100.0 -0.15 0.0839 0.2681 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I02 compound treatment 363112.0 -155000.0 -0.92 540520.0 14600.0 0.08 -0.5934 -0.6408 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I03 compound treatment 567037.0 49000.0 0.29 506598.0 -19300.0 -0.11 0.1284 0.4123 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I04 compound treatment 557958.0 39900.0 0.24 458483.0 -67400.0 -0.38 -0.1033 -0.229 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I05 mock treatment 524361.0 6290.0 0.04 485861.0 -40000.0 -0.23 -0.1346 -0.5831 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I06 mock treatment 506411.0 -11700.0 -0.07 464320.0 -61600.0 -0.35 -0.2967 -0.8311 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I07 compound treatment 462855.0 -55200.0 -0.33 451443.0 -74500.0 -0.42 -0.5318 -0.9921 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I08 compound treatment 542542.0 24500.0 0.15 504044.0 -21900.0 -0.12 0.0151 0.0786 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I09 compound treatment 56656.0 -461000.0 -2.75 128504.0 -397000.0 -2.26 -3.5398 -0.9953 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I10 compound treatment 507410.0 -10700.0 -0.06 524204.0 -1700.0 -0.01 -0.0517 -0.8057 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I11 compound treatment 503557.0 -14500.0 -0.09 514878.0 -11000.0 -0.06 -0.1054 -0.9876 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I12 compound treatment 540788.0 22700.0 0.14 489084.0 -36800.0 -0.21 -0.0525 -0.2106 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I13 compound treatment 499026.0 -19000.0 -0.11 438397.0 -87500.0 -0.5 -0.4321 -0.8465 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I14 compound treatment 416511.0 -102000.0 -0.6 561301.0 35400.0 0.2 -0.2851 -0.4475 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I15 compound treatment 562156.0 44100.0 0.26 564260.0 38400.0 0.22 0.3397 0.9958 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I16 compound treatment 275173.0 -243000.0 -1.45 339717.0 -186000.0 -1.06 -1.7709 -0.9883 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I17 compound treatment 479203.0 -38900.0 -0.23 525554.0 -354.0 0.0 -0.165 -0.7132 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I18 compound treatment 531515.0 13400.0 0.08 571005.0 45100.0 0.26 0.2379 0.8856 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I19 compound treatment 430050.0 -88000.0 -0.52 447395.0 -78500.0 -0.45 -0.6861 -0.9968 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I20 compound treatment 519422.0 1350.0 0.01 519167.0 -6740.0 -0.04 -0.0214 -0.5473 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I21 mock treatment 468931.0 -49100.0 -0.29 539950.0 14000.0 0.08 -0.1503 -0.4959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I22 mock treatment 497806.0 -20300.0 -0.12 520214.0 -5690.0 -0.03 -0.1082 -0.8662 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I23 compound treatment 476534.0 -41500.0 -0.25 470633.0 -55300.0 -0.31 -0.3971 -0.9929 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 I24 compound treatment 552037.0 34000.0 0.2 628870.0 103000.0 0.59 0.557 0.8991 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J01 compound treatment 589270.0 71200.0 0.42 478019.0 -47900.0 -0.27 0.107 0.2125 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J02 compound treatment 452276.0 -65800.0 -0.39 492582.0 -33300.0 -0.19 -0.4109 -0.9445 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J03 compound treatment 455209.0 -62900.0 -0.37 432493.0 -93400.0 -0.53 -0.6402 -0.9853 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J04 compound treatment 526103.0 8030.0 0.05 526567.0 659.0 0.0 0.0364 0.7603 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J05 mock treatment 473406.0 -44700.0 -0.27 464431.0 -61500.0 -0.35 -0.4352 -0.9909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J06 mock treatment 476100.0 -42000.0 -0.25 456077.0 -69800.0 -0.4 -0.4574 -0.975 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J07 compound treatment 238585.0 -279000.0 -1.66 252161.0 -274000.0 -1.56 -2.2769 -0.9995 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J08 compound treatment 212527.0 -306000.0 -1.82 236667.0 -289000.0 -1.64 -2.4489 -0.9987 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J09 compound treatment 57165.0 -461000.0 -2.74 62066.0 -464000.0 -2.64 -3.8048 -0.9998 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J10 compound treatment 514277.0 -3800.0 -0.02 548392.0 22500.0 0.13 0.0744 0.5732 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J11 compound treatment 441922.0 -76200.0 -0.45 457836.0 -68100.0 -0.39 -0.5942 -0.9969 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J12 compound treatment 393673.0 -124000.0 -0.74 549761.0 23900.0 0.14 -0.4276 -0.5681 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J13 compound treatment 50953.0 -467000.0 -2.78 55576.0 -470000.0 -2.67 -3.8571 -0.9998 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J14 compound treatment 246980.0 -271000.0 -1.61 316595.0 -209000.0 -1.19 -1.9825 -0.9888 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J15 compound treatment 492434.0 -25600.0 -0.15 525760.0 -148.0 0.0 -0.1085 -0.711 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J16 compound treatment 68885.0 -449000.0 -2.67 90058.0 -436000.0 -2.48 -3.6429 -0.9993 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J17 compound treatment 57518.0 -461000.0 -2.74 54902.0 -471000.0 -2.68 -3.8321 -0.9999 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J18 compound treatment 467884.0 -50200.0 -0.3 529864.0 3960.0 0.02 -0.1953 -0.652 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J19 compound treatment 402234.0 -116000.0 -0.69 423964.0 -102000.0 -0.58 -0.8974 -0.9963 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J20 compound treatment 526461.0 8390.0 0.05 461017.0 -64900.0 -0.37 -0.2256 -0.6059 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J21 mock treatment 493344.0 -24700.0 -0.15 483250.0 -42700.0 -0.24 -0.2756 -0.9713 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J22 mock treatment 489137.0 -28900.0 -0.17 575891.0 50000.0 0.28 0.0792 0.2383 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J23 compound treatment 642877.0 125000.0 0.74 569264.0 43400.0 0.25 0.6995 0.8939 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 J24 compound treatment 572743.0 54700.0 0.33 651009.0 125000.0 0.71 0.7331 0.9371 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K01 compound treatment 263834.0 -254000.0 -1.51 276329.0 -250000.0 -1.42 -2.0735 -0.9995 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K02 compound treatment 577855.0 59800.0 0.36 362927.0 -163000.0 -0.93 -0.4038 -0.4067 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K03 compound treatment 463548.0 -54500.0 -0.32 417818.0 -108000.0 -0.61 -0.6641 -0.9554 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K04 compound treatment 59271.0 -459000.0 -2.73 74667.0 -451000.0 -2.57 -3.7453 -0.9995 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K05 compound treatment 461072.0 -57000.0 -0.34 438404.0 -87500.0 -0.5 -0.5917 -0.9826 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K06 compound treatment 64486.0 -454000.0 -2.7 72435.0 -453000.0 -2.58 -3.7323 -0.9997 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K07 mock treatment 566546.0 48500.0 0.29 659219.0 133000.0 0.76 0.74 0.9124 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K08 mock treatment 409379.0 -109000.0 -0.65 508717.0 -17200.0 -0.1 -0.5265 -0.8048 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K09 compound treatment 619322.0 101000.0 0.6 623087.0 97200.0 0.55 0.8169 0.9991 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K10 compound treatment 561457.0 43400.0 0.26 499294.0 -26600.0 -0.15 0.0756 0.2524 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K11 compound treatment 393342.0 -125000.0 -0.74 443631.0 -82300.0 -0.47 -0.8558 -0.9752 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K12 compound treatment 59305.0 -459000.0 -2.73 61078.0 -465000.0 -2.64 -3.7998 -0.9999 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K13 compound treatment 566680.0 48600.0 0.29 618034.0 92100.0 0.52 0.575 0.9608 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K14 compound treatment 440816.0 -77300.0 -0.46 430792.0 -95100.0 -0.54 -0.7076 -0.9967 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K15 mock treatment 523493.0 5420.0 0.03 544278.0 18400.0 0.1 0.0967 0.8842 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K16 mock treatment 551970.0 33900.0 0.2 579435.0 53500.0 0.3 0.3579 0.98 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K17 compound treatment 159851.0 -358000.0 -2.13 199839.0 -326000.0 -1.85 -2.8187 -0.9976 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K18 compound treatment 60306.0 -458000.0 -2.72 57506.0 -468000.0 -2.66 -3.8099 -0.9999 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K19 compound treatment 535495.0 17400.0 0.1 554726.0 28800.0 0.16 0.1892 0.9756 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K20 compound treatment 535217.0 17100.0 0.1 546415.0 20500.0 0.12 0.1546 0.9978 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K21 compound treatment 565572.0 47500.0 0.28 615788.0 89900.0 0.51 0.5613 0.961 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K22 compound treatment 541145.0 23100.0 0.14 617864.0 92000.0 0.52 0.4669 0.8635 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K23 mock treatment 510111.0 -7960.0 -0.05 605394.0 79500.0 0.45 0.2861 0.6295 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 K24 mock treatment 480719.0 -37400.0 -0.22 598252.0 72300.0 0.41 0.1337 0.2859 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L01 compound treatment 599436.0 81400.0 0.48 534185.0 8280.0 0.05 0.3757 0.7722 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L02 compound treatment 234333.0 -284000.0 -1.69 228373.0 -298000.0 -1.69 -2.3905 -1.0 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L03 compound treatment 533721.0 15600.0 0.09 503720.0 -22200.0 -0.13 -0.0234 -0.149 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L04 compound treatment 568714.0 50600.0 0.3 534179.0 8270.0 0.05 0.2464 0.8077 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L05 compound treatment 642928.0 125000.0 0.74 549335.0 23400.0 0.13 0.6196 0.8208 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L06 compound treatment 446278.0 -71800.0 -0.43 421607.0 -104000.0 -0.59 -0.7215 -0.987 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L07 mock treatment 527730.0 9660.0 0.06 489165.0 -36700.0 -0.21 -0.1071 -0.4943 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L08 mock treatment 500919.0 -17200.0 -0.1 508146.0 -17800.0 -0.1 -0.1436 -1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L09 compound treatment 57145.0 -461000.0 -2.74 63612.0 -462000.0 -2.63 -3.7987 -0.9998 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L10 compound treatment 463142.0 -54900.0 -0.33 502598.0 -23300.0 -0.13 -0.3249 -0.921 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L11 compound treatment 568759.0 50700.0 0.3 600717.0 74800.0 0.43 0.5141 0.9858 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L12 compound treatment 203129.0 -315000.0 -1.87 65904.0 -460000.0 -2.62 -3.1751 -0.9866 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L13 compound treatment 281428.0 -237000.0 -1.41 438174.0 -87700.0 -0.5 -1.3487 -0.9026 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L14 compound treatment 632062.0 114000.0 0.68 286972.0 -239000.0 -1.36 -0.4811 -0.3168 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L15 mock treatment 586570.0 68500.0 0.41 515337.0 -10600.0 -0.06 0.2457 0.5964 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L16 mock treatment 583480.0 65400.0 0.39 572560.0 46700.0 0.27 0.4628 0.9825 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L17 compound treatment 545809.0 27700.0 0.17 277691.0 -248000.0 -1.41 -0.8814 -0.6202 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L18 compound treatment 71159.0 -447000.0 -2.66 229313.0 -297000.0 -1.69 -3.0734 -0.9758 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L19 compound treatment 535766.0 17700.0 0.11 587880.0 62000.0 0.35 0.3237 0.8799 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L20 compound treatment 540201.0 22100.0 0.13 578866.0 53000.0 0.3 0.3061 0.9312 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L21 compound treatment 408527.0 -110000.0 -0.65 467493.0 -58400.0 -0.33 -0.6959 -0.9511 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L22 compound treatment 502413.0 -15700.0 -0.09 559386.0 33500.0 0.19 0.0687 0.3242 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L23 mock treatment 479594.0 -38500.0 -0.23 553142.0 27200.0 0.15 -0.0524 -0.1896 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 L24 mock treatment 516452.0 -1620.0 -0.01 577504.0 51600.0 0.29 0.2006 0.6835 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M01 compound treatment 567695.0 49600.0 0.3 206865.0 -319000.0 -1.81 -1.0741 -0.5843 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M02 compound treatment 553036.0 35000.0 0.21 499708.0 -26200.0 -0.15 0.0418 0.1632 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M03 compound treatment 546599.0 28500.0 0.17 480410.0 -45500.0 -0.26 -0.0629 -0.2033 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M04 compound treatment 563537.0 45500.0 0.27 573729.0 47800.0 0.27 0.3836 1.0 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M05 compound treatment 56738.0 -461000.0 -2.75 63091.0 -463000.0 -2.63 -3.8025 -0.9998 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M06 compound treatment 389493.0 -129000.0 -0.77 535249.0 9340.0 0.05 -0.5035 -0.6564 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M07 compound treatment 288253.0 -230000.0 -1.37 566416.0 40500.0 0.23 -0.8043 -0.5798 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M08 compound treatment 527353.0 9280.0 0.06 480986.0 -44900.0 -0.26 -0.1416 -0.5417 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M09 mock treatment 602714.0 84600.0 0.5 567853.0 41900.0 0.24 0.5249 0.9417 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M10 mock treatment 520579.0 2500.0 0.01 567908.0 42000.0 0.24 0.1794 0.7498 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M11 compound treatment 58314.0 -460000.0 -2.74 59487.0 -466000.0 -2.65 -3.8103 -0.9999 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M12 compound treatment 60764.0 -457000.0 -2.72 63357.0 -463000.0 -2.63 -3.7845 -0.9999 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M13 mock treatment 553812.0 35700.0 0.21 594296.0 68400.0 0.39 0.4254 0.9597 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M14 mock treatment 541829.0 23800.0 0.14 543500.0 17600.0 0.1 0.1707 0.9857 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M15 compound treatment 569346.0 51300.0 0.31 596252.0 70300.0 0.4 0.4986 0.9911 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M16 compound treatment 600519.0 82400.0 0.49 567288.0 41400.0 0.24 0.5133 0.9434 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M17 compound treatment 509654.0 -8420.0 -0.05 500622.0 -25300.0 -0.14 -0.1371 -0.9004 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M18 compound treatment 535567.0 17500.0 0.1 573690.0 47800.0 0.27 0.2658 0.9133 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M19 compound treatment 556065.0 38000.0 0.23 569040.0 43100.0 0.25 0.3333 0.9992 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M20 compound treatment 423607.0 -94500.0 -0.56 471590.0 -54300.0 -0.31 -0.616 -0.9602 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M21 compound treatment 507581.0 -10500.0 -0.06 537570.0 11700.0 0.07 0.0027 0.0301 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M22 compound treatment 503684.0 -14400.0 -0.09 609063.0 83200.0 0.47 0.2738 0.5698 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M23 compound treatment 505252.0 -12800.0 -0.08 627170.0 101000.0 0.58 0.3532 0.6081 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 M24 compound treatment 426046.0 -92000.0 -0.55 503858.0 -22000.0 -0.13 -0.4759 -0.8471 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N01 compound treatment 543712.0 25600.0 0.15 578089.0 52200.0 0.3 0.3177 0.9522 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N02 compound treatment 561209.0 43100.0 0.26 502026.0 -23900.0 -0.14 0.0855 0.2944 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N03 compound treatment 574145.0 56100.0 0.33 602303.0 76400.0 0.43 0.5432 0.9915 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N04 compound treatment 357119.0 -161000.0 -0.96 324916.0 -201000.0 -1.14 -1.4856 -0.9961 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N05 compound treatment 656357.0 138000.0 0.82 609886.0 84000.0 0.48 0.9196 0.9665 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N06 compound treatment 237332.0 -281000.0 -1.67 233637.0 -292000.0 -1.66 -2.3567 -1.0 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N07 compound treatment 598559.0 80500.0 0.48 480774.0 -45100.0 -0.26 0.1572 0.2893 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N08 compound treatment 283167.0 -235000.0 -1.4 514547.0 -11400.0 -0.06 -1.0342 -0.739 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N09 mock treatment 650661.0 133000.0 0.79 575615.0 49700.0 0.28 0.7578 0.9042 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N10 mock treatment 658076.0 140000.0 0.83 596900.0 71000.0 0.4 0.8746 0.9447 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N11 compound treatment 599125.0 81100.0 0.48 529561.0 3650.0 0.02 0.3558 0.7369 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N12 compound treatment 268234.0 -250000.0 -1.49 285920.0 -240000.0 -1.36 -2.0164 -0.9991 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N13 mock treatment 616686.0 98600.0 0.59 571438.0 45500.0 0.26 0.5981 0.9324 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N14 mock treatment 607349.0 89300.0 0.53 581035.0 55100.0 0.31 0.5974 0.9683 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N15 compound treatment 52287.0 -466000.0 -2.77 54059.0 -472000.0 -2.68 -3.8575 -0.9999 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N16 compound treatment 543898.0 25800.0 0.15 540160.0 14300.0 0.08 0.166 0.9553 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N17 compound treatment 333716.0 -184000.0 -1.1 369459.0 -156000.0 -0.89 -1.4049 -0.9946 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N18 compound treatment 502126.0 -15900.0 -0.09 497898.0 -28000.0 -0.16 -0.1797 -0.9694 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N19 compound treatment 572498.0 54400.0 0.32 528640.0 2730.0 0.02 0.24 0.7402 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N20 compound treatment 323601.0 -194000.0 -1.16 293821.0 -232000.0 -1.32 -1.7517 -0.9979 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N21 compound treatment 610961.0 92900.0 0.55 564695.0 38800.0 0.22 0.5469 0.9188 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N22 compound treatment 568403.0 50300.0 0.3 569995.0 44100.0 0.25 0.3891 0.9961 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N23 compound treatment 495994.0 -22100.0 -0.13 514791.0 -11100.0 -0.06 -0.1376 -0.9437 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 N24 compound treatment 543351.0 25300.0 0.15 676436.0 151000.0 0.86 0.7117 0.8188 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O01 compound treatment 475093.0 -43000.0 -0.26 553369.0 27500.0 0.16 -0.0705 -0.2351 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O02 compound treatment 283346.0 -235000.0 -1.4 290618.0 -235000.0 -1.34 -1.9339 -0.9998 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O03 compound treatment 487924.0 -30200.0 -0.18 525964.0 56.5 0.0 -0.1267 -0.7058 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O04 compound treatment 391055.0 -127000.0 -0.76 437620.0 -88300.0 -0.5 -0.8896 -0.9802 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O05 compound treatment 546485.0 28400.0 0.17 445938.0 -80000.0 -0.45 -0.202 -0.4164 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O06 compound treatment 438299.0 -79800.0 -0.47 451710.0 -74200.0 -0.42 -0.6341 -0.9983 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O07 compound treatment 580973.0 62900.0 0.37 533053.0 7150.0 0.04 0.2934 0.7793 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O08 compound treatment 553421.0 35300.0 0.21 564486.0 38600.0 0.22 0.3039 0.9998 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O09 compound treatment 536307.0 18200.0 0.11 588428.0 62500.0 0.36 0.3281 0.8827 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O10 compound treatment 452515.0 -65600.0 -0.39 594200.0 68300.0 0.39 -0.0013 -0.0023 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O11 mock treatment 569879.0 51800.0 0.31 602011.0 76100.0 0.43 0.524 0.9862 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O12 mock treatment 541126.0 23100.0 0.14 514326.0 -11600.0 -0.07 0.0504 0.3314 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O13 compound treatment 499061.0 -19000.0 -0.11 487020.0 -38900.0 -0.22 -0.2364 -0.9516 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O14 compound treatment 485041.0 -33000.0 -0.2 565675.0 39800.0 0.23 0.0209 0.0697 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O15 compound treatment 191680.0 -326000.0 -1.94 168483.0 -357000.0 -2.03 -2.8108 -0.9997 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O16 compound treatment 497090.0 -21000.0 -0.12 574061.0 48200.0 0.27 0.1053 0.3499 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O17 compound treatment 541095.0 23000.0 0.14 486473.0 -39400.0 -0.22 -0.0617 -0.2348 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O18 compound treatment 477354.0 -40700.0 -0.24 510500.0 -15400.0 -0.09 -0.2333 -0.9054 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O19 compound treatment 527824.0 9750.0 0.06 538911.0 13000.0 0.07 0.0933 0.9928 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O20 compound treatment 583598.0 65500.0 0.39 568749.0 42800.0 0.24 0.448 0.9744 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O21 compound treatment 415721.0 -102000.0 -0.61 447409.0 -78500.0 -0.45 -0.7464 -0.9883 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O22 compound treatment 502632.0 -15400.0 -0.09 488552.0 -37400.0 -0.21 -0.2152 -0.9297 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O23 compound treatment 532998.0 14900.0 0.09 520274.0 -5630.0 -0.03 0.0402 0.4252 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 O24 compound treatment 442179.0 -75900.0 -0.45 555316.0 29400.0 0.17 -0.2011 -0.4176 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P01 compound treatment 455743.0 -62300.0 -0.37 504714.0 -21200.0 -0.12 -0.3475 -0.891 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P02 compound treatment 582583.0 64500.0 0.38 524540.0 -1370.0 -0.01 0.266 0.6926 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P03 compound treatment 423828.0 -94200.0 -0.56 397447.0 -128000.0 -0.73 -0.9132 -0.9915 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P04 compound treatment 542883.0 24800.0 0.15 511290.0 -14600.0 -0.08 0.0456 0.2693 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P05 compound treatment 57031.0 -461000.0 -2.74 52790.0 -473000.0 -2.69 -3.8427 -1.0 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P06 compound treatment 517486.0 -588.0 0.0 546692.0 20800.0 0.12 0.0811 0.6859 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P07 compound treatment 560672.0 42600.0 0.25 564024.0 38100.0 0.22 0.3325 0.997 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P08 compound treatment 493761.0 -24300.0 -0.14 521352.0 -4560.0 -0.03 -0.1206 -0.8207 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P09 compound treatment 550290.0 32200.0 0.19 593186.0 67300.0 0.38 0.4061 0.949 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P10 compound treatment 489157.0 -28900.0 -0.17 629427.0 104000.0 0.59 0.2946 0.4803 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P11 mock treatment 517971.0 -103.0 0.0 516982.0 -8930.0 -0.05 -0.0363 -0.7156 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P12 mock treatment 532208.0 14100.0 0.08 617217.0 91300.0 0.52 0.4266 0.8111 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P13 compound treatment 596279.0 78200.0 0.47 539718.0 13800.0 0.08 0.3846 0.8149 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P14 compound treatment 307128.0 -211000.0 -1.26 455841.0 -70100.0 -0.4 -1.1695 -0.8879 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P15 compound treatment 641271.0 123000.0 0.73 540966.0 15100.0 0.09 0.579 0.7844 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P16 compound treatment 433579.0 -84500.0 -0.5 567017.0 41100.0 0.23 -0.1903 -0.3431 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P17 compound treatment 593050.0 75000.0 0.45 591145.0 65200.0 0.37 0.5778 0.9958 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P18 compound treatment 626387.0 108000.0 0.64 536437.0 10500.0 0.06 0.4982 0.7695 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P19 compound treatment 199087.0 -319000.0 -1.9 194004.0 -332000.0 -1.89 -2.677 -1.0 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P20 compound treatment 235408.0 -283000.0 -1.68 241968.0 -284000.0 -1.61 -2.3313 -0.9998 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P21 compound treatment 269481.0 -249000.0 -1.48 198517.0 -327000.0 -1.86 -2.3626 -0.9935 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P22 compound treatment 236185.0 -282000.0 -1.68 227204.0 -299000.0 -1.7 -2.3874 -1.0 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P23 compound treatment 397105.0 -121000.0 -0.72 436904.0 -89000.0 -0.51 -0.867 -0.9851 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2095 P24 compound treatment 219549.0 -299000.0 -1.78 209933.0 -316000.0 -1.8 -2.5269 -1.0 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A01 compound treatment 273606.0 -151000.0 -0.9 153507.0 -322000.0 -1.83 -1.9316 -0.9462 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A02 compound treatment 491244.0 66600.0 0.4 500639.0 24800.0 0.14 0.3801 0.9034 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A03 compound treatment 231066.0 -194000.0 -1.15 105069.0 -371000.0 -2.11 -2.3054 -0.9596 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A04 compound treatment 510378.0 85700.0 0.51 550598.0 74800.0 0.43 0.6615 0.9959 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A05 compound treatment 506609.0 82000.0 0.49 579566.0 104000.0 0.59 0.7622 0.9955 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A06 compound treatment 183172.0 -241000.0 -1.44 137898.0 -338000.0 -1.92 -2.375 -0.9898 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A07 compound treatment 259237.0 -165000.0 -0.98 102305.0 -373000.0 -2.12 -2.198 -0.9389 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A08 compound treatment 331302.0 -93300.0 -0.56 392167.0 -83600.0 -0.48 -0.7291 -0.997 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A09 compound treatment 514116.0 89500.0 0.53 458228.0 -17600.0 -0.1 0.3058 0.5645 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A10 compound treatment 424100.0 -548.0 0.0 506844.0 31000.0 0.18 0.1225 0.6939 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A11 compound treatment 434635.0 9990.0 0.06 481427.0 5630.0 0.03 0.0646 0.9578 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A12 compound treatment 484821.0 60200.0 0.36 460196.0 -15600.0 -0.09 0.1905 0.5163 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A13 mock treatment 468793.0 44100.0 0.26 601549.0 126000.0 0.72 0.6914 0.9076 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A14 mock treatment 436869.0 12200.0 0.07 442311.0 -33500.0 -0.19 -0.0832 -0.4083 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A15 compound treatment 512323.0 87700.0 0.52 520689.0 44900.0 0.26 0.5495 0.9459 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A16 compound treatment 214202.0 -210000.0 -1.25 124550.0 -351000.0 -2.0 -2.2981 -0.9747 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A17 compound treatment 322185.0 -102000.0 -0.61 571005.0 95200.0 0.54 -0.0484 -0.0593 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A18 compound treatment 208431.0 -216000.0 -1.29 184920.0 -291000.0 -1.65 -2.0796 -0.9923 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A19 compound treatment 395323.0 -29300.0 -0.17 443306.0 -32500.0 -0.18 -0.2541 -0.9996 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A20 compound treatment 178158.0 -246000.0 -1.47 162081.0 -314000.0 -1.78 -2.2988 -0.9953 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A21 compound treatment 144205.0 -280000.0 -1.67 277606.0 -198000.0 -1.13 -1.9772 -0.9817 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A22 compound treatment 434259.0 9610.0 0.06 522731.0 46900.0 0.27 0.2292 0.8396 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A23 compound treatment 456452.0 31800.0 0.19 597521.0 122000.0 0.69 0.6233 0.8686 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 A24 compound treatment 472288.0 47600.0 0.28 472945.0 -2860.0 -0.02 0.189 0.6655 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B01 compound treatment 209886.0 -215000.0 -1.28 585202.0 109000.0 0.62 -0.4639 -0.3263 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B02 compound treatment 463879.0 39200.0 0.23 503602.0 27800.0 0.16 0.2769 0.982 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B03 compound treatment 489041.0 64400.0 0.38 553562.0 77800.0 0.44 0.5837 0.9975 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B04 compound treatment 196124.0 -229000.0 -1.36 133831.0 -342000.0 -1.94 -2.3368 -0.9847 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B05 compound treatment 474735.0 50100.0 0.3 581369.0 106000.0 0.6 0.6353 0.9478 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B06 compound treatment 540317.0 116000.0 0.69 517189.0 41400.0 0.24 0.6532 0.8978 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B07 compound treatment 567062.0 142000.0 0.85 535331.0 59500.0 0.34 0.8387 0.9189 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B08 compound treatment 497491.0 72800.0 0.43 484921.0 9120.0 0.05 0.3432 0.7861 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B09 compound treatment 577599.0 153000.0 0.91 585943.0 110000.0 0.63 1.0866 0.9834 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B10 compound treatment 481653.0 57000.0 0.34 509459.0 33700.0 0.19 0.3752 0.9633 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B11 compound treatment 436402.0 11800.0 0.07 468917.0 -6880.0 -0.04 0.0218 0.2717 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B12 compound treatment 60717.0 -364000.0 -2.17 69112.0 -407000.0 -2.31 -3.1669 -0.9995 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B13 mock treatment 472185.0 47500.0 0.28 476799.0 997.0 0.01 0.2041 0.7211 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B14 mock treatment 403775.0 -20900.0 -0.12 491867.0 16100.0 0.09 -0.0232 -0.1507 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B15 compound treatment 398543.0 -26100.0 -0.16 245404.0 -230000.0 -1.31 -1.0363 -0.7855 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B16 compound treatment 449791.0 25100.0 0.15 509370.0 33600.0 0.19 0.2408 0.9927 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B17 compound treatment 453157.0 28500.0 0.17 425308.0 -50500.0 -0.29 -0.0831 -0.2491 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B18 compound treatment 69432.0 -355000.0 -2.11 64127.0 -412000.0 -2.34 -3.1503 -0.9987 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B19 compound treatment 595707.0 171000.0 1.02 512937.0 37100.0 0.21 0.8692 0.836 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B20 compound treatment 414666.0 -9980.0 -0.06 384280.0 -91500.0 -0.52 -0.41 -0.7827 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B21 compound treatment 524160.0 99500.0 0.59 463561.0 -12200.0 -0.07 0.3696 0.6197 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B22 compound treatment 378647.0 -46000.0 -0.27 279933.0 -196000.0 -1.11 -0.9812 -0.8554 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B23 compound treatment 370401.0 -54200.0 -0.32 458561.0 -17200.0 -0.1 -0.2976 -0.8821 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 B24 compound treatment 390528.0 -34100.0 -0.2 382956.0 -92800.0 -0.53 -0.5169 -0.9138 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C01 compound treatment 283517.0 -141000.0 -0.84 231472.0 -244000.0 -1.39 -1.5764 -0.9709 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C02 compound treatment 436157.0 11500.0 0.07 327964.0 -148000.0 -0.84 -0.546 -0.6474 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C03 compound treatment 303259.0 -121000.0 -0.72 340295.0 -136000.0 -0.77 -1.0557 -0.9995 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C04 compound treatment 224269.0 -200000.0 -1.19 256481.0 -219000.0 -1.25 -1.7252 -0.9997 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C05 compound treatment 44770.0 -380000.0 -2.26 165121.0 -311000.0 -1.77 -2.8479 -0.9926 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C06 compound treatment 500644.0 76000.0 0.45 391673.0 -84100.0 -0.48 -0.0185 -0.0281 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C07 compound treatment 199918.0 -225000.0 -1.34 229621.0 -246000.0 -1.4 -1.9357 -0.9997 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C08 compound treatment 492976.0 68300.0 0.41 534804.0 59000.0 0.34 0.5248 0.9954 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C09 compound treatment 22535.0 -402000.0 -2.39 61765.0 -414000.0 -2.35 -3.3571 -1.0 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C10 compound treatment 250839.0 -174000.0 -1.03 473371.0 -2430.0 -0.01 -0.7412 -0.7165 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C11 mock treatment 362749.0 -61900.0 -0.37 411497.0 -64300.0 -0.37 -0.5191 -1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C12 mock treatment 456552.0 31900.0 0.19 492768.0 17000.0 0.1 0.2025 0.9507 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C13 compound treatment 409498.0 -15200.0 -0.09 476676.0 874.0 0.0 -0.0602 -0.6671 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C14 compound treatment 434155.0 9510.0 0.06 449970.0 -25800.0 -0.15 -0.0639 -0.4057 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C15 mock treatment 296010.0 -129000.0 -0.77 414326.0 -61500.0 -0.35 -0.7886 -0.9369 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C16 mock treatment 362236.0 -62400.0 -0.37 529399.0 53600.0 0.3 -0.0471 -0.0981 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C17 compound treatment 219371.0 -205000.0 -1.22 225857.0 -250000.0 -1.42 -1.8689 -0.9972 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C18 compound treatment 238229.0 -186000.0 -1.11 448364.0 -27400.0 -0.16 -0.8948 -0.7987 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C19 compound treatment 476400.0 51800.0 0.31 499821.0 24000.0 0.14 0.3144 0.9331 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C20 compound treatment 313872.0 -111000.0 -0.66 503663.0 27900.0 0.16 -0.3541 -0.5223 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C21 compound treatment 283344.0 -141000.0 -0.84 268697.0 -207000.0 -1.18 -1.4274 -0.9864 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C22 compound treatment 470987.0 46300.0 0.28 459368.0 -16400.0 -0.09 0.1289 0.4428 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C23 compound treatment 156289.0 -268000.0 -1.6 200322.0 -275000.0 -1.57 -2.2371 -1.0 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 C24 compound treatment 312592.0 -112000.0 -0.67 491090.0 15300.0 0.09 -0.4101 -0.6098 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D01 compound treatment 531831.0 107000.0 0.64 422986.0 -52800.0 -0.3 0.2387 0.3385 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D02 compound treatment 63949.0 -361000.0 -2.15 66768.0 -409000.0 -2.33 -3.1627 -0.9992 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D03 compound treatment 453772.0 29100.0 0.17 463539.0 -12300.0 -0.07 0.0732 0.3921 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D04 compound treatment 58826.0 -366000.0 -2.18 68750.0 -407000.0 -2.31 -3.1763 -0.9995 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D05 compound treatment 396325.0 -28300.0 -0.17 428332.0 -47500.0 -0.27 -0.3101 -0.9743 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D06 compound treatment 415212.0 -9440.0 -0.06 413654.0 -62100.0 -0.35 -0.2896 -0.8093 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D07 compound treatment 518093.0 93400.0 0.56 513636.0 37800.0 0.22 0.5454 0.9146 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D08 compound treatment 382253.0 -42400.0 -0.25 586249.0 110000.0 0.63 0.2657 0.3926 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D09 compound treatment 173398.0 -251000.0 -1.5 226019.0 -250000.0 -1.42 -2.0617 -0.9997 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D10 compound treatment 157162.0 -267000.0 -1.59 455558.0 -20200.0 -0.12 -1.2071 -0.7563 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D11 mock treatment 401978.0 -22700.0 -0.13 390703.0 -85100.0 -0.48 -0.4376 -0.871 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D12 mock treatment 422086.0 -2560.0 -0.02 445683.0 -30100.0 -0.17 -0.1319 -0.767 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D13 compound treatment 214921.0 -210000.0 -1.25 462141.0 -13700.0 -0.08 -0.9375 -0.7497 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D14 compound treatment 386413.0 -38200.0 -0.23 387281.0 -88500.0 -0.5 -0.5169 -0.9356 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D15 mock treatment 363537.0 -61100.0 -0.36 536802.0 61000.0 0.35 -0.0119 -0.0236 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D16 mock treatment 390679.0 -34000.0 -0.2 442088.0 -33700.0 -0.19 -0.2785 -0.9996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D17 compound treatment 485894.0 61200.0 0.36 562809.0 87000.0 0.49 0.6076 0.9887 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D18 compound treatment 350167.0 -74500.0 -0.44 503742.0 27900.0 0.16 -0.2011 -0.427 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D19 compound treatment 176334.0 -248000.0 -1.48 478346.0 2540.0 0.01 -1.0347 -0.7002 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D20 compound treatment 392518.0 -32100.0 -0.19 351958.0 -124000.0 -0.7 -0.6332 -0.8677 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D21 compound treatment 246951.0 -178000.0 -1.06 526913.0 51100.0 0.29 -0.5423 -0.4944 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D22 compound treatment 300541.0 -124000.0 -0.74 393630.0 -82200.0 -0.47 -0.8527 -0.9756 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D23 compound treatment 180636.0 -244000.0 -1.45 700234.0 224000.0 1.28 -0.1244 -0.0643 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 D24 compound treatment 151054.0 -274000.0 -1.63 109532.0 -366000.0 -2.08 -2.6242 -0.9926 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E01 mock treatment 517588.0 92900.0 0.55 548377.0 72600.0 0.41 0.683 0.9896 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E02 mock treatment 470126.0 45500.0 0.27 361076.0 -115000.0 -0.65 -0.2699 -0.3822 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E03 compound treatment 206824.0 -218000.0 -1.3 102164.0 -374000.0 -2.12 -2.4191 -0.9719 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E04 compound treatment 196234.0 -228000.0 -1.36 199232.0 -277000.0 -1.57 -2.0734 -0.9974 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E05 compound treatment 506066.0 81400.0 0.48 276777.0 -199000.0 -1.13 -0.4577 -0.3717 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E06 compound treatment 344055.0 -80600.0 -0.48 524211.0 48400.0 0.28 -0.1445 -0.2613 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E07 compound treatment 487303.0 62700.0 0.37 513064.0 37300.0 0.21 0.4135 0.9641 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E08 compound treatment 252722.0 -172000.0 -1.02 486804.0 11000.0 0.06 -0.6793 -0.6626 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E09 mock treatment 511681.0 87000.0 0.52 501986.0 26200.0 0.15 0.4715 0.8749 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E10 mock treatment 426010.0 1360.0 0.01 470956.0 -4850.0 -0.03 -0.0138 -0.4789 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E11 compound treatment 247831.0 -177000.0 -1.05 72618.0 -403000.0 -2.29 -2.3654 -0.9376 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E12 compound treatment 517239.0 92600.0 0.55 518138.0 42300.0 0.24 0.5599 0.9311 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E13 compound treatment 144456.0 -280000.0 -1.67 113601.0 -362000.0 -2.06 -2.6356 -0.9945 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E14 compound treatment 229385.0 -195000.0 -1.16 488994.0 13200.0 0.08 -0.7687 -0.6601 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E15 compound treatment 356554.0 -68100.0 -0.41 515889.0 40100.0 0.23 -0.1254 -0.2696 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E16 compound treatment 444748.0 20100.0 0.12 288923.0 -187000.0 -1.06 -0.6669 -0.6236 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E17 mock treatment 486084.0 61400.0 0.37 503505.0 27700.0 0.16 0.3699 0.9292 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E18 mock treatment 187519.0 -237000.0 -1.41 445457.0 -30300.0 -0.17 -1.1199 -0.7877 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E19 compound treatment 200572.0 -224000.0 -1.33 210355.0 -265000.0 -1.51 -2.0104 -0.9981 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E20 compound treatment 331444.0 -93200.0 -0.55 465028.0 -10800.0 -0.06 -0.4356 -0.7805 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E21 compound treatment 112240.0 -312000.0 -1.86 165537.0 -310000.0 -1.76 -2.5623 -0.9997 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E22 compound treatment 156497.0 -268000.0 -1.6 158042.0 -318000.0 -1.81 -2.4062 -0.9981 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E23 compound treatment 231610.0 -193000.0 -1.15 235427.0 -240000.0 -1.37 -1.7789 -0.9963 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 E24 compound treatment 49741.0 -375000.0 -2.23 60538.0 -415000.0 -2.36 -3.2476 -0.9996 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F01 mock treatment 525799.0 101000.0 0.6 316456.0 -159000.0 -0.91 -0.2151 -0.1977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F02 mock treatment 348906.0 -75700.0 -0.45 207519.0 -268000.0 -1.53 -1.3975 -0.8785 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F03 compound treatment 516401.0 91800.0 0.55 425553.0 -50200.0 -0.29 0.1841 0.2987 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F04 compound treatment 418212.0 -6440.0 -0.04 504294.0 28500.0 0.16 0.0875 0.5255 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F05 compound treatment 282751.0 -142000.0 -0.84 341088.0 -135000.0 -0.77 -1.1388 -0.9988 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F06 compound treatment 244321.0 -180000.0 -1.07 194980.0 -281000.0 -1.6 -1.8881 -0.9813 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F07 compound treatment 475449.0 50800.0 0.3 266277.0 -210000.0 -1.19 -0.6287 -0.5115 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F08 compound treatment 412477.0 -12200.0 -0.07 463797.0 -12000.0 -0.07 -0.0995 -0.9996 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F09 mock treatment 424413.0 -235.0 0.0 471391.0 -4410.0 -0.03 -0.0187 -0.7454 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F10 mock treatment 184513.0 -240000.0 -1.43 350068.0 -126000.0 -0.72 -1.5162 -0.9488 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F11 compound treatment 430139.0 5490.0 0.03 284103.0 -192000.0 -1.09 -0.7477 -0.6856 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F12 compound treatment 278941.0 -146000.0 -0.87 223753.0 -252000.0 -1.43 -1.6267 -0.971 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F13 compound treatment 345845.0 -78800.0 -0.47 430197.0 -45600.0 -0.26 -0.515 -0.961 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F14 compound treatment 483152.0 58500.0 0.35 500952.0 25200.0 0.14 0.3473 0.9228 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F15 compound treatment 220852.0 -204000.0 -1.21 168094.0 -308000.0 -1.75 -2.095 -0.984 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F16 compound treatment 75682.0 -349000.0 -2.08 97734.0 -378000.0 -2.15 -2.9888 -0.9999 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F17 mock treatment 175319.0 -249000.0 -1.48 494398.0 18600.0 0.11 -0.9745 -0.6551 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F18 mock treatment 162575.0 -262000.0 -1.56 424535.0 -51300.0 -0.29 -1.309 -0.825 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F19 compound treatment 187956.0 -237000.0 -1.41 172760.0 -303000.0 -1.72 -2.2146 -0.995 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F20 compound treatment 253877.0 -171000.0 -1.02 340075.0 -136000.0 -0.77 -1.2644 -0.9908 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F21 compound treatment 130788.0 -294000.0 -1.75 225429.0 -250000.0 -1.42 -2.2434 -0.9948 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F22 compound treatment 294825.0 -130000.0 -0.77 504950.0 29100.0 0.17 -0.4291 -0.543 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F23 compound treatment 524538.0 99900.0 0.59 504139.0 28300.0 0.16 0.5343 0.8675 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 F24 compound treatment 535533.0 111000.0 0.66 569554.0 93800.0 0.53 0.8436 0.9944 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G01 compound treatment 301054.0 -124000.0 -0.74 596765.0 121000.0 0.69 -0.0337 -0.0335 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G02 compound treatment 465784.0 41100.0 0.24 350351.0 -125000.0 -0.71 -0.3313 -0.4393 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G03 mock treatment 443363.0 18700.0 0.11 532361.0 56600.0 0.32 0.3062 0.8996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G04 mock treatment 453618.0 29000.0 0.17 480522.0 4720.0 0.03 0.1409 0.8075 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G05 compound treatment 187881.0 -237000.0 -1.41 190735.0 -285000.0 -1.62 -2.1427 -0.9976 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G06 compound treatment 162761.0 -262000.0 -1.56 119663.0 -356000.0 -2.03 -2.5342 -0.9916 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G07 compound treatment 211216.0 -213000.0 -1.27 241647.0 -234000.0 -1.33 -1.8398 -0.9997 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G08 compound treatment 198485.0 -226000.0 -1.35 80973.0 -395000.0 -2.25 -2.5394 -0.97 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G09 compound treatment 446916.0 22300.0 0.13 595153.0 119000.0 0.68 0.5736 0.8295 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G10 compound treatment 472467.0 47800.0 0.28 475317.0 -485.0 0.0 0.1993 0.7002 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G11 compound treatment 178487.0 -246000.0 -1.47 198296.0 -278000.0 -1.58 -2.1518 -0.9993 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G12 compound treatment 492270.0 67600.0 0.4 508204.0 32400.0 0.18 0.4149 0.9373 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G13 compound treatment 298277.0 -126000.0 -0.75 559925.0 84100.0 0.48 -0.1935 -0.2171 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G14 compound treatment 207432.0 -217000.0 -1.29 315774.0 -160000.0 -0.91 -1.5576 -0.9852 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G15 compound treatment 247909.0 -177000.0 -1.05 262823.0 -213000.0 -1.21 -1.6002 -0.9975 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G16 compound treatment 79499.0 -345000.0 -2.05 162226.0 -314000.0 -1.78 -2.7134 -0.9975 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G17 compound treatment 460873.0 36200.0 0.22 514702.0 38900.0 0.22 0.3089 0.9999 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G18 compound treatment 112595.0 -312000.0 -1.86 124995.0 -351000.0 -1.99 -2.7239 -0.9994 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G19 mock treatment 171912.0 -253000.0 -1.5 202599.0 -273000.0 -1.55 -2.1622 -0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G20 mock treatment 339545.0 -85100.0 -0.51 213142.0 -263000.0 -1.49 -1.4143 -0.8967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G21 compound treatment 180447.0 -244000.0 -1.45 137594.0 -338000.0 -1.92 -2.3877 -0.9905 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G22 compound treatment 372026.0 -52600.0 -0.31 118168.0 -358000.0 -2.03 -1.6595 -0.8065 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G23 compound treatment 102094.0 -323000.0 -1.92 137144.0 -339000.0 -1.93 -2.7192 -1.0 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 G24 compound treatment 232598.0 -192000.0 -1.14 591382.0 116000.0 0.66 -0.3434 -0.2605 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H01 compound treatment 545619.0 121000.0 0.72 367897.0 -108000.0 -0.61 0.0752 0.0795 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H02 compound treatment 107251.0 -317000.0 -1.89 248136.0 -228000.0 -1.29 -2.2512 -0.983 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H03 mock treatment 377873.0 -46800.0 -0.28 253898.0 -222000.0 -1.26 -1.0892 -0.8428 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H04 mock treatment 255764.0 -169000.0 -1.01 271561.0 -204000.0 -1.16 -1.532 -0.9974 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H05 compound treatment 476823.0 52200.0 0.31 293304.0 -182000.0 -1.04 -0.5143 -0.4747 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H06 compound treatment 344723.0 -79900.0 -0.48 676265.0 200000.0 1.14 0.4697 0.3803 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H07 compound treatment 78612.0 -346000.0 -2.06 140574.0 -335000.0 -1.91 -2.8042 -0.9993 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H08 compound treatment 386514.0 -38100.0 -0.23 446503.0 -29300.0 -0.17 -0.2783 -0.9885 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H09 compound treatment 432318.0 7670.0 0.05 440591.0 -35200.0 -0.2 -0.1093 -0.5323 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H10 compound treatment 63815.0 -361000.0 -2.15 62678.0 -413000.0 -2.35 -3.1797 -0.999 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H11 compound treatment 358021.0 -66600.0 -0.4 427298.0 -48500.0 -0.28 -0.4754 -0.9843 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H12 compound treatment 384868.0 -39800.0 -0.24 440352.0 -35400.0 -0.2 -0.31 -0.9968 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H13 compound treatment 263675.0 -161000.0 -0.96 296379.0 -179000.0 -1.02 -1.3989 -0.9995 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H14 compound treatment 368029.0 -56600.0 -0.34 377235.0 -98600.0 -0.56 -0.6346 -0.9703 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H15 compound treatment 126354.0 -298000.0 -1.78 451635.0 -24200.0 -0.14 -1.3525 -0.7596 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H16 compound treatment 22400.0 -402000.0 -2.39 84407.0 -391000.0 -2.23 -3.2666 -0.9993 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H17 compound treatment 187775.0 -237000.0 -1.41 178882.0 -297000.0 -1.69 -2.1908 -0.996 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H18 compound treatment 35854.0 -389000.0 -2.31 57662.0 -418000.0 -2.38 -3.3176 -0.9999 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H19 mock treatment 123738.0 -301000.0 -1.79 313299.0 -163000.0 -0.92 -1.9198 -0.9526 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H20 mock treatment 404839.0 -19800.0 -0.12 353887.0 -122000.0 -0.69 -0.5736 -0.8156 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H21 compound treatment 51307.0 -373000.0 -2.22 54326.0 -421000.0 -2.4 -3.2659 -0.9993 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H22 compound treatment 459239.0 34600.0 0.21 538954.0 63200.0 0.36 0.3995 0.9651 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H23 compound treatment 56979.0 -368000.0 -2.19 121381.0 -354000.0 -2.02 -2.9724 -0.9992 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 H24 compound treatment 456052.0 31400.0 0.19 458739.0 -17100.0 -0.1 0.0635 0.3017 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I01 compound treatment 194362.0 -230000.0 -1.37 193442.0 -282000.0 -1.61 -2.1045 -0.9969 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I02 compound treatment 441867.0 17200.0 0.1 469350.0 -6450.0 -0.04 0.0465 0.4274 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I03 compound treatment 423201.0 -1450.0 -0.01 470138.0 -5660.0 -0.03 -0.0289 -0.8658 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I04 compound treatment 238397.0 -186000.0 -1.11 307069.0 -169000.0 -0.96 -1.4623 -0.9974 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I05 mock treatment 480455.0 55800.0 0.33 476958.0 1160.0 0.01 0.2395 0.721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I06 mock treatment 446745.0 22100.0 0.13 496303.0 20500.0 0.12 0.1754 0.9982 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I07 compound treatment 402584.0 -22100.0 -0.13 383488.0 -92300.0 -0.52 -0.4641 -0.8576 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I08 compound treatment 353534.0 -71100.0 -0.42 367014.0 -109000.0 -0.62 -0.7367 -0.9829 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I09 compound treatment 482177.0 57500.0 0.34 468191.0 -7610.0 -0.04 0.2115 0.6128 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I10 compound treatment 75562.0 -349000.0 -2.08 298019.0 -178000.0 -1.01 -2.1839 -0.9452 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I11 compound treatment 505447.0 80800.0 0.48 544713.0 68900.0 0.39 0.6171 0.9948 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I12 compound treatment 392595.0 -32100.0 -0.19 460558.0 -15200.0 -0.09 -0.1962 -0.9363 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I13 compound treatment 456826.0 32200.0 0.19 520986.0 45200.0 0.26 0.3171 0.9895 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I14 compound treatment 212122.0 -213000.0 -1.26 230874.0 -245000.0 -1.39 -1.8793 -0.9988 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I15 compound treatment 212047.0 -213000.0 -1.27 326393.0 -149000.0 -0.85 -1.4955 -0.9812 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I16 compound treatment 468054.0 43400.0 0.26 235593.0 -240000.0 -1.37 -0.7833 -0.5634 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I17 compound treatment 224005.0 -201000.0 -1.19 590102.0 114000.0 0.65 -0.3847 -0.283 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I18 compound treatment 308027.0 -117000.0 -0.69 202210.0 -274000.0 -1.56 -1.5909 -0.9338 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I19 compound treatment 198904.0 -226000.0 -1.34 53971.0 -422000.0 -2.4 -2.6462 -0.9625 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I20 compound treatment 257075.0 -168000.0 -1.0 268104.0 -208000.0 -1.18 -1.5404 -0.9965 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I21 mock treatment 445916.0 21300.0 0.13 483351.0 7550.0 0.04 0.1199 0.8968 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I22 mock treatment 427013.0 2360.0 0.01 519107.0 43300.0 0.25 0.1841 0.7463 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I23 compound treatment 605030.0 180000.0 1.07 220012.0 -256000.0 -1.45 -0.2695 -0.1491 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 I24 compound treatment 97623.0 -327000.0 -1.95 481790.0 5990.0 0.03 -1.3521 -0.6946 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J01 compound treatment 61283.0 -363000.0 -2.16 70230.0 -406000.0 -2.31 -3.16 -0.9995 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J02 compound treatment 402743.0 -21900.0 -0.13 368036.0 -108000.0 -0.61 -0.5255 -0.8388 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J03 compound treatment 207911.0 -217000.0 -1.29 75929.0 -400000.0 -2.27 -2.52 -0.9639 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J04 compound treatment 346853.0 -77800.0 -0.46 407485.0 -68300.0 -0.39 -0.6021 -0.9962 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J05 mock treatment 439868.0 15200.0 0.09 499191.0 23400.0 0.13 0.1581 0.9825 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J06 mock treatment 299696.0 -125000.0 -0.74 292367.0 -183000.0 -1.04 -1.2635 -0.9862 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J07 compound treatment 455818.0 31200.0 0.19 528227.0 52400.0 0.3 0.342 0.9739 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J08 compound treatment 125361.0 -299000.0 -1.78 231812.0 -244000.0 -1.39 -2.2406 -0.9924 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J09 compound treatment 457284.0 32600.0 0.19 561294.0 85500.0 0.49 0.4811 0.919 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J10 compound treatment 449813.0 25200.0 0.15 479450.0 3650.0 0.02 0.1206 0.7974 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J11 compound treatment 408885.0 -15800.0 -0.09 527819.0 52000.0 0.3 0.1428 0.4603 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J12 compound treatment 483605.0 59000.0 0.35 483524.0 7720.0 0.04 0.2792 0.7894 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J13 compound treatment 485998.0 61300.0 0.37 409458.0 -66300.0 -0.38 -0.0086 -0.0164 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J14 compound treatment 55800.0 -369000.0 -2.2 57011.0 -419000.0 -2.38 -3.2362 -0.9992 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J15 compound treatment 254713.0 -170000.0 -1.01 428383.0 -47400.0 -0.27 -0.9058 -0.8654 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J16 compound treatment 40262.0 -384000.0 -2.29 64236.0 -412000.0 -2.34 -3.2726 -0.9999 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J17 compound treatment 412897.0 -11800.0 -0.07 481452.0 5650.0 0.03 -0.0267 -0.3473 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J18 compound treatment 61205.0 -363000.0 -2.16 63074.0 -413000.0 -2.35 -3.1891 -0.9992 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J19 compound treatment 214742.0 -210000.0 -1.25 199483.0 -276000.0 -1.57 -1.9945 -0.9935 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J20 compound treatment 53857.0 -371000.0 -2.21 62520.0 -413000.0 -2.35 -3.2223 -0.9995 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J21 mock treatment 460971.0 36300.0 0.22 484564.0 8760.0 0.05 0.1881 0.8479 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J22 mock treatment 442110.0 17500.0 0.1 429222.0 -46600.0 -0.26 -0.1138 -0.4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J23 compound treatment 597564.0 173000.0 1.03 616716.0 141000.0 0.8 1.2943 0.9923 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 J24 compound treatment 503501.0 78900.0 0.47 447057.0 -28700.0 -0.16 0.2162 0.4352 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K01 compound treatment 583769.0 159000.0 0.95 520627.0 44800.0 0.25 0.8499 0.8666 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K02 compound treatment 448844.0 24200.0 0.14 432903.0 -42900.0 -0.24 -0.0707 -0.2495 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K03 compound treatment 435125.0 10500.0 0.06 355288.0 -121000.0 -0.69 -0.4405 -0.6401 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K04 compound treatment 532446.0 108000.0 0.64 500236.0 24400.0 0.14 0.5519 0.8408 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K05 compound treatment 543999.0 119000.0 0.71 518465.0 42700.0 0.24 0.6738 0.8977 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K06 compound treatment 482327.0 57700.0 0.34 487763.0 12000.0 0.07 0.2908 0.8311 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K07 mock treatment 593471.0 169000.0 1.0 517625.0 41800.0 0.24 0.8786 0.851 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K08 mock treatment 449643.0 25000.0 0.15 467363.0 -8440.0 -0.05 0.0713 0.4559 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K09 compound treatment 451112.0 26500.0 0.16 427481.0 -48300.0 -0.27 -0.0829 -0.2619 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K10 compound treatment 535859.0 111000.0 0.66 555835.0 80000.0 0.46 0.7898 0.9833 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K11 compound treatment 517544.0 92900.0 0.55 477297.0 1500.0 0.01 0.3969 0.7179 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K12 compound treatment 517348.0 92700.0 0.55 556501.0 80700.0 0.46 0.7146 0.9958 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K13 compound treatment 469738.0 45100.0 0.27 572721.0 96900.0 0.55 0.5795 0.9453 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K14 compound treatment 506998.0 82300.0 0.49 593390.0 118000.0 0.67 0.8194 0.9883 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K15 mock treatment 496085.0 71400.0 0.43 548281.0 72500.0 0.41 0.5921 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K16 mock treatment 446276.0 21600.0 0.13 509052.0 33300.0 0.19 0.2247 0.9824 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K17 compound treatment 504144.0 79500.0 0.47 490877.0 15100.0 0.09 0.3952 0.8219 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K18 compound treatment 455172.0 30500.0 0.18 405292.0 -70500.0 -0.4 -0.1551 -0.3523 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K19 compound treatment 162285.0 -262000.0 -1.56 150518.0 -325000.0 -1.85 -2.4121 -0.9964 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K20 compound treatment 463058.0 38400.0 0.23 483153.0 7350.0 0.04 0.1912 0.8228 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K21 compound treatment 503357.0 78700.0 0.47 395854.0 -79900.0 -0.45 0.0097 0.0149 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K22 compound treatment 464792.0 40100.0 0.24 497742.0 21900.0 0.12 0.2572 0.9541 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K23 mock treatment 565628.0 141000.0 0.84 614836.0 139000.0 0.79 1.1524 0.9996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 K24 mock treatment 517698.0 93000.0 0.55 547249.0 71400.0 0.41 0.6789 0.9884 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L01 compound treatment 523671.0 99000.0 0.59 553387.0 77600.0 0.44 0.7287 0.9898 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L02 compound treatment 61660.0 -363000.0 -2.16 67925.0 -408000.0 -2.32 -3.1677 -0.9994 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L03 compound treatment 479933.0 55300.0 0.33 503632.0 27800.0 0.16 0.3446 0.9437 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L04 compound treatment 434180.0 9530.0 0.06 501024.0 25200.0 0.14 0.1415 0.9176 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L05 compound treatment 500839.0 76200.0 0.45 321282.0 -155000.0 -0.88 -0.3007 -0.3041 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L06 compound treatment 486883.0 62200.0 0.37 511291.0 35500.0 0.2 0.4046 0.9592 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L07 mock treatment 493224.0 68600.0 0.41 570096.0 94300.0 0.54 0.6678 0.9909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L08 mock treatment 308133.0 -117000.0 -0.69 410386.0 -65400.0 -0.37 -0.7534 -0.9574 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L09 compound treatment 67217.0 -357000.0 -2.13 75786.0 -400000.0 -2.27 -3.1127 -0.9994 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L10 compound treatment 348769.0 -75900.0 -0.45 359980.0 -116000.0 -0.66 -0.7851 -0.983 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L11 compound treatment 405116.0 -19500.0 -0.12 467729.0 -8070.0 -0.05 -0.1147 -0.9174 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L12 compound treatment 181331.0 -243000.0 -1.45 472618.0 -3180.0 -0.02 -1.0368 -0.7159 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L13 compound treatment 459745.0 35100.0 0.21 474466.0 -1340.0 -0.01 0.1423 0.6809 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L14 compound treatment 98071.0 -327000.0 -1.94 148331.0 -327000.0 -1.86 -2.6911 -0.9998 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L15 mock treatment 263516.0 -161000.0 -0.96 491467.0 15700.0 0.09 -0.6151 -0.6387 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L16 mock treatment 441681.0 17000.0 0.1 465015.0 -10800.0 -0.06 0.0283 0.2389 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L17 compound treatment 72087.0 -353000.0 -2.1 77103.0 -399000.0 -2.27 -3.0869 -0.9993 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L18 compound treatment 338234.0 -86400.0 -0.51 383392.0 -92400.0 -0.53 -0.7352 -0.9999 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L19 compound treatment 325556.0 -99100.0 -0.59 327071.0 -149000.0 -0.85 -1.0151 -0.9845 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L20 compound treatment 108955.0 -316000.0 -1.88 108667.0 -367000.0 -2.09 -2.8048 -0.9986 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L21 compound treatment 477781.0 53100.0 0.32 477762.0 1960.0 0.01 0.2315 0.7316 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L22 compound treatment 473796.0 49100.0 0.29 557011.0 81200.0 0.46 0.5334 0.9757 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L23 mock treatment 170945.0 -254000.0 -1.51 520547.0 44700.0 0.25 -0.8877 -0.5798 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 L24 mock treatment 379925.0 -44700.0 -0.27 391038.0 -84800.0 -0.48 -0.5291 -0.9608 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M01 compound treatment 404194.0 -20500.0 -0.12 424620.0 -51200.0 -0.29 -0.2919 -0.9252 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M02 compound treatment 321673.0 -103000.0 -0.61 240246.0 -236000.0 -1.34 -1.3806 -0.9372 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M03 compound treatment 499177.0 74500.0 0.44 517668.0 41900.0 0.24 0.482 0.9574 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M04 compound treatment 182148.0 -243000.0 -1.44 107889.0 -368000.0 -2.09 -2.4999 -0.9836 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M05 compound treatment 216935.0 -208000.0 -1.24 221156.0 -255000.0 -1.45 -1.8981 -0.9969 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M06 compound treatment 534733.0 110000.0 0.66 622338.0 147000.0 0.83 1.0525 0.9929 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M07 compound treatment 243912.0 -181000.0 -1.08 252848.0 -223000.0 -1.27 -1.6571 -0.9967 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M08 compound treatment 201524.0 -223000.0 -1.33 163519.0 -312000.0 -1.78 -2.1947 -0.9897 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M09 mock treatment 511674.0 87000.0 0.52 255537.0 -220000.0 -1.25 -0.5195 -0.3833 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M10 mock treatment 573050.0 148000.0 0.88 590194.0 114000.0 0.65 1.0845 0.9887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M11 compound treatment 439579.0 14900.0 0.09 504155.0 28400.0 0.16 0.1768 0.9606 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M12 compound treatment 592329.0 168000.0 1.0 569341.0 93500.0 0.53 1.0818 0.9566 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M13 mock treatment 541017.0 116000.0 0.69 468750.0 -7050.0 -0.04 0.4614 0.665 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M14 mock treatment 548074.0 123000.0 0.73 660646.0 185000.0 1.05 1.2627 0.9846 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M15 compound treatment 575742.0 151000.0 0.9 441006.0 -34800.0 -0.2 0.4959 0.5386 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M16 compound treatment 469447.0 44800.0 0.27 497590.0 21800.0 0.12 0.2761 0.9392 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M17 compound treatment 516621.0 92000.0 0.55 536327.0 60500.0 0.34 0.6304 0.975 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M18 compound treatment 524697.0 100000.0 0.6 386181.0 -89600.0 -0.51 0.0607 0.0774 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M19 compound treatment 171529.0 -253000.0 -1.51 184453.0 -291000.0 -1.66 -2.2368 -0.9989 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M20 compound treatment 380962.0 -43700.0 -0.26 464347.0 -11500.0 -0.07 -0.2299 -0.8578 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M21 compound treatment 448547.0 23900.0 0.14 444173.0 -31600.0 -0.18 -0.0266 -0.1161 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M22 compound treatment 198819.0 -226000.0 -1.34 189921.0 -286000.0 -1.63 -2.0999 -0.9955 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M23 compound treatment 211218.0 -213000.0 -1.27 234680.0 -241000.0 -1.37 -1.8678 -0.9993 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 M24 compound treatment 136691.0 -288000.0 -1.71 119268.0 -357000.0 -2.03 -2.6455 -0.9965 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N01 compound treatment 525368.0 101000.0 0.6 390857.0 -84900.0 -0.48 0.0823 0.1069 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N02 compound treatment 506321.0 81700.0 0.49 490557.0 14800.0 0.08 0.403 0.8171 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N03 compound treatment 264542.0 -160000.0 -0.95 519131.0 43300.0 0.25 -0.4995 -0.5076 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N04 compound treatment 509980.0 85300.0 0.51 537770.0 62000.0 0.35 0.6083 0.9841 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N05 compound treatment 499339.0 74700.0 0.44 368023.0 -108000.0 -0.61 -0.1191 -0.1573 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N06 compound treatment 505054.0 80400.0 0.48 561533.0 85700.0 0.49 0.6831 1.0 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N07 compound treatment 552964.0 128000.0 0.76 666129.0 190000.0 1.08 1.3053 0.9854 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N08 compound treatment 651946.0 227000.0 1.35 633277.0 157000.0 0.9 1.5898 0.9799 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N09 mock treatment 204489.0 -220000.0 -1.31 567416.0 91600.0 0.52 -0.5581 -0.3958 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N10 mock treatment 518180.0 93500.0 0.56 538806.0 63000.0 0.36 0.647 0.9773 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N11 compound treatment 552831.0 128000.0 0.76 644898.0 169000.0 0.96 1.2194 0.9934 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N12 compound treatment 516647.0 92000.0 0.55 566562.0 90800.0 0.52 0.7521 0.9996 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N13 mock treatment 548876.0 124000.0 0.74 525218.0 49400.0 0.28 0.7215 0.9122 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N14 mock treatment 504323.0 79700.0 0.47 576391.0 101000.0 0.57 0.7398 0.9957 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N15 compound treatment 520383.0 95700.0 0.57 479641.0 3840.0 0.02 0.4183 0.7337 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N16 compound treatment 283276.0 -141000.0 -0.84 126175.0 -350000.0 -1.99 -2.0008 -0.9268 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N17 compound treatment 470081.0 45400.0 0.27 396622.0 -79200.0 -0.45 -0.1272 -0.2422 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N18 compound treatment 514739.0 90100.0 0.54 568376.0 92600.0 0.53 0.7514 1.0 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N19 compound treatment 604076.0 179000.0 1.07 501371.0 25600.0 0.15 0.8579 0.796 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N20 compound treatment 58574.0 -366000.0 -2.18 62142.0 -414000.0 -2.35 -3.2039 -0.9993 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N21 compound treatment 282289.0 -142000.0 -0.85 281320.0 -194000.0 -1.11 -1.3811 -0.9913 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N22 compound treatment 512037.0 87400.0 0.52 552827.0 77000.0 0.44 0.6775 0.9964 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N23 compound treatment 331022.0 -93600.0 -0.56 354485.0 -121000.0 -0.69 -0.8818 -0.9944 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 N24 compound treatment 547596.0 123000.0 0.73 566065.0 90300.0 0.51 0.8804 0.985 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O01 compound treatment 556286.0 132000.0 0.78 571497.0 95700.0 0.54 0.9388 0.9841 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O02 compound treatment 485895.0 61200.0 0.36 533408.0 57600.0 0.33 0.4894 0.9986 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O03 compound treatment 80685.0 -344000.0 -2.05 72923.0 -403000.0 -2.29 -3.0675 -0.9984 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O04 compound treatment 580027.0 155000.0 0.92 595784.0 120000.0 0.68 1.1363 0.9888 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O05 compound treatment 258657.0 -166000.0 -0.99 261392.0 -214000.0 -1.22 -1.5607 -0.9945 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O06 compound treatment 520803.0 96200.0 0.57 565913.0 90100.0 0.51 0.767 0.9985 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O07 compound treatment 281164.0 -143000.0 -0.85 275620.0 -200000.0 -1.14 -1.4088 -0.99 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O08 compound treatment 233786.0 -191000.0 -1.14 253748.0 -222000.0 -1.26 -1.6961 -0.9986 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O09 compound treatment 592199.0 168000.0 1.0 625119.0 149000.0 0.85 1.3055 0.9968 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O10 compound treatment 564623.0 140000.0 0.83 592669.0 117000.0 0.66 1.059 0.9937 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O11 mock treatment 292498.0 -132000.0 -0.79 696567.0 221000.0 1.26 0.3316 0.2238 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O12 mock treatment 595985.0 171000.0 1.02 692900.0 217000.0 1.23 1.594 0.9955 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O13 compound treatment 637568.0 213000.0 1.27 713715.0 238000.0 1.35 1.8527 0.9995 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O14 compound treatment 488812.0 64200.0 0.38 572029.0 96200.0 0.55 0.657 0.9845 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O15 compound treatment 605730.0 181000.0 1.08 658477.0 183000.0 1.04 1.4966 0.9998 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O16 compound treatment 598115.0 173000.0 1.03 631013.0 155000.0 0.88 1.3541 0.997 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O17 compound treatment 215967.0 -209000.0 -1.24 213831.0 -262000.0 -1.49 -1.9316 -0.9959 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O18 compound treatment 263197.0 -161000.0 -0.96 240751.0 -235000.0 -1.34 -1.6246 -0.9869 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O19 compound treatment 217742.0 -207000.0 -1.23 196659.0 -279000.0 -1.59 -1.9932 -0.9921 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O20 compound treatment 494296.0 69600.0 0.41 572732.0 96900.0 0.55 0.6829 0.9901 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O21 compound treatment 458271.0 33600.0 0.2 476829.0 1030.0 0.01 0.1456 0.7274 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O22 compound treatment 497652.0 73000.0 0.43 609079.0 133000.0 0.76 0.8431 0.9651 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O23 compound treatment 501378.0 76700.0 0.46 609239.0 133000.0 0.76 0.8595 0.9705 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 O24 compound treatment 544142.0 119000.0 0.71 637186.0 161000.0 0.92 1.1518 0.9921 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P01 compound treatment 558245.0 134000.0 0.8 570451.0 94600.0 0.54 0.9428 0.9819 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P02 compound treatment 472144.0 47500.0 0.28 631872.0 156000.0 0.89 0.8275 0.8883 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P03 compound treatment 505498.0 80800.0 0.48 270582.0 -205000.0 -1.17 -0.485 -0.3842 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P04 compound treatment 540944.0 116000.0 0.69 331800.0 -144000.0 -0.82 -0.0896 -0.0836 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P05 compound treatment 553211.0 129000.0 0.77 556773.0 81000.0 0.46 0.8666 0.9705 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P06 compound treatment 65846.0 -359000.0 -2.14 70382.0 -405000.0 -2.31 -3.1402 -0.9993 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P07 compound treatment 458175.0 33500.0 0.2 612327.0 137000.0 0.78 0.6901 0.8609 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P08 compound treatment 505351.0 80700.0 0.48 597346.0 122000.0 0.69 0.8284 0.9842 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P09 compound treatment 511228.0 86600.0 0.52 601850.0 126000.0 0.72 0.8712 0.9869 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P10 compound treatment 540864.0 116000.0 0.69 489555.0 13800.0 0.08 0.5444 0.7821 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P11 mock treatment 525396.0 101000.0 0.6 655183.0 179000.0 1.02 1.1453 0.9679 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P12 mock treatment 599614.0 175000.0 1.04 555422.0 79600.0 0.45 1.0565 0.9304 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P13 compound treatment 61500.0 -363000.0 -2.16 68553.0 -407000.0 -2.32 -3.1658 -0.9994 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P14 compound treatment 590969.0 166000.0 0.99 612189.0 136000.0 0.78 1.2484 0.9927 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P15 compound treatment 392067.0 -32600.0 -0.19 447494.0 -28300.0 -0.16 -0.2509 -0.9957 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P16 compound treatment 533270.0 109000.0 0.65 620544.0 145000.0 0.82 1.0391 0.9929 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P17 compound treatment 52502.0 -372000.0 -2.21 62945.0 -413000.0 -2.35 -3.2263 -0.9996 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P18 compound treatment 432262.0 7610.0 0.05 371709.0 -104000.0 -0.59 -0.3865 -0.6511 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P19 compound treatment 49843.0 -375000.0 -2.23 70383.0 -405000.0 -2.31 -3.2075 -0.9999 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P20 compound treatment 520484.0 95800.0 0.57 536486.0 60700.0 0.35 0.6473 0.971 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P21 compound treatment 530515.0 106000.0 0.63 523522.0 47700.0 0.27 0.6374 0.9291 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P22 compound treatment 457484.0 32800.0 0.2 495466.0 19700.0 0.11 0.2173 0.9649 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P23 compound treatment 116755.0 -308000.0 -1.83 121126.0 -355000.0 -2.02 -2.7219 -0.9989 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2096 P24 compound treatment 590584.0 166000.0 0.99 567211.0 91400.0 0.52 1.0659 0.9551 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A01 compound treatment 565412.0 114000.0 0.68 537591.0 56700.0 0.32 0.7076 0.9421 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A02 compound treatment 460580.0 9170.0 0.05 483726.0 2800.0 0.02 0.0498 0.8767 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A03 compound treatment 93942.0 -357000.0 -2.13 83933.0 -397000.0 -2.26 -3.1007 -0.9996 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A04 compound treatment 512832.0 61400.0 0.37 497513.0 16600.0 0.09 0.3252 0.8613 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A05 compound treatment 330684.0 -121000.0 -0.72 515420.0 34500.0 0.2 -0.3694 -0.4959 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A06 compound treatment 56480.0 -395000.0 -2.35 75294.0 -406000.0 -2.31 -3.2931 -1.0 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A07 compound treatment 263982.0 -187000.0 -1.12 396188.0 -84700.0 -0.48 -1.1295 -0.9296 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A08 compound treatment 408457.0 -43000.0 -0.26 586269.0 105000.0 0.6 0.2428 0.3728 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A09 compound treatment 182690.0 -269000.0 -1.6 407604.0 -73300.0 -0.42 -1.4257 -0.8626 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A10 compound treatment 326976.0 -124000.0 -0.74 290103.0 -191000.0 -1.09 -1.291 -0.9826 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A11 compound treatment 129802.0 -322000.0 -1.91 487354.0 6420.0 0.04 -1.3276 -0.6935 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A12 compound treatment 135173.0 -316000.0 -1.88 162465.0 -318000.0 -1.81 -2.6114 -0.9998 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A13 mock treatment 459174.0 7760.0 0.05 556392.0 75500.0 0.43 0.3361 0.7787 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A14 mock treatment 460459.0 9050.0 0.05 517835.0 36900.0 0.21 0.1865 0.8607 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A15 compound treatment 81545.0 -370000.0 -2.2 79843.0 -401000.0 -2.28 -3.1693 -0.9998 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A16 compound treatment 298707.0 -153000.0 -0.91 479842.0 -1090.0 -0.01 -0.647 -0.7119 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A17 compound treatment 329116.0 -122000.0 -0.73 447082.0 -33800.0 -0.19 -0.6508 -0.8644 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A18 compound treatment 300285.0 -151000.0 -0.9 165642.0 -315000.0 -1.79 -1.9038 -0.9491 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A19 compound treatment 425366.0 -26000.0 -0.15 544752.0 63800.0 0.36 0.147 0.3726 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A20 compound treatment 104983.0 -346000.0 -2.06 286949.0 -194000.0 -1.1 -2.2379 -0.9571 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A21 compound treatment 441620.0 -9790.0 -0.06 480597.0 -333.0 0.0 -0.0425 -0.7297 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A22 compound treatment 170949.0 -280000.0 -1.67 454648.0 -26300.0 -0.15 -1.2859 -0.7674 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A23 compound treatment 44699.0 -407000.0 -2.42 72555.0 -408000.0 -2.32 -3.3537 -0.9998 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 A24 compound treatment 482067.0 30700.0 0.18 231784.0 -249000.0 -1.42 -0.8728 -0.611 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B01 compound treatment 418339.0 -33100.0 -0.2 520442.0 39500.0 0.22 0.0197 0.066 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B02 compound treatment 231120.0 -220000.0 -1.31 341984.0 -139000.0 -0.79 -1.4858 -0.9706 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B03 compound treatment 407997.0 -43400.0 -0.26 474229.0 -6700.0 -0.04 -0.2096 -0.8027 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B04 compound treatment 349354.0 -102000.0 -0.61 426547.0 -54400.0 -0.31 -0.6482 -0.951 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B05 compound treatment 332459.0 -119000.0 -0.71 547444.0 66500.0 0.38 -0.2331 -0.2904 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B06 compound treatment 242239.0 -209000.0 -1.24 420820.0 -60100.0 -0.34 -1.122 -0.8691 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B07 compound treatment 76558.0 -375000.0 -2.23 73774.0 -407000.0 -2.32 -3.2147 -0.9998 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B08 compound treatment 393585.0 -57800.0 -0.34 555527.0 74600.0 0.42 0.0566 0.1037 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B09 compound treatment 445439.0 -5970.0 -0.04 414810.0 -66100.0 -0.38 -0.291 -0.7705 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B10 compound treatment 461184.0 9770.0 0.06 353295.0 -128000.0 -0.73 -0.4721 -0.6484 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B11 compound treatment 174220.0 -277000.0 -1.65 419900.0 -61000.0 -0.35 -1.4119 -0.8375 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B12 compound treatment 457298.0 5890.0 0.04 341876.0 -139000.0 -0.79 -0.5344 -0.6751 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B13 mock treatment 169299.0 -282000.0 -1.68 468126.0 -12800.0 -0.07 -1.2387 -0.7371 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B14 mock treatment 530361.0 79000.0 0.47 406348.0 -74600.0 -0.42 0.0323 0.0511 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B15 compound treatment 471819.0 20400.0 0.12 469742.0 -11200.0 -0.06 0.0409 0.2983 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B16 compound treatment 180310.0 -271000.0 -1.61 318957.0 -162000.0 -0.92 -1.7922 -0.9647 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B17 compound treatment 156271.0 -295000.0 -1.76 438460.0 -42500.0 -0.24 -1.4128 -0.7968 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B18 compound treatment 43634.0 -408000.0 -2.43 57522.0 -423000.0 -2.41 -3.4186 -1.0 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B19 compound treatment 349325.0 -102000.0 -0.61 239049.0 -242000.0 -1.38 -1.4022 -0.9325 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B20 compound treatment 219493.0 -232000.0 -1.38 460069.0 -20900.0 -0.12 -1.0599 -0.7651 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B21 compound treatment 466524.0 15100.0 0.09 218193.0 -263000.0 -1.49 -0.9929 -0.6633 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B22 compound treatment 706295.0 255000.0 1.52 440708.0 -40200.0 -0.23 0.9109 0.5938 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B23 compound treatment 492499.0 41100.0 0.24 514061.0 33100.0 0.19 0.3061 0.9917 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 B24 compound treatment 41568.0 -410000.0 -2.44 175916.0 -305000.0 -1.73 -2.9512 -0.986 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C01 compound treatment 470150.0 18700.0 0.11 268712.0 -212000.0 -1.21 -0.7745 -0.639 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C02 compound treatment 391287.0 -60100.0 -0.36 480907.0 -22.6 0.0 -0.2531 -0.7074 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C03 compound treatment 103087.0 -348000.0 -2.07 137606.0 -343000.0 -1.95 -2.8464 -0.9996 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C04 compound treatment 491552.0 40100.0 0.24 252247.0 -229000.0 -1.3 -0.7506 -0.5677 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C05 compound treatment 493613.0 42200.0 0.25 494136.0 13200.0 0.08 0.2307 0.88 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C06 compound treatment 486988.0 35600.0 0.21 493774.0 12800.0 0.07 0.2014 0.899 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C07 compound treatment 188061.0 -263000.0 -1.57 336611.0 -144000.0 -0.82 -1.6886 -0.9544 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C08 compound treatment 319753.0 -132000.0 -0.78 345909.0 -135000.0 -0.77 -1.097 -0.9999 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C09 compound treatment 197048.0 -254000.0 -1.51 192238.0 -289000.0 -1.64 -2.2313 -0.9992 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C10 compound treatment 261661.0 -190000.0 -1.13 514459.0 33500.0 0.19 -0.6637 -0.5795 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C11 mock treatment 439872.0 -11500.0 -0.07 507786.0 26900.0 0.15 0.0594 0.355 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C12 mock treatment 436410.0 -15000.0 -0.09 444892.0 -36000.0 -0.2 -0.208 -0.9307 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C13 compound treatment 46234.0 -405000.0 -2.41 65301.0 -416000.0 -2.36 -3.3764 -0.9999 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C14 compound treatment 56215.0 -395000.0 -2.35 42520.0 -438000.0 -2.49 -3.426 -0.9996 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C15 mock treatment 252536.0 -199000.0 -1.18 480409.0 -521.0 0.0 -0.839 -0.7089 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C16 mock treatment 449097.0 -2310.0 -0.01 417007.0 -63900.0 -0.36 -0.2668 -0.7334 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C17 compound treatment 153549.0 -298000.0 -1.77 136374.0 -345000.0 -1.96 -2.639 -0.9988 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C18 compound treatment 391032.0 -60400.0 -0.36 452311.0 -28600.0 -0.16 -0.3692 -0.9359 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C19 compound treatment 463332.0 11900.0 0.07 459561.0 -21400.0 -0.12 -0.0358 -0.2541 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C20 compound treatment 53926.0 -397000.0 -2.37 57415.0 -424000.0 -2.41 -3.3757 -1.0 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C21 compound treatment 74134.0 -377000.0 -2.25 72749.0 -408000.0 -2.32 -3.229 -0.9999 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C22 compound treatment 391921.0 -59500.0 -0.35 456060.0 -24900.0 -0.14 -0.3504 -0.919 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C23 compound treatment 316476.0 -135000.0 -0.8 372885.0 -108000.0 -0.61 -1.0023 -0.9913 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 C24 compound treatment 486893.0 35500.0 0.21 547342.0 66400.0 0.38 0.4164 0.9623 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D01 compound treatment 353111.0 -98300.0 -0.59 531513.0 50600.0 0.29 -0.2103 -0.3225 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D02 compound treatment 425147.0 -26300.0 -0.16 541915.0 61000.0 0.35 0.1347 0.3541 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D03 compound treatment 492094.0 40700.0 0.24 509796.0 28900.0 0.16 0.2873 0.9821 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D04 compound treatment 335337.0 -116000.0 -0.69 460888.0 -20000.0 -0.11 -0.5691 -0.8128 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D05 compound treatment 543157.0 91700.0 0.55 469072.0 -11900.0 -0.07 0.3384 0.6151 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D06 compound treatment 304335.0 -147000.0 -0.88 349006.0 -132000.0 -0.75 -1.1494 -0.9971 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D07 compound treatment 492921.0 41500.0 0.25 479969.0 -961.0 -0.01 0.1708 0.6913 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D08 compound treatment 95800.0 -356000.0 -2.12 26569.0 -454000.0 -2.58 -3.3236 -0.9951 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D09 compound treatment 171930.0 -279000.0 -1.66 302695.0 -178000.0 -1.01 -1.8928 -0.9718 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D10 compound treatment 145969.0 -305000.0 -1.82 222496.0 -258000.0 -1.47 -2.3246 -0.9944 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D11 mock treatment 112560.0 -339000.0 -2.02 435539.0 -45400.0 -0.26 -1.6085 -0.7912 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D12 mock treatment 443656.0 -7750.0 -0.05 231907.0 -249000.0 -1.42 -1.034 -0.7298 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D13 compound treatment 506532.0 55100.0 0.33 424265.0 -56700.0 -0.32 0.0041 0.0089 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D14 compound treatment 150639.0 -301000.0 -1.79 350755.0 -130000.0 -0.74 -1.7892 -0.9237 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D15 mock treatment 362869.0 -88500.0 -0.53 497291.0 16400.0 0.09 -0.3068 -0.5734 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D16 mock treatment 408090.0 -43300.0 -0.26 448910.0 -32000.0 -0.18 -0.3111 -0.9855 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D17 compound treatment 83926.0 -367000.0 -2.19 125243.0 -356000.0 -2.02 -2.9767 -0.9992 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D18 compound treatment 130279.0 -321000.0 -1.91 191887.0 -289000.0 -1.64 -2.5137 -0.9972 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D19 compound treatment 518810.0 67400.0 0.4 473023.0 -7910.0 -0.04 0.2518 0.6239 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D20 compound treatment 322340.0 -129000.0 -0.77 342531.0 -138000.0 -0.79 -1.0997 -0.9999 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D21 compound treatment 166764.0 -285000.0 -1.69 170443.0 -310000.0 -1.77 -2.4464 -0.9998 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D22 compound treatment 92521.0 -359000.0 -2.14 60049.0 -421000.0 -2.39 -3.2027 -0.9984 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D23 compound treatment 384471.0 -66900.0 -0.4 493150.0 12200.0 0.07 -0.2326 -0.5751 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 D24 compound treatment 219776.0 -232000.0 -1.38 170787.0 -310000.0 -1.76 -2.2219 -0.9926 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E01 mock treatment 480761.0 29400.0 0.17 515652.0 34700.0 0.2 0.2631 0.9981 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E02 mock treatment 533897.0 82500.0 0.49 449815.0 -31100.0 -0.18 0.222 0.4255 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E03 compound treatment 100059.0 -351000.0 -2.09 103201.0 -378000.0 -2.15 -2.9975 -0.9999 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E04 compound treatment 426771.0 -24600.0 -0.15 396326.0 -84600.0 -0.48 -0.4439 -0.8825 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E05 compound treatment 48771.0 -403000.0 -2.4 71821.0 -409000.0 -2.33 -3.3395 -0.9999 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E06 compound treatment 168902.0 -283000.0 -1.68 174254.0 -307000.0 -1.74 -2.4221 -0.9998 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E07 compound treatment 285593.0 -166000.0 -0.99 475797.0 -5130.0 -0.03 -0.7184 -0.7277 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E08 compound treatment 518348.0 66900.0 0.4 444501.0 -36400.0 -0.21 0.1352 0.3011 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E09 mock treatment 349183.0 -102000.0 -0.61 498410.0 17500.0 0.1 -0.3599 -0.5838 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E10 mock treatment 391926.0 -59500.0 -0.35 445135.0 -35800.0 -0.2 -0.3943 -0.9655 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E11 compound treatment 264037.0 -187000.0 -1.12 251560.0 -229000.0 -1.3 -1.7108 -0.997 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E12 compound treatment 48384.0 -403000.0 -2.4 62691.0 -418000.0 -2.38 -3.3778 -1.0 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E13 compound treatment 410748.0 -40700.0 -0.24 469411.0 -11500.0 -0.07 -0.2174 -0.8673 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E14 compound treatment 65681.0 -386000.0 -2.3 81391.0 -400000.0 -2.27 -3.2299 -1.0 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E15 compound treatment 237476.0 -214000.0 -1.27 431182.0 -49700.0 -0.28 -1.1003 -0.8436 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E16 compound treatment 63948.0 -387000.0 -2.31 57294.0 -424000.0 -2.41 -3.3341 -0.9998 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E17 mock treatment 163938.0 -287000.0 -1.71 472566.0 -8360.0 -0.05 -1.2434 -0.7265 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E18 mock treatment 543826.0 92400.0 0.55 508130.0 27200.0 0.15 0.4983 0.8721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E19 compound treatment 336922.0 -114000.0 -0.68 296887.0 -184000.0 -1.05 -1.2219 -0.9784 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E20 compound treatment 44530.0 -407000.0 -2.42 86511.0 -394000.0 -2.24 -3.2983 -0.9993 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E21 compound treatment 318560.0 -133000.0 -0.79 370185.0 -111000.0 -0.63 -1.0044 -0.9936 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E22 compound treatment 96148.0 -355000.0 -2.11 106925.0 -374000.0 -2.13 -2.999 -1.0 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E23 compound treatment 342390.0 -109000.0 -0.65 524229.0 43300.0 0.25 -0.2847 -0.4102 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 E24 compound treatment 54384.0 -397000.0 -2.36 52408.0 -429000.0 -2.44 -3.3939 -0.9999 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F01 