ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A01 compound treatment 662789.0 -24800.0 -0.18 586392.0 -75800.0 -0.58 -0.535 -0.8867 1965040 CMLD1_000001 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A02 compound treatment 638020.0 -49500.0 -0.36 717630.0 55500.0 0.42 0.0419 0.0754 1965041 CMLD1_000002 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A03 compound treatment 598255.0 -89300.0 -0.65 597542.0 -64600.0 -0.49 -0.8088 -0.9901 1965042 CMLD1_000003 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A04 compound treatment 549730.0 -138000.0 -1.01 548467.0 -114000.0 -0.86 -1.3234 -0.997 1965043 CMLD1_000004 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A05 compound treatment 487986.0 -200000.0 -1.46 559089.0 -103000.0 -0.78 -1.5856 -0.9574 1965044 CMLD1_000005 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A06 compound treatment 560764.0 -127000.0 -0.93 615501.0 -46700.0 -0.35 -0.9062 -0.913 1965045 CMLD1_000006 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A07 compound treatment 508909.0 -179000.0 -1.31 550388.0 -112000.0 -0.85 -1.5242 -0.9782 1965046 CMLD1_000007 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A08 compound treatment 568763.0 -119000.0 -0.87 607358.0 -54800.0 -0.42 -0.9086 -0.9433 1965047 CMLD1_000008 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A09 compound treatment 561626.0 -126000.0 -0.92 677705.0 15500.0 0.12 -0.5676 -0.6114 1965048 CMLD1_000009 CCCCC=C[C@@H](NC(=O)Oc1cccc(c1)C(F)(F)F)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A10 compound treatment 576715.0 -111000.0 -0.81 604152.0 -58000.0 -0.44 -0.8847 -0.959 1965049 CMLD1_000010 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(OC)cc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A11 compound treatment 559339.0 -128000.0 -0.94 665593.0 3430.0 0.03 -0.6445 -0.6872 1965050 CMLD1_000011 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3cccs3)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A12 compound treatment 553108.0 -134000.0 -0.98 654800.0 -7360.0 -0.06 -0.7347 -0.7461 1965051 CMLD1_000012 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A13 compound treatment 558280.0 -129000.0 -0.95 613935.0 -48200.0 -0.37 -0.9275 -0.9148 1965052 CMLD1_000013 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A14 compound treatment 559273.0 -128000.0 -0.94 522106.0 -140000.0 -1.06 -1.4156 -0.998 1965053 CMLD1_000014 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A15 compound treatment 529481.0 -158000.0 -1.16 618361.0 -43800.0 -0.33 -1.0526 -0.8751 1965054 CMLD1_000015 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A16 compound treatment 668915.0 -18600.0 -0.14 667724.0 5570.0 0.04 -0.0664 -0.4658 1965055 CMLD1_000016 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A17 compound treatment 522817.0 -165000.0 -1.2 522225.0 -140000.0 -1.06 -1.6035 -0.9981 1965056 CMLD1_000017 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)C(C)(C)C)c2ccc(cc2)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A18 compound treatment 388671.0 -299000.0 -2.19 432711.0 -229000.0 -1.74 -2.7781 -0.9937 1965057 CMLD1_000018 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A19 compound treatment 589727.0 -97800.0 -0.72 565606.0 -96600.0 -0.73 -1.0245 -0.9999 1965058 CMLD1_000019 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A20 compound treatment 561889.0 -126000.0 -0.92 530065.0 -132000.0 -1.0 -1.3594 -0.999 1965059 CMLD1_000020 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A21 compound treatment 377435.0 -310000.0 -2.27 426732.0 -235000.0 -1.79 -2.8683 -0.9931 1965060 CMLD1_000021 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A22 mock treatment 561160.0 -126000.0 -0.92 731896.0 69700.0 0.53 -0.2789 -0.2618 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A23 mock treatment 559355.0 -128000.0 -0.94 599231.0 -62900.0 -0.48 -1.0009 -0.9512 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 A24 mock treatment 606890.0 -80700.0 -0.59 650019.0 -12100.0 -0.09 -0.4823 -0.8078 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B01 compound treatment 600992.0 -86600.0 -0.63 695418.0 33300.0 0.25 -0.2689 -0.3946 1965061 CMLD1_000022 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B02 compound treatment 623893.0 -63700.0 -0.47 648368.0 -13800.0 -0.1 -0.4032 -0.8451 1965062 CMLD1_000023 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B03 compound treatment 594900.0 -92600.0 -0.68 608368.0 -53800.0 -0.41 -0.768 -0.9707 1965063 CMLD1_000024 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B04 compound treatment 569502.0 -118000.0 -0.86 567086.0 -95100.0 -0.72 -1.1211 -0.9961 1965064 CMLD1_000025 CCOC(=O)N(CC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4)S(=O)(=O)c6ccc(C)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B05 compound treatment 594021.0 -93500.0 -0.68 580127.0 -82000.0 -0.62 -0.9243 -0.9989 1965065 CMLD1_000026 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B06 compound treatment 588039.0 -99500.0 -0.73 558243.0 -104000.0 -0.79 -1.0728 -0.9992 1965066 CMLD1_000027 CC(NP(=O)(c1ccccc1)c2ccccc2)C3(CC(=C)c4ccccc4)CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B07 compound treatment 623245.0 -64300.0 -0.47 547967.0 -114000.0 -0.87 -0.9459 -0.9586 1965067 CMLD1_000028 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B08 compound treatment 555555.0 -132000.0 -0.97 563052.0 -99100.0 -0.75 -1.2149 -0.9924 1965068 CMLD1_000029 COC(=O)C1(C)NCC2=C(C)C(=O)C(C)C2=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B09 compound treatment 620876.0 -66700.0 -0.49 663811.0 1650.0 0.01 -0.3359 -0.6887 1965069 CMLD1_000030 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B10 compound treatment 626615.0 -60900.0 -0.45 395840.0 -266000.0 -2.02 -1.7457 -0.8426 1965070 CMLD1_000031 COC(=O)C1(Cc2ccccc2)NCC3=C(C(C)C)C(=O)C(C)C3=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B11 compound treatment 647094.0 -40500.0 -0.3 547207.0 -115000.0 -0.87 -0.8267 -0.8966 1965071 CMLD1_000032 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B12 compound treatment 647305.0 -40200.0 -0.29 601428.0 -60700.0 -0.46 -0.5343 -0.9764 1965072 CMLD1_000033 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCc5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B13 compound treatment 637249.0 -50300.0 -0.37 654081.0 -8080.0 -0.06 -0.3035 -0.8138 1965073 CMLD1_000034 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B14 compound treatment 654260.0 -33300.0 -0.24 677130.0 15000.0 0.11 -0.0917 -0.3413 1965074 CMLD1_000035 COc1ccc(COC2OC[C@]3(C)[C@@H]4[C@H]2CCC5C(CO)C(CO)[C@@H](C)C(=C54)CN3C(=O)OC(C)(C)C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B15 compound treatment 630700.0 -56800.0 -0.42 645464.0 -16700.0 -0.13 -0.3836 -0.8827 1965075 CMLD1_000036 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B16 compound treatment 760626.0 73100.0 0.53 626078.0 -36100.0 -0.27 0.1841 0.3065 1965076 CMLD1_000037 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(F)cc5)C=C21)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B17 compound treatment 720280.0 32700.0 0.24 727276.0 65100.0 0.49 0.5191 0.9445 1965077 CMLD1_000038 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B18 compound treatment 667802.0 -19700.0 -0.14 616493.0 -45700.0 -0.35 -0.3474 -0.9245 1965078 CMLD1_000039 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B19 compound treatment 621248.0 -66300.0 -0.48 584408.0 -77800.0 -0.59 -0.7605 -0.9952 1965079 CMLD1_000040 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B20 compound treatment 622287.0 -65300.0 -0.48 621780.0 -40400.0 -0.31 -0.5544 -0.9772 1965080 CMLD1_000041 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B21 compound treatment 633669.0 -53900.0 -0.39 688597.0 26400.0 0.2 -0.1366 -0.3088 1965081 CMLD1_000042 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B22 mock treatment 682204.0 -5340.0 -0.04 627552.0 -34600.0 -0.26 -0.2135 -0.8033 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B23 mock treatment 692347.0 4800.0 0.04 752923.0 90800.0 0.69 0.5124 0.7422 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 B24 mock treatment 651540.0 -36000.0 -0.26 604037.0 -58100.0 -0.44 -0.4984 -0.9695 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C01 compound treatment 561024.0 -127000.0 -0.93 613644.0 -48500.0 -0.37 -0.9149 -0.9186 1965082 CMLD1_000043 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC1(CCC2CC1=O)C2(C)C)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C02 compound treatment 133534.0 -554000.0 -4.05 125383.0 -537000.0 -4.08 -5.7483 -1.0 1965083 CMLD1_000044 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C03 compound treatment 650811.0 -36700.0 -0.27 607990.0 -54200.0 -0.41 -0.4809 -0.9786 1965084 CMLD1_000045 CCCC=C(CCC)[C@@H](NC(=O)CCc1ccccc1)c2ccc(cc2)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C04 compound treatment 508172.0 -179000.0 -1.31 519108.0 -143000.0 -1.09 -1.696 -0.9956 1965085 CMLD1_000046 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C05 compound treatment 591432.0 -96100.0 -0.7 490595.0 -172000.0 -1.3 -1.4186 -0.958 1965086 CMLD1_000047 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C06 compound treatment 540272.0 -147000.0 -1.08 594984.0 -67200.0 -0.51 -1.1224 -0.9418 1965087 CMLD1_000048 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C07 compound treatment 363243.0 -324000.0 -2.37 336275.0 -326000.0 -2.48 -3.4276 -0.9998 1965088 CMLD1_000049 CCCCC=C[C@@H](NC(=O)CCc1ccccc1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C08 compound treatment 529445.0 -158000.0 -1.16 551570.0 -111000.0 -0.84 -1.4116 -0.9877 1965089 CMLD1_000050 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(C)onc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C09 compound treatment 455187.0 -232000.0 -1.7 490326.0 -172000.0 -1.31 -2.1246 -0.9915 1965090 CMLD1_000051 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C10 compound treatment 652342.0 -35200.0 -0.26 731626.0 69500.0 0.53 0.1911 0.3255 1965091 CMLD1_000052 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C11 compound treatment 577252.0 -110000.0 -0.81 640371.0 -21800.0 -0.17 -0.6874 -0.8348 1965092 CMLD1_000053 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccccc3)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C12 compound treatment 663166.0 -24400.0 -0.18 632548.0 -29600.0 -0.22 -0.2851 -0.9934 1965093 CMLD1_000054 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C13 compound treatment 566376.0 -121000.0 -0.89 588413.0 -73700.0 -0.56 -1.0227 -0.9755 1965094 CMLD1_000055 CCCCC=C[C@@H](NC(=O)c1ccccc1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C14 compound treatment 586545.0 -101000.0 -0.74 633764.0 -28400.0 -0.22 -0.6748 -0.877 1965095 CMLD1_000056 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C15 compound treatment 587376.0 -100000.0 -0.73 573036.0 -89100.0 -0.68 -0.9967 -0.9992 1965096 CMLD1_000057 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C16 compound treatment 664671.0 -22900.0 -0.17 685698.0 23500.0 0.18 0.0082 0.0333 1965097 CMLD1_000058 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C17 compound treatment 588008.0 -99500.0 -0.73 564234.0 -97900.0 -0.74 -1.0407 -0.9999 1965098 CMLD1_000059 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NS(=O)(=O)c3cccc4cccnc34)c5ccc(cc5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C18 compound treatment 660990.0 -26600.0 -0.19 678871.0 16700.0 0.13 -0.0475 -0.2049 1965099 CMLD1_000060 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(OC)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C19 compound treatment 625641.0 -61900.0 -0.45 630129.0 -32000.0 -0.24 -0.4922 -0.9576 1965100 CMLD1_000061 CC(C)(C)C(=O)N[C@@H](c1ccc(Cl)cc1)[C@]2(C)C[C@H]2C3CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C20 compound treatment 581603.0 -106000.0 -0.77 667879.0 5720.0 0.04 -0.5171 -0.6664 1965101 CMLD1_000062 CCCCC=C[C@@H](NC(=O)OCC#C)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C21 compound treatment 631610.0 -55900.0 -0.41 555758.0 -106000.0 -0.81 -0.8608 -0.9502 1965060 CMLD1_000063 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C22 mock treatment 619879.0 -67700.0 -0.49 664621.0 2460.0 0.02 -0.3367 -0.6799 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C23 mock treatment 618699.0 -68800.0 -0.5 593462.0 -68700.0 -0.52 -0.725 -0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 C24 mock treatment 557094.0 -130000.0 -0.95 654148.0 -8010.0 -0.06 -0.7176 -0.7507 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D01 compound treatment 597501.0 -90000.0 -0.66 489861.0 -172000.0 -1.31 -1.3912 -0.9495 1965102 CMLD1_000064 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D02 compound treatment 615595.0 -71900.0 -0.53 663316.0 1160.0 0.01 -0.3658 -0.6952 1965103 CMLD1_000065 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D03 compound treatment 569561.0 -118000.0 -0.86 579688.0 -82500.0 -0.63 -1.0531 -0.9876 1965104 CMLD1_000066 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D04 compound treatment 552436.0 -135000.0 -0.99 657938.0 -4220.0 -0.03 -0.7213 -0.7297 1965105 CMLD1_000067 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5ccccc5)CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D05 compound treatment 616104.0 -71400.0 -0.52 630965.0 -31200.0 -0.24 -0.537 -0.936 1965106 CMLD1_000068 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D06 compound treatment 565531.0 -122000.0 -0.89 529603.0 -133000.0 -1.01 -1.343 -0.9982 1965107 CMLD1_000069 CC(=O)N1CC2(CC2)CC1c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D07 compound treatment 677467.0 -10100.0 -0.07 658326.0 -3830.0 -0.03 -0.0727 -0.9174 1965108 CMLD1_000070 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D08 compound treatment 469971.0 -218000.0 -1.59 636672.0 -25500.0 -0.19 -1.262 -0.7873 1965109 CMLD1_000071 COC(=O)C1(C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D09 compound treatment 643309.0 -44200.0 -0.32 705334.0 43200.0 0.33 0.0032 0.0069 1965110 CMLD1_000072 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCn7cc(nc7C)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D10 compound treatment 637615.0 -49900.0 -0.37 614285.0 -47900.0 -0.36 -0.5154 -1.0 1965111 CMLD1_000073 COC(=O)C1(Cc2ccccc2)NCC3=C(C(=O)C(C)C3=C1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D11 compound treatment 629574.0 -58000.0 -0.42 658623.0 -3540.0 -0.03 -0.3188 -0.7504 1965112 CMLD1_000074 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D12 compound treatment 649559.0 -38000.0 -0.28 629993.0 -32200.0 -0.24 -0.3692 -0.998 1965113 CMLD1_000075 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccco5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D13 compound treatment 501127.0 -186000.0 -1.36 512433.0 -150000.0 -1.14 -1.7683 -0.9959 1965057 CMLD1_000076 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D14 compound treatment 540046.0 -147000.0 -1.08 635262.0 -26900.0 -0.2 -0.9072 -0.8264 1965114 CMLD1_000077 C[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D15 compound treatment 657486.0 -30100.0 -0.22 696144.0 34000.0 0.26 0.0271 0.08 1965115 CMLD1_000078 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D16 compound treatment 586381.0 -101000.0 -0.74 678562.0 16400.0 0.12 -0.435 -0.5798 1965116 CMLD1_000079 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(F)cc6)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D17 compound treatment 674203.0 -13300.0 -0.1 753529.0 91400.0 0.69 0.4218 0.6018 1965117 CMLD1_000080 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D18 compound treatment 656472.0 -31100.0 -0.23 685546.0 23400.0 0.18 -0.035 -0.1215 1965118 CMLD1_000081 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D19 compound treatment 768581.0 81000.0 0.59 677138.0 15000.0 0.11 0.4995 0.8278 1965119 CMLD1_000082 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D20 compound treatment 673090.0 -14500.0 -0.11 602603.0 -59600.0 -0.45 -0.3947 -0.8494 1965120 CMLD1_000083 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(C)n(C)n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D21 compound treatment 767634.0 80100.0 0.59 664339.0 2180.0 0.02 0.4259 0.7268 1965121 CMLD1_000084 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCF 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D22 mock treatment 739202.0 51700.0 0.38 700975.0 38800.0 0.29 0.4756 0.9925 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D23 mock treatment 732581.0 45000.0 0.33 624461.0 -37700.0 -0.29 0.0304 0.0696 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 D24 mock treatment 680437.0 -7110.0 -0.05 604081.0 -58100.0 -0.44 -0.3487 -0.785 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E01 compound treatment 533751.0 -154000.0 -1.12 552703.0 -109000.0 -0.83 -1.3833 -0.989 1965122 CMLD1_000085 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E02 compound treatment 551453.0 -136000.0 -1.0 578537.0 -83600.0 -0.64 -1.1529 -0.9765 1965123 CMLD1_000086 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E03 compound treatment 576185.0 -111000.0 -0.81 629605.0 -32600.0 -0.25 -0.7507 -0.8821 1965124 CMLD1_000087 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E04 compound treatment 637553.0 -50000.0 -0.37 646270.0 -15900.0 -0.12 -0.3439 -0.8931 1965125 CMLD1_000088 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E05 compound treatment 589794.0 -97800.0 -0.71 601390.0 -60800.0 -0.46 -0.8319 -0.9776 1965126 CMLD1_000089 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E06 compound treatment 572801.0 -115000.0 -0.84 552058.0 -110000.0 -0.84 -1.1848 -1.0 1965127 CMLD1_000090 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E07 compound treatment 208700.0 -479000.0 -3.5 156480.0 -506000.0 -3.84 -5.1925 -0.9989 1965128 CMLD1_000091 CCCCC=C[C@@H](NC(=O)C(C)(C)C)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E08 compound treatment 698733.0 11200.0 0.08 655559.0 -6600.0 -0.05 0.0224 0.2335 1965129 CMLD1_000092 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E09 compound treatment 547993.0 -140000.0 -1.02 510224.0 -152000.0 -1.15 -1.5378 -0.9981 1965130 CMLD1_000093 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E10 compound treatment 585827.0 -102000.0 -0.74 468798.0 -193000.0 -1.47 -1.5647 -0.9503 1965131 CMLD1_000094 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E11 compound treatment 595436.0 -92100.0 -0.67 601514.0 -60600.0 -0.46 -0.8021 -0.9828 1965060 CMLD1_000095 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)Cc3ccccc3)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E12 compound treatment 649970.0 -37600.0 -0.27 666024.0 3870.0 0.03 -0.1735 -0.628 1965132 CMLD1_000096 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccccn6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E13 compound treatment 633928.0 -53600.0 -0.39 590650.0 -71500.0 -0.54 -0.6614 -0.9872 1965133 CMLD1_000097 CCCCC=C[C@@H](NC(=O)OCc1ccccc1Cl)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E14 compound treatment 591853.0 -95700.0 -0.7 609916.0 -52200.0 -0.4 -0.7755 -0.9639 1965134 CMLD1_000098 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E15 compound treatment 608779.0 -78800.0 -0.58 616062.0 -46100.0 -0.35 -0.6549 -0.9715 1965135 CMLD1_000099 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E16 compound treatment 660622.0 -26900.0 -0.2 717131.0 55000.0 0.42 0.1561 0.338 1965136 CMLD1_000100 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cccc7ccccc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E17 compound treatment 496232.0 -191000.0 -1.4 542843.0 -119000.0 -0.91 -1.6302 -0.9779 1965137 CMLD1_000101 CC(=CC1CCCCC1)[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E18 compound treatment 625179.0 -62400.0 -0.46 578919.0 -83200.0 -0.63 -0.7696 -0.9871 1965138 CMLD1_000102 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E19 compound treatment 574520.0 -113000.0 -0.83 597137.0 -65000.0 -0.49 -0.9337 -0.9697 1965139 CMLD1_000103 C[C@]1(C[C@H]1C2CCCCC2)[C@@H](NC(=O)c3ccc(cc3)c4ccccc4)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E20 compound treatment 693173.0 5630.0 0.04 694851.0 32700.0 0.25 0.2047 0.8132 1965140 CMLD1_000104 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E21 compound treatment 675892.0 -11700.0 -0.09 670642.0 8480.0 0.06 -0.0147 -0.1375 1965141 CMLD1_000105 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccccc2)c3cccc(Cl)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E22 mock treatment 687759.0 214.0 0.0 628906.0 -33300.0 -0.25 -0.1775 -0.7027 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E23 mock treatment 588510.0 -99000.0 -0.72 608320.0 -53800.0 -0.41 -0.8013 -0.9634 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 E24 mock treatment 693754.0 6210.0 0.05 601884.0 -60300.0 -0.46 -0.2917 -0.6339 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F01 compound treatment 561338.0 -126000.0 -0.92 635482.0 -26700.0 -0.2 -0.7959 -0.8423 1965142 CMLD1_000106 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CCOCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F02 compound treatment 579038.0 -109000.0 -0.79 577003.0 -85200.0 -0.65 -1.0185 -0.9949 1965143 CMLD1_000107 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F03 compound treatment 668774.0 -18800.0 -0.14 632433.0 -29700.0 -0.23 -0.2567 -0.9715 1965144 CMLD1_000108 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC)c(OC)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F04 compound treatment 594159.0 -93400.0 -0.68 573313.0 -88800.0 -0.67 -0.9602 -1.0 1965145 CMLD1_000109 CCCC[C@H]1C[C@@H]1[C@H](NP(=O)(c2ccccc2)c3ccccc3)C4(CC(=C)c5cccc(OC)c5)CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F05 compound treatment 617639.0 -69900.0 -0.51 658858.0 -3300.0 -0.03 -0.3792 -0.7409 1965146 CMLD1_000110 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccn7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F06 compound treatment 477028.0 -211000.0 -1.54 585519.0 -76600.0 -0.58 -1.5003 -0.9115 1965147 CMLD1_000111 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F07 compound treatment 646293.0 -41300.0 -0.3 585032.0 -77100.0 -0.59 -0.6276 -0.9524 1965148 CMLD1_000112 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F08 compound treatment 477990.0 -210000.0 -1.53 623491.0 -38700.0 -0.29 -1.2913 -0.8276 1965149 CMLD1_000113 CCCCCC1=C2CNC(C)(C=C2C(C)C1=O)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F09 compound treatment 629344.0 -58200.0 -0.43 667568.0 5410.0 0.04 -0.2719 -0.6359 1965150 CMLD1_000114 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F10 compound treatment 592728.0 -94800.0 -0.69 540443.0 -122000.0 -0.92 -1.1441 -0.9899 1965151 CMLD1_000115 CCCCCC1=C2CNC(Cc3ccccc3)(C=C2C(C)C1=O)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F11 compound treatment 676258.0 -11300.0 -0.08 585867.0 -76300.0 -0.58 -0.4682 -0.7997 1965152 CMLD1_000116 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F12 compound treatment 615686.0 -71900.0 -0.53 579563.0 -82600.0 -0.63 -0.8153 -0.9961 1965153 CMLD1_000117 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F13 compound treatment 517160.0 -170000.0 -1.25 442913.0 -219000.0 -1.67 -2.0588 -0.9898 1965154 CMLD1_000118 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F14 compound treatment 660291.0 -27300.0 -0.2 656058.0 -6100.0 -0.05 -0.1737 -0.8489 1965155 CMLD1_000119 C[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F15 compound treatment 800790.0 113000.0 0.83 716220.0 54100.0 0.41 0.876 0.9476 1965156 CMLD1_000120 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F16 compound treatment 706643.0 19100.0 0.14 719928.0 57800.0 0.44 0.4091 0.8882 1965157 CMLD1_000121 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccc(cc5)C(F)(F)F)C=C21)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F17 compound treatment 637069.0 -50500.0 -0.37 559261.0 -103000.0 -0.78 -0.8138 -0.9413 1965158 CMLD1_000122 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F18 compound treatment 727971.0 40400.0 0.3 543881.0 -118000.0 -0.9 -0.4263 -0.4507 1965150 CMLD1_000123 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F19 compound treatment 732070.0 44500.0 0.33 750767.0 88600.0 0.67 0.7062 0.9445 1965159 CMLD1_000124 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCSCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F20 compound treatment 685733.0 -1810.0 -0.01 679632.0 17500.0 0.13 0.0845 0.6334 1965160 CMLD1_000125 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F21 compound treatment 725024.0 37500.0 0.27 739478.0 77300.0 0.59 0.6092 0.9398 1965161 CMLD1_000126 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(O)c(O)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F22 mock treatment 709500.0 22000.0 0.16 607472.0 -54700.0 -0.42 -0.1802 -0.4046 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F23 mock treatment 708028.0 20500.0 0.15 642235.0 -19900.0 -0.15 -0.0011 -0.0052 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 F24 mock treatment 715892.0 28300.0 0.21 589158.0 -73000.0 -0.55 -0.2456 -0.4147 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G01 compound treatment 583100.0 -104000.0 -0.76 605487.0 -56700.0 -0.43 -0.8445 -0.9632 1965162 CMLD1_000127 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(Cl)cc1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G02 compound treatment 543495.0 -144000.0 -1.05 644255.0 -17900.0 -0.14 -0.8411 -0.7918 1965163 CMLD1_000128 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCCNc7ncc(cc7Cl)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G03 compound treatment 437803.0 -250000.0 -1.83 467269.0 -195000.0 -1.48 -2.3383 -0.9946 1965164 CMLD1_000129 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccccc1)c2ccc(cc2)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G04 compound treatment 462970.0 -225000.0 -1.64 576531.0 -85600.0 -0.65 -1.6213 -0.9178 1965165 CMLD1_000130 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G05 compound treatment 480999.0 -207000.0 -1.51 542730.0 -119000.0 -0.91 -1.7096 -0.9703 1965166 CMLD1_000131 CCCC=C(CCC)[C@@H](NS(=O)(=O)CC)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G06 compound treatment 630613.0 -56900.0 -0.42 681424.0 19300.0 0.15 -0.1909 -0.4326 1965167 CMLD1_000132 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G07 compound treatment 530120.0 -157000.0 -1.15 540804.0 -121000.0 -0.92 -1.466 -0.9939 1965168 CMLD1_000133 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G08 compound treatment 563869.0 -124000.0 -0.9 532987.0 -129000.0 -0.98 -1.3334 -0.9992 1965169 CMLD1_000134 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccccc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G09 compound treatment 644730.0 -42800.0 -0.31 612262.0 -49900.0 -0.38 -0.4894 -0.9955 1965170 CMLD1_000135 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G10 compound treatment 600897.0 -86600.0 -0.63 648628.0 -13500.0 -0.1 -0.5207 -0.8112 1965171 CMLD1_000136 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)c(F)c(F)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G11 compound treatment 540730.0 -147000.0 -1.07 585097.0 -77100.0 -0.59 -1.1732 -0.9593 1965172 CMLD1_000137 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G12 compound treatment 529178.0 -158000.0 -1.16 621368.0 -40800.0 -0.31 -1.0381 -0.8658 1965173 CMLD1_000138 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G13 compound treatment 603161.0 -84400.0 -0.62 557608.0 -105000.0 -0.79 -0.998 -0.9922 1965174 CMLD1_000139 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G14 compound treatment 690849.0 3300.0 0.02 625977.0 -36200.0 -0.27 -0.1773 -0.6425 1965175 CMLD1_000140 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G15 compound treatment 636843.0 -50700.0 -0.37 674338.0 12200.0 0.09 -0.1968 -0.5149 1965176 CMLD1_000141 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G16 compound treatment 697445.0 9900.0 0.07 666563.0 4400.0 0.03 0.0749 0.9385 1965177 CMLD1_000142 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G17 compound treatment 603026.0 -84500.0 -0.62 587359.0 -74800.0 -0.57 -0.8389 -0.9991 1965178 CMLD1_000143 CC(=CC1CCCCC1)[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G18 compound treatment 681191.0 -6350.0 -0.05 674274.0 12100.0 0.09 0.0322 0.3126 1965179 CMLD1_000144 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G19 compound treatment 686763.0 -782.0 -0.01 655857.0 -6300.0 -0.05 -0.0379 -0.786 1965180 CMLD1_000145 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G20 compound treatment 705058.0 17500.0 0.13 709864.0 47700.0 0.36 0.3468 0.9023 1965181 CMLD1_000146 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G21 compound treatment 704990.0 17400.0 0.13 772169.0 110000.0 0.84 0.6812 0.8057 1965182 CMLD1_000147 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C[C@H]3CN1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G22 mock treatment 695611.0 8070.0 0.06 642210.0 -19900.0 -0.15 -0.0654 -0.4024 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G23 mock treatment 672524.0 -15000.0 -0.11 627229.0 -34900.0 -0.27 -0.2653 -0.9238 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 G24 mock treatment 578679.0 -109000.0 -0.8 673768.0 11600.0 0.09 -0.5006 -0.625 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H01 compound treatment 675202.0 -12300.0 -0.09 728241.0 66100.0 0.5 0.2912 0.5708 1965183 CMLD1_000148 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccn6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H02 compound treatment 557158.0 -130000.0 -0.95 589420.0 -72700.0 -0.55 -1.065 -0.9663 1965184 CMLD1_000149 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H03 compound treatment 581430.0 -106000.0 -0.78 670689.0 8530.0 0.06 -0.5029 -0.6458 1965185 CMLD1_000150 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H04 compound treatment 223907.0 -464000.0 -3.39 112367.0 -550000.0 -4.18 -5.3509 -0.9946 1965186 CMLD1_000151 CCCC[C@H]1C[C@@H]1[C@@H]2N(C[C@](O)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H05 compound treatment 648453.0 -39100.0 -0.29 617966.0 -44200.0 -0.34 -0.4395 -0.9968 1965187 CMLD1_000152 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7nc8ccccc8[nH]7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H06 compound treatment 577555.0 -110000.0 -0.8 572551.0 -89600.0 -0.68 -1.0501 -0.9966 1965147 CMLD1_000153 CC1N(CC(O)(CC21CC2)c3ccccc3)P(=O)(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H07 compound treatment 678829.0 -8720.0 -0.06 513451.0 -149000.0 -1.13 -0.8439 -0.7458 1965188 CMLD1_000154 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H08 compound treatment 583497.0 -104000.0 -0.76 612309.0 -49800.0 -0.38 -0.8058 -0.9481 1965189 CMLD1_000155 CCCC1(NCC2=C(C)C(=O)C(C)C2=C1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H09 compound treatment 608650.0 -78900.0 -0.58 612625.0 -49500.0 -0.38 -0.6741 -0.9786 1965190 CMLD1_000156 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H10 compound treatment 581460.0 -106000.0 -0.78 551682.0 -110000.0 -0.84 -1.142 -0.9992 1965191 CMLD1_000157 COC(=O)C1(CC(C)C)NCC2=C(C)C(=O)C(C)C2=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H11 compound treatment 629428.0 -58100.0 -0.43 622123.0 -40000.0 -0.3 -0.5156 -0.9865 1965192 CMLD1_000158 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H12 compound treatment 693094.0 5550.0 0.04 737968.0 75800.0 0.58 0.4359 0.7551 1965193 CMLD1_000159 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H13 compound treatment 646267.0 -41300.0 -0.3 545882.0 -116000.0 -0.88 -0.8381 -0.8978 1965194 CMLD1_000160 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H14 compound treatment 615037.0 -72500.0 -0.53 609262.0 -52900.0 -0.4 -0.6591 -0.9906 1965195 CMLD1_000161 C[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H15 compound treatment 660920.0 -26600.0 -0.19 734753.0 72600.0 0.55 0.2523 0.4314 1965196 CMLD1_000162 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H16 compound treatment 664179.0 -23400.0 -0.17 641537.0 -20600.0 -0.16 -0.2316 -0.9991 1965197 CMLD1_000163 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccc(cc6)C(F)(F)F)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H17 compound treatment 589684.0 -97900.0 -0.72 647442.0 -14700.0 -0.11 -0.5851 -0.8078 1965198 CMLD1_000164 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H18 compound treatment 630077.0 -57500.0 -0.42 584824.0 -77300.0 -0.59 -0.7126 -0.9865 1965199 CMLD1_000165 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CC7CC7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H19 compound treatment 649577.0 -38000.0 -0.28 618892.0 -43300.0 -0.33 -0.4288 -0.9965 1965200 CMLD1_000166 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H20 compound treatment 704941.0 17400.0 0.13 769250.0 107000.0 0.81 0.6652 0.8079 1965201 CMLD1_000167 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H21 compound treatment 714006.0 26500.0 0.19 700438.0 38300.0 0.29 0.3425 0.9804 1965202 CMLD1_000168 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H22 mock treatment 678973.0 -8570.0 -0.06 656220.0 -5940.0 -0.05 -0.0762 -0.987 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H23 mock treatment 722196.0 34700.0 0.25 619183.0 -43000.0 -0.33 -0.0517 -0.125 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 H24 mock treatment 683737.0 -3810.0 -0.03 657946.0 -4210.0 -0.03 -0.0423 -0.9976 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I01 compound treatment 563817.0 -124000.0 -0.9 581890.0 -80300.0 -0.61 -1.071 -0.9815 1965203 CMLD1_000169 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc(c1)C(F)(F)F)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I02 compound treatment 451942.0 -236000.0 -1.72 555319.0 -107000.0 -0.81 -1.7922 -0.941 1965204 CMLD1_000170 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I03 compound treatment 510209.0 -177000.0 -1.3 559396.0 -103000.0 -0.78 -1.469 -0.9705 1965205 CMLD1_000171 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I04 compound treatment 617651.0 -69900.0 -0.51 567334.0 -94800.0 -0.72 -0.8708 -0.9859 1965206 CMLD1_000172 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(OC(F)(F)F)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I05 compound treatment 132074.0 -555000.0 -4.06 138766.0 -523000.0 -3.98 -5.6839 -0.9999 1965207 CMLD1_000173 CCCC=C(CCC)[C@@H](NC(=O)c1ccco1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I06 compound treatment 716613.0 29100.0 0.21 695679.0 33500.0 0.25 0.3304 0.996 1965208 CMLD1_000174 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I07 compound treatment 549869.0 -138000.0 -1.01 677410.0 15300.0 0.12 -0.63 -0.6216 1965209 CMLD1_000175 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(F)(F)F)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I08 compound treatment 602878.0 -84700.0 -0.62 751985.0 89800.0 0.68 0.0447 0.0485 1965210 CMLD1_000176 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I09 compound treatment 505408.0 -182000.0 -1.33 467701.0 -194000.0 -1.48 -1.9864 -0.9987 1965211 CMLD1_000177 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I10 compound treatment 606565.0 -81000.0 -0.59 631165.0 -31000.0 -0.24 -0.5852 -0.9183 1965212 CMLD1_000178 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(Cl)c(c6)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I11 compound treatment 400669.0 -287000.0 -2.1 585314.0 -76800.0 -0.58 -1.8963 -0.8708 1965213 CMLD1_000179 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I12 compound treatment 599239.0 -88300.0 -0.65 593735.0 -68400.0 -0.52 -0.8242 -0.9942 1965214 CMLD1_000180 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I13 compound treatment 591178.0 -96400.0 -0.7 565327.0 -96800.0 -0.74 -1.0185 -0.9998 1965215 CMLD1_000181 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I14 compound treatment 710632.0 23100.0 0.17 690105.0 27900.0 0.21 0.2695 0.9936 1965216 CMLD1_000182 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I15 compound treatment 638474.0 -49100.0 -0.36 702851.0 40700.0 0.31 -0.0352 -0.0742 1965217 CMLD1_000183 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I16 compound treatment 672123.0 -15400.0 -0.11 704596.0 42400.0 0.32 0.1482 0.434 1965218 CMLD1_000184 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I17 compound treatment 610268.0 -77300.0 -0.57 559907.0 -102000.0 -0.78 -0.9489 -0.9878 1965219 CMLD1_000185 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccccc2)[C@]3(C)C[C@H]3C4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I18 compound treatment 652432.0 -35100.0 -0.26 600920.0 -61200.0 -0.47 -0.5105 -0.9608 1965220 CMLD1_000186 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(OC(F)(F)F)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I19 compound treatment 676792.0 -10800.0 -0.08 615674.0 -46500.0 -0.35 -0.3053 -0.8439 1965221 CMLD1_000187 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccs2)c3ccccc3C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I20 compound treatment 689347.0 1800.0 0.01 680147.0 18000.0 0.14 0.106 0.7717 1965222 CMLD1_000188 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I21 compound treatment 685690.0 -1850.0 -0.01 654321.0 -7840.0 -0.06 -0.0517 -0.8465 1965223 CMLD1_000189 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CC6CC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I22 mock treatment 782239.0 94700.0 0.69 714721.0 52600.0 0.4 0.772 0.9658 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I23 mock treatment 749672.0 62100.0 0.45 656391.0 -5770.0 -0.04 0.2903 0.636 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 I24 mock treatment 637990.0 -49600.0 -0.36 647968.0 -14200.0 -0.11 -0.3325 -0.8794 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J01 compound treatment 581823.0 -106000.0 -0.77 674805.0 12600.0 0.1 -0.4788 -0.6145 1965224 CMLD1_000190 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J02 compound treatment 644145.0 -43400.0 -0.32 611128.0 -51000.0 -0.39 -0.4985 -0.9951 1965225 CMLD1_000191 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)o7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J03 compound treatment 645487.0 -42100.0 -0.31 609759.0 -52400.0 -0.4 -0.499 -0.9919 1965226 CMLD1_000192 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(nc7)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J04 compound treatment 452355.0 -235000.0 -1.72 524233.0 -138000.0 -1.05 -1.9571 -0.9718 1965227 CMLD1_000193 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@](CO)(CC32CC3)c4ccccc4)P(=O)(c5ccccc5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J05 compound treatment 682171.0 -5370.0 -0.04 621186.0 -41000.0 -0.31 -0.2479 -0.7901 1965228 CMLD1_000194 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J06 compound treatment 554186.0 -133000.0 -0.98 576300.0 -85900.0 -0.65 -1.1508 -0.9809 1965229 CMLD1_000195 OC1(CN(CC2(CC2)C1)P(=O)(c3ccccc3)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J07 compound treatment 596081.0 -91500.0 -0.67 605080.0 -57100.0 -0.43 -0.7796 -0.978 1965230 CMLD1_000196 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J08 compound treatment 600109.0 -87400.0 -0.64 740393.0 78200.0 0.59 -0.0319 -0.0365 1965231 CMLD1_000197 CCCC1(NCC2=C(C(C)C)C(=O)C(C)C2=C1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J09 compound treatment 632157.0 -55400.0 -0.41 653848.0 -8310.0 -0.06 -0.3311 -0.8076 1965232 CMLD1_000198 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J10 compound treatment 552275.0 -135000.0 -0.99 525827.0 -136000.0 -1.04 -1.4318 -0.9997 1965233 CMLD1_000199 COC(=O)C1(CC(C)C)NCC2=C(C(C)C)C(=O)C(C)C2=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J11 compound treatment 570517.0 -117000.0 -0.86 722653.0 60500.0 0.46 -0.2802 -0.2885 1965234 CMLD1_000200 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J12 compound treatment 717222.0 29700.0 0.22 652388.0 -9770.0 -0.07 0.101 0.4402 1965235 CMLD1_000201 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cccc(Cl)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J13 compound treatment 732216.0 44700.0 0.33 706739.0 44600.0 0.34 0.4705 0.9998 1965236 CMLD1_000202 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(cc7)S(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J14 compound treatment 637868.0 -49700.0 -0.36 752439.0 90300.0 0.69 0.2281 0.2939 1965237 CMLD1_000203 CC[C@@H]1C(COC(=O)C)C(COC(=O)C)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J15 compound treatment 633906.0 -53600.0 -0.39 712593.0 50400.0 0.38 -0.0065 -0.0118 1965238 CMLD1_000204 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J16 compound treatment 692861.0 5320.0 0.04 713303.0 51100.0 0.39 0.3022 0.774 1965239 CMLD1_000205 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J17 compound treatment 682455.0 -5090.0 -0.04 661451.0 -707.0 -0.01 -0.0301 -0.8009 1965240 CMLD1_000206 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J18 compound treatment 740320.0 52800.0 0.39 675844.0 13700.0 0.1 0.3464 0.8667 1965241 CMLD1_000207 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J19 compound treatment 714178.0 26600.0 0.19 688242.0 26100.0 0.2 0.2778 1.0 1965242 CMLD1_000208 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccccn7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J20 compound treatment 595721.0 -91800.0 -0.67 674669.0 12500.0 0.1 -0.4076 -0.601 1965243 CMLD1_000209 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J21 compound treatment 850210.0 163000.0 1.19 573385.0 -88800.0 -0.67 0.3643 0.2664 1965244 CMLD1_000210 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J22 mock treatment 722051.0 34500.0 0.25 763755.0 102000.0 0.77 0.7242 0.8918 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J23 mock treatment 668919.0 -18600.0 -0.14 662143.0 -15.4 0.0 -0.0964 -0.7077 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 J24 mock treatment 673711.0 -13800.0 -0.1 600381.0 -61800.0 -0.47 -0.4034 -0.8402 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K01 compound treatment 677831.0 -9710.0 -0.07 603621.0 -58500.0 -0.44 -0.3647 -0.8098 1965245 CMLD1_000211 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccc(cc3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K02 compound treatment 697893.0 10300.0 0.08 688362.0 26200.0 0.2 0.1943 0.9122 1965246 CMLD1_000212 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K03 compound treatment 574767.0 -113000.0 -0.82 656333.0 -5830.0 -0.04 -0.6145 -0.744 1965247 CMLD1_000213 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccc2cccnc12)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K04 compound treatment 704748.0 17200.0 0.13 747099.0 84900.0 0.65 0.5452 0.8294 1965248 CMLD1_000214 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K05 compound treatment 614947.0 -72600.0 -0.53 644495.0 -17700.0 -0.13 -0.4703 -0.8588 1965249 CMLD1_000215 CCCC=C(CCC)[C@@H](NC(=O)C(C)(C)C)c1ccc(cc1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K06 compound treatment 616316.0 -71200.0 -0.52 763907.0 102000.0 0.77 0.1782 0.1912 1965250 CMLD1_000216 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)c(F)c(F)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K07 compound treatment 559119.0 -128000.0 -0.94 651654.0 -10500.0 -0.08 -0.7205 -0.7644 1965251 CMLD1_000217 CCCCC=C[C@@H](NC(=O)c1ccc(cc1)C(=O)OC)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K08 compound treatment 645200.0 -42300.0 -0.31 739538.0 77400.0 0.59 0.1967 0.296 1965252 CMLD1_000218 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K09 compound treatment 636231.0 -51300.0 -0.38 616148.0 -46000.0 -0.35 -0.5125 -0.9994 1965253 CMLD1_000219 CCCC=C(CCC)[C@@H](NC(=O)Cc1ccccc1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K10 compound treatment 619722.0 -67800.0 -0.5 643341.0 -18800.0 -0.14 -0.4518 -0.8753 1965254 CMLD1_000220 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K11 compound treatment 585722.0 -102000.0 -0.74 621248.0 -40900.0 -0.31 -0.7463 -0.9249 1965255 CMLD1_000221 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K12 compound treatment 565924.0 -122000.0 -0.89 660922.0 -1240.0 -0.01 -0.6356 -0.7145 1965256 CMLD1_000222 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(OC)cc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K13 compound treatment 459938.0 -228000.0 -1.66 467301.0 -195000.0 -1.48 -2.2237 -0.9983 1965257 CMLD1_000223 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccco2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K14 compound treatment 679583.0 -7960.0 -0.06 699142.0 37000.0 0.28 0.1575 0.5489 1965258 CMLD1_000224 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(nc6)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K15 compound treatment 590887.0 -96700.0 -0.71 590336.0 -71800.0 -0.55 -0.8856 -0.9918 1965259 CMLD1_000225 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K16 compound treatment 714090.0 26500.0 0.19 728941.0 66800.0 0.51 0.496 0.9131 1965260 CMLD1_000226 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K17 compound treatment 416566.0 -271000.0 -1.98 471490.0 -191000.0 -1.45 -2.4255 -0.9881 1965261 CMLD1_000227 COC(=O)c1ccc(cc1)[C@H](NC(=O)c2ccco2)[C@]3(C)C[C@H]3C4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K18 compound treatment 672577.0 -15000.0 -0.11 706702.0 44500.0 0.34 0.1619 0.4552 1965262 CMLD1_000228 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(F)cc8COCOc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K19 compound treatment 600427.0 -87100.0 -0.64 584529.0 -77600.0 -0.59 -0.8675 -0.9993 1965263 CMLD1_000229 CCCC[C@@H]1C[C@H]1[C@@H](NP(=O)(c2ccccc2)c3ccccc3)c4ccc(Cl)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K20 compound treatment 724273.0 36700.0 0.27 807329.0 145000.0 1.1 0.9697 0.8544 1965264 CMLD1_000230 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K21 compound treatment 732350.0 44800.0 0.33 735298.0 73100.0 0.56 0.6246 0.9683 1965265 CMLD1_000231 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K22 mock treatment 703333.0 15800.0 0.12 698301.0 36100.0 0.27 0.2758 0.9259 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K23 mock treatment 658125.0 -29400.0 -0.22 613299.0 -48900.0 -0.37 -0.4146 -0.9664 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 K24 mock treatment 605065.0 -82500.0 -0.6 636490.0 -25700.0 -0.19 -0.5644 -0.8903 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L01 compound treatment 704365.0 16800.0 0.12 551129.0 -111000.0 -0.84 -0.5094 -0.5977 1965266 CMLD1_000232 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CNCC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L02 compound treatment 627108.0 -60400.0 -0.44 612582.0 -49600.0 -0.38 -0.5788 -0.9968 1965267 CMLD1_000233 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L03 compound treatment 652749.0 -34800.0 -0.25 693476.0 31300.0 0.24 -0.0117 -0.0336 1965268 CMLD1_000234 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L04 compound treatment 618119.0 -69400.0 -0.51 581431.0 -80700.0 -0.61 -0.7927 -0.9956 1965269 CMLD1_000235 CCCC[C@H]1C[C@@H]1[C@@H]2N([C@@H](CC32CC3)c4cccc(OC)c4)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L05 compound treatment 624185.0 -63400.0 -0.46 810878.0 149000.0 1.13 0.4712 0.3859 1965270 CMLD1_000236 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7cc8ccccc8[nH]7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L06 compound treatment 532575.0 -155000.0 -1.13 558830.0 -103000.0 -0.78 -1.3564 -0.9839 1965271 CMLD1_000237 C=C(CC1(CNP(=O)(c2ccccc2)c3ccccc3)CC1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L07 compound treatment 637073.0 -50500.0 -0.37 675627.0 13500.0 0.1 -0.1886 -0.4925 1965272 CMLD1_000238 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L08 compound treatment 590374.0 -97200.0 -0.71 662599.0 441.0 0.0 -0.5001 -0.7038 1965273 CMLD1_000239 CCCC1(NCC2=C(C(=O)C(C)C2=C1)c3ccccc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L09 compound treatment 649311.0 -38200.0 -0.28 758696.0 96500.0 0.73 0.3209 0.4088 1965274 CMLD1_000240 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(O)c(OC)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L10 compound treatment 653218.0 -34300.0 -0.25 707509.0 45400.0 0.34 0.0661 0.1551 1965275 CMLD1_000241 COC(=O)C1(CC(C)C)NCC2=C(C(=O)C(C)C2=C1)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L11 compound treatment 604234.0 -83300.0 -0.61 637830.0 -24300.0 -0.18 -0.5615 -0.8819 1965276 CMLD1_000242 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L12 compound treatment 638259.0 -49300.0 -0.36 665508.0 3350.0 0.03 -0.2369 -0.6556 1965277 CMLD1_000243 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5cc(F)cc(F)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L13 compound treatment 580636.0 -107000.0 -0.78 534013.0 -128000.0 -0.97 -1.2412 -0.9941 1965278 CMLD1_000244 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L14 compound treatment 690596.0 3050.0 0.02 748136.0 86000.0 0.65 0.4776 0.7308 1965279 CMLD1_000245 CC[C@@H]1C2COC(=O)OCC2C3CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@]6(C)[C@H]4C3=C1CN6C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L15 compound treatment 649874.0 -37700.0 -0.28 711616.0 49500.0 0.38 0.0709 0.1521 1965280 CMLD1_000246 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L16 compound treatment 652704.0 -34800.0 -0.25 706437.0 44300.0 0.34 0.0577 0.1367 1965281 CMLD1_000247 CC(=C1[C@H]2C(=C(C1=O)c3ccccc3)CN4C(=O)N(CCc5ccccc5)C(=O)[C@]24Cc6ccccc6)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L17 compound treatment 589458.0 -98100.0 -0.72 550489.0 -112000.0 -0.85 -1.1071 -0.9965 1965282 CMLD1_000248 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSC(=N)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L18 compound treatment 573044.0 -115000.0 -0.84 573549.0 -88600.0 -0.67 -1.0681 -0.9941 1965079 CMLD1_000249 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5C[C@H](O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L19 compound treatment 660837.0 -26700.0 -0.2 719866.0 57700.0 0.44 0.1719 0.3581 1965283 CMLD1_000250 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8cc(F)ccc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L20 compound treatment 693474.0 5930.0 0.04 681972.0 19800.0 0.15 0.1371 0.8752 1965284 CMLD1_000251 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L21 compound treatment 641874.0 -45700.0 -0.33 719166.0 57000.0 0.43 0.0701 0.1281 1965285 CMLD1_000252 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L22 mock treatment 702581.0 15000.0 0.11 707635.0 45500.0 0.35 0.322 0.8883 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L23 mock treatment 692102.0 4560.0 0.03 632363.0 -29800.0 -0.23 -0.1365 -0.5966 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 L24 mock treatment 638624.0 -48900.0 -0.36 738980.0 76800.0 0.58 0.1597 0.2333 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M01 compound treatment 677814.0 -9730.0 -0.07 648322.0 -13800.0 -0.11 -0.1246 -0.982 1965286 CMLD1_000253 CCCC=C(CCC)[C@@H](NC(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M02 compound treatment 620497.0 -67000.0 -0.49 695716.0 33600.0 0.25 -0.1665 -0.3012 1965287 CMLD1_000254 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N4CCCC4)C(=O)C=C3CN1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M03 compound treatment 617506.0 -70000.0 -0.51 655824.0 -6330.0 -0.05 -0.3962 -0.7701 1965288 CMLD1_000255 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1ccc(cc1)C(F)(F)F)c2ccc(cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M04 compound treatment 606953.0 -80600.0 -0.59 707013.0 44900.0 0.34 -0.1758 -0.2582 1965289 CMLD1_000256 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(C)onc7c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M05 compound treatment 634379.0 -53200.0 -0.39 682436.0 20300.0 0.15 -0.166 -0.3969 1965290 CMLD1_000257 CCCC=C(CCC)[C@@H](NC(=O)c1ccc(cc1)c2ccccc2)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M06 compound treatment 792313.0 105000.0 0.77 844144.0 182000.0 1.38 1.5194 0.9612 1965090 CMLD1_000258 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccc(cc2)c3ccccc3)c4cccc(Cl)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M07 compound treatment 646657.0 -40900.0 -0.3 750621.0 88500.0 0.67 0.2638 0.3586 1965291 CMLD1_000259 CCCCC=C[C@@H](NC(=O)c1ccco1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M08 compound treatment 737075.0 49500.0 0.36 651872.0 -10300.0 -0.08 0.2009 0.5421 1965292 CMLD1_000260 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M09 compound treatment 659831.0 -27700.0 -0.2 696702.0 34500.0 0.26 0.0422 0.1274 1965293 CMLD1_000261 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)OCc2ccccc2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M10 compound treatment 651568.0 -36000.0 -0.26 671403.0 9240.0 0.07 -0.1364 -0.5008 1965294 CMLD1_000262 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCCNc6ccc(cc6Cl)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M11 compound treatment 650468.0 -37100.0 -0.27 676637.0 14500.0 0.11 -0.114 -0.3894 1965295 CMLD1_000263 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2cccnc2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M12 compound treatment 553748.0 -134000.0 -0.98 606253.0 -55900.0 -0.42 -0.9922 -0.9302 1965296 CMLD1_000264 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(OC)c(Br)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M13 compound treatment 369817.0 -318000.0 -2.32 365541.0 -297000.0 -2.25 -3.2364 -0.9999 1965297 CMLD1_000265 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M14 compound treatment 695882.0 8340.0 0.06 722891.0 60700.0 0.46 0.3694 0.7937 1965298 CMLD1_000266 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccsc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M15 compound treatment 657088.0 -30500.0 -0.22 684604.0 22400.0 0.17 -0.0369 -0.1316 1965299 CMLD1_000267 CCCC[C@@H]1C[C@H]1[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M16 compound treatment 680441.0 -7100.0 -0.05 704890.0 42700.0 0.32 0.1928 0.5865 1965300 CMLD1_000268 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6ccc(O)c(O)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M17 compound treatment 691404.0 3860.0 0.03 679272.0 17100.0 0.13 0.1119 0.841 1965301 CMLD1_000269 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NS(=O)(=O)c2cccc3cccnc23)c4ccc(Cl)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M18 compound treatment 702965.0 15400.0 0.11 664535.0 2380.0 0.02 0.0925 0.81 1965302 CMLD1_000270 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M19 compound treatment 693311.0 5770.0 0.04 657527.0 -4630.0 -0.04 0.0049 0.09 1965303 CMLD1_000271 CCCC=C(CCC)[C@@H](NC(=O)Oc1ccc(F)cc1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M20 compound treatment 751465.0 63900.0 0.47 792320.0 130000.0 0.99 1.0297 0.9415 1965304 CMLD1_000272 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)c(F)c6F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M21 mock treatment 787042.0 99500.0 0.73 645708.0 -16500.0 -0.12 0.4261 0.5772 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M22 mock treatment 732721.0 45200.0 0.33 620389.0 -41800.0 -0.32 0.0092 0.0202 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M23 mock treatment 682369.0 -5180.0 -0.04 674973.0 12800.0 0.1 0.0421 0.4028 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 M24 mock treatment 697898.0 10400.0 0.08 683473.0 21300.0 0.16 0.168 0.9401 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N01 compound treatment 640175.0 -47400.0 -0.35 660434.0 -1720.0 -0.01 -0.2542 -0.7333 1965305 CMLD1_000273 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCN6CNCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N02 compound treatment 611143.0 -76400.0 -0.56 570988.0 -91200.0 -0.69 -0.8848 -0.9943 1965306 CMLD1_000274 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N03 compound treatment 740501.0 53000.0 0.39 762032.0 99900.0 0.76 0.8103 0.9513 1965307 CMLD1_000275 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(C)o6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N04 compound treatment 725594.0 38000.0 0.28 705235.0 43100.0 0.33 0.4282 0.9967 1965308 CMLD1_000276 COC(=O)c1ccc(C#CC(NP(=O)(c2ccccc2)c3ccccc3)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N05 compound treatment 620065.0 -67500.0 -0.49 854081.0 192000.0 1.46 0.682 0.4431 1965309 CMLD1_000277 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(C)c(F)c7F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N06 compound treatment 714719.0 27200.0 0.2 761784.0 99600.0 0.76 0.6757 0.8635 1965310 CMLD1_000278 O=P(NCC1(CC2(CO2)c3ccccc3)CC1)(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N07 compound treatment 715011.0 27500.0 0.2 683148.0 21000.0 0.16 0.2548 0.9935 1965311 CMLD1_000279 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5C[C@H](O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N08 compound treatment 727127.0 39600.0 0.29 739490.0 77300.0 0.59 0.6201 0.9468 1965312 CMLD1_000280 CCCCCC1=C2CNC(CCC)(C=C2C(C)C1=O)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N09 compound treatment 744648.0 57100.0 0.42 738796.0 76600.0 0.58 0.707 0.9867 1965313 CMLD1_000281 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCN7CCOCC7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N10 compound treatment 731432.0 43900.0 0.32 706985.0 44800.0 0.34 0.4677 0.9996 1965314 CMLD1_000282 CCCCCC1=C2CNC(CC(C)C)(C=C2C(C)C1=O)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N11 compound treatment 797366.0 110000.0 0.8 714939.0 52800.0 0.4 0.8514 0.9485 1965315 CMLD1_000283 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cc(C)n(C)n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N12 compound treatment 800165.0 113000.0 0.82 796076.0 134000.0 1.02 1.3017 0.9945 1965316 CMLD1_000284 COC1OC[C@]2(C)[C@@H]3[C@H]1CCC4C(CO)C(CO)[C@@H](C)C(=C43)CN2C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N13 compound treatment 697533.0 9990.0 0.07 748042.0 85900.0 0.65 0.513 0.7814 1965317 CMLD1_000285 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccccc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N14 compound treatment 623036.0 -64500.0 -0.47 781710.0 120000.0 0.91 0.3086 0.3016 1965318 CMLD1_000286 CC[C@@H]1C(COC)C(COC)C2CC[C@H]3C(OCc4ccc(F)cc4C(F)(F)F)OC[C@]5(C)[C@H]3C2=C1CN5C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N15 compound treatment 780418.0 92900.0 0.68 795379.0 133000.0 1.01 1.1959 0.9812 1965319 CMLD1_000287 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N16 compound treatment 807709.0 120000.0 0.88 647027.0 -15100.0 -0.11 0.5401 0.6094 1965320 CMLD1_000288 CC1(C)C(=O)C(=C2CN3C(=O)N(CCc4ccccc4)C(=O)C3(Cc5ccccc5)C=C21)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N17 compound treatment 733300.0 45800.0 0.33 745205.0 83000.0 0.63 0.6827 0.956 1965321 CMLD1_000289 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N18 compound treatment 756430.0 68900.0 0.5 658629.0 -3530.0 -0.03 0.3373 0.6685 1965322 CMLD1_000290 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5[nH]c(cc35)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N19 compound treatment 838884.0 151000.0 1.11 665429.0 3270.0 0.02 0.8002 0.7228 1965323 CMLD1_000291 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7c[nH]c8ccc(O)cc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N20 compound treatment 715683.0 28100.0 0.21 762333.0 100000.0 0.76 0.6836 0.8672 1965324 CMLD1_000292 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N21 mock treatment 769622.0 82100.0 0.6 699447.0 37300.0 0.28 0.6247 0.9413 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N22 mock treatment 773993.0 86400.0 0.63 756171.0 94000.0 0.71 0.952 0.9982 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N23 mock treatment 681779.0 -5770.0 -0.04 699906.0 37700.0 0.29 0.173 0.5967 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 N24 mock treatment 787984.0 100000.0 0.73 734638.0 72500.0 0.55 0.9087 0.9899 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O01 compound treatment 652584.0 -35000.0 -0.26 705417.0 43300.0 0.33 0.0516 0.1239 1965325 CMLD1_000293 CCCC=C(CCC)[C@@H](NC(=O)OCC(C)C)c1ccc(cc1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O02 compound treatment 424639.0 -263000.0 -1.92 487874.0 -174000.0 -1.32 -2.2957 -0.9834 1965326 CMLD1_000294 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O03 compound treatment 727249.0 39700.0 0.29 728018.0 65900.0 0.5 0.5591 0.9665 1965327 CMLD1_000295 CCCC=C(CCC)[C@@H](NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O04 compound treatment 716002.0 28500.0 0.21 776752.0 115000.0 0.87 0.7627 0.8521 1965268 CMLD1_000296 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(O)c(OC)c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O05 compound treatment 147683.0 -540000.0 -3.95 184497.0 -478000.0 -3.63 -5.3576 -0.9991 1965328 CMLD1_000297 CCCC=C(CCC)[C@@H](NS(=O)(=O)c1cccs1)c2ccc(cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O06 compound treatment 819587.0 132000.0 0.97 793009.0 131000.0 0.99 1.3857 0.9999 1965329 CMLD1_000298 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7cccc8ccccc78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O07 compound treatment 460833.0 -227000.0 -1.66 523402.0 -139000.0 -1.05 -1.9177 -0.9761 1965330 CMLD1_000299 CCCCC=C[C@@H](NC(=O)c1cccs1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O08 compound treatment 682701.0 -4840.0 -0.04 650114.0 -12000.0 -0.09 -0.0897 -0.9147 1965331 CMLD1_000300 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O09 compound treatment 568309.0 -119000.0 -0.87 529751.0 -132000.0 -1.01 -1.3278 -0.9975 1965332 CMLD1_000301 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O10 compound treatment 591113.0 -96400.0 -0.71 583176.0 -79000.0 -0.6 -0.9229 -0.9968 1965333 CMLD1_000302 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C[C@H]3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O11 compound treatment 684850.0 -2690.0 -0.02 750352.0 88200.0 0.67 0.4598 0.686 1965334 CMLD1_000303 CCCC=C(CCC)[C@@H](NC(=O)c1ccccc1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O12 compound treatment 411622.0 -276000.0 -2.02 461996.0 -200000.0 -1.52 -2.5021 -0.9903 1965335 CMLD1_000304 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCc7ccc(OC)c(Br)c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O13 compound treatment 682118.0 -5430.0 -0.04 607335.0 -54800.0 -0.42 -0.3226 -0.771 1965336 CMLD1_000305 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)Cc2ccccc2)c3ccc(cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O14 compound treatment 644017.0 -43500.0 -0.32 681896.0 19700.0 0.15 -0.1191 -0.3384 1965337 CMLD1_000306 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccsc7Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O15 compound treatment 620677.0 -66900.0 -0.49 547964.0 -114000.0 -0.87 -0.9592 -0.9632 1965338 CMLD1_000307 CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c2ccccc2)c3ccc(cc3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O16 compound treatment 650820.0 -36700.0 -0.27 606338.0 -55800.0 -0.42 -0.4898 -0.9757 1965339 CMLD1_000308 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O17 compound treatment 607398.0 -80100.0 -0.59 542609.0 -120000.0 -0.91 -1.0566 -0.9776 1965340 CMLD1_000309 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2ccco2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O18 compound treatment 694620.0 7080.0 0.05 766013.0 104000.0 0.79 0.5945 0.7519 1965341 CMLD1_000310 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCSCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O19 compound treatment 601722.0 -85800.0 -0.63 578792.0 -83400.0 -0.63 -0.8916 -1.0 1965342 CMLD1_000311 CCC[C@@H]1C[C@@]1(CCC)[C@@H](NC(=O)c2cccs2)c3ccc(Cl)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O20 compound treatment 686689.0 -856.0 -0.01 683359.0 21200.0 0.16 0.1095 0.6791 1965343 CMLD1_000312 COC(=O)[C@@]1(Cc2ccccc2)[C@H]3[C@H](CC(=O)C(=O)N(C)C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O21 mock treatment 693242.0 5700.0 0.04 607842.0 -54300.0 -0.41 -0.2623 -0.6325 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O22 mock treatment 658160.0 -29400.0 -0.21 659113.0 -3050.0 -0.02 -0.1683 -0.7787 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O23 mock treatment 795542.0 108000.0 0.79 702917.0 40800.0 0.31 0.7774 0.9164 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 O24 mock treatment 664564.0 -23000.0 -0.17 680821.0 18700.0 0.14 -0.0186 -0.0845 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P01 compound treatment 729688.0 42100.0 0.31 831221.0 169000.0 1.28 1.1261 0.8526 1965344 CMLD1_000313 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6ccc(cc6)S(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P02 compound treatment 670606.0 -16900.0 -0.12 767029.0 105000.0 0.8 0.4757 0.5901 1965345 CMLD1_000314 COC(=O)Cn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(F)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P03 compound treatment 757855.0 70300.0 0.51 821418.0 159000.0 1.21 1.2191 0.9273 1965346 CMLD1_000315 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCc6c[nH]c7ccc(O)cc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P04 compound treatment 826254.0 139000.0 1.01 804467.0 142000.0 1.08 1.4817 0.9995 1965347 CMLD1_000316 COC(=O)c1ccc(cc1)C23CC3(C2)C(NP(=O)(c4ccccc4)c5ccccc5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P05 compound treatment 716191.0 28600.0 0.21 807850.0 146000.0 1.11 0.9308 0.8263 1965348 CMLD1_000317 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7ccc(Cl)c(c7)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P06 compound treatment 706270.0 18700.0 0.14 815718.0 154000.0 1.17 0.9217 0.7847 1965349 CMLD1_000318 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(F)cc5C(F)(F)F)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P07 compound treatment 621915.0 -65600.0 -0.48 795127.0 133000.0 1.01 0.3749 0.3352 1965350 CMLD1_000319 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5Cc7c(O)c(C)cnc7CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P08 compound treatment 691222.0 3680.0 0.03 688131.0 26000.0 0.2 0.1585 0.7961 1965351 CMLD1_000320 COC(=O)C1(Cc2ccccc2)NCC3=C(C)C(=O)C(C)C3=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P09 compound treatment 643395.0 -44100.0 -0.32 768907.0 107000.0 0.81 0.3451 0.3954 1965352 CMLD1_000321 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N6CCCC6)n5CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P10 compound treatment 779942.0 92400.0 0.68 779484.0 117000.0 0.89 1.108 0.9907 1965353 CMLD1_000322 CCCc1cc2C3C(CN(C(=O)c4ccccc4)C3(C)C(=O)OC)C(C)c2n1Cc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P11 compound treatment 766916.0 79400.0 0.58 837240.0 175000.0 1.33 1.3509 0.9309 1965354 CMLD1_000323 COCCn1c(cc2[C@H]3[C@H](CN(C(=O)c4ccccc4)[C@@]3(Cc5ccc(OC)cc5)C(=O)OC)Cc21)C(=O)N6CCCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P12 compound treatment 748515.0 61000.0 0.45 725581.0 63400.0 0.48 0.656 0.9993 1965355 CMLD1_000324 CC[C@@H]1C(CO)C(CO)C2CC[C@H]3C(OC)OC[C@]4(C)[C@H]3C2=C1CN4C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P13 compound treatment 746865.0 59300.0 0.43 823460.0 161000.0 1.23 1.1732 0.9026 1965356 CMLD1_000325 COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6c(O)c(C)cnc6OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P14 compound treatment 751667.0 64100.0 0.47 771602.0 109000.0 0.83 0.9195 0.9633 1965357 CMLD1_000326 COCC1[C@@H](C)C2=C3C(CC[C@H]4C(OCc5ccc(OC)cc5)OC[C@](C)([C@H]43)N(C2)C(=O)OC(C)(C)C)C1COC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P15 compound treatment 585881.0 -102000.0 -0.74 542400.0 -120000.0 -0.91 -1.169 -0.995 1965358 CMLD1_000327 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCn6cc(nc6C)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P16 compound treatment 739656.0 52100.0 0.38 725057.0 62900.0 0.48 0.6074 0.9937 1965359 CMLD1_000328 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6cc(F)cc7COCOc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P17 compound treatment 143714.0 -544000.0 -3.98 139725.0 -522000.0 -3.97 -5.6186 -1.0 1965360 CMLD1_000329 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]3C(=C)C(=O)C=C3CN1C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P18 compound treatment 848172.0 161000.0 1.17 566668.0 -95500.0 -0.73 0.3177 0.2301 1965361 CMLD1_000330 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P19 compound treatment 722983.0 35400.0 0.26 787841.0 126000.0 0.95 0.8584 0.8676 1965362 CMLD1_000331 COC(=O)[C@@]1(Cc2ccccc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5Cc6nc7ccccc7[nH]6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P20 compound treatment 721424.0 33900.0 0.25 652125.0 -10000.0 -0.08 0.1213 0.4679 1965363 CMLD1_000332 COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@@H]3[C@H](CN1C(=O)c4ccccc4)Cc5c3cc(C(=O)N(C)C)n5CCF 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P21 mock treatment 775692.0 88100.0 0.64 722176.0 60000.0 0.46 0.7782 0.9856 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P22 mock treatment 712503.0 25000.0 0.18 721564.0 59400.0 0.45 0.4482 0.9206 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P23 mock treatment 758501.0 71000.0 0.52 708047.0 45900.0 0.35 0.6134 0.9813 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1462 P24 mock treatment 709747.0 22200.0 0.16 680687.0 18500.0 0.14 0.2143 0.9975 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A01 compound treatment 637245.0 4080.0 0.03 756023.0 127000.0 0.96 0.7011 0.7287 2065621 ICCB6_000001 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A02 compound treatment 467352.0 -166000.0 -1.21 634633.0 5200.0 0.04 -0.8295 -0.6837 2065622 ICCB6_000002 OCCCCCCCCCc1ccc(C=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A03 compound treatment 529798.0 -103000.0 -0.76 563192.0 -66200.0 -0.5 -0.8903 -0.9804 2065623 ICCB6_000003 CC1(C)OC(=O)C=C(CC(O)c2ccccc2)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A04 compound treatment 450830.0 -182000.0 -1.33 545670.0 -83800.0 -0.64 -1.3928 -0.9427 2065624 ICCB6_000004 CO[C@H]1O[C@H](CO)[C@@H](OCc2ccccc2)[C@H](OCc3ccccc3)[C@@H]1OCCCc4ccc(C=O)o4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A05 compound treatment 492508.0 -141000.0 -1.03 585108.0 -44300.0 -0.34 -0.9655 -0.892 2065625 ICCB6_000005 Clc1ccccc1C(CC(=O)c2ccccc2)C(=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A06 compound treatment 470273.0 -163000.0 -1.19 544055.0 -85400.0 -0.65 -1.301 -0.9591 2065626 ICCB6_000006 OCCCCCCCCCCc1ccc(C=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A07 compound treatment 567427.0 -65700.0 -0.48 666202.0 36800.0 0.28 -0.1424 -0.2561 2065627 ICCB6_000007 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A08 compound treatment 458108.0 -175000.0 -1.28 603397.0 -26000.0 -0.2 -1.0451 -0.8068 2065628 ICCB6_000008 OC[C@H](COCCCc1ccc(C=O)o1)OCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A09 compound treatment 536009.0 -97200.0 -0.71 588198.0 -41200.0 -0.31 -0.7239 -0.9323 2065629 ICCB6_000009 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A10 compound treatment 507066.0 -126000.0 -0.92 616951.0 -12500.0 -0.09 -0.7191 -0.7757 2065630 ICCB6_000010 OCCOCCCc1ccc(C=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A11 compound treatment 575560.0 -57600.0 -0.42 771483.0 142000.0 1.08 0.4652 0.4016 2065631 ICCB6_000011 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A12 compound treatment 584722.0 -48400.0 -0.35 706259.0 76800.0 0.58 0.1622 0.2376 2065632 ICCB6_000012 OCc1ccc(CCc2ccc(C=O)o2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A13 compound treatment 521678.0 -111000.0 -0.82 613874.0 -15600.0 -0.12 -0.6601 -0.8012 2065633 ICCB6_000013 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A14 compound treatment 514972.0 -118000.0 -0.86 562406.0 -67000.0 -0.51 -0.9712 -0.9682 2065634 ICCB6_000014 OCCOCCOCCCc1ccc(C=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A15 compound treatment 545426.0 -87700.0 -0.64 610714.0 -18700.0 -0.14 -0.5543 -0.8433 ICCB6_000015 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A16 compound treatment 513434.0 -120000.0 -0.88 645952.0 16500.0 0.13 -0.5304 -0.5996 2065635 ICCB6_000016 OCC1CC2CCN1CC2CCc3ccc(C=O)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A17 compound treatment 570204.0 -63000.0 -0.46 646917.0 17500.0 0.13 -0.2317 -0.4834 1952805 ICCB6_000017 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A18 compound treatment 576449.0 -56700.0 -0.41 649314.0 19900.0 0.15 -0.1865 -0.4225 2065636 ICCB6_000018 OCCCCNC(=O)OCCCc1ccc(C=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A19 compound treatment 517639.0 -116000.0 -0.84 512930.0 -117000.0 -0.89 -1.2232 -0.9997 1952839 ICCB6_000019 Oc1ccccc1C#CC#Cc2ccccc2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A20 compound treatment 557767.0 -75400.0 -0.55 537322.0 -92100.0 -0.7 -0.8847 -0.993 2065637 ICCB6_000020 OCCCCc1ccc(C=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A21 compound treatment 367059.0 -266000.0 -1.95 415115.0 -214000.0 -1.63 -2.5273 -0.9961 1952635 ICCB6_000021 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A22 compound treatment 410023.0 -223000.0 -1.63 505984.0 -123000.0 -0.94 -1.817 -0.9654 2065638 ICCB6_000022 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A23 mock treatment 550323.0 -82800.0 -0.61 514604.0 -115000.0 -0.87 -1.0452 -0.9841 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 A24 mock treatment 516595.0 -117000.0 -0.85 525746.0 -104000.0 -0.79 -1.1598 -0.9992 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B01 compound treatment 597253.0 -35900.0 -0.26 644637.0 15200.0 0.12 -0.104 -0.3626 2065621 ICCB6_000023 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B02 compound treatment 551228.0 -81900.0 -0.6 605334.0 -24100.0 -0.18 -0.5532 -0.8828 2065639 ICCB6_000024 OB1OC(COCc2ccccc2)CC=C1C(=C)CCCc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B03 compound treatment 514737.0 -118000.0 -0.87 542475.0 -87000.0 -0.66 -1.0795 -0.9911 2065640 ICCB6_000025 CC1(C)OC(=O)C=C(CC(O)C2CCCCC2)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B04 compound treatment 529866.0 -103000.0 -0.76 562393.0 -67000.0 -0.51 -0.8943 -0.9816 2065641 ICCB6_000026 CC(C)C(=C)C1=CCC(COCc2ccccc2)OB1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B05 compound treatment 449148.0 -184000.0 -1.35 499728.0 -130000.0 -0.99 -1.6483 -0.9883 2065642 ICCB6_000027 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B06 compound treatment 533597.0 -99600.0 -0.73 582579.0 -46900.0 -0.36 -0.7666 -0.9458 2065643 ICCB6_000028 CCCC(=C)C1=CCC(COCc2ccccc2)OB1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B07 compound treatment 571116.0 -62000.0 -0.45 589962.0 -39500.0 -0.3 -0.5329 -0.9798 2065644 ICCB6_000029 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B08 compound treatment 193834.0 -439000.0 -3.21 223580.0 -406000.0 -3.08 -4.452 -0.9998 2065645 ICCB6_000030 O[C@@H]([C@H](Oc1ccccc1)C=C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B09 compound treatment 573609.0 -59600.0 -0.44 661617.0 32200.0 0.24 -0.1351 -0.2704 2065646 ICCB6_000031 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B10 compound treatment 506158.0 -127000.0 -0.93 610115.0 -19300.0 -0.15 -0.7605 -0.8088 2065647 ICCB6_000032 O[C@H](COCc1ccccc1)[C@H](Oc2ccccc2)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B11 compound treatment 625184.0 -7980.0 -0.06 654868.0 25400.0 0.19 0.0954 0.4724 2065648 ICCB6_000033 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B12 compound treatment 518280.0 -115000.0 -0.84 563611.0 -65800.0 -0.5 -0.9477 -0.9693 2065649 ICCB6_000034 CC(C)C(=C)C(=O)CCC(COCc1ccccc1)OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B13 compound treatment 565379.0 -67800.0 -0.5 611877.0 -17600.0 -0.13 -0.4448 -0.8665 2065650 ICCB6_000035 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B14 compound treatment 404038.0 -229000.0 -1.68 421577.0 -208000.0 -1.58 -2.3014 -0.9996 2065651 ICCB6_000036 CCCC(=C=CC[C@@H](OC(=O)Nc1ccc(Br)cc1)c2ccccc2)CCOC(=O)Nc3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B15 compound treatment 557988.0 -75200.0 -0.55 647109.0 17700.0 0.13 -0.2938 -0.5191 1952458 ICCB6_000037 Fc1ccc(cc1Br)[C@@H]2C3=C(C[C@@H]4C2=CCn5n4c(=O)n(c6ccccc6)c5=O)C(=O)OC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B16 compound treatment 572943.0 -60200.0 -0.44 592538.0 -36900.0 -0.28 -0.5096 -0.9762 2065652 ICCB6_000038 CC(C)C(=C=CC[C@H](COCc1ccccc1)OC(=O)c2ccc(Br)cc2)CCOC(=O)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B17 compound treatment 604515.0 -28700.0 -0.21 625503.0 -3930.0 -0.03 -0.1693 -0.7997 1952808 ICCB6_000039 CCCCCc1cc2ccccc2o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B18 compound treatment 542950.0 -90200.0 -0.66 603550.0 -25900.0 -0.2 -0.6055 -0.8796 2065653 ICCB6_000040 CC1(C)OC[C@@H](C=C)[C@H](CCc2ccccc2)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B19 compound treatment 503676.0 -129000.0 -0.95 488592.0 -141000.0 -1.07 -1.4262 -0.9981 1952842 ICCB6_000041 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B20 compound treatment 501629.0 -132000.0 -0.96 537672.0 -91800.0 -0.7 -1.1731 -0.9875 2065654 ICCB6_000042 CCC[C@@]1(CCO[Si](c2ccccc2)(c3ccccc3)C(C)(C)C)O[C@@H](Cc4ccccc4)CC=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B21 compound treatment 369520.0 -264000.0 -1.93 455192.0 -174000.0 -1.32 -2.2993 -0.9832 1952636 ICCB6_000043 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B22 compound treatment 510555.0 -123000.0 -0.9 581316.0 -48100.0 -0.37 -0.8925 -0.9217 3056822 ICCB6_000044 CC(C)[Si](OC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)c4ccccc4C3=O)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B23 mock treatment 587487.0 -45700.0 -0.33 608643.0 -20800.0 -0.16 -0.3479 -0.9415 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 B24 mock treatment 592247.0 -40900.0 -0.3 633645.0 4210.0 0.03 -0.189 -0.6279 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C01 compound treatment 558615.0 -74600.0 -0.55 676204.0 46800.0 0.36 -0.1343 -0.2063 2065655 ICCB6_000045 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(C)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C02 compound treatment 591983.0 -41200.0 -0.3 657040.0 27600.0 0.21 -0.0647 -0.1762 2065656 ICCB6_000046 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C03 compound treatment 532614.0 -101000.0 -0.74 572472.0 -57000.0 -0.43 -0.8259 -0.968 2065657 ICCB6_000047 COC(=O)c1cn2c(c1C(=O)OC)c(=O)n(C)c3ccccc32 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C04 compound treatment 568334.0 -64800.0 -0.47 616653.0 -12800.0 -0.1 -0.4039 -0.8346 2065658 ICCB6_000048 C[C@@H]([C@H](O)c1ccc(CCCCCCO)o1)C(=O)N2[C@H](COC2=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C05 compound treatment 138256.0 -495000.0 -3.62 178768.0 -451000.0 -3.42 -4.9801 -0.9996 2065659 ICCB6_000049 C[Si](C)(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3Cl)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C06 compound treatment 559827.0 -73300.0 -0.54 644989.0 15600.0 0.12 -0.2957 -0.5384 2065660 ICCB6_000050 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C07 compound treatment 563908.0 -69300.0 -0.51 536132.0 -93300.0 -0.71 -0.8593 -0.9864 2065661 ICCB6_000051 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)CCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C08 compound treatment 587912.0 -45300.0 -0.33 679755.0 50300.0 0.38 0.0363 0.0718 2065662 ICCB6_000052 CC(C)[C@@H]1N(C(=O)[C@@H](C)[C@H](O)c2ccc(CCCCCCO)o2)C(=O)OC1(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C09 compound treatment 598640.0 -34500.0 -0.25 683980.0 54500.0 0.41 0.1145 0.2359 2065663 ICCB6_000053 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C10 compound treatment 421108.0 -212000.0 -1.55 510975.0 -118000.0 -0.9 -1.7329 -0.9665 2065664 ICCB6_000054 COC(=O)[C@H](Cc1ccccc1)NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C11 compound treatment 639572.0 6410.0 0.05 728668.0 99200.0 0.75 0.5662 0.7496 2065665 ICCB6_000055 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C12 compound treatment 413391.0 -220000.0 -1.61 501508.0 -128000.0 -0.97 -1.8237 -0.971 2065666 ICCB6_000056 CCc1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C13 compound treatment 482256.0 -151000.0 -1.1 523946.0 -105000.0 -0.8 -1.347 -0.9876 1065064 ICCB6_000057 [O-][N+](=O)c1ccc(CBr)c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C14 compound treatment 381189.0 -252000.0 -1.84 509902.0 -120000.0 -0.91 -1.9451 -0.9468 2065667 ICCB6_000058 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(Oc3ccccc3)cc2)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C15 compound treatment 666700.0 33500.0 0.25 653424.0 24000.0 0.18 0.3023 0.9893 1952482 ICCB6_000059 Fc1ccc(cc1Br)[C@H]2C3=CC[C@H]4[C@@H]([C@@H]3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C16 compound treatment 606691.0 -26500.0 -0.19 655928.0 26500.0 0.2 0.0054 0.0194 2065668 ICCB6_000060 COc1cccc(C)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C17 compound treatment 581461.0 -51700.0 -0.38 591315.0 -38100.0 -0.29 -0.4721 -0.9913 1952809 ICCB6_000061 CC(=O)Oc1ccccc1C#Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C18 compound treatment 597784.0 -35400.0 -0.26 638322.0 8890.0 0.07 -0.1352 -0.5056 2065669 ICCB6_000062 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccc(C#N)cc2)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C19 compound treatment 578244.0 -54900.0 -0.4 585166.0 -44300.0 -0.34 -0.5218 -0.9961 1952773 ICCB6_000063 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C20 compound treatment 556726.0 -76400.0 -0.56 590672.0 -38800.0 -0.29 -0.6035 -0.9552 2065670 ICCB6_000064 CCOC(=O)CNC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C21 compound treatment 240588.0 -393000.0 -2.87 241388.0 -388000.0 -2.95 -4.1145 -0.9999 1952585 ICCB6_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C22 compound treatment 512356.0 -121000.0 -0.88 532010.0 -97400.0 -0.74 -1.148 -0.9961 2065671 ICCB6_000066 OCCCCCCc1ccc(/C=C/COC(=O)Nc2ccccc2F)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C23 mock treatment 565665.0 -67500.0 -0.49 683624.0 54200.0 0.41 -0.0579 -0.0901 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 C24 mock treatment 560832.0 -72300.0 -0.53 621362.0 -8070.0 -0.06 -0.4174 -0.7838 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D01 compound treatment 584878.0 -48300.0 -0.35 649432.0 20000.0 0.15 -0.1423 -0.3701 2065672 ICCB6_000067 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D02 compound treatment 490044.0 -143000.0 -1.05 580110.0 -49300.0 -0.37 -1.005 -0.9041 2065673 ICCB6_000068 CC(C)[Si](OC[C@@H]1CC=C(C)B(O)O1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D03 compound treatment 453387.0 -180000.0 -1.31 459994.0 -169000.0 -1.29 -1.8398 -0.9999 2065674 ICCB6_000069 CCOC(=O)C1[C@H](CCc2ccccc2)O[C@H](CCc3ccccc3)CC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D04 compound treatment 435085.0 -198000.0 -1.45 445733.0 -184000.0 -1.4 -2.0111 -0.9998 2065675 ICCB6_000070 CC(C)[Si](OC[C@H]1OB(O)CC=C1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D05 compound treatment 408405.0 -225000.0 -1.64 483342.0 -146000.0 -1.11 -1.947 -0.9817 2065676 ICCB6_000071 C[Si](C)(C(N[Si](=O)(=O)c1ccccc1)c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D06 compound treatment 422844.0 -210000.0 -1.54 746239.0 117000.0 0.89 -0.4601 -0.2591 2065677 ICCB6_000072 CC(C)[Si](OCC(O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D07 compound treatment 536577.0 -96600.0 -0.71 631184.0 1750.0 0.01 -0.4901 -0.6937 2065678 ICCB6_000073 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D08 compound treatment 485423.0 -148000.0 -1.08 583202.0 -46200.0 -0.35 -1.0123 -0.8911 2065679 ICCB6_000074 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D09 compound treatment 638283.0 5120.0 0.04 602885.0 -26500.0 -0.2 -0.1161 -0.5662 2065680 ICCB6_000075 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)CCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D10 compound treatment 558231.0 -74900.0 -0.55 534324.0 -95100.0 -0.72 -0.8984 -0.9907 2065681 ICCB6_000076 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D11 compound treatment 629739.0 -3430.0 -0.03 683027.0 53600.0 0.41 0.2702 0.6623 2065682 ICCB6_000077 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D12 compound treatment 515407.0 -118000.0 -0.86 608460.0 -21000.0 -0.16 -0.7216 -0.8239 2065683 ICCB6_000078 CC(C)[Si](OCC(O)/C(=C\CO)/C)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D13 compound treatment 636616.0 3450.0 0.03 561438.0 -68000.0 -0.52 -0.3474 -0.6718 1952278 ICCB6_000079 COC(=O)c1nc(oc1C)C(NC(=O)CCc2cn(CC=C)c3ccccc23)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D14 compound treatment 592449.0 -40700.0 -0.3 579609.0 -49800.0 -0.38 -0.4782 -0.993 2065684 ICCB6_000080 CC(C)[Si](OCC(O)/C=C\CO)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D15 compound treatment 276913.0 -356000.0 -2.61 353513.0 -276000.0 -2.1 -3.3244 -0.9942 2065685 ICCB6_000081 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D16 compound treatment 461940.0 -171000.0 -1.25 407825.0 -222000.0 -1.68 -2.0758 -0.9894 2065686 ICCB6_000082 CC(C)[Si](OC[C@@H](O)[C@@]1(C)OC(C)(C)OC1CO)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D17 compound treatment 598033.0 -35100.0 -0.26 541045.0 -88400.0 -0.67 -0.6565 -0.9131 1952811 ICCB6_000083 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D18 compound treatment 522547.0 -111000.0 -0.81 546030.0 -83400.0 -0.63 -1.02 -0.9927 2065687 ICCB6_000084 CC(C)[Si](OC[C@@H](O)[C@H]1OC(C)(C)OC1CO)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D19 compound treatment 512158.0 -121000.0 -0.88 479356.0 -150000.0 -1.14 -1.4319 -0.9922 1952780 ICCB6_000085 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D20 compound treatment 581043.0 -52100.0 -0.38 660170.0 30700.0 0.23 -0.1044 -0.2336 2065688 ICCB6_000086 CC1(C)OC(CO)[C@H](O1)[C@H](O)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D21 compound treatment 598937.0 -34200.0 -0.25 556185.0 -73200.0 -0.56 -0.5705 -0.935 1952670 ICCB6_000087 COCCNC(=O)OC[C@H]1CCC[C@@]2(C[C@@H](C[C@@H](CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D22 compound treatment 590174.0 -43000.0 -0.31 615280.0 -14200.0 -0.11 -0.2983 -0.8978 2065689 ICCB6_000088 C/C(=C/CO)/[C@H](O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D23 mock treatment 646766.0 13600.0 0.1 595026.0 -34400.0 -0.26 -0.1145 -0.4094 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 D24 mock treatment 588843.0 -44300.0 -0.32 568347.0 -61100.0 -0.46 -0.5573 -0.9846 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E01 compound treatment 562042.0 -71100.0 -0.52 550262.0 -79200.0 -0.6 -0.7931 -0.9974 2065690 ICCB6_000089 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(Cl)c(Cl)c4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E02 compound treatment 529242.0 -104000.0 -0.76 538105.0 -91300.0 -0.69 -1.028 -0.999 2065691 ICCB6_000090 COc1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E03 compound treatment 351123.0 -282000.0 -2.06 391994.0 -237000.0 -1.8 -2.7339 -0.9978 2065692 ICCB6_000091 CCOC(=O)C1[C@@H](O[C@@H](CC1=O)c2ccccc2)C3CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E04 compound treatment 636587.0 3420.0 0.03 664966.0 35500.0 0.27 0.2086 0.7693 2065693 ICCB6_000092 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](O)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E05 compound treatment 303185.0 -330000.0 -2.41 427418.0 -202000.0 -1.53 -2.7915 -0.9761 2065694 ICCB6_000093 COc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)[Si](C)(C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E06 compound treatment 499816.0 -133000.0 -0.98 594740.0 -34700.0 -0.26 -0.8759 -0.8671 2065695 ICCB6_000094 CC(=O)OC/C=C/c1ccc(CCCCCCO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E07 compound treatment 526345.0 -107000.0 -0.78 581806.0 -47600.0 -0.36 -0.8082 -0.9388 2065696 ICCB6_000095 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E08 compound treatment 508226.0 -125000.0 -0.91 582757.0 -46700.0 -0.35 -0.8968 -0.915 2065697 ICCB6_000096 CCOC(=O)c1cccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E09 compound treatment 618518.0 -14600.0 -0.11 693319.0 63900.0 0.49 0.2674 0.5381 2065698 ICCB6_000097 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E10 compound treatment 540989.0 -92200.0 -0.67 517167.0 -112000.0 -0.85 -1.0797 -0.9932 2065699 ICCB6_000098 CCCCOC(=O)c1ccc(NC(=O)OC/C=C/c2ccc(CCCCCCO)o2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E11 compound treatment 482846.0 -150000.0 -1.1 720217.0 90800.0 0.69 -0.2896 -0.2232 1952474 ICCB6_000099 OCCCCCNC(CCO)Cc1ccc2ccccc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E12 compound treatment 478456.0 -155000.0 -1.13 437388.0 -192000.0 -1.46 -1.8316 -0.9921 2065700 ICCB6_000100 COC(=O)[C@@H](NC(=O)OC/C=C/c1ccc(CCCCCCO)o1)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E13 compound treatment 551546.0 -81600.0 -0.6 646485.0 17100.0 0.13 -0.3305 -0.541 1952280 ICCB6_000101 COC(=O)c1nc2oc1CC/C=C/Cn3cc(C[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C)c4ccccc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E14 compound treatment 551206.0 -82000.0 -0.6 571391.0 -58000.0 -0.44 -0.7356 -0.9886 2065701 ICCB6_000102 COc1cccc(Cl)c1NC(=O)OC/C=C/c2ccc(CCCCCCO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E15 compound treatment 572700.0 -60500.0 -0.44 582097.0 -47300.0 -0.36 -0.5669 -0.9947 1952487 ICCB6_000103 Fc1ccc(cc1Br)[C@H]2C3=CCn4n(C3C[C@@]5(C#N)C(=O)C(=C(Cl)C(=O)[C@@]25C#N)Cl)c(=O)n(c6ccccc6)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E16 compound treatment 517528.0 -116000.0 -0.85 602209.0 -27200.0 -0.21 -0.7442 -0.8548 2065702 ICCB6_000104 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E17 compound treatment 560972.0 -72200.0 -0.53 475639.0 -154000.0 -1.17 -1.1995 -0.9356 1952813 ICCB6_000105 OCCCC#Cc1cc(O)cc(Cl)c1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E18 compound treatment 657592.0 24400.0 0.18 682230.0 52800.0 0.4 0.4099 0.9336 2065703 ICCB6_000106 COc1cccc(c1)c2cc(oc2CCCCCCO)[C@@H](OC(=O)C)[C@H](C)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E19 compound treatment 565747.0 -67400.0 -0.49 641267.0 11800.0 0.09 -0.2851 -0.5688 3107406 ICCB6_000107 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E20 compound treatment 672959.0 39800.0 0.29 707031.0 77600.0 0.59 0.6226 0.9471 2065704 ICCB6_000108 C[C@@H]([C@H](OC(=O)C)c1cc(c(CCCCCCO)o1)c2ccccc2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E21 compound treatment 557827.0 -75300.0 -0.55 620846.0 -8580.0 -0.07 -0.4357 -0.7853 ICCB6_000109 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E22 compound treatment 651619.0 18500.0 0.13 701456.0 72000.0 0.55 0.4823 0.8559 2065705 ICCB6_000110 C[C@@H]([C@H](O)c1cc(c(CCCCCCO)o1)c2cccc(C)c2)C(=O)N3[C@@H](Cc4ccccc4)COC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E23 mock treatment 655155.0 22000.0 0.16 594156.0 -35300.0 -0.27 -0.0758 -0.2425 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 E24 mock treatment 527979.0 -105000.0 -0.77 613284.0 -16100.0 -0.12 -0.6307 -0.8096 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F01 compound treatment 592759.0 -40400.0 -0.3 631913.0 2480.0 0.02 -0.1956 -0.6606 2065706 ICCB6_000111 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccc(OC)cc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F02 compound treatment 500592.0 -133000.0 -0.97 559983.0 -69400.0 -0.53 -1.0586 -0.9591 2065707 ICCB6_000112 CC(C)[Si](OC[C@@H](O)C(C=C)C(O)c1ccccc1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F03 compound treatment 566441.0 -66700.0 -0.49 559076.0 -70400.0 -0.53 -0.723 -0.999 1009686 ICCB6_000113 O=C(CC(C(=O)c1ccccc1)c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F04 compound treatment 577636.0 -55500.0 -0.41 616732.0 -12700.0 -0.1 -0.3554 -0.8514 2065708 ICCB6_000114 OC/C=C\C(O)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F05 compound treatment 516724.0 -116000.0 -0.85 435678.0 -194000.0 -1.47 -1.6429 -0.9662 2065709 ICCB6_000115 CCCCCCCCNC(=O)CC[C@H]1O[C@H](O[C@H]2O[C@H](CCC(=O)NCCCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F06 compound treatment 445987.0 -187000.0 -1.37 571984.0 -57400.0 -0.44 -1.2765 -0.8885 2065710 ICCB6_000116 CC1=C([C@H](O)C(C)(C)C)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F07 compound treatment 577459.0 -55700.0 -0.41 551471.0 -78000.0 -0.59 -0.7068 -0.9833 2065711 ICCB6_000117 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F08 compound treatment 503598.0 -130000.0 -0.95 531873.0 -97600.0 -0.74 -1.1941 -0.9926 2065712 ICCB6_000118 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F09 compound treatment 555591.0 -77600.0 -0.57 611678.0 -17800.0 -0.13 -0.4965 -0.8515 2065713 ICCB6_000119 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F10 compound treatment 570518.0 -62600.0 -0.46 602780.0 -26700.0 -0.2 -0.4671 -0.9326 2065714 ICCB6_000120 C[C@@H](O)C1=CC[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F11 compound treatment 560308.0 -72900.0 -0.53 621566.0 -7860.0 -0.06 -0.419 -0.7815 1952476 ICCB6_000121 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2c(Br)sc3ccc(Cl)cc23)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F12 compound treatment 466669.0 -166000.0 -1.22 683785.0 54400.0 0.41 -0.569 -0.4426 2065715 ICCB6_000122 OC[C@@H]1[C@H]2[C@@H](CC=C1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F13 compound treatment 579482.0 -53700.0 -0.39 569624.0 -59800.0 -0.45 -0.5989 -0.9974 1952282 ICCB6_000123 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)NC2C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F14 compound treatment 512068.0 -121000.0 -0.89 507213.0 -122000.0 -0.93 -1.2827 -0.9997 2065716 ICCB6_000124 CC1=C(CO)[C@H](CO)[C@H]2[C@@H](C1)C(=O)N(Cc3ccccc3)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F15 compound treatment 580545.0 -52600.0 -0.38 548509.0 -80900.0 -0.61 -0.7068 -0.9746 1952488 ICCB6_000125 Fc1ccc(cc1Br)[C@H]2C3=CCC4=C(C3CC5=C2C(=O)C(=CC5=O)I)C(=O)C(=CC4=O)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F16 compound treatment 574517.0 -58600.0 -0.43 616483.0 -12900.0 -0.1 -0.3728 -0.8473 2065717 ICCB6_000126 C/C(=C/CO)/C(O)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F17 compound treatment 573103.0 -60100.0 -0.44 584926.0 -44500.0 -0.34 -0.5497 -0.9916 1952814 ICCB6_000127 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F18 compound treatment 375879.0 -257000.0 -1.88 427436.0 -202000.0 -1.53 -2.4155 -0.9949 2065718 ICCB6_000128 CC(C)[Si](OCC1OB(O)CC=C1C)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F19 compound treatment 516281.0 -117000.0 -0.85 510842.0 -119000.0 -0.9 -1.2415 -0.9997 1952785 ICCB6_000129 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F20 compound treatment 569598.0 -63600.0 -0.46 632608.0 3180.0 0.02 -0.3117 -0.6695 2065719 ICCB6_000130 OB1CC=C(C(O1)c2ccccc2)C(=C)COCc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F21 compound treatment 130097.0 -503000.0 -3.68 139872.0 -490000.0 -3.72 -5.2312 -1.0 3107360 ICCB6_000131 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F22 compound treatment 653712.0 20500.0 0.15 584770.0 -44700.0 -0.34 -0.1337 -0.3602 2065720 ICCB6_000132 OC/C=C(\C(O)c1ccccc1)/C(=C)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F23 mock treatment 641364.0 8200.0 0.06 583971.0 -45500.0 -0.35 -0.2018 -0.5757 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 F24 mock treatment 619194.0 -14000.0 -0.1 686201.0 56800.0 0.43 0.2327 0.525 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G01 compound treatment 562763.0 -70400.0 -0.51 585393.0 -44000.0 -0.33 -0.6006 -0.9782 2065721 ICCB6_000133 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4cccs4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G02 compound treatment 557237.0 -75900.0 -0.56 572737.0 -56700.0 -0.43 -0.6972 -0.9921 3057351 ICCB6_000134 CC(C)C[C@H](CI)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G03 compound treatment 564984.0 -68200.0 -0.5 515795.0 -114000.0 -0.86 -0.963 -0.966 2065722 ICCB6_000135 Clc1ccc(cc1)C(NP(=O)(c2ccccc2)c3ccccc3)C(=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G04 compound treatment 490105.0 -143000.0 -1.05 498847.0 -131000.0 -0.99 -1.4412 -0.9996 3057353 ICCB6_000136 CC(C)(C)OC[C@@H](O)[C@H]1O[C@H](NO)C2OC(C)(C)OC12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G05 compound treatment 564770.0 -68400.0 -0.5 576566.0 -52900.0 -0.4 -0.6377 -0.9941 2065723 ICCB6_000137 CCCCCCCNCC(=O)NC[C@H]1O[C@H](O[C@H]2O[C@H](CNC(=O)CCNCCCCCC)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G06 compound treatment 563486.0 -69700.0 -0.51 600056.0 -29400.0 -0.22 -0.5181 -0.9314 2065724 ICCB6_000138 CC(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G07 compound treatment 519126.0 -114000.0 -0.83 574438.0 -55000.0 -0.42 -0.8851 -0.9489 2065725 ICCB6_000139 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G08 compound treatment 549793.0 -83400.0 -0.61 578534.0 -50900.0 -0.39 -0.7045 -0.9758 2065726 ICCB6_000140 CC(C)(C)[Si](C)(C)OCC1=CC(C#C)N(C=C1)C(=O)c2ccccc2Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G09 compound treatment 660998.0 27800.0 0.2 695645.0 66200.0 0.5 0.4996 0.9207 2065727 ICCB6_000141 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G10 compound treatment 621900.0 -11300.0 -0.08 730577.0 101000.0 0.77 0.4851 0.6277 3057357 ICCB6_000142 OC(=O)c1[se]c2ccccc2c1Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G11 compound treatment 496240.0 -137000.0 -1.0 562964.0 -66500.0 -0.5 -1.0651 -0.9498 1952478 ICCB6_000143 OCCCCCN(Cc1ccccc1Br)[C@@H](COCc2ccc3ccccc3c2Br)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G12 compound treatment 435470.0 -198000.0 -1.45 498625.0 -131000.0 -0.99 -1.725 -0.9833 3057359 ICCB6_000144 CC(C)(C)[Si](C)(C)OCC1=CC(C=C)N(C=C1)C(=O)c2[se]c3ccccc3c2Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G13 compound treatment 570284.0 -62900.0 -0.46 669178.0 39700.0 0.3 -0.1117 -0.203 1952284 ICCB6_000145 COC(=O)c1nc2oc1CC/C=C/CNC(=O)O[C@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@H]2C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G14 compound treatment 498040.0 -135000.0 -0.99 585546.0 -43900.0 -0.33 -0.9345 -0.896 2065728 ICCB6_000146 CCCCCC1C=C(CO[Si](C)(C)C(C)(C)C)C=CN1C(=O)c2ccccc2Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G15 compound treatment 666397.0 33200.0 0.24 564367.0 -65100.0 -0.49 -0.1777 -0.3226 2065729 ICCB6_000147 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G16 compound treatment 593922.0 -39200.0 -0.29 537377.0 -92100.0 -0.7 -0.6974 -0.9226 2065730 ICCB6_000148 CC(C)(C)[Si](C)(C)Oc1cccc2C(C=C)N(C=Cc12)C(=O)c3ccccc3Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G17 compound treatment 806178.0 173000.0 1.27 687094.0 57700.0 0.44 1.2044 0.8995 1952760 ICCB6_000149 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G18 compound treatment 687782.0 54600.0 0.4 550058.0 -79400.0 -0.6 -0.1439 -0.199 2065731 ICCB6_000150 CC(=O)N[C@@H](CI)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G19 compound treatment 717828.0 84700.0 0.62 632408.0 2980.0 0.02 0.4538 0.7324 1952788 ICCB6_000151 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G20 compound treatment 671313.0 38100.0 0.28 629504.0 73.3 0.0 0.1977 0.7085 2065732 ICCB6_000152 COc1cc2CCN(Cc3ccccc3Br)C(C=C)c2cc1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G21 compound treatment 487110.0 -146000.0 -1.07 579534.0 -49900.0 -0.38 -1.0233 -0.9029 1952728 ICCB6_000153 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G22 compound treatment 677574.0 44400.0 0.32 614552.0 -14900.0 -0.11 0.1497 0.4354 2065733 ICCB6_000154 CN1C(=O)C2C(C1=O)C3(C4C(C5C=C(CCCO[Si](C)(C)C(C)(C)C)CC2N53)C(=O)N(C)C4=O)C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G23 mock treatment 704305.0 71100.0 0.52 633790.0 4360.0 0.03 0.3913 0.7506 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 G24 mock treatment 561343.0 -71800.0 -0.53 620915.0 -8520.0 -0.06 -0.4171 -0.7882 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H01 compound treatment 648571.0 15400.0 0.11 568563.0 -60900.0 -0.46 -0.2473 -0.5196 2065734 ICCB6_000155 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4Cl)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H02 compound treatment 433998.0 -199000.0 -1.46 649578.0 20100.0 0.15 -0.9217 -0.6293 2065735 ICCB6_000156 CC(=C)C1=CCB(O)OC1c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H03 compound treatment 476486.0 -157000.0 -1.15 560559.0 -68900.0 -0.52 -1.1802 -0.9369 2065736 ICCB6_000157 CC(C(NP(=O)(c1ccccc1)c2ccccc2)c3ccccc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H04 compound treatment 412046.0 -221000.0 -1.62 608656.0 -20800.0 -0.16 -1.255 -0.7724 2065737 ICCB6_000158 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H05 compound treatment 561200.0 -72000.0 -0.53 632035.0 2600.0 0.02 -0.3582 -0.68 2065738 ICCB6_000159 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H06 compound treatment 556024.0 -77100.0 -0.56 552500.0 -76900.0 -0.58 -0.8122 -0.9998 2065739 ICCB6_000160 CC(=C)/C(=C/CO)/C(O)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H07 compound treatment 568151.0 -65000.0 -0.48 576674.0 -52800.0 -0.4 -0.6196 -0.9964 2065740 ICCB6_000161 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C)N1C(=O)Cc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H08 compound treatment 449504.0 -184000.0 -1.34 572887.0 -56500.0 -0.43 -1.2535 -0.8889 2065741 ICCB6_000162 CC1=NC(C)(C)[C@@H]2CCC(=C)C1C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H09 compound treatment 608233.0 -24900.0 -0.18 624469.0 -4960.0 -0.04 -0.1556 -0.8356 2065742 ICCB6_000163 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H10 compound treatment 558172.0 -75000.0 -0.55 577240.0 -52200.0 -0.4 -0.6682 -0.9873 2065743 ICCB6_000164 C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H11 compound treatment 618619.0 -14500.0 -0.11 665247.0 35800.0 0.27 0.1172 0.4011 1952534 ICCB6_000165 C[C@H](N)C(Oc1ccccc1Br)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H12 compound treatment 444157.0 -189000.0 -1.38 674134.0 44700.0 0.34 -0.7373 -0.518 2065744 ICCB6_000166 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H13 compound treatment 668331.0 35200.0 0.26 579024.0 -50400.0 -0.38 -0.0889 -0.1928 1952286 ICCB6_000167 COC(=O)c1nc(oc1CCC=C)C(NC(=O)[C@H](Cc2cn(CC=C)cn2)NC(=O)OCc3ccccc3)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H14 compound treatment 625244.0 -7920.0 -0.06 511800.0 -118000.0 -0.89 -0.6728 -0.7514 2065745 ICCB6_000168 CC(C)C[C@H]1NC(C)(C)C2CCC(=C)[C@H]1C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H15 compound treatment 365456.0 -268000.0 -1.96 423232.0 -206000.0 -1.57 -2.492 -0.9939 1952677 ICCB6_000169 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H16 compound treatment 714112.0 80900.0 0.59 663704.0 34300.0 0.26 0.6027 0.932 2065746 ICCB6_000170 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H17 compound treatment 464818.0 -168000.0 -1.23 457757.0 -172000.0 -1.3 -1.7927 -0.9996 1952821 ICCB6_000171 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H18 compound treatment 626585.0 -6580.0 -0.05 613954.0 -15500.0 -0.12 -0.1172 -0.9223 2065747 ICCB6_000172 COc1cc(C[C@H]2NC(C)(C)C3CCC(=C)[C@H]2C3)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H19 compound treatment 628323.0 -4840.0 -0.04 545881.0 -83500.0 -0.63 -0.4738 -0.7454 1952600 ICCB6_000173 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H20 compound treatment 705531.0 72400.0 0.53 520760.0 -109000.0 -0.83 -0.2095 -0.2137 2065748 ICCB6_000174 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2C)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H21 compound treatment 543004.0 -90200.0 -0.66 600888.0 -28500.0 -0.22 -0.6196 -0.8926 1952730 ICCB6_000175 O=c1cc(Cc2ccccc2)c3ccccc3o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H22 compound treatment 605988.0 -27200.0 -0.2 662251.0 32800.0 0.25 0.0358 0.1122 2065749 ICCB6_000176 CC1(C)N=C(/C=C/2\C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H23 mock treatment 635151.0 1990.0 0.01 648698.0 19300.0 0.15 0.1138 0.7735 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 H24 mock treatment 617604.0 -15600.0 -0.11 683480.0 54000.0 0.41 0.2099 0.4926 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I01 compound treatment 625425.0 -7740.0 -0.06 620159.0 -9270.0 -0.07 -0.0898 -0.9941 2065750 ICCB6_000177 COC(=O)[C@@H]1[C@H](N([C@H](c2ccccc2)[C@@]13C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6)C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I02 compound treatment 566719.0 -66400.0 -0.49 666929.0 37500.0 0.28 -0.1422 -0.2524 2065751 ICCB6_000178 CC(C)(C)[Si](C)(C)OCCCC1=CC2C3C(C(=O)N(Cc4ccccc4)C3=O)C5(C6C(C(C1)N25)C(=O)N(Cc7ccccc7)C6=O)C(=O)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I03 compound treatment 583648.0 -49500.0 -0.36 553923.0 -75500.0 -0.57 -0.6617 -0.9754 2065752 ICCB6_000179 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Cl)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I04 compound treatment 592249.0 -40900.0 -0.3 688054.0 58600.0 0.45 0.1033 0.1926 2065753 ICCB6_000180 COc1cc(CN[C@@H](C)[C@H](Oc2ccccc2Br)c3ccccc3)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I05 compound treatment 540964.0 -92200.0 -0.67 669919.0 40500.0 0.31 -0.2593 -0.3499 2065754 ICCB6_000181 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I06 compound treatment 601439.0 -31700.0 -0.23 591894.0 -37500.0 -0.29 -0.3657 -0.9948 2065755 ICCB6_000182 COc1cc(CN[C@H]([C@H](O)c2ccccc2)c3ccccc3)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I07 compound treatment 674124.0 41000.0 0.3 645841.0 16400.0 0.12 0.3 0.9245 2065756 ICCB6_000183 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I08 compound treatment 445400.0 -188000.0 -1.37 570026.0 -59400.0 -0.45 -1.2901 -0.8925 2065757 ICCB6_000184 COc1cc(CN(Cc2ccccc2Br)[C@H]([C@H](O)c3ccccc3)c4ccccc4)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I09 compound treatment 665145.0 32000.0 0.23 730479.0 101000.0 0.77 0.7082 0.8825 2065758 ICCB6_000185 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I10 compound treatment 592645.0 -40500.0 -0.3 627364.0 -2070.0 -0.02 -0.2206 -0.7435 2065759 ICCB6_000186 COc1cc(CN(Cc2ccccc2Br)[C@H](C)C(Oc3ccccc3Br)c4ccccc4)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I11 compound treatment 685274.0 52100.0 0.38 685273.0 55800.0 0.42 0.5694 0.9986 1952544 ICCB6_000187 O=C1Nc2ccccc2[C@@]31[C@@H](C#N)C4N([C@H]3c5ccccc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I12 compound treatment 595275.0 -37900.0 -0.28 611112.0 -18300.0 -0.14 -0.2943 -0.9492 2065760 ICCB6_000188 COc1cc(CN(Cc2ccccc2Br)[C@H](C(Oc3ccccc3Br)c4ccccc4)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I13 compound treatment 620555.0 -12600.0 -0.09 605503.0 -23900.0 -0.18 -0.1937 -0.9505 1952288 ICCB6_000189 COC(=O)c1nc2oc1CC/C=C/Cn3cnc(C[C@H](NC(=O)OCc4ccccc4)C(=O)NC2C(C)C)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I14 compound treatment 661128.0 28000.0 0.2 602942.0 -26500.0 -0.2 0.0023 0.008 2065761 ICCB6_000190 C[C@@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I15 compound treatment 702058.0 68900.0 0.5 667394.0 38000.0 0.29 0.5602 0.965 1952679 ICCB6_000191 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I16 compound treatment 671332.0 38200.0 0.28 521997.0 -107000.0 -0.82 -0.3797 -0.4403 2065762 ICCB6_000192 C[C@H](C(Oc1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])c2ccccc2)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I17 compound treatment 531242.0 -102000.0 -0.75 455888.0 -174000.0 -1.32 -1.4593 -0.9636 1952823 ICCB6_000193 C#Cc1ccccc1Oc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I18 compound treatment 660118.0 27000.0 0.2 592600.0 -36800.0 -0.28 -0.0585 -0.1708 2065763 ICCB6_000194 C[C@H](C(Oc1ccc(cc1)[N+](=O)[O-])c2ccccc2)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I19 compound treatment 259944.0 -373000.0 -2.73 314559.0 -315000.0 -2.39 -3.6214 -0.9978 1952601 ICCB6_000195 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I20 compound treatment 750865.0 118000.0 0.86 666887.0 37500.0 0.28 0.8098 0.8933 2065764 ICCB6_000196 C[C@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I21 compound treatment 556884.0 -76300.0 -0.56 454162.0 -175000.0 -1.33 -1.336 -0.9254 1952746 ICCB6_000197 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I22 compound treatment 715048.0 81900.0 0.6 636624.0 7190.0 0.05 0.4621 0.7684 2065765 ICCB6_000198 C[C@@H]([C@@H](Oc1ccccc1Br)c2ccccc2)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I23 mock treatment 590386.0 -42800.0 -0.31 605523.0 -23900.0 -0.18 -0.3496 -0.9665 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 I24 mock treatment 612091.0 -21100.0 -0.15 607938.0 -21500.0 -0.16 -0.2244 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J01 compound treatment 396949.0 -236000.0 -1.73 382475.0 -247000.0 -1.88 -2.5481 -0.9992 2065766 ICCB6_000199 COC(=O)C1=CN([C@H](c2ccccc2)[C@]31C(=O)N(Cc4ccccc4)c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J02 compound treatment 505929.0 -127000.0 -0.93 587391.0 -42000.0 -0.32 -0.8838 -0.8984 2065767 ICCB6_000200 CC1(C)N[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC1CCC4=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J03 compound treatment 561744.0 -71400.0 -0.52 632293.0 2860.0 0.02 -0.354 -0.6771 2065768 ICCB6_000201 CCOC(=O)[C@H]1N(C(C(=C1C(=O)OC)C(=O)OC)c2ccc(Br)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J04 compound treatment 649119.0 16000.0 0.12 680372.0 50900.0 0.39 0.3561 0.8811 2065769 ICCB6_000202 CN1[C@H](CC2C(=O)Nc3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J05 compound treatment 665111.0 31900.0 0.23 597053.0 -32400.0 -0.25 -0.0087 -0.0257 2065770 ICCB6_000203 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J06 compound treatment 489810.0 -143000.0 -1.05 471311.0 -158000.0 -1.2 -1.5907 -0.9977 2065771 ICCB6_000204 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J07 compound treatment 759871.0 127000.0 0.93 801639.0 172000.0 1.31 1.5803 0.9857 2065772 ICCB6_000205 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J08 compound treatment 525595.0 -108000.0 -0.79 588562.0 -40900.0 -0.31 -0.7758 -0.9173 2065773 ICCB6_000206 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J09 compound treatment 630184.0 -2980.0 -0.02 715407.0 86000.0 0.65 0.4464 0.6831 2065774 ICCB6_000207 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](CC(C)C)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J10 compound treatment 441802.0 -191000.0 -1.4 397035.0 -232000.0 -1.77 -2.2379 -0.9934 2065775 ICCB6_000208 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J11 compound treatment 653749.0 20600.0 0.15 594727.0 -34700.0 -0.26 -0.08 -0.2635 2065776 ICCB6_000209 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J12 compound treatment 725633.0 92500.0 0.68 668825.0 39400.0 0.3 0.6898 0.9328 2065777 ICCB6_000210 OCCOc1cccc(c1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J13 compound treatment 480646.0 -153000.0 -1.12 514796.0 -115000.0 -0.87 -1.4045 -0.9925 1952295 ICCB6_000211 COC(=O)c1nc(oc1CC(=O)CCl)C(NC(=O)NC(=O)OC(C)(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J14 compound treatment 481431.0 -152000.0 -1.11 600584.0 -28800.0 -0.22 -0.9396 -0.8307 2065778 ICCB6_000212 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J15 compound treatment 669122.0 36000.0 0.26 529053.0 -100000.0 -0.76 -0.3533 -0.438 1952690 ICCB6_000213 COC(=O)CC(C(=O)OC)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J16 compound treatment 767674.0 135000.0 0.98 527863.0 -102000.0 -0.77 0.15 0.12 2065779 ICCB6_000214 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC(C(=O)OC)C(=O)OC)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J17 compound treatment 614229.0 -18900.0 -0.14 644522.0 15100.0 0.11 -0.0169 -0.0938 1952825 ICCB6_000215 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J18 compound treatment 750514.0 117000.0 0.86 647245.0 17800.0 0.14 0.7025 0.8086 2065780 ICCB6_000216 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J19 compound treatment 321649.0 -312000.0 -2.28 257741.0 -372000.0 -2.82 -3.6075 -0.9943 1952605 ICCB6_000217 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J20 compound treatment 655461.0 22300.0 0.16 698155.0 68700.0 0.52 0.4845 0.8857 2065781 ICCB6_000218 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J21 compound treatment 737237.0 104000.0 0.76 668074.0 38600.0 0.29 0.7458 0.9142 3005760 ICCB6_000219 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J22 compound treatment 728316.0 95200.0 0.7 613560.0 -15900.0 -0.12 0.4068 0.576 2065782 ICCB6_000220 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCNC(=O)N)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J23 mock treatment 752205.0 119000.0 0.87 565706.0 -63700.0 -0.48 0.2733 0.2743 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 J24 mock treatment 633323.0 157.0 0.0 657854.0 28400.0 0.22 0.1535 0.7109 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K01 compound treatment 565028.0 -68100.0 -0.5 531304.0 -98100.0 -0.75 -0.8795 -0.9808 2065783 ICCB6_000221 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C)c5ccccc52 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K02 compound treatment 546877.0 -86300.0 -0.63 599638.0 -29800.0 -0.23 -0.6063 -0.9043 2065784 ICCB6_000222 CC(Oc1ccccc1Br)[C@H](N(C)C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K03 compound treatment 581366.0 -51800.0 -0.38 623847.0 -5580.0 -0.04 -0.2979 -0.7814 2065785 ICCB6_000223 COC(=O)C(C(c1ccc(OC)cc1)[Si](C)(C)c2ccccc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K04 compound treatment 604305.0 -28900.0 -0.21 627004.0 -2430.0 -0.02 -0.1623 -0.766 2065786 ICCB6_000224 C[C@H](C(Oc1ccccc1[N+](=O)[O-])c2ccccc2)N(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K05 compound treatment 710527.0 77400.0 0.57 652112.0 22700.0 0.17 0.5219 0.8824 2065787 ICCB6_000225 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K06 compound treatment 466643.0 -167000.0 -1.22 564232.0 -65200.0 -0.5 -1.2113 -0.9214 2065788 ICCB6_000226 COc1cc(/C=C/C=O)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K07 compound treatment 656333.0 23200.0 0.17 680293.0 50900.0 0.39 0.393 0.9315 2065789 ICCB6_000227 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)CCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K08 compound treatment 605369.0 -27800.0 -0.2 605170.0 -24300.0 -0.18 -0.2741 -0.9988 2065790 ICCB6_000228 COc1cc(/C=C/CN[C@H](C)[C@@H](O)c2ccccc2)ccc1O[Si](C(C)C)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K09 compound treatment 661285.0 28100.0 0.21 695604.0 66200.0 0.5 0.5009 0.9222 2065791 ICCB6_000229 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](CC(C)C)N1C(=O)Cc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K10 compound treatment 666683.0 33500.0 0.25 611622.0 -17800.0 -0.14 0.0777 0.2774 2065792 ICCB6_000230 CC(C)[Si](OCC1CCC=CC1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K11 compound treatment 584971.0 -48200.0 -0.35 668048.0 38600.0 0.29 -0.0418 -0.0911 1034979 ICCB6_000231 c1c(cn2ccccc12)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K12 compound treatment 654474.0 21300.0 0.16 636167.0 6740.0 0.05 0.1464 0.8924 2065793 ICCB6_000232 CC1(C)COC(=O)C1OC(=O)C2CC3CCC2C=C3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K13 compound treatment 659292.0 26100.0 0.19 570763.0 -58700.0 -0.45 -0.18 -0.3713 1952379 ICCB6_000233 CC(C)[Si](OCc1ccc(C=O)o1)(C(C)C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K14 compound treatment 675198.0 42000.0 0.31 584609.0 -44800.0 -0.34 -0.0234 -0.051 2065794 ICCB6_000234 OCC1CC2CCC1C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K15 compound treatment 662694.0 29500.0 0.22 554288.0 -75100.0 -0.57 -0.251 -0.4112 1952707 ICCB6_000235 CCCCSc1cc(=O)oc2cc(OC)ccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K16 compound treatment 142020.0 -491000.0 -3.59 145962.0 -483000.0 -3.67 -5.1369 -0.9999 2065795 ICCB6_000236 Ic1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K17 compound treatment 189265.0 -444000.0 -3.25 180657.0 -449000.0 -3.41 -4.7062 -0.9997 1952828 ICCB6_000237 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K18 compound treatment 656636.0 23500.0 0.17 590331.0 -39100.0 -0.3 -0.0887 -0.2585 2065796 ICCB6_000238 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3cccnc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K19 compound treatment 684970.0 51800.0 0.38 608599.0 -20800.0 -0.16 0.156 0.3799 1952608 ICCB6_000239 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K20 compound treatment 640719.0 7550.0 0.06 631521.0 2090.0 0.02 0.0503 0.8749 2065797 ICCB6_000240 C=CCOC(=O)[C@H]1[C@H]2N([C@@H](c3ccco3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K21 compound treatment 739594.0 106000.0 0.78 590517.0 -38900.0 -0.3 0.3413 0.41 3005761 ICCB6_000241 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K22 compound treatment 138311.0 -495000.0 -3.62 127060.0 -502000.0 -3.82 -5.2576 -0.9996 2065798 ICCB6_000242 Ic1ccc2NC(=O)/C(=C/C#N)/c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K23 mock treatment 642314.0 9150.0 0.07 643152.0 13700.0 0.1 0.121 0.977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 K24 mock treatment 631450.0 -1720.0 -0.01 627426.0 -2000.0 -0.02 -0.0196 -0.9954 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L01 compound treatment 544402.0 -88800.0 -0.65 725710.0 96300.0 0.73 0.0582 0.0595 2065799 ICCB6_000243 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccccc52 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L02 compound treatment 528873.0 -104000.0 -0.76 661969.0 32500.0 0.25 -0.3645 -0.4547 2065800 ICCB6_000244 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#Cc6ccccc6F)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L03 compound treatment 635803.0 2640.0 0.02 664931.0 35500.0 0.27 0.2043 0.7557 2065801 ICCB6_000245 COC(=O)C(C(c1ccco1)[Si](C)(C)c2ccccc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L04 compound treatment 693222.0 60100.0 0.44 720296.0 90900.0 0.69 0.7987 0.9762 2065802 ICCB6_000246 CCCCC[C@H](O)C#Cc1ccc2NC(=O)[C@@]3([C@H](C4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N(C)OC)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L05 compound treatment 644744.0 11600.0 0.08 700430.0 71000.0 0.54 0.4413 0.8082 2065803 ICCB6_000247 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L06 compound treatment 723275.0 90100.0 0.66 840083.0 211000.0 1.6 1.5975 0.9231 2065804 ICCB6_000248 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)[C@H](C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L07 compound treatment 674794.0 41600.0 0.3 640230.0 10800.0 0.08 0.2733 0.8667 2065805 ICCB6_000249 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L08 compound treatment 485331.0 -148000.0 -1.08 534217.0 -95200.0 -0.72 -1.2759 -0.9809 2065806 ICCB6_000250 OCCOc1ccc(cc1)C2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L09 compound treatment 599486.0 -33700.0 -0.25 679949.0 50500.0 0.38 0.0972 0.2132 2065807 ICCB6_000251 CCOC(=O)CC1[C@@H]2[C@@H](NCc3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L10 compound treatment 749305.0 116000.0 0.85 626144.0 -3290.0 -0.02 0.5829 0.686 2065808 ICCB6_000252 CON(C)C(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(I)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L11 compound treatment 674455.0 41300.0 0.3 593212.0 -36200.0 -0.28 0.019 0.0464 2065809 ICCB6_000253 COC(=O)Cc1cn[nH]c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L12 compound treatment 476290.0 -157000.0 -1.15 513636.0 -116000.0 -0.88 -1.4332 -0.9914 2065810 ICCB6_000254 CCOC(=O)[C@H]1[C@H]2N(C(c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(Br)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L13 compound treatment 184587.0 -449000.0 -3.28 210753.0 -419000.0 -3.18 -4.5687 -0.9999 1952411 ICCB6_000255 CC(C)[Si](OCc1ccc(o1)[C@@H](O)[C@H](C)C(=O)N2[C@@H](C)[C@H](OC2=O)c3ccccc3)(C(C)C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L14 compound treatment 548715.0 -84500.0 -0.62 510429.0 -119000.0 -0.9 -1.076 -0.9827 2065811 ICCB6_000256 OCCOc1ccc(cc1)C2N3[C@H]([C@H](C(=O)OCC=C)[C@@]24C(=O)Nc5ccc(Br)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L15 compound treatment 682157.0 49000.0 0.36 551904.0 -77500.0 -0.59 -0.1631 -0.2366 1952793 ICCB6_000257 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L16 compound treatment 763090.0 130000.0 0.95 574867.0 -54600.0 -0.41 0.3788 0.3654 2065812 ICCB6_000258 CON(C)C(=O)[C@H]1C2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L17 compound treatment 665709.0 32500.0 0.24 544313.0 -85100.0 -0.65 -0.2889 -0.4193 1952829 ICCB6_000259 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L18 compound treatment 452584.0 -181000.0 -1.32 475549.0 -154000.0 -1.17 -1.7604 -0.9982 2065813 ICCB6_000260 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)OCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L19 compound treatment 643034.0 9870.0 0.07 580436.0 -49000.0 -0.37 -0.2122 -0.5596 1952582 ICCB6_000261 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CC[C@@H]2C[C@H](C[C@@]3(CCC[C@H](COC(=O)NCCOC)O3)O2)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L20 compound treatment 708529.0 75400.0 0.55 555257.0 -74200.0 -0.56 -0.0087 -0.0111 2065814 ICCB6_000262 CON(C)C(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(Br)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L21 compound treatment 789181.0 156000.0 1.14 659906.0 30500.0 0.23 0.9705 0.8336 1952748 ICCB6_000263 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L22 compound treatment 636666.0 3500.0 0.03 596470.0 -33000.0 -0.25 -0.159 -0.6315 2065815 ICCB6_000264 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L23 mock treatment 711815.0 78600.0 0.58 628971.0 -460.0 0.0 0.4042 0.7028 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 L24 mock treatment 644549.0 11400.0 0.08 647619.0 18200.0 0.14 0.1566 0.9706 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M01 compound treatment 134679.0 -498000.0 -3.65 158367.0 -471000.0 -3.58 -5.1082 -1.0 2065816 ICCB6_000265 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccccc3)c4ccccc4)C(=O)N(C(=O)C)c5ccc(Cl)cc52 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M02 compound treatment 695977.0 62800.0 0.46 759040.0 130000.0 0.98 1.021 0.9398 2065817 ICCB6_000266 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M03 compound treatment 724681.0 91500.0 0.67 789383.0 160000.0 1.22 1.3325 0.9605 2065818 ICCB6_000267 COc1ccc(cc1)C(CC(=O)c2ccccc2)[Si](C)(C)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M04 compound treatment 552730.0 -80400.0 -0.59 686503.0 57100.0 0.43 -0.1094 -0.1497 2065819 ICCB6_000268 OCc1ccc(o1)[C@@H]2N3[C@H]([C@H](C#N)[C@@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M05 compound treatment 741951.0 109000.0 0.8 822210.0 193000.0 1.46 1.5981 0.9589 2065820 ICCB6_000269 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M06 compound treatment 391188.0 -242000.0 -1.77 626281.0 -3150.0 -0.02 -1.2682 -0.7166 2065821 ICCB6_000270 COC(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M07 compound treatment 649416.0 16300.0 0.12 730709.0 101000.0 0.77 0.6281 0.8068 2065822 ICCB6_000271 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M08 compound treatment 681448.0 48300.0 0.35 852129.0 223000.0 1.69 1.446 0.8367 2065823 ICCB6_000272 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCC4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M09 compound treatment 795743.0 163000.0 1.19 800585.0 171000.0 1.3 1.7601 0.999 2065824 ICCB6_000273 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](Cc4ccccc4)N1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M10 compound treatment 592415.0 -40800.0 -0.3 734446.0 105000.0 0.8 0.3534 0.415 2065825 ICCB6_000274 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCc4ccccc4)[C@]25C(=O)Nc6ccc(I)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M11 compound treatment 673576.0 40400.0 0.3 708387.0 79000.0 0.6 0.6331 0.9468 2065826 ICCB6_000275 CC(C(=O)O)c1ccccc1C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M12 compound treatment 580544.0 -52600.0 -0.38 866022.0 237000.0 1.8 0.9988 0.5434 2065827 ICCB6_000276 OCCNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(I)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M13 compound treatment 630664.0 -2500.0 -0.02 520921.0 -109000.0 -0.82 -0.5958 -0.7226 1952416 ICCB6_000277 Clc1c(Cl)c(Cl)c(OCc2ccccc2)c(Cl)c1Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M14 compound treatment 541845.0 -91300.0 -0.67 546396.0 -83000.0 -0.63 -0.9183 -0.9996 2065828 ICCB6_000278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M15 compound treatment 675168.0 42000.0 0.31 685098.0 55700.0 0.42 0.5162 0.9877 1952795 ICCB6_000279 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M16 compound treatment 767278.0 134000.0 0.98 758807.0 129000.0 0.98 1.3885 1.0 2065829 ICCB6_000280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)C(C(OC3=O)c5ccccc5)c6ccccc6)C(=O)N(C)OC)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M17 compound treatment 659904.0 26700.0 0.2 782493.0 153000.0 1.16 0.9605 0.8146 1952832 ICCB6_000281 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M18 compound treatment 823253.0 190000.0 1.39 846894.0 217000.0 1.65 2.1511 0.9963 3176523 ICCB6_000282 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCC(C)C)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M19 compound treatment 587707.0 -45500.0 -0.33 634606.0 5180.0 0.04 -0.2073 -0.6192 1952627 ICCB6_000283 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M20 compound treatment 810247.0 177000.0 1.3 848493.0 219000.0 1.66 2.0925 0.9923 3056713 ICCB6_000284 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@@H](C(C)C)C(=O)OC)c5ccc(C#CC6(O)CCCCCC6)cc54)C(C(OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M21 compound treatment 350969.0 -282000.0 -2.06 406120.0 -223000.0 -1.7 -2.6588 -0.9953 1107217 ICCB6_000285 Cc1cccnc1I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M22 compound treatment 711263.0 78100.0 0.57 813822.0 184000.0 1.4 1.3944 0.9217 3176524 ICCB6_000286 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)N[C@H](C)c5ccccc5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M23 mock treatment 645738.0 12600.0 0.09 738600.0 109000.0 0.83 0.6514 0.7807 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 M24 mock treatment 552738.0 -80400.0 -0.59 639020.0 9590.0 0.07 -0.3644 -0.6148 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N01 compound treatment 712659.0 79500.0 0.58 674521.0 45100.0 0.34 0.6533 0.9682 2065830 ICCB6_000287 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3ccc(Cl)cc3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N02 compound treatment 763676.0 131000.0 0.95 839022.0 210000.0 1.59 1.8008 0.97 2065831 ICCB6_000288 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCN(C)Cc6ccccc6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N03 compound treatment 649487.0 16300.0 0.12 698855.0 69400.0 0.53 0.4573 0.8457 2065832 ICCB6_000289 C[Si](C)(F)C(CC(=O)c1ccccc1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N04 compound treatment 643524.0 10400.0 0.08 595273.0 -34200.0 -0.26 -0.1299 -0.4806 2065833 ICCB6_000290 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N(C)OC)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N05 compound treatment 716482.0 83300.0 0.61 866118.0 237000.0 1.8 1.7023 0.8966 2065834 ICCB6_000291 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)CN1C(=O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N06 compound treatment 713822.0 80700.0 0.59 846481.0 217000.0 1.65 1.583 0.904 2065835 ICCB6_000292 CC1(C)N[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC1CCC4=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N07 compound treatment 749266.0 116000.0 0.85 642229.0 12800.0 0.1 0.6691 0.783 2065836 ICCB6_000293 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)[C@H](C(C)C)N1C(=O)Cc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N08 compound treatment 657601.0 24400.0 0.18 759831.0 130000.0 0.99 0.8268 0.8214 2065837 ICCB6_000294 CN1[C@H](Cc2c[nH]c3ccccc23)[C@@H]4CC(CCC4=C)C1(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N09 compound treatment 804846.0 172000.0 1.26 769562.0 140000.0 1.06 1.6405 0.9966 2065838 ICCB6_000295 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)CCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N10 compound treatment 703167.0 70000.0 0.51 634068.0 4640.0 0.04 0.3869 0.754 2065839 ICCB6_000296 Cc1ccc(cc1)S(=O)(=O)N[C@H]2CC3CCC2(C)C3(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N11 compound treatment 682747.0 49600.0 0.36 698556.0 69100.0 0.53 0.6277 0.9836 2065840 ICCB6_000297 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N12 compound treatment 578055.0 -55100.0 -0.4 763731.0 134000.0 1.02 0.4364 0.3979 2065841 ICCB6_000298 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCC6CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N13 compound treatment 674099.0 40900.0 0.3 655673.0 26200.0 0.2 0.3526 0.9805 1952445 ICCB6_000299 Clc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccc(CNC(=O)OCc5ccccc5)cc4)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N14 compound treatment 663721.0 30600.0 0.22 605381.0 -24000.0 -0.18 0.0288 0.0998 2065842 ICCB6_000300 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N15 compound treatment 794346.0 161000.0 1.18 738184.0 109000.0 0.83 1.4177 0.9849 1952801 ICCB6_000301 Oc1ccccc1C#Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N16 compound treatment 763451.0 130000.0 0.95 845736.0 216000.0 1.64 1.8357 0.9664 2065843 ICCB6_000302 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N17 compound treatment 468967.0 -164000.0 -1.2 532710.0 -96700.0 -0.73 -1.3687 -0.9722 1952836 ICCB6_000303 CC(=O)c1ccc2oc(cc2c1)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N18 compound treatment 626397.0 -6770.0 -0.05 602318.0 -27100.0 -0.21 -0.1806 -0.8528 2065844 ICCB6_000304 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N19 compound treatment 706230.0 73100.0 0.53 792390.0 163000.0 1.24 1.2532 0.9294 1952631 ICCB6_000305 CCOC(=O)[C@H](CC(C)C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N20 compound treatment 758046.0 125000.0 0.91 689858.0 60400.0 0.46 0.9704 0.9494 2065845 ICCB6_000306 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N21 compound treatment 476712.0 -156000.0 -1.14 625564.0 -3870.0 -0.03 -0.8298 -0.725 3005761 ICCB6_000307 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N22 compound treatment 696626.0 63500.0 0.46 632174.0 2740.0 0.02 0.3429 0.7381 2065846 ICCB6_000308 CN(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)Cc8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N23 mock treatment 676279.0 43100.0 0.32 642876.0 13400.0 0.1 0.2952 0.8906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 N24 mock treatment 628890.0 -4280.0 -0.03 628178.0 -1250.0 -0.01 -0.0288 -0.8824 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O01 compound treatment 667538.0 34400.0 0.25 755598.0 126000.0 0.96 0.8555 0.8634 2065847 ICCB6_000309 CCOC(=O)[C@@H]1[C@@H](C(=O)OC)[C@@]2([C@H](N1c3cccc(F)c3)c4ccccc4)C(=O)N(Cc5ccccc5)c6ccccc62 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O02 compound treatment 802610.0 169000.0 1.24 812344.0 183000.0 1.39 1.8588 0.9984 3176588 ICCB6_000310 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)NCc5ccc(Cl)c(Cl)c5)c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O03 compound treatment 712103.0 78900.0 0.58 798305.0 169000.0 1.28 1.3153 0.935 2065848 ICCB6_000311 Cc1ccc(cc1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O04 compound treatment 782356.0 149000.0 1.09 836452.0 207000.0 1.57 1.8835 0.984 3176589 ICCB6_000312 CON(C)C(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)N(C(=O)OCc5ccc(cc5)[N+](=O)[O-])c6ccc(C#CC7(O)CCCCCC7)cc64)C(C(OC2=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O05 compound treatment 819764.0 187000.0 1.36 810587.0 181000.0 1.38 1.9381 1.0 2065849 ICCB6_000313 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)CCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O06 compound treatment 705378.0 72200.0 0.53 767467.0 138000.0 1.05 1.1149 0.9496 2065850 ICCB6_000314 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(Br)cc4)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O07 compound treatment 686164.0 53000.0 0.39 875848.0 246000.0 1.87 1.5978 0.8358 2065851 ICCB6_000315 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O08 compound treatment 775656.0 142000.0 1.04 757676.0 128000.0 0.97 1.4257 0.9994 2065852 ICCB6_000316 COc1cc(C[C@@H]2[C@@H]3CC(CCC3=C)C(C)(C)N2N=Nc4ccc(cc4)[N+](=O)[O-])cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O09 compound treatment 784947.0 152000.0 1.11 955591.0 326000.0 2.48 2.5369 0.9344 2065853 ICCB6_000317 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccc(OC)c(OC)c3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O10 compound treatment 754503.0 121000.0 0.89 734447.0 105000.0 0.8 1.1916 0.9986 2065854 ICCB6_000318 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O11 compound treatment 714275.0 81100.0 0.59 701035.0 71600.0 0.54 0.8041 0.9991 2065855 ICCB6_000319 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O12 compound treatment 705731.0 72600.0 0.53 716398.0 87000.0 0.66 0.8424 0.9941 2065856 ICCB6_000320 CC(C)C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O13 compound treatment 642115.0 8950.0 0.07 649031.0 19600.0 0.15 0.1516 0.9319 1952450 ICCB6_000321 CCOC(=O)C(O)C(O)c1ccc(CO[Si](C(C)C)(C(C)C)c2ccccc2)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O14 compound treatment 655738.0 22600.0 0.17 685029.0 55600.0 0.42 0.4154 0.916 2065857 ICCB6_000322 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O15 compound treatment 796612.0 163000.0 1.2 647135.0 17700.0 0.13 0.9403 0.7817 1952761 ICCB6_000323 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O16 compound treatment 720589.0 87400.0 0.64 655191.0 25800.0 0.2 0.5905 0.8831 2065858 ICCB6_000324 C[C@@H]1[C@@H]2CC(CCC2=C)C(C)(C)N1N=Nc3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O17 compound treatment 229370.0 -404000.0 -2.95 160605.0 -469000.0 -3.56 -4.6065 -0.9957 1952837 ICCB6_000325 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O18 compound treatment 562449.0 -70700.0 -0.52 712325.0 82900.0 0.63 0.0796 0.0977 2065859 ICCB6_000326 CO[C@H]1O[C@@H]2COC(O[C@H]2[C@H](OC(=O)/C=C/C=C/C)[C@H]1OC(=O)/C=C/C=C/C)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O19 compound treatment 733853.0 101000.0 0.74 536786.0 -92600.0 -0.7 0.023 0.0226 1952633 ICCB6_000327 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O20 compound treatment 728593.0 95400.0 0.7 786294.0 157000.0 1.19 1.3361 0.9675 2065860 ICCB6_000328 CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COC(c2ccccc2)(c3ccccc3)c4ccccc4)O[C@H](CC=C)[C@H](O[Si](C)(C)C(C)(C)C)[C@H]1N=[N+]=[N-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O21 compound treatment 752953.0 120000.0 0.88 681927.0 52500.0 0.4 0.9014 0.9365 1952755 ICCB6_000329 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O22 compound treatment 758314.0 125000.0 0.92 691138.0 61700.0 0.47 0.9786 0.9517 2065861 ICCB6_000330 C[C@H]1[C@H](OC(=O)N1C(=O)[C@@H](CC=C)C(C)(C)C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O23 mock treatment 764324.0 131000.0 0.96 660120.0 30700.0 0.23 0.8431 0.8541 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 O24 mock treatment 673264.0 40100.0 0.29 654367.0 24900.0 0.19 0.3413 0.9776 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P01 compound treatment 637298.0 4130.0 0.03 792114.0 163000.0 1.24 0.8953 0.7242 2065862 ICCB6_000331 CC1(C)OCC2=C(CC(CCc3ccccc3)OC2CCc4ccccc4)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P02 compound treatment 650911.0 17700.0 0.13 767146.0 138000.0 1.05 0.8315 0.7888 2065863 ICCB6_000332 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(I)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P03 compound treatment 754852.0 122000.0 0.89 798567.0 169000.0 1.28 1.5378 0.9839 2065864 ICCB6_000333 C1CCC(CC1)c2c(cc(c3ccccc3)n2c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P04 compound treatment 678929.0 45800.0 0.33 643145.0 13700.0 0.1 0.3103 0.8853 2065865 ICCB6_000334 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P05 compound treatment 722520.0 89400.0 0.65 721762.0 92300.0 0.7 0.958 0.9994 2065866 ICCB6_000335 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)C(C)C)c3cc(OCCCO)ccc3N2C(=O)CN1C(=O)Cc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P06 compound treatment 785881.0 153000.0 1.12 869868.0 240000.0 1.83 2.0813 0.9721 2065867 ICCB6_000336 CCCCOc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P07 compound treatment 749886.0 117000.0 0.85 750458.0 121000.0 0.92 1.2537 0.9993 2065868 ICCB6_000337 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](C(C)C)N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P08 compound treatment 747461.0 114000.0 0.84 906415.0 277000.0 2.1 2.0789 0.9182 2065869 ICCB6_000338 C[C@H](Cc1ccccc1)N(C)CC#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P09 compound treatment 904528.0 271000.0 1.98 892570.0 263000.0 2.0 2.8168 1.0 2065870 ICCB6_000339 CCOC(=O)CC1[C@@H]2[C@@H](NC(=O)c3ccccc3)c4cc(OCCCO)ccc4N2C(=O)[C@H](Cc5ccccc5)N1C(=O)Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P10 compound treatment 918640.0 285000.0 2.09 759118.0 130000.0 0.99 2.1729 0.9413 2065871 ICCB6_000340 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P11 compound treatment 618881.0 -14300.0 -0.1 572064.0 -57400.0 -0.44 -0.382 -0.8525 2065872 ICCB6_000341 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P12 compound treatment 739886.0 107000.0 0.78 695042.0 65600.0 0.5 0.9043 0.9765 2065873 ICCB6_000342 CCOC(OCC)C#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P13 compound treatment 881693.0 249000.0 1.82 755804.0 126000.0 0.96 1.964 0.9555 2065874 ICCB6_000343 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P14 compound treatment 170667.0 -462000.0 -3.38 127848.0 -502000.0 -3.81 -5.086 -0.9982 2065875 ICCB6_000344 Brc1ccc2NC(=O)/C(=C/C(=O)OCC=C)/c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P15 compound treatment 771584.0 138000.0 1.01 629182.0 -249.0 0.0 0.7144 0.7058 1952804 ICCB6_000345 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P16 compound treatment 304869.0 -328000.0 -2.4 321163.0 -308000.0 -2.34 -3.3536 -0.9999 2065876 ICCB6_000346 CCOC(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P17 compound treatment 789579.0 156000.0 1.14 671644.0 42200.0 0.32 1.0356 0.8717 1952838 ICCB6_000347 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P18 compound treatment 361206.0 -272000.0 -1.99 260879.0 -369000.0 -2.8 -3.3861 -0.986 2065877 ICCB6_000348 O=C(/C=C\1/C(=O)Nc2ccccc12)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P19 compound treatment 671331.0 38200.0 0.28 661300.0 31900.0 0.24 0.3686 0.9975 1952634 ICCB6_000349 COC(=O)[C@H](C)NC(=O)CC[C@@H]1C[C@H](C[C@@]2(CCC[C@H](COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P20 compound treatment 494158.0 -139000.0 -1.02 514340.0 -115000.0 -0.87 -1.3371 -0.9972 2065878 ICCB6_000350 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(Br)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P21 compound treatment 817419.0 184000.0 1.35 754597.0 125000.0 0.95 1.6252 0.9854 1952770 ICCB6_000351 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P22 compound treatment 349699.0 -283000.0 -2.07 188568.0 -441000.0 -3.35 -3.834 -0.9734 2065879 ICCB6_000352 CON(C)C(=O)/C=C\1/C(=O)Nc2ccc(I)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P23 mock treatment 738147.0 105000.0 0.77 687610.0 58200.0 0.44 0.8554 0.9656 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.1463 P24 mock treatment 792934.0 160000.0 1.17 691332.0 61900.0 0.47 1.1587 0.92 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A01 mock treatment 577847.0 -65400.0 -0.48 579264.0 -47700.0 -0.36 -0.5943 -0.9906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A02 mock treatment 629750.0 -13500.0 -0.1 601418.0 -25500.0 -0.19 -0.2069 -0.9509 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A03 compound treatment 695984.0 52700.0 0.39 623196.0 -3750.0 -0.03 0.2526 0.6531 3000673 BCB01_000001 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A04 compound treatment 533045.0 -110000.0 -0.81 562230.0 -64700.0 -0.49 -0.9175 -0.9719 3000674 BCB01_000002 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A05 compound treatment 559748.0 -83500.0 -0.61 580238.0 -46700.0 -0.35 -0.6827 -0.9667 3000675 BCB01_000003 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A06 compound treatment 482703.0 -161000.0 -1.17 554831.0 -72100.0 -0.55 -1.2175 -0.9398 3000676 BCB01_000004 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A07 compound treatment 582046.0 -61200.0 -0.45 719535.0 92600.0 0.7 0.1809 0.217 3093034 BCB01_000005 COc1cc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A08 compound treatment 471928.0 -171000.0 -1.25 535776.0 -91200.0 -0.69 -1.3756 -0.9609 3000677 BCB01_000006 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A09 compound treatment 513890.0 -129000.0 -0.95 666783.0 39800.0 0.3 -0.4549 -0.458 3093035 BCB01_000007 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A10 compound treatment 483099.0 -160000.0 -1.17 556971.0 -70000.0 -0.53 -1.204 -0.9361 3000678 BCB01_000008 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A11 compound treatment 640231.0 -3010.0 -0.02 766887.0 140000.0 1.06 0.7362 0.6923 3093104 BCB01_000009 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A12 compound treatment 613773.0 -29500.0 -0.22 724856.0 97900.0 0.74 0.3736 0.4824 3093105 BCB01_000010 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A13 compound treatment 609706.0 -33500.0 -0.25 596448.0 -30500.0 -0.23 -0.3372 -0.9996 3000679 BCB01_000011 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A14 compound treatment 558933.0 -84300.0 -0.62 649408.0 22500.0 0.17 -0.3153 -0.4929 3093106 BCB01_000012 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A15 compound treatment 562289.0 -81000.0 -0.59 560136.0 -66800.0 -0.51 -0.7775 -0.9971 3093107 BCB01_000013 CCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A16 compound treatment 544135.0 -99100.0 -0.72 602342.0 -24600.0 -0.19 -0.6447 -0.8613 3000680 BCB01_000014 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A17 compound treatment 609006.0 -34200.0 -0.25 635574.0 8630.0 0.07 -0.1307 -0.505 3093108 BCB01_000015 COc1cc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A18 compound treatment 573798.0 -69400.0 -0.51 727153.0 100000.0 0.76 0.1792 0.1958 3093109 BCB01_000016 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A19 compound treatment 638815.0 -4430.0 -0.03 667726.0 40800.0 0.31 0.1962 0.6298 3000681 BCB01_000017 COc1cc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A20 compound treatment 592935.0 -50300.0 -0.37 604912.0 -22000.0 -0.17 -0.3785 -0.9365 3093110 BCB01_000018 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A21 compound treatment 566051.0 -77200.0 -0.56 602904.0 -24000.0 -0.18 -0.5283 -0.8904 3000682 BCB01_000019 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A22 compound treatment 580140.0 -63100.0 -0.46 568971.0 -58000.0 -0.44 -0.6377 -0.9997 3093111 BCB01_000020 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A23 mock treatment 620640.0 -22600.0 -0.17 542424.0 -84500.0 -0.64 -0.5709 -0.8611 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 A24 mock treatment 559364.0 -83900.0 -0.61 541789.0 -85200.0 -0.65 -0.8912 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B01 mock treatment 639745.0 -3500.0 -0.03 607965.0 -19000.0 -0.14 -0.12 -0.8197 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B02 mock treatment 612624.0 -30600.0 -0.22 584866.0 -42100.0 -0.32 -0.3844 -0.9848 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B03 compound treatment 554118.0 -89100.0 -0.65 658135.0 31200.0 0.24 -0.2933 -0.423 3093112 BCB01_000021 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B04 compound treatment 508906.0 -134000.0 -0.98 630598.0 3650.0 0.03 -0.675 -0.6869 3000683 BCB01_000022 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B05 compound treatment 607284.0 -36000.0 -0.26 632014.0 5070.0 0.04 -0.1587 -0.5972 3093113 BCB01_000023 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B06 compound treatment 510491.0 -133000.0 -0.97 614933.0 -12000.0 -0.09 -0.751 -0.7702 3093114 BCB01_000024 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B07 compound treatment 297466.0 -346000.0 -2.53 379525.0 -247000.0 -1.88 -3.1171 -0.9893 3000684 BCB01_000025 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B08 compound treatment 480478.0 -163000.0 -1.19 545271.0 -81700.0 -0.62 -1.2804 -0.9539 3093115 BCB01_000026 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B09 compound treatment 575958.0 -67300.0 -0.49 633251.0 