mock treatment 533334.0 81900.0 0.49 521661.0 40700.0 0.23 0.5085 0.9421 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F02 mock treatment 436218.0 -15200.0 -0.09 545494.0 64600.0 0.37 0.1957 0.5175 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F03 compound treatment 170180.0 -281000.0 -1.67 280339.0 -201000.0 -1.14 -1.9901 -0.9825 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F04 compound treatment 411204.0 -40200.0 -0.24 447074.0 -33900.0 -0.19 -0.3053 -0.9942 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F05 compound treatment 439919.0 -11500.0 -0.07 414670.0 -66300.0 -0.38 -0.3148 -0.822 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F06 compound treatment 183576.0 -268000.0 -1.59 170192.0 -311000.0 -1.77 -2.3766 -0.9987 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F07 compound treatment 173353.0 -278000.0 -1.65 181867.0 -299000.0 -1.7 -2.3727 -0.9999 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F08 compound treatment 252238.0 -199000.0 -1.19 393879.0 -87100.0 -0.5 -1.1882 -0.925 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F09 mock treatment 332248.0 -119000.0 -0.71 515799.0 34900.0 0.2 -0.3613 -0.4906 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F10 mock treatment 395275.0 -56100.0 -0.33 421264.0 -59700.0 -0.34 -0.4762 -1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F11 compound treatment 189416.0 -262000.0 -1.56 229123.0 -252000.0 -1.43 -2.1151 -0.9991 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F12 compound treatment 40743.0 -411000.0 -2.44 58581.0 -422000.0 -2.4 -3.4265 -1.0 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F13 compound treatment 166137.0 -285000.0 -1.7 274207.0 -207000.0 -1.18 -2.0318 -0.9839 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F14 compound treatment 476222.0 24800.0 0.15 341669.0 -139000.0 -0.79 -0.4556 -0.5655 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F15 compound treatment 160181.0 -291000.0 -1.73 331981.0 -149000.0 -0.85 -1.8245 -0.9458 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F16 compound treatment 300250.0 -151000.0 -0.9 460083.0 -20800.0 -0.12 -0.72 -0.7934 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F17 mock treatment 296798.0 -155000.0 -0.92 453176.0 -27800.0 -0.16 -0.7623 -0.8165 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F18 mock treatment 175092.0 -276000.0 -1.64 471825.0 -9100.0 -0.05 -1.1994 -0.729 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F19 compound treatment 256547.0 -195000.0 -1.16 277562.0 -203000.0 -1.16 -1.6378 -1.0 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F20 compound treatment 439225.0 -12200.0 -0.07 466585.0 -14300.0 -0.08 -0.109 -0.9983 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F21 compound treatment 268779.0 -183000.0 -1.09 353990.0 -127000.0 -0.72 -1.279 -0.9802 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F22 compound treatment 195097.0 -256000.0 -1.53 469772.0 -11200.0 -0.06 -1.1235 -0.7359 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F23 compound treatment 51042.0 -400000.0 -2.38 51970.0 -429000.0 -2.44 -3.4098 -0.9999 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 F24 compound treatment 98350.0 -353000.0 -2.1 175449.0 -305000.0 -1.74 -2.7142 -0.9955 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G01 compound treatment 464869.0 13500.0 0.08 400399.0 -80500.0 -0.46 -0.2672 -0.5747 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G02 compound treatment 316958.0 -134000.0 -0.8 322838.0 -158000.0 -0.9 -1.2015 -0.9983 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G03 mock treatment 425507.0 -25900.0 -0.15 437789.0 -43100.0 -0.25 -0.2825 -0.9749 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G04 mock treatment 429694.0 -21700.0 -0.13 456687.0 -24200.0 -0.14 -0.1889 -0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G05 compound treatment 412261.0 -39100.0 -0.23 464386.0 -16500.0 -0.09 -0.2313 -0.9204 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G06 compound treatment 438186.0 -13200.0 -0.08 436109.0 -44800.0 -0.25 -0.2359 -0.8842 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G07 compound treatment 62978.0 -388000.0 -2.31 70292.0 -411000.0 -2.34 -3.2859 -1.0 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G08 compound treatment 229360.0 -222000.0 -1.32 469974.0 -11000.0 -0.06 -0.9785 -0.7396 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G09 compound treatment 255772.0 -196000.0 -1.16 274483.0 -206000.0 -1.17 -1.6535 -1.0 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G10 compound treatment 341645.0 -110000.0 -0.65 355530.0 -125000.0 -0.71 -0.9662 -0.999 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G11 compound treatment 308704.0 -143000.0 -0.85 368279.0 -113000.0 -0.64 -1.0535 -0.9903 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G12 compound treatment 73524.0 -378000.0 -2.25 221444.0 -259000.0 -1.48 -2.6337 -0.9791 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G13 compound treatment 425711.0 -25700.0 -0.15 564044.0 83100.0 0.47 0.2261 0.4551 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G14 compound treatment 243024.0 -208000.0 -1.24 312244.0 -169000.0 -0.96 -1.5553 -0.9919 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G15 compound treatment 358388.0 -93000.0 -0.55 267154.0 -214000.0 -1.22 -1.2511 -0.9366 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G16 compound treatment 469219.0 17800.0 0.11 408660.0 -72300.0 -0.41 -0.2157 -0.5081 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G17 compound treatment 427854.0 -23600.0 -0.14 481149.0 219.0 0.0 -0.0982 -0.7008 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G18 compound treatment 329689.0 -122000.0 -0.72 434518.0 -46400.0 -0.26 -0.6989 -0.9064 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G19 mock treatment 535139.0 83700.0 0.5 520757.0 39800.0 0.23 0.5125 0.9363 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G20 mock treatment 241496.0 -210000.0 -1.25 389157.0 -91800.0 -0.52 -1.2524 -0.925 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G21 compound treatment 505682.0 54300.0 0.32 457058.0 -23900.0 -0.14 0.1324 0.3779 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G22 compound treatment 433179.0 -18200.0 -0.11 436908.0 -44000.0 -0.25 -0.2537 -0.93 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G23 compound treatment 116589.0 -335000.0 -1.99 214393.0 -267000.0 -1.52 -2.4808 -0.9909 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 G24 compound treatment 57365.0 -394000.0 -2.35 182520.0 -298000.0 -1.7 -2.8582 -0.9874 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H01 compound treatment 515749.0 64300.0 0.38 537071.0 56100.0 0.32 0.4965 0.9959 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H02 compound treatment 246689.0 -205000.0 -1.22 217133.0 -264000.0 -1.5 -1.9223 -0.9947 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H03 mock treatment 484967.0 33600.0 0.2 446278.0 -34700.0 -0.2 0.0019 0.0067 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H04 mock treatment 471170.0 19800.0 0.12 272081.0 -209000.0 -1.19 -0.7567 -0.634 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H05 compound treatment 242328.0 -209000.0 -1.24 299110.0 -182000.0 -1.03 -1.611 -0.9958 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H06 compound treatment 530847.0 79400.0 0.47 399158.0 -81800.0 -0.47 0.0055 0.0083 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H07 compound treatment 493305.0 41900.0 0.25 384586.0 -96300.0 -0.55 -0.2111 -0.3507 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H08 compound treatment 114939.0 -336000.0 -2.0 103743.0 -377000.0 -2.14 -2.9327 -0.9994 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H09 compound treatment 62303.0 -389000.0 -2.32 61727.0 -419000.0 -2.38 -3.3231 -0.9999 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H10 compound treatment 317020.0 -134000.0 -0.8 250132.0 -231000.0 -1.31 -1.4936 -0.9718 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H11 compound treatment 75772.0 -376000.0 -2.24 74847.0 -406000.0 -2.31 -3.2137 -0.9999 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H12 compound treatment 308117.0 -143000.0 -0.85 361898.0 -119000.0 -0.68 -1.0817 -0.9935 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H13 compound treatment 286655.0 -165000.0 -0.98 307516.0 -173000.0 -0.99 -1.3907 -1.0 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H14 compound treatment 296147.0 -155000.0 -0.92 243550.0 -237000.0 -1.35 -1.6079 -0.9829 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H15 compound treatment 246932.0 -204000.0 -1.22 464831.0 -16100.0 -0.09 -0.9252 -0.7582 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H16 compound treatment 386859.0 -64600.0 -0.38 478912.0 -2020.0 -0.01 -0.2798 -0.7279 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H17 compound treatment 220277.0 -231000.0 -1.38 487986.0 7060.0 0.04 -0.9443 -0.6862 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H18 compound treatment 220284.0 -231000.0 -1.38 415173.0 -65800.0 -0.37 -1.2371 -0.8678 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H19 mock treatment 453205.0 1790.0 0.01 426630.0 -54300.0 -0.31 -0.2108 -0.6822 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H20 mock treatment 499278.0 47900.0 0.28 546030.0 65100.0 0.37 0.4632 0.9916 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H21 compound treatment 456029.0 4620.0 0.03 434691.0 -46200.0 -0.26 -0.1665 -0.6298 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H22 compound treatment 358001.0 -93400.0 -0.56 518232.0 37300.0 0.21 -0.2431 -0.4086 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H23 compound treatment 508305.0 56900.0 0.34 559425.0 78500.0 0.45 0.5551 0.9907 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 H24 compound treatment 222467.0 -229000.0 -1.36 333426.0 -148000.0 -0.84 -1.5566 -0.9728 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I01 compound treatment 480638.0 29200.0 0.17 438227.0 -42700.0 -0.24 -0.0487 -0.1631 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I02 compound treatment 469988.0 18600.0 0.11 440732.0 -40200.0 -0.23 -0.0835 -0.3287 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I03 compound treatment 348995.0 -102000.0 -0.61 448526.0 -32400.0 -0.18 -0.5613 -0.8815 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I04 compound treatment 466688.0 15300.0 0.09 470528.0 -10400.0 -0.06 0.0225 0.2071 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I05 mock treatment 458316.0 6910.0 0.04 481870.0 940.0 0.01 0.0328 0.7924 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I06 mock treatment 445784.0 -5630.0 -0.03 436642.0 -44300.0 -0.25 -0.2018 -0.7941 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I07 compound treatment 213966.0 -237000.0 -1.41 167826.0 -313000.0 -1.78 -2.2583 -0.9934 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I08 compound treatment 350529.0 -101000.0 -0.6 374402.0 -107000.0 -0.61 -0.8529 -1.0 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I09 compound treatment 363888.0 -87500.0 -0.52 244468.0 -236000.0 -1.34 -1.3192 -0.9148 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I10 compound treatment 66605.0 -385000.0 -2.29 61657.0 -419000.0 -2.38 -3.3053 -0.9998 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I11 compound treatment 498435.0 47000.0 0.28 488100.0 7170.0 0.04 0.2267 0.8017 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I12 compound treatment 68092.0 -383000.0 -2.28 65247.0 -416000.0 -2.36 -3.2846 -0.9998 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I13 compound treatment 467144.0 15700.0 0.09 363707.0 -117000.0 -0.67 -0.4052 -0.6019 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I14 compound treatment 447519.0 -3890.0 -0.02 427954.0 -53000.0 -0.3 -0.2294 -0.7592 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I15 compound treatment 262618.0 -189000.0 -1.12 386921.0 -94000.0 -0.53 -1.1725 -0.9423 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I16 compound treatment 245835.0 -206000.0 -1.22 201044.0 -280000.0 -1.59 -1.9906 -0.9916 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I17 compound treatment 379469.0 -71900.0 -0.43 393818.0 -87100.0 -0.5 -0.653 -0.9974 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I18 compound treatment 503085.0 51700.0 0.31 555920.0 75000.0 0.43 0.519 0.9871 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I19 compound treatment 395402.0 -56000.0 -0.33 167987.0 -313000.0 -1.78 -1.4941 -0.8252 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I20 compound treatment 517392.0 66000.0 0.39 308012.0 -173000.0 -0.98 -0.4177 -0.3944 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I21 mock treatment 500470.0 49100.0 0.29 287185.0 -194000.0 -1.1 -0.5726 -0.5024 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I22 mock treatment 420215.0 -31200.0 -0.19 434083.0 -46800.0 -0.27 -0.3197 -0.9844 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I23 compound treatment 410159.0 -41300.0 -0.25 492827.0 11900.0 0.07 -0.1258 -0.4938 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 I24 compound treatment 149166.0 -302000.0 -1.8 144165.0 -337000.0 -1.92 -2.6261 -0.9995 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J01 compound treatment 493042.0 41600.0 0.25 548839.0 67900.0 0.39 0.4483 0.977 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J02 compound treatment 275991.0 -175000.0 -1.04 374886.0 -106000.0 -0.6 -1.1646 -0.966 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J03 compound treatment 450085.0 -1330.0 -0.01 483728.0 2800.0 0.02 0.0057 0.3196 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J04 compound treatment 498679.0 47300.0 0.28 326597.0 -154000.0 -0.88 -0.4217 -0.4575 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J05 mock treatment 316746.0 -135000.0 -0.8 417933.0 -63000.0 -0.36 -0.82 -0.9341 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J06 mock treatment 422404.0 -29000.0 -0.17 454292.0 -26600.0 -0.15 -0.2292 -0.9979 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J07 compound treatment 252366.0 -199000.0 -1.18 403356.0 -77600.0 -0.44 -1.1496 -0.9094 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J08 compound treatment 159248.0 -292000.0 -1.74 249854.0 -231000.0 -1.31 -2.1587 -0.9905 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J09 compound treatment 168625.0 -283000.0 -1.68 148211.0 -333000.0 -1.89 -2.5279 -0.9983 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J10 compound treatment 457171.0 5760.0 0.03 412364.0 -68600.0 -0.39 -0.2515 -0.6425 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J11 compound treatment 384486.0 -66900.0 -0.4 445027.0 -35900.0 -0.2 -0.426 -0.9518 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J12 compound treatment 112817.0 -339000.0 -2.02 92610.0 -388000.0 -2.21 -2.9864 -0.999 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J13 compound treatment 230141.0 -221000.0 -1.32 165963.0 -315000.0 -1.79 -2.1977 -0.9886 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J14 compound treatment 187953.0 -263000.0 -1.57 370402.0 -111000.0 -0.63 -1.5532 -0.9194 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J15 compound treatment 61040.0 -390000.0 -2.32 60527.0 -420000.0 -2.39 -3.3333 -0.9999 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J16 compound treatment 64121.0 -387000.0 -2.3 49043.0 -432000.0 -2.46 -3.3665 -0.9995 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J17 compound treatment 47456.0 -404000.0 -2.4 60320.0 -421000.0 -2.39 -3.3913 -1.0 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J18 compound treatment 450473.0 -937.0 -0.01 427414.0 -53500.0 -0.3 -0.2191 -0.7199 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J19 compound treatment 445355.0 -6060.0 -0.04 129837.0 -351000.0 -2.0 -1.4373 -0.7198 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J20 compound treatment 355572.0 -95800.0 -0.57 319861.0 -161000.0 -0.92 -1.051 -0.974 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J21 mock treatment 515711.0 64300.0 0.38 467641.0 -13300.0 -0.08 0.2172 0.5567 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J22 mock treatment 478336.0 26900.0 0.16 462193.0 -18700.0 -0.11 0.038 0.1973 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J23 compound treatment 276874.0 -175000.0 -1.04 248962.0 -232000.0 -1.32 -1.6673 -0.993 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 J24 compound treatment 107416.0 -344000.0 -2.05 635744.0 155000.0 0.88 -0.8251 -0.3702 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K01 compound treatment 496191.0 44800.0 0.27 534662.0 53700.0 0.31 0.4045 0.9977 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K02 compound treatment 521474.0 70100.0 0.42 517255.0 36300.0 0.21 0.4409 0.9475 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K03 compound treatment 396475.0 -54900.0 -0.33 514128.0 33200.0 0.19 -0.0977 -0.2587 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K04 compound treatment 482984.0 31600.0 0.19 487730.0 6800.0 0.04 0.1602 0.8351 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K05 compound treatment 472819.0 21400.0 0.13 571510.0 90600.0 0.52 0.4543 0.8562 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K06 compound treatment 474649.0 23200.0 0.14 575395.0 94500.0 0.54 0.4777 0.8611 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K07 mock treatment 301056.0 -150000.0 -0.89 190092.0 -291000.0 -1.65 -1.8022 -0.9584 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K08 mock treatment 495094.0 43700.0 0.26 554562.0 73600.0 0.42 0.4799 0.9737 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K09 compound treatment 382299.0 -69100.0 -0.41 135266.0 -346000.0 -1.97 -1.6808 -0.8369 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K10 compound treatment 58329.0 -393000.0 -2.34 28019.0 -453000.0 -2.58 -3.4754 -0.9988 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K11 compound treatment 434943.0 -16500.0 -0.1 533521.0 52600.0 0.3 0.1422 0.4518 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K12 compound treatment 348473.0 -103000.0 -0.61 551161.0 70200.0 0.4 -0.1508 -0.2062 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K13 compound treatment 223464.0 -228000.0 -1.36 302638.0 -178000.0 -1.01 -1.6762 -0.9897 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K14 compound treatment 302521.0 -149000.0 -0.89 216841.0 -264000.0 -1.5 -1.6885 -0.9683 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K15 mock treatment 481613.0 30200.0 0.18 151439.0 -329000.0 -1.87 -1.1978 -0.6364 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K16 mock treatment 483688.0 32300.0 0.19 516818.0 35900.0 0.2 0.2801 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K17 compound treatment 403813.0 -47600.0 -0.28 491879.0 10900.0 0.06 -0.1563 -0.5388 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K18 compound treatment 270578.0 -181000.0 -1.08 530129.0 49200.0 0.28 -0.5632 -0.5064 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K19 compound treatment 370563.0 -80800.0 -0.48 454714.0 -26200.0 -0.15 -0.4456 -0.8847 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K20 compound treatment 412577.0 -38800.0 -0.23 487195.0 6270.0 0.04 -0.1382 -0.5911 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K21 compound treatment 258818.0 -193000.0 -1.15 349140.0 -132000.0 -0.75 -1.3404 -0.9788 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K22 compound treatment 369849.0 -81600.0 -0.49 500575.0 19600.0 0.11 -0.2642 -0.5305 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K23 mock treatment 354057.0 -97400.0 -0.58 537212.0 56300.0 0.32 -0.1834 -0.277 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 K24 mock treatment 503207.0 51800.0 0.31 294835.0 -186000.0 -1.06 -0.5303 -0.4811 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L01 compound treatment 400816.0 -50600.0 -0.3 357752.0 -123000.0 -0.7 -0.7082 -0.9289 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L02 compound treatment 272850.0 -179000.0 -1.06 430784.0 -50100.0 -0.29 -0.9531 -0.8662 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L03 compound treatment 58361.0 -393000.0 -2.34 50995.0 -430000.0 -2.44 -3.3829 -0.9998 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L04 compound treatment 433213.0 -18200.0 -0.11 429405.0 -51500.0 -0.29 -0.2838 -0.9084 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L05 compound treatment 387227.0 -64200.0 -0.38 450756.0 -30200.0 -0.17 -0.3914 -0.9348 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L06 compound treatment 488564.0 37200.0 0.22 535021.0 54100.0 0.31 0.3739 0.9869 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L07 mock treatment 513942.0 62500.0 0.37 513091.0 32200.0 0.18 0.3925 0.9465 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L08 mock treatment 554818.0 103000.0 0.62 508690.0 27800.0 0.16 0.5468 0.8606 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L09 compound treatment 491109.0 39700.0 0.24 586102.0 105000.0 0.6 0.59 0.9174 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L10 compound treatment 584326.0 133000.0 0.79 498983.0 18100.0 0.1 0.6319 0.7922 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L11 compound treatment 545993.0 94600.0 0.56 504036.0 23100.0 0.13 0.4909 0.8493 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L12 compound treatment 509159.0 57700.0 0.34 511834.0 30900.0 0.18 0.3673 0.9515 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L13 compound treatment 57676.0 -394000.0 -2.34 55989.0 -425000.0 -2.42 -3.3657 -0.9999 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L14 compound treatment 287501.0 -164000.0 -0.98 196190.0 -285000.0 -1.62 -1.8348 -0.9706 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L15 mock treatment 512342.0 60900.0 0.36 535390.0 54500.0 0.31 0.4754 0.9969 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L16 mock treatment 320603.0 -131000.0 -0.78 514912.0 34000.0 0.19 -0.4138 -0.5159 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L17 compound treatment 458290.0 6880.0 0.04 522188.0 41300.0 0.23 0.1949 0.8181 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L18 compound treatment 205497.0 -246000.0 -1.46 496871.0 15900.0 0.09 -0.9708 -0.662 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L19 compound treatment 283402.0 -168000.0 -1.0 463566.0 -17400.0 -0.1 -0.7768 -0.7732 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L20 compound treatment 361169.0 -90200.0 -0.54 474968.0 -5960.0 -0.03 -0.4037 -0.7502 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L21 compound treatment 461965.0 10600.0 0.06 521119.0 40200.0 0.23 0.206 0.8692 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L22 compound treatment 430253.0 -21200.0 -0.13 488419.0 7490.0 0.04 -0.0589 -0.4433 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L23 mock treatment 298025.0 -153000.0 -0.91 550101.0 69200.0 0.39 -0.3673 -0.3696 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 L24 mock treatment 484060.0 32600.0 0.19 521975.0 41000.0 0.23 0.3024 0.9958 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M01 compound treatment 319789.0 -132000.0 -0.78 367708.0 -113000.0 -0.64 -1.0092 -0.9953 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M02 compound treatment 105114.0 -346000.0 -2.06 205564.0 -275000.0 -1.57 -2.5646 -0.9908 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M03 compound treatment 461417.0 10000.0 0.06 459594.0 -21300.0 -0.12 -0.0437 -0.3232 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M04 compound treatment 454949.0 3540.0 0.02 570060.0 89100.0 0.51 0.3733 0.7359 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M05 compound treatment 568765.0 117000.0 0.7 605218.0 124000.0 0.71 0.9936 1.0 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M06 compound treatment 69371.0 -382000.0 -2.27 67551.0 -413000.0 -2.35 -3.27 -0.9999 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M07 compound treatment 68947.0 -382000.0 -2.28 62275.0 -419000.0 -2.38 -3.293 -0.9997 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M08 compound treatment 65670.0 -386000.0 -2.3 63088.0 -418000.0 -2.38 -3.3035 -0.9999 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M09 mock treatment 230518.0 -221000.0 -1.31 623277.0 142000.0 0.81 -0.3572 -0.2314 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M10 mock treatment 532207.0 80800.0 0.48 613050.0 132000.0 0.75 0.8713 0.9767 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M11 compound treatment 256642.0 -195000.0 -1.16 375576.0 -105000.0 -0.6 -1.2433 -0.9528 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M12 compound treatment 59455.0 -392000.0 -2.33 66137.0 -415000.0 -2.36 -3.3174 -1.0 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M13 mock treatment 570333.0 119000.0 0.71 615303.0 134000.0 0.76 1.0408 0.9993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M14 mock treatment 376051.0 -75400.0 -0.45 574660.0 93700.0 0.53 0.0598 0.0858 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M15 compound treatment 59678.0 -392000.0 -2.33 58238.0 -423000.0 -2.4 -3.3482 -0.9999 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M16 compound treatment 571317.0 120000.0 0.71 506330.0 25400.0 0.14 0.6067 0.8333 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M17 compound treatment 142615.0 -309000.0 -1.84 149158.0 -332000.0 -1.89 -2.6336 -0.9999 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M18 compound treatment 546587.0 95200.0 0.57 548152.0 67200.0 0.38 0.6708 0.9817 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M19 compound treatment 51837.0 -400000.0 -2.38 54428.0 -427000.0 -2.43 -3.3965 -1.0 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M20 compound treatment 460138.0 8730.0 0.05 525680.0 44800.0 0.25 0.2167 0.8342 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M21 compound treatment 134537.0 -317000.0 -1.89 222503.0 -258000.0 -1.47 -2.3727 -0.9924 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M22 compound treatment 396644.0 -54800.0 -0.33 465602.0 -15300.0 -0.09 -0.2921 -0.8658 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M23 compound treatment 469602.0 18200.0 0.11 514755.0 33800.0 0.19 0.2126 0.963 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 M24 compound treatment 307505.0 -144000.0 -0.86 343659.0 -137000.0 -0.78 -1.1576 -0.9989 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N01 compound treatment 523074.0 71700.0 0.43 528500.0 47600.0 0.27 0.4929 0.9759 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N02 compound treatment 396584.0 -54800.0 -0.33 409563.0 -71400.0 -0.41 -0.5177 -0.9941 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N03 compound treatment 295935.0 -155000.0 -0.93 462193.0 -18700.0 -0.11 -0.7296 -0.7834 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N04 compound treatment 192735.0 -259000.0 -1.54 295818.0 -185000.0 -1.05 -1.8329 -0.9828 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N05 compound treatment 410974.0 -40400.0 -0.24 433685.0 -47200.0 -0.27 -0.3601 -0.9985 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N06 compound treatment 523035.0 71600.0 0.43 540423.0 59500.0 0.34 0.5406 0.9934 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N07 compound treatment 443274.0 -8140.0 -0.05 447554.0 -33400.0 -0.19 -0.1684 -0.86 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N08 compound treatment 420743.0 -30700.0 -0.18 456600.0 -24300.0 -0.14 -0.2269 -0.9907 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N09 mock treatment 557686.0 106000.0 0.63 544003.0 63100.0 0.36 0.7009 0.9639 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N10 mock treatment 682912.0 232000.0 1.38 553371.0 72400.0 0.41 1.2655 0.88 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N11 compound treatment 383807.0 -67600.0 -0.4 512927.0 32000.0 0.18 -0.1558 -0.3529 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N12 compound treatment 513096.0 61700.0 0.37 381930.0 -99000.0 -0.56 -0.1385 -0.2061 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N13 mock treatment 572874.0 121000.0 0.72 516074.0 35100.0 0.2 0.6525 0.87 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N14 mock treatment 607760.0 156000.0 0.93 512362.0 31400.0 0.18 0.7844 0.8278 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N15 compound treatment 536087.0 84700.0 0.5 511588.0 30700.0 0.17 0.4796 0.8994 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N16 compound treatment 307713.0 -144000.0 -0.86 308512.0 -172000.0 -0.98 -1.298 -0.9977 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N17 compound treatment 566943.0 116000.0 0.69 554750.0 73800.0 0.42 0.783 0.972 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N18 compound treatment 590008.0 139000.0 0.82 481781.0 851.0 0.0 0.5867 0.7112 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N19 compound treatment 58038.0 -393000.0 -2.34 63563.0 -417000.0 -2.37 -3.3337 -1.0 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N20 compound treatment 549288.0 97900.0 0.58 504186.0 23300.0 0.13 0.5054 0.8461 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N21 compound treatment 342423.0 -109000.0 -0.65 591303.0 110000.0 0.63 -0.0148 -0.0164 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N22 compound treatment 302518.0 -149000.0 -0.89 337462.0 -143000.0 -0.82 -1.2035 -0.9991 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N23 compound treatment 446902.0 -4510.0 -0.03 506207.0 25300.0 0.14 0.0827 0.5654 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 N24 compound treatment 516374.0 65000.0 0.39 565445.0 84500.0 0.48 0.6132 0.9942 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O01 compound treatment 603813.0 152000.0 0.91 574562.0 93600.0 0.53 1.0179 0.9678 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O02 compound treatment 400011.0 -51400.0 -0.31 448600.0 -32300.0 -0.18 -0.3463 -0.9703 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O03 compound treatment 449734.0 -1680.0 -0.01 445507.0 -35400.0 -0.2 -0.1495 -0.7412 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O04 compound treatment 79080.0 -372000.0 -2.22 146093.0 -335000.0 -1.9 -2.9133 -0.9971 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O05 compound treatment 548934.0 97500.0 0.58 518421.0 37500.0 0.21 0.5612 0.9076 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O06 compound treatment 590239.0 139000.0 0.83 569893.0 89000.0 0.51 0.942 0.9723 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O07 compound treatment 240128.0 -211000.0 -1.26 491906.0 11000.0 0.06 -0.845 -0.6712 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O08 compound treatment 527375.0 76000.0 0.45 567849.0 86900.0 0.49 0.6692 0.999 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O09 compound treatment 86170.0 -365000.0 -2.17 259603.0 -221000.0 -1.26 -2.427 -0.9663 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O10 compound treatment 170798.0 -281000.0 -1.67 543556.0 62600.0 0.36 -0.9291 -0.5441 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O11 mock treatment 663553.0 212000.0 1.26 524321.0 43400.0 0.25 1.0672 0.8296 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O12 mock treatment 300908.0 -151000.0 -0.9 526746.0 45800.0 0.26 -0.4491 -0.4815 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O13 compound treatment 624162.0 173000.0 1.03 513263.0 32300.0 0.18 0.857 0.8205 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O14 compound treatment 46932.0 -404000.0 -2.41 62720.0 -418000.0 -2.38 -3.3838 -1.0 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O15 compound treatment 522101.0 70700.0 0.42 430309.0 -50600.0 -0.29 0.0939 0.1843 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O16 compound treatment 363562.0 -87800.0 -0.52 366669.0 -114000.0 -0.65 -0.8291 -0.9942 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O17 compound treatment 408868.0 -42500.0 -0.25 450598.0 -30300.0 -0.17 -0.301 -0.9825 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O18 compound treatment 384154.0 -67300.0 -0.4 408408.0 -72500.0 -0.41 -0.5747 -0.9999 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O19 compound treatment 171367.0 -280000.0 -1.67 352506.0 -128000.0 -0.73 -1.6949 -0.9315 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O20 compound treatment 489018.0 37600.0 0.22 455441.0 -25500.0 -0.14 0.0558 0.2092 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O21 compound treatment 546190.0 94800.0 0.56 498747.0 17800.0 0.1 0.4705 0.821 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O22 compound treatment 341202.0 -110000.0 -0.66 350534.0 -130000.0 -0.74 -0.9881 -0.9981 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O23 compound treatment 50714.0 -401000.0 -2.38 53727.0 -427000.0 -2.43 -3.4041 -1.0 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 O24 compound treatment 149146.0 -302000.0 -1.8 175105.0 -306000.0 -1.74 -2.5018 -0.9999 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P01 compound treatment 516918.0 65500.0 0.39 534409.0 53500.0 0.3 0.4907 0.9925 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P02 compound treatment 521270.0 69900.0 0.42 528402.0 47500.0 0.27 0.4849 0.9781 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P03 compound treatment 333664.0 -118000.0 -0.7 584562.0 104000.0 0.59 -0.0788 -0.086 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P04 compound treatment 516391.0 65000.0 0.39 481416.0 486.0 0.0 0.2754 0.7121 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P05 compound treatment 48933.0 -402000.0 -2.4 61482.0 -419000.0 -2.39 -3.3804 -1.0 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P06 compound treatment 317351.0 -134000.0 -0.8 465912.0 -15000.0 -0.09 -0.6245 -0.7783 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P07 compound treatment 563431.0 112000.0 0.67 416426.0 -64500.0 -0.37 0.212 0.2787 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P08 compound treatment 510929.0 59500.0 0.35 474068.0 -6860.0 -0.04 0.2229 0.6254 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P09 compound treatment 640925.0 190000.0 1.13 411861.0 -69100.0 -0.39 0.5198 0.4352 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P10 compound treatment 599953.0 149000.0 0.88 459965.0 -21000.0 -0.12 0.5408 0.6063 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P11 mock treatment 427644.0 -23800.0 -0.14 524618.0 43700.0 0.25 0.0757 0.2647 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P12 mock treatment 625223.0 174000.0 1.03 473649.0 -7280.0 -0.04 0.7022 0.6783 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P13 compound treatment 555573.0 104000.0 0.62 462030.0 -18900.0 -0.11 0.3623 0.5759 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P14 compound treatment 601078.0 150000.0 0.89 533061.0 52100.0 0.3 0.8395 0.8942 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P15 compound treatment 640804.0 189000.0 1.13 273169.0 -208000.0 -1.18 -0.0384 -0.0235 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P16 compound treatment 85301.0 -366000.0 -2.18 100141.0 -381000.0 -2.17 -3.0719 -1.0 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P17 compound treatment 498523.0 47100.0 0.28 493035.0 12100.0 0.07 0.2469 0.8553 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P18 compound treatment 85479.0 -366000.0 -2.18 80669.0 -400000.0 -2.28 -3.1494 -0.9998 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P19 compound treatment 368102.0 -83300.0 -0.5 364107.0 -117000.0 -0.66 -0.8203 -0.9896 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P20 compound treatment 567907.0 116000.0 0.69 403133.0 -77800.0 -0.44 0.1774 0.2157 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P21 compound treatment 634398.0 183000.0 1.09 620608.0 140000.0 0.79 1.3317 0.988 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P22 compound treatment 420262.0 -31100.0 -0.19 372125.0 -109000.0 -0.62 -0.5686 -0.8803 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P23 compound treatment 385342.0 -66100.0 -0.39 476842.0 -4090.0 -0.02 -0.2945 -0.7476 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2097 P24 compound treatment 505423.0 54000.0 0.32 562381.0 81500.0 0.46 0.5548 0.9841 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A01 compound treatment 467004.0 -10000.0 -0.06 453747.0 12200.0 0.07 0.0071 0.0774 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A02 compound treatment 264233.0 -213000.0 -1.27 355752.0 -85800.0 -0.49 -1.2403 -0.914 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A03 compound treatment 233141.0 -244000.0 -1.45 312269.0 -129000.0 -0.74 -1.546 -0.9503 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A04 compound treatment 493455.0 16400.0 0.1 409765.0 -31800.0 -0.18 -0.0585 -0.2846 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A05 compound treatment 83535.0 -393000.0 -2.34 84260.0 -357000.0 -2.03 -3.0924 -0.9975 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A06 compound treatment 348394.0 -129000.0 -0.77 348446.0 -93100.0 -0.53 -0.9155 -0.9838 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A07 compound treatment 504115.0 27100.0 0.16 431568.0 -9950.0 -0.06 0.0741 0.4333 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A08 compound treatment 186624.0 -290000.0 -1.73 349239.0 -92300.0 -0.52 -1.5931 -0.8821 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A09 compound treatment 493470.0 16500.0 0.1 485343.0 43800.0 0.25 0.2455 0.9168 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A10 compound treatment 437807.0 -39200.0 -0.23 417792.0 -23700.0 -0.13 -0.2604 -0.9661 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A11 compound treatment 54103.0 -423000.0 -2.52 57631.0 -384000.0 -2.18 -3.3234 -0.9975 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A12 compound treatment 401536.0 -75500.0 -0.45 449797.0 8280.0 0.05 -0.2843 -0.6295 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A13 mock treatment 504948.0 27900.0 0.17 488679.0 47200.0 0.27 0.3072 0.9736 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A14 mock treatment 564617.0 87600.0 0.52 560067.0 119000.0 0.67 0.8454 0.9919 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A15 compound treatment 429957.0 -47000.0 -0.28 363090.0 -78400.0 -0.45 -0.5134 -0.9748 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A16 compound treatment 348478.0 -129000.0 -0.76 439524.0 -1990.0 -0.01 -0.5489 -0.7175 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A17 compound treatment 490008.0 13000.0 0.08 118034.0 -323000.0 -1.84 -1.2461 -0.6768 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A18 compound treatment 427609.0 -49400.0 -0.29 182853.0 -259000.0 -1.47 -1.248 -0.832 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A19 compound treatment 73575.0 -403000.0 -2.4 74040.0 -367000.0 -2.09 -3.1754 -0.9976 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A20 compound treatment 433407.0 -43600.0 -0.26 525032.0 83500.0 0.47 0.1523 0.2815 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A21 compound treatment 57842.0 -419000.0 -2.49 67645.0 -374000.0 -2.13 -3.2674 -0.9968 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A22 compound treatment 385223.0 -91800.0 -0.55 462275.0 20800.0 0.12 -0.3028 -0.5418 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A23 compound treatment 51619.0 -425000.0 -2.53 52028.0 -389000.0 -2.21 -3.3563 -0.9978 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 A24 compound treatment 325207.0 -152000.0 -0.9 335209.0 -106000.0 -0.6 -1.0663 -0.9809 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B01 compound treatment 92075.0 -385000.0 -2.29 71476.0 -370000.0 -2.1 -3.1079 -0.9991 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B02 compound treatment 412537.0 -64500.0 -0.38 449366.0 7850.0 0.04 -0.2397 -0.6207 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B03 compound treatment 444962.0 -32000.0 -0.19 180952.0 -261000.0 -1.48 -1.1826 -0.7916 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B04 compound treatment 482191.0 5190.0 0.03 437747.0 -3770.0 -0.02 0.0067 0.1773 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B05 compound treatment 466062.0 -10900.0 -0.07 309882.0 -132000.0 -0.75 -0.5754 -0.7657 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B06 compound treatment 331088.0 -146000.0 -0.87 148581.0 -293000.0 -1.67 -1.792 -0.9539 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B07 compound treatment 421053.0 -56000.0 -0.33 221177.0 -220000.0 -1.25 -1.1215 -0.865 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B08 compound treatment 298346.0 -179000.0 -1.06 173032.0 -268000.0 -1.53 -1.8315 -0.9844 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B09 compound treatment 335984.0 -141000.0 -0.84 123804.0 -318000.0 -1.81 -1.871 -0.9392 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B10 compound treatment 472219.0 -4790.0 -0.03 476707.0 35200.0 0.2 0.1214 0.6004 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B11 compound treatment 485266.0 8260.0 0.05 429331.0 -12200.0 -0.07 -0.0142 -0.1676 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B12 compound treatment 383994.0 -93000.0 -0.55 317360.0 -124000.0 -0.71 -0.8907 -0.9928 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B13 mock treatment 457259.0 -19700.0 -0.12 422115.0 -19400.0 -0.11 -0.1611 -0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B14 mock treatment 466662.0 -10300.0 -0.06 436535.0 -4980.0 -0.03 -0.0636 -0.938 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B15 compound treatment 394590.0 -82400.0 -0.49 320479.0 -121000.0 -0.69 -0.8335 -0.9862 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B16 compound treatment 445890.0 -31100.0 -0.19 387714.0 -53800.0 -0.31 -0.3473 -0.9711 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B17 compound treatment 404723.0 -72300.0 -0.43 353630.0 -87900.0 -0.5 -0.6576 -0.9972 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B18 compound treatment 313569.0 -163000.0 -0.97 283043.0 -158000.0 -0.9 -1.325 -0.9993 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B19 compound treatment 104731.0 -372000.0 -2.22 133157.0 -308000.0 -1.75 -2.8066 -0.9933 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B20 compound treatment 102185.0 -375000.0 -2.23 93951.0 -348000.0 -1.98 -2.975 -0.9982 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B21 compound treatment 355415.0 -122000.0 -0.72 587648.0 146000.0 0.83 0.0759 0.0689 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B22 compound treatment 466014.0 -11000.0 -0.07 389260.0 -52300.0 -0.3 -0.2564 -0.8426 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B23 compound treatment 478449.0 1440.0 0.01 405361.0 -36200.0 -0.21 -0.1393 -0.677 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 B24 compound treatment 577000.0 100000.0 0.6 511793.0 70300.0 0.4 0.7034 0.9812 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C01 compound treatment 398094.0 -78900.0 -0.47 470098.0 28600.0 0.16 -0.2172 -0.437 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C02 compound treatment 487204.0 10200.0 0.06 322617.0 -119000.0 -0.68 -0.4352 -0.6411 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C03 compound treatment 430037.0 -47000.0 -0.28 445660.0 4140.0 0.02 -0.181 -0.6452 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C04 compound treatment 169111.0 -308000.0 -1.83 159176.0 -282000.0 -1.61 -2.431 -0.9978 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C05 compound treatment 82914.0 -394000.0 -2.35 156992.0 -285000.0 -1.62 -2.8026 -0.9836 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C06 compound treatment 447912.0 -29100.0 -0.17 450781.0 9260.0 0.05 -0.0852 -0.4707 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C07 compound treatment 493285.0 16300.0 0.1 475552.0 34000.0 0.19 0.2054 0.9488 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C08 compound treatment 430289.0 -46700.0 -0.28 419177.0 -22300.0 -0.13 -0.2864 -0.937 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C09 compound treatment 37279.0 -440000.0 -2.62 67580.0 -374000.0 -2.13 -3.3542 -0.9947 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C10 compound treatment 60884.0 -416000.0 -2.48 58849.0 -383000.0 -2.18 -3.2899 -0.9979 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C11 mock treatment 378235.0 -98800.0 -0.59 413403.0 -28100.0 -0.16 -0.5287 -0.8679 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C12 mock treatment 442175.0 -34800.0 -0.21 414730.0 -26800.0 -0.15 -0.2543 -0.9885 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C13 compound treatment 68241.0 -409000.0 -2.43 68303.0 -373000.0 -2.12 -3.2209 -0.9977 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C14 compound treatment 431646.0 -45400.0 -0.27 465441.0 23900.0 0.14 -0.0947 -0.3132 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C15 mock treatment 451287.0 -25700.0 -0.15 245685.0 -196000.0 -1.11 -0.8957 -0.7968 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C16 mock treatment 463293.0 -13700.0 -0.08 425346.0 -16200.0 -0.09 -0.1227 -0.9982 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C17 compound treatment 215232.0 -262000.0 -1.56 182873.0 -259000.0 -1.47 -2.1417 -0.9996 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C18 compound treatment 220921.0 -256000.0 -1.52 81098.0 -360000.0 -2.05 -2.527 -0.9894 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C19 compound treatment 90906.0 -386000.0 -2.3 120187.0 -321000.0 -1.83 -2.9169 -0.9936 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C20 compound treatment 358032.0 -119000.0 -0.71 216060.0 -225000.0 -1.28 -1.4073 -0.9608 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C21 compound treatment 36454.0 -441000.0 -2.62 45452.0 -396000.0 -2.25 -3.4466 -0.9971 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C22 compound treatment 165237.0 -312000.0 -1.86 280372.0 -161000.0 -0.92 -1.96 -0.9471 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C23 compound treatment 245576.0 -231000.0 -1.38 490148.0 48600.0 0.28 -0.7784 -0.5541 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 C24 compound treatment 252307.0 -225000.0 -1.34 490899.0 49400.0 0.28 -0.747 -0.5467 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D01 compound treatment 326116.0 -151000.0 -0.9 358189.0 -83300.0 -0.47 -0.9701 -0.9554 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D02 compound treatment 441797.0 -35200.0 -0.21 420404.0 -21100.0 -0.12 -0.2331 -0.9651 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D03 compound treatment 434000.0 -43000.0 -0.26 470716.0 29200.0 0.17 -0.0636 -0.2084 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D04 compound treatment 430291.0 -46700.0 -0.28 442352.0 835.0 0.0 -0.1932 -0.6949 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D05 compound treatment 387514.0 -89500.0 -0.53 381043.0 -60500.0 -0.34 -0.6198 -0.9776 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D06 compound treatment 142266.0 -335000.0 -1.99 157777.0 -284000.0 -1.61 -2.5496 -0.9945 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D07 compound treatment 311103.0 -166000.0 -0.99 85450.0 -356000.0 -2.02 -2.13 -0.9455 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D08 compound treatment 238970.0 -238000.0 -1.42 172230.0 -269000.0 -1.53 -2.0846 -0.9992 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D09 compound treatment 419533.0 -57500.0 -0.34 383686.0 -57800.0 -0.33 -0.4744 -0.9998 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D10 compound treatment 97040.0 -380000.0 -2.26 83462.0 -358000.0 -2.04 -3.0388 -0.9986 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D11 mock treatment 409526.0 -67500.0 -0.4 441683.0 166.0 0.0 -0.2833 -0.7054 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D12 mock treatment 445987.0 -31000.0 -0.18 365232.0 -76300.0 -0.43 -0.4373 -0.9275 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D13 compound treatment 349033.0 -128000.0 -0.76 365390.0 -76100.0 -0.43 -0.8447 -0.9642 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D14 compound treatment 373266.0 -104000.0 -0.62 354355.0 -87200.0 -0.5 -0.7871 -0.9941 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D15 mock treatment 433236.0 -43800.0 -0.26 417788.0 -23700.0 -0.13 -0.2796 -0.9531 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D16 mock treatment 359558.0 -117000.0 -0.7 433354.0 -8160.0 -0.05 -0.5271 -0.7524 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D17 compound treatment 106023.0 -371000.0 -2.21 110537.0 -331000.0 -1.88 -2.8921 -0.9968 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D18 compound treatment 411763.0 -65200.0 -0.39 456182.0 14700.0 0.08 -0.2156 -0.5429 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D19 compound treatment 348426.0 -129000.0 -0.77 387379.0 -54100.0 -0.31 -0.7588 -0.9199 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D20 compound treatment 76386.0 -401000.0 -2.38 127063.0 -314000.0 -1.79 -2.9504 -0.99 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D21 compound treatment 350630.0 -126000.0 -0.75 170772.0 -271000.0 -1.54 -1.6205 -0.9457 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D22 compound treatment 224315.0 -253000.0 -1.5 466560.0 25000.0 0.14 -0.9627 -0.6373 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D23 compound treatment 113030.0 -364000.0 -2.17 428807.0 -12700.0 -0.07 -1.5828 -0.7303 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 D24 compound treatment 201446.0 -276000.0 -1.64 484356.0 42800.0 0.24 -0.9874 -0.5955 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E01 mock treatment 540301.0 63300.0 0.38 523603.0 82100.0 0.47 0.5964 0.9943 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E02 mock treatment 459081.0 -17900.0 -0.11 421058.0 -20500.0 -0.12 -0.1577 -0.9991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E03 compound treatment 402660.0 -74300.0 -0.44 450801.0 9280.0 0.05 -0.2755 -0.6183 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E04 compound treatment 391544.0 -85500.0 -0.51 445342.0 3820.0 0.02 -0.3443 -0.6763 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E05 compound treatment 512990.0 36000.0 0.21 391194.0 -50300.0 -0.29 -0.0509 -0.1425 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E06 compound treatment 362112.0 -115000.0 -0.68 340741.0 -101000.0 -0.57 -0.8887 -0.9961 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E07 compound treatment 455939.0 -21100.0 -0.13 466973.0 25500.0 0.14 0.0137 0.0716 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E08 compound treatment 343173.0 -134000.0 -0.8 362710.0 -78800.0 -0.45 -0.8801 -0.963 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E09 mock treatment 476709.0 -297.0 0.0 427322.0 -14200.0 -0.08 -0.0583 -0.7224 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E10 mock treatment 444345.0 -32700.0 -0.19 415665.0 -25900.0 -0.15 -0.2414 -0.9905 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E11 compound treatment 378983.0 -98000.0 -0.58 341528.0 -100000.0 -0.57 -0.8146 -0.9999 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E12 compound treatment 70567.0 -406000.0 -2.42 69373.0 -372000.0 -2.12 -3.2069 -0.9978 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E13 compound treatment 212636.0 -264000.0 -1.57 313007.0 -129000.0 -0.73 -1.6293 -0.9392 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E14 compound treatment 395081.0 -81900.0 -0.49 434445.0 -7070.0 -0.04 -0.3732 -0.7628 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E15 compound treatment 59531.0 -417000.0 -2.48 65504.0 -376000.0 -2.14 -3.2689 -0.9972 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E16 compound treatment 387657.0 -89300.0 -0.53 268537.0 -173000.0 -0.98 -1.0716 -0.9583 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E17 mock treatment 490303.0 13300.0 0.08 450776.0 9260.0 0.05 0.0932 0.9804 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E18 mock treatment 465539.0 -11500.0 -0.07 444786.0 3270.0 0.02 -0.0351 -0.4964 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E19 compound treatment 57070.0 -420000.0 -2.5 48204.0 -393000.0 -2.24 -3.3488 -0.9985 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E20 compound treatment 482323.0 5320.0 0.03 146698.0 -295000.0 -1.68 -1.1631 -0.6936 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E21 compound treatment 341005.0 -136000.0 -0.81 431170.0 -10300.0 -0.06 -0.6139 -0.7565 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E22 compound treatment 508235.0 31200.0 0.19 366701.0 -74800.0 -0.43 -0.1694 -0.3649 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E23 compound treatment 344427.0 -133000.0 -0.79 332069.0 -109000.0 -0.62 -0.998 -0.9931 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 E24 compound treatment 480043.0 3040.0 0.02 409706.0 -31800.0 -0.18 -0.1151 -0.6333 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F01 mock treatment 473626.0 -3380.0 -0.02 563024.0 122000.0 0.69 0.4744 0.6862 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F02 mock treatment 395351.0 -81700.0 -0.49 450210.0 8690.0 0.05 -0.3087 -0.6319 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F03 compound treatment 395561.0 -81400.0 -0.48 276949.0 -165000.0 -0.94 -1.0045 -0.9531 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F04 compound treatment 473443.0 -3560.0 -0.02 335566.0 -106000.0 -0.6 -0.441 -0.7315 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F05 compound treatment 338966.0 -138000.0 -0.82 343584.0 -97900.0 -0.56 -0.9747 -0.9821 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F06 compound treatment 463314.0 -13700.0 -0.08 466341.0 24800.0 0.14 0.0422 0.2589 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F07 compound treatment 174833.0 -302000.0 -1.8 132944.0 -309000.0 -1.75 -2.5124 -0.9999 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F08 compound treatment 382024.0 -95000.0 -0.57 301036.0 -140000.0 -0.8 -0.9646 -0.9857 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F09 mock treatment 407171.0 -69800.0 -0.42 164410.0 -277000.0 -1.58 -1.4082 -0.8641 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F10 mock treatment 379876.0 -97100.0 -0.58 556542.0 115000.0 0.65 0.0538 0.0616 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F11 compound treatment 387065.0 -89900.0 -0.54 380460.0 -61100.0 -0.35 -0.624 -0.978 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F12 compound treatment 375722.0 -101000.0 -0.6 377802.0 -63700.0 -0.36 -0.6824 -0.9703 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F13 compound treatment 406102.0 -70900.0 -0.42 395546.0 -46000.0 -0.26 -0.4832 -0.9735 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F14 compound treatment 254229.0 -223000.0 -1.33 279576.0 -162000.0 -0.92 -1.5887 -0.9841 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F15 compound treatment 178740.0 -298000.0 -1.78 196924.0 -245000.0 -1.39 -2.2387 -0.9927 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F16 compound treatment 82581.0 -394000.0 -2.35 96172.0 -345000.0 -1.96 -3.0485 -0.9961 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F17 mock treatment 430279.0 -46700.0 -0.28 454430.0 12900.0 0.07 -0.1447 -0.5031 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F18 mock treatment 398565.0 -78400.0 -0.47 446092.0 4570.0 0.03 -0.3117 -0.6667 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F19 compound treatment 53566.0 -423000.0 -2.52 50832.0 -391000.0 -2.22 -3.353 -0.998 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F20 compound treatment 497791.0 20800.0 0.12 463395.0 21900.0 0.12 0.1754 1.0 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F21 compound treatment 396588.0 -80400.0 -0.48 426014.0 -15500.0 -0.09 -0.4008 -0.8235 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F22 compound treatment 434003.0 -43000.0 -0.26 389073.0 -52400.0 -0.3 -0.3919 -0.9971 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F23 compound treatment 69658.0 -407000.0 -2.42 58097.0 -383000.0 -2.18 -3.256 -0.9986 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 F24 compound treatment 276245.0 -201000.0 -1.19 266751.0 -175000.0 -0.99 -1.5476 -0.9958 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G01 compound treatment 35304.0 -442000.0 -2.63 86991.0 -355000.0 -2.02 -3.2844 -0.9914 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G02 compound treatment 381094.0 -95900.0 -0.57 295679.0 -146000.0 -0.83 -0.9901 -0.9834 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G03 mock treatment 477464.0 458.0 0.0 537707.0 96200.0 0.55 0.3887 0.7106 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G04 mock treatment 107092.0 -370000.0 -2.2 487243.0 45700.0 0.26 -1.3728 -0.6193 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G05 compound treatment 228494.0 -249000.0 -1.48 442212.0 695.0 0.0 -1.043 -0.7052 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G06 compound treatment 401209.0 -75800.0 -0.45 323417.0 -118000.0 -0.67 -0.7939 -0.9813 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G07 compound treatment 138732.0 -338000.0 -2.01 117936.0 -324000.0 -1.84 -2.7247 -0.999 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G08 compound treatment 117530.0 -359000.0 -2.14 60370.0 -381000.0 -2.17 -3.0454 -1.0 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G09 compound treatment 407213.0 -69800.0 -0.42 390464.0 -51100.0 -0.29 -0.499 -0.9847 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G10 compound treatment 159343.0 -318000.0 -1.89 470564.0 29000.0 0.17 -1.22 -0.6429 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G11 compound treatment 58216.0 -419000.0 -2.49 64287.0 -377000.0 -2.15 -3.2793 -0.9972 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G12 compound treatment 338971.0 -138000.0 -0.82 309299.0 -132000.0 -0.75 -1.1126 -0.999 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G13 compound treatment 255639.0 -221000.0 -1.32 309327.0 -132000.0 -0.75 -1.4631 -0.9646 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G14 compound treatment 286917.0 -190000.0 -1.13 328324.0 -113000.0 -0.64 -1.2551 -0.9643 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G15 compound treatment 277962.0 -199000.0 -1.18 412971.0 -28500.0 -0.16 -0.9524 -0.7966 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G16 compound treatment 180494.0 -297000.0 -1.76 231700.0 -210000.0 -1.19 -2.0915 -0.9818 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G17 compound treatment 63609.0 -413000.0 -2.46 17674.0 -424000.0 -2.41 -3.444 -0.9999 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G18 compound treatment 78384.0 -399000.0 -2.37 176366.0 -265000.0 -1.51 -2.7437 -0.9761 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G19 mock treatment 511492.0 34500.0 0.21 243363.0 -198000.0 -1.13 -0.6517 -0.569 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G20 mock treatment 447053.0 -30000.0 -0.18 430261.0 -11300.0 -0.06 -0.1713 -0.9045 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G21 compound treatment 267667.0 -209000.0 -1.25 266575.0 -175000.0 -0.99 -1.5844 -0.9938 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G22 compound treatment 265788.0 -211000.0 -1.26 226116.0 -215000.0 -1.22 -1.755 -0.9999 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G23 compound treatment 515648.0 38600.0 0.23 544899.0 103000.0 0.59 0.5783 0.9161 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 G24 compound treatment 360358.0 -117000.0 -0.69 283090.0 -158000.0 -0.9 -1.1279 -0.9917 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H01 compound treatment 435071.0 -41900.0 -0.25 260121.0 -181000.0 -1.03 -0.9059 -0.8536 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H02 compound treatment 179091.0 -298000.0 -1.77 200262.0 -241000.0 -1.37 -2.2238 -0.992 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H03 mock treatment 445482.0 -31500.0 -0.19 464829.0 23300.0 0.13 -0.0389 -0.1694 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H04 mock treatment 423107.0 -53900.0 -0.32 192993.0 -249000.0 -1.41 -1.2262 -0.8461 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H05 compound treatment 448425.0 -28600.0 -0.17 211479.0 -230000.0 -1.31 -1.0453 -0.7924 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H06 compound treatment 412001.0 -65000.0 -0.39 415076.0 -26400.0 -0.15 -0.3799 -0.9152 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H07 compound treatment 269081.0 -208000.0 -1.24 200391.0 -241000.0 -1.37 -1.8446 -0.9987 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H08 compound treatment 346033.0 -131000.0 -0.78 214680.0 -227000.0 -1.29 -1.4633 -0.9709 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H09 compound treatment 177413.0 -300000.0 -1.78 114006.0 -328000.0 -1.86 -2.5777 -0.9998 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H10 compound treatment 318481.0 -159000.0 -0.94 360441.0 -81100.0 -0.46 -0.9931 -0.9458 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H11 compound treatment 193565.0 -283000.0 -1.69 278213.0 -163000.0 -0.93 -1.8495 -0.9605 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H12 compound treatment 327782.0 -149000.0 -0.89 314371.0 -127000.0 -0.72 -1.1392 -0.9948 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H13 compound treatment 386104.0 -90900.0 -0.54 209429.0 -232000.0 -1.32 -1.3158 -0.9225 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H14 compound treatment 350205.0 -127000.0 -0.75 349116.0 -92400.0 -0.53 -0.9052 -0.9843 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H15 compound treatment 207689.0 -269000.0 -1.6 195772.0 -246000.0 -1.4 -2.1215 -0.9977 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H16 compound treatment 188965.0 -288000.0 -1.71 160462.0 -281000.0 -1.6 -2.3423 -0.9994 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H17 compound treatment 303933.0 -173000.0 -1.03 238595.0 -203000.0 -1.15 -1.5443 -0.9984 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H18 compound treatment 314768.0 -162000.0 -0.97 147472.0 -294000.0 -1.67 -1.8651 -0.9659 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H19 mock treatment 189959.0 -287000.0 -1.71 241036.0 -200000.0 -1.14 -2.0141 -0.9807 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H20 mock treatment 418243.0 -58800.0 -0.35 394252.0 -47300.0 -0.27 -0.4373 -0.9915 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H21 compound treatment 461347.0 -15700.0 -0.09 234389.0 -207000.0 -1.18 -0.8988 -0.7607 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H22 compound treatment 295645.0 -181000.0 -1.08 65752.0 -376000.0 -2.14 -2.2742 -0.95 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H23 compound treatment 346073.0 -131000.0 -0.78 70569.0 -371000.0 -2.11 -2.0426 -0.9083 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 H24 compound treatment 394393.0 -82600.0 -0.49 327966.0 -114000.0 -0.65 -0.8043 -0.9909 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I01 compound treatment 61560.0 -415000.0 -2.47 68015.0 -374000.0 -2.12 -3.2502 -0.9971 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I02 compound treatment 359555.0 -117000.0 -0.7 515143.0 73600.0 0.42 -0.1982 -0.2433 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I03 compound treatment 55274.0 -422000.0 -2.51 57854.0 -384000.0 -2.18 -3.3175 -0.9976 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I04 compound treatment 357883.0 -119000.0 -0.71 345154.0 -96400.0 -0.55 -0.8888 -0.9919 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I05 mock treatment 460478.0 -16500.0 -0.1 448763.0 7250.0 0.04 -0.0404 -0.379 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I06 mock treatment 468125.0 -8880.0 -0.05 421216.0 -20300.0 -0.12 -0.119 -0.9373 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I07 compound treatment 470747.0 -6260.0 -0.04 430055.0 -11500.0 -0.07 -0.0724 -0.9648 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I08 compound treatment 436320.0 -40700.0 -0.24 372746.0 -68800.0 -0.39 -0.4478 -0.9734 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I09 compound treatment 386270.0 -90700.0 -0.54 356764.0 -84800.0 -0.48 -0.7226 -0.9984 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I10 compound treatment 482368.0 5360.0 0.03 363402.0 -78100.0 -0.44 -0.2915 -0.6546 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I11 compound treatment 68664.0 -408000.0 -2.43 100856.0 -341000.0 -1.94 -3.0883 -0.9937 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I12 compound treatment 385779.0 -91200.0 -0.54 293059.0 -148000.0 -0.84 -0.9809 -0.9772 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I13 compound treatment 407458.0 -69500.0 -0.41 421390.0 -20100.0 -0.11 -0.3736 -0.87 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I14 compound treatment 241327.0 -236000.0 -1.4 218706.0 -223000.0 -1.27 -1.8878 -0.9987 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I15 compound treatment 57808.0 -419000.0 -2.49 55924.0 -386000.0 -2.19 -3.3146 -0.9979 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I16 compound treatment 311806.0 -165000.0 -0.98 368042.0 -73500.0 -0.42 -0.9907 -0.9273 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I17 compound treatment 520089.0 43100.0 0.26 481769.0 40300.0 0.23 0.3432 0.9984 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I18 compound treatment 416719.0 -60300.0 -0.36 246103.0 -195000.0 -1.11 -1.0395 -0.8902 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I19 compound treatment 91812.0 -385000.0 -2.29 181937.0 -260000.0 -1.48 -2.6648 -0.9773 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I20 compound treatment 427758.0 -49200.0 -0.29 184514.0 -257000.0 -1.46 -1.2407 -0.8323 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I21 mock treatment 506933.0 29900.0 0.18 234192.0 -207000.0 -1.18 -0.7077 -0.5936 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I22 mock treatment 507224.0 30200.0 0.18 280575.0 -161000.0 -0.92 -0.52 -0.5575 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I23 compound treatment 51578.0 -425000.0 -2.53 46173.0 -395000.0 -2.25 -3.3801 -0.9982 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 I24 compound treatment 479551.0 2550.0 0.02 140403.0 -301000.0 -1.71 -1.2001 -0.7008 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J01 compound treatment 427446.0 -49600.0 -0.29 463911.0 22400.0 0.13 -0.1185 -0.3689 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J02 compound treatment 465903.0 -11100.0 -0.07 627862.0 186000.0 1.06 0.7026 0.6617 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J03 compound treatment 224779.0 -252000.0 -1.5 187538.0 -254000.0 -1.44 -2.0827 -0.9998 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J04 compound treatment 327606.0 -149000.0 -0.89 182714.0 -259000.0 -1.47 -1.6694 -0.9709 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J05 mock treatment 442340.0 -34700.0 -0.21 241721.0 -200000.0 -1.14 -0.9493 -0.8221 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J06 mock treatment 406968.0 -70000.0 -0.42 425084.0 -16400.0 -0.09 -0.3608 -0.8447 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J07 compound treatment 474521.0 -2480.0 -0.01 193328.0 -248000.0 -1.41 -1.0085 -0.7145 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J08 compound treatment 316694.0 -160000.0 -0.95 610685.0 169000.0 0.96 0.0056 0.0041 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J09 compound treatment 434298.0 -42700.0 -0.25 410746.0 -30800.0 -0.17 -0.3035 -0.9834 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J10 compound treatment 336382.0 -141000.0 -0.84 195221.0 -246000.0 -1.4 -1.5822 -0.9697 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J11 compound treatment 456573.0 -20400.0 -0.12 465852.0 24300.0 0.14 0.0119 0.0644 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J12 compound treatment 53857.0 -423000.0 -2.52 62795.0 -379000.0 -2.15 -3.3036 -0.997 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J13 compound treatment 367323.0 -110000.0 -0.65 363786.0 -77700.0 -0.44 -0.7741 -0.982 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J14 compound treatment 342767.0 -134000.0 -0.8 395880.0 -45600.0 -0.26 -0.7484 -0.891 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J15 compound treatment 99436.0 -378000.0 -2.25 70856.0 -371000.0 -2.11 -3.0794 -0.9995 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J16 compound treatment 412291.0 -64700.0 -0.39 266304.0 -175000.0 -1.0 -0.9769 -0.9145 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J17 compound treatment 202561.0 -274000.0 -1.63 199726.0 -242000.0 -1.38 -2.1272 -0.9963 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J18 compound treatment 162348.0 -315000.0 -1.87 167310.0 -274000.0 -1.56 -2.4268 -0.9959 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J19 compound treatment 261657.0 -215000.0 -1.28 179028.0 -262000.0 -1.49 -1.9618 -0.9971 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J20 compound treatment 237845.0 -239000.0 -1.42 242910.0 -199000.0 -1.13 -1.8051 -0.9934 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J21 mock treatment 235303.0 -242000.0 -1.44 499570.0 58100.0 0.33 -0.7837 -0.531 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J22 mock treatment 455005.0 -22000.0 -0.13 511985.0 70500.0 0.4 0.1908 0.4525 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J23 compound treatment 182003.0 -295000.0 -1.76 208623.0 -233000.0 -1.32 -2.178 -0.9903 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 J24 compound treatment 482750.0 5740.0 0.03 407850.0 -33700.0 -0.19 -0.1112 -0.5718 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K01 compound treatment 422474.0 -54500.0 -0.32 509008.0 67500.0 0.38 0.0419 0.0834 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K02 compound treatment 451370.0 -25600.0 -0.15 497586.0 56100.0 0.32 0.1176 0.3326 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K03 compound treatment 405829.0 -71200.0 -0.42 485831.0 44300.0 0.25 -0.1213 -0.2462 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K04 compound treatment 418542.0 -58500.0 -0.35 424338.0 -17200.0 -0.1 -0.3151 -0.8719 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K05 compound treatment 40436.0 -437000.0 -2.6 70425.0 -371000.0 -2.11 -3.3294 -0.9947 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K06 compound treatment 479714.0 2710.0 0.02 428833.0 -12700.0 -0.07 -0.0396 -0.5359 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K07 mock treatment 462575.0 -14400.0 -0.09 424238.0 -17300.0 -0.1 -0.1302 -0.9977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K08 mock treatment 528559.0 51600.0 0.31 463360.0 21800.0 0.12 0.3048 0.9208 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K09 compound treatment 62957.0 -414000.0 -2.46 64353.0 -377000.0 -2.14 -3.2591 -0.9976 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K10 compound treatment 450110.0 -26900.0 -0.16 516658.0 75100.0 0.43 0.189 0.4141 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K11 compound treatment 60576.0 -416000.0 -2.48 60343.0 -381000.0 -2.17 -3.2852 -0.9978 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K12 compound treatment 287683.0 -189000.0 -1.13 217556.0 -224000.0 -1.27 -1.6973 -0.9981 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K13 compound treatment 86966.0 -390000.0 -2.32 69357.0 -372000.0 -2.12 -3.1379 -0.9989 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K14 compound treatment 273480.0 -204000.0 -1.21 293182.0 -148000.0 -0.84 -1.453 -0.9844 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K15 mock treatment 231526.0 -245000.0 -1.46 489223.0 47700.0 0.27 -0.8412 -0.5661 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K16 mock treatment 451411.0 -25600.0 -0.15 504537.0 63000.0 0.36 0.1457 0.3742 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K17 compound treatment 429287.0 -47700.0 -0.28 425456.0 -16100.0 -0.09 -0.2654 -0.8896 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K18 compound treatment 318418.0 -159000.0 -0.94 355221.0 -86300.0 -0.49 -1.0144 -0.9536 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K19 compound treatment 434768.0 -42200.0 -0.25 375154.0 -66400.0 -0.38 -0.4446 -0.9805 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K20 compound treatment 427268.0 -49700.0 -0.3 340569.0 -101000.0 -0.57 -0.6152 -0.9525 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K21 compound treatment 494430.0 17400.0 0.1 396883.0 -44600.0 -0.25 -0.1062 -0.3872 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K22 compound treatment 58079.0 -419000.0 -2.49 35024.0 -406000.0 -2.31 -3.3975 -0.9993 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K23 mock treatment 542657.0 65700.0 0.39 450433.0 8920.0 0.05 0.3121 0.7922 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 K24 mock treatment 495425.0 18400.0 0.11 415581.0 -25900.0 -0.15 -0.0268 -0.1457 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L01 compound treatment 187242.0 -290000.0 -1.72 408158.0 -33400.0 -0.19 -1.3536 -0.7802 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L02 compound treatment 484796.0 7790.0 0.05 269149.0 -172000.0 -0.98 -0.6603 -0.6729 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L03 compound treatment 250568.0 -226000.0 -1.35 282631.0 -159000.0 -0.9 -1.5918 -0.9811 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L04 compound treatment 194761.0 -282000.0 -1.68 232473.0 -209000.0 -1.19 -2.0284 -0.9857 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L05 compound treatment 464663.0 -12300.0 -0.07 405461.0 -36100.0 -0.21 -0.1969 -0.9042 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L06 compound treatment 497355.0 20300.0 0.12 417284.0 -24200.0 -0.14 -0.0118 -0.0644 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L07 mock treatment 523143.0 46100.0 0.27 448892.0 7370.0 0.04 0.2238 0.8058 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L08 mock treatment 520147.0 43100.0 0.26 465944.0 24400.0 0.14 0.2798 0.9584 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L09 compound treatment 472384.0 -4620.0 -0.03 498195.0 56700.0 0.32 0.2085 0.6444 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L10 compound treatment 226605.0 -250000.0 -1.49 250927.0 -191000.0 -1.08 -1.8201 -0.9878 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L11 compound treatment 66412.0 -411000.0 -2.44 15595.0 -426000.0 -2.42 -3.4406 -1.0 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L12 compound treatment 130785.0 -346000.0 -2.06 156721.0 -285000.0 -1.62 -2.6022 -0.9929 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L13 compound treatment 524633.0 47600.0 0.28 429421.0 -12100.0 -0.07 0.1518 0.5204 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L14 compound treatment 263160.0 -214000.0 -1.27 339510.0 -102000.0 -0.58 -1.3101 -0.9367 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L15 mock treatment 495928.0 18900.0 0.11 523733.0 82200.0 0.47 0.4102 0.853 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L16 mock treatment 458095.0 -18900.0 -0.11 312772.0 -129000.0 -0.73 -0.5973 -0.8063 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L17 compound treatment 363646.0 -113000.0 -0.67 174607.0 -267000.0 -1.52 -1.5503 -0.9334 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L18 compound treatment 319877.0 -157000.0 -0.94 393739.0 -47800.0 -0.27 -0.8534 -0.8763 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L19 compound treatment 387293.0 -89700.0 -0.53 193829.0 -248000.0 -1.41 -1.3735 -0.9118 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L20 compound treatment 309152.0 -168000.0 -1.0 332987.0 -109000.0 -0.62 -1.1428 -0.9732 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L21 compound treatment 412282.0 -64700.0 -0.39 327057.0 -114000.0 -0.65 -0.7326 -0.9687 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L22 compound treatment 400359.0 -76600.0 -0.46 104060.0 -337000.0 -1.92 -1.6795 -0.8515 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L23 mock treatment 512665.0 35700.0 0.21 382312.0 -59200.0 -0.34 -0.088 -0.2211 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 L24 mock treatment 443120.0 -33900.0 -0.2 449615.0 8100.0 0.05 -0.11 -0.5319 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M01 compound treatment 488919.0 11900.0 0.07 535335.0 93800.0 0.53 0.4274 0.7941 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M02 compound treatment 566832.0 89800.0 0.53 525352.0 83800.0 0.48 0.7151 0.9984 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M03 compound treatment 411032.0 -66000.0 -0.39 416098.0 -25400.0 -0.14 -0.3799 -0.9079 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M04 compound treatment 204070.0 -273000.0 -1.62 367236.0 -74300.0 -0.42 -1.4473 -0.8623 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M05 compound treatment 241152.0 -236000.0 -1.4 465700.0 24200.0 0.14 -0.8953 -0.6348 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M06 compound treatment 555413.0 78400.0 0.47 440299.0 -1220.0 -0.01 0.3251 0.6965 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M07 compound treatment 584536.0 108000.0 0.64 439495.0 -2020.0 -0.01 0.4444 0.6943 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M08 compound treatment 669022.0 192000.0 1.14 583659.0 142000.0 0.81 1.3796 0.9856 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M09 mock treatment 581079.0 104000.0 0.62 553176.0 112000.0 0.63 0.887 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M10 mock treatment 644805.0 168000.0 1.0 526009.0 84500.0 0.48 1.0459 0.9438 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M11 compound treatment 266931.0 -210000.0 -1.25 195699.0 -246000.0 -1.4 -1.8725 -0.9984 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M12 compound treatment 516031.0 39000.0 0.23 467463.0 25900.0 0.15 0.2686 0.976 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M13 mock treatment 566657.0 89700.0 0.53 541564.0 100000.0 0.57 0.7796 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M14 mock treatment 588968.0 112000.0 0.67 529458.0 87900.0 0.5 0.8248 0.99 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M15 compound treatment 545388.0 68400.0 0.41 493013.0 51500.0 0.29 0.4948 0.987 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M16 compound treatment 562765.0 85800.0 0.51 508575.0 67100.0 0.38 0.6305 0.9897 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M17 compound treatment 438745.0 -38300.0 -0.23 540062.0 98500.0 0.56 0.2353 0.3889 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M18 compound treatment 526873.0 49900.0 0.3 226859.0 -215000.0 -1.22 -0.6533 -0.52 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M19 compound treatment 498927.0 21900.0 0.13 595815.0 154000.0 0.88 0.7127 0.8034 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M20 compound treatment 472436.0 -4570.0 -0.03 397046.0 -44500.0 -0.25 -0.1981 -0.7787 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M21 compound treatment 513385.0 36400.0 0.22 487335.0 45800.0 0.26 0.3373 0.9958 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M22 compound treatment 270552.0 -206000.0 -1.23 288264.0 -153000.0 -0.87 -1.4851 -0.9858 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M23 compound treatment 531708.0 54700.0 0.33 517595.0 76100.0 0.43 0.5361 0.9902 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 M24 compound treatment 100313.0 -377000.0 -2.24 24082.0 -417000.0 -2.37 -3.2638 -0.9996 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N01 compound treatment 458158.0 -18800.0 -0.11 463213.0 21700.0 0.12 0.0079 0.0475 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N02 compound treatment 303101.0 -174000.0 -1.03 283875.0 -158000.0 -0.9 -1.3657 -0.9974 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N03 compound treatment 508289.0 31300.0 0.19 440517.0 -1000.0 -0.01 0.1276 0.6852 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N04 compound treatment 240386.0 -237000.0 -1.41 263940.0 -178000.0 -1.01 -1.7098 -0.9867 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N05 compound treatment 510348.0 33300.0 0.2 518882.0 77400.0 0.44 0.4514 0.9353 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N06 compound treatment 491091.0 14100.0 0.08 493716.0 52200.0 0.3 0.2692 0.8727 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N07 compound treatment 553926.0 76900.0 0.46 526042.0 84500.0 0.48 0.6636 0.9997 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N08 compound treatment 87896.0 -389000.0 -2.32 73230.0 -368000.0 -2.09 -3.1184 -0.9987 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N09 mock treatment 588415.0 111000.0 0.66 507133.0 65600.0 0.37 0.7327 0.963 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N10 mock treatment 537969.0 61000.0 0.36 279264.0 -162000.0 -0.92 -0.3959 -0.3993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N11 compound treatment 472726.0 -4280.0 -0.03 241163.0 -200000.0 -1.14 -0.8237 -0.7227 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N12 compound treatment 54866.0 -422000.0 -2.51 61693.0 -380000.0 -2.16 -3.3038 -0.9972 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N13 mock treatment 526703.0 49700.0 0.3 589077.0 148000.0 0.84 0.8025 0.902 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N14 mock treatment 439471.0 -37500.0 -0.22 334732.0 -107000.0 -0.61 -0.5874 -0.9077 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N15 compound treatment 105007.0 -372000.0 -2.21 142642.0 -299000.0 -1.7 -2.7673 -0.9915 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N16 compound treatment 326359.0 -151000.0 -0.9 208240.0 -233000.0 -1.33 -1.572 -0.9818 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N17 compound treatment 134250.0 -343000.0 -2.04 84418.0 -357000.0 -2.03 -2.8784 -1.0 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N18 compound treatment 58264.0 -419000.0 -2.49 58424.0 -383000.0 -2.18 -3.3027 -0.9978 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N19 compound treatment 336055.0 -141000.0 -0.84 349469.0 -92000.0 -0.52 -0.9633 -0.9742 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N20 compound treatment 400579.0 -76400.0 -0.45 405935.0 -35600.0 -0.2 -0.4647 -0.9335 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N21 compound treatment 525417.0 48400.0 0.29 488735.0 47200.0 0.27 0.3936 0.9994 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N22 compound treatment 60581.0 -416000.0 -2.48 43064.0 -398000.0 -2.27 -3.3547 -0.999 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N23 compound treatment 447258.0 -29700.0 -0.18 403567.0 -38000.0 -0.22 -0.2778 -0.9952 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 N24 compound treatment 57772.0 -419000.0 -2.5 64139.0 -377000.0 -2.15 -3.2817 -0.9972 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O01 compound treatment 516421.0 39400.0 0.23 561861.0 120000.0 0.68 0.6498 0.8982 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O02 compound treatment 431825.0 -45200.0 -0.27 394153.0 -47400.0 -0.27 -0.3806 -1.0 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O03 compound treatment 537806.0 60800.0 0.36 467815.0 26300.0 0.15 0.3616 0.9236 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O04 compound treatment 523930.0 46900.0 0.28 421053.0 -20500.0 -0.12 0.1152 0.3807 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O05 compound treatment 606974.0 130000.0 0.77 579906.0 138000.0 0.79 1.1034 1.0 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O06 compound treatment 498723.0 21700.0 0.13 529671.0 88200.0 0.5 0.4459 0.8613 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O07 compound treatment 635354.0 158000.0 0.94 512639.0 71100.0 0.4 0.9524 0.9287 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O08 compound treatment 186139.0 -291000.0 -1.73 155766.0 -286000.0 -1.62 -2.3731 -0.9995 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O09 compound treatment 489286.0 12300.0 0.07 472151.0 30600.0 0.17 0.1749 0.9256 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O10 compound treatment 512694.0 35700.0 0.21 465398.0 23900.0 0.14 0.2462 0.9767 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O11 mock treatment 580777.0 104000.0 0.62 641156.0 200000.0 1.14 1.2395 0.959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O12 mock treatment 577081.0 100000.0 0.6 529278.0 87800.0 0.5 0.774 0.9961 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O13 compound treatment 602610.0 126000.0 0.75 542951.0 101000.0 0.58 0.9365 0.9918 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O14 compound treatment 485208.0 8200.0 0.05 427962.0 -13600.0 -0.08 -0.02 -0.2191 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O15 compound treatment 260452.0 -217000.0 -1.29 422076.0 -19400.0 -0.11 -0.9895 -0.765 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O16 compound treatment 598258.0 121000.0 0.72 504993.0 63500.0 0.36 0.7655 0.9487 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O17 compound treatment 581653.0 105000.0 0.62 540086.0 98600.0 0.56 0.8367 0.9986 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O18 compound treatment 507427.0 30400.0 0.18 520384.0 78900.0 0.45 0.4452 0.9204 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O19 compound treatment 180014.0 -297000.0 -1.77 135000.0 -307000.0 -1.74 -2.4824 -1.0 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O20 compound treatment 422038.0 -55000.0 -0.33 533867.0 92300.0 0.53 0.14 0.2263 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O21 compound treatment 427849.0 -49200.0 -0.29 493802.0 52300.0 0.3 0.0034 0.0081 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O22 compound treatment 292848.0 -184000.0 -1.1 287412.0 -154000.0 -0.88 -1.3947 -0.9939 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O23 compound treatment 490075.0 13100.0 0.08 488649.0 47100.0 0.27 0.2445 0.8762 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 O24 compound treatment 398212.0 -78800.0 -0.47 430218.0 -11300.0 -0.06 -0.377 -0.7966 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P01 compound treatment 86598.0 -390000.0 -2.32 110685.0 -331000.0 -1.88 -2.9733 -0.9945 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P02 compound treatment 74140.0 -403000.0 -2.4 79287.0 -362000.0 -2.06 -3.152 -0.9971 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P03 compound treatment 314199.0 -163000.0 -0.97 550259.0 109000.0 0.62 -0.2479 -0.2156 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P04 compound treatment 120155.0 -357000.0 -2.12 112485.0 -329000.0 -1.87 -2.8248 -0.998 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P05 compound treatment 447561.0 -29400.0 -0.18 414459.0 -27100.0 -0.15 -0.2327 -0.9979 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P06 compound treatment 62107.0 -415000.0 -2.47 71207.0 -370000.0 -2.11 -3.2351 -0.9969 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P07 compound treatment 554723.0 77700.0 0.46 503436.0 61900.0 0.35 0.576 0.9909 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P08 compound treatment 68876.0 -408000.0 -2.43 72112.0 -369000.0 -2.1 -3.203 -0.9974 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P09 compound treatment 490359.0 13400.0 0.08 538979.0 97500.0 0.55 0.4481 0.8003 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P10 compound treatment 417036.0 -60000.0 -0.36 431116.0 -10400.0 -0.06 -0.2942 -0.8132 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P11 mock treatment 626170.0 149000.0 0.89 619193.0 178000.0 1.01 1.3422 0.9979 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P12 mock treatment 707850.0 231000.0 1.37 561993.0 120000.0 0.69 1.4559 0.9483 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P13 compound treatment 517242.0 40200.0 0.24 641358.0 200000.0 1.14 0.9729 0.8377 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P14 compound treatment 413794.0 -63200.0 -0.38 511014.0 69500.0 0.4 0.0134 0.0246 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P15 compound treatment 542950.0 65900.0 0.39 563420.0 122000.0 0.69 0.7677 0.9637 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P16 compound treatment 350633.0 -126000.0 -0.75 399945.0 -41600.0 -0.24 -0.699 -0.8866 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P17 compound treatment 509913.0 32900.0 0.2 389863.0 -51700.0 -0.29 -0.0692 -0.1961 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P18 compound treatment 243244.0 -234000.0 -1.39 193867.0 -248000.0 -1.41 -1.9796 -1.0 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P19 compound treatment 443034.0 -34000.0 -0.2 530402.0 88900.0 0.51 0.2145 0.3939 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P20 compound treatment 57486.0 -420000.0 -2.5 76652.0 -365000.0 -2.07 -3.2326 -0.9958 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P21 compound treatment 412714.0 -64300.0 -0.38 171401.0 -270000.0 -1.54 -1.3567 -0.8571 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P22 compound treatment 169833.0 -307000.0 -1.83 196084.0 -245000.0 -1.4 -2.2796 -0.9911 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P23 compound treatment 479426.0 2420.0 0.01 576471.0 135000.0 0.77 0.5529 0.7203 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2098 P24 compound treatment 66958.0 -410000.0 -2.44 66774.0 -375000.0 -2.13 -3.2325 -0.9977 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A01 compound treatment 340428.0 -106000.0 -0.63 563469.0 45700.0 0.26 -0.2627 -0.3846 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A02 compound treatment 183715.0 -263000.0 -1.56 121705.0 -396000.0 -2.25 -2.6985 -0.9841 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A03 compound treatment 516445.0 69900.0 0.42 509274.0 -8480.0 -0.05 0.2601 0.621 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A04 compound treatment 511130.0 64600.0 0.38 545834.0 28100.0 0.16 0.3848 0.9243 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A05 compound treatment 485773.0 39200.0 0.23 372974.0 -145000.0 -0.82 -0.417 -0.4873 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A06 compound treatment 515686.0 69200.0 0.41 526752.0 9000.0 0.05 0.3272 0.789 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A07 compound treatment 151794.0 -295000.0 -1.75 515802.0 -1950.0 -0.01 -1.2482 -0.7116 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A08 compound treatment 343208.0 -103000.0 -0.61 476157.0 -41600.0 -0.24 -0.6021 -0.9138 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A09 compound treatment 456070.0 9540.0 0.06 327071.0 -191000.0 -1.08 -0.7266 -0.6692 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A10 compound treatment 482776.0 36200.0 0.22 405754.0 -112000.0 -0.64 -0.2978 -0.4429 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A11 compound treatment 122304.0 -324000.0 -1.93 420703.0 -97000.0 -0.55 -1.7547 -0.8743 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A12 compound treatment 348502.0 -98000.0 -0.58 469759.0 -48000.0 -0.27 -0.6055 -0.9401 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A13 mock treatment 435385.0 -11100.0 -0.07 522213.0 4460.0 0.03 -0.0289 -0.4077 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A14 mock treatment 106915.0 -340000.0 -2.02 460875.0 -56900.0 -0.32 -1.6579 -0.81 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A15 compound treatment 488971.0 42400.0 0.25 482032.0 -35700.0 -0.2 0.035 0.1079 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A16 compound treatment 372251.0 -74300.0 -0.44 465353.0 -52400.0 -0.3 -0.5233 -0.9816 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A17 compound treatment 354523.0 -92000.0 -0.55 493763.0 -24000.0 -0.14 -0.4836 -0.8571 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A18 compound treatment 374224.0 -72300.0 -0.43 484881.0 -32900.0 -0.19 -0.4364 -0.9303 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A19 compound treatment 433264.0 -13300.0 -0.08 222634.0 -295000.0 -1.68 -1.2425 -0.7395 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A20 compound treatment 416040.0 -30500.0 -0.18 269138.0 -249000.0 -1.41 -1.128 -0.7914 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A21 compound treatment 64176.0 -382000.0 -2.28 66598.0 -451000.0 -2.57 -3.4232 -0.9982 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A22 compound treatment 419460.0 -27100.0 -0.16 323231.0 -195000.0 -1.11 -0.8961 -0.8016 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A23 compound treatment 122405.0 -324000.0 -1.93 109590.0 -408000.0 -2.32 -3.0053 -0.9958 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 A24 compound treatment 420011.0 -26500.0 -0.16 379094.0 -139000.0 -0.79 -0.6691 -0.8321 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B01 compound treatment 526299.0 79800.0 0.47 573655.0 55900.0 0.32 0.5605 0.981 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B02 compound treatment 507373.0 60800.0 0.36 620673.0 103000.0 0.59 0.6699 0.9734 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B03 compound treatment 484014.0 37500.0 0.22 554992.0 37200.0 0.21 0.3075 0.9997 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B04 compound treatment 216347.0 -230000.0 -1.37 253070.0 -265000.0 -1.51 -2.033 -0.9989 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B05 compound treatment 484331.0 37800.0 0.22 529404.0 11700.0 0.07 0.2059 0.8781 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B06 compound treatment 458045.0 11500.0 0.07 500048.0 -17700.0 -0.1 -0.0227 -0.1865 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B07 compound treatment 533076.0 86500.0 0.52 471757.0 -46000.0 -0.26 0.1793 0.3103 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B08 compound treatment 464632.0 18100.0 0.11 449788.0 -68000.0 -0.39 -0.1971 -0.4912 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B09 compound treatment 401323.0 -45200.0 -0.27 459939.0 -57800.0 -0.33 -0.4227 -0.995 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B10 compound treatment 185353.0 -261000.0 -1.55 431592.0 -86200.0 -0.49 -1.4456 -0.887 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B11 compound treatment 439364.0 -7160.0 -0.04 506004.0 -11700.0 -0.07 -0.0774 -0.9765 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B12 compound treatment 455240.0 8710.0 0.05 427364.0 -90400.0 -0.51 -0.3268 -0.6326 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B13 mock treatment 432962.0 -13600.0 -0.08 548123.0 30400.0 0.17 0.065 0.3412 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B14 mock treatment 461091.0 14600.0 0.09 392449.0 -125000.0 -0.71 -0.4426 -0.6166 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B15 compound treatment 97531.0 -349000.0 -2.08 119052.0 -399000.0 -2.27 -3.0719 -0.999 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B16 compound treatment 397085.0 -49400.0 -0.29 171441.0 -346000.0 -1.97 -1.6006 -0.8038 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B17 compound treatment 441423.0 -5100.0 -0.03 142996.0 -375000.0 -2.13 -1.5284 -0.7171 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B18 compound treatment 417347.0 -29200.0 -0.17 289471.0 -228000.0 -1.3 -1.0407 -0.7946 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B19 compound treatment 396577.0 -50000.0 -0.3 458394.0 -59400.0 -0.34 -0.4489 -0.998 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B20 compound treatment 390818.0 -55700.0 -0.33 475915.0 -41800.0 -0.24 -0.4027 -0.9867 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B21 compound treatment 