6300.0 0.05 -0.3141 -0.6353 3093116 BCB01_000027 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B10 compound treatment 650499.0 7260.0 0.05 564607.0 -62300.0 -0.47 -0.2973 -0.6239 3000685 BCB01_000028 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B11 compound treatment 632275.0 -11000.0 -0.08 688350.0 61400.0 0.47 0.2731 0.5771 3093117 BCB01_000029 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4c(C)cc(C)cc4C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B12 compound treatment 258035.0 -385000.0 -2.82 274921.0 -352000.0 -2.67 -3.8829 -0.9997 3093118 BCB01_000030 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B13 compound treatment 610450.0 -32800.0 -0.24 627004.0 57.5 0.0 -0.1693 -0.7058 3000686 BCB01_000031 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B14 compound treatment 537737.0 -106000.0 -0.77 512033.0 -115000.0 -0.87 -1.1629 -0.9981 3093119 BCB01_000032 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B15 compound treatment 667423.0 24200.0 0.18 599741.0 -27200.0 -0.21 -0.0211 -0.0775 3093120 BCB01_000033 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(c4ccccc4)c5ccccc5)C(=O)N(C3=O)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B16 compound treatment 397118.0 -246000.0 -1.8 419627.0 -207000.0 -1.57 -2.3864 -0.9978 3000687 BCB01_000034 CCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B17 compound treatment 704291.0 61100.0 0.45 688250.0 61300.0 0.47 0.645 0.9998 3000688 BCB01_000035 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B18 compound treatment 325547.0 -318000.0 -2.32 281103.0 -346000.0 -2.63 -3.5006 -0.9981 3093121 BCB01_000036 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B19 compound treatment 653396.0 10200.0 0.07 624854.0 -2090.0 -0.02 0.0413 0.5435 3093122 BCB01_000037 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B20 compound treatment 251708.0 -392000.0 -2.86 339436.0 -288000.0 -2.18 -3.5691 -0.9911 3093123 BCB01_000038 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B21 compound treatment 627267.0 -16000.0 -0.12 556192.0 -70800.0 -0.54 -0.4627 -0.8411 3000689 BCB01_000039 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B22 compound treatment 401024.0 -242000.0 -1.77 419880.0 -207000.0 -1.57 -2.3648 -0.9982 3093124 BCB01_000040 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B23 mock treatment 607082.0 -36200.0 -0.26 718803.0 91900.0 0.7 0.3064 0.4107 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 B24 mock treatment 653948.0 10700.0 0.08 640543.0 13600.0 0.1 0.1284 0.9907 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C01 mock treatment 559411.0 -83800.0 -0.61 584844.0 -42100.0 -0.32 -0.6597 -0.954 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C02 mock treatment 554751.0 -88500.0 -0.65 558849.0 -68100.0 -0.52 -0.8234 -0.9938 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C03 compound treatment 580557.0 -62700.0 -0.46 664588.0 37600.0 0.29 -0.1219 -0.2257 3000690 BCB01_000041 COc1cc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C04 compound treatment 579141.0 -64100.0 -0.47 570685.0 -56300.0 -0.43 -0.6337 -0.9989 3093125 BCB01_000042 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C05 compound treatment 578229.0 -65000.0 -0.48 531613.0 -95300.0 -0.72 -0.8483 -0.9792 3093282 BCB01_000043 COc1cc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C06 compound treatment 472288.0 -171000.0 -1.25 575053.0 -51900.0 -0.39 -1.1628 -0.887 3000691 BCB01_000044 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C07 compound treatment 586962.0 -56300.0 -0.41 630298.0 3350.0 0.03 -0.273 -0.6621 3093194 BCB01_000045 COc1cc(NN2C3C(C=CC2C(O)C4CCC(CC4)C(=C)C)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C08 compound treatment 574589.0 -68700.0 -0.5 599878.0 -27100.0 -0.21 -0.5004 -0.9224 3093195 BCB01_000046 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C09 compound treatment 552947.0 -90300.0 -0.66 559910.0 -67000.0 -0.51 -0.827 -0.9918 3000692 BCB01_000047 COc1cc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C)C3=O)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C10 compound treatment 627380.0 -15900.0 -0.12 506192.0 -121000.0 -0.92 -0.7307 -0.7902 3093196 BCB01_000048 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C11 compound treatment 307260.0 -336000.0 -2.46 344149.0 -283000.0 -2.15 -3.2565 -0.9978 3093197 BCB01_000049 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3cc(OC)c(OC)c(OC)c3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C12 compound treatment 598723.0 -44500.0 -0.33 707634.0 80700.0 0.61 0.2032 0.2928 3000693 BCB01_000050 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C13 compound treatment 568308.0 -74900.0 -0.55 557332.0 -69600.0 -0.53 -0.7614 -0.9998 3093198 BCB01_000051 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C14 compound treatment 570607.0 -72600.0 -0.53 685251.0 58300.0 0.44 -0.0624 -0.0902 3000694 BCB01_000052 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C15 compound treatment 493580.0 -150000.0 -1.09 721085.0 94100.0 0.72 -0.2682 -0.2052 3093199 BCB01_000053 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C16 compound treatment 516687.0 -127000.0 -0.93 633468.0 6520.0 0.05 -0.6194 -0.6683 3093200 BCB01_000054 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C17 compound treatment 543527.0 -99700.0 -0.73 614846.0 -12100.0 -0.09 -0.5806 -0.79 3000695 BCB01_000055 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C18 compound treatment 530332.0 -113000.0 -0.83 664198.0 37300.0 0.28 -0.3838 -0.4397 3093201 BCB01_000056 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C19 compound treatment 632303.0 -10900.0 -0.08 564312.0 -62600.0 -0.48 -0.393 -0.8145 3093202 BCB01_000057 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C20 compound treatment 648748.0 5510.0 0.04 646465.0 19500.0 0.15 0.1333 0.8677 3000696 BCB01_000058 COc1ccc(cc1)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C21 compound treatment 585623.0 -57600.0 -0.42 664029.0 37100.0 0.28 -0.0987 -0.1948 3093203 BCB01_000059 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C22 compound treatment 631195.0 -12000.0 -0.09 610744.0 -16200.0 -0.12 -0.1493 -0.9865 3093204 BCB01_000060 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C23 mock treatment 597411.0 -45800.0 -0.34 671089.0 44100.0 0.34 1.0E-4 3.0E-4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 C24 mock treatment 571154.0 -72100.0 -0.53 598335.0 -28600.0 -0.22 -0.5265 -0.9233 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D01 mock treatment 548734.0 -94500.0 -0.69 588397.0 -38500.0 -0.29 -0.6958 -0.9269 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D02 mock treatment 649063.0 5820.0 0.04 595067.0 -31900.0 -0.24 -0.1411 -0.574 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D03 compound treatment 516451.0 -127000.0 -0.93 608747.0 -18200.0 -0.14 -0.7534 -0.8037 3000697 BCB01_000061 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccc(O)c4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D04 compound treatment 327651.0 -316000.0 -2.31 466331.0 -161000.0 -1.22 -2.4947 -0.9556 3093205 BCB01_000062 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D05 compound treatment 539031.0 -104000.0 -0.76 488294.0 -139000.0 -1.05 -1.2837 -0.9874 3093206 BCB01_000063 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)B(O)O)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D06 compound treatment 465494.0 -178000.0 -1.3 666502.0 39600.0 0.3 -0.7067 -0.5297 3000698 BCB01_000064 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D07 compound treatment 476611.0 -167000.0 -1.22 586679.0 -40300.0 -0.31 -1.078 -0.858 3093207 BCB01_000065 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cn(C(=O)C)c5ccccc45)C(=O)N(C3=O)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D08 compound treatment 584619.0 -58600.0 -0.43 558260.0 -68700.0 -0.52 -0.6721 -0.9952 3000792 BCB01_000066 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D09 compound treatment 486890.0 -156000.0 -1.14 585710.0 -41200.0 -0.31 -1.03 -0.8688 3000794 BCB01_000067 CC(C)c1ccc(NN2C3C(C=CC2C(O)C(C)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D10 compound treatment 377416.0 -266000.0 -1.94 369319.0 -258000.0 -1.96 -2.7585 -1.0 3000796 BCB01_000068 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D11 compound treatment 657071.0 13800.0 0.1 639181.0 12200.0 0.09 0.1372 0.9991 3000797 BCB01_000069 CC(C)c1ccc(NN2C3C(C=CC2C(O)CC(C)c4ccc(C)o4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D12 compound treatment 317991.0 -325000.0 -2.38 414870.0 -212000.0 -1.61 -2.8211 -0.982 3093208 BCB01_000070 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4c(F)cccc4Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D13 compound treatment 605982.0 -37300.0 -0.27 617184.0 -9760.0 -0.07 -0.2451 -0.868 3093209 BCB01_000071 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4cccs4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D14 compound treatment 376291.0 -267000.0 -1.95 487241.0 -140000.0 -1.06 -2.1309 -0.959 3000798 BCB01_000072 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D15 compound treatment 656318.0 13100.0 0.1 712359.0 85400.0 0.65 0.5264 0.8027 3093210 BCB01_000073 CC(C)c1ccc(NN2C3C(C=CC2C(O)Cc4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D16 compound treatment 541616.0 -102000.0 -0.74 446395.0 -181000.0 -1.37 -1.4954 -0.9586 3000800 BCB01_000074 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D17 compound treatment 636372.0 -6870.0 -0.05 594520.0 -32400.0 -0.25 -0.2097 -0.8341 3093211 BCB01_000075 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D18 compound treatment 361834.0 -281000.0 -2.06 586031.0 -40900.0 -0.31 -1.675 -0.8048 3000876 BCB01_000076 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c(C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D19 compound treatment 607659.0 -35600.0 -0.26 729621.0 103000.0 0.78 0.3675 0.447 3000877 BCB01_000077 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc5OCOc5c4)C(=O)N(C3=O)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D20 compound treatment 612950.0 -30300.0 -0.22 610488.0 -16500.0 -0.13 -0.245 -0.9634 3000878 BCB01_000078 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D21 compound treatment 713002.0 69800.0 0.51 590411.0 -36500.0 -0.28 0.1645 0.2832 3000880 BCB01_000079 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4=C[C@H]5C[C@@H](C4)C5(C)C)C(=O)N(C3=O)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D22 compound treatment 595016.0 -48200.0 -0.35 617576.0 -9370.0 -0.07 -0.2997 -0.833 3093212 BCB01_000080 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D23 mock treatment 598839.0 -44400.0 -0.32 672584.0 45600.0 0.35 0.0155 0.0327 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 D24 mock treatment 603226.0 -40000.0 -0.29 616127.0 -10800.0 -0.08 -0.265 -0.872 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E01 mock treatment 608965.0 -34300.0 -0.25 506909.0 -120000.0 -0.91 -0.8221 -0.8692 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E02 mock treatment 610432.0 -32800.0 -0.24 501246.0 -126000.0 -0.95 -0.8449 -0.8581 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E03 compound treatment 582055.0 -61200.0 -0.45 638394.0 11400.0 0.09 -0.2549 -0.5592 3000882 BCB01_000081 CN1C(=O)C2C=CC(C(O)C#Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E04 compound treatment 539044.0 -104000.0 -0.76 631090.0 4140.0 0.03 -0.5166 -0.6773 3093213 BCB01_000082 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E05 compound treatment 541639.0 -102000.0 -0.74 603462.0 -23500.0 -0.18 -0.6515 -0.8527 3093214 BCB01_000083 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E06 compound treatment 553375.0 -89900.0 -0.66 569409.0 -57500.0 -0.44 -0.7738 -0.9804 3000884 BCB01_000084 CN1C(=O)C2C=CC(C(O)C3CCC(CC3)C(=C)C)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E07 compound treatment 560557.0 -82700.0 -0.6 647871.0 20900.0 0.16 -0.3152 -0.5041 3093215 BCB01_000085 CN1C(=O)C2C=CC(C(O)c3ccco3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E08 compound treatment 663566.0 20300.0 0.15 557747.0 -69200.0 -0.53 -0.2666 -0.488 3093216 BCB01_000086 CCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E09 compound treatment 533248.0 -110000.0 -0.8 622094.0 -4850.0 -0.04 -0.5949 -0.7387 3000885 BCB01_000087 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E10 compound treatment 467815.0 -175000.0 -1.28 578020.0 -48900.0 -0.37 -1.17 -0.8759 3093283 BCB01_000088 CCCCCCCCCCC(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E11 compound treatment 505796.0 -137000.0 -1.01 502828.0 -124000.0 -0.94 -1.3775 -0.9995 3093284 BCB01_000089 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E12 compound treatment 602351.0 -40900.0 -0.3 559792.0 -67200.0 -0.51 -0.5722 -0.9676 3000886 BCB01_000090 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E13 compound treatment 570361.0 -72900.0 -0.53 582990.0 -44000.0 -0.33 -0.613 -0.9746 3093285 BCB01_000091 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E14 compound treatment 658860.0 15600.0 0.11 595893.0 -31100.0 -0.24 -0.086 -0.3283 3093286 BCB01_000092 COc1ccc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c5ccccc15 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E15 compound treatment 652705.0 9460.0 0.07 668131.0 41200.0 0.31 0.2702 0.8432 3000889 BCB01_000093 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E16 compound treatment 631947.0 -11300.0 -0.08 579238.0 -47700.0 -0.36 -0.3147 -0.8465 3093287 BCB01_000094 COc1cc(Br)cc(C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E17 compound treatment 588635.0 -54600.0 -0.4 629355.0 2410.0 0.02 -0.2694 -0.674 3093288 BCB01_000095 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E18 compound treatment 550205.0 -93000.0 -0.68 551267.0 -75700.0 -0.57 -0.8876 -0.9965 3000890 BCB01_000096 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3N5CCCCC5)C(=O)N(C)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E19 compound treatment 652117.0 8880.0 0.06 587885.0 -39100.0 -0.3 -0.1639 -0.5397 3093289 BCB01_000097 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E20 compound treatment 684117.0 40900.0 0.3 574565.0 -52400.0 -0.4 -0.07 -0.1406 3093290 BCB01_000098 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2N4CCCCC4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E21 compound treatment 618393.0 -24800.0 -0.18 605564.0 -21400.0 -0.16 -0.2433 -0.9984 3000891 BCB01_000099 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E22 compound treatment 692049.0 48800.0 0.36 672923.0 46000.0 0.35 0.4994 0.9999 3093291 BCB01_000100 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E23 mock treatment 672358.0 29100.0 0.21 639108.0 12200.0 0.09 0.2159 0.9301 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 E24 mock treatment 705755.0 62500.0 0.46 657882.0 30900.0 0.24 0.4895 0.9522 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F01 mock treatment 644063.0 823.0 0.01 593111.0 -33800.0 -0.26 -0.1775 -0.6904 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F02 mock treatment 601104.0 -42100.0 -0.31 569900.0 -57000.0 -0.43 -0.5243 -0.986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F03 compound treatment 531968.0 -111000.0 -0.81 554634.0 -72300.0 -0.55 -0.9638 -0.9817 3093292 BCB01_000101 CC(C)c1ccc(NN2C3C(C=CC2C(O)/C=C(\C)/CCC=C(C)C)C(=O)N(C3=O)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F04 compound treatment 327487.0 -316000.0 -2.31 428966.0 -198000.0 -1.5 -2.6963 -0.9784 3000892 BCB01_000102 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F05 compound treatment 526268.0 -117000.0 -0.86 556490.0 -70500.0 -0.54 -0.9834 -0.9745 3093293 BCB01_000103 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F06 compound treatment 360618.0 -283000.0 -2.07 385066.0 -242000.0 -1.84 -2.7608 -0.9983 3000894 BCB01_000104 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F07 compound treatment 512085.0 -131000.0 -0.96 514485.0 -112000.0 -0.85 -1.2823 -0.9983 3093294 BCB01_000105 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F08 compound treatment 521389.0 -122000.0 -0.89 532485.0 -94500.0 -0.72 -1.1375 -0.9942 3093295 BCB01_000106 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F09 compound treatment 489469.0 -154000.0 -1.12 610403.0 -16500.0 -0.13 -0.884 -0.7813 3000896 BCB01_000107 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F10 compound treatment 534129.0 -109000.0 -0.8 592219.0 -34700.0 -0.26 -0.7508 -0.8933 3093296 BCB01_000108 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F11 compound treatment 570001.0 -73200.0 -0.54 542704.0 -84200.0 -0.64 -0.8313 -0.9961 3093297 BCB01_000109 CN1C(=O)C2C=CC(C(O)c3ccc(cc3)C(=O)C)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F12 compound treatment 572189.0 -71100.0 -0.52 620689.0 -6260.0 -0.05 -0.401 -0.7686 3000898 BCB01_000110 CC(C)C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F13 compound treatment 133849.0 -509000.0 -3.73 168914.0 -458000.0 -3.48 -5.0946 -0.9994 3000979 BCB01_000111 CCCCCCCCCCC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F14 compound treatment 496352.0 -147000.0 -1.07 558157.0 -68800.0 -0.52 -1.1291 -0.9452 3000980 BCB01_000112 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccc(O)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F15 compound treatment 674278.0 31000.0 0.23 609036.0 -17900.0 -0.14 0.0643 0.2429 3000981 BCB01_000113 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F16 compound treatment 582081.0 -61200.0 -0.45 463665.0 -163000.0 -1.24 -1.1934 -0.905 3000982 BCB01_000114 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F17 compound treatment 478686.0 -165000.0 -1.2 415587.0 -211000.0 -1.61 -1.9863 -0.9899 3000984 BCB01_000115 COc1ccc(C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O)c4ccccc14 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F18 compound treatment 583748.0 -59500.0 -0.44 566703.0 -60200.0 -0.46 -0.6313 -0.9997 3093298 BCB01_000116 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F19 compound treatment 666379.0 23100.0 0.17 651189.0 24200.0 0.18 0.2499 0.9991 3093299 BCB01_000117 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F20 compound treatment 650173.0 6930.0 0.05 705810.0 78900.0 0.6 0.4595 0.7642 3000987 BCB01_000118 CC(=O)N1CC(C(O)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O)c5ccccc15 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F21 compound treatment 637743.0 -5500.0 -0.04 687029.0 60100.0 0.46 0.2943 0.6423 3093300 BCB01_000119 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F22 compound treatment 604172.0 -39100.0 -0.29 633905.0 6960.0 0.05 -0.1646 -0.5667 3093301 BCB01_000120 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F23 mock treatment 598227.0 -45000.0 -0.33 701956.0 75000.0 0.57 0.1702 0.2586 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 F24 mock treatment 667062.0 23800.0 0.17 640873.0 13900.0 0.11 0.198 0.9714 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G01 mock treatment 607204.0 -36000.0 -0.26 578915.0 -48000.0 -0.36 -0.4444 -0.9872 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G02 mock treatment 520104.0 -123000.0 -0.9 526901.0 -100000.0 -0.76 -1.1742 -0.9964 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G03 compound treatment 545210.0 -98000.0 -0.72 576064.0 -50900.0 -0.39 -0.7803 -0.958 3000990 BCB01_000121 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G04 compound treatment 532695.0 -111000.0 -0.81 458855.0 -168000.0 -1.28 -1.4746 -0.9757 3093302 BCB01_000122 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G05 compound treatment 519499.0 -124000.0 -0.9 525750.0 -101000.0 -0.77 -1.1835 -0.9967 3093303 BCB01_000123 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G06 compound treatment 545174.0 -98100.0 -0.72 560775.0 -66200.0 -0.5 -0.8626 -0.9849 3000991 BCB01_000124 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G07 compound treatment 520455.0 -123000.0 -0.9 560778.0 -66200.0 -0.5 -0.9904 -0.9624 3093304 BCB01_000125 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G08 compound treatment 536893.0 -106000.0 -0.78 547151.0 -79800.0 -0.61 -0.9786 -0.9924 3000992 BCB01_000126 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G09 compound treatment 548563.0 -94700.0 -0.69 569572.0 -57400.0 -0.44 -0.7978 -0.9751 3093373 BCB01_000127 CN1C(=O)C2C=CC(C(O)c3c(C)cc(C)cc3C)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G10 compound treatment 610909.0 -32300.0 -0.24 586974.0 -40000.0 -0.3 -0.3819 -0.9923 3093374 BCB01_000128 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(C2C1=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G11 compound treatment 575964.0 -67300.0 -0.49 638871.0 11900.0 0.09 -0.2838 -0.5674 3000993 BCB01_000129 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G12 compound treatment 576186.0 -67100.0 -0.49 547068.0 -79900.0 -0.61 -0.7758 -0.9944 3093375 BCB01_000130 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(C2C1=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G13 compound treatment 572004.0 -71200.0 -0.52 615163.0 -11800.0 -0.09 -0.4317 -0.8166 3093376 BCB01_000131 CN1C(=O)C2C=CC(C(O)/C=C/c3ccc(cc3)[N+](=O)[O-])N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G14 compound treatment 561811.0 -81400.0 -0.6 548448.0 -78500.0 -0.6 -0.8428 -1.0 3000994 BCB01_000132 C/C=C/C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G15 compound treatment 628234.0 -15000.0 -0.11 628765.0 1820.0 0.01 -0.0678 -0.6133 3093377 BCB01_000133 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(Nc5ccccc5)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G16 compound treatment 580274.0 -63000.0 -0.46 594182.0 -32800.0 -0.25 -0.5016 -0.9583 3000995 BCB01_000134 CCC(CC)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G17 compound treatment 578675.0 -64600.0 -0.47 675739.0 48800.0 0.37 -0.0718 -0.1196 3093378 BCB01_000135 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G18 compound treatment 589365.0 -53900.0 -0.39 621821.0 -5130.0 -0.04 -0.3061 -0.7732 3000996 BCB01_000136 CC(C)C(O)C1C=CC2C(N1N3CCCCC3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G19 compound treatment 693739.0 50500.0 0.37 689446.0 62500.0 0.47 0.5969 0.9923 3093379 BCB01_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G20 compound treatment 589652.0 -53600.0 -0.39 675416.0 48500.0 0.37 -0.0167 -0.0311 3093380 BCB01_000138 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G21 compound treatment 722211.0 79000.0 0.58 560517.0 -66400.0 -0.5 0.0515 0.0672 3000997 BCB01_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G22 compound treatment 595018.0 -48200.0 -0.35 536265.0 -90700.0 -0.69 -0.7365 -0.9516 3093381 BCB01_000140 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G23 mock treatment 719172.0 75900.0 0.56 579656.0 -47300.0 -0.36 0.1386 0.2096 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 G24 mock treatment 628092.0 -15100.0 -0.11 615524.0 -11400.0 -0.09 -0.1397 -0.9927 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H01 mock treatment 611756.0 -31500.0 -0.23 520702.0 -106000.0 -0.81 -0.7335 -0.874 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H02 mock treatment 537898.0 -105000.0 -0.77 487416.0 -140000.0 -1.06 -1.2943 -0.9877 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H03 compound treatment 568310.0 -74900.0 -0.55 524397.0 -103000.0 -0.78 -0.9383 -0.9852 3000998 BCB01_000141 CN1C(=O)C2C=CC(C(O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H04 compound treatment 452536.0 -191000.0 -1.39 519177.0 -108000.0 -0.82 -1.5651 -0.9678 3093382 BCB01_000142 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H05 compound treatment 562855.0 -80400.0 -0.59 614666.0 -12300.0 -0.09 -0.4817 -0.8092 3093383 BCB01_000143 CN1C(=O)C2C=CC(C(O)c3c(F)cccc3Cl)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H06 compound treatment 503234.0 -140000.0 -1.02 626635.0 -312.0 0.0 -0.7257 -0.7087 3000999 BCB01_000144 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(C#N)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H07 compound treatment 506494.0 -137000.0 -1.0 631909.0 4960.0 0.04 -0.6805 -0.68 3093384 BCB01_000145 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H08 compound treatment 489044.0 -154000.0 -1.13 548721.0 -78200.0 -0.59 -1.2176 -0.9552 3093385 BCB01_000146 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H09 compound treatment 581050.0 -62200.0 -0.45 556968.0 -70000.0 -0.53 -0.6975 -0.997 3001000 BCB01_000147 CN1C(=O)C2C=CC(C(O)C(c3ccccc3)c4ccccc4)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H10 compound treatment 460773.0 -182000.0 -1.33 467971.0 -159000.0 -1.21 -1.7975 -0.9988 3001068 BCB01_000148 CC1(C)[C@H]2CC1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(Cl)cc5Cl)C(=O)NC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H11 compound treatment 613349.0 -29900.0 -0.22 551583.0 -75400.0 -0.57 -0.5594 -0.9128 3001069 BCB01_000149 CN1C(=O)C2C=CC(C(O)c3cccc4ccccc34)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H12 compound treatment 550484.0 -92800.0 -0.68 606869.0 -20100.0 -0.15 -0.5875 -0.845 3001070 BCB01_000150 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(Cl)cc4Cl)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H13 compound treatment 569999.0 -73200.0 -0.54 624773.0 -2170.0 -0.02 -0.3904 -0.7286 3001072 BCB01_000151 C/C=C/C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H14 compound treatment 438292.0 -205000.0 -1.5 522960.0 -104000.0 -0.79 -1.6184 -0.9552 3093386 BCB01_000152 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H15 compound treatment 624939.0 -18300.0 -0.13 528772.0 -98200.0 -0.75 -0.622 -0.8209 3001073 BCB01_000153 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(NC(=O)OC(C)(C)C)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H16 compound treatment 604492.0 -38700.0 -0.28 635090.0 8140.0 0.06 -0.1566 -0.54 3093387 BCB01_000154 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H17 compound treatment 590654.0 -52600.0 -0.38 682883.0 55900.0 0.42 0.0285 0.0498 3093388 BCB01_000155 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2NC(=O)OC(C)(C)C)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H18 compound treatment 673105.0 29900.0 0.22 571206.0 -55700.0 -0.42 -0.145 -0.3043 3001076 BCB01_000156 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(I)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H19 compound treatment 624459.0 -18800.0 -0.14 546894.0 -80100.0 -0.61 -0.5271 -0.8455 3093389 BCB01_000157 CC(C(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H20 compound treatment 616048.0 -27200.0 -0.2 586736.0 -40200.0 -0.31 -0.3566 -0.9784 3093390 BCB01_000158 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H21 compound treatment 740073.0 96800.0 0.71 704535.0 77600.0 0.59 0.9175 0.9958 3001078 BCB01_000159 CC(CC(O)C1C=CC2C(N1NC(=O)OC(C)(C)C)C(=O)N(C)C2=O)c3ccc(C)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H22 compound treatment 552453.0 -90800.0 -0.66 629908.0 2960.0 0.02 -0.4536 -0.6828 3093391 BCB01_000160 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H23 mock treatment 714558.0 71300.0 0.52 590799.0 -36100.0 -0.27 0.1746 0.2963 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 H24 mock treatment 640918.0 -2320.0 -0.02 646522.0 19600.0 0.15 0.0931 0.6223 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I01 mock treatment 595171.0 -48100.0 -0.35 582694.0 -44300.0 -0.34 -0.4863 -0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I02 mock treatment 582603.0 -60600.0 -0.44 490290.0 -137000.0 -1.04 -1.0476 -0.928 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I03 compound treatment 647372.0 4130.0 0.03 560943.0 -66000.0 -0.5 -0.3332 -0.6633 3001079 BCB01_000161 CN1C(=O)C2C=CC(C(O)c3cccc(O)c3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I04 compound treatment 519549.0 -124000.0 -0.9 577534.0 -49400.0 -0.38 -0.9051 -0.9241 3093392 BCB01_000162 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I05 compound treatment 546048.0 -97200.0 -0.71 597459.0 -29500.0 -0.22 -0.661 -0.887 3093393 BCB01_000163 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I06 compound treatment 609984.0 -33300.0 -0.24 602585.0 -24400.0 -0.19 -0.3028 -0.9909 3001081 BCB01_000164 CN1C(=O)C2C=CC(C(O)C3=CC[C@H](CC3)C(=C)C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I07 compound treatment 560098.0 -83100.0 -0.61 557377.0 -69600.0 -0.53 -0.8036 -0.9976 3093394 BCB01_000165 CN1C(=O)C2C=CC(C(O)c3cn(C(=O)C)c4ccccc34)N(Nc5ccccc5)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I08 compound treatment 480628.0 -163000.0 -1.19 560725.0 -66200.0 -0.5 -1.1966 -0.9267 3093395 BCB01_000166 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I09 compound treatment 618670.0 -24600.0 -0.18 614325.0 -12600.0 -0.1 -0.1949 -0.9567 3001082 BCB01_000167 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I10 compound treatment 666166.0 22900.0 0.17 635835.0 8890.0 0.07 0.1663 0.9201 3093464 BCB01_000168 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I11 compound treatment 754131.0 111000.0 0.81 587191.0 -39800.0 -0.3 0.3599 0.4159 3001083 BCB01_000169 CC(C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I12 compound treatment 598666.0 -44600.0 -0.33 543623.0 -83300.0 -0.63 -0.6781 -0.9524 3093465 BCB01_000170 CN1C(=O)C2C=CC(C(O)c3cccn3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I13 compound treatment 716640.0 73400.0 0.54 620535.0 -6410.0 -0.05 0.3451 0.6403 3093466 BCB01_000171 CC(CC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C)C2=O)c4ccc(C)o4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I14 compound treatment 697405.0 54200.0 0.4 731033.0 104000.0 0.79 0.8392 0.9489 3001084 BCB01_000172 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I15 compound treatment 545550.0 -97700.0 -0.71 639728.0 12800.0 0.1 -0.4365 -0.6054 3093467 BCB01_000173 CN1C(=O)C2C=CC(C(O)c3cccs3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I16 compound treatment 732029.0 88800.0 0.65 597761.0 -29200.0 -0.22 0.3024 0.4407 3093468 BCB01_000174 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I17 compound treatment 702673.0 59400.0 0.43 578789.0 -48200.0 -0.37 0.0486 0.0856 3001085 BCB01_000175 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I18 compound treatment 665499.0 22300.0 0.16 656680.0 29700.0 0.23 0.2748 0.9871 3093469 BCB01_000176 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3[N+](=O)[O-])[N+](=O)[O-])C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I19 compound treatment 641192.0 -2050.0 -0.01 615364.0 -11600.0 -0.09 -0.0728 -0.8157 3001086 BCB01_000177 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccccc5)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I20 compound treatment 707475.0 64200.0 0.47 646341.0 19400.0 0.15 0.4363 0.8863 3093470 BCB01_000178 CN1C(=O)C2C=CC(C(O)C3=C[C@H]4C[C@@H](C3)C4(C)C)N(Nc5ccc(cc5[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I21 compound treatment 729530.0 86300.0 0.63 761813.0 135000.0 1.02 1.1707 0.9729 3001087 BCB01_000179 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I22 compound treatment 576583.0 -66700.0 -0.49 536159.0 -90800.0 -0.69 -0.8324 -0.9856 3093471 BCB01_000180 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccc(cc4[N+](=O)[O-])[N+](=O)[O-])C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I23 mock treatment 639773.0 -3470.0 -0.03 695790.0 68800.0 0.52 0.3519 0.672 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 I24 mock treatment 703911.0 60700.0 0.44 687559.0 60600.0 0.46 0.6393 0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J01 mock treatment 588767.0 -54500.0 -0.4 511498.0 -115000.0 -0.88 -0.9018 -0.9362 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J02 mock treatment 630350.0 -12900.0 -0.09 652682.0 25700.0 0.2 0.0716 0.3298 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J03 compound treatment 671976.0 28700.0 0.21 639453.0 12500.0 0.1 0.2158 0.9356 3093472 BCB01_000181 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J04 compound treatment 659163.0 15900.0 0.12 550101.0 -76800.0 -0.58 -0.3305 -0.5551 3001088 BCB01_000182 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J05 compound treatment 635195.0 -8050.0 -0.06 639415.0 12500.0 0.09 0.0254 0.2276 3093473 BCB01_000183 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J06 compound treatment 479293.0 -164000.0 -1.2 540375.0 -86600.0 -0.66 -1.3128 -0.96 3093474 BCB01_000184 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J07 compound treatment 537289.0 -106000.0 -0.77 666639.0 39700.0 0.3 -0.3347 -0.4025 3001089 BCB01_000185 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J08 compound treatment 565574.0 -77700.0 -0.57 611547.0 -15400.0 -0.12 -0.4843 -0.8352 3001153 BCB01_000186 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J09 compound treatment 281755.0 -361000.0 -2.64 350113.0 -277000.0 -2.1 -3.3564 -0.9936 3001154 BCB01_000187 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J10 compound treatment 554514.0 -88700.0 -0.65 542253.0 -84700.0 -0.64 -0.9138 -1.0 3001156 BCB01_000188 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J11 compound treatment 643557.0 317.0 0.0 575958.0 -51000.0 -0.39 -0.2723 -0.7029 3001157 BCB01_000189 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J12 compound treatment 631884.0 -11400.0 -0.08 614639.0 -12300.0 -0.09 -0.1248 -0.9983 3093475 BCB01_000190 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J13 compound treatment 670157.0 26900.0 0.2 512210.0 -115000.0 -0.87 -0.4771 -0.534 3093476 BCB01_000191 CC(=O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J14 compound treatment 782182.0 139000.0 1.02 713412.0 86500.0 0.66 1.183 0.9777 3001159 BCB01_000192 CCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J15 compound treatment 743450.0 100000.0 0.73 641320.0 14400.0 0.11 0.5954 0.8036 3093477 BCB01_000193 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J16 compound treatment 201495.0 -442000.0 -3.23 292190.0 -335000.0 -2.54 -4.0826 -0.993 3001160 BCB01_000194 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J17 compound treatment 600117.0 -43100.0 -0.32 699386.0 72400.0 0.55 0.1661 0.2619 3093478 BCB01_000195 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J18 compound treatment 656073.0 12800.0 0.09 692208.0 65300.0 0.5 0.4169 0.8263 3093479 BCB01_000196 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J19 compound treatment 762981.0 120000.0 0.88 745966.0 119000.0 0.9 1.2585 0.9999 3001161 BCB01_000197 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J20 compound treatment 732398.0 89200.0 0.65 612595.0 -14400.0 -0.11 0.384 0.5808 3093480 BCB01_000198 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J21 compound treatment 797950.0 155000.0 1.13 701881.0 74900.0 0.57 1.2026 0.9495 3093481 BCB01_000199 CCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J22 compound treatment 659731.0 16500.0 0.12 652785.0 25800.0 0.2 0.2241 0.9726 3001163 BCB01_000200 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J23 mock treatment 761011.0 118000.0 0.86 772543.0 146000.0 1.11 1.3911 0.9923 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 J24 mock treatment 711705.0 68500.0 0.5 664902.0 38000.0 0.29 0.5579 0.9656 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K01 mock treatment 659161.0 15900.0 0.12 625418.0 -1530.0 -0.01 0.0741 0.6334 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K02 mock treatment 683674.0 40400.0 0.3 574045.0 -52900.0 -0.4 -0.0751 -0.1505 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K03 compound treatment 621443.0 -21800.0 -0.16 561453.0 -65500.0 -0.5 -0.4645 -0.8891 3093482 BCB01_000201 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(Nc4ccccc4)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K04 compound treatment 638196.0 -5040.0 -0.04 562422.0 -64500.0 -0.49 -0.3727 -0.7582 3001164 BCB01_000202 CN1C(=O)C2C=CC(C(O)c3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K05 compound treatment 465909.0 -177000.0 -1.3 546094.0 -80900.0 -0.61 -1.3513 -0.9417 3093483 BCB01_000203 CN1C(=O)C2C=CC(C(O)/C=C(\C)/CCC=C(C)C)N(Nc3ccccc3)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K06 compound treatment 670624.0 27400.0 0.2 590945.0 -36000.0 -0.27 -0.0518 -0.1528 3093484 BCB01_000204 CN1C(=O)C2C=CC(C(O)c3ccc(I)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K07 compound treatment 771554.0 128000.0 0.94 538831.0 -88100.0 -0.67 0.1902 0.165 3000112 BCB01_000205 CN1C(=O)C2C=CC(C(O)C(C)(C)C)N(Nc3ccccc3)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K08 compound treatment 666383.0 23100.0 0.17 629210.0 2260.0 0.02 0.1318 0.775 3000114 BCB01_000206 COc1ccc(cc1)C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K09 compound treatment 685698.0 42500.0 0.31 641323.0 14400.0 0.11 0.2968 0.9017 3000115 BCB01_000207 CCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K10 compound treatment 679090.0 35800.0 0.26 620176.0 -6770.0 -0.05 0.149 0.5578 3000116 BCB01_000208 CN1C(=O)C2C=CC(C(O)C3CCCCC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K11 compound treatment 666933.0 23700.0 0.17 622776.0 -4170.0 -0.03 0.1001 0.5684 3000118 BCB01_000209 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(I)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K12 compound treatment 784983.0 142000.0 1.04 643386.0 16400.0 0.12 0.8213 0.7866 3093485 BCB01_000210 CCCCC(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K13 compound treatment 684426.0 41200.0 0.3 728941.0 102000.0 0.77 0.7609 0.9153 3093645 BCB01_000211 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K14 compound treatment 672271.0 29000.0 0.21 627436.0 489.0 0.0 0.1528 0.7194 3000120 BCB01_000212 CN1C(=O)C2C=CC(C(O)c3ccc(F)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K15 compound treatment 668600.0 25400.0 0.19 640440.0 13500.0 0.1 0.2036 0.9609 3093555 BCB01_000213 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K16 compound treatment 763390.0 120000.0 0.88 686910.0 60000.0 0.46 0.9434 0.9532 3093556 BCB01_000214 COc1ccc(C(O)C2C=CC3C(N2N(c4ccccc4)c5ccccc5)C(=O)N(C)C3=O)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K17 compound treatment 610382.0 -32900.0 -0.24 594859.0 -32100.0 -0.24 -0.3423 -1.0 3000122 BCB01_000215 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K18 compound treatment 643900.0 660.0 0.0 606200.0 -20700.0 -0.16 -0.108 -0.6851 3093557 BCB01_000216 CN1C(=O)C2C=CC(C(O)c3ccccn3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K19 compound treatment 587198.0 -56000.0 -0.41 611353.0 -15600.0 -0.12 -0.3736 -0.8756 3000123 BCB01_000217 OC(C#Cc1ccccc1)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K20 compound treatment 655575.0 12300.0 0.09 687872.0 60900.0 0.46 0.3911 0.8293 3093558 BCB01_000218 CN1C(=O)C2C=CC(C(O)c3ccc(s3)c4ccccc4)N(C2C1=O)N(c5ccccc5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K21 compound treatment 726330.0 83100.0 0.61 763463.0 137000.0 1.04 1.163 0.9676 3093559 BCB01_000219 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K22 compound treatment 671111.0 27900.0 0.2 722012.0 95100.0 0.72 0.6548 0.8726 3000124 BCB01_000220 CN1C(=O)C2C=CC(C(O)c3ccccc3C)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K23 mock treatment 661165.0 17900.0 0.13 686897.0 60000.0 0.46 0.4147 0.8751 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 K24 mock treatment 620471.0 -22800.0 -0.17 704804.0 77900.0 0.59 0.3005 0.489 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L01 mock treatment 554820.0 -88400.0 -0.65 658079.0 31100.0 0.24 -0.29 -0.4212 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L02 mock treatment 653088.0 9850.0 0.07 629358.0 2410.0 0.02 0.0639 0.8596 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L03 compound treatment 207553.0 -436000.0 -3.19 133390.0 -494000.0 -3.75 -4.9043 -0.9967 3093560 BCB01_000221 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L04 compound treatment 602468.0 -40800.0 -0.3 707450.0 80500.0 0.61 0.2216 0.3257 3093561 BCB01_000222 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L05 compound treatment 636374.0 -6870.0 -0.05 672892.0 45900.0 0.35 0.2113 0.5992 3000127 BCB01_000223 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L06 compound treatment 494361.0 -149000.0 -1.09 676065.0 49100.0 0.37 -0.506 -0.4397 3093562 BCB01_000224 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L07 compound treatment 726945.0 83700.0 0.61 669223.0 42300.0 0.32 0.6599 0.9547 3093563 BCB01_000225 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L08 compound treatment 558713.0 -84500.0 -0.62 677602.0 50700.0 0.38 -0.165 -0.2266 3000128 BCB01_000226 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L09 compound treatment 614754.0 -28500.0 -0.21 604527.0 -22400.0 -0.17 -0.2677 -0.995 3093564 BCB01_000227 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L10 compound treatment 654818.0 11600.0 0.08 616502.0 -10400.0 -0.08 0.0038 0.0325 3000129 BCB01_000228 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4c(F)cccc4Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L11 compound treatment 756636.0 113000.0 0.83 657949.0 31000.0 0.24 0.7529 0.8734 3093565 BCB01_000229 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L12 compound treatment 645559.0 2320.0 0.02 524635.0 -102000.0 -0.78 -0.5376 -0.6915 3093566 BCB01_000230 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(s4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L13 compound treatment 675842.0 32600.0 0.24 644761.0 17800.0 0.14 0.2643 0.964 3000131 BCB01_000231 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L14 compound treatment 367421.0 -276000.0 -2.02 355521.0 -271000.0 -2.06 -2.8843 -0.9999 3093567 BCB01_000232 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L15 compound treatment 512008.0 -131000.0 -0.96 526831.0 -100000.0 -0.76 -1.2164 -0.9934 3093568 BCB01_000233 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L16 compound treatment 634350.0 -8890.0 -0.07 702265.0 75300.0 0.57 0.3586 0.6228 3000133 BCB01_000234 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c(C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L17 compound treatment 677426.0 34200.0 0.25 612140.0 -14800.0 -0.11 0.0972 0.3547 3093569 BCB01_000235 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L18 compound treatment 597237.0 -46000.0 -0.34 517947.0 -109000.0 -0.83 -0.8234 -0.9213 3000205 BCB01_000236 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L19 compound treatment 731376.0 88100.0 0.64 789201.0 162000.0 1.23 1.3274 0.9543 3000206 BCB01_000237 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L20 compound treatment 696304.0 53100.0 0.39 636192.0 9250.0 0.07 0.3241 0.8217 3000207 BCB01_000238 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L21 compound treatment 865612.0 222000.0 1.63 791192.0 164000.0 1.25 2.0322 0.9914 3000208 BCB01_000239 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L22 compound treatment 672486.0 29200.0 0.21 711497.0 84600.0 0.64 0.6054 0.8943 3093570 BCB01_000240 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccn5)C(=O)NC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L23 mock treatment 709203.0 66000.0 0.48 660257.0 33300.0 0.25 0.52 0.9547 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 L24 mock treatment 797587.0 154000.0 1.13 624855.0 -2090.0 -0.02 0.7869 0.6971 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M01 mock treatment 699739.0 56500.0 0.41 655093.0 28100.0 0.21 0.4434 0.953 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M02 mock treatment 629430.0 -13800.0 -0.1 596101.0 -30800.0 -0.23 -0.2371 -0.9292 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M03 compound treatment 719714.0 76500.0 0.56 641470.0 14500.0 0.11 0.4735 0.8306 3000209 BCB01_000241 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccco5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M04 compound treatment 532952.0 -110000.0 -0.81 553062.0 -73900.0 -0.56 -0.9672 -0.9843 3093571 BCB01_000242 C/C=C/C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M05 compound treatment 589648.0 -53600.0 -0.39 609542.0 -17400.0 -0.13 -0.3706 -0.896 3093572 BCB01_000243 CCCCC(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M06 compound treatment 706585.0 63300.0 0.46 694237.0 67300.0 0.51 0.689 0.9988 3000211 BCB01_000244 CC(C)C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M07 compound treatment 576975.0 -66300.0 -0.48 687750.0 60800.0 0.46 -0.016 -0.024 3093573 BCB01_000245 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M08 compound treatment 589792.0 -53400.0 -0.39 701672.0 74700.0 0.57 0.125 0.1814 3093574 BCB01_000246 CN1C(=O)C2C=CC(C(O)C3CCC=CC3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M09 compound treatment 731096.0 87900.0 0.64 521205.0 -106000.0 -0.8 -0.1137 -0.1105 3000213 BCB01_000247 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M10 compound treatment 627044.0 -16200.0 -0.12 538029.0 -88900.0 -0.68 -0.5614 -0.8186 3093575 BCB01_000248 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M11 compound treatment 702710.0 59500.0 0.43 645513.0 18600.0 0.14 0.4073 0.8908 3000215 BCB01_000249 COc1ccc(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M12 compound treatment 745076.0 102000.0 0.74 700040.0 73100.0 0.56 0.9192 0.9895 3093576 BCB01_000250 CC(C(O)C1C=CC2C(N1N(c3ccccc3)c4ccccc4)C(=O)N(C)C2=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M13 compound treatment 681952.0 38700.0 0.28 607108.0 -19800.0 -0.15 0.0936 0.2919 3093646 BCB01_000251 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M14 compound treatment 790773.0 148000.0 1.08 566900.0 -60000.0 -0.46 0.4404 0.3759 3000219 BCB01_000252 CN1C(=O)C2C=CC(C(O)c3cccs3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M15 compound treatment 774806.0 132000.0 0.96 740337.0 113000.0 0.86 1.2895 0.9985 3093647 BCB01_000253 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M16 compound treatment 675962.0 32700.0 0.24 846335.0 219000.0 1.67 1.3477 0.8004 3000221 BCB01_000254 CN1C(=O)C2C=CC(C(O)Cc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M17 compound treatment 645423.0 2180.0 0.02 735270.0 108000.0 0.82 0.5932 0.7207 3093648 BCB01_000255 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M18 compound treatment 811630.0 168000.0 1.23 720688.0 93700.0 0.71 1.3743 0.9661 3093649 BCB01_000256 CN1C(=O)C2C=CC(C(O)c3ccc(Br)cc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M19 compound treatment 684144.0 40900.0 0.3 772241.0 145000.0 1.1 0.992 0.8674 3000223 BCB01_000257 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M20 compound treatment 685728.0 42500.0 0.31 714192.0 87200.0 0.66 0.6884 0.9404 3093650 BCB01_000258 CN1C(=O)C2C=CC(C(O)COCc3ccccc3)N(C2C1=O)N(c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M21 compound treatment 691608.0 48400.0 0.35 703667.0 76700.0 0.58 0.6622 0.9714 3093651 BCB01_000259 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M22 compound treatment 738551.0 95300.0 0.7 762366.0 135000.0 1.03 1.2203 0.982 3000225 BCB01_000260 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M23 mock treatment 721845.0 78600.0 0.57 695013.0 68100.0 0.52 0.7721 0.9986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 M24 mock treatment 669802.0 26600.0 0.19 678720.0 51800.0 0.39 0.4155 0.9471 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N01 mock treatment 632638.0 -10600.0 -0.08 647156.0 20200.0 0.15 0.0537 0.3124 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N02 mock treatment 637063.0 -6180.0 -0.05 637245.0 10300.0 0.08 0.0234 0.2588 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N03 compound treatment 655979.0 12700.0 0.09 681926.0 55000.0 0.42 0.3612 0.8441 3093652 BCB01_000261 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(C#N)cc5)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N04 compound treatment 554020.0 -89200.0 -0.65 653190.0 26200.0 0.2 -0.3204 -0.4696 3093653 BCB01_000262 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N05 compound treatment 769142.0 126000.0 0.92 788783.0 162000.0 1.23 1.5204 0.9899 3000227 BCB01_000263 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N06 compound treatment 637287.0 -5950.0 -0.04 603908.0 -23000.0 -0.18 -0.1545 -0.8569 3093654 BCB01_000264 C/C=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N07 compound treatment 514292.0 -129000.0 -0.94 703168.0 76200.0 0.58 -0.2574 -0.2326 3093655 BCB01_000265 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N08 compound treatment 714216.0 71000.0 0.52 559803.0 -67100.0 -0.51 0.0063 0.0087 3000229 BCB01_000266 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N09 compound treatment 641151.0 -2090.0 -0.02 603703.0 -23200.0 -0.18 -0.1357 -0.7654 3093656 BCB01_000267 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N10 compound treatment 690147.0 46900.0 0.34 596219.0 -30700.0 -0.23 0.0775 0.1868 3000231 BCB01_000268 CC(C)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N11 compound treatment 536092.0 -107000.0 -0.78 708883.0 81900.0 0.62 -0.1139 -0.1139 3093657 BCB01_000269 CC(C)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N12 compound treatment 692090.0 48800.0 0.36 777289.0 150000.0 1.14 1.0602 0.886 3000297 BCB01_000270 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N13 compound treatment 729871.0 86600.0 0.63 478307.0 -149000.0 -1.13 -0.3505 -0.2707 3000298 BCB01_000271 OB(O)c1ccc(cc1)C(O)C2C=CC3CN(C(=O)C3N2Nc4ccc(C#N)cc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N14 compound treatment 641089.0 -2150.0 -0.02 582073.0 -44900.0 -0.34 -0.2522 -0.739 3000299 BCB01_000272 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O)c5ccccc15 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N15 compound treatment 766082.0 123000.0 0.9 680095.0 53100.0 0.4 0.9207 0.9348 3093658 BCB01_000273 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N16 compound treatment 738087.0 94800.0 0.69 744859.0 118000.0 0.9 1.1239 0.992 3093659 BCB01_000274 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N17 compound treatment 658137.0 14900.0 0.11 709354.0 82400.0 0.63 0.5197 0.8179 3000301 BCB01_000275 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N18 compound treatment 695012.0 51800.0 0.38 749363.0 122000.0 0.93 0.9253 0.9215 3093660 BCB01_000276 CC(C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N19 compound treatment 845666.0 202000.0 1.48 812275.0 185000.0 1.41 2.0423 0.9997 3093661 BCB01_000277 COC(=O)c1ccc(o1)C(O)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N20 compound treatment 745806.0 103000.0 0.75 782934.0 156000.0 1.19 1.3683 0.9757 3000302 BCB01_000278 CC(CC(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C)o4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N21 compound treatment 886501.0 243000.0 1.78 828701.0 202000.0 1.53 2.3417 0.9972 3093662 BCB01_000279 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N22 compound treatment 683757.0 40500.0 0.3 720883.0 93900.0 0.71 0.7141 0.9242 3093663 BCB01_000280 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N23 mock treatment 778401.0 135000.0 0.99 700408.0 73500.0 0.56 1.0936 0.9634 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 N24 mock treatment 875456.0 232000.0 1.7 757207.0 130000.0 0.99 1.9005 0.967 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O01 mock treatment 643503.0 263.0 0.0 685002.0 58100.0 0.44 0.3132 0.7102 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O02 mock treatment 618046.0 -25200.0 -0.18 625465.0 -1480.0 -0.01 -0.1382 -0.7489 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O03 compound treatment 696625.0 53400.0 0.39 633161.0 6210.0 0.05 0.3094 0.7869 3000303 BCB01_000281 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O04 compound treatment 698521.0 55300.0 0.4 755072.0 128000.0 0.97 0.9741 0.9242 3093664 BCB01_000282 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O05 compound treatment 620733.0 -22500.0 -0.16 672461.0 45500.0 0.35 0.1281 0.3345 3093665 BCB01_000283 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5ccc(s5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O06 compound treatment 672324.0 29100.0 0.21 791873.0 165000.0 1.25 1.0363 0.8155 3000304 BCB01_000284 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O07 compound treatment 624677.0 -18600.0 -0.14 703550.0 76600.0 0.58 0.3155 0.528 3093666 BCB01_000285 Cn1cccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O08 compound treatment 597871.0 -45400.0 -0.33 693489.0 66500.0 0.51 0.1228 0.2031 3093667 BCB01_000286 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)C(=O)C)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O09 compound treatment 769979.0 127000.0 0.93 759534.0 133000.0 1.01 1.3676 0.9991 3000307 BCB01_000287 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O10 compound treatment 654900.0 11700.0 0.09 877346.0 250000.0 1.9 1.4054 0.7381 3093736 BCB01_000288 CC(C)c1ccc(NN2C3C(C=CC2C(O)C4CCCCC4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O11 compound treatment 804145.0 161000.0 1.18 807448.0 181000.0 1.37 1.8017 0.9971 3000308 BCB01_000289 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O12 compound treatment 750292.0 107000.0 0.78 680642.0 53700.0 0.41 0.842 0.9538 3093737 BCB01_000290 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O13 compound treatment 807700.0 164000.0 1.2 707044.0 80100.0 0.61 1.2807 0.9502 3093738 BCB01_000291 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O14 compound treatment 754946.0 112000.0 0.82 816592.0 190000.0 1.44 1.5964 0.9639 3000310 BCB01_000292 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)C(C)C)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O15 compound treatment 672933.0 29700.0 0.22 936778.0 310000.0 2.35 1.8179 0.7691 3093739 BCB01_000293 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O16 compound treatment 632042.0 -11200.0 -0.08 776795.0 150000.0 1.14 0.747 0.6545 3000311 BCB01_000294 CC(C)c1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C3=O)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O17 compound treatment 623816.0 -19400.0 -0.14 686622.0 59700.0 0.45 0.2201 0.4633 3093740 BCB01_000295 OC(C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O18 compound treatment 537131.0 -106000.0 -0.78 785099.0 158000.0 1.2 0.3008 0.2103 3093741 BCB01_000296 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O19 compound treatment 780518.0 137000.0 1.0 690505.0 63600.0 0.48 1.0513 0.9437 3000313 BCB01_000297 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O20 compound treatment 757953.0 115000.0 0.84 794140.0 167000.0 1.27 1.4913 0.9797 3093742 BCB01_000298 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2Nc4ccc(cc4)C(C)C)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O21 compound treatment 781467.0 138000.0 1.01 813266.0 186000.0 1.42 1.7157 0.9864 3000315 BCB01_000299 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O22 compound treatment 722062.0 78800.0 0.58 721323.0 94400.0 0.72 0.9146 0.9941 3093743 BCB01_000300 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)C(C)C)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O23 mock treatment 687181.0 43900.0 0.32 725300.0 98400.0 0.75 0.7556 0.9289 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 O24 mock treatment 823820.0 181000.0 1.32 651553.0 24600.0 0.19 1.066 0.7992 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P01 mock treatment 672537.0 29300.0 0.21 708099.0 81200.0 0.62 0.5874 0.9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P02 mock treatment 744087.0 101000.0 0.74 726061.0 99100.0 0.75 1.0539 0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P03 compound treatment 778477.0 135000.0 0.99 773461.0 147000.0 1.11 1.4864 0.9983 3000135 BCB01_000301 CC(C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P04 compound treatment 685083.0 41800.0 0.31 803107.0 176000.0 1.34 1.1627 0.8469 3000137 BCB01_000302 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P05 compound treatment 680743.0 37500.0 0.27 676244.0 49300.0 0.37 0.4587 0.9883 3000138 BCB01_000303 CC(CC(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P06 compound treatment 697882.0 54600.0 0.4 841418.0 214000.0 1.63 1.4346 0.8552 3000139 BCB01_000304 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(C#N)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P07 compound treatment 716807.0 73600.0 0.54 743593.0 117000.0 0.89 1.007 0.9714 3093744 BCB01_000305 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P08 compound treatment 687884.0 44600.0 0.33 703239.0 76300.0 0.58 0.6407 0.9631 3000141 BCB01_000306 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P09 compound treatment 712376.0 69100.0 0.51 766982.0 140000.0 1.06 1.1097 0.9422 3093745 BCB01_000307 OC(C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P10 compound treatment 670905.0 27700.0 0.2 769598.0 143000.0 1.08 0.9093 0.8249 3093746 BCB01_000308 OC(C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P11 compound treatment 683929.0 40700.0 0.3 807921.0 181000.0 1.37 1.1826 0.8407 3000143 BCB01_000309 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccc(C#N)cc4)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P12 compound treatment 656307.0 13100.0 0.1 842706.0 216000.0 1.64 1.2266 0.7471 3093747 BCB01_000310 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccn4)C(=O)NC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P13 compound treatment 729917.0 86700.0 0.63 817584.0 191000.0 1.45 1.4723 0.9313 3093748 BCB01_000311 CC(=CCC/C=C(\C)/C(O)C1C=CC2C(N1Nc3ccc(C#N)cc3)C(=O)N(C2=O)c4ccccc4)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P14 compound treatment 729366.0 86100.0 0.63 784689.0 158000.0 1.2 1.2927 0.9549 3000145 BCB01_000312 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P15 compound treatment 467824.0 -175000.0 -1.28 520455.0 -106000.0 -0.81 -1.4791 -0.9753 3093749 BCB01_000313 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P16 compound treatment 812802.0 170000.0 1.24 871896.0 245000.0 1.86 2.1926 0.9805 3093750 BCB01_000314 OCC(O)C(O)C1C=CC2C(N1Nc3ccccn3)C(=O)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P17 compound treatment 526656.0 -117000.0 -0.85 671595.0 44600.0 0.34 -0.363 -0.3956 3000147 BCB01_000315 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(I)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P18 compound treatment 651603.0 8360.0 0.06 761236.0 134000.0 1.02 0.7646 0.7482 3093751 BCB01_000316 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P19 compound treatment 686321.0 43100.0 0.32 762148.0 135000.0 1.03 0.949 0.8834 3093752 BCB01_000317 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P20 compound treatment 819916.0 177000.0 1.29 853361.0 226000.0 1.72 2.1299 0.9901 3000149 BCB01_000318 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P21 compound treatment 763962.0 121000.0 0.88 843100.0 216000.0 1.64 1.7854 0.9576 3093752 BCB01_000319 OC(C1C=CC2C(N1Nc3ccc(Cl)cc3Cl)C(=O)NC2=O)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P22 compound treatment 799465.0 156000.0 1.14 787990.0 161000.0 1.22 1.6729 0.9994 3093753 BCB01_000320 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P23 mock treatment 773712.0 130000.0 0.95 727753.0 101000.0 0.77 1.2162 0.9941 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2000 P24 mock treatment 749190.0 106000.0 0.77 857916.0 231000.0 1.75 1.7886 0.9325 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A01 compound treatment 476830.0 -160000.0 -1.17 589861.0 -84200.0 -0.64 -1.2787 -0.9598 3000745 BCB02_000001 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A02 compound treatment 500783.0 -136000.0 -0.99 696458.0 22400.0 0.17 -0.5822 -0.5776 3000746 BCB02_000002 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A03 compound treatment 549225.0 -87400.0 -0.64 644503.0 -29600.0 -0.22 -0.6108 -0.9015 3000747 BCB02_000003 OC(C1CCCCC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A04 compound treatment 545598.0 -91000.0 -0.67 662830.0 -11200.0 -0.09 -0.5311 -0.7913 3000748 BCB02_000004 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A05 compound treatment 487928.0 -149000.0 -1.09 621987.0 -52100.0 -0.4 -1.0488 -0.9062 3000749 BCB02_000005 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A06 compound treatment 526669.0 -110000.0 -0.8 567630.0 -106000.0 -0.81 -1.1404 -1.0 3000750 BCB02_000006 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A07 compound treatment 534927.0 -102000.0 -0.74 736832.0 62800.0 0.48 -0.1888 -0.2137 3093754 BCB02_000007 CCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A08 compound treatment 549763.0 -86900.0 -0.64 581998.0 -92100.0 -0.7 -0.9438 -0.9989 2065163 BCB02_000008 CCOC(=O)/C=C/c1ccccc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A09 compound treatment 601588.0 -35100.0 -0.26 647475.0 -26600.0 -0.2 -0.3241 -0.993 3093755 BCB02_000009 CCCCCCCCCCC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A10 compound treatment 477058.0 -160000.0 -1.17 694859.0 20800.0 0.16 -0.7135 -0.6059 3000752 BCB02_000010 CCOC(=O)/C=C/c1cc(F)ccc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A11 compound treatment 515338.0 -121000.0 -0.89 604611.0 -69500.0 -0.53 -1.0003 -0.9692 3093756 BCB02_000011 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A12 compound treatment 436023.0 -201000.0 -1.47 631048.0 -43000.0 -0.33 -1.2685 -0.8439 3000753 BCB02_000012 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A13 compound treatment 593758.0 -42900.0 -0.31 726350.0 52300.0 0.4 0.0591 0.1168 3093757 BCB02_000013 COc1ccc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A14 compound treatment 552678.0 -84000.0 -0.61 599630.0 -74400.0 -0.57 -0.834 -0.9992 3000754 BCB02_000014 CCOC(=O)/C=C/c1cccc(OC)c1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A15 compound treatment 593418.0 -43200.0 -0.32 685698.0 11600.0 0.09 -0.161 -0.4905 3093824 BCB02_000015 COc1cc(OC)c(cc1Br)C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A16 compound treatment 528257.0 -108000.0 -0.79 623288.0 -50800.0 -0.39 -0.8332 -0.9452 3000755 BCB02_000016 CCOC(=O)/C=C/c1cccc(C)c1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A17 mock treatment 495461.0 -141000.0 -1.03 671029.0 -3030.0 -0.02 -0.7464 -0.7227 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A18 mock treatment 565457.0 -71200.0 -0.52 634735.0 -39300.0 -0.3 -0.5794 -0.9653 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A19 mock treatment 551489.0 -85200.0 -0.62 653078.0 -21000.0 -0.16 -0.5531 -0.8604 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A20 mock treatment 566394.0 -70200.0 -0.51 612954.0 -61100.0 -0.46 -0.6915 -0.9987 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A21 mock treatment 576643.0 -60000.0 -0.44 600612.0 -73400.0 -0.56 -0.7048 -0.9929 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A22 mock treatment 644741.0 8100.0 0.06 666251.0 -7810.0 -0.06 -1.0E-4 -9.0E-4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A23 mock treatment 626865.0 -9780.0 -0.07 549431.0 -125000.0 -0.95 -0.72 -0.7583 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 A24 mock treatment 530582.0 -106000.0 -0.78 600863.0 -73200.0 -0.56 -0.9417 -0.9867 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B01 compound treatment 543264.0 -93400.0 -0.68 699675.0 25600.0 0.19 -0.3453 -0.4863 3093825 BCB02_000017 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B02 compound treatment 585977.0 -50700.0 -0.37 742381.0 68300.0 0.52 0.105 0.1647 3000756 BCB02_000018 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B03 compound treatment 635643.0 -999.0 -0.01 643955.0 -30100.0 -0.23 -0.1669 -0.7293 3093826 BCB02_000019 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B04 compound treatment 522964.0 -114000.0 -0.83 648203.0 -25900.0 -0.2 -0.7267 -0.8508 3000757 BCB02_000020 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B05 compound treatment 602444.0 -34200.0 -0.25 588151.0 -85900.0 -0.65 -0.6383 -0.9133 3093827 BCB02_000021 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(s5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B06 compound treatment 594842.0 -41800.0 -0.31 655510.0 -18600.0 -0.14 -0.3158 -0.9382 3093828 BCB02_000022 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B07 compound treatment 583890.0 -52800.0 -0.39 623076.0 -51000.0 -0.39 -0.5467 -1.0 3000758 BCB02_000023 CC(C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B08 compound treatment 598997.0 -37600.0 -0.28 516707.0 -157000.0 -1.2 -1.0399 -0.8478 3093829 BCB02_000024 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B09 compound treatment 586043.0 -50600.0 -0.37 591542.0 -82500.0 -0.63 -0.7049 -0.9684 3000759 BCB02_000025 CC(CC(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(C)o5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B10 compound treatment 605333.0 -31300.0 -0.23 560494.0 -114000.0 -0.86 -0.772 -0.8648 3093830 BCB02_000026 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B11 compound treatment 666007.0 29400.0 0.21 633699.0 -40400.0 -0.31 -0.065 -0.1735 3093831 BCB02_000027 OC(Cc1ccccc1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B12 compound treatment 644233.0 7590.0 0.06 513133.0 -161000.0 -1.22 -0.8252 -0.6743 3000760 BCB02_000028 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B13 compound treatment 652553.0 15900.0 0.12 641735.0 -32300.0 -0.25 -0.0914 -0.3362 3093832 BCB02_000029 OC(C1CCCCC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B14 compound treatment 631097.0 -5540.0 -0.04 616978.0 -57100.0 -0.43 -0.3353 -0.7699 3093833 BCB02_000030 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B15 compound treatment 704962.0 68300.0 0.5 745307.0 71200.0 0.54 0.736 0.9992 3000761 BCB02_000031 CC(=C)[C@H]1CCC(=CC1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B16 compound treatment 666471.0 29800.0 0.22 610569.0 -63500.0 -0.48 -0.1868 -0.3529 3093834 BCB02_000032 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B17 mock treatment 693710.0 57100.0 0.42 653173.0 -20900.0 -0.16 0.1829 0.4096 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B18 mock treatment 574568.0 -62100.0 -0.45 575566.0 -98500.0 -0.75 -0.8501 -0.9713 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B19 mock treatment 609138.0 -27500.0 -0.2 607057.0 -67000.0 -0.51 -0.5022 -0.9175 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B20 mock treatment 549325.0 -87300.0 -0.64 588214.0 -85800.0 -0.65 -0.9127 -0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B21 mock treatment 655169.0 18500.0 0.14 644789.0 -29300.0 -0.22 -0.0614 -0.2359 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B22 mock treatment 529735.0 -107000.0 -0.78 619949.0 -54100.0 -0.41 -0.8435 -0.9549 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B23 mock treatment 622522.0 -14100.0 -0.1 639980.0 -34100.0 -0.26 -0.2561 -0.9187 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 B24 mock treatment 628985.0 -7660.0 -0.06 603811.0 -70300.0 -0.53 -0.417 -0.777 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C01 compound treatment 586435.0 -50200.0 -0.37 573898.0 -100000.0 -0.76 -0.7977 -0.9441 3093835 BCB02_000033 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C02 compound treatment 569630.0 -67000.0 -0.49 599175.0 -74900.0 -0.57 -0.7488 -0.9972 3000762 BCB02_000034 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C03 compound treatment 569969.0 -66700.0 -0.49 601655.0 -72400.0 -0.55 -0.7337 -0.9982 3000763 BCB02_000035 Cc1ccccc1C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C04 compound treatment 505172.0 -131000.0 -0.96 590682.0 -83400.0 -0.63 -1.1277 -0.9795 3093836 BCB02_000036 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C05 compound treatment 619408.0 -17200.0 -0.13 666554.0 -7510.0 -0.06 -0.1294 -0.9357 3093837 BCB02_000037 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C06 compound treatment 375604.0 -261000.0 -1.91 488682.0 -185000.0 -1.41 -2.3457 -0.9888 3000764 BCB02_000038 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C07 compound treatment 517669.0 -119000.0 -0.87 578335.0 -95700.0 -0.73 -1.1294 -0.996 3093838 BCB02_000039 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C08 compound treatment 371447.0 -265000.0 -1.94 392607.0 -281000.0 -2.14 -2.8833 -0.9988 3000765 BCB02_000040 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C09 compound treatment 488406.0 -148000.0 -1.08 519635.0 -154000.0 -1.17 -1.5961 -0.9992 3093839 BCB02_000041 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C10 compound treatment 530930.0 -106000.0 -0.77 654662.0 -19400.0 -0.15 -0.6509 -0.827 3000766 BCB02_000042 O=c1oc2ccccc2cc1C#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C11 compound treatment 665569.0 28900.0 0.21 693362.0 19300.0 0.15 0.2533 0.984 3093840 BCB02_000043 OC(C1CCC=CC1)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C12 compound treatment 621148.0 -15500.0 -0.11 797563.0 124000.0 0.94 0.5833 0.6172 3000767 BCB02_000044 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C13 compound treatment 619061.0 -17600.0 -0.13 618030.0 -56000.0 -0.43 -0.3919 -0.8814 3093841 BCB02_000045 CC(=O)n1cc(C(O)C2C=CC3C(N2n4cnnc4)C(=O)N(Cc5ccccc5)C3=O)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C14 compound treatment 549875.0 -86800.0 -0.63 707963.0 33900.0 0.26 -0.2666 -0.3893 3000768 BCB02_000046 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C15 compound treatment 523108.0 -114000.0 -0.83 710492.0 36400.0 0.28 -0.3914 -0.4472 3093842 BCB02_000047 CCCCC(CC)C(O)C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C16 compound treatment 609077.0 -27600.0 -0.2 743276.0 69200.0 0.53 0.2293 0.4071 3093843 BCB02_000048 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C17 mock treatment 643925.0 7280.0 0.05 700135.0 26100.0 0.2 0.1777 0.8665 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C18 mock treatment 628166.0 -8480.0 -0.06 705146.0 31100.0 0.24 0.1231 0.5044 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C19 mock treatment 652511.0 15900.0 0.12 646690.0 -27400.0 -0.21 -0.065 -0.2728 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C20 mock treatment 667724.0 31100.0 0.23 637228.0 -36800.0 -0.28 -0.0371 -0.103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C21 mock treatment 625547.0 -11100.0 -0.08 690042.0 16000.0 0.12 0.0285 0.195 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C22 mock treatment 607229.0 -29400.0 -0.22 719801.0 45700.0 0.35 0.0936 0.229 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C23 mock treatment 628104.0 -8540.0 -0.06 627625.0 -46400.0 -0.35 -0.2936 -0.8195 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 C24 mock treatment 581606.0 -55000.0 -0.4 593375.0 -80700.0 -0.61 -0.718 -0.9792 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D01 compound treatment 674360.0 37700.0 0.28 652347.0 -21700.0 -0.16 0.0784 0.2439 3000769 BCB02_000049 CCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D02 compound treatment 532023.0 -105000.0 -0.77 638969.0 -35100.0 -0.27 -0.7295 -0.9004 3093844 BCB02_000050 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D03 compound treatment 591761.0 -44900.0 -0.33 597227.0 -76800.0 -0.58 -0.6448 -0.9629 3093845 BCB02_000051 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5c(F)cccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D04 compound treatment 531493.0 -105000.0 -0.77 641155.0 -32900.0 -0.25 -0.7205 -0.8911 3000770 BCB02_000052 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D05 compound treatment 611789.0 -24900.0 -0.18 692250.0 18200.0 0.14 -0.0308 -0.135 3093846 BCB02_000053 Cc1cc(C)c(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c(C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D06 compound treatment 578746.0 -57900.0 -0.42 578467.0 -95600.0 -0.73 -0.8129 -0.967 3000771 BCB02_000054 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D07 compound treatment 529995.0 -107000.0 -0.78 553482.0 -121000.0 -0.92 -1.1992 -0.9968 3092586 BCB02_000055 Cc1ccccc1C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D08 compound treatment 406092.0 -231000.0 -1.69 399460.0 -275000.0 -2.09 -2.6673 -0.9944 3092495 BCB02_000056 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D09 compound treatment 521770.0 -115000.0 -0.84 496730.0 -177000.0 -1.35 -1.5466 -0.9742 3000772 BCB02_000057 OC(C1CCC=CC1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D10 compound treatment 655265.0 18600.0 0.14 626916.0 -47100.0 -0.36 -0.1569 -0.4096 3092496 BCB02_000058 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D11 compound treatment 589369.0 -47300.0 -0.35 637923.0 -36100.0 -0.27 -0.4386 -0.9935 3092497 BCB02_000059 CC(=O)n1cc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D12 compound treatment 500254.0 -136000.0 -1.0 487257.0 -187000.0 -1.42 -1.7087 -0.9851 3000773 BCB02_000060 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D13 compound treatment 614781.0 -21900.0 -0.16 524104.0 -150000.0 -1.14 -0.9186 -0.7985 3092498 BCB02_000061 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D14 compound treatment 616880.0 -19800.0 -0.14 693246.0 19200.0 0.15 9.0E-4 0.0042 3000774 BCB02_000062 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D15 compound treatment 612162.0 -24500.0 -0.18 679548.0 5490.0 0.04 -0.0971 -0.5284 3092499 BCB02_000063 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D16 compound treatment 518153.0 -118000.0 -0.87 466016.0 -208000.0 -1.58 -1.7303 -0.96 3000775 BCB02_000064 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D17 mock treatment 551186.0 -85500.0 -0.62 623423.0 -50600.0 -0.38 -0.7139 -0.9728 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D18 mock treatment 575672.0 -61000.0 -0.45 606408.0 -67700.0 -0.51 -0.6787 -0.9975 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D19 mock treatment 583375.0 -53300.0 -0.39 569133.0 -105000.0 -0.8 -0.8391 -0.9458 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D20 mock treatment 650545.0 13900.0 0.1 622107.0 -52000.0 -0.39 -0.2072 -0.5083 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D21 mock treatment 555884.0 -80800.0 -0.59 696268.0 22200.0 0.17 -0.2983 -0.4857 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D22 mock treatment 636504.0 -138.0 0.0 703018.0 29000.0 0.22 0.1548 0.7039 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D23 mock treatment 680965.0 44300.0 0.32 655715.0 -18300.0 -0.14 0.1306 0.3703 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 D24 mock treatment 747064.0 110000.0 0.81 622144.0 -51900.0 -0.39 0.2921 0.325 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E01 compound treatment 574197.0 -62400.0 -0.46 631211.0 -42900.0 -0.33 -0.5531 -0.9862 3092500 BCB02_000065 CCCCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E02 compound treatment 538717.0 -97900.0 -0.72 652504.0 -21600.0 -0.16 -0.6222 -0.8469 3000776 BCB02_000066 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E03 compound treatment 634620.0 -2020.0 -0.01 687311.0 13200.0 0.1 0.0607 0.5968 3000847 BCB02_000067 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3n5cnnc5)C(=O)N(Cc6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E04 compound treatment 495448.0 -141000.0 -1.03 629321.0 -44700.0 -0.34 -0.9705 -0.8927 3000848 BCB02_000068 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E05 compound treatment 313202.0 -323000.0 -2.37 318267.0 -356000.0 -2.7 -3.5838 -0.9978 3000849 BCB02_000069 OC(C1C=CC2C(N1n3cnnc3)C(=O)N(Cc4ccccc4)C2=O)c5ccc(Br)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E06 compound treatment 518423.0 -118000.0 -0.86 671428.0 -2630.0 -0.02 -0.6255 -0.7233 3000850 BCB02_000070 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E07 compound treatment 593282.0 -43400.0 -0.32 702230.0 28200.0 0.21 -0.0729 -0.1906 3000851 BCB02_000071 OC(/C=C/c1ccc(cc1)[N+](=O)[O-])C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E08 compound treatment 492463.0 -144000.0 -1.05 567347.0 -107000.0 -0.81 -1.3188 -0.9916 3092501 BCB02_000072 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E09 compound treatment 598722.0 -37900.0 -0.28 711849.0 37800.0 0.29 0.0069 0.0173 3000852 BCB02_000073 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E10 compound treatment 605068.0 -31600.0 -0.23 586394.0 -87700.0 -0.67 -0.6342 -0.8997 3092502 BCB02_000074 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E11 compound treatment 614828.0 -21800.0 -0.16 726362.0 52300.0 0.4 0.1681 0.3927 3092503 BCB02_000075 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E12 compound treatment 607263.0 -29400.0 -0.21 671686.0 -2380.0 -0.02 -0.1647 -0.7638 3000853 BCB02_000076 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E13 compound treatment 688609.0 52000.0 0.38 732570.0 58500.0 0.44 0.583 0.997 3092504 BCB02_000077 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E14 compound treatment 551024.0 -85600.0 -0.63 669487.0 -4570.0 -0.03 -0.4673 -0.7452 3000854 BCB02_000078 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E15 compound treatment 605210.0 -31400.0 -0.23 770411.0 96300.0 0.73 0.355 0.4628 3092505 BCB02_000079 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E16 compound treatment 651484.0 14800.0 0.11 630544.0 -43500.0 -0.33 -0.157 -0.4512 3000855 BCB02_000080 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E17 mock treatment 562310.0 -74300.0 -0.54 603694.0 -70400.0 -0.53 -0.7624 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E18 mock treatment 564612.0 -72000.0 -0.53 710196.0 36100.0 0.27 -0.1784 -0.3003 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E19 mock treatment 644033.0 7390.0 0.05 720293.0 46200.0 0.35 0.2866 0.8064 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E20 mock treatment 669196.0 32600.0 0.24 618949.0 -55100.0 -0.42 -0.1277 -0.2652 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E21 mock treatment 673111.0 36500.0 0.27 713366.0 39300.0 0.3 0.3997 0.9984 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E22 mock treatment 657585.0 20900.0 0.15 679871.0 5810.0 0.04 0.1395 0.8752 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E23 mock treatment 648851.0 12200.0 0.09 652810.0 -21300.0 -0.16 -0.051 -0.2766 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 E24 mock treatment 551578.0 -85100.0 -0.62 561385.0 -113000.0 -0.86 -1.0451 -0.9877 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F01 compound treatment 573140.0 -63500.0 -0.46 620355.0 -53700.0 -0.41 -0.6169 -0.9979 3092506 BCB02_000081 OC(COCc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F02 compound treatment 623128.0 -13500.0 -0.1 542316.0 -132000.0 -1.0 -0.7776 -0.7732 3092507 BCB02_000082 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F03 compound treatment 612598.0 -24000.0 -0.18 707343.0 33300.0 0.25 0.0544 0.1768 3000856 BCB02_000083 COc1ccc(NN2C3C(C=CC2C(O)c4ccccc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F04 compound treatment 459189.0 -177000.0 -1.3 636277.0 -37800.0 -0.29 -1.1206 -0.8431 3092508 BCB02_000084 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F05 compound treatment 523202.0 -113000.0 -0.83 676790.0 2730.0 0.02 -0.572 -0.6892 3092509 BCB02_000085 CCCCC(O)C1C=CC2C(N1Nc3ccc(OC)cc3)C(=O)N(C4CCCCC4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F06 compound treatment 437501.0 -199000.0 -1.46 547876.0 -126000.0 -0.96 -1.7076 -0.9794 3000857 BCB02_000086 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F07 compound treatment 549074.0 -87600.0 -0.64 745036.0 71000.0 0.54 -0.0716 -0.0855 3092510 BCB02_000087 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(F)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F08 compound treatment 482131.0 -155000.0 -1.13 569138.0 -105000.0 -0.8 -1.3626 -0.9854 3000858 BCB02_000088 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F09 compound treatment 534114.0 -103000.0 -0.75 738824.0 64800.0 0.49 -0.1823 -0.2033 3092511 BCB02_000089 C/C=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F10 compound treatment 347350.0 -289000.0 -2.12 461635.0 -212000.0 -1.61 -2.6371 -0.9911 3000859 BCB02_000090 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F11 compound treatment 542447.0 -94200.0 -0.69 548781.0 -125000.0 -0.95 -1.1601 -0.9874 3092512 BCB02_000091 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F12 compound treatment 536650.0 -100000.0 -0.73 432953.0 -241000.0 -1.83 -1.8122 -0.9189 3092513 BCB02_000092 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F13 compound treatment 515838.0 -121000.0 -0.88 641516.0 -32500.0 -0.25 -0.7995 -0.8715 3000860 BCB02_000093 CN(C)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F14 compound treatment 458802.0 -178000.0 -1.3 544018.0 -130000.0 -0.99 -1.6182 -0.9908 3092514 BCB02_000094 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F15 compound treatment 598867.0 -37800.0 -0.28 680353.0 6290.0 0.05 -0.1615 -0.5762 3092515 BCB02_000095 COc1cc(cc(OC)c1OC)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F16 compound treatment 450504.0 -186000.0 -1.36 567947.0 -106000.0 -0.81 -1.5326 -0.9687 3000861 BCB02_000096 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F17 mock treatment 545937.0 -90700.0 -0.66 636051.0 -38000.0 -0.29 -0.6732 -0.9306 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F18 mock treatment 552857.0 -83800.0 -0.61 561790.0 -112000.0 -0.85 -1.0364 -0.9868 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F19 mock treatment 676874.0 40200.0 0.29 634568.0 -39500.0 -0.3 -0.0041 -0.0098 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F20 mock treatment 672669.0 36000.0 0.26 580516.0 -93500.0 -0.71 -0.3162 -0.4172 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F21 mock treatment 582004.0 -54600.0 -0.4 672450.0 -1610.0 -0.01 -0.2912 -0.7284 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F22 mock treatment 618480.0 -18200.0 -0.13 667575.0 -6490.0 -0.05 -0.1288 -0.9089 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F23 mock treatment 699006.0 62400.0 0.46 655828.0 -18200.0 -0.14 0.2245 0.4711 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 F24 mock treatment 625210.0 -11400.0 -0.08 614435.0 -59600.0 -0.45 -0.3794 -0.8237 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G01 compound treatment 564188.0 -72500.0 -0.53 600481.0 -73600.0 -0.56 -0.7699 -0.9996 3092516 BCB02_000097 CC(C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G02 compound treatment 633519.0 -3120.0 -0.02 665382.0 -8680.0 -0.07 -0.0628 -0.8996 3000862 BCB02_000098 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G03 compound treatment 450605.0 -186000.0 -1.36 514940.0 -159000.0 -1.21 -1.8168 -0.9983 3092587 BCB02_000099 CCCCCCCCCCC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G04 compound treatment 597994.0 -38600.0 -0.28 719171.0 45100.0 0.34 0.0425 0.0956 3000863 BCB02_000100 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G05 compound treatment 709961.0 73300.0 0.54 729836.0 55800.0 0.42 0.6788 0.9932 3092588 BCB02_000101 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G06 compound treatment 561015.0 -75600.0 -0.55 635319.0 -38700.0 -0.29 -0.5992 -0.9564 3092589 BCB02_000102 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G07 compound treatment 558636.0 -78000.0 -0.57 676533.0 2470.0 0.02 -0.3901 -0.6835 3000864 BCB02_000103 COc1ccc(C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5)c6ccccc16 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G08 compound treatment 597902.0 -38700.0 -0.28 623086.0 -51000.0 -0.39 -0.4742 -0.9882 3092590 BCB02_000104 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G09 compound treatment 531161.0 -105000.0 -0.77 572245.0 -102000.0 -0.77 -1.0924 -1.0 3092591 BCB02_000105 COc1ccc(cc1OCc2ccccc2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G10 compound treatment 531775.0 -105000.0 -0.77 687556.0 13500.0 0.1 -0.4698 -0.6072 3000865 BCB02_000106 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G11 compound treatment 578179.0 -58500.0 -0.43 765700.0 91600.0 0.7 0.1899 0.2325 3092592 BCB02_000107 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccn5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G12 compound treatment 581660.0 -55000.0 -0.4 693810.0 19700.0 0.15 -0.1782 -0.4153 3000866 BCB02_000108 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G13 compound treatment 590292.0 -46300.0 -0.34 620601.0 -53500.0 -0.41 -0.5269 -0.996 3092593 BCB02_000109 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G14 compound treatment 563570.0 -73100.0 -0.53 699039.0 25000.0 0.19 -0.2437 -0.4297 3000867 BCB02_000110 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G15 compound treatment 312873.0 -324000.0 -2.37 332429.0 -342000.0 -2.6 -3.5094 -0.999 3092594 BCB02_000111 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G16 compound treatment 659623.0 23000.0 0.17 718081.0 44000.0 0.33 0.3553 0.9493 3092595 BCB02_000112 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G17 mock treatment 610790.0 -25900.0 -0.19 720649.0 46600.0 0.35 0.1166 0.2905 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G18 mock treatment 546322.0 -90300.0 -0.66 600606.0 -73500.0 -0.56 -0.8616 -0.9965 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G19 mock treatment 620947.0 -15700.0 -0.11 667096.0 -6970.0 -0.05 -0.1186 -0.9382 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G20 mock treatment 661636.0 25000.0 0.18 685984.0 11900.0 0.09 0.1933 0.9475 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G21 mock treatment 610971.0 -25700.0 -0.19 692995.0 18900.0 0.14 -0.031 -0.1313 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G22 mock treatment 619518.0 -17100.0 -0.13 690813.0 16800.0 0.13 0.0014 0.008 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G23 mock treatment 600941.0 -35700.0 -0.26 649745.0 -24300.0 -0.18 -0.3152 -0.9856 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 G24 mock treatment 625349.0 -11300.0 -0.08 584042.0 -90000.0 -0.68 -0.542 -0.7868 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H01 compound treatment 703058.0 66400.0 0.49 692611.0 18500.0 0.14 0.4431 0.8761 3000868 BCB02_000113 CC(=CCC/C(=C/C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H02 compound treatment 577383.0 -59300.0 -0.43 639364.0 -34700.0 -0.26 -0.4928 -0.9716 3092596 BCB02_000114 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H03 compound treatment 564459.0 -72200.0 -0.53 685791.0 11700.0 0.09 -0.3103 -0.5796 3092597 BCB02_000115 OC(CCc1ccccc1)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H04 compound treatment 516714.0 -120000.0 -0.88 608585.0 -65500.0 -0.5 -0.9719 -0.9639 3000869 BCB02_000116 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H05 compound treatment 517906.0 -119000.0 -0.87 677453.0 3390.0 0.03 -0.5958 -0.6858 3092598 BCB02_000117 COc1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccccc4F)C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H06 compound treatment 523056.0 -114000.0 -0.83 719691.0 45600.0 0.35 -0.3423 -0.3803 3000870 BCB02_000118 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H07 compound treatment 590590.0 -46100.0 -0.34 581029.0 -93000.0 -0.71 -0.7379 -0.9425 3000871 BCB02_000119 O=c1cccc(o1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H08 compound treatment 518601.0 -118000.0 -0.86 688140.0 14100.0 0.11 -0.5348 -0.6148 3092599 BCB02_000120 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H09 compound treatment 555676.0 -81000.0 -0.59 596836.0 -77200.0 -0.59 -0.8335 -1.0 3000872 BCB02_000121 COc1cccc(c1)c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H10 compound treatment 414588.0 -222000.0 -1.62 447318.0 -227000.0 -1.72 -2.3663 -0.9996 3092600 BCB02_000122 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H11 compound treatment 563737.0 -72900.0 -0.53 722389.0 48300.0 0.37 -0.1174 -0.1814 1984103 BCB02_000123 Cc1ccc(cc1)c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H12 compound treatment 388748.0 -248000.0 -1.81 489534.0 -185000.0 -1.4 -2.2731 -0.9919 3092601 BCB02_000124 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H13 compound treatment 555223.0 -81400.0 -0.6 748217.0 74200.0 0.56 -0.0227 -0.0277 3000873 BCB02_000125 Clc1cccc(c1)c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H14 compound treatment 570836.0 -65800.0 -0.48 630048.0 -44000.0 -0.33 -0.5767 -0.9842 3000874 BCB02_000126 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H15 compound treatment 614774.0 -21900.0 -0.16 809321.0 135000.0 1.03 0.6135 0.59 3000875 BCB02_000127 Clc1ccccc1c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H16 compound treatment 642671.0 6030.0 0.04 636106.0 -38000.0 -0.29 -0.1727 -0.5921 3092602 BCB02_000128 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H17 mock treatment 697237.0 60600.0 0.44 782391.0 108000.0 0.82 0.8953 0.9578 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H18 mock treatment 698881.0 62200.0 0.46 678589.0 4530.0 0.03 0.3462 0.7584 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H19 mock treatment 673457.0 36800.0 0.27 591431.0 -82600.0 -0.63 -0.2535 -0.3711 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H20 mock treatment 544286.0 -92400.0 -0.68 627457.0 -46600.0 -0.35 -0.7279 -0.9546 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H21 mock treatment 666619.0 30000.0 0.22 711040.0 37000.0 0.28 0.3537 0.9925 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H22 mock treatment 638205.0 1560.0 0.01 569504.0 -105000.0 -0.79 -0.5536 -0.6969 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H23 mock treatment 651616.0 15000.0 0.11 690117.0 16100.0 0.12 0.1637 0.9986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 H24 mock treatment 650932.0 14300.0 0.1 637097.0 -37000.0 -0.28 -0.1247 -0.4161 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I01 compound treatment 583054.0 -53600.0 -0.39 557841.0 -116000.0 -0.88 -0.9014 -0.9332 3092603 BCB02_000129 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I02 compound treatment 485540.0 -151000.0 -1.11 696536.0 22500.0 0.17 -0.6606 -0.5908 3000947 BCB02_000130 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I03 compound treatment 622591.0 -14100.0 -0.1 796465.0 122000.0 0.93 0.5849 0.6252 3000948 BCB02_000131 OC(C(c1ccccc1)c2ccccc2)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I04 compound treatment 628303.0 -8340.0 -0.06 644300.0 -29800.0 -0.23 -0.203 -0.8668 3000949 BCB02_000132 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I05 compound treatment 555863.0 -80800.0 -0.59 708903.0 34800.0 0.26 -0.2306 -0.3562 3000950 BCB02_000133 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I06 compound treatment 531498.0 -105000.0 -0.77 636931.0 -37100.0 -0.28 -0.7432 -0.9074 3000951 BCB02_000134 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I07 compound treatment 571949.0 -64700.0 -0.47 772877.0 98800.0 0.75 0.1963 0.2212 3092604 BCB02_000135 C/C=C/C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I08 compound treatment 562581.0 -74100.0 -0.54 725636.0 51600.0 0.39 -0.1059 -0.1585 3000952 BCB02_000136 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I09 compound treatment 561028.0 -75600.0 -0.55 714802.0 40700.0 0.31 -0.1722 -0.2717 3092605 BCB02_000137 CCC(CC)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I10 compound treatment 569438.0 -67200.0 -0.49 656177.0 -17900.0 -0.14 -0.4436 -0.87 3092606 BCB02_000138 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I11 compound treatment 577812.0 -58800.0 -0.43 823151.0 149000.0 1.13 0.4967 0.4099 3000953 BCB02_000139 CC(C)C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I12 compound treatment 566711.0 -69900.0 -0.51 720784.0 46700.0 0.35 -0.1106 -0.1777 3092607 BCB02_000140 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I13 compound treatment 567511.0 -69100.0 -0.51 729701.0 55600.0 0.42 -0.0586 -0.0889 3092678 BCB02_000141 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccc(O)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I14 compound treatment 643046.0 6400.0 0.05 788824.0 115000.0 0.87 0.6496 0.744 3000954 BCB02_000142 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I15 compound treatment 139214.0 -497000.0 -3.64 147752.0 -526000.0 -4.0 -5.3995 -0.9989 3092679 BCB02_000143 OB(O)c1ccc(cc1)C(O)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I16 compound treatment 459453.0 -177000.0 -1.3 619488.0 -54600.0 -0.41 -1.2094 -0.889 3000955 BCB02_000144 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I17 mock treatment 629533.0 -7110.0 -0.05 692128.0 18100.0 0.14 0.0603 0.4108 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I18 mock treatment 548109.0 -88500.0 -0.65 725508.0 51400.0 0.39 -0.1815 -0.2399 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I19 mock treatment 627064.0 -9580.0 -0.07 733631.0 59600.0 0.45 0.2705 0.5906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I20 mock treatment 619842.0 -16800.0 -0.12 764631.0 90600.0 0.69 0.3996 0.5718 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I21 mock treatment 678767.0 42100.0 0.31 707711.0 33600.0 0.26 0.3986 0.9957 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I22 mock treatment 605974.0 -30700.0 -0.22 676539.0 2480.0 0.02 -0.1453 -0.6455 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I23 mock treatment 696279.0 59600.0 0.44 672163.0 -1900.0 -0.01 0.2982 0.6833 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 I24 mock treatment 672529.0 35900.0 0.26 646557.0 -27500.0 -0.21 0.0378 0.1128 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J01 compound treatment 629201.0 -7440.0 -0.05 656426.0 -17600.0 -0.13 -0.1332 -0.9212 3000956 BCB02_000145 CCCc1cccc(=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J02 compound treatment 510463.0 -126000.0 -0.92 610021.0 -64000.0 -0.49 -0.9965 -0.9553 3092680 BCB02_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J03 compound treatment 545244.0 -91400.0 -0.67 649180.0 -24900.0 -0.19 -0.6063 -0.8728 3000957 BCB02_000147 Fc1ccc(cc1)c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J04 compound treatment 534586.0 -102000.0 -0.75 675141.0 1080.0 0.01 -0.5219 -0.6993 3092681 BCB02_000148 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J05 compound treatment 564333.0 -72300.0 -0.53 812644.0 139000.0 1.05 0.3705 0.3145 3000958 BCB02_000149 O=c1cccc(o1)c2ccc(C#N)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J06 compound treatment 567132.0 -69500.0 -0.51 621936.0 -52100.0 -0.4 -0.6394 -0.9924 3000959 BCB02_000150 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J07 compound treatment 564891.0 -71800.0 -0.52 612713.0 -61300.0 -0.47 -0.7006 -0.9983 3092682 BCB02_000151 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J08 compound treatment 555198.0 -81400.0 -0.6 689599.0 15500.0 0.12 -0.3377 -0.5562 3092683 BCB02_000152 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J09 compound treatment 602572.0 -34100.0 -0.25 745919.0 71900.0 0.55 0.2098 0.3497 3000960 BCB02_000153 FC(F)(F)c1ccccc1c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J10 compound treatment 509307.0 -127000.0 -0.93 569844.0 -104000.0 -0.79 -1.2183 -0.9967 3092684 BCB02_000154 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J11 compound treatment 548765.0 -87900.0 -0.64 638794.0 -35300.0 -0.27 -0.6439 -0.9248 3000961 BCB02_000155 O=c1cccc(o1)c2ccc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J12 compound treatment 551607.0 -85000.0 -0.62 569542.0 -105000.0 -0.79 -1.0012 -0.9927 3000962 BCB02_000156 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J13 compound treatment 685135.0 48500.0 0.35 668143.0 -5920.0 -0.04 0.219 0.6126 3092685 BCB02_000157 O=c1cccc(o1)c2ccco2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J14 compound treatment 539653.0 -97000.0 -0.71 733354.0 59300.0 0.45 -0.183 -0.2178 3092686 BCB02_000158 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J15 compound treatment 738045.0 101000.0 0.74 748825.0 74800.0 0.57 0.926 0.9913 3000963 BCB02_000159 O=c1cccc(CCc2ccccc2)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J16 compound treatment 671121.0 34500.0 0.25 682459.0 8400.0 0.06 0.2234 0.8589 3092687 BCB02_000160 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J17 mock treatment 542180.0 -94500.0 -0.69 772622.0 98600.0 0.75 0.041 0.0402 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J18 mock treatment 683365.0 46700.0 0.34 632108.0 -42000.0 -0.32 0.0162 0.0348 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J19 mock treatment 742518.0 106000.0 0.77 697220.0 23200.0 0.18 0.6719 0.8462 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J20 mock treatment 681986.0 45300.0 0.33 709574.0 35500.0 0.27 0.4252 0.9948 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J21 mock treatment 708574.0 71900.0 0.53 787967.0 114000.0 0.87 0.9838 0.9715 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J22 mock treatment 642032.0 5390.0 0.04 695678.0 21600.0 0.16 0.144 0.8526 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J23 mock treatment 711261.0 74600.0 0.55 585032.0 -89000.0 -0.68 -0.0924 -0.1063 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 J24 mock treatment 676926.0 40300.0 0.29 697713.0 23700.0 0.18 0.3354 0.9719 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K01 compound treatment 624028.0 -12600.0 -0.09 640665.0 -33400.0 -0.25 -0.2446 -0.9062 3000964 BCB02_000161 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K02 compound treatment 502888.0 -134000.0 -0.98 547973.0 -126000.0 -0.96 -1.369 -0.9999 3092688 BCB02_000162 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K03 compound treatment 644320.0 7680.0 0.06 704706.0 30600.0 0.23 0.2043 0.8532 3092689 BCB02_000163 CC(C(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K04 compound treatment 565558.0 -71100.0 -0.52 553583.0 -120000.0 -0.92 -1.0148 -0.9641 3000965 BCB02_000164 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K05 compound treatment 686390.0 49700.0 0.36 676075.0 2010.0 0.02 0.2681 0.7362 3092690 BCB02_000165 CC(CC(O)C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C)o5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K06 compound treatment 613408.0 -23200.0 -0.17 670616.0 -3450.0 -0.03 -0.1387 -0.8065 3000966 BCB02_000166 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K07 compound treatment 742257.0 106000.0 0.77 839200.0 165000.0 1.25 1.4332 0.9729 3092691 BCB02_000167 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K08 compound treatment 573891.0 -62800.0 -0.46 717594.0 43500.0 0.33 -0.0906 -0.1603 3092692 BCB02_000168 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K09 compound treatment 634921.0 -1720.0 -0.01 679082.0 5020.0 0.04 0.0181 0.45 3000967 BCB02_000169 OC(Cc1ccccc1)C2C=CC3C(N2Nc4ccc(cc4)[N+](=O)[O-])C(=O)N(C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K10 compound treatment 620193.0 -16400.0 -0.12 629161.0 -44900.0 -0.34 -0.3263 -0.902 3092693 BCB02_000170 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K11 compound treatment 664751.0 28100.0 0.21 728235.0 54200.0 0.41 0.4364 0.9486 3000968 BCB02_000171 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc(C#N)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K12 compound treatment 553579.0 -83100.0 -0.61 766884.0 92800.0 0.71 0.0691 0.0742 3092694 BCB02_000172 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K13 compound treatment 677464.0 40800.0 0.3 671755.0 -2310.0 -0.02 0.1987 0.6645 3092695 BCB02_000173 OC(C1C=CC2C(N1Nc3ccc(cc3)[N+](=O)[O-])C(=O)N(C2=O)c4ccccc4)c5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K14 compound treatment 590209.0 -46400.0 -0.34 587008.0 -87100.0 -0.66 -0.7077 -0.952 3000969 BCB02_000174 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K15 compound treatment 643078.0 6440.0 0.05 661445.0 -12600.0 -0.1 -0.0345 -0.323 3092696 BCB02_000175 CC1(C)[C@H]2C[C@@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccc(cc5)[N+](=O)[O-])C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K16 compound treatment 584225.0 -52400.0 -0.38 762331.0 88300.0 0.67 0.2031 0.263 3000970 BCB02_000176 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)N(CC)CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K17 mock treatment 600449.0 -36200.0 -0.26 737578.0 63500.0 0.48 0.154 0.2799 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K18 mock treatment 574080.0 -62600.0 -0.46 757908.0 83800.0 0.64 0.1269 0.1618 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K19 mock treatment 583901.0 -52700.0 -0.39 613706.0 -60400.0 -0.46 -0.5969 -0.9963 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K20 mock treatment 589963.0 -46700.0 -0.34 725675.0 51600.0 0.39 0.0359 0.069 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K21 mock treatment 612788.0 -23900.0 -0.17 754141.0 80100.0 0.61 0.3068 0.4848 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K22 mock treatment 559382.0 -77300.0 -0.57 709675.0 35600.0 0.27 -0.2082 -0.3324 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K23 mock treatment 620378.0 -16300.0 -0.12 583743.0 -90300.0 -0.69 -0.5693 -0.8175 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 K24 mock treatment 646196.0 9550.0 0.07 661216.0 -12800.0 -0.1 -0.0196 -0.1633 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L01 compound treatment 633668.0 -2970.0 -0.02 727760.0 53700.0 0.41 0.2731 0.6685 3000971 BCB02_000177 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L02 compound treatment 659949.0 23300.0 0.17 702061.0 28000.0 0.21 0.2709 0.994 3092697 BCB02_000178 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L03 compound treatment 634711.0 -1930.0 -0.01 795982.0 122000.0 0.93 0.6449 0.6962 3000972 BCB02_000179 O=c1cccc(/C=C/c2ccccc2)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L04 compound treatment 631600.0 -5040.0 -0.04 713591.0 39500.0 0.3 0.1863 0.6157 3092698 BCB02_000180 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L05 compound treatment 572451.0 -64200.0 -0.47 753760.0 79700.0 0.61 0.0962 0.1255 3000973 BCB02_000181 O=c1cccc(o1)c2cccc3ccccc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L06 compound treatment 582560.0 -54100.0 -0.4 788956.0 115000.0 0.87 0.3375 0.3522 3092699 BCB02_000182 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L07 compound treatment 589201.0 -47400.0 -0.35 566702.0 -107000.0 -0.82 -0.822 -0.9275 3000974 BCB02_000183 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L08 compound treatment 609606.0 -27000.0 -0.2 590999.0 -83100.0 -0.63 -0.586 -0.8862 3092700 BCB02_000184 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L09 compound treatment 588800.0 -47800.0 -0.35 753131.0 79100.0 0.6 0.1773 0.2551 3092701 BCB02_000185 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L10 compound treatment 626728.0 -9910.0 -0.07 610852.0 -63200.0 -0.48 -0.3908 -0.8047 3000975 BCB02_000186 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L11 compound treatment 538483.0 -98200.0 -0.72 728156.0 54100.0 0.41 -0.217 -0.2624 3092771 BCB02_000187 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L12 compound treatment 578136.0 -58500.0 -0.43 626441.0 -47600.0 -0.36 -0.5583 -0.9965 3000976 BCB02_000188 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L13 compound treatment 596191.0 -40500.0 -0.3 666754.0 -7310.0 -0.06 -0.2484 -0.8254 3092772 BCB02_000189 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L14 compound treatment 541295.0 -95300.0 -0.7 682562.0 8500.0 0.06 -0.4474 -0.6389 3092773 BCB02_000190 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L15 compound treatment 601593.0 -35000.0 -0.26 705951.0 31900.0 0.24 -0.0099 -0.0282 3000977 BCB02_000191 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L16 compound treatment 755500.0 119000.0 0.87 627459.0 -46600.0 -0.35 0.3643 0.3881 3092774 BCB02_000192 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L17 mock treatment 529618.0 -107000.0 -0.78 671832.0 -2230.0 -0.02 -0.5654 -0.7222 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L18 mock treatment 523631.0 -113000.0 -0.83 592930.0 -81100.0 -0.62 -1.0202 -0.9896 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L19 mock treatment 599398.0 -37200.0 -0.27 613094.0 -61000.0 -0.46 -0.5201 -0.968 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L20 mock treatment 648294.0 11700.0 0.09 680959.0 6900.0 0.05 0.0973 0.9727 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L21 mock treatment 606384.0 -30300.0 -0.22 727992.0 53900.0 0.41 0.1332 0.2861 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L22 mock treatment 616022.0 -20600.0 -0.15 728751.0 54700.0 0.42 0.1871 0.4234 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L23 mock treatment 553552.0 -83100.0 -0.61 643350.0 -30700.0 -0.23 -0.5946 -0.9136 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 L24 mock treatment 623731.0 -12900.0 -0.09 785359.0 111000.0 0.85 0.5311 0.6243 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M01 compound treatment 647850.0 11200.0 0.08 650636.0 -23400.0 -0.18 -0.0679 -0.3464 3000978 BCB02_000193 CC1(C)[C@H]2C[C@H]1C=C(C2)C(O)C3C=CC4C(N3Nc5ccccc5F)C(=O)N(C4=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M02 compound treatment 627915.0 -8730.0 -0.06 760226.0 86200.0 0.65 0.4177 0.6352 3001047 BCB02_000194 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M03 compound treatment 706736.0 70100.0 0.51 640378.0 -33700.0 -0.26 0.1815 0.3168 3092775 BCB02_000195 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(I)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M04 compound treatment 639884.0 3240.0 0.02 715477.0 41400.0 0.31 0.2392 0.7582 3001048 BCB02_000196 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M05 compound treatment 593528.0 -43100.0 -0.32 812370.0 138000.0 1.05 0.52 0.474 3092776 BCB02_000197 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)[N+](=O)[O-])C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M06 compound treatment 605512.0 -31100.0 -0.23 720077.0 46000.0 0.35 0.0862 0.2066 3001049 BCB02_000198 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M07 compound treatment 676794.0 40200.0 0.29 866883.0 193000.0 1.46 1.2434 0.8323 3092777 BCB02_000199 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M08 compound treatment 544720.0 -91900.0 -0.67 722231.0 48200.0 0.37 -0.2166 -0.283 3092778 BCB02_000200 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M09 compound treatment 496369.0 -140000.0 -1.03 776942.0 103000.0 0.78 -0.1727 -0.1339 3001050 BCB02_000201 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(cc4)N(C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M10 compound treatment 348720.0 -288000.0 -2.11 434336.0 -240000.0 -1.82 -2.7766 -0.9974 3001168 BCB02_000202 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M11 compound treatment 729312.0 92700.0 0.68 802740.0 129000.0 0.98 1.1704 0.984 3092779 BCB02_000203 COc1ccc(NN2C3C(C=CC2C(O)c4cc(OC)c(OC)c(OC)c4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M12 compound treatment 565681.0 -71000.0 -0.52 764423.0 90400.0 0.69 0.1184 0.1376 3092780 BCB02_000204 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M13 compound treatment 548219.0 -88400.0 -0.65 818563.0 145000.0 1.1 0.319 0.2504 3001169 BCB02_000205 COc1ccc(NN2C3C(C=CC2C(O)C4=CC[C@H](CC4)C(=C)C)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M14 compound treatment 548994.0 -87600.0 -0.64 559913.0 -114000.0 -0.87 -1.0664 -0.9889 3092781 BCB02_000206 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M15 compound treatment 700085.0 63400.0 0.46 867974.0 194000.0 1.47 1.3697 0.8869 3001170 BCB02_000207 COc1ccc(NN2C3C(C=CC2C(O)c4ccco4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M16 mock treatment 849030.0 212000.0 1.55 817014.0 143000.0 1.09 1.8662 0.9847 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M17 mock treatment 623075.0 -13600.0 -0.1 684442.0 10400.0 0.08 -0.0144 -0.1136 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M18 mock treatment 720850.0 84200.0 0.62 693179.0 19100.0 0.15 0.5381 0.8505 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M19 mock treatment 658160.0 21500.0 0.16 757166.0 83100.0 0.63 0.5577 0.8571 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M20 mock treatment 622475.0 -14200.0 -0.1 719234.0 45200.0 0.34 0.1694 0.4726 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M21 mock treatment 819341.0 183000.0 1.34 725199.0 51100.0 0.39 1.2195 0.8764 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M22 mock treatment 653467.0 16800.0 0.12 745346.0 71300.0 0.54 0.4699 0.8462 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M23 mock treatment 644089.0 7450.0 0.05 638343.0 -35700.0 -0.27 -0.1534 -0.5541 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 M24 mock treatment 613906.0 -22700.0 -0.17 719809.0 45700.0 0.35 0.1282 0.3327 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N01 compound treatment 613213.0 -23400.0 -0.17 717801.0 43700.0 0.33 0.1138 0.3044 3092782 BCB02_000208 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N02 compound treatment 665600.0 29000.0 0.21 776384.0 102000.0 0.78 0.6994 0.8681 3092783 BCB02_000209 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N03 compound treatment 639005.0 2360.0 0.02 964975.0 291000.0 2.21 1.5749 0.7126 3001171 BCB02_000210 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N04 compound treatment 689347.0 52700.0 0.39 876403.0 202000.0 1.54 1.3595 0.8579 3092784 BCB02_000211 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N05 compound treatment 638739.0 2100.0 0.02 821923.0 148000.0 1.12 0.8051 0.7167 3001172 BCB02_000212 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc([Ac])cc2)c3ccc([Ac])cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N06 compound treatment 589785.0 -46900.0 -0.34 827133.0 153000.0 1.16 0.58 0.4784 3092785 BCB02_000213 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N07 compound treatment 634580.0 -2060.0 -0.02 854162.0 180000.0 1.37 0.9568 0.6993 3092786 BCB02_000214 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N08 compound treatment 538674.0 -98000.0 -0.72 689877.0 15800.0 0.12 -0.4216 -0.5804 3001173 BCB02_000215 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N09 compound treatment 540916.0 -95700.0 -0.7 814151.0 140000.0 1.06 0.2575 0.2022 3092787 BCB02_000216 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N10 compound treatment 532599.0 -104000.0 -0.76 822762.0 149000.0 1.13 0.2608 0.1915 3001174 BCB02_000217 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N11 compound treatment 698759.0 62100.0 0.45 755991.0 81900.0 0.62 0.7613 0.988 3092788 BCB02_000218 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N12 compound treatment 629730.0 -6910.0 -0.05 702678.0 28600.0 0.22 0.118 0.5286 3092789 BCB02_000219 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N13 compound treatment 405230.0 -231000.0 -1.69 490637.0 -183000.0 -1.39 -2.182 -0.9953 3001175 BCB02_000220 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N14 compound treatment 568640.0 -68000.0 -0.5 631392.0 -42700.0 -0.32 -0.5809 -0.9785 3092790 BCB02_000221 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N15 compound treatment 746686.0 110000.0 0.8 701044.0 27000.0 0.2 0.714 0.8598 3001176 BCB02_000222 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N16 mock treatment 599250.0 -37400.0 -0.27 774443.0 100000.0 0.76 0.3459 0.4269 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N17 mock treatment 760035.0 123000.0 0.9 673450.0 -612.0 0.0 0.6348 0.7035 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N18 mock treatment 696377.0 59700.0 0.44 721214.0 47200.0 0.36 0.5622 0.9951 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N19 mock treatment 665311.0 28700.0 0.21 744710.0 70600.0 0.54 0.5278 0.9159 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N20 mock treatment 668202.0 31600.0 0.23 787736.0 114000.0 0.86 0.7738 0.8657 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N21 mock treatment 739461.0 103000.0 0.75 745675.0 71600.0 0.54 0.9164 0.9874 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N22 mock treatment 724100.0 87500.0 0.64 729722.0 55700.0 0.42 0.7513 0.9798 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N23 mock treatment 684635.0 48000.0 0.35 694538.0 20500.0 0.16 0.3582 0.933 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 N24 mock treatment 646233.0 9590.0 0.07 705104.0 31000.0 0.24 0.2163 0.8794 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O01 compound treatment 638524.0 1880.0 0.01 750094.0 76000.0 0.58 0.4182 0.7238 3092791 BCB02_000223 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccc(Br)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O02 compound treatment 658527.0 21900.0 0.16 716330.0 42300.0 0.32 0.3402 0.9483 3001177 BCB02_000224 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O03 compound treatment 629909.0 -6730.0 -0.05 743179.0 69100.0 0.53 0.3365 0.638 3092792 BCB02_000225 COc1ccc(NN2C3C(C=CC2C(O)c4ccc(OC)c(OCc5ccccc5)c4)C(=O)N(C6CCCCC6)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O04 compound treatment 628082.0 -8560.0 -0.06 733973.0 59900.0 0.46 0.2776 0.6042 3001178 BCB02_000226 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O05 compound treatment 718722.0 82100.0 0.6 863677.0 190000.0 1.44 1.443 0.9247 3092860 BCB02_000227 COc1ccc(NN2C3C(C=CC2C(O)c4ccccn4)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O06 compound treatment 566687.0 -70000.0 -0.51 818276.0 144000.0 1.1 0.4129 0.3415 3001179 BCB02_000228 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O07 compound treatment 638323.0 1680.0 0.01 816244.0 142000.0 1.08 0.7725 0.7151 3092861 BCB02_000229 CCOc1cc(ccc1O)C(O)C2C=CC3C(N2Nc4ccc(OC)cc4)C(=O)N(C5CCCCC5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O08 compound treatment 587534.0 -49100.0 -0.36 690149.0 16100.0 0.12 -0.1675 -0.4416 3001245 BCB02_000230 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O09 compound treatment 736661.0 100000.0 0.73 733526.0 59500.0 0.45 0.8366 0.9732 3092862 BCB02_000231 COc1ccc(NN2C3C(C=CC2C(O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O10 compound treatment 575903.0 -60700.0 -0.44 752876.0 78800.0 0.6 0.1093 0.1466 3001246 BCB02_000232 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O11 compound treatment 713253.0 76600.0 0.56 774132.0 100000.0 0.76 0.9337 0.9887 3092863 BCB02_000233 Cc1ccc(NN2C3C(C=CC2C(O)c4c(F)cccc4Cl)C(=O)N(C5CCCCC5)C3=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O12 compound treatment 710389.0 73700.0 0.54 803863.0 130000.0 0.99 1.0786 0.9597 3001247 BCB02_000234 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O13 compound treatment 664412.0 27800.0 0.2 819612.0 146000.0 1.11 0.9255 0.8232 3092864 BCB02_000235 OC(C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O14 compound treatment 676845.0 40200.0 0.29 733520.0 59500.0 0.45 0.5273 0.9784 3001248 BCB02_000236 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O15 compound treatment 706762.0 70100.0 0.51 810221.0 136000.0 1.03 1.094 0.9476 3092865 BCB02_000237 CCC(CC)C(O)C1C=CC2C(N1Nc3ccccc3F)C(=O)N(C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O16 mock treatment 612271.0 -24400.0 -0.18 653611.0 -20500.0 -0.16 -0.2359 -0.9977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O17 mock treatment 665346.0 28700.0 0.21 719496.0 45400.0 0.35 0.3925 0.9716 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O18 mock treatment 654596.0 18000.0 0.13 598959.0 -75100.0 -0.57 -0.3106 -0.5305 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O19 mock treatment 671547.0 34900.0 0.26 746999.0 72900.0 0.55 0.5723 0.9381 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O20 mock treatment 667334.0 30700.0 0.22 701343.0 27300.0 0.21 0.3053 0.9992 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O21 mock treatment 659689.0 23000.0 0.17 724864.0 50800.0 0.39 0.3921 0.931 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O22 mock treatment 672630.0 36000.0 0.26 713878.0 39800.0 0.3 0.4 0.9976 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O23 mock treatment 646499.0 9860.0 0.07 630586.0 -43500.0 -0.33 -0.1826 -0.5401 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 O24 mock treatment 676498.0 39900.0 0.29 693892.0 19800.0 0.15 0.3126 0.9528 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P01 compound treatment 685928.0 49300.0 0.36 762404.0 88300.0 0.67 0.7294 0.9575 3001249 BCB02_000238 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P02 compound treatment 719338.0 82700.0 0.6 737606.0 63500.0 0.48 0.769 0.9938 3092866 BCB02_000239 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P03 compound treatment 650375.0 13700.0 0.1 825715.0 152000.0 1.15 0.8857 0.7658 3001250 BCB02_000240 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P04 compound treatment 634791.0 -1850.0 -0.01 851844.0 178000.0 1.35 0.9454 0.7 3092867 BCB02_000241 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P05 compound treatment 729076.0 92400.0 0.68 772574.0 98500.0 0.75 1.0072 0.9987 3001251 BCB02_000242 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P06 compound treatment 629611.0 -7030.0 -0.05 708726.0 34700.0 0.26 0.1499 0.5585 3092868 BCB02_000243 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P07 compound treatment 586342.0 -50300.0 -0.37 669110.0 -4950.0 -0.04 -0.2867 -0.7754 3001252 BCB02_000244 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P08 compound treatment 614812.0 -21800.0 -0.16 780717.0 107000.0 0.81 0.46 0.5571 3092869 BCB02_000245 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P09 compound treatment 686077.0 49400.0 0.36 815042.0 141000.0 1.07 1.0129 0.8961 3001253 BCB02_000246 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P10 compound treatment 730796.0 94200.0 0.69 827929.0 154000.0 1.17 1.3134 0.9682 3092870 BCB02_000247 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P11 compound treatment 772782.0 136000.0 1.0 727161.0 53100.0 0.4 0.9892 0.9209 3001254 BCB02_000248 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P12 compound treatment 613171.0 -23500.0 -0.17 602038.0 -72000.0 -0.55 -0.5083 -0.8863 3092871 BCB02_000249 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P13 compound treatment 684964.0 48300.0 0.35 625367.0 -48700.0 -0.37 -0.0117 -0.0229 3001255 BCB02_000250 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P14 compound treatment 671235.0 34600.0 0.25 664282.0 -9780.0 -0.07 0.1264 0.4792 3092774 BCB02_000251 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P15 compound treatment 676708.0 40100.0 0.29 691928.0 17900.0 0.14 0.3032 0.9388 3092872 BCB02_000252 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P16 mock treatment 781461.0 145000.0 1.06 650696.0 -23400.0 -0.18 0.6234 0.5805 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P17 mock treatment 697635.0 61000.0 0.45 680682.0 6620.0 0.05 0.351 0.7819 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P18 mock treatment 679659.0 43000.0 0.31 757205.0 83100.0 0.63 0.6691 0.9482 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P19 mock treatment 676754.0 40100.0 0.29 662932.0 -11100.0 -0.08 0.1476 0.4836 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P20 mock treatment 746660.0 110000.0 0.8 825418.0 151000.0 1.15 1.382 0.9848 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P21 mock treatment 793520.0 157000.0 1.15 683900.0 9840.0 0.07 0.8641 0.7516 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P22 mock treatment 692289.0 55600.0 0.41 677784.0 3720.0 0.03 0.3078 0.7544 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P23 mock treatment 693079.0 56400.0 0.41 692317.0 18300.0 0.14 0.3899 0.8955 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2088 P24 mock treatment 720087.0 83400.0 0.61 697491.0 23400.0 0.18 0.5574 0.8768 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A01 compound treatment 564948.0 -90100.0 -0.66 586421.0 -96200.0 -0.73 -0.9828 -0.9987 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A02 compound treatment 626886.0 -28200.0 -0.21 500674.0 -182000.0 -1.38 -1.1231 -0.8036 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A03 compound treatment 599509.0 -55500.0 -0.41 678800.0 -3840.0 -0.03 -0.3078 -0.7559 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A04 compound treatment 572963.0 -82100.0 -0.6 611760.0 -70900.0 -0.54 -0.8052 -0.9985 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A05 compound treatment 662840.0 7790.0 0.06 664232.0 -18400.0 -0.14 -0.0586 -0.3881 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A06 compound treatment 642856.0 -12200.0 -0.09 740806.0 58200.0 0.44 0.2494 0.5532 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A07 compound treatment 593688.0 -61400.0 -0.45 657179.0 -25500.0 -0.19 -0.4541 -0.9292 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A08 compound treatment 661272.0 6220.0 0.05 677159.0 -5480.0 -0.04 0.0027 0.0445 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A09 compound treatment 596299.0 -58800.0 -0.43 664650.0 -18000.0 -0.14 -0.4004 -0.8882 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A10 compound treatment 593063.0 -62000.0 -0.45 622976.0 -59700.0 -0.45 -0.641 -1.0 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A11 compound treatment 811332.0 156000.0 1.14 696068.0 13400.0 0.1 0.8803 0.7672 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A12 compound treatment 661000.0 5950.0 0.04 581033.0 -102000.0 -0.77 -0.515 -0.6662 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A13 mock treatment 609887.0 -45200.0 -0.33 622820.0 -59800.0 -0.45 -0.5549 -0.9877 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A14 mock treatment 648392.0 -6660.0 -0.05 750626.0 68000.0 0.52 0.3308 0.6376 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A15 compound treatment 508888.0 -146000.0 -1.07 423718.0 -259000.0 -1.97 -2.1467 -0.9589 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A16 compound treatment 618747.0 -36300.0 -0.27 753287.0 70700.0 0.54 0.1918 0.3203 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A17 compound treatment 654708.0 -343.0 0.0 688307.0 5670.0 0.04 0.0287 0.6648 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A18 compound treatment 681182.0 26100.0 0.19 575480.0 -107000.0 -0.81 -0.4405 -0.5268 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A19 compound treatment 593446.0 -61600.0 -0.45 657147.0 -25500.0 -0.19 -0.4555 -0.9289 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A20 compound treatment 447571.0 -207000.0 -1.52 552131.0 -131000.0 -0.99 -1.774 -0.9787 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A21 compound treatment 556551.0 -98500.0 -0.72 599766.0 -82900.0 -0.63 -0.9545 -0.9977 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A22 compound treatment 673070.0 18000.0 0.13 758740.0 76100.0 0.58 0.502 0.8466 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A23 compound treatment 671373.0 16300.0 0.12 572087.0 -111000.0 -0.84 -0.5094 -0.6006 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 A24 compound treatment 510610.0 -144000.0 -1.06 570429.0 -112000.0 -0.85 -1.3497 -0.9943 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B01 compound treatment 610668.0 -44400.0 -0.32 770349.0 87700.0 0.67 0.2417 0.326 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B02 compound treatment 728352.0 73300.0 0.54 703866.0 21200.0 0.16 0.4931 0.8808 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B03 compound treatment 642059.0 -13000.0 -0.1 541299.0 -141000.0 -1.07 -0.8264 -0.7667 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B04 compound treatment 621433.0 -33600.0 -0.25 662622.0 -20000.0 -0.15 -0.2814 -0.9733 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B05 compound treatment 645901.0 -9150.0 -0.07 624218.0 -58400.0 -0.44 -0.3611 -0.8046 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B06 compound treatment 615751.0 -39300.0 -0.29 674973.0 -7660.0 -0.06 -0.2444 -0.8334 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B07 compound treatment 610852.0 -44200.0 -0.32 697037.0 14400.0 0.11 -0.1512 -0.4431 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B08 compound treatment 477171.0 -178000.0 -1.3 598403.0 -84200.0 -0.64 -1.3723 -0.9466 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B09 compound treatment 572742.0 -82300.0 -0.6 670543.0 -12100.0 -0.09 -0.4906 -0.8057 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B10 compound treatment 623276.0 -31800.0 -0.23 580067.0 -103000.0 -0.78 -0.7153 -0.8797 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B11 compound treatment 496502.0 -159000.0 -1.16 429597.0 -253000.0 -1.92 -2.1791 -0.9707 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B12 compound treatment 634203.0 -20800.0 -0.15 685998.0 3360.0 0.03 -0.0898 -0.5806 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B13 mock treatment 643147.0 -11900.0 -0.09 802879.0 120000.0 0.91 0.5844 0.6368 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B14 mock treatment 699407.0 44400.0 0.32 679801.0 -2840.0 -0.02 0.2141 0.6587 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B15 compound treatment 697834.0 42800.0 0.31 681558.0 -1080.0 -0.01 0.2154 0.6883 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B16 compound treatment 562755.0 -92300.0 -0.67 659212.0 -23400.0 -0.18 -0.6031 -0.864 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B17 compound treatment 166810.0 -488000.0 -3.57 153764.0 -529000.0 -4.02 -5.3657 -0.9983 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B18 compound treatment 681383.0 26300.0 0.19 663336.0 -19300.0 -0.15 0.0325 0.1342 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B19 compound treatment 533678.0 -121000.0 -0.89 619205.0 -63400.0 -0.48 -0.9684 -0.9588 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B20 compound treatment 635332.0 -19700.0 -0.14 653602.0 -29000.0 -0.22 -0.2579 -0.9788 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B21 compound treatment 606150.0 -48900.0 -0.36 624179.0 -58500.0 -0.44 -0.5669 -0.9942 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B22 compound treatment 568630.0 -86400.0 -0.63 616886.0 -65800.0 -0.5 -0.8001 -0.9932 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B23 compound treatment 627636.0 -27400.0 -0.2 721993.0 39400.0 0.3 0.0696 0.1935 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 B24 compound treatment 569232.0 -85800.0 -0.63 587143.0 -95500.0 -0.73 -0.9567 -0.9974 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C01 compound treatment 507001.0 -148000.0 -1.08 482677.0 -200000.0 -1.52 -1.8397 -0.9862 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C02 compound treatment 603375.0 -51700.0 -0.38 654971.0 -27700.0 -0.21 -0.4158 -0.9616 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C03 compound treatment 615474.0 -39600.0 -0.29 710059.0 27400.0 0.21 -0.0574 -0.1608 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C04 compound treatment 632043.0 -23000.0 -0.17 628353.0 -54300.0 -0.41 -0.4106 -0.9218 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C05 compound treatment 584147.0 -70900.0 -0.52 647797.0 -34800.0 -0.26 -0.5538 -0.9513 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C06 compound treatment 677765.0 22700.0 0.17 770416.0 87800.0 0.67 0.589 0.8571 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C07 compound treatment 613395.0 -41700.0 -0.3 643904.0 -38700.0 -0.29 -0.4235 -0.9998 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C08 compound treatment 709963.0 54900.0 0.4 660315.0 -22300.0 -0.17 0.1641 0.3763 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C09 compound treatment 672855.0 17800.0 0.13 723032.0 40400.0 0.31 0.3091 0.9271 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C10 compound treatment 563682.0 -91400.0 -0.67 593069.0 -89600.0 -0.68 -0.9536 -1.0 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C11 mock treatment 575428.0 -79600.0 -0.58 606822.0 -75800.0 -0.58 -0.819 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C12 mock treatment 657924.0 2870.0 0.02 660520.0 -22100.0 -0.17 -0.1039 -0.6139 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C13 compound treatment 152027.0 -503000.0 -3.68 154329.0 -528000.0 -4.01 -5.4391 -0.9991 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C14 compound treatment 736958.0 81900.0 0.6 723620.0 41000.0 0.31 0.6437 0.9535 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C15 mock treatment 629139.0 -25900.0 -0.19 733782.0 51100.0 0.39 0.1407 0.3256 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C16 mock treatment 698403.0 43400.0 0.32 717121.0 34500.0 0.26 0.4094 0.9955 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C17 compound treatment 193750.0 -461000.0 -3.37 193287.0 -489000.0 -3.72 -5.0141 -0.9988 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C18 compound treatment 713714.0 58700.0 0.43 637186.0 -45500.0 -0.35 0.0592 0.1075 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C19 compound treatment 514248.0 -141000.0 -1.03 503870.0 -179000.0 -1.36 -1.6884 -0.9907 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C20 compound treatment 713686.0 58600.0 0.43 754335.0 71700.0 0.54 0.6884 0.993 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C21 compound treatment 674353.0 19300.0 0.14 677043.0 -5590.0 -0.04 0.0698 0.4733 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C22 compound treatment 632303.0 -22700.0 -0.17 655082.0 -27600.0 -0.21 -0.2656 -0.9935 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C23 compound treatment 584024.0 -71000.0 -0.52 652766.0 -29900.0 -0.23 -0.5277 -0.931 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 C24 compound treatment 475078.0 -180000.0 -1.32 429137.0 -253000.0 -1.93 -2.2924 -0.9828 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D01 compound treatment 765443.0 110000.0 0.81 677911.0 -4730.0 -0.04 0.5455 0.675 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D02 compound treatment 777277.0 122000.0 0.89 694670.0 12000.0 0.09 0.6967 0.7754 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D03 compound treatment 616727.0 -38300.0 -0.28 671567.0 -11100.0 -0.08 -0.2576 -0.8805 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D04 compound treatment 431288.0 -224000.0 -1.64 477367.0 -205000.0 -1.56 -2.2598 -0.9997 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D05 compound treatment 616491.0 -38600.0 -0.28 631476.0 -51200.0 -0.39 -0.4742 -0.9876 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D06 compound treatment 503464.0 -152000.0 -1.11 502922.0 -180000.0 -1.37 -1.7493 -0.9947 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D07 compound treatment 618160.0 -36900.0 -0.27 654127.0 -28500.0 -0.22 -0.3439 -0.9941 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D08 compound treatment 548988.0 -106000.0 -0.78 576628.0 -106000.0 -0.81 -1.1179 -0.9998 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D09 compound treatment 186573.0 -468000.0 -3.43 262359.0 -420000.0 -3.19 -4.6802 -0.9994 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D10 compound treatment 656048.0 997.0 0.01 587872.0 -94800.0 -0.72 -0.5039 -0.6999 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D11 mock treatment 634850.0 -20200.0 -0.15 601783.0 -80900.0 -0.61 -0.5388 -0.8529 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D12 mock treatment 634338.0 -20700.0 -0.15 689087.0 6450.0 0.05 -0.0725 -0.4551 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D13 compound treatment 457590.0 -197000.0 -1.44 515596.0 -167000.0 -1.27 -1.9184 -0.9979 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D14 compound treatment 691575.0 36500.0 0.27 644819.0 -37800.0 -0.29 -0.0143 -0.0364 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D15 mock treatment 637804.0 -17200.0 -0.13 602175.0 -80500.0 -0.61 -0.5214 -0.8354 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D16 mock treatment 693588.0 38500.0 0.28 680763.0 -1870.0 -0.01 0.1892 0.6705 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D17 compound treatment 632600.0 -22500.0 -0.16 538332.0 -144000.0 -1.1 -0.8913 -0.804 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D18 compound treatment 604735.0 -50300.0 -0.37 594328.0 -88300.0 -0.67 -0.7346 -0.96 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D19 compound treatment 621372.0 -33700.0 -0.25 699696.0 17100.0 0.13 -0.0825 -0.2965 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D20 compound treatment 745877.0 90800.0 0.66 660935.0 -21700.0 -0.16 0.3531 0.5159 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D21 compound treatment 576554.0 -78500.0 -0.57 556533.0 -126000.0 -0.96 -1.0833 -0.97 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D22 compound treatment 707177.0 52100.0 0.38 555665.0 -127000.0 -0.96 -0.4125 -0.3977 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D23 compound treatment 585272.0 -69800.0 -0.51 546128.0 -137000.0 -1.04 -1.0941 -0.9467 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 D24 compound treatment 468360.0 -187000.0 -1.37 448567.0 -234000.0 -1.78 -2.2228 -0.9915 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E01 mock treatment 673239.0 18200.0 0.13 689018.0 6380.0 0.05 0.1283 0.9065 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E02 mock treatment 635483.0 -19600.0 -0.14 664047.0 -18600.0 -0.14 -0.201 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E03 compound treatment 652499.0 -2550.0 -0.02 685772.0 3140.0 0.02 0.0036 0.1205 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E04 compound treatment 520151.0 -135000.0 -0.99 599592.0 -83000.0 -0.63 -1.1437 -0.9767 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E05 compound treatment 637454.0 -17600.0 -0.13 645816.0 -36800.0 -0.28 -0.2888 -0.9379 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E06 compound treatment 684095.0 29000.0 0.21 703255.0 20600.0 0.16 0.2609 0.9888 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E07 compound treatment 138300.0 -517000.0 -3.78 139062.0 -544000.0 -4.13 -5.5921 -0.999 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E08 compound treatment 493380.0 -162000.0 -1.18 597975.0 -84700.0 -0.64 -1.2908 -0.959 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E09 mock treatment 588710.0 -66300.0 -0.49 573407.0 -109000.0 -0.83 -0.9298 -0.9673 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E10 mock treatment 610086.0 -45000.0 -0.33 683841.0 1200.0 0.01 -0.2261 -0.6872 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E11 compound treatment 607147.0 -47900.0 -0.35 656622.0 -26000.0 -0.2 -0.3875 -0.9633 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E12 compound treatment 643022.0 -12000.0 -0.09 681659.0 -978.0 -0.01 -0.0675 -0.7641 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E13 compound treatment 149252.0 -506000.0 -3.7 150371.0 -532000.0 -4.04 -5.4748 -0.999 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E14 compound treatment 602232.0 -52800.0 -0.39 681220.0 -1420.0 -0.01 -0.2807 -0.7265 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E15 compound treatment 419862.0 -235000.0 -1.72 469330.0 -213000.0 -1.62 -2.362 -0.9996 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E16 compound treatment 755707.0 101000.0 0.74 644773.0 -37900.0 -0.29 0.3171 0.4013 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E17 mock treatment 584519.0 -70500.0 -0.52 632082.0 -50600.0 -0.38 -0.6363 -0.9895 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E18 mock treatment 705835.0 50800.0 0.37 701810.0 19200.0 0.15 0.3656 0.9165 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E19 compound treatment 687193.0 32100.0 0.24 667544.0 -15100.0 -0.11 0.0851 0.3255 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E20 compound treatment 769231.0 114000.0 0.84 742226.0 59600.0 0.45 0.9105 0.9586 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E21 compound treatment 702116.0 47100.0 0.34 739098.0 56500.0 0.43 0.5467 0.994 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E22 compound treatment 737697.0 82600.0 0.6 635810.0 -46800.0 -0.36 0.1758 0.2507 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E23 compound treatment 621113.0 -33900.0 -0.25 624012.0 -58600.0 -0.45 -0.4904 -0.9619 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 E24 compound treatment 438652.0 -216000.0 -1.58 366765.0 -316000.0 -2.4 -2.8158 -0.9796 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F01 mock treatment 734603.0 79600.0 0.58 680342.0 -2290.0 -0.02 0.399 0.6856 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F02 mock treatment 546096.0 -109000.0 -0.8 636416.0 -46200.0 -0.35 -0.8117 -0.9322 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F03 compound treatment 579125.0 -75900.0 -0.56 657609.0 -25000.0 -0.19 -0.5271 -0.898 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F04 compound treatment 620904.0 -34100.0 -0.25 641322.0 -41300.0 -0.31 -0.3985 -0.9936 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F05 compound treatment 456839.0 -198000.0 -1.45 524961.0 -158000.0 -1.2 -1.872 -0.9955 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F06 compound treatment 617495.0 -37600.0 -0.27 733752.0 51100.0 0.39 0.0804 0.169 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F07 compound treatment 543358.0 -112000.0 -0.82 693840.0 11200.0 0.09 -0.5174 -0.63 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F08 compound treatment 680494.0 25400.0 0.19 668993.0 -13600.0 -0.1 0.0583 0.2736 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F09 mock treatment 638702.0 -16300.0 -0.12 751067.0 68400.0 0.52 0.283 0.5306 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F10 mock treatment 627782.0 -27300.0 -0.2 696896.0 14300.0 0.11 -0.0644 -0.2838 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F11 compound treatment 377365.0 -278000.0 -2.03 385863.0 -297000.0 -2.25 -3.0301 -0.9986 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F12 compound treatment 599858.0 -55200.0 -0.4 622236.0 -60400.0 -0.46 -0.6099 -0.998 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F13 compound treatment 232024.0 -423000.0 -3.09 277063.0 -406000.0 -3.08 -4.3662 -1.0 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F14 compound treatment 577217.0 -77800.0 -0.57 634814.0 -47800.0 -0.36 -0.6594 -0.9765 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F15 compound treatment 378151.0 -277000.0 -2.02 402645.0 -280000.0 -2.13 -2.9359 -0.9997 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F16 compound treatment 545698.0 -109000.0 -0.8 585380.0 -97300.0 -0.74 -1.0879 -0.9992 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F17 mock treatment 581651.0 -73400.0 -0.54 670731.0 -11900.0 -0.09 -0.4435 -0.8148 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F18 mock treatment 569413.0 -85600.0 -0.63 618591.0 -64000.0 -0.49 -0.7869 -0.9922 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F19 compound treatment 675306.0 20300.0 0.15 652503.0 -30100.0 -0.23 -0.0571 -0.2095 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F20 compound treatment 717620.0 62600.0 0.46 721366.0 38700.0 0.29 0.5316 0.9772 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F21 compound treatment 692444.0 37400.0 0.27 740463.0 57800.0 0.44 0.504 0.974 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F22 compound treatment 661654.0 6600.0 0.05 692655.0 10000.0 0.08 0.088 0.9759 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F23 compound treatment 718836.0 63800.0 0.47 674819.0 -7820.0 -0.06 0.2878 0.6121 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 F24 compound treatment 710219.0 55200.0 0.4 589584.0 -93100.0 -0.71 -0.2146 -0.2636 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G01 compound treatment 654718.0 -333.0 0.0 556937.0 -126000.0 -0.95 -0.6769 -0.7089 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G02 compound treatment 598538.0 -56500.0 -0.41 622737.0 -59900.0 -0.46 -0.614 -0.9988 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G03 mock treatment 524228.0 -131000.0 -0.96 662320.0 -20300.0 -0.15 -0.7856 -0.8107 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G04 mock treatment 657027.0 1980.0 0.01 639311.0 -43300.0 -0.33 -0.2225 -0.6754 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G05 compound treatment 582465.0 -72600.0 -0.53 711172.0 28500.0 0.22 -0.2221 -0.3873 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G06 compound treatment 630830.0 -24200.0 -0.18 692436.0 9800.0 0.07 -0.0726 -0.3779 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G07 compound treatment 600704.0 -54300.0 -0.4 640178.0 -42500.0 -0.32 -0.5091 -0.9946 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G08 compound treatment 720453.0 65400.0 0.48 764951.0 82300.0 0.63 0.7804 0.9912 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G09 compound treatment 686340.0 31300.0 0.23 740015.0 57400.0 0.44 0.47 0.9547 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G10 compound treatment 609637.0 -45400.0 -0.33 707005.0 24400.0 0.19 -0.1039 -0.2734 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G11 compound treatment 574239.0 -80800.0 -0.59 693365.0 10700.0 0.08 -0.3603 -0.6039 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G12 compound treatment 454164.0 -201000.0 -1.47 478606.0 -204000.0 -1.55 -2.1348 -0.9996 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G13 compound treatment 143015.0 -512000.0 -3.74 144529.0 -538000.0 -4.09 -5.5384 -0.999 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G14 compound treatment 614935.0 -40100.0 -0.29 807349.0 125000.0 0.95 0.4625 0.4663 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G15 compound treatment 611986.0 -43100.0 -0.31 741992.0 59400.0 0.45 0.0961 0.1748 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G16 compound treatment 467992.0 -187000.0 -1.37 501531.0 -181000.0 -1.38 -1.9402 -1.0 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G17 compound treatment 617370.0 -37700.0 -0.28 662768.0 -19900.0 -0.15 -0.3016 -0.9599 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G18 compound treatment 676790.0 21700.0 0.16 670725.0 -11900.0 -0.09 0.0484 0.2647 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G19 mock treatment 651705.0 -3350.0 -0.02 662938.0 -19700.0 -0.15 -0.1231 -0.8119 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G20 mock treatment 677328.0 22300.0 0.16 593595.0 -89000.0 -0.68 -0.3631 -0.5219 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G21 compound treatment 723071.0 68000.0 0.5 672270.0 -10400.0 -0.08 0.2961 0.5878 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G22 compound treatment 588155.0 -66900.0 -0.49 606171.0 -76500.0 -0.58 -0.7567 -0.9964 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G23 compound treatment 701563.0 46500.0 0.34 603052.0 -79600.0 -0.6 -0.187 -0.2695 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 G24 compound treatment 590102.0 -64900.0 -0.47 516137.0 -166000.0 -1.26 -1.2303 -0.9106 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H01 compound treatment 680139.0 25100.0 0.18 718754.0 36100.0 0.27 0.3237 0.9809 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H02 compound treatment 743315.0 88300.0 0.65 652272.0 -30400.0 -0.23 0.2933 0.4279 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H03 mock treatment 759890.0 105000.0 0.77 639272.0 -43400.0 -0.33 0.3092 0.3705 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H04 mock treatment 591957.0 -63100.0 -0.46 657026.0 -25600.0 -0.19 -0.4638 -0.9263 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H05 compound treatment 536656.0 -118000.0 -0.87 664943.0 -17700.0 -0.13 -0.7073 -0.8072 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H06 compound treatment 595006.0 -60000.0 -0.44 691834.0 9200.0 0.07 -0.2611 -0.5872 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H07 compound treatment 473054.0 -182000.0 -1.33 553642.0 -129000.0 -0.98 -1.6341 -0.9887 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H08 compound treatment 668102.0 13100.0 0.1 730387.0 47800.0 0.36 0.324 0.8638 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H09 compound treatment 459669.0 -195000.0 -1.43 531995.0 -151000.0 -1.14 -1.8196 -0.9939 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H10 compound treatment 643613.0 -11400.0 -0.08 525612.0 -157000.0 -1.19 -0.9026 -0.7548 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H11 compound treatment 699024.0 44000.0 0.32 571416.0 -111000.0 -0.84 -0.3701 -0.4093 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H12 compound treatment 419604.0 -235000.0 -1.72 442411.0 -240000.0 -1.82 -2.508 -0.9996 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H13 compound treatment 452844.0 -202000.0 -1.48 439044.0 -244000.0 -1.85 -2.3542 -0.9938 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H14 compound treatment 204598.0 -450000.0 -3.29 254233.0 -428000.0 -3.25 -4.6306 -1.0 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H15 compound treatment 506003.0 -149000.0 -1.09 487272.0 -195000.0 -1.48 -1.8202 -0.9885 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H16 compound treatment 725865.0 70800.0 0.52 802331.0 120000.0 0.91 1.0092 0.9644 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H17 compound treatment 568884.0 -86200.0 -0.63 740252.0 57600.0 0.44 -0.1361 -0.1774 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H18 compound treatment 672644.0 17600.0 0.13 662467.0 -20200.0 -0.15 -0.0174 -0.0868 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H19 mock treatment 639340.0 -15700.0 -0.11 676173.0 -6460.0 -0.05 -0.116 -0.9281 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H20 mock treatment 603065.0 -52000.0 -0.38 619005.0 -63600.0 -0.48 -0.6106 -0.9929 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H21 compound treatment 607435.0 -47600.0 -0.35 586408.0 -96200.0 -0.73 -0.7631 -0.9425 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H22 compound treatment 651523.0 -3530.0 -0.03 629020.0 -53600.0 -0.41 -0.3063 -0.7504 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H23 compound treatment 682135.0 27100.0 0.2 529861.0 -153000.0 -1.16 -0.6806 -0.5781 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 H24 compound treatment 494771.0 -160000.0 -1.17 376457.0 -306000.0 -2.33 -2.4735 -0.9497 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I01 compound treatment 678071.0 23000.0 0.17 672842.0 -9790.0 -0.07 0.0664 0.3609 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I02 compound treatment 649828.0 -5220.0 -0.04 570524.0 -112000.0 -0.85 -0.6292 -0.7381 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I03 compound treatment 632309.0 -22700.0 -0.17 667641.0 -15000.0 -0.11 -0.1982 -0.983 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I04 compound treatment 636668.0 -18400.0 -0.13 757399.0 74800.0 0.57 0.3065 0.5252 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I05 mock treatment 563889.0 -91200.0 -0.67 746452.0 63800.0 0.48 -0.1286 -0.156 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I06 mock treatment 604462.0 -50600.0 -0.37 674562.0 -8070.0 -0.06 -0.305 -0.8132 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I07 compound treatment 662271.0 7220.0 0.05 665426.0 -17200.0 -0.13 -0.0551 -0.3909 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I08 compound treatment 714059.0 59000.0 0.43 790686.0 108000.0 0.82 0.8856 0.9549 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I09 compound treatment 659644.0 4590.0 0.03 736262.0 53600.0 0.41 0.3118 0.7628 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I10 compound treatment 667381.0 12300.0 0.09 762261.0 79600.0 0.6 0.4915 0.8036 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I11 compound treatment 583405.0 -71600.0 -0.52 792175.0 110000.0 0.83 0.2179 0.2216 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I12 compound treatment 759273.0 104000.0 0.76 657069.0 -25600.0 -0.19 0.4016 0.5106 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I13 compound treatment 684154.0 29100.0 0.21 725967.0 43300.0 0.33 0.3833 0.9777 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I14 compound treatment 651836.0 -3210.0 -0.02 648537.0 -34100.0 -0.26 -0.1998 -0.7681 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I15 compound treatment 679861.0 24800.0 0.18 811638.0 129000.0 0.98 0.8213 0.824 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I16 compound treatment 538960.0 -116000.0 -0.85 600113.0 -82500.0 -0.63 -1.0436 -0.9889 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I17 compound treatment 667703.0 12700.0 0.09 711006.0 28400.0 0.22 0.2178 0.9287 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I18 compound treatment 681707.0 26700.0 0.19 759233.0 76600.0 0.58 0.5493 0.8951 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I19 compound treatment 622863.0 -32200.0 -0.24 692902.0 10300.0 0.08 -0.1113 -0.4489 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I20 compound treatment 789428.0 134000.0 0.98 670538.0 -12100.0 -0.09 0.6299 0.6382 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I21 mock treatment 682406.0 27400.0 0.2 689674.0 7040.0 0.05 0.1793 0.8657 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I22 mock treatment 644149.0 -10900.0 -0.08 638786.0 -43900.0 -0.33 -0.2919 -0.8523 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I23 compound treatment 619330.0 -35700.0 -0.26 625925.0 -56700.0 -0.43 -0.4894 -0.9713 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 I24 compound treatment 681305.0 26300.0 0.19 610764.0 -71900.0 -0.55 -0.2503 -0.4325 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J01 compound treatment 511142.0 -144000.0 -1.05 497408.0 -185000.0 -1.41 -1.7392 -0.9898 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J02 compound treatment 578535.0 -76500.0 -0.56 584447.0 -98200.0 -0.75 -0.9231 -0.99 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J03 compound treatment 732568.0 77500.0 0.57 735308.0 52700.0 0.4 0.6838 0.9855 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J04 compound treatment 691554.0 36500.0 0.27 729928.0 47300.0 0.36 0.4428 0.9893 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J05 mock treatment 586732.0 -68300.0 -0.5 755835.0 73200.0 0.56 0.0399 0.0534 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J06 mock treatment 519857.0 -135000.0 -0.99 694145.0 11500.0 0.09 -0.6373 -0.6421 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J07 compound treatment 517410.0 -138000.0 -1.01 564871.0 -118000.0 -0.89 -1.3444 -0.9983 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J08 compound treatment 572202.0 -82800.0 -0.61 620745.0 -61900.0 -0.47 -0.7609 -0.9921 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J09 compound treatment 509782.0 -145000.0 -1.06 546688.0 -136000.0 -1.03 -1.4815 -0.9999 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J10 compound treatment 596359.0 -58700.0 -0.43 709471.0 26800.0 0.2 -0.1594 -0.3354 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J11 compound treatment 483107.0 -172000.0 -1.26 507819.0 -175000.0 -1.33 -1.8282 -0.9996 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J12 compound treatment 613070.0 -42000.0 -0.31 579491.0 -103000.0 -0.78 -0.7712 -0.9163 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J13 compound treatment 205323.0 -450000.0 -3.29 218391.0 -464000.0 -3.53 -4.8194 -0.9994 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J14 compound treatment 324309.0 -331000.0 -2.42 360696.0 -322000.0 -2.45 -3.4397 -1.0 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J15 compound treatment 634349.0 -20700.0 -0.15 787199.0 105000.0 0.79 0.4546 0.5622 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J16 compound treatment 713595.0 58500.0 0.43 874385.0 192000.0 1.46 1.3328 0.8778 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J17 compound treatment 672569.0 17500.0 0.13 693826.0 11200.0 0.09 0.1507 0.9801 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J18 compound treatment 396162.0 -259000.0 -1.89 414601.0 -268000.0 -2.04 -2.7786 -0.9993 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J19 compound treatment 712152.0 57100.0 0.42 691838.0 9200.0 0.07 0.3447 0.8141 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J20 compound treatment 373585.0 -281000.0 -2.06 363669.0 -319000.0 -2.42 -3.1689 -0.9967 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J21 mock treatment 683251.0 28200.0 0.21 719797.0 37200.0 0.28 0.3454 0.9881 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J22 mock treatment 721285.0 66200.0 0.48 648045.0 -34600.0 -0.26 0.1567 0.2843 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J23 compound treatment 739289.0 84200.0 0.62 823590.0 141000.0 1.07 1.1928 0.9655 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 J24 compound treatment 586806.0 -68200.0 -0.5 590486.0 -92200.0 -0.7 -0.8479 -0.9862 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K01 compound treatment 631617.0 -23400.0 -0.17 688384.0 5750.0 0.04 -0.0903 -0.5106 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K02 compound treatment 566169.0 -88900.0 -0.65 636418.0 -46200.0 -0.35 -0.7079 -0.9582 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K03 compound treatment 718706.0 63700.0 0.47 778760.0 96100.0 0.73 0.8455 0.9764 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K04 compound treatment 757457.0 102000.0 0.75 816278.0 134000.0 1.02 1.2474 0.9888 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K05 compound treatment 356357.0 -299000.0 -2.18 503078.0 -180000.0 -1.36 -2.5091 -0.9743 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K06 compound treatment 534805.0 -120000.0 -0.88 579269.0 -103000.0 -0.79 -1.1771 -0.9984 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K07 mock treatment 595426.0 -59600.0 -0.44 740964.0 58300.0 0.44 0.005 0.008 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K08 mock treatment 646805.0 -8250.0 -0.06 674244.0 -8390.0 -0.06 -0.0877 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K09 compound treatment 651750.0 -3300.0 -0.02 747438.0 64800.0 0.49 0.331 0.6716 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K10 compound treatment 660847.0 5800.0 0.04 732686.0 50000.0 0.38 0.2988 0.7811 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K11 compound treatment 535747.0 -119000.0 -0.87 589013.0 -93600.0 -0.71 -1.1199 -0.9949 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K12 compound treatment 712060.0 57000.0 0.42 734111.0 51500.0 0.39 0.5713 0.9995 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K13 compound treatment 604107.0 -50900.0 -0.37 796762.0 114000.0 0.87 0.3496 0.3705 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K14 compound treatment 740096.0 85000.0 0.62 867401.0 185000.0 1.4 1.4323 0.9329 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K15 mock treatment 587201.0 -67800.0 -0.5 682040.0 -597.0 0.0 -0.3541 -0.7135 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K16 mock treatment 670733.0 15700.0 0.11 699939.0 17300.0 0.13 0.174 0.9977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K17 compound treatment 611127.0 -43900.0 -0.32 697349.0 14700.0 0.11 -0.1481 -0.4355 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K18 compound treatment 770251.0 115000.0 0.84 783960.0 101000.0 0.77 1.14 0.999 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K19 compound treatment 159251.0 -496000.0 -3.63 133690.0 -549000.0 -4.17 -5.5127 -0.9976 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K20 compound treatment 548827.0 -106000.0 -0.78 485234.0 -197000.0 -1.5 -1.6097 -0.9531 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K21 compound treatment 697933.0 42900.0 0.31 722781.0 40100.0 0.3 0.4374 0.9999 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K22 compound treatment 551499.0 -104000.0 -0.76 556185.0 -126000.0 -0.96 -1.2147 -0.9931 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K23 mock treatment 640507.0 -14500.0 -0.11 646560.0 -36100.0 -0.27 -0.269 -0.915 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 K24 mock treatment 620888.0 -34200.0 -0.25 605404.0 -77200.0 -0.59 -0.5915 -0.9276 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L01 compound treatment 748667.0 93600.0 0.68 787893.0 105000.0 0.8 1.0495 0.997 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L02 compound treatment 594737.0 -60300.0 -0.44 586323.0 -96300.0 -0.73 -0.8293 -0.9706 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L03 compound treatment 707621.0 52600.0 0.38 785034.0 102000.0 0.78 0.8219 0.9472 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L04 compound treatment 762538.0 107000.0 0.79 731731.0 49100.0 0.37 0.8196 0.942 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L05 compound treatment 673364.0 18300.0 0.13 703518.0 20900.0 0.16 0.2069 0.9965 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L06 compound treatment 582180.0 -72900.0 -0.53 692111.0 9470.0 0.07 -0.3259 -0.6061 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L07 mock treatment 735937.0 80900.0 0.59 706178.0 23500.0 0.18 0.5447 0.8815 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L08 mock treatment 664866.0 9820.0 0.07 649701.0 -32900.0 -0.25 -0.1262 -0.4847 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L09 compound treatment 571946.0 -83100.0 -0.61 579878.0 -103000.0 -0.78 -0.9817 -0.9923 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L10 compound treatment 639939.0 -15100.0 -0.11 709626.0 27000.0 0.21 0.0668 0.2869 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L11 compound treatment 561049.0 -94000.0 -0.69 595046.0 -87600.0 -0.67 -0.9566 -0.9999 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L12 compound treatment 620696.0 -34400.0 -0.25 719920.0 37300.0 0.28 0.0226 0.0597 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L13 compound treatment 392069.0 -263000.0 -1.92 277305.0 -405000.0 -3.08 -3.5373 -0.9743 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L14 compound treatment 548332.0 -107000.0 -0.78 561368.0 -121000.0 -0.92 -1.2033 -0.9966 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L15 mock treatment 688543.0 33500.0 0.24 752988.0 70400.0 0.53 0.5511 0.9374 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L16 mock treatment 633683.0 -21400.0 -0.16 696213.0 13600.0 0.1 -0.0376 -0.2007 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L17 compound treatment 654964.0 -86.9 0.0 709279.0 26600.0 0.2 0.1427 0.7049 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L18 compound treatment 412750.0 -242000.0 -1.77 461609.0 -221000.0 -1.68 -2.4403 -0.9996 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L19 compound treatment 712270.0 57200.0 0.42 734459.0 51800.0 0.39 0.5743 0.9995 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L20 compound treatment 654596.0 -455.0 0.0 613662.0 -69000.0 -0.52 -0.3729 -0.7116 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L21 compound treatment 663286.0 8240.0 0.06 725684.0 43000.0 0.33 0.2738 0.8235 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L22 compound treatment 741561.0 86500.0 0.63 737069.0 54400.0 0.41 0.7398 0.9788 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L23 mock treatment 649849.0 -5200.0 -0.04 708433.0 25800.0 0.2 0.1117 0.5594 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 L24 mock treatment 619577.0 -35500.0 -0.26 670809.0 -11800.0 -0.09 -0.247 -0.8996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M01 compound treatment 651275.0 -3780.0 -0.03 661695.0 -20900.0 -0.16 -0.132 -0.8176 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M02 compound treatment 656535.0 1480.0 0.01 643410.0 -39200.0 -0.3 -0.203 -0.6809 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M03 compound treatment 547642.0 -107000.0 -0.79 742332.0 59700.0 0.45 -0.2348 -0.2588 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M04 compound treatment 572050.0 -83000.0 -0.61 794021.0 111000.0 0.85 0.1691 0.1624 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M05 compound treatment 657842.0 2790.0 0.02 771721.0 89100.0 0.68 0.493 0.7281 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M06 compound treatment 737885.0 82800.0 0.61 754521.0 71900.0 0.55 0.8145 0.9987 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M07 compound treatment 663416.0 8370.0 0.06 859072.0 176000.0 1.34 0.991 0.7386 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M08 compound treatment 737733.0 82700.0 0.6 688800.0 6160.0 0.05 0.4607 0.7596 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M09 mock treatment 724871.0 69800.0 0.51 738877.0 56200.0 0.43 0.6632 0.9961 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M10 mock treatment 843720.0 189000.0 1.38 784002.0 101000.0 0.77 1.5201 0.9621 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M11 compound treatment 648815.0 -6240.0 -0.05 733876.0 51200.0 0.39 0.243 0.62 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M12 compound treatment 592012.0 -63000.0 -0.46 636126.0 -46500.0 -0.35 -0.5758 -0.9914 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M13 mock treatment 667597.0 12500.0 0.09 610321.0 -72300.0 -0.55 -0.3236 -0.581 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M14 mock treatment 822496.0 167000.0 1.22 639614.0 -43000.0 -0.33 0.6348 0.5008 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M15 compound treatment 771713.0 117000.0 0.85 807986.0 125000.0 0.95 1.2766 0.9985 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M16 compound treatment 856978.0 202000.0 1.48 845476.0 163000.0 1.24 1.9189 0.9961 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M17 compound treatment 696536.0 41500.0 0.3 839104.0 156000.0 1.19 1.055 0.86 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M18 compound treatment 804266.0 149000.0 1.09 787011.0 104000.0 0.79 1.3323 0.9877 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M19 compound treatment 744818.0 89800.0 0.66 757251.0 74600.0 0.57 0.865 0.9973 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M20 compound treatment 759009.0 104000.0 0.76 816284.0 134000.0 1.02 1.2555 0.9898 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M21 compound treatment 671691.0 16600.0 0.12 683084.0 447.0 0.0 0.0885 0.7266 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M22 compound treatment 820309.0 165000.0 1.21 827174.0 145000.0 1.1 1.631 0.9989 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M23 compound treatment 124426.0 -531000.0 -3.88 130225.0 -552000.0 -4.2 -5.7114 -0.9992 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 M24 compound treatment 716279.0 61200.0 0.45 647891.0 -34700.0 -0.26 0.13 0.2501 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N01 compound treatment 677169.0 22100.0 0.16 682877.0 240.0 0.0 0.1157 0.715 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N02 compound treatment 737246.0 82200.0 0.6 611086.0 -71600.0 -0.54 0.0407 0.0502 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N03 compound treatment 483440.0 -172000.0 -1.26 653019.0 -29600.0 -0.22 -1.0465 -0.8208 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N04 compound treatment 606231.0 -48800.0 -0.36 788598.0 106000.0 0.8 0.3167 0.3597 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N05 compound treatment 655756.0 705.0 0.01 659367.0 -23300.0 -0.18 -0.1214 -0.6862 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N06 compound treatment 709067.0 54000.0 0.4 785830.0 103000.0 0.78 0.8337 0.9497 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N07 compound treatment 608777.0 -46300.0 -0.34 656986.0 -25700.0 -0.19 -0.3771 -0.9656 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N08 compound treatment 584473.0 -70600.0 -0.52 623411.0 -59200.0 -0.45 -0.6831 -0.9977 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N09 mock treatment 804293.0 149000.0 1.09 847294.0 165000.0 1.25 1.6562 0.9977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N10 mock treatment 659155.0 4100.0 0.03 784706.0 102000.0 0.78 0.5695 0.7339 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N11 compound treatment 784401.0 129000.0 0.95 768143.0 85500.0 0.65 1.1282 0.9832 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N12 compound treatment 783126.0 128000.0 0.94 772671.0 90000.0 0.68 1.1459 0.9881 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N13 mock treatment 668531.0 13500.0 0.1 556121.0 -127000.0 -0.96 -0.6099 -0.6313 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N14 mock treatment 668143.0 13100.0 0.1 554581.0 -128000.0 -0.97 -0.6202 -0.6344 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N15 compound treatment 813284.0 158000.0 1.16 798915.0 116000.0 0.88 1.4429 0.9911 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N16 compound treatment 769912.0 115000.0 0.84 872599.0 190000.0 1.44 1.6144 0.9668 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N17 compound treatment 569050.0 -86000.0 -0.63 464192.0 -218000.0 -1.66 -1.6182 -0.9118 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N18 compound treatment 560130.0 -94900.0 -0.69 674171.0 -8470.0 -0.06 -0.5363 -0.7693 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N19 compound treatment 792049.0 137000.0 1.0 688698.0 6060.0 0.05 0.741 0.7388 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N20 compound treatment 812772.0 158000.0 1.15 808780.0 126000.0 0.96 1.4932 0.9958 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N21 compound treatment 518769.0 -136000.0 -1.0 557338.0 -125000.0 -0.95 -1.3778 -0.9997 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N22 compound treatment 767383.0 112000.0 0.82 679448.0 -3190.0 -0.02 0.5638 0.686 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N23 compound treatment 595542.0 -59500.0 -0.44 674591.0 -8050.0 -0.06 -0.3509 -0.7986 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 N24 compound treatment 757311.0 102000.0 0.75 677388.0 -5250.0 -0.04 0.5006 0.6685 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O01 compound treatment 566713.0 -88300.0 -0.65 556934.0 -126000.0 -0.95 -1.1321 -0.9819 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O02 compound treatment 701143.0 46100.0 0.34 704823.0 22200.0 0.17 0.3575 0.9487 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O03 compound treatment 160185.0 -495000.0 -3.62 144589.0 -538000.0 -4.09 -5.4493 -0.9982 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O04 compound treatment 797977.0 143000.0 1.05 793644.0 111000.0 0.84 1.3354 0.9943 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O05 compound treatment 874226.0 219000.0 1.6 767997.0 85400.0 0.65 1.5919 0.9207 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O06 compound treatment 847177.0 192000.0 1.41 687321.0 4680.0 0.04 1.0187 0.7248 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O07 compound treatment 756916.0 102000.0 0.74 711561.0 28900.0 0.22 0.6821 0.8783 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O08 compound treatment 761427.0 106000.0 0.78 716705.0 34100.0 0.26 0.7331 0.8942 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O09 compound treatment 142861.0 -512000.0 -3.75 149243.0 -533000.0 -4.05 -5.5139 -0.9992 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O10 compound treatment 812506.0 157000.0 1.15 770321.0 87700.0 0.67 1.2852 0.9661 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O11 mock treatment 771074.0 116000.0 0.85 697668.0 15000.0 0.11 0.6807 0.7951 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O12 mock treatment 828650.0 174000.0 1.27 770087.0 87500.0 0.66 1.3675 0.9544 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O13 compound treatment 717320.0 62300.0 0.46 703648.0 21000.0 0.16 0.4349 0.9012 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O14 compound treatment 769560.0 115000.0 0.84 693837.0 11200.0 0.09 0.6523 0.775 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O15 compound treatment 735349.0 80300.0 0.59 741134.0 58500.0 0.44 0.7295 0.9906 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O16 compound treatment 708530.0 53500.0 0.39 741185.0 58500.0 0.44 0.5911 0.9979 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O17 compound treatment 428044.0 -227000.0 -1.66 517701.0 -165000.0 -1.25 -2.0599 -0.9904 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O18 compound treatment 792730.0 138000.0 1.01 717653.0 35000.0 0.27 0.9001 0.8643 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O19 compound treatment 206552.0 -448000.0 -3.28 223032.0 -460000.0 -3.49 -4.7881 -0.9995 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O20 compound treatment 734896.0 79800.0 0.58 677097.0 -5540.0 -0.04 0.3831 0.6544 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O21 compound treatment 143648.0 -511000.0 -3.74 146461.0 -536000.0 -4.07 -5.5247 -0.9991 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O22 compound treatment 728184.0 73100.0 0.53 696394.0 13800.0 0.1 0.4521 0.8296 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O23 compound treatment 680253.0 25200.0 0.18 683331.0 694.0 0.01 0.1341 0.727 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 O24 compound treatment 677247.0 22200.0 0.16 647849.0 -34800.0 -0.26 -0.0721 -0.2324 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P01 compound treatment 805483.0 150000.0 1.1 637322.0 -45300.0 -0.34 0.5345 0.4637 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P02 compound treatment 636517.0 -18500.0 -0.14 584940.0 -97700.0 -0.74 -0.6206 -0.8226 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P03 compound treatment 743211.0 88200.0 0.64 601024.0 -81600.0 -0.62 0.0175 0.0196 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P04 compound treatment 595642.0 -59400.0 -0.43 652639.0 -30000.0 -0.23 -0.4684 -0.9546 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P05 compound treatment 650443.0 -4610.0 -0.03 591215.0 -91400.0 -0.69 -0.5149 -0.7405 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P06 compound treatment 699515.0 44500.0 0.33 619113.0 -63500.0 -0.48 -0.1113 -0.1913 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P07 compound treatment 778246.0 123000.0 0.9 683332.0 695.0 0.01 0.6408 0.7112 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P08 compound treatment 902933.0 248000.0 1.81 736695.0 54100.0 0.41 1.5722 0.8459 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P09 compound treatment 802250.0 147000.0 1.08 759347.0 76700.0 0.58 1.1733 0.9585 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P10 compound treatment 769314.0 114000.0 0.84 727201.0 44600.0 0.34 0.8303 0.9209 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P11 mock treatment 818435.0 163000.0 1.19 837460.0 155000.0 1.18 1.6766 1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P12 mock treatment 711952.0 56900.0 0.42 771187.0 88600.0 0.67 0.7699 0.9733 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P13 compound treatment 772147.0 117000.0 0.86 754715.0 72100.0 0.55 0.9927 0.9767 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P14 compound treatment 752934.0 97900.0 0.72 777032.0 94400.0 0.72 1.0132 1.0 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P15 compound treatment 707820.0 52800.0 0.39 725620.0 43000.0 0.33 0.5038 0.9965 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P16 compound treatment 854230.0 199000.0 1.46 750813.0 68200.0 0.52 1.3962 0.9031 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P17 compound treatment 698658.0 43600.0 0.32 620635.0 -62000.0 -0.47 -0.1076 -0.1891 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P18 compound treatment 734462.0 79400.0 0.58 728037.0 45400.0 0.34 0.6545 0.969 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P19 compound treatment 645774.0 -9280.0 -0.07 565801.0 -117000.0 -0.89 -0.6756 -0.7589 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P20 compound treatment 762542.0 107000.0 0.79 872969.0 190000.0 1.45 1.5783 0.959 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P21 compound treatment 555644.0 -99400.0 -0.73 534348.0 -148000.0 -1.13 -1.3106 -0.9775 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P22 compound treatment 783191.0 128000.0 0.94 797612.0 115000.0 0.87 1.2802 0.9994 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P23 compound treatment 800893.0 146000.0 1.07 916393.0 234000.0 1.78 2.0098 0.9703 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2093 P24 compound treatment 527565.0 -127000.0 -0.93 636519.0 -46100.0 -0.35 -0.907 -0.9106 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A01 compound treatment 685814.0 63200.0 0.46 627985.0 5340.0 0.04 0.3557 0.7662 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A02 compound treatment 496417.0 -126000.0 -0.92 470117.0 -153000.0 -1.16 -1.4717 -0.9936 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A03 compound treatment 607283.0 -15300.0 -0.11 459478.0 -163000.0 -1.24 -0.9556 -0.7678 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A04 compound treatment 615697.0 -6880.0 -0.05 549191.0 -73500.0 -0.56 -0.4302 -0.7678 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A05 compound treatment 411073.0 -212000.0 -1.55 465859.0 -157000.0 -1.19 -1.9359 -0.9917 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A06 compound treatment 495287.0 -127000.0 -0.93 437597.0 -185000.0 -1.41 -1.6523 -0.98 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A07 compound treatment 569414.0 -53200.0 -0.39 594592.0 -28100.0 -0.21 -0.4256 -0.96 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A08 compound treatment 474921.0 -148000.0 -1.08 422376.0 -200000.0 -1.52 -1.8394 -0.9859 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A09 compound treatment 599229.0 -23300.0 -0.17 548826.0 -73800.0 -0.56 -0.5173 -0.8824 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A10 compound treatment 571596.0 -51000.0 -0.37 476567.0 -146000.0 -1.11 -1.0483 -0.8955 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A11 compound treatment 558247.0 -64300.0 -0.47 529996.0 -92700.0 -0.7 -0.8304 -0.9808 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A12 compound treatment 588508.0 -34100.0 -0.25 532065.0 -90600.0 -0.69 -0.6628 -0.9056 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A13 mock treatment 634727.0 12100.0 0.09 625264.0 2620.0 0.02 0.0769 0.8444 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A14 mock treatment 716806.0 94200.0 0.69 673440.0 50800.0 0.39 0.7601 0.9624 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A15 compound treatment 622187.0 -390.0 0.0 680606.0 58000.0 0.44 0.3093 0.7025 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A16 compound treatment 529123.0 -93500.0 -0.68 549524.0 -73100.0 -0.56 -0.8761 -0.9947 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A17 compound treatment 571474.0 -51100.0 -0.37 629205.0 6560.0 0.05 -0.229 -0.6075 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A18 compound treatment 412194.0 -210000.0 -1.54 445903.0 -177000.0 -1.34 -2.0373 -0.9977 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A19 compound treatment 447094.0 -175000.0 -1.28 474747.0 -148000.0 -1.12 -1.7019 -0.9978 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A20 compound treatment 549332.0 -73200.0 -0.54 557824.0 -64800.0 -0.49 -0.727 -0.9991 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A21 compound treatment 489765.0 -133000.0 -0.97 567176.0 -55500.0 -0.42 -0.9848 -0.9301 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A22 compound treatment 598239.0 -24300.0 -0.18 671206.0 48600.0 0.37 0.135 0.3296 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A23 compound treatment 578808.0 -43800.0 -0.32 590554.0 -32100.0 -0.24 -0.3987 -0.991 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 A24 compound treatment 601320.0 -21300.0 -0.16 637516.0 14900.0 0.11 -0.0301 -0.1564 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B01 compound treatment 563008.0 -59600.0 -0.44 530844.0 -91800.0 -0.7 -0.8012 -0.9743 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B02 compound treatment 452740.0 -170000.0 -1.24 429087.0 -194000.0 -1.47 -1.918 -0.9965 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B03 compound treatment 505535.0 -117000.0 -0.86 463528.0 -159000.0 -1.21 -1.46 -0.9857 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B04 compound treatment 250266.0 -372000.0 -2.72 228366.0 -394000.0 -3.0 -4.0433 -0.9989 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B05 compound treatment 593721.0 -28900.0 -0.21 531233.0 -91400.0 -0.69 -0.6403 -0.8822 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B06 compound treatment 366499.0 -256000.0 -1.87 322733.0 -300000.0 -2.28 -2.9353 -0.9953 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B07 compound treatment 460882.0 -162000.0 -1.18 465165.0 -157000.0 -1.2 -1.6821 -1.0 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B08 compound treatment 502358.0 -120000.0 -0.88 520838.0 -102000.0 -0.77 -1.1686 -0.998 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B09 compound treatment 631119.0 8540.0 0.06 504132.0 -119000.0 -0.9 -0.5925 -0.6565 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B10 compound treatment 446823.0 -176000.0 -1.29 319092.0 -304000.0 -2.31 -2.5395 -0.9619 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B11 compound treatment 385016.0 -238000.0 -1.74 520404.0 -102000.0 -0.78 -1.7777 -0.9341 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B12 compound treatment 136866.0 -486000.0 -3.55 122864.0 -500000.0 -3.8 -5.1964 -0.9994 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B13 mock treatment 573858.0 -48700.0 -0.36 637570.0 14900.0 0.11 -0.1718 -0.4594 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B14 mock treatment 573711.0 -48900.0 -0.36 605132.0 -17500.0 -0.13 -0.3468 -0.9094 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B15 compound treatment 590615.0 -32000.0 -0.23 631677.0 9030.0 0.07 -0.1168 -0.4794 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B16 compound treatment 428861.0 -194000.0 -1.42 455734.0 -167000.0 -1.27 -1.8983 -0.9985 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B17 compound treatment 679012.0 56400.0 0.41 645893.0 23200.0 0.18 0.4167 0.9283 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B18 compound treatment 431130.0 -191000.0 -1.4 303742.0 -319000.0 -2.42 -2.7031 -0.966 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B19 compound treatment 447522.0 -175000.0 -1.28 422161.0 -200000.0 -1.52 -1.9822 -0.9963 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B20 compound treatment 453588.0 -169000.0 -1.24 462145.0 -161000.0 -1.22 -1.736 -1.0 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B21 compound treatment 401857.0 -221000.0 -1.61 482378.0 -140000.0 -1.07 -1.8949 -0.9797 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B22 compound treatment 303315.0 -319000.0 -2.33 302738.0 -320000.0 -2.43 -3.3694 -0.9998 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B23 compound treatment 432250.0 -190000.0 -1.39 448064.0 -175000.0 -1.33 -1.922 -0.9997 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 B24 compound treatment 529365.0 -93200.0 -0.68 475445.0 -147000.0 -1.12 -1.2727 -0.9718 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C01 compound treatment 576725.0 -45900.0 -0.34 612034.0 -10600.0 -0.08 -0.2941 -0.8528 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C02 compound treatment 586731.0 -35800.0 -0.26 585260.0 -37400.0 -0.28 -0.3862 -0.9992 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C03 compound treatment 563352.0 -59200.0 -0.43 587959.0 -34700.0 -0.26 -0.4926 -0.9716 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C04 compound treatment 577860.0 -44700.0 -0.33 514232.0 -108000.0 -0.82 -0.8136 -0.9181 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C05 compound treatment 645323.0 22700.0 0.17 524065.0 -98600.0 -0.75 -0.4119 -0.537 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C06 compound treatment 605364.0 -17200.0 -0.13 578018.0 -44600.0 -0.34 -0.3287 -0.909 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C07 compound treatment 691824.0 69200.0 0.51 594983.0 -27700.0 -0.21 0.2095 0.3821 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C08 compound treatment 584259.0 -38300.0 -0.28 581242.0 -41400.0 -0.31 -0.4206 -0.9983 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C09 compound treatment 686119.0 63500.0 0.46 572953.0 -49700.0 -0.38 0.0616 0.103 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C10 compound treatment 451112.0 -171000.0 -1.25 408326.0 -214000.0 -1.63 -2.0379 -0.9917 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C11 mock treatment 602285.0 -20300.0 -0.15 580234.0 -42400.0 -0.32 -0.3328 -0.9381 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C12 mock treatment 585941.0 -36600.0 -0.27 547153.0 -75500.0 -0.57 -0.595 -0.9399 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C13 compound treatment 640955.0 18400.0 0.13 624589.0 1940.0 0.01 0.1055 0.78 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C14 compound treatment 662166.0 39600.0 0.29 625511.0 2860.0 0.02 0.2201 0.7581 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C15 mock treatment 638832.0 16300.0 0.12 217952.0 -405000.0 -3.07 -2.0899 -0.6793 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C16 mock treatment 598905.0 -23700.0 -0.17 594376.0 -28300.0 -0.21 -0.2743 -0.9943 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C17 compound treatment 590966.0 -31600.0 -0.23 519562.0 -103000.0 -0.78 -0.7172 -0.8784 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C18 compound treatment 673786.0 51200.0 0.37 676943.0 54300.0 0.41 0.5565 0.9988 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C19 compound treatment 631177.0 8600.0 0.06 611346.0 -11300.0 -0.09 -0.0162 -0.1526 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C20 compound treatment 400853.0 -222000.0 -1.62 503983.0 -119000.0 -0.9 -1.784 -0.9616 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C21 compound treatment 643521.0 20900.0 0.15 660873.0 38200.0 0.29 0.3136 0.9553 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C22 compound treatment 632343.0 9770.0 0.07 628953.0 6310.0 0.05 0.0844 0.9811 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C23 compound treatment 671041.0 48500.0 0.35 653597.0 30900.0 0.24 0.4169 0.9801 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 C24 compound treatment 651316.0 28700.0 0.21 597462.0 -25200.0 -0.19 0.0133 0.0469 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D01 compound treatment 579631.0 -42900.0 -0.31 549739.0 -72900.0 -0.55 -0.6137 -0.9639 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D02 compound treatment 461625.0 -161000.0 -1.18 469050.0 -154000.0 -1.17 -1.6574 -1.0 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D03 compound treatment 451428.0 -171000.0 -1.25 398503.0 -224000.0 -1.7 -2.0891 -0.9885 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D04 compound treatment 454912.0 -168000.0 -1.23 437149.0 -185000.0 -1.41 -1.8635 -0.9976 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D05 compound treatment 529727.0 -92900.0 -0.68 394947.0 -228000.0 -1.73 -1.7033 -0.9166 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D06 compound treatment 495638.0 -127000.0 -0.93 434832.0 -188000.0 -1.43 -1.6653 -0.9783 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D07 compound treatment 522372.0 -100000.0 -0.73 441523.0 -181000.0 -1.38 -1.4911 -0.9565 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D08 compound treatment 550026.0 -72600.0 -0.53 488981.0 -134000.0 -1.02 -1.0932 -0.9542 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D09 compound treatment 630376.0 7800.0 0.06 530661.0 -92000.0 -0.7 -0.4538 -0.6472 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D10 compound treatment 417962.0 -205000.0 -1.5 391569.0 -231000.0 -1.76 -2.2994 -0.9968 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D11 mock treatment 561906.0 -60700.0 -0.44 449624.0 -173000.0 -1.31 -1.2432 -0.8961 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D12 mock treatment 625974.0 3400.0 0.02 581571.0 -41100.0 -0.31 -0.2031 -0.6488 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D13 compound treatment 527329.0 -95200.0 -0.7 566363.0 -56300.0 -0.43 -0.7949 -0.9725 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D14 compound treatment 451278.0 -171000.0 -1.25 549039.0 -73600.0 -0.56 -1.2812 -0.9339 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D15 mock treatment 463729.0 -159000.0 -1.16 637231.0 14600.0 0.11 -0.7431 -0.6368 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D16 mock treatment 676388.0 53800.0 0.39 655790.0 33100.0 0.25 0.4563 0.9767 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D17 compound treatment 422890.0 -200000.0 -1.46 468816.0 -154000.0 -1.17 -1.859 -0.9939 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D18 compound treatment 512722.0 -110000.0 -0.8 526155.0 -96500.0 -0.73 -1.0864 -0.999 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D19 compound treatment 647299.0 24700.0 0.18 522788.0 -99900.0 -0.76 -0.4086 -0.5239 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D20 compound treatment 620897.0 -1680.0 -0.01 527207.0 -95400.0 -0.73 -0.5214 -0.719 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D21 compound treatment 478315.0 -144000.0 -1.06 486762.0 -136000.0 -1.03 -1.4759 -0.9999 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D22 compound treatment 565153.0 -57400.0 -0.42 697619.0 75000.0 0.57 0.1058 0.1495 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D23 compound treatment 610677.0 -11900.0 -0.09 599464.0 -23200.0 -0.18 -0.1861 -0.9472 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 D24 compound treatment 151217.0 -471000.0 -3.45 156085.0 -467000.0 -3.54 -4.9437 -0.9999 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E01 mock treatment 512755.0 -110000.0 -0.8 554505.0 -68100.0 -0.52 -0.9339 -0.9774 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E02 mock treatment 543379.0 -79200.0 -0.58 573729.0 -48900.0 -0.37 -0.6723 -0.977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E03 compound treatment 673316.0 50700.0 0.37 635742.0 13100.0 0.1 0.3327 0.8661 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E04 compound treatment 586170.0 -36400.0 -0.27 509174.0 -113000.0 -0.86 -0.7978 -0.8843 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E05 compound treatment 529292.0 -93300.0 -0.68 588569.0 -34100.0 -0.26 -0.6655 -0.912 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E06 compound treatment 593636.0 -28900.0 -0.21 621977.0 -670.0 -0.01 -0.1533 -0.7239 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E07 compound treatment 439229.0 -183000.0 -1.34 560008.0 -62600.0 -0.48 -1.2846 -0.9029 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E08 compound treatment 691788.0 69200.0 0.51 658350.0 35700.0 0.27 0.5497 0.9572 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E09 mock treatment 658738.0 36200.0 0.26 539699.0 -82900.0 -0.63 -0.2586 -0.3784 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E10 mock treatment 597115.0 -25500.0 -0.19 552477.0 -70200.0 -0.53 -0.5086 -0.9007 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E11 compound treatment 551797.0 -70800.0 -0.52 514748.0 -108000.0 -0.82 -0.9456 -0.9754 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E12 compound treatment 588687.0 -33900.0 -0.25 595079.0 -27600.0 -0.21 -0.3233 -0.9965 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E13 compound treatment 588088.0 -34500.0 -0.25 607669.0 -15000.0 -0.11 -0.2588 -0.9353 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E14 compound treatment 635861.0 13300.0 0.1 593911.0 -28700.0 -0.22 -0.0857 -0.3585 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E15 compound treatment 608039.0 -14500.0 -0.11 589582.0 -33100.0 -0.25 -0.2528 -0.9268 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E16 compound treatment 618905.0 -3670.0 -0.03 562882.0 -59800.0 -0.45 -0.34 -0.7476 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E17 mock treatment 618060.0 -4520.0 -0.03 640893.0 18200.0 0.14 0.0747 0.5239 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E18 mock treatment 593492.0 -29100.0 -0.21 609873.0 -12800.0 -0.1 -0.219 -0.9368 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E19 compound treatment 622102.0 -475.0 0.0 699258.0 76600.0 0.58 0.4091 0.7029 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E20 compound treatment 390815.0 -232000.0 -1.69 505458.0 -117000.0 -0.89 -1.828 -0.9548 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E21 compound treatment 478479.0 -144000.0 -1.05 504245.0 -118000.0 -0.9 -1.3812 -0.9969 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E22 compound treatment 534650.0 -87900.0 -0.64 642178.0 19500.0 0.15 -0.3498 -0.53 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E23 compound treatment 541498.0 -81100.0 -0.59 598240.0 -24400.0 -0.19 -0.5504 -0.8859 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 E24 compound treatment 629810.0 7230.0 0.05 593119.0 -29500.0 -0.22 -0.1212 -0.526 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F01 mock treatment 597806.0 -24800.0 -0.18 537193.0 -85500.0 -0.65 -0.5871 -0.8711 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F02 mock treatment 545987.0 -76600.0 -0.56 578412.0 -44200.0 -0.34 -0.6337 -0.9701 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F03 compound treatment 602774.0 -19800.0 -0.14 541218.0 -81400.0 -0.62 -0.5398 -0.8497 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F04 compound treatment 212719.0 -410000.0 -3.0 154024.0 -469000.0 -3.56 -4.6368 -0.9963 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F05 compound treatment 504050.0 -119000.0 -0.87 488649.0 -134000.0 -1.02 -1.3327 -0.9968 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F06 compound treatment 204163.0 -418000.0 -3.06 139442.0 -483000.0 -3.67 -4.7593 -0.9959 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F07 compound treatment 373294.0 -249000.0 -1.82 366080.0 -257000.0 -1.95 -2.6673 -0.9994 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F08 compound treatment 334040.0 -289000.0 -2.11 308131.0 -315000.0 -2.39 -3.1816 -0.9981 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F09 mock treatment 506635.0 -116000.0 -0.85 502631.0 -120000.0 -0.91 -1.2443 -0.9993 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F10 mock treatment 650908.0 28300.0 0.21 497731.0 -125000.0 -0.95 -0.5245 -0.54 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F11 compound treatment 538552.0 -84000.0 -0.61 492956.0 -130000.0 -0.99 -1.1312 -0.9742 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F12 compound treatment 400493.0 -222000.0 -1.62 478859.0 -144000.0 -1.09 -1.9208 -0.9814 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F13 compound treatment 488830.0 -134000.0 -0.98 511654.0 -111000.0 -0.84 -1.2879 -0.9973 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F14 compound treatment 121941.0 -501000.0 -3.66 125451.0 -497000.0 -3.78 -5.2597 -0.9999 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F15 compound treatment 391106.0 -231000.0 -1.69 391597.0 -231000.0 -1.76 -2.4381 -0.9998 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F16 compound treatment 333303.0 -289000.0 -2.12 248378.0 -374000.0 -2.84 -3.5064 -0.9894 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F17 mock treatment 589956.0 -32600.0 -0.24 633451.0 10800.0 0.08 -0.1107 -0.4386 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F18 mock treatment 525964.0 -96600.0 -0.71 540699.0 -81900.0 -0.62 -0.9398 -0.998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F19 compound treatment 453990.0 -169000.0 -1.23 499809.0 -123000.0 -0.93 -1.5316 -0.9906 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F20 compound treatment 245588.0 -377000.0 -2.76 294295.0 -328000.0 -2.49 -3.7133 -0.9988 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F21 compound treatment 622618.0 40.5 0.0 683123.0 60500.0 0.46 0.3251 0.7076 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F22 compound treatment 483255.0 -139000.0 -1.02 512882.0 -110000.0 -0.83 -1.3101 -0.9951 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F23 compound treatment 433240.0 -189000.0 -1.38 533937.0 -88700.0 -0.67 -1.4556 -0.9452 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 F24 compound treatment 193023.0 -430000.0 -3.14 204417.0 -418000.0 -3.18 -4.4679 -1.0 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G01 compound treatment 579029.0 -43500.0 -0.32 552369.0 -70300.0 -0.53 -0.6027 -0.9695 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G02 compound treatment 563159.0 -59400.0 -0.43 560416.0 -62200.0 -0.47 -0.6416 -0.9991 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G03 mock treatment 540096.0 -82500.0 -0.6 618831.0 -3820.0 -0.03 -0.447 -0.7402 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G04 mock treatment 604778.0 -17800.0 -0.13 538852.0 -83800.0 -0.64 -0.5422 -0.8344 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G05 compound treatment 621335.0 -1240.0 -0.01 630460.0 7810.0 0.06 0.0355 0.592 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G06 compound treatment 582224.0 -40400.0 -0.3 613939.0 -8710.0 -0.07 -0.2555 -0.8447 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G07 compound treatment 603005.0 -19600.0 -0.14 541072.0 -81600.0 -0.62 -0.5394 -0.8481 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G08 compound treatment 691750.0 69200.0 0.51 657927.0 35300.0 0.27 0.5472 0.9559 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G09 compound treatment 581665.0 -40900.0 -0.3 491174.0 -131000.0 -1.0 -0.9178 -0.8803 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G10 compound treatment 527670.0 -94900.0 -0.69 562352.0 -60300.0 -0.46 -0.8147 -0.9797 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G11 compound treatment 708710.0 86100.0 0.63 672948.0 50300.0 0.38 0.7156 0.9713 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G12 compound treatment 549015.0 -73600.0 -0.54 575314.0 -47300.0 -0.36 -0.6347 -0.9808 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G13 compound treatment 596761.0 -25800.0 -0.19 568802.0 -53800.0 -0.41 -0.4227 -0.9383 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G14 compound treatment 543254.0 -79300.0 -0.58 554271.0 -68400.0 -0.52 -0.7775 -0.9985 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G15 compound treatment 596906.0 -25700.0 -0.19 664321.0 41700.0 0.32 0.0911 0.2475 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G16 compound treatment 583581.0 -39000.0 -0.29 626321.0 3670.0 0.03 -0.1819 -0.6349 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G17 compound treatment 678626.0 56000.0 0.41 556485.0 -66200.0 -0.5 -0.0656 -0.1011 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G18 compound treatment 558081.0 -64500.0 -0.47 553515.0 -69100.0 -0.53 -0.7049 -0.9986 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G19 mock treatment 654661.0 32100.0 0.23 682662.0 60000.0 0.46 0.4883 0.9523 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G20 mock treatment 602425.0 -20200.0 -0.15 637828.0 15200.0 0.12 -0.0227 -0.1211 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G21 compound treatment 550908.0 -71700.0 -0.52 612299.0 -10300.0 -0.08 -0.4262 -0.8042 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G22 compound treatment 702582.0 80000.0 0.59 727450.0 105000.0 0.8 0.9767 0.9885 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G23 compound treatment 697752.0 75200.0 0.55 770493.0 148000.0 1.12 1.1829 0.946 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 G24 compound treatment 556358.0 -66200.0 -0.48 622066.0 -581.0 0.0 -0.3456 -0.7135 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H01 compound treatment 545341.0 -77200.0 -0.56 461901.0 -161000.0 -1.22 -1.2629 -0.9386 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H02 compound treatment 466955.0 -156000.0 -1.14 460169.0 -162000.0 -1.23 -1.6775 -0.9992 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H03 mock treatment 614752.0 -7830.0 -0.06 585289.0 -37400.0 -0.28 -0.2411 -0.8329 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H04 mock treatment 559533.0 -63000.0 -0.46 537093.0 -85600.0 -0.65 -0.7856 -0.9859 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H05 compound treatment 514609.0 -108000.0 -0.79 511014.0 -112000.0 -0.85 -1.158 -0.9994 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H06 compound treatment 149634.0 -473000.0 -3.46 121628.0 -501000.0 -3.81 -5.137 -0.9989 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H07 compound treatment 497944.0 -125000.0 -0.91 441997.0 -181000.0 -1.37 -1.6149 -0.9802 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H08 compound treatment 418891.0 -204000.0 -1.49 432121.0 -191000.0 -1.45 -2.0767 -0.9999 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H09 compound treatment 487917.0 -135000.0 -0.98 580914.0 -41700.0 -0.32 -0.9205 -0.8898 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H10 compound treatment 516728.0 -106000.0 -0.77 484052.0 -139000.0 -1.05 -1.2919 -0.9886 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H11 compound treatment 563112.0 -59500.0 -0.43 536780.0 -85900.0 -0.65 -0.7688 -0.9806 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H12 compound treatment 409904.0 -213000.0 -1.56 473590.0 -149000.0 -1.13 -1.9005 -0.9878 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H13 compound treatment 519562.0 -103000.0 -0.75 452930.0 -170000.0 -1.29 -1.4444 -0.9673 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H14 compound treatment 498086.0 -124000.0 -0.91 504468.0 -118000.0 -0.9 -1.2786 -1.0 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H15 compound treatment 590174.0 -32400.0 -0.24 595248.0 -27400.0 -0.21 -0.3147 -0.9979 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H16 compound treatment 515159.0 -107000.0 -0.79 521245.0 -101000.0 -0.77 -1.1002 -1.0 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H17 compound treatment 680924.0 58300.0 0.43 717227.0 94600.0 0.72 0.8098 0.969 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H18 compound treatment 467613.0 -155000.0 -1.13 535511.0 -87100.0 -0.66 -1.2694 -0.9672 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H19 mock treatment 663215.0 40600.0 0.3 578809.0 -43800.0 -0.33 -0.0253 -0.0568 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H20 mock treatment 690346.0 67800.0 0.5 621376.0 -1270.0 -0.01 0.3436 0.6932 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H21 compound treatment 605043.0 -17500.0 -0.13 808777.0 186000.0 1.41 0.9092 0.6404 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H22 compound treatment 314272.0 -308000.0 -2.25 321917.0 -301000.0 -2.28 -3.2097 -1.0 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H23 compound treatment 523114.0 -99500.0 -0.73 553031.0 -69600.0 -0.53 -0.8883 -0.9877 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 H24 compound treatment 623537.0 960.0 0.01 653381.0 30700.0 0.23 0.1701 0.728 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I01 compound treatment 696757.0 74200.0 0.54 657180.0 34500.0 0.26 0.5691 0.9444 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I02 compound treatment 521011.0 -102000.0 -0.74 514994.0 -108000.0 -0.82 -1.1035 -0.9988 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I03 compound treatment 531169.0 -91400.0 -0.67 677097.0 54400.0 0.41 -0.1802 -0.2292 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I04 compound treatment 420610.0 -202000.0 -1.48 449068.0 -174000.0 -1.32 -1.9768 -0.9984 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I05 mock treatment 554033.0 -68500.0 -0.5 654908.0 32300.0 0.25 -0.1812 -0.3247 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I06 mock treatment 649430.0 26900.0 0.2 581653.0 -41000.0 -0.31 -0.0814 -0.221 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I07 compound treatment 712509.0 89900.0 0.66 739617.0 117000.0 0.89 1.0934 0.989 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I08 compound treatment 570444.0 -52100.0 -0.38 620144.0 -2500.0 -0.02 -0.283 -0.7415 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I09 compound treatment 517223.0 -105000.0 -0.77 575733.0 -46900.0 -0.36 -0.7968 -0.9386 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I10 compound treatment 498230.0 -124000.0 -0.91 510062.0 -113000.0 -0.86 -1.2478 -0.9995 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I11 compound treatment 694158.0 71600.0 0.52 680880.0 58200.0 0.44 0.683 0.9965 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I12 compound treatment 410294.0 -212000.0 -1.55 510374.0 -112000.0 -0.85 -1.7009 -0.9602 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I13 compound treatment 597940.0 -24600.0 -0.18 585352.0 -37300.0 -0.28 -0.3277 -0.9761 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I14 compound treatment 635713.0 13100.0 0.1 715800.0 93200.0 0.71 0.5683 0.7958 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I15 compound treatment 576526.0 -46100.0 -0.34 601337.0 -21300.0 -0.16 -0.3526 -0.9436 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I16 compound treatment 559754.0 -62800.0 -0.46 589429.0 -33200.0 -0.25 -0.5033 -0.9602 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I17 compound treatment 645381.0 22800.0 0.17 556793.0 -65900.0 -0.5 -0.2358 -0.4472 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I18 compound treatment 580208.0 -42400.0 -0.31 588292.0 -34400.0 -0.26 -0.4036 -0.9964 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I19 compound treatment 692977.0 70400.0 0.51 631287.0 8640.0 0.07 0.4105 0.7909 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I20 compound treatment 672978.0 50400.0 0.37 661887.0 39200.0 0.3 0.4714 0.9945 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I21 mock treatment 686490.0 63900.0 0.47 742149.0 120000.0 0.91 0.9724 0.9524 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I22 mock treatment 627195.0 4620.0 0.03 650171.0 27500.0 0.21 0.1717 0.8108 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I23 compound treatment 699920.0 77300.0 0.57 582924.0 -39700.0 -0.3 0.1866 0.291 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 I24 compound treatment 473154.0 -149000.0 -1.09 517463.0 -105000.0 -0.8 -1.3377 -0.9882 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J01 compound treatment 663959.0 41400.0 0.3 576880.0 -45800.0 -0.35 -0.0319 -0.0691 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J02 compound treatment 486733.0 -136000.0 -0.99 501440.0 -121000.0 -0.92 -1.3536 -0.9993 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J03 compound treatment 528818.0 -93800.0 -0.69 573470.0 -49200.0 -0.37 -0.749 -0.9592 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J04 compound treatment 472673.0 -150000.0 -1.1 568652.0 -54000.0 -0.41 -1.0652 -0.9101 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J05 mock treatment 502355.0 -120000.0 -0.88 644498.0 21900.0 0.17 -0.5043 -0.5636 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J06 mock treatment 489186.0 -133000.0 -0.98 598097.0 -24600.0 -0.19 -0.8217 -0.8273 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J07 compound treatment 390112.0 -232000.0 -1.7 395119.0 -228000.0 -1.73 -2.4243 -1.0 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J08 compound treatment 550582.0 -72000.0 -0.53 591457.0 -31200.0 -0.24 -0.5398 -0.935 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J09 compound treatment 461735.0 -161000.0 -1.18 483713.0 -139000.0 -1.06 -1.5781 -0.9985 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J10 compound treatment 497901.0 -125000.0 -0.91 552145.0 -70500.0 -0.54 -1.0234 -0.9678 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J11 compound treatment 584057.0 -38500.0 -0.28 716050.0 93400.0 0.71 0.3025 0.3963 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J12 compound treatment 483346.0 -139000.0 -1.02 420539.0 -202000.0 -1.54 -1.8057 -0.9801 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J13 compound treatment 498737.0 -124000.0 -0.91 517294.0 -105000.0 -0.8 -1.2063 -0.9981 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J14 compound treatment 462969.0 -160000.0 -1.17 590763.0 -31900.0 -0.24 -0.9966 -0.836 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J15 compound treatment 491568.0 -131000.0 -0.96 528286.0 -94400.0 -0.72 -1.1844 -0.9898 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J16 compound treatment 511145.0 -111000.0 -0.81 581509.0 -41100.0 -0.31 -0.7972 -0.9134 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J17 compound treatment 677633.0 55100.0 0.4 733697.0 111000.0 0.84 0.8812 0.9427 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J18 compound treatment 523695.0 -98900.0 -0.72 522815.0 -99800.0 -0.76 -1.0476 -0.9997 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J19 compound treatment 487751.0 -135000.0 -0.99 547184.0 -75500.0 -0.57 -1.1026 -0.9667 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J20 compound treatment 515679.0 -107000.0 -0.78 568201.0 -54400.0 -0.41 -0.8453 -0.9557 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J21 mock treatment 728936.0 106000.0 0.78 697959.0 75300.0 0.57 0.9546 0.9886 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J22 mock treatment 762511.0 140000.0 1.02 594675.0 -28000.0 -0.21 0.5734 0.5486 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J23 compound treatment 734694.0 112000.0 0.82 632752.0 10100.0 0.08 0.6341 0.7699 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 J24 compound treatment 504324.0 -118000.0 -0.86 484726.0 -138000.0 -1.05 -1.3524 -0.9955 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K01 compound treatment 542888.0 -79700.0 -0.58 552260.0 -70400.0 -0.53 -0.7902 -0.9991 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K02 compound treatment 673403.0 50800.0 0.37 687314.0 64700.0 0.49 0.6102 0.9905 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K03 compound treatment 532872.0 -89700.0 -0.66 703202.0 80600.0 0.61 -0.0312 -0.0347 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K04 compound treatment 686626.0 64000.0 0.47 639732.0 17100.0 0.13 0.423 0.8703 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K05 compound treatment 618170.0 -4410.0 -0.03 734568.0 112000.0 0.85 0.5784 0.6798 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K06 compound treatment 583985.0 -38600.0 -0.28 653590.0 30900.0 0.24 -0.0333 -0.0908 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K07 mock treatment 612120.0 -10500.0 -0.08 621271.0 -1380.0 -0.01 -0.0615 -0.7964 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K08 mock treatment 617713.0 -4860.0 -0.04 606459.0 -16200.0 -0.12 -0.1121 -0.8758 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K09 compound treatment 592040.0 -30500.0 -0.22 696040.0 73400.0 0.56 0.2363 0.3935 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K10 compound treatment 737313.0 115000.0 0.84 755329.0 133000.0 1.01 1.306 0.9958 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K11 compound treatment 629716.0 7140.0 0.05 622471.0 -176.0 0.0 0.036 0.6888 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K12 compound treatment 680644.0 58100.0 0.42 741983.0 119000.0 0.91 0.9413 0.9403 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K13 compound treatment 744174.0 122000.0 0.89 741691.0 119000.0 0.9 1.2683 1.0 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K14 compound treatment 251803.0 -371000.0 -2.71 271957.0 -351000.0 -2.66 -3.8011 -1.0 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K15 mock treatment 706486.0 83900.0 0.61 699497.0 76800.0 0.58 0.8467 0.9997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K16 mock treatment 699319.0 76700.0 0.56 612106.0 -10500.0 -0.08 0.3402 0.6001 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K17 compound treatment 687737.0 65200.0 0.48 689256.0 66600.0 0.51 0.6948 0.9995 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K18 compound treatment 469503.0 -153000.0 -1.12 577449.0 -45200.0 -0.34 -1.0344 -0.8834 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K19 compound treatment 617074.0 -5500.0 -0.04 731475.0 109000.0 0.83 0.5561 0.6719 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K20 compound treatment 662687.0 40100.0 0.29 716265.0 93600.0 0.71 0.7103 0.9233 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K21 compound treatment 619327.0 -3250.0 -0.02 680075.0 57400.0 0.44 0.2917 0.6676 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K22 compound treatment 637486.0 14900.0 0.11 727488.0 105000.0 0.8 0.6403 0.7965 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K23 mock treatment 662946.0 40400.0 0.3 661114.0 38500.0 0.29 0.4154 1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 K24 mock treatment 691831.0 69300.0 0.51 591674.0 -31000.0 -0.24 0.1917 0.3433 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L01 compound treatment 643217.0 20600.0 0.15 641855.0 19200.0 0.15 0.2099 0.9999 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L02 compound treatment 472547.0 -150000.0 -1.1 450313.0 -172000.0 -1.31 -1.7016 -0.9961 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L03 compound treatment 625016.0 2440.0 0.02 547209.0 -75400.0 -0.57 -0.3926 -0.6848 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L04 compound treatment 457805.0 -165000.0 -1.2 435939.0 -187000.0 -1.42 -1.855 -0.9967 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L05 compound treatment 663498.0 40900.0 0.3 572599.0 -50000.0 -0.38 -0.0572 -0.1183 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L06 compound treatment 494573.0 -128000.0 -0.94 636839.0 14200.0 0.11 -0.5857 -0.6216 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L07 mock treatment 630123.0 7550.0 0.06 562817.0 -59800.0 -0.45 -0.2824 -0.6167 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L08 mock treatment 579478.0 -43100.0 -0.32 592206.0 -30400.0 -0.23 -0.3864 -0.9884 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L09 compound treatment 677311.0 54700.0 0.4 653708.0 31100.0 0.24 0.4499 0.9682 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L10 compound treatment 541599.0 -81000.0 -0.59 510421.0 -112000.0 -0.85 -1.0216 -0.9841 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L11 compound treatment 624937.0 2360.0 0.02 698946.0 76300.0 0.58 0.4221 0.7278 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L12 compound treatment 598163.0 -24400.0 -0.18 507510.0 -115000.0 -0.87 -0.7447 -0.8342 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L13 compound treatment 689799.0 67200.0 0.49 610964.0 -11700.0 -0.09 0.2849 0.5702 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L14 compound treatment 697539.0 75000.0 0.55 654688.0 32000.0 0.24 0.5598 0.9332 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L15 mock treatment 716526.0 93900.0 0.69 686631.0 64000.0 0.49 0.8295 0.9856 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L16 mock treatment 645727.0 23100.0 0.17 693626.0 71000.0 0.54 0.501 0.8865 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L17 compound treatment 465816.0 -157000.0 -1.15 438363.0 -184000.0 -1.4 -1.8006 -0.9951 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L18 compound treatment 531567.0 -91000.0 -0.67 663459.0 40800.0 0.31 -0.2514 -0.3424 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L19 compound treatment 653546.0 31000.0 0.23 646969.0 24300.0 0.18 0.2908 0.9949 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L20 compound treatment 581787.0 -40800.0 -0.3 650010.0 27400.0 0.21 -0.0639 -0.1759 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L21 compound treatment 651284.0 28700.0 0.21 738655.0 116000.0 0.88 0.7716 0.8517 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L22 compound treatment 489054.0 -134000.0 -0.98 637659.0 15000.0 0.11 -0.6098 -0.6203 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L23 mock treatment 712902.0 90300.0 0.66 612741.0 -9910.0 -0.08 0.4139 0.6225 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 L24 mock treatment 646240.0 23700.0 0.17 652428.0 29800.0 0.23 0.2823 0.9912 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M01 compound treatment 478865.0 -144000.0 -1.05 471275.0 -151000.0 -1.15 -1.5563 -0.999 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M02 compound treatment 541587.0 -81000.0 -0.59 614005.0 -8640.0 -0.07 -0.4652 -0.7807 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M03 compound treatment 588512.0 -34100.0 -0.25 602513.0 -20100.0 -0.15 -0.2843 -0.9726 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M04 compound treatment 646918.0 24300.0 0.18 758207.0 136000.0 1.03 0.8541 0.8172 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M05 compound treatment 540058.0 -82500.0 -0.6 590723.0 -31900.0 -0.24 -0.5982 -0.9198 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M06 compound treatment 725317.0 103000.0 0.75 697598.0 75000.0 0.57 0.9339 0.9906 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M07 compound treatment 453182.0 -169000.0 -1.24 602003.0 -20600.0 -0.16 -0.9869 -0.7903 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M08 compound treatment 501662.0 -121000.0 -0.88 530194.0 -92500.0 -0.7 -1.1219 -0.9935 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M09 mock treatment 700079.0 77500.0 0.57 718688.0 96000.0 0.73 0.9167 0.9922 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M10 mock treatment 669506.0 46900.0 0.34 657944.0 35300.0 0.27 0.4323 0.9925 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M11 compound treatment 497979.0 -125000.0 -0.91 345954.0 -277000.0 -2.1 -2.1306 -0.93 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M12 compound treatment 692419.0 69800.0 0.51 619519.0 -3130.0 -0.02 0.3444 0.6735 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M13 mock treatment 626107.0 3530.0 0.03 674661.0 52000.0 0.4 0.2977 0.7517 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M14 mock treatment 524886.0 -97700.0 -0.71 714520.0 91900.0 0.7 -0.0117 -0.0117 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M15 compound treatment 432440.0 -190000.0 -1.39 498621.0 -124000.0 -0.94 -1.6495 -0.982 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M16 compound treatment 513360.0 -109000.0 -0.8 574758.0 -47900.0 -0.36 -0.822 -0.9366 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M17 compound treatment 684431.0 61900.0 0.45 720584.0 97900.0 0.74 0.8459 0.9715 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M18 compound treatment 727706.0 105000.0 0.77 786172.0 164000.0 1.24 1.422 0.9734 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M19 compound treatment 785993.0 163000.0 1.2 726960.0 104000.0 0.79 1.4054 0.9801 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M20 compound treatment 707823.0 85200.0 0.62 683084.0 60400.0 0.46 0.7655 0.9887 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M21 compound treatment 712745.0 90200.0 0.66 786502.0 164000.0 1.24 1.3465 0.9559 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M22 compound treatment 622807.0 230.0 0.0 720211.0 97600.0 0.74 0.5253 0.7087 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M23 compound treatment 731409.0 109000.0 0.8 811771.0 189000.0 1.44 1.5787 0.9612 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 M24 compound treatment 504672.0 -118000.0 -0.86 514265.0 -108000.0 -0.82 -1.1919 -0.9997 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N01 compound treatment 618930.0 -3650.0 -0.03 641389.0 18700.0 0.14 0.0818 0.5648 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N02 compound treatment 676866.0 54300.0 0.4 666130.0 43500.0 0.33 0.5143 0.9958 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N03 compound treatment 643306.0 20700.0 0.15 679161.0 56500.0 0.43 0.4108 0.9022 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N04 compound treatment 708199.0 85600.0 0.63 573592.0 -49100.0 -0.37 0.1793 0.246 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N05 compound treatment 686740.0 64200.0 0.47 739164.0 117000.0 0.89 0.9577 0.9559 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N06 compound treatment 592528.0 -30000.0 -0.22 517281.0 -105000.0 -0.8 -0.7214 -0.8691 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N07 compound treatment 738967.0 116000.0 0.85 759796.0 137000.0 1.04 1.3386 0.995 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N08 compound treatment 611451.0 -11100.0 -0.08 688601.0 66000.0 0.5 0.2968 0.5846 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N09 mock treatment 592936.0 -29600.0 -0.22 622833.0 186.0 0.0 -0.1523 -0.7025 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N10 mock treatment 590482.0 -32100.0 -0.23 643900.0 21300.0 0.16 -0.0518 -0.1818 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N11 compound treatment 734659.0 112000.0 0.82 601978.0 -20700.0 -0.16 0.4686 0.5614 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N12 compound treatment 699320.0 76700.0 0.56 632660.0 10000.0 0.08 0.4506 0.7957 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N13 mock treatment 541611.0 -81000.0 -0.59 724827.0 102000.0 0.78 0.1302 0.1334 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N14 mock treatment 536403.0 -86200.0 -0.63 689068.0 66400.0 0.5 -0.0888 -0.11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N15 compound treatment 741702.0 119000.0 0.87 701228.0 78600.0 0.6 1.0381 0.983 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N16 compound treatment 691875.0 69300.0 0.51 672798.0 50200.0 0.38 0.6277 0.9901 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N17 compound treatment 660811.0 38200.0 0.28 781002.0 158000.0 1.2 1.0484 0.8488 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N18 compound treatment 647790.0 25200.0 0.18 755367.0 133000.0 1.01 0.8433 0.8228 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N19 compound treatment 748077.0 125000.0 0.92 751132.0 128000.0 0.98 1.3392 0.9995 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N20 compound treatment 439156.0 -183000.0 -1.34 547315.0 -75300.0 -0.57 -1.3532 -0.9279 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N21 compound treatment 759425.0 137000.0 1.0 743465.0 121000.0 0.92 1.3567 0.9991 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N22 compound treatment 669490.0 46900.0 0.34 751026.0 128000.0 0.98 0.9322 0.9017 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N23 compound treatment 619613.0 -2960.0 -0.02 709702.0 87100.0 0.66 0.4523 0.6836 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 N24 compound treatment 653622.0 31000.0 0.23 708139.0 