380422.0 -66100.0 -0.39 416323.0 -101000.0 -0.58 -0.686 -0.9826 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B22 compound treatment 390277.0 -56300.0 -0.33 435584.0 -82200.0 -0.47 -0.5671 -0.9866 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B23 compound treatment 455025.0 8500.0 0.05 401092.0 -117000.0 -0.66 -0.4333 -0.6513 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 B24 compound treatment 436382.0 -10100.0 -0.06 473167.0 -44600.0 -0.25 -0.222 -0.8517 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C01 compound treatment 478091.0 31600.0 0.19 554244.0 36500.0 0.21 0.2796 0.9988 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C02 compound treatment 522760.0 76200.0 0.45 643482.0 126000.0 0.72 0.8264 0.9759 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C03 compound treatment 475982.0 29500.0 0.18 551688.0 33900.0 0.19 0.2604 0.9988 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C04 compound treatment 473010.0 26500.0 0.16 483978.0 -33800.0 -0.19 -0.0244 -0.098 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C05 compound treatment 246857.0 -200000.0 -1.19 516575.0 -1180.0 -0.01 -0.845 -0.7111 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C06 compound treatment 187589.0 -259000.0 -1.54 497638.0 -20100.0 -0.11 -1.1706 -0.7575 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C07 compound treatment 449106.0 2580.0 0.02 500638.0 -17100.0 -0.1 -0.058 -0.5883 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C08 compound treatment 454532.0 8000.0 0.05 476733.0 -41000.0 -0.23 -0.1313 -0.5513 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C09 compound treatment 449228.0 2700.0 0.02 396254.0 -121000.0 -0.69 -0.4772 -0.6905 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C10 compound treatment 437347.0 -9180.0 -0.05 406647.0 -111000.0 -0.63 -0.4854 -0.7654 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C11 mock treatment 98099.0 -348000.0 -2.07 458290.0 -59500.0 -0.34 -1.7054 -0.8117 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C12 mock treatment 380963.0 -65600.0 -0.39 509247.0 -8500.0 -0.05 -0.3101 -0.7887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C13 compound treatment 463253.0 16700.0 0.1 466739.0 -51000.0 -0.29 -0.1347 -0.4393 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C14 compound treatment 165714.0 -281000.0 -1.67 397236.0 -121000.0 -0.69 -1.6664 -0.9225 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C15 mock treatment 223024.0 -224000.0 -1.33 452007.0 -65700.0 -0.37 -1.2049 -0.8721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C16 mock treatment 443975.0 -2550.0 -0.02 467395.0 -50400.0 -0.29 -0.2132 -0.7436 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C17 compound treatment 444169.0 -2360.0 -0.01 469780.0 -48000.0 -0.27 -0.2028 -0.7425 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C18 compound treatment 392183.0 -54300.0 -0.32 199240.0 -319000.0 -1.81 -1.5095 -0.8204 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C19 compound treatment 401689.0 -44800.0 -0.27 451310.0 -66400.0 -0.38 -0.4559 -0.9855 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C20 compound treatment 391551.0 -55000.0 -0.33 525782.0 8030.0 0.05 -0.1991 -0.6026 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C21 compound treatment 67619.0 -379000.0 -2.26 77814.0 -440000.0 -2.5 -3.3636 -0.9987 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C22 compound treatment 233798.0 -213000.0 -1.27 445744.0 -72000.0 -0.41 -1.1848 -0.8904 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C23 compound treatment 519080.0 72600.0 0.43 160482.0 -357000.0 -2.03 -1.1313 -0.5447 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 C24 compound treatment 261986.0 -185000.0 -1.1 461686.0 -56100.0 -0.32 -1.002 -0.8762 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D01 compound treatment 314178.0 -132000.0 -0.79 389988.0 -128000.0 -0.73 -1.0707 -0.9992 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D02 compound treatment 445392.0 -1140.0 -0.01 479149.0 -38600.0 -0.22 -0.16 -0.7285 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D03 compound treatment 345697.0 -101000.0 -0.6 239505.0 -278000.0 -1.58 -1.5432 -0.9119 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D04 compound treatment 129878.0 -317000.0 -1.88 158828.0 -359000.0 -2.04 -2.7758 -0.9992 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D05 compound treatment 438949.0 -7580.0 -0.05 474513.0 -43200.0 -0.25 -0.2058 -0.8231 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D06 compound treatment 435884.0 -10600.0 -0.06 467964.0 -49800.0 -0.28 -0.245 -0.8444 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D07 compound treatment 464419.0 17900.0 0.11 425117.0 -92600.0 -0.53 -0.2972 -0.553 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D08 compound treatment 413964.0 -32600.0 -0.19 448807.0 -68900.0 -0.39 -0.4143 -0.9472 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D09 compound treatment 431137.0 -15400.0 -0.09 458185.0 -59600.0 -0.34 -0.3043 -0.8672 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D10 compound treatment 422170.0 -24400.0 -0.14 409201.0 -109000.0 -0.62 -0.539 -0.85 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D11 mock treatment 425783.0 -20700.0 -0.12 461886.0 -55900.0 -0.32 -0.3119 -0.9152 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D12 mock treatment 396755.0 -49800.0 -0.3 453981.0 -63800.0 -0.36 -0.4659 -0.995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D13 compound treatment 412459.0 -34100.0 -0.2 467332.0 -50400.0 -0.29 -0.3461 -0.9856 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D14 compound treatment 76358.0 -370000.0 -2.2 80394.0 -437000.0 -2.49 -3.3165 -0.9982 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D15 mock treatment 390750.0 -55800.0 -0.33 197801.0 -320000.0 -1.82 -1.5213 -0.8225 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D16 mock treatment 402256.0 -44300.0 -0.26 449199.0 -68600.0 -0.39 -0.462 -0.9818 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D17 compound treatment 418455.0 -28100.0 -0.17 423997.0 -93800.0 -0.53 -0.4951 -0.8862 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D18 compound treatment 405692.0 -40800.0 -0.24 285553.0 -232000.0 -1.32 -1.1055 -0.8234 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D19 compound treatment 429055.0 -17500.0 -0.1 561068.0 43300.0 0.25 0.1007 0.3764 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D20 compound treatment 378982.0 -67500.0 -0.4 431517.0 -86200.0 -0.49 -0.631 -0.9951 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D21 compound treatment 160970.0 -286000.0 -1.7 457497.0 -60300.0 -0.34 -1.444 -0.8329 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D22 compound treatment 135020.0 -312000.0 -1.85 420782.0 -97000.0 -0.55 -1.7008 -0.8794 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D23 compound treatment 151386.0 -295000.0 -1.76 395478.0 -122000.0 -0.7 -1.7337 -0.9177 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 D24 compound treatment 321080.0 -125000.0 -0.75 467014.0 -50700.0 -0.29 -0.7319 -0.9145 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E01 mock treatment 493603.0 47100.0 0.28 585083.0 67300.0 0.38 0.4689 0.9882 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E02 mock treatment 364558.0 -82000.0 -0.49 511562.0 -6190.0 -0.04 -0.3698 -0.7562 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E03 compound treatment 475797.0 29300.0 0.17 571735.0 54000.0 0.31 0.3403 0.964 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E04 compound treatment 414327.0 -32200.0 -0.19 423737.0 -94000.0 -0.53 -0.5136 -0.9042 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E05 compound treatment 458617.0 12100.0 0.07 535788.0 18000.0 0.1 0.1234 0.985 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E06 compound treatment 420001.0 -26500.0 -0.16 485557.0 -32200.0 -0.18 -0.2411 -0.9973 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E07 compound treatment 430897.0 -15600.0 -0.09 482927.0 -34800.0 -0.2 -0.2058 -0.9406 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E08 compound treatment 414229.0 -32300.0 -0.19 463686.0 -54100.0 -0.31 -0.3533 -0.9744 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E09 mock treatment 423155.0 -23400.0 -0.14 484327.0 -33400.0 -0.19 -0.2328 -0.9882 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E10 mock treatment 407559.0 -39000.0 -0.23 400209.0 -118000.0 -0.67 -0.6366 -0.8998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E11 compound treatment 42544.0 -404000.0 -2.4 80619.0 -437000.0 -2.49 -3.4578 -0.9999 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E12 compound treatment 166050.0 -280000.0 -1.67 487683.0 -30100.0 -0.17 -1.3012 -0.7755 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E13 compound treatment 242731.0 -204000.0 -1.21 485080.0 -32700.0 -0.19 -0.989 -0.806 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E14 compound treatment 479930.0 33400.0 0.2 416987.0 -101000.0 -0.57 -0.2646 -0.4363 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E15 compound treatment 204131.0 -242000.0 -1.44 240018.0 -278000.0 -1.58 -2.1369 -0.999 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E16 compound treatment 400193.0 -46300.0 -0.28 440727.0 -77000.0 -0.44 -0.5047 -0.9751 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E17 mock treatment 410568.0 -36000.0 -0.21 496320.0 -21400.0 -0.12 -0.2375 -0.9644 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E18 mock treatment 417481.0 -29000.0 -0.17 192842.0 -325000.0 -1.85 -1.4287 -0.7699 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E19 compound treatment 126699.0 -320000.0 -1.9 310809.0 -207000.0 -1.18 -2.1781 -0.9733 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E20 compound treatment 165870.0 -281000.0 -1.67 441440.0 -76300.0 -0.43 -1.4879 -0.8622 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E21 compound treatment 125128.0 -321000.0 -1.91 183318.0 -334000.0 -1.9 -2.6973 -1.0 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E22 compound treatment 492054.0 45500.0 0.27 228119.0 -290000.0 -1.65 -0.9731 -0.583 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E23 compound treatment 299962.0 -147000.0 -0.87 223689.0 -294000.0 -1.67 -1.7993 -0.954 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 E24 compound treatment 468962.0 22400.0 0.13 446285.0 -71500.0 -0.41 -0.193 -0.4511 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F01 mock treatment 511649.0 65100.0 0.39 568297.0 50500.0 0.29 0.4773 0.9892 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F02 mock treatment 439681.0 -6850.0 -0.04 489953.0 -27800.0 -0.16 -0.1406 -0.8612 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F03 compound treatment 420138.0 -26400.0 -0.16 574548.0 56800.0 0.32 0.1173 0.3267 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F04 compound treatment 444571.0 -1960.0 -0.01 609155.0 91400.0 0.52 0.3593 0.6911 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F05 compound treatment 487042.0 40500.0 0.24 580080.0 62300.0 0.35 0.4211 0.9824 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F06 compound treatment 484095.0 37600.0 0.22 518251.0 500.0 0.0 0.1601 0.716 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F07 compound treatment 481959.0 35400.0 0.21 581319.0 63600.0 0.36 0.4047 0.9671 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F08 compound treatment 376052.0 -70500.0 -0.42 466258.0 -51500.0 -0.29 -0.5036 -0.9846 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F09 mock treatment 433708.0 -12800.0 -0.08 485551.0 -32200.0 -0.18 -0.1834 -0.9247 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F10 mock treatment 413876.0 -32700.0 -0.19 553564.0 35800.0 0.2 0.0066 0.0235 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F11 compound treatment 465093.0 18600.0 0.11 533997.0 16200.0 0.09 0.1435 0.996 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F12 compound treatment 389211.0 -57300.0 -0.34 430503.0 -87200.0 -0.5 -0.592 -0.9833 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F13 compound treatment 478942.0 32400.0 0.19 461017.0 -56700.0 -0.32 -0.0917 -0.244 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F14 compound treatment 403016.0 -43500.0 -0.26 482513.0 -35200.0 -0.2 -0.3248 -0.992 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F15 compound treatment 425833.0 -20700.0 -0.12 529794.0 12000.0 0.07 -0.0387 -0.2743 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F16 compound treatment 117704.0 -329000.0 -1.96 141330.0 -376000.0 -2.14 -2.8974 -0.999 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F17 mock treatment 362297.0 -84200.0 -0.5 493526.0 -24200.0 -0.14 -0.4519 -0.8692 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F18 mock treatment 442687.0 -3840.0 -0.02 465253.0 -52500.0 -0.3 -0.2273 -0.759 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F19 compound treatment 418576.0 -28000.0 -0.17 442507.0 -75200.0 -0.43 -0.4202 -0.9153 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F20 compound treatment 398606.0 -47900.0 -0.29 216492.0 -301000.0 -1.71 -1.4131 -0.8136 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F21 compound treatment 370677.0 -75900.0 -0.45 252662.0 -265000.0 -1.51 -1.3852 -0.8802 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F22 compound treatment 421159.0 -25400.0 -0.15 412163.0 -106000.0 -0.6 -0.5313 -0.8582 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F23 compound treatment 462793.0 16300.0 0.1 438769.0 -79000.0 -0.45 -0.2491 -0.5423 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 F24 compound treatment 445681.0 -846.0 -0.01 427767.0 -90000.0 -0.51 -0.3654 -0.714 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G01 compound treatment 457561.0 11000.0 0.07 521297.0 3550.0 0.02 0.0607 0.8835 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G02 compound treatment 374123.0 -72400.0 -0.43 493327.0 -24400.0 -0.14 -0.4029 -0.8899 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G03 mock treatment 488743.0 42200.0 0.25 603416.0 85700.0 0.49 0.5221 0.9526 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G04 mock treatment 455796.0 9270.0 0.06 523450.0 5700.0 0.03 0.0619 0.9679 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G05 compound treatment 443558.0 -2970.0 -0.02 550712.0 33000.0 0.19 0.12 0.6376 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G06 compound treatment 456318.0 9790.0 0.06 535314.0 17600.0 0.1 0.1118 0.9671 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G07 compound treatment 241575.0 -205000.0 -1.22 281781.0 -236000.0 -1.34 -1.8114 -0.9989 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G08 compound treatment 505539.0 59000.0 0.35 562783.0 45000.0 0.26 0.4294 0.988 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G09 compound treatment 416590.0 -29900.0 -0.18 630576.0 113000.0 0.64 0.3277 0.4921 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G10 compound treatment 431316.0 -15200.0 -0.09 524762.0 7010.0 0.04 -0.0358 -0.3621 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G11 compound treatment 474188.0 27700.0 0.16 446098.0 -71700.0 -0.41 -0.1717 -0.3908 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G12 compound treatment 425656.0 -20900.0 -0.12 380005.0 -138000.0 -0.78 -0.6417 -0.8091 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G13 compound treatment 260856.0 -186000.0 -1.11 427027.0 -90700.0 -0.52 -1.1462 -0.9399 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G14 compound treatment 277881.0 -169000.0 -1.0 460844.0 -56900.0 -0.32 -0.9385 -0.89 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G15 compound treatment 119116.0 -327000.0 -1.95 129739.0 -388000.0 -2.21 -2.9381 -0.9981 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G16 compound treatment 442469.0 -4060.0 -0.02 468906.0 -48800.0 -0.28 -0.2135 -0.7657 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G17 compound treatment 595763.0 149000.0 0.89 564658.0 46900.0 0.27 0.8166 0.8806 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G18 compound treatment 417164.0 -29400.0 -0.17 544197.0 26400.0 0.15 -0.0172 -0.0747 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G19 mock treatment 172397.0 -274000.0 -1.63 148881.0 -369000.0 -2.1 -2.6369 -0.9923 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G20 mock treatment 438177.0 -8350.0 -0.05 456827.0 -60900.0 -0.35 -0.2801 -0.8003 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G21 compound treatment 107482.0 -339000.0 -2.02 74570.0 -443000.0 -2.52 -3.2089 -0.9939 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G22 compound treatment 416695.0 -29800.0 -0.18 517272.0 -479.0 0.0 -0.1275 -0.7179 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G23 compound treatment 454027.0 7500.0 0.04 611993.0 94200.0 0.54 0.4105 0.7634 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 G24 compound treatment 490401.0 43900.0 0.26 227665.0 -290000.0 -1.65 -0.9818 -0.5879 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H01 compound treatment 530168.0 83600.0 0.5 598209.0 80500.0 0.46 0.6755 0.9991 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H02 compound treatment 449028.0 2500.0 0.01 354209.0 -164000.0 -0.93 -0.6471 -0.6957 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H03 mock treatment 390725.0 -55800.0 -0.33 569996.0 52200.0 0.3 -0.0247 -0.0555 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H04 mock treatment 465569.0 19000.0 0.11 552418.0 34700.0 0.2 0.2195 0.9654 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H05 compound treatment 393405.0 -53100.0 -0.32 493743.0 -24000.0 -0.14 -0.3201 -0.9295 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H06 compound treatment 345883.0 -101000.0 -0.6 524352.0 6600.0 0.04 -0.397 -0.6615 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H07 compound treatment 123255.0 -323000.0 -1.92 211680.0 -306000.0 -1.74 -2.5912 -0.9988 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H08 compound treatment 415699.0 -30800.0 -0.18 471627.0 -46100.0 -0.26 -0.3152 -0.9847 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H09 compound treatment 381945.0 -64600.0 -0.38 509430.0 -8320.0 -0.05 -0.3052 -0.7882 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H10 compound treatment 486620.0 40100.0 0.24 551160.0 33400.0 0.19 0.3031 0.9936 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H11 compound treatment 429120.0 -17400.0 -0.1 553093.0 35300.0 0.2 0.0689 0.3045 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H12 compound treatment 458563.0 12000.0 0.07 704582.0 187000.0 1.06 0.8019 0.7531 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H13 compound treatment 447709.0 1180.0 0.01 190554.0 -327000.0 -1.86 -1.3107 -0.7044 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H14 compound treatment 473679.0 27200.0 0.16 488515.0 -29200.0 -0.17 -0.0033 -0.0142 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H15 compound treatment 415998.0 -30500.0 -0.18 273206.0 -245000.0 -1.39 -1.1118 -0.7928 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H16 compound treatment 358126.0 -88400.0 -0.53 287262.0 -230000.0 -1.31 -1.2988 -0.9196 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H17 compound treatment 82246.0 -364000.0 -2.17 129220.0 -389000.0 -2.21 -3.0953 -1.0 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H18 compound treatment 382632.0 -63900.0 -0.38 423283.0 -94500.0 -0.54 -0.6488 -0.9857 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H19 mock treatment 293791.0 -153000.0 -0.91 208904.0 -309000.0 -1.76 -1.8847 -0.953 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H20 mock treatment 427051.0 -19500.0 -0.12 213330.0 -304000.0 -1.73 -1.3061 -0.7528 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H21 compound treatment 508297.0 61800.0 0.37 465667.0 -52100.0 -0.3 0.0505 0.107 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H22 compound treatment 475725.0 29200.0 0.17 474477.0 -43300.0 -0.25 -0.0511 -0.1698 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H23 compound treatment 543516.0 97000.0 0.58 438422.0 -79300.0 -0.45 0.0892 0.1217 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 H24 compound treatment 586424.0 140000.0 0.83 112802.0 -405000.0 -2.3 -1.0396 -0.4246 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I01 compound treatment 484384.0 37900.0 0.23 553811.0 36100.0 0.21 0.3043 0.9989 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I02 compound treatment 401092.0 -45400.0 -0.27 561037.0 43300.0 0.25 -0.0171 -0.0469 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I03 compound treatment 425203.0 -21300.0 -0.13 531251.0 13500.0 0.08 -0.0355 -0.239 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I04 compound treatment 446705.0 178.0 0.0 511799.0 -5950.0 -0.03 -0.0232 -0.6847 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I05 mock treatment 411048.0 -35500.0 -0.21 522208.0 4460.0 0.03 -0.1314 -0.6178 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I06 mock treatment 428192.0 -18300.0 -0.11 481185.0 -36600.0 -0.21 -0.2242 -0.9547 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I07 compound treatment 395848.0 -50700.0 -0.3 498694.0 -19100.0 -0.11 -0.2899 -0.9046 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I08 compound treatment 439532.0 -7000.0 -0.04 589146.0 71400.0 0.41 0.2577 0.6313 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I09 compound treatment 374335.0 -72200.0 -0.43 426353.0 -91400.0 -0.52 -0.6713 -0.9955 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I10 compound treatment 427004.0 -19500.0 -0.12 516303.0 -1450.0 -0.01 -0.088 -0.7553 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I11 compound treatment 398729.0 -47800.0 -0.28 471532.0 -46200.0 -0.26 -0.387 -0.9992 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I12 compound treatment 463392.0 16900.0 0.1 532224.0 14500.0 0.08 0.1292 0.9951 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I13 compound treatment 393629.0 -52900.0 -0.31 514981.0 -2770.0 -0.02 -0.2338 -0.7416 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I14 compound treatment 465564.0 19000.0 0.11 506200.0 -11600.0 -0.07 0.0337 0.257 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I15 compound treatment 427832.0 -18700.0 -0.11 541330.0 23600.0 0.13 0.0161 0.0926 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I16 compound treatment 445443.0 -1080.0 -0.01 441677.0 -76100.0 -0.43 -0.3105 -0.7176 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I17 compound treatment 446685.0 158.0 0.0 459764.0 -58000.0 -0.33 -0.2325 -0.7051 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I18 compound treatment 406129.0 -40400.0 -0.24 525189.0 7440.0 0.04 -0.1401 -0.5739 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I19 compound treatment 127779.0 -319000.0 -1.9 156275.0 -361000.0 -2.06 -2.7949 -0.9992 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I20 compound treatment 451798.0 5270.0 0.03 490020.0 -27700.0 -0.16 -0.0893 -0.5556 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I21 mock treatment 423672.0 -22900.0 -0.14 468937.0 -48800.0 -0.28 -0.2925 -0.9461 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I22 mock treatment 521100.0 74600.0 0.44 429947.0 -87800.0 -0.5 -0.0392 -0.0588 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I23 compound treatment 487035.0 40500.0 0.24 276275.0 -241000.0 -1.37 -0.8005 -0.5742 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 I24 compound treatment 458998.0 12500.0 0.07 483444.0 -34300.0 -0.2 -0.0855 -0.4095 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J01 compound treatment 470072.0 23500.0 0.14 597259.0 79500.0 0.45 0.4188 0.8847 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J02 compound treatment 373616.0 -72900.0 -0.43 555769.0 38000.0 0.22 -0.154 -0.3176 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J03 compound treatment 419383.0 -27100.0 -0.16 544280.0 26500.0 0.15 -0.0076 -0.0342 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J04 compound treatment 384465.0 -62100.0 -0.37 559779.0 42000.0 0.24 -0.0922 -0.2095 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J05 mock treatment 410531.0 -36000.0 -0.21 472567.0 -45200.0 -0.26 -0.3332 -0.9959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J06 mock treatment 419942.0 -26600.0 -0.16 506021.0 -11700.0 -0.07 -0.159 -0.9263 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J07 compound treatment 441974.0 -4550.0 -0.03 507700.0 -10100.0 -0.06 -0.0596 -0.9419 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J08 compound treatment 417496.0 -29000.0 -0.17 497419.0 -20300.0 -0.12 -0.2039 -0.9809 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J09 compound treatment 443723.0 -2800.0 -0.02 507144.0 -10600.0 -0.06 -0.0545 -0.8701 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J10 compound treatment 473939.0 27400.0 0.16 547595.0 29800.0 0.17 0.2354 0.9998 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J11 compound treatment 482371.0 35800.0 0.21 533118.0 15400.0 0.09 0.2126 0.9224 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J12 compound treatment 327847.0 -119000.0 -0.71 266007.0 -252000.0 -1.43 -1.5117 -0.947 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J13 compound treatment 459508.0 13000.0 0.08 411802.0 -106000.0 -0.6 -0.3714 -0.6114 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J14 compound treatment 451886.0 5360.0 0.03 425331.0 -92400.0 -0.53 -0.3491 -0.663 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J15 compound treatment 437185.0 -9340.0 -0.06 520828.0 3080.0 0.02 -0.0269 -0.4622 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J16 compound treatment 426345.0 -20200.0 -0.12 562925.0 45200.0 0.26 0.0967 0.3411 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J17 compound treatment 422460.0 -24100.0 -0.14 195627.0 -322000.0 -1.83 -1.3966 -0.7601 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J18 compound treatment 429545.0 -17000.0 -0.1 459936.0 -57800.0 -0.33 -0.3039 -0.8837 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J19 compound treatment 485889.0 39400.0 0.23 575981.0 58200.0 0.33 0.3998 0.9856 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J20 compound treatment 450335.0 3810.0 0.02 275029.0 -243000.0 -1.38 -0.96 -0.6954 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J21 mock treatment 508355.0 61800.0 0.37 471430.0 -46300.0 -0.26 0.0739 0.1634 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J22 mock treatment 491511.0 45000.0 0.27 422510.0 -95200.0 -0.54 -0.1937 -0.3206 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J23 compound treatment 154218.0 -292000.0 -1.74 405358.0 -112000.0 -0.64 -1.6821 -0.9076 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 J24 compound treatment 501701.0 55200.0 0.33 480103.0 -37600.0 -0.21 0.0808 0.2061 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K01 compound treatment 475555.0 29000.0 0.17 443125.0 -74600.0 -0.42 -0.1779 -0.3883 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K02 compound treatment 223941.0 -223000.0 -1.32 550657.0 32900.0 0.19 -0.8044 -0.6013 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K03 compound treatment 266210.0 -180000.0 -1.07 559893.0 42100.0 0.24 -0.5894 -0.536 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K04 compound treatment 458796.0 12300.0 0.07 588653.0 70900.0 0.4 0.3367 0.8218 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K05 compound treatment 485371.0 38800.0 0.23 549922.0 32200.0 0.18 0.2928 0.9933 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K06 compound treatment 417747.0 -28800.0 -0.17 608876.0 91100.0 0.52 0.2453 0.4495 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K07 mock treatment 509134.0 62600.0 0.37 542182.0 24400.0 0.14 0.3617 0.9096 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K08 mock treatment 497119.0 50600.0 0.3 582336.0 64600.0 0.37 0.4726 0.9951 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K09 compound treatment 349306.0 -97200.0 -0.58 459245.0 -58500.0 -0.33 -0.6444 -0.9655 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K10 compound treatment 469257.0 22700.0 0.14 527403.0 9650.0 0.05 0.1345 0.9211 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K11 compound treatment 543772.0 97200.0 0.58 531241.0 13500.0 0.08 0.4635 0.7939 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K12 compound treatment 472333.0 25800.0 0.15 464858.0 -52900.0 -0.3 -0.1041 -0.3082 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K13 compound treatment 551205.0 105000.0 0.62 556308.0 38600.0 0.22 0.5956 0.9018 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K14 compound treatment 508986.0 62500.0 0.37 504866.0 -12900.0 -0.07 0.211 0.557 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K15 mock treatment 501954.0 55400.0 0.33 563860.0 46100.0 0.26 0.4187 0.9935 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K16 mock treatment 195104.0 -251000.0 -1.5 596092.0 78300.0 0.45 -0.743 -0.4759 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K17 compound treatment 484744.0 38200.0 0.23 562219.0 44500.0 0.25 0.3396 0.9986 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K18 compound treatment 423752.0 -22800.0 -0.14 575148.0 57400.0 0.33 0.135 0.3818 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K19 compound treatment 237421.0 -209000.0 -1.24 397277.0 -120000.0 -0.69 -1.3644 -0.9605 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K20 compound treatment 464205.0 17700.0 0.11 609585.0 91800.0 0.52 0.4437 0.8328 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K21 compound treatment 63470.0 -383000.0 -2.28 71019.0 -447000.0 -2.54 -3.4084 -0.9985 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K22 compound treatment 476441.0 29900.0 0.18 476787.0 -41000.0 -0.23 -0.0388 -0.1325 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K23 mock treatment 528972.0 82400.0 0.49 456272.0 -61500.0 -0.35 0.0997 0.1655 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 K24 mock treatment 531487.0 85000.0 0.51 536627.0 18900.0 0.11 0.4334 0.8385 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L01 compound treatment 508784.0 62300.0 0.37 601061.0 83300.0 0.47 0.597 0.9926 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L02 compound treatment 202816.0 -244000.0 -1.45 590040.0 72300.0 0.41 -0.7349 -0.4875 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L03 compound treatment 509588.0 63100.0 0.38 565131.0 47400.0 0.27 0.4559 0.9868 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L04 compound treatment 374625.0 -71900.0 -0.43 418952.0 -98800.0 -0.56 -0.6999 -0.991 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L05 compound treatment 306053.0 -140000.0 -0.84 586697.0 68900.0 0.39 -0.3139 -0.34 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L06 compound treatment 463086.0 16600.0 0.1 504331.0 -13400.0 -0.08 0.0157 0.1261 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L07 mock treatment 484004.0 37500.0 0.22 580788.0 63000.0 0.36 0.4112 0.9739 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L08 mock treatment 457015.0 10500.0 0.06 555695.0 37900.0 0.22 0.1967 0.8757 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L09 compound treatment 480674.0 34100.0 0.2 558883.0 41100.0 0.23 0.3091 0.9975 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L10 compound treatment 481765.0 35200.0 0.21 547939.0 30200.0 0.17 0.2697 0.9951 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L11 compound treatment 544239.0 97700.0 0.58 577500.0 59700.0 0.34 0.6515 0.9673 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L12 compound treatment 302802.0 -144000.0 -0.86 388628.0 -129000.0 -0.73 -1.1241 -0.9971 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L13 compound treatment 491718.0 45200.0 0.27 564800.0 47000.0 0.27 0.3794 1.0 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L14 compound treatment 472749.0 26200.0 0.16 590896.0 73100.0 0.42 0.4045 0.9104 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L15 mock treatment 462448.0 15900.0 0.09 573991.0 56200.0 0.32 0.2931 0.8788 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L16 mock treatment 489107.0 42600.0 0.25 548603.0 30900.0 0.18 0.3032 0.9839 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L17 compound treatment 171408.0 -275000.0 -1.64 543324.0 25600.0 0.15 -1.0549 -0.6418 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L18 compound treatment 460399.0 13900.0 0.08 519081.0 1330.0 0.01 0.0637 0.7687 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L19 compound treatment 453563.0 7040.0 0.04 569636.0 51900.0 0.3 0.2382 0.7994 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L20 compound treatment 472730.0 26200.0 0.16 540215.0 22500.0 0.13 0.2006 0.9951 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L21 compound treatment 477802.0 31300.0 0.19 504661.0 -13100.0 -0.07 0.079 0.394 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L22 compound treatment 468070.0 21500.0 0.13 442363.0 -75400.0 -0.43 -0.2125 -0.4749 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L23 mock treatment 478912.0 32400.0 0.19 291608.0 -226000.0 -1.29 -0.7731 -0.5945 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 L24 mock treatment 533771.0 87200.0 0.52 514894.0 -2860.0 -0.02 0.3557 0.6846 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M01 compound treatment 488809.0 42300.0 0.25 633271.0 116000.0 0.66 0.6425 0.9133 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M02 compound treatment 236214.0 -210000.0 -1.25 277240.0 -241000.0 -1.37 -1.8522 -0.999 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M03 compound treatment 512307.0 65800.0 0.39 594269.0 76500.0 0.44 0.5845 0.9986 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M04 compound treatment 570107.0 124000.0 0.74 590918.0 73200.0 0.42 0.8143 0.9636 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M05 compound treatment 579640.0 133000.0 0.79 586199.0 68400.0 0.39 0.8354 0.9465 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M06 compound treatment 465071.0 18500.0 0.11 574221.0 56500.0 0.32 0.3051 0.8985 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M07 compound treatment 341773.0 -105000.0 -0.62 405352.0 -112000.0 -0.64 -0.8928 -0.9999 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M08 compound treatment 491976.0 45400.0 0.27 593148.0 75400.0 0.43 0.4944 0.9753 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M09 mock treatment 484208.0 37700.0 0.22 599546.0 81800.0 0.47 0.4875 0.944 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M10 mock treatment 479090.0 32600.0 0.19 639177.0 121000.0 0.69 0.6253 0.8719 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M11 compound treatment 90646.0 -356000.0 -2.12 100138.0 -418000.0 -2.37 -3.1769 -0.9984 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M12 compound treatment 488882.0 42400.0 0.25 540514.0 22800.0 0.13 0.2698 0.952 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M13 mock treatment 485419.0 38900.0 0.23 597067.0 79300.0 0.45 0.4826 0.9519 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M14 mock treatment 554404.0 108000.0 0.64 624471.0 107000.0 0.61 0.8831 0.9996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M15 compound treatment 188114.0 -258000.0 -1.54 286750.0 -231000.0 -1.31 -2.0164 -0.9969 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M16 compound treatment 487408.0 40900.0 0.24 550996.0 33200.0 0.19 0.3057 0.9922 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M17 compound treatment 491921.0 45400.0 0.27 545233.0 27500.0 0.16 0.3015 0.9661 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M18 compound treatment 462142.0 15600.0 0.09 621100.0 103000.0 0.59 0.4813 0.8089 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M19 compound treatment 164593.0 -282000.0 -1.68 164742.0 -353000.0 -2.01 -2.606 -0.996 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M20 compound treatment 539044.0 92500.0 0.55 686218.0 168000.0 0.96 1.0668 0.9654 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M21 compound treatment 554338.0 108000.0 0.64 601922.0 84200.0 0.48 0.7922 0.9896 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M22 compound treatment 434301.0 -12200.0 -0.07 512534.0 -5220.0 -0.03 -0.0724 -0.9217 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M23 compound treatment 518155.0 71600.0 0.43 518719.0 968.0 0.01 0.3053 0.7162 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 M24 compound treatment 561368.0 115000.0 0.68 637569.0 120000.0 0.68 0.9651 1.0 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N01 compound treatment 492639.0 46100.0 0.27 643826.0 126000.0 0.72 0.701 0.9132 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N02 compound treatment 436887.0 -9640.0 -0.06 592451.0 74700.0 0.42 0.2598 0.6061 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N03 compound treatment 529512.0 83000.0 0.49 652831.0 135000.0 0.77 0.8924 0.9772 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N04 compound treatment 397845.0 -48700.0 -0.29 598124.0 80400.0 0.46 0.1183 0.2186 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N05 compound treatment 530715.0 84200.0 0.5 579478.0 61700.0 0.35 0.6025 0.9849 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N06 compound treatment 506337.0 59800.0 0.36 549534.0 31800.0 0.18 0.3795 0.9506 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N07 compound treatment 461951.0 15400.0 0.09 545805.0 28100.0 0.16 0.1777 0.9655 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N08 compound treatment 457479.0 11000.0 0.07 527764.0 10000.0 0.06 0.0864 0.9977 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N09 mock treatment 464675.0 18100.0 0.11 219092.0 -299000.0 -1.7 -1.1246 -0.6608 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N10 mock treatment 481734.0 35200.0 0.21 600677.0 82900.0 0.47 0.4816 0.9333 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N11 compound treatment 433952.0 -12600.0 -0.07 577917.0 60200.0 0.34 0.189 0.5397 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N12 compound treatment 390808.0 -55700.0 -0.33 477434.0 -40300.0 -0.23 -0.3966 -0.9838 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N13 mock treatment 493732.0 47200.0 0.28 584132.0 66400.0 0.38 0.4656 0.9894 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N14 mock treatment 496474.0 49900.0 0.3 594084.0 76300.0 0.43 0.5171 0.9829 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N15 compound treatment 483850.0 37300.0 0.22 583913.0 66200.0 0.38 0.4231 0.9684 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N16 compound treatment 464709.0 18200.0 0.11 596633.0 78900.0 0.45 0.3937 0.8532 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N17 compound treatment 530809.0 84300.0 0.5 564992.0 47200.0 0.27 0.5446 0.9572 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N18 compound treatment 501501.0 55000.0 0.33 601910.0 84200.0 0.48 0.5698 0.9828 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N19 compound treatment 512712.0 66200.0 0.39 598683.0 80900.0 0.46 0.604 0.997 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N20 compound treatment 534014.0 87500.0 0.52 544858.0 27100.0 0.15 0.4772 0.8788 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N21 compound treatment 499877.0 53300.0 0.32 476400.0 -41400.0 -0.24 0.0582 0.1474 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N22 compound treatment 478498.0 32000.0 0.19 575683.0 57900.0 0.33 0.3675 0.966 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N23 compound treatment 460018.0 13500.0 0.08 495723.0 -22000.0 -0.13 -0.0318 -0.2138 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 N24 compound treatment 517197.0 70700.0 0.42 567976.0 50200.0 0.29 0.4994 0.9822 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O01 compound treatment 502222.0 55700.0 0.33 565823.0 48100.0 0.27 0.4277 0.9954 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O02 compound treatment 223098.0 -223000.0 -1.33 205610.0 -312000.0 -1.78 -2.1954 -0.9899 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O03 compound treatment 482804.0 36300.0 0.22 532762.0 15000.0 0.09 0.213 0.9176 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O04 compound treatment 512211.0 65700.0 0.39 611465.0 93700.0 0.53 0.6533 0.9884 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O05 compound treatment 587746.0 141000.0 0.84 591241.0 73500.0 0.42 0.8898 0.948 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O06 compound treatment 424276.0 -22300.0 -0.13 556109.0 38400.0 0.22 0.0606 0.2375 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O07 compound treatment 334072.0 -112000.0 -0.67 538967.0 21200.0 0.12 -0.3879 -0.5704 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O08 compound treatment 497578.0 51100.0 0.3 564104.0 46400.0 0.26 0.4012 0.9975 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O09 compound treatment 481308.0 34800.0 0.21 575746.0 58000.0 0.33 0.3796 0.9748 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O10 compound treatment 494327.0 47800.0 0.28 596732.0 79000.0 0.45 0.5187 0.9757 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O11 mock treatment 461637.0 15100.0 0.09 613069.0 95300.0 0.54 0.4469 0.8133 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O12 mock treatment 505243.0 58700.0 0.35 696151.0 178000.0 1.01 0.9645 0.8988 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O13 compound treatment 512442.0 65900.0 0.39 643291.0 126000.0 0.71 0.7822 0.9602 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O14 compound treatment 567263.0 121000.0 0.72 601097.0 83300.0 0.47 0.8432 0.9796 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O15 compound treatment 544881.0 98400.0 0.59 359459.0 -158000.0 -0.9 -0.2226 -0.2073 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O16 compound treatment 538973.0 92400.0 0.55 658359.0 141000.0 0.8 0.9544 0.9834 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O17 compound treatment 548314.0 102000.0 0.61 609330.0 91600.0 0.52 0.7966 0.9972 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O18 compound treatment 526906.0 80400.0 0.48 615449.0 97700.0 0.56 0.7311 0.9972 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O19 compound treatment 134395.0 -312000.0 -1.86 67894.0 -450000.0 -2.56 -3.1225 -0.9876 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O20 compound treatment 564568.0 118000.0 0.7 652007.0 134000.0 0.76 1.0366 0.9991 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O21 compound treatment 154306.0 -292000.0 -1.74 188517.0 -329000.0 -1.87 -2.5536 -0.9993 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O22 compound treatment 541783.0 95300.0 0.57 641332.0 124000.0 0.7 0.8978 0.9943 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O23 compound treatment 473570.0 27000.0 0.16 162256.0 -355000.0 -2.02 -1.3157 -0.6488 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 O24 compound treatment 487029.0 40500.0 0.24 567853.0 50100.0 0.28 0.3719 0.9965 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P01 compound treatment 415671.0 -30900.0 -0.18 482056.0 -35700.0 -0.2 -0.2734 -0.9988 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P02 compound treatment 363303.0 -83200.0 -0.5 462258.0 -55500.0 -0.32 -0.5734 -0.9763 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P03 compound treatment 461908.0 15400.0 0.09 539241.0 21500.0 0.12 0.1511 0.9899 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P04 compound treatment 416256.0 -30300.0 -0.18 570524.0 52800.0 0.3 0.0848 0.2423 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P05 compound treatment 464288.0 17800.0 0.11 528122.0 10400.0 0.06 0.1164 0.962 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P06 compound treatment 445576.0 -951.0 -0.01 570996.0 53200.0 0.3 0.2101 0.6938 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P07 compound treatment 397366.0 -49200.0 -0.29 559501.0 41700.0 0.24 -0.039 -0.1035 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P08 compound treatment 441539.0 -4990.0 -0.03 580682.0 62900.0 0.36 0.2321 0.6462 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P09 compound treatment 527155.0 80600.0 0.48 592528.0 74800.0 0.43 0.64 0.9982 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P10 compound treatment 506273.0 59700.0 0.36 599823.0 82100.0 0.47 0.5814 0.991 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P11 mock treatment 461900.0 15400.0 0.09 402254.0 -115000.0 -0.66 -0.3997 -0.6028 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P12 mock treatment 512660.0 66100.0 0.39 545761.0 28000.0 0.16 0.3909 0.9207 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P13 compound treatment 501016.0 54500.0 0.32 651405.0 134000.0 0.76 0.7667 0.9279 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P14 compound treatment 491301.0 44800.0 0.27 559152.0 41400.0 0.24 0.3549 0.9981 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P15 compound treatment 406622.0 -39900.0 -0.24 525353.0 7600.0 0.04 -0.1374 -0.569 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P16 compound treatment 518897.0 72400.0 0.43 527778.0 10000.0 0.06 0.3449 0.7938 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P17 compound treatment 502516.0 56000.0 0.33 536841.0 19100.0 0.11 0.3124 0.8914 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P18 compound treatment 558681.0 112000.0 0.67 636290.0 119000.0 0.67 0.9486 1.0 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P19 compound treatment 511131.0 64600.0 0.38 335889.0 -182000.0 -1.03 -0.4594 -0.4164 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P20 compound treatment 466431.0 19900.0 0.12 554367.0 36600.0 0.21 0.231 0.9643 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P21 compound treatment 401997.0 -44500.0 -0.27 555623.0 37900.0 0.22 -0.0351 -0.1028 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P22 compound treatment 485485.0 39000.0 0.23 295597.0 -222000.0 -1.26 -0.7294 -0.5679 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P23 compound treatment 557161.0 111000.0 0.66 242056.0 -276000.0 -1.57 -0.643 -0.3782 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2100 P24 compound treatment 180037.0 -266000.0 -1.59 127420.0 -390000.0 -2.22 -2.691 -0.9864 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A01 compound treatment 236924.0 -67500.0 -0.4 533394.0 155000.0 0.88 0.3396 0.3504 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A02 compound treatment 278571.0 -25800.0 -0.15 426046.0 47700.0 0.27 0.0832 0.2667 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A03 compound treatment 297190.0 -7220.0 -0.04 476323.0 98000.0 0.56 0.3637 0.6507 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A04 compound treatment 430782.0 126000.0 0.75 433977.0 55700.0 0.32 0.7556 0.926 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A05 compound treatment 292859.0 -11600.0 -0.07 582409.0 204000.0 1.16 0.7721 0.6641 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A06 compound treatment 236997.0 -67400.0 -0.4 457756.0 79400.0 0.45 0.0357 0.0592 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A07 compound treatment 519082.0 215000.0 1.28 219881.0 -158000.0 -0.9 0.2663 0.1703 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A08 compound treatment 261666.0 -42700.0 -0.25 451411.0 73100.0 0.42 0.114 0.234 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A09 compound treatment 374958.0 70500.0 0.42 503298.0 125000.0 0.71 0.7995 0.9685 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A10 compound treatment 326141.0 21700.0 0.13 464418.0 86100.0 0.49 0.4377 0.8642 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A11 compound treatment 313562.0 9150.0 0.05 531995.0 154000.0 0.87 0.6565 0.7497 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A12 compound treatment 358686.0 54300.0 0.32 151119.0 -227000.0 -1.29 -0.6852 -0.5145 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A13 mock treatment 250092.0 -54300.0 -0.32 360811.0 -17500.0 -0.1 -0.299 -0.8839 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A14 mock treatment 222320.0 -82100.0 -0.49 329237.0 -49100.0 -0.28 -0.5428 -0.9647 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A15 compound treatment 520403.0 216000.0 1.29 427851.0 49500.0 0.28 1.1081 0.8421 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A16 compound treatment 323083.0 18700.0 0.11 351183.0 -27100.0 -0.15 -0.0305 -0.1605 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A17 compound treatment 278824.0 -25600.0 -0.15 254011.0 -124000.0 -0.71 -0.6075 -0.8402 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A18 compound treatment 524874.0 220000.0 1.31 257128.0 -121000.0 -0.69 0.4405 0.2972 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A19 compound treatment 256865.0 -47500.0 -0.28 486937.0 109000.0 0.62 0.2367 0.3484 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A20 compound treatment 394310.0 89900.0 0.54 392401.0 14100.0 0.08 0.435 0.804 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A21 compound treatment 571043.0 267000.0 1.59 546976.0 169000.0 0.96 1.8003 0.9709 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A22 compound treatment 391938.0 87500.0 0.52 274207.0 -104000.0 -0.59 -0.0503 -0.0638 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A23 compound treatment 209079.0 -95300.0 -0.57 420551.0 42200.0 0.24 -0.2313 -0.3755 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 A24 compound treatment 467357.0 163000.0 0.97 436056.0 57700.0 0.33 0.9179 0.8965 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B01 compound treatment 519959.0 216000.0 1.28 548861.0 171000.0 0.97 1.5929 0.9905 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B02 compound treatment 327269.0 22900.0 0.14 470646.0 92300.0 0.53 0.4675 0.8619 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B03 compound treatment 445700.0 141000.0 0.84 471931.0 93600.0 0.53 0.971 0.9757 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B04 compound treatment 304048.0 -363.0 0.0 537970.0 160000.0 0.91 0.6405 0.7054 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B05 compound treatment 450900.0 146000.0 0.87 484260.0 106000.0 0.6 1.0425 0.9837 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B06 compound treatment 448368.0 144000.0 0.86 469280.0 91000.0 0.52 0.9716 0.9708 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B07 compound treatment 443453.0 139000.0 0.83 453956.0 75600.0 0.43 0.8893 0.9535 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B08 compound treatment 435241.0 131000.0 0.78 444063.0 65700.0 0.37 0.815 0.9435 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B09 compound treatment 486110.0 182000.0 1.08 513736.0 135000.0 0.77 1.3092 0.9862 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B10 compound treatment 443927.0 140000.0 0.83 470982.0 92700.0 0.53 0.9597 0.9759 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B11 compound treatment 504715.0 200000.0 1.19 492353.0 114000.0 0.65 1.3015 0.959 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B12 compound treatment 451359.0 147000.0 0.87 473199.0 94900.0 0.54 0.9999 0.9731 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B13 mock treatment 449039.0 145000.0 0.86 453792.0 75500.0 0.43 0.9121 0.9483 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B14 mock treatment 405515.0 101000.0 0.6 481222.0 103000.0 0.59 0.8393 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B15 compound treatment 462925.0 159000.0 0.94 453972.0 75700.0 0.43 0.9713 0.9368 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B16 compound treatment 482223.0 178000.0 1.06 414025.0 35700.0 0.2 0.8919 0.8277 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B17 compound treatment 459899.0 155000.0 0.93 396304.0 18000.0 0.1 0.7267 0.7805 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B18 compound treatment 479856.0 175000.0 1.04 449249.0 70900.0 0.4 1.0236 0.9144 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B19 compound treatment 522796.0 218000.0 1.3 516293.0 138000.0 0.78 1.4739 0.9708 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B20 compound treatment 207994.0 -96400.0 -0.57 553238.0 175000.0 0.99 0.2976 0.2592 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B21 compound treatment 471889.0 167000.0 1.0 407977.0 29700.0 0.17 0.8241 0.8152 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B22 compound treatment 484313.0 180000.0 1.07 466526.0 88200.0 0.5 1.1118 0.9403 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B23 compound treatment 689505.0 385000.0 2.29 699111.0 321000.0 1.82 2.9106 0.9936 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 B24 compound treatment 591502.0 287000.0 1.71 497198.0 119000.0 0.68 1.6862 0.9177 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C01 compound treatment 457068.0 153000.0 0.91 468927.0 90600.0 0.52 1.0068 0.9639 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C02 compound treatment 298258.0 -6150.0 -0.04 510570.0 132000.0 0.75 0.5059 0.6719 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C03 compound treatment 474368.0 170000.0 1.01 515913.0 138000.0 0.78 1.2685 0.992 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C04 compound treatment 330361.0 25900.0 0.15 574227.0 196000.0 1.11 0.897 0.7975 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C05 compound treatment 434670.0 130000.0 0.78 446593.0 68300.0 0.39 0.8227 0.9489 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C06 compound treatment 436664.0 132000.0 0.79 315265.0 -63100.0 -0.36 0.303 0.3504 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C07 compound treatment 276427.0 -28000.0 -0.17 476191.0 97900.0 0.56 0.2758 0.4747 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C08 compound treatment 270502.0 -33900.0 -0.2 458522.0 80200.0 0.46 0.1798 0.3605 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C09 compound treatment 371084.0 66700.0 0.4 223646.0 -155000.0 -0.88 -0.3414 -0.3538 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C10 compound treatment 358140.0 53700.0 0.32 439268.0 61000.0 0.35 0.4712 0.9992 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C11 mock treatment 197932.0 -106000.0 -0.63 234194.0 -144000.0 -0.82 -1.0276 -0.9919 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C12 mock treatment 273714.0 -30700.0 -0.18 232993.0 -145000.0 -0.83 -0.7135 -0.8431 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C13 compound treatment 275932.0 -28500.0 -0.17 444953.0 66600.0 0.38 0.1481 0.3568 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C14 compound treatment 377121.0 72700.0 0.43 428570.0 50300.0 0.29 0.5081 0.9797 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C15 mock treatment 75960.0 -228000.0 -1.36 158495.0 -220000.0 -1.25 -1.8453 -0.9991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C16 mock treatment 138848.0 -166000.0 -0.99 161087.0 -217000.0 -1.24 -1.5702 -0.9937 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C17 compound treatment 411795.0 107000.0 0.64 412505.0 34200.0 0.19 0.5894 0.8823 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C18 compound treatment 388761.0 84300.0 0.5 473698.0 95400.0 0.54 0.7385 0.9993 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C19 compound treatment 429816.0 125000.0 0.75 429334.0 51000.0 0.29 0.7329 0.9153 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C20 compound treatment 417833.0 113000.0 0.68 450017.0 71700.0 0.41 0.7656 0.9709 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C21 compound treatment 246485.0 -57900.0 -0.34 416223.0 37900.0 0.22 -0.0913 -0.2246 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C22 compound treatment 273518.0 -30900.0 -0.18 487951.0 110000.0 0.62 0.3109 0.4782 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C23 compound treatment 335760.0 31300.0 0.19 427495.0 49200.0 0.28 0.3297 0.9806 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 C24 compound treatment 473334.0 169000.0 1.01 509711.0 131000.0 0.75 1.2392 0.9893 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D01 compound treatment 476995.0 173000.0 1.03 206707.0 -172000.0 -0.98 0.0362 0.0256 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D02 compound treatment 431298.0 127000.0 0.76 518324.0 140000.0 0.8 1.097 0.9997 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D03 compound treatment 427214.0 123000.0 0.73 245900.0 -132000.0 -0.75 -0.0157 -0.0149 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D04 compound treatment 443309.0 139000.0 0.83 492031.0 114000.0 0.65 1.0418 0.9926 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D05 compound treatment 451610.0 147000.0 0.88 512897.0 135000.0 0.77 1.1606 0.9977 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D06 compound treatment 438332.0 134000.0 0.8 450160.0 71800.0 0.41 0.8525 0.9518 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D07 compound treatment 427252.0 123000.0 0.73 308723.0 -69600.0 -0.4 0.2371 0.2852 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D08 compound treatment 432443.0 128000.0 0.76 293856.0 -84500.0 -0.48 0.1992 0.2211 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D09 compound treatment 434734.0 130000.0 0.78 492625.0 114000.0 0.65 1.0081 0.9961 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D10 compound treatment 450874.0 146000.0 0.87 440756.0 62400.0 0.36 0.8674 0.9216 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D11 mock treatment 425634.0 121000.0 0.72 471764.0 93400.0 0.53 0.8859 0.9887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D12 mock treatment 425178.0 121000.0 0.72 442833.0 64500.0 0.37 0.7677 0.9513 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D13 compound treatment 301878.0 -2530.0 -0.02 442055.0 63700.0 0.36 0.2456 0.6771 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D14 compound treatment 438978.0 135000.0 0.8 465326.0 87000.0 0.49 0.9162 0.9732 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D15 mock treatment 442328.0 138000.0 0.82 461690.0 83400.0 0.47 0.9157 0.966 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D16 mock treatment 336535.0 32100.0 0.19 425141.0 46800.0 0.27 0.3235 0.9868 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D17 compound treatment 257341.0 -47100.0 -0.28 333388.0 -44900.0 -0.26 -0.3787 -0.9989 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D18 compound treatment 455421.0 151000.0 0.9 471311.0 93000.0 0.53 1.0094 0.968 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D19 compound treatment 325416.0 21000.0 0.13 320902.0 -57400.0 -0.33 -0.1425 -0.4075 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D20 compound treatment 483231.0 179000.0 1.06 430686.0 52400.0 0.3 0.9631 0.8715 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D21 compound treatment 225639.0 -78800.0 -0.47 229823.0 -148000.0 -0.84 -0.9286 -0.9614 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D22 compound treatment 296640.0 -7770.0 -0.05 215364.0 -163000.0 -0.93 -0.688 -0.7415 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D23 compound treatment 188304.0 -116000.0 -0.69 190025.0 -188000.0 -1.07 -1.2458 -0.9775 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 D24 compound treatment 530575.0 226000.0 1.35 251783.0 -127000.0 -0.72 0.443 0.2902 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E01 mock treatment 229769.0 -74600.0 -0.44 238726.0 -140000.0 -0.79 -0.8754 -0.9624 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E02 mock treatment 232361.0 -72100.0 -0.43 256110.0 -122000.0 -0.69 -0.7946 -0.9731 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E03 compound treatment 176864.0 -128000.0 -0.76 466760.0 88400.0 0.5 -0.1811 -0.1989 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E04 compound treatment 274055.0 -30400.0 -0.18 510098.0 132000.0 0.75 0.4022 0.5217 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E05 compound treatment 427186.0 123000.0 0.73 485760.0 107000.0 0.61 0.9487 0.996 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E06 compound treatment 430411.0 126000.0 0.75 475836.0 97500.0 0.55 0.9224 0.989 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E07 compound treatment 280244.0 -24200.0 -0.14 522911.0 145000.0 0.82 0.4797 0.5747 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E08 compound treatment 413116.0 109000.0 0.65 486723.0 108000.0 0.62 0.8934 0.9997 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E09 mock treatment 329987.0 25600.0 0.15 198194.0 -180000.0 -1.02 -0.6167 -0.5955 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E10 mock treatment 210574.0 -93800.0 -0.56 253408.0 -125000.0 -0.71 -0.8972 -0.9929 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E11 compound treatment 334357.0 29900.0 0.18 482003.0 104000.0 0.59 0.543 0.8814 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E12 compound treatment 378315.0 73900.0 0.44 204423.0 -174000.0 -0.99 -0.3882 -0.3587 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E13 compound treatment 399929.0 95500.0 0.57 423343.0 45000.0 0.26 0.583 0.9351 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E14 compound treatment 447281.0 143000.0 0.85 276128.0 -102000.0 -0.58 0.1903 0.1848 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E15 compound treatment 240538.0 -63900.0 -0.38 395261.0 16900.0 0.1 -0.2007 -0.5117 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E16 compound treatment 324477.0 20100.0 0.12 380268.0 1950.0 0.01 0.0923 0.7695 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E17 mock treatment 129319.0 -175000.0 -1.04 79942.0 -298000.0 -1.7 -1.9366 -0.9726 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E18 mock treatment 164241.0 -140000.0 -0.83 163348.0 -215000.0 -1.22 -1.4543 -0.9826 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E19 compound treatment 398894.0 94500.0 0.56 498218.0 120000.0 0.68 0.8798 0.9954 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E20 compound treatment 284840.0 -19600.0 -0.12 218509.0 -160000.0 -0.91 -0.725 -0.7913 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E21 compound treatment 465233.0 161000.0 0.96 468348.0 90000.0 0.51 1.0388 0.957 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E22 compound treatment 391042.0 86600.0 0.52 372126.0 -6190.0 -0.04 0.3397 0.6573 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E23 compound treatment 369578.0 65200.0 0.39 207330.0 -171000.0 -0.97 -0.4133 -0.3948 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 E24 compound treatment 501157.0 197000.0 1.17 399729.0 21400.0 0.12 0.9141 0.7765 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F01 mock treatment 486925.0 183000.0 1.09 547966.0 170000.0 0.96 1.4503 0.9983 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F02 mock treatment 388949.0 84500.0 0.5 498414.0 120000.0 0.68 0.8387 0.9887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F03 compound treatment 169728.0 -135000.0 -0.8 558808.0 180000.0 1.03 0.159 0.1221 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F04 compound treatment 499617.0 195000.0 1.16 428747.0 50400.0 0.29 1.0243 0.856 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F05 compound treatment 498497.0 194000.0 1.16 432746.0 54400.0 0.31 1.0356 0.866 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F06 compound treatment 459034.0 155000.0 0.92 447441.0 69100.0 0.39 0.9287 0.928 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F07 compound treatment 476150.0 172000.0 1.02 483512.0 105000.0 0.6 1.1457 0.9674 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F08 compound treatment 489397.0 185000.0 1.1 425004.0 46700.0 0.27 0.9662 0.8532 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F09 mock treatment 450702.0 146000.0 0.87 462151.0 83800.0 0.48 0.9527 0.9598 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F10 mock treatment 237289.0 -67100.0 -0.4 444216.0 65900.0 0.37 -0.0175 -0.0319 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F11 compound treatment 438688.0 134000.0 0.8 540269.0 162000.0 0.92 1.2163 0.9975 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F12 compound treatment 503040.0 199000.0 1.18 425878.0 47600.0 0.27 1.0271 0.847 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F13 compound treatment 190550.0 -114000.0 -0.68 461608.0 83300.0 0.47 -0.1442 -0.1744 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F14 compound treatment 435670.0 131000.0 0.78 297130.0 -81200.0 -0.46 0.2259 0.249 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F15 compound treatment 457872.0 153000.0 0.91 477323.0 99000.0 0.56 1.0439 0.973 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F16 compound treatment 423230.0 119000.0 0.71 421998.0 43700.0 0.25 0.6757 0.9015 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F17 mock treatment 428712.0 124000.0 0.74 497913.0 120000.0 0.68 1.004 0.9991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F18 mock treatment 473047.0 169000.0 1.0 460833.0 82500.0 0.47 1.0415 0.94 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F19 compound treatment 457952.0 154000.0 0.91 488672.0 110000.0 0.63 1.0899 0.9832 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F20 compound treatment 404105.0 99700.0 0.59 434774.0 56500.0 0.32 0.6466 0.9584 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F21 compound treatment 581020.0 277000.0 1.65 481703.0 103000.0 0.59 1.5798 0.9037 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F22 compound treatment 388177.0 83800.0 0.5 413395.0 35100.0 0.2 0.4936 0.9192 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F23 compound treatment 562092.0 258000.0 1.53 314172.0 -64100.0 -0.36 0.8265 0.5243 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 F24 compound treatment 461419.0 157000.0 0.93 444148.0 65800.0 0.37 0.9255 0.9194 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G01 compound treatment 475547.0 171000.0 1.02 490874.0 113000.0 0.64 1.1728 0.9749 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G02 compound treatment 356271.0 51900.0 0.31 507202.0 129000.0 0.73 0.7365 0.9261 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G03 mock treatment 205471.0 -98900.0 -0.59 211749.0 -167000.0 -0.95 -1.0862 -0.9738 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G04 mock treatment 154622.0 -150000.0 -0.89 287115.0 -91200.0 -0.52 -0.9971 -0.9668 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G05 compound treatment 461068.0 157000.0 0.93 499899.0 122000.0 0.69 1.1482 0.9892 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G06 compound treatment 217965.0 -86400.0 -0.51 444246.0 65900.0 0.37 -0.0987 -0.155 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G07 compound treatment 273688.0 -30700.0 -0.18 304859.0 -73500.0 -0.42 -0.4247 -0.9313 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G08 compound treatment 515825.0 211000.0 1.26 423601.0 45300.0 0.26 1.0718 0.8345 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G09 compound treatment 271003.0 -33400.0 -0.2 430690.0 52400.0 0.3 0.07 0.1955 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G10 compound treatment 404970.0 101000.0 0.6 493078.0 115000.0 0.65 0.8847 0.9991 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G11 compound treatment 417822.0 113000.0 0.67 418382.0 40100.0 0.23 0.6384 0.8961 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G12 compound treatment 228600.0 -75800.0 -0.45 519376.0 141000.0 0.8 0.2482 0.2697 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G13 compound treatment 468125.0 164000.0 0.97 476153.0 97800.0 0.56 1.0824 0.9647 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G14 compound treatment 476159.0 172000.0 1.02 449767.0 71500.0 0.41 1.0101 0.9183 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G15 compound treatment 353482.0 49100.0 0.29 487587.0 109000.0 0.62 0.6459 0.9407 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G16 compound treatment 212842.0 -91600.0 -0.54 428902.0 50600.0 0.29 -0.1819 -0.2952 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G17 compound treatment 174418.0 -130000.0 -0.77 391069.0 12800.0 0.07 -0.4958 -0.638 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G18 compound treatment 276931.0 -27500.0 -0.16 467102.0 88800.0 0.5 0.2414 0.4548 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G19 mock treatment 131756.0 -173000.0 -1.03 69952.0 -308000.0 -1.75 -1.9666 -0.9676 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G20 mock treatment 217794.0 -86600.0 -0.52 41673.0 -337000.0 -1.91 -1.7182 -0.8666 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G21 compound treatment 461376.0 157000.0 0.93 420108.0 41800.0 0.24 0.8286 0.8596 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G22 compound treatment 322505.0 18100.0 0.11 469083.0 90800.0 0.52 0.4411 0.8366 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G23 compound treatment 472894.0 168000.0 1.0 488946.0 111000.0 0.63 1.1539 0.9748 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 G24 compound treatment 227817.0 -76600.0 -0.46 517969.0 140000.0 0.79 0.2392 0.2613 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H01 compound treatment 298762.0 -5650.0 -0.03 573043.0 195000.0 1.11 0.7593 0.6853 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H02 compound treatment 449612.0 145000.0 0.86 482810.0 104000.0 0.59 1.0312 0.9833 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H03 mock treatment 480819.0 176000.0 1.05 487641.0 109000.0 0.62 1.182 0.9687 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H04 mock treatment 171448.0 -133000.0 -0.79 459921.0 81600.0 0.46 -0.2314 -0.2522 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H05 compound treatment 510747.0 206000.0 1.23 473615.0 95300.0 0.54 1.2515 0.9324 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H06 compound treatment 478418.0 174000.0 1.04 468449.0 90100.0 0.51 1.0947 0.9474 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H07 compound treatment 280811.0 -23600.0 -0.14 250330.0 -128000.0 -0.73 -0.614 -0.8283 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H08 compound treatment 461090.0 157000.0 0.93 184479.0 -194000.0 -1.1 -0.1201 -0.0832 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H09 compound treatment 423941.0 120000.0 0.71 225281.0 -153000.0 -0.87 -0.1124 -0.1 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H10 compound treatment 216812.0 -87600.0 -0.52 477363.0 99000.0 0.56 0.0296 0.0386 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H11 compound treatment 479405.0 175000.0 1.04 490047.0 112000.0 0.64 1.1857 0.9719 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H12 compound treatment 253270.0 -51100.0 -0.3 429293.0 51000.0 0.29 -0.0102 -0.0243 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H13 compound treatment 283418.0 -21000.0 -0.12 497672.0 119000.0 0.68 0.3916 0.5674 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H14 compound treatment 297358.0 -7050.0 -0.04 477419.0 99100.0 0.56 0.3688 0.6526 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H15 compound treatment 389276.0 84900.0 0.51 324365.0 -54000.0 -0.31 0.1402 0.2372 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H16 compound treatment 214301.0 -90100.0 -0.54 504864.0 127000.0 0.72 0.1297 0.1445 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H17 compound treatment 406094.0 102000.0 0.61 469361.0 91000.0 0.52 0.794 0.997 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H18 compound treatment 437526.0 133000.0 0.79 382283.0 3970.0 0.02 0.5761 0.727 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H19 mock treatment 460599.0 156000.0 0.93 480110.0 102000.0 0.58 1.0666 0.974 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H20 mock treatment 451200.0 147000.0 0.87 507576.0 129000.0 0.74 1.1375 0.9963 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H21 compound treatment 464835.0 160000.0 0.95 465795.0 87500.0 0.5 1.0269 0.9538 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H22 compound treatment 189965.0 -114000.0 -0.68 223616.0 -155000.0 -0.88 -1.1037 -0.992 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H23 compound treatment 517736.0 213000.0 1.27 563309.0 185000.0 1.05 1.6416 0.9956 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 H24 compound treatment 274453.0 -30000.0 -0.18 487993.0 110000.0 0.62 0.315 0.4855 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I01 compound treatment 479946.0 176000.0 1.04 472871.0 94600.0 0.54 1.1189 0.9523 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I02 compound treatment 422524.0 118000.0 0.7 426917.0 48600.0 0.28 0.6925 0.9168 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I03 compound treatment 465806.0 161000.0 0.96 476667.0 98400.0 0.56 1.0747 0.9669 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I04 compound treatment 490497.0 186000.0 1.11 433146.0 54800.0 0.31 1.0036 0.8723 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I05 mock treatment 302047.0 -2360.0 -0.01 310131.0 -68200.0 -0.39 -0.2841 -0.7323 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I06 mock treatment 295154.0 -9260.0 -0.06 287972.0 -90300.0 -0.51 -0.4022 -0.7785 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I07 compound treatment 350171.0 45800.0 0.27 501282.0 123000.0 0.7 0.687 0.9155 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I08 compound treatment 265683.0 -38700.0 -0.23 468890.0 90600.0 0.52 0.2012 0.3566 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I09 compound treatment 287047.0 -17400.0 -0.1 619483.0 241000.0 1.37 0.8967 0.652 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I10 compound treatment 348425.0 44000.0 0.26 512326.0 134000.0 0.76 0.7241 0.8986 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I11 compound treatment 178164.0 -126000.0 -0.75 250013.0 -128000.0 -0.73 -1.0472 -0.9999 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I12 compound treatment 309440.0 5030.0 0.03 415655.0 37300.0 0.21 0.1713 0.7989 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I13 compound treatment 232795.0 -71600.0 -0.43 465092.0 86800.0 0.49 0.0476 0.0729 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I14 compound treatment 476494.0 172000.0 1.02 270740.0 -108000.0 -0.61 0.2916 0.2444 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I15 compound treatment 358470.0 54100.0 0.32 163723.0 -215000.0 -1.22 -0.6354 -0.5035 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I16 compound treatment 340759.0 36300.0 0.22 476210.0 97900.0 0.56 0.5466 0.9152 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I17 compound treatment 300755.0 -3660.0 -0.02 356718.0 -21600.0 -0.12 -0.1022 -0.8196 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I18 compound treatment 404499.0 100000.0 0.6 498526.0 120000.0 0.68 0.9046 0.9976 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I19 compound treatment 447718.0 143000.0 0.85 244610.0 -134000.0 -0.76 0.0654 0.0573 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I20 compound treatment 464163.0 160000.0 0.95 446536.0 68200.0 0.39 0.9466 0.9218 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I21 mock treatment 152332.0 -152000.0 -0.91 187628.0 -191000.0 -1.08 -1.4068 -0.996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I22 mock treatment 169767.0 -135000.0 -0.8 136916.0 -241000.0 -1.37 -1.5373 -0.9671 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I23 compound treatment 131227.0 -173000.0 -1.03 364909.0 -13400.0 -0.08 -0.7827 -0.7573 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 I24 compound treatment 490640.0 186000.0 1.11 532708.0 154000.0 0.88 1.4045 0.9933 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J01 compound treatment 195630.0 -109000.0 -0.65 561943.0 184000.0 1.04 0.2806 0.2284 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J02 compound treatment 208023.0 -96400.0 -0.57 460232.0 81900.0 0.47 -0.0762 -0.1032 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J03 compound treatment 68788.0 -236000.0 -1.4 501558.0 123000.0 0.7 -0.496 -0.3164 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J04 compound treatment 153567.0 -151000.0 -0.9 490297.0 112000.0 0.64 -0.1845 -0.1676 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J05 mock treatment 269963.0 -34400.0 -0.21 467274.0 89000.0 0.51 0.2127 0.3898 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J06 mock treatment 232177.0 -72200.0 -0.43 495672.0 117000.0 0.67 0.1679 0.2115 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J07 compound treatment 501701.0 197000.0 1.17 534262.0 156000.0 0.89 1.4573 0.9904 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J08 compound treatment 304732.0 321.0 0.0 532043.0 154000.0 0.87 0.6195 0.7087 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J09 compound treatment 536809.0 232000.0 1.38 529475.0 151000.0 0.86 1.5858 0.9738 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J10 compound treatment 421761.0 117000.0 0.7 582684.0 204000.0 1.16 1.3156 0.9703 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J11 compound treatment 484085.0 180000.0 1.07 463228.0 84900.0 0.48 1.0976 0.9355 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J12 compound treatment 556702.0 252000.0 1.5 511069.0 133000.0 0.75 1.5955 0.9494 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J13 compound treatment 213906.0 -90500.0 -0.54 492799.0 114000.0 0.65 0.0795 0.0941 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J14 compound treatment 292394.0 -12000.0 -0.07 485205.0 107000.0 0.61 0.3792 0.6196 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J15 compound treatment 277233.0 -27200.0 -0.16 495092.0 117000.0 0.66 0.3552 0.5197 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J16 compound treatment 336928.0 32500.0 0.19 364471.0 -13800.0 -0.08 0.0812 0.3885 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J17 compound treatment 183027.0 -121000.0 -0.72 391210.0 12900.0 0.07 -0.459 -0.6321 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J18 compound treatment 412347.0 108000.0 0.64 320193.0 -58100.0 -0.33 0.2205 0.3052 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J19 compound treatment 548713.0 244000.0 1.45 498442.0 120000.0 0.68 1.5111 0.9407 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J20 compound treatment 202549.0 -102000.0 -0.61 237163.0 -141000.0 -0.8 -0.9963 -0.9904 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J21 mock treatment 453004.0 149000.0 0.88 518887.0 141000.0 0.8 1.1906 0.9987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J22 mock treatment 257539.0 -46900.0 -0.28 303149.0 -75200.0 -0.43 -0.4995 -0.9786 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J23 compound treatment 570560.0 266000.0 1.58 557026.0 179000.0 1.02 1.8387 0.977 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 J24 compound treatment 537086.0 233000.0 1.38 510962.0 133000.0 0.75 1.5126 0.9592 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K01 compound treatment 506478.0 202000.0 1.2 570311.0 192000.0 1.09 1.6224 0.9988 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K02 compound treatment 467636.0 163000.0 0.97 660491.0 282000.0 1.6 1.8216 0.9711 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K03 compound treatment 474322.0 170000.0 1.01 492018.0 114000.0 0.65 1.1722 0.9767 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K04 compound treatment 523676.0 219000.0 1.3 311468.0 -66800.0 -0.38 0.6539 0.4811 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K05 compound treatment 563049.0 259000.0 1.54 366716.0 -11600.0 -0.07 1.0418 0.6762 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K06 compound treatment 523000.0 219000.0 1.3 550678.0 172000.0 0.98 1.613 0.9903 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K07 mock treatment 244252.0 -60200.0 -0.36 300771.0 -77500.0 -0.44 -0.565 -0.9947 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K08 mock treatment 300664.0 -3750.0 -0.02 329590.0 -48700.0 -0.28 -0.2117 -0.7616 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K09 compound treatment 513046.0 209000.0 1.24 447078.0 68800.0 0.39 1.1545 0.8869 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K10 compound treatment 497375.0 193000.0 1.15 577515.0 199000.0 1.13 1.6131 1.0 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K11 compound treatment 495097.0 191000.0 1.13 314455.0 -63900.0 -0.36 0.5457 0.458 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K12 compound treatment 183453.0 -121000.0 -0.72 376779.0 -1540.0 -0.01 -0.5152 -0.7156 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K13 compound treatment 554621.0 250000.0 1.49 496077.0 118000.0 0.67 1.5265 0.9349 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K14 compound treatment 421979.0 118000.0 0.7 344755.0 -33600.0 -0.19 0.3598 0.4961 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K15 mock treatment 217343.0 -87100.0 -0.52 243811.0 -135000.0 -0.76 -0.9073 -0.982 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K16 mock treatment 209205.0 -95200.0 -0.57 227717.0 -151000.0 -0.86 -1.0062 -0.9799 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K17 compound treatment 527360.0 223000.0 1.33 533985.0 156000.0 0.89 1.5642 0.9807 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K18 compound treatment 421849.0 117000.0 0.7 492779.0 114000.0 0.65 0.9545 0.9994 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K19 compound treatment 486781.0 182000.0 1.09 530568.0 152000.0 0.87 1.3797 0.9937 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K20 compound treatment 543790.0 239000.0 1.42 440487.0 62200.0 0.35 1.2574 0.8566 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K21 compound treatment 437828.0 133000.0 0.79 518123.0 140000.0 0.8 1.1236 1.0 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K22 compound treatment 383997.0 79600.0 0.47 543105.0 165000.0 0.94 0.9976 0.95 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K23 mock treatment 182406.0 -122000.0 -0.73 248406.0 -130000.0 -0.74 -1.0358 -1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 K24 mock treatment 107644.0 -197000.0 -1.17 213531.0 -165000.0 -0.94 -1.4907 -0.9939 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L01 compound treatment 340608.0 36200.0 0.22 489473.0 111000.0 0.63 0.5993 0.8974 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L02 compound treatment 483035.0 179000.0 1.06 491736.0 113000.0 0.64 1.2078 0.9713 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L03 compound treatment 522216.0 218000.0 1.3 497425.0 119000.0 0.68 1.3955 0.9542 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L04 compound treatment 495550.0 191000.0 1.14 532840.0 155000.0 0.88 1.4257 0.9919 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L05 compound treatment 562999.0 259000.0 1.54 485386.0 107000.0 0.61 1.5188 0.9177 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L06 compound treatment 514805.0 210000.0 1.25 532484.0 154000.0 0.88 1.5053 0.9848 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L07 mock treatment 186602.0 -118000.0 -0.7 328137.0 -50200.0 -0.29 -0.6975 -0.9215 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L08 mock treatment 298080.0 -6330.0 -0.04 554725.0 176000.0 1.0 0.6827 0.6801 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L09 compound treatment 518798.0 214000.0 1.28 332750.0 -45600.0 -0.26 0.719 0.5522 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L10 compound treatment 538538.0 234000.0 1.39 530646.0 152000.0 0.87 1.5978 0.9739 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L11 compound treatment 557146.0 253000.0 1.5 384319.0 6000.0 0.03 1.0877 0.723 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L12 compound treatment 490596.0 186000.0 1.11 515805.0 137000.0 0.78 1.3364 0.9854 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L13 compound treatment 562296.0 258000.0 1.53 527332.0 149000.0 0.85 1.6845 0.9608 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L14 compound treatment 647925.0 344000.0 2.04 536417.0 158000.0 0.9 2.0814 0.9319 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L15 mock treatment 505297.0 201000.0 1.2 505487.0 127000.0 0.72 1.3568 0.971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L16 mock treatment 255241.0 -49200.0 -0.29 541247.0 163000.0 0.93 0.4482 0.4613 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L17 compound treatment 321966.0 17600.0 0.1 544606.0 166000.0 0.95 0.7426 0.7805 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L18 compound treatment 435689.0 131000.0 0.78 445007.0 66700.0 0.38 0.8206 0.9449 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L19 compound treatment 550476.0 246000.0 1.46 507686.0 129000.0 0.74 1.5557 0.9493 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L20 compound treatment 191182.0 -113000.0 -0.67 203463.0 -175000.0 -0.99 -1.1796 -0.982 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L21 compound treatment 509663.0 205000.0 1.22 514746.0 136000.0 0.78 1.4124 0.976 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L22 compound treatment 254738.0 -49700.0 -0.3 409821.0 31500.0 0.18 -0.0823 -0.2382 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L23 mock treatment 501539.0 197000.0 1.17 526182.0 148000.0 0.84 1.4242 0.9867 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 L24 mock treatment 398050.0 93600.0 0.56 435975.0 57700.0 0.33 0.6259 0.968 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M01 compound treatment 515713.0 211000.0 1.26 506106.0 128000.0 0.73 1.4031 0.966 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M02 compound treatment 244740.0 -59700.0 -0.36 379803.0 1490.0 0.01 -0.2451 -0.6901 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M03 compound treatment 526996.0 223000.0 1.32 563293.0 185000.0 1.05 1.6805 0.9935 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M04 compound treatment 288518.0 -15900.0 -0.09 521351.0 143000.0 0.81 0.5083 0.6207 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M05 compound treatment 273536.0 -30900.0 -0.18 556136.0 178000.0 1.01 0.5851 0.5693 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M06 compound treatment 290743.0 -13700.0 -0.08 600208.0 222000.0 1.26 0.8347 0.6602 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M07 compound treatment 314031.0 9620.0 0.06 557753.0 179000.0 1.02 0.762 0.7456 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M08 compound treatment 298799.0 -5610.0 -0.03 544773.0 166000.0 0.95 0.6457 0.6817 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M09 mock treatment 187063.0 -117000.0 -0.7 352691.0 -25600.0 -0.15 -0.5969 -0.8366 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M10 mock treatment 220321.0 -84100.0 -0.5 342387.0 -35900.0 -0.2 -0.4983 -0.9219 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M11 compound treatment 556252.0 252000.0 1.5 556983.0 179000.0 1.02 1.7783 0.9821 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M12 compound treatment 359017.0 54600.0 0.32 512830.0 135000.0 0.76 0.7707 0.9273 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M13 mock treatment 340063.0 35700.0 0.21 110950.0 -267000.0 -1.52 -0.9251 -0.6026 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M14 mock treatment 256656.0 -47800.0 -0.28 81748.0 -297000.0 -1.69 -1.3935 -0.8148 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M15 compound treatment 533920.0 230000.0 1.37 512752.0 134000.0 0.76 1.5064 0.9624 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M16 compound treatment 479807.0 175000.0 1.04 515213.0 137000.0 0.78 1.2886 0.9896 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M17 compound treatment 469676.0 165000.0 0.98 541276.0 163000.0 0.93 1.3508 0.9996 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M18 compound treatment 530518.0 226000.0 1.35 538423.0 160000.0 0.91 1.5953 0.9819 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M19 compound treatment 495834.0 191000.0 1.14 505261.0 127000.0 0.72 1.316 0.9758 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M20 compound treatment 497240.0 193000.0 1.15 502173.0 124000.0 0.7 1.3095 0.9725 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M21 compound treatment 448205.0 144000.0 0.86 500775.0 122000.0 0.7 1.0976 0.9948 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M22 compound treatment 407241.0 103000.0 0.61 484637.0 106000.0 0.6 0.8603 1.0 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M23 compound treatment 546318.0 242000.0 1.44 546586.0 168000.0 0.96 1.6947 0.9803 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 M24 compound treatment 564948.0 261000.0 1.55 614758.0 236000.0 1.34 2.0472 0.9975 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N01 compound treatment 484522.0 180000.0 1.07 488139.0 110000.0 0.62 1.1996 0.9669 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N02 compound treatment 437403.0 133000.0 0.79 488586.0 110000.0 0.63 1.0031 0.9934 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N03 compound treatment 533750.0 229000.0 1.36 537266.0 159000.0 0.9 1.6043 0.98 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N04 compound treatment 542983.0 239000.0 1.42 499842.0 122000.0 0.69 1.4927 0.9453 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N05 compound treatment 575783.0 271000.0 1.62 578626.0 200000.0 1.14 1.9475 0.9854 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N06 compound treatment 568284.0 264000.0 1.57 552806.0 174000.0 0.99 1.8121 0.9755 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N07 compound treatment 567082.0 263000.0 1.56 548528.0 170000.0 0.97 1.7898 0.9734 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N08 compound treatment 517239.0 213000.0 1.27 582805.0 204000.0 1.16 1.7179 0.9991 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N09 mock treatment 539532.0 235000.0 1.4 613565.0 235000.0 1.34 1.9354 0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N10 mock treatment 523987.0 220000.0 1.31 575418.0 197000.0 1.12 1.7166 0.9971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N11 compound treatment 334182.0 29800.0 0.18 531702.0 153000.0 0.87 0.7421 0.8337 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N12 compound treatment 510782.0 206000.0 1.23 540922.0 163000.0 0.92 1.5223 0.9902 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N13 mock treatment 244329.0 -60100.0 -0.36 535614.0 157000.0 0.89 0.3797 0.3941 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N14 mock treatment 495784.0 191000.0 1.14 509630.0 131000.0 0.75 1.3334 0.979 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N15 compound treatment 486381.0 182000.0 1.08 541834.0 164000.0 0.93 1.4233 0.9971 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N16 compound treatment 474007.0 170000.0 1.01 501577.0 123000.0 0.7 1.2094 0.9841 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N17 compound treatment 591416.0 287000.0 1.71 545153.0 167000.0 0.95 1.8787 0.9615 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N18 compound treatment 553905.0 249000.0 1.48 559516.0 181000.0 1.03 1.7786 0.9841 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N19 compound treatment 555805.0 251000.0 1.5 504587.0 126000.0 0.72 1.5657 0.9434 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N20 compound treatment 364017.0 59600.0 0.35 540478.0 162000.0 0.92 0.9029 0.9138 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N21 compound treatment 569501.0 265000.0 1.58 560495.0 182000.0 1.04 1.8481 0.9792 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N22 compound treatment 548417.0 244000.0 1.45 525520.0 147000.0 0.84 1.6188 0.9658 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N23 compound treatment 522087.0 218000.0 1.3 521453.0 143000.0 0.81 1.4916 0.9749 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 N24 compound treatment 581676.0 277000.0 1.65 477812.0 99500.0 0.57 1.5669 0.8982 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O01 compound treatment 601409.0 297000.0 1.77 557336.0 179000.0 1.02 1.9697 0.9657 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O02 compound treatment 430949.0 127000.0 0.75 486403.0 108000.0 0.61 0.9671 0.9949 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O03 compound treatment 546495.0 242000.0 1.44 574847.0 197000.0 1.12 1.809 0.9921 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O04 compound treatment 455345.0 151000.0 0.9 508552.0 130000.0 0.74 1.1589 0.9954 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O05 compound treatment 529981.0 226000.0 1.34 532482.0 154000.0 0.88 1.5692 0.9787 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O06 compound treatment 561687.0 257000.0 1.53 548006.0 170000.0 0.96 1.765 0.9752 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O07 compound treatment 534132.0 230000.0 1.37 584838.0 207000.0 1.17 1.7972 0.9971 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O08 compound treatment 322532.0 18100.0 0.11 446469.0 68200.0 0.39 0.3503 0.8708 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O09 compound treatment 538303.0 234000.0 1.39 568469.0 190000.0 1.08 1.7489 0.9922 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O10 compound treatment 506981.0 203000.0 1.21 516272.0 138000.0 0.78 1.4072 0.9783 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O11 mock treatment 386713.0 82300.0 0.49 438273.0 60000.0 0.34 0.5874 0.9843 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O12 mock treatment 247636.0 -56800.0 -0.34 362512.0 -15800.0 -0.09 -0.3025 -0.8651 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O13 compound treatment 510669.0 206000.0 1.23 618320.0 240000.0 1.36 1.8331 0.9986 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O14 compound treatment 538232.0 234000.0 1.39 612265.0 234000.0 1.33 1.9247 0.9997 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O15 compound treatment 517171.0 213000.0 1.27 621094.0 243000.0 1.38 1.8716 0.9991 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O16 compound treatment 506737.0 202000.0 1.2 599129.0 221000.0 1.26 1.7394 0.9998 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O17 compound treatment 481601.0 177000.0 1.05 189929.0 -188000.0 -1.07 -0.0119 -0.0079 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O18 compound treatment 504871.0 200000.0 1.19 609774.0 231000.0 1.32 1.7743 0.9988 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O19 compound treatment 511248.0 207000.0 1.23 498566.0 120000.0 0.68 1.354 0.9615 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O20 compound treatment 518100.0 214000.0 1.27 570698.0 192000.0 1.09 1.6729 0.9972 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O21 compound treatment 492000.0 188000.0 1.12 565863.0 188000.0 1.07 1.5436 0.9997 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O22 compound treatment 509476.0 205000.0 1.22 570661.0 192000.0 1.09 1.6364 0.9985 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O23 compound treatment 499321.0 195000.0 1.16 520136.0 142000.0 0.81 1.3905 0.9842 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 O24 compound treatment 453965.0 150000.0 0.89 562249.0 184000.0 1.05 1.369 0.9968 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P01 compound treatment 502012.0 198000.0 1.18 511027.0 133000.0 0.75 1.3652 0.977 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P02 compound treatment 554430.0 250000.0 1.49 441005.0 62700.0 0.36 1.3042 0.8524 