85500.0 0.65 0.6198 0.9008 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O01 compound treatment 515180.0 -107000.0 -0.79 526727.0 -95900.0 -0.73 -1.0706 -0.9993 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O02 compound treatment 594211.0 -28400.0 -0.21 743980.0 121000.0 0.92 0.5051 0.5346 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O03 compound treatment 591870.0 -30700.0 -0.22 665554.0 42900.0 0.33 0.0717 0.1811 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O04 compound treatment 697431.0 74900.0 0.55 702524.0 79900.0 0.61 0.8162 0.9987 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O05 compound treatment 520413.0 -102000.0 -0.75 549103.0 -73500.0 -0.56 -0.9234 -0.9897 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O06 compound treatment 714627.0 92000.0 0.67 779404.0 157000.0 1.19 1.3181 0.9635 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O07 compound treatment 647562.0 25000.0 0.18 663945.0 41300.0 0.31 0.351 0.9669 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O08 compound treatment 556939.0 -65600.0 -0.48 676808.0 54200.0 0.41 -0.0485 -0.0767 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O09 compound treatment 726337.0 104000.0 0.76 793321.0 171000.0 1.3 1.4534 0.9674 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O10 compound treatment 631769.0 9190.0 0.07 616406.0 -6240.0 -0.05 0.014 0.1703 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O11 mock treatment 789694.0 167000.0 1.22 667185.0 44500.0 0.34 1.1034 0.8701 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O12 mock treatment 700671.0 78100.0 0.57 798527.0 176000.0 1.34 1.3486 0.9281 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O13 compound treatment 746127.0 124000.0 0.9 692064.0 69400.0 0.53 1.0118 0.9671 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O14 compound treatment 817680.0 195000.0 1.43 839308.0 217000.0 1.65 2.1727 0.9975 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O15 compound treatment 868151.0 246000.0 1.8 804834.0 182000.0 1.38 2.2486 0.9917 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O16 compound treatment 767497.0 145000.0 1.06 789451.0 167000.0 1.27 1.6454 0.9961 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O17 compound treatment 756755.0 134000.0 0.98 633029.0 10400.0 0.08 0.7496 0.7615 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O18 compound treatment 773768.0 151000.0 1.11 665324.0 42700.0 0.32 1.0111 0.8775 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O19 compound treatment 811149.0 189000.0 1.38 685611.0 63000.0 0.48 1.3134 0.8998 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O20 compound treatment 617651.0 -4930.0 -0.04 499106.0 -124000.0 -0.94 -0.6891 -0.7337 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O21 compound treatment 818142.0 196000.0 1.43 777195.0 155000.0 1.17 1.8415 0.9952 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O22 compound treatment 663487.0 40900.0 0.3 648429.0 25800.0 0.2 0.35 0.9789 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O23 compound treatment 678369.0 55800.0 0.41 758194.0 136000.0 1.03 1.0166 0.9179 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 O24 compound treatment 474770.0 -148000.0 -1.08 577464.0 -45200.0 -0.34 -1.007 -0.888 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P01 compound treatment 556312.0 -66300.0 -0.48 594973.0 -27700.0 -0.21 -0.4913 -0.9301 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P02 compound treatment 710952.0 88400.0 0.65 697083.0 74400.0 0.57 0.8568 0.9978 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P03 compound treatment 672348.0 49800.0 0.36 639764.0 17100.0 0.13 0.3493 0.9038 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P04 compound treatment 622344.0 -233.0 0.0 656836.0 34200.0 0.26 0.1824 0.7024 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P05 compound treatment 651197.0 28600.0 0.21 648112.0 25500.0 0.19 0.2848 0.9992 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P06 compound treatment 620532.0 -2050.0 -0.01 691346.0 68700.0 0.52 0.3585 0.6866 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P07 compound treatment 724058.0 101000.0 0.74 616485.0 -6160.0 -0.05 0.4917 0.6612 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P08 compound treatment 645717.0 23100.0 0.17 682995.0 60300.0 0.46 0.4438 0.9082 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P09 compound treatment 182885.0 -440000.0 -3.22 175886.0 -447000.0 -3.39 -4.6736 -0.9996 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P10 compound treatment 603095.0 -19500.0 -0.14 520710.0 -102000.0 -0.77 -0.6483 -0.8234 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P11 mock treatment 797984.0 175000.0 1.28 728234.0 106000.0 0.8 1.4742 0.9744 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P12 mock treatment 729388.0 107000.0 0.78 680277.0 57600.0 0.44 0.8619 0.9625 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P13 compound treatment 880250.0 258000.0 1.88 568136.0 -54500.0 -0.41 1.0396 0.5389 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P14 compound treatment 822090.0 200000.0 1.46 667625.0 45000.0 0.34 1.2733 0.8497 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P15 compound treatment 706149.0 83600.0 0.61 544871.0 -77800.0 -0.59 0.0144 0.0169 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P16 compound treatment 684397.0 61800.0 0.45 668103.0 45500.0 0.35 0.5639 0.9912 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P17 compound treatment 820309.0 198000.0 1.45 677621.0 55000.0 0.42 1.3178 0.8755 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P18 compound treatment 743851.0 121000.0 0.89 579196.0 -43500.0 -0.33 0.3937 0.416 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P19 compound treatment 824377.0 202000.0 1.48 689513.0 66900.0 0.51 1.4027 0.8987 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P20 compound treatment 687805.0 65200.0 0.48 691120.0 68500.0 0.52 0.7051 0.9991 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P21 compound treatment 782016.0 159000.0 1.17 748777.0 126000.0 0.96 1.502 0.9952 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P22 compound treatment 806143.0 184000.0 1.34 734116.0 111000.0 0.85 1.548 0.9753 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P23 compound treatment 794882.0 172000.0 1.26 872733.0 250000.0 1.9 2.2344 0.9801 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2094 P24 compound treatment 871041.0 248000.0 1.82 803417.0 181000.0 1.37 2.2559 0.9905 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A01 compound treatment 601051.0 36500.0 0.27 606708.0 -39100.0 -0.3 -0.0212 -0.0531 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A02 compound treatment 586353.0 21800.0 0.16 544924.0 -101000.0 -0.77 -0.4291 -0.548 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A03 compound treatment 396647.0 -168000.0 -1.23 311305.0 -335000.0 -2.54 -2.6651 -0.9443 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A04 compound treatment 491871.0 -72600.0 -0.53 560764.0 -85100.0 -0.65 -0.8326 -0.9953 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A05 compound treatment 446205.0 -118000.0 -0.87 505721.0 -140000.0 -1.06 -1.3644 -0.9947 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A06 compound treatment 527697.0 -36800.0 -0.27 561281.0 -84600.0 -0.64 -0.6446 -0.9255 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A07 compound treatment 552190.0 -12300.0 -0.09 671671.0 25800.0 0.2 0.0751 0.3476 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A08 compound treatment 437954.0 -127000.0 -0.93 418187.0 -228000.0 -1.73 -1.8773 -0.9571 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A09 compound treatment 557910.0 -6600.0 -0.05 585701.0 -60100.0 -0.46 -0.3572 -0.7775 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A10 compound treatment 533433.0 -31100.0 -0.23 651536.0 5700.0 0.04 -0.1301 -0.5622 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A11 compound treatment 445503.0 -119000.0 -0.87 467549.0 -178000.0 -1.35 -1.5731 -0.9771 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A12 compound treatment 578224.0 13700.0 0.1 646207.0 373.0 0.0 0.0729 0.7268 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A13 mock treatment 533507.0 -31000.0 -0.23 631644.0 -14200.0 -0.11 -0.2366 -0.9422 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A14 mock treatment 544234.0 -20300.0 -0.15 660493.0 14700.0 0.11 -0.0261 -0.1408 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A15 compound treatment 493082.0 -71400.0 -0.52 713014.0 67200.0 0.51 -0.0085 -0.0116 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A16 compound treatment 552282.0 -12200.0 -0.09 641736.0 -4100.0 -0.03 -0.0853 -0.9002 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A17 compound treatment 627127.0 62600.0 0.46 639325.0 -6510.0 -0.05 0.2888 0.6271 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A18 compound treatment 667640.0 103000.0 0.75 742744.0 96900.0 0.74 1.0539 0.9999 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A19 compound treatment 616393.0 51900.0 0.38 788467.0 143000.0 1.08 1.0345 0.9011 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A20 compound treatment 544511.0 -20000.0 -0.15 683211.0 37400.0 0.28 0.0974 0.3048 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A21 compound treatment 560195.0 -4320.0 -0.03 607095.0 -38700.0 -0.29 -0.2304 -0.7785 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A22 compound treatment 528486.0 -36000.0 -0.26 573177.0 -72700.0 -0.55 -0.5766 -0.9427 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A23 compound treatment 607373.0 42900.0 0.31 599453.0 -46400.0 -0.35 -0.0275 -0.0583 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 A24 compound treatment 674480.0 110000.0 0.8 594280.0 -51600.0 -0.39 0.2917 0.3261 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B01 compound treatment 629554.0 65000.0 0.48 635122.0 -10700.0 -0.08 0.2788 0.5777 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B02 compound treatment 559435.0 -5080.0 -0.04 644511.0 -1320.0 -0.01 -0.0334 -0.8673 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B03 compound treatment 521260.0 -43300.0 -0.32 633579.0 -12300.0 -0.09 -0.2895 -0.878 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B04 compound treatment 582171.0 17700.0 0.13 540241.0 -106000.0 -0.8 -0.4759 -0.5857 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B05 compound treatment 517400.0 -47100.0 -0.34 661813.0 16000.0 0.12 -0.1578 -0.4319 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B06 compound treatment 508981.0 -55500.0 -0.41 622044.0 -23800.0 -0.18 -0.415 -0.9335 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B07 compound treatment 639957.0 75400.0 0.55 624458.0 -21400.0 -0.16 0.2753 0.4787 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B08 compound treatment 559048.0 -5460.0 -0.04 665652.0 19800.0 0.15 0.0782 0.502 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B09 compound treatment 609773.0 45300.0 0.33 643485.0 -2350.0 -0.02 0.2214 0.668 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B10 compound treatment 524098.0 -40400.0 -0.3 579088.0 -66700.0 -0.51 -0.5675 -0.967 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B11 compound treatment 538037.0 -26500.0 -0.19 678714.0 32900.0 0.25 0.0397 0.1257 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B12 compound treatment 585597.0 21100.0 0.15 473659.0 -172000.0 -1.31 -0.8158 -0.6195 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B13 mock treatment 650408.0 85900.0 0.63 639333.0 -6500.0 -0.05 0.4093 0.6495 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B14 mock treatment 549102.0 -15400.0 -0.11 671822.0 26000.0 0.2 0.0599 0.2636 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B15 compound treatment 594873.0 30400.0 0.22 687946.0 42100.0 0.32 0.3832 0.9841 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B16 compound treatment 521999.0 -42500.0 -0.31 664329.0 18500.0 0.14 -0.1205 -0.3532 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B17 compound treatment 706868.0 142000.0 1.04 660940.0 15100.0 0.11 0.8173 0.7803 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B18 compound treatment 554092.0 -10400.0 -0.08 531110.0 -115000.0 -0.87 -0.6701 -0.766 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B19 compound treatment 632229.0 67700.0 0.5 656934.0 11100.0 0.08 0.4098 0.8158 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B20 compound treatment 564967.0 455.0 0.0 638062.0 -7770.0 -0.06 -0.0394 -0.6662 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B21 compound treatment 560263.0 -4250.0 -0.03 686607.0 40800.0 0.31 0.1971 0.633 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B22 compound treatment 611951.0 47400.0 0.35 709814.0 64000.0 0.49 0.589 0.9863 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B23 compound treatment 610531.0 46000.0 0.34 699996.0 54200.0 0.41 0.5289 0.995 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 B24 compound treatment 673415.0 109000.0 0.8 634460.0 -11400.0 -0.09 0.5021 0.6267 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C01 compound treatment 515840.0 -48700.0 -0.36 585328.0 -60500.0 -0.46 -0.5767 -0.992 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C02 compound treatment 557395.0 -7120.0 -0.05 537822.0 -108000.0 -0.82 -0.617 -0.7505 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C03 compound treatment 490761.0 -73800.0 -0.54 654409.0 8580.0 0.07 -0.3353 -0.6172 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C04 compound treatment 107566.0 -457000.0 -3.34 108001.0 -538000.0 -4.09 -5.252 -0.995 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C05 compound treatment 631137.0 66600.0 0.49 685265.0 39400.0 0.3 0.5563 0.9727 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C06 compound treatment 563358.0 -1150.0 -0.01 637265.0 -8570.0 -0.07 -0.052 -0.7922 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C07 compound treatment 565997.0 1480.0 0.01 580089.0 -65700.0 -0.5 -0.3455 -0.6916 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C08 compound treatment 508704.0 -55800.0 -0.41 545346.0 -100000.0 -0.76 -0.8284 -0.957 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C09 compound treatment 588744.0 24200.0 0.18 563405.0 -82400.0 -0.63 -0.3175 -0.4878 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C10 compound treatment 120298.0 -444000.0 -3.25 121549.0 -524000.0 -3.98 -5.1134 -0.9949 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C11 mock treatment 559765.0 -4750.0 -0.03 605964.0 -39900.0 -0.3 -0.2387 -0.783 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C12 mock treatment 568021.0 3510.0 0.03 571482.0 -74400.0 -0.56 -0.3813 -0.6743 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C13 compound treatment 595248.0 30700.0 0.22 678502.0 32700.0 0.25 0.3344 0.9988 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C14 compound treatment 550392.0 -14100.0 -0.1 471146.0 -175000.0 -1.33 -1.0114 -0.7598 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C15 mock treatment 618197.0 53700.0 0.39 711534.0 65700.0 0.5 0.6305 0.9929 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C16 mock treatment 651482.0 87000.0 0.64 660224.0 14400.0 0.11 0.527 0.8167 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C17 compound treatment 606686.0 42200.0 0.31 587920.0 -57900.0 -0.44 -0.093 -0.1731 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C18 compound treatment 605956.0 41400.0 0.3 593552.0 -52300.0 -0.4 -0.0665 -0.1332 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C19 compound treatment 555756.0 -8760.0 -0.06 675013.0 29200.0 0.22 0.1115 0.4831 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C20 compound treatment 627062.0 62500.0 0.46 653789.0 7960.0 0.06 0.3662 0.7936 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C21 compound treatment 667664.0 103000.0 0.75 705984.0 60200.0 0.46 0.8565 0.9712 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C22 compound treatment 655330.0 90800.0 0.66 646138.0 304.0 0.0 0.4713 0.7096 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C23 compound treatment 525571.0 -38900.0 -0.28 566497.0 -79300.0 -0.6 -0.6275 -0.9414 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 C24 compound treatment 642540.0 78000.0 0.57 566572.0 -79300.0 -0.6 -0.0223 -0.0269 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D01 compound treatment 711770.0 147000.0 1.08 590251.0 -55600.0 -0.42 0.4629 0.4002 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D02 compound treatment 514352.0 -50200.0 -0.37 592087.0 -53700.0 -0.41 -0.5481 -0.9986 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D03 compound treatment 600973.0 36500.0 0.27 584692.0 -61100.0 -0.46 -0.1399 -0.2612 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D04 compound treatment 502186.0 -62300.0 -0.46 663572.0 17700.0 0.13 -0.227 -0.4776 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D05 compound treatment 527533.0 -37000.0 -0.27 585996.0 -59800.0 -0.45 -0.5127 -0.9692 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D06 compound treatment 503306.0 -61200.0 -0.45 600393.0 -45400.0 -0.35 -0.5606 -0.9918 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D07 compound treatment 503276.0 -61200.0 -0.45 560626.0 -85200.0 -0.65 -0.7744 -0.9838 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D08 compound treatment 530530.0 -34000.0 -0.25 571759.0 -74100.0 -0.56 -0.5736 -0.9325 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D09 compound treatment 516989.0 -47500.0 -0.35 643041.0 -2790.0 -0.02 -0.2608 -0.7489 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D10 compound treatment 512347.0 -52200.0 -0.38 586588.0 -59200.0 -0.45 -0.588 -0.9966 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D11 mock treatment 570652.0 6140.0 0.04 549550.0 -96300.0 -0.73 -0.4855 -0.6625 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D12 mock treatment 610657.0 46100.0 0.34 578128.0 -67700.0 -0.51 -0.1251 -0.2033 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D13 compound treatment 538053.0 -26500.0 -0.19 604442.0 -41400.0 -0.31 -0.3592 -0.9728 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D14 compound treatment 546957.0 -17600.0 -0.13 637869.0 -7960.0 -0.06 -0.1336 -0.9411 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D15 mock treatment 592884.0 28400.0 0.21 619059.0 -26800.0 -0.2 0.0029 0.0099 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D16 mock treatment 552185.0 -12300.0 -0.09 647640.0 1810.0 0.01 -0.054 -0.5926 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D17 compound treatment 510388.0 -54100.0 -0.4 567753.0 -78100.0 -0.59 -0.6993 -0.9807 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D18 compound treatment 685027.0 121000.0 0.88 519387.0 -126000.0 -0.96 -0.056 -0.043 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D19 compound treatment 619653.0 55100.0 0.4 591998.0 -53800.0 -0.41 -0.004 -0.0071 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D20 compound treatment 596803.0 32300.0 0.24 508797.0 -137000.0 -1.04 -0.5691 -0.5332 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D21 compound treatment 703119.0 139000.0 1.01 700929.0 55100.0 0.42 1.0127 0.9235 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D22 compound treatment 691872.0 127000.0 0.93 684556.0 38700.0 0.29 0.8666 0.8872 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D23 compound treatment 670439.0 106000.0 0.77 664795.0 19000.0 0.14 0.6496 0.8245 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 D24 compound treatment 623493.0 59000.0 0.43 574280.0 -71600.0 -0.54 -0.0794 -0.1144 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E01 mock treatment 526418.0 -38100.0 -0.28 535144.0 -111000.0 -0.84 -0.7916 -0.8936 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E02 mock treatment 533090.0 -31400.0 -0.23 671712.0 25900.0 0.2 -0.0235 -0.0776 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E03 compound treatment 558863.0 -5650.0 -0.04 652125.0 6290.0 0.05 0.0046 0.0725 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E04 compound treatment 516566.0 -47900.0 -0.35 635191.0 -10600.0 -0.08 -0.3051 -0.8479 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E05 compound treatment 615092.0 50600.0 0.37 682364.0 36500.0 0.28 0.4578 0.99 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E06 compound treatment 304991.0 -260000.0 -1.9 383731.0 -262000.0 -1.99 -2.75 -0.9997 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E07 compound treatment 594893.0 30400.0 0.22 636517.0 -9320.0 -0.07 0.1071 0.4591 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E08 compound treatment 486181.0 -78300.0 -0.57 588757.0 -57100.0 -0.43 -0.7117 -0.9906 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E09 mock treatment 499762.0 -64800.0 -0.47 500514.0 -145000.0 -1.1 -1.1155 -0.9286 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E10 mock treatment 554376.0 -10100.0 -0.07 544332.0 -102000.0 -0.77 -0.5977 -0.7715 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E11 compound treatment 516154.0 -48400.0 -0.35 577299.0 -68500.0 -0.52 -0.6182 -0.9822 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E12 compound treatment 592563.0 28100.0 0.21 602318.0 -43500.0 -0.33 -0.0887 -0.228 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E13 compound treatment 560060.0 -4450.0 -0.03 735351.0 89500.0 0.68 0.4578 0.6725 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E14 compound treatment 502444.0 -62100.0 -0.45 730673.0 84800.0 0.64 0.1348 0.171 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E15 compound treatment 128316.0 -436000.0 -3.19 127516.0 -518000.0 -3.94 -5.0399 -0.9945 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E16 compound treatment 526863.0 -37600.0 -0.28 587140.0 -58700.0 -0.45 -0.51 -0.9732 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E17 mock treatment 603550.0 39000.0 0.29 705524.0 59700.0 0.45 0.5225 0.9751 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E18 mock treatment 567698.0 3190.0 0.02 613192.0 -32600.0 -0.25 -0.1589 -0.6379 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E19 compound treatment 599788.0 35300.0 0.26 648301.0 2470.0 0.02 0.1957 0.7565 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E20 compound treatment 673480.0 109000.0 0.8 666891.0 21100.0 0.16 0.6766 0.8324 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E21 compound treatment 610042.0 45500.0 0.33 756050.0 110000.0 0.84 0.8275 0.9184 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E22 compound treatment 617843.0 53300.0 0.39 719270.0 73400.0 0.56 0.6703 0.9847 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E23 compound treatment 548433.0 -16100.0 -0.12 628059.0 -17800.0 -0.14 -0.1786 -0.9976 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 E24 compound treatment 548674.0 -15800.0 -0.12 606039.0 -39800.0 -0.3 -0.2957 -0.9133 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F01 mock treatment 541675.0 -22800.0 -0.17 571460.0 -74400.0 -0.57 -0.5176 -0.8785 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F02 mock treatment 485768.0 -78700.0 -0.58 620084.0 -25700.0 -0.2 -0.5455 -0.897 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F03 compound treatment 580028.0 15500.0 0.11 650714.0 4880.0 0.04 0.1065 0.8918 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F04 compound treatment 556391.0 -8120.0 -0.06 640907.0 -4930.0 -0.04 -0.0685 -0.9752 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F05 compound treatment 603744.0 39200.0 0.29 691799.0 46000.0 0.35 0.4498 0.9952 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F06 compound treatment 468097.0 -96400.0 -0.71 623374.0 -22500.0 -0.17 -0.6192 -0.8536 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F07 compound treatment 488724.0 -75800.0 -0.55 593826.0 -52000.0 -0.4 -0.6713 -0.9862 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F08 compound treatment 486448.0 -78100.0 -0.57 613365.0 -32500.0 -0.25 -0.5781 -0.9296 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F09 mock treatment 521527.0 -43000.0 -0.31 528093.0 -118000.0 -0.89 -0.8548 -0.9016 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F10 mock treatment 499112.0 -65400.0 -0.48 599574.0 -46300.0 -0.35 -0.5867 -0.9885 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F11 compound treatment 586984.0 22500.0 0.16 678309.0 32500.0 0.25 0.2907 0.9805 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F12 compound treatment 573107.0 8590.0 0.06 515022.0 -131000.0 -0.99 -0.6582 -0.6611 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F13 compound treatment 559746.0 -4770.0 -0.03 605016.0 -40800.0 -0.31 -0.2439 -0.7817 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F14 compound treatment 489947.0 -74600.0 -0.55 633289.0 -12500.0 -0.1 -0.453 -0.8183 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F15 compound treatment 241852.0 -323000.0 -2.36 323067.0 -323000.0 -2.45 -3.4023 -0.9998 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F16 compound treatment 545370.0 -19100.0 -0.14 612080.0 -33800.0 -0.26 -0.2803 -0.9595 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F17 mock treatment 580975.0 16500.0 0.12 522436.0 -123000.0 -0.94 -0.5777 -0.6113 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F18 mock treatment 567831.0 3320.0 0.02 627145.0 -18700.0 -0.14 -0.0832 -0.5778 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F19 compound treatment 606119.0 41600.0 0.3 541046.0 -105000.0 -0.8 -0.3477 -0.408 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F20 compound treatment 609253.0 44700.0 0.33 595950.0 -49900.0 -0.38 -0.0366 -0.0731 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F21 compound treatment 669220.0 105000.0 0.77 655336.0 9500.0 0.07 0.5925 0.7704 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F22 compound treatment 647495.0 83000.0 0.61 626190.0 -19600.0 -0.15 0.3236 0.5178 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F23 compound treatment 562959.0 -1550.0 -0.01 638408.0 -7430.0 -0.06 -0.0479 -0.8328 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 F24 compound treatment 631313.0 66800.0 0.49 615893.0 -29900.0 -0.23 0.1846 0.3426 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G01 compound treatment 485669.0 -78800.0 -0.58 592185.0 -53600.0 -0.41 -0.6959 -0.9856 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G02 compound treatment 574471.0 9960.0 0.07 592398.0 -53400.0 -0.41 -0.2355 -0.5711 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G03 mock treatment 563230.0 -1280.0 -0.01 533625.0 -112000.0 -0.85 -0.6094 -0.7148 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G04 mock treatment 405200.0 -159000.0 -1.17 633521.0 -12300.0 -0.09 -0.89 -0.7614 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G05 compound treatment 567176.0 2660.0 0.02 599269.0 -46600.0 -0.35 -0.2364 -0.6672 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G06 compound treatment 530585.0 -33900.0 -0.25 500498.0 -145000.0 -1.1 -0.9561 -0.8449 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G07 compound treatment 559395.0 -5120.0 -0.04 623372.0 -22500.0 -0.17 -0.1471 -0.8422 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G08 compound treatment 502913.0 -61600.0 -0.45 684926.0 39100.0 0.3 -0.1085 -0.2012 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G09 compound treatment 570883.0 6370.0 0.05 689654.0 43800.0 0.33 0.2683 0.7983 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G10 compound treatment 587635.0 23100.0 0.17 601974.0 -43900.0 -0.33 -0.116 -0.3105 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G11 compound treatment 557810.0 -6700.0 -0.05 592198.0 -53600.0 -0.41 -0.3228 -0.7865 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G12 compound treatment 534701.0 -29800.0 -0.22 590503.0 -55300.0 -0.42 -0.4514 -0.9533 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G13 compound treatment 542295.0 -22200.0 -0.16 704141.0 58300.0 0.44 0.1983 0.4203 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G14 compound treatment 611970.0 47500.0 0.35 575263.0 -70600.0 -0.54 -0.1337 -0.2093 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G15 compound treatment 561709.0 -2800.0 -0.02 620024.0 -25800.0 -0.2 -0.1531 -0.7768 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G16 compound treatment 536094.0 -28400.0 -0.21 534404.0 -111000.0 -0.85 -0.7455 -0.8553 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G17 compound treatment 496207.0 -68300.0 -0.5 691421.0 45600.0 0.35 -0.1083 -0.1782 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G18 compound treatment 583383.0 18900.0 0.14 489484.0 -156000.0 -1.19 -0.7423 -0.6208 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G19 mock treatment 560038.0 -4470.0 -0.03 565507.0 -80300.0 -0.61 -0.4546 -0.744 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G20 mock treatment 549657.0 -14900.0 -0.11 548474.0 -97400.0 -0.74 -0.5998 -0.8024 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G21 compound treatment 697066.0 133000.0 0.97 661561.0 15700.0 0.12 0.7699 0.7883 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G22 compound treatment 779066.0 215000.0 1.57 801569.0 156000.0 1.18 1.9461 0.9903 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G23 compound treatment 621496.0 57000.0 0.42 742305.0 96500.0 0.73 0.8129 0.9642 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 G24 compound treatment 519491.0 -45000.0 -0.33 688236.0 42400.0 0.32 -0.005 -0.0109 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H01 compound treatment 601477.0 37000.0 0.27 777764.0 132000.0 1.0 0.8998 0.8669 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H02 compound treatment 524537.0 -40000.0 -0.29 519525.0 -126000.0 -0.96 -0.8852 -0.8825 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H03 mock treatment 539764.0 -24700.0 -0.18 547405.0 -98400.0 -0.75 -0.6567 -0.8536 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H04 mock treatment 467707.0 -96800.0 -0.71 622743.0 -23100.0 -0.18 -0.6246 -0.8564 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H05 compound treatment 601589.0 37100.0 0.27 567656.0 -78200.0 -0.59 -0.2282 -0.3496 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H06 compound treatment 529377.0 -35100.0 -0.26 628677.0 -17200.0 -0.13 -0.2739 -0.9505 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H07 compound treatment 508178.0 -56300.0 -0.41 634039.0 -11800.0 -0.09 -0.3547 -0.8412 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H08 compound treatment 474604.0 -89900.0 -0.66 589328.0 -56500.0 -0.43 -0.7685 -0.9786 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H09 compound treatment 621828.0 57300.0 0.42 702594.0 56800.0 0.43 0.6013 0.9999 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H10 compound treatment 464283.0 -100000.0 -0.73 600398.0 -45400.0 -0.35 -0.7624 -0.941 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H11 compound treatment 502514.0 -62000.0 -0.45 674455.0 28600.0 0.22 -0.1669 -0.3318 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H12 compound treatment 495483.0 -69000.0 -0.5 535495.0 -110000.0 -0.84 -0.9497 -0.9705 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H13 compound treatment 604980.0 40500.0 0.3 695563.0 49700.0 0.38 0.4764 0.9927 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H14 compound treatment 504773.0 -59700.0 -0.44 560461.0 -85400.0 -0.65 -0.7675 -0.9815 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H15 compound treatment 624542.0 60000.0 0.44 609004.0 -36800.0 -0.28 0.1126 0.2163 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H16 compound treatment 544298.0 -20200.0 -0.15 611245.0 -34600.0 -0.26 -0.2903 -0.963 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H17 compound treatment 600655.0 36100.0 0.26 694017.0 48200.0 0.37 0.4457 0.9872 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H18 compound treatment 587617.0 23100.0 0.17 601193.0 -44600.0 -0.34 -0.1203 -0.3176 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H19 mock treatment 669616.0 105000.0 0.77 628997.0 -16800.0 -0.13 0.4531 0.5814 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H20 mock treatment 543884.0 -20600.0 -0.15 628994.0 -16800.0 -0.13 -0.1971 -0.9966 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H21 compound treatment 608872.0 44400.0 0.32 715399.0 69600.0 0.53 0.6031 0.9725 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H22 compound treatment 595153.0 30600.0 0.22 665427.0 19600.0 0.15 0.2637 0.9803 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H23 compound treatment 530581.0 -33900.0 -0.25 693123.0 47300.0 0.36 0.0786 0.1799 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 H24 compound treatment 506524.0 -58000.0 -0.42 607905.0 -37900.0 -0.29 -0.5036 -0.9823 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I01 compound treatment 509276.0 -55200.0 -0.4 589030.0 -56800.0 -0.43 -0.5908 -0.9995 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I02 compound treatment 615751.0 51200.0 0.37 638410.0 -7420.0 -0.06 0.2251 0.594 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I03 compound treatment 519126.0 -45400.0 -0.33 605693.0 -40100.0 -0.3 -0.4503 -0.9991 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I04 compound treatment 517230.0 -47300.0 -0.35 660890.0 15100.0 0.11 -0.1636 -0.4493 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I05 mock treatment 477333.0 -87200.0 -0.64 707022.0 61200.0 0.46 -0.1221 -0.1548 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I06 mock treatment 498658.0 -65900.0 -0.48 611602.0 -34200.0 -0.26 -0.5244 -0.9582 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I07 compound treatment 536475.0 -28000.0 -0.21 674296.0 28500.0 0.22 0.0079 0.0265 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I08 compound treatment 510670.0 -53800.0 -0.39 664535.0 18700.0 0.14 -0.178 -0.4251 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I09 compound treatment 415032.0 -149000.0 -1.09 479621.0 -166000.0 -1.26 -1.6658 -0.9974 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I10 compound treatment 582261.0 17700.0 0.13 603707.0 -42100.0 -0.32 -0.1345 -0.3895 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I11 compound treatment 537890.0 -26600.0 -0.19 748792.0 103000.0 0.78 0.4154 0.5154 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I12 compound treatment 519132.0 -45400.0 -0.33 661797.0 16000.0 0.12 -0.1489 -0.4215 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I13 compound treatment 558798.0 -5710.0 -0.04 694175.0 48300.0 0.37 0.2301 0.6226 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I14 compound treatment 607743.0 43200.0 0.32 667800.0 22000.0 0.17 0.3416 0.9554 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I15 compound treatment 610147.0 45600.0 0.33 825420.0 180000.0 1.36 1.2007 0.8549 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I16 compound treatment 575393.0 10900.0 0.08 732453.0 86600.0 0.66 0.5216 0.7869 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I17 compound treatment 755798.0 191000.0 1.4 863442.0 218000.0 1.65 2.1581 0.9965 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I18 compound treatment 539892.0 -24600.0 -0.18 775514.0 130000.0 0.99 0.5693 0.5685 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I19 compound treatment 574329.0 9820.0 0.07 564323.0 -81500.0 -0.62 -0.3871 -0.621 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I20 compound treatment 675911.0 111000.0 0.81 782297.0 136000.0 1.04 1.3091 0.9929 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I21 mock treatment 543114.0 -21400.0 -0.16 619436.0 -26400.0 -0.2 -0.2525 -0.9925 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I22 mock treatment 644715.0 80200.0 0.59 714507.0 68700.0 0.52 0.7836 0.9983 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I23 compound treatment 621147.0 56600.0 0.41 626295.0 -19500.0 -0.15 0.1879 0.4271 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 I24 compound treatment 514104.0 -50400.0 -0.37 691379.0 45500.0 0.35 -0.016 -0.0317 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J01 compound treatment 604113.0 39600.0 0.29 707638.0 61800.0 0.47 0.5368 0.973 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J02 compound treatment 551966.0 -12500.0 -0.09 504217.0 -142000.0 -1.08 -0.8256 -0.7646 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J03 compound treatment 447571.0 -117000.0 -0.86 692891.0 47100.0 0.36 -0.3519 -0.3797 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J04 compound treatment 450770.0 -114000.0 -0.83 592151.0 -53700.0 -0.41 -0.8765 -0.9462 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J05 mock treatment 473375.0 -91100.0 -0.67 696208.0 50400.0 0.38 -0.2007 -0.2611 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J06 mock treatment 523752.0 -40800.0 -0.3 572507.0 -73300.0 -0.56 -0.6047 -0.9571 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J07 compound treatment 518704.0 -45800.0 -0.34 570066.0 -75800.0 -0.58 -0.6439 -0.9668 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J08 compound treatment 472278.0 -92200.0 -0.67 613636.0 -32200.0 -0.24 -0.6499 -0.9058 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J09 compound treatment 136631.0 -428000.0 -3.13 147858.0 -498000.0 -3.78 -4.8876 -0.9956 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J10 compound treatment 524468.0 -40000.0 -0.29 564701.0 -81100.0 -0.62 -0.6429 -0.9421 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J11 compound treatment 583102.0 18600.0 0.14 736155.0 90300.0 0.69 0.5813 0.8311 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J12 compound treatment 514560.0 -50000.0 -0.37 587139.0 -58700.0 -0.45 -0.5736 -0.9951 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J13 compound treatment 119205.0 -445000.0 -3.26 118893.0 -527000.0 -4.0 -5.1333 -0.9948 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J14 compound treatment 614868.0 50400.0 0.37 578139.0 -67700.0 -0.51 -0.1032 -0.1632 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J15 compound treatment 477376.0 -87100.0 -0.64 702524.0 56700.0 0.43 -0.1461 -0.1899 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J16 compound treatment 655865.0 91400.0 0.67 727963.0 82100.0 0.62 0.9136 0.9994 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J17 compound treatment 300638.0 -264000.0 -1.93 340545.0 -305000.0 -2.32 -3.0045 -0.9958 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J18 compound treatment 511177.0 -53300.0 -0.39 711541.0 65700.0 0.5 0.0772 0.1218 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J19 compound treatment 626968.0 62500.0 0.46 647460.0 1630.0 0.01 0.3317 0.726 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J20 compound treatment 531257.0 -33300.0 -0.24 594039.0 -51800.0 -0.39 -0.4502 -0.9733 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J21 mock treatment 647802.0 83300.0 0.61 725854.0 80000.0 0.61 0.8606 1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J22 mock treatment 628330.0 63800.0 0.47 741805.0 96000.0 0.73 0.8455 0.9768 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J23 compound treatment 605184.0 40700.0 0.3 793452.0 148000.0 1.12 1.0033 0.8648 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 J24 compound treatment 560572.0 -3940.0 -0.03 618466.0 -27400.0 -0.21 -0.1674 -0.7975 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K01 compound treatment 396401.0 -168000.0 -1.23 446075.0 -200000.0 -1.52 -1.9424 -0.9945 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K02 compound treatment 537172.0 -27300.0 -0.2 621896.0 -23900.0 -0.18 -0.27 -0.9989 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K03 compound treatment 522602.0 -41900.0 -0.31 599104.0 -46700.0 -0.35 -0.4677 -0.9973 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K04 compound treatment 568213.0 3700.0 0.03 458059.0 -188000.0 -1.43 -0.9895 -0.6936 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K05 compound treatment 572739.0 8230.0 0.06 790684.0 145000.0 1.1 0.8206 0.7447 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K06 compound treatment 243079.0 -321000.0 -2.35 321552.0 -324000.0 -2.46 -3.4041 -0.9997 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K07 mock treatment 606635.0 42100.0 0.31 676794.0 31000.0 0.24 0.3841 0.9911 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K08 mock treatment 541848.0 -22700.0 -0.17 656973.0 11100.0 0.08 -0.0574 -0.3082 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K09 compound treatment 542015.0 -22500.0 -0.16 674098.0 28300.0 0.21 0.0355 0.1312 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K10 compound treatment 525204.0 -39300.0 -0.29 694960.0 49100.0 0.37 0.0606 0.1287 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K11 compound treatment 675423.0 111000.0 0.81 747463.0 102000.0 0.77 1.1195 0.9997 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K12 compound treatment 150183.0 -414000.0 -3.03 165744.0 -480000.0 -3.65 -4.7215 -0.9958 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K13 compound treatment 583470.0 19000.0 0.14 713763.0 67900.0 0.52 0.4629 0.8664 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K14 compound treatment 632671.0 68200.0 0.5 686342.0 40500.0 0.31 0.5701 0.9731 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K15 mock treatment 580239.0 15700.0 0.12 757288.0 111000.0 0.85 0.68 0.7958 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K16 mock treatment 537699.0 -26800.0 -0.2 742522.0 96700.0 0.73 0.3807 0.5008 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K17 compound treatment 568093.0 3580.0 0.03 653242.0 7410.0 0.06 0.0583 0.9394 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K18 compound treatment 119615.0 -445000.0 -3.25 120644.0 -525000.0 -3.99 -5.1218 -0.9949 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K19 compound treatment 588386.0 23900.0 0.17 686745.0 40900.0 0.31 0.3432 0.9628 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K20 compound treatment 633162.0 68600.0 0.5 610490.0 -35300.0 -0.27 0.1651 0.2901 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K21 compound treatment 619274.0 54800.0 0.4 759279.0 113000.0 0.86 0.8926 0.9392 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K22 compound treatment 696026.0 132000.0 0.96 753800.0 108000.0 0.82 1.26 0.9969 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K23 mock treatment 478413.0 -86100.0 -0.63 621971.0 -23900.0 -0.18 -0.5734 -0.8751 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 K24 mock treatment 537774.0 -26700.0 -0.2 585884.0 -59900.0 -0.46 -0.4603 -0.9287 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L01 compound treatment 635925.0 71400.0 0.52 776789.0 131000.0 0.99 1.0727 0.9547 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L02 compound treatment 532296.0 -32200.0 -0.24 678638.0 32800.0 0.25 0.0096 0.0281 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L03 compound treatment 533915.0 -30600.0 -0.22 654211.0 8380.0 0.06 -0.1132 -0.4867 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L04 compound treatment 513042.0 -51500.0 -0.38 620407.0 -25400.0 -0.19 -0.4027 -0.9519 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L05 compound treatment 530067.0 -34400.0 -0.25 700586.0 54800.0 0.42 0.116 0.2385 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L06 compound treatment 575096.0 10600.0 0.08 622739.0 -23100.0 -0.18 -0.0693 -0.3615 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L07 mock treatment 526638.0 -37900.0 -0.28 567662.0 -78200.0 -0.59 -0.6158 -0.9397 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L08 mock treatment 498119.0 -66400.0 -0.49 629242.0 -16600.0 -0.13 -0.4325 -0.8621 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L09 compound treatment 130785.0 -434000.0 -3.17 122596.0 -523000.0 -3.97 -5.0536 -0.9937 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L10 compound treatment 520633.0 -43900.0 -0.32 551623.0 -94200.0 -0.72 -0.733 -0.9345 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L11 compound treatment 525785.0 -38700.0 -0.28 779703.0 134000.0 1.02 0.5188 0.4915 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L12 compound treatment 600096.0 35600.0 0.26 657184.0 11400.0 0.09 0.245 0.8936 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L13 compound treatment 563799.0 -713.0 -0.01 791508.0 146000.0 1.11 0.7788 0.7038 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L14 compound treatment 508433.0 -56100.0 -0.41 628174.0 -17700.0 -0.13 -0.3849 -0.8919 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L15 mock treatment 621273.0 56800.0 0.42 717658.0 71800.0 0.55 0.6793 0.9909 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L16 mock treatment 581681.0 17200.0 0.13 714880.0 69000.0 0.52 0.4597 0.8523 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L17 compound treatment 592862.0 28300.0 0.21 672990.0 27200.0 0.21 0.2925 1.0 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L18 compound treatment 538613.0 -25900.0 -0.19 674806.0 29000.0 0.22 0.0217 0.0747 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L19 compound treatment 635018.0 70500.0 0.52 641101.0 -4730.0 -0.04 0.3392 0.6562 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L20 compound treatment 585887.0 21400.0 0.16 701608.0 55800.0 0.42 0.4101 0.9081 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L21 compound treatment 548754.0 -15800.0 -0.12 752572.0 107000.0 0.81 0.4919 0.6006 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L22 compound treatment 597478.0 33000.0 0.24 651854.0 6020.0 0.05 0.2028 0.8265 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L23 mock treatment 526364.0 -38100.0 -0.28 717712.0 71900.0 0.55 0.1888 0.308 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 L24 mock treatment 522895.0 -41600.0 -0.3 679305.0 33500.0 0.25 -0.0354 -0.0893 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M01 compound treatment 553418.0 -11100.0 -0.08 659355.0 13500.0 0.1 0.0153 0.1166 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M02 compound treatment 522122.0 -42400.0 -0.31 719479.0 73600.0 0.56 0.1764 0.2758 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M03 compound treatment 491996.0 -72500.0 -0.53 660322.0 14500.0 0.11 -0.2972 -0.5487 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M04 compound treatment 585604.0 21100.0 0.15 769004.0 123000.0 0.94 0.7707 0.8127 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M05 compound treatment 121857.0 -443000.0 -3.24 116644.0 -529000.0 -4.02 -5.1317 -0.9942 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M06 compound treatment 612062.0 47500.0 0.35 706100.0 60300.0 0.46 0.5696 0.9908 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M07 compound treatment 591893.0 27400.0 0.2 763792.0 118000.0 0.9 0.7752 0.8443 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M08 compound treatment 636013.0 71500.0 0.52 791205.0 145000.0 1.1 1.1506 0.9417 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M09 mock treatment 567952.0 3440.0 0.03 698599.0 52800.0 0.4 0.3012 0.75 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M10 mock treatment 669211.0 105000.0 0.77 784997.0 139000.0 1.06 1.289 0.9875 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M11 compound treatment 138393.0 -426000.0 -3.12 143920.0 -502000.0 -3.81 -4.8997 -0.995 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M12 compound treatment 119734.0 -445000.0 -3.25 123317.0 -523000.0 -3.97 -5.1068 -0.9951 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M13 mock treatment 623164.0 58700.0 0.43 794941.0 149000.0 1.13 1.1043 0.9117 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M14 mock treatment 584357.0 19800.0 0.15 653146.0 7310.0 0.06 0.1419 0.9132 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M15 compound treatment 658613.0 94100.0 0.69 842005.0 196000.0 1.49 1.5404 0.9384 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M16 compound treatment 592929.0 28400.0 0.21 900607.0 255000.0 1.94 1.5155 0.7786 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M17 compound treatment 663086.0 98600.0 0.72 640482.0 -5350.0 -0.04 0.481 0.6662 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M18 compound treatment 671162.0 107000.0 0.78 881798.0 236000.0 1.79 1.819 0.9305 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M19 compound treatment 664462.0 99900.0 0.73 884476.0 239000.0 1.81 1.7988 0.9202 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M20 compound treatment 571689.0 7180.0 0.05 682610.0 36800.0 0.28 0.2347 0.8255 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M21 compound treatment 598569.0 34100.0 0.25 842172.0 196000.0 1.49 1.2308 0.8139 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M22 compound treatment 744206.0 180000.0 1.31 741689.0 95900.0 0.73 1.4441 0.9612 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M23 compound treatment 663634.0 99100.0 0.72 761054.0 115000.0 0.88 1.1315 0.9956 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 M24 compound treatment 521440.0 -43100.0 -0.31 653840.0 8010.0 0.06 -0.1797 -0.5602 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N01 compound treatment 550116.0 -14400.0 -0.11 845756.0 200000.0 1.52 0.9995 0.6565 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N02 compound treatment 564667.0 155.0 0.0 720596.0 74800.0 0.57 0.4024 0.7085 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N03 compound treatment 669243.0 105000.0 0.77 771475.0 126000.0 0.95 1.2165 0.994 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N04 compound treatment 540355.0 -24200.0 -0.18 727366.0 81500.0 0.62 0.313 0.486 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N05 compound treatment 595300.0 30800.0 0.23 801795.0 156000.0 1.18 0.997 0.8267 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N06 compound treatment 603296.0 38800.0 0.28 712071.0 66200.0 0.5 0.5564 0.9632 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N07 compound treatment 654244.0 89700.0 0.66 946275.0 300000.0 2.28 2.0779 0.875 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N08 compound treatment 621519.0 57000.0 0.42 748133.0 102000.0 0.78 0.8443 0.9574 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N09 mock treatment 464285.0 -100000.0 -0.73 755804.0 110000.0 0.84 0.0724 0.0652 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N10 mock treatment 654864.0 90400.0 0.66 869548.0 224000.0 1.7 1.669 0.9153 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N11 compound treatment 676385.0 112000.0 0.82 787563.0 142000.0 1.08 1.3398 0.9908 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N12 compound treatment 588139.0 23600.0 0.17 810038.0 164000.0 1.25 1.0042 0.7974 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N13 mock treatment 553975.0 -10500.0 -0.08 704042.0 58200.0 0.44 0.2582 0.5752 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N14 mock treatment 646096.0 81600.0 0.6 677382.0 31500.0 0.24 0.5914 0.9197 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N15 compound treatment 118000.0 -447000.0 -3.27 123650.0 -522000.0 -3.97 -5.114 -0.9953 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N16 compound treatment 750531.0 186000.0 1.36 693890.0 48100.0 0.37 1.2201 0.8662 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N17 compound treatment 692123.0 128000.0 0.93 740025.0 94200.0 0.72 1.1659 0.9914 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N18 compound treatment 571384.0 6870.0 0.05 691292.0 45500.0 0.35 0.2797 0.8016 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N19 compound treatment 733778.0 169000.0 1.24 763800.0 118000.0 0.9 1.509 0.9874 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N20 compound treatment 586749.0 22200.0 0.16 813661.0 168000.0 1.27 1.0165 0.7909 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N21 compound treatment 667842.0 103000.0 0.76 755055.0 109000.0 0.83 1.121 0.9989 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N22 compound treatment 686439.0 122000.0 0.89 666263.0 20400.0 0.16 0.7402 0.8179 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N23 compound treatment 823113.0 259000.0 1.89 837585.0 192000.0 1.46 2.3673 0.9917 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 N24 compound treatment 579317.0 14800.0 0.11 647139.0 1310.0 0.01 0.0836 0.7687 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O01 compound treatment 683290.0 119000.0 0.87 772257.0 126000.0 0.96 1.2933 0.9987 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O02 compound treatment 607793.0 43300.0 0.32 640965.0 -4870.0 -0.04 0.1977 0.6203 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O03 compound treatment 668015.0 104000.0 0.76 857854.0 212000.0 1.61 1.6741 0.9407 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O04 compound treatment 559812.0 -4700.0 -0.03 751901.0 106000.0 0.81 0.5455 0.6763 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O05 compound treatment 638124.0 73600.0 0.54 839887.0 194000.0 1.47 1.4231 0.9068 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O06 compound treatment 634874.0 70400.0 0.51 755375.0 110000.0 0.83 0.9523 0.9733 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O07 compound treatment 655195.0 90700.0 0.66 830901.0 185000.0 1.41 1.4631 0.9412 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O08 compound treatment 603171.0 38700.0 0.28 814994.0 169000.0 1.29 1.1086 0.8425 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O09 compound treatment 562863.0 -1650.0 -0.01 885514.0 240000.0 1.82 1.279 0.7024 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O10 compound treatment 635232.0 70700.0 0.52 804650.0 159000.0 1.21 1.2188 0.9285 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O11 mock treatment 639155.0 74600.0 0.55 872589.0 227000.0 1.72 1.6041 0.8877 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O12 mock treatment 660796.0 96300.0 0.7 781745.0 136000.0 1.03 1.228 0.9826 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O13 compound treatment 644447.0 79900.0 0.58 791760.0 146000.0 1.11 1.1972 0.9553 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O14 compound treatment 718900.0 154000.0 1.13 781983.0 136000.0 1.03 1.5297 0.999 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O15 compound treatment 510721.0 -53800.0 -0.39 606871.0 -39000.0 -0.3 -0.4875 -0.9902 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O16 compound treatment 665702.0 101000.0 0.74 803693.0 158000.0 1.2 1.3712 0.9731 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O17 compound treatment 627138.0 62600.0 0.46 689355.0 43500.0 0.33 0.5576 0.9872 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O18 compound treatment 695957.0 131000.0 0.96 890469.0 245000.0 1.86 1.9938 0.9529 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O19 compound treatment 695852.0 131000.0 0.96 842704.0 197000.0 1.5 1.7367 0.9771 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O20 compound treatment 721215.0 157000.0 1.15 836757.0 191000.0 1.45 1.8359 0.9932 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O21 compound treatment 832996.0 268000.0 1.96 769694.0 124000.0 0.94 2.0537 0.9433 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O22 compound treatment 658475.0 94000.0 0.69 810580.0 165000.0 1.25 1.3709 0.9601 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O23 compound treatment 729187.0 165000.0 1.2 750399.0 105000.0 0.79 1.4133 0.9796 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 O24 compound treatment 567031.0 2520.0 0.02 725721.0 79900.0 0.61 0.4422 0.7282 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P01 compound treatment 648892.0 84400.0 0.62 963750.0 318000.0 2.42 2.1441 0.8601 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P02 compound treatment 635723.0 71200.0 0.52 799334.0 154000.0 1.17 1.1928 0.934 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P03 compound treatment 752003.0 187000.0 1.37 918961.0 273000.0 2.07 2.4367 0.9798 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P04 compound treatment 670679.0 106000.0 0.78 757179.0 111000.0 0.85 1.1471 0.9991 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P05 compound treatment 108940.0 -456000.0 -3.33 116489.0 -529000.0 -4.02 -5.1993 -0.9956 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P06 compound treatment 620545.0 56000.0 0.41 913970.0 268000.0 2.04 1.7301 0.8327 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P07 compound treatment 566290.0 1780.0 0.01 858019.0 212000.0 1.61 1.149 0.7128 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P08 compound treatment 624640.0 60100.0 0.44 935815.0 290000.0 2.2 1.8686 0.8318 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P09 compound treatment 689516.0 125000.0 0.91 939414.0 294000.0 2.23 2.2234 0.9225 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P10 compound treatment 678042.0 114000.0 0.83 729711.0 83900.0 0.64 1.0376 0.9915 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P11 mock treatment 721784.0 157000.0 1.15 775878.0 130000.0 0.99 1.5118 0.9971 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P12 mock treatment 798383.0 234000.0 1.71 662974.0 17100.0 0.13 1.3015 0.7587 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P13 compound treatment 655100.0 90600.0 0.66 737227.0 91400.0 0.69 0.9594 0.9997 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P14 compound treatment 682129.0 118000.0 0.86 766945.0 121000.0 0.92 1.2588 0.9994 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P15 compound treatment 705316.0 141000.0 1.03 771853.0 126000.0 0.96 1.4051 0.9993 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P16 compound treatment 675687.0 111000.0 0.81 778136.0 132000.0 1.01 1.2856 0.9945 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P17 compound treatment 790728.0 226000.0 1.65 801574.0 156000.0 1.18 2.0064 0.9865 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P18 compound treatment 772021.0 208000.0 1.52 727899.0 82100.0 0.62 1.5139 0.9228 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P19 compound treatment 460307.0 -104000.0 -0.76 613076.0 -32800.0 -0.25 -0.7148 -0.8917 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P20 compound treatment 762784.0 198000.0 1.45 741614.0 95800.0 0.73 1.5398 0.9491 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P21 compound treatment 781714.0 217000.0 1.59 743568.0 97700.0 0.74 1.6482 0.94 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P22 compound treatment 864041.0 300000.0 2.19 852045.0 206000.0 1.57 2.6566 0.9865 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P23 compound treatment 843712.0 279000.0 2.04 795327.0 149000.0 1.14 2.2468 0.9617 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2095 P24 compound treatment 714629.0 150000.0 1.1 740203.0 94400.0 0.72 1.2832 0.9787 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A01 compound treatment 667327.0 13100.0 0.1 563708.0 -96200.0 -0.73 -0.4489 -0.6093 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A02 compound treatment 587293.0 -67000.0 -0.49 748097.0 88200.0 0.67 0.1277 0.1539 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A03 compound treatment 574908.0 -79300.0 -0.58 601768.0 -58100.0 -0.44 -0.7223 -0.9909 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A04 compound treatment 550946.0 -103000.0 -0.76 639119.0 -20700.0 -0.16 -0.6456 -0.8366 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A05 compound treatment 646510.0 -7740.0 -0.06 554986.0 -105000.0 -0.8 -0.6034 -0.7554 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A06 compound treatment 562872.0 -91400.0 -0.67 574215.0 -85700.0 -0.65 -0.9326 -0.9999 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A07 compound treatment 543782.0 -110000.0 -0.81 550588.0 -109000.0 -0.83 -1.1582 -0.9999 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A08 compound treatment 517146.0 -137000.0 -1.0 576304.0 -83600.0 -0.63 -1.1578 -0.9757 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A09 compound treatment 556504.0 -97700.0 -0.71 610320.0 -49500.0 -0.38 -0.7716 -0.9551 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A10 compound treatment 541792.0 -112000.0 -0.82 607566.0 -52300.0 -0.4 -0.8625 -0.9443 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A11 compound treatment 608956.0 -45300.0 -0.33 614330.0 -45500.0 -0.35 -0.4788 -0.9998 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A12 compound treatment 550637.0 -104000.0 -0.76 549525.0 -110000.0 -0.84 -1.1285 -0.9987 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A13 mock treatment 606808.0 -47400.0 -0.35 515143.0 -145000.0 -1.1 -1.0227 -0.8871 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A14 mock treatment 672249.0 18000.0 0.13 531795.0 -128000.0 -0.97 -0.5949 -0.6059 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A15 compound treatment 692596.0 38400.0 0.28 637737.0 -22100.0 -0.17 0.0794 0.243 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A16 compound treatment 558825.0 -95400.0 -0.7 538732.0 -121000.0 -0.92 -1.1441 -0.9907 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A17 compound treatment 570021.0 -84200.0 -0.62 602471.0 -57400.0 -0.44 -0.7438 -0.9857 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A18 compound treatment 612940.0 -41300.0 -0.3 568386.0 -91500.0 -0.69 -0.705 -0.9304 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A19 compound treatment 594234.0 -60000.0 -0.44 604330.0 -55500.0 -0.42 -0.6086 -0.9998 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A20 compound treatment 589598.0 -64600.0 -0.47 655062.0 -4800.0 -0.04 -0.3601 -0.7594 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A21 compound treatment 615770.0 -38500.0 -0.28 647714.0 -12200.0 -0.09 -0.2642 -0.8923 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A22 compound treatment 600536.0 -53700.0 -0.39 589573.0 -70300.0 -0.53 -0.6553 -0.9886 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A23 compound treatment 569155.0 -85100.0 -0.62 463747.0 -196000.0 -1.49 -1.4935 -0.925 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 A24 compound treatment 620202.0 -34000.0 -0.25 581502.0 -78400.0 -0.6 -0.597 -0.9252 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B01 compound treatment 638646.0 -15600.0 -0.11 661775.0 1910.0 0.01 -0.0704 -0.6122 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B02 compound treatment 509496.0 -145000.0 -1.06 580371.0 -79500.0 -0.6 -1.1755 -0.9646 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B03 compound treatment 627872.0 -26400.0 -0.19 667020.0 7160.0 0.05 -0.0979 -0.4888 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B04 compound treatment 458882.0 -195000.0 -1.43 567242.0 -92600.0 -0.7 -1.5078 -0.9468 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B05 compound treatment 621962.0 -32300.0 -0.24 665081.0 5220.0 0.04 -0.1389 -0.5803 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B06 compound treatment 513553.0 -141000.0 -1.03 547550.0 -112000.0 -0.85 -1.3309 -0.9957 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B07 compound treatment 600274.0 -54000.0 -0.39 561342.0 -98500.0 -0.75 -0.8083 -0.9553 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B08 compound treatment 552359.0 -102000.0 -0.75 579659.0 -80200.0 -0.61 -0.9577 -0.995 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B09 compound treatment 652448.0 -1800.0 -0.01 602906.0 -57000.0 -0.43 -0.3153 -0.7283 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B10 compound treatment 548679.0 -106000.0 -0.77 582781.0 -77100.0 -0.59 -0.96 -0.9907 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B11 compound treatment 693685.0 39400.0 0.29 657486.0 -2380.0 -0.02 0.1912 0.6615 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B12 compound treatment 288619.0 -366000.0 -2.67 254553.0 -405000.0 -3.08 -4.0679 -0.9975 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B13 mock treatment 561276.0 -93000.0 -0.68 647969.0 -11900.0 -0.09 -0.5447 -0.7941 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B14 mock treatment 641683.0 -12600.0 -0.09 668113.0 8250.0 0.06 -0.0207 -0.1858 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B15 compound treatment 629819.0 -24400.0 -0.18 616819.0 -43000.0 -0.33 -0.3575 -0.9595 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B16 compound treatment 540830.0 -113000.0 -0.83 595252.0 -64600.0 -0.49 -0.9336 -0.9687 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B17 compound treatment 675973.0 21700.0 0.16 655762.0 -4100.0 -0.03 0.0903 0.5578 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B18 compound treatment 316968.0 -337000.0 -2.47 279138.0 -381000.0 -2.89 -3.7893 -0.9969 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B19 compound treatment 642564.0 -11700.0 -0.09 728084.0 68200.0 0.52 0.306 0.5827 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B20 compound treatment 624697.0 -29500.0 -0.22 612910.0 -47000.0 -0.36 -0.405 -0.9712 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B21 compound treatment 657506.0 3260.0 0.02 627770.0 -32100.0 -0.24 -0.1555 -0.6349 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B22 compound treatment 624485.0 -29800.0 -0.22 624158.0 -35700.0 -0.27 -0.3457 -0.994 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B23 compound treatment 641019.0 -13200.0 -0.1 705013.0 45100.0 0.34 0.1741 0.4886 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 B24 compound treatment 623940.0 -30300.0 -0.22 688761.0 28900.0 0.22 -0.0015 -0.0048 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C01 compound treatment 571662.0 -82600.0 -0.6 567943.0 -91900.0 -0.7 -0.9208 -0.9974 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C02 compound treatment 566521.0 -87700.0 -0.64 600109.0 -59800.0 -0.45 -0.7746 -0.9857 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C03 compound treatment 678109.0 23900.0 0.17 638163.0 -21700.0 -0.16 0.0068 0.0284 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C04 compound treatment 622976.0 -31300.0 -0.23 677806.0 17900.0 0.14 -0.0653 -0.2454 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C05 compound treatment 608231.0 -46000.0 -0.34 574853.0 -85000.0 -0.65 -0.6946 -0.9538 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C06 compound treatment 543453.0 -111000.0 -0.81 665495.0 5630.0 0.04 -0.5427 -0.6688 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C07 compound treatment 611866.0 -42400.0 -0.31 560665.0 -99200.0 -0.75 -0.752 -0.9229 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C08 compound treatment 638537.0 -15700.0 -0.11 579558.0 -80300.0 -0.61 -0.5126 -0.8257 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C09 compound treatment 601231.0 -53000.0 -0.39 593617.0 -66200.0 -0.5 -0.63 -0.9917 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C10 compound treatment 601926.0 -52300.0 -0.38 612182.0 -47700.0 -0.36 -0.5267 -0.9996 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C11 mock treatment 643516.0 -10700.0 -0.08 647580.0 -12300.0 -0.09 -0.1215 -0.9963 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C12 mock treatment 647552.0 -6690.0 -0.05 602981.0 -56900.0 -0.43 -0.3402 -0.7822 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C13 compound treatment 632115.0 -22100.0 -0.16 561661.0 -98200.0 -0.75 -0.642 -0.8409 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C14 compound treatment 613401.0 -40800.0 -0.3 580859.0 -79000.0 -0.6 -0.6356 -0.9481 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C15 mock treatment 655021.0 775.0 0.01 612707.0 -47200.0 -0.36 -0.2493 -0.6958 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C16 mock treatment 690458.0 36200.0 0.26 628669.0 -31200.0 -0.24 0.0197 0.0554 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C17 compound treatment 676268.0 22000.0 0.16 648745.0 -11100.0 -0.08 0.0541 0.2977 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C18 compound treatment 682402.0 28200.0 0.21 657579.0 -2290.0 -0.02 0.1333 0.6452 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C19 compound treatment 633802.0 -20400.0 -0.15 596854.0 -63000.0 -0.48 -0.4442 -0.8858 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C20 compound treatment 656098.0 1850.0 0.01 650729.0 -9140.0 -0.07 -0.0395 -0.5586 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C21 compound treatment 725499.0 71300.0 0.52 645099.0 -14800.0 -0.11 0.2891 0.5425 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C22 compound treatment 655287.0 1040.0 0.01 656164.0 -3700.0 -0.03 -0.0145 -0.4977 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C23 compound treatment 591691.0 -62600.0 -0.46 602467.0 -57400.0 -0.44 -0.6318 -0.9997 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 C24 compound treatment 697789.0 43500.0 0.32 628228.0 -31600.0 -0.24 0.0552 0.1384 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D01 compound treatment 637431.0 -16800.0 -0.12 758848.0 99000.0 0.75 0.4448 0.5837 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D02 compound treatment 582557.0 -71700.0 -0.52 677874.0 18000.0 0.14 -0.274 -0.5057 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D03 compound treatment 701093.0 46800.0 0.34 658008.0 -1860.0 -0.01 0.2323 0.6774 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D04 compound treatment 340965.0 -313000.0 -2.29 368494.0 -291000.0 -2.21 -3.1852 -0.9999 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D05 compound treatment 620058.0 -34200.0 -0.25 690215.0 30400.0 0.23 -0.0138 -0.0405 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D06 compound treatment 597085.0 -57200.0 -0.42 532859.0 -127000.0 -0.96 -0.9778 -0.9299 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D07 compound treatment 585985.0 -68300.0 -0.5 634378.0 -25500.0 -0.19 -0.4899 -0.915 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D08 compound treatment 541999.0 -112000.0 -0.82 546232.0 -114000.0 -0.86 -1.1909 -0.9997 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D09 compound treatment 495713.0 -159000.0 -1.16 492195.0 -168000.0 -1.27 -1.7205 -0.9989 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D10 compound treatment 534873.0 -119000.0 -0.87 595528.0 -64300.0 -0.49 -0.9629 -0.9624 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D11 mock treatment 634178.0 -20100.0 -0.15 532362.0 -128000.0 -0.97 -0.7887 -0.8051 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D12 mock treatment 560183.0 -94100.0 -0.69 608195.0 -51700.0 -0.39 -0.764 -0.9646 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D13 compound treatment 638135.0 -16100.0 -0.12 654082.0 -5780.0 -0.04 -0.1144 -0.9096 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D14 compound treatment 572648.0 -81600.0 -0.6 586941.0 -72900.0 -0.55 -0.8137 -0.9993 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D15 mock treatment 637014.0 -17200.0 -0.13 649633.0 -10200.0 -0.08 -0.1441 -0.973 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D16 mock treatment 642343.0 -11900.0 -0.09 656674.0 -3190.0 -0.02 -0.0787 -0.8709 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D17 compound treatment 658633.0 4390.0 0.03 593218.0 -66600.0 -0.51 -0.3353 -0.661 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D18 compound treatment 639574.0 -14700.0 -0.11 640229.0 -19600.0 -0.15 -0.1813 -0.9869 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D19 compound treatment 507618.0 -147000.0 -1.07 546217.0 -114000.0 -0.86 -1.3687 -0.9942 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D20 compound treatment 568205.0 -86000.0 -0.63 578401.0 -81500.0 -0.62 -0.8825 -1.0 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D21 compound treatment 741344.0 87100.0 0.64 768545.0 109000.0 0.83 1.0342 0.9918 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D22 compound treatment 623759.0 -30500.0 -0.22 738044.0 78200.0 0.59 0.2623 0.4135 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D23 compound treatment 633591.0 -20700.0 -0.15 686375.0 26500.0 0.2 0.0356 0.1414 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 D24 compound treatment 580439.0 -73800.0 -0.54 609806.0 -50100.0 -0.38 -0.6506 -0.9853 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E01 mock treatment 467538.0 -187000.0 -1.37 607678.0 -52200.0 -0.4 -1.2458 -0.8762 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E02 mock treatment 643499.0 -10700.0 -0.08 637348.0 -22500.0 -0.17 -0.1765 -0.9377 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E03 compound treatment 706874.0 52600.0 0.38 663801.0 3940.0 0.03 0.2933 0.7598 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E04 compound treatment 626782.0 -27500.0 -0.2 511684.0 -148000.0 -1.13 -0.938 -0.8203 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E05 compound treatment 