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P03 compound treatment 551343.0 247000.0 1.47 567771.0 189000.0 1.08 1.801 0.9884 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P04 compound treatment 545277.0 241000.0 1.43 528585.0 150000.0 0.85 1.6179 0.9694 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P05 compound treatment 561200.0 257000.0 1.53 462032.0 83700.0 0.48 1.4173 0.8854 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P06 compound treatment 569331.0 265000.0 1.58 554528.0 176000.0 1.0 1.8234 0.9761 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P07 compound treatment 564473.0 260000.0 1.55 560270.0 182000.0 1.03 1.8261 0.9808 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P08 compound treatment 539522.0 235000.0 1.4 520068.0 142000.0 0.81 1.5594 0.9657 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P09 compound treatment 520200.0 216000.0 1.28 534877.0 157000.0 0.89 1.5377 0.984 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P10 compound treatment 319286.0 14900.0 0.09 621649.0 243000.0 1.38 1.0411 0.7508 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P11 mock treatment 531468.0 227000.0 1.35 527452.0 149000.0 0.85 1.5552 0.9748 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P12 mock treatment 526892.0 222000.0 1.32 498569.0 120000.0 0.68 1.4198 0.9527 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P13 compound treatment 558321.0 254000.0 1.51 590863.0 213000.0 1.21 1.9232 0.9939 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P14 compound treatment 572288.0 268000.0 1.59 558041.0 180000.0 1.02 1.85 0.9769 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P15 compound treatment 533655.0 229000.0 1.36 539427.0 161000.0 0.92 1.6126 0.9812 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P16 compound treatment 520793.0 216000.0 1.29 576973.0 199000.0 1.13 1.7094 0.9979 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P17 compound treatment 624282.0 320000.0 1.9 65562.0 -313000.0 -1.78 0.0885 0.034 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P18 compound treatment 503714.0 199000.0 1.19 562729.0 184000.0 1.05 1.5803 0.9981 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P19 compound treatment 477718.0 173000.0 1.03 580677.0 202000.0 1.15 1.5431 0.9985 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P20 compound treatment 570508.0 266000.0 1.58 137326.0 -241000.0 -1.37 0.1508 0.072 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P21 compound treatment 488015.0 184000.0 1.09 130429.0 -248000.0 -1.41 -0.2241 -0.1257 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P22 compound treatment 556517.0 252000.0 1.5 500756.0 122000.0 0.7 1.5533 0.9391 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P23 compound treatment 622412.0 318000.0 1.89 579089.0 201000.0 1.14 2.1456 0.9707 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2101 P24 compound treatment 499819.0 195000.0 1.16 573920.0 196000.0 1.11 1.6089 0.9998 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A01 compound treatment 140492.0 -254000.0 -1.51 195637.0 -199000.0 -1.13 -1.869 -0.9899 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A02 compound treatment 225980.0 -168000.0 -1.0 176877.0 -218000.0 -1.24 -1.5847 -0.9945 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A03 compound treatment 30728.0 -364000.0 -2.16 81073.0 -314000.0 -1.78 -2.7916 -0.9954 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A04 compound treatment 78135.0 -316000.0 -1.88 89070.0 -306000.0 -1.74 -2.5599 -0.9992 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A05 compound treatment 148537.0 -246000.0 -1.46 170023.0 -225000.0 -1.28 -1.9381 -0.9977 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A06 compound treatment 30001.0 -364000.0 -2.17 21880.0 -373000.0 -2.12 -3.0327 -0.9999 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A07 compound treatment 27128.0 -367000.0 -2.19 77000.0 -318000.0 -1.81 -2.8231 -0.9955 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A08 compound treatment 99000.0 -295000.0 -1.76 90649.0 -304000.0 -1.73 -2.4658 -1.0 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A09 compound treatment 60377.0 -334000.0 -1.99 80122.0 -315000.0 -1.79 -2.6706 -0.9986 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A10 compound treatment 99773.0 -295000.0 -1.75 120276.0 -274000.0 -1.56 -2.3434 -0.9983 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A11 compound treatment 245464.0 -149000.0 -0.89 256218.0 -138000.0 -0.79 -1.1836 -0.9983 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A12 compound treatment 272108.0 -122000.0 -0.73 245356.0 -149000.0 -0.85 -1.1152 -0.997 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A13 mock treatment 440028.0 45600.0 0.27 445612.0 50900.0 0.29 0.3967 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A14 mock treatment 471841.0 77500.0 0.46 444634.0 49900.0 0.28 0.5267 0.9729 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A15 compound treatment 64890.0 -330000.0 -1.96 69532.0 -325000.0 -1.85 -2.6942 -0.9996 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A16 compound treatment 21861.0 -373000.0 -2.22 73058.0 -322000.0 -1.83 -2.8611 -0.9954 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A17 compound treatment 74342.0 -320000.0 -1.9 52095.0 -343000.0 -1.95 -2.7246 -0.9999 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A18 compound treatment 76171.0 -318000.0 -1.89 71902.0 -323000.0 -1.84 -2.6372 -0.9999 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A19 compound treatment 68133.0 -326000.0 -1.94 65499.0 -329000.0 -1.87 -2.6968 -0.9998 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A20 compound treatment 73938.0 -320000.0 -1.91 73837.0 -321000.0 -1.82 -2.6388 -0.9998 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A21 compound treatment 173460.0 -221000.0 -1.31 449725.0 55000.0 0.31 -0.7085 -0.5242 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A22 compound treatment 48145.0 -346000.0 -2.06 18197.0 -377000.0 -2.14 -2.9711 -0.9998 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A23 compound treatment 117260.0 -277000.0 -1.65 191586.0 -203000.0 -1.16 -1.983 -0.9848 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 A24 compound treatment 176616.0 -218000.0 -1.3 172889.0 -222000.0 -1.26 -1.8084 -0.9999 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B01 compound treatment 291712.0 -103000.0 -0.61 314496.0 -80200.0 -0.46 -0.7547 -0.9896 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B02 compound treatment 168061.0 -226000.0 -1.35 190323.0 -204000.0 -1.16 -1.7743 -0.9973 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B03 compound treatment 174965.0 -219000.0 -1.31 191539.0 -203000.0 -1.16 -1.7404 -0.9981 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B04 compound treatment 351838.0 -42600.0 -0.25 376412.0 -18300.0 -0.1 -0.2527 -0.9228 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B05 compound treatment 72691.0 -322000.0 -1.91 47406.0 -347000.0 -1.98 -2.7504 -0.9999 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B06 compound treatment 150500.0 -244000.0 -1.45 260851.0 -134000.0 -0.76 -1.5646 -0.9546 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B07 compound treatment 159176.0 -235000.0 -1.4 163235.0 -231000.0 -1.32 -1.9207 -0.9995 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B08 compound treatment 76282.0 -318000.0 -1.89 94737.0 -300000.0 -1.71 -2.5449 -0.9986 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B09 compound treatment 227841.0 -167000.0 -0.99 122783.0 -272000.0 -1.55 -1.7944 -0.9769 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B10 compound treatment 141285.0 -253000.0 -1.51 34434.0 -360000.0 -2.05 -2.5139 -0.9886 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B11 compound treatment 71356.0 -323000.0 -1.92 19525.0 -375000.0 -2.13 -2.8681 -0.9986 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B12 compound treatment 223161.0 -171000.0 -1.02 188041.0 -207000.0 -1.18 -1.5516 -0.9975 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B13 mock treatment 423468.0 29100.0 0.17 182981.0 -212000.0 -1.2 -0.729 -0.5993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B14 mock treatment 477702.0 83300.0 0.5 464525.0 69800.0 0.4 0.6313 0.9939 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B15 compound treatment 288551.0 -106000.0 -0.63 257281.0 -137000.0 -0.78 -0.998 -0.9943 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B16 compound treatment 11093.0 -383000.0 -2.28 70245.0 -324000.0 -1.85 -2.9178 -0.9945 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B17 compound treatment 120985.0 -273000.0 -1.63 281933.0 -113000.0 -0.64 -1.6041 -0.9171 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B18 compound treatment 84074.0 -310000.0 -1.85 84864.0 -310000.0 -1.76 -2.5518 -0.9997 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B19 compound treatment 109383.0 -285000.0 -1.7 144887.0 -250000.0 -1.42 -2.204 -0.9961 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B20 compound treatment 63105.0 -331000.0 -1.97 66946.0 -328000.0 -1.86 -2.7121 -0.9996 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B21 compound treatment 104057.0 -290000.0 -1.73 81028.0 -314000.0 -1.78 -2.4832 -0.9999 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B22 compound treatment 60135.0 -334000.0 -1.99 142542.0 -252000.0 -1.43 -2.4207 -0.9871 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B23 compound treatment 420059.0 25700.0 0.15 311398.0 -83300.0 -0.47 -0.227 -0.456 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 B24 compound treatment 87734.0 -307000.0 -1.83 74223.0 -320000.0 -1.82 -2.5792 -1.0 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C01 compound treatment 262985.0 -131000.0 -0.78 529508.0 135000.0 0.77 -0.011 -0.01 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C02 compound treatment 124258.0 -270000.0 -1.61 120303.0 -274000.0 -1.56 -2.2402 -0.9999 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C03 compound treatment 73741.0 -321000.0 -1.91 67046.0 -328000.0 -1.86 -2.667 -0.9999 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C04 compound treatment 260845.0 -134000.0 -0.79 270903.0 -124000.0 -0.7 -1.0599 -0.9982 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C05 compound treatment 56119.0 -338000.0 -2.01 27020.0 -368000.0 -2.09 -2.9021 -0.9998 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C06 compound treatment 79862.0 -315000.0 -1.87 32042.0 -363000.0 -2.06 -2.782 -0.9988 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C07 compound treatment 74187.0 -320000.0 -1.91 59191.0 -336000.0 -1.91 -2.6967 -1.0 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C08 compound treatment 216311.0 -178000.0 -1.06 159557.0 -235000.0 -1.34 -1.695 -0.9934 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C09 compound treatment 66767.0 -328000.0 -1.95 69413.0 -325000.0 -1.85 -2.6868 -0.9997 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C10 compound treatment 96070.0 -298000.0 -1.78 107741.0 -287000.0 -1.63 -2.4094 -0.9991 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C11 mock treatment 416615.0 22200.0 0.13 433380.0 38700.0 0.22 0.249 0.9704 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C12 mock treatment 274940.0 -119000.0 -0.71 315144.0 -79600.0 -0.45 -0.8226 -0.9762 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C13 compound treatment 88984.0 -305000.0 -1.82 44133.0 -351000.0 -1.99 -2.695 -0.9989 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C14 compound treatment 76067.0 -318000.0 -1.89 47959.0 -347000.0 -1.97 -2.7339 -0.9998 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C15 mock treatment 253945.0 -140000.0 -0.84 361390.0 -33300.0 -0.19 -0.725 -0.8459 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C16 mock treatment 454462.0 60100.0 0.36 232762.0 -162000.0 -0.92 -0.3984 -0.4033 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C17 compound treatment 45665.0 -349000.0 -2.08 21679.0 -373000.0 -2.12 -2.9676 -0.9999 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C18 compound treatment 23873.0 -371000.0 -2.21 72805.0 -322000.0 -1.83 -2.8537 -0.9957 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C19 compound treatment 17991.0 -376000.0 -2.24 55193.0 -340000.0 -1.93 -2.9493 -0.9973 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C20 compound treatment 28007.0 -366000.0 -2.18 63857.0 -331000.0 -1.88 -2.8723 -0.9973 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C21 compound treatment 21568.0 -373000.0 -2.22 20382.0 -374000.0 -2.13 -3.0742 -0.9998 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C22 compound treatment 32393.0 -362000.0 -2.15 27242.0 -367000.0 -2.09 -3.001 -0.9999 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C23 compound treatment 240534.0 -154000.0 -0.92 249377.0 -145000.0 -0.83 -1.2319 -0.9987 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 C24 compound treatment 66206.0 -328000.0 -1.95 72382.0 -322000.0 -1.83 -2.6772 -0.9995 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D01 compound treatment 272470.0 -122000.0 -0.73 123454.0 -271000.0 -1.54 -1.6038 -0.9408 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D02 compound treatment 161486.0 -233000.0 -1.39 144991.0 -250000.0 -1.42 -1.9843 -0.9999 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D03 compound treatment 25391.0 -369000.0 -2.2 204662.0 -190000.0 -1.08 -2.3171 -0.9467 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D04 compound treatment 71796.0 -323000.0 -1.92 187429.0 -207000.0 -1.18 -2.1911 -0.9726 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D05 compound treatment 105765.0 -289000.0 -1.72 62788.0 -332000.0 -1.89 -2.5493 -0.9989 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D06 compound treatment 70335.0 -324000.0 -1.93 72251.0 -322000.0 -1.83 -2.6604 -0.9997 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D07 compound treatment 204273.0 -190000.0 -1.13 420820.0 26100.0 0.15 -0.6951 -0.6091 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D08 compound treatment 230896.0 -163000.0 -0.97 276965.0 -118000.0 -0.67 -1.1615 -0.9834 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D09 compound treatment 100718.0 -294000.0 -1.75 39834.0 -355000.0 -2.02 -2.6629 -0.9974 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D10 compound treatment 120754.0 -274000.0 -1.63 140765.0 -254000.0 -1.44 -2.1727 -0.9982 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D11 mock treatment 446544.0 52200.0 0.31 481097.0 86400.0 0.49 0.5668 0.9755 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D12 mock treatment 440252.0 45900.0 0.27 425317.0 30600.0 0.17 0.3161 0.9764 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D13 compound treatment 298460.0 -95900.0 -0.57 347521.0 -47200.0 -0.27 -0.5935 -0.9407 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D14 compound treatment 69594.0 -325000.0 -1.93 53147.0 -342000.0 -1.94 -2.7403 -1.0 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D15 mock treatment 538816.0 144000.0 0.86 456662.0 61900.0 0.35 0.8569 0.9224 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D16 mock treatment 388093.0 -6300.0 -0.04 411391.0 16700.0 0.09 0.0406 0.3978 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D17 compound treatment 56007.0 -338000.0 -2.01 88641.0 -306000.0 -1.74 -2.6548 -0.9974 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D18 compound treatment 434343.0 40000.0 0.24 484372.0 89700.0 0.51 0.5287 0.9397 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D19 compound treatment 65958.0 -328000.0 -1.95 64212.0 -331000.0 -1.88 -2.7111 -0.9998 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D20 compound treatment 63865.0 -331000.0 -1.97 63416.0 -331000.0 -1.88 -2.7231 -0.9998 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D21 compound treatment 258272.0 -136000.0 -0.81 271009.0 -124000.0 -0.7 -1.0703 -0.9975 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D22 compound treatment 357804.0 -36600.0 -0.22 330431.0 -64300.0 -0.37 -0.4125 -0.9694 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D23 compound treatment 276391.0 -118000.0 -0.7 291132.0 -104000.0 -0.59 -0.9131 -0.9962 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 D24 compound treatment 594160.0 200000.0 1.19 458001.0 63300.0 0.36 1.0952 0.8816 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E01 mock treatment 461589.0 67200.0 0.4 496382.0 102000.0 0.58 0.6916 0.9838 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E02 mock treatment 548993.0 155000.0 0.92 463095.0 68400.0 0.39 0.9256 0.9266 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E03 compound treatment 327665.0 -66700.0 -0.4 330338.0 -64400.0 -0.37 -0.5397 -0.9992 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E04 compound treatment 65995.0 -328000.0 -1.95 107186.0 -288000.0 -1.64 -2.5382 -0.9961 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E05 compound treatment 106382.0 -288000.0 -1.71 107912.0 -287000.0 -1.63 -2.3653 -0.9997 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E06 compound treatment 156788.0 -238000.0 -1.41 186862.0 -208000.0 -1.18 -1.8357 -0.996 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E07 compound treatment 66431.0 -328000.0 -1.95 72073.0 -323000.0 -1.83 -2.6775 -0.9995 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E08 compound treatment 111186.0 -283000.0 -1.69 77326.0 -317000.0 -1.8 -2.4681 -0.9994 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E09 mock treatment 601206.0 207000.0 1.23 419740.0 25000.0 0.14 0.971 0.7836 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E10 mock treatment 394192.0 -199.0 0.0 451336.0 56600.0 0.32 0.2269 0.7045 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E11 compound treatment 72756.0 -322000.0 -1.91 65859.0 -329000.0 -1.87 -2.6759 -0.9999 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E12 compound treatment 161759.0 -233000.0 -1.38 155369.0 -239000.0 -1.36 -1.9414 -1.0 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E13 compound treatment 58260.0 -336000.0 -2.0 61816.0 -333000.0 -1.89 -2.7532 -0.9996 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E14 compound treatment 213479.0 -181000.0 -1.08 216805.0 -178000.0 -1.01 -1.4767 -0.9995 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E15 compound treatment 70557.0 -324000.0 -1.93 60187.0 -335000.0 -1.9 -2.708 -1.0 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E16 compound treatment 365328.0 -29100.0 -0.17 378183.0 -16500.0 -0.09 -0.1888 -0.9589 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E17 mock treatment 287046.0 -107000.0 -0.64 384192.0 -10500.0 -0.06 -0.494 -0.77 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E18 mock treatment 323912.0 -70500.0 -0.42 376088.0 -18600.0 -0.11 -0.3715 -0.8587 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E19 compound treatment 57788.0 -337000.0 -2.0 63878.0 -331000.0 -1.88 -2.7469 -0.9995 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E20 compound treatment 275705.0 -119000.0 -0.71 158188.0 -237000.0 -1.35 -1.4506 -0.9548 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E21 compound treatment 95614.0 -299000.0 -1.78 74875.0 -320000.0 -1.82 -2.5435 -0.9999 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E22 compound treatment 59005.0 -335000.0 -2.0 56992.0 -338000.0 -1.92 -2.7694 -0.9998 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E23 compound treatment 171055.0 -223000.0 -1.33 165217.0 -229000.0 -1.31 -1.8627 -1.0 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 E24 compound treatment 67631.0 -327000.0 -1.94 64402.0 -330000.0 -1.88 -2.7033 -0.9998 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F01 mock treatment 511234.0 117000.0 0.7 253371.0 -141000.0 -0.8 -0.0766 -0.0721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F02 mock treatment 476752.0 82400.0 0.49 459357.0 64600.0 0.37 0.6065 0.9899 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F03 compound treatment 44458.0 -350000.0 -2.08 250935.0 -144000.0 -0.82 -2.0508 -0.9166 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F04 compound treatment 67556.0 -327000.0 -1.95 51386.0 -343000.0 -1.95 -2.756 -1.0 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F05 compound treatment 69424.0 -325000.0 -1.93 171300.0 -223000.0 -1.27 -2.2659 -0.9792 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F06 compound treatment 68593.0 -326000.0 -1.94 70058.0 -325000.0 -1.85 -2.6765 -0.9997 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F07 compound treatment 210384.0 -184000.0 -1.1 108385.0 -286000.0 -1.63 -1.9257 -0.9814 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F08 compound treatment 234484.0 -160000.0 -0.95 287115.0 -108000.0 -0.61 -1.1056 -0.9772 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F09 mock treatment 199989.0 -194000.0 -1.16 287535.0 -107000.0 -0.61 -1.2491 -0.9552 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F10 mock treatment 389580.0 -4810.0 -0.03 455544.0 60800.0 0.35 0.2244 0.6464 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F11 compound treatment 94990.0 -299000.0 -1.78 254661.0 -140000.0 -0.8 -1.8231 -0.9341 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F12 compound treatment 222333.0 -172000.0 -1.02 461163.0 66500.0 0.38 -0.4569 -0.4186 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F13 compound treatment 46150.0 -348000.0 -2.07 64038.0 -331000.0 -1.88 -2.7952 -0.9988 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F14 compound treatment 145105.0 -249000.0 -1.48 234473.0 -160000.0 -0.91 -1.6934 -0.9726 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F15 compound treatment 152450.0 -242000.0 -1.44 152264.0 -242000.0 -1.38 -1.9931 -0.9998 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F16 compound treatment 203900.0 -190000.0 -1.13 245072.0 -150000.0 -0.85 -1.4034 -0.99 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F17 mock treatment 348174.0 -46200.0 -0.28 406090.0 11400.0 0.06 -0.1487 -0.5264 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F18 mock treatment 285046.0 -109000.0 -0.65 465085.0 70400.0 0.4 -0.1772 -0.2319 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F19 compound treatment 114121.0 -280000.0 -1.67 22153.0 -373000.0 -2.12 -2.6776 -0.993 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F20 compound treatment 426504.0 32100.0 0.19 411962.0 17200.0 0.1 0.2045 0.952 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F21 compound treatment 253525.0 -141000.0 -0.84 262961.0 -132000.0 -0.75 -1.1226 -0.9984 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F22 compound treatment 36877.0 -358000.0 -2.13 62115.0 -333000.0 -1.89 -2.8419 -0.9983 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F23 compound treatment 256170.0 -138000.0 -0.82 307819.0 -86900.0 -0.49 -0.9311 -0.9703 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 F24 compound treatment 441052.0 46700.0 0.28 464786.0 70100.0 0.4 0.4781 0.9844 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G01 compound treatment 111049.0 -283000.0 -1.69 96857.0 -298000.0 -1.69 -2.3901 -1.0 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G02 compound treatment 288204.0 -106000.0 -0.63 171107.0 -224000.0 -1.27 -1.346 -0.9479 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G03 mock treatment 213919.0 -180000.0 -1.07 352373.0 -42300.0 -0.24 -0.9297 -0.8447 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G04 mock treatment 289082.0 -105000.0 -0.63 381456.0 -13300.0 -0.08 -0.4965 -0.7865 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G05 compound treatment 37843.0 -357000.0 -2.12 67273.0 -327000.0 -1.86 -2.8171 -0.9979 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G06 compound treatment 26266.0 -368000.0 -2.19 67072.0 -328000.0 -1.86 -2.8667 -0.9967 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G07 compound treatment 25589.0 -369000.0 -2.19 127628.0 -267000.0 -1.52 -2.626 -0.9838 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G08 compound treatment 126325.0 -268000.0 -1.6 145384.0 -249000.0 -1.42 -2.1307 -0.9983 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G09 compound treatment 16476.0 -378000.0 -2.25 68054.0 -327000.0 -1.86 -2.9039 -0.9955 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G10 compound treatment 64247.0 -330000.0 -1.96 85188.0 -310000.0 -1.76 -2.634 -0.9985 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G11 compound treatment 21678.0 -373000.0 -2.22 71429.0 -323000.0 -1.84 -2.8685 -0.9956 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G12 compound treatment 327193.0 -67200.0 -0.4 379916.0 -14800.0 -0.08 -0.3423 -0.8375 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G13 compound treatment 63441.0 -331000.0 -1.97 68617.0 -326000.0 -1.85 -2.704 -0.9995 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G14 compound treatment 67320.0 -327000.0 -1.95 70448.0 -324000.0 -1.84 -2.6803 -0.9996 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G15 compound treatment 65489.0 -329000.0 -1.96 58500.0 -336000.0 -1.91 -2.7361 -0.9999 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G16 compound treatment 109976.0 -284000.0 -1.69 106112.0 -289000.0 -1.64 -2.3574 -0.9999 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G17 compound treatment 60548.0 -334000.0 -1.99 26632.0 -368000.0 -2.09 -2.885 -0.9997 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G18 compound treatment 74905.0 -319000.0 -1.9 71515.0 -323000.0 -1.84 -2.6441 -0.9999 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G19 mock treatment 175860.0 -219000.0 -1.3 223595.0 -171000.0 -0.97 -1.6077 -0.9898 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G20 mock treatment 192939.0 -201000.0 -1.2 98419.0 -296000.0 -1.68 -2.0392 -0.9861 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G21 compound treatment 22962.0 -371000.0 -2.21 24117.0 -371000.0 -2.11 -3.0533 -0.9997 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G22 compound treatment 20430.0 -374000.0 -2.23 66337.0 -328000.0 -1.87 -2.8942 -0.9962 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G23 compound treatment 43459.0 -351000.0 -2.09 37991.0 -357000.0 -2.03 -2.9113 -0.9999 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 G24 compound treatment 68516.0 -326000.0 -1.94 90620.0 -304000.0 -1.73 -2.5942 -0.9984 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H01 compound treatment 334399.0 -60000.0 -0.36 331389.0 -63300.0 -0.36 -0.5071 -1.0 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H02 compound treatment 259795.0 -135000.0 -0.8 266771.0 -128000.0 -0.73 -1.0809 -0.9988 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H03 mock treatment 469283.0 74900.0 0.45 160802.0 -234000.0 -1.33 -0.6254 -0.4458 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H04 mock treatment 448453.0 54100.0 0.32 499871.0 105000.0 0.6 0.6504 0.9577 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H05 compound treatment 296954.0 -97400.0 -0.58 40186.0 -355000.0 -2.02 -1.8356 -0.875 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H06 compound treatment 76846.0 -318000.0 -1.89 73640.0 -321000.0 -1.83 -2.6274 -0.9999 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H07 compound treatment 204137.0 -190000.0 -1.13 129300.0 -265000.0 -1.51 -1.8679 -0.99 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H08 compound treatment 125583.0 -269000.0 -1.6 279682.0 -115000.0 -0.65 -1.5938 -0.9221 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H09 compound treatment 51733.0 -343000.0 -2.04 28226.0 -366000.0 -2.08 -2.9157 -0.9999 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H10 compound treatment 35641.0 -359000.0 -2.14 29855.0 -365000.0 -2.07 -2.9769 -0.9999 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H11 compound treatment 46996.0 -347000.0 -2.07 51576.0 -343000.0 -1.95 -2.8417 -0.9996 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H12 compound treatment 158247.0 -236000.0 -1.41 108394.0 -286000.0 -1.63 -2.1451 -0.9973 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H13 compound treatment 52029.0 -342000.0 -2.04 16796.0 -378000.0 -2.15 -2.9604 -0.9996 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H14 compound treatment 53429.0 -341000.0 -2.03 69324.0 -325000.0 -1.85 -2.7433 -0.9989 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H15 compound treatment 51983.0 -342000.0 -2.04 69997.0 -325000.0 -1.85 -2.7467 -0.9988 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H16 compound treatment 212600.0 -182000.0 -1.08 286584.0 -108000.0 -0.61 -1.1998 -0.9641 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H17 compound treatment 286030.0 -108000.0 -0.64 33416.0 -361000.0 -2.05 -1.9088 -0.8864 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H18 compound treatment 22243.0 -372000.0 -2.21 48590.0 -346000.0 -1.97 -2.9579 -0.9983 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H19 mock treatment 204667.0 -190000.0 -1.13 141217.0 -253000.0 -1.44 -1.8178 -0.9927 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H20 mock treatment 205731.0 -189000.0 -1.12 382521.0 -12200.0 -0.07 -0.843 -0.7493 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H21 compound treatment 42158.0 -352000.0 -2.1 64713.0 -330000.0 -1.88 -2.8093 -0.9985 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H22 compound treatment 35628.0 -359000.0 -2.14 80724.0 -314000.0 -1.79 -2.7724 -0.996 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H23 compound treatment 267374.0 -127000.0 -0.76 224338.0 -170000.0 -0.97 -1.2196 -0.9925 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 H24 compound treatment 457524.0 63100.0 0.38 553741.0 159000.0 0.9 0.9052 0.9243 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I01 compound treatment 103728.0 -291000.0 -1.73 240667.0 -154000.0 -0.88 -1.8426 -0.9503 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I02 compound treatment 116052.0 -278000.0 -1.66 247035.0 -148000.0 -0.84 -1.7652 -0.9504 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I03 compound treatment 315100.0 -79300.0 -0.47 341691.0 -53000.0 -0.3 -0.5469 -0.9766 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I04 compound treatment 71349.0 -323000.0 -1.92 79286.0 -315000.0 -1.79 -2.6278 -0.9994 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I05 mock treatment 239807.0 -155000.0 -0.92 343852.0 -50900.0 -0.29 -0.8551 -0.8866 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I06 mock treatment 314088.0 -80300.0 -0.48 324672.0 -70000.0 -0.4 -0.6196 -0.9959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I07 compound treatment 242469.0 -152000.0 -0.9 159928.0 -235000.0 -1.34 -1.5834 -0.982 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I08 compound treatment 220065.0 -174000.0 -1.04 249557.0 -145000.0 -0.83 -1.3173 -0.9936 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I09 compound treatment 278581.0 -116000.0 -0.69 516117.0 121000.0 0.69 8.0E-4 8.0E-4 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I10 compound treatment 57972.0 -336000.0 -2.0 79856.0 -315000.0 -1.79 -2.6818 -0.9984 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I11 compound treatment 62290.0 -332000.0 -1.98 71129.0 -324000.0 -1.84 -2.6988 -0.9994 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I12 compound treatment 122481.0 -272000.0 -1.62 154350.0 -240000.0 -1.37 -2.1108 -0.9965 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I13 compound treatment 65195.0 -329000.0 -1.96 70991.0 -324000.0 -1.84 -2.6871 -0.9995 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I14 compound treatment 115951.0 -278000.0 -1.66 110595.0 -284000.0 -1.62 -2.3142 -0.9999 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I15 compound treatment 100347.0 -294000.0 -1.75 101055.0 -294000.0 -1.67 -2.4183 -0.9997 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I16 compound treatment 68139.0 -326000.0 -1.94 68327.0 -326000.0 -1.86 -2.6854 -0.9997 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I17 compound treatment 79494.0 -315000.0 -1.87 48625.0 -346000.0 -1.97 -2.7168 -0.9997 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I18 compound treatment 230459.0 -164000.0 -0.98 101279.0 -293000.0 -1.67 -1.8698 -0.9673 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I19 compound treatment 213449.0 -181000.0 -1.08 255153.0 -140000.0 -0.79 -1.3226 -0.9887 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I20 compound treatment 61459.0 -333000.0 -1.98 49025.0 -346000.0 -1.97 -2.7911 -1.0 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I21 mock treatment 211754.0 -183000.0 -1.09 186453.0 -208000.0 -1.18 -1.606 -0.9991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I22 mock treatment 177169.0 -217000.0 -1.29 194620.0 -200000.0 -1.14 -1.7187 -0.998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I23 compound treatment 60948.0 -333000.0 -1.98 18178.0 -377000.0 -2.14 -2.9173 -0.9993 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 I24 compound treatment 69833.0 -325000.0 -1.93 67285.0 -327000.0 -1.86 -2.6825 -0.9998 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J01 compound treatment 210368.0 -184000.0 -1.1 269781.0 -125000.0 -0.71 -1.2768 -0.978 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J02 compound treatment 302338.0 -92100.0 -0.55 304510.0 -90200.0 -0.51 -0.7501 -0.9995 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J03 compound treatment 151569.0 -243000.0 -1.45 292700.0 -102000.0 -0.58 -1.4321 -0.9196 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J04 compound treatment 416241.0 21900.0 0.13 352107.0 -42600.0 -0.24 -0.0794 -0.2886 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J05 mock treatment 480615.0 86200.0 0.51 250908.0 -144000.0 -0.82 -0.2154 -0.2231 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J06 mock treatment 465454.0 71100.0 0.42 255962.0 -139000.0 -0.79 -0.2589 -0.2892 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J07 compound treatment 216686.0 -178000.0 -1.06 431545.0 36800.0 0.21 -0.5997 -0.5563 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J08 compound treatment 61279.0 -333000.0 -1.98 45828.0 -349000.0 -1.98 -2.8047 -1.0 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J09 compound treatment 157216.0 -237000.0 -1.41 119552.0 -275000.0 -1.56 -2.1046 -0.9987 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J10 compound treatment 248253.0 -146000.0 -0.87 255988.0 -139000.0 -0.79 -1.1728 -0.9988 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J11 compound treatment 144593.0 -250000.0 -1.49 71761.0 -323000.0 -1.84 -2.3499 -0.9945 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J12 compound treatment 70297.0 -324000.0 -1.93 41487.0 -353000.0 -2.01 -2.7843 -0.9998 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J13 compound treatment 364833.0 -29600.0 -0.18 319136.0 -75600.0 -0.43 -0.4283 -0.9223 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J14 compound treatment 284501.0 -110000.0 -0.65 240412.0 -154000.0 -0.88 -1.0829 -0.9895 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J15 compound treatment 71557.0 -323000.0 -1.92 47232.0 -347000.0 -1.98 -2.7558 -0.9999 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J16 compound treatment 46950.0 -347000.0 -2.07 241129.0 -154000.0 -0.87 -2.0797 -0.9265 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J17 compound treatment 38823.0 -356000.0 -2.12 62966.0 -332000.0 -1.89 -2.8303 -0.9984 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J18 compound treatment 71153.0 -323000.0 -1.92 67007.0 -328000.0 -1.86 -2.678 -0.9999 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J19 compound treatment 25644.0 -369000.0 -2.19 88844.0 -306000.0 -1.74 -2.7817 -0.9934 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J20 compound treatment 36179.0 -358000.0 -2.13 65685.0 -329000.0 -1.87 -2.8305 -0.9979 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J21 mock treatment 463478.0 69100.0 0.41 210587.0 -184000.0 -1.05 -0.4497 -0.3997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J22 mock treatment 468984.0 74600.0 0.44 447548.0 52800.0 0.3 0.5264 0.9819 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J23 compound treatment 67155.0 -327000.0 -1.95 65000.0 -330000.0 -1.87 -2.7029 -0.9998 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 J24 compound treatment 362106.0 -32300.0 -0.19 378717.0 -16000.0 -0.09 -0.2002 -0.9417 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K01 compound treatment 384214.0 -10200.0 -0.06 309479.0 -85200.0 -0.48 -0.3856 -0.7893 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K02 compound treatment 69790.0 -325000.0 -1.93 82361.0 -312000.0 -1.78 -2.622 -0.9991 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K03 compound treatment 285615.0 -109000.0 -0.65 355667.0 -39000.0 -0.22 -0.6148 -0.8983 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K04 compound treatment 269659.0 -125000.0 -0.74 370456.0 -24300.0 -0.14 -0.6224 -0.8244 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K05 compound treatment 302167.0 -92200.0 -0.55 499373.0 105000.0 0.6 0.0328 0.0405 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K06 compound treatment 77236.0 -317000.0 -1.89 75872.0 -319000.0 -1.81 -2.6168 -0.9998 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K07 mock treatment 380542.0 -13800.0 -0.08 427190.0 32500.0 0.18 0.0723 0.3576 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K08 mock treatment 402969.0 8580.0 0.05 492181.0 97500.0 0.55 0.428 0.769 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K09 compound treatment 64224.0 -330000.0 -1.96 80535.0 -314000.0 -1.79 -2.6528 -0.9989 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K10 compound treatment 140635.0 -254000.0 -1.51 320931.0 -73800.0 -0.42 -1.3646 -0.8706 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K11 compound treatment 40473.0 -354000.0 -2.11 70535.0 -324000.0 -1.84 -2.793 -0.9978 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K12 compound treatment 75025.0 -319000.0 -1.9 73569.0 -321000.0 -1.83 -2.6353 -0.9998 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K13 compound treatment 134936.0 -259000.0 -1.54 435235.0 40500.0 0.23 -0.9289 -0.595 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K14 compound treatment 103858.0 -291000.0 -1.73 95316.0 -299000.0 -1.7 -2.4266 -1.0 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K15 mock treatment 289303.0 -105000.0 -0.63 489229.0 94500.0 0.54 -0.0622 -0.0754 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K16 mock treatment 402942.0 8550.0 0.05 420701.0 26000.0 0.15 0.1405 0.8988 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K17 compound treatment 60933.0 -333000.0 -1.98 63283.0 -331000.0 -1.88 -2.736 -0.9997 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K18 compound treatment 48433.0 -346000.0 -2.06 68635.0 -326000.0 -1.85 -2.7671 -0.9986 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K19 compound treatment 345093.0 -49300.0 -0.29 294551.0 -100000.0 -0.57 -0.6102 -0.9524 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K20 compound treatment 62605.0 -332000.0 -1.97 63431.0 -331000.0 -1.88 -2.7284 -0.9997 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K21 compound treatment 204567.0 -190000.0 -1.13 194764.0 -200000.0 -1.14 -1.6029 -1.0 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K22 compound treatment 61378.0 -333000.0 -1.98 77548.0 -317000.0 -1.8 -2.6768 -0.9989 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K23 mock treatment 95327.0 -299000.0 -1.78 208159.0 -187000.0 -1.06 -2.0087 -0.9694 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 K24 mock treatment 312807.0 -81600.0 -0.49 185497.0 -209000.0 -1.19 -1.1846 -0.9219 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L01 compound treatment 90509.0 -304000.0 -1.81 105555.0 -289000.0 -1.64 -2.4416 -0.9989 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L02 compound treatment 540919.0 147000.0 0.87 532293.0 138000.0 0.78 1.1699 0.9985 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L03 compound treatment 282522.0 -112000.0 -0.67 320479.0 -74200.0 -0.42 -0.7693 -0.9758 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L04 compound treatment 522238.0 128000.0 0.76 499235.0 105000.0 0.59 0.9583 0.9925 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L05 compound treatment 379983.0 -14400.0 -0.09 408075.0 13400.0 0.08 -0.0069 -0.0602 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L06 compound treatment 69843.0 -325000.0 -1.93 94269.0 -300000.0 -1.71 -2.5739 -0.9981 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L07 mock treatment 532530.0 138000.0 0.82 507013.0 112000.0 0.64 1.0329 0.9922 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L08 mock treatment 479746.0 85400.0 0.51 458906.0 64200.0 0.37 0.6173 0.9869 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L09 compound treatment 148915.0 -245000.0 -1.46 267453.0 -127000.0 -0.72 -1.5448 -0.9475 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L10 compound treatment 205163.0 -189000.0 -1.13 211162.0 -184000.0 -1.04 -1.5344 -0.9993 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L11 compound treatment 86923.0 -307000.0 -1.83 35258.0 -359000.0 -2.04 -2.7393 -0.9985 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L12 compound treatment 494415.0 100000.0 0.6 499314.0 105000.0 0.59 0.8415 1.0 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L13 compound treatment 66601.0 -328000.0 -1.95 98440.0 -296000.0 -1.68 -2.5708 -0.9973 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L14 compound treatment 377933.0 -16500.0 -0.1 354876.0 -39800.0 -0.23 -0.2294 -0.9297 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L15 mock treatment 492492.0 98100.0 0.58 540883.0 146000.0 0.83 1.0006 0.9851 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L16 mock treatment 480512.0 86100.0 0.51 294387.0 -100000.0 -0.57 -0.041 -0.0535 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L17 compound treatment 63239.0 -331000.0 -1.97 49060.0 -346000.0 -1.97 -2.7835 -1.0 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L18 compound treatment 431172.0 36800.0 0.22 521091.0 126000.0 0.72 0.663 0.8825 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L19 compound treatment 61868.0 -333000.0 -1.98 62924.0 -332000.0 -1.89 -2.7335 -0.9997 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L20 compound treatment 287285.0 -107000.0 -0.64 465623.0 70900.0 0.4 -0.1656 -0.2195 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L21 compound treatment 44635.0 -350000.0 -2.08 101049.0 -294000.0 -1.67 -2.6527 -0.994 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L22 compound treatment 381779.0 -12600.0 -0.08 377262.0 -17500.0 -0.1 -0.1232 -0.9905 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L23 mock treatment 197601.0 -197000.0 -1.17 459700.0 65000.0 0.37 -0.5668 -0.4615 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 L24 mock treatment 520333.0 126000.0 0.75 497890.0 103000.0 0.59 0.9449 0.9927 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M01 compound treatment 74143.0 -320000.0 -1.91 65491.0 -329000.0 -1.87 -2.6715 -1.0 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M02 compound treatment 75214.0 -319000.0 -1.9 66483.0 -328000.0 -1.87 -2.663 -1.0 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M03 compound treatment 64742.0 -330000.0 -1.96 78068.0 -317000.0 -1.8 -2.6605 -0.9991 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M04 compound treatment 66077.0 -328000.0 -1.95 69370.0 -325000.0 -1.85 -2.6899 -0.9996 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M05 compound treatment 46863.0 -348000.0 -2.07 59754.0 -335000.0 -1.9 -2.8094 -0.9992 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M06 compound treatment 18857.0 -376000.0 -2.23 70499.0 -324000.0 -1.84 -2.8841 -0.9954 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M07 compound treatment 28806.0 -366000.0 -2.18 65273.0 -329000.0 -1.87 -2.8632 -0.9972 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M08 compound treatment 70477.0 -324000.0 -1.93 83162.0 -312000.0 -1.77 -2.6159 -0.9991 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M09 mock treatment 476449.0 82100.0 0.49 552380.0 158000.0 0.9 0.9793 0.9592 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M10 mock treatment 396875.0 2480.0 0.01 379806.0 -14900.0 -0.08 -0.0495 -0.5751 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M11 compound treatment 510911.0 117000.0 0.69 220834.0 -174000.0 -0.99 -0.2088 -0.1729 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M12 compound treatment 74310.0 -320000.0 -1.9 64723.0 -330000.0 -1.88 -2.6739 -1.0 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M13 mock treatment 518243.0 124000.0 0.74 496153.0 101000.0 0.58 0.9291 0.9926 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M14 mock treatment 382532.0 -11900.0 -0.07 418088.0 23400.0 0.13 0.0441 0.293 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M15 compound treatment 58433.0 -336000.0 -2.0 62846.0 -332000.0 -1.89 -2.7483 -0.9996 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M16 compound treatment 62004.0 -332000.0 -1.98 67061.0 -328000.0 -1.86 -2.7163 -0.9996 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M17 compound treatment 41100.0 -353000.0 -2.1 94416.0 -300000.0 -1.71 -2.6943 -0.9947 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M18 compound treatment 87477.0 -307000.0 -1.83 87061.0 -308000.0 -1.75 -2.5287 -0.9998 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M19 compound treatment 279353.0 -115000.0 -0.68 340515.0 -54200.0 -0.31 -0.702 -0.9351 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M20 compound treatment 57152.0 -337000.0 -2.01 69661.0 -325000.0 -1.85 -2.7263 -0.9992 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M21 compound treatment 189233.0 -205000.0 -1.22 139968.0 -255000.0 -1.45 -1.8877 -0.9964 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M22 compound treatment 137125.0 -257000.0 -1.53 129855.0 -265000.0 -1.51 -2.1477 -1.0 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M23 compound treatment 269323.0 -125000.0 -0.74 272935.0 -122000.0 -0.69 -1.016 -0.9994 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 M24 compound treatment 67485.0 -327000.0 -1.95 64801.0 -330000.0 -1.88 -2.7023 -0.9998 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N01 compound treatment 302605.0 -91800.0 -0.55 123094.0 -272000.0 -1.54 -1.4785 -0.9024 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N02 compound treatment 415545.0 21200.0 0.13 420120.0 25400.0 0.14 0.1912 0.9976 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N03 compound treatment 435145.0 40800.0 0.24 535479.0 141000.0 0.8 0.7375 0.8818 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N04 compound treatment 541743.0 147000.0 0.88 505250.0 111000.0 0.63 1.0646 0.9867 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N05 compound treatment 292664.0 -102000.0 -0.61 386395.0 -8320.0 -0.05 -0.4615 -0.76 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N06 compound treatment 505973.0 112000.0 0.66 291725.0 -103000.0 -0.59 0.0554 0.0626 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N07 compound treatment 300788.0 -93600.0 -0.56 286412.0 -108000.0 -0.62 -0.8294 -0.9987 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N08 compound treatment 387289.0 -7100.0 -0.04 361313.0 -33400.0 -0.19 -0.1642 -0.8438 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N09 mock treatment 292842.0 -102000.0 -0.6 126849.0 -268000.0 -1.52 -1.5045 -0.918 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N10 mock treatment 526791.0 132000.0 0.79 228225.0 -166000.0 -0.95 -0.1123 -0.0912 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N11 compound treatment 105091.0 -289000.0 -1.72 57992.0 -337000.0 -1.91 -2.5715 -0.9986 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N12 compound treatment 121213.0 -273000.0 -1.63 169283.0 -225000.0 -1.28 -2.0561 -0.9931 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N13 mock treatment 488781.0 94400.0 0.56 519691.0 125000.0 0.71 0.8998 0.9932 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N14 mock treatment 549561.0 155000.0 0.92 542624.0 148000.0 0.84 1.2478 0.9989 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N15 compound treatment 83491.0 -311000.0 -1.85 89275.0 -305000.0 -1.74 -2.5366 -0.9995 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N16 compound treatment 451221.0 56800.0 0.34 260255.0 -134000.0 -0.76 -0.3015 -0.3606 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N17 compound treatment 65461.0 -329000.0 -1.96 65866.0 -329000.0 -1.87 -2.7066 -0.9997 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N18 compound treatment 441729.0 47300.0 0.28 463437.0 68700.0 0.39 0.4756 0.9871 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N19 compound treatment 39348.0 -355000.0 -2.11 144312.0 -250000.0 -1.42 -2.501 -0.9815 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N20 compound treatment 713948.0 320000.0 1.9 461402.0 66700.0 0.38 1.613 0.8317 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N21 compound treatment 158363.0 -236000.0 -1.4 167814.0 -227000.0 -1.29 -1.9057 -0.9991 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N22 compound treatment 152605.0 -242000.0 -1.44 114789.0 -280000.0 -1.59 -2.1431 -0.9987 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N23 compound treatment 295801.0 -98600.0 -0.59 262892.0 -132000.0 -0.75 -0.945 -0.9927 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 N24 compound treatment 483171.0 88800.0 0.53 525206.0 130000.0 0.74 0.8983 0.9861 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O01 compound treatment 581985.0 188000.0 1.12 603842.0 209000.0 1.19 1.6304 0.9995 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O02 compound treatment 262187.0 -132000.0 -0.79 238628.0 -156000.0 -0.89 -1.184 -0.9982 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O03 compound treatment 164707.0 -230000.0 -1.37 194715.0 -200000.0 -1.14 -1.7708 -0.9958 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O04 compound treatment 73968.0 -320000.0 -1.91 76485.0 -318000.0 -1.81 -2.6281 -0.9997 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O05 compound treatment 59806.0 -335000.0 -1.99 61673.0 -333000.0 -1.89 -2.7472 -0.9997 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O06 compound treatment 81034.0 -313000.0 -1.86 68916.0 -326000.0 -1.85 -2.6288 -1.0 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O07 compound treatment 56882.0 -338000.0 -2.01 63464.0 -331000.0 -1.88 -2.7523 -0.9995 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O08 compound treatment 291741.0 -103000.0 -0.61 119368.0 -275000.0 -1.57 -1.5392 -0.9158 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O09 compound treatment 68200.0 -326000.0 -1.94 73528.0 -321000.0 -1.83 -2.6642 -0.9995 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O10 compound treatment 86921.0 -307000.0 -1.83 86546.0 -308000.0 -1.75 -2.5331 -0.9998 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O11 mock treatment 243535.0 -151000.0 -0.9 597203.0 202000.0 1.15 0.1794 0.1229 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O12 mock treatment 510619.0 116000.0 0.69 526355.0 132000.0 0.75 1.0185 0.9992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O13 compound treatment 35793.0 -359000.0 -2.13 83280.0 -311000.0 -1.77 -2.7614 -0.9957 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O14 compound treatment 61275.0 -333000.0 -1.98 74556.0 -320000.0 -1.82 -2.6892 -0.9991 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O15 compound treatment 56942.0 -337000.0 -2.01 67513.0 -327000.0 -1.86 -2.7358 -0.9993 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O16 compound treatment 61064.0 -333000.0 -1.98 62619.0 -332000.0 -1.89 -2.7381 -0.9997 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O17 compound treatment 241732.0 -153000.0 -0.91 205807.0 -189000.0 -1.07 -1.402 -0.9965 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O18 compound treatment 31635.0 -363000.0 -2.16 268663.0 -126000.0 -0.72 -2.0334 -0.8939 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O19 compound treatment 33840.0 -361000.0 -2.15 68761.0 -326000.0 -1.85 -2.828 -0.9973 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O20 compound treatment 68477.0 -326000.0 -1.94 39142.0 -356000.0 -2.02 -2.8013 -0.9998 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O21 compound treatment 106987.0 -287000.0 -1.71 145383.0 -249000.0 -1.42 -2.2121 -0.9957 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O22 compound treatment 20343.0 -374000.0 -2.23 55820.0 -339000.0 -1.93 -2.9368 -0.9974 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O23 compound treatment 62891.0 -331000.0 -1.97 61628.0 -333000.0 -1.89 -2.7344 -0.9998 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 O24 compound treatment 75173.0 -319000.0 -1.9 82019.0 -313000.0 -1.78 -2.6007 -0.9995 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P01 compound treatment 103173.0 -291000.0 -1.73 140496.0 -254000.0 -1.45 -2.2478 -0.9959 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P02 compound treatment 493132.0 98700.0 0.59 519190.0 124000.0 0.71 0.9161 0.9957 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P03 compound treatment 363972.0 -30400.0 -0.18 353044.0 -41700.0 -0.24 -0.2956 -0.9912 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P04 compound treatment 87121.0 -307000.0 -1.83 88323.0 -306000.0 -1.74 -2.5251 -0.9997 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P05 compound treatment 73556.0 -321000.0 -1.91 64605.0 -330000.0 -1.88 -2.6776 -1.0 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P06 compound treatment 259004.0 -135000.0 -0.81 319670.0 -75000.0 -0.43 -0.8715 -0.9558 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P07 compound treatment 540774.0 146000.0 0.87 425220.0 30500.0 0.17 0.7387 0.8316 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P08 compound treatment 321081.0 -73300.0 -0.44 499904.0 105000.0 0.6 0.1145 0.1546 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P09 compound treatment 336950.0 -57400.0 -0.34 357687.0 -37000.0 -0.21 -0.3906 -0.9729 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P10 compound treatment 246043.0 -148000.0 -0.88 328805.0 -65900.0 -0.37 -0.8893 -0.9272 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P11 mock treatment 538038.0 144000.0 0.85 522582.0 128000.0 0.73 1.1187 0.9968 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P12 mock treatment 554862.0 160000.0 0.96 524704.0 130000.0 0.74 1.198 0.992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P13 compound treatment 308778.0 -85600.0 -0.51 264732.0 -130000.0 -0.74 -0.883 -0.9835 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P14 compound treatment 556659.0 162000.0 0.97 515579.0 121000.0 0.69 1.1689 0.9861 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P15 compound treatment 320739.0 -73700.0 -0.44 298826.0 -95900.0 -0.55 -0.6955 -0.9941 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P16 compound treatment 540500.0 146000.0 0.87 547151.0 152000.0 0.87 1.2278 1.0 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P17 compound treatment 87886.0 -307000.0 -1.82 59817.0 -335000.0 -1.9 -2.6365 -0.9998 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P18 compound treatment 305756.0 -88600.0 -0.53 260309.0 -134000.0 -0.76 -0.9135 -0.9836 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P19 compound treatment 29705.0 -365000.0 -2.17 173362.0 -221000.0 -1.26 -2.4248 -0.9664 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P20 compound treatment 65074.0 -329000.0 -1.96 69327.0 -325000.0 -1.85 -2.6943 -0.9996 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P21 compound treatment 338491.0 -55900.0 -0.33 282422.0 -112000.0 -0.64 -0.6868 -0.9538 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P22 compound treatment 374355.0 -20000.0 -0.12 389463.0 -5250.0 -0.03 -0.1054 -0.8577 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P23 compound treatment 64372.0 -330000.0 -1.96 63634.0 -331000.0 -1.88 -2.7201 -0.9998 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2102 P24 compound treatment 655846.0 261000.0 1.56 585039.0 190000.0 1.08 1.8656 0.9843 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A01 compound treatment 141650.0 -302000.0 -1.8 94871.0 -396000.0 -2.25 -2.8649 -0.9938 3070297 PK04_103001 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A02 compound treatment 248044.0 -196000.0 -1.17 253353.0 -238000.0 -1.35 -1.7798 -0.9973 3189402 PK04_103002 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A03 compound treatment 384122.0 -59800.0 -0.36 308933.0 -182000.0 -1.03 -0.9837 -0.8987 3070298 PK04_103003 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A04 compound treatment 320566.0 -123000.0 -0.73 326382.0 -165000.0 -0.94 -1.181 -0.9928 3189403 PK04_103004 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A05 compound treatment 164210.0 -280000.0 -1.66 136021.0 -355000.0 -2.02 -2.6045 -0.9954 3070299 PK04_103005 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A06 compound treatment 396407.0 -47600.0 -0.28 501450.0 10500.0 0.06 -0.1579 -0.5456 3189404 PK04_103006 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A07 compound treatment 271886.0 -172000.0 -1.02 392717.0 -98200.0 -0.56 -1.1191 -0.9593 3070300 PK04_103007 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A08 compound treatment 170556.0 -273000.0 -1.63 411708.0 -79200.0 -0.45 -1.4692 -0.8701 3189405 PK04_103008 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A09 compound treatment 319574.0 -124000.0 -0.74 465995.0 -24900.0 -0.14 -0.6238 -0.8275 3189406 PK04_103009 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A10 compound treatment 339030.0 -105000.0 -0.62 436746.0 -54200.0 -0.31 -0.6595 -0.947 3070355 PK04_103010 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A11 compound treatment 85815.0 -358000.0 -2.13 135072.0 -356000.0 -2.02 -2.9382 -0.9997 3189407 PK04_103011 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A12 compound treatment 166274.0 -278000.0 -1.65 192037.0 -299000.0 -1.7 -2.3705 -0.9999 3189408 PK04_103012 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A13 mock treatment 392004.0 -52000.0 -0.31 218743.0 -272000.0 -1.55 -1.3132 -0.8319 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A14 mock treatment 453009.0 9040.0 0.05 452503.0 -38400.0 -0.22 -0.1165 -0.5176 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A15 compound treatment 64567.0 -379000.0 -2.26 68627.0 -422000.0 -2.4 -3.2948 -0.9995 3070356 PK04_103013 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A16 compound treatment 156856.0 -287000.0 -1.71 242005.0 -249000.0 -1.42 -2.2092 -0.9956 3189409 PK04_103014 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A17 compound treatment 294196.0 -150000.0 -0.89 424219.0 -66700.0 -0.38 -0.8986 -0.9275 3070357 PK04_103015 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A18 compound treatment 115210.0 -329000.0 -1.96 73362.0 -418000.0 -2.37 -3.0626 -0.9954 3189410 PK04_103016 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A19 compound treatment 41480.0 -402000.0 -2.4 68267.0 -423000.0 -2.4 -3.3934 -1.0 3070358 PK04_103017 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A20 compound treatment 471886.0 27900.0 0.17 164530.0 -326000.0 -1.86 -1.195 -0.6413 3189411 PK04_103018 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A21 compound treatment 245472.0 -198000.0 -1.18 288462.0 -202000.0 -1.15 -1.6495 -0.9999 3070359 PK04_103019 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A22 compound treatment 382342.0 -61600.0 -0.37 216504.0 -274000.0 -1.56 -1.3629 -0.8501 3189412 PK04_103020 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A23 compound treatment 154044.0 -290000.0 -1.73 115686.0 -375000.0 -2.13 -2.729 -0.9944 3070360 PK04_103021 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 A24 compound treatment 450646.0 6680.0 0.04 507300.0 16400.0 0.09 0.0939 0.9279 3189413 PK04_103022 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B01 compound treatment 227231.0 -217000.0 -1.29 511419.0 20500.0 0.12 -0.8297 -0.6406 3189525 PK04_103023 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B02 compound treatment 373319.0 -70700.0 -0.42 486902.0 -4030.0 -0.02 -0.3135 -0.7445 3070361 PK04_103024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B03 compound treatment 323517.0 -120000.0 -0.72 252284.0 -239000.0 -1.36 -1.4665 -0.9555 3189526 PK04_103025 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B04 compound treatment 365027.0 -78900.0 -0.47 455246.0 -35700.0 -0.2 -0.4757 -0.9295 3189527 PK04_103026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B05 compound treatment 190424.0 -254000.0 -1.51 491114.0 183.0 0.0 -1.0663 -0.7066 3070362 PK04_103027 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B06 compound treatment 180125.0 -264000.0 -1.57 282309.0 -209000.0 -1.19 -1.9492 -0.9904 3189528 PK04_103028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B07 compound treatment 337839.0 -106000.0 -0.63 455796.0 -35100.0 -0.2 -0.5879 -0.8874 3070363 PK04_103029 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B08 compound treatment 453078.0 9110.0 0.05 614532.0 124000.0 0.7 0.5353 0.7594 3189529 PK04_103030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B09 compound treatment 82090.0 -362000.0 -2.15 192221.0 -299000.0 -1.7 -2.7241 -0.9931 3189530 PK04_103031 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B10 compound treatment 437364.0 -6610.0 -0.04 575510.0 84600.0 0.48 0.3123 0.6471 3070364 PK04_103032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B11 compound treatment 126752.0 -317000.0 -1.89 235579.0 -255000.0 -1.45 -2.3618 -0.9916 3189531 PK04_103033 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B12 compound treatment 461845.0 17900.0 0.11 611865.0 121000.0 0.69 0.5615 0.8069 3189532 PK04_103034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B13 mock treatment 435926.0 -8040.0 -0.05 681957.0 191000.0 1.09 0.7343 0.6753 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B14 mock treatment 325997.0 -118000.0 -0.7 371260.0 -120000.0 -0.68 -0.9777 -0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B15 compound treatment 127946.0 -316000.0 -1.88 204389.0 -287000.0 -1.63 -2.4821 -0.9974 3070365 PK04_103035 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B16 compound treatment 405027.0 -38900.0 -0.23 434615.0 -56300.0 -0.32 -0.3903 -0.9874 3189533 PK04_103036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B17 compound treatment 279952.0 -164000.0 -0.98 273487.0 -217000.0 -1.24 -1.5646 -0.9931 3070366 PK04_103037 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B18 compound treatment 215333.0 -229000.0 -1.36 84734.0 -406000.0 -2.31 -2.5955 -0.9682 3189534 PK04_103038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B19 compound treatment 348539.0 -95400.0 -0.57 430535.0 -60400.0 -0.34 -0.6445 -0.971 3189535 PK04_103039 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B20 compound treatment 532539.0 88600.0 0.53 191828.0 -299000.0 -1.7 -0.83 -0.4661 3070367 PK04_103040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B21 compound treatment 461991.0 18000.0 0.11 475533.0 -15400.0 -0.09 0.0139 0.1005 3189536 PK04_103041 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B22 compound treatment 472703.0 28700.0 0.17 241890.0 -249000.0 -1.42 -0.8805 -0.6172 3189537 PK04_103042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B23 compound treatment 300194.0 -144000.0 -0.86 264220.0 -227000.0 -1.29 -1.5167 -0.9802 3070368 PK04_103043 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 B24 compound treatment 364331.0 -79600.0 -0.47 183589.0 -307000.0 -1.75 -1.571 -0.8675 3189538 PK04_103044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C01 compound treatment 569159.0 125000.0 0.75 523293.0 32400.0 0.18 0.657 0.856 3070369 PK04_103045 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C02 compound treatment 380920.0 -63100.0 -0.38 369675.0 -121000.0 -0.69 -0.7529 -0.9591 3189539 PK04_103046 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C03 compound treatment 68974.0 -375000.0 -2.23 90103.0 -401000.0 -2.28 -3.1899 -0.9999 3189540 PK04_103047 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C04 compound treatment 211894.0 -232000.0 -1.38 193030.0 -298000.0 -1.69 -2.1745 -0.9949 3070370 PK04_103048 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C05 compound treatment 324287.0 -120000.0 -0.71 259563.0 -231000.0 -1.32 -1.434 -0.9585 3189541 PK04_103049 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C06 compound treatment 365233.0 -78700.0 -0.47 466435.0 -24500.0 -0.14 -0.4299 -0.8793 3189542 PK04_103050 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C07 compound treatment 220199.0 -224000.0 -1.33 265762.0 -225000.0 -1.28 -1.8471 -0.9998 3070371 PK04_103051 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C08 compound treatment 281516.0 -162000.0 -0.97 347960.0 -143000.0 -0.81 -1.2586 -0.9963 3189543 PK04_103052 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C09 compound treatment 61575.0 -382000.0 -2.28 53230.0 -438000.0 -2.49 -3.3693 -0.999 3070372 PK04_103053 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C10 compound treatment 56850.0 -387000.0 -2.3 106181.0 -385000.0 -2.19 -3.1762 -0.9997 3189544 PK04_103054 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C11 mock treatment 156341.0 -288000.0 -1.71 594432.0 104000.0 0.59 -0.7942 -0.4388 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C12 mock treatment 404210.0 -39800.0 -0.24 517567.0 26600.0 0.15 -0.0602 -0.2143 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C13 compound treatment 91198.0 -353000.0 -2.1 96200.0 -395000.0 -2.24 -3.0718 -0.9994 3189545 PK04_103055 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C14 compound treatment 60990.0 -383000.0 -2.28 61505.0 -429000.0 -2.44 -3.3385 -0.9994 3189546 PK04_103056 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C15 mock treatment 453858.0 9890.0 0.06 457551.0 -33400.0 -0.19 -0.0926 -0.466 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C16 mock treatment 460978.0 17000.0 0.1 562403.0 71500.0 0.41 0.359 0.857 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C17 compound treatment 291005.0 -153000.0 -0.91 371686.0 -119000.0 -0.68 -1.1232 -0.9895 3070427 PK04_103057 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C18 compound treatment 218210.0 -226000.0 -1.34 267156.0 -224000.0 -1.27 -1.8499 -0.9996 3189660 PK04_103058 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C19 compound treatment 53839.0 -390000.0 -2.32 57604.0 -433000.0 -2.46 -3.3843 -0.9996 3070428 PK04_103059 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C20 compound treatment 61598.0 -382000.0 -2.28 72050.0 -419000.0 -2.38 -3.2935 -0.9997 3189661 PK04_103060 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C21 compound treatment 56005.0 -388000.0 -2.31 42558.0 -448000.0 -2.55 -3.4356 -0.9988 3189662 PK04_103061 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C22 compound treatment 405860.0 -38100.0 -0.23 244863.0 -246000.0 -1.4 -1.1499 -0.8111 3070429 PK04_103062 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C23 compound treatment 414457.0 -29500.0 -0.18 172119.0 -319000.0 -1.81 -1.4062 -0.772 3189663 PK04_103063 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 C24 compound treatment 620555.0 177000.0 1.05 299674.0 -191000.0 -1.09 -0.026 -0.0172 3189664 PK04_103064 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D01 compound treatment 246519.0 -197000.0 -1.18 254692.0 -236000.0 -1.34 -1.7809 -0.9978 3070430 PK04_103065 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D02 compound treatment 69999.0 -374000.0 -2.23 66337.0 -425000.0 -2.41 -3.2811 -0.9992 3189665 PK04_103066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D03 compound treatment 419082.0 -24900.0 -0.15 445037.0 -45900.0 -0.26 -0.2893 -0.964 3070431 PK04_103067 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D04 compound treatment 212686.0 -231000.0 -1.38 272246.0 -219000.0 -1.24 -1.8527 -0.9987 3189666 PK04_103068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D05 compound treatment 118561.0 -325000.0 -1.94 171345.0 -320000.0 -1.82 -2.6545 -0.9995 3189667 PK04_103069 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D06 compound treatment 72106.0 -372000.0 -2.21 71088.0 -420000.0 -2.39 -3.2532 -0.9993 3189668 PK04_103070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D07 compound treatment 143941.0 -300000.0 -1.79 179178.0 -312000.0 -1.77 -2.5162 -1.0 3070432 PK04_103071 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D08 compound treatment 413957.0 -30000.0 -0.18 479526.0 -11400.0 -0.06 -0.1722 -0.906 3189669 PK04_103072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D09 compound treatment 200016.0 -244000.0 -1.45 207467.0 -283000.0 -1.61 -2.1665 -0.9986 3070433 PK04_103073 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D10 compound treatment 449650.0 5680.0 0.03 477002.0 -13900.0 -0.08 -0.0321 -0.3728 3189670 PK04_103074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D11 mock treatment 446530.0 2560.0 0.02 558656.0 67700.0 0.39 0.2831 0.7345 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D12 mock treatment 269601.0 -174000.0 -1.04 293197.0 -198000.0 -1.12 -1.5289 -0.9992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D13 compound treatment 65005.0 -379000.0 -2.26 91177.0 -400000.0 -2.27 -3.2023 -1.0 3189671 PK04_103075 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D14 compound treatment 127645.0 -316000.0 -1.88 159037.0 -332000.0 -1.89 -2.6658 -1.0 3070434 PK04_103076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D15 mock treatment 268521.0 -175000.0 -1.04 409207.0 -81700.0 -0.46 -1.067 -0.9335 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D16 mock treatment 215142.0 -229000.0 -1.36 267036.0 -224000.0 -1.27 -1.8633 -0.9994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D17 compound treatment 83041.0 -361000.0 -2.15 97993.0 -393000.0 -2.23 -3.099 -0.9998 3189672 PK04_103077 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D18 compound treatment 95938.0 -348000.0 -2.07 113039.0 -378000.0 -2.15 -2.9842 -0.9998 3189673 PK04_103078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D19 compound treatment 93050.0 -351000.0 -2.09 68282.0 -423000.0 -2.4 -3.1763 -0.9975 3070435 PK04_103079 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D20 compound treatment 144220.0 -300000.0 -1.78 154483.0 -336000.0 -1.91 -2.6143 -0.9994 3189674 PK04_103080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D21 compound treatment 187141.0 -257000.0 -1.53 143278.0 -348000.0 -1.98 -2.4788 -0.9919 3189675 PK04_103081 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D22 compound treatment 69380.0 -375000.0 -2.23 68735.0 -422000.0 -2.4 -3.2741 -0.9993 3070436 PK04_103082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D23 compound treatment 335784.0 -108000.0 -0.64 296697.0 -194000.0 -1.1 -1.2363 -0.967 3189676 PK04_103083 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 D24 compound treatment 530772.0 86800.0 0.52 192955.0 -298000.0 -1.69 -0.8329 -0.4702 3070437 PK04_103084 CN1CCC(=CC1C2CC2)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E01 mock treatment 470586.0 26600.0 0.16 655779.0 165000.0 0.94 0.7749 0.815 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E02 mock treatment 522160.0 78200.0 0.47 526574.0 35600.0 0.2 0.4724 0.9307 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E03 compound treatment 413427.0 -30500.0 -0.18 515269.0 24300.0 0.14 -0.0307 -0.1342 3189677 PK04_103085 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E04 compound treatment 320915.0 -123000.0 -0.73 282491.0 -208000.0 -1.19 -1.356 -0.9732 3070438 PK04_103086 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E05 compound treatment 435396.0 -8570.0 -0.05 434405.0 -56500.0 -0.32 -0.2634 -0.8092 3189678 PK04_103087 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E06 compound treatment 199203.0 -245000.0 -1.46 247529.0 -243000.0 -1.38 -2.0088 -0.9997 3189679 PK04_103088 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E07 compound treatment 456677.0 12700.0 0.08 535218.0 44300.0 0.25 0.2316 0.8806 3189680 PK04_103089 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E08 compound treatment 217858.0 -226000.0 -1.35 209398.0 -282000.0 -1.6 -2.0836 -0.9963 3070490 PK04_103090 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E09 mock treatment 492010.0 48000.0 0.29 282003.0 -209000.0 -1.19 -0.638 -0.5221 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E10 mock treatment 407534.0 -36400.0 -0.22 511622.0 20700.0 0.12 -0.0701 -0.2843 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E11 compound treatment 59976.0 -384000.0 -2.29 62258.0 -429000.0 -2.44 -3.3397 -0.9995 3187704 PK04_103091 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E12 compound treatment 63519.0 -380000.0 -2.26 62948.0 -428000.0 -2.43 -3.322 -0.9993 3070491 PK04_103092 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E13 compound treatment 65574.0 -378000.0 -2.25 65569.0 -425000.0 -2.42 -3.3028 -0.9994 3187705 PK04_103093 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E14 compound treatment 60827.0 -383000.0 -2.28 53970.0 -437000.0 -2.48 -3.3695 -0.9991 3187706 PK04_103094 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E15 compound treatment 214841.0 -229000.0 -1.36 250262.0 -241000.0 -1.37 -1.932 -1.0 3070492 PK04_103095 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E16 compound treatment 69797.0 -374000.0 -2.23 190334.0 -301000.0 -1.71 -2.7834 -0.9915 3187707 PK04_103096 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E17 mock treatment 487449.0 43500.0 0.26 364474.0 -126000.0 -0.72 -0.3255 -0.4259 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E18 mock treatment 502427.0 58500.0 0.35 449837.0 -41100.0 -0.23 0.0808 0.1927 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E19 compound treatment 56341.0 -388000.0 -2.31 63466.0 -427000.0 -2.43 -3.3502 -0.9997 3070493 PK04_103097 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E20 compound treatment 363981.0 -80000.0 -0.48 360583.0 -130000.0 -0.74 -0.8608 -0.9771 3187708 PK04_103098 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E21 compound treatment 173601.0 -270000.0 -1.61 166970.0 -324000.0 -1.84 -2.4405 -0.9977 3187709 PK04_103099 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E22 compound treatment 98507.0 -345000.0 -2.06 73329.0 -418000.0 -2.37 -3.133 -0.9974 3070494 PK04_103100 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E23 compound treatment 62416.0 -382000.0 -2.27 65311.0 -426000.0 -2.42 -3.3172 -0.9995 3187710 PK04_103101 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 E24 compound treatment 363945.0 -80000.0 -0.48 194900.0 -296000.0 -1.68 -1.5272 -0.8729 3187711 PK04_103102 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F01 mock treatment 404599.0 -39400.0 -0.23 777801.0 287000.0 1.63 0.9879 0.5994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F02 mock treatment 354739.0 -89200.0 -0.53 406074.0 -84900.0 -0.48 -0.7167 -0.9989 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F03 compound treatment 380005.0 -64000.0 -0.38 517036.0 26100.0 0.15 -0.1642 -0.4019 3070495 PK04_103103 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F04 compound treatment 98222.0 -346000.0 -2.06 108572.0 -382000.0 -2.17 -2.9925 -0.9996 3187712 PK04_103104 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F05 compound treatment 131157.0 -313000.0 -1.86 328673.0 -162000.0 -0.92 -1.9689 -0.9476 3070496 PK04_103105 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F06 compound treatment 429537.0 -14400.0 -0.09 590744.0 99800.0 0.57 0.3406 0.5933 3187713 PK04_103106 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F07 compound treatment 335711.0 -108000.0 -0.64 340588.0 -150000.0 -0.85 -1.0601 -0.9903 3070497 PK04_103107 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F08 compound treatment 420039.0 -23900.0 -0.14 517500.0 26600.0 0.15 0.0061 0.0295 3187714 PK04_103108 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F09 mock treatment 491607.0 47600.0 0.28 551337.0 60400.0 0.34 0.4434 0.9955 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F10 mock treatment 273297.0 -171000.0 -1.02 299952.0 -191000.0 -1.09 -1.4862 -0.9994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F11 compound treatment 74287.0 -370000.0 -2.2 87750.0 -403000.0 -2.29 -3.177 -0.9998 3187715 PK04_103109 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F12 compound treatment 378034.0 -65900.0 -0.39 471589.0 -19300.0 -0.11 -0.3553 -0.8717 3070498 PK04_103110 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F13 compound treatment 137600.0 -306000.0 -1.82 183085.0 -308000.0 -1.75 -2.5272 -0.9998 3187716 PK04_103111 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F14 compound treatment 131453.0 -313000.0 -1.86 118914.0 -372000.0 -2.12 -2.8111 -0.9979 3070499 PK04_103112 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F15 compound treatment 242201.0 -202000.0 -1.2 318020.0 -173000.0 -0.98 -1.5444 -0.9951 3187717 PK04_103113 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F16 compound treatment 476260.0 32300.0 0.19 322341.0 -169000.0 -0.96 -0.542 -0.5543 3187718 PK04_103114 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F17 mock treatment 428433.0 -15500.0 -0.09 179049.0 -312000.0 -1.77 -1.3195 -0.743 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F18 mock treatment 252291.0 -192000.0 -1.14 320728.0 -170000.0 -0.97 -1.4911 -0.9967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F19 compound treatment 55023.0 -389000.0 -2.31 37635.0 -453000.0 -2.58 -3.4596 -0.9986 3070500 PK04_103115 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F20 compound treatment 54443.0 -390000.0 -2.32 40302.0 -451000.0 -2.56 -3.4513 -0.9987 3187719 PK04_103116 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F21 compound treatment 169403.0 -275000.0 -1.63 126486.0 -364000.0 -2.07 -2.6209 -0.9931 3070501 PK04_103117 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F22 compound treatment 115447.0 -329000.0 -1.96 46333.0 -445000.0 -2.53 -3.1703 -0.9919 3187720 PK04_103118 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F23 compound treatment 411255.0 -32700.0 -0.19 288789.0 -202000.0 -1.15 -0.9505 -0.8153 3187721 PK04_103119 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 F24 compound treatment 491994.0 48000.0 0.29 517684.0 26800.0 0.15 0.3097 0.9564 3070502 PK04_103120 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G01 compound treatment 78309.0 -366000.0 -2.18 73557.0 -417000.0 -2.37 -3.2171 -0.9991 3187722 PK04_103121 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G02 compound treatment 141768.0 -302000.0 -1.8 241027.0 -250000.0 -1.42 -2.2767 -0.9932 3187723 PK04_103122 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G03 mock treatment 490039.0 46100.0 0.27 524178.0 33200.0 0.19 0.3276 0.9835 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G04 mock treatment 497406.0 53400.0 0.32 566408.0 75500.0 0.43 0.5284 0.9891 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G05 compound treatment 205781.0 -238000.0 -1.42 190106.0 -301000.0 -1.71 -2.212 -0.9956 3070503 PK04_103123 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G06 compound treatment 314252.0 -130000.0 -0.77 313410.0 -178000.0 -1.01 -1.2597 -0.9912 3187724 PK04_103124 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G07 compound treatment 66951.0 -377000.0 -2.24 63803.0 -427000.0 -2.43 -3.3041 -0.9992 3070504 PK04_103125 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G08 compound treatment 63722.0 -380000.0 -2.26 67092.0 -424000.0 -2.41 -3.3045 -0.9995 3187725 PK04_103126 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G09 compound treatment 505552.0 61600.0 0.37 472888.0 -18000.0 -0.1 0.1866 0.4903 3187726 PK04_103127 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G10 compound treatment 112089.0 -332000.0 -1.98 149902.0 -341000.0 -1.94 -2.768 -1.0 3070543 PK04_103128 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G11 compound treatment 384758.0 -59200.0 -0.35 388829.0 -102000.0 -0.58 -0.6597 -0.9714 3187727 PK04_103129 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G12 compound treatment 90279.0 -354000.0 -2.1 98420.0 -393000.0 -2.23 -3.0668 -0.9996 3187844 PK04_103130 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G13 compound treatment 378360.0 -65600.0 -0.39 459924.0 -31000.0 -0.18 -0.4008 -0.9355 3070544 PK04_103131 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G14 compound treatment 63879.0 -380000.0 -2.26 51612.0 -439000.0 -2.5 -3.3661 -0.9988 3187845 PK04_103132 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G15 compound treatment 137454.0 -307000.0 -1.82 214838.0 -276000.0 -1.57 -2.4001 -0.9972 3070545 PK04_103133 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G16 compound treatment 179810.0 -264000.0 -1.57 274493.0 -216000.0 -1.23 -1.982 -0.9927 3187846 PK04_103134 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G17 compound treatment 52957.0 -391000.0 -2.33 67752.0 -423000.0 -2.41 -3.3472 -0.9999 3070546 PK04_103135 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G18 compound treatment 86045.0 -358000.0 -2.13 181343.0 -310000.0 -1.76 -2.7512 -0.9955 3187847 PK04_103136 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G19 mock treatment 454743.0 10800.0 0.06 529626.0 38700.0 0.22 0.2009 0.8767 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G20 mock treatment 503612.0 59600.0 0.35 517991.0 27100.0 0.15 0.3598 0.93 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G21 compound treatment 407160.0 -36800.0 -0.22 211232.0 -280000.0 -1.59 -1.2796 -0.797 3070547 PK04_103137 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G22 compound treatment 251998.0 -192000.0 -1.14 58479.0 -432000.0 -2.46 -2.5468 -0.9392 3187848 PK04_103138 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G23 compound treatment 532386.0 88400.0 0.53 149759.0 -341000.0 -1.94 -0.9998 -0.4974 3070548 PK04_103139 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 G24 compound treatment 390486.0 -53500.0 -0.32 194122.0 -297000.0 -1.69 -1.4186 -0.8259 3187849 PK04_103140 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H01 compound treatment 64249.0 -380000.0 -2.26 71906.0 -419000.0 -2.38 -3.2829 -0.9996 3070549 PK04_103141 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H02 compound treatment 422011.0 -22000.0 -0.13 384130.0 -107000.0 -0.61 -0.5219 -0.84 3187850 PK04_103142 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H03 mock treatment 557281.0 113000.0 0.67 522280.0 31300.0 0.18 0.6029 0.8643 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H04 mock treatment 277402.0 -167000.0 -0.99 302764.0 -188000.0 -1.07 -1.4576 -0.9993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H05 compound treatment 428071.0 -15900.0 -0.09 511994.0 21100.0 0.12 0.0178 0.1165 3187851 PK04_103143 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H06 compound treatment 465456.0 21500.0 0.13 575894.0 85000.0 0.48 0.4321 0.8645 3187852 PK04_103144 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H07 compound treatment 234159.0 -210000.0 -1.25 365137.0 -126000.0 -0.72 -1.3888 -0.9651 3070550 PK04_103145 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H08 compound treatment 493173.0 49200.0 0.29 318459.0 -172000.0 -0.98 -0.4865 -0.4753 3187853 PK04_103146 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H09 compound treatment 414052.0 -29900.0 -0.18 497672.0 6740.0 0.04 -0.0988 -0.5424 3070551 PK04_103147 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H10 compound treatment 33474.0 -410000.0 -2.44 71854.0 -419000.0 -2.38 -3.4127 -0.9999 3070552 PK04_103148 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H11 compound treatment 57181.0 -387000.0 -2.3 57961.0 -433000.0 -2.46 -3.3688 -0.9994 3187854 PK04_103149 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H12 compound treatment 475880.0 31900.0 0.19 526450.0 35500.0 0.2 0.2771 0.9995 3070553 PK04_103150 CN1CCC(=CC1c2cccs2)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H13 compound treatment 77959.0 -366000.0 -2.18 72002.0 -419000.0 -2.38 -3.2249 -0.999 3187855 PK04_103151 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H14 compound treatment 64585.0 -379000.0 -2.26 66217.0 -425000.0 -2.42 -3.3044 -0.9994 3187856 PK04_103152 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H15 compound treatment 113219.0 -331000.0 -1.97 75856.0 -415000.0 -2.36 -3.061 -0.9959 3070554 PK04_103153 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H16 compound treatment 62431.0 -382000.0 -2.27 58408.0 -433000.0 -2.46 -3.3449 -0.9992 3187857 PK04_103154 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H17 compound treatment 51430.0 -393000.0 -2.34 52761.0 -438000.0 -2.49 -3.4139 -0.9995 3187858 PK04_103155 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H18 compound treatment 187638.0 -256000.0 -1.53 273450.0 -217000.0 -1.24 -1.9532 -0.9946 3070555 PK04_103156 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H19 mock treatment 452859.0 8890.0 0.05 537368.0 46400.0 0.26 0.2241 0.8322 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H20 mock treatment 275612.0 -168000.0 -1.0 306799.0 -184000.0 -1.05 -1.4489 -0.9998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H21 compound treatment 443877.0 -93.3 0.0 415199.0 -75700.0 -0.43 -0.3049 -0.708 3187859 PK04_103157 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H22 compound treatment 136142.0 -308000.0 -1.83 75435.0 -415000.0 -2.36 -2.9662 -0.9921 3070556 PK04_103158 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H23 compound treatment 201182.0 -243000.0 -1.44 250922.0 -240000.0 -1.36 -1.9868 -0.9996 3187860 PK04_103159 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 H24 compound treatment 348300.0 -95700.0 -0.57 400340.0 -90600.0 -0.52 -0.7669 -0.9988 3070597 PK04_103160 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I01 compound treatment 506952.0 63000.0 0.37 478219.0 -12700.0 -0.07 0.2139 0.5604 3187861 PK04_103161 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I02 compound treatment 487055.0 43100.0 0.26 436673.0 -54300.0 -0.31 -0.0369 -0.0919 3187862 PK04_103162 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I03 compound treatment 505932.0 62000.0 0.37 492882.0 1950.0 0.01 0.2686 0.7281 3070598 PK04_103163 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I04 compound treatment 531858.0 87900.0 0.52 454900.0 -36000.0 -0.2 0.225 0.4005 3187863 PK04_103164 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I05 mock treatment 520671.0 76700.0 0.46 542451.0 51500.0 0.29 0.5299 0.977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I06 mock treatment 263521.0 -180000.0 -1.07 567195.0 76300.0 0.43 -0.4527 -0.3909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I07 compound treatment 455681.0 11700.0 0.07 467372.0 -23600.0 -0.13 -0.0455 -0.301 3070599 PK04_103165 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I08 compound treatment 427639.0 -16300.0 -0.1 470927.0 -20000.0 -0.11 -0.1492 -0.9969 3187864 PK04_103166 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I09 compound treatment 407741.0 -36200.0 -0.22 465280.0 -25700.0 -0.15 -0.2556 -0.9819 3187865 PK04_103167 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I10 compound treatment 480636.0 36700.0 0.22 334890.0 -156000.0 -0.89 -0.4732 -0.5178 3070600 PK04_103168 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I11 compound treatment 388746.0 -55200.0 -0.33 429247.0 -61700.0 -0.35 -0.4804 -0.9995 3187866 PK04_103169 COCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I12 compound treatment 149213.0 -295000.0 -1.75 145850.0 -345000.0 -1.96 -2.628 -0.9984 3187978 PK04_103170 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I13 compound treatment 417179.0 -26800.0 -0.16 379268.0 -112000.0 -0.64 -0.5618 -0.858 3070601 PK04_103171 CCCCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I14 compound treatment 61549.0 -382000.0 -2.28 64477.0 -426000.0 -2.43 -3.3242 -0.9995 3187979 PK04_103172 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I15 compound treatment 297873.0 -146000.0 -0.87 333675.0 -157000.0 -0.89 -1.2472 -0.9999 3070602 PK04_103173 CC(C)C(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I16 compound treatment 58503.0 -385000.0 -2.29 42493.0 -448000.0 -2.55 -3.4254 -0.9986 3187980 PK04_103174 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I17 compound treatment 386292.0 -57700.0 -0.34 412581.0 -78300.0 -0.45 -0.5578 -0.9917 3070603 PK04_103175 COCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I18 compound treatment 253301.0 -191000.0 -1.13 340581.0 -150000.0 -0.86 -1.407 -0.9903 3187981 PK04_103176 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I19 compound treatment 53743.0 -390000.0 -2.32 78272.0 -413000.0 -2.35 -3.3015 -1.0 3070604 PK04_103177 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I20 compound treatment 137864.0 -306000.0 -1.82 94855.0 -396000.0 -2.25 -2.8809 -0.9945 3187982 PK04_103178 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I21 mock treatment 488949.0 45000.0 0.27 228408.0 -263000.0 -1.49 -0.8664 -0.5712 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I22 mock treatment 448673.0 4700.0 0.03 357042.0 -134000.0 -0.76 -0.5186 -0.6807 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I23 compound treatment 51543.0 -392000.0 -2.34 61770.0 -429000.0 -2.44 -3.3772 -0.9998 3187983 PK04_103179 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 I24 compound treatment 172636.0 -271000.0 -1.61 201633.0 -289000.0 -1.65 -2.3052 -1.0 3070605 PK04_103180 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J01 compound treatment 45770.0 -398000.0 -2.37 64749.0 -426000.0 -2.42 -3.3895 -0.9999 3187984 PK04_103181 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J02 compound treatment 479899.0 35900.0 0.21 454985.0 -35900.0 -0.2 0.0067 0.0225 3187985 PK04_103182 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J03 compound treatment 173399.0 -271000.0 -1.61 109882.0 -381000.0 -2.17 -2.6709 -0.9893 3070606 PK04_103183 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J04 compound treatment 333886.0 -110000.0 -0.66 476830.0 -14100.0 -0.08 -0.52 -0.7878 3187986 PK04_103184 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J05 mock treatment 509195.0 65200.0 0.39 484377.0 -6550.0 -0.04 0.2481 0.6363 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J06 mock treatment 282759.0 -161000.0 -0.96 270952.0 -220000.0 -1.25 -1.563 -0.9914 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J07 compound treatment 67442.0 -377000.0 -2.24 62694.0 -428000.0 -2.44 -3.3065 -0.9991 3187987 PK04_103185 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J08 compound treatment 65430.0 -379000.0 -2.25 67158.0 -424000.0 -2.41 -3.2971 -0.9994 3070607 PK04_103186 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J09 compound treatment 511181.0 67200.0 0.4 476984.0 -13900.0 -0.08 0.2268 0.5561 3187988 PK04_103187 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J10 compound treatment 286108.0 -158000.0 -0.94 298966.0 -192000.0 -1.09 -1.4362 -0.9972 3070608 PK04_103188 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J11 compound treatment 251627.0 -192000.0 -1.14 360806.0 -130000.0 -0.74 -1.3327 -0.9777 3187989 PK04_103189 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J12 compound treatment 166708.0 -277000.0 -1.65 470588.0 -20300.0 -0.12 -1.2486 -0.7548 3070609 PK04_103190 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J13 compound treatment 209465.0 -235000.0 -1.4 317160.0 -174000.0 -0.99 -1.6856 -0.9857 3187990 PK04_103191 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J14 compound treatment 179316.0 -265000.0 -1.58 164953.0 -326000.0 -1.85 -2.4245 -0.9967 3187991 PK04_103192 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J15 compound treatment 62081.0 -382000.0 -2.27 61103.0 -430000.0 -2.44 -3.3355 -0.9993 3070610 PK04_103193 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J16 compound treatment 129090.0 -315000.0 -1.87 120265.0 -371000.0 -2.11 -2.8156 -0.9983 3187992 PK04_103194 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J17 compound treatment 32468.0 -412000.0 -2.45 79444.0 -411000.0 -2.34 -3.3864 -0.9997 3070654 PK04_103195 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J18 compound treatment 450165.0 6190.0 0.04 500378.0 9450.0 0.05 0.0641 0.9831 3187993 PK04_103196 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J19 compound treatment 215448.0 -229000.0 -1.36 96940.0 -394000.0 -2.24 -2.546 -0.9714 3070655 PK04_103197 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J20 compound treatment 99539.0 -344000.0 -2.05 109840.0 -381000.0 -2.17 -2.9819 -0.9996 3187994 PK04_103198 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J21 mock treatment 493905.0 49900.0 0.3 528724.0 37800.0 0.21 0.3621 0.9873 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J22 mock treatment 358674.0 -85300.0 -0.51 356562.0 -134000.0 -0.76 -0.8993 -0.9803 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J23 compound treatment 53717.0 -390000.0 -2.32 59514.0 -431000.0 -2.45 -3.3771 -0.9996 3187995 PK04_103199 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 J24 compound treatment 482833.0 38900.0 0.23 493770.0 2840.0 0.02 0.175 0.7546 3070656 PK04_103200 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K01 compound treatment 468371.0 24400.0 0.15 400738.0 -90200.0 -0.51 -0.26 -0.4877 3187996 PK04_103201 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K02 compound treatment 376857.0 -67100.0 -0.4 342109.0 -149000.0 -0.85 -0.8809 -0.9413 3187997 PK04_103202 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K03 compound treatment 369377.0 -74600.0 -0.44 304346.0 -187000.0 -1.06 -1.0642 -0.9252 3070657 PK04_103203 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K04 compound treatment 184069.0 -260000.0 -1.55 164629.0 -326000.0 -1.86 -2.4058 -0.9959 3187998 PK04_103204 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K05 compound treatment 489813.0 45800.0 0.27 459742.0 -31200.0 -0.18 0.0675 0.2074 3070658 PK04_103205 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K06 compound treatment 329704.0 -114000.0 -0.68 300473.0 -190000.0 -1.08 -1.2467 -0.9749 3187999 PK04_103206 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K07 mock treatment 557079.0 113000.0 0.67 520934.0 30000.0 0.17 0.5966 0.8592 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K08 mock treatment 566040.0 122000.0 0.73 571571.0 80600.0 0.46 0.838 0.9754 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K09 compound treatment 441890.0 -2080.0 -0.01 518705.0 27800.0 0.16 0.1029 0.6497 3188000 PK04_103207 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K10 compound treatment 241474.0 -202000.0 -1.21 247980.0 -243000.0 -1.38 -1.8291 -0.9977 3070659 PK04_103208 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K11 compound treatment 80019.0 -364000.0 -2.17 145826.0 -345000.0 -1.96 -2.9193 -0.9988 3188108 PK04_103209 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K12 compound treatment 59491.0 -384000.0 -2.29 65753.0 -425000.0 -2.42 -3.3277 -0.9996 3188109 PK04_103210 