517425.0 -137000.0 -1.0 666759.0 6890.0 0.05 -0.6705 -0.6692 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E06 compound treatment 629819.0 -24400.0 -0.18 596699.0 -63200.0 -0.48 -0.4656 -0.9094 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E07 compound treatment 692525.0 38300.0 0.28 629805.0 -30100.0 -0.23 0.0365 0.101 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E08 compound treatment 537839.0 -116000.0 -0.85 665047.0 5180.0 0.04 -0.5741 -0.6737 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E09 mock treatment 569333.0 -84900.0 -0.62 633998.0 -25900.0 -0.2 -0.578 -0.8875 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E10 mock treatment 666406.0 12200.0 0.09 623053.0 -36800.0 -0.28 -0.1349 -0.4596 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E11 compound treatment 569757.0 -84500.0 -0.62 656443.0 -3420.0 -0.03 -0.4553 -0.7362 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E12 compound treatment 666717.0 12500.0 0.09 620682.0 -39200.0 -0.3 -0.146 -0.4689 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E13 compound treatment 536752.0 -117000.0 -0.86 668220.0 8360.0 0.06 -0.5627 -0.6531 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E14 compound treatment 686992.0 32700.0 0.24 623805.0 -36100.0 -0.27 -0.0244 -0.067 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E15 compound treatment 716429.0 62200.0 0.45 641652.0 -18200.0 -0.14 0.2237 0.4707 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E16 compound treatment 666319.0 12100.0 0.09 652263.0 -7600.0 -0.06 0.0216 0.2047 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E17 mock treatment 549422.0 -105000.0 -0.77 631169.0 -28700.0 -0.22 -0.6962 -0.8736 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E18 mock treatment 702053.0 47800.0 0.35 679107.0 19200.0 0.15 0.3506 0.9251 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E19 compound treatment 585269.0 -69000.0 -0.5 663126.0 3260.0 0.02 -0.3392 -0.6716 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E20 compound treatment 626605.0 -27600.0 -0.2 665668.0 5800.0 0.04 -0.1118 -0.5402 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E21 compound treatment 634422.0 -19800.0 -0.14 694220.0 34400.0 0.26 0.082 0.2748 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E22 compound treatment 633717.0 -20500.0 -0.15 550115.0 -110000.0 -0.83 -0.6957 -0.8212 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E23 compound treatment 625982.0 -28300.0 -0.21 601407.0 -58500.0 -0.44 -0.4602 -0.9394 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 E24 compound treatment 184670.0 -470000.0 -3.43 309245.0 -351000.0 -2.66 -4.3117 -0.9921 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F01 mock treatment 646703.0 -7540.0 -0.06 556296.0 -104000.0 -0.79 -0.5954 -0.7548 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F02 mock treatment 654924.0 678.0 0.0 613929.0 -45900.0 -0.35 -0.2432 -0.697 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F03 compound treatment 705704.0 51500.0 0.38 719289.0 59400.0 0.45 0.5853 0.9959 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F04 compound treatment 658053.0 3810.0 0.03 661930.0 2070.0 0.02 0.0308 0.9632 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F05 compound treatment 598149.0 -56100.0 -0.41 541200.0 -119000.0 -0.9 -0.9275 -0.9365 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F06 compound treatment 516837.0 -137000.0 -1.0 513435.0 -146000.0 -1.11 -1.4971 -0.9987 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F07 compound treatment 601902.0 -52300.0 -0.38 714706.0 54800.0 0.42 0.0239 0.0423 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F08 compound treatment 532004.0 -122000.0 -0.89 573122.0 -86700.0 -0.66 -1.0981 -0.9887 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F09 mock treatment 544491.0 -110000.0 -0.8 610218.0 -49600.0 -0.38 -0.8342 -0.9407 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F10 mock treatment 515061.0 -139000.0 -1.02 588743.0 -71100.0 -0.54 -1.1018 -0.9561 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F11 compound treatment 672148.0 17900.0 0.13 705743.0 45900.0 0.35 0.339 0.9106 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F12 compound treatment 626709.0 -27500.0 -0.2 633931.0 -25900.0 -0.2 -0.2817 -0.9999 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F13 compound treatment 616595.0 -37700.0 -0.28 762050.0 102000.0 0.78 0.3542 0.43 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F14 compound treatment 528037.0 -126000.0 -0.92 629160.0 -30700.0 -0.23 -0.8176 -0.8588 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F15 compound treatment 697605.0 43400.0 0.32 688919.0 29100.0 0.22 0.3803 0.9843 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F16 compound treatment 589799.0 -64400.0 -0.47 626170.0 -33700.0 -0.26 -0.5143 -0.9589 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F17 mock treatment 672609.0 18400.0 0.13 633509.0 -26400.0 -0.2 -0.0466 -0.1934 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F18 mock treatment 726024.0 71800.0 0.52 708137.0 48300.0 0.37 0.6305 0.9846 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F19 compound treatment 694557.0 40300.0 0.29 656932.0 -2930.0 -0.02 0.1927 0.6518 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F20 compound treatment 780720.0 126000.0 0.92 705082.0 45200.0 0.34 0.8969 0.909 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F21 compound treatment 657828.0 3580.0 0.03 701610.0 41700.0 0.32 0.2428 0.7629 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F22 compound treatment 640608.0 -13600.0 -0.1 646390.0 -13500.0 -0.1 -0.1429 -0.9999 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F23 compound treatment 603290.0 -51000.0 -0.37 676181.0 16300.0 0.12 -0.1759 -0.4478 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 F24 compound treatment 618286.0 -36000.0 -0.26 621131.0 -38700.0 -0.29 -0.394 -0.9984 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G01 compound treatment 564005.0 -90200.0 -0.66 594797.0 -65100.0 -0.49 -0.8162 -0.9899 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G02 compound treatment 645680.0 -8570.0 -0.06 547679.0 -112000.0 -0.85 -0.6469 -0.757 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G03 mock treatment 607416.0 -46800.0 -0.34 639039.0 -20800.0 -0.16 -0.354 -0.9385 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G04 mock treatment 589180.0 -65100.0 -0.48 593699.0 -66200.0 -0.5 -0.6919 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G05 compound treatment 595246.0 -59000.0 -0.43 671677.0 11800.0 0.09 -0.2416 -0.5483 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G06 compound treatment 698638.0 44400.0 0.32 674948.0 15100.0 0.11 0.3106 0.9021 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G07 compound treatment 622719.0 -31500.0 -0.23 611130.0 -48700.0 -0.37 -0.4248 -0.974 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G08 compound treatment 605828.0 -48400.0 -0.35 716994.0 57100.0 0.43 0.0565 0.1009 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G09 compound treatment 645660.0 -8590.0 -0.06 547362.0 -113000.0 -0.85 -0.6487 -0.757 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G10 compound treatment 583402.0 -70800.0 -0.52 666422.0 6560.0 0.05 -0.3311 -0.6362 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G11 compound treatment 689142.0 34900.0 0.26 675537.0 15700.0 0.12 0.2646 0.9398 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G12 compound treatment 631613.0 -22600.0 -0.17 676213.0 16300.0 0.12 -0.0292 -0.1412 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G13 compound treatment 563649.0 -90600.0 -0.66 691051.0 31200.0 0.24 -0.301 -0.4277 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G14 compound treatment 599713.0 -54500.0 -0.4 665499.0 5630.0 0.04 -0.2517 -0.6276 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G15 compound treatment 701495.0 47200.0 0.35 694530.0 34700.0 0.26 0.4305 0.991 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G16 compound treatment 668033.0 13800.0 0.1 623330.0 -36500.0 -0.28 -0.125 -0.4232 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G17 compound treatment 702893.0 48600.0 0.36 716338.0 56500.0 0.43 0.5549 0.9957 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G18 compound treatment 659289.0 5040.0 0.04 599673.0 -60200.0 -0.46 -0.2973 -0.648 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G19 mock treatment 675534.0 21300.0 0.16 655687.0 -4180.0 -0.03 0.0876 0.5516 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G20 mock treatment 693885.0 39600.0 0.29 546041.0 -114000.0 -0.86 -0.4065 -0.4457 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G21 compound treatment 656168.0 1920.0 0.01 662480.0 2620.0 0.02 0.024 0.9857 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G22 compound treatment 752874.0 98600.0 0.72 682135.0 22300.0 0.17 0.6296 0.8499 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G23 compound treatment 598165.0 -56100.0 -0.41 615381.0 -44500.0 -0.34 -0.529 -0.9954 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 G24 compound treatment 666380.0 12100.0 0.09 689354.0 29500.0 0.22 0.2212 0.9178 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H01 compound treatment 613184.0 -41100.0 -0.3 692803.0 32900.0 0.25 -0.0354 -0.0906 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H02 compound treatment 716592.0 62300.0 0.46 502463.0 -157000.0 -1.2 -0.5231 -0.4088 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H03 mock treatment 584277.0 -70000.0 -0.51 513550.0 -146000.0 -1.11 -1.1478 -0.938 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H04 mock treatment 765660.0 111000.0 0.81 667447.0 7580.0 0.06 0.6169 0.7552 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H05 compound treatment 619525.0 -34700.0 -0.25 451471.0 -208000.0 -1.58 -1.299 -0.8102 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H06 compound treatment 547073.0 -107000.0 -0.78 666282.0 6420.0 0.05 -0.5197 -0.6618 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H07 compound treatment 639046.0 -15200.0 -0.11 524172.0 -136000.0 -1.03 -0.8075 -0.7788 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H08 compound treatment 596923.0 -57300.0 -0.42 650156.0 -9710.0 -0.07 -0.3486 -0.8189 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H09 compound treatment 687772.0 33500.0 0.25 691936.0 32100.0 0.24 0.3456 1.0 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H10 compound treatment 307828.0 -346000.0 -2.53 309117.0 -351000.0 -2.66 -3.6755 -0.9997 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H11 compound treatment 607716.0 -46500.0 -0.34 576083.0 -83800.0 -0.64 -0.6907 -0.957 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H12 compound treatment 625270.0 -29000.0 -0.21 669491.0 9630.0 0.07 -0.0981 -0.4378 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H13 compound treatment 530482.0 -124000.0 -0.91 638798.0 -21100.0 -0.16 -0.7532 -0.8194 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H14 compound treatment 641358.0 -12900.0 -0.09 776042.0 116000.0 0.88 0.5574 0.628 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H15 compound treatment 570541.0 -83700.0 -0.61 675383.0 15500.0 0.12 -0.3495 -0.5606 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H16 compound treatment 473087.0 -181000.0 -1.32 489840.0 -170000.0 -1.29 -1.8501 -0.9999 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H17 compound treatment 584674.0 -69600.0 -0.51 641863.0 -18000.0 -0.14 -0.4565 -0.8664 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H18 compound treatment 273715.0 -381000.0 -2.78 253383.0 -406000.0 -3.09 -4.1513 -0.9987 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H19 mock treatment 706397.0 52200.0 0.38 579776.0 -80100.0 -0.61 -0.1605 -0.2236 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H20 mock treatment 669993.0 15700.0 0.12 690350.0 30500.0 0.23 0.2452 0.948 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H21 compound treatment 664870.0 10600.0 0.08 635662.0 -24200.0 -0.18 -0.0751 -0.3761 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H22 compound treatment 613211.0 -41000.0 -0.3 638816.0 -21000.0 -0.16 -0.3253 -0.9566 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H23 compound treatment 681673.0 27400.0 0.2 662810.0 2950.0 0.02 0.1576 0.7811 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 H24 compound treatment 730763.0 76500.0 0.56 677309.0 17400.0 0.13 0.4894 0.851 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I01 compound treatment 625656.0 -28600.0 -0.21 584301.0 -75600.0 -0.57 -0.5538 -0.9064 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I02 compound treatment 566098.0 -88100.0 -0.64 593269.0 -66600.0 -0.51 -0.8136 -0.9928 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I03 compound treatment 609251.0 -45000.0 -0.33 628999.0 -30900.0 -0.23 -0.3985 -0.9862 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I04 compound treatment 651372.0 -2870.0 -0.02 674704.0 14800.0 0.11 0.0649 0.5655 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I05 mock treatment 535432.0 -119000.0 -0.87 674650.0 14800.0 0.11 -0.535 -0.6106 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I06 mock treatment 553688.0 -101000.0 -0.74 685794.0 25900.0 0.2 -0.3807 -0.5001 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I07 compound treatment 615663.0 -38600.0 -0.28 736798.0 76900.0 0.58 0.2137 0.3294 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I08 compound treatment 750282.0 96000.0 0.7 669088.0 9220.0 0.07 0.5462 0.7738 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I09 compound treatment 673865.0 19600.0 0.14 853072.0 193000.0 1.47 1.1393 0.7725 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I10 compound treatment 572698.0 -81500.0 -0.6 750532.0 90700.0 0.69 0.0653 0.0717 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I11 compound treatment 715454.0 61200.0 0.45 744498.0 84600.0 0.64 0.7711 0.9843 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I12 compound treatment 699861.0 45600.0 0.33 898834.0 239000.0 1.82 1.5196 0.8233 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I13 compound treatment 760613.0 106000.0 0.78 757362.0 97500.0 0.74 1.0738 0.9997 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I14 compound treatment 628310.0 -25900.0 -0.19 663473.0 3610.0 0.03 -0.1147 -0.5987 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I15 compound treatment 657599.0 3350.0 0.02 692725.0 32900.0 0.25 0.1939 0.7728 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I16 compound treatment 719644.0 65400.0 0.48 716660.0 56800.0 0.43 0.6433 0.9987 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I17 compound treatment 587129.0 -67100.0 -0.49 729791.0 69900.0 0.53 0.0286 0.0395 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I18 compound treatment 733087.0 78800.0 0.58 726956.0 67100.0 0.51 0.7681 0.9981 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I19 compound treatment 658195.0 3950.0 0.03 680736.0 20900.0 0.16 0.1325 0.8224 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I20 compound treatment 761451.0 107000.0 0.78 658021.0 -1840.0 -0.01 0.5445 0.6944 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I21 mock treatment 695934.0 41700.0 0.3 680397.0 20500.0 0.16 0.3259 0.9516 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I22 mock treatment 665912.0 11700.0 0.09 658850.0 -1020.0 -0.01 0.0549 0.6406 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I23 compound treatment 684407.0 30200.0 0.22 691581.0 31700.0 0.24 0.3263 0.999 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 I24 compound treatment 670063.0 15800.0 0.12 659874.0 9.0 0.0 0.0818 0.7075 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J01 compound treatment 572939.0 -81300.0 -0.59 572344.0 -87500.0 -0.66 -0.8906 -0.9984 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J02 compound treatment 749575.0 95300.0 0.7 665877.0 6010.0 0.05 0.5253 0.7518 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J03 compound treatment 467950.0 -186000.0 -1.36 444977.0 -215000.0 -1.63 -2.1177 -0.996 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J04 compound treatment 587383.0 -66900.0 -0.49 630613.0 -29300.0 -0.22 -0.5029 -0.9363 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J05 mock treatment 584647.0 -69600.0 -0.51 548999.0 -111000.0 -0.84 -0.9554 -0.9709 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J06 mock treatment 549718.0 -105000.0 -0.76 674013.0 14100.0 0.11 -0.4645 -0.6018 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J07 compound treatment 546373.0 -108000.0 -0.79 427605.0 -232000.0 -1.76 -1.8055 -0.9341 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J08 compound treatment 601481.0 -52800.0 -0.39 607606.0 -52300.0 -0.4 -0.5536 -0.9999 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J09 compound treatment 714162.0 59900.0 0.44 613746.0 -46100.0 -0.35 0.0621 0.1107 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J10 compound treatment 654272.0 26.1 0.0 666756.0 6890.0 0.05 0.0372 0.7097 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J11 compound treatment 604773.0 -49500.0 -0.36 709886.0 50000.0 0.38 0.0129 0.0245 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J12 compound treatment 619809.0 -34400.0 -0.25 693439.0 33600.0 0.26 0.0023 0.0063 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J13 compound treatment 583080.0 -71200.0 -0.52 738893.0 79000.0 0.6 0.0565 0.0711 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J14 compound treatment 234615.0 -420000.0 -3.07 240620.0 -419000.0 -3.18 -4.422 -0.9998 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J15 compound treatment 586196.0 -68000.0 -0.5 787106.0 127000.0 0.97 0.3316 0.305 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J16 compound treatment 251704.0 -403000.0 -2.94 190533.0 -469000.0 -3.57 -4.6027 -0.9955 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J17 compound treatment 571742.0 -82500.0 -0.6 725676.0 65800.0 0.5 -0.0731 -0.0933 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J18 compound treatment 172551.0 -482000.0 -3.52 409675.0 -250000.0 -1.9 -3.8349 -0.9581 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J19 compound treatment 758100.0 104000.0 0.76 682593.0 22700.0 0.17 0.6591 0.8463 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J20 compound treatment 124917.0 -529000.0 -3.87 119526.0 -540000.0 -4.1 -5.6398 -0.9996 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J21 mock treatment 734293.0 80000.0 0.59 716842.0 57000.0 0.43 0.72 0.989 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J22 mock treatment 743041.0 88800.0 0.65 703085.0 43200.0 0.33 0.6913 0.9501 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J23 compound treatment 649414.0 -4830.0 -0.04 713640.0 53800.0 0.41 0.2639 0.6435 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 J24 compound treatment 622592.0 -31700.0 -0.23 599204.0 -60700.0 -0.46 -0.4895 -0.9493 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K01 compound treatment 638035.0 -16200.0 -0.12 596973.0 -62900.0 -0.48 -0.4217 -0.8566 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K02 compound treatment 657697.0 3450.0 0.03 680237.0 20400.0 0.15 0.1273 0.8117 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K03 compound treatment 669407.0 15200.0 0.11 725284.0 65400.0 0.5 0.4298 0.8441 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K04 compound treatment 664359.0 10100.0 0.07 546147.0 -114000.0 -0.86 -0.5586 -0.6442 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K05 compound treatment 720574.0 66300.0 0.49 775351.0 115000.0 0.88 0.9634 0.961 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K06 compound treatment 635596.0 -18600.0 -0.14 707958.0 48100.0 0.37 0.1619 0.4152 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K07 mock treatment 643633.0 -10600.0 -0.08 622069.0 -37800.0 -0.29 -0.2579 -0.8671 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K08 mock treatment 690757.0 36500.0 0.27 690819.0 31000.0 0.24 0.3551 0.998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K09 compound treatment 618850.0 -35400.0 -0.26 848709.0 189000.0 1.43 0.8314 0.5703 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K10 compound treatment 540499.0 -114000.0 -0.83 717327.0 57500.0 0.44 -0.2795 -0.2976 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K11 compound treatment 845735.0 191000.0 1.4 755856.0 96000.0 0.73 1.5059 0.9538 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K12 compound treatment 757570.0 103000.0 0.76 738192.0 78300.0 0.6 0.9551 0.993 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K13 compound treatment 757403.0 103000.0 0.75 720451.0 60600.0 0.46 0.8589 0.9719 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K14 compound treatment 610981.0 -43300.0 -0.32 727487.0 67600.0 0.51 0.1395 0.2312 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K15 mock treatment 720207.0 66000.0 0.48 673835.0 14000.0 0.11 0.4161 0.8425 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K16 mock treatment 530623.0 -124000.0 -0.9 727916.0 68100.0 0.52 -0.2737 -0.2628 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K17 compound treatment 654101.0 -145.0 0.0 606678.0 -53200.0 -0.4 -0.2865 -0.709 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K18 compound treatment 517299.0 -137000.0 -1.0 691339.0 31500.0 0.24 -0.5391 -0.5236 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K19 compound treatment 564000.0 -90200.0 -0.66 699679.0 39800.0 0.3 -0.2528 -0.3482 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K20 compound treatment 706891.0 52600.0 0.38 689734.0 29900.0 0.23 0.4327 0.9682 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K21 compound treatment 714356.0 60100.0 0.44 734100.0 74200.0 0.56 0.7096 0.9924 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K22 compound treatment 654358.0 112.0 0.0 680460.0 20600.0 0.16 0.1112 0.7108 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K23 mock treatment 636512.0 -17700.0 -0.13 624767.0 -35100.0 -0.27 -0.2802 -0.9452 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 K24 mock treatment 599211.0 -55000.0 -0.4 616829.0 -43000.0 -0.33 -0.5158 -0.9947 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L01 compound treatment 703169.0 48900.0 0.36 681330.0 21500.0 0.16 0.3683 0.9367 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L02 compound treatment 640123.0 -14100.0 -0.1 610044.0 -49800.0 -0.38 -0.3407 -0.8683 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L03 compound treatment 638890.0 -15400.0 -0.11 429303.0 -231000.0 -1.75 -1.3179 -0.7509 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L04 compound treatment 678415.0 24200.0 0.18 632167.0 -27700.0 -0.21 -0.0238 -0.0866 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L05 compound treatment 735648.0 81400.0 0.6 666008.0 6140.0 0.05 0.4539 0.7602 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L06 compound treatment 648251.0 -5990.0 -0.04 749116.0 89300.0 0.68 0.4484 0.66 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L07 mock treatment 691583.0 37300.0 0.27 791346.0 131000.0 1.0 0.8994 0.8685 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L08 mock treatment 650464.0 -3780.0 -0.03 702381.0 42500.0 0.32 0.2088 0.6442 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L09 compound treatment 414822.0 -239000.0 -1.75 472121.0 -188000.0 -1.43 -2.2466 -0.9948 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L10 compound treatment 661525.0 7280.0 0.05 749990.0 90100.0 0.68 0.5218 0.7598 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L11 compound treatment 630338.0 -23900.0 -0.17 719362.0 59500.0 0.45 0.196 0.4044 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L12 compound treatment 776094.0 122000.0 0.89 877851.0 218000.0 1.66 1.8011 0.9577 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L13 compound treatment 744446.0 90200.0 0.66 658295.0 -1570.0 -0.01 0.458 0.6942 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L14 compound treatment 737994.0 83700.0 0.61 745985.0 86100.0 0.65 0.8957 0.9995 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L15 mock treatment 657025.0 2780.0 0.02 770646.0 111000.0 0.84 0.6095 0.724 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L16 mock treatment 750697.0 96500.0 0.71 737971.0 78100.0 0.59 0.9183 0.9963 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L17 compound treatment 492515.0 -162000.0 -1.18 497528.0 -162000.0 -1.23 -1.7084 -0.9998 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L18 compound treatment 702431.0 48200.0 0.35 694098.0 34200.0 0.26 0.4331 0.9888 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L19 compound treatment 675896.0 21700.0 0.16 605103.0 -54800.0 -0.42 -0.1822 -0.4093 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L20 compound treatment 652257.0 -1990.0 -0.01 762988.0 103000.0 0.78 0.5437 0.6939 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L21 compound treatment 668134.0 13900.0 0.1 679132.0 19300.0 0.15 0.1753 0.9841 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L22 compound treatment 697299.0 43100.0 0.31 725465.0 65600.0 0.5 0.575 0.9755 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L23 mock treatment 739072.0 84800.0 0.62 670588.0 10700.0 0.08 0.4962 0.7932 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 L24 mock treatment 628733.0 -25500.0 -0.19 680275.0 20400.0 0.16 -0.0223 -0.0919 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M01 compound treatment 682180.0 27900.0 0.2 622432.0 -37400.0 -0.28 -0.0566 -0.1617 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M02 compound treatment 613768.0 -40500.0 -0.3 664472.0 4610.0 0.03 -0.1846 -0.6192 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M03 compound treatment 678172.0 23900.0 0.17 678961.0 19100.0 0.15 0.2263 0.9957 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M04 compound treatment 782715.0 128000.0 0.94 744415.0 84600.0 0.64 1.1185 0.9828 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M05 compound treatment 793366.0 139000.0 1.02 713483.0 53600.0 0.41 1.0074 0.9193 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M06 compound treatment 678143.0 23900.0 0.17 848336.0 188000.0 1.43 1.136 0.7876 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M07 compound treatment 719299.0 65100.0 0.48 723534.0 63700.0 0.48 0.6784 1.0 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M08 compound treatment 635570.0 -18700.0 -0.14 722651.0 62800.0 0.48 0.2407 0.4851 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M09 mock treatment 671851.0 17600.0 0.13 721483.0 61600.0 0.47 0.422 0.8693 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M10 mock treatment 487754.0 -166000.0 -1.22 693338.0 33500.0 0.25 -0.6811 -0.5476 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M11 compound treatment 734945.0 80700.0 0.59 700155.0 40300.0 0.31 0.6337 0.9533 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M12 compound treatment 745310.0 91100.0 0.67 766656.0 107000.0 0.81 1.0446 0.9952 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M13 mock treatment 736914.0 82700.0 0.6 717589.0 57700.0 0.44 0.7376 0.9876 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M14 mock treatment 730995.0 76700.0 0.56 655163.0 -4700.0 -0.04 0.3716 0.6608 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M15 compound treatment 795396.0 141000.0 1.03 777703.0 118000.0 0.9 1.3629 0.9975 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M16 compound treatment 737892.0 83600.0 0.61 794256.0 134000.0 1.02 1.1545 0.97 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M17 compound treatment 806919.0 153000.0 1.12 718122.0 58300.0 0.44 1.1024 0.9179 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M18 compound treatment 821972.0 168000.0 1.23 784756.0 125000.0 0.95 1.5382 0.9919 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M19 compound treatment 762131.0 108000.0 0.79 741185.0 81300.0 0.62 0.9947 0.9927 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M20 compound treatment 770387.0 116000.0 0.85 713728.0 53900.0 0.41 0.8899 0.9439 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M21 compound treatment 764091.0 110000.0 0.8 701579.0 41700.0 0.32 0.7921 0.9173 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M22 compound treatment 706449.0 52200.0 0.38 703889.0 44000.0 0.33 0.5064 0.9978 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M23 compound treatment 668315.0 14100.0 0.1 615620.0 -44200.0 -0.34 -0.1649 -0.4692 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 M24 compound treatment 616793.0 -37500.0 -0.27 621446.0 -38400.0 -0.29 -0.4001 -0.9995 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N01 compound treatment 689142.0 34900.0 0.26 803891.0 144000.0 1.09 0.9541 0.8492 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N02 compound treatment 757500.0 103000.0 0.76 740325.0 80500.0 0.61 0.9662 0.9945 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N03 compound treatment 737825.0 83600.0 0.61 752480.0 92600.0 0.7 0.9297 0.9975 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N04 compound treatment 771462.0 117000.0 0.86 585076.0 -74800.0 -0.57 0.2044 0.1988 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N05 compound treatment 748128.0 93900.0 0.69 773679.0 114000.0 0.86 1.0969 0.9935 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N06 compound treatment 688896.0 34700.0 0.25 733933.0 74100.0 0.56 0.5771 0.9351 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N07 compound treatment 722454.0 68200.0 0.5 911856.0 252000.0 1.91 1.7063 0.8626 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N08 compound treatment 500052.0 -154000.0 -1.13 840621.0 181000.0 1.37 0.1736 0.0977 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N09 mock treatment 732903.0 78700.0 0.58 791946.0 132000.0 1.0 1.1163 0.9651 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N10 mock treatment 721188.0 66900.0 0.49 758449.0 98600.0 0.75 0.8757 0.9788 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N11 compound treatment 551925.0 -102000.0 -0.75 774881.0 115000.0 0.87 0.0887 0.0771 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N12 compound treatment 648554.0 -5690.0 -0.04 728446.0 68600.0 0.52 0.339 0.6485 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N13 mock treatment 697991.0 43700.0 0.32 774306.0 114000.0 0.87 0.841 0.9078 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N14 mock treatment 660426.0 6180.0 0.05 739593.0 79700.0 0.61 0.4602 0.7578 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N15 compound treatment 747107.0 92900.0 0.68 580926.0 -78900.0 -0.6 0.0562 0.062 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N16 compound treatment 697103.0 42900.0 0.31 806549.0 147000.0 1.11 1.0096 0.8721 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N17 compound treatment 678480.0 24200.0 0.18 727070.0 67200.0 0.51 0.4863 0.8999 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N18 compound treatment 662858.0 8610.0 0.06 747296.0 87400.0 0.66 0.5142 0.7707 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N19 compound treatment 737594.0 83300.0 0.61 753736.0 93900.0 0.71 0.9353 0.9969 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N20 compound treatment 766752.0 113000.0 0.82 885149.0 225000.0 1.71 1.792 0.9437 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N21 compound treatment 733190.0 78900.0 0.58 740978.0 81100.0 0.62 0.8439 0.9995 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N22 compound treatment 705960.0 51700.0 0.38 668208.0 8340.0 0.06 0.3122 0.8143 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N23 compound treatment 740124.0 85900.0 0.63 768420.0 109000.0 0.82 1.0272 0.991 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 N24 compound treatment 646457.0 -7790.0 -0.06 745074.0 85200.0 0.65 0.4174 0.6424 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O01 compound treatment 664186.0 9940.0 0.07 742054.0 82200.0 0.62 0.4929 0.7841 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O02 compound treatment 653020.0 -1230.0 -0.01 782950.0 123000.0 0.94 0.6548 0.7003 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O03 compound treatment 645086.0 -9160.0 -0.07 761483.0 102000.0 0.77 0.4985 0.6433 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O04 compound treatment 722810.0 68600.0 0.5 846860.0 187000.0 1.42 1.359 0.9021 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O05 compound treatment 682367.0 28100.0 0.21 764428.0 105000.0 0.79 0.7071 0.8618 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O06 compound treatment 713841.0 59600.0 0.44 710900.0 51000.0 0.39 0.5823 0.9983 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O07 compound treatment 704188.0 49900.0 0.37 673918.0 14100.0 0.11 0.3337 0.8771 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O08 compound treatment 742830.0 88600.0 0.65 653626.0 -6240.0 -0.05 0.4246 0.6536 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O09 compound treatment 652235.0 -2010.0 -0.01 696280.0 36400.0 0.28 0.1852 0.6686 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O10 compound treatment 751829.0 97600.0 0.71 880832.0 221000.0 1.68 1.6916 0.9274 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O11 mock treatment 812765.0 159000.0 1.16 781789.0 122000.0 0.93 1.4747 0.9938 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O12 mock treatment 749368.0 95100.0 0.7 800174.0 140000.0 1.07 1.2456 0.9786 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O13 compound treatment 716380.0 62100.0 0.45 698112.0 38200.0 0.29 0.5268 0.9767 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O14 compound treatment 799403.0 145000.0 1.06 718566.0 58700.0 0.45 1.066 0.9258 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O15 compound treatment 675174.0 20900.0 0.15 741137.0 81300.0 0.62 0.5448 0.8565 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O16 compound treatment 754144.0 99900.0 0.73 672470.0 12600.0 0.1 0.5843 0.793 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O17 compound treatment 688570.0 34300.0 0.25 700860.0 41000.0 0.31 0.3977 0.9943 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O18 compound treatment 777031.0 123000.0 0.9 726826.0 67000.0 0.51 0.9946 0.9638 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O19 compound treatment 756498.0 102000.0 0.75 735496.0 75600.0 0.57 0.935 0.9915 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O20 compound treatment 749421.0 95200.0 0.7 729650.0 69800.0 0.53 0.867 0.991 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O21 compound treatment 758506.0 104000.0 0.76 776971.0 117000.0 0.89 1.1682 0.9971 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O22 compound treatment 709013.0 54800.0 0.4 662328.0 2460.0 0.02 0.2964 0.7393 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O23 compound treatment 694315.0 40100.0 0.29 626268.0 -33600.0 -0.26 0.0267 0.0688 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 O24 compound treatment 673374.0 19100.0 0.14 628968.0 -30900.0 -0.23 -0.0671 -0.2454 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P01 compound treatment 700684.0 46400.0 0.34 701062.0 41200.0 0.31 0.4614 0.9992 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P02 compound treatment 796987.0 143000.0 1.04 792988.0 133000.0 1.01 1.4532 0.9999 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P03 compound treatment 816380.0 162000.0 1.19 692129.0 32300.0 0.25 1.0117 0.8356 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P04 compound treatment 750683.0 96400.0 0.71 659319.0 -546.0 0.0 0.4958 0.7029 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P05 compound treatment 764946.0 111000.0 0.81 743282.0 83400.0 0.63 1.0205 0.9927 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P06 compound treatment 410316.0 -244000.0 -1.78 454162.0 -206000.0 -1.56 -2.3664 -0.9978 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P07 compound treatment 673659.0 19400.0 0.14 662617.0 2750.0 0.02 0.1152 0.8026 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P08 compound treatment 675298.0 21100.0 0.15 643138.0 -16700.0 -0.13 0.019 0.0952 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P09 compound treatment 709437.0 55200.0 0.4 869042.0 209000.0 1.59 1.409 0.8594 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P10 compound treatment 649301.0 -4940.0 -0.04 670676.0 10800.0 0.08 0.0325 0.3622 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P11 mock treatment 766184.0 112000.0 0.82 789707.0 130000.0 0.99 1.2763 0.9957 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P12 mock treatment 672820.0 18600.0 0.14 645156.0 -14700.0 -0.11 0.017 0.0969 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P13 compound treatment 699224.0 45000.0 0.33 665979.0 6110.0 0.05 0.2654 0.799 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P14 compound treatment 745675.0 91400.0 0.67 795153.0 135000.0 1.03 1.1995 0.9783 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P15 compound treatment 744380.0 90100.0 0.66 718622.0 58800.0 0.45 0.7817 0.982 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P16 compound treatment 716877.0 62600.0 0.46 848712.0 189000.0 1.43 1.3383 0.8887 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P17 compound treatment 495534.0 -159000.0 -1.16 542776.0 -117000.0 -0.89 -1.4497 -0.9914 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P18 compound treatment 885881.0 232000.0 1.69 773685.0 114000.0 0.86 1.8092 0.9513 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P19 compound treatment 661309.0 7060.0 0.05 621930.0 -37900.0 -0.29 -0.1673 -0.5713 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P20 compound treatment 776144.0 122000.0 0.89 702362.0 42500.0 0.32 0.8586 0.9056 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P21 compound treatment 709904.0 55700.0 0.41 878781.0 219000.0 1.66 1.4638 0.8549 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P22 compound treatment 826791.0 173000.0 1.26 813147.0 153000.0 1.16 1.7156 0.9992 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P23 compound treatment 687160.0 32900.0 0.24 653525.0 -6340.0 -0.05 0.1361 0.5546 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2096 P24 compound treatment 729945.0 75700.0 0.55 641839.0 -18000.0 -0.14 0.2946 0.5166 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A01 compound treatment 585268.0 -11000.0 -0.08 636101.0 31500.0 0.24 0.1122 0.4452 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A02 compound treatment 703321.0 107000.0 0.78 524022.0 -80600.0 -0.61 0.1207 0.1214 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A03 compound treatment 651158.0 54900.0 0.4 684399.0 79800.0 0.61 0.7124 0.9801 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A04 compound treatment 594960.0 -1280.0 -0.01 558935.0 -45700.0 -0.35 -0.2521 -0.7259 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A05 compound treatment 514347.0 -81900.0 -0.6 523869.0 -80800.0 -0.61 -0.8574 -0.9999 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A06 compound treatment 618909.0 22700.0 0.17 532181.0 -72500.0 -0.55 -0.272 -0.4732 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A07 compound treatment 686102.0 89900.0 0.66 696992.0 92400.0 0.7 0.9608 0.9995 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A08 compound treatment 559272.0 -37000.0 -0.27 474828.0 -130000.0 -0.99 -0.8885 -0.8689 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A09 compound treatment 596440.0 197.0 0.0 572180.0 -32500.0 -0.25 -0.1733 -0.703 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A10 compound treatment 570226.0 -26000.0 -0.19 370325.0 -234000.0 -1.78 -1.3932 -0.7783 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A11 compound treatment 613565.0 17300.0 0.13 530601.0 -74000.0 -0.56 -0.3081 -0.5345 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A12 compound treatment 585259.0 -11000.0 -0.08 582353.0 -22300.0 -0.17 -0.1765 -0.9419 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A13 mock treatment 585237.0 -11000.0 -0.08 560813.0 -43800.0 -0.33 -0.2923 -0.8535 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A14 mock treatment 581510.0 -14700.0 -0.11 596053.0 -8590.0 -0.07 -0.1223 -0.9711 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A15 compound treatment 408673.0 -188000.0 -1.37 415949.0 -189000.0 -1.43 -1.9835 -0.9998 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A16 compound treatment 612397.0 16200.0 0.12 553657.0 -51000.0 -0.39 -0.1903 -0.47 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A17 compound treatment 584604.0 -11600.0 -0.09 612856.0 8220.0 0.06 -0.0161 -0.1521 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A18 compound treatment 543412.0 -52800.0 -0.39 616466.0 11800.0 0.09 -0.2097 -0.5286 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A19 compound treatment 642060.0 45800.0 0.34 604795.0 155.0 0.0 0.2378 0.7096 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A20 compound treatment 629370.0 33100.0 0.24 596298.0 -8340.0 -0.06 0.1265 0.5051 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A21 compound treatment 552116.0 -44100.0 -0.32 628019.0 23400.0 0.18 -0.1026 -0.2785 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A22 compound treatment 609406.0 13200.0 0.1 711667.0 107000.0 0.81 0.643 0.7853 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A23 compound treatment 409911.0 -186000.0 -1.36 421959.0 -183000.0 -1.39 -1.9449 -1.0 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 A24 compound treatment 574422.0 -21800.0 -0.16 668234.0 63600.0 0.48 0.2288 0.4496 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B01 compound treatment 709928.0 114000.0 0.83 682543.0 77900.0 0.59 1.0064 0.9861 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B02 compound treatment 611544.0 15300.0 0.11 569018.0 -35600.0 -0.27 -0.1122 -0.3832 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B03 compound treatment 551087.0 -45200.0 -0.33 492824.0 -112000.0 -0.85 -0.8342 -0.9153 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B04 compound treatment 572358.0 -23900.0 -0.17 527234.0 -77400.0 -0.59 -0.5393 -0.8792 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B05 compound treatment 649883.0 53600.0 0.39 522927.0 -81700.0 -0.62 -0.1616 -0.22 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B06 compound treatment 616496.0 20300.0 0.15 413617.0 -191000.0 -1.45 -0.9214 -0.6317 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B07 compound treatment 181138.0 -415000.0 -3.04 139565.0 -465000.0 -3.53 -4.6448 -0.9971 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B08 compound treatment 620762.0 24500.0 0.18 604021.0 -619.0 0.0 0.1235 0.6883 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B09 compound treatment 494076.0 -102000.0 -0.75 545687.0 -59000.0 -0.45 -0.845 -0.97 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B10 compound treatment 563621.0 -32600.0 -0.24 615692.0 11100.0 0.08 -0.1093 -0.4323 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B11 compound treatment 548745.0 -47500.0 -0.35 551885.0 -52800.0 -0.4 -0.529 -0.9975 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B12 compound treatment 704617.0 108000.0 0.79 558246.0 -46400.0 -0.35 0.3112 0.3588 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B13 mock treatment 606006.0 9760.0 0.07 543071.0 -61600.0 -0.47 -0.2802 -0.5923 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B14 mock treatment 571349.0 -24900.0 -0.18 546663.0 -58000.0 -0.44 -0.4402 -0.9236 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B15 compound treatment 587753.0 -8490.0 -0.06 577938.0 -26700.0 -0.2 -0.1873 -0.8831 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B16 compound treatment 554188.0 -42100.0 -0.31 549677.0 -55000.0 -0.42 -0.5127 -0.9887 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B17 compound treatment 670891.0 74600.0 0.55 603426.0 -1210.0 -0.01 0.3795 0.6951 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B18 compound treatment 131000.0 -465000.0 -3.4 144420.0 -460000.0 -3.5 -4.878 -0.9999 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B19 compound treatment 599788.0 3550.0 0.03 590459.0 -14200.0 -0.11 -0.0578 -0.522 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B20 compound treatment 623938.0 27700.0 0.2 686310.0 81700.0 0.62 0.5819 0.8916 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B21 compound treatment 696900.0 101000.0 0.74 621898.0 17300.0 0.13 0.6132 0.8201 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B22 compound treatment 643187.0 46900.0 0.34 600273.0 -4370.0 -0.03 0.2193 0.6358 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B23 compound treatment 722887.0 127000.0 0.93 644540.0 39900.0 0.3 0.8692 0.892 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 B24 compound treatment 656673.0 60400.0 0.44 570289.0 -34400.0 -0.26 0.128 0.2493 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C01 compound treatment 533288.0 -63000.0 -0.46 607735.0 3090.0 0.02 -0.3089 -0.6701 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C02 compound treatment 457302.0 -139000.0 -1.02 540999.0 -63600.0 -0.48 -1.0603 -0.9423 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C03 compound treatment 445580.0 -151000.0 -1.1 400072.0 -205000.0 -1.55 -1.878 -0.9858 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C04 compound treatment 469179.0 -127000.0 -0.93 519229.0 -85400.0 -0.65 -1.1159 -0.9846 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C05 compound treatment 550161.0 -46100.0 -0.34 552467.0 -52200.0 -0.4 -0.5186 -0.9967 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C06 compound treatment 518139.0 -78100.0 -0.57 522021.0 -82600.0 -0.63 -0.8477 -0.9989 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C07 compound treatment 530416.0 -65800.0 -0.48 515562.0 -89100.0 -0.68 -0.8189 -0.9861 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C08 compound treatment 579160.0 -17100.0 -0.12 549763.0 -54900.0 -0.42 -0.3831 -0.8803 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C09 compound treatment 503610.0 -92600.0 -0.68 550621.0 -54000.0 -0.41 -0.7692 -0.9712 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C10 compound treatment 596849.0 606.0 0.0 621289.0 16600.0 0.13 0.0926 0.7315 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C11 mock treatment 440608.0 -156000.0 -1.14 593454.0 -11200.0 -0.08 -0.8649 -0.7578 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C12 mock treatment 547748.0 -48500.0 -0.35 512228.0 -92400.0 -0.7 -0.7472 -0.95 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C13 compound treatment 343486.0 -253000.0 -1.85 478413.0 -126000.0 -0.96 -1.9851 -0.9533 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C14 compound treatment 117810.0 -478000.0 -3.5 140075.0 -465000.0 -3.53 -4.9696 -1.0 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C15 mock treatment 707814.0 112000.0 0.82 571305.0 -33300.0 -0.25 0.3979 0.4657 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C16 mock treatment 560983.0 -35300.0 -0.26 510365.0 -94300.0 -0.72 -0.6888 -0.9048 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C17 compound treatment 511390.0 -84900.0 -0.62 694700.0 90100.0 0.68 0.045 0.0487 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C18 compound treatment 506063.0 -90200.0 -0.66 662643.0 58000.0 0.44 -0.1548 -0.1951 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C19 compound treatment 680168.0 83900.0 0.61 566814.0 -37800.0 -0.29 0.2308 0.3406 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C20 compound treatment 157987.0 -438000.0 -3.21 209690.0 -395000.0 -3.0 -4.3879 -0.9995 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C21 compound treatment 375569.0 -221000.0 -1.61 486397.0 -118000.0 -0.9 -1.7763 -0.9617 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C22 compound treatment 686673.0 90400.0 0.66 644069.0 39400.0 0.3 0.6794 0.9359 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C23 compound treatment 631836.0 35600.0 0.26 641677.0 37000.0 0.28 0.383 0.9992 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 C24 compound treatment 683174.0 86900.0 0.64 715570.0 111000.0 0.84 1.0454 0.9903 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D01 compound treatment 555881.0 -40400.0 -0.3 612246.0 7610.0 0.06 -0.1679 -0.5581 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D02 compound treatment 583217.0 -13000.0 -0.1 522162.0 -82500.0 -0.63 -0.5104 -0.8054 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D03 compound treatment 568797.0 -27400.0 -0.2 537478.0 -67200.0 -0.51 -0.5027 -0.9169 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D04 compound treatment 486429.0 -110000.0 -0.8 474935.0 -130000.0 -0.99 -1.2646 -0.9948 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D05 compound treatment 601846.0 5600.0 0.04 577120.0 -27500.0 -0.21 -0.1189 -0.5579 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D06 compound treatment 503991.0 -92300.0 -0.67 473897.0 -131000.0 -0.99 -1.1794 -0.9822 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D07 compound treatment 526717.0 -69500.0 -0.51 488387.0 -116000.0 -0.88 -0.984 -0.9656 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D08 compound treatment 415734.0 -181000.0 -1.32 433592.0 -171000.0 -1.3 -1.8523 -1.0 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D09 compound treatment 521284.0 -75000.0 -0.55 617677.0 13000.0 0.1 -0.3176 -0.5701 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D10 compound treatment 457341.0 -139000.0 -1.02 409804.0 -195000.0 -1.48 -1.7649 -0.9831 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D11 mock treatment 590580.0 -5660.0 -0.04 439336.0 -165000.0 -1.26 -0.9173 -0.73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D12 mock treatment 508752.0 -87500.0 -0.64 570463.0 -34200.0 -0.26 -0.636 -0.9211 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D13 compound treatment 586844.0 -9400.0 -0.07 539722.0 -64900.0 -0.49 -0.3973 -0.7979 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D14 compound treatment 620357.0 24100.0 0.18 599688.0 -4950.0 -0.04 0.0981 0.544 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D15 mock treatment 550358.0 -45900.0 -0.34 513264.0 -91400.0 -0.69 -0.7281 -0.9444 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D16 mock treatment 617305.0 21100.0 0.15 636965.0 32300.0 0.25 0.2826 0.9748 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D17 compound treatment 567657.0 -28600.0 -0.21 616770.0 12100.0 0.09 -0.0827 -0.3618 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D18 compound treatment 585042.0 -11200.0 -0.08 675382.0 70700.0 0.54 0.3221 0.5925 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D19 compound treatment 466429.0 -130000.0 -0.95 528907.0 -75700.0 -0.58 -1.0781 -0.9712 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D20 compound treatment 671461.0 75200.0 0.55 690902.0 86300.0 0.66 0.8523 0.9962 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D21 compound treatment 690688.0 94400.0 0.69 749918.0 145000.0 1.1 1.2688 0.9745 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D22 compound treatment 474471.0 -122000.0 -0.89 457360.0 -147000.0 -1.12 -1.4208 -0.9936 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D23 compound treatment 641252.0 45000.0 0.33 633034.0 28400.0 0.22 0.3853 0.979 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 D24 compound treatment 664076.0 67800.0 0.5 658082.0 53400.0 0.41 0.6379 0.9951 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E01 mock treatment 507584.0 -88700.0 -0.65 551962.0 -52700.0 -0.4 -0.7414 -0.9731 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E02 mock treatment 443751.0 -152000.0 -1.12 524117.0 -80500.0 -0.61 -1.2211 -0.96 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E03 compound treatment 623525.0 27300.0 0.2 615638.0 11000.0 0.08 0.2002 0.9254 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E04 compound treatment 554066.0 -42200.0 -0.31 436354.0 -168000.0 -1.28 -1.1221 -0.8532 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E05 compound treatment 506425.0 -89800.0 -0.66 533789.0 -70900.0 -0.54 -0.8451 -0.9951 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E06 compound treatment 525355.0 -70900.0 -0.52 468738.0 -136000.0 -1.03 -1.0966 -0.9492 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E07 compound treatment 707397.0 111000.0 0.81 581631.0 -23000.0 -0.17 0.4512 0.5427 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E08 compound treatment 544496.0 -51700.0 -0.38 569778.0 -34900.0 -0.26 -0.4549 -0.9848 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E09 mock treatment 516750.0 -79500.0 -0.58 533053.0 -71600.0 -0.54 -0.7956 -0.9994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E10 mock treatment 492295.0 -104000.0 -0.76 566393.0 -38200.0 -0.29 -0.743 -0.913 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E11 compound treatment 578012.0 -18200.0 -0.13 587893.0 -16700.0 -0.13 -0.1842 -0.9997 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E12 compound treatment 121086.0 -475000.0 -3.47 119768.0 -485000.0 -3.68 -5.0617 -0.9996 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E13 compound treatment 547168.0 -49100.0 -0.36 583441.0 -21200.0 -0.16 -0.3676 -0.9346 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E14 compound treatment 670670.0 74400.0 0.54 625424.0 20800.0 0.16 0.4965 0.8761 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E15 compound treatment 489989.0 -106000.0 -0.78 574329.0 -30300.0 -0.23 -0.7123 -0.8789 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E16 compound treatment 131156.0 -465000.0 -3.4 323645.0 -281000.0 -2.13 -3.9145 -0.9748 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E17 mock treatment 640562.0 44300.0 0.32 722077.0 117000.0 0.89 0.86 0.9061 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E18 mock treatment 474350.0 -122000.0 -0.89 574377.0 -30300.0 -0.23 -0.7929 -0.8613 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E19 compound treatment 582931.0 -13300.0 -0.1 637891.0 33300.0 0.25 0.1098 0.4055 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E20 compound treatment 430423.0 -166000.0 -1.21 426974.0 -178000.0 -1.35 -1.8119 -0.9986 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E21 compound treatment 638941.0 42700.0 0.31 660061.0 55400.0 0.42 0.5185 0.9892 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E22 compound treatment 533437.0 -62800.0 -0.46 569511.0 -35100.0 -0.27 -0.5135 -0.9666 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E23 compound treatment 566658.0 -29600.0 -0.22 568342.0 -36300.0 -0.28 -0.348 -0.9928 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 E24 compound treatment 474334.0 -122000.0 -0.89 537399.0 -67200.0 -0.51 -0.9916 -0.9651 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F01 mock treatment 547189.0 -49100.0 -0.36 509227.0 -95400.0 -0.72 -0.7662 -0.9474 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F02 mock treatment 479571.0 -117000.0 -0.85 565720.0 -38900.0 -0.3 -0.8124 -0.8997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F03 compound treatment 499878.0 -96400.0 -0.7 480054.0 -125000.0 -0.95 -1.1676 -0.9895 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F04 compound treatment 668018.0 71800.0 0.52 531360.0 -73300.0 -0.56 -0.0225 -0.0294 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F05 compound treatment 600670.0 4430.0 0.03 511660.0 -93000.0 -0.71 -0.4766 -0.674 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F06 compound treatment 546855.0 -49400.0 -0.36 540708.0 -63900.0 -0.49 -0.5988 -0.9894 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F07 compound treatment 413929.0 -182000.0 -1.33 448446.0 -156000.0 -1.19 -1.7818 -0.9983 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F08 compound treatment 511883.0 -84400.0 -0.62 632434.0 27800.0 0.21 -0.2869 -0.44 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F09 mock treatment 475844.0 -120000.0 -0.88 528613.0 -76000.0 -0.58 -1.031 -0.9791 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F10 mock treatment 490836.0 -105000.0 -0.77 523980.0 -80700.0 -0.61 -0.9784 -0.9935 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F11 compound treatment 470283.0 -126000.0 -0.92 506191.0 -98400.0 -0.75 -1.1802 -0.9947 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F12 compound treatment 149620.0 -447000.0 -3.27 145655.0 -459000.0 -3.49 -4.7751 -0.9995 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F13 compound treatment 525521.0 -70700.0 -0.52 571552.0 -33100.0 -0.25 -0.5435 -0.9451 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F14 compound treatment 492247.0 -104000.0 -0.76 589895.0 -14700.0 -0.11 -0.617 -0.8026 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F15 compound treatment 574569.0 -21700.0 -0.16 546369.0 -58300.0 -0.44 -0.4251 -0.9041 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F16 compound treatment 530757.0 -65500.0 -0.48 615268.0 10600.0 0.08 -0.2815 -0.5797 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F17 mock treatment 560882.0 -35400.0 -0.26 648708.0 44100.0 0.33 0.0539 0.1273 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F18 mock treatment 608452.0 12200.0 0.09 654549.0 49900.0 0.38 0.3312 0.8504 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F19 compound treatment 650573.0 54300.0 0.4 676549.0 71900.0 0.55 0.6672 0.9878 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F20 compound treatment 766518.0 170000.0 1.25 691225.0 86600.0 0.66 1.3456 0.9555 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F21 compound treatment 687801.0 91600.0 0.67 591998.0 -12600.0 -0.1 0.4056 0.5995 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F22 compound treatment 730116.0 134000.0 0.98 637977.0 33300.0 0.25 0.8714 0.8617 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F23 compound treatment 127776.0 -468000.0 -3.43 163550.0 -441000.0 -3.35 -4.7919 -0.9999 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 F24 compound treatment 571000.0 -25200.0 -0.18 604248.0 -392.0 0.0 -0.1326 -0.7184 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G01 compound treatment 603488.0 7250.0 0.05 531713.0 -72900.0 -0.55 -0.3543 -0.6366 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G02 compound treatment 430801.0 -165000.0 -1.21 530275.0 -74400.0 -0.56 -1.255 -0.9399 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G03 mock treatment 559236.0 -37000.0 -0.27 528449.0 -76200.0 -0.58 -0.6006 -0.94 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G04 mock treatment 486330.0 -110000.0 -0.8 516349.0 -88300.0 -0.67 -1.0427 -0.996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G05 compound treatment 458603.0 -138000.0 -1.01 470568.0 -134000.0 -1.02 -1.432 -1.0 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G06 compound treatment 598987.0 2740.0 0.02 606819.0 2180.0 0.02 0.0259 0.9954 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G07 compound treatment 255499.0 -341000.0 -2.49 278313.0 -326000.0 -2.48 -3.515 -1.0 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G08 compound treatment 558061.0 -38200.0 -0.28 564905.0 -39700.0 -0.3 -0.4109 -0.9992 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G09 compound treatment 389536.0 -207000.0 -1.51 547837.0 -56800.0 -0.43 -1.374 -0.874 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G10 compound treatment 562828.0 -33400.0 -0.24 679303.0 74700.0 0.57 0.2283 0.3696 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G11 compound treatment 512249.0 -84000.0 -0.61 503735.0 -101000.0 -0.77 -0.9764 -0.994 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G12 compound treatment 602700.0 6460.0 0.05 606607.0 1970.0 0.01 0.044 0.8875 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G13 compound treatment 589777.0 -6470.0 -0.05 614043.0 9400.0 0.07 0.0171 0.1993 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G14 compound treatment 485685.0 -111000.0 -0.81 540639.0 -64000.0 -0.49 -0.9155 -0.9704 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G15 compound treatment 637955.0 41700.0 0.31 653319.0 48700.0 0.37 0.4772 0.9954 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G16 compound treatment 645891.0 49600.0 0.36 648202.0 43600.0 0.33 0.4907 0.9989 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G17 compound treatment 577551.0 -18700.0 -0.14 766935.0 162000.0 1.23 0.7751 0.6249 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G18 compound treatment 673184.0 76900.0 0.56 618592.0 14000.0 0.11 0.4728 0.8258 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G19 mock treatment 774516.0 178000.0 1.3 708185.0 104000.0 0.79 1.4781 0.9707 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G20 mock treatment 544508.0 -51700.0 -0.38 722064.0 117000.0 0.89 0.3632 0.3749 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G21 compound treatment 738603.0 142000.0 1.04 721831.0 117000.0 0.89 1.3657 0.997 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G22 compound treatment 614629.0 18400.0 0.13 591570.0 -13100.0 -0.1 0.0249 0.1488 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G23 compound treatment 627292.0 31000.0 0.23 567395.0 -37200.0 -0.28 -0.0395 -0.1089 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 G24 compound treatment 490908.0 -105000.0 -0.77 379260.0 -225000.0 -1.71 -1.7554 -0.935 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H01 compound treatment 539028.0 -57200.0 -0.42 539431.0 -65200.0 -0.5 -0.6462 -0.9965 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H02 compound treatment 541000.0 -55200.0 -0.4 643777.0 39100.0 0.3 -0.0754 -0.1504 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H03 mock treatment 474073.0 -122000.0 -0.89 497861.0 -107000.0 -0.81 -1.2053 -0.9988 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H04 mock treatment 513525.0 -82700.0 -0.6 463553.0 -141000.0 -1.07 -1.1856 -0.9634 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H05 compound treatment 401051.0 -195000.0 -1.43 426560.0 -178000.0 -1.35 -1.966 -0.9996 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H06 compound treatment 478964.0 -117000.0 -0.86 625843.0 21200.0 0.16 -0.4926 -0.5644 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H07 compound treatment 467932.0 -128000.0 -0.94 552300.0 -52300.0 -0.4 -0.9447 -0.927 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H08 compound treatment 547115.0 -49100.0 -0.36 537365.0 -67300.0 -0.51 -0.6154 -0.9851 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H09 compound treatment 118433.0 -478000.0 -3.49 118104.0 -487000.0 -3.7 -5.0844 -0.9996 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H10 compound treatment 496710.0 -99500.0 -0.73 642726.0 38100.0 0.29 -0.3101 -0.3959 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H11 compound treatment 534904.0 -61300.0 -0.45 639927.0 35300.0 0.27 -0.1276 -0.2443 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H12 compound treatment 517881.0 -78400.0 -0.57 631451.0 26800.0 0.2 -0.2612 -0.4295 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H13 compound treatment 564435.0 -31800.0 -0.23 636412.0 31800.0 0.24 0.0062 0.0185 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H14 compound treatment 626816.0 30600.0 0.22 626961.0 22300.0 0.17 0.278 0.9907 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H15 compound treatment 598239.0 2000.0 0.01 745466.0 141000.0 1.07 0.7668 0.7167 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H16 compound treatment 573582.0 -22700.0 -0.17 586937.0 -17700.0 -0.13 -0.2123 -0.9946 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H17 compound treatment 578024.0 -18200.0 -0.13 735991.0 131000.0 1.0 0.6114 0.6073 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H18 compound treatment 510631.0 -85600.0 -0.63 619653.0 15000.0 0.11 -0.3621 -0.5689 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H19 mock treatment 486724.0 -110000.0 -0.8 594948.0 -9690.0 -0.07 -0.6184 -0.7689 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H20 mock treatment 728981.0 133000.0 0.97 645887.0 41200.0 0.31 0.908 0.8901 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H21 compound treatment 688066.0 91800.0 0.67 641770.0 37100.0 0.28 0.6743 0.9258 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H22 compound treatment 625839.0 29600.0 0.22 726243.0 122000.0 0.92 0.8063 0.8498 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H23 compound treatment 681820.0 85600.0 0.63 656373.0 51700.0 0.39 0.7204 0.9749 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 H24 compound treatment 565413.0 -30800.0 -0.23 583775.0 -20900.0 -0.16 -0.2715 -0.9851 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I01 compound treatment 589674.0 -6570.0 -0.05 588386.0 -16300.0 -0.12 -0.1213 -0.9154 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I02 compound treatment 547720.0 -48500.0 -0.35 566095.0 -38500.0 -0.29 -0.458 -0.9954 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I03 compound treatment 705682.0 109000.0 0.8 675978.0 71300.0 0.54 0.9491 0.982 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I04 compound treatment 598190.0 1950.0 0.01 579374.0 -25300.0 -0.19 -0.1257 -0.6528 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I05 mock treatment 515694.0 -80500.0 -0.59 529129.0 -75500.0 -0.57 -0.8222 -0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I06 mock treatment 533519.0 -62700.0 -0.46 555837.0 -48800.0 -0.37 -0.5865 -0.9944 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I07 compound treatment 570782.0 -25500.0 -0.19 581231.0 -23400.0 -0.18 -0.2574 -0.9997 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I08 compound treatment 570043.0 -26200.0 -0.19 620261.0 15600.0 0.12 -0.0516 -0.2288 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I09 compound treatment 597495.0 1250.0 0.01 550524.0 -54100.0 -0.41 -0.2842 -0.6912 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I10 compound treatment 529249.0 -67000.0 -0.49 557454.0 -47200.0 -0.36 -0.5999 -0.9882 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I11 compound treatment 654357.0 58100.0 0.42 633629.0 29000.0 0.22 0.4562 0.9531 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I12 compound treatment 225493.0 -371000.0 -2.71 239094.0 -366000.0 -2.78 -3.8808 -0.9999 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I13 compound treatment 600831.0 4590.0 0.03 586226.0 -18400.0 -0.14 -0.0752 -0.5227 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I14 compound treatment 658340.0 62100.0 0.45 659290.0 54600.0 0.42 0.6147 0.999 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I15 compound treatment 649729.0 53500.0 0.39 557904.0 -46700.0 -0.36 0.0255 0.0483 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I16 compound treatment 625071.0 28800.0 0.21 631491.0 26900.0 0.2 0.2933 0.9999 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I17 compound treatment 620895.0 24700.0 0.18 661396.0 56800.0 0.43 0.4324 0.9252 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I18 compound treatment 704278.0 108000.0 0.79 662917.0 58300.0 0.44 0.8717 0.9625 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I19 compound treatment 620133.0 23900.0 0.17 756502.0 152000.0 1.15 0.9393 0.805 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I20 compound treatment 670427.0 74200.0 0.54 617546.0 12900.0 0.1 0.4529 0.8216 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I21 mock treatment 740828.0 145000.0 1.06 794255.0 190000.0 1.44 1.7662 0.9884 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I22 mock treatment 685869.0 89600.0 0.66 679236.0 74600.0 0.57 0.8642 0.9974 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I23 compound treatment 675659.0 79400.0 0.58 643190.0 38500.0 0.29 0.6178 0.9497 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 I24 compound treatment 402880.0 -193000.0 -1.41 368494.0 -236000.0 -1.79 -2.2684 -0.9931 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J01 compound treatment 597851.0 1610.0 0.01 627910.0 23300.0 0.18 0.1333 0.7525 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J02 compound treatment 557247.0 -39000.0 -0.29 555410.0 -49200.0 -0.37 -0.4661 -0.991 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J03 compound treatment 527135.0 -69100.0 -0.51 639531.0 34900.0 0.27 -0.1699 -0.2978 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J04 compound treatment 582243.0 -14000.0 -0.1 690868.0 86200.0 0.66 0.3908 0.5894 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J05 mock treatment 507462.0 -88800.0 -0.65 568179.0 -36500.0 -0.28 -0.655 -0.9279 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J06 mock treatment 629214.0 33000.0 0.24 553905.0 -50700.0 -0.39 -0.102 -0.2244 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J07 compound treatment 808894.0 213000.0 1.56 677147.0 72500.0 0.55 1.4891 0.9026 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J08 compound treatment 521411.0 -74800.0 -0.55 695883.0 91200.0 0.69 0.1032 0.1168 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J09 compound treatment 459296.0 -137000.0 -1.0 474407.0 -130000.0 -0.99 -1.4077 -1.0 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J10 compound treatment 601014.0 4770.0 0.03 712226.0 108000.0 0.82 0.6026 0.7366 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J11 compound treatment 556855.0 -39400.0 -0.29 644243.0 39600.0 0.3 0.0091 0.0217 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J12 compound treatment 438756.0 -157000.0 -1.15 437792.0 -167000.0 -1.27 -1.7107 -0.9989 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J13 compound treatment 584541.0 -11700.0 -0.09 580999.0 -23600.0 -0.18 -0.1875 -0.9425 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J14 compound treatment 658566.0 62300.0 0.46 547722.0 -56900.0 -0.43 0.0165 0.0263 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J15 compound treatment 596571.0 328.0 0.0 744836.0 140000.0 1.07 0.7548 0.7087 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J16 compound treatment 447374.0 -149000.0 -1.09 465100.0 -140000.0 -1.06 -1.5194 -0.9999 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J17 compound treatment 244600.0 -352000.0 -2.57 159379.0 -445000.0 -3.38 -4.2102 -0.9909 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J18 compound treatment 665841.0 69600.0 0.51 801735.0 197000.0 1.5 1.4186 0.8971 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J19 compound treatment 705799.0 110000.0 0.8 562052.0 -42600.0 -0.32 0.3378 0.3909 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J20 compound treatment 620999.0 24800.0 0.18 596132.0 -8510.0 -0.06 0.0823 0.4282 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J21 mock treatment 746183.0 150000.0 1.1 638832.0 34200.0 0.26 0.959 0.8511 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J22 mock treatment 536693.0 -59500.0 -0.44 763824.0 159000.0 1.21 0.5472 0.4257 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J23 compound treatment 748151.0 152000.0 1.11 702262.0 97600.0 0.74 1.3099 0.9807 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 J24 compound treatment 617294.0 21100.0 0.15 643096.0 38500.0 0.29 0.3154 0.9552 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K01 compound treatment 553138.0 -43100.0 -0.32 648551.0 43900.0 0.33 0.013 0.0283 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K02 compound treatment 567504.0 -28700.0 -0.21 636379.0 31700.0 0.24 0.0219 0.0684 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K03 compound treatment 592653.0 -3590.0 -0.03 757665.0 153000.0 1.16 0.8034 0.691 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K04 compound treatment 708077.0 112000.0 0.82 682586.0 77900.0 0.59 0.997 0.9874 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K05 compound treatment 558981.0 -37300.0 -0.27 517780.0 -86900.0 -0.66 -0.6593 -0.9235 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K06 compound treatment 637844.0 41600.0 0.3 623911.0 19300.0 0.15 0.3186 0.9438 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K07 mock treatment 615849.0 19600.0 0.14 728199.0 124000.0 0.94 0.7651 0.8058 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K08 mock treatment 568558.0 -27700.0 -0.2 710221.0 106000.0 0.8 0.424 0.5125 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K09 compound treatment 686638.0 90400.0 0.66 651016.0 46400.0 0.35 0.7166 0.9566 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K10 compound treatment 120378.0 -476000.0 -3.48 139203.0 -465000.0 -3.54 -4.961 -1.0 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K11 compound treatment 744320.0 148000.0 1.08 693775.0 89100.0 0.68 1.2445 0.9744 