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K13 compound treatment 143298.0 -301000.0 -1.79 85506.0 -405000.0 -2.31 -2.8956 -0.9922 3070660 PK04_103211 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K14 compound treatment 436055.0 -7920.0 -0.05 352277.0 -139000.0 -0.79 -0.5909 -0.748 3188110 PK04_103212 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K15 mock treatment 362620.0 -81400.0 -0.48 461078.0 -29900.0 -0.17 -0.4624 -0.9013 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K16 mock treatment 497749.0 53800.0 0.32 530271.0 39300.0 0.22 0.3845 0.9847 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K17 compound treatment 189807.0 -254000.0 -1.51 253365.0 -238000.0 -1.35 -2.0249 -0.9984 3070661 PK04_103213 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K18 compound treatment 317509.0 -126000.0 -0.75 435104.0 -55800.0 -0.32 -0.7567 -0.9263 3188111 PK04_103214 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K19 compound treatment 59928.0 -384000.0 -2.29 62034.0 -429000.0 -2.44 -3.3408 -0.9995 3188112 PK04_103215 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K20 compound treatment 427877.0 -16100.0 -0.1 420674.0 -70300.0 -0.4 -0.3502 -0.8525 3070662 PK04_103216 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K21 compound treatment 50484.0 -393000.0 -2.34 55009.0 -436000.0 -2.48 -3.4088 -0.9996 3188113 PK04_103217 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K22 compound treatment 445301.0 1330.0 0.01 555486.0 64600.0 0.37 0.2652 0.7222 3188114 PK04_103218 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K23 mock treatment 488666.0 44700.0 0.27 597477.0 107000.0 0.61 0.6165 0.9317 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 K24 mock treatment 506385.0 62400.0 0.37 600586.0 110000.0 0.62 0.7036 0.9694 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L01 compound treatment 300458.0 -144000.0 -0.85 325042.0 -166000.0 -0.94 -1.271 -0.9988 3070663 PK04_103219 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L02 compound treatment 429442.0 -14500.0 -0.09 476112.0 -14800.0 -0.08 -0.1207 -0.9999 3188115 PK04_103220 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L03 compound treatment 69307.0 -375000.0 -2.23 60813.0 -430000.0 -2.45 -3.3063 -0.9989 3070664 PK04_103221 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L04 compound treatment 454187.0 10200.0 0.06 408308.0 -82600.0 -0.47 -0.2892 -0.6105 3188116 PK04_103222 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L05 compound treatment 81835.0 -362000.0 -2.16 72503.0 -418000.0 -2.38 -3.2065 -0.9988 3070665 PK04_103223 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L06 compound treatment 73769.0 -370000.0 -2.2 73424.0 -418000.0 -2.37 -3.2368 -0.9993 3188117 PK04_103224 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L07 mock treatment 516392.0 72400.0 0.43 612374.0 121000.0 0.69 0.7931 0.9742 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L08 mock treatment 300876.0 -143000.0 -0.85 358991.0 -132000.0 -0.75 -1.1327 -0.998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L09 compound treatment 326371.0 -118000.0 -0.7 164202.0 -327000.0 -1.86 -1.8087 -0.911 3188118 PK04_103225 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L10 compound treatment 341851.0 -102000.0 -0.61 201264.0 -290000.0 -1.65 -1.5945 -0.9082 3188119 PK04_103226 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L11 compound treatment 63318.0 -381000.0 -2.27 49753.0 -441000.0 -2.51 -3.3759 -0.9987 3070666 PK04_103227 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L12 compound treatment 66297.0 -378000.0 -2.25 69515.0 -421000.0 -2.4 -3.2839 -0.9995 3188120 PK04_103228 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L13 compound treatment 452612.0 8640.0 0.05 422601.0 -68300.0 -0.39 -0.2384 -0.6082 3188121 PK04_103229 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L14 compound treatment 61357.0 -383000.0 -2.28 68050.0 -423000.0 -2.4 -3.3106 -0.9996 3188122 PK04_103230 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L15 mock treatment 457875.0 13900.0 0.08 566720.0 75800.0 0.43 0.3633 0.8278 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L16 mock treatment 292685.0 -151000.0 -0.9 345549.0 -145000.0 -0.83 -1.2213 -0.9991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L17 compound treatment 290260.0 -154000.0 -0.91 389162.0 -102000.0 -0.58 -1.0561 -0.9756 3070709 PK04_103231 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L18 compound treatment 295731.0 -148000.0 -0.88 290119.0 -201000.0 -1.14 -1.4313 -0.9919 3188123 PK04_103232 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L19 compound treatment 443160.0 -810.0 0.0 443895.0 -47000.0 -0.27 -0.1925 -0.7197 3070710 PK04_103233 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L20 compound treatment 64629.0 -379000.0 -2.26 70654.0 -420000.0 -2.39 -3.2864 -0.9996 3188124 PK04_103234 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L21 compound treatment 361671.0 -82300.0 -0.49 417971.0 -73000.0 -0.41 -0.6397 -0.9966 3070711 PK04_103235 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L22 compound treatment 382347.0 -61600.0 -0.37 477060.0 -13900.0 -0.08 -0.3151 -0.84 3188125 PK04_103236 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L23 mock treatment 513577.0 69600.0 0.41 552559.0 61600.0 0.35 0.5407 0.9965 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 L24 mock treatment 488372.0 44400.0 0.26 534592.0 43700.0 0.25 0.3624 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M01 compound treatment 164391.0 -280000.0 -1.66 210297.0 -281000.0 -1.6 -2.305 -0.9998 3070712 PK04_103237 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M02 compound treatment 441071.0 -2900.0 -0.02 452635.0 -38300.0 -0.22 -0.1662 -0.7607 3188126 PK04_103238 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M03 compound treatment 108549.0 -335000.0 -2.0 66493.0 -424000.0 -2.41 -3.1183 -0.9955 3070713 PK04_103239 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M04 compound treatment 377855.0 -66100.0 -0.39 408452.0 -82500.0 -0.47 -0.6099 -0.9962 3188127 PK04_103240 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M05 compound treatment 301701.0 -142000.0 -0.85 224353.0 -267000.0 -1.52 -1.6707 -0.9621 3188128 PK04_103241 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M06 compound treatment 419570.0 -24400.0 -0.15 410787.0 -80100.0 -0.46 -0.425 -0.8884 3070714 PK04_103242 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M07 compound treatment 344567.0 -99400.0 -0.59 354484.0 -136000.0 -0.78 -0.967 -0.991 3188237 PK04_103243 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M08 compound treatment 338453.0 -106000.0 -0.63 353140.0 -138000.0 -0.78 -0.9981 -0.994 3070715 PK04_103244 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M09 mock treatment 572971.0 129000.0 0.77 578125.0 87200.0 0.5 0.8935 0.9776 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M10 mock treatment 595867.0 152000.0 0.9 615514.0 125000.0 0.71 1.1402 0.9927 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M11 compound treatment 64233.0 -380000.0 -2.26 70694.0 -420000.0 -2.39 -3.2879 -0.9996 3188238 PK04_103245 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M12 compound treatment 68241.0 -376000.0 -2.24 64912.0 -426000.0 -2.42 -3.2943 -0.9992 3188239 PK04_103246 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M13 mock treatment 366022.0 -77900.0 -0.46 523046.0 32100.0 0.18 -0.1989 -0.3989 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M14 mock treatment 527267.0 83300.0 0.5 595596.0 105000.0 0.6 0.7714 0.9959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M15 compound treatment 55025.0 -389000.0 -2.31 46333.0 -445000.0 -2.53 -3.4246 -0.999 3070716 PK04_103247 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M16 compound treatment 228112.0 -216000.0 -1.28 265791.0 -225000.0 -1.28 -1.8137 -1.0 3188240 PK04_103248 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M17 compound treatment 88634.0 -355000.0 -2.11 133852.0 -357000.0 -2.03 -2.9312 -0.9998 3070717 PK04_103249 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M18 compound treatment 65758.0 -378000.0 -2.25 65870.0 -425000.0 -2.42 -3.3009 -0.9994 3188241 PK04_103250 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M19 compound treatment 342572.0 -101000.0 -0.6 458794.0 -32100.0 -0.18 -0.5559 -0.8817 3188242 PK04_103251 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M20 compound treatment 96007.0 -348000.0 -2.07 56668.0 -434000.0 -2.47 -3.2106 -0.9962 3070718 PK04_103252 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M21 compound treatment 163070.0 -281000.0 -1.67 322049.0 -169000.0 -0.96 -1.8612 -0.9654 3188243 PK04_103253 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M22 compound treatment 212486.0 -231000.0 -1.38 100688.0 -390000.0 -2.22 -2.5434 -0.9737 3188244 PK04_103254 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M23 compound treatment 514274.0 70300.0 0.42 586896.0 96000.0 0.55 0.6817 0.9914 3188245 PK04_103255 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 M24 compound treatment 269808.0 -174000.0 -1.04 353449.0 -137000.0 -0.78 -1.2858 -0.9903 3070768 PK04_103256 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N01 compound treatment 528553.0 84600.0 0.5 558158.0 67200.0 0.38 0.6263 0.9908 3188246 PK04_103257 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N02 compound treatment 535102.0 91100.0 0.54 522191.0 31300.0 0.18 0.5092 0.8922 3188247 PK04_103258 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N03 compound treatment 517274.0 73300.0 0.44 582431.0 91500.0 0.52 0.6764 0.9962 3070772 PK04_103259 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N04 compound treatment 400738.0 -43200.0 -0.26 402252.0 -88700.0 -0.5 -0.5385 -0.9512 3188248 PK04_103260 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N05 compound treatment 524672.0 80700.0 0.48 620141.0 129000.0 0.73 0.8592 0.9788 3188249 PK04_103261 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N06 compound treatment 143542.0 -300000.0 -1.79 138754.0 -352000.0 -2.0 -2.6804 -0.9984 3188250 PK04_103262 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N07 compound treatment 555867.0 112000.0 0.67 561203.0 70300.0 0.4 0.7535 0.9702 3070060 PK04_103263 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N08 compound treatment 284002.0 -160000.0 -0.95 294426.0 -197000.0 -1.12 -1.4634 -0.9968 3188251 PK04_103264 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N09 mock treatment 586929.0 143000.0 0.85 563487.0 72600.0 0.41 0.8934 0.9448 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N10 mock treatment 428390.0 -15600.0 -0.09 419899.0 -71000.0 -0.4 -0.3512 -0.8474 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N11 compound treatment 491675.0 47700.0 0.28 577752.0 86800.0 0.49 0.5499 0.9655 3070061 PK04_103265 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N12 compound treatment 317546.0 -126000.0 -0.75 422503.0 -68400.0 -0.39 -0.8072 -0.9529 3188252 PK04_103266 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N13 mock treatment 573032.0 129000.0 0.77 568532.0 77600.0 0.44 0.8552 0.9654 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N14 mock treatment 446028.0 2060.0 0.01 452948.0 -38000.0 -0.22 -0.1441 -0.6659 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N15 compound treatment 461324.0 17400.0 0.1 465502.0 -25400.0 -0.14 -0.0292 -0.1645 3070062 PK04_103267 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N16 compound treatment 526989.0 83000.0 0.49 554741.0 63800.0 0.36 0.606 0.9885 3188253 PK04_103268 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N17 compound treatment 329975.0 -114000.0 -0.68 532208.0 41300.0 0.23 -0.3137 -0.437 3070063 PK04_103269 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N18 compound treatment 464512.0 20500.0 0.12 494635.0 3700.0 0.02 0.1013 0.8169 3188254 PK04_103270 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N19 compound treatment 489397.0 45400.0 0.27 617307.0 126000.0 0.72 0.6993 0.9108 3070064 PK04_103271 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N20 compound treatment 111286.0 -333000.0 -1.98 157862.0 -333000.0 -1.89 -2.7393 -0.9998 3188255 PK04_103272 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N21 compound treatment 353571.0 -90400.0 -0.54 516737.0 25800.0 0.15 -0.2767 -0.4961 3070065 PK04_103273 CCCCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N22 compound treatment 177953.0 -266000.0 -1.58 171073.0 -320000.0 -1.82 -2.4057 -0.9976 3188256 PK04_103274 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N23 compound treatment 478843.0 34900.0 0.21 526127.0 35200.0 0.2 0.2883 0.9998 3070066 PK04_103275 CC(C)C(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 N24 compound treatment 500442.0 56500.0 0.34 542458.0 51500.0 0.29 0.4448 0.9977 3188257 PK04_103276 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O01 compound treatment 505858.0 61900.0 0.37 302522.0 -188000.0 -1.07 -0.4972 -0.4388 3188258 PK04_103277 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O02 compound treatment 355253.0 -88700.0 -0.53 354003.0 -137000.0 -0.78 -0.924 -0.9821 3070067 PK04_103278 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O03 compound treatment 491031.0 47100.0 0.28 516545.0 25600.0 0.15 0.301 0.9536 3188259 PK04_103279 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O04 compound treatment 314512.0 -129000.0 -0.77 310504.0 -180000.0 -1.03 -1.2703 -0.99 3188369 PK04_103280 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O05 compound treatment 544287.0 100000.0 0.6 397567.0 -93400.0 -0.53 0.0467 0.0585 3070068 PK04_103281 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O06 compound treatment 399749.0 -44200.0 -0.26 348056.0 -143000.0 -0.81 -0.7606 -0.8906 3188370 PK04_103282 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O07 compound treatment 554938.0 111000.0 0.66 548909.0 58000.0 0.33 0.7001 0.9485 3070069 PK04_103283 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O08 compound treatment 115048.0 -329000.0 -1.96 92822.0 -398000.0 -2.26 -2.9851 -0.9974 3188371 PK04_103284 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O09 compound treatment 505709.0 61700.0 0.37 475526.0 -15400.0 -0.09 0.1979 0.5238 3188372 PK04_103285 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O10 compound treatment 139443.0 -305000.0 -1.81 155532.0 -335000.0 -1.91 -2.6302 -0.9997 3070070 PK04_103286 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O11 mock treatment 611943.0 168000.0 1.0 522824.0 31900.0 0.18 0.8351 0.822 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O12 mock treatment 530487.0 86500.0 0.51 554366.0 63400.0 0.36 0.6192 0.9849 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O13 compound treatment 579716.0 136000.0 0.81 583443.0 92500.0 0.53 0.9433 0.9784 3188373 PK04_103287 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O14 compound treatment 70751.0 -373000.0 -2.22 73122.0 -418000.0 -2.38 -3.2507 -0.9994 3188374 PK04_103288 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O15 compound treatment 114789.0 -329000.0 -1.96 120093.0 -371000.0 -2.11 -2.8765 -0.9993 3070071 PK04_103289 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O16 compound treatment 61768.0 -382000.0 -2.27 81121.0 -410000.0 -2.33 -3.2563 -0.9999 3188375 PK04_103290 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O17 compound treatment 80927.0 -363000.0 -2.16 114429.0 -377000.0 -2.14 -3.0418 -1.0 3070072 PK04_103291 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O18 compound treatment 175749.0 -268000.0 -1.6 218966.0 -272000.0 -1.55 -2.2224 -0.9999 3188376 PK04_103292 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O19 compound treatment 367804.0 -76200.0 -0.45 319004.0 -172000.0 -0.98 -1.0119 -0.9389 3188377 PK04_103293 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O20 compound treatment 133101.0 -311000.0 -1.85 74334.0 -417000.0 -2.37 -2.9834 -0.9925 3070073 PK04_103294 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O21 compound treatment 331247.0 -113000.0 -0.67 369031.0 -122000.0 -0.69 -0.9645 -0.9999 3188378 PK04_103295 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O22 compound treatment 187108.0 -257000.0 -1.53 201145.0 -290000.0 -1.65 -2.2462 -0.9993 3188379 PK04_103296 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O23 compound treatment 395077.0 -48900.0 -0.29 497008.0 6080.0 0.03 -0.1813 -0.6188 3070074 PK04_103297 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 O24 compound treatment 418719.0 -25300.0 -0.15 439799.0 -51100.0 -0.29 -0.3119 -0.9528 3188380 PK04_103298 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P01 compound treatment 524446.0 80500.0 0.48 450985.0 -39900.0 -0.23 0.178 0.3359 3070075 PK04_103299 COCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P02 compound treatment 416030.0 -27900.0 -0.17 437801.0 -53100.0 -0.3 -0.3312 -0.9604 3188381 PK04_103300 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P03 compound treatment 292673.0 -151000.0 -0.9 312946.0 -178000.0 -1.01 -1.3524 -0.9983 3188382 PK04_103301 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P04 compound treatment 357799.0 -86200.0 -0.51 343748.0 -147000.0 -0.84 -0.9545 -0.9724 3070118 PK04_103302 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P05 compound treatment 383705.0 -60300.0 -0.36 399966.0 -91000.0 -0.52 -0.6194 -0.984 3188383 PK04_103303 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P06 compound treatment 465616.0 21600.0 0.13 346732.0 -144000.0 -0.82 -0.4888 -0.5888 3070119 PK04_103304 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P07 compound treatment 486994.0 43000.0 0.26 471998.0 -18900.0 -0.11 0.1049 0.3777 3188384 PK04_103305 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P08 compound treatment 65036.0 -379000.0 -2.26 60954.0 -430000.0 -2.45 -3.3237 -0.9992 3188385 PK04_103306 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P09 compound treatment 358422.0 -85500.0 -0.51 280407.0 -211000.0 -1.2 -1.2066 -0.9274 3070120 PK04_103307 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P10 compound treatment 172669.0 -271000.0 -1.61 256489.0 -234000.0 -1.33 -2.0844 -0.9955 3188386 PK04_103308 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P11 mock treatment 553219.0 109000.0 0.65 610664.0 120000.0 0.68 0.9412 0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P12 mock treatment 541452.0 97500.0 0.58 462420.0 -28500.0 -0.16 0.2956 0.4907 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P13 compound treatment 470541.0 26600.0 0.16 465814.0 -25100.0 -0.14 0.0108 0.0508 3070121 PK04_103309 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P14 compound treatment 581850.0 138000.0 0.82 577074.0 86100.0 0.49 0.9266 0.9696 3188387 PK04_103310 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P15 compound treatment 578989.0 135000.0 0.8 637844.0 147000.0 0.84 1.159 0.9998 3188388 PK04_103311 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P16 compound treatment 624700.0 181000.0 1.08 502886.0 12000.0 0.07 0.8086 0.7503 3070122 PK04_103312 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P17 compound treatment 181878.0 -262000.0 -1.56 183703.0 -307000.0 -1.75 -2.3384 -0.9984 3188389 PK04_103313 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P18 compound treatment 363439.0 -80500.0 -0.48 338206.0 -153000.0 -0.87 -0.953 -0.9607 3188390 PK04_103314 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P19 compound treatment 456815.0 12800.0 0.08 393458.0 -97500.0 -0.55 -0.3379 -0.6039 3070123 PK04_103315 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P20 compound treatment 584186.0 140000.0 0.83 585066.0 94100.0 0.54 0.9686 0.977 3188503 PK04_103316 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P21 compound treatment 545725.0 102000.0 0.61 468391.0 -22500.0 -0.13 0.3376 0.5454 3188504 PK04_103317 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P22 compound treatment 414294.0 -29700.0 -0.18 547528.0 56600.0 0.32 0.1027 0.2797 3070124 PK04_103318 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P23 compound treatment 52781.0 -391000.0 -2.33 59753.0 -431000.0 -2.45 -3.3801 -0.9997 3188505 PK04_103319 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2103 P24 compound treatment 75290.0 -369000.0 -2.19 77090.0 -414000.0 -2.35 -3.2156 -0.9994 3188506 PK04_103320 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A01 compound treatment 504883.0 75500.0 0.45 505225.0 48600.0 0.28 0.5133 0.9728 3220649 PK04_107001 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A02 compound treatment 75915.0 -353000.0 -2.1 81624.0 -375000.0 -2.13 -2.9953 -1.0 3188507 PK04_107002 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A03 compound treatment 491465.0 62100.0 0.37 573772.0 117000.0 0.67 0.7324 0.9613 3220651 PK04_107003 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A04 compound treatment 296871.0 -133000.0 -0.79 317528.0 -139000.0 -0.79 -1.1169 -1.0 3070126 PK04_107004 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A05 compound treatment 518197.0 88800.0 0.53 559336.0 103000.0 0.58 0.7869 0.9987 3220653 PK04_107005 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A06 compound treatment 143649.0 -286000.0 -1.7 220618.0 -236000.0 -1.34 -2.1514 -0.9931 3070127 PK04_107006 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A07 compound treatment 452930.0 23500.0 0.14 417176.0 -39400.0 -0.22 -0.0594 -0.2248 3220655 PK04_107007 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A08 compound treatment 75423.0 -354000.0 -2.11 76695.0 -380000.0 -2.16 -3.0172 -0.9999 3070128 PK04_107008 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A09 compound treatment 408441.0 -20900.0 -0.12 534817.0 78200.0 0.44 0.2264 0.4901 3220657 PK04_107009 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A10 compound treatment 152703.0 -277000.0 -1.65 184248.0 -272000.0 -1.55 -2.2595 -0.9995 3070129 PK04_107010 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A11 compound treatment 456458.0 27100.0 0.16 440901.0 -15700.0 -0.09 0.0508 0.2759 3220659 PK04_107011 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A12 compound treatment 23694.0 -406000.0 -2.41 64625.0 -392000.0 -2.23 -3.2834 -0.9992 3188513 PK04_107012 CCCCCCc1nc(CCCc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)cc4CO[Si](C(C)C)(C(C)C)c41 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A13 mock treatment 492682.0 63300.0 0.38 511181.0 54600.0 0.31 0.4859 0.9954 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A14 mock treatment 252536.0 -177000.0 -1.05 525680.0 69100.0 0.39 -0.4664 -0.4152 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A15 compound treatment 198582.0 -231000.0 -1.37 175770.0 -281000.0 -1.6 -2.1005 -0.9972 3220661 PK04_107013 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A16 compound treatment 37781.0 -392000.0 -2.33 57309.0 -399000.0 -2.27 -3.2536 -0.9999 3188514 PK04_107014 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A17 compound treatment 492798.0 63400.0 0.38 201430.0 -255000.0 -1.45 -0.7592 -0.5064 3220663 PK04_107015 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3ccccc3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A18 compound treatment 106569.0 -323000.0 -1.92 87899.0 -369000.0 -2.1 -2.8411 -0.999 3070178 PK04_107016 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A19 compound treatment 564384.0 135000.0 0.8 436087.0 -20500.0 -0.12 0.4856 0.5982 3220665 PK04_107017 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A20 compound treatment 151897.0 -277000.0 -1.65 184183.0 -272000.0 -1.55 -2.2632 -0.9995 3070179 PK04_107018 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A21 compound treatment 207414.0 -222000.0 -1.32 509439.0 52800.0 0.3 -0.7216 -0.5326 3220667 PK04_107019 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A22 compound treatment 434463.0 5080.0 0.03 522449.0 65900.0 0.37 0.2862 0.7617 3070180 PK04_107020 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A23 compound treatment 398871.0 -30500.0 -0.18 536087.0 79500.0 0.45 0.1912 0.3925 3220669 PK04_107021 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 A24 compound treatment 445978.0 16600.0 0.1 400599.0 -56000.0 -0.32 -0.1553 -0.466 3070181 PK04_107022 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B01 compound treatment 416817.0 -12600.0 -0.07 474230.0 17600.0 0.1 0.018 0.144 3188518 PK04_107023 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B02 compound treatment 291852.0 -138000.0 -0.82 312471.0 -144000.0 -0.82 -1.1583 -1.0 3188519 PK04_107024 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B03 compound treatment 491316.0 61900.0 0.37 458770.0 2180.0 0.01 0.2694 0.7304 3070182 PK04_107025 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B04 compound treatment 508033.0 78600.0 0.47 322004.0 -135000.0 -0.77 -0.2102 -0.2343 3188520 PK04_107026 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B05 compound treatment 289022.0 -140000.0 -0.84 479404.0 22800.0 0.13 -0.499 -0.5902 3188521 PK04_107027 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B06 compound treatment 397975.0 -31400.0 -0.19 349184.0 -107000.0 -0.61 -0.5641 -0.8831 3070183 PK04_107028 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B07 compound treatment 250357.0 -179000.0 -1.07 346390.0 -110000.0 -0.63 -1.1966 -0.968 3188640 PK04_107029 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B08 compound treatment 309811.0 -120000.0 -0.71 546421.0 89800.0 0.51 -0.142 -0.1621 3188641 PK04_107030 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B09 compound treatment 265211.0 -164000.0 -0.98 458957.0 2360.0 0.01 -0.6814 -0.6973 3070184 PK04_107031 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B10 compound treatment 288099.0 -141000.0 -0.84 346874.0 -110000.0 -0.62 -1.0358 -0.9892 3188642 PK04_107032 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B11 compound treatment 559609.0 130000.0 0.78 496365.0 39800.0 0.23 0.7079 0.8769 3070185 PK04_107033 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B12 compound treatment 505453.0 76100.0 0.45 471708.0 15100.0 0.09 0.3809 0.8266 3188643 PK04_107034 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B13 mock treatment 544479.0 115000.0 0.68 230304.0 -226000.0 -1.29 -0.4256 -0.2919 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B14 mock treatment 464320.0 34900.0 0.21 516573.0 60000.0 0.34 0.3882 0.9718 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B15 compound treatment 529486.0 100000.0 0.6 555020.0 98400.0 0.56 0.817 0.9995 3188644 PK04_107035 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B16 compound treatment 503236.0 73800.0 0.44 469883.0 13300.0 0.08 0.3642 0.8167 3070186 PK04_107036 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B17 compound treatment 535871.0 106000.0 0.63 364704.0 -91900.0 -0.52 0.0786 0.0957 3188645 PK04_107037 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B18 compound treatment 577379.0 148000.0 0.88 498417.0 41800.0 0.24 0.791 0.867 3188646 PK04_107038 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B19 compound treatment 513501.0 84100.0 0.5 444961.0 -11600.0 -0.07 0.3072 0.6084 3070187 PK04_107039 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B20 compound treatment 443318.0 13900.0 0.08 157579.0 -299000.0 -1.7 -1.1438 -0.6718 3188647 PK04_107040 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B21 compound treatment 518719.0 89300.0 0.53 153963.0 -303000.0 -1.72 -0.841 -0.4669 3188648 PK04_107041 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B22 compound treatment 706854.0 277000.0 1.65 318365.0 -138000.0 -0.79 0.6118 0.3345 3070188 PK04_107042 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B23 compound treatment 818917.0 390000.0 2.32 486410.0 29800.0 0.17 1.7592 0.7568 3188649 PK04_107043 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 B24 compound treatment 667258.0 238000.0 1.42 631221.0 175000.0 0.99 1.7032 0.985 3188650 PK04_107044 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C01 compound treatment 459719.0 30300.0 0.18 476680.0 20100.0 0.11 0.2084 0.9756 3414054 PK04_107045 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C02 compound treatment 343700.0 -85700.0 -0.51 453535.0 -3060.0 -0.02 -0.3729 -0.7308 3188651 PK04_107046 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C03 compound treatment 485200.0 55800.0 0.33 602958.0 146000.0 0.83 0.8234 0.9188 3414055 PK04_107047 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C04 compound treatment 427707.0 -1680.0 -0.01 445337.0 -11300.0 -0.06 -0.0523 -0.8078 3070235 PK04_107048 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C05 compound treatment 445260.0 15900.0 0.09 490947.0 34400.0 0.2 0.2049 0.9444 3414056 PK04_107049 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C06 compound treatment 445567.0 16200.0 0.1 375050.0 -81500.0 -0.46 -0.2598 -0.5486 3070236 PK04_107050 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C07 compound treatment 468303.0 38900.0 0.23 487314.0 30700.0 0.17 0.2873 0.9903 3414057 PK04_107051 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C08 compound treatment 298286.0 -131000.0 -0.78 322226.0 -134000.0 -0.76 -1.092 -0.9999 3188655 PK04_107052 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C09 compound treatment 400475.0 -28900.0 -0.17 485973.0 29400.0 0.17 -0.0035 -0.0147 3220705 PK04_107053 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C10 compound treatment 370375.0 -59000.0 -0.35 296499.0 -160000.0 -0.91 -0.8921 -0.9142 3188656 PK04_107054 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C11 mock treatment 474245.0 44900.0 0.27 479150.0 22600.0 0.13 0.2795 0.9436 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C12 mock treatment 408640.0 -20700.0 -0.12 524584.0 68000.0 0.39 0.1861 0.4585 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C13 compound treatment 473449.0 44100.0 0.26 523357.0 66800.0 0.38 0.4539 0.9837 3220708 PK04_107055 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C14 compound treatment 380494.0 -48900.0 -0.29 414845.0 -41700.0 -0.24 -0.3736 -0.9949 3188772 PK04_107056 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C15 mock treatment 240943.0 -188000.0 -1.12 280000.0 -177000.0 -1.0 -1.5031 -0.9985 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C16 mock treatment 417211.0 -12200.0 -0.07 505834.0 49200.0 0.28 0.1468 0.5074 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C17 compound treatment 443448.0 14100.0 0.08 505978.0 49400.0 0.28 0.2578 0.8796 3220711 PK04_107057 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C18 compound treatment 266179.0 -163000.0 -0.97 188371.0 -268000.0 -1.53 -1.7654 -0.9763 3070242 PK04_107058 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C19 compound treatment 424180.0 -5210.0 -0.03 456214.0 -379.0 0.0 -0.0234 -0.7545 3220713 PK04_107059 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C20 compound treatment 207162.0 -222000.0 -1.32 313764.0 -143000.0 -0.81 -1.5095 -0.9726 3070245 PK04_107060 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C21 compound treatment 504276.0 74900.0 0.45 479640.0 23000.0 0.13 0.4078 0.8779 3220715 PK04_107061 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C22 compound treatment 210684.0 -219000.0 -1.3 551814.0 95200.0 0.54 -0.5375 -0.3813 3070527 PK04_107062 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C23 compound treatment 157157.0 -272000.0 -1.62 512791.0 56200.0 0.32 -0.9196 -0.5569 3220717 PK04_107063 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 C24 compound treatment 367364.0 -62000.0 -0.37 442140.0 -14500.0 -0.08 -0.3191 -0.8439 3070530 PK04_107064 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D01 compound treatment 435751.0 6360.0 0.04 538671.0 82100.0 0.47 0.3568 0.762 3188777 PK04_107065 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D02 compound treatment 469290.0 39900.0 0.24 367729.0 -88900.0 -0.51 -0.1894 -0.3392 3188778 PK04_107066 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D03 compound treatment 430073.0 686.0 0.0 480386.0 23800.0 0.14 0.0986 0.7281 3070575 PK04_107067 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D04 compound treatment 313735.0 -116000.0 -0.69 578403.0 122000.0 0.69 0.0031 0.0032 3188779 PK04_107068 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D05 compound treatment 237405.0 -192000.0 -1.14 342575.0 -114000.0 -0.65 -1.2664 -0.964 3188780 PK04_107069 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D06 compound treatment 303156.0 -126000.0 -0.75 489504.0 32900.0 0.19 -0.3989 -0.5152 3070579 PK04_107070 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D07 compound treatment 531680.0 102000.0 0.61 232747.0 -224000.0 -1.27 -0.4696 -0.3328 3188781 PK04_107071 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D08 compound treatment 501407.0 72000.0 0.43 486960.0 30400.0 0.17 0.4252 0.9201 3188782 PK04_107072 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D09 compound treatment 454586.0 25200.0 0.15 457478.0 885.0 0.01 0.1096 0.7304 3188783 PK04_107073 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D10 compound treatment 447319.0 17900.0 0.11 304472.0 -152000.0 -0.87 -0.5362 -0.6152 3070632 PK04_107074 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D11 mock treatment 227165.0 -202000.0 -1.2 281021.0 -176000.0 -1.0 -1.557 -0.9957 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D12 mock treatment 432112.0 2720.0 0.02 477488.0 20900.0 0.12 0.0955 0.7962 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D13 compound treatment 441176.0 11800.0 0.07 166515.0 -290000.0 -1.65 -1.1168 -0.6764 3188784 PK04_107075 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D14 compound treatment 311531.0 -118000.0 -0.7 410992.0 -45600.0 -0.26 -0.6793 -0.9084 3188785 PK04_107076 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D15 mock treatment 502843.0 73500.0 0.44 434859.0 -21700.0 -0.12 0.2217 0.4881 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D16 mock treatment 427054.0 -2330.0 -0.01 341618.0 -115000.0 -0.65 -0.4721 -0.722 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D17 compound treatment 397756.0 -31600.0 -0.19 392544.0 -64000.0 -0.36 -0.3907 -0.9528 3070637 PK04_107077 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D18 compound treatment 438548.0 9160.0 0.05 394522.0 -62100.0 -0.35 -0.211 -0.5909 3188786 PK04_107078 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D19 compound treatment 529063.0 99700.0 0.59 364077.0 -92500.0 -0.53 0.0474 0.0598 3188787 PK04_107079 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D20 compound treatment 417799.0 -11600.0 -0.07 389656.0 -66900.0 -0.38 -0.3179 -0.8218 3070641 PK04_107080 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D21 compound treatment 532966.0 104000.0 0.62 439121.0 -17500.0 -0.1 0.3656 0.5856 3188905 PK04_107081 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D22 compound treatment 472317.0 42900.0 0.26 446152.0 -10400.0 -0.06 0.1387 0.5287 3188906 PK04_107082 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D23 compound treatment 600298.0 171000.0 1.02 569946.0 113000.0 0.64 1.1751 0.9758 3070684 PK04_107083 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 D24 compound treatment 635093.0 206000.0 1.22 517356.0 60800.0 0.35 1.11 0.8726 3188907 PK04_107084 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E01 mock treatment 527598.0 98200.0 0.58 514794.0 58200.0 0.33 0.6473 0.9637 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E02 mock treatment 459343.0 30000.0 0.18 486080.0 29500.0 0.17 0.2446 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E03 compound treatment 453101.0 23700.0 0.14 562778.0 106000.0 0.6 0.5268 0.8495 3220739 PK04_107085 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E04 compound treatment 427939.0 -1450.0 -0.01 491415.0 34800.0 0.2 0.1339 0.6757 3070690 PK04_107086 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E05 compound treatment 445210.0 15800.0 0.09 509039.0 52400.0 0.3 0.2775 0.8872 3220741 PK04_107087 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E06 compound treatment 374556.0 -54800.0 -0.33 391152.0 -65400.0 -0.37 -0.4939 -0.9979 3070694 PK04_107088 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E07 compound treatment 410997.0 -18400.0 -0.11 473485.0 16900.0 0.1 -0.0095 -0.065 3220743 PK04_107089 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E08 compound treatment 448823.0 19400.0 0.12 454128.0 -2470.0 -0.01 0.0719 0.6169 3188910 PK04_107090 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E09 mock treatment 446326.0 16900.0 0.1 444579.0 -12000.0 -0.07 0.023 0.1887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E10 mock treatment 409088.0 -20300.0 -0.12 429284.0 -27300.0 -0.16 -0.1952 -0.9923 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E11 compound treatment 404325.0 -25100.0 -0.15 483893.0 27300.0 0.16 0.0043 0.02 3188911 PK04_107091 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E12 compound treatment 330492.0 -98900.0 -0.59 396039.0 -60600.0 -0.34 -0.6597 -0.9674 3070742 PK04_107092 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E13 compound treatment 427849.0 -1540.0 -0.01 406674.0 -49900.0 -0.28 -0.2072 -0.7295 3188912 PK04_107093 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E14 compound treatment 357291.0 -72100.0 -0.43 428051.0 -28500.0 -0.16 -0.4182 -0.9116 3070746 PK04_107094 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E15 compound treatment 502334.0 72900.0 0.43 448157.0 -8440.0 -0.05 0.2731 0.6252 3188913 PK04_107095 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E16 compound treatment 345510.0 -83900.0 -0.5 247521.0 -209000.0 -1.19 -1.1937 -0.9257 3070750 PK04_107096 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E17 mock treatment 254464.0 -175000.0 -1.04 170786.0 -286000.0 -1.63 -1.8854 -0.9768 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E18 mock treatment 199487.0 -230000.0 -1.37 189039.0 -268000.0 -1.52 -2.0434 -0.9986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E19 compound treatment 407248.0 -22100.0 -0.13 421935.0 -34700.0 -0.2 -0.2325 -0.9808 3220747 PK04_107097 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E20 compound treatment 366342.0 -63000.0 -0.38 324886.0 -132000.0 -0.75 -0.7949 -0.9489 3188915 PK04_107098 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E21 compound treatment 449594.0 20200.0 0.12 503944.0 47400.0 0.27 0.2754 0.934 3220749 PK04_107099 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E22 compound treatment 269423.0 -160000.0 -0.95 230230.0 -226000.0 -1.29 -1.5834 -0.989 3070803 PK04_107100 CC(C)[Si](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)(C#Cc3ccc(Oc4ccccc4)cc3)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E23 compound treatment 406554.0 -22800.0 -0.14 335986.0 -121000.0 -0.69 -0.5811 -0.8311 3220751 PK04_107101 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 E24 compound treatment 176238.0 -253000.0 -1.51 481863.0 25300.0 0.14 -0.9637 -0.6368 3070808 PK04_107102 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F01 mock treatment 495293.0 65900.0 0.39 602829.0 146000.0 0.83 0.8654 0.9412 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F02 mock treatment 479130.0 49700.0 0.3 364963.0 -91600.0 -0.52 -0.1591 -0.2655 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F03 compound treatment 399160.0 -30200.0 -0.18 506215.0 49600.0 0.28 0.0723 0.2161 3188918 PK04_107103 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F04 compound treatment 461303.0 31900.0 0.19 564829.0 108000.0 0.62 0.5695 0.8842 3188919 PK04_107104 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F05 compound treatment 477065.0 47700.0 0.28 531522.0 74900.0 0.43 0.5019 0.9805 3188920 PK04_107105 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F06 compound treatment 487044.0 57700.0 0.34 453380.0 -3210.0 -0.02 0.2297 0.6685 3188921 PK04_107106 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F07 compound treatment 429551.0 164.0 0.0 478487.0 21900.0 0.12 0.0887 0.7126 3070852 PK04_107107 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F08 compound treatment 440685.0 11300.0 0.07 335964.0 -121000.0 -0.69 -0.4375 -0.6348 3188922 PK04_107108 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F09 mock treatment 451316.0 21900.0 0.13 474384.0 17800.0 0.1 0.1638 0.9921 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F10 mock treatment 504677.0 75300.0 0.45 483017.0 26400.0 0.15 0.4231 0.8952 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F11 compound treatment 469465.0 40100.0 0.24 505338.0 48700.0 0.28 0.3647 0.9972 3189029 PK04_107109 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F12 compound treatment 460659.0 31300.0 0.19 454980.0 -1610.0 -0.01 0.1251 0.6714 3070859 PK04_107110 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F13 compound treatment 447700.0 18300.0 0.11 442721.0 -13900.0 -0.08 0.0213 0.1582 3189030 PK04_107111 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F14 compound treatment 396116.0 -33300.0 -0.2 388913.0 -67700.0 -0.38 -0.4122 -0.9523 3189031 PK04_107112 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F15 compound treatment 479465.0 50100.0 0.3 536480.0 79900.0 0.45 0.532 0.9791 3070862 PK04_107113 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F16 compound treatment 402283.0 -27100.0 -0.16 193214.0 -263000.0 -1.5 -1.1731 -0.7788 3189032 PK04_107114 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F17 mock treatment 180159.0 -249000.0 -1.48 184737.0 -272000.0 -1.55 -2.142 -0.9998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F18 mock treatment 481506.0 52100.0 0.31 240452.0 -216000.0 -1.23 -0.6498 -0.5126 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F19 compound treatment 534441.0 105000.0 0.63 439194.0 -17400.0 -0.1 0.3721 0.5879 3189033 PK04_107115 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F20 compound treatment 241721.0 -188000.0 -1.12 519772.0 63200.0 0.36 -0.5357 -0.4566 3070022 PK04_107116 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F21 compound treatment 530586.0 101000.0 0.6 469842.0 13200.0 0.08 0.4792 0.7894 3189034 PK04_107117 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F22 compound treatment 482277.0 52900.0 0.31 448750.0 -7840.0 -0.04 0.191 0.6009 3189035 PK04_107118 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F23 compound treatment 529210.0 99800.0 0.59 452104.0 -4490.0 -0.03 0.402 0.6761 3070031 PK04_107119 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 F24 compound treatment 606747.0 177000.0 1.06 495396.0 38800.0 0.22 0.9024 0.8368 3189036 PK04_107120 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G01 compound treatment 468680.0 39300.0 0.23 537313.0 80700.0 0.46 0.4899 0.951 3220772 PK04_107121 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G02 compound treatment 455714.0 26300.0 0.16 500309.0 43700.0 0.25 0.2866 0.9752 3070078 PK04_107122 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G03 mock treatment 490065.0 60700.0 0.36 512003.0 55400.0 0.32 0.4782 0.9977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G04 mock treatment 158042.0 -271000.0 -1.61 438004.0 -18600.0 -0.11 -1.2166 -0.7518 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G05 compound treatment 468991.0 39600.0 0.24 471429.0 14800.0 0.08 0.2263 0.904 3220775 PK04_107123 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G06 compound treatment 77620.0 -352000.0 -2.09 76939.0 -380000.0 -2.16 -3.007 -0.9999 3070081 PK04_107124 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G07 compound treatment 481153.0 51800.0 0.31 469247.0 12700.0 0.07 0.2687 0.8494 3189039 PK04_107125 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G08 compound treatment 356967.0 -72400.0 -0.43 399999.0 -56600.0 -0.32 -0.5323 -0.9896 3189040 PK04_107126 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G09 compound treatment 401682.0 -27700.0 -0.16 477269.0 20700.0 0.12 -0.0334 -0.1652 3070086 PK04_107127 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G10 compound treatment 314323.0 -115000.0 -0.68 319875.0 -137000.0 -0.78 -1.034 -0.998 3189041 PK04_107128 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G11 compound treatment 380850.0 -48500.0 -0.29 478355.0 21800.0 0.12 -0.1167 -0.3715 3070089 PK04_107129 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G12 compound treatment 157169.0 -272000.0 -1.62 90341.0 -366000.0 -2.08 -2.6183 -0.9923 3189042 PK04_107130 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G13 compound treatment 270697.0 -159000.0 -0.94 532023.0 75400.0 0.43 -0.3645 -0.3514 3070134 PK04_107131 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G14 compound treatment 253232.0 -176000.0 -1.05 511367.0 54800.0 0.31 -0.5211 -0.4764 3070137 PK04_107132 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G15 compound treatment 181014.0 -248000.0 -1.48 470120.0 13500.0 0.08 -0.9908 -0.6694 3189043 PK04_107133 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G16 compound treatment 377950.0 -51400.0 -0.31 141947.0 -315000.0 -1.79 -1.4817 -0.8162 3189044 PK04_107134 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G17 compound treatment 391512.0 -37900.0 -0.23 105653.0 -351000.0 -2.0 -1.5706 -0.782 3070143 PK04_107135 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G18 compound treatment 163234.0 -266000.0 -1.58 188476.0 -268000.0 -1.52 -2.1982 -0.9998 3189045 PK04_107136 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G19 mock treatment 184911.0 -244000.0 -1.45 227648.0 -229000.0 -1.3 -1.9494 -0.9985 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G20 mock treatment 195877.0 -234000.0 -1.39 292079.0 -165000.0 -0.94 -1.6442 -0.9815 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G21 compound treatment 401201.0 -28200.0 -0.17 465251.0 8660.0 0.05 -0.0838 -0.4793 3070191 PK04_107137 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G22 compound treatment 45044.0 -384000.0 -2.29 62579.0 -394000.0 -2.24 -3.2018 -0.9999 3189046 PK04_107138 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G23 compound treatment 423738.0 -5650.0 -0.03 458303.0 1710.0 0.01 -0.0169 -0.4828 3070196 PK04_107139 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 G24 compound treatment 404979.0 -24400.0 -0.15 109112.0 -347000.0 -1.98 -1.5 -0.757 3189047 PK04_107140 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H01 compound treatment 299957.0 -129000.0 -0.77 550022.0 93400.0 0.53 -0.169 -0.1806 3189157 PK04_107141 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H02 compound treatment 259464.0 -170000.0 -1.01 540126.0 83500.0 0.48 -0.3792 -0.3394 3189158 PK04_107142 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H03 mock treatment 326963.0 -102000.0 -0.61 458790.0 2200.0 0.01 -0.4222 -0.6925 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H04 mock treatment 312126.0 -117000.0 -0.7 512148.0 55600.0 0.32 -0.2701 -0.3526 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H05 compound treatment 462618.0 33200.0 0.2 491089.0 34500.0 0.2 0.2786 1.0 3070201 PK04_107143 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H06 compound treatment 216775.0 -213000.0 -1.27 484940.0 28300.0 0.16 -0.7807 -0.6121 3189159 PK04_107144 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H07 compound treatment 273754.0 -156000.0 -0.93 236293.0 -220000.0 -1.25 -1.5408 -0.989 3071172 PK04_107145 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H08 compound treatment 281718.0 -148000.0 -0.88 466763.0 10200.0 0.06 -0.5805 -0.6591 3071173 PK04_107146 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H09 compound treatment 235406.0 -194000.0 -1.15 448724.0 -7870.0 -0.04 -0.848 -0.734 3071174 PK04_107147 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H10 compound treatment 234023.0 -195000.0 -1.16 239009.0 -218000.0 -1.24 -1.6971 -0.9995 3189160 PK04_107148 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H11 compound treatment 262855.0 -167000.0 -0.99 510420.0 53800.0 0.31 -0.4844 -0.467 3189161 PK04_107149 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H12 compound treatment 243627.0 -186000.0 -1.11 418217.0 -38400.0 -0.22 -0.936 -0.8307 3071175 PK04_107150 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H13 compound treatment 196232.0 -233000.0 -1.39 509391.0 52800.0 0.3 -0.7689 -0.5416 3189162 PK04_107151 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H14 compound treatment 459000.0 29600.0 0.18 297842.0 -159000.0 -0.9 -0.5137 -0.5585 3189163 PK04_107152 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H15 compound treatment 524942.0 95600.0 0.57 224413.0 -232000.0 -1.32 -0.5315 -0.3697 3071176 PK04_107153 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H16 compound treatment 390813.0 -38600.0 -0.23 110672.0 -346000.0 -1.97 -1.5533 -0.7843 3189164 PK04_107154 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H17 compound treatment 175991.0 -253000.0 -1.51 149283.0 -307000.0 -1.75 -2.3021 -0.9973 3189165 PK04_107155 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H18 compound treatment 508786.0 79400.0 0.47 492090.0 35500.0 0.2 0.4769 0.928 3071177 PK04_107156 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H19 mock treatment 272713.0 -157000.0 -0.93 436810.0 -19800.0 -0.11 -0.7389 -0.7867 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H20 mock treatment 268065.0 -161000.0 -0.96 479607.0 23000.0 0.13 -0.5863 -0.6051 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H21 compound treatment 532229.0 103000.0 0.61 283104.0 -173000.0 -0.99 -0.2648 -0.2281 3189166 PK04_107157 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H22 compound treatment 601671.0 172000.0 1.03 492068.0 35500.0 0.2 0.8677 0.8303 3189167 PK04_107158 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H23 compound treatment 533739.0 104000.0 0.62 543042.0 86400.0 0.49 0.7868 0.9933 3071178 PK04_107159 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 H24 compound treatment 539720.0 110000.0 0.66 560201.0 104000.0 0.59 0.8809 0.9985 3189168 PK04_107160 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I01 compound treatment 444185.0 14800.0 0.09 502833.0 46200.0 0.26 0.2482 0.8951 3071179 PK04_107161 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I02 compound treatment 243772.0 -186000.0 -1.1 232824.0 -224000.0 -1.27 -1.6809 -0.9975 3189169 PK04_107162 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I03 compound treatment 447640.0 18300.0 0.11 494175.0 37600.0 0.21 0.2279 0.9508 3071180 PK04_107163 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I04 compound treatment 163115.0 -266000.0 -1.58 195425.0 -261000.0 -1.49 -2.1707 -0.9995 3189170 PK04_107164 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I05 mock treatment 447758.0 18400.0 0.11 507053.0 50500.0 0.29 0.2802 0.9125 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I06 mock treatment 410363.0 -19000.0 -0.11 494383.0 37800.0 0.21 0.0719 0.296 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I07 compound treatment 201100.0 -228000.0 -1.36 222003.0 -235000.0 -1.33 -1.904 -1.0 3071181 PK04_107165 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I08 compound treatment 110066.0 -319000.0 -1.9 92058.0 -365000.0 -2.07 -2.8096 -0.9991 3189171 PK04_107166 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I09 compound treatment 80368.0 -349000.0 -2.08 94163.0 -362000.0 -2.06 -2.9262 -1.0 3189172 PK04_107167 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I10 compound treatment 465198.0 35800.0 0.21 500115.0 43500.0 0.25 0.3257 0.9972 3071182 PK04_107168 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I11 compound treatment 255180.0 -174000.0 -1.04 486476.0 29900.0 0.17 -0.6129 -0.5834 3189173 PK04_107169 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I12 compound treatment 69275.0 -360000.0 -2.14 82140.0 -374000.0 -2.13 -3.0212 -1.0 3189286 PK04_107170 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I13 compound treatment 423543.0 -5840.0 -0.03 510289.0 53700.0 0.31 0.1913 0.6225 3071183 PK04_107171 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I14 compound treatment 28172.0 -401000.0 -2.39 83586.0 -373000.0 -2.12 -3.1883 -0.9983 3189287 PK04_107172 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I15 compound treatment 185582.0 -244000.0 -1.45 181057.0 -276000.0 -1.57 -2.134 -0.9993 3071184 PK04_107173 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I16 compound treatment 293375.0 -136000.0 -0.81 147339.0 -309000.0 -1.76 -1.8159 -0.938 3189288 PK04_107174 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I17 compound treatment 573347.0 144000.0 0.86 161809.0 -295000.0 -1.68 -0.5795 -0.3078 3071185 PK04_107175 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I18 compound treatment 60067.0 -369000.0 -2.2 61092.0 -396000.0 -2.25 -3.1446 -0.9999 3189289 PK04_107176 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I19 compound treatment 490106.0 60700.0 0.36 193190.0 -263000.0 -1.5 -0.8037 -0.5216 3071186 PK04_107177 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I20 compound treatment 103858.0 -326000.0 -1.94 157930.0 -299000.0 -1.7 -2.5709 -0.9978 3189171 PK04_107178 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I21 mock treatment 471502.0 42100.0 0.25 225988.0 -231000.0 -1.31 -0.7501 -0.5618 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I22 mock treatment 464241.0 34900.0 0.21 402938.0 -53700.0 -0.31 -0.0691 -0.1872 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I23 compound treatment 487211.0 57800.0 0.34 482445.0 25900.0 0.15 0.3473 0.928 3189290 PK04_107179 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 I24 compound treatment 188219.0 -241000.0 -1.44 297288.0 -159000.0 -0.91 -1.6555 -0.9754 3071182 PK04_107180 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J01 compound treatment 290621.0 -139000.0 -0.83 503876.0 47300.0 0.27 -0.3938 -0.4535 3189291 PK04_107181 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J02 compound treatment 418181.0 -11200.0 -0.07 502844.0 46300.0 0.26 0.1388 0.5116 3071187 PK04_107182 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J03 compound treatment 477742.0 48400.0 0.29 493864.0 37300.0 0.21 0.3534 0.9887 3189292 PK04_107183 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J04 compound treatment 461855.0 32500.0 0.19 511617.0 55000.0 0.31 0.3579 0.9732 3189293 PK04_107184 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J05 mock treatment 453746.0 24400.0 0.14 515126.0 58500.0 0.33 0.3379 0.9306 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J06 mock treatment 470212.0 40800.0 0.24 485331.0 28700.0 0.16 0.2874 0.9814 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J07 compound treatment 189961.0 -239000.0 -1.42 283684.0 -173000.0 -0.98 -1.7029 -0.9836 3071188 PK04_107185 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J08 compound treatment 502919.0 73500.0 0.44 311911.0 -145000.0 -0.82 -0.2723 -0.2922 3189294 PK04_107186 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J09 compound treatment 392098.0 -37300.0 -0.22 269032.0 -188000.0 -1.07 -0.9111 -0.8363 3189295 PK04_107187 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J10 compound treatment 192955.0 -236000.0 -1.41 537366.0 80800.0 0.46 -0.6702 -0.4528 3071189 PK04_107188 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J11 compound treatment 545583.0 116000.0 0.69 622660.0 166000.0 0.94 1.1568 0.9883 3189296 PK04_107189 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J12 compound treatment 541072.0 112000.0 0.66 358012.0 -98600.0 -0.56 0.0736 0.0846 3189297 PK04_107190 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J13 compound treatment 367004.0 -62400.0 -0.37 497952.0 41400.0 0.24 -0.0962 -0.2189 3071190 PK04_107191 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J14 compound treatment 486995.0 57600.0 0.34 192222.0 -264000.0 -1.5 -0.8206 -0.5322 3189298 PK04_107192 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J15 compound treatment 204753.0 -225000.0 -1.34 464147.0 7550.0 0.04 -0.9149 -0.684 3071191 PK04_107193 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J16 compound treatment 329105.0 -100000.0 -0.6 260263.0 -196000.0 -1.12 -1.2115 -0.957 3189299 PK04_107194 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J17 compound treatment 380175.0 -49200.0 -0.29 487697.0 31100.0 0.18 -0.082 -0.2397 3189300 PK04_107195 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J18 compound treatment 423728.0 -5660.0 -0.03 478209.0 21600.0 0.12 0.0631 0.4951 3071192 PK04_107196 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J19 compound treatment 493957.0 64600.0 0.38 504953.0 48400.0 0.28 0.4662 0.9865 3189301 PK04_107197 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J20 compound treatment 260251.0 -169000.0 -1.01 435448.0 -21100.0 -0.12 -0.7968 -0.786 3189302 PK04_107198 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J21 mock treatment 512199.0 82800.0 0.49 421212.0 -35400.0 -0.2 0.2062 0.3874 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J22 mock treatment 513827.0 84400.0 0.5 431038.0 -25600.0 -0.15 0.2526 0.4828 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J23 compound treatment 518882.0 89500.0 0.53 527226.0 70600.0 0.4 0.6606 0.9903 3071251 PK04_107199 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 J24 compound treatment 488954.0 59600.0 0.35 607134.0 151000.0 0.86 0.856 0.9238 3189414 PK04_107200 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K01 compound treatment 468661.0 39300.0 0.23 559569.0 103000.0 0.59 0.5794 0.9189 3071252 PK04_107201 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K02 compound treatment 499703.0 70300.0 0.42 548339.0 91700.0 0.52 0.6648 0.994 3189415 PK04_107202 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K03 compound treatment 510672.0 81300.0 0.48 557972.0 101000.0 0.58 0.7497 0.9962 3071253 PK04_107203 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K04 compound treatment 239090.0 -190000.0 -1.13 277105.0 -179000.0 -1.02 -1.5226 -0.9987 3189416 PK04_107204 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K05 compound treatment 411657.0 -17700.0 -0.11 552218.0 95600.0 0.54 0.3099 0.5595 3189417 PK04_107205 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K06 compound treatment 85014.0 -344000.0 -2.05 86208.0 -370000.0 -2.11 -2.9386 -0.9999 3071254 PK04_107206 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K07 mock treatment 451067.0 21700.0 0.13 542807.0 86200.0 0.49 0.4379 0.8638 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K08 mock treatment 518238.0 88900.0 0.53 571923.0 115000.0 0.66 0.8377 0.9943 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K09 compound treatment 507113.0 77700.0 0.46 541980.0 85400.0 0.49 0.6704 0.9997 3071255 PK04_107207 NC(=N)NCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K10 compound treatment 281845.0 -148000.0 -0.88 410509.0 -46100.0 -0.26 -0.8062 -0.8798 3189418 PK04_107208 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K11 compound treatment 501137.0 71700.0 0.43 512608.0 56000.0 0.32 0.5272 0.9896 3189419 PK04_107209 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K12 compound treatment 74037.0 -355000.0 -2.11 76419.0 -380000.0 -2.16 -3.0241 -0.9999 3071256 PK04_107210 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K13 compound treatment 216444.0 -213000.0 -1.27 516111.0 59500.0 0.34 -0.6568 -0.5007 3189420 PK04_107211 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K14 compound treatment 77259.0 -352000.0 -2.1 86762.0 -370000.0 -2.1 -2.969 -1.0 3071257 PK04_107212 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K15 mock treatment 92881.0 -337000.0 -2.0 470214.0 13600.0 0.08 -1.3613 -0.6792 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K16 mock treatment 349643.0 -79700.0 -0.47 511747.0 55200.0 0.31 -0.1138 -0.2001 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K17 compound treatment 502585.0 73200.0 0.44 532145.0 75600.0 0.43 0.6118 1.0 1035256 PK04_107213 C#CCNCc1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K18 compound treatment 319871.0 -110000.0 -0.65 350562.0 -106000.0 -0.6 -0.8872 -0.9992 3189421 PK04_107214 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K19 compound treatment 490425.0 61000.0 0.36 536811.0 80200.0 0.46 0.5794 0.9936 3071258 PK04_107215 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K20 compound treatment 50754.0 -379000.0 -2.25 68214.0 -388000.0 -2.21 -3.1551 -0.9999 3189422 PK04_107216 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K21 compound treatment 500943.0 71600.0 0.43 470589.0 14000.0 0.08 0.3574 0.825 3189423 PK04_107217 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K22 compound treatment 253971.0 -175000.0 -1.04 192217.0 -264000.0 -1.5 -1.8013 -0.9841 3071259 PK04_107218 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K23 mock treatment 476077.0 46700.0 0.28 439363.0 -17200.0 -0.1 0.1272 0.4317 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 K24 mock treatment 337660.0 -91700.0 -0.55 456245.0 -348.0 0.0 -0.3874 -0.7097 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L01 compound treatment 513193.0 83800.0 0.5 574459.0 118000.0 0.67 0.8266 0.9894 3189424 PK04_107219 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L02 compound treatment 482708.0 53300.0 0.32 492742.0 36100.0 0.21 0.3698 0.9779 3189425 PK04_107220 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L03 compound treatment 337108.0 -92300.0 -0.55 497972.0 41400.0 0.24 -0.2219 -0.3715 3071260 PK04_107221 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L04 compound treatment 514986.0 85600.0 0.51 529839.0 73200.0 0.42 0.6548 0.995 3189426 PK04_107222 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L05 compound treatment 550171.0 121000.0 0.72 542397.0 85800.0 0.49 0.8533 0.9822 3189427 PK04_107223 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L06 compound treatment 532470.0 103000.0 0.61 529533.0 72900.0 0.41 0.7271 0.9818 3071261 PK04_107224 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L07 mock treatment 378380.0 -51000.0 -0.3 523849.0 67300.0 0.38 0.0558 0.1143 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L08 mock treatment 511545.0 82200.0 0.49 496989.0 40400.0 0.23 0.5082 0.9407 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L09 compound treatment 541577.0 112000.0 0.67 554420.0 97800.0 0.56 0.8655 0.9959 3189428 PK04_107225 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L10 compound treatment 302353.0 -127000.0 -0.76 490134.0 33500.0 0.19 -0.3997 -0.5126 3189429 PK04_107226 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L11 compound treatment 557375.0 128000.0 0.76 538134.0 81500.0 0.46 0.8665 0.9717 3071262 PK04_107227 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L12 compound treatment 489799.0 60400.0 0.36 509571.0 53000.0 0.3 0.4673 0.9961 3189430 PK04_107228 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L13 compound treatment 474636.0 45200.0 0.27 508334.0 51700.0 0.29 0.3985 0.999 3189431 PK04_107229 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L14 compound treatment 466071.0 36700.0 0.22 491204.0 34600.0 0.2 0.2936 0.9987 3071263 PK04_107230 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L15 mock treatment 466437.0 37000.0 0.22 519828.0 63200.0 0.36 0.4102 0.9724 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L16 mock treatment 542383.0 113000.0 0.67 489479.0 32900.0 0.19 0.6078 0.8707 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L17 compound treatment 461444.0 32100.0 0.19 200535.0 -256000.0 -1.46 -0.8947 -0.6093 3189432 PK04_107231 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L18 compound treatment 191882.0 -238000.0 -1.41 492704.0 36100.0 0.21 -0.8543 -0.5981 3189547 PK04_107232 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L19 compound treatment 428565.0 -822.0 0.0 413380.0 -43200.0 -0.25 -0.1772 -0.721 3071264 PK04_107233 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L20 compound treatment 312083.0 -117000.0 -0.7 488087.0 31500.0 0.18 -0.367 -0.5092 3189548 PK04_107234 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L21 compound treatment 171929.0 -257000.0 -1.53 201998.0 -255000.0 -1.45 -2.1072 -0.9996 3189549 PK04_107235 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L22 compound treatment 478434.0 49000.0 0.29 502869.0 46300.0 0.26 0.3925 0.9987 3071265 PK04_107236 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L23 mock treatment 481973.0 52600.0 0.31 464128.0 7530.0 0.04 0.2516 0.7965 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 L24 mock treatment 485897.0 56500.0 0.34 227962.0 -229000.0 -1.3 -0.6815 -0.5075 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M01 compound treatment 508561.0 79200.0 0.47 608457.0 152000.0 0.86 0.9439 0.9594 3189550 PK04_107237 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M02 compound treatment 410621.0 -18800.0 -0.11 350752.0 -106000.0 -0.6 -0.5046 -0.8242 3071266 PK04_107238 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M03 compound treatment 553714.0 124000.0 0.74 571752.0 115000.0 0.65 0.9863 0.9981 3189551 PK04_107239 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M04 compound treatment 526464.0 97100.0 0.58 606236.0 150000.0 0.85 1.0103 0.9822 3189552 PK04_107240 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M05 compound treatment 527620.0 98200.0 0.58 531957.0 75400.0 0.43 0.7164 0.9883 3071267 PK04_107241 CN(C)S(=O)(=O)NCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M06 compound treatment 456848.0 27500.0 0.16 501821.0 45200.0 0.26 0.2974 0.976 3189553 PK04_107242 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M07 compound treatment 497555.0 68200.0 0.41 550631.0 94000.0 0.53 0.665 0.9907 3414058 PK04_107243 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M08 compound treatment 503067.0 73700.0 0.44 512182.0 55600.0 0.32 0.5336 0.9871 3189554 PK04_107244 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M09 mock treatment 509729.0 80300.0 0.48 567299.0 111000.0 0.63 0.7833 0.9908 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M10 mock treatment 504557.0 75200.0 0.45 569039.0 112000.0 0.64 0.7685 0.9847 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M11 compound treatment 480414.0 51000.0 0.3 514344.0 57800.0 0.33 0.447 0.9992 3189555 PK04_107245 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M12 compound treatment 459120.0 29700.0 0.18 518673.0 62100.0 0.35 0.3748 0.949 3071269 PK04_107246 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M13 mock treatment 497617.0 68200.0 0.41 489927.0 33300.0 0.19 0.4212 0.9398 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M14 mock treatment 493786.0 64400.0 0.38 530971.0 74400.0 0.42 0.5701 0.9988 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M15 compound treatment 114401.0 -315000.0 -1.87 483651.0 27100.0 0.15 -1.2167 -0.6469 3189556 PK04_107247 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M16 compound treatment 371740.0 -57600.0 -0.34 370588.0 -86000.0 -0.49 -0.5884 -0.985 3189557 PK04_107248 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M17 compound treatment 498910.0 69500.0 0.41 582753.0 126000.0 0.72 0.7999 0.9658 3189558 PK04_107249 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M18 compound treatment 245408.0 -184000.0 -1.09 349325.0 -107000.0 -0.61 -1.2056 -0.9619 3071329 PK04_107250 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M19 compound treatment 579974.0 151000.0 0.9 505231.0 48600.0 0.28 0.8293 0.8842 3189559 PK04_107251 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M20 compound treatment 300673.0 -129000.0 -0.77 325700.0 -131000.0 -0.74 -1.068 -0.9999 3071330 PK04_107252 CCCC#C[Si](O[C@H](CC)c1cn(Cc2cccc(Cl)c2)nn1)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M21 compound treatment 443583.0 14200.0 0.08 475423.0 18800.0 0.11 0.1355 0.9931 3189560 PK04_107253 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M22 compound treatment 334468.0 -94900.0 -0.56 228333.0 -228000.0 -1.3 -1.3173 -0.9305 3071331 PK04_107254 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M23 compound treatment 124510.0 -305000.0 -1.81 534267.0 77700.0 0.44 -0.9707 -0.5198 3189561 PK04_107255 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 M24 compound treatment 435685.0 6300.0 0.04 490437.0 33800.0 0.19 0.1626 0.8292 3071332 PK04_107256 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N01 compound treatment 543058.0 114000.0 0.68 532593.0 76000.0 0.43 0.784 0.9766 3189562 PK04_107257 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N02 compound treatment 497446.0 68100.0 0.41 534089.0 77500.0 0.44 0.598 0.9991 3189563 PK04_107258 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N03 compound treatment 386403.0 -43000.0 -0.26 463059.0 6470.0 0.04 -0.1549 -0.5993 3071333 PK04_107259 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N04 compound treatment 287551.0 -142000.0 -0.84 496646.0 40100.0 0.23 -0.4358 -0.4985 3189564 PK04_107260 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N05 compound treatment 476481.0 47100.0 0.28 524278.0 67700.0 0.38 0.4704 0.9879 3189681 PK04_107261 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N06 compound treatment 375056.0 -54300.0 -0.32 548910.0 92300.0 0.52 0.1426 0.2312 3071334 PK04_107262 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N07 compound treatment 231792.0 -198000.0 -1.18 443061.0 -13500.0 -0.08 -0.886 -0.7518 3189682 PK04_107263 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N08 compound treatment 249267.0 -180000.0 -1.07 578888.0 122000.0 0.7 -0.2662 -0.2084 3071335 PK04_107264 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N09 mock treatment 536550.0 107000.0 0.64 495685.0 39100.0 0.22 0.6082 0.9004 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N10 mock treatment 426404.0 -2980.0 -0.02 540527.0 83900.0 0.48 0.325 0.6803 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N11 compound treatment 410244.0 -19100.0 -0.11 464881.0 8290.0 0.05 -0.0472 -0.3831 3189683 PK04_107265 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N12 compound treatment 580911.0 152000.0 0.9 567802.0 111000.0 0.63 1.0848 0.9849 3189684 PK04_107266 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N13 mock treatment 235888.0 -193000.0 -1.15 551693.0 95100.0 0.54 -0.4319 -0.3395 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N14 mock treatment 521907.0 92500.0 0.55 546873.0 90300.0 0.51 0.7524 0.9994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N15 compound treatment 524791.0 95400.0 0.57 609463.0 153000.0 0.87 1.0162 0.9787 3071336 PK04_107267 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N16 compound treatment 473585.0 44200.0 0.26 474979.0 18400.0 0.1 0.2599 0.9183 3189685 PK04_107268 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N17 compound treatment 245468.0 -184000.0 -1.09 613432.0 157000.0 0.89 -0.1433 -0.1015 3189686 PK04_107269 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N18 compound treatment 431190.0 1800.0 0.01 352672.0 -104000.0 -0.59 -0.4103 -0.6942 3071337 PK04_107270 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N19 compound treatment 579999.0 151000.0 0.9 583424.0 127000.0 0.72 1.1438 0.9942 3189687 PK04_107271 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N20 compound treatment 302896.0 -126000.0 -0.75 523785.0 67200.0 0.38 -0.2621 -0.3105 3189688 PK04_107272 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N21 compound treatment 189239.0 -240000.0 -1.43 552957.0 96400.0 0.55 -0.6231 -0.4071 3071339 PK04_107273 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N22 compound treatment 532162.0 103000.0 0.61 490126.0 33500.0 0.19 0.5673 0.8855 3189689 PK04_107274 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N23 compound treatment 530680.0 101000.0 0.6 575925.0 119000.0 0.68 0.9061 0.9983 3189690 PK04_107275 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 N24 compound treatment 525904.0 96500.0 0.57 487849.0 31300.0 0.18 0.5319 0.8845 3071341 PK04_107276 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O01 compound treatment 568957.0 140000.0 0.83 604159.0 148000.0 0.84 1.1807 1.0 3414059 PK04_107277 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O02 compound treatment 377772.0 -51600.0 -0.31 466404.0 9810.0 0.06 -0.1778 -0.5694 3189692 PK04_107278 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O03 compound treatment 538353.0 109000.0 0.65 544741.0 88100.0 0.5 0.813 0.9919 3414060 PK04_107279 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O04 compound treatment 504758.0 75400.0 0.45 497429.0 40800.0 0.23 0.4814 0.953 3189693 PK04_107280 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O05 compound treatment 532085.0 103000.0 0.61 599491.0 143000.0 0.81 1.0068 0.9901 3071393 PK04_107281 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O06 compound treatment 491920.0 62500.0 0.37 447524.0 -9070.0 -0.05 0.2267 0.6034 3189694 PK04_107282 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O07 compound treatment 495732.0 66300.0 0.39 548307.0 91700.0 0.52 0.648 0.9906 3189695 PK04_107283 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O08 compound treatment 480451.0 51100.0 0.3 513623.0 57000.0 0.32 0.4442 0.9995 3071395 PK04_107284 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O09 compound treatment 558578.0 129000.0 0.77 564266.0 108000.0 0.61 0.9766 0.9936 3189696 PK04_107285 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O10 compound treatment 470191.0 40800.0 0.24 456537.0 -56.0 0.0 0.1715 0.7062 3189697 PK04_107286 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O11 mock treatment 518769.0 89400.0 0.53 549727.0 93100.0 0.53 0.7507 1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O12 mock treatment 275120.0 -154000.0 -0.92 495164.0 38600.0 0.22 -0.4941 -0.5234 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O13 compound treatment 541440.0 112000.0 0.67 485412.0 28800.0 0.16 0.5874 0.8554 3071396 PK04_107287 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O14 compound treatment 304416.0 -125000.0 -0.74 367897.0 -88700.0 -0.5 -0.8826 -0.9821 3187592 PK04_107288 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O15 compound treatment 181639.0 -248000.0 -1.47 443465.0 -13100.0 -0.07 -1.0954 -0.742 3187593 PK04_107289 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O16 compound treatment 438255.0 8870.0 0.05 433140.0 -23500.0 -0.13 -0.057 -0.3973 3071397 PK04_107290 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O17 compound treatment 409675.0 -19700.0 -0.12 379852.0 -76700.0 -0.44 -0.3915 -0.8664 3187594 PK04_107291 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O18 compound treatment 533783.0 104000.0 0.62 505419.0 48800.0 0.28 0.6357 0.9341 3071398 PK04_107292 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O19 compound treatment 309805.0 -120000.0 -0.71 554508.0 97900.0 0.56 -0.1095 -0.1212 3187595 PK04_107293 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O20 compound treatment 249636.0 -180000.0 -1.07 55014.0 -402000.0 -2.28 -2.3713 -0.9403 3071399 PK04_107294 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O21 compound treatment 504896.0 75500.0 0.45 485437.0 28800.0 0.16 0.4337 0.9067 3187594 PK04_107295 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O22 compound treatment 494859.0 65500.0 0.39 555345.0 98800.0 0.56 0.6726 0.9841 3187596 PK04_107296 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O23 compound treatment 475038.0 45700.0 0.27 477351.0 20800.0 0.12 0.2756 0.9303 3187597 PK04_107297 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 O24 compound treatment 226716.0 -203000.0 -1.21 442804.0 -13800.0 -0.08 -0.9083 -0.7515 3071400 PK04_107298 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P01 compound treatment 420168.0 -9220.0 -0.05 520320.0 63700.0 0.36 0.2175 0.5933 3187598 PK04_107299 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P02 compound treatment 532089.0 103000.0 0.61 561990.0 105000.0 0.6 0.856 1.0 3071401 PK04_107300 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P03 compound treatment 513995.0 84600.0 0.5 522349.0 65800.0 0.37 0.6205 0.9893 3187599 PK04_107301 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P04 compound treatment 494452.0 65100.0 0.39 489102.0 32500.0 0.18 0.4045 0.9428 3187600 PK04_107302 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P05 compound treatment 524399.0 95000.0 0.57 500589.0 44000.0 0.25 0.5768 0.9328 3071402 PK04_107303 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P06 compound treatment 519483.0 90100.0 0.54 463192.0 6600.0 0.04 0.4057 0.7547 3187601 PK04_107304 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P07 compound treatment 549225.0 120000.0 0.71 537646.0 81100.0 0.46 0.8302 0.9777 3187602 PK04_107305 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P08 compound treatment 540430.0 111000.0 0.66 578179.0 122000.0 0.69 0.9562 0.9997 3071403 PK04_107306 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P09 compound treatment 552113.0 123000.0 0.73 532896.0 76300.0 0.43 0.8233 0.9691 3187603 PK04_107307 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P10 compound treatment 517967.0 88600.0 0.53 538931.0 82300.0 0.47 0.7039 0.9983 3187604 PK04_107308 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P11 mock treatment 519510.0 90100.0 0.54 519166.0 62600.0 0.36 0.6309 0.9801 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P12 mock treatment 521969.0 92600.0 0.55 292737.0 -164000.0 -0.93 -0.2693 -0.2487 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P13 compound treatment 570152.0 141000.0 0.84 574933.0 118000.0 0.67 1.0682 0.9941 3071404 PK04_107309 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P14 compound treatment 568866.0 139000.0 0.83 496359.0 39800.0 0.23 0.7469 0.8681 3187605 PK04_107310 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P15 compound treatment 511057.0 81700.0 0.49 547823.0 91200.0 0.52 0.7105 0.9995 3187606 PK04_107311 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P16 compound treatment 556262.0 127000.0 0.76 243734.0 -213000.0 -1.21 -0.322 -0.2257 3071405 PK04_107312 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P17 compound treatment 560765.0 131000.0 0.78 492408.0 35800.0 0.2 0.6969 0.8625 3187607 PK04_107313 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P18 compound treatment 308087.0 -121000.0 -0.72 534390.0 77800.0 0.44 -0.1976 -0.2334 3187608 PK04_107314 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P19 compound treatment 526014.0 96600.0 0.58 528891.0 72300.0 0.41 0.6974 0.9865 3187728 PK04_107315 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P20 compound treatment 502839.0 73500.0 0.44 536731.0 80100.0 0.46 0.6314 0.9998 3071452 PK04_107316 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P21 compound treatment 142507.0 -287000.0 -1.71 587656.0 131000.0 0.75 -0.6803 -0.3651 3187729 PK04_107317 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P22 compound treatment 202598.0 -227000.0 -1.35 443637.0 -13000.0 -0.07 -1.0065 -0.7446 3187730 PK04_107318 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P23 compound treatment 258557.0 -171000.0 -1.02 453388.0 -3210.0 -0.02 -0.7318 -0.7197 3071453 PK04_107319 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2107 P24 compound treatment 428562.0 -825.0 0.0 421729.0 -34900.0 -0.2 -0.1437 -0.7244 3187731 PK04_107320 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A01 compound treatment 497798.0 58400.0 0.35 469272.0 -6810.0 -0.04 0.2183 0.6244 3187732 PK04_108001 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A02 compound treatment 44500.0 -395000.0 -2.35 83885.0 -392000.0 -2.23 -3.239 -0.9997 3071454 PK04_108002 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A03 compound treatment 492955.0 53500.0 0.32 528252.0 52200.0 0.3 0.4351 0.9994 3187733 PK04_108003 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A04 compound treatment 459742.0 20300.0 0.12 563003.0 86900.0 0.49 0.435 0.8549 3071455 PK04_108004 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A05 compound treatment 474658.0 35200.0 0.21 534366.0 58300.0 0.33 0.3826 0.9756 3187734 PK04_108005 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A06 compound treatment 284351.0 -155000.0 -0.92 258100.0 -218000.0 -1.24 -1.5291 -0.9894 3071456 PK04_108006 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A07 compound treatment 217786.0 -222000.0 -1.32 500109.0 24000.0 0.14 -0.8361 -0.6305 3187735 PK04_108007 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A08 compound treatment 212714.0 -227000.0 -1.35 409502.0 -66600.0 -0.38 -1.2218 -0.8719 3071457 PK04_108008 CC(=CCN[C@H](CO)c1ccccc1)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A09 compound treatment 263165.0 -176000.0 -1.05 656360.0 180000.0 1.03 -0.0168 -0.0115 3187736 PK04_108009 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A10 compound treatment 417159.0 -22300.0 -0.13 512782.0 36700.0 0.21 0.0539 0.218 3071458 PK04_108010 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A11 compound treatment 453263.0 13800.0 0.08 512253.0 36200.0 0.21 0.2037 0.9193 3071459 PK04_108011 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A12 compound treatment 65618.0 -374000.0 -2.22 68404.0 -408000.0 -2.32 -3.2124 -0.9998 3187737 PK04_108012 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A13 mock treatment 437372.0 -2050.0 -0.01 668014.0 192000.0 1.09 0.7632 0.6992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A14 mock treatment 432118.0 -7310.0 -0.04 479069.0 2990.0 0.02 -0.0187 -0.4012 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A15 compound treatment 393240.0 -46200.0 -0.27 528580.0 52500.0 0.3 0.0168 0.0413 3187738 PK04_108013 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A16 compound treatment 342082.0 -97300.0 -0.58 460493.0 -15600.0 -0.09 -0.4723 -0.8059 3071460 PK04_108014 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A17 compound treatment 460755.0 21300.0 0.13 496625.0 20500.0 0.12 0.1724 0.9991 3187739 PK04_108015 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A18 compound treatment 457382.0 18000.0 0.11 379356.0 -96700.0 -0.55 -0.3134 -0.5593 3071461 PK04_108016 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A19 compound treatment 481821.0 42400.0 0.25 474436.0 -1650.0 -0.01 0.1718 0.6804 3187740 PK04_108017 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A20 compound treatment 377969.0 -61500.0 -0.37 376445.0 -99600.0 -0.57 -0.6593 -0.9776 3071462 PK04_108018 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A21 compound treatment 444915.0 5490.0 0.03 499549.0 23500.0 0.13 0.1175 0.855 3187741 PK04_108019 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A22 compound treatment 194810.0 -245000.0 -1.46 139316.0 -337000.0 -1.92 -2.3836 -0.9908 3071463 PK04_108020 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A23 compound treatment 460151.0 20700.0 0.12 578107.0 102000.0 0.58 0.4975 0.8387 3187742 PK04_108021 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 A24 compound treatment 455247.0 15800.0 0.09 436988.0 -39100.0 -0.22 -0.0906 -0.3753 3071464 PK04_108022 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B01 compound treatment 440725.0 1300.0 0.01 584857.0 109000.0 0.62 0.4429 0.7159 2133065 PK04_108023 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B02 compound treatment 409925.0 -29500.0 -0.18 539383.0 63300.0 0.36 0.1304 0.3256 3071465 PK04_108024 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B03 compound treatment 485818.0 46400.0 0.28 518054.0 42000.0 0.24 0.364 0.9974 2133224 PK04_108025 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B04 compound treatment 496453.0 57000.0 0.34 449077.0 -27000.0 -0.15 0.1314 0.3527 1952196 PK04_108026 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B05 compound treatment 61939.0 -377000.0 -2.25 77051.0 -399000.0 -2.27 -3.1931 -1.0 2133510 PK04_108027 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B06 compound treatment 188040.0 -251000.0 -1.5 186541.0 -290000.0 -1.65 -2.2222 -0.9989 3071510 PK04_108028 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B07 compound treatment 521274.0 81900.0 0.49 456071.0 -20000.0 -0.11 0.264 0.5277 2128988 PK04_108029 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B08 compound treatment 372569.0 -66900.0 -0.4 336331.0 -140000.0 -0.79 -0.8433 -0.9488 3187870 PK04_108030 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B09 compound treatment 574156.0 135000.0 0.8 441055.0 -35000.0 -0.2 0.4261 0.5158 3187871 PK04_108031 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B10 compound treatment 478332.0 38900.0 0.23 416209.0 -59900.0 -0.34 -0.077 -0.187 3071511 PK04_108032 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B11 compound treatment 409270.0 -30200.0 -0.18 453597.0 -22500.0 -0.13 -0.2173 -0.9862 2129008 PK04_108033 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B12 compound treatment 468943.0 29500.0 0.18 468214.0 -7870.0 -0.04 0.0926 0.5107 3187872 PK04_108034 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B13 mock treatment 422902.0 -16500.0 -0.1 441928.0 -34200.0 -0.19 -0.2069 -0.9502 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B14 mock treatment 403317.0 -36100.0 -0.21 411849.0 -64200.0 -0.37 -0.4102 -0.968 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B15 compound treatment 353664.0 -85800.0 -0.51 357732.0 -118000.0 -0.67 -0.8368 -0.9907 3187873 PK04_108035 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CCC\C=C\CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B16 compound treatment 514212.0 74800.0 0.45 444085.0 -32000.0 -0.18 0.1861 0.387 3414061 PK04_108036 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B17 compound treatment 364730.0 -74700.0 -0.44 302833.0 -173000.0 -0.99 -1.011 -0.9354 3187874 PK04_108037 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B18 compound treatment 315811.0 -124000.0 -0.74 446212.0 -29900.0 -0.17 -0.6403 -0.8481 3071513 PK04_108038 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B19 compound treatment 401982.0 -37400.0 -0.22 423120.0 -53000.0 -0.3 -0.3705 -0.989 3187875 PK04_108039 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B20 compound treatment 334592.0 -105000.0 -0.62 283176.0 -193000.0 -1.1 -1.2169 -0.9642 3071514 PK04_108040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B21 compound treatment 315216.0 -124000.0 -0.74 424996.0 -51100.0 -0.29 -0.7281 -0.9167 3187876 PK04_108041 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B22 compound treatment 273797.0 -166000.0 -0.99 276926.0 -199000.0 -1.13 -1.4978 -0.9976 3071515 PK04_108042 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B23 compound treatment 508013.0 68600.0 0.41 609954.0 134000.0 0.76 0.827 0.9573 3187877 PK04_108043 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 B24 compound treatment 412186.0 -27200.0 -0.16 472835.0 -3250.0 -0.02 -0.1277 -0.7826 3071516 PK04_108044 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C01 compound treatment 518276.0 78900.0 0.47 589871.0 114000.0 0.65 0.7894 0.9876 3187878 PK04_108045 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C02 compound treatment 460193.0 20800.0 0.12 447348.0 -28700.0 -0.16 -0.0281 -0.1373 3071464 PK04_108046 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C03 compound treatment 527187.0 87800.0 0.52 574613.0 98500.0 0.56 0.7655 0.9994 3187879 PK04_108047 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C04 compound treatment 472145.0 32700.0 0.19 446520.0 -29600.0 -0.17 0.0188 0.0732 3071517 PK04_108048 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C05 compound treatment 519865.0 80400.0 0.48 448072.0 -28000.0 -0.16 0.2259 0.4477 3071518 PK04_108049 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C06 compound treatment 419500.0 -19900.0 -0.12 396396.0 -79700.0 -0.45 -0.4043 -0.8631 3187880 PK04_108050 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C07 compound treatment 458028.0 18600.0 0.11 498844.0 22800.0 0.13 0.1698 0.997 3187881 PK04_108051 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C08 compound treatment 67284.0 -372000.0 -2.21 68675.0 -407000.0 -2.32 -3.2043 -0.9997 3071519 PK04_108052 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C09 compound treatment 514501.0 75100.0 0.45 460773.0 -15300.0 -0.09 0.2544 0.5588 3187882 PK04_108053 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C10 compound treatment 225219.0 -214000.0 -1.27 198722.0 -277000.0 -1.58 -2.0167 -0.9944 3071520 PK04_108054 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C11 mock treatment 454099.0 14700.0 0.09 475489.0 -592.0 0.0 0.0594 0.6793 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C12 mock treatment 420910.0 -18500.0 -0.11 409810.0 -66300.0 -0.38 -0.3444 -0.8771 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C13 compound treatment 467356.0 27900.0 0.17 476796.0 715.0 0.0 0.1204 0.7242 3187883 PK04_108055 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C14 compound treatment 337876.0 -102000.0 -0.6 371577.0 -105000.0 -0.59 -0.8476 -1.0 3071521 PK04_108056 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C15 mock treatment 404798.0 -34600.0 -0.21 456504.0 -19600.0 -0.11 -0.2244 -0.9582 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C16 mock treatment 413168.0 -26300.0 -0.16 417539.0 -58500.0 -0.33 -0.3459 -0.9405 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C17 compound treatment 411651.0 -27800.0 -0.17 496279.0 20200.0 0.11 -0.0357 -0.1771 3188001 PK04_108057 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C18 compound treatment 460411.0 21000.0 0.12 442136.0 -33900.0 -0.19 -0.0482 -0.2095 3071522 PK04_108058 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C19 compound treatment 422907.0 -16500.0 -0.1 450954.0 -25100.0 -0.14 -0.1705 -0.9833 3188002 PK04_108059 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C20 compound treatment 61017.0 -378000.0 -2.25 61748.0 -414000.0 -2.36 -3.2585 -0.9997 3071523 PK04_108060 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C21 compound treatment 421589.0 -17800.0 -0.11 431437.0 -44600.0 -0.25 -0.2546 -0.9251 3188003 PK04_108061 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C22 compound treatment 67503.0 -372000.0 -2.21 69864.0 -406000.0 -2.31 -3.1986 -0.9998 3071524 PK04_108062 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C23 compound treatment 530083.0 90700.0 0.54 519117.0 43000.0 0.24 0.5546 0.936 3188004 PK04_108063 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 C24 compound treatment 554925.0 116000.0 0.69 532143.0 56100.0 0.32 0.7115 0.939 3071525 PK04_108064 CCOC(=O)C1OC[C@H](N1CC#C)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D01 compound treatment 256168.0 -183000.0 -1.09 342738.0 -133000.0 -0.76 -1.3074 -0.9842 3188005 PK04_108065 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D02 compound treatment 413701.0 -25700.0 -0.15 417501.0 -58600.0 -0.33 -0.3438 -0.9378 3414062 PK04_108066 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D03 compound treatment 237360.0 -202000.0 -1.2 273788.0 -202000.0 -1.15 -1.6638 -0.9998 3188006 PK04_108067 CC(C)C[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D04 compound treatment 416916.0 -22500.0 -0.13 443215.0 -32900.0 -0.19 -0.2269 -0.9867 3071527 PK04_108068 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D05 compound treatment 342840.0 -96600.0 -0.57 487815.0 11700.0 0.07 -0.3593 -0.6209 3188007 PK04_108069 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D06 compound treatment 108974.0 -330000.0 -1.97 113608.0 -362000.0 -2.06 -2.8482 -0.9997 3071528 PK04_108070 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D07 compound treatment 427968.0 -11500.0 -0.07 455359.0 -20700.0 -0.12 -0.1315 -0.9662 3188008 PK04_108071 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D08 compound treatment 445774.0 6350.0 0.04 470648.0 -5430.0 -0.03 0.0049 0.0999 3071529 PK04_108072 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D09 compound treatment 443301.0 3880.0 0.02 503031.0 26900.0 0.15 0.1247 0.8045 3188009 PK04_108073 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)CNC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D10 compound treatment 424139.0 -15300.0 -0.09 408257.0 -67800.0 -0.39 -0.3371 -0.8505 3071530 PK04_108074 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D11 mock treatment 408267.0 -31200.0 -0.19 305094.0 -171000.0 -0.97 -0.8187 -0.827 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D12 mock treatment 413082.0 -26300.0 -0.16 418165.0 -57900.0 -0.33 -0.3437 -0.9424 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D13 compound treatment 411446.0 -28000.0 -0.17 433650.0 -42400.0 -0.24 -0.2884 -0.9836 3188010 PK04_108075 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D14 compound treatment 106876.0 -333000.0 -1.98 100221.0 -376000.0 -2.14 -2.9108 -0.9993 3071531 PK04_108076 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D15 mock treatment 497365.0 57900.0 0.34 448627.0 -27500.0 -0.16 0.1334 0.3525 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D16 mock treatment 433936.0 -5490.0 -0.03 476236.0 155.0 0.0 -0.0225 -0.6878 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D17 compound treatment 318474.0 -121000.0 -0.72 333435.0 -143000.0 -0.81 -1.0826 -0.9982 3071578 PK04_108077 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D18 compound treatment 65714.0 -374000.0 -2.22 72132.0 -404000.0 -2.3 -3.197 -0.9999 3071579 PK04_108078 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D19 compound treatment 306127.0 -133000.0 -0.79 262108.0 -214000.0 -1.22 -1.4214 -0.9785 3071580 PK04_108079 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc6ccccc6)NC2=O)[C@@H]7O[C@]7(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D20 compound treatment 62536.0 -377000.0 -2.24 67624.0 -408000.0 -2.32 -3.2285 -0.9998 3188011 PK04_108080 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D21 compound treatment 406577.0 -32800.0 -0.2 400644.0 -75400.0 -0.43 -0.4416 -0.9367 3188012 PK04_108081 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D22 compound treatment 158118.0 -281000.0 -1.67 142529.0 -334000.0 -1.9 -2.5251 -0.9981 3071581 PK04_108082 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D23 compound treatment 443222.0 3800.0 0.02 478634.0 2550.0 0.01 0.0263 0.9771 3188013 PK04_108083 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 D24 compound treatment 138596.0 -301000.0 -1.79 143093.0 -333000.0 -1.89 -2.605 -0.9996 3071582 PK04_108084 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E01 mock treatment 477656.0 38200.0 0.23 475372.0 -709.0 0.0 0.158 0.6945 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E02 mock treatment 433938.0 -5490.0 -0.03 485070.0 8990.0 0.05 0.0131 0.2153 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E03 compound treatment 444508.0 5080.0 0.03 475264.0 -817.0 0.0 0.0181 0.5916 3188014 PK04_108085 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E04 compound treatment 81608.0 -358000.0 -2.13 86276.0 -390000.0 -2.22 -3.0733 -0.9998 3071583 PK04_108086 C/C=C/CN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E05 compound treatment 458577.0 19200.0 0.11 474254.0 -1830.0 -0.01 0.0733 0.64 3188015 PK04_108087 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E06 compound treatment 405001.0 -34400.0 -0.2 438715.0 -37400.0 -0.21 -0.2951 -0.9998 3071584 PK04_108088 OCC(NCC#C)/C=C/c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E07 compound treatment 444844.0 5420.0 0.03 425683.0 -50400.0 -0.29 -0.1798 -0.6236 3188129 PK04_108089 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E08 compound treatment 392929.0 -46500.0 -0.28 433227.0 -42900.0 -0.24 -0.368 -0.998 3071585 PK04_108090 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E09 mock treatment 419783.0 -19600.0 -0.12 456435.0 -19600.0 -0.11 -0.1617 -0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E10 mock treatment 459445.0 20000.0 0.12 460906.0 -15200.0 -0.09 0.0232 0.1579 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E11 compound treatment 426728.0 -12700.0 -0.08 449131.0 -27000.0 -0.15 -0.1618 -0.9469 3071586 PK04_108091 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E12 compound treatment 326375.0 -113000.0 -0.67 335284.0 -141000.0 -0.8 -1.0419 -0.9963 3188130 PK04_108092 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E13 compound treatment 466022.0 26600.0 0.16 433101.0 -43000.0 -0.24 -0.0609 -0.2091 3188131 PK04_108093 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E14 compound treatment 352907.0 -86500.0 -0.51 386862.0 -89200.0 -0.51 -0.7228 -1.0 3071587 PK04_108094 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E15 compound treatment 406009.0 -33400.0 -0.2 437711.0 -38400.0 -0.22 -0.2949 -0.9989 3188132 PK04_108095 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E16 compound treatment 96065.0 -343000.0 -2.04 100991.0 -375000.0 -2.13 -2.9532 -0.9998 3071588 PK04_108096 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E17 mock treatment 408766.0 -30700.0 -0.18 449906.0 -26200.0 -0.15 -0.2343 -0.9949 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E18 mock treatment 446956.0 7530.0 0.04 480688.0 4610.0 0.03 0.0502 0.9673 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E19 compound treatment 395230.0 -44200.0 -0.26 446181.0 -29900.0 -0.17 -0.3062 -0.9777 3188133 PK04_108097 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E20 compound treatment 77987.0 -361000.0 -2.15 73069.0 -403000.0 -2.29 -3.1416 -0.9995 3071589 PK04_108098 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E21 compound treatment 461362.0 21900.0 0.13 463699.0 -12400.0 -0.07 0.0425 0.2867 3188134 PK04_108099 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E22 compound treatment 124758.0 -315000.0 -1.87 121294.0 -355000.0 -2.02 -2.7509 -0.9993 3071590 PK04_108100 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E23 compound treatment 422429.0 -17000.0 -0.1 393847.0 -82200.0 -0.47 -0.4022 -0.8406 3188135 PK04_108101 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 E24 compound treatment 177666.0 -262000.0 -1.56 168012.0 -308000.0 -1.75 -2.3403 -0.9983 3071591 PK04_108102 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F01 mock treatment 440012.0 589.0 0.0 506778.0 30700.0 0.17 0.1259 0.7212 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F02 mock treatment 490174.0 50800.0 0.3 454745.0 -21300.0 -0.12 0.1278 0.3926 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F03 compound treatment 451214.0 11800.0 0.07 412274.0 -63800.0 -0.36 -0.207 -0.56 3188136 PK04_108103 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F04 compound treatment 465438.0 26000.0 0.15 520566.0 44500.0 0.25 0.2884 0.9722 3071592 PK04_108104 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F05 compound treatment 460862.0 21400.0 0.13 553368.0 77300.0 0.44 0.401 0.8762 3188137 PK04_108105 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F06 compound treatment 517998.0 78600.0 0.47 515610.0 39500.0 0.22 0.4896 0.9436 3071592 PK04_108106 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F07 compound treatment 444497.0 5070.0 0.03 578715.0 103000.0 0.58 0.4341 0.7427 3071593 PK04_108107 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F08 compound treatment 67160.0 -372000.0 -2.22 68422.0 -408000.0 -2.32 -3.2058 -0.9997 3188138 PK04_108108 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F09 mock treatment 398652.0 -40800.0 -0.24 500566.0 24500.0 0.14 -0.0731 -0.2614 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F10 mock treatment 400106.0 -39300.0 -0.23 453992.0 -22100.0 -0.13 -0.2543 -0.9575 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F11 compound treatment 407159.0 -32300.0 -0.19 477879.0 1800.0 0.01 -0.1285 -0.6685 3188139 PK04_108109 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F12 compound treatment 487406.0 48000.0 0.29 458744.0 -17300.0 -0.1 0.1322 0.4376 3071594 PK04_108110 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F13 compound treatment 472046.0 32600.0 0.19 448264.0 -27800.0 -0.16 0.0254 0.1015 3188140 PK04_108111 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F14 compound treatment 466548.0 27100.0 0.16 464375.0 -11700.0 -0.07 0.0671 0.3841 3414064 PK04_108112 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F15 compound treatment 435504.0 -3920.0 -0.02 525045.0 49000.0 0.28 0.1804 0.6456 3071596 PK04_108113 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F16 compound treatment 384247.0 -55200.0 -0.33 436501.0 -39600.0 -0.23 -0.3914 -0.983 3188141 PK04_108114 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F17 mock treatment 398580.0 -40800.0 -0.24 481597.0 5520.0 0.03 -0.1497 -0.6108 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F18 mock treatment 430437.0 -8990.0 -0.05 500076.0 24000.0 0.14 0.0587 0.4003 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F19 compound treatment 454314.0 14900.0 0.09 448129.0 -28000.0 -0.16 -0.0497 -0.2733 3188142 PK04_108115 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F20 compound treatment 78973.0 -360000.0 -2.15 73287.0 -403000.0 -2.29 -3.1366 -0.9995 3071597 PK04_108116 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F21 compound treatment 426670.0 -12800.0 -0.08 470158.0 -5920.0 -0.03 -0.0775 -0.9331 3188143 PK04_108117 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F22 compound treatment 319772.0 -120000.0 -0.71 283722.0 -192000.0 -1.09 -1.277 -0.9784 3071598 PK04_108118 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F23 compound treatment 452999.0 13600.0 0.08 438680.0 -37400.0 -0.21 -0.0933 -0.4099 3188144 PK04_108119 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@@H](C)NC4=O)[C@@H]5O[C@@]51C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 F24 compound treatment 66948.0 -372000.0 -2.22 67873.0 -408000.0 -2.32 -3.2089 -0.9997 3188260 PK04_108120 CC(=O)O[C@@H]([C@@H]1CCCN1S(=O)(=O)c2ccccc2[N+](=O)[O-])C(=C)C3=CCN(C3)S(=O)(=O)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G01 compound treatment 430921.0 -8500.0 -0.05 417704.0 -58400.0 -0.33 -0.2705 -0.8056 3071599 PK04_108121 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G02 compound treatment 167070.0 -272000.0 -1.62 224809.0 -251000.0 -1.43 -2.1565 -0.998 3188261 PK04_108122 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G03 mock treatment 454956.0 15500.0 0.09 448091.0 -28000.0 -0.16 -0.0472 -0.2564 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G04 mock treatment 426302.0 -13100.0 -0.08 484319.0 8240.0 0.05 -0.0221 -0.2426 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G05 compound treatment 422275.0 -17100.0 -0.1 462187.0 -13900.0 -0.08 -0.128 -0.992 3188262 PK04_108123 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G06 compound treatment 218426.0 -221000.0 -1.32 185219.0 -291000.0 -1.65 -2.0996 -0.9936 3071600 PK04_108124 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G07 compound treatment 444885.0 5460.0 0.03 462472.0 -13600.0 -0.08 -0.0317 -0.3781 3189036 PK04_108125 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G08 compound treatment 422217.0 -17200.0 -0.1 349384.0 -127000.0 -0.72 -0.5819 -0.7996 3071601 PK04_108126 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G09 compound treatment 481575.0 42200.0 0.25 445733.0 -30300.0 -0.17 0.0554 0.1818 3188263 PK04_108127 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G10 compound treatment 297988.0 -141000.0 -0.84 320887.0 -155000.0 -0.88 -1.2193 -0.9997 3071602 PK04_108128 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G11 compound treatment 467389.0 28000.0 0.17 522938.0 46900.0 0.27 0.3061 0.9743 3188264 PK04_108129 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G12 compound treatment 372925.0 -66500.0 -0.4 361817.0 -114000.0 -0.65 -0.7393 -0.9717 3071603 PK04_108130 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G13 compound treatment 460312.0 20900.0 0.12 467687.0 -8390.0 -0.05 0.0542 0.4066 3188265 PK04_108131 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G14 compound treatment 265263.0 -174000.0 -1.04 165420.0 -311000.0 -1.77 -1.9821 -0.9677 3071604 PK04_108132 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G15 compound treatment 413225.0 -26200.0 -0.16 373185.0 -103000.0 -0.59 -0.524 -0.8653 3188266 PK04_108133 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G16 compound treatment 74267.0 -365000.0 -2.17 68062.0 -408000.0 -2.32 -3.1774 -0.9995 3071651 PK04_108134 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G17 compound treatment 157053.0 -282000.0 -1.68 393378.0 -82700.0 -0.47 -1.5209 -0.8715 3188267 PK04_108135 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G18 compound treatment 68884.0 -371000.0 -2.21 70554.0 -406000.0 -2.31 -3.19 -0.9997 3071652 PK04_108136 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G19 mock treatment 433800.0 -5620.0 -0.03 442744.0 -33300.0 -0.19 -0.1577 -0.8193 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G20 mock treatment 428347.0 -11100.0 -0.07 300600.0 -175000.0 -1.0 -0.7522 -0.7522 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G21 compound treatment 483203.0 43800.0 0.26 473824.0 -2260.0 -0.01 0.1752 0.6715 3189164 PK04_108137 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G22 compound treatment 67132.0 -372000.0 -2.22 61215.0 -415000.0 -2.36 -3.2349 -0.9995 3071653 PK04_108138 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G23 compound treatment 495996.0 56600.0 0.34 471147.0 -4930.0 -0.03 0.2182 0.6459 3189167 PK04_108139 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 G24 compound treatment 387537.0 -51900.0 -0.31 282531.0 -194000.0 -1.1 -0.9966 -0.8718 3188268 PK04_108140 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H01 compound treatment 518629.0 79200.0 0.47 582550.0 106000.0 0.61 0.7614 0.9923 3188269 PK04_108141 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H02 compound treatment 139061.0 -300000.0 -1.79 370304.0 -106000.0 -0.6 -1.6894 -0.8957 3071654 PK04_108142 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H03 mock treatment 246289.0 -193000.0 -1.15 445374.0 -30700.0 -0.17 -0.9362 -0.8053 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H04 mock treatment 258112.0 -181000.0 -1.08 441928.0 -34200.0 -0.19 -0.9003 -0.8212 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H05 compound treatment 453959.0 14500.0 0.09 474926.0 -1160.0 -0.01 0.0565 0.6515 3188270 PK04_108143 CC(C)C[C@@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H06 compound treatment 384906.0 -54500.0 -0.32 444856.0 -31200.0 -0.18 -0.355 -0.9598 3071655 PK04_108144 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H07 compound treatment 427940.0 -11500.0 -0.07 462871.0 -13200.0 -0.08 -0.1014 -0.9989 3188271 PK04_108145 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H08 compound treatment 64745.0 -375000.0 -2.23 43918.0 -432000.0 -2.46 -3.3145 -0.9988 3071656 PK04_108146 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H09 compound treatment 381219.0 -58200.0 -0.35 304227.0 -172000.0 -0.98 -0.936 -0.9027 3188272 PK04_108147 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H10 compound treatment 65215.0 -374000.0 -2.23 67907.0 -408000.0 -2.32 -3.2161 -0.9998 3071529 PK04_108148 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H11 compound treatment 418428.0 -21000.0 -0.12 409609.0 -66500.0 -0.38 -0.3556 -0.8933 3188273 PK04_108149 CC(C)C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC1=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H12 compound treatment 394404.0 -45000.0 -0.27 472551.0 -3530.0 -0.02 -0.2036 -0.758 3071527 PK04_108150 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H13 compound treatment 385480.0 -53900.0 -0.32 468980.0 -7100.0 -0.04 -0.2556 -0.7898 3071658 PK04_108151 CC(C)C[C@H]1NC(=O)[C@@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H14 compound treatment 105553.0 -334000.0 -1.99 104792.0 -371000.0 -2.11 -2.898 -0.9995 3188274 PK04_108152 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H15 compound treatment 455210.0 15800.0 0.09 370060.0 -106000.0 -0.6 -0.3599 -0.5898 3188275 PK04_108153 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H16 compound treatment 310468.0 -129000.0 -0.77 235457.0 -241000.0 -1.37 -1.5103 -0.9626 3071661 PK04_108154 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H17 compound treatment 421135.0 -18300.0 -0.11 358686.0 -117000.0 -0.67 -0.549 -0.8117 3188391 PK04_108155 CC(C)C[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H18 compound treatment 66929.0 -372000.0 -2.22 66055.0 -410000.0 -2.33 -3.2163 -0.9997 3071664 PK04_108156 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H19 mock treatment 467849.0 28400.0 0.17 538451.0 62400.0 0.35 0.3704 0.9426 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H20 mock treatment 449502.0 10100.0 0.06 483062.0 6980.0 0.04 0.0705 0.9799 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H21 compound treatment 472687.0 33300.0 0.2 481762.0 5680.0 0.03 0.1628 0.8118 3188392 PK04_108157 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H22 compound treatment 429597.0 -9830.0 -0.06 349330.0 -127000.0 -0.72 -0.551 -0.762 3071666 PK04_108158 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H23 compound treatment 397089.0 -42300.0 -0.25 243709.0 -232000.0 -1.32 -1.1126 -0.827 3188393 PK04_108159 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H]6CCCN6C2=O)[C@@H]7O[C@]7(C)[C@H]4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 H24 compound treatment 502952.0 63500.0 0.38 510422.0 34300.0 0.2 0.4054 0.9528 3071711 PK04_108160 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I01 compound treatment 561013.0 122000.0 0.72 472458.0 -3620.0 -0.02 0.4971 0.6867 3188394 PK04_108161 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I02 compound treatment 203361.0 -236000.0 -1.4 171229.0 -305000.0 -1.73 -2.2193 -0.9946 3071714 PK04_108162 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I03 compound treatment 519998.0 80600.0 0.48 153810.0 -322000.0 -1.83 -0.9568 -0.5051 3188395 PK04_108163 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I04 compound treatment 105340.0 -334000.0 -1.99 220492.0 -256000.0 -1.45 -2.4337 -0.9881 3071715 PK04_108164 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I05 mock treatment 441531.0 2110.0 0.01 106491.0 -370000.0 -2.1 -1.4773 -0.7029 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I06 mock treatment 407040.0 -32400.0 -0.19 190222.0 -286000.0 -1.63 -1.2858 -0.7854 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I07 compound treatment 502315.0 62900.0 0.37 510299.0 34200.0 0.19 0.4023 0.9536 3188396 PK04_108165 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I08 compound treatment 187136.0 -252000.0 -1.5 66019.0 -410000.0 -2.33 -2.7106 -0.9773 3071717 PK04_108166 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I09 compound treatment 276519.0 -163000.0 -0.97 462145.0 -13900.0 -0.08 -0.7416 -0.7624 3188397 PK04_108167 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I10 compound treatment 252294.0 -187000.0 -1.11 106587.0 -369000.0 -2.1 -2.2733 -0.9559 3071720 PK04_108168 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I11 compound treatment 407337.0 -32100.0 -0.19 180817.0 -295000.0 -1.68 -1.3223 -0.7825 3188398 PK04_108169 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I12 compound treatment 68894.0 -371000.0 -2.21 76006.0 -400000.0 -2.28 -3.1681 -0.9999 3071724 PK04_108170 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I13 compound treatment 365256.0 -74200.0 -0.44 134030.0 -342000.0 -1.95 -1.6876 -0.8461 3071725 PK04_108171 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I14 compound treatment 368529.0 -70900.0 -0.42 115059.0 -361000.0 -2.05 -1.7501 -0.835 3071727 PK04_108172 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I15 compound treatment 65783.0 -374000.0 -2.22 51949.0 -424000.0 -2.41 -3.2779 -0.9992 3188399 PK04_108173 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I16 compound treatment 123508.0 -316000.0 -1.88 109150.0 -367000.0 -2.09 -2.8049 -0.9986 3071766 PK04_108174 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I17 compound treatment 147108.0 -292000.0 -1.74 210926.0 -265000.0 -1.51 -2.2964 -0.9975 3188400 PK04_108175 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I18 compound treatment 465344.0 25900.0 0.15 391927.0 -84200.0 -0.48 -0.2293 -0.4561 3071767 PK04_108176 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I19 compound treatment 64794.0 -375000.0 -2.23 66394.0 -410000.0 -2.33 -3.224 -0.9998 3188401 PK04_108177 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I20 compound treatment 322155.0 -117000.0 -0.7 129751.0 -346000.0 -1.97 -1.8861 -0.9027 3071770 PK04_108178 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I21 mock treatment 433370.0 -6050.0 -0.04 517499.0 41400.0 0.24 0.1411 0.5921 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I22 mock treatment 427245.0 -12200.0 -0.07 186224.0 -290000.0 -1.65 -1.2168 -0.7375 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I23 compound treatment 319544.0 -120000.0 -0.71 196910.0 -279000.0 -1.59 -1.6271 -0.9348 3188402 PK04_108179 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 I24 compound treatment 68749.0 -371000.0 -2.21 77697.0 -398000.0 -2.27 -3.1619 -0.9999 3071774 PK04_108180 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J01 compound treatment 474795.0 35400.0 0.21 454616.0 -21500.0 -0.12 0.0625 0.257 3188403 PK04_108181 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J02 compound treatment 352958.0 -86500.0 -0.51 296188.0 -180000.0 -1.02 -1.0872 -0.9494 3071776 PK04_108182 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J03 compound treatment 245180.0 -194000.0 -1.16 281591.0 -194000.0 -1.11 -1.5995 -0.9998 3188404 PK04_108183 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J04 compound treatment 271189.0 -168000.0 -1.0 124481.0 -352000.0 -2.0 -2.1218 -0.9489 3188405 PK04_108184 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J05 mock treatment 223286.0 -216000.0 -1.29 404780.0 -71300.0 -0.41 -1.1963 -0.887 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J06 mock treatment 440555.0 1130.0 0.01 450783.0 -25300.0 -0.14 -0.097 -0.6733 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J07 compound treatment 525400.0 86000.0 0.51 478167.0 2090.0 0.01 0.3702 0.7233 3070928 PK04_108185 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J08 compound treatment 438192.0 -1230.0 -0.01 441204.0 -34900.0 -0.2 -0.1454 -0.7327 3070929 PK04_108186 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J09 compound treatment 283594.0 -156000.0 -0.93 479657.0 3580.0 0.02 -0.6414 -0.6914 3070930 PK04_108187 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J10 compound treatment 145123.0 -294000.0 -1.75 209219.0 -267000.0 -1.52 -2.3116 -0.9974 3188406 PK04_108188 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J11 compound treatment 161022.0 -278000.0 -1.66 417496.0 -58600.0 -0.33 -1.4072 -0.8326 3188407 PK04_108189 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J12 compound treatment 113033.0 -326000.0 -1.94 253753.0 -222000.0 -1.26 -2.2676 -0.9784 3070931 PK04_108190 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J13 compound treatment 409285.0 -30100.0 -0.18 240721.0 -235000.0 -1.34 -1.0732 -0.7948 3070932 PK04_108191 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J14 compound treatment 370173.0 -69300.0 -0.41 215170.0 -261000.0 -1.48 -1.3406 -0.8706 3070933 PK04_108192 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J15 compound treatment 106425.0 -333000.0 -1.98 58646.0 -417000.0 -2.37 -3.0799 -0.996 3188522 PK04_108193 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J16 compound treatment 392719.0 -46700.0 -0.28 162821.0 -313000.0 -1.78 -1.4562 -0.8077 3188523 PK04_108194 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J17 compound treatment 434531.0 -4890.0 -0.03 506295.0 30200.0 0.17 0.1009 0.579 3070934 PK04_108195 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J18 compound treatment 447940.0 8520.0 0.05 534639.0 58600.0 0.33 0.2713 0.8055 3188524 PK04_108196 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J19 compound treatment 404875.0 -34500.0 -0.21 345907.0 -130000.0 -0.74 -0.6688 -0.8706 3070935 PK04_108197 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J20 compound treatment 447522.0 8100.0 0.05 464543.0 -11500.0 -0.07 -0.0123 -0.1513 3188525 PK04_108198 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J21 mock treatment 458582.0 19200.0 0.11 498008.0 21900.0 0.12 0.1688 0.999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J22 mock treatment 402440.0 -37000.0 -0.22 201671.0 -274000.0 -1.56 -1.2591 -0.7989 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J23 compound treatment 501048.0 61600.0 0.37 530072.0 54000.0 0.31 0.4764 0.9961 3070936 PK04_108199 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 J24 compound treatment 407899.0 -31500.0 -0.19 486866.0 10800.0 0.06 -0.0893 -0.4524 3188526 PK04_108200 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K01 compound treatment 79711.0 -360000.0 -2.14 76646.0 -399000.0 -2.27 -3.12 -0.9996 3070937 PK04_108201 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K02 compound treatment 74657.0 -365000.0 -2.17 30897.0 -445000.0 -2.53 -3.3252 -0.9971 3188527 PK04_108202 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K03 compound treatment 95412.0 -344000.0 -2.05 55550.0 -421000.0 -2.39 -3.1387 -0.997 3188528 PK04_108203 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K04 compound treatment 76038.0 -363000.0 -2.16 26775.0 -449000.0 -2.56 -3.336 -0.9966 3070938 PK04_108204 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K05 compound treatment 498783.0 59400.0 0.35 262776.0 -213000.0 -1.21 -0.6079 -0.4812 3188529 PK04_108205 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K06 compound treatment 74916.0 -365000.0 -2.17 73598.0 -402000.0 -2.29 -3.1524 -0.9996 3070939 PK04_108206 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K07 mock treatment 461845.0 22400.0 0.13 232035.0 -244000.0 -1.39 -0.887 -0.6362 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K08 mock treatment 422878.0 -16500.0 -0.1 336525.0 -140000.0 -0.79 -0.6308 -0.7888 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K09 compound treatment 79596.0 -360000.0 -2.14 77077.0 -399000.0 -2.27 -3.1187 -0.9996 3188530 PK04_108207 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K10 compound treatment 52866.0 -387000.0 -2.3 27117.0 -449000.0 -2.55 -3.4321 -0.9986 3188531 PK04_108208 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K11 compound treatment 65213.0 -374000.0 -2.23 26002.0 -450000.0 -2.56 -3.3846 -0.9976 3070940 PK04_108209 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K12 compound treatment 243366.0 -196000.0 -1.17 84579.0 -392000.0 -2.23 -2.3994 -0.9545 3188532 PK04_108210 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K13 compound treatment 30835.0 -409000.0 -2.43 244847.0 -231000.0 -1.31 -2.6493 -0.9583 3188533 PK04_108211 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K14 compound treatment 46971.0 -392000.0 -2.34 34704.0 -441000.0 -2.51 -3.4264 -0.9994 3070941 PK04_108212 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K15 mock treatment 268564.0 -171000.0 -1.02 499653.0 23600.0 0.13 -0.6242 -0.6086 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K16 mock treatment 519844.0 80400.0 0.48 503641.0 27600.0 0.16 0.4493 0.892 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K17 compound treatment 83080.0 -356000.0 -2.12 73209.0 -403000.0 -2.29 -3.1196 -0.9993 3188534 PK04_108213 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K18 compound treatment 380733.0 -58700.0 -0.35 253097.0 -223000.0 -1.27 -1.1436 -0.8695 3070942 PK04_108214 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K19 compound treatment 217745.0 -222000.0 -1.32 161297.0 -315000.0 -1.79 -2.1987 -0.9887 3188535 PK04_108215 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K20 compound treatment 495895.0 56500.0 0.34 437919.0 -38200.0 -0.22 0.0842 0.2104 3070943 PK04_108216 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K21 compound treatment 274913.0 -165000.0 -0.98 150530.0 -326000.0 -1.85 -2.0014 -0.9556 3188536 PK04_108217 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K22 compound treatment 288818.0 -151000.0 -0.9 326017.0 -150000.0 -0.85 -1.2372 -0.9997 3188537 PK04_108218 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K23 mock treatment 457138.0 17700.0 0.11 476644.0 563.0 0.0 0.0768 0.7282 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 K24 mock treatment 438387.0 -1040.0 -0.01 462545.0 -13500.0 -0.08 -0.0588 -0.7613 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L01 compound treatment 493937.0 54500.0 0.32 224789.0 -251000.0 -1.43 -0.7811 -0.533 3070944 PK04_108219 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L02 compound treatment 501569.0 62100.0 0.37 327163.0 -149000.0 -0.85 -0.3373 -0.365 3188538 PK04_108220 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L03 compound treatment 474962.0 35500.0 0.21 90543.0 -386000.0 -2.19 -1.4007 -0.6359 3188539 PK04_108221 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L04 compound treatment 442676.0 3250.0 0.02 183361.0 -293000.0 -1.66 -1.1634 -0.6988 3215882 PK04_108222 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L05 compound treatment 497578.0 58200.0 0.35 566298.0 90200.0 0.51 0.6075 0.9816 3188540 PK04_108223 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L06 compound treatment 394610.0 -44800.0 -0.27 471773.0 -4310.0 -0.02 -0.2059 -0.7688 3215880 PK04_108224 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L07 mock treatment 494992.0 55600.0 0.33 164943.0 -311000.0 -1.77 -1.0173 -0.5652 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L08 mock treatment 445655.0 6230.0 0.04 386449.0 -89600.0 -0.51 -0.3342 -0.6539 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L09 compound treatment 481833.0 42400.0 0.25 268785.0 -207000.0 -1.18 -0.6551 -0.5434 3188541 PK04_108225 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L10 compound treatment 66969.0 -372000.0 -2.22 24593.0 -451000.0 -2.57 -3.3829 -0.9973 3188542 PK04_108226 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L11 compound treatment 75263.0 -364000.0 -2.17 33390.0 -443000.0 -2.52 -3.3126 -0.9972 3070947 PK04_108227 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L12 compound treatment 70320.0 -369000.0 -2.2 17322.0 -459000.0 -2.61 -3.398 -0.9963 3188543 PK04_108228 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L13 compound treatment 160298.0 -279000.0 -1.66 90920.0 -385000.0 -2.19 -2.7234 -0.9907 3188544 PK04_108229 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L14 compound treatment 64914.0 -375000.0 -2.23 68317.0 -408000.0 -2.32 -3.2157 -0.9998 3070948 PK04_108230 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L15 mock treatment 470346.0 30900.0 0.18 460325.0 -15800.0 -0.09 0.0668 0.3262 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L16 mock treatment 492499.0 53100.0 0.32 170113.0 -306000.0 -1.74 -1.007 -0.5694 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L17 compound treatment 368264.0 -71200.0 -0.42 461873.0 -14200.0 -0.08 -0.3566 -0.8271 3188657 PK04_108231 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L18 compound treatment 61154.0 -378000.0 -2.25 39699.0 -436000.0 -2.48 -3.3466 -0.9988 3070949 PK04_108232 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L19 compound treatment 400952.0 -38500.0 -0.23 395346.0 -80700.0 -0.46 -0.4865 -0.9484 3188658 PK04_108233 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L20 compound treatment 59675.0 -380000.0 -2.26 64913.0 -411000.0 -2.34 -3.2515 -0.9999 3070950 PK04_108234 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L21 compound treatment 425760.0 -13700.0 -0.08 304212.0 -172000.0 -0.98 -0.7486 -0.7633 3188659 PK04_108235 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L22 compound treatment 57117.0 -382000.0 -2.28 63983.0 -412000.0 -2.34 -3.266 -0.9999 3070951 PK04_108236 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L23 mock treatment 481485.0 42100.0 0.25 554057.0 78000.0 0.44 0.4906 0.9634 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 L24 mock treatment 449799.0 10400.0 0.06 546688.0 70600.0 0.4 0.3276 0.8064 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M01 compound treatment 436478.0 -2950.0 -0.02 523968.0 47900.0 0.27 0.1802 0.6602 3188660 PK04_108237 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M02 compound treatment 79816.0 -360000.0 -2.14 68413.0 -408000.0 -2.32 -3.1526 -0.9992 3070952 PK04_108238 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M03 compound treatment 254031.0 -185000.0 -1.1 372706.0 -103000.0 -0.59 -1.1959 -0.9566 3188661 PK04_108239 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M04 compound treatment 69424.0 -370000.0 -2.2 72532.0 -404000.0 -2.29 -3.1798 -0.9998 3070953 PK04_108240 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M05 compound treatment 70098.0 -369000.0 -2.2 65033.0 -411000.0 -2.34 -3.2071 -0.9995 3188662 PK04_108241 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M06 compound treatment 74185.0 -365000.0 -2.17 75854.0 -400000.0 -2.28 -3.1464 -0.9997 3070954 PK04_108242 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M07 compound treatment 76051.0 -363000.0 -2.16 101513.0 -375000.0 -2.13 -3.0354 -1.0 3188663 PK04_108243 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M08 compound treatment 77791.0 -362000.0 -2.15 80530.0 -396000.0 -2.25 -3.1124 -0.9998 3188664 PK04_108244 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M09 mock treatment 517338.0 77900.0 0.46 499546.0 23500.0 0.13 0.4222 0.8751 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M10 mock treatment 507100.0 67700.0 0.4 585548.0 109000.0 0.62 0.725 0.9778 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M11 compound treatment 486547.0 47100.0 0.28 523869.0 47800.0 0.27 0.3905 0.9999 3070955 PK04_108245 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M12 compound treatment 134615.0 -305000.0 -1.81 153586.0 -322000.0 -1.83 -2.5795 -1.0 3188665 PK04_108246 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M13 mock treatment 493968.0 54500.0 0.32 553051.0 77000.0 0.44 0.539 0.9892 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M14 mock treatment 485994.0 46600.0 0.28 531889.0 55800.0 0.32 0.4204 0.9977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M15 compound treatment 528378.0 89000.0 0.53 476991.0 910.0 0.01 0.378 0.714 3188666 PK04_108247 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M16 compound treatment 268725.0 -171000.0 -1.02 306463.0 -170000.0 -0.96 -1.4004 -0.9997 3070994 PK04_108248 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M17 compound treatment 412991.0 -26400.0 -0.16 507335.0 31300.0 0.18 0.0144 0.0608 3188667 PK04_108249 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M18 compound treatment 434711.0 -4710.0 -0.03 570842.0 94800.0 0.54 0.3612 0.6694 3070995 PK04_108250 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M19 compound treatment 394168.0 -45300.0 -0.27 467091.0 -8990.0 -0.05 -0.2266 -0.8266 3188668 PK04_108251 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M20 compound treatment 428245.0 -11200.0 -0.07 521295.0 45200.0 0.26 0.1348 0.5074 2133134 PK04_108252 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M21 compound treatment 251957.0 -187000.0 -1.12 266871.0 -209000.0 -1.19 -1.6302 -0.9995 3070996 PK04_108253 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M22 compound treatment 507489.0 68100.0 0.41 555219.0 79100.0 0.45 0.6047 0.9986 2133147 PK04_108254 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M23 compound treatment 481354.0 41900.0 0.25 570944.0 94900.0 0.54 0.5579 0.9386 3070997 PK04_108255 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 M24 compound treatment 356580.0 -82800.0 -0.49 393644.0 -82400.0 -0.47 -0.6801 -0.9997 3188671 PK04_108256 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N01 compound treatment 416771.0 -22700.0 -0.13 441474.0 -34600.0 -0.2 -0.2345 -0.983 3188672 PK04_108257 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N02 compound treatment 430274.0 -9150.0 -0.05 481619.0 5540.0 0.03 -0.0162 -0.2581 3070998 PK04_108258 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N03 compound treatment 434274.0 -5150.0 -0.03 514887.0 38800.0 0.22 0.1344 0.6031 3188673 PK04_108259 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N04 compound treatment 522245.0 82800.0 0.49 493379.0 17300.0 0.1 0.4181 0.8318 3070999 PK04_108260 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N05 compound treatment 285119.0 -154000.0 -0.92 548690.0 72600.0 0.41 -0.3574 -0.3549 3188674 PK04_108261 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N06 compound treatment 60901.0 -379000.0 -2.25 70048.0 -406000.0 -2.31 -3.2256 -0.9999 3071000 PK04_108262 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N07 compound treatment 527764.0 88300.0 0.53 561070.0 85000.0 0.48 0.7135 0.9991 3188675 PK04_108263 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N08 compound treatment 367418.0 -72000.0 -0.43 534053.0 58000.0 0.33 -0.0699 -0.1293 3188676 PK04_108264 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N09 mock treatment 522700.0 83300.0 0.5 590505.0 114000.0 0.65 0.8106 0.991 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N10 mock treatment 518189.0 78800.0 0.47 524673.0 48600.0 0.28 0.5269 0.9682 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N11 compound treatment 305595.0 -134000.0 -0.8 294299.0 -182000.0 -1.03 -1.2942 -0.9917 3071001 PK04_108265 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N12 compound treatment 525265.0 85800.0 0.51 606759.0 131000.0 0.74 0.8867 0.9833 3188677 PK04_108266 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N13 mock treatment 491715.0 52300.0 0.31 510731.0 34600.0 0.2 0.3594 0.9757 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N14 mock treatment 463779.0 24400.0 0.14 505129.0 29000.0 0.17 0.2193 0.9979 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N15 compound treatment 513176.0 73800.0 0.44 536766.0 60700.0 0.35 0.5544 0.9929 3071002 PK04_108267 OCC1CC(=NO1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N16 compound treatment 448474.0 9050.0 0.05 419706.0 -56400.0 -0.32 -0.1886 -0.5802 3188788 PK04_108268 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N17 compound treatment 502522.0 63100.0 0.38 565643.0 89600.0 0.51 0.6257 0.9888 3071004 PK04_108269 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N18 compound treatment 457534.0 18100.0 0.11 515814.0 39700.0 0.23 0.236 0.9427 3071005 PK04_108270 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N19 compound treatment 527331.0 87900.0 0.52 558910.0 82800.0 0.47 0.703 0.9986 3414065 PK04_108271 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N20 compound treatment 472414.0 33000.0 0.2 527943.0 51900.0 0.29 0.3474 0.9805 3188790 PK04_108272 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N21 compound treatment 443308.0 3880.0 0.02 527339.0 51300.0 0.29 0.2225 0.7608 3071008 PK04_108273 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N22 compound treatment 523165.0 83700.0 0.5 499111.0 23000.0 0.13 0.445 0.8636 3188791 PK04_108274 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N23 compound treatment 469233.0 29800.0 0.18 545561.0 69500.0 0.4 0.4048 0.9347 3188792 PK04_108275 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 N24 compound treatment 404980.0 -34400.0 -0.2 536772.0 60700.0 0.35 0.0991 0.2469 3188793 PK04_108276 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O01 compound treatment 105081.0 -334000.0 -1.99 271727.0 -204000.0 -1.16 -2.2287 -0.9672 3071055 PK04_108277 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O02 compound treatment 434904.0 -4520.0 -0.03 422347.0 -53700.0 -0.31 -0.2351 -0.7664 2129060 PK04_108278 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O03 compound treatment 68303.0 -371000.0 -2.21 30464.0 -446000.0 -2.53 -3.3537 -0.9977 3188794 PK04_108279 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O04 compound treatment 498217.0 58800.0 0.35 559623.0 83500.0 0.48 0.5834 0.9887 2129057 PK04_108280 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O05 compound treatment 433158.0 -6270.0 -0.04 428767.0 -47300.0 -0.27 -0.2166 -0.7975 3188796 PK04_108281 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O06 compound treatment 62022.0 -377000.0 -2.25 67713.0 -408000.0 -2.32 -3.2303 -0.9999 2129061 PK04_108282 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O07 compound treatment 308038.0 -131000.0 -0.78 291334.0 -185000.0 -1.05 -1.2958 -0.9894 3071060 PK04_108283 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O08 compound treatment 406533.0 -32900.0 -0.2 512180.0 36100.0 0.21 0.0067 0.0238 2129067 PK04_108284 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O09 compound treatment 68515.0 -371000.0 -2.21 60806.0 -415000.0 -2.36 -3.2308 -0.9994 3188797 PK04_108285 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O10 compound treatment 120061.0 -319000.0 -1.9 226964.0 -249000.0 -1.42 -2.3457 -0.9895 2129068 PK04_108286 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O11 mock treatment 492675.0 53300.0 0.32 569155.0 93100.0 0.53 0.5984 0.9699 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O12 mock treatment 486373.0 46900.0 0.28 578073.0 102000.0 0.58 0.6077 0.9439 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O13 compound treatment 401548.0 -37900.0 -0.23 454719.0 -21400.0 -0.12 -0.2453 -0.9579 3188798 PK04_108287 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O14 compound treatment 528762.0 89300.0 0.53 557554.0 81500.0 0.46 0.7036 0.9976 3071064 PK04_108288 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O15 compound treatment 67277.0 -372000.0 -2.21 416140.0 -59900.0 -0.34 -1.8071 -0.8064 3188799 PK04_108289 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O16 compound treatment 536573.0 97100.0 0.58 533265.0 57200.0 0.33 0.6388 0.963 2133032 PK04_108290 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O17 compound treatment 196036.0 -243000.0 -1.45 169230.0 -307000.0 -1.74 -2.2581 -0.9957 3071066 PK04_108291 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O18 compound treatment 596457.0 157000.0 0.93 563025.0 86900.0 0.49 1.0105 0.9557 2133035 PK04_108292 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O19 compound treatment 506616.0 67200.0 0.4 590512.0 114000.0 0.65 0.7429 0.9727 3071068 PK04_108293 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O20 compound treatment 585946.0 147000.0 0.87 539108.0 63000.0 0.36 0.87 0.9228 2133267 PK04_108294 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O21 compound treatment 57779.0 -382000.0 -2.27 63242.0 -413000.0 -2.35 -3.2662 -0.9999 3071112 PK04_108295 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O22 compound treatment 475934.0 36500.0 0.22 516682.0 40600.0 0.23 0.3169 0.9995 2133153 PK04_108296 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O23 compound treatment 59623.0 -380000.0 -2.26 92131.0 -384000.0 -2.18 -3.1422 -0.9999 3188804 PK04_108297 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 O24 compound treatment 462748.0 23300.0 0.14 471765.0 -4320.0 -0.02 0.0808 0.5732 2132929 PK04_108298 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P01 compound treatment 590288.0 151000.0 0.9 550157.0 74100.0 0.42 0.9328 0.9405 3188805 PK04_108299 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P02 compound treatment 440400.0 977.0 0.01 422687.0 -53400.0 -0.3 -0.2106 -0.6934 3071118 PK04_108300 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P03 compound treatment 477894.0 38500.0 0.23 520336.0 44300.0 0.25 0.3399 0.9989 3188806 PK04_108301 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P04 compound treatment 433673.0 -5750.0 -0.03 530739.0 54700.0 0.31 0.1956 0.6255 3071120 PK04_108302 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P05 compound treatment 515256.0 75800.0 0.45 498708.0 22600.0 0.13 0.4101 0.8739 3188807 PK04_108303 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P06 compound treatment 494581.0 55200.0 0.33 542817.0 66700.0 0.38 0.5005 0.9974 3188808 PK04_108304 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P07 compound treatment 217421.0 -222000.0 -1.32 569031.0 92900.0 0.53 -0.5605 -0.3939 3071124 PK04_108305 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P08 compound treatment 505454.0 66000.0 0.39 549134.0 73100.0 0.42 0.5716 0.9996 3188923 PK04_108306 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P09 compound treatment 414158.0 -25300.0 -0.15 529727.0 53600.0 0.31 0.1094 0.3216 3188924 PK04_108307 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P10 compound treatment 341361.0 -98100.0 -0.58 221310.0 -255000.0 -1.45 -1.4371 -0.9201 3071127 PK04_108308 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P11 mock treatment 492374.0 53000.0 0.32 612653.0 137000.0 0.78 0.772 0.9211 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P12 mock treatment 502411.0 63000.0 0.37 523101.0 47000.0 0.27 0.4541 0.9863 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P13 compound treatment 475395.0 36000.0 0.21 396511.0 -79600.0 -0.45 -0.1686 -0.3368 3188925 PK04_108309 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P14 compound treatment 480172.0 40700.0 0.24 569753.0 93700.0 0.53 0.5481 0.9365 3071425 PK04_108310 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P15 compound treatment 445265.0 5840.0 0.03 514652.0 38600.0 0.22 0.1797 0.8091 3188926 PK04_108311 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P16 compound treatment 503751.0 64300.0 0.38 434492.0 -41600.0 -0.24 0.1035 0.2299 3215868 PK04_108312 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P17 compound treatment 532824.0 93400.0 0.56 391858.0 -84200.0 -0.48 0.0544 0.0741 3188927 PK04_108313 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P18 compound treatment 517511.0 78100.0 0.46 483009.0 6930.0 0.04 0.3565 0.7643 3215866 PK04_108314 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P19 compound treatment 514488.0 75100.0 0.45 536931.0 60800.0 0.35 0.5606 0.992 3071435 PK04_108315 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P20 compound treatment 461926.0 22500.0 0.13 525366.0 49300.0 0.28 0.2929 0.9429 3071437 PK04_108316 OB1OC(CCc2ccccc2)CC=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P21 compound treatment 530826.0 91400.0 0.54 547547.0 71500.0 0.41 0.672 0.9897 3188929 PK04_108317 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P22 compound treatment 235555.0 -204000.0 -1.21 281802.0 -194000.0 -1.1 -1.6392 -0.9989 3071483 PK04_108318 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P23 compound treatment 300079.0 -139000.0 -0.83 330075.0 -146000.0 -0.83 -1.1735 -1.0 3188930 PK04_108319 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2108 P24 compound treatment 481049.0 41600.0 0.25 518418.0 42300.0 0.24 0.3454 0.9999 3071486 PK04_108320 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A01 compound treatment 602270.0 37600.0 0.22 480592.0 64500.0 0.37 0.4178 0.972 3131442 CMLD2_000001 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A02 compound treatment 98804.0 -466000.0 -2.77 241575.0 -174000.0 -0.99 -2.662 -0.904 3131443 CMLD2_000002 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A03 compound treatment 660986.0 96400.0 0.57 576935.0 161000.0 0.91 1.0523 0.9747 3010137 CMLD2_000003 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A04 compound treatment 86320.0 -478000.0 -2.85 37920.0 -378000.0 -2.15 -3.5335 -0.9904 3131444 CMLD2_000004 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A05 compound treatment 82353.0 -482000.0 -2.87 62797.0 -353000.0 -2.01 -3.4501 -0.9848 3131445 CMLD2_000005 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A06 compound treatment 600867.0 36200.0 0.22 235354.0 -181000.0 -1.03 -0.5742 -0.5468 3010139 CMLD2_000006 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A07 compound treatment 637203.0 72600.0 0.43 515795.0 99700.0 0.57 0.7064 0.991 3131446 CMLD2_000007 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A08 compound treatment 642876.0 78200.0 0.47 254541.0 -162000.0 -0.92 -0.3203 -0.311 3010141 CMLD2_000008 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A09 compound treatment 643520.0 78900.0 0.47 295941.0 -120000.0 -0.68 -0.1511 -0.1823 3010141 CMLD2_000009 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A10 compound treatment 617019.0 52400.0 0.31 323195.0 -92900.0 -0.53 -0.153 -0.2495 3010142 CMLD2_000010 CC(C)[C@H](O)C1=CCCCC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A11 compound treatment 653575.0 88900.0 0.53 143823.0 -272000.0 -1.55 -0.7204 -0.4403 3131447 CMLD2_000011 O=C(OCc1ccccc1)C(C2CCCC(=O)C2)C(=O)OCc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A12 compound treatment 152617.0 -412000.0 -2.45 210235.0 -206000.0 -1.17 -2.5616 -0.9427 3010143 CMLD2_000012 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A13 mock treatment 86342.0 -478000.0 -2.85 578768.0 163000.0 0.93 -1.3586 -0.4539 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A14 mock treatment 666812.0 102000.0 0.61 247710.0 -168000.0 -0.96 -0.247 -0.2178 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A15 compound treatment 589072.0 24400.0 0.15 272044.0 -144000.0 -0.82 -0.4763 -0.5726 3131448 CMLD2_000013 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A16 compound treatment 112365.0 -452000.0 -2.69 170178.0 -246000.0 -1.4 -2.892 -0.9535 3131449 CMLD2_000014 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A17 compound treatment 109392.0 -455000.0 -2.71 204415.0 -212000.0 -1.2 -2.7669 -0.9333 3010159 CMLD2_000015 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A18 mock treatment 597582.0 32900.0 0.2 230483.0 -186000.0 -1.06 -0.6076 -0.566 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A19 compound treatment 46964.0 -518000.0 -3.08 257762.0 -158000.0 -0.9 -2.8151 -0.8771 3131450 CMLD2_000016 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A20 compound treatment 534063.0 -30600.0 -0.18 278521.0 -138000.0 -0.78 -0.6817 -0.8489 3010162 CMLD2_000017 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A21 compound treatment 135350.0 -429000.0 -2.55 197228.0 -219000.0 -1.24 -2.6865 -0.9454 3131451 CMLD2_000018 COc1ccc(OC[C@H]2Cc3c(nc4CCN(CCOc5ccccc5)Cc4c3CO2)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A22 compound treatment 152612.0 -412000.0 -2.45 485908.0 69800.0 0.4 -1.4531 -0.585 3131452 CMLD2_000019 COC(=O)C1=C(C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A23 compound treatment 627509.0 62900.0 0.37 485397.0 69300.0 0.39 0.5434 0.9997 3010166 CMLD2_000020 COc1cccc(c1)[C@H]2N[C@@H](CC[C@@H]2C)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 A24 compound treatment 556425.0 -8210.0 -0.05 485457.0 69400.0 0.39 0.2445 0.6149 3010168 CMLD2_000021 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)C)c3ccccc3)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B01 compound treatment 625259.0 60600.0 0.36 599326.0 183000.0 1.04 0.992 0.8995 3131453 CMLD2_000022 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B02 compound treatment 639090.0 74500.0 0.44 326435.0 -89600.0 -0.51 -0.0471 -0.0697 3131569 CMLD2_000023 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B03 compound treatment 81834.0 -483000.0 -2.87 72675.0 -343000.0 -1.95 -3.4126 -0.9823 3131570 CMLD2_000024 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B04 compound treatment 503133.0 -61500.0 -0.37 234321.0 -182000.0 -1.03 -0.9896 -0.9026 3010172 CMLD2_000025 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B05 compound treatment 79580.0 -485000.0 -2.89 62752.0 -353000.0 -2.01 -3.462 -0.9843 3131571 CMLD2_000026 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B06 compound treatment 544962.0 -19700.0 -0.12 212576.0 -203000.0 -1.16 -0.9011 -0.7747 3010200 CMLD2_000027 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B07 compound treatment 682361.0 118000.0 0.7 312197.0 -104000.0 -0.59 0.0777 0.0848 3131572 CMLD2_000028 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B08 compound treatment 579259.0 14600.0 0.09 628591.0 213000.0 1.21 0.9161 0.7561 3010203 CMLD2_000029 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B09 compound treatment 585421.0 20800.0 0.12 539774.0 124000.0 0.7 0.5849 0.8189 3010205 CMLD2_000030 COC(=O)NC/C=C\c1nc(CC/C=C\C(=O)OC)co1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B10 compound treatment 545263.0 -19400.0 -0.12 598077.0 182000.0 1.04 0.6504 0.6245 3131573 CMLD2_000031 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@H](O)c2c(=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B11 compound treatment 391004.0 -174000.0 -1.03 497713.0 81600.0 0.46 -0.4024 -0.3552 3010207 CMLD2_000032 CC1(C)OCC(CO1)C(O)C2=CCCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B12 compound treatment 523192.0 -41400.0 -0.25 549711.0 134000.0 0.76 0.363 0.4543 3131574 CMLD2_000033 COC(=O)[C@H](C)NC(=O)[C@@H](C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B13 mock treatment 632172.0 67500.0 0.4 555968.0 140000.0 0.8 0.8468 0.95 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B14 mock treatment 569522.0 4890.0 0.03 170824.0 -245000.0 -1.39 -0.9656 -0.6922 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B15 compound treatment 593730.0 29100.0 0.17 582781.0 167000.0 0.95 0.7928 0.8227 3010209 CMLD2_000034 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B16 compound treatment 560780.0 -3850.0 -0.02 250940.0 -165000.0 -0.94 -0.6802 -0.7242 2082484 CMLD2_000035 COC(=O)C(C1CCCC(=O)C1)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B17 compound treatment 548546.0 -16100.0 -0.1 154009.0 -262000.0 -1.49 -1.1215 -0.751 3131575 CMLD2_000036 COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B18 mock treatment 609943.0 45300.0 0.27 499678.0 83600.0 0.48 0.5269 0.9639 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B19 compound treatment 499991.0 -64600.0 -0.38 488186.0 72100.0 0.41 0.018 0.0319 3010212 CMLD2_000037 CO[C@@H]1[C@H](O)CO[C@H]1/C=C/c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B20 compound treatment 623624.0 59000.0 0.35 496462.0 80400.0 0.46 0.5715 0.9915 3131576 CMLD2_000038 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B21 compound treatment 570756.0 6120.0 0.04 568669.0 153000.0 0.87 0.6394 0.7362 3010215 CMLD2_000039 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B22 compound treatment 619789.0 55200.0 0.33 517194.0 101000.0 0.58 0.6388 0.9646 3131577 CMLD2_000040 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B23 compound treatment 713729.0 149000.0 0.89 530420.0 114000.0 0.65 1.0873 0.9883 3010186 CMLD2_000041 COc1ccc(cc1)c2ccccc2[C@@H]3N[C@@H](CC[C@H]3C)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 B24 compound treatment 218256.0 -346000.0 -2.06 562822.0 147000.0 0.83 -0.8675 -0.3901 3131578 CMLD2_000042 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCOC4=O)C(=O)CC)c5ccccc5)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C01 compound treatment 102487.0 -462000.0 -2.75 99078.0 -317000.0 -1.8 -3.2195 -0.979 3131579 CMLD2_000043 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7ccccc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C02 compound treatment 647681.0 83000.0 0.49 483608.0 67500.0 0.38 0.6211 0.9922 3010248 CMLD2_000044 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C03 compound treatment 293109.0 -272000.0 -1.62 187062.0 -229000.0 -1.3 -2.0635 -0.9943 3131580 CMLD2_000045 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C04 compound treatment 601077.0 36400.0 0.22 492950.0 76900.0 0.44 0.4625 0.9477 3131581 CMLD2_000046 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3ccc4OCOc4c3)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C05 compound treatment 650160.0 85500.0 0.51 245657.0 -170000.0 -0.97 -0.3253 -0.2972 3131582 CMLD2_000047 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C06 compound treatment 547045.0 -17600.0 -0.1 403866.0 -12200.0 -0.07 -0.1231 -0.9801 3010252 CMLD2_000048 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C07 compound treatment 192375.0 -372000.0 -2.22 295414.0 -121000.0 -0.69 -2.0517 -0.8846 3131583 CMLD2_000049 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C08 compound treatment 494219.0 -70400.0 -0.42 484125.0 68100.0 0.39 -0.0227 -0.0397 3010254 CMLD2_000050 Cc1cc2N(CC(O)CN3CCCc4nc(C)c(C)cc34)CCCc2nc1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C09 compound treatment 55180.0 -509000.0 -3.03 102464.0 -314000.0 -1.78 -3.405 -0.968 3131584 CMLD2_000051 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C10 compound treatment 76562.0 -488000.0 -2.9 69567.0 -347000.0 -1.97 -3.4473 -0.9821 3010257 CMLD2_000052 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@@H](O)c2c(=O)o1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C11 mock treatment 564970.0 337.0 0.0 511420.0 95400.0 0.54 0.3848 0.7097 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C12 mock treatment 559514.0 -5120.0 -0.03 219513.0 -197000.0 -1.12 -0.8119 -0.7261 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C13 compound treatment 127838.0 -437000.0 -2.6 519554.0 103000.0 0.59 -1.422 -0.5335 3010259 CMLD2_000053 OC(CCOCc1ccccc1)C2=CCCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C14 compound treatment 586280.0 21600.0 0.13 293505.0 -123000.0 -0.7 -0.4018 -0.5668 1304363 CMLD2_000054 C1Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C15 mock treatment 546182.0 -18500.0 -0.11 258882.0 -157000.0 -0.89 -0.7097 -0.788 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C16 mock treatment 581633.0 17000.0 0.1 240282.0 -176000.0 -1.0 -0.6353 -0.6323 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C17 compound treatment 358511.0 -206000.0 -1.23 178812.0 -237000.0 -1.35 -1.8215 -0.9989 3010233 CMLD2_000055 COc1ccc(cc1)c2cnnc(CCCn3ccnc3c4ccccc4)n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C18 compound treatment 301062.0 -264000.0 -1.57 341084.0 -75000.0 -0.43 -1.4107 -0.8678 3131585 CMLD2_000056 Cc1ccc(O[C@H]2C=C[C@@H](CC=C)O[C@@H]2COC(=O)NCc3cccc4ccccc34)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C19 compound treatment 63241.0 -501000.0 -2.98 54766.0 -361000.0 -2.05 -3.5629 -0.9834 3131586 CMLD2_000057 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2ccc(cc2)C(=O)OC)C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C20 compound treatment 119124.0 -446000.0 -2.65 330813.0 -85300.0 -0.48 -2.2177 -0.8228 3010236 CMLD2_000058 C[C@H]1CC[C@@H]2N(CC(CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C21 compound treatment 198657.0 -366000.0 -2.18 182261.0 -234000.0 -1.33 -2.4803 -0.972 3131587 CMLD2_000059 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2CC1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C22 compound treatment 567143.0 2510.0 0.01 450400.0 34300.0 0.2 0.1486 0.759 3131703 CMLD2_000060 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C23 compound treatment 613852.0 49200.0 0.29 469990.0 53900.0 0.31 0.424 0.9997 3010240 CMLD2_000061 OC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 C24 compound treatment 691313.0 127000.0 0.75 500103.0 84000.0 0.48 0.871 0.9758 3131704 CMLD2_000062 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C4=O)c5ccccc5)C(=O)OC)c6ccccc6)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D01 compound treatment 568001.0 3370.0 0.02 474127.0 58100.0 0.33 0.2476 0.7487 3010292 CMLD2_000063 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D02 compound treatment 87530.0 -477000.0 -2.84 76558.0 -340000.0 -1.93 -3.373 -0.9823 3131705 CMLD2_000064 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D03 compound treatment 450812.0 -114000.0 -0.68 388374.0 -27700.0 -0.16 -0.5904 -0.8489 3131706 CMLD2_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D04 compound treatment 96002.0 -469000.0 -2.79 115152.0 -301000.0 -1.71 -3.1822 -0.9725 3010296 CMLD2_000066 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D05 compound treatment 592071.0 27400.0 0.16 568806.0 153000.0 0.87 0.7296 0.8256 3010274 CMLD2_000067 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D06 compound treatment 561177.0 -3460.0 -0.02 439066.0 23000.0 0.13 0.0779 0.5887 3131707 CMLD2_000068 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D07 compound treatment 515815.0 -48800.0 -0.29 446712.0 30600.0 0.17 -0.0822 -0.2427 3131708 CMLD2_000069 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D08 compound treatment 157099.0 -408000.0 -2.43 187974.0 -228000.0 -1.3 -2.6322 -0.957 3010278 CMLD2_000070 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D09 compound treatment 540429.0 -24200.0 -0.14 501452.0 85400.0 0.49 0.2415 0.4768 3010279 CMLD2_000071 CN1CCN(CC(O)CN2CCCc3nc(C)c(C)cc23)CC1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D10 compound treatment 546547.0 -18100.0 -0.11 416308.0 238.0 0.0 -0.0752 -0.6981 3131709 CMLD2_000072 C[C@@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D11 mock treatment 446770.0 -118000.0 -0.7 456815.0 40700.0 0.23 -0.3322 -0.4496 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D12 mock treatment 478306.0 -86300.0 -0.51 263459.0 -153000.0 -0.87 -0.977 -0.9687 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D13 compound treatment 75934.0 -489000.0 -2.91 75840.0 -340000.0 -1.93 -3.4247 -0.9804 3010281 CMLD2_000073 Brc1ccc(cc1)C(=O)OC(CCc2ccccc2)C3=CCCCC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D14 compound treatment 555265.0 -9370.0 -0.06 468419.0 52300.0 0.3 0.1711 0.5649 3131710 CMLD2_000074 CCOC(=O)CC(C1CCCCC1=O)C(=O)OCC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D15 mock treatment 568693.0 4060.0 0.02 487179.0 71100.0 0.4 0.303 0.748 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D16 mock treatment 512095.0 -52500.0 -0.31 454134.0 38100.0 0.22 -0.068 -0.1789 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D17 compound treatment 544013.0 -20600.0 -0.12 478762.0 62700.0 0.36 0.1653 0.4385 3131711 CMLD2_000075 COC(=O)C/C=C/[C@H](C)[C@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D18 compound treatment 78952.0 -486000.0 -2.89 86524.0 -330000.0 -1.87 -3.369 -0.978 3010283 CMLD2_000076 CCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D19 compound treatment 64203.0 -500000.0 -2.98 52507.0 -364000.0 -2.07 -3.5679 -0.9841 3131712 CMLD2_000077 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D20 compound treatment 554063.0 -10600.0 -0.06 240763.0 -175000.0 -1.0 -0.7494 -0.7502 3010285 CMLD2_000078 COC(=O)[C@@H]1CC[C@@H](C)[C@@H](N1)c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D21 compound treatment 152397.0 -412000.0 -2.45 503000.0 86900.0 0.49 -1.3852 -0.5535 3131713 CMLD2_000079 C[C@@H]1Cc2c(CO1)cnc3CCN(C)Cc32 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D22 compound treatment 108485.0 -456000.0 -2.71 84373.0 -332000.0 -1.89 -3.2534 -0.9842 3131714 CMLD2_000080 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D23 compound treatment 536716.0 -27900.0 -0.17 434500.0 18400.0 0.1 -0.0434 -0.2208 3010288 CMLD2_000081 COc1cc(cc(OC)c1OC)[C@@H]2N[C@@H](Cc3c2[nH]c4ccccc34)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 D24 compound treatment 622761.0 58100.0 0.35 489443.0 73400.0 0.42 0.5397 0.9957 3131715 CMLD2_000082 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E01 mock treatment 596470.0 31800.0 0.19 509526.0 93500.0 0.53 0.5098 0.9035 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E02 mock treatment 551446.0 -13200.0 -0.08 461602.0 45500.0 0.26 0.1276 0.4716 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E03 compound treatment 78132.0 -487000.0 -2.9 66971.0 -349000.0 -1.99 -3.4511 -0.9831 3010304 CMLD2_000083 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E04 compound treatment 96524.0 -468000.0 -2.79 104722.0 -311000.0 -1.77 -3.2219 -0.9761 3131716 CMLD2_000084 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E05 compound treatment 650826.0 86200.0 0.51 498794.0 82700.0 0.47 0.6954 0.9991 3131717 CMLD2_000085 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E06 compound treatment 82470.0 -482000.0 -2.87 80501.0 -336000.0 -1.91 -3.3784 -0.9804 3010306 CMLD2_000086 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E07 compound treatment 96525.0 -468000.0 -2.79 67213.0 -349000.0 -1.98 -3.3727 -0.9862 3131718 CMLD2_000087 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E08 compound treatment 219364.0 -345000.0 -2.05 151879.0 -264000.0 -1.5 -2.5153 -0.9882 3131719 CMLD2_000088 Brc1ccc(cc1)c2ccc3N(CCCc3n2)C(=O)NCCCN4=CC=NC4c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E09 mock treatment 548506.0 -16100.0 -0.1 194860.0 -221000.0 -1.26 -0.9574 -0.7588 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E10 mock treatment 57232.0 -507000.0 -3.02 361088.0 -55000.0 -0.31 -2.3564 -0.7762 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E11 compound treatment 509494.0 -55100.0 -0.33 168566.0 -248000.0 -1.41 -1.2273 -0.8492 3010320 CMLD2_000089 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)NCc3cccc4ccccc34)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E12 compound treatment 552797.0 -11800.0 -0.07 203814.0 -212000.0 -1.21 -0.9033 -0.7471 3131720 CMLD2_000090 CC(C)C(=O)N[C@H]1CCCN1C(=O)/C=C/c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E13 compound treatment 490359.0 -74300.0 -0.44 427826.0 11800.0 0.07 -0.2653 -0.5934 3010323 CMLD2_000091 OC(COCc1ccccc1)C2=CCCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E14 compound treatment 213193.0 -351000.0 -2.09 85399.0 -331000.0 -1.88 -2.8086 -0.9986 3131721 CMLD2_000092 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3ccccc3O[C@]2([C@@H]1c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E15 compound treatment 299110.0 -266000.0 -1.58 290863.0 -125000.0 -0.71 -1.6209 -0.9352 3010326 CMLD2_000093 COc1cc(O)c(C(=O)/C=C/c2ccc3OCOc3c2)c(OC)c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E16 mock treatment 506623.0 -58000.0 -0.35 493714.0 77600.0 0.44 0.0681 0.1215 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E17 mock treatment 527457.0 -37200.0 -0.22 166431.0 -250000.0 -1.42 -1.1603 -0.8076 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E18 mock treatment 576647.0 12000.0 0.07 450820.0 34800.0 0.2 0.1903 0.9055 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E19 compound treatment 214991.0 -350000.0 -2.08 150700.0 -265000.0 -1.51 -2.5385 -0.9876 3131722 CMLD2_000094 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E20 compound treatment 210846.0 -354000.0 -2.11 477907.0 61800.0 0.35 -1.2402 -0.581 3131840 CMLD2_000095 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)C(F)(F)F)c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E21 compound treatment 550595.0 -14000.0 -0.08 479348.0 63300.0 0.36 0.1954 0.5289 3010332 CMLD2_000096 C1Cc2nc(c3ccccc3)c(cc2CN1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E22 compound treatment 550508.0 -14100.0 -0.08 442014.0 25900.0 0.15 0.0449 0.2643 3131841 CMLD2_000097 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCOC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E23 compound treatment 420698.0 -144000.0 -0.86 431724.0 15700.0 0.09 -0.5428 -0.6302 3010340 CMLD2_000098 C[C@H]1CC[C@H](N[C@@H]1c2cccc(CC=C)c2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 E24 compound treatment 675399.0 111000.0 0.66 512312.0 96200.0 0.55 0.8531 0.9957 3131842 CMLD2_000099 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCCC4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F01 mock treatment 566376.0 1740.0 0.01 626168.0 210000.0 1.19 0.8522 0.7132 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F02 mock treatment 566392.0 1760.0 0.01 269656.0 -146000.0 -0.83 -0.5813 -0.6982 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F03 compound treatment 315385.0 -249000.0 -1.48 131953.0 -284000.0 -1.62 -2.1914 -0.9991 3131843 CMLD2_000100 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F04 compound treatment 521892.0 -42700.0 -0.25 367457.0 -48600.0 -0.28 -0.3753 -0.9991 3010347 CMLD2_000101 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F05 compound treatment 633703.0 69100.0 0.41 535967.0 120000.0 0.68 0.7728 0.9707 3131844 CMLD2_000102 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F06 compound treatment 468181.0 -96500.0 -0.57 449510.0 33400.0 0.19 -0.2714 -0.4489 3131845 CMLD2_000103 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F07 compound treatment 68718.0 -496000.0 -2.95 70486.0 -346000.0 -1.97 -3.4766 -0.9805 3011245 CMLD2_000104 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F08 compound treatment 408333.0 -156000.0 -0.93 270264.0 -146000.0 -0.83 -1.2441 -0.9984 3010203 CMLD2_000105 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F09 mock treatment 587286.0 22700.0 0.13 243958.0 -172000.0 -0.98 -0.5968 -0.604 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F10 mock treatment 585854.0 21200.0 0.13 262033.0 -154000.0 -0.88 -0.5301 -0.599 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F11 compound treatment 251482.0 -313000.0 -1.86 99865.0 -316000.0 -1.8 -2.5893 -0.9998 3011246 CMLD2_000106 C[C@@]12CCC3C(CCc4cc(OCC5CO5)ccc34)C2CC[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F12 compound treatment 451045.0 -114000.0 -0.68 442310.0 26200.0 0.15 -0.3725 -0.5381 3011247 CMLD2_000107 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F13 compound treatment 260841.0 -304000.0 -1.81 64059.0 -352000.0 -2.0 -2.6939 -0.9987 3131846 CMLD2_000108 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(Br)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F14 compound treatment 537935.0 -26700.0 -0.16 451811.0 35700.0 0.2 0.0314 0.1216 3011248 CMLD2_000109 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F15 compound treatment 113837.0 -451000.0 -2.68 78226.0 -338000.0 -1.92 -3.2556 -0.9866 1946418 CMLD2_000110 Fc1ccc(cc1)C(=O)/C=C/c2ccc3OCOc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F16 compound treatment 75308.0 -489000.0 -2.91 74728.0 -341000.0 -1.94 -3.4318 -0.9806 3011250 CMLD2_000111 OC(CCOC(c1ccccc1)(c2ccccc2)c3ccccc3)C4=CCCCC4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F17 mock treatment 552839.0 -11800.0 -0.07 444651.0 28600.0 0.16 0.0653 0.3688 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F18 mock treatment 515900.0 -48700.0 -0.29 212692.0 -203000.0 -1.16 -1.0229 -0.8579 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F19 compound treatment 560059.0 -4570.0 -0.03 482600.0 66500.0 0.38 0.2483 0.6545 3131847 CMLD2_000112 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F20 compound treatment 534093.0 -30500.0 -0.18 479155.0 63100.0 0.36 0.1252 0.3112 3131848 CMLD2_000113 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1)c2ccc(Br)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F21 compound treatment 546795.0 -17800.0 -0.11 180871.0 -235000.0 -1.34 -1.0208 -0.7608 3011251 CMLD2_000114 CN1CCc2nc(CO)c(CO)cc2C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F22 compound treatment 530774.0 -33900.0 -0.2 497580.0 81500.0 0.46 0.1853 0.3666 3131849 CMLD2_000115 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F23 compound treatment 647371.0 82700.0 0.49 445613.0 29500.0 0.17 0.467 0.8976 3011252 CMLD2_000116 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(c3)N4CCOCC4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6cccc(c6)N7CCOCC7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 F24 compound treatment 373385.0 -191000.0 -1.14 239773.0 -176000.0 -1.0 -1.5137 -0.998 3131850 CMLD2_000117 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C)C4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G01 compound treatment 568127.0 3490.0 0.02 439450.0 23400.0 0.13 0.1087 0.8079 3131851 CMLD2_000118 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCN3CCOCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G02 compound treatment 86296.0 -478000.0 -2.85 69613.0 -346000.0 -1.97 -3.4061 -0.9838 3131852 CMLD2_000119 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G03 mock treatment 511541.0 -53100.0 -0.32 238349.0 -178000.0 -1.01 -0.9381 -0.8859 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G04 mock treatment 553845.0 -10800.0 -0.06 516571.0 101000.0 0.57 0.3587 0.6238 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G05 compound treatment 593282.0 28600.0 0.17 330832.0 -85200.0 -0.48 -0.2222 -0.4324 3011253 CMLD2_000120 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G06 compound treatment 301307.0 -263000.0 -1.57 362720.0 -53300.0 -0.3 -1.3227 -0.8286 3131853 CMLD2_000121 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G07 compound treatment 75790.0 -489000.0 -2.91 72562.0 -344000.0 -1.95 -3.4385 -0.9812 3011254 CMLD2_000122 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)OC2CC(CCC3CC(=NO3)CC)OC4(CCCC(COC(=O)NCCC(C)C)O4)C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G08 compound treatment 628461.0 63800.0 0.38 365226.0 -50800.0 -0.29 0.0642 0.1344 3131854 CMLD2_000123 Cc1ccc(cc1)S(=O)(=O)NC(CCc2ccccc2)CC(=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G09 compound treatment 528603.0 -36000.0 -0.21 210211.0 -206000.0 -1.17 -0.9794 -0.8229 3131855 CMLD2_000124 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)N3CCCCC3)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G10 compound treatment 596401.0 31800.0 0.19 207611.0 -208000.0 -1.19 -0.7046 -0.5869 3011255 CMLD2_000125 O[C@H]1C=C(C=C)C2(OCCCO2)[C@H]3O[C@H]31 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G11 compound treatment 548962.0 -15700.0 -0.09 289525.0 -127000.0 -0.72 -0.5748 -0.7921 3011256 CMLD2_000126 OC(CCc1ccccc1)C2=CCCOC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G12 compound treatment 123951.0 -441000.0 -2.62 130096.0 -286000.0 -1.63 -3.0045 -0.9736 3131856 CMLD2_000127 C[C@H]1OC=C2[C@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](OC(=O)C)[C@H]7O[C@H]7C6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G13 compound treatment 587285.0 22700.0 0.13 444911.0 28800.0 0.16 0.2113 0.9953 3011257 CMLD2_000128 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G14 compound treatment 25693.0 -539000.0 -3.21 65655.0 -350000.0 -1.99 -3.6771 -0.9738 3131857 CMLD2_000129 CC/C=C\CCC(OC(=O)c1ccc(Br)cc1)C2=CCCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G15 compound treatment 564752.0 119.0 0.0 450733.0 34700.0 0.2 0.1399 0.7097 3011258 CMLD2_000130 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G16 mock treatment 516812.0 -47800.0 -0.28 409051.0 -7020.0 -0.04 -0.2295 -0.7985 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G17 compound treatment 398837.0 -166000.0 -0.99 529167.0 113000.0 0.64 -0.2429 -0.2063 3131858 CMLD2_000131 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G18 compound treatment 63621.0 -501000.0 -2.98 66802.0 -349000.0 -1.99 -3.5129 -0.9805 3131859 CMLD2_000132 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G19 mock treatment 140268.0 -424000.0 -2.53 430017.0 13900.0 0.08 -1.7298 -0.6846 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G20 mock treatment 517824.0 -46800.0 -0.28 285506.0 -131000.0 -0.74 -0.722 -0.9104 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G21 compound treatment 591702.0 27100.0 0.16 469729.0 53700.0 0.31 0.3297 0.9554 3011259 CMLD2_000133 CN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G22 compound treatment 653721.0 89100.0 0.53 224095.0 -192000.0 -1.09 -0.397 -0.3272 3131977 CMLD2_000134 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G23 compound treatment 52802.0 -512000.0 -3.05 62128.0 -354000.0 -2.01 -3.5772 -0.9798 3011260 CMLD2_000135 C[C@H]1CC[C@@H]2N([C@@H]1c3cccc(CC=C)c3)C(=O)[C@@H]4CC[C@H](C)[C@H](N4C2=O)c5cccc(CC=C)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 G24 compound treatment 684288.0 120000.0 0.71 567843.0 152000.0 0.86 1.1138 0.9954 3131978 CMLD2_000136 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H01 compound treatment 648632.0 84000.0 0.5 424994.0 8920.0 0.05 0.3894 0.7749 3131979 CMLD2_000137 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H02 compound treatment 600068.0 35400.0 0.21 296207.0 -120000.0 -0.68 -0.3329 -0.4665 3131980 CMLD2_000138 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H03 mock treatment 534672.0 -30000.0 -0.18 323090.0 -93000.0 -0.53 -0.5 -0.896 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H04 mock treatment 602413.0 37800.0 0.22 375824.0 -40200.0 -0.23 -0.0028 -0.0089 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H05 compound treatment 573843.0 9210.0 0.05 275132.0 -141000.0 -0.8 -0.528 -0.6572 3011261 CMLD2_000139 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H06 compound treatment 56821.0 -508000.0 -3.02 69524.0 -347000.0 -1.97 -3.5305 -0.9785 3131981 CMLD2_000140 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H07 compound treatment 52737.0 -512000.0 -3.05 55597.0 -360000.0 -2.05 -3.6037 -0.9814 3422360 CMLD2_000141 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H08 compound treatment 464448.0 -100000.0 -0.6 330206.0 -85900.0 -0.49 -0.7669 -0.9951 3010278 CMLD2_000142 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H09 compound treatment 519454.0 -45200.0 -0.27 378261.0 -37800.0 -0.22 -0.3422 -0.9939 3011262 CMLD2_000143 CON(C)C(=O)c1nnc2c3ccccc3[nH]c2n1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H10 compound treatment 57541.0 -507000.0 -3.02 77601.0 -338000.0 -1.92 -3.495 -0.9764 3011263 CMLD2_000144 C/C=C/C1=C(CO)C(=O)[C@@H]2O[C@@H]2C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H11 compound treatment 439602.0 -125000.0 -0.74 459406.0 43300.0 0.25 -0.3519 -0.4489 3011264 CMLD2_000145 CCOC(=O)CC(CC(=O)C)C(=O)OCC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H12 compound treatment 392424.0 -172000.0 -1.02 351206.0 -64900.0 -0.37 -0.9855 -0.9048 3131982 CMLD2_000146 CCOC(=O)C1=NO[C@@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H13 compound treatment 612658.0 48000.0 0.29 556328.0 140000.0 0.8 0.7661 0.9042 3011265 CMLD2_000147 OC(C1CCCCC1)C2=CCCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H14 compound treatment 627049.0 62400.0 0.37 194197.0 -222000.0 -1.26 -0.6295 -0.4786 3011266 CMLD2_000148 OC(C1=CCCCC1=O)c2ccc(cc2)[N+](=O)[O-] 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H15 compound treatment 565727.0 1090.0 0.01 175485.0 -241000.0 -1.37 -0.9628 -0.7037 3131983 CMLD2_000149 CC1(C)O[C@H]2OC([C@H](O)CON3C(=O)c4ccccc4C3=O)[C@H](O)[C@H]2O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H16 compound treatment 222983.0 -342000.0 -2.03 61665.0 -354000.0 -2.02 -2.8629 -1.0 3011267 CMLD2_000150 COCOc1ccc(Br)cc1C(=O)[C@@H]2O[C@H]2c3cccc(OC)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H17 compound treatment 505987.0 -58600.0 -0.35 403590.0 -12500.0 -0.07 -0.297 -0.8338 3131984 CMLD2_000151 C[C@@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@]42[C@H]5O[C@H](C)[C@@H]([C@@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H18 compound treatment 72364.0 -492000.0 -2.93 50603.0 -365000.0 -2.08 -3.5412 -0.9859 3011268 CMLD2_000152 COc1ccc(C#C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H19 mock treatment 537541.0 -27100.0 -0.16 186875.0 -229000.0 -1.3 -1.0356 -0.7886 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H20 mock treatment 585490.0 20900.0 0.12 437529.0 21500.0 0.12 0.1741 1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H21 compound treatment 494898.0 -69700.0 -0.42 338145.0 -77900.0 -0.44 -0.6068 -0.9995 3131985 CMLD2_000153 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H22 compound treatment 617446.0 52800.0 0.31 458104.0 42000.0 0.24 0.3913 0.9909 3131715 CMLD2_000154 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H23 compound treatment 237314.0 -327000.0 -1.95 222796.0 -193000.0 -1.1 -2.1546 -0.9633 3011247 CMLD2_000155 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 H24 compound treatment 579863.0 15200.0 0.09 459879.0 43800.0 0.25 0.2403 0.9063 3131986 CMLD2_000156 COC(=O)C1=C(C)N(Cc2ccccc2)c3c(C(=O)OC)c(C(=O)OC)c(C(=O)OC)c(=O)n3[C@@H]1c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I01 compound treatment 505549.0 -59100.0 -0.35 465545.0 49500.0 0.28 -0.0497 -0.1103 3131987 CMLD2_000157 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I02 compound treatment 446388.0 -118000.0 -0.7 486240.0 70200.0 0.4 -0.2154 -0.2663 3011269 CMLD2_000158 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3cccc4ccccc34)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I03 compound treatment 77172.0 -487000.0 -2.9 78578.0 -337000.0 -1.92 -3.4085 -0.9799 3131988 CMLD2_000159 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I04 compound treatment 558779.0 -5850.0 -0.03 521400.0 105000.0 0.6 0.3989 0.6649 3011270 CMLD2_000160 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I05 mock treatment 126301.0 -438000.0 -2.61 539362.0 123000.0 0.7 -1.3488 -0.4993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I06 mock treatment 190242.0 -374000.0 -2.23 500668.0 84600.0 0.48 -1.2354 -0.5419 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I07 compound treatment 592846.0 28200.0 0.17 484890.0 68800.0 0.39 0.3955 0.9286 3422373 CMLD2_000161 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I08 compound treatment 560192.0 -4440.0 -0.03 476635.0 60600.0 0.34 0.2249 0.6509 3011271 CMLD2_000162 COC(=O)NC/C=C\c1nc(CCCO)co1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I09 compound treatment 279508.0 -285000.0 -1.7 440724.0 24700.0 0.14 -1.1007 -0.6465 3131989 CMLD2_000163 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I10 compound treatment 592451.0 27800.0 0.17 272997.0 -143000.0 -0.81 -0.4582 -0.5519 3011272 CMLD2_000164 CO[C@@H]1[C@@H](C)/C(=C\CC(=O)OC)/c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I11 compound treatment 571272.0 6640.0 0.04 479517.0 63400.0 0.36 0.2831 0.7799 3131990 CMLD2_000165 CC(=NOCc1ccc(cc1)c2cc(no2)c3ccccc3)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I12 compound treatment 546567.0 -18100.0 -0.11 485406.0 69300.0 0.39 0.2028 0.4962 3131991 CMLD2_000166 COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I13 compound treatment 122835.0 -442000.0 -2.63 472915.0 56800.0 0.32 -1.6306 -0.6155 3011273 CMLD2_000167 C=CC(=O)N1C(=O)c2ccccc2S1(=O)=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I14 compound treatment 49328.0 -515000.0 -3.07 67489.0 -349000.0 -1.98 -3.5702 -0.9777 3131992 CMLD2_000168 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#Cc3ccccc3)cc2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I15 compound treatment 132161.0 -432000.0 -2.57 454290.0 38200.0 0.22 -1.6663 -0.6451 3011274 CMLD2_000169 CC(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I16 mock treatment 499150.0 -65500.0 -0.39 465983.0 49900.0 0.28 -0.0749 -0.1553 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I17 compound treatment 47524.0 -517000.0 -3.08 66668.0 -349000.0 -1.99 -3.5811 -0.9776 3131993 CMLD2_000170 C[C@H]1OC=C2[C@H](O)C3O[C@@H]3/C(=N\OCc4ccccc4)/[C@@]52[C@H]6OC(C)[C@@H](C15)C7=C6[C@H](O)[C@H]8O[C@H]8C7=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I18 compound treatment 68735.0 -496000.0 -2.95 67407.0 -349000.0 -1.98 -3.4889 -0.9813 3011312 CMLD2_000171 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I19 compound treatment 581698.0 17100.0 0.1 526546.0 110000.0 0.63 0.5161 0.8109 3131989 CMLD2_000172 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I20 compound treatment 571925.0 7290.0 0.04 279206.0 -137000.0 -0.78 -0.5197 -0.6666 3011257 CMLD2_000173 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I21 mock treatment 607272.0 42600.0 0.25 478018.0 61900.0 0.35 0.4285 0.987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I22 mock treatment 565918.0 1290.0 0.01 451224.0 35200.0 0.2 0.1468 0.7336 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I23 compound treatment 671524.0 107000.0 0.64 126334.0 -290000.0 -1.65 -0.7152 -0.405 3132111 CMLD2_000174 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(NC(=O)C)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(NC(=O)C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 I24 compound treatment 591603.0 27000.0 0.16 405181.0 -10900.0 -0.06 0.0697 0.4052 3131703 CMLD2_000175 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J01 compound treatment 469705.0 -94900.0 -0.56 511508.0 95400.0 0.54 -0.0157 -0.0201 3132112 CMLD2_000176 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J02 compound treatment 78535.0 -486000.0 -2.89 84092.0 -332000.0 -1.89 -3.3806 -0.9786 3011347 CMLD2_000177 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J03 compound treatment 227221.0 -337000.0 -2.01 523995.0 108000.0 0.61 -0.9859 -0.4695 3132113 CMLD2_000178 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J04 compound treatment 550952.0 -13700.0 -0.08 289855.0 -126000.0 -0.72 -0.5651 -0.7823 3132114 CMLD2_000179 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J05 mock treatment 536967.0 -27700.0 -0.16 251450.0 -165000.0 -0.94 -0.7784 -0.8189 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J06 mock treatment 501574.0 -63100.0 -0.38 445580.0 29500.0 0.17 -0.1467 -0.3569 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J07 compound treatment 49653.0 -515000.0 -3.06 77168.0 -339000.0 -1.93 -3.53 -0.975 3011348 CMLD2_000180 CC(C)C[C@H](NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45)C(=O)NCC(c6ccccc6)c7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J08 compound treatment 125937.0 -439000.0 -2.61 226732.0 -189000.0 -1.08 -2.6075 -0.9233 3132115 CMLD2_000181 CO[C@H]1C[C@@H]2C[C@H](CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2)OC(=O)\C=C/CCc4coc(\C=C/CNC(=O)OC)n4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J09 compound treatment 629930.0 65300.0 0.39 187575.0 -228000.0 -1.3 -0.644 -0.4748 3011349 CMLD2_000182 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J10 compound treatment 605637.0 41000.0 0.24 505871.0 89800.0 0.51 0.5337 0.9429 3132116 CMLD2_000183 CO[C@@H](C(C)C)[C@@H](C)C1OC(=O)CC1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J11 compound treatment 478614.0 -86000.0 -0.51 216779.0 -199000.0 -1.13 -1.1634 -0.9355 3132117 CMLD2_000184 COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@](Oc3ccccc3C1=O)(C(=O)OC)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J12 compound treatment 495707.0 -68900.0 -0.41 224707.0 -191000.0 -1.09 -1.0596 -0.9111 3011350 CMLD2_000185 CC(=NOCc1cccc(c1)c2cc(no2)c3ccccc3)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J13 compound treatment 591156.0 26500.0 0.16 485631.0 69600.0 0.4 0.3913 0.9188 3132118 CMLD2_000186 CC(C)C(=O)N[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J14 compound treatment 620283.0 55700.0 0.33 216682.0 -199000.0 -1.13 -0.5676 -0.4805 3011352 CMLD2_000187 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C=C)cc2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J15 compound treatment 535897.0 -28700.0 -0.17 477037.0 61000.0 0.35 0.1242 0.3214 3132119 CMLD2_000188 CO[C@H](CO)COc1ccc(OC)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J16 compound treatment 397439.0 -167000.0 -1.0 230046.0 -186000.0 -1.06 -1.4516 -0.9995 3011353 CMLD2_000189 Oc1ccccc1C(=O)/C=C/c2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J17 compound treatment 604676.0 40000.0 0.24 172285.0 -244000.0 -1.39 -0.8118 -0.5771 3132120 CMLD2_000190 CC(=NOCc1ccc(cc1)c2cn(nn2)[C@@H]3COC[C@H]3O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J18 compound treatment 143011.0 -422000.0 -2.51 105552.0 -311000.0 -1.77 -3.0229 -0.9852 3011354 CMLD2_000191 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J19 compound treatment 484627.0 -80000.0 -0.48 433229.0 17200.0 0.1 -0.2677 -0.5507 3132121 CMLD2_000192 C[C@@H]1CC[C@@H]2N(CC(COCC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J20 compound treatment 208498.0 -356000.0 -2.12 495342.0 79300.0 0.45 -1.18 -0.5445 3011355 CMLD2_000193 CC(C)CCN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J21 mock treatment 565459.0 826.0 0.0 452435.0 36400.0 0.21 0.1497 0.7237 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J22 mock treatment 656297.0 91700.0 0.55 350706.0 -65400.0 -0.37 0.1229 0.1862 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J23 compound treatment 614674.0 50000.0 0.3 171072.0 -245000.0 -1.39 -0.7746 -0.5437 3132122 CMLD2_000194 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(Br)c3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5cccc(c5)N6CCOCC6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 J24 compound treatment 524270.0 -40400.0 -0.24 472030.0 56000.0 0.32 0.0552 0.1384 3132123 CMLD2_000195 CCC(=O)[C@@]1(O[C@@]23[C@H]4[C@@H]1CCOC4=O)C(=O)N3[C@@H](C(=C(C)N2Cc5ccccc5)C(=O)OC)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K01 compound treatment 468407.0 -96200.0 -0.57 562615.0 147000.0 0.83 0.1843 0.1823 3132124 CMLD2_000196 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K02 compound treatment 247848.0 -317000.0 -1.89 530078.0 114000.0 0.65 -0.8747 -0.4387 3011357 CMLD2_000197 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K03 compound treatment 401870.0 -163000.0 -0.97 482421.0 66400.0 0.38 -0.4181 -0.4022 3132125 CMLD2_000198 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K04 compound treatment 83441.0 -481000.0 -2.86 68579.0 -347000.0 -1.98 -3.4223 -0.9836 3132126 CMLD2_000199 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCCc6ccc(F)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K05 compound treatment 642186.0 77600.0 0.46 522958.0 107000.0 0.61 0.7562 0.9908 3011359 CMLD2_000200 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K06 compound treatment 126443.0 -438000.0 -2.61 130745.0 -285000.0 -1.62 -2.9914 -0.9739 3132127 CMLD2_000201 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K07 mock treatment 118937.0 -446000.0 -2.65 513770.0 97700.0 0.56 -1.4827 -0.5471 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K08 mock treatment 620667.0 56000.0 0.33 512983.0 96900.0 0.55 0.6255 0.971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K09 compound treatment 719065.0 154000.0 0.92 557276.0 141000.0 0.8 1.2177 0.9977 3011360 CMLD2_000202 COc1cccc(c1)[C@H](O)Cn2cc(nn2)c3ccc(CON=C(C)C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K10 compound treatment 746080.0 181000.0 1.08 486761.0 70700.0 0.4 1.0478 0.9094 3132128 CMLD2_000203 Cc1ccc2[nH]c3nc(CCCn4ccnc4c5ccccc5)nnc3c2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K11 compound treatment 634940.0 70300.0 0.42 499362.0 83300.0 0.47 0.6308 0.9981 3011361 CMLD2_000204 COC(=O)C1=C(C)[C@@H](O)[C@@H](C)[C@@H](O1)c2c(OC)c(OC)c(C)c(OC)c2OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K12 compound treatment 79411.0 -485000.0 -2.89 71417.0 -345000.0 -1.96 -3.4278 -0.9822 3132129 CMLD2_000205 C[C@H]1OC=C2[C@H](OC(=O)C)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](O)[C@H]7O[C@H]7C6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K13 compound treatment 558089.0 -6540.0 -0.04 493362.0 77300.0 0.44 0.2833 0.6419 3011362 CMLD2_000206 CO[C@H]1C[C@@H]2C[C@H](O)CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K14 compound treatment 455317.0 -109000.0 -0.65 538307.0 122000.0 0.7 0.0315 0.0331 3011258 CMLD2_000207 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K15 mock treatment 581932.0 17300.0 0.1 482115.0 66000.0 0.38 0.3384 0.8689 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K16 mock treatment 583571.0 18900.0 0.11 487633.0 71600.0 0.41 0.3675 0.8702 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K17 compound treatment 50124.0 -515000.0 -3.06 68354.0 -348000.0 -1.98 -3.5634 -0.9776 3132248 CMLD2_000208 CCN1C(=O)[C@H]2CC=C3[C@H]([C@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C53OCCCO5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K18 compound treatment 528933.0 -35700.0 -0.21 377029.0 -39000.0 -0.22 -0.3072 -0.9998 3011363 CMLD2_000209 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K19 compound treatment 562654.0 -1980.0 -0.01 455595.0 39500.0 0.22 0.1506 0.6691 3132249 CMLD2_000210 C[C@@H]1CC[C@@H]2N(CC(COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K20 compound treatment 580620.0 16000.0 0.1 501669.0 85600.0 0.49 0.4115 0.8296 3011399 CMLD2_000211 CCCCc1nc2CCN(CCC(C)C)Cc2c3CO[C@@H](C)Cc13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K21 compound treatment 559102.0 -5530.0 -0.03 289483.0 -127000.0 -0.72 -0.5323 -0.7387 3132250 CMLD2_000212 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K22 compound treatment 633096.0 68500.0 0.41 497792.0 81700.0 0.46 0.6167 0.9979 3011400 CMLD2_000213 C[C@@H]1CC[C@H](N[C@H]1c2ccc(cc2)c3ccco3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K23 mock treatment 624827.0 60200.0 0.36 573681.0 158000.0 0.9 0.8871 0.919 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 K24 mock treatment 575083.0 10500.0 0.06 410669.0 -5400.0 -0.03 0.0223 0.3209 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L01 compound treatment 219669.0 -345000.0 -2.05 448601.0 32500.0 0.18 -1.3209 -0.6408 3132251 CMLD2_000214 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L02 compound treatment 528498.0 -36100.0 -0.22 490079.0 74000.0 0.42 0.1455 0.3079 3132252 CMLD2_000215 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L03 compound treatment 613114.0 48500.0 0.29 482959.0 66900.0 0.38 0.473 0.9907 3011402 CMLD2_000216 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L04 compound treatment 204581.0 -360000.0 -2.14 318123.0 -97900.0 -0.56 -1.9091 -0.8623 3132253 CMLD2_000217 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L05 compound treatment 629724.0 65100.0 0.39 483856.0 67800.0 0.39 0.5465 1.0 3132254 CMLD2_000218 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L06 compound treatment 205823.0 -359000.0 -2.14 456110.0 40000.0 0.23 -1.349 -0.6281 3011403 CMLD2_000219 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L07 mock treatment 212677.0 -352000.0 -2.09 538283.0 122000.0 0.69 -0.9897 -0.4484 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L08 mock treatment 673857.0 109000.0 0.65 479066.0 63000.0 0.36 0.713 0.9606 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L09 compound treatment 427773.0 -137000.0 -0.81 323437.0 -92600.0 -0.53 -0.9484 -0.9778 3132255 CMLD2_000220 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L10 compound treatment 675625.0 111000.0 0.66 467937.0 51900.0 0.29 0.6757 0.934 3132256 CMLD2_000221 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(C)c(C)cc45)CCCc3n2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L11 compound treatment 638464.0 73800.0 0.44 532093.0 116000.0 0.66 0.7773 0.9805 3011404 CMLD2_000222 CCOC(=O)C1=NO[C@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L12 compound treatment 605089.0 40500.0 0.24 504538.0 88500.0 0.5 0.526 0.9431 3011405 CMLD2_000223 OC(CCc1ccccc1)C2=CCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L13 compound treatment 597555.0 32900.0 0.2 521256.0 105000.0 0.6 0.5615 0.8921 3132257 CMLD2_000224 OC(CCc1ccccc1)C23OC3CCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L14 compound treatment 548544.0 -16100.0 -0.1 297786.0 -118000.0 -0.67 -0.5433 -0.7997 3132258 CMLD2_000225 CCCNC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L15 mock treatment 597573.0 32900.0 0.2 492114.0 76000.0 0.43 0.4444 0.936 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L16 mock treatment 609607.0 45000.0 0.27 455416.0 39300.0 0.22 0.3475 0.996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L17 compound treatment 585222.0 20600.0 0.12 234519.0 -182000.0 -1.03 -0.6434 -0.6188 3011407 CMLD2_000226 C[C@H]1CC[C@@H]2N([C@@H]1c3ccccc3)C(=O)[C@@H](Cc4ccccc4)NC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L18 compound treatment 76123.0 -489000.0 -2.91 54039.0 -362000.0 -2.06 -3.5116 -0.9857 3132259 CMLD2_000227 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L19 compound treatment 634903.0 70300.0 0.42 464483.0 48400.0 0.28 0.4904 0.9794 3132260 CMLD2_000228 C[C@@H]1CC[C@@H]2N(CC(CN3C(=O)c4ccccc4C3=O)OC2=O)[C@H]1c5ccc(Br)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L20 compound treatment 621211.0 56600.0 0.34 418094.0 2020.0 0.01 0.2462 0.7309 3011408 CMLD2_000229 CC(C)CCN1CCc2nc(COc3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L21 compound treatment 158001.0 -407000.0 -2.42 98524.0 -318000.0 -1.81 -2.9881 -0.9896 3132261 CMLD2_000230 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L22 compound treatment 631833.0 67200.0 0.4 495289.0 79200.0 0.45 0.6014 0.9982 3011409 CMLD2_000231 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#CCN(C)C)cc2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L23 mock treatment 656012.0 91400.0 0.54 522424.0 106000.0 0.6 0.8122 0.9986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 L24 mock treatment 626897.0 62300.0 0.37 492193.0 76100.0 0.43 0.5681 0.997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M01 compound treatment 73941.0 -491000.0 -2.92 75396.0 -341000.0 -1.94 -3.4349 -0.9801 3132262 CMLD2_000232 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc4ccccc34)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M02 compound treatment 620711.0 56100.0 0.33 566381.0 150000.0 0.85 0.8404 0.9159 3132263 CMLD2_000233 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M03 compound treatment 379491.0 -185000.0 -1.1 310675.0 -105000.0 -0.6 -1.2029 -0.959 3011410 CMLD2_000234 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M04 compound treatment 579248.0 14600.0 0.09 461341.0 45300.0 0.26 0.2435 0.8962 3132264 CMLD2_000235 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M05 compound treatment 83314.0 -481000.0 -2.86 64600.0 -351000.0 -2.0 -3.4388 -0.9845 3132265 CMLD2_000236 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M06 compound treatment 623040.0 58400.0 0.35 513243.0 97200.0 0.55 0.6365 0.975 3011411 CMLD2_000237 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M07 compound treatment 82142.0 -482000.0 -2.87 68607.0 -347000.0 -1.98 -3.4277 -0.9834 3132266 CMLD2_000238 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccncc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M08 compound treatment 603133.0 38500.0 0.23 503508.0 87400.0 0.5 0.5136 0.9381 3011412 CMLD2_000239 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M09 mock treatment 638669.0 74000.0 0.44 485851.0 69800.0 0.4 0.5922 0.9986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M10 mock treatment 514188.0 -50400.0 -0.3 495262.0 79200.0 0.45 0.1062 0.1961 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M11 compound treatment 661794.0 97200.0 0.58 480249.0 64200.0 0.36 0.667 0.9754 3132389 CMLD2_000240 COC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M12 compound treatment 533611.0 -31000.0 -0.18 528596.0 113000.0 0.64 0.3219 0.4834 3011413 CMLD2_000241 O=C1CCCC(C1)C2=CCCCC2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M13 mock treatment 602536.0 37900.0 0.23 501514.0 85400.0 0.49 0.5031 0.9391 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M14 mock treatment 300744.0 -264000.0 -1.57 499258.0 83200.0 0.47 -0.776 -0.4731 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M15 compound treatment 540949.0 -23700.0 -0.14 521001.0 105000.0 0.6 0.3223 0.5256 3132390 CMLD2_000242 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCCc2nc1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M16 compound treatment 660599.0 96000.0 0.57 569397.0 153000.0 0.87 1.0204 0.979 3011415 CMLD2_000243 CCO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M17 mock treatment 592370.0 27700.0 0.17 481170.0 65100.0 0.37 0.3785 0.9338 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M18 compound treatment 69657.0 -495000.0 -2.95 69780.0 -346000.0 -1.97 -3.4755 -0.9808 3132391 CMLD2_000244 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCC2CCCCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M19 compound treatment 615010.0 50400.0 0.3 521866.0 106000.0 0.6 0.6374 0.9483 3132392 CMLD2_000245 C[C@@H]1CC[C@@H]2N(CC(Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M20 compound treatment 646556.0 81900.0 0.49 456566.0 40500.0 0.23 0.5076 0.9414 3011466 CMLD2_000246 COc1ccc(cc1)c2nc3CCN(CCC(C)C)Cc3c4CO[C@@H](C)Cc24 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M21 compound treatment 655471.0 90800.0 0.54 442564.0 26500.0 0.15 0.4888 0.871 3132393 CMLD2_000247 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCOC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M22 compound treatment 569644.0 5010.0 0.03 448015.0 31900.0 0.18 0.1495 0.8123 3011467 CMLD2_000248 C[C@H]1CC[C@H](N[C@@H]1c2cccc(c2)N3CCCC3=O)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M23 compound treatment 608599.0 44000.0 0.26 498704.0 82600.0 0.47 0.5173 0.9618 3132394 CMLD2_000249 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 M24 compound treatment 107250.0 -457000.0 -2.72 151527.0 -265000.0 -1.5 -2.9886 -0.9609 3132261 CMLD2_000250 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N01 compound treatment 110516.0 -454000.0 -2.7 105200.0 -311000.0 -1.77 -3.1611 -0.9788 3132395 CMLD2_000251 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N02 compound treatment 555644.0 -8990.0 -0.05 505426.0 89400.0 0.51 0.3215 0.6292 3132396 CMLD2_000252 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N03 compound treatment 607549.0 42900.0 0.26 326040.0 -90000.0 -0.51 -0.1814 -0.3171 3011471 CMLD2_000253 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N04 compound treatment 78162.0 -486000.0 -2.9 84187.0 -332000.0 -1.89 -3.3818 -0.9785 3132397 CMLD2_000254 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N05 compound treatment 378469.0 -186000.0 -1.11 327539.0 -88500.0 -0.5 -1.1394 -0.9363 3011472 CMLD2_000255 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N06 compound treatment 587455.0 22800.0 0.14 215940.0 -200000.0 -1.14 -0.7087 -0.6183 3132398 CMLD2_000256 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N07 compound treatment 597352.0 32700.0 0.19 507396.0 91300.0 0.52 0.5049 0.9103 3132399 CMLD2_000257 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccc5OCOc5c4)O3)O2)OC(=O)NCc6cccc7ccccc67 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N08 compound treatment 590075.0 25400.0 0.15 295777.0 -120000.0 -0.68 -0.3766 -0.5376 3011473 CMLD2_000258 Cc1ccc(cc1)S(=O)(=O)n2c3ccccc3c4nnc(nc24)C(=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N09 mock treatment 580492.0 15900.0 0.09 185591.0 -230000.0 -1.31 -0.86 -0.6545 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N10 mock treatment 656314.0 91700.0 0.55 519340.0 103000.0 0.59 0.8011 0.9993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N11 compound treatment 562840.0 -1790.0 -0.01 461351.0 45300.0 0.26 0.1745 0.6772 3011475 CMLD2_000259 BrC1=CC(=C)[C@@H]2O[C@@H]2C31OCCCO3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N12 compound treatment 136151.0 -428000.0 -2.55 176229.0 -240000.0 -1.36 -2.7676 -0.957 3132400 CMLD2_000260 CCCCOC(OCCCC)C(O)CSc1ccc2ccccc2c1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N13 mock treatment 627977.0 63300.0 0.38 524629.0 109000.0 0.62 0.7031 0.972 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N14 mock treatment 601342.0 36700.0 0.22 542032.0 126000.0 0.72 0.661 0.8826 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N15 compound treatment 89161.0 -475000.0 -2.83 57993.0 -358000.0 -2.04 -3.4408 -0.987 3011477 CMLD2_000261 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N16 compound treatment 72837.0 -492000.0 -2.93 73950.0 -342000.0 -1.95 -3.4453 -0.9803 3132401 CMLD2_000262 CO[C@@H](C(C)C)[C@@H](C)C1OC1CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N17 compound treatment 78404.0 -486000.0 -2.89 65530.0 -351000.0 -1.99 -3.4558 -0.9835 4845 CMLD2_000263 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(O[C@]2([C@@H]1c4ccccc4)c5ccc(OC)cc5)cc(OC)cc3OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N18 compound treatment 209723.0 -355000.0 -2.11 128272.0 -288000.0 -1.64 -2.6508 -0.992 3011479 CMLD2_000264 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2cc(OC)c(OC)c(OC)c2)C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N19 compound treatment 648699.0 84100.0 0.5 525303.0 109000.0 0.62 0.793 0.9942 3132403 CMLD2_000265 C[C@H]1CC[C@@H]2N(CC(COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N20 compound treatment 667664.0 103000.0 0.61 503371.0 87300.0 0.5 0.7846 0.9945 3011480 CMLD2_000266 C[C@H]1Cc2c(nc3CCN(CCOc4ccccc4)Cc3c2CO1)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N21 compound treatment 497280.0 -67400.0 -0.4 407770.0 -8300.0 -0.05 -0.3168 -0.7849 3132404 CMLD2_000267 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N22 compound treatment 570256.0 5620.0 0.03 510051.0 94000.0 0.53 0.4016 0.7499 3011481 CMLD2_000268 C[C@@H]1CC[C@H](N[C@H]1c2ccc(NC(=O)C)cc2)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N23 compound treatment 610540.0 45900.0 0.27 453448.0 37400.0 0.21 0.3435 0.9923 3132405 CMLD2_000269 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@H](C(C)C)N(C)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 N24 compound treatment 587910.0 23300.0 0.14 407781.0 -8290.0 -0.05 0.0646 0.4417 3131577 CMLD2_000270 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O01 compound treatment 394327.0 -170000.0 -1.01 484764.0 68700.0 0.39 -0.4405 -0.4055 3132406 CMLD2_000271 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O02 compound treatment 81759.0 -483000.0 -2.87 79903.0 -336000.0 -1.91 -3.3838 -0.9804 3132407 CMLD2_000272 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6ccc7OCOc7c6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O03 compound treatment 487086.0 -77500.0 -0.46 460642.0 44600.0 0.25 -0.1471 -0.2794 3011482 CMLD2_000273 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O04 compound treatment 105698.0 -459000.0 -2.73 114817.0 -301000.0 -1.71 -3.1427 -0.9747 3132527 CMLD2_000274 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O05 compound treatment 475904.0 -88700.0 -0.53 386928.0 -29100.0 -0.17 -0.4906 -0.8864 3011483 CMLD2_000275 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O06 compound treatment 565300.0 667.0 0.0 535751.0 120000.0 0.68 0.4841 0.7112 3132528 CMLD2_000276 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O07 compound treatment 474986.0 -89600.0 -0.53 441135.0 25100.0 0.14 -0.2765 -0.5006 3011485 CMLD2_000277 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O08 compound treatment 460041.0 -105000.0 -0.62 186534.0 -230000.0 -1.31 -1.3631 -0.9426 3132529 CMLD2_000278 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O09 compound treatment 677835.0 113000.0 0.67 547177.0 131000.0 0.75 1.0036 0.9987 3011486 CMLD2_000279 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H](O)[C@H]1C)c2c(OC)c(OC)c(C)c(OC)c2OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O10 compound treatment 76282.0 -488000.0 -2.91 52305.0 -364000.0 -2.07 -3.5179 -0.9861 3132530 CMLD2_000280 OC(CCCCBr)C1=CCCCC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O11 mock treatment 155796.0 -409000.0 -2.43 163202.0 -253000.0 -1.44 -2.7373 -0.9685 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O12 mock treatment 339978.0 -225000.0 -1.34 278796.0 -137000.0 -0.78 -1.4974 -0.9672 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O13 compound treatment 561186.0 -3450.0 -0.02 525720.0 110000.0 0.62 0.4264 0.6835 3132531 CMLD2_000281 COC(=O)C/C=C/[C@H](C)[C@@H](OCc1ccccc1Br)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O14 compound treatment 61264.0 -503000.0 -3.0 61382.0 -355000.0 -2.02 -3.5446 -0.9815 3011535 CMLD2_000282 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O15 compound treatment 180284.0 -384000.0 -2.29 227338.0 -189000.0 -1.07 -2.3764 -0.9405 3132532 CMLD2_000283 Nc1ccccc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O16 compound treatment 596561.0 31900.0 0.19 584247.0 168000.0 0.96 0.8106 0.8313 3131858 CMLD2_000284 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O17 mock treatment 516558.0 -48100.0 -0.29 444951.0 28900.0 0.16 -0.0862 -0.2612 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O18 compound treatment 81631.0 -483000.0 -2.87 72595.0 -343000.0 -1.95 -3.4138 -0.9823 3011536 CMLD2_000285 OC[C@H]1O[C@@H](C=C[C@@H]1O)C#Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O19 compound treatment 479145.0 -85500.0 -0.51 489663.0 73600.0 0.42 -0.0638 -0.0969 3132533 CMLD2_000286 C[C@H]1CC[C@@H]2N(C[C@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O20 compound treatment 528170.0 -36500.0 -0.22 423098.0 7030.0 0.04 -0.1252 -0.5673 3011537 CMLD2_000287 C[C@H]1Cc2c(COc3ccccc3)nc4CCN(CCOc5ccccc5)Cc4c2CO1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O21 compound treatment 640308.0 75700.0 0.45 484201.0 68100.0 0.39 0.5924 0.9972 3132534 CMLD2_000288 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O22 compound treatment 582716.0 18100.0 0.11 496818.0 80700.0 0.46 0.4008 0.8498 3011538 CMLD2_000289 C[C@@H]1CC[C@H](N[C@H]1c2cccc(c2)N3CCOCC3)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O23 compound treatment 537282.0 -27400.0 -0.16 480510.0 64400.0 0.37 0.144 0.3592 3132535 CMLD2_000290 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)c3ccccc3)c4ccccc4)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 O24 compound treatment 571246.0 6610.0 0.04 497266.0 81200.0 0.46 0.3543 0.7646 3132250 CMLD2_000291 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P01 compound treatment 100663.0 -464000.0 -2.76 104966.0 -311000.0 -1.77 -3.2035 -0.9769 3132536 CMLD2_000292 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P02 compound treatment 403877.0 -161000.0 -0.96 374293.0 -41800.0 -0.24 -0.8445 -0.8567 3132537 CMLD2_000293 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P03 compound treatment 575238.0 10600.0 0.06 428282.0 12200.0 0.07 0.0937 0.9989 3011540 CMLD2_000294 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P04 compound treatment 590569.0 25900.0 0.15 477400.0 61300.0 0.35 0.3558 0.9328 3132538 CMLD2_000295 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P05 compound treatment 25934.0 -539000.0 -3.21 71010.0 -345000.0 -1.96 -3.6545 -0.9722 3011541 CMLD2_000296 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P06 compound treatment 119629.0 -445000.0 -2.65 108857.0 -307000.0 -1.75 -3.108 -0.9796 3132539 CMLD2_000297 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P07 compound treatment 572701.0 8070.0 0.05 479149.0 63100.0 0.36 0.2876 0.7947 3011542 CMLD2_000298 CCN(CC)CC(O)CN1CCCCc2nc(C)c(C)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P08 compound treatment 601960.0 37300.0 0.22 474242.0 58200.0 0.33 0.391 0.9812 3131847 CMLD2_000299 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P09 compound treatment 308876.0 -256000.0 -1.52 301019.0 -115000.0 -0.65 -1.5389 -0.9289 3132540 CMLD2_000300 C[C@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5O[C@H](C)[C@@H]([C@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P10 compound treatment 65391.0 -499000.0 -2.97 74225.0 -342000.0 -1.94 -3.4756 -0.9789 3011543 CMLD2_000301 COCOc1ccc(Br)cc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P11 mock treatment 597712.0 33100.0 0.2 183922.0 -232000.0 -1.32 -0.7943 -0.5951 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P12 mock treatment 605549.0 40900.0 0.24 453060.0 37000.0 0.21 0.3209 0.9973 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P13 compound treatment 631656.0 67000.0 0.4 204359.0 -212000.0 -1.2 -0.5693 -0.4488 3132541 CMLD2_000302 COC(OC)[C@@H](C)[C@H](OC)[C@@H](C)[C@H](OC)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P14 compound treatment 607330.0 42700.0 0.25 507433.0 91400.0 0.52 0.5471 0.9459 3011544 CMLD2_000303 CC(C)c1ccc(C)n1C(=O)OC(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P15 compound treatment 584764.0 20100.0 0.12 479991.0 63900.0 0.36 0.3418 0.8929 3011545 CMLD2_000304 Brc1ccc(cc1)[C@@H]2OC(=O)C[C@@H]2c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P16 compound treatment 578295.0 13700.0 0.08 499107.0 83000.0 0.47 0.3914 0.8168 3132542 CMLD2_000305 COC(=O)[C@H]1[C@@H](C(=O)[C@]2(O)c3ccccc3O[C@@]12c4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P17 mock treatment 503264.0 -61400.0 -0.37 479779.0 63700.0 0.36 -0.0021 -0.004 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P18 compound treatment 450521.0 -114000.0 -0.68 431420.0 15400.0 0.09 -0.4185 -0.6112 3132543 CMLD2_000306 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P19 compound treatment 537848.0 -26800.0 -0.16 522129.0 106000.0 0.6 0.3138 0.503 3011546 CMLD2_000307 C[C@@H]1CCC2N(C[C@H](O)CN(Cc3ccccc3)C2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P20 compound treatment 540004.0 -24600.0 -0.15 451547.0 35500.0 0.2 0.039 0.1565 3132544 CMLD2_000308 CCCCc1nc2CCN(CCOc3ccccc3)Cc2c4CO[C@@H](C)Cc14 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P21 compound treatment 645343.0 80700.0 0.48 505448.0 89400.0 0.51 0.6991 0.9996 3131978 CMLD2_000309 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P22 compound treatment 589103.0 24500.0 0.15 487772.0 71700.0 0.41 0.3913 0.9037 3011547 CMLD2_000310 COCC#Cc1ccc(cc1)[C@@H]2N[C@@H](CC[C@H]2C)C(=O)O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P23 compound treatment 607403.0 42800.0 0.25 534471.0 118000.0 0.67 0.6561 0.9115 3132545 CMLD2_000311 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@@H]4CC[C@H](C)[C@H](N4C3=O)c5cccc(OC)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2109 P24 compound treatment 616349.0 51700.0 0.31 456048.0 40000.0 0.23 0.3784 0.9889 3132534 CMLD2_000312 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A01 compound treatment 434872.0 -4380.0 -0.03 283800.0 -168000.0 -0.96 -0.695 -0.7261 3132546 CMLD2_000313 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A02 compound treatment 532021.0 92800.0 0.55 502322.0 50300.0 0.29 0.5926 0.9531 3011548 CMLD2_000314 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A03 compound treatment 499507.0 60300.0 0.36 363654.0 -88400.0 -0.5 -0.1018 -0.1649 3130471 CMLD2_000315 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A04 compound treatment 471475.0 32200.0 0.19 434373.0 -17700.0 -0.1 0.0646 0.2982 3130472 CMLD2_000316 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A05 compound treatment 140781.0 -298000.0 -1.78 212395.0 -240000.0 -1.36 -2.2197 -0.9914 3011549 CMLD2_000317 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A06 compound treatment 441738.0 2490.0 0.01 521729.0 69700.0 0.4 0.2907 0.733 3011597 CMLD2_000318 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A07 compound treatment 484281.0 45000.0 0.27 491348.0 39300.0 0.22 0.3476 0.9959 3130473 CMLD2_000319 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A08 compound treatment 361064.0 -78200.0 -0.47 519352.0 67300.0 0.38 -0.0584 -0.0969 3010878 CMLD2_000320 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A09 compound treatment 340615.0 -98600.0 -0.59 36688.0 -415000.0 -2.36 -2.0853 -0.8568 3130474 CMLD2_000321 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A10 compound treatment 326635.0 -113000.0 -0.67 503055.0 51000.0 0.29 -0.2688 -0.368 3010879 CMLD2_000322 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A11 compound treatment 405684.0 -33600.0 -0.2 508556.0 56500.0 0.32 0.086 0.2272 3130475 CMLD2_000323 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A12 compound treatment 431562.0 -7690.0 -0.05 532241.0 80200.0 0.46 0.2901 0.633 3130476 CMLD2_000324 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A13 mock treatment 360780.0 -78500.0 -0.47 507212.0 55200.0 0.31 -0.1084 -0.1926 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A14 mock treatment 401910.0 -37300.0 -0.22 530527.0 78500.0 0.45 0.1585 0.3178 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A15 compound treatment 446146.0 6890.0 0.04 508575.0 56500.0 0.32 0.2563 0.7909 3010880 CMLD2_000325 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A16 compound treatment 396979.0 -42300.0 -0.25 483108.0 31100.0 0.18 -0.053 -0.1723 3130477 CMLD2_000326 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A17 compound treatment 74040.0 -365000.0 -2.17 75565.0 -376000.0 -2.14 -3.0508 -1.0 3010881 CMLD2_000327 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A18 compound treatment 180467.0 -259000.0 -1.54 498056.0 46000.0 0.26 -0.904 -0.5787 3130478 CMLD2_000328 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A19 compound treatment 274974.0 -164000.0 -0.98 368860.0 -83200.0 -0.47 -1.0258 -0.9445 3130479 CMLD2_000329 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A20 compound treatment 490981.0 51700.0 0.31 292043.0 -160000.0 -0.91 -0.4257 -0.4432 3010882 CMLD2_000330 C[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H](C)NC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A21 compound treatment 323849.0 -115000.0 -0.69 499383.0 47300.0 0.27 -0.2953 -0.4003 3130480 CMLD2_000331 C[C@H]/1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C\C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A22 compound treatment 486086.0 46800.0 0.28 504947.0 52900.0 0.3 0.4098 0.9993 3010883 CMLD2_000332 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc3ccccc3)\C=C\[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A23 compound treatment 356245.0 -83000.0 -0.49 583199.0 131000.0 0.75 0.1781 0.1991 3130481 CMLD2_000333 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 A24 compound treatment 534541.0 95300.0 0.57 509293.0 57300.0 0.33 0.6312 0.9653 3130482 CMLD2_000334 C[C@@H]1/C=C/CC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2O)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B01 compound treatment 562271.0 123000.0 0.73 528326.0 76300.0 0.43 0.8245 0.9688 3010884 CMLD2_000335 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B02 compound treatment 484927.0 45700.0 0.27 577861.0 126000.0 0.72 0.6982 0.9121 3130483 CMLD2_000336 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B03 compound treatment 335020.0 -104000.0 -0.62 415301.0 -36700.0 -0.21 -0.5864 -0.8958 3130484 CMLD2_000337 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B04 compound treatment 558943.0 120000.0 0.71 499124.0 47100.0 0.27 0.693 0.9107 3010885 CMLD2_000338 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B05 compound treatment 291236.0 -148000.0 -0.88 507656.0 55600.0 0.32 -0.3993 -0.4266 3130485 CMLD2_000339 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B06 compound treatment 221026.0 -218000.0 -1.3 486895.0 34900.0 0.2 -0.7782 -0.5923 3010886 CMLD2_000340 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B07 compound treatment 447397.0 8150.0 0.05 531071.0 79000.0 0.45 0.3521 0.7789 3130486 CMLD2_000341 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B08 compound treatment 505680.0 66400.0 0.4 549247.0 97200.0 0.55 0.6704 0.9865 3130487 CMLD2_000342 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B09 compound treatment 117856.0 -321000.0 -1.91 256648.0 -195000.0 -1.11 -2.1382 -0.9666 3010887 CMLD2_000343 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B10 compound treatment 17119.0 -422000.0 -2.51 165369.0 -287000.0 -1.63 -2.9292 -0.9781 3130488 CMLD2_000344 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B11 compound treatment 135472.0 -304000.0 -1.81 498399.0 46400.0 0.26 -1.092 -0.5977 3010888 CMLD2_000345 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B12 compound treatment 239227.0 -200000.0 -1.19 463517.0 11500.0 0.07 -0.7956 -0.6673 3130489 CMLD2_000346 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B13 mock treatment 479510.0 40300.0 0.24 483037.0 31000.0 0.18 0.2941 0.9886 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B14 mock treatment 299380.0 -140000.0 -0.83 492753.0 40700.0 0.23 -0.4249 -0.4918 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B15 compound treatment 66157.0 -373000.0 -2.22 72314.0 -380000.0 -2.16 -3.097 -0.9999 3130616 CMLD2_000347 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCc6ccccc6)n3c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B16 compound treatment 245847.0 -193000.0 -1.15 426142.0 -25900.0 -0.15 -0.918 -0.7911 3010889 CMLD2_000348 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B17 compound treatment 71634.0 -368000.0 -2.19 81711.0 -370000.0 -2.11 -3.0362 -0.9998 3130617 CMLD2_000349 CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B18 compound treatment 201695.0 -238000.0 -1.41 450713.0 -1330.0 -0.01 -1.005 -0.7109 3010924 CMLD2_000350 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B19 compound treatment 447020.0 7770.0 0.05 397585.0 -54500.0 -0.31 -0.1863 -0.595 3130618 CMLD2_000351 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B20 compound treatment 473235.0 34000.0 0.2 434843.0 -17200.0 -0.1 0.0739 0.3288 3130619 CMLD2_000352 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B21 compound treatment 194675.0 -245000.0 -1.46 462565.0 10500.0 0.06 -0.9869 -0.6775 3010926 CMLD2_000353 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B22 compound treatment 476974.0 37700.0 0.22 432594.0 -19400.0 -0.11 0.0805 0.3219 3130620 CMLD2_000354 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B23 compound treatment 406605.0 -32600.0 -0.19 585538.0 133000.0 0.76 0.3994 0.5097 3130621 CMLD2_000355 C[C@@H]/1COC(=O)N[C@@H](C)C(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 B24 compound treatment 402153.0 -37100.0 -0.22 537520.0 85500.0 0.49 0.1876 0.3514 3010928 CMLD2_000356 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]3O[C@H](COC1=O)[C@@H](O)C=C3)[C@@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C01 compound treatment 448445.0 9190.0 0.05 410219.0 -41800.0 -0.24 -0.1295 -0.5306 3130622 CMLD2_000357 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C02 compound treatment 261097.0 -178000.0 -1.06 524007.0 72000.0 0.41 -0.4603 -0.405 3130623 CMLD2_000358 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C03 compound treatment 478036.0 38800.0 0.23 496897.0 44900.0 0.26 0.3436 0.9988 3010930 CMLD2_000359 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C04 compound treatment 469353.0 30100.0 0.18 522852.0 70800.0 0.4 0.4114 0.9335 3130624 CMLD2_000360 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C05 compound treatment 472394.0 33100.0 0.2 376930.0 -75100.0 -0.43 -0.1626 -0.3455 3010931 CMLD2_000361 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C06 compound treatment 443953.0 4700.0 0.03 371029.0 -81000.0 -0.46 -0.306 -0.6629 3130625 CMLD2_000362 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C07 compound treatment 437553.0 -1700.0 -0.01 487534.0 35500.0 0.2 0.1356 0.6708 3130626 CMLD2_000363 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C08 compound treatment 425607.0 -13600.0 -0.08 269836.0 -182000.0 -1.04 -0.7901 -0.7602 3010932 CMLD2_000364 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C09 compound treatment 446935.0 7680.0 0.05 223960.0 -228000.0 -1.3 -0.8848 -0.6818 3130627 CMLD2_000365 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C10 compound treatment 529241.0 90000.0 0.54 331926.0 -120000.0 -0.68 -0.1043 -0.1202 3010933 CMLD2_000366 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C11 mock treatment 399562.0 -39700.0 -0.24 374221.0 -77800.0 -0.44 -0.4799 -0.9568 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C12 mock treatment 508449.0 69200.0 0.41 237733.0 -214000.0 -1.22 -0.5706 -0.4435 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C13 compound treatment 421238.0 -18000.0 -0.11 75378.0 -377000.0 -2.14 -1.5904 -0.7416 3130628 CMLD2_000367 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C14 compound treatment 389097.0 -50200.0 -0.3 459612.0 7570.0 0.04 -0.1806 -0.5989 3010934 CMLD2_000368 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C15 mock treatment 415880.0 -23400.0 -0.14 225923.0 -226000.0 -1.29 -1.0076 -0.7791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C16 mock treatment 428678.0 -10600.0 -0.06 440425.0 -11600.0 -0.07 -0.0912 -0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C17 compound treatment 428081.0 -11200.0 -0.07 438891.0 -13100.0 -0.07 -0.0999 -0.9983 3130629 CMLD2_000369 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C18 compound treatment 227899.0 -211000.0 -1.26 453062.0 1020.0 0.01 -0.8853 -0.7038 3130630 CMLD2_000370 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C19 compound treatment 439445.0 193.0 0.0 421790.0 -30300.0 -0.17 -0.1208 -0.7024 3010935 CMLD2_000371 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C20 compound treatment 403378.0 -35900.0 -0.21 467742.0 15700.0 0.09 -0.0878 -0.3795 3130631 CMLD2_000372 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C21 compound treatment 508054.0 68800.0 0.41 399075.0 -53000.0 -0.3 0.0766 0.1506 3010936 CMLD2_000373 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C22 compound treatment 478488.0 39200.0 0.23 437054.0 -15000.0 -0.09 0.1049 0.4218 3130632 CMLD2_000374 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C23 compound treatment 468468.0 29200.0 0.17 529918.0 77900.0 0.44 0.4361 0.9166 3130633 CMLD2_000375 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 C24 compound treatment 426849.0 -12400.0 -0.07 525824.0 73800.0 0.42 0.2445 0.5739 3010937 CMLD2_000376 C[C@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D01 compound treatment 527395.0 88100.0 0.52 551873.0 99800.0 0.57 0.7724 0.9992 3130634 CMLD2_000377 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D02 compound treatment 425699.0 -13600.0 -0.08 471788.0 19700.0 0.11 0.0224 0.1618 3010938 CMLD2_000378 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D03 compound treatment 439292.0 40.0 0.0 485707.0 33700.0 0.19 0.1355 0.708 3130635 CMLD2_000379 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D04 compound treatment 464498.0 25200.0 0.15 531061.0 79000.0 0.45 0.424 0.8948 3130759 CMLD2_000380 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D05 compound treatment 470664.0 31400.0 0.19 306351.0 -146000.0 -0.83 -0.4536 -0.5341 3010939 CMLD2_000381 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D06 compound treatment 499521.0 60300.0 0.36 418825.0 -33200.0 -0.19 0.1201 0.2962 3130760 CMLD2_000382 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D07 compound treatment 452841.0 13600.0 0.08 473813.0 21800.0 0.12 0.1447 0.9787 3130761 CMLD2_000383 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D08 compound treatment 449128.0 9880.0 0.06 485436.0 33400.0 0.19 0.1759 0.8846 3130762 CMLD2_000384 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D09 compound treatment 473287.0 34000.0 0.2 505124.0 53100.0 0.3 0.3567 0.9812 3010981 CMLD2_000385 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D10 compound treatment 452406.0 13200.0 0.08 504926.0 52900.0 0.3 0.268 0.8624 3130763 CMLD2_000386 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D11 mock treatment 194927.0 -244000.0 -1.45 481412.0 29400.0 0.17 -0.9101 -0.6218 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D12 mock treatment 469310.0 30100.0 0.18 429712.0 -22300.0 -0.13 0.0367 0.1673 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D13 compound treatment 452835.0 13600.0 0.08 429684.0 -22400.0 -0.13 -0.0327 -0.2173 3130764 CMLD2_000387 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D14 compound treatment 346535.0 -92700.0 -0.55 374660.0 -77400.0 -0.44 -0.7013 -0.9937 3010983 CMLD2_000388 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D15 mock treatment 234646.0 -205000.0 -1.22 394538.0 -57500.0 -0.33 -1.0923 -0.8663 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D16 mock treatment 418777.0 -20500.0 -0.12 477724.0 25700.0 0.15 0.0171 0.09 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D17 compound treatment 394995.0 -44300.0 -0.26 463326.0 11300.0 0.06 -0.1409 -0.5196 3130765 CMLD2_000389 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D18 compound treatment 430780.0 -8470.0 -0.05 435500.0 -16500.0 -0.09 -0.1022 -0.9573 3010984 CMLD2_000390 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D19 compound treatment 405292.0 -34000.0 -0.2 378561.0 -73500.0 -0.42 -0.4384 -0.9444 3130766 CMLD2_000391 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D20 compound treatment 426170.0 -13100.0 -0.08 443265.0 -8780.0 -0.05 -0.0903 -0.9769 3010985 CMLD2_000392 CO[C@@H]1/C=C/CC(=O)N[C@@H](C)C(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D21 compound treatment 443150.0 3900.0 0.02 463546.0 11500.0 0.07 0.0627 0.9028 3130767 CMLD2_000393 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D22 compound treatment 462274.0 23000.0 0.14 488141.0 36100.0 0.21 0.242 0.9807 3130768 CMLD2_000394 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D23 compound treatment 401210.0 -38000.0 -0.23 431645.0 -20400.0 -0.12 -0.2421 -0.9517 3130619 CMLD2_000395 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 D24 compound treatment 396102.0 -43100.0 -0.26 509463.0 57400.0 0.33 0.0493 0.1187 3010986 CMLD2_000396 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E01 mock treatment 421007.0 -18200.0 -0.11 463711.0 11700.0 0.07 -0.0299 -0.2346 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E02 mock treatment 448992.0 9740.0 0.06 249949.0 -202000.0 -1.15 -0.7716 -0.6706 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E03 compound treatment 452686.0 13400.0 0.08 492301.0 40300.0 0.23 0.2184 0.9007 3130769 CMLD2_000397 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E04 compound treatment 487154.0 47900.0 0.29 431472.0 -20600.0 -0.12 0.1189 0.3858 3130770 CMLD2_000398 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E05 compound treatment 518662.0 79400.0 0.47 556485.0 104000.0 0.59 0.7542 0.9936 3010987 CMLD2_000399 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E06 compound treatment 451916.0 12700.0 0.08 501597.0 49600.0 0.28 0.2526 0.8658 3130771 CMLD2_000400 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E07 compound treatment 475639.0 36400.0 0.22 398671.0 -53400.0 -0.3 -0.0615 -0.1649 3130772 CMLD2_000401 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E08 compound treatment 477898.0 38600.0 0.23 263051.0 -189000.0 -1.07 -0.5973 -0.5435 3010988 CMLD2_000402 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E09 mock treatment 433045.0 -6210.0 -0.04 467789.0 15700.0 0.09 0.0372 0.3841 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E10 mock treatment 452241.0 13000.0 0.08 215226.0 -237000.0 -1.35 -0.8976 -0.6654 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E11 compound treatment 460676.0 21400.0 0.13 467929.0 15900.0 0.09 0.154 0.9858 3130773 CMLD2_000403 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E12 compound treatment 427344.0 -11900.0 -0.07 179105.0 -273000.0 -1.55 -1.1476 -0.7386 3010989 CMLD2_000404 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E13 compound treatment 332656.0 -107000.0 -0.63 410669.0 -41400.0 -0.24 -0.6149 -0.9089 3130774 CMLD2_000405 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E14 compound treatment 452507.0 13300.0 0.08 441465.0 -10600.0 -0.06 0.0133 0.1336 3130775 CMLD2_000406 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E15 compound treatment 389031.0 -50200.0 -0.3 433046.0 -19000.0 -0.11 -0.2877 -0.9053 3010990 CMLD2_000407 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCC(C)C)n3c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E16 compound treatment 419156.0 -20100.0 -0.12 452633.0 593.0 0.0 -0.0822 -0.6869 3130776 CMLD2_000408 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E17 mock treatment 433380.0 -5870.0 -0.03 432278.0 -19800.0 -0.11 -0.1042 -0.8852 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E18 mock treatment 431108.0 -8140.0 -0.05 453494.0 1450.0 0.01 -0.0284 -0.5781 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E19 compound treatment 205026.0 -234000.0 -1.39 468148.0 16100.0 0.09 -0.9209 -0.6592 3010991 CMLD2_000409 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E20 compound treatment 481049.0 41800.0 0.25 464866.0 12800.0 0.07 0.2275 0.8775 3130777 CMLD2_000410 C[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E21 compound treatment 460257.0 21000.0 0.13 460527.0 8490.0 0.05 0.1225 0.9143 3130778 CMLD2_000411 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E22 compound treatment 453980.0 14700.0 0.09 408671.0 -43400.0 -0.25 -0.1124 -0.4295 3010992 CMLD2_000412 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E23 compound treatment 360380.0 -78900.0 -0.47 457444.0 5400.0 0.03 -0.3102 -0.6594 3130904 CMLD2_000413 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C)NS(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 E24 compound treatment 417459.0 -21800.0 -0.13 480660.0 28600.0 0.16 0.0234 0.1123 3130905 CMLD2_000414 CO[C@@H]1COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F01 mock treatment 534069.0 94800.0 0.56 471359.0 19300.0 0.11 0.4767 0.8292 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F02 mock treatment 501079.0 61800.0 0.37 284251.0 -168000.0 -0.95 -0.4145 -0.4053 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F03 compound treatment 191067.0 -248000.0 -1.48 528215.0 76200.0 0.43 -0.7381 -0.4795 3010993 CMLD2_000415 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F04 compound treatment 128271.0 -311000.0 -1.85 200498.0 -252000.0 -1.43 -2.3202 -0.9919 3130906 CMLD2_000416 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F05 compound treatment 559078.0 120000.0 0.71 316482.0 -136000.0 -0.77 -0.0408 -0.0389 3130907 CMLD2_000417 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F06 compound treatment 523202.0 84000.0 0.5 430430.0 -21600.0 -0.12 0.2664 0.5177 3011036 CMLD2_000418 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F07 compound treatment 464336.0 25100.0 0.15 488901.0 36900.0 0.21 0.2538 0.9862 3130908 CMLD2_000419 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F08 compound treatment 445339.0 6090.0 0.04 457719.0 5680.0 0.03 0.0485 0.9984 3130909 CMLD2_000420 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F09 mock treatment 587549.0 148000.0 0.88 239001.0 -213000.0 -1.21 -0.2326 -0.1552 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F10 mock treatment 490242.0 51000.0 0.3 452354.0 314.0 0.0 0.2158 0.7113 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F11 compound treatment 513895.0 74600.0 0.44 440540.0 -11500.0 -0.07 0.2679 0.5966 3011038 CMLD2_000421 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F12 compound treatment 457088.0 17800.0 0.11 230553.0 -221000.0 -1.26 -0.8156 -0.6452 3130910 CMLD2_000422 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F13 compound treatment 359604.0 -79600.0 -0.47 450936.0 -1100.0 -0.01 -0.3396 -0.7164 3011039 CMLD2_000423 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F14 compound treatment 442279.0 3030.0 0.02 449522.0 -2520.0 -0.01 0.0026 0.1135 3130911 CMLD2_000424 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F15 compound treatment 68058.0 -371000.0 -2.21 74434.0 -378000.0 -2.15 -3.0805 -0.9999 3130912 CMLD2_000425 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC\C=C(/C)\CCC=C(C)C)n3c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F16 compound treatment 435846.0 -3410.0 -0.02 466126.0 14100.0 0.08 0.0423 0.512 3011040 CMLD2_000426 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F17 mock treatment 418431.0 -20800.0 -0.12 416949.0 -35100.0 -0.2 -0.2287 -0.9737 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F18 mock treatment 182639.0 -257000.0 -1.53 506913.0 54900.0 0.31 -0.8592 -0.5512 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F19 compound treatment 510476.0 71200.0 0.42 458662.0 6620.0 0.04 0.3264 0.7669 3011041 CMLD2_000427 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F20 compound treatment 435968.0 -3280.0 -0.02 462464.0 10400.0 0.06 0.0281 0.4501 3130913 CMLD2_000428 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F21 compound treatment 418818.0 -20400.0 -0.12 477006.0 25000.0 0.14 0.0144 0.077 3130914 CMLD2_000429 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F22 compound treatment 137884.0 -301000.0 -1.79 413092.0 -38900.0 -0.22 -1.4249 -0.7884 3011043 CMLD2_000430 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC1=O)[C@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F23 compound treatment 445294.0 6040.0 0.04 495075.0 43000.0 0.24 0.1985 0.8024 3130915 CMLD2_000431 CO[C@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 F24 compound treatment 447207.0 7960.0 0.05 492380.0 40300.0 0.23 0.1957 0.8354 3011044 CMLD2_000432 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G01 compound treatment 442724.0 3470.0 0.02 561634.0 110000.0 0.62 0.4553 0.7301 3130916 CMLD2_000433 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G02 compound treatment 509625.0 70400.0 0.42 425184.0 -26900.0 -0.15 0.1882 0.4221 3130917 CMLD2_000434 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G03 mock treatment 494322.0 55100.0 0.33 468036.0 16000.0 0.09 0.2961 0.8705 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G04 mock treatment 447856.0 8600.0 0.05 126013.0 -326000.0 -1.85 -1.2748 -0.6873 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G05 compound treatment 461963.0 22700.0 0.14 519092.0 67100.0 0.38 0.3652 0.9027 3011046 CMLD2_000435 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G06 compound treatment 462399.0 23100.0 0.14 505749.0 53700.0 0.31 0.3134 0.9353 3130918 CMLD2_000436 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G07 compound treatment 454327.0 15100.0 0.09 493208.0 41200.0 0.23 0.229 0.9133 3130919 CMLD2_000437 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G08 compound treatment 479800.0 40500.0 0.24 502108.0 50100.0 0.28 0.372 0.9966 3011047 CMLD2_000438 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G09 compound treatment 414834.0 -24400.0 -0.15 388343.0 -63700.0 -0.36 -0.3589 -0.9195 3130920 CMLD2_000439 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G10 compound treatment 467741.0 28500.0 0.17 479939.0 27900.0 0.16 0.2321 0.9994 3011048 CMLD2_000440 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G11 compound treatment 468168.0 28900.0 0.17 428846.0 -23200.0 -0.13 0.0284 0.1311 3130921 CMLD2_000441 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G12 compound treatment 445287.0 6040.0 0.04 496842.0 44800.0 0.25 0.2056 0.7989 3131048 CMLD2_000442 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G13 compound treatment 154905.0 -284000.0 -1.69 155109.0 -297000.0 -1.69 -2.3906 -1.0 3011049 CMLD2_000443 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G14 compound treatment 443465.0 4210.0 0.03 457052.0 5010.0 0.03 0.0379 0.998 3131049 CMLD2_000444 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(CC)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G15 compound treatment 236842.0 -202000.0 -1.2 223551.0 -228000.0 -1.3 -1.7706 -0.9993 3011050 CMLD2_000445 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCCCC#C)n3c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G16 compound treatment 69997.0 -369000.0 -2.2 23350.0 -429000.0 -2.44 -3.2778 -0.9987 3131050 CMLD2_000446 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G17 compound treatment 459111.0 19900.0 0.12 435187.0 -16900.0 -0.1 0.0158 0.1039 3131051 CMLD2_000447 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G18 compound treatment 423276.0 -16000.0 -0.1 431907.0 -20100.0 -0.11 -0.1482 -0.9957 3011052 CMLD2_000448 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G19 mock treatment 387415.0 -51800.0 -0.31 460771.0 8730.0 0.05 -0.183 -0.5858 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G20 mock treatment 444514.0 5260.0 0.03 457241.0 5200.0 0.03 0.0431 0.9996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G21 compound treatment 414566.0 -24700.0 -0.15 442009.0 -10000.0 -0.06 -0.1442 -0.9151 3131052 CMLD2_000449 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C\C=C\[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G22 compound treatment 454331.0 15100.0 0.09 471949.0 19900.0 0.11 0.1435 0.9934 3011053 CMLD2_000450 C[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G23 compound treatment 453953.0 14700.0 0.09 516886.0 64800.0 0.37 0.3226 0.8512 3131053 CMLD2_000451 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@@H]3CCCN3C1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 G24 compound treatment 378596.0 -60700.0 -0.36 551283.0 99200.0 0.56 0.1438 0.2147 3131054 CMLD2_000452 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H01 compound treatment 609074.0 170000.0 1.01 517024.0 65000.0 0.37 0.976 0.9069 3011098 CMLD2_000453 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H02 compound treatment 513611.0 74400.0 0.44 493342.0 41300.0 0.23 0.479 0.9561 3131055 CMLD2_000454 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H03 mock treatment 522066.0 82800.0 0.49 216335.0 -236000.0 -1.34 -0.5993 -0.4196 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H04 mock treatment 221769.0 -217000.0 -1.29 472501.0 20500.0 0.12 -0.833 -0.641 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H05 compound treatment 470548.0 31300.0 0.19 485369.0 33300.0 0.19 0.2657 1.0 3131056 CMLD2_000455 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H06 compound treatment 447473.0 8220.0 0.05 441330.0 -10700.0 -0.06 -0.0085 -0.1084 3011099 CMLD2_000456 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H07 compound treatment 252601.0 -187000.0 -1.11 495572.0 43500.0 0.25 -0.6104 -0.5364 3131057 CMLD2_000457 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H08 compound treatment 495954.0 56700.0 0.34 500537.0 48500.0 0.28 0.4336 0.995 3011100 CMLD2_000458 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H09 compound treatment 490012.0 50800.0 0.3 440143.0 -11900.0 -0.07 0.1658 0.5355 3131058 CMLD2_000459 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H10 compound treatment 465859.0 26600.0 0.16 466548.0 14500.0 0.08 0.1703 0.9538 3131059 CMLD2_000460 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H11 compound treatment 492921.0 53700.0 0.32 537262.0 85200.0 0.48 0.5685 0.9795 3011101 CMLD2_000461 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H12 compound treatment 309295.0 -130000.0 -0.77 472962.0 20900.0 0.12 -0.4628 -0.5914 3131060 CMLD2_000462 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H13 compound treatment 482382.0 43100.0 0.26 452526.0 486.0 0.0 0.1835 0.7147 3131061 CMLD2_000463 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H14 compound treatment 444673.0 5420.0 0.03 458919.0 6880.0 0.04 0.0505 0.9954 3011102 CMLD2_000464 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H15 compound treatment 455917.0 16700.0 0.1 421350.0 -30700.0 -0.17 -0.0533 -0.2654 3131062 CMLD2_000465 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC[C@@H](O)COCc6ccco6)n3c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H16 compound treatment 292624.0 -147000.0 -0.87 484695.0 32700.0 0.19 -0.4857 -0.5444 3011103 CMLD2_000466 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H17 compound treatment 267148.0 -172000.0 -1.02 457899.0 5860.0 0.03 -0.7007 -0.6837 3131063 CMLD2_000467 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H18 compound treatment 466218.0 27000.0 0.16 458517.0 6480.0 0.04 0.1395 0.8474 3011104 CMLD2_000468 CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H19 mock treatment 429926.0 -9330.0 -0.06 431254.0 -20800.0 -0.12 -0.1228 -0.9406 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H20 mock treatment 434295.0 -4960.0 -0.03 487105.0 35100.0 0.2 0.1201 0.596 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H21 compound treatment 417924.0 -21300.0 -0.13 453267.0 1230.0 0.01 -0.0848 -0.6672 3131064 CMLD2_000469 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H22 compound treatment 405835.0 -33400.0 -0.2 532633.0 80600.0 0.46 0.1834 0.3672 3011105 CMLD2_000470 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H23 compound treatment 448972.0 9720.0 0.06 496876.0 44800.0 0.25 0.2212 0.846 3131065 CMLD2_000471 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 H24 compound treatment 393674.0 -45600.0 -0.27 498017.0 46000.0 0.26 -0.0069 -0.0184 3131066 CMLD2_000472 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I01 compound treatment 444563.0 5310.0 0.03 558531.0 106000.0 0.61 0.4506 0.743 3011106 CMLD2_000473 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I02 compound treatment 546716.0 107000.0 0.64 521666.0 69600.0 0.4 0.7322 0.9734 3131067 CMLD2_000474 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I03 compound treatment 493917.0 54700.0 0.33 557732.0 106000.0 0.6 0.655 0.9585 3131183 CMLD2_000475 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I04 compound treatment 500518.0 61300.0 0.36 508207.0 56200.0 0.32 0.4837 0.9978 3011108 CMLD2_000476 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I05 mock treatment 512620.0 73400.0 0.44 441315.0 -10700.0 -0.06 0.2656 0.6025 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I06 mock treatment 473661.0 34400.0 0.2 449650.0 -2390.0 -0.01 0.1352 0.6587 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I07 compound treatment 463483.0 24200.0 0.14 472000.0 20000.0 0.11 0.1822 0.993 3131184 CMLD2_000477 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I08 compound treatment 471600.0 32300.0 0.19 517383.0 65300.0 0.37 0.3989 0.9531 3011109 CMLD2_000478 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I09 compound treatment 458774.0 19500.0 0.12 492767.0 40700.0 0.23 0.2459 0.9491 3131185 CMLD2_000479 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I10 compound treatment 475891.0 36600.0 0.22 504801.0 52800.0 0.3 0.3663 0.9877 3131186 CMLD2_000480 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I11 compound treatment 460980.0 21700.0 0.13 445988.0 -6050.0 -0.03 0.0671 0.5014 3011110 CMLD2_000481 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I12 compound treatment 476799.0 37500.0 0.22 462194.0 10200.0 0.06 0.1988 0.8615 3131187 CMLD2_000482 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I13 compound treatment 444120.0 4870.0 0.03 452517.0 477.0 0.0 0.0224 0.7699 3131188 CMLD2_000483 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I14 compound treatment 387298.0 -52000.0 -0.31 498717.0 46700.0 0.27 -0.0309 -0.0759 3011112 CMLD2_000484 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I15 compound treatment 437901.0 -1350.0 -0.01 474496.0 22500.0 0.13 0.0846 0.6613 3131189 CMLD2_000485 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCc5ccccc5)n2c1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I16 compound treatment 69162.0 -370000.0 -2.2 71486.0 -381000.0 -2.16 -3.0877 -1.0 3011154 CMLD2_000486 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I17 compound treatment 472901.0 33600.0 0.2 480944.0 28900.0 0.16 0.2578 0.9952 3131190 CMLD2_000487 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I18 compound treatment 453736.0 14500.0 0.09 428007.0 -24000.0 -0.14 -0.0357 -0.2209 3010995 CMLD2_000488 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I19 compound treatment 214897.0 -224000.0 -1.34 219081.0 -233000.0 -1.32 -1.8809 -1.0 3131191 CMLD2_000489 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I20 compound treatment 446541.0 7290.0 0.04 455314.0 3270.0 0.02 0.0438 0.9287 3131192 CMLD2_000490 C[C@H]/1COC(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I21 mock treatment 415077.0 -24200.0 -0.14 429185.0 -22900.0 -0.13 -0.1936 -0.9987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I22 mock treatment 416425.0 -22800.0 -0.14 462131.0 10100.0 0.06 -0.0555 -0.3762 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I23 compound treatment 493258.0 54000.0 0.32 466806.0 14800.0 0.08 0.2866 0.8629 3131193 CMLD2_000491 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 I24 compound treatment 424624.0 -14600.0 -0.09 454522.0 2480.0 0.01 -0.0516 -0.5848 3011157 CMLD2_000492 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J01 compound treatment 539864.0 101000.0 0.6 565793.0 114000.0 0.65 0.8808 0.9993 3131194 CMLD2_000493 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J02 compound treatment 505310.0 66100.0 0.39 261648.0 -190000.0 -1.08 -0.4876 -0.4233 3011158 CMLD2_000494 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J03 compound treatment 488468.0 49200.0 0.29 526346.0 74300.0 0.42 0.5059 0.984 3131195 CMLD2_000495 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J04 compound treatment 283737.0 -156000.0 -0.93 455185.0 3140.0 0.02 -0.6418 -0.6933 3011159 CMLD2_000496 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J05 mock treatment 360697.0 -78600.0 -0.47 496744.0 44700.0 0.25 -0.1508 -0.2834 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J06 mock treatment 440098.0 846.0 0.01 584443.0 132000.0 0.75 0.536 0.7118 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J07 compound treatment 496028.0 56800.0 0.34 511033.0 59000.0 0.34 0.4761 1.0 3131196 CMLD2_000497 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J08 compound treatment 455188.0 15900.0 0.09 487673.0 35600.0 0.2 0.2103 0.9402 3131197 CMLD2_000498 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J09 compound treatment 485374.0 46100.0 0.27 499999.0 48000.0 0.27 0.3869 1.0 3011160 CMLD2_000499 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J10 compound treatment 429061.0 -10200.0 -0.06 252190.0 -200000.0 -1.14 -0.8465 -0.7438 3131198 CMLD2_000500 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J11 compound treatment 291171.0 -148000.0 -0.88 423220.0 -28800.0 -0.16 -0.7391 -0.8245 3011161 CMLD2_000501 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J12 compound treatment 585315.0 146000.0 0.87 499329.0 47300.0 0.27 0.8048 0.8845 3131199 CMLD2_000502 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J13 compound treatment 460743.0 21500.0 0.13 439898.0 -12100.0 -0.07 0.0416 0.2863 3131200 CMLD2_000503 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J14 compound treatment 231943.0 -207000.0 -1.23 434256.0 -17800.0 -0.1 -0.9439 -0.7625 3011162 CMLD2_000504 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J15 compound treatment 454083.0 14800.0 0.09 483988.0 31900.0 0.18 0.1909 0.945 3131201 CMLD2_000505 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J16 compound treatment 481036.0 41800.0 0.25 495680.0 43600.0 0.25 0.3513 1.0 3011163 CMLD2_000506 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J17 compound treatment 449885.0 10600.0 0.06 459244.0 7200.0 0.04 0.0737 0.9778 3131202 CMLD2_000507 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J18 compound treatment 265138.0 -174000.0 -1.04 464902.0 12900.0 0.07 -0.681 -0.6556 3011164 CMLD2_000508 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J19 compound treatment 324413.0 -115000.0 -0.68 464347.0 12300.0 0.07 -0.4338 -0.6314 3131320 CMLD2_000509 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J20 compound treatment 419800.0 -19500.0 -0.12 493470.0 41400.0 0.24 0.0847 0.3228 3131321 CMLD2_000510 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J21 mock treatment 322054.0 -117000.0 -0.7 468482.0 16400.0 0.09 -0.4271 -0.6069 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J22 mock treatment 201998.0 -237000.0 -1.41 452860.0 820.0 0.0 -0.9951 -0.7048 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J23 compound treatment 138515.0 -301000.0 -1.79 510788.0 58700.0 0.33 -1.0294 -0.5654 1952481 CMLD2_000511 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 J24 compound treatment 449230.0 9980.0 0.06 517414.0 65400.0 0.37 0.3049 0.8098 3131322 CMLD2_000512 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K01 compound treatment 537437.0 98200.0 0.58 526703.0 74700.0 0.42 0.7134 0.9877 3131323 CMLD2_000513 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K02 compound treatment 514647.0 75400.0 0.45 553898.0 102000.0 0.58 0.7269 0.992 3011055 CMLD2_000514 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K03 compound treatment 333910.0 -105000.0 -0.63 402918.0 -49100.0 -0.28 -0.6408 -0.9337 3131324 CMLD2_000515 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K04 compound treatment 505124.0 65900.0 0.39 496813.0 44800.0 0.25 0.4572 0.9782 3011057 CMLD2_000516 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K05 compound treatment 570704.0 131000.0 0.78 520456.0 68400.0 0.39 0.8283 0.948 3131325 CMLD2_000517 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K06 compound treatment 482675.0 43400.0 0.26 564186.0 112000.0 0.64 0.6337 0.9209 3131326 CMLD2_000518 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K07 mock treatment 524919.0 85700.0 0.51 521170.0 69100.0 0.39 0.6385 0.9917 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K08 mock treatment 492336.0 53100.0 0.32 459011.0 6970.0 0.04 0.2514 0.7896 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K09 compound treatment 538322.0 99100.0 0.59 474031.0 22000.0 0.13 0.5053 0.8384 3011058 CMLD2_000519 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K10 compound treatment 517203.0 78000.0 0.46 548700.0 96700.0 0.55 0.7167 0.9964 3131327 CMLD2_000520 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K11 compound treatment 350633.0 -88600.0 -0.53 390996.0 -61000.0 -0.35 -0.6184 -0.9794 3011059 CMLD2_000521 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K12 compound treatment 491155.0 51900.0 0.31 519364.0 67300.0 0.38 0.4891 0.9943 3131328 CMLD2_000522 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K13 compound treatment 515740.0 76500.0 0.46 476311.0 24300.0 0.14 0.4195 0.8819 3131329 CMLD2_000523 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K14 compound treatment 420185.0 -19100.0 -0.11 414327.0 -37700.0 -0.21 -0.2319 -0.9557 3011060 CMLD2_000524 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(c6ccccc6)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K15 mock treatment 471992.0 32700.0 0.19 486174.0 34100.0 0.19 0.275 1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K16 mock treatment 455508.0 16300.0 0.1 475681.0 23600.0 0.13 0.1635 0.987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K17 compound treatment 488770.0 49500.0 0.29 477019.0 25000.0 0.14 0.3088 0.944 3131330 CMLD2_000525 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K18 compound treatment 161443.0 -278000.0 -1.65 415639.0 -36400.0 -0.21 -1.3155 -0.7895 3011061 CMLD2_000526 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K19 compound treatment 480577.0 41300.0 0.25 487429.0 35400.0 0.2 0.3162 0.995 3131331 CMLD2_000527 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K20 compound treatment 156410.0 -283000.0 -1.68 468259.0 16200.0 0.09 -1.1251 -0.6674 3011062 CMLD2_000528 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K21 compound treatment 421204.0 -18000.0 -0.11 463873.0 11800.0 0.07 -0.0284 -0.2238 3011070 CMLD2_000529 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K22 compound treatment 407150.0 -32100.0 -0.19 552486.0 100000.0 0.57 0.2688 0.4463 3011072 CMLD2_000530 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)COC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K23 mock treatment 508764.0 69500.0 0.41 512301.0 60300.0 0.34 0.5348 0.9956 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 K24 mock treatment 469778.0 30500.0 0.18 507377.0 55300.0 0.31 0.351 0.9659 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L01 compound treatment 517323.0 78100.0 0.46 562372.0 110000.0 0.63 0.7722 0.9891 3131332 CMLD2_000531 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L02 compound treatment 532130.0 92900.0 0.55 503703.0 51700.0 0.29 0.5986 0.9563 3131333 CMLD2_000532 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L03 compound treatment 529546.0 90300.0 0.54 595611.0 144000.0 0.82 0.9573 0.9794 3011074 CMLD2_000533 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L04 compound treatment 492808.0 53600.0 0.32 473330.0 21300.0 0.12 0.311 0.9121 3131334 CMLD2_000534 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L05 compound treatment 397586.0 -41700.0 -0.25 299691.0 -152000.0 -0.87 -0.788 -0.8744 3131335 CMLD2_000535 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L06 compound treatment 460658.0 21400.0 0.13 513756.0 61700.0 0.35 0.3383 0.9059 3011078 CMLD2_000536 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L07 mock treatment 483706.0 44500.0 0.26 508202.0 56200.0 0.32 0.4129 0.9956 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L08 mock treatment 421432.0 -17800.0 -0.11 520915.0 68900.0 0.39 0.202 0.4977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L09 compound treatment 487612.0 48400.0 0.29 502312.0 50300.0 0.29 0.4057 1.0 3011128 CMLD2_000537 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L10 compound treatment 504398.0 65100.0 0.39 497420.0 45400.0 0.26 0.4566 0.9804 3131336 CMLD2_000538 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L11 compound treatment 522917.0 83700.0 0.5 555547.0 104000.0 0.59 0.7683 0.9965 3011131 CMLD2_000539 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L12 compound treatment 444662.0 5410.0 0.03 479512.0 27500.0 0.16 0.1332 0.8353 3131337 CMLD2_000540 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L13 compound treatment 490414.0 51200.0 0.3 521529.0 69500.0 0.4 0.4947 0.9917 3131338 CMLD2_000541 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L14 compound treatment 518897.0 79600.0 0.47 482182.0 30100.0 0.17 0.4564 0.9054 3011134 CMLD2_000542 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L15 mock treatment 468845.0 29600.0 0.18 454076.0 2040.0 0.01 0.1327 0.752 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L16 mock treatment 458556.0 19300.0 0.11 499691.0 47700.0 0.27 0.2728 0.927 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L17 compound treatment 486277.0 47000.0 0.28 487063.0 35000.0 0.2 0.3387 0.9861 3131454 CMLD2_000543 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L18 compound treatment 66854.0 -372000.0 -2.22 78189.0 -374000.0 -2.13 -3.0705 -0.9998 3011136 CMLD2_000544 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]4[C@H]([C@H](O)[C@@H]5O[C@@H]5C4=O)n3c2=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L19 compound treatment 497974.0 58700.0 0.35 512695.0 60700.0 0.34 0.491 1.0 3131455 CMLD2_000545 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L20 compound treatment 178837.0 -260000.0 -1.55 479119.0 27100.0 0.15 -0.987 -0.6337 3131456 CMLD2_000546 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2)NS(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L21 compound treatment 474572.0 35300.0 0.21 458314.0 6270.0 0.04 0.1739 0.8155 3011138 CMLD2_000547 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L22 compound treatment 504745.0 65500.0 0.39 521421.0 69400.0 0.39 0.5546 1.0 3131457 CMLD2_000548 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L23 mock treatment 461785.0 22500.0 0.13 464132.0 12100.0 0.07 0.1434 0.9518 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 L24 mock treatment 514265.0 75000.0 0.45 487624.0 35600.0 0.2 0.4588 0.936 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M01 compound treatment 488996.0 49700.0 0.3 548367.0 96300.0 0.55 0.5967 0.9583 3011140 CMLD2_000549 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M02 compound treatment 513550.0 74300.0 0.44 488073.0 36000.0 0.2 0.4576 0.9389 3131458 CMLD2_000550 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M03 compound treatment 150417.0 -289000.0 -1.72 263651.0 -188000.0 -1.07 -1.973 -0.9741 3131459 CMLD2_000551 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M04 compound treatment 311305.0 -128000.0 -0.76 538625.0 86600.0 0.49 -0.1903 -0.2098 3011143 CMLD2_000552 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M05 compound treatment 580746.0 141000.0 0.84 560688.0 109000.0 0.62 1.0323 0.9884 3011168 CMLD2_000553 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M06 compound treatment 511736.0 72500.0 0.43 550312.0 98300.0 0.56 0.7002 0.9918 3131460 CMLD2_000554 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M07 compound treatment 490943.0 51700.0 0.31 528227.0 76200.0 0.43 0.5239 0.9859 3011171 CMLD2_000555 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M08 compound treatment 454266.0 15000.0 0.09 456392.0 4350.0 0.02 0.0807 0.8702 3131461 CMLD2_000556 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M09 mock treatment 493722.0 54500.0 0.32 540119.0 88100.0 0.5 0.5834 0.9778 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M10 mock treatment 491992.0 52700.0 0.31 551797.0 99800.0 0.57 0.6231 0.961 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M11 compound treatment 100277.0 -339000.0 -2.02 84850.0 -367000.0 -2.09 -2.903 -0.9999 3011173 CMLD2_000557 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M12 compound treatment 488883.0 49600.0 0.3 515435.0 63400.0 0.36 0.4638 0.9951 3131462 CMLD2_000558 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(CC)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M13 mock treatment 536462.0 97200.0 0.58 487028.0 35000.0 0.2 0.5498 0.8986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M14 mock treatment 498695.0 59400.0 0.35 532883.0 80800.0 0.46 0.5752 0.9916 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M15 compound treatment 449375.0 10100.0 0.06 469808.0 17800.0 0.1 0.114 0.9695 3131463 CMLD2_000559 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M16 compound treatment 67880.0 -371000.0 -2.21 68233.0 -384000.0 -2.18 -3.1062 -1.0 3011176 CMLD2_000560 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M17 compound treatment 434886.0 -4370.0 -0.03 490497.0 38500.0 0.22 0.1363 0.6187 3131464 CMLD2_000561 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M18 compound treatment 275916.0 -163000.0 -0.97 527985.0 75900.0 0.43 -0.382 -0.3591 3011178 CMLD2_000562 Cn1c(=O)n2CC[C@H]3[C@H]([C@H](O)[C@@H]4O[C@@H]4C3=O)n2c1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M19 compound treatment 479413.0 40200.0 0.24 508794.0 56800.0 0.32 0.3972 0.9891 3131465 CMLD2_000563 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M20 compound treatment 482766.0 43500.0 0.26 485361.0 33300.0 0.19 0.3171 0.9882 3011181 CMLD2_000564 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M21 compound treatment 483993.0 44700.0 0.27 457074.0 5030.0 0.03 0.2085 0.7786 3131466 CMLD2_000565 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M22 compound treatment 468252.0 29000.0 0.17 471070.0 19000.0 0.11 0.1986 0.9747 3011183 CMLD2_000566 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M23 compound treatment 482776.0 43500.0 0.26 510708.0 58700.0 0.33 0.4191 0.9922 3131467 CMLD2_000567 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 M24 compound treatment 490825.0 51600.0 0.31 451332.0 -708.0 0.0 0.2142 0.6978 3131468 CMLD2_000568 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N01 compound treatment 69040.0 -370000.0 -2.2 79562.0 -372000.0 -2.12 -3.0557 -0.9998 3131469 CMLD2_000569 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N02 compound treatment 473977.0 34700.0 0.21 508315.0 56300.0 0.32 0.3724 0.9776 3011201 CMLD2_000570 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N03 compound treatment 509920.0 70700.0 0.42 535296.0 83300.0 0.47 0.6322 0.9983 3131470 CMLD2_000571 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N04 compound treatment 450572.0 11300.0 0.07 483081.0 31000.0 0.18 0.1725 0.9128 3131471 CMLD2_000572 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N05 compound treatment 513540.0 74300.0 0.44 492863.0 40800.0 0.23 0.4768 0.9548 3011203 CMLD2_000573 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N06 compound treatment 515837.0 76600.0 0.46 497056.0 45000.0 0.26 0.5033 0.9628 3131472 CMLD2_000574 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N07 compound treatment 464436.0 25200.0 0.15 464715.0 12700.0 0.07 0.1569 0.9437 3011205 CMLD2_000575 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N08 compound treatment 491765.0 52500.0 0.31 477769.0 25700.0 0.15 0.3244 0.9402 3131588 CMLD2_000576 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N09 mock treatment 517664.0 78400.0 0.47 494516.0 42500.0 0.24 0.5008 0.953 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N10 mock treatment 502783.0 63500.0 0.38 535953.0 83900.0 0.48 0.6048 0.9934 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N11 compound treatment 477107.0 37900.0 0.23 529450.0 77400.0 0.44 0.4706 0.9516 3011207 CMLD2_000577 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N12 compound treatment 505514.0 66300.0 0.39 491220.0 39200.0 0.22 0.4364 0.9635 3131589 CMLD2_000578 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N13 mock treatment 281461.0 -158000.0 -0.94 473080.0 21000.0 0.12 -0.5794 -0.6121 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N14 mock treatment 500774.0 61500.0 0.37 491384.0 39300.0 0.22 0.4171 0.9721 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N15 compound treatment 187308.0 -252000.0 -1.5 504371.0 52300.0 0.3 -0.8498 -0.5559 3131590 CMLD2_000579 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCCCC#C)n2c1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N16 compound treatment 65801.0 -373000.0 -2.22 70251.0 -382000.0 -2.17 -3.1068 -0.9999 3011210 CMLD2_000580 C[C@@H](N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N17 compound treatment 470210.0 31000.0 0.18 508789.0 56700.0 0.32 0.3585 0.9647 3131591 CMLD2_000581 C[C@H](N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N18 compound treatment 149182.0 -290000.0 -1.73 328409.0 -124000.0 -0.7 -1.7178 -0.9216 3011211 CMLD2_000582 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N19 compound treatment 472360.0 33100.0 0.2 464850.0 12800.0 0.07 0.1908 0.9084 3131592 CMLD2_000583 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N20 compound treatment 481457.0 42200.0 0.25 522728.0 70700.0 0.4 0.4619 0.9744 3131593 CMLD2_000584 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N21 compound treatment 473010.0 33800.0 0.2 512039.0 60000.0 0.34 0.3833 0.9681 3011214 CMLD2_000585 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@H](C)C(=O)OC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N22 compound treatment 507822.0 68600.0 0.41 502805.0 50800.0 0.29 0.4927 0.9856 3011226 CMLD2_000586 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N23 compound treatment 448039.0 8790.0 0.05 513202.0 61200.0 0.35 0.2829 0.8044 3131594 CMLD2_000587 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]3CCCN3C(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 N24 compound treatment 510823.0 71600.0 0.43 459017.0 6980.0 0.04 0.3292 0.7696 3131054 CMLD2_000588 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O01 compound treatment 493970.0 54700.0 0.33 475418.0 23400.0 0.13 0.3243 0.9219 3131595 CMLD2_000589 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O02 compound treatment 435647.0 -3600.0 -0.02 412020.0 -40000.0 -0.23 -0.1761 -0.7704 3011229 CMLD2_000590 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O03 compound treatment 505079.0 65800.0 0.39 510327.0 58300.0 0.33 0.5114 0.9965 3131596 CMLD2_000591 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O04 compound treatment 476707.0 37500.0 0.22 465767.0 13700.0 0.08 0.2128 0.9011 3011196 CMLD2_000592 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O05 compound treatment 506458.0 67200.0 0.4 508867.0 56800.0 0.32 0.5113 0.9944 3131597 CMLD2_000593 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O06 compound treatment 538573.0 99300.0 0.59 557883.0 106000.0 0.6 0.8436 1.0 3131598 CMLD2_000594 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O07 compound treatment 210571.0 -229000.0 -1.36 528030.0 76000.0 0.43 -0.6568 -0.46 3011231 CMLD2_000595 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O08 compound treatment 462957.0 23700.0 0.14 512986.0 60900.0 0.35 0.3448 0.9215 3131599 CMLD2_000596 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O09 compound treatment 476419.0 37200.0 0.22 529675.0 77600.0 0.44 0.4686 0.9489 3011237 CMLD2_000597 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O10 compound treatment 380788.0 -58500.0 -0.35 446458.0 -5580.0 -0.03 -0.2685 -0.7684 3131600 CMLD2_000598 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O11 mock treatment 527296.0 88000.0 0.52 518306.0 66300.0 0.38 0.637 0.9869 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O12 mock treatment 507550.0 68300.0 0.41 462098.0 10100.0 0.06 0.3279 0.7987 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O13 compound treatment 515662.0 76400.0 0.45 508110.0 56100.0 0.32 0.547 0.9849 3011239 CMLD2_000599 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O14 compound treatment 86301.0 -353000.0 -2.1 101685.0 -350000.0 -1.99 -2.8941 -0.9997 3131601 CMLD2_000600 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)/C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O15 compound treatment 495806.0 56600.0 0.34 464197.0 12200.0 0.07 0.2869 0.8349 3131602 CMLD2_000601 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OC[C@@H](O)COCc5ccco5)n2c1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O16 compound treatment 53366.0 -386000.0 -2.3 63707.0 -388000.0 -2.21 -3.1855 -0.9998 3012175 CMLD2_000602 CCOC(=O)CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O17 compound treatment 462818.0 23600.0 0.14 454086.0 2050.0 0.01 0.1074 0.7631 3012176 CMLD2_000603 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O18 compound treatment 421813.0 -17400.0 -0.1 437021.0 -15000.0 -0.09 -0.1338 -0.9953 3012177 CMLD2_000604 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccccc4)C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O19 compound treatment 511098.0 71800.0 0.43 482605.0 30600.0 0.17 0.4253 0.9213 3012178 CMLD2_000605 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O20 compound treatment 469379.0 30100.0 0.18 495375.0 43300.0 0.25 0.301 0.9878 3012179 CMLD2_000606 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O21 compound treatment 476313.0 37100.0 0.22 447543.0 -4500.0 -0.03 0.1379 0.621 3131603 CMLD2_000607 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@@H](C)C(=O)OC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O22 compound treatment 451949.0 12700.0 0.08 450072.0 -1970.0 -0.01 0.0455 0.5959 3011105 CMLD2_000608 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O23 compound treatment 457051.0 17800.0 0.11 494122.0 42100.0 0.24 0.2441 0.9328 3012180 CMLD2_000609 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 O24 compound treatment 501887.0 62600.0 0.37 480118.0 28100.0 0.16 0.3765 0.9284 3131604 CMLD2_000610 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P01 compound treatment 551161.0 112000.0 0.67 489366.0 37300.0 0.21 0.621 0.8884 3131605 CMLD2_000611 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P02 compound treatment 534751.0 95500.0 0.57 509951.0 57900.0 0.33 0.6348 0.9663 3012181 CMLD2_000612 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P03 compound treatment 429609.0 -9640.0 -0.06 479225.0 27200.0 0.15 0.0687 0.4168 3131606 CMLD2_000613 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P04 compound treatment 237564.0 -202000.0 -1.2 469333.0 17300.0 0.1 -0.7792 -0.647 3012182 CMLD2_000614 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P05 compound treatment 220096.0 -219000.0 -1.3 519334.0 67300.0 0.38 -0.6517 -0.4794 3131723 CMLD2_000615 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P06 compound treatment 81691.0 -358000.0 -2.13 109025.0 -343000.0 -1.95 -2.884 -0.9991 3131724 CMLD2_000616 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P07 compound treatment 204684.0 -235000.0 -1.4 512335.0 60300.0 0.34 -0.7447 -0.518 3012183 CMLD2_000617 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P08 compound treatment 327230.0 -112000.0 -0.67 544583.0 92500.0 0.53 -0.0993 -0.1169 3131725 CMLD2_000618 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P09 compound treatment 486108.0 46900.0 0.28 364304.0 -87700.0 -0.5 -0.1556 -0.2723 3012184 CMLD2_000619 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P10 compound treatment 424662.0 -14600.0 -0.09 464932.0 12900.0 0.07 -0.0096 -0.0841 3131726 CMLD2_000620 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P11 mock treatment 476805.0 37600.0 0.22 526290.0 74200.0 0.42 0.4566 0.9558 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P12 mock treatment 318039.0 -121000.0 -0.72 462182.0 10100.0 0.06 -0.4693 -0.6485 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P13 compound treatment 502250.0 63000.0 0.37 526577.0 74500.0 0.42 0.5648 0.9981 3131727 CMLD2_000621 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P14 compound treatment 444415.0 5160.0 0.03 449808.0 -2230.0 -0.01 0.0128 0.3835 3012185 CMLD2_000622 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P15 compound treatment 388080.0 -51200.0 -0.3 346451.0 -106000.0 -0.6 -0.6399 -0.9505 3131728 CMLD2_000623 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P16 compound treatment 48671.0 -391000.0 -2.32 67180.0 -385000.0 -2.19 -3.1913 -0.9995 3012186 CMLD2_000624 CC(C)(C)N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P17 compound treatment 441025.0 1770.0 0.01 521905.0 69900.0 0.4 0.2884 0.7256 3131729 CMLD2_000625 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P18 compound treatment 444681.0 5430.0 0.03 485387.0 33300.0 0.19 0.1569 0.8158 3012187 CMLD2_000626 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P19 compound treatment 470904.0 31700.0 0.19 505723.0 53700.0 0.31 0.3491 0.9731 3131730 CMLD2_000627 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P20 compound treatment 464006.0 24800.0 0.15 513092.0 61100.0 0.35 0.3497 0.9271 3012188 CMLD2_000628 C[C@H]/1COC(=O)C\C=C\[C@@H](C)[C@H]2O[C@H](COC(=O)C\C=C1)[C@@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P21 compound treatment 489459.0 50200.0 0.3 472235.0 20200.0 0.11 0.2925 0.9137 3131731 CMLD2_000629 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P22 compound treatment 472378.0 33100.0 0.2 525248.0 73200.0 0.42 0.4338 0.9417 3012189 CMLD2_000630 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)COC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P23 compound treatment 498889.0 59600.0 0.35 464605.0 12600.0 0.07 0.3015 0.8328 3131732 CMLD2_000631 CO[C@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](OCc3ccccc3)/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2110 P24 compound treatment 497549.0 58300.0 0.35 476559.0 24500.0 0.14 0.3439 0.9198 3131733 CMLD2_000632 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A01 compound treatment 347076.0 -95300.0 -0.57 383740.0 -34300.0 -0.19 -0.5388 -0.8985 3012190 CMLD2_000633 CO[C@@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A02 compound treatment 105929.0 -336000.0 -2.0 460435.0 42400.0 0.24 -1.2453 -0.6175 3131321 CMLD2_000634 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A03 compound treatment 391465.0 -50900.0 -0.3 491661.0 73600.0 0.42 0.0819 0.1585 3131734 CMLD2_000635 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A04 compound treatment 323239.0 -119000.0 -0.71 315614.0 -102000.0 -0.58 -0.9131 -0.9952 3131735 CMLD2_000636 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A05 compound treatment 353122.0 -89200.0 -0.53 356774.0 -61200.0 -0.35 -0.6218 -0.9791 3012191 CMLD2_000637 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A06 compound treatment 485802.0 43400.0 0.26 508932.0 90900.0 0.52 0.5484 0.9487 3131736 CMLD2_000638 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A07 compound treatment 434979.0 -7390.0 -0.04 481549.0 63500.0 0.36 0.2244 0.6165 3012192 CMLD2_000639 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A08 compound treatment 140465.0 -302000.0 -1.8 472349.0 54300.0 0.31 -1.052 -0.577 3131737 CMLD2_000640 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A09 compound treatment 160475.0 -282000.0 -1.68 509165.0 91100.0 0.52 -0.8198 -0.4669 3131738 CMLD2_000641 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)cc2)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A10 compound treatment 443118.0 751.0 0.0 475953.0 57900.0 0.33 0.2361 0.7166 3012193 CMLD2_000642 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A11 compound treatment 157435.0 -285000.0 -1.7 537842.0 120000.0 0.68 -0.7172 -0.3925 3131739 CMLD2_000643 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A12 compound treatment 55433.0 -387000.0 -2.3 464179.0 46200.0 0.26 -1.4427 -0.6225 3012194 CMLD2_000644 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A13 mock treatment 519691.0 77300.0 0.46 478187.0 60200.0 0.34 0.5674 0.9894 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A14 mock treatment 455842.0 13500.0 0.08 495756.0 77700.0 0.44 0.3693 0.822 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A15 compound treatment 160745.0 -282000.0 -1.68 207573.0 -210000.0 -1.2 -2.0314 -0.9864 3131740 CMLD2_000645 CCc1cc2CN(CC/C(=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A16 compound treatment 47370.0 -395000.0 -2.35 189929.0 -228000.0 -1.3 -2.5794 -0.9607 3131741 CMLD2_000646 CCc1cc2CN(CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A17 compound treatment 408234.0 -34100.0 -0.2 330767.0 -87200.0 -0.5 -0.4945 -0.9223 3012195 CMLD2_000647 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cc(no5)c6c(C)cc(C)cc6C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A18 compound treatment 442949.0 582.0 0.0 433195.0 15200.0 0.09 0.0635 0.7349 3131860 CMLD2_000648 CO[C@H](/C=N/O[C@@H](C)c1cc(no1)c2c(C)cc(C)cc2C)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A19 compound treatment 556592.0 114000.0 0.68 221600.0 -196000.0 -1.12 -0.3091 -0.2364 3012196 CMLD2_000649 C[C@H](ON=C(C)C)c1cc(no1)c2c(C)cc(C)cc2C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A20 compound treatment 570687.0 128000.0 0.76 176677.0 -241000.0 -1.37 -0.4304 -0.2741 3131861 CMLD2_000650 CO/N=C/[C@@H](C)[C@H](OCc1ccccc1)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A21 compound treatment 396389.0 -46000.0 -0.27 179193.0 -239000.0 -1.36 -1.1538 -0.8328 3131714 CMLD2_000651 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A22 compound treatment 121669.0 -321000.0 -1.91 496003.0 78000.0 0.44 -1.036 -0.5287 3012197 CMLD2_000652 C[C@@H]1CC[C@@H]2N(C[C@@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A23 mock treatment 517872.0 75500.0 0.45 494770.0 76800.0 0.44 0.6264 0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 A24 mock treatment 522476.0 80100.0 0.48 459402.0 41400.0 0.24 0.5035 0.9471 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B01 compound treatment 532263.0 89900.0 0.54 506737.0 88700.0 0.5 0.7351 0.9996 3131862 CMLD2_000653 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B02 compound treatment 546729.0 104000.0 0.62 571043.0 153000.0 0.87 1.0545 0.9863 3011062 CMLD2_000654 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B03 compound treatment 458665.0 16300.0 0.1 489207.0 71200.0 0.4 0.3549 0.8524 3131863 CMLD2_000655 CO[C@@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B04 compound treatment 334999.0 -107000.0 -0.64 340314.0 -77700.0 -0.44 -0.7643 -0.9838 3012198 CMLD2_000656 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B05 compound treatment 455293.0 12900.0 0.08 381078.0 -36900.0 -0.21 -0.0941 -0.4208 3131864 CMLD2_000657 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cc(no4)c5c(C)cc(C)cc5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B06 compound treatment 431274.0 -11100.0 -0.07 496120.0 78100.0 0.44 0.2674 0.5955 3131865 CMLD2_000658 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cc(no2)c3c(C)cc(C)cc3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B07 compound treatment 483925.0 41600.0 0.25 525358.0 107000.0 0.61 0.6065 0.9209 3012199 CMLD2_000659 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B08 compound treatment 393140.0 -49200.0 -0.29 446742.0 28700.0 0.16 -0.0916 -0.2732 3131866 CMLD2_000660 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B09 compound treatment 430435.0 -11900.0 -0.07 431741.0 13700.0 0.08 0.005 0.0472 3131867 CMLD2_000661 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B10 compound treatment 336405.0 -106000.0 -0.63 348447.0 -69600.0 -0.4 -0.7257 -0.9748 3012228 CMLD2_000662 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B11 compound treatment 563918.0 122000.0 0.72 474448.0 56400.0 0.32 0.7384 0.9331 3131868 CMLD2_000663 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B12 compound treatment 473633.0 31300.0 0.19 441859.0 23800.0 0.14 0.2275 0.9879 3130911 CMLD2_000664 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B13 mock treatment 482849.0 40500.0 0.24 506855.0 88800.0 0.51 0.5276 0.9426 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B14 mock treatment 420902.0 -21500.0 -0.13 472689.0 54700.0 0.31 0.1295 0.3853 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B15 compound treatment 67303.0 -375000.0 -2.23 77206.0 -341000.0 -1.94 -2.9488 -0.9975 3131869 CMLD2_000665 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(CC)c(CC)cc3C2)C=C[C@@H]1Oc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B16 compound treatment 443215.0 848.0 0.01 501857.0 83800.0 0.48 0.3407 0.7146 3012230 CMLD2_000666 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B17 compound treatment 380733.0 -61600.0 -0.37 323969.0 -94000.0 -0.53 -0.6375 -0.9831 3131870 CMLD2_000667 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B18 compound treatment 373871.0 -68500.0 -0.41 445025.0 27000.0 0.15 -0.1796 -0.4124 3012231 CMLD2_000668 CO[C@H](/C=N/OC[C@@H](C)[C@H](OCc1ccccc1)C(C)C)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B19 compound treatment 350555.0 -91800.0 -0.55 436338.0 18300.0 0.1 -0.3127 -0.5621 3131871 CMLD2_000669 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CON=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B20 compound treatment 534724.0 92400.0 0.55 492974.0 75000.0 0.43 0.6901 0.9921 3012232 CMLD2_000670 CCc1cc2CN(CC/C(=N/OC)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B21 compound treatment 61561.0 -381000.0 -2.27 60262.0 -358000.0 -2.03 -3.0411 -0.9985 3131872 CMLD2_000671 C[C@@H]1CC[C@@H]2N(C[C@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B22 compound treatment 548696.0 106000.0 0.63 512902.0 94900.0 0.54 0.829 0.9969 3131873 CMLD2_000672 COc1ccc(OC[C@H]2CN3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B23 mock treatment 503205.0 60800.0 0.36 473505.0 55500.0 0.32 0.4792 0.9977 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 B24 mock treatment 552647.0 110000.0 0.66 443303.0 25300.0 0.14 0.5658 0.8421 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C01 compound treatment 336724.0 -106000.0 -0.63 472035.0 54000.0 0.31 -0.2274 -0.3249 3012233 CMLD2_000673 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C02 compound treatment 487322.0 45000.0 0.27 442170.0 24200.0 0.14 0.2863 0.952 3011181 CMLD2_000674 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C03 compound treatment 385854.0 -56500.0 -0.34 402636.0 -15400.0 -0.09 -0.2997 -0.8623 3131874 CMLD2_000675 CO[C@@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C04 compound treatment 457509.0 15100.0 0.09 420350.0 2330.0 0.01 0.0731 0.8026 3131875 CMLD2_000676 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C05 compound treatment 72239.0 -370000.0 -2.2 447939.0 29900.0 0.17 -1.4373 -0.6505 3012234 CMLD2_000677 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C06 compound treatment 155719.0 -287000.0 -1.71 497710.0 79700.0 0.45 -0.8858 -0.5019 3131876 CMLD2_000678 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C07 compound treatment 131548.0 -311000.0 -1.85 213924.0 -204000.0 -1.16 -2.1287 -0.9748 3131877 CMLD2_000679 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C08 compound treatment 439631.0 -2740.0 -0.02 482473.0 64500.0 0.37 0.2477 0.675 3012270 CMLD2_000680 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)cc2)c6ccc(C)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C09 compound treatment 233609.0 -209000.0 -1.24 213564.0 -204000.0 -1.16 -1.7006 -0.9995 3131878 CMLD2_000681 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C10 compound treatment 479242.0 36900.0 0.22 446574.0 28600.0 0.16 0.27 0.989 3131879 CMLD2_000682 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C11 mock treatment 455962.0 13600.0 0.08 470872.0 52900.0 0.3 0.2698 0.8666 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C12 mock treatment 433282.0 -9080.0 -0.05 407738.0 -10300.0 -0.06 -0.0796 -0.9992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C13 compound treatment 273644.0 -169000.0 -1.0 139508.0 -279000.0 -1.58 -1.83 -0.9758 3012273 CMLD2_000683 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C14 compound treatment 418155.0 -24200.0 -0.14 420961.0 2950.0 0.02 -0.09 -0.6207 3131994 CMLD2_000684 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C15 mock treatment 427471.0 -14900.0 -0.09 449517.0 31500.0 0.18 0.064 0.3201 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C16 mock treatment 436433.0 -5930.0 -0.04 439183.0 21200.0 0.12 0.0601 0.4795 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C17 compound treatment 423971.0 -18400.0 -0.11 431970.0 14000.0 0.08 -0.0213 -0.1575 3131995 CMLD2_000685 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C18 compound treatment 388782.0 -53600.0 -0.32 431636.0 13600.0 0.08 -0.1707 -0.5202 3012274 CMLD2_000686 CO[C@H](/C=N/O[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C19 compound treatment 395560.0 -46800.0 -0.28 450948.0 32900.0 0.19 -0.0646 -0.1923 3012275 CMLD2_000687 CC(=NO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C20 compound treatment 67500.0 -375000.0 -2.23 68270.0 -350000.0 -1.99 -2.9839 -0.9984 3131996 CMLD2_000688 CO/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C21 compound treatment 483292.0 40900.0 0.24 421112.0 3100.0 0.02 0.1847 0.7562 3011349 CMLD2_000689 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C22 compound treatment 435658.0 -6710.0 -0.04 507681.0 89700.0 0.51 0.3323 0.6498 3131997 CMLD2_000690 COc1ccc(OC[C@@H]2CC3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C23 mock treatment 476616.0 34200.0 0.2 212973.0 -205000.0 -1.17 -0.6804 -0.5748 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 C24 mock treatment 472711.0 30300.0 0.18 429578.0 11600.0 0.07 0.1742 0.9064 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D01 compound treatment 452527.0 10200.0 0.06 464571.0 46600.0 0.26 0.23 0.8468 3012277 CMLD2_000691 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D02 compound treatment 444444.0 2080.0 0.01 414574.0 -3440.0 -0.02 -0.0051 -0.2202 3131998 CMLD2_000692 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](CCSC)NC(=O)C\C=C\[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D03 compound treatment 361092.0 -81300.0 -0.48 408496.0 -9520.0 -0.05 -0.3803 -0.7814 3012278 CMLD2_000693 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)CCC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D04 compound treatment 389532.0 -52800.0 -0.31 464405.0 46400.0 0.26 -0.0358 -0.0872 3131999 CMLD2_000694 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D05 compound treatment 417382.0 -25000.0 -0.15 459775.0 41800.0 0.24 0.0628 0.2241 3132000 CMLD2_000695 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D06 compound treatment 420733.0 -21600.0 -0.13 417785.0 -231.0 0.0 -0.092 -0.7143 3012279 CMLD2_000696 CC(=O)OC[C@H]1O[C@H](C/C=N/OC2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D07 compound treatment 307524.0 -135000.0 -0.8 340703.0 -77300.0 -0.44 -0.8783 -0.9599 3132001 CMLD2_000697 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1Oc4ccc(OC)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D08 compound treatment 415630.0 -26700.0 -0.16 405292.0 -12700.0 -0.07 -0.1637 -0.9364 3132002 CMLD2_000698 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/c2ccc(cc2)C(=O)N3[C@@H](CC[C@H](C)[C@H]3c4ccc(C)cc4)C(=O)OC)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D09 compound treatment 398217.0 -44100.0 -0.26 456462.0 38400.0 0.22 -0.0312 -0.0913 3012280 CMLD2_000699 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D10 compound treatment 414559.0 -27800.0 -0.17 446553.0 28500.0 0.16 -0.0023 -0.0098 3132003 CMLD2_000700 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D11 mock treatment 413895.0 -28500.0 -0.17 424842.0 6830.0 0.04 -0.0924 -0.5314 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D12 mock treatment 430689.0 -11700.0 -0.07 418857.0 841.0 0.0 -0.0458 -0.6569 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D13 compound treatment 442082.0 -285.0 0.0 446071.0 28100.0 0.16 0.1116 0.6996 3012281 CMLD2_000701 CC1(C)O[C@H]2O[C@H]([C@H](O)CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)[C@H](O)[C@H]2O1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D14 compound treatment 67294.0 -375000.0 -2.23 80403.0 -338000.0 -1.92 -2.936 -0.9972 3132004 CMLD2_000702 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D15 mock treatment 429182.0 -13200.0 -0.08 268915.0 -149000.0 -0.85 -0.655 -0.7693 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D16 mock treatment 415262.0 -27100.0 -0.16 459079.0 41100.0 0.23 0.0511 0.1799 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D17 compound treatment 236186.0 -206000.0 -1.23 308612.0 -109000.0 -0.62 -1.3076 -0.9504 3132005 CMLD2_000703 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D18 compound treatment 408487.0 -33900.0 -0.2 505340.0 87300.0 0.5 0.2086 0.3891 3012283 CMLD2_000704 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D19 compound treatment 411081.0 -31300.0 -0.19 432491.0 14500.0 0.08 -0.0735 -0.3608 3132006 CMLD2_000705 C[C@@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D20 compound treatment 498222.0 55900.0 0.33 422590.0 4570.0 0.03 0.2534 0.7601 3012284 CMLD2_000706 CO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D21 compound treatment 399590.0 -42800.0 -0.25 399103.0 -18900.0 -0.11 -0.2561 -0.9265 3132007 CMLD2_000707 CCCC[C@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D22 compound treatment 459679.0 17300.0 0.1 419087.0 1070.0 0.01 0.0772 0.7476 3132008 CMLD2_000708 C[C@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D23 mock treatment 414718.0 -27600.0 -0.16 374892.0 -43100.0 -0.25 -0.2898 -0.9812 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 D24 mock treatment 463598.0 21200.0 0.13 419922.0 1910.0 0.01 0.097 0.765 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E01 mock treatment 416583.0 -25800.0 -0.15 426977.0 8960.0 0.05 -0.0725 -0.4482 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E02 mock treatment 433974.0 -8390.0 -0.05 431571.0 13600.0 0.08 0.0192 0.2089 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E03 compound treatment 419636.0 -22700.0 -0.14 392846.0 -25200.0 -0.14 -0.1969 -0.9996 3012286 CMLD2_000709 CO[C@@H]1COC(=O)CCC[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E04 compound treatment 225201.0 -217000.0 -1.29 447794.0 29800.0 0.17 -0.7942 -0.6093 3132009 CMLD2_000710 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E05 compound treatment 46869.0 -395000.0 -2.35 72060.0 -346000.0 -1.97 -3.0555 -0.996 3012287 CMLD2_000711 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E06 compound treatment 225909.0 -216000.0 -1.29 406972.0 -11000.0 -0.06 -0.9553 -0.7407 3132010 CMLD2_000712 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E07 compound treatment 143305.0 -299000.0 -1.78 270549.0 -147000.0 -0.84 -1.8515 -0.941 3012333 CMLD2_000713 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E08 compound treatment 287704.0 -155000.0 -0.92 341585.0 -76400.0 -0.43 -0.9582 -0.9413 3132011 CMLD2_000714 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)cc2)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E09 mock treatment 155322.0 -287000.0 -1.71 464911.0 46900.0 0.27 -1.0194 -0.5896 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E10 mock treatment 385200.0 -57200.0 -0.34 411420.0 -6600.0 -0.04 -0.2671 -0.7803 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E11 compound treatment 325005.0 -117000.0 -0.7 197727.0 -220000.0 -1.25 -1.3797 -0.9619 3012334 CMLD2_000715 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E12 compound treatment 437376.0 -4990.0 -0.03 416484.0 -1530.0 -0.01 -0.0272 -0.8775 3132012 CMLD2_000716 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E13 compound treatment 179445.0 -263000.0 -1.56 392151.0 -25900.0 -0.15 -1.2105 -0.7702 3012337 CMLD2_000717 OC[C@H]1O[C@H](CC=C)C=C[C@@H]1O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E14 compound treatment 163345.0 -279000.0 -1.66 401463.0 -16600.0 -0.09 -1.2408 -0.746 3132130 CMLD2_000718 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E15 compound treatment 439573.0 -2790.0 -0.02 304074.0 -114000.0 -0.65 -0.4699 -0.725 3132131 CMLD2_000719 CCc1cc2CN(CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E16 compound treatment 281870.0 -160000.0 -0.96 174759.0 -243000.0 -1.38 -1.6536 -0.9836 3132132 CMLD2_000720 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6)c7ccccc7)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E17 mock treatment 454630.0 12300.0 0.07 215028.0 -203000.0 -1.15 -0.7646 -0.6611 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E18 mock treatment 446895.0 4530.0 0.03 338989.0 -79000.0 -0.45 -0.2987 -0.6635 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E19 compound treatment 293937.0 -148000.0 -0.88 243949.0 -174000.0 -0.99 -1.3246 -0.9984 3012338 CMLD2_000721 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E20 mock treatment 455651.0 13300.0 0.08 217470.0 -201000.0 -1.14 -0.7505 -0.6565 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E21 compound treatment 427514.0 -14900.0 -0.09 430711.0 12700.0 0.07 -0.0115 -0.1004 3131584 CMLD2_000722 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E22 compound treatment 205199.0 -237000.0 -1.41 189810.0 -228000.0 -1.3 -1.9157 -0.9991 3012339 CMLD2_000723 COC(=O)C/C=C/[C@@H](C)[C@H](OCc1cccc(c1)c2ccccc2)C3CCCCC3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E23 mock treatment 415672.0 -26700.0 -0.16 411438.0 -6580.0 -0.04 -0.1388 -0.8503 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 E24 mock treatment 452639.0 10300.0 0.06 338959.0 -79100.0 -0.45 -0.2747 -0.6054 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F01 mock treatment 493258.0 50900.0 0.3 434344.0 16300.0 0.09 0.2798 0.8833 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F02 mock treatment 408554.0 -33800.0 -0.2 449058.0 31000.0 0.18 -0.0175 -0.0653 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F03 compound treatment 415187.0 -27200.0 -0.16 508154.0 90100.0 0.51 0.2481 0.4615 3132133 CMLD2_000724 C[C@H]1/C=C/CC(=O)OC[C@H](NS(=O)(=O)c2ccc(C)cc2)[C@@H](C)/C=C/CC(=O)OC[C@@H]1NS(=O)(=O)c3ccc(C)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F04 compound treatment 153013.0 -289000.0 -1.72 149704.0 -268000.0 -1.53 -2.2966 -0.9982 3012198 CMLD2_000725 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F05 compound treatment 470202.0 27800.0 0.17 464926.0 46900.0 0.27 0.3058 0.9737 3132134 CMLD2_000726 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F06 compound treatment 131407.0 -311000.0 -1.85 163393.0 -255000.0 -1.45 -2.3325 -0.9926 3012341 CMLD2_000727 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F07 compound treatment 346732.0 -95600.0 -0.57 350231.0 -67800.0 -0.39 -0.675 -0.982 3132135 CMLD2_000728 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F08 compound treatment 101448.0 -341000.0 -2.03 95973.0 -322000.0 -1.83 -2.7297 -0.9987 3132136 CMLD2_000729 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)cc2)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F09 mock treatment 411229.0 -31100.0 -0.19 398504.0 -19500.0 -0.11 -0.2095 -0.9699 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F10 mock treatment 420901.0 -21500.0 -0.13 405265.0 -12800.0 -0.07 -0.1416 -0.964 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F11 compound treatment 384371.0 -58000.0 -0.35 330403.0 -87600.0 -0.5 -0.5964 -0.9839 3012342 CMLD2_000730 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F12 compound treatment 387732.0 -54600.0 -0.33 78636.0 -339000.0 -1.93 -1.5946 -0.8148 3132137 CMLD2_000731 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F13 compound treatment 408214.0 -34200.0 -0.2 402219.0 -15800.0 -0.09 -0.2072 -0.9326 3010880 CMLD2_000732 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F14 compound treatment 465960.0 23600.0 0.14 540539.0 123000.0 0.7 0.592 0.8329 3012343 CMLD2_000733 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F15 compound treatment 78893.0 -363000.0 -2.16 79215.0 -339000.0 -1.93 -2.892 -0.9983 3132138 CMLD2_000734 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F16 compound treatment 314139.0 -128000.0 -0.76 330192.0 -87800.0 -0.5 -0.8928 -0.9789 3132139 CMLD2_000735 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1Oc6ccc(OC)cc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F17 mock treatment 434108.0 -8260.0 -0.05 421422.0 3410.0 0.02 -0.0211 -0.3986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F18 mock treatment 409288.0 -33100.0 -0.2 407590.0 -10400.0 -0.06 -0.1811 -0.881 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F19 compound treatment 66240.0 -376000.0 -2.24 67261.0 -351000.0 -1.99 -2.9933 -0.9983 3012344 CMLD2_000736 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F20 mock treatment 440634.0 -1730.0 -0.01 426427.0 8410.0 0.05 0.0265 0.5422 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F21 compound treatment 407655.0 -34700.0 -0.21 396606.0 -21400.0 -0.12 -0.2322 -0.9682 3012345 CMLD2_000737 C[C@@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F22 compound treatment 423359.0 -19000.0 -0.11 379062.0 -39000.0 -0.22 -0.2366 -0.9513 3132140 CMLD2_000738 CO[C@@H]([C@H](C)/C=C/CC(=O)OCCCc1ccccc1)C2CCCCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F23 mock treatment 368933.0 -73400.0 -0.44 415646.0 -2370.0 -0.01 -0.3186 -0.7286 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 F24 mock treatment 469511.0 27100.0 0.16 442090.0 24100.0 0.14 0.211 0.9966 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G01 compound treatment 417663.0 -24700.0 -0.15 460636.0 42600.0 0.24 0.0674 0.2378 3132141 CMLD2_000739 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G02 compound treatment 459686.0 17300.0 0.1 402348.0 -15700.0 -0.09 0.0099 0.0725 3012346 CMLD2_000740 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G03 mock treatment 412139.0 -30200.0 -0.18 413027.0 -4990.0 -0.03 -0.1473 -0.8086 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G04 mock treatment 452886.0 10500.0 0.06 403784.0 -14200.0 -0.08 -0.013 -0.1267 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G05 compound treatment 393053.0 -49300.0 -0.29 341393.0 -76600.0 -0.44 -0.5156 -0.9815 3132142 CMLD2_000741 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G06 compound treatment 43487.0 -399000.0 -2.37 174839.0 -243000.0 -1.38 -2.6564 -0.9669 3012347 CMLD2_000742 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G07 mock treatment 125685.0 -317000.0 -1.88 136772.0 -281000.0 -1.6 -2.4636 -0.9967 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G08 mock treatment 443116.0 749.0 0.0 297668.0 -120000.0 -0.68 -0.4808 -0.7025 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G09 compound treatment 441427.0 -940.0 -0.01 471723.0 53700.0 0.31 0.212 0.694 3132143 CMLD2_000743 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G10 compound treatment 439013.0 -3350.0 -0.02 397847.0 -20200.0 -0.11 -0.0952 -0.8179 3132144 CMLD2_000744 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C\3/[C@H](O)[C@H](Oc4ccc(OC)cc34)c5cccc(OC)c5)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G11 compound treatment 445916.0 3550.0 0.02 283720.0 -134000.0 -0.76 -0.5251 -0.6873 3132145 CMLD2_000745 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G12 compound treatment 265109.0 -177000.0 -1.05 402799.0 -15200.0 -0.09 -0.8071 -0.7625 3012401 CMLD2_000746 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G13 compound treatment 424862.0 -17500.0 -0.1 364412.0 -53600.0 -0.3 -0.2892 -0.8978 3132146 CMLD2_000747 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@@H]7COC[C@H]7O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G14 compound treatment 344282.0 -98100.0 -0.58 134043.0 -284000.0 -1.61 -1.5547 -0.9054 3012403 CMLD2_000748 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G15 compound treatment 131416.0 -311000.0 -1.85 145382.0 -273000.0 -1.55 -2.4049 -0.9961 3132147 CMLD2_000749 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G16 compound treatment 180303.0 -262000.0 -1.56 154567.0 -263000.0 -1.5 -2.1622 -0.9998 3012404 CMLD2_000750 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G17 compound treatment 379544.0 -62800.0 -0.37 277136.0 -141000.0 -0.8 -0.8309 -0.9398 3132148 CMLD2_000751 CO[C@H](/C=N/OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G18 compound treatment 194066.0 -248000.0 -1.48 297931.0 -120000.0 -0.68 -1.5278 -0.9385 3132267 CMLD2_000752 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CON=C(C)C)c3ccccc3)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G19 mock treatment 436717.0 -5650.0 -0.03 206741.0 -211000.0 -1.2 -0.8733 -0.7266 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G20 mock treatment 123882.0 -318000.0 -1.9 191025.0 -227000.0 -1.29 -2.253 -0.9825 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G21 compound treatment 266490.0 -176000.0 -1.05 287822.0 -130000.0 -0.74 -1.2637 -0.9856 3012405 CMLD2_000753 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G22 compound treatment 66883.0 -375000.0 -2.23 60415.0 -358000.0 -2.03 -3.0181 -0.9989 3132268 CMLD2_000754 CO[C@H]([C@@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)CO)C2CCCCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G23 mock treatment 473063.0 30700.0 0.18 401971.0 -16000.0 -0.09 0.0647 0.3166 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 G24 mock treatment 457695.0 15300.0 0.09 294534.0 -123000.0 -0.7 -0.432 -0.6101 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H01 compound treatment 419470.0 -22900.0 -0.14 466525.0 48500.0 0.28 0.0987 0.3208 3012408 CMLD2_000755 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H02 compound treatment 434012.0 -8350.0 -0.05 459001.0 41000.0 0.23 0.1296 0.544 3132269 CMLD2_000756 C[C@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H03 mock treatment 439716.0 -2650.0 -0.02 400727.0 -17300.0 -0.1 -0.0807 -0.8102 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H04 mock treatment 399862.0 -42500.0 -0.25 435696.0 17700.0 0.1 -0.1078 -0.3959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H05 compound treatment 506460.0 64100.0 0.38 352844.0 -65200.0 -0.37 0.0077 0.0144 3132270 CMLD2_000757 CC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H06 compound treatment 428034.0 -14300.0 -0.09 378377.0 -39600.0 -0.23 -0.2197 -0.9116 3012411 CMLD2_000758 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCCCc4nc(C)c(C)cc34 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H07 mock treatment 430240.0 -12100.0 -0.07 435894.0 17900.0 0.1 0.0209 0.1673 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H08 compound treatment 473294.0 30900.0 0.18 249877.0 -168000.0 -0.96 -0.546 -0.5607 3132271 CMLD2_000759 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)cc2)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H09 compound treatment 429256.0 -13100.0 -0.08 437659.0 19600.0 0.11 0.0238 0.1748 3132272 CMLD2_000760 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H10 compound treatment 386317.0 -56000.0 -0.33 430185.0 12200.0 0.07 -0.1869 -0.5487 3012412 CMLD2_000761 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C\2/[C@H](O)[C@H](Oc3ccc(OC)cc23)c4cccc(OC)c4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H11 compound treatment 420397.0 -22000.0 -0.13 418089.0 73.1 0.0 -0.0922 -0.7049 3132273 CMLD2_000762 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H12 compound treatment 166475.0 -276000.0 -1.64 269756.0 -148000.0 -0.84 -1.7572 -0.952 3132274 CMLD2_000763 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H13 compound treatment 379731.0 -62600.0 -0.37 383309.0 -34700.0 -0.2 -0.4032 -0.9558 3012414 CMLD2_000764 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H14 compound treatment 318769.0 -124000.0 -0.74 287194.0 -131000.0 -0.74 -1.0462 -1.0 3132275 CMLD2_000765 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)COCc2ccco2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H15 compound treatment 478204.0 35800.0 0.21 106694.0 -311000.0 -1.77 -1.1011 -0.6175 3012415 CMLD2_000766 CCc1cc2CN(CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H16 compound treatment 197315.0 -245000.0 -1.46 221466.0 -197000.0 -1.12 -1.8216 -0.9914 3132276 CMLD2_000767 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H17 compound treatment 318878.0 -123000.0 -0.73 322843.0 -95200.0 -0.54 -0.9024 -0.9887 3132277 CMLD2_000768 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc2ccc(OC)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H18 compound treatment 411367.0 -31000.0 -0.18 353378.0 -64600.0 -0.37 -0.3904 -0.9492 3012416 CMLD2_000769 CCCNC(=O)OC[C@H]1O[C@H](CCON=C(C)C)C=C[C@@H]1Oc2ccc(OC)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H19 mock treatment 226606.0 -216000.0 -1.28 261430.0 -157000.0 -0.89 -1.5376 -0.984 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H20 mock treatment 425515.0 -16900.0 -0.1 404068.0 -13900.0 -0.08 -0.127 -0.9933 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H21 compound treatment 79911.0 -362000.0 -2.16 218322.0 -200000.0 -1.14 -2.3283 -0.9551 3132278 CMLD2_000770 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H22 compound treatment 127069.0 -315000.0 -1.88 161999.0 -256000.0 -1.46 -2.3563 -0.9921 3012418 CMLD2_000771 CO[C@H]1[C@H](C)/C(=C\CCOCC#CC)/c2ccccc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H23 mock treatment 144643.0 -298000.0 -1.77 128622.0 -289000.0 -1.65 -2.4166 -0.9993 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 H24 mock treatment 469328.0 27000.0 0.16 449740.0 31700.0 0.18 0.241 0.9983 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I01 compound treatment 491437.0 49100.0 0.29 451036.0 33000.0 0.19 0.3393 0.9772 3132279 CMLD2_000772 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I02 compound treatment 424104.0 -18300.0 -0.11 534468.0 116000.0 0.66 0.3914 0.5833 3012419 CMLD2_000773 C[C@@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I03 compound treatment 276810.0 -166000.0 -0.99 231966.0 -186000.0 -1.06 -1.4448 -0.9994 3132280 CMLD2_000774 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)c6ccccc6)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I04 compound treatment 378263.0 -64100.0 -0.38 405370.0 -12600.0 -0.07 -0.3206 -0.8259 3132281 CMLD2_000775 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I05 mock treatment 434035.0 -8330.0 -0.05 422669.0 4650.0 0.03 -0.0164 -0.2909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I06 mock treatment 398969.0 -43400.0 -0.26 420427.0 2410.0 0.01 -0.1729 -0.6686 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I07 compound treatment 202145.0 -240000.0 -1.43 164476.0 -254000.0 -1.44 -2.0304 -1.0 3012420 CMLD2_000776 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I08 compound treatment 391628.0 -50700.0 -0.3 326675.0 -91300.0 -0.52 -0.5808 -0.9667 3132282 CMLD2_000777 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)cc2)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I09 compound treatment 337575.0 -105000.0 -0.62 258960.0 -159000.0 -0.9 -1.0806 -0.9835 3012421 CMLD2_000778 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I10 compound treatment 496729.0 54400.0 0.32 471778.0 53800.0 0.31 0.445 0.9996 3132283 CMLD2_000779 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I11 compound treatment 205216.0 -237000.0 -1.41 173598.0 -244000.0 -1.39 -1.9808 -1.0 3012422 CMLD2_000780 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@H]4O[C@@H](C=C[C@@H]4Oc5ccc(OC)cc5)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I12 compound treatment 147822.0 -295000.0 -1.75 404603.0 -13400.0 -0.08 -1.2935 -0.7372 3012473 CMLD2_000781 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I13 compound treatment 70425.0 -372000.0 -2.21 73685.0 -344000.0 -1.96 -2.9498 -0.9981 3132284 CMLD2_000782 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cc(no6)c7c(C)cc(C)cc7C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I14 compound treatment 480947.0 38600.0 0.23 383547.0 -34500.0 -0.2 0.0238 0.0787 3012475 CMLD2_000783 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I15 compound treatment 438567.0 -3800.0 -0.02 241176.0 -177000.0 -1.01 -0.7271 -0.7228 3132285 CMLD2_000784 CCc1cc2CN(CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I16 compound treatment 84972.0 -357000.0 -2.13 71167.0 -347000.0 -1.97 -2.8987 -0.9993 3012476 CMLD2_000785 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I17 compound treatment 448244.0 5880.0 0.03 258795.0 -159000.0 -0.91 -0.6155 -0.6793 3132408 CMLD2_000786 CO[C@H](/C=N/OCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I18 compound treatment 439002.0 -3360.0 -0.02 242726.0 -175000.0 -1.0 -0.719 -0.7212 3012477 CMLD2_000787 CC(=NOCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I19 compound treatment 372319.0 -70000.0 -0.42 219582.0 -198000.0 -1.13 -1.0927 -0.9083 3132409 CMLD2_000788 CO/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I20 mock treatment 283772.0 -159000.0 -0.94 176092.0 -242000.0 -1.38 -1.6402 -0.9831 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I21 mock treatment 436192.0 -6170.0 -0.04 345521.0 -72500.0 -0.41 -0.3175 -0.7671 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I22 mock treatment 466123.0 23800.0 0.14 267072.0 -151000.0 -0.86 -0.507 -0.5828 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I23 mock treatment 420661.0 -21700.0 -0.13 472460.0 54400.0 0.31 0.1276 0.3803 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 I24 mock treatment 461555.0 19200.0 0.11 489665.0 71600.0 0.41 0.3689 0.8717 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J01 compound treatment 487116.0 44700.0 0.27 417970.0 -45.9 0.0 0.1881 0.7064 3132410 CMLD2_000789 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)CCC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J02 compound treatment 438927.0 -3440.0 -0.02 391242.0 -26800.0 -0.15 -0.1221 -0.795 3012478 CMLD2_000790 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J03 compound treatment 298913.0 -143000.0 -0.85 242289.0 -176000.0 -1.0 -1.3103 -0.9969 3132411 CMLD2_000791 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J04 compound treatment 99063.0 -343000.0 -2.04 89157.0 -329000.0 -1.87 -2.7671 -0.999 3132412 CMLD2_000792 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J05 mock treatment 435887.0 -6480.0 -0.04 417913.0 -103.0 0.0 -0.0277 -0.7178 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J06 mock treatment 292499.0 -150000.0 -0.89 428523.0 10500.0 0.06 -0.5884 -0.6583 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J07 compound treatment 264347.0 -178000.0 -1.06 277916.0 -140000.0 -0.8 -1.3125 -0.9901 3012479 CMLD2_000793 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J08 compound treatment 384578.0 -57800.0 -0.34 149090.0 -269000.0 -1.53 -1.3246 -0.845 3012480 CMLD2_000794 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)COCc3ccco3)cc2)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J09 compound treatment 230295.0 -212000.0 -1.26 249045.0 -169000.0 -0.96 -1.5719 -0.9909 3132413 CMLD2_000795 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J10 compound treatment 326611.0 -116000.0 -0.69 286326.0 -132000.0 -0.75 -1.0167 -0.9991 3132414 CMLD2_000796 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCCc5nc(C)c(C)cc45)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J11 compound treatment 316352.0 -126000.0 -0.75 150318.0 -268000.0 -1.52 -1.6068 -0.9468 3132415 CMLD2_000797 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(CC)C4=O)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J12 compound treatment 322495.0 -120000.0 -0.71 338451.0 -79600.0 -0.45 -0.8244 -0.9759 3012481 CMLD2_000798 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J13 compound treatment 110851.0 -332000.0 -1.97 89074.0 -329000.0 -1.87 -2.7178 -0.9996 3132416 CMLD2_000799 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J14 compound treatment 382395.0 -60000.0 -0.36 414834.0 -3180.0 -0.02 -0.2652 -0.742 3012482 CMLD2_000800 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J15 compound treatment 427596.0 -14800.0 -0.09 297112.0 -121000.0 -0.69 -0.5483 -0.7911 3132417 CMLD2_000801 CCc1cc2CN(CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J16 compound treatment 127714.0 -315000.0 -1.87 71180.0 -347000.0 -1.97 -2.7188 -0.9997 3012484 CMLD2_000802 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J17 compound treatment 319196.0 -123000.0 -0.73 114116.0 -304000.0 -1.73 -1.7404 -0.9271 3132418 CMLD2_000803 CO[C@H](/C=N/OC(C)CN1CCCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J18 compound treatment 500635.0 58300.0 0.35 282506.0 -136000.0 -0.77 -0.2997 -0.3547 3012486 CMLD2_000804 CC(CN1CCCCc2nc(C)c(C)cc12)ON=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J19 compound treatment 321549.0 -121000.0 -0.72 481369.0 63400.0 0.36 -0.2537 -0.3154 3132419 CMLD2_000805 CO/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J20 mock treatment 434375.0 -7990.0 -0.05 442677.0 24700.0 0.14 0.0655 0.4425 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J21 mock treatment 424397.0 -18000.0 -0.11 448219.0 30200.0 0.17 0.0458 0.2265 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J22 mock treatment 431925.0 -10400.0 -0.06 461433.0 43400.0 0.25 0.1306 0.5131 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J23 mock treatment 179385.0 -263000.0 -1.57 430996.0 13000.0 0.07 -1.0545 -0.673 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 J24 mock treatment 397998.0 -44400.0 -0.26 508952.0 90900.0 0.52 0.179 0.3082 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K01 compound treatment 444935.0 2570.0 0.02 452508.0 34500.0 0.2 0.1495 0.7599 3132420 CMLD2_000806 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K02 compound treatment 462153.0 19800.0 0.12 426911.0 8900.0 0.05 0.119 0.9288 3012487 CMLD2_000807 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K03 compound treatment 392244.0 -50100.0 -0.3 241927.0 -176000.0 -1.0 -0.919 -0.8796 3132421 CMLD2_000808 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K04 compound treatment 174915.0 -267000.0 -1.59 162574.0 -255000.0 -1.45 -2.1527 -0.999 3132422 CMLD2_000809 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K05 compound treatment 425243.0 -17100.0 -0.1 459928.0 41900.0 0.24 0.0965 0.3722 3012488 CMLD2_000810 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K06 compound treatment 467934.0 25600.0 0.15 509336.0 91300.0 0.52 0.4748 0.8774 3132423 CMLD2_000811 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K07 mock treatment 452529.0 10200.0 0.06 410230.0 -7790.0 -0.04 0.0115 0.1529 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K08 mock treatment 473206.0 30800.0 0.18 405934.0 -12100.0 -0.07 0.0812 0.4143 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K09 compound treatment 501946.0 59600.0 0.35 471343.0 53300.0 0.3 0.4652 0.997 3132424 CMLD2_000812 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K10 compound treatment 475655.0 33300.0 0.2 456863.0 38800.0 0.22 0.2963 0.9985 3011824 CMLD2_000813 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCc5nc(C)c(C)cc45)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K11 compound treatment 460947.0 18600.0 0.11 412653.0 -5360.0 -0.03 0.0566 0.4937 3132425 CMLD2_000814 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K12 compound treatment 72658.0 -370000.0 -2.2 62935.0 -355000.0 -2.02 -2.9837 -0.9991 3132426 CMLD2_000815 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)c8ccccc8)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K13 compound treatment 394293.0 -48100.0 -0.29 445243.0 27200.0 0.15 -0.0928 -0.2853 3011825 CMLD2_000816 CC(=O)OC[C@H]1O[C@@H](O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K14 compound treatment 491213.0 48800.0 0.29 536507.0 118000.0 0.67 0.682 0.9294 3132547 CMLD2_000817 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K15 mock treatment 463465.0 21100.0 0.13 143270.0 -275000.0 -1.56 -1.016 -0.6482 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K16 mock treatment 453718.0 11400.0 0.07 438588.0 20600.0 0.12 0.1305 0.9659 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K17 compound treatment 458632.0 16300.0 0.1 412352.0 -5660.0 -0.03 0.0457 0.4477 3011826 CMLD2_000818 CO[C@H](/C=N/OC(C)CN1CCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K18 compound treatment 408686.0 -33700.0 -0.2 394261.0 -23800.0 -0.14 -0.2373 -0.9816 3132548 CMLD2_000819 CC(CN1CCCc2nc(C)c(C)cc12)ON=C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K19 compound treatment 256556.0 -186000.0 -1.11 223545.0 -194000.0 -1.11 -1.5639 -1.0 3011827 CMLD2_000820 CO/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K20 compound treatment 380905.0 -61500.0 -0.37 455835.0 37800.0 0.22 -0.1066 -0.2512 3131977 CMLD2_000821 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K21 compound treatment 353104.0 -89300.0 -0.53 364560.0 -53500.0 -0.3 -0.5906 -0.9649 3132549 CMLD2_000822 C[C@@H]1CC[C@@H]2N(C[C@H](Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K22 compound treatment 475732.0 33400.0 0.2 398056.0 -20000.0 -0.11 0.0601 0.263 3132550 CMLD2_000823 CCO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K23 mock treatment 495600.0 53200.0 0.32 440225.0 22200.0 0.13 0.3133 0.9187 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 K24 mock treatment 452814.0 10400.0 0.06 489515.0 71500.0 0.41 0.3315 0.8059 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L01 compound treatment 456509.0 14100.0 0.08 429216.0 11200.0 0.06 0.1046 0.9905 3011828 CMLD2_000824 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L02 compound treatment 421258.0 -21100.0 -0.13 358334.0 -59700.0 -0.34 -0.3288 -0.9086 3132551 CMLD2_000825 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L03 compound treatment 283440.0 -159000.0 -0.95 248965.0 -169000.0 -0.96 -1.3486 -1.0 3011829 CMLD2_000826 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L04 compound treatment 117954.0 -324000.0 -1.93 216355.0 -202000.0 -1.15 -2.1761 -0.9691 3132552 CMLD2_000827 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L05 compound treatment 99840.0 -343000.0 -2.04 44622.0 -373000.0 -2.12 -2.9429 -0.9998 3132553 CMLD2_000828 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L06 compound treatment 451722.0 9360.0 0.06 428250.0 10200.0 0.06 0.0805 0.9998 3011830 CMLD2_000829 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L07 mock treatment 433121.0 -9250.0 -0.06 507206.0 89200.0 0.51 0.3197 0.6267 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L08 mock treatment 412116.0 -30300.0 -0.18 450325.0 32300.0 0.18 0.0026 0.0102 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L09 compound treatment 482014.0 39600.0 0.24 169326.0 -249000.0 -1.41 -0.8332 -0.5811 3132554 CMLD2_000830 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)COCc2ccco2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L10 compound treatment 433608.0 -8760.0 -0.05 383886.0 -34100.0 -0.19 -0.1741 -0.8663 3011831 CMLD2_000831 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L11 compound treatment 451585.0 9220.0 0.05 427457.0 9440.0 0.05 0.0768 0.9999 3132555 CMLD2_000832 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCCc5nc(C)c(C)cc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L12 compound treatment 229385.0 -213000.0 -1.27 184855.0 -233000.0 -1.33 -1.8339 -0.9997 3132556 CMLD2_000833 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1Oc7ccc(OC)cc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L13 compound treatment 372764.0 -69600.0 -0.41 375795.0 -42200.0 -0.24 -0.4627 -0.9664 3011832 CMLD2_000834 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L14 compound treatment 477757.0 35400.0 0.21 448139.0 30100.0 0.17 0.2701 0.9947 3132557 CMLD2_000835 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L15 mock treatment 430167.0 -12200.0 -0.07 491865.0 73800.0 0.42 0.2456 0.5763 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L16 mock treatment 470566.0 28200.0 0.17 249145.0 -169000.0 -0.96 -0.5604 -0.5748 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L17 compound treatment 435623.0 -6740.0 -0.04 188236.0 -230000.0 -1.31 -0.9524 -0.7285 3132558 CMLD2_000836 CO[C@H](/C=N/OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L18 compound treatment 426865.0 -15500.0 -0.09 406321.0 -11700.0 -0.07 -0.1123 -0.9871 3011833 CMLD2_000837 CC(=NOC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L19 compound treatment 506830.0 64500.0 0.38 434033.0 16000.0 0.09 0.3357 0.8513 3011834 CMLD2_000838 CO/N=C/c1ccc(cc1)C(=O)N2[C@@H](CC[C@H](C)[C@H]2c3ccc(C)cc3)C(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L20 compound treatment 407197.0 -35200.0 -0.21 409123.0 -8890.0 -0.05 -0.1838 -0.8534 3132559 CMLD2_000839 CCC(=O)[C@]1(O)[C@H]2CCOC(=O)C2=C3N(Cc4ccccc4)C(=C([C@H](N3C1=O)c5ccccc5)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L21 compound treatment 344626.0 -97700.0 -0.58 321969.0 -96000.0 -0.55 -0.7975 -0.9995 3132529 CMLD2_000840 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L22 compound treatment 496142.0 53800.0 0.32 480999.0 63000.0 0.36 0.4796 0.9984 3011835 CMLD2_000841 CO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)C(=O)C)[C@@H](C)[C@H](OC)c1ccccc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L23 mock treatment 164283.0 -278000.0 -1.65 468428.0 50400.0 0.29 -0.9675 -0.576 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 L24 mock treatment 453602.0 11200.0 0.07 527997.0 110000.0 0.63 0.4895 0.7783 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M01 compound treatment 310951.0 -131000.0 -0.78 414664.0 -3350.0 -0.02 -0.5665 -0.7241 3132560 CMLD2_000842 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)CCC[C@H]1C)[C@@H](O)C=C2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M02 compound treatment 453529.0 11200.0 0.07 373876.0 -44100.0 -0.25 -0.1305 -0.5027 3011836 CMLD2_000843 C[C@H]/1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C\C=C1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M03 compound treatment 305809.0 -137000.0 -0.81 262143.0 -156000.0 -0.89 -1.2015 -0.9991 3132561 CMLD2_000844 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M04 compound treatment 471823.0 29500.0 0.18 524238.0 106000.0 0.6 0.5511 0.8762 3132562 CMLD2_000845 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M05 compound treatment 478027.0 35700.0 0.21 503462.0 85400.0 0.49 0.4937 0.931 3011870 CMLD2_000846 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M06 compound treatment 470033.0 27700.0 0.16 460371.0 42400.0 0.24 0.2867 0.9828 3132563 CMLD2_000847 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M07 compound treatment 187726.0 -255000.0 -1.52 516788.0 98800.0 0.56 -0.6744 -0.4173 3011871 CMLD2_000848 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M08 compound treatment 511484.0 69100.0 0.41 513113.0 95100.0 0.54 0.6733 0.9909 3132564 CMLD2_000849 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)cc2)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M09 mock treatment 500987.0 58600.0 0.35 462486.0 44500.0 0.25 0.4255 0.9875 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M10 mock treatment 498764.0 56400.0 0.34 456255.0 38200.0 0.22 0.3911 0.9779 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M11 compound treatment 177481.0 -265000.0 -1.58 253044.0 -165000.0 -0.94 -1.7781 -0.9693 3011872 CMLD2_000850 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCc5nc(C)c(C)cc45 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M12 compound treatment 397393.0 -45000.0 -0.27 272230.0 -146000.0 -0.83 -0.7755 -0.8902 3132565 CMLD2_000851 CC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M13 mock treatment 461305.0 18900.0 0.11 343462.0 -74600.0 -0.42 -0.2201 -0.5017 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M14 mock treatment 481692.0 39300.0 0.23 233888.0 -184000.0 -1.05 -0.5749 -0.5358 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M15 compound treatment 487502.0 45100.0 0.27 506572.0 88600.0 0.5 0.546 0.9567 3132566 CMLD2_000852 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M16 compound treatment 152466.0 -290000.0 -1.73 134198.0 -284000.0 -1.61 -2.3613 -0.9994 3011873 CMLD2_000853 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M17 compound treatment 492422.0 50100.0 0.3 486518.0 68500.0 0.39 0.4861 0.9912 3130490 CMLD2_000854 CO[C@H](/C=N/O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M18 compound treatment 466397.0 24000.0 0.14 456393.0 38400.0 0.22 0.2554 0.979 3011875 CMLD2_000855 CC(=NOC1C=C[C@@H](CC=C)O[C@@H]1CO)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M19 compound treatment 486224.0 43900.0 0.26 511557.0 93500.0 0.53 0.5607 0.9463 3130491 CMLD2_000856 CO/N=C/[C@@H](NS(=O)(=O)c1ccc(C)cc1)[C@H](C)\C=C\CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M20 compound treatment 454002.0 11600.0 0.07 488304.0 70300.0 0.4 0.3316 0.8174 3132404 CMLD2_000857 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M21 compound treatment 483976.0 41600.0 0.25 461244.0 43200.0 0.25 0.3489 1.0 3011876 CMLD2_000858 C[C@H]1CC[C@@H]2N(C[C@@H](CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M22 compound treatment 412904.0 -29500.0 -0.18 410548.0 -7470.0 -0.04 -0.154 -0.8537 3130492 CMLD2_000859 CO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1ccccc1Br 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M23 mock treatment 492649.0 50300.0 0.3 411142.0 -6870.0 -0.04 0.184 0.6096 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 M24 mock treatment 452839.0 10500.0 0.06 480768.0 62800.0 0.36 0.2964 0.8182 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N01 compound treatment 446694.0 4330.0 0.03 347020.0 -71000.0 -0.4 -0.2673 -0.6607 3130493 CMLD2_000860 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)CCC[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N02 compound treatment 426064.0 -16300.0 -0.1 397503.0 -20500.0 -0.12 -0.1511 -0.9958 3011877 CMLD2_000861 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N03 compound treatment 435746.0 -6620.0 -0.04 462805.0 44800.0 0.25 0.1522 0.5907 3130494 CMLD2_000862 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)c5ccccc5)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N04 compound treatment 358192.0 -84200.0 -0.5 364992.0 -53000.0 -0.3 -0.5674 -0.9705 3130495 CMLD2_000863 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N05 compound treatment 432342.0 -10000.0 -0.06 456744.0 38700.0 0.22 0.1135 0.4976 3011878 CMLD2_000864 CC(=O)OC[C@H]1O[C@H](C/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N06 compound treatment 470520.0 28200.0 0.17 466389.0 48400.0 0.28 0.313 0.9717 3130496 CMLD2_000865 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N07 compound treatment 448018.0 5650.0 0.03 494090.0 76100.0 0.43 0.3297 0.7598 3011879 CMLD2_000866 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N08 compound treatment 283971.0 -158000.0 -0.94 233001.0 -185000.0 -1.05 -1.4105 -0.9985 3130497 CMLD2_000867 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N09 mock treatment 435064.0 -7300.0 -0.04 466114.0 48100.0 0.27 0.1627 0.5874 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N10 mock treatment 541081.0 98700.0 0.59 540687.0 123000.0 0.7 0.9087 0.9963 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N11 compound treatment 452718.0 10400.0 0.06 503540.0 85500.0 0.49 0.3875 0.7904 3011881 CMLD2_000868 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N12 compound treatment 363136.0 -79200.0 -0.47 310227.0 -108000.0 -0.61 -0.7669 -0.9916 3130498 CMLD2_000869 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N13 mock treatment 416063.0 -26300.0 -0.16 428018.0 10000.0 0.06 -0.0705 -0.4231 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N14 mock treatment 456738.0 14400.0 0.09 456193.0 38200.0 0.22 0.214 0.9171 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N15 compound treatment 548147.0 106000.0 0.63 488953.0 70900.0 0.4 0.7304 0.9769 3130499 CMLD2_000870 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N16 compound treatment 398391.0 -44000.0 -0.26 391238.0 -26800.0 -0.15 -0.2927 -0.9668 3011882 CMLD2_000871 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N17 compound treatment 450317.0 7950.0 0.05 458156.0 40100.0 0.23 0.1949 0.8359 3130500 CMLD2_000872 CO[C@H](/C=N/OC[C@@H](O)COCc1ccco1)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N18 compound treatment 454658.0 12300.0 0.07 452680.0 34700.0 0.2 0.1911 0.9089 3011884 CMLD2_000873 CC(=NOC[C@@H](O)COCc1ccco1)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N19 compound treatment 370212.0 -72200.0 -0.43 390144.0 -27900.0 -0.16 -0.4157 -0.9082 3130501 CMLD2_000874 CO/N=C\1/[C@H](O)[C@H](Oc2ccc(OC)cc12)c3cccc(OC)c3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N20 compound treatment 515598.0 73200.0 0.44 482701.0 64700.0 0.37 0.5683 0.9964 3131849 CMLD2_000875 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N21 compound treatment 464300.0 21900.0 0.13 455765.0 37700.0 0.21 0.2441 0.9716 3011885 CMLD2_000876 C[C@@H]1CC[C@@H]2N(C[C@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N22 compound treatment 137349.0 -305000.0 -1.82 200662.0 -217000.0 -1.24 -2.1576 -0.9825 3130502 CMLD2_000877 CO[C@@H]([C@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)/C=C/CC(=O)OC)C2CCCCC2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N23 mock treatment 463152.0 20800.0 0.12 445452.0 27400.0 0.16 0.1978 0.9934 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 N24 mock treatment 459839.0 17500.0 0.1 469881.0 51900.0 0.29 0.2821 0.902 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O01 compound treatment 446724.0 4360.0 0.03 296941.0 -121000.0 -0.69 -0.4685 -0.68 3011886 CMLD2_000878 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O02 compound treatment 350751.0 -91600.0 -0.55 438418.0 20400.0 0.12 -0.3035 -0.5445 3130503 CMLD2_000879 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O03 compound treatment 230822.0 -212000.0 -1.26 163571.0 -254000.0 -1.45 -1.9134 -0.9976 3130504 CMLD2_000880 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O04 compound treatment 123461.0 -319000.0 -1.9 154366.0 -264000.0 -1.5 -2.4022 -0.9932 3130505 CMLD2_000881 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O05 compound treatment 521977.0 79600.0 0.47 291047.0 -127000.0 -0.72 -0.1755 -0.2033 3130506 CMLD2_000882 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)COCc2ccco2)C=C[C@@H]1OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O06 compound treatment 86720.0 -356000.0 -2.12 68736.0 -349000.0 -1.99 -2.9012 -0.9995 3011921 CMLD2_000883 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O07 compound treatment 340213.0 -102000.0 -0.61 374905.0 -43100.0 -0.25 -0.6032 -0.9202 3130507 CMLD2_000884 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O08 compound treatment 447915.0 5550.0 0.03 272858.0 -145000.0 -0.83 -0.5604 -0.6783 3130508 CMLD2_000885 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)cc2)c5ccc(C)cc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O09 compound treatment 340631.0 -102000.0 -0.61 552148.0 134000.0 0.76 0.1112 0.1142 3011922 CMLD2_000886 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O10 compound treatment 465349.0 23000.0 0.14 476938.0 58900.0 0.34 0.3337 0.9219 3130509 CMLD2_000887 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O11 mock treatment 449326.0 6960.0 0.04 569078.0 151000.0 0.86 0.6367 0.7403 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O12 mock treatment 467648.0 25300.0 0.15 490900.0 72900.0 0.41 0.3995 0.906 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O13 compound treatment 472779.0 30400.0 0.18 523612.0 106000.0 0.6 0.5526 0.8811 3011925 CMLD2_000888 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/[C@@H](C)[C@H](OCc3ccccc3)C(C)C)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O14 compound treatment 493690.0 51300.0 0.31 516878.0 98900.0 0.56 0.6135 0.9589 3130636 CMLD2_000889 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O15 compound treatment 70626.0 -372000.0 -2.21 72164.0 -346000.0 -1.97 -2.9551 -0.9983 3011927 CMLD2_000890 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O16 compound treatment 449177.0 6810.0 0.04 475220.0 57200.0 0.33 0.2587 0.7891 3130637 CMLD2_000891 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@@H]6COC[C@H]6O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O17 compound treatment 468056.0 25700.0 0.15 494360.0 76300.0 0.43 0.4151 0.9018 3130638 CMLD2_000892 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@@H]2COC[C@H]2O)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O18 compound treatment 396293.0 -46100.0 -0.27 478548.0 60500.0 0.34 0.0495 0.1125 3011928 CMLD2_000893 C[C@@H](ON=C(C)C)c1cn(nn1)[C@@H]2COC[C@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O19 compound treatment 362417.0 -79900.0 -0.48 475246.0 57200.0 0.33 -0.1063 -0.1844 3130639 CMLD2_000894 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O20 compound treatment 454414.0 12000.0 0.07 489632.0 71600.0 0.41 0.3387 0.819 3011929 CMLD2_000895 CCN1C(=C([C@H](N2C(=O)[C@@](O)(CC(=C12)C(=O)C)C(=O)OC)c3ccccc3)C(=O)OC)C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O21 compound treatment 478023.0 35700.0 0.21 484895.0 66900.0 0.38 0.419 0.962 3130640 CMLD2_000896 C[C@@H]1CC[C@@H]2N(C[C@@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O22 mock treatment 448212.0 5850.0 0.03 466085.0 48100.0 0.27 0.2179 0.7907 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O23 mock treatment 476645.0 34300.0 0.2 406463.0 -11600.0 -0.07 0.0978 0.4563 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 O24 mock treatment 419266.0 -23100.0 -0.14 494038.0 76000.0 0.43 0.2085 0.4596 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P01 compound treatment 396174.0 -46200.0 -0.27 415710.0 -2310.0 -0.01 -0.2037 -0.74 3011930 CMLD2_000897 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P02 compound treatment 366500.0 -75900.0 -0.45 396197.0 -21800.0 -0.12 -0.407 -0.8692 3130641 CMLD2_000898 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P03 compound treatment 203233.0 -239000.0 -1.42 199207.0 -219000.0 -1.24 -1.8862 -0.9978 3130642 CMLD2_000899 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)c4ccccc4)cc1 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P04 compound treatment 248106.0 -194000.0 -1.16 231712.0 -186000.0 -1.06 -1.5667 -0.999 3130643 CMLD2_000900 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@@H]5COC[C@H]5O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P05 compound treatment 493970.0 51600.0 0.31 518473.0 100000.0 0.57 0.6211 0.9576 3011932 CMLD2_000901 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P06 compound treatment 207700.0 -235000.0 -1.4 290447.0 -128000.0 -0.73 -1.5005 -0.9535 3130644 CMLD2_000902 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P07 compound treatment 118107.0 -324000.0 -1.93 167405.0 -251000.0 -1.43 -2.3723 -0.9889 3011933 CMLD2_000903 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P08 compound treatment 328801.0 -114000.0 -0.68 495008.0 77000.0 0.44 -0.1683 -0.209 3130645 CMLD2_000904 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)cc2)c4ccc(C)cc4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P09 compound treatment 475667.0 33300.0 0.2 522524.0 105000.0 0.59 0.5604 0.8945 3011935 CMLD2_000905 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P10 compound treatment 516584.0 74200.0 0.44 506346.0 88300.0 0.5 0.6675 0.9979 3130646 CMLD2_000906 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)COCc4ccco4)/[C@@H]2O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P11 mock treatment 511694.0 69300.0 0.41 546766.0 129000.0 0.73 0.8095 0.9632 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P12 mock treatment 465498.0 23100.0 0.14 434077.0 16100.0 0.09 0.1619 0.9801 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P13 compound treatment 403698.0 -38700.0 -0.23 468795.0 50800.0 0.29 0.0415 0.1123 3130647 CMLD2_000907 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P14 compound treatment 406416.0 -36000.0 -0.21 407909.0 -10100.0 -0.06 -0.1919 -0.8663 3011936 CMLD2_000908 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P15 compound treatment 192815.0 -250000.0 -1.49 182752.0 -235000.0 -1.34 -1.9962 -0.9986 3130648 CMLD2_000909 CCc1cc2CN(CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)CCc2nc1CC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P16 compound treatment 379620.0 -62700.0 -0.37 396069.0 -21900.0 -0.12 -0.3523 -0.8948 3130649 CMLD2_000910 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P17 compound treatment 460102.0 17700.0 0.11 487458.0 69400.0 0.39 0.3539 0.8657 3011937 CMLD2_000911 CO[C@H](/C=N/O[C@@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P18 compound treatment 412707.0 -29700.0 -0.18 494292.0 76300.0 0.43 0.1819 0.3884 3130650 CMLD2_000912 C[C@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P19 compound treatment 391998.0 -50400.0 -0.3 418318.0 302.0 0.0 -0.2108 -0.703 3011939 CMLD2_000913 CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P20 compound treatment 394763.0 -47600.0 -0.28 414786.0 -3230.0 -0.02 -0.2133 -0.7514 3131985 CMLD2_000914 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P21 compound treatment 488849.0 46500.0 0.28 488674.0 70700.0 0.4 0.4797 0.9834 3130651 CMLD2_000915 C[C@@H]1CC[C@@H]2N(C[C@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P22 mock treatment 469495.0 27100.0 0.16 472844.0 54800.0 0.31 0.3346 0.9531 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P23 mock treatment 462946.0 20600.0 0.12 483123.0 65100.0 0.37 0.3484 0.8934 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.2111 P24 mock treatment 517773.0 75400.0 0.45 541511.0 123000.0 0.7 0.8139 0.9766 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A01 mock treatment 323596.0 -129000.0 -0.77 478981.0 -14000.0 -0.08 -0.5983 -0.7766 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A02 mock treatment 454089.0 1740.0 0.01 554024.0 61000.0 0.35 0.2526 0.7278 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A03 mock treatment 435060.0 -17300.0 -0.1 484249.0 -8770.0 -0.05 -0.108 -0.9446 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A04 mock treatment 390577.0 -61800.0 -0.37 442459.0 -50600.0 -0.29 -0.4633 -0.9926 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A05 mock treatment 462450.0 10100.0 0.06 493657.0 642.0 0.0 0.0451 0.7487 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A06 mock treatment 476714.0 24400.0 0.14 546365.0 53300.0 0.3 0.317 0.9429 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A07 mock treatment 375151.0 -77200.0 -0.46 354094.0 -139000.0 -0.79 -0.8835 -0.9667 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A08 mock treatment 411337.0 -41000.0 -0.24 477864.0 -15200.0 -0.09 -0.2335 -0.9021 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A09 mock treatment 539756.0 87400.0 0.52 80484.0 -413000.0 -2.35 -1.291 -0.5373 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A10 mock treatment 501320.0 49000.0 0.29 476400.0 -16600.0 -0.09 0.1393 0.4545 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A11 mock treatment 484144.0 31800.0 0.19 550186.0 57200.0 0.33 0.3637 0.9668 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A12 mock treatment 483815.0 31500.0 0.19 516469.0 23500.0 0.13 0.2267 0.9862 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A13 mock treatment 456366.0 4010.0 0.02 503949.0 10900.0 0.06 0.0609 0.9136 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A14 mock treatment 519620.0 67300.0 0.4 490030.0 -2990.0 -0.02 0.2711 0.6765 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A15 mock treatment 428831.0 -23500.0 -0.14 522954.0 29900.0 0.17 0.0214 0.0971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A16 mock treatment 485043.0 32700.0 0.19 514180.0 21200.0 0.12 0.2227 0.9734 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A17 mock treatment 471669.0 19300.0 0.11 503304.0 10300.0 0.06 0.1227 0.9509 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A18 mock treatment 405514.0 -46800.0 -0.28 638745.0 146000.0 0.83 0.3889 0.4448 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A19 mock treatment 429080.0 -23300.0 -0.14 564787.0 71800.0 0.41 0.1907 0.4424 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A20 mock treatment 307598.0 -145000.0 -0.86 538772.0 45800.0 0.26 -0.4252 -0.4725 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A21 mock treatment 281819.0 -171000.0 -1.01 588775.0 95800.0 0.54 -0.3326 -0.2888 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A22 mock treatment 153801.0 -299000.0 -1.78 500502.0 7490.0 0.04 -1.2263 -0.69 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A23 mock treatment 146218.0 -306000.0 -1.82 592321.0 99300.0 0.56 -0.889 -0.4661 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base A24 mock treatment 91733.0 -361000.0 -2.15 484114.0 -8900.0 -0.05 -1.5534 -0.7236 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B01 mock treatment 428373.0 -24000.0 -0.14 550649.0 57600.0 0.33 0.1308 0.366 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B02 mock treatment 510862.0 58500.0 0.35 634838.0 142000.0 0.81 0.8165 0.9295 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B03 mock treatment 518336.0 66000.0 0.39 470431.0 -22600.0 -0.13 0.1869 0.4523 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B04 mock treatment 480254.0 27900.0 0.17 503785.0 10800.0 0.06 0.1607 0.9081 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B05 mock treatment 437559.0 -14800.0 -0.09 532543.0 39500.0 0.22 0.0967 0.4005 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B06 mock treatment 480110.0 27800.0 0.17 517101.0 24100.0 0.14 0.2137 0.9957 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B07 mock treatment 446611.0 -5740.0 -0.03 502818.0 9800.0 0.06 0.0153 0.2333 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B08 mock treatment 435869.0 -16500.0 -0.1 529954.0 36900.0 0.21 0.0792 0.3415 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B09 mock treatment 496051.0 43700.0 0.26 463648.0 -29400.0 -0.17 0.0658 0.2129 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B10 mock treatment 406997.0 -45400.0 -0.27 519258.0 26200.0 0.15 -0.0853 -0.2767 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B11 mock treatment 445238.0 -7120.0 -0.04 596768.0 104000.0 0.59 0.3873 0.6547 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B12 mock treatment 434702.0 -17700.0 -0.11 543391.0 50400.0 0.29 0.1283 0.4204 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B13 mock treatment 437397.0 -15000.0 -0.09 562815.0 69800.0 0.4 0.2177 0.5352 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B14 mock treatment 379093.0 -73300.0 -0.44 481474.0 -11500.0 -0.07 -0.3547 -0.8045 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B15 mock treatment 427257.0 -25100.0 -0.15 495941.0 2930.0 0.02 -0.0938 -0.6245 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B16 mock treatment 430789.0 -21600.0 -0.13 477365.0 -15700.0 -0.09 -0.1537 -0.984 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B17 mock treatment 392679.0 -59700.0 -0.36 460742.0 -32300.0 -0.18 -0.3809 -0.9528 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B18 mock treatment 460432.0 8080.0 0.05 477256.0 -15800.0 -0.09 -0.0294 -0.2888 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B19 mock treatment 448313.0 -4040.0 -0.02 439088.0 -53900.0 -0.31 -0.2339 -0.7602 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B20 mock treatment 428863.0 -23500.0 -0.14 493111.0 95.6 0.0 -0.0985 -0.7044 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B21 mock treatment 378969.0 -73400.0 -0.44 463398.0 -29600.0 -0.17 -0.4279 -0.9142 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B22 mock treatment 237026.0 -215000.0 -1.28 455916.0 -37100.0 -0.21 -1.0553 -0.8126 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B23 mock treatment 182584.0 -270000.0 -1.61 498461.0 5450.0 0.03 -1.1134 -0.6933 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base B24 mock treatment 123550.0 -329000.0 -1.96 559787.0 66800.0 0.38 -1.1152 -0.5595 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C01 mock treatment 509323.0 57000.0 0.34 475638.0 -17400.0 -0.1 0.1699 0.481 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C02 mock treatment 410845.0 -41500.0 -0.25 456680.0 -36300.0 -0.21 -0.3208 -0.9961 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C03 mock treatment 538889.0 86500.0 0.52 287153.0 -206000.0 -1.17 -0.4636 -0.3625 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C04 mock treatment 558841.0 106000.0 0.63 410180.0 -82800.0 -0.47 0.115 0.1457 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C05 mock treatment 529224.0 76900.0 0.46 403175.0 -89800.0 -0.51 -0.0378 -0.0551 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C06 mock treatment 401660.0 -50700.0 -0.3 506093.0 13100.0 0.07 -0.1607 -0.5173 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C07 mock treatment 528489.0 76100.0 0.45 495547.0 2530.0 0.01 0.3306 0.7292 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C08 mock treatment 469100.0 16700.0 0.1 545816.0 52800.0 0.3 0.2828 0.8939 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C09 mock treatment 469461.0 17100.0 0.1 463213.0 -29800.0 -0.17 -0.0478 -0.242 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C10 mock treatment 427245.0 -25100.0 -0.15 429314.0 -63700.0 -0.36 -0.3618 -0.9233 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C11 mock treatment 437038.0 -15300.0 -0.09 500895.0 7880.0 0.04 -0.0328 -0.3226 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C12 mock treatment 343556.0 -109000.0 -0.65 439870.0 -53100.0 -0.3 -0.6716 -0.9398 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C13 mock treatment 471272.0 18900.0 0.11 327196.0 -166000.0 -0.94 -0.5872 -0.6183 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C14 mock treatment 501489.0 49100.0 0.29 502192.0 9180.0 0.05 0.2437 0.8203 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C15 mock treatment 480333.0 28000.0 0.17 449790.0 -43200.0 -0.25 -0.0561 -0.1888 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C16 mock treatment 405623.0 -46700.0 -0.28 390585.0 -102000.0 -0.58 -0.6085 -0.9428 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C17 mock treatment 435001.0 -17400.0 -0.1 424340.0 -68700.0 -0.39 -0.3492 -0.8644 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C18 mock treatment 320816.0 -132000.0 -0.78 446807.0 -46200.0 -0.26 -0.7394 -0.8954 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C19 mock treatment 460237.0 7880.0 0.05 505853.0 12800.0 0.07 0.0848 0.9772 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C20 mock treatment 369625.0 -82700.0 -0.49 422862.0 -70200.0 -0.4 -0.6302 -0.9946 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C21 mock treatment 268963.0 -183000.0 -1.09 466801.0 -26200.0 -0.15 -0.8772 -0.7963 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C22 mock treatment 269002.0 -183000.0 -1.09 535881.0 42900.0 0.24 -0.5992 -0.5359 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C23 mock treatment 255007.0 -197000.0 -1.17 524303.0 31300.0 0.18 -0.7047 -0.5932 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base C24 mock treatment 186198.0 -266000.0 -1.58 542960.0 49900.0 0.28 -0.9192 -0.5712 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D01 mock treatment 422357.0 -30000.0 -0.18 504774.0 11800.0 0.07 -0.079 -0.4141 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D02 mock treatment 460559.0 8210.0 0.05 491897.0 -1120.0 -0.01 0.03 0.6099 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D03 mock treatment 528376.0 76000.0 0.45 473865.0 -19200.0 -0.11 0.2429 0.522 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D04 mock treatment 543464.0 91100.0 0.54 512624.0 19600.0 0.11 0.4623 0.835 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D05 mock treatment 487456.0 35100.0 0.21 534137.0 41100.0 0.23 0.3131 0.9984 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D06 mock treatment 435268.0 -17100.0 -0.1 516873.0 23900.0 0.14 0.024 0.1418 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D07 mock treatment 447307.0 -5050.0 -0.03 479462.0 -13600.0 -0.08 -0.0757 -0.9156 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D08 mock treatment 452036.0 -317.0 0.0 462648.0 -30400.0 -0.17 -0.1234 -0.7148 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D09 mock treatment 434565.0 -17800.0 -0.11 656822.0 164000.0 0.93 0.5838 0.6227 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D10 mock treatment 404351.0 -48000.0 -0.29 450870.0 -42100.0 -0.24 -0.3715 -0.9962 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D11 mock treatment 430526.0 -21800.0 -0.13 442213.0 -50800.0 -0.29 -0.2961 -0.9349 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D12 mock treatment 413790.0 -38600.0 -0.23 455182.0 -37800.0 -0.22 -0.3144 -0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D13 mock treatment 420358.0 -32000.0 -0.19 414324.0 -78700.0 -0.45 -0.4511 -0.9275 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D14 mock treatment 478421.0 26100.0 0.16 455398.0 -37600.0 -0.21 -0.0416 -0.1573 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D15 mock treatment 377654.0 -74700.0 -0.44 436922.0 -56100.0 -0.32 -0.5399 -0.9867 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D16 mock treatment 360310.0 -92000.0 -0.55 434608.0 -58400.0 -0.33 -0.6222 -0.9713 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D17 mock treatment 357608.0 -94700.0 -0.56 409001.0 -84000.0 -0.48 -0.7365 -0.9966 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D18 mock treatment 413579.0 -38800.0 -0.23 415353.0 -77700.0 -0.44 -0.4755 -0.9542 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D19 mock treatment 487376.0 35000.0 0.21 404445.0 -88600.0 -0.5 -0.2088 -0.383 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D20 mock treatment 444826.0 -7530.0 -0.04 445630.0 -47400.0 -0.27 -0.2222 -0.8135 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D21 mock treatment 390056.0 -62300.0 -0.37 467400.0 -25600.0 -0.15 -0.3652 -0.9167 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D22 mock treatment 295113.0 -157000.0 -0.94 468869.0 -24100.0 -0.14 -0.7588 -0.8023 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D23 mock treatment 247078.0 -205000.0 -1.22 443449.0 -49600.0 -0.28 -1.0632 -0.848 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base D24 mock treatment 304042.0 -148000.0 -0.88 507599.0 14600.0 0.08 -0.5655 -0.6379 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E01 mock treatment 497793.0 45400.0 0.27 546901.0 53900.0 0.31 0.4079 0.9981 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E02 mock treatment 538810.0 86500.0 0.51 518276.0 25300.0 0.14 0.4654 0.8712 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E03 mock treatment 499492.0 47100.0 0.28 437860.0 -55200.0 -0.31 -0.0234 -0.0556 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E04 mock treatment 477897.0 25500.0 0.15 471844.0 -21200.0 -0.12 0.0224 0.1153 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E05 mock treatment 412009.0 -40300.0 -0.24 517378.0 24400.0 0.14 -0.0718 -0.2591 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E06 mock treatment 260358.0 -192000.0 -1.14 473786.0 -19200.0 -0.11 -0.8853 -0.7713 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E07 mock treatment 408185.0 -44200.0 -0.26 439176.0 -53800.0 -0.31 -0.4024 -0.9971 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E08 mock treatment 465278.0 12900.0 0.08 436872.0 -56100.0 -0.32 -0.1714 -0.5218 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E09 mock treatment 413052.0 -39300.0 -0.23 342343.0 -151000.0 -0.86 -0.7713 -0.8684 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E10 mock treatment 286472.0 -166000.0 -0.99 478135.0 -14900.0 -0.08 -0.7579 -0.7649 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E11 mock treatment 413330.0 -39000.0 -0.23 258126.0 -235000.0 -1.34 -1.1087 -0.8178 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E12 mock treatment 389289.0 -63100.0 -0.38 446501.0 -46500.0 -0.26 -0.4524 -0.9853 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E13 mock treatment 288904.0 -163000.0 -0.97 444984.0 -48000.0 -0.27 -0.881 -0.8719 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E14 mock treatment 387136.0 -65200.0 -0.39 426366.0 -66600.0 -0.38 -0.5425 -0.9999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E15 mock treatment 461432.0 9080.0 0.05 478536.0 -14500.0 -0.08 -0.02 -0.2033 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E16 mock treatment 410031.0 -42300.0 -0.25 512486.0 19500.0 0.11 -0.0998 -0.3628 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E17 mock treatment 452151.0 -202.0 0.0 466949.0 -26100.0 -0.15 -0.1057 -0.7128 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E18 mock treatment 405271.0 -47100.0 -0.28 485360.0 -7660.0 -0.04 -0.2289 -0.8073 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E19 mock treatment 435992.0 -16400.0 -0.1 443344.0 -49700.0 -0.28 -0.2686 -0.8989 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E20 mock treatment 296550.0 -156000.0 -0.93 519238.0 26200.0 0.15 -0.5502 -0.5859 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E21 mock treatment 332078.0 -120000.0 -0.72 522629.0 29600.0 0.17 -0.3871 -0.5264 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E22 mock treatment 581396.0 129000.0 0.77 479902.0 -13100.0 -0.07 0.4903 0.6355 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E23 mock treatment 442897.0 -9460.0 -0.06 510456.0 17400.0 0.1 0.0303 0.266 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base E24 mock treatment 234739.0 -218000.0 -1.3 595811.0 103000.0 0.58 -0.5024 -0.3536 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F01 mock treatment 157712.0 -295000.0 -1.75 570334.0 77300.0 0.44 -0.929 -0.5139 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F02 mock treatment 492332.0 40000.0 0.24 440986.0 -52000.0 -0.3 -0.041 -0.1079 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F03 mock treatment 378165.0 -74200.0 -0.44 573640.0 80600.0 0.46 0.012 0.0188 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F04 mock treatment 419788.0 -32600.0 -0.19 592378.0 99400.0 0.57 0.2625 0.4394 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F05 mock treatment 293417.0 -159000.0 -0.95 459260.0 -33800.0 -0.19 -0.8046 -0.8336 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F06 mock treatment 383246.0 -69100.0 -0.41 476562.0 -16500.0 -0.09 -0.357 -0.8463 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F07 mock treatment 290089.0 -162000.0 -0.97 528257.0 35200.0 0.2 -0.5411 -0.5487 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F08 mock treatment 452533.0 180.0 0.0 491344.0 -1670.0 -0.01 -0.006 -0.6236 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F09 mock treatment 431718.0 -20600.0 -0.12 537153.0 44100.0 0.25 0.0906 0.3244 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F10 mock treatment 457398.0 5040.0 0.03 474109.0 -18900.0 -0.11 -0.0548 -0.4909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F11 mock treatment 331627.0 -121000.0 -0.72 474116.0 -18900.0 -0.11 -0.584 -0.8039 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F12 mock treatment 357559.0 -94800.0 -0.56 426039.0 -67000.0 -0.38 -0.6682 -0.9817 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F13 mock treatment 465970.0 13600.0 0.08 560142.0 67100.0 0.38 0.3272 0.8385 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F14 mock treatment 219491.0 -233000.0 -1.39 466794.0 -26200.0 -0.15 -1.0854 -0.7787 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F15 mock treatment 407242.0 -45100.0 -0.27 469316.0 -23700.0 -0.13 -0.2851 -0.9492 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F16 mock treatment 259858.0 -192000.0 -1.15 418882.0 -74100.0 -0.42 -1.1082 -0.9078 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F17 mock treatment 263719.0 -189000.0 -1.12 457993.0 -35000.0 -0.2 -0.9347 -0.8198 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F18 mock treatment 439897.0 -12500.0 -0.07 448584.0 -44400.0 -0.25 -0.2311 -0.8776 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F19 mock treatment 450950.0 -1400.0 -0.01 401039.0 -92000.0 -0.52 -0.3758 -0.7183 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F20 mock treatment 501755.0 49400.0 0.29 449912.0 -43100.0 -0.25 0.0346 0.0903 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F21 mock treatment 514473.0 62100.0 0.37 455432.0 -37600.0 -0.21 0.1103 0.2583 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F22 mock treatment 350216.0 -102000.0 -0.61 469324.0 -23700.0 -0.13 -0.5251 -0.8434 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F23 mock treatment 409070.0 -43300.0 -0.26 423263.0 -69800.0 -0.4 -0.4626 -0.9781 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base F24 mock treatment 396306.0 -56000.0 -0.33 530959.0 37900.0 0.22 -0.0833 -0.2096 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G01 mock treatment 400740.0 -51600.0 -0.31 575668.0 82700.0 0.47 0.1152 0.2051 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G02 mock treatment 452180.0 -173.0 0.0 519507.0 26500.0 0.15 0.1058 0.7022 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G03 mock treatment 405654.0 -46700.0 -0.28 470671.0 -22300.0 -0.13 -0.2864 -0.9371 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G04 mock treatment 381352.0 -71000.0 -0.42 474175.0 -18800.0 -0.11 -0.3746 -0.8592 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G05 mock treatment 523661.0 71300.0 0.42 441455.0 -51600.0 -0.29 0.0928 0.1798 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G06 mock treatment 552755.0 100000.0 0.6 436207.0 -56800.0 -0.32 0.1941 0.2857 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G07 mock treatment 456980.0 4630.0 0.03 447225.0 -45800.0 -0.26 -0.1647 -0.6288 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G08 mock treatment 497563.0 45200.0 0.27 459425.0 -33600.0 -0.19 0.0552 0.1672 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G09 mock treatment 452776.0 423.0 0.0 365691.0 -127000.0 -0.72 -0.5102 -0.7046 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G10 mock treatment 454257.0 1900.0 0.01 395998.0 -97000.0 -0.55 -0.3821 -0.6924 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G11 mock treatment 400226.0 -52100.0 -0.31 461555.0 -31500.0 -0.18 -0.3459 -0.9658 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G12 mock treatment 375518.0 -76800.0 -0.46 474826.0 -18200.0 -0.1 -0.3965 -0.8457 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G13 mock treatment 480825.0 28500.0 0.17 467230.0 -25800.0 -0.15 0.0161 0.072 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G14 mock treatment 406711.0 -45600.0 -0.27 477428.0 -15600.0 -0.09 -0.2548 -0.8916 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G15 mock treatment 483984.0 31600.0 0.19 408214.0 -84800.0 -0.48 -0.2079 -0.4016 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G16 mock treatment 454058.0 1700.0 0.01 486382.0 -6630.0 -0.04 -0.0195 -0.4992 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G17 mock treatment 451785.0 -568.0 0.0 486454.0 -6560.0 -0.04 -0.0288 -0.7681 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G18 mock treatment 443264.0 -9090.0 -0.05 448792.0 -44200.0 -0.25 -0.2161 -0.84 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G19 mock treatment 421231.0 -31100.0 -0.19 391916.0 -101000.0 -0.57 -0.5375 -0.8899 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G20 mock treatment 471891.0 19500.0 0.12 452969.0 -40000.0 -0.23 -0.0788 -0.3082 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G21 mock treatment 492650.0 40300.0 0.24 413594.0 -79400.0 -0.45 -0.1498 -0.2929 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G22 mock treatment 440695.0 -11700.0 -0.07 453495.0 -39500.0 -0.22 -0.208 -0.8842 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G23 mock treatment 387344.0 -65000.0 -0.39 470927.0 -22100.0 -0.13 -0.3624 -0.8909 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base G24 mock treatment 552695.0 100000.0 0.6 485186.0 -7830.0 -0.04 0.3908 0.6526 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H01 mock treatment 324758.0 -128000.0 -0.76 595582.0 103000.0 0.58 -0.1245 -0.13 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H02 mock treatment 477728.0 25400.0 0.15 460391.0 -32600.0 -0.19 -0.0244 -0.102 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H03 mock treatment 453527.0 1170.0 0.01 444228.0 -48800.0 -0.28 -0.1912 -0.6891 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H04 mock treatment 347361.0 -105000.0 -0.62 523017.0 30000.0 0.17 -0.3212 -0.4959 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H05 mock treatment 577561.0 125000.0 0.75 495796.0 2780.0 0.02 0.5381 0.7219 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H06 mock treatment 483546.0 31200.0 0.19 387873.0 -105000.0 -0.6 -0.2915 -0.4656 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H07 mock treatment 561104.0 109000.0 0.65 369364.0 -124000.0 -0.7 -0.0396 -0.0414 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H08 mock treatment 441508.0 -10800.0 -0.06 518074.0 25100.0 0.14 0.0551 0.3524 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H09 mock treatment 438600.0 -13800.0 -0.08 498916.0 5900.0 0.03 -0.0342 -0.386 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H10 mock treatment 437382.0 -15000.0 -0.09 482531.0 -10500.0 -0.06 -0.1052 -0.9809 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H11 mock treatment 424639.0 -27700.0 -0.16 339301.0 -154000.0 -0.87 -0.7347 -0.826 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H12 mock treatment 435430.0 -16900.0 -0.1 497973.0 4960.0 0.03 -0.0513 -0.4903 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H13 mock treatment 474246.0 21900.0 0.13 474947.0 -18100.0 -0.1 0.0195 0.1174 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H14 mock treatment 208422.0 -244000.0 -1.45 437199.0 -55800.0 -0.32 -1.251 -0.8418 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H15 mock treatment 463931.0 11600.0 0.07 408272.0 -84700.0 -0.48 -0.292 -0.5999 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H16 mock treatment 454745.0 2390.0 0.01 147161.0 -346000.0 -1.97 -1.3807 -0.702 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H17 mock treatment 211233.0 -241000.0 -1.44 409190.0 -83800.0 -0.48 -1.3518 -0.894 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H18 mock treatment 513689.0 61300.0 0.37 457648.0 -35400.0 -0.2 0.1159 0.2781 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H19 mock treatment 481598.0 29200.0 0.17 399957.0 -93100.0 -0.53 -0.2511 -0.4508 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H20 mock treatment 408824.0 -43500.0 -0.26 480145.0 -12900.0 -0.07 -0.2349 -0.8727 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H21 mock treatment 408664.0 -43700.0 -0.26 436243.0 -56800.0 -0.32 -0.4121 -0.9942 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H22 mock treatment 385508.0 -66800.0 -0.4 471737.0 -21300.0 -0.12 -0.3669 -0.8823 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H23 mock treatment 445647.0 -6710.0 -0.04 186616.0 -306000.0 -1.74 -1.2603 -0.7231 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base H24 mock treatment 428532.0 -23800.0 -0.14 87455.0 -406000.0 -2.31 -1.7311 -0.7492 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I01 mock treatment 439195.0 -13200.0 -0.08 507802.0 14800.0 0.08 0.0041 0.0356 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I02 mock treatment 484681.0 32300.0 0.19 513063.0 20000.0 0.11 0.2167 0.9688 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I03 mock treatment 587239.0 135000.0 0.8 468480.0 -24500.0 -0.14 0.469 0.5756 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I04 mock treatment 485201.0 32800.0 0.2 289923.0 -203000.0 -1.15 -0.6784 -0.5792 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I05 mock treatment 527221.0 74900.0 0.45 474365.0 -18700.0 -0.11 0.2401 0.5241 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I06 mock treatment 557619.0 105000.0 0.63 465403.0 -27600.0 -0.16 0.332 0.514 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I07 mock treatment 473179.0 20800.0 0.12 495341.0 2330.0 0.01 0.097 0.7781 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I08 mock treatment 345662.0 -107000.0 -0.63 245989.0 -247000.0 -1.4 -1.4423 -0.9356 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I09 mock treatment 482204.0 29900.0 0.18 440503.0 -52500.0 -0.3 -0.0855 -0.2462 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I10 mock treatment 441449.0 -10900.0 -0.06 448069.0 -44900.0 -0.26 -0.2266 -0.8594 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I11 mock treatment 459293.0 6940.0 0.04 445691.0 -47300.0 -0.27 -0.1611 -0.5917 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I12 mock treatment 427988.0 -24400.0 -0.15 397967.0 -95000.0 -0.54 -0.4847 -0.8662 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I13 mock treatment 367324.0 -85000.0 -0.51 408648.0 -84400.0 -0.48 -0.6971 -0.9996 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I14 mock treatment 460911.0 8560.0 0.05 446385.0 -46600.0 -0.27 -0.1515 -0.561 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I15 mock treatment 461236.0 8880.0 0.05 469336.0 -23700.0 -0.13 -0.0578 -0.3998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I16 mock treatment 519048.0 66700.0 0.4 450801.0 -42200.0 -0.24 0.1109 0.2391 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I17 mock treatment 459906.0 7550.0 0.04 447671.0 -45300.0 -0.26 -0.1506 -0.5752 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I18 mock treatment 428726.0 -23600.0 -0.14 411656.0 -81400.0 -0.46 -0.4266 -0.8822 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I19 mock treatment 400269.0 -52100.0 -0.31 441254.0 -51800.0 -0.29 -0.4273 -0.9997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I20 mock treatment 456512.0 4160.0 0.02 412130.0 -80900.0 -0.46 -0.3078 -0.6681 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I21 mock treatment 444687.0 -7670.0 -0.05 487250.0 -5770.0 -0.03 -0.0554 -0.9869 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I22 mock treatment 458998.0 6640.0 0.04 558413.0 65400.0 0.37 0.2909 0.7779 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I23 mock treatment 499907.0 47600.0 0.28 583347.0 90300.0 0.51 0.5634 0.9605 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base I24 mock treatment 452572.0 219.0 0.0 401800.0 -91200.0 -0.52 -0.3659 -0.7053 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J01 mock treatment 590308.0 138000.0 0.82 526677.0 33700.0 0.19 0.7159 0.8492 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J02 mock treatment 396215.0 -56100.0 -0.33 494834.0 1820.0 0.01 -0.2289 -0.6849 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J03 mock treatment 443058.0 -9300.0 -0.06 446082.0 -46900.0 -0.27 -0.2278 -0.8359 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J04 mock treatment 531189.0 78800.0 0.47 441161.0 -51900.0 -0.29 0.1232 0.2224 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J05 mock treatment 540534.0 88200.0 0.52 481409.0 -11600.0 -0.07 0.3244 0.6133 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J06 mock treatment 470742.0 18400.0 0.11 588568.0 95600.0 0.54 0.4616 0.8328 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J07 mock treatment 539675.0 87300.0 0.52 551578.0 58600.0 0.33 0.603 0.9769 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J08 mock treatment 433424.0 -18900.0 -0.11 528191.0 35200.0 0.2 0.0618 0.2691 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J09 mock treatment 263880.0 -188000.0 -1.12 414432.0 -78600.0 -0.45 -1.1091 -0.9186 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J10 mock treatment 481798.0 29400.0 0.18 441033.0 -52000.0 -0.3 -0.0851 -0.2477 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J11 mock treatment 452826.0 473.0 0.0 548136.0 55100.0 0.31 0.2236 0.7134 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J12 mock treatment 447797.0 -4560.0 -0.03 449523.0 -43500.0 -0.25 -0.1941 -0.78 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J13 mock treatment 433950.0 -18400.0 -0.11 433630.0 -59400.0 -0.34 -0.3162 -0.8908 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J14 mock treatment 465948.0 13600.0 0.08 452548.0 -40500.0 -0.23 -0.1055 -0.4326 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J15 mock treatment 450433.0 -1920.0 -0.01 459270.0 -33700.0 -0.19 -0.1438 -0.7479 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J16 mock treatment 447649.0 -4700.0 -0.03 464204.0 -28800.0 -0.16 -0.1357 -0.8161 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J17 mock treatment 447223.0 -5130.0 -0.03 229896.0 -263000.0 -1.5 -1.0796 -0.7214 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J18 mock treatment 152625.0 -300000.0 -1.78 451133.0 -41900.0 -0.24 -1.4298 -0.7945 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J19 mock treatment 177842.0 -275000.0 -1.63 471275.0 -21700.0 -0.12 -1.2426 -0.7584 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J20 mock treatment 182079.0 -270000.0 -1.61 482319.0 -10700.0 -0.06 -1.1804 -0.7333 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J21 mock treatment 150685.0 -302000.0 -1.8 464679.0 -28300.0 -0.16 -1.3835 -0.7675 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J22 mock treatment 444723.0 -7630.0 -0.05 517298.0 24300.0 0.14 0.0655 0.4508 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J23 mock treatment 390386.0 -62000.0 -0.37 499213.0 6200.0 0.04 -0.2359 -0.6366 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base J24 mock treatment 183224.0 -269000.0 -1.6 517879.0 24900.0 0.14 -1.0326 -0.6422 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K01 mock treatment 454987.0 2630.0 0.02 569662.0 76600.0 0.44 0.3193 0.7321 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K02 mock treatment 327721.0 -125000.0 -0.74 494051.0 1040.0 0.01 -0.5203 -0.7015 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K03 mock treatment 510707.0 58400.0 0.35 477457.0 -15600.0 -0.09 0.183 0.5106 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K04 mock treatment 542820.0 90500.0 0.54 469668.0 -23300.0 -0.13 0.2868 0.5172 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K05 mock treatment 585018.0 133000.0 0.79 453566.0 -39400.0 -0.22 0.3997 0.4869 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K06 mock treatment 487569.0 35200.0 0.21 459142.0 -33900.0 -0.19 0.012 0.0421 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K07 mock treatment 484925.0 32600.0 0.19 602635.0 110000.0 0.62 0.5779 0.8852 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K08 mock treatment 499574.0 47200.0 0.28 475132.0 -17900.0 -0.1 0.1268 0.4243 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K09 mock treatment 519260.0 66900.0 0.4 497049.0 4030.0 0.02 0.2978 0.7466 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K10 mock treatment 473415.0 21100.0 0.13 543510.0 50500.0 0.29 0.2917 0.9309 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K11 mock treatment 500443.0 48100.0 0.29 496366.0 3350.0 0.02 0.2158 0.7525 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K12 mock treatment 499127.0 46800.0 0.28 497399.0 4380.0 0.02 0.2145 0.7674 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K13 mock treatment 468330.0 16000.0 0.1 498235.0 5220.0 0.03 0.0882 0.8857 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K14 mock treatment 477142.0 24800.0 0.15 534542.0 41500.0 0.24 0.2713 0.9743 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K15 mock treatment 530429.0 78100.0 0.46 535562.0 42500.0 0.24 0.4997 0.9537 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K16 mock treatment 517380.0 65000.0 0.39 452988.0 -40000.0 -0.23 0.1127 0.251 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K17 mock treatment 481652.0 29300.0 0.17 539425.0 46400.0 0.26 0.3099 0.9798 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K18 mock treatment 516549.0 64200.0 0.38 463855.0 -29200.0 -0.17 0.1529 0.3671 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K19 mock treatment 539542.0 87200.0 0.52 472520.0 -20500.0 -0.12 0.2845 0.535 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K20 mock treatment 500059.0 47700.0 0.28 499754.0 6740.0 0.04 0.2279 0.7953 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K21 mock treatment 469618.0 17300.0 0.1 563943.0 70900.0 0.4 0.3579 0.8598 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K22 mock treatment 457041.0 4690.0 0.03 492620.0 -395.0 0.0 0.0181 0.648 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K23 mock treatment 481695.0 29300.0 0.17 503005.0 9990.0 0.06 0.1636 0.8912 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base K24 mock treatment 397742.0 -54600.0 -0.33 521550.0 28500.0 0.16 -0.1151 -0.3168 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L01 mock treatment 388338.0 -64000.0 -0.38 511702.0 18700.0 0.11 -0.1943 -0.4911 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L02 mock treatment 433498.0 -18900.0 -0.11 559818.0 66800.0 0.38 0.1893 0.4778 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L03 mock treatment 431580.0 -20800.0 -0.12 451475.0 -41500.0 -0.24 -0.2545 -0.9544 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L04 mock treatment 512483.0 60100.0 0.36 473176.0 -19800.0 -0.11 0.1733 0.4618 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L05 mock treatment 669949.0 218000.0 1.3 472951.0 -20100.0 -0.11 0.835 0.6423 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L06 mock treatment 458008.0 5650.0 0.03 548462.0 55400.0 0.32 0.2468 0.7782 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L07 mock treatment 507983.0 55600.0 0.33 531223.0 38200.0 0.22 0.3877 0.9791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L08 mock treatment 474259.0 21900.0 0.13 576675.0 83700.0 0.48 0.4286 0.8688 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L09 mock treatment 490614.0 38300.0 0.23 568610.0 75600.0 0.43 0.465 0.9558 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L10 mock treatment 409967.0 -42400.0 -0.25 605860.0 113000.0 0.64 0.2754 0.3994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L11 mock treatment 534995.0 82600.0 0.49 579606.0 86600.0 0.49 0.696 1.0 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L12 mock treatment 505106.0 52800.0 0.31 577853.0 84800.0 0.48 0.5631 0.9783 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L13 mock treatment 505692.0 53300.0 0.32 498075.0 5060.0 0.03 0.2448 0.768 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L14 mock treatment 152773.0 -300000.0 -1.78 591157.0 98100.0 0.56 -0.8661 -0.4636 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L15 mock treatment 395526.0 -56800.0 -0.34 460700.0 -32300.0 -0.18 -0.3691 -0.9589 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L16 mock treatment 527082.0 74700.0 0.44 505895.0 12900.0 0.07 0.3663 0.8126 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L17 mock treatment 469508.0 17200.0 0.1 489135.0 -3880.0 -0.02 0.0566 0.5418 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L18 mock treatment 455984.0 3630.0 0.02 601523.0 109000.0 0.62 0.4516 0.7314 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L19 mock treatment 565129.0 113000.0 0.67 478409.0 -14600.0 -0.08 0.4159 0.6149 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L20 mock treatment 496439.0 44100.0 0.26 602334.0 109000.0 0.62 0.6251 0.9264 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L21 mock treatment 512502.0 60100.0 0.36 542203.0 49200.0 0.28 0.4509 0.9926 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L22 mock treatment 465616.0 13300.0 0.08 555061.0 62000.0 0.35 0.3053 0.8444 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L23 mock treatment 423787.0 -28600.0 -0.17 625930.0 133000.0 0.76 0.4143 0.5347 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base L24 mock treatment 450242.0 -2110.0 -0.01 498693.0 5680.0 0.03 0.0139 0.4025 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M01 mock treatment 226586.0 -226000.0 -1.34 465642.0 -27400.0 -0.16 -1.0602 -0.7838 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M02 mock treatment 350279.0 -102000.0 -0.61 503606.0 10600.0 0.06 -0.387 -0.6339 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M03 mock treatment 453600.0 1250.0 0.01 508682.0 15700.0 0.09 0.0682 0.7634 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M04 mock treatment 448666.0 -3690.0 -0.02 551568.0 58600.0 0.33 0.2199 0.6591 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M05 mock treatment 628427.0 176000.0 1.05 538988.0 46000.0 0.26 0.9258 0.8572 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M06 mock treatment 529812.0 77500.0 0.46 554599.0 61600.0 0.35 0.5736 0.9908 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M07 mock treatment 426432.0 -25900.0 -0.15 568763.0 75700.0 0.43 0.1955 0.4273 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M08 mock treatment 540420.0 88100.0 0.52 570366.0 77400.0 0.44 0.6816 0.9962 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M09 mock treatment 513421.0 61100.0 0.36 215200.0 -278000.0 -1.58 -0.8601 -0.5306 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M10 mock treatment 515099.0 62700.0 0.37 584731.0 91700.0 0.52 0.6329 0.9866 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M11 mock treatment 475918.0 23600.0 0.14 555100.0 62100.0 0.35 0.3488 0.9182 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M12 mock treatment 511739.0 59400.0 0.35 253466.0 -240000.0 -1.36 -0.7134 -0.5069 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M13 mock treatment 521051.0 68700.0 0.41 560302.0 67300.0 0.38 0.5597 0.9995 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M14 mock treatment 487749.0 35400.0 0.21 497713.0 4700.0 0.03 0.1678 0.7904 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M15 mock treatment 151119.0 -301000.0 -1.79 522962.0 29900.0 0.17 -1.1473 -0.6371 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M16 mock treatment 495686.0 43300.0 0.26 533044.0 40000.0 0.23 0.3433 0.9981 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M17 mock treatment 542216.0 89900.0 0.53 459869.0 -33100.0 -0.19 0.2449 0.4318 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M18 mock treatment 529321.0 77000.0 0.46 472106.0 -20900.0 -0.12 0.2398 0.5068 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M19 mock treatment 517224.0 64900.0 0.39 452742.0 -40300.0 -0.23 0.111 0.2474 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M20 mock treatment 479743.0 27400.0 0.16 546383.0 53400.0 0.3 0.3299 0.9575 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M21 mock treatment 446326.0 -6030.0 -0.04 517555.0 24500.0 0.14 0.0733 0.5088 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M22 mock treatment 503655.0 51300.0 0.31 472308.0 -20700.0 -0.12 0.1326 0.4053 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M23 mock treatment 441973.0 -10400.0 -0.06 443628.0 -49400.0 -0.28 -0.2423 -0.8425 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base M24 mock treatment 496846.0 44500.0 0.26 582232.0 89200.0 0.51 0.546 0.954 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N01 mock treatment 427679.0 -24700.0 -0.15 557473.0 64500.0 0.37 0.1554 0.3934 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N02 mock treatment 438455.0 -13900.0 -0.08 605922.0 113000.0 0.64 0.3955 0.611 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N03 mock treatment 261700.0 -191000.0 -1.13 517102.0 24100.0 0.14 -0.7055 -0.6173 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N04 mock treatment 373660.0 -78700.0 -0.47 556630.0 63600.0 0.36 -0.0754 -0.1273 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N05 mock treatment 454331.0 1980.0 0.01 522555.0 29500.0 0.17 0.1271 0.7548 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N06 mock treatment 213345.0 -239000.0 -1.42 488814.0 -4200.0 -0.02 -1.0227 -0.7189 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N07 mock treatment 447375.0 -4980.0 -0.03 525584.0 32600.0 0.19 0.11 0.5865 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N08 mock treatment 498440.0 46100.0 0.27 511005.0 18000.0 0.1 0.2663 0.9096 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N09 mock treatment 523657.0 71300.0 0.42 558696.0 65700.0 0.37 0.5642 0.998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N10 mock treatment 587052.0 135000.0 0.8 548269.0 55300.0 0.31 0.789 0.9164 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N11 mock treatment 413407.0 -38900.0 -0.23 516294.0 23300.0 0.13 -0.0703 -0.2633 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N12 mock treatment 522074.0 69700.0 0.41 526915.0 33900.0 0.19 0.4297 0.9392 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N13 mock treatment 548165.0 95800.0 0.57 517008.0 24000.0 0.14 0.4997 0.8522 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N14 mock treatment 499143.0 46800.0 0.28 534945.0 41900.0 0.24 0.3655 0.997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N15 mock treatment 475243.0 22900.0 0.14 539742.0 46700.0 0.27 0.2842 0.9518 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N16 mock treatment 460720.0 8370.0 0.05 537930.0 44900.0 0.26 0.2158 0.8293 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N17 mock treatment 501264.0 48900.0 0.29 552810.0 59800.0 0.34 0.4463 0.997 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N18 mock treatment 516209.0 63900.0 0.38 468699.0 -24300.0 -0.14 0.1709 0.4227 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N19 mock treatment 461898.0 9540.0 0.06 495076.0 2060.0 0.01 0.0485 0.8354 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N20 mock treatment 454409.0 2060.0 0.01 521420.0 28400.0 0.16 0.1229 0.7585 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N21 mock treatment 501308.0 49000.0 0.29 455674.0 -37300.0 -0.21 0.0559 0.1549 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N22 mock treatment 453751.0 1400.0 0.01 540906.0 47900.0 0.27 0.1985 0.7284 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N23 mock treatment 446344.0 -6010.0 -0.04 485208.0 -7810.0 -0.04 -0.0567 -0.9942 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base N24 mock treatment 473515.0 21200.0 0.13 509044.0 16000.0 0.09 0.1535 0.9874 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O01 mock treatment 434797.0 -17600.0 -0.1 564750.0 71700.0 0.41 0.2146 0.5095 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O02 mock treatment 681642.0 229000.0 1.36 614581.0 122000.0 0.69 1.4537 0.9503 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O03 mock treatment 584581.0 132000.0 0.79 545591.0 52600.0 0.3 0.7679 0.9121 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O04 mock treatment 608181.0 156000.0 0.93 541442.0 48400.0 0.28 0.8505 0.8791 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O05 mock treatment 387450.0 -64900.0 -0.39 235146.0 -258000.0 -1.47 -1.3101 -0.8639 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O06 mock treatment 567363.0 115000.0 0.68 372789.0 -120000.0 -0.68 5.0E-4 6.0E-4 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O07 mock treatment 544526.0 92200.0 0.55 636015.0 143000.0 0.81 0.9629 0.9816 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O08 mock treatment 553313.0 101000.0 0.6 612437.0 119000.0 0.68 0.9051 0.9981 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O09 mock treatment 498439.0 46100.0 0.27 164596.0 -328000.0 -1.87 -1.1267 -0.5969 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O10 mock treatment 79403.0 -373000.0 -2.22 572606.0 79600.0 0.45 -1.2494 -0.5516 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O11 mock treatment 660458.0 208000.0 1.24 585263.0 92200.0 0.52 1.2467 0.9269 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O12 mock treatment 634392.0 182000.0 1.08 641456.0 148000.0 0.84 1.363 0.9924 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O13 mock treatment 505177.0 52800.0 0.31 514414.0 21400.0 0.12 0.3083 0.9147 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O14 mock treatment 546619.0 94300.0 0.56 224592.0 -268000.0 -1.53 -0.6827 -0.4198 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O15 mock treatment 555273.0 103000.0 0.61 535661.0 42600.0 0.24 0.6046 0.9178 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O16 mock treatment 137486.0 -315000.0 -1.87 470041.0 -23000.0 -0.13 -1.4174 -0.7546 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O17 mock treatment 509533.0 57200.0 0.34 577666.0 84700.0 0.48 0.581 0.9856 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O18 mock treatment 515254.0 62900.0 0.37 419798.0 -73200.0 -0.42 -0.0297 -0.0531 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O19 mock treatment 517219.0 64900.0 0.39 522182.0 29200.0 0.17 0.3903 0.9288 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O20 mock treatment 400545.0 -51800.0 -0.31 458823.0 -34200.0 -0.19 -0.3555 -0.9753 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O21 mock treatment 507830.0 55500.0 0.33 523856.0 30800.0 0.18 0.3575 0.9562 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O22 mock treatment 525107.0 72800.0 0.43 525847.0 32800.0 0.19 0.4382 0.9293 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O23 mock treatment 634276.0 182000.0 1.08 622552.0 130000.0 0.74 1.2865 0.9824 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base O24 mock treatment 597090.0 145000.0 0.86 629337.0 136000.0 0.78 1.1573 0.9986 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P01 mock treatment 465222.0 12900.0 0.08 690626.0 198000.0 1.12 0.8488 0.7535 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P02 mock treatment 688433.0 236000.0 1.41 272236.0 -221000.0 -1.26 0.1057 0.0561 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P03 mock treatment 615049.0 163000.0 0.97 627391.0 134000.0 0.76 1.225 0.9931 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P04 mock treatment 664232.0 212000.0 1.26 553296.0 60300.0 0.34 1.134 0.8678 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P05 mock treatment 630268.0 178000.0 1.06 563453.0 70400.0 0.4 1.032 0.9116 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P06 mock treatment 313236.0 -139000.0 -0.83 535657.0 42600.0 0.24 -0.414 -0.4798 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P07 mock treatment 281288.0 -171000.0 -1.02 619705.0 127000.0 0.72 -0.2105 -0.1687 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P08 mock treatment 199805.0 -253000.0 -1.5 543209.0 50200.0 0.29 -0.861 -0.5628 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P09 mock treatment 446046.0 -6310.0 -0.04 616606.0 124000.0 0.7 0.4704 0.6684 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P10 mock treatment 385995.0 -66400.0 -0.39 164136.0 -329000.0 -1.87 -1.6017 -0.8379 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P11 mock treatment 437628.0 -14700.0 -0.09 543909.0 50900.0 0.29 0.1427 0.4718 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P12 mock treatment 578176.0 126000.0 0.75 572447.0 79400.0 0.45 0.8489 0.9707 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P13 mock treatment 514820.0 62500.0 0.37 547286.0 54300.0 0.31 0.4811 0.9957 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P14 mock treatment 529748.0 77400.0 0.46 564440.0 71400.0 0.41 0.6129 0.998 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P15 mock treatment 477890.0 25500.0 0.15 517915.0 24900.0 0.14 0.2076 0.9994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P16 mock treatment 506501.0 54100.0 0.32 493457.0 442.0 0.0 0.2296 0.7126 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P17 mock treatment 502216.0 49900.0 0.3 501667.0 8650.0 0.05 0.2446 0.8132 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P18 mock treatment 501253.0 48900.0 0.29 552486.0 59500.0 0.34 0.4449 0.9972 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P19 mock treatment 508193.0 55800.0 0.33 620825.0 128000.0 0.73 0.7489 0.9371 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P20 mock treatment 454415.0 2060.0 0.01 517241.0 24200.0 0.14 0.1061 0.767 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P21 mock treatment 533538.0 81200.0 0.48 572232.0 79200.0 0.45 0.6602 0.9994 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P22 mock treatment 441548.0 -10800.0 -0.06 532273.0 39300.0 0.22 0.1124 0.4838 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P23 mock treatment 550913.0 98600.0 0.59 552909.0 59900.0 0.34 0.6556 0.9666 1033.0012 Calcein-AM(1033.0012) PKCoreAssaySet 1033.0012.Base P24 mock treatment 779637.0 327000.0 1.95 724535.0 232000.0 1.32 2.3083 0.9818