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K12 compound treatment 632693.0 36500.0 0.27 649587.0 44900.0 0.34 0.4299 0.9925 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K13 compound treatment 644903.0 48700.0 0.36 622809.0 18200.0 0.14 0.3492 0.915 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K14 compound treatment 681281.0 85000.0 0.62 672199.0 67600.0 0.51 0.8027 0.9954 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K15 mock treatment 710732.0 114000.0 0.84 580181.0 -24500.0 -0.19 0.4607 0.5371 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K16 mock treatment 591473.0 -4770.0 -0.03 604719.0 79.0 0.0 -0.0242 -0.6948 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K17 compound treatment 683367.0 87100.0 0.64 670495.0 65900.0 0.5 0.8043 0.9928 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K18 compound treatment 659094.0 62900.0 0.46 781291.0 177000.0 1.34 1.2739 0.8981 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K19 compound treatment 685157.0 88900.0 0.65 723665.0 119000.0 0.9 1.0992 0.9869 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K20 compound treatment 670665.0 74400.0 0.54 688185.0 83500.0 0.63 0.8336 0.9971 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K21 compound treatment 746020.0 150000.0 1.1 722164.0 118000.0 0.89 1.4058 0.9949 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K22 compound treatment 657392.0 61100.0 0.45 676524.0 71900.0 0.55 0.7024 0.9951 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K23 mock treatment 632562.0 36300.0 0.27 645540.0 40900.0 0.31 0.4075 0.997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 K24 mock treatment 628803.0 32600.0 0.24 608057.0 3420.0 0.03 0.1867 0.7796 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L01 compound treatment 626791.0 30500.0 0.22 614496.0 9860.0 0.07 0.2109 0.8952 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L02 compound treatment 585485.0 -10800.0 -0.08 649466.0 44800.0 0.34 0.1852 0.5298 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L03 compound treatment 111973.0 -484000.0 -3.54 107606.0 -497000.0 -3.78 -5.1742 -0.9995 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L04 compound treatment 577870.0 -18400.0 -0.13 651221.0 46600.0 0.35 0.1552 0.4101 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L05 compound treatment 662571.0 66300.0 0.49 616003.0 11400.0 0.09 0.404 0.8201 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L06 compound treatment 632705.0 36500.0 0.27 631285.0 26600.0 0.2 0.3317 0.9908 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L07 mock treatment 530044.0 -66200.0 -0.48 611789.0 7150.0 0.05 -0.3039 -0.6239 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L08 mock treatment 632976.0 36700.0 0.27 623644.0 19000.0 0.14 0.292 0.9576 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L09 compound treatment 607398.0 11200.0 0.08 541050.0 -63600.0 -0.48 -0.2839 -0.5795 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L10 compound treatment 758610.0 162000.0 1.19 667592.0 63000.0 0.48 1.1778 0.9201 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L11 compound treatment 762880.0 167000.0 1.22 601790.0 -2850.0 -0.02 0.8464 0.6944 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L12 compound treatment 624215.0 28000.0 0.2 587815.0 -16800.0 -0.13 0.0543 0.225 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L13 compound treatment 474628.0 -122000.0 -0.89 444817.0 -160000.0 -1.21 -1.4874 -0.9883 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L14 compound treatment 613520.0 17300.0 0.13 466380.0 -138000.0 -1.05 -0.6534 -0.6176 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L15 mock treatment 744907.0 149000.0 1.09 721197.0 117000.0 0.89 1.3949 0.9948 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L16 mock treatment 694749.0 98500.0 0.72 655454.0 50800.0 0.39 0.7824 0.9572 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L17 compound treatment 695864.0 99600.0 0.73 554727.0 -49900.0 -0.38 0.247 0.3008 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L18 compound treatment 603806.0 7560.0 0.06 657881.0 53200.0 0.4 0.3251 0.7964 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L19 compound treatment 734535.0 138000.0 1.01 595272.0 -9370.0 -0.07 0.6648 0.6557 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L20 compound treatment 725154.0 129000.0 0.94 741242.0 137000.0 1.04 1.4004 0.9989 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L21 compound treatment 630269.0 34000.0 0.25 734537.0 130000.0 0.99 0.8737 0.8585 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L22 compound treatment 641647.0 45400.0 0.33 710278.0 106000.0 0.8 0.8023 0.9237 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L23 mock treatment 652200.0 56000.0 0.41 558999.0 -45600.0 -0.35 0.0442 0.0824 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 L24 mock treatment 617523.0 21300.0 0.16 640926.0 36300.0 0.28 0.305 0.9634 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M01 compound treatment 633315.0 37100.0 0.27 753644.0 149000.0 1.13 0.9921 0.8524 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M02 compound treatment 651912.0 55700.0 0.41 726034.0 121000.0 0.92 0.94 0.9324 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M03 compound treatment 614741.0 18500.0 0.14 717612.0 113000.0 0.86 0.7025 0.8086 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M04 compound treatment 706874.0 111000.0 0.81 698987.0 94300.0 0.72 1.0789 0.9982 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M05 compound treatment 559653.0 -36600.0 -0.27 662519.0 57900.0 0.44 0.1217 0.2364 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M06 compound treatment 592026.0 -4220.0 -0.03 593636.0 -11000.0 -0.08 -0.0809 -0.9081 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M07 compound treatment 153522.0 -443000.0 -3.24 192220.0 -412000.0 -3.13 -4.5048 -0.9999 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M08 compound treatment 537776.0 -58500.0 -0.43 538113.0 -66500.0 -0.51 -0.6597 -0.9965 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M09 mock treatment 629193.0 33000.0 0.24 683924.0 79300.0 0.6 0.5963 0.9192 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M10 mock treatment 702026.0 106000.0 0.77 635416.0 30800.0 0.23 0.7123 0.8814 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M11 compound treatment 524641.0 -71600.0 -0.52 548114.0 -56500.0 -0.43 -0.6739 -0.9951 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M12 compound treatment 232138.0 -364000.0 -2.66 221461.0 -383000.0 -2.91 -3.9412 -0.999 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M13 mock treatment 614367.0 18100.0 0.13 715190.0 111000.0 0.84 0.6876 0.8087 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M14 mock treatment 664132.0 67900.0 0.5 679195.0 74600.0 0.57 0.7516 0.9978 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M15 compound treatment 193425.0 -403000.0 -2.95 267934.0 -337000.0 -2.56 -3.8917 -0.9975 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M16 compound treatment 717279.0 121000.0 0.89 690605.0 86000.0 0.65 1.0877 0.9888 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M17 compound treatment 703351.0 107000.0 0.78 552683.0 -52000.0 -0.39 0.2748 0.3133 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M18 compound treatment 644538.0 48300.0 0.35 691461.0 86800.0 0.66 0.7161 0.9572 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M19 compound treatment 205165.0 -391000.0 -2.86 193519.0 -411000.0 -3.12 -4.2308 -0.999 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M20 compound treatment 641690.0 45400.0 0.33 779530.0 175000.0 1.33 1.1745 0.8576 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M21 compound treatment 713761.0 118000.0 0.86 748482.0 144000.0 1.09 1.3804 0.9929 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M22 compound treatment 605126.0 8880.0 0.06 728471.0 124000.0 0.94 0.7111 0.7541 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M23 compound treatment 731428.0 135000.0 0.99 727496.0 123000.0 0.93 1.359 0.9996 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 M24 compound treatment 707635.0 111000.0 0.81 712264.0 108000.0 0.82 1.1542 1.0 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N01 compound treatment 581945.0 -14300.0 -0.1 594263.0 -10400.0 -0.08 -0.1297 -0.9903 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N02 compound treatment 627005.0 30800.0 0.22 626705.0 22100.0 0.17 0.2776 0.9895 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N03 compound treatment 556854.0 -39400.0 -0.29 738358.0 134000.0 1.02 0.5146 0.4874 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N04 compound treatment 616153.0 19900.0 0.15 663410.0 58800.0 0.45 0.4187 0.8915 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N05 compound treatment 602283.0 6040.0 0.04 686104.0 81500.0 0.62 0.4688 0.7557 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N06 compound treatment 605185.0 8940.0 0.07 756735.0 152000.0 1.16 0.8633 0.7459 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N07 compound treatment 544857.0 -51400.0 -0.38 683263.0 78600.0 0.6 0.1566 0.2219 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N08 compound treatment 698472.0 102000.0 0.75 643960.0 39300.0 0.3 0.7399 0.919 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N09 mock treatment 702680.0 106000.0 0.78 684505.0 79900.0 0.61 0.9794 0.9924 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N10 mock treatment 725692.0 129000.0 0.95 584523.0 -20100.0 -0.15 0.5613 0.5854 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N11 compound treatment 716262.0 120000.0 0.88 767050.0 162000.0 1.23 1.4931 0.9861 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N12 compound treatment 799049.0 203000.0 1.48 653233.0 48600.0 0.37 1.3098 0.857 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N13 mock treatment 611018.0 14800.0 0.11 667770.0 63100.0 0.48 0.4155 0.8452 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N14 mock treatment 666172.0 69900.0 0.51 595060.0 -9580.0 -0.07 0.3102 0.6004 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N15 compound treatment 644678.0 48400.0 0.35 809431.0 205000.0 1.56 1.3505 0.8464 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N16 compound treatment 615445.0 19200.0 0.14 731021.0 126000.0 0.96 0.7782 0.802 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N17 compound treatment 747076.0 151000.0 1.1 762902.0 158000.0 1.2 1.6301 0.9991 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N18 compound treatment 849545.0 253000.0 1.85 841682.0 237000.0 1.8 2.5832 0.9999 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N19 compound treatment 419028.0 -177000.0 -1.3 429041.0 -176000.0 -1.33 -1.8597 -0.9999 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N20 compound treatment 803616.0 207000.0 1.52 770600.0 166000.0 1.26 1.9639 0.9958 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N21 compound treatment 769928.0 174000.0 1.27 719164.0 115000.0 0.87 1.5133 0.983 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N22 compound treatment 821818.0 226000.0 1.65 807555.0 203000.0 1.54 2.2565 0.9994 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N23 compound treatment 734956.0 139000.0 1.01 765846.0 161000.0 1.22 1.5833 0.9956 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 N24 compound treatment 745992.0 150000.0 1.1 865038.0 260000.0 1.98 2.1732 0.9611 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O01 compound treatment 706854.0 111000.0 0.81 638181.0 33500.0 0.25 0.7522 0.8869 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O02 compound treatment 603078.0 6840.0 0.05 680044.0 75400.0 0.57 0.4404 0.7659 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O03 compound treatment 668503.0 72300.0 0.53 761635.0 157000.0 1.19 1.217 0.9329 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O04 compound treatment 674702.0 78500.0 0.57 599482.0 -5160.0 -0.04 0.378 0.6573 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O05 compound treatment 678444.0 82200.0 0.6 754374.0 150000.0 1.14 1.2294 0.9556 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O06 compound treatment 624859.0 28600.0 0.21 731743.0 127000.0 0.97 0.8307 0.8408 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O07 compound treatment 775897.0 180000.0 1.31 743554.0 139000.0 1.06 1.6752 0.9941 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O08 compound treatment 684814.0 88600.0 0.65 650527.0 45900.0 0.35 0.7045 0.9578 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O09 compound treatment 746213.0 150000.0 1.1 627784.0 23100.0 0.18 0.8998 0.8101 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O10 compound treatment 648624.0 52400.0 0.38 772344.0 168000.0 1.27 1.1717 0.8808 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O11 mock treatment 739931.0 144000.0 1.05 731358.0 127000.0 0.96 1.4237 0.999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O12 mock treatment 612542.0 16300.0 0.12 730941.0 126000.0 0.96 0.7627 0.7889 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O13 compound treatment 790350.0 194000.0 1.42 805278.0 201000.0 1.52 2.0815 0.9994 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O14 compound treatment 683024.0 86800.0 0.63 684251.0 79600.0 0.6 0.8764 0.9997 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O15 compound treatment 740397.0 144000.0 1.05 659471.0 54800.0 0.42 1.04 0.9175 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O16 compound treatment 626185.0 29900.0 0.22 625978.0 21300.0 0.16 0.2695 0.989 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O17 compound treatment 731577.0 135000.0 0.99 624778.0 20100.0 0.15 0.808 0.8068 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O18 compound treatment 710891.0 115000.0 0.84 765600.0 161000.0 1.22 1.4575 0.9831 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O19 compound treatment 688655.0 92400.0 0.68 681516.0 76900.0 0.58 0.8908 0.9974 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O20 compound treatment 677613.0 81400.0 0.6 651514.0 46900.0 0.36 0.6726 0.9699 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O21 compound treatment 738364.0 142000.0 1.04 737626.0 133000.0 1.01 1.4493 0.9999 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O22 compound treatment 759589.0 163000.0 1.19 753314.0 149000.0 1.13 1.6433 0.9996 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O23 compound treatment 193003.0 -403000.0 -2.95 120329.0 -484000.0 -3.68 -4.6868 -0.994 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 O24 compound treatment 685905.0 89700.0 0.66 754308.0 150000.0 1.14 1.2676 0.9658 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P01 compound treatment 654303.0 58100.0 0.42 645824.0 41200.0 0.31 0.5215 0.9887 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P02 compound treatment 703865.0 108000.0 0.79 727775.0 123000.0 0.94 1.218 0.9963 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P03 compound treatment 640328.0 44100.0 0.32 746031.0 141000.0 1.07 0.9875 0.8805 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P04 compound treatment 741923.0 146000.0 1.07 792176.0 188000.0 1.42 1.7607 0.9897 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P05 compound treatment 117161.0 -479000.0 -3.5 105659.0 -499000.0 -3.79 -5.1578 -0.9992 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P06 compound treatment 651507.0 55300.0 0.4 639680.0 35000.0 0.27 0.474 0.9795 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P07 compound treatment 721844.0 126000.0 0.92 596541.0 -8100.0 -0.06 0.606 0.6583 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P08 compound treatment 589580.0 -6660.0 -0.05 592538.0 -12100.0 -0.09 -0.0995 -0.9559 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P09 compound treatment 689409.0 93200.0 0.68 677084.0 72400.0 0.55 0.8709 0.9944 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P10 compound treatment 696593.0 100000.0 0.73 763378.0 159000.0 1.21 1.3716 0.9716 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P11 mock treatment 705482.0 109000.0 0.8 611482.0 6840.0 0.05 0.6016 0.7515 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P12 mock treatment 797235.0 201000.0 1.47 621038.0 16400.0 0.12 1.1274 0.7643 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P13 compound treatment 843753.0 248000.0 1.81 735795.0 131000.0 1.0 1.9844 0.9604 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P14 compound treatment 766411.0 170000.0 1.24 722167.0 118000.0 0.89 1.5113 0.9867 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P15 compound treatment 679444.0 83200.0 0.61 641586.0 36900.0 0.28 0.6287 0.9383 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P16 compound treatment 674408.0 78200.0 0.57 637557.0 32900.0 0.25 0.581 0.9312 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P17 compound treatment 747126.0 151000.0 1.1 732330.0 128000.0 0.97 1.4662 0.9979 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P18 compound treatment 588341.0 -7900.0 -0.06 606527.0 1890.0 0.01 -0.0307 -0.5161 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P19 compound treatment 756154.0 160000.0 1.17 756171.0 152000.0 1.15 1.6409 1.0 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P20 compound treatment 696654.0 100000.0 0.73 787120.0 182000.0 1.39 1.4995 0.9558 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P21 compound treatment 655861.0 59600.0 0.44 682786.0 78100.0 0.59 0.7281 0.9885 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P22 compound treatment 792115.0 196000.0 1.43 677563.0 72900.0 0.55 1.4046 0.9146 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P23 compound treatment 689378.0 93100.0 0.68 737703.0 133000.0 1.01 1.1964 0.9815 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2097 P24 compound treatment 800379.0 204000.0 1.49 756518.0 152000.0 1.15 1.8715 0.9919 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A01 compound treatment 502696.0 -56600.0 -0.41 580779.0 -77500.0 -0.59 -0.7092 -0.9851 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A02 compound treatment 555373.0 -3930.0 -0.03 581138.0 -77200.0 -0.59 -0.4349 -0.7409 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A03 compound treatment 567031.0 7730.0 0.06 580530.0 -77800.0 -0.59 -0.3779 -0.6365 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A04 compound treatment 499714.0 -59600.0 -0.44 583617.0 -74700.0 -0.57 -0.7094 -0.9915 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A05 compound treatment 317989.0 -241000.0 -1.76 360454.0 -298000.0 -2.26 -2.8479 -0.9924 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A06 compound treatment 446029.0 -113000.0 -0.83 563448.0 -94900.0 -0.72 -1.0953 -0.9976 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A07 compound treatment 592808.0 33500.0 0.25 608802.0 -49500.0 -0.38 -0.0927 -0.2065 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A08 compound treatment 536844.0 -22500.0 -0.16 533074.0 -125000.0 -0.95 -0.7889 -0.8171 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A09 compound treatment 483774.0 -75500.0 -0.55 549447.0 -109000.0 -0.83 -0.9754 -0.9807 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A10 compound treatment 522951.0 -36300.0 -0.27 578307.0 -80000.0 -0.61 -0.6177 -0.9312 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A11 compound treatment 434125.0 -125000.0 -0.92 309319.0 -349000.0 -2.65 -2.522 -0.8992 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A12 compound treatment 576798.0 17500.0 0.13 649448.0 -8870.0 -0.07 0.0429 0.2964 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A13 mock treatment 569994.0 10700.0 0.08 655444.0 -2870.0 -0.02 0.0399 0.4912 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A14 mock treatment 554814.0 -4490.0 -0.03 597509.0 -60800.0 -0.46 -0.3498 -0.7554 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A15 compound treatment 622287.0 63000.0 0.46 667393.0 9080.0 0.07 0.3745 0.804 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A16 compound treatment 630643.0 71300.0 0.52 606436.0 -51900.0 -0.39 0.0902 0.138 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A17 compound treatment 616204.0 56900.0 0.42 658273.0 -41.7 0.0 0.294 0.7066 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A18 compound treatment 588793.0 29500.0 0.22 618188.0 -40100.0 -0.3 -0.063 -0.1688 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A19 compound treatment 478574.0 -80700.0 -0.59 503392.0 -155000.0 -1.18 -1.2496 -0.9491 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A20 compound treatment 507276.0 -52000.0 -0.38 539881.0 -118000.0 -0.9 -0.9052 -0.9267 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A21 compound treatment 357558.0 -202000.0 -1.48 378186.0 -280000.0 -2.13 -2.548 -0.984 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A22 compound treatment 528971.0 -30300.0 -0.22 566114.0 -92200.0 -0.7 -0.6521 -0.8876 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A23 compound treatment 558465.0 -835.0 -0.01 582154.0 -76200.0 -0.58 -0.4134 -0.7145 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 A24 compound treatment 438283.0 -121000.0 -0.89 489717.0 -169000.0 -1.28 -1.5315 -0.9837 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B01 compound treatment 399769.0 -160000.0 -1.17 386438.0 -272000.0 -2.07 -2.2854 -0.9634 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B02 compound treatment 559652.0 352.0 0.0 578907.0 -79400.0 -0.6 -0.4247 -0.7041 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B03 compound treatment 515393.0 -43900.0 -0.32 630747.0 -27600.0 -0.21 -0.3751 -0.9786 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B04 compound treatment 465940.0 -93400.0 -0.68 599934.0 -58400.0 -0.44 -0.7964 -0.9782 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B05 compound treatment 579250.0 20000.0 0.15 615880.0 -42400.0 -0.32 -0.1248 -0.3526 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B06 compound treatment 502106.0 -57200.0 -0.42 591181.0 -67100.0 -0.51 -0.6564 -0.9952 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B07 compound treatment 514890.0 -44400.0 -0.32 647138.0 -11200.0 -0.08 -0.2897 -0.863 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B08 compound treatment 566822.0 7520.0 0.06 623167.0 -35100.0 -0.27 -0.1499 -0.5499 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B09 compound treatment 473189.0 -86100.0 -0.63 624208.0 -34100.0 -0.26 -0.6285 -0.923 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B10 compound treatment 560419.0 1120.0 0.01 641095.0 -17200.0 -0.13 -0.0867 -0.6616 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B11 compound treatment 445533.0 -114000.0 -0.83 556974.0 -101000.0 -0.77 -1.1327 -0.9992 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B12 compound treatment 466591.0 -92700.0 -0.68 567165.0 -91100.0 -0.69 -0.969 -0.9999 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B13 mock treatment 451259.0 -108000.0 -0.79 587966.0 -70300.0 -0.53 -0.9366 -0.9819 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B14 mock treatment 540202.0 -19100.0 -0.14 702312.0 44000.0 0.33 0.1376 0.3798 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B15 compound treatment 640074.0 80800.0 0.59 634842.0 -23500.0 -0.18 0.2916 0.4726 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B16 compound treatment 532568.0 -26700.0 -0.2 595843.0 -62500.0 -0.47 -0.4738 -0.9231 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B17 compound treatment 642714.0 83400.0 0.61 671768.0 13500.0 0.1 0.5036 0.8142 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B18 compound treatment 617943.0 58600.0 0.43 559482.0 -98800.0 -0.75 -0.2277 -0.2633 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B19 compound treatment 551796.0 -7500.0 -0.05 602233.0 -56100.0 -0.43 -0.3401 -0.7916 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B20 compound treatment 487627.0 -71700.0 -0.52 429355.0 -229000.0 -1.74 -1.6005 -0.8811 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B21 compound treatment 570089.0 10800.0 0.08 626031.0 -32300.0 -0.25 -0.1176 -0.4566 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B22 compound treatment 636114.0 76800.0 0.56 582642.0 -75700.0 -0.57 -0.0093 -0.0115 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B23 compound treatment 509951.0 -49300.0 -0.36 556730.0 -102000.0 -0.77 -0.8009 -0.9401 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 B24 compound treatment 487684.0 -71600.0 -0.52 623132.0 -35200.0 -0.27 -0.5593 -0.9513 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C01 compound treatment 503792.0 -55500.0 -0.41 578757.0 -79600.0 -0.6 -0.7144 -0.9813 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C02 compound treatment 460460.0 -98800.0 -0.72 643297.0 -15000.0 -0.11 -0.5918 -0.8087 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C03 compound treatment 487457.0 -71800.0 -0.53 712076.0 53800.0 0.41 -0.0827 -0.1243 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C04 compound treatment 422448.0 -137000.0 -1.0 529863.0 -128000.0 -0.98 -1.3977 -0.9999 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C05 compound treatment 473483.0 -85800.0 -0.63 594563.0 -63800.0 -0.48 -0.7862 -0.9918 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C06 compound treatment 522423.0 -36900.0 -0.27 553584.0 -105000.0 -0.8 -0.7533 -0.8967 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C07 compound treatment 440892.0 -118000.0 -0.87 623647.0 -34700.0 -0.26 -0.7985 -0.8823 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C08 compound treatment 437257.0 -122000.0 -0.89 577240.0 -81100.0 -0.62 -1.0666 -0.9836 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C09 compound treatment 307003.0 -252000.0 -1.85 312960.0 -345000.0 -2.62 -3.1598 -0.9852 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C10 compound treatment 296473.0 -263000.0 -1.92 236371.0 -422000.0 -3.21 -3.6257 -0.9701 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C11 mock treatment 613113.0 53800.0 0.39 573606.0 -84700.0 -0.64 -0.1768 -0.2343 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C12 mock treatment 490767.0 -68500.0 -0.5 583697.0 -74600.0 -0.57 -0.7552 -0.9981 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C13 compound treatment 339381.0 -220000.0 -1.61 311522.0 -347000.0 -2.63 -3.0001 -0.972 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C14 compound treatment 505768.0 -53500.0 -0.39 612033.0 -46300.0 -0.35 -0.5254 -0.9986 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C15 mock treatment 538451.0 -20800.0 -0.15 655629.0 -2690.0 -0.02 -0.1222 -0.7946 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C16 mock treatment 558294.0 -1010.0 -0.01 675454.0 17100.0 0.13 0.0869 0.6661 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C17 compound treatment 608283.0 49000.0 0.36 577397.0 -80900.0 -0.61 -0.1814 -0.2549 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C18 compound treatment 594953.0 35700.0 0.26 541336.0 -117000.0 -0.89 -0.444 -0.4794 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C19 compound treatment 455666.0 -104000.0 -0.76 518968.0 -139000.0 -1.06 -1.2844 -0.9866 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C20 compound treatment 574962.0 15700.0 0.11 662327.0 4010.0 0.03 0.1025 0.8652 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C21 compound treatment 581516.0 22200.0 0.16 677965.0 19700.0 0.15 0.2204 0.9991 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C22 compound treatment 532417.0 -26900.0 -0.2 582516.0 -75800.0 -0.58 -0.5462 -0.8977 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C23 compound treatment 531065.0 -28200.0 -0.21 620707.0 -37600.0 -0.29 -0.348 -0.9873 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 C24 compound treatment 563443.0 4140.0 0.03 646578.0 -11700.0 -0.09 -0.0416 -0.442 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D01 compound treatment 455511.0 -104000.0 -0.76 575581.0 -82700.0 -0.63 -0.9811 -0.9956 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D02 compound treatment 480463.0 -78800.0 -0.58 612186.0 -46100.0 -0.35 -0.6555 -0.9715 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D03 compound treatment 540997.0 -18300.0 -0.13 585502.0 -72800.0 -0.55 -0.4858 -0.8536 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D04 compound treatment 472011.0 -87300.0 -0.64 641430.0 -16900.0 -0.13 -0.5421 -0.8325 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D05 compound treatment 466919.0 -92400.0 -0.68 633482.0 -24800.0 -0.19 -0.6111 -0.8712 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D06 compound treatment 410645.0 -149000.0 -1.09 565471.0 -92800.0 -0.71 -1.2674 -0.9781 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D07 compound treatment 470919.0 -88400.0 -0.65 515009.0 -143000.0 -1.09 -1.2268 -0.969 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D08 compound treatment 459852.0 -99400.0 -0.73 593675.0 -64600.0 -0.49 -0.8615 -0.9817 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D09 compound treatment 582352.0 23100.0 0.17 694391.0 36100.0 0.27 0.313 0.9728 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D10 compound treatment 490924.0 -68400.0 -0.5 440845.0 -217000.0 -1.65 -1.5218 -0.8816 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D11 mock treatment 506914.0 -52400.0 -0.38 644432.0 -13900.0 -0.11 -0.3455 -0.8694 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D12 mock treatment 458038.0 -101000.0 -0.74 619751.0 -38600.0 -0.29 -0.7308 -0.9176 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D13 compound treatment 451329.0 -108000.0 -0.79 606942.0 -51400.0 -0.39 -0.8343 -0.9472 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D14 compound treatment 539905.0 -19400.0 -0.14 603416.0 -54900.0 -0.42 -0.3952 -0.8971 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D15 mock treatment 569133.0 9830.0 0.07 478181.0 -180000.0 -1.37 -0.9168 -0.669 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D16 mock treatment 490488.0 -68800.0 -0.5 592872.0 -65400.0 -0.5 -0.7074 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D17 compound treatment 528134.0 -31200.0 -0.23 582527.0 -75800.0 -0.58 -0.5683 -0.9177 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D18 compound treatment 569544.0 10200.0 0.07 625638.0 -32700.0 -0.25 -0.1226 -0.4727 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D19 compound treatment 648058.0 88800.0 0.65 660424.0 2110.0 0.02 0.4703 0.7243 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D20 compound treatment 630072.0 70800.0 0.52 609166.0 -49100.0 -0.37 0.102 0.1598 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D21 compound treatment 633593.0 74300.0 0.54 732610.0 74300.0 0.56 0.7833 0.9998 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D22 compound treatment 641583.0 82300.0 0.6 664988.0 6670.0 0.05 0.4613 0.764 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D23 compound treatment 634802.0 75500.0 0.55 625899.0 -32400.0 -0.25 0.2163 0.3578 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 D24 compound treatment 656039.0 96700.0 0.71 638579.0 -19700.0 -0.15 0.3942 0.5451 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E01 mock treatment 429706.0 -130000.0 -0.95 580247.0 -78100.0 -0.59 -1.0895 -0.9745 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E02 mock treatment 504029.0 -55300.0 -0.4 656373.0 -1940.0 -0.01 -0.2962 -0.7324 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E03 compound treatment 572017.0 12700.0 0.09 722128.0 63800.0 0.48 0.4086 0.8277 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E04 compound treatment 533851.0 -25400.0 -0.19 695492.0 37200.0 0.28 0.0681 0.2014 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E05 compound treatment 566551.0 7250.0 0.05 624831.0 -33500.0 -0.25 -0.1424 -0.5479 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E06 compound treatment 550490.0 -8810.0 -0.06 664756.0 6440.0 0.05 -0.011 -0.1354 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E07 compound treatment 525514.0 -33800.0 -0.25 554433.0 -104000.0 -0.79 -0.7327 -0.8861 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E08 compound treatment 523363.0 -35900.0 -0.26 643549.0 -14800.0 -0.11 -0.2652 -0.9279 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E09 mock treatment 486463.0 -72800.0 -0.53 563777.0 -94500.0 -0.72 -0.8845 -0.9892 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E10 mock treatment 554776.0 -4520.0 -0.03 634666.0 -23600.0 -0.18 -0.1504 -0.8235 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E11 compound treatment 546918.0 -12400.0 -0.09 631118.0 -27200.0 -0.21 -0.2101 -0.9315 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E12 compound treatment 283128.0 -276000.0 -2.02 312138.0 -346000.0 -2.63 -3.2877 -0.9915 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E13 compound treatment 536947.0 -22400.0 -0.16 576108.0 -82200.0 -0.62 -0.5572 -0.8631 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E14 compound treatment 576416.0 17100.0 0.13 624163.0 -34200.0 -0.26 -0.0949 -0.3296 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E15 compound treatment 130173.0 -429000.0 -3.14 129237.0 -529000.0 -4.02 -5.0611 -0.9925 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E16 compound treatment 549357.0 -9940.0 -0.07 585653.0 -72700.0 -0.55 -0.4417 -0.7934 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E17 mock treatment 549665.0 -9630.0 -0.07 658138.0 -177.0 0.0 -0.0508 -0.7204 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E18 mock treatment 594589.0 35300.0 0.26 586166.0 -72100.0 -0.55 -0.2051 -0.3385 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E19 compound treatment 223234.0 -336000.0 -2.46 197441.0 -461000.0 -3.5 -4.2135 -0.985 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E20 compound treatment 580122.0 20800.0 0.15 700375.0 42100.0 0.32 0.3336 0.9425 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E21 compound treatment 583760.0 24500.0 0.18 686803.0 28500.0 0.22 0.2795 0.9955 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E22 compound treatment 628527.0 69200.0 0.51 684050.0 25700.0 0.2 0.4962 0.9144 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E23 compound treatment 552424.0 -6880.0 -0.05 632605.0 -25700.0 -0.2 -0.1737 -0.8611 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 E24 compound treatment 532903.0 -26400.0 -0.19 653283.0 -5030.0 -0.04 -0.1635 -0.831 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F01 mock treatment 523383.0 -35900.0 -0.26 560557.0 -97800.0 -0.74 -0.7109 -0.9024 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F02 mock treatment 464177.0 -95100.0 -0.7 562656.0 -95700.0 -0.73 -1.0057 -0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F03 compound treatment 514038.0 -45300.0 -0.33 599546.0 -58800.0 -0.45 -0.5497 -0.9892 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F04 compound treatment 474100.0 -85200.0 -0.62 649191.0 -9120.0 -0.07 -0.4896 -0.7809 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F05 compound treatment 481107.0 -78200.0 -0.57 566221.0 -92100.0 -0.7 -0.8991 -0.995 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F06 compound treatment 496174.0 -63100.0 -0.46 667588.0 9270.0 0.07 -0.2766 -0.5923 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F07 compound treatment 546878.0 -12400.0 -0.09 689642.0 31300.0 0.24 0.104 0.4084 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F08 compound treatment 469333.0 -90000.0 -0.66 540935.0 -117000.0 -0.89 -1.0958 -0.9888 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F09 mock treatment 473927.0 -85400.0 -0.62 644069.0 -14200.0 -0.11 -0.518 -0.8175 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F10 mock treatment 519723.0 -39600.0 -0.29 641759.0 -16600.0 -0.13 -0.2936 -0.9303 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F11 compound treatment 486330.0 -73000.0 -0.53 697087.0 38800.0 0.29 -0.1691 -0.2774 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F12 compound treatment 508728.0 -50600.0 -0.37 504906.0 -153000.0 -1.17 -1.0856 -0.8879 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F13 compound treatment 539653.0 -19600.0 -0.14 566717.0 -91600.0 -0.7 -0.5936 -0.8355 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F14 compound treatment 508196.0 -51100.0 -0.37 508845.0 -149000.0 -1.14 -1.0672 -0.8927 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F15 compound treatment 406119.0 -153000.0 -1.12 490929.0 -167000.0 -1.27 -1.6913 -0.998 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F16 compound treatment 421333.0 -138000.0 -1.01 432610.0 -226000.0 -1.71 -1.9259 -0.968 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F17 mock treatment 525255.0 -34000.0 -0.25 624741.0 -33600.0 -0.26 -0.3564 -0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F18 mock treatment 553380.0 -5920.0 -0.04 521304.0 -137000.0 -1.04 -0.7666 -0.7359 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F19 compound treatment 487464.0 -71800.0 -0.53 563321.0 -95000.0 -0.72 -0.8818 -0.9878 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F20 compound treatment 620509.0 61200.0 0.45 779936.0 122000.0 0.92 0.9698 0.9447 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F21 compound treatment 639516.0 80200.0 0.59 748207.0 89900.0 0.68 0.8977 0.9971 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F22 compound treatment 626488.0 67200.0 0.49 647856.0 -10500.0 -0.08 0.2913 0.5852 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F23 compound treatment 453278.0 -106000.0 -0.78 497109.0 -161000.0 -1.22 -1.4142 -0.9757 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 F24 compound treatment 648098.0 88800.0 0.65 650473.0 -7840.0 -0.06 0.4171 0.6396 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G01 compound treatment 282413.0 -277000.0 -2.02 270740.0 -388000.0 -2.94 -3.5138 -0.9833 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G02 compound treatment 526514.0 -32800.0 -0.24 670001.0 11700.0 0.09 -0.1068 -0.4176 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G03 mock treatment 486230.0 -73100.0 -0.53 666782.0 8470.0 0.06 -0.3324 -0.6175 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G04 mock treatment 499133.0 -60200.0 -0.44 699662.0 41300.0 0.31 -0.089 -0.1647 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G05 compound treatment 502001.0 -57300.0 -0.42 614712.0 -43600.0 -0.33 -0.5305 -0.9932 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G06 compound treatment 490763.0 -68500.0 -0.5 614085.0 -44200.0 -0.34 -0.592 -0.9811 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G07 compound treatment 515935.0 -43400.0 -0.32 722732.0 64400.0 0.49 0.1218 0.2088 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G08 compound treatment 430774.0 -129000.0 -0.94 539341.0 -119000.0 -0.9 -1.3037 -0.9998 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G09 compound treatment 551696.0 -7600.0 -0.06 658977.0 662.0 0.01 -0.0358 -0.6405 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G10 compound treatment 607167.0 47900.0 0.35 681314.0 23000.0 0.17 0.3711 0.9485 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G11 compound treatment 478569.0 -80700.0 -0.59 577521.0 -80800.0 -0.61 -0.8515 -0.9998 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G12 compound treatment 526291.0 -33000.0 -0.24 721452.0 63100.0 0.48 0.1685 0.3137 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G13 compound treatment 550333.0 -8970.0 -0.07 652501.0 -5810.0 -0.04 -0.0776 -0.9815 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G14 compound treatment 523047.0 -36300.0 -0.27 720525.0 62200.0 0.47 0.1467 0.2707 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G15 compound treatment 606982.0 47700.0 0.35 719958.0 61600.0 0.47 0.5777 0.9895 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G16 compound treatment 529342.0 -30000.0 -0.22 779986.0 122000.0 0.92 0.4987 0.525 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G17 compound treatment 408174.0 -151000.0 -1.11 517796.0 -141000.0 -1.07 -1.5363 -0.9998 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G18 compound treatment 565995.0 6700.0 0.05 658819.0 504.0 0.0 0.0373 0.7601 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G19 mock treatment 579488.0 20200.0 0.15 688149.0 29800.0 0.23 0.2647 0.9784 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G20 mock treatment 548317.0 -11000.0 -0.08 643227.0 -15100.0 -0.11 -0.1378 -0.9849 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G21 compound treatment 605580.0 46300.0 0.34 695683.0 37400.0 0.28 0.4401 0.9962 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G22 compound treatment 643576.0 84300.0 0.62 728747.0 70400.0 0.54 0.8141 0.9975 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G23 compound treatment 592070.0 32800.0 0.24 623574.0 -34700.0 -0.26 -0.0172 -0.0481 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 G24 compound treatment 538475.0 -20800.0 -0.15 654704.0 -3610.0 -0.03 -0.1271 -0.8212 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H01 compound treatment 487192.0 -72100.0 -0.53 574819.0 -83500.0 -0.63 -0.8214 -0.9958 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H02 compound treatment 480905.0 -78400.0 -0.57 600353.0 -58000.0 -0.44 -0.7167 -0.9915 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H03 mock treatment 452077.0 -107000.0 -0.78 466711.0 -192000.0 -1.46 -1.5837 -0.9579 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H04 mock treatment 466939.0 -92400.0 -0.68 624444.0 -33900.0 -0.26 -0.6596 -0.9125 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H05 compound treatment 514261.0 -45000.0 -0.33 655624.0 -2690.0 -0.02 -0.2474 -0.7495 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H06 compound treatment 574090.0 14800.0 0.11 583042.0 -75300.0 -0.57 -0.3279 -0.5634 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H07 compound treatment 461999.0 -97300.0 -0.71 528431.0 -130000.0 -0.99 -1.2009 -0.9871 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H08 compound treatment 593503.0 34200.0 0.25 690350.0 32000.0 0.24 0.349 0.9999 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H09 compound treatment 474656.0 -84600.0 -0.62 513622.0 -145000.0 -1.1 -1.215 -0.9631 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H10 compound treatment 559385.0 85.1 0.0 549574.0 -109000.0 -0.83 -0.5837 -0.7066 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H11 compound treatment 516636.0 -42700.0 -0.31 566645.0 -91700.0 -0.7 -0.713 -0.9344 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H12 compound treatment 536837.0 -22500.0 -0.16 532451.0 -126000.0 -0.96 -0.7923 -0.8166 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H13 compound treatment 582338.0 23000.0 0.17 725341.0 67000.0 0.51 0.4792 0.8934 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H14 compound treatment 543920.0 -15400.0 -0.11 600185.0 -58100.0 -0.44 -0.3918 -0.8598 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H15 compound treatment 662529.0 103000.0 0.75 664319.0 6000.0 0.05 0.5661 0.7485 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H16 compound treatment 595050.0 35800.0 0.26 701269.0 43000.0 0.33 0.4156 0.994 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H17 compound treatment 673675.0 114000.0 0.84 676303.0 18000.0 0.14 0.6881 0.8119 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H18 compound treatment 494441.0 -64900.0 -0.47 498674.0 -160000.0 -1.21 -1.1929 -0.9161 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H19 mock treatment 608792.0 49500.0 0.36 616283.0 -42000.0 -0.32 0.0301 0.0625 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H20 mock treatment 605088.0 45800.0 0.33 557132.0 -101000.0 -0.77 -0.3067 -0.3659 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H21 compound treatment 590742.0 31400.0 0.23 613206.0 -45100.0 -0.34 -0.0797 -0.1932 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H22 compound treatment 566684.0 7380.0 0.05 644763.0 -13600.0 -0.1 -0.0346 -0.2977 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H23 compound treatment 580041.0 20700.0 0.15 615426.0 -42900.0 -0.33 -0.1231 -0.3426 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 H24 compound treatment 549399.0 -9900.0 -0.07 548563.0 -110000.0 -0.83 -0.6408 -0.7656 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I01 compound treatment 294903.0 -264000.0 -1.93 340972.0 -317000.0 -2.41 -3.0719 -0.994 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I02 compound treatment 508729.0 -50600.0 -0.37 639381.0 -18900.0 -0.14 -0.3632 -0.9153 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I03 compound treatment 515109.0 -44200.0 -0.32 229928.0 -428000.0 -3.25 -2.5297 -0.7735 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I04 compound treatment 503163.0 -56100.0 -0.41 673971.0 15700.0 0.12 -0.2062 -0.4824 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I05 mock treatment 536931.0 -22400.0 -0.16 689632.0 31300.0 0.24 0.0526 0.182 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I06 mock treatment 595632.0 36300.0 0.27 775283.0 117000.0 0.89 0.8162 0.88 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I07 compound treatment 539915.0 -19400.0 -0.14 695252.0 36900.0 0.28 0.0982 0.3123 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I08 compound treatment 599853.0 40600.0 0.3 631965.0 -26300.0 -0.2 0.0682 0.1905 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I09 compound treatment 593202.0 33900.0 0.25 698945.0 40600.0 0.31 0.3936 0.9941 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I10 compound treatment 614034.0 54700.0 0.4 550952.0 -107000.0 -0.82 -0.2937 -0.3233 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I11 compound treatment 644733.0 85400.0 0.62 631285.0 -27000.0 -0.21 0.2966 0.451 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I12 compound treatment 628179.0 68900.0 0.5 736960.0 78600.0 0.6 0.7786 0.9964 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I13 compound treatment 595360.0 36100.0 0.26 786944.0 129000.0 0.98 0.8774 0.8669 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I14 compound treatment 536601.0 -22700.0 -0.17 643124.0 -15200.0 -0.12 -0.199 -0.9842 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I15 compound treatment 238411.0 -321000.0 -2.35 297499.0 -361000.0 -2.74 -3.5976 -0.997 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I16 compound treatment 590643.0 31300.0 0.23 693147.0 34800.0 0.26 0.3492 0.9974 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I17 compound treatment 603062.0 43800.0 0.32 770443.0 112000.0 0.85 0.8286 0.9106 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I18 compound treatment 604496.0 45200.0 0.33 630802.0 -27500.0 -0.21 0.0859 0.2197 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I19 compound treatment 579585.0 20300.0 0.15 752139.0 93800.0 0.71 0.6089 0.8364 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I20 compound treatment 584419.0 25100.0 0.18 696209.0 37900.0 0.29 0.3335 0.9765 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I21 mock treatment 564143.0 4840.0 0.04 660530.0 2220.0 0.02 0.0369 0.9421 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I22 mock treatment 562437.0 3140.0 0.02 652061.0 -6250.0 -0.05 -0.0174 -0.3293 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I23 compound treatment 570021.0 10700.0 0.08 644919.0 -13400.0 -0.1 -0.0165 -0.1286 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 I24 compound treatment 557368.0 -1930.0 -0.01 571178.0 -87100.0 -0.66 -0.4781 -0.722 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J01 compound treatment 544893.0 -14400.0 -0.11 708418.0 50100.0 0.38 0.1946 0.4928 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J02 compound treatment 548995.0 -10300.0 -0.08 695848.0 37500.0 0.29 0.1483 0.5029 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J03 compound treatment 553319.0 -5980.0 -0.04 565126.0 -93200.0 -0.71 -0.5315 -0.7494 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J04 compound treatment 476218.0 -83100.0 -0.61 641158.0 -17200.0 -0.13 -0.5218 -0.8397 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J05 mock treatment 492175.0 -67100.0 -0.49 669522.0 11200.0 0.09 -0.2869 -0.5759 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J06 mock treatment 531844.0 -27500.0 -0.2 732369.0 74100.0 0.56 0.2558 0.4283 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J07 compound treatment 553125.0 -6170.0 -0.05 669168.0 10900.0 0.08 0.0264 0.2805 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J08 compound treatment 580474.0 21200.0 0.15 702772.0 44500.0 0.34 0.3483 0.9375 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J09 compound treatment 556153.0 -3150.0 -0.02 710472.0 52200.0 0.4 0.2639 0.6649 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J10 compound treatment 593063.0 33800.0 0.25 617440.0 -40900.0 -0.31 -0.045 -0.1134 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J11 compound treatment 496137.0 -63200.0 -0.46 709803.0 51500.0 0.39 -0.05 -0.0827 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J12 compound treatment 189790.0 -370000.0 -2.7 216795.0 -442000.0 -3.35 -4.2825 -0.9943 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J13 compound treatment 601368.0 42100.0 0.31 577981.0 -80300.0 -0.61 -0.214 -0.3131 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J14 compound treatment 572642.0 13300.0 0.1 555955.0 -102000.0 -0.78 -0.4809 -0.6136 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J15 compound treatment 528907.0 -30400.0 -0.22 589133.0 -69200.0 -0.53 -0.5288 -0.9267 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J16 compound treatment 552733.0 -6570.0 -0.05 592341.0 -66000.0 -0.5 -0.3884 -0.7713 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J17 compound treatment 621266.0 62000.0 0.45 677354.0 19000.0 0.14 0.4227 0.8886 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J18 compound treatment 505522.0 -53800.0 -0.39 609026.0 -49300.0 -0.37 -0.5429 -0.9997 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J19 compound treatment 738630.0 179000.0 1.31 711511.0 53200.0 0.4 1.2131 0.884 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J20 compound treatment 669519.0 110000.0 0.81 693102.0 34800.0 0.26 0.7568 0.8922 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J21 mock treatment 616862.0 57600.0 0.42 575219.0 -83100.0 -0.63 -0.1487 -0.196 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J22 mock treatment 617025.0 57700.0 0.42 612421.0 -45900.0 -0.35 0.052 0.0949 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J23 compound treatment 595819.0 36500.0 0.27 561205.0 -97100.0 -0.74 -0.3328 -0.4242 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 J24 compound treatment 617362.0 58100.0 0.42 693828.0 35500.0 0.27 0.491 0.976 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K01 compound treatment 485340.0 -74000.0 -0.54 524199.0 -134000.0 -1.02 -1.1029 -0.9561 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K02 compound treatment 598873.0 39600.0 0.29 659201.0 886.0 0.01 0.2094 0.7234 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K03 compound treatment 526443.0 -32900.0 -0.24 751868.0 93600.0 0.71 0.3326 0.4434 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K04 compound treatment 647445.0 88100.0 0.64 676804.0 18500.0 0.14 0.5551 0.8414 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K05 compound treatment 163953.0 -395000.0 -2.89 176970.0 -481000.0 -3.66 -4.6301 -0.9932 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K06 compound treatment 638531.0 79200.0 0.58 680083.0 21800.0 0.17 0.5266 0.874 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K07 mock treatment 626274.0 67000.0 0.49 593635.0 -64700.0 -0.49 -0.0011 -0.0016 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K08 mock treatment 652195.0 92900.0 0.68 677726.0 19400.0 0.15 0.5846 0.841 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K09 compound treatment 604279.0 45000.0 0.33 574272.0 -84000.0 -0.64 -0.2189 -0.3047 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K10 compound treatment 757081.0 198000.0 1.45 834199.0 176000.0 1.34 1.9676 0.9992 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K11 compound treatment 147190.0 -412000.0 -3.01 129719.0 -529000.0 -4.02 -4.9706 -0.99 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K12 compound treatment 518124.0 -41200.0 -0.3 608897.0 -49400.0 -0.38 -0.4784 -0.994 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K13 compound treatment 598177.0 38900.0 0.28 779110.0 121000.0 0.92 0.8499 0.8847 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K14 compound treatment 598155.0 38900.0 0.28 629627.0 -28700.0 -0.22 0.0468 0.1308 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K15 mock treatment 678824.0 120000.0 0.87 778935.0 121000.0 0.92 1.266 0.9997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K16 mock treatment 618070.0 58800.0 0.43 748606.0 90300.0 0.69 0.7889 0.9746 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K17 compound treatment 698741.0 139000.0 1.02 716510.0 58200.0 0.44 1.0337 0.93 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K18 compound treatment 619400.0 60100.0 0.44 612912.0 -45400.0 -0.34 0.0669 0.1197 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K19 compound treatment 586097.0 26800.0 0.2 690746.0 32400.0 0.25 0.3128 0.9936 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K20 compound treatment 704789.0 145000.0 1.06 700646.0 42300.0 0.32 0.9797 0.8814 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K21 compound treatment 597060.0 37800.0 0.28 605667.0 -52600.0 -0.4 -0.0875 -0.1801 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K22 compound treatment 535890.0 -23400.0 -0.17 387480.0 -271000.0 -2.06 -1.5759 -0.7633 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K23 mock treatment 515378.0 -43900.0 -0.32 633735.0 -24600.0 -0.19 -0.3592 -0.9667 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 K24 mock treatment 552206.0 -7090.0 -0.05 639740.0 -18600.0 -0.14 -0.1365 -0.9077 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L01 compound treatment 588231.0 28900.0 0.21 666666.0 8350.0 0.06 0.1945 0.8804 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L02 compound treatment 572165.0 12900.0 0.09 674011.0 15700.0 0.12 0.1508 0.9931 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L03 compound treatment 592561.0 33300.0 0.24 713668.0 55400.0 0.42 0.4693 0.9661 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L04 compound treatment 481753.0 -77500.0 -0.57 648423.0 -9890.0 -0.08 -0.4541 -0.7939 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L05 compound treatment 579939.0 20600.0 0.15 709726.0 51400.0 0.39 0.3829 0.9145 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L06 compound treatment 534563.0 -24700.0 -0.18 623755.0 -34600.0 -0.26 -0.3136 -0.9835 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L07 mock treatment 636742.0 77400.0 0.57 644701.0 -13600.0 -0.1 0.3273 0.5686 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L08 mock treatment 565597.0 6300.0 0.05 693305.0 35000.0 0.27 0.2205 0.8174 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L09 compound treatment 598050.0 38800.0 0.28 641122.0 -17200.0 -0.13 0.108 0.3462 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L10 compound treatment 551895.0 -7400.0 -0.05 564483.0 -93800.0 -0.71 -0.5423 -0.7586 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L11 compound treatment 572575.0 13300.0 0.1 648335.0 -9980.0 -0.08 0.015 0.1221 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L12 compound treatment 596104.0 36800.0 0.27 582937.0 -75400.0 -0.57 -0.2146 -0.3391 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L13 compound treatment 587621.0 28300.0 0.21 739588.0 81300.0 0.62 0.583 0.8953 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L14 compound treatment 596316.0 37000.0 0.27 686376.0 28100.0 0.21 0.3422 0.993 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L15 mock treatment 655348.0 96000.0 0.7 724015.0 65700.0 0.5 0.8496 0.986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L16 mock treatment 619917.0 60600.0 0.44 732141.0 73800.0 0.56 0.71 0.9932 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L17 compound treatment 667838.0 109000.0 0.79 684597.0 26300.0 0.2 0.7024 0.8582 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L18 compound treatment 601053.0 41800.0 0.31 685343.0 27000.0 0.21 0.3611 0.9814 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L19 compound treatment 558179.0 -1120.0 -0.01 710326.0 52000.0 0.4 0.2736 0.6923 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L20 compound treatment 594450.0 35200.0 0.26 684663.0 26300.0 0.2 0.3233 0.9923 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L21 compound treatment 566204.0 6900.0 0.05 762099.0 104000.0 0.79 0.5932 0.7509 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L22 compound treatment 654309.0 95000.0 0.69 772698.0 114000.0 0.87 1.1057 0.9939 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L23 mock treatment 619431.0 60100.0 0.44 687402.0 29100.0 0.22 0.4672 0.9493 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 L24 mock treatment 575625.0 16300.0 0.12 649872.0 -8440.0 -0.06 0.0391 0.2883 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M01 compound treatment 581558.0 22300.0 0.16 665969.0 7650.0 0.06 0.1562 0.9038 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M02 compound treatment 561208.0 1910.0 0.01 710316.0 52000.0 0.4 0.2892 0.7316 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M03 compound treatment 634144.0 74800.0 0.55 807649.0 149000.0 1.13 1.1892 0.9441 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M04 compound treatment 606007.0 46700.0 0.34 765592.0 107000.0 0.81 0.8178 0.9255 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M05 compound treatment 622776.0 63500.0 0.46 742290.0 84000.0 0.64 0.7793 0.9878 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M06 compound treatment 594898.0 35600.0 0.26 651774.0 -6540.0 -0.05 0.1489 0.562 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M07 compound treatment 597675.0 38400.0 0.28 656776.0 -1540.0 -0.01 0.1902 0.6771 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M08 compound treatment 634872.0 75600.0 0.55 778590.0 120000.0 0.91 1.0369 0.971 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M09 mock treatment 626793.0 67500.0 0.49 748999.0 90700.0 0.69 0.8361 0.9866 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M10 mock treatment 592220.0 32900.0 0.24 798642.0 140000.0 1.07 0.924 0.8455 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M11 compound treatment 535797.0 -23500.0 -0.17 651071.0 -7240.0 -0.06 -0.1604 -0.889 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M12 compound treatment 586990.0 27700.0 0.2 845838.0 188000.0 1.42 1.1505 0.7996 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M13 mock treatment 627421.0 68100.0 0.5 783058.0 125000.0 0.95 1.0224 0.9549 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M14 mock treatment 594170.0 34900.0 0.26 600870.0 -57400.0 -0.44 -0.1283 -0.2538 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M15 compound treatment 645292.0 86000.0 0.63 726558.0 68200.0 0.52 0.8113 0.9954 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M16 compound treatment 690501.0 131000.0 0.96 633988.0 -24300.0 -0.18 0.5478 0.5606 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M17 compound treatment 699536.0 140000.0 1.03 773501.0 115000.0 0.88 1.3439 0.9969 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M18 compound treatment 624989.0 65700.0 0.48 659818.0 1500.0 0.01 0.3478 0.7237 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M19 compound treatment 641536.0 82200.0 0.6 834790.0 176000.0 1.34 1.3732 0.9346 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M20 compound treatment 704891.0 146000.0 1.06 776965.0 119000.0 0.9 1.3902 0.9966 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M21 compound treatment 618280.0 59000.0 0.43 677010.0 18700.0 0.14 0.4054 0.8928 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M22 compound treatment 690501.0 131000.0 0.96 684279.0 26000.0 0.2 0.8179 0.835 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M23 compound treatment 539490.0 -19800.0 -0.14 637338.0 -21000.0 -0.16 -0.2151 -0.9989 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 M24 compound treatment 450550.0 -109000.0 -0.8 485729.0 -173000.0 -1.31 -1.4894 -0.9713 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N01 compound treatment 511308.0 -48000.0 -0.35 693765.0 35500.0 0.27 -0.0577 -0.1305 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N02 compound treatment 526211.0 -33100.0 -0.24 747840.0 89500.0 0.68 0.3098 0.4292 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N03 compound treatment 564890.0 5590.0 0.04 649365.0 -8950.0 -0.07 -0.0192 -0.2416 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N04 compound treatment 607609.0 48300.0 0.35 851192.0 193000.0 1.47 1.2859 0.8532 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N05 compound treatment 625844.0 66500.0 0.49 657454.0 -861.0 -0.01 0.3395 0.6975 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N06 compound treatment 599805.0 40500.0 0.3 797444.0 139000.0 1.06 0.9568 0.8717 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N07 compound treatment 601805.0 42500.0 0.31 811842.0 154000.0 1.17 1.0445 0.8654 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N08 compound treatment 618262.0 59000.0 0.43 676694.0 18400.0 0.14 0.4036 0.8905 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N09 mock treatment 601203.0 41900.0 0.31 775955.0 118000.0 0.89 0.8486 0.8982 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N10 mock treatment 557664.0 -1640.0 -0.01 694570.0 36300.0 0.28 0.1863 0.6758 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N11 compound treatment 623183.0 63900.0 0.47 731477.0 73200.0 0.56 0.7234 0.9963 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N12 compound treatment 153043.0 -406000.0 -2.97 125369.0 -533000.0 -4.05 -4.9637 -0.9884 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N13 mock treatment 539941.0 -19400.0 -0.14 747430.0 89100.0 0.68 0.3786 0.5474 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N14 mock treatment 554352.0 -4950.0 -0.04 689047.0 30700.0 0.23 0.1395 0.5905 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N15 compound treatment 548498.0 -10800.0 -0.08 600884.0 -57400.0 -0.44 -0.3644 -0.8218 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N16 compound treatment 772411.0 213000.0 1.56 618785.0 -39500.0 -0.3 0.8897 0.5605 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N17 compound treatment 614194.0 54900.0 0.4 682131.0 23800.0 0.18 0.4118 0.9352 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N18 compound treatment 116723.0 -443000.0 -3.24 118929.0 -539000.0 -4.1 -5.1861 -0.9932 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N19 compound treatment 598532.0 39200.0 0.29 692739.0 34400.0 0.26 0.3878 0.9989 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N20 compound treatment 687322.0 128000.0 0.94 742798.0 84500.0 0.64 1.1158 0.983 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N21 compound treatment 622906.0 63600.0 0.47 742114.0 83800.0 0.64 0.7791 0.9881 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N22 compound treatment 119833.0 -439000.0 -3.21 151169.0 -507000.0 -3.85 -4.9968 -0.9959 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N23 compound treatment 587563.0 28300.0 0.21 645729.0 -12600.0 -0.1 0.0785 0.3449 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 N24 compound treatment 107305.0 -452000.0 -3.31 140381.0 -518000.0 -3.93 -5.1195 -0.9962 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O01 compound treatment 633825.0 74500.0 0.55 712025.0 53700.0 0.41 0.6739 0.9898 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O02 compound treatment 603386.0 44100.0 0.32 587425.0 -70900.0 -0.54 -0.1528 -0.2435 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O03 compound treatment 610429.0 51100.0 0.37 692173.0 33900.0 0.26 0.4463 0.9833 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O04 compound treatment 639686.0 80400.0 0.59 772906.0 115000.0 0.87 1.0312 0.9817 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O05 compound treatment 686384.0 127000.0 0.93 835469.0 177000.0 1.35 1.6088 0.9837 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O06 compound treatment 707147.0 148000.0 1.08 806636.0 148000.0 1.13 1.5613 0.9998 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O07 compound treatment 625167.0 65900.0 0.48 753871.0 95600.0 0.73 0.8539 0.9802 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O08 compound treatment 583801.0 24500.0 0.18 741819.0 83500.0 0.63 0.5753 0.8727 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O09 compound treatment 746519.0 187000.0 1.37 732411.0 74100.0 0.56 1.3662 0.9229 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O10 compound treatment 653013.0 93700.0 0.69 838960.0 181000.0 1.37 1.455 0.9485 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O11 mock treatment 575343.0 16000.0 0.12 859720.0 201000.0 1.53 1.1649 0.7591 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O12 mock treatment 634549.0 75200.0 0.55 804759.0 146000.0 1.11 1.1758 0.9473 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O13 compound treatment 660153.0 101000.0 0.74 887429.0 229000.0 1.74 1.7523 0.927 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O14 compound treatment 762144.0 203000.0 1.48 747935.0 89600.0 0.68 1.5304 0.9376 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O15 compound treatment 592964.0 33700.0 0.25 860941.0 203000.0 1.54 1.2625 0.8099 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O16 compound treatment 671958.0 113000.0 0.82 714743.0 56400.0 0.43 0.8857 0.9537 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O17 compound treatment 594850.0 35600.0 0.26 778368.0 120000.0 0.91 0.8287 0.8739 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O18 compound treatment 595407.0 36100.0 0.26 729255.0 70900.0 0.54 0.5678 0.9461 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O19 compound treatment 536542.0 -22800.0 -0.17 576921.0 -81400.0 -0.62 -0.5549 -0.8666 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O20 compound treatment 701724.0 142000.0 1.04 807647.0 149000.0 1.13 1.5387 0.9991 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O21 compound treatment 715085.0 156000.0 1.14 732193.0 73900.0 0.56 1.2024 0.9468 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O22 compound treatment 579103.0 19800.0 0.14 588897.0 -69400.0 -0.53 -0.2705 -0.4946 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O23 compound treatment 529373.0 -29900.0 -0.22 722122.0 63800.0 0.48 0.188 0.3535 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 O24 compound treatment 540916.0 -18400.0 -0.13 577966.0 -80300.0 -0.61 -0.5267 -0.8427 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P01 compound treatment 721288.0 162000.0 1.18 622412.0 -35900.0 -0.27 0.6448 0.5304 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P02 compound treatment 159100.0 -400000.0 -2.93 129365.0 -529000.0 -4.02 -4.9109 -0.9879 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P03 compound treatment 660127.0 101000.0 0.74 783449.0 125000.0 0.95 1.1936 0.9921 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P04 compound treatment 567659.0 8360.0 0.06 675962.0 17600.0 0.13 0.138 0.9367 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P05 compound treatment 645373.0 86100.0 0.63 782696.0 124000.0 0.94 1.1132 0.9805 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P06 compound treatment 256974.0 -302000.0 -2.21 229438.0 -429000.0 -3.26 -3.8672 -0.9822 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P07 compound treatment 600624.0 41300.0 0.3 707788.0 49500.0 0.38 0.4795 0.9942 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P08 compound treatment 411588.0 -148000.0 -1.08 405892.0 -252000.0 -1.92 -2.1198 -0.9631 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P09 compound treatment 788688.0 229000.0 1.68 866703.0 208000.0 1.58 2.3056 0.9996 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P10 compound treatment 591550.0 32300.0 0.24 651572.0 -6740.0 -0.05 0.1306 0.5409 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P11 mock treatment 642959.0 83700.0 0.61 744757.0 86400.0 0.66 0.897 0.9994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P12 mock treatment 649321.0 90000.0 0.66 759588.0 101000.0 0.77 1.0095 0.997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P13 compound treatment 656419.0 97100.0 0.71 748371.0 90100.0 0.68 0.986 0.9998 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P14 compound treatment 523926.0 -35400.0 -0.26 764420.0 106000.0 0.81 0.387 0.4572 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P15 compound treatment 571610.0 12300.0 0.09 807707.0 149000.0 1.13 0.8662 0.7608 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P16 compound treatment 656380.0 97100.0 0.71 718492.0 60200.0 0.46 0.8253 0.9773 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P17 compound treatment 639385.0 80100.0 0.59 740593.0 82300.0 0.63 0.8561 0.9995 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P18 compound treatment 661054.0 102000.0 0.74 646467.0 -11800.0 -0.09 0.4625 0.6171 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P19 compound treatment 619219.0 59900.0 0.44 814587.0 156000.0 1.19 1.1493 0.9082 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P20 compound treatment 432746.0 -127000.0 -0.93 299751.0 -359000.0 -2.72 -2.5805 -0.897 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P21 compound treatment 656774.0 97500.0 0.71 683233.0 24900.0 0.19 0.6379 0.8649 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P22 compound treatment 623679.0 64400.0 0.47 752211.0 93900.0 0.71 0.8373 0.9797 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P23 compound treatment 597961.0 38700.0 0.28 706884.0 48600.0 0.37 0.4608 0.9914 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2098 P24 compound treatment 248149.0 -311000.0 -2.28 491553.0 -167000.0 -1.27 -2.5048 -0.9618 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A01 compound treatment 488098.0 -119000.0 -0.87 651314.0 -32000.0 -0.24 -0.7871 -0.8711 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A02 compound treatment 478394.0 -129000.0 -0.94 584449.0 -98800.0 -0.75 -1.1965 -0.9937 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A03 compound treatment 512634.0 -94500.0 -0.69 671795.0 -11500.0 -0.09 -0.5502 -0.7901 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A04 compound treatment 537541.0 -69600.0 -0.51 596279.0 -87000.0 -0.66 -0.827 -0.9916 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A05 compound treatment 552782.0 -54300.0 -0.4 553122.0 -130000.0 -0.99 -0.9801 -0.9197 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A06 compound treatment 498644.0 -108000.0 -0.79 575061.0 -108000.0 -0.82 -1.1422 -0.9998 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A07 compound treatment 591409.0 -15700.0 -0.11 514012.0 -169000.0 -1.29 -0.9904 -0.7672 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A08 compound treatment 529702.0 -77400.0 -0.57 488182.0 -195000.0 -1.48 -1.4483 -0.9128 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A09 compound treatment 608693.0 1590.0 0.01 582530.0 -101000.0 -0.77 -0.533 -0.6963 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A10 compound treatment 545569.0 -61500.0 -0.45 515967.0 -167000.0 -1.27 -1.2169 -0.9025 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A11 compound treatment 473887.0 -133000.0 -0.97 622369.0 -60900.0 -0.46 -1.0161 -0.9421 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A12 compound treatment 526234.0 -80900.0 -0.59 520299.0 -163000.0 -1.24 -1.2937 -0.9428 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A13 mock treatment 585649.0 -21500.0 -0.16 673729.0 -9550.0 -0.07 -0.1622 -0.9386 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A14 mock treatment 566613.0 -40500.0 -0.3 540854.0 -142000.0 -1.08 -0.9744 -0.8687 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A15 compound treatment 608358.0 1260.0 0.01 566424.0 -117000.0 -0.89 -0.6212 -0.6997 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A16 compound treatment 563717.0 -43400.0 -0.32 558995.0 -124000.0 -0.94 -0.892 -0.8955 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A17 compound treatment 555814.0 -51300.0 -0.38 701653.0 18400.0 0.14 -0.1665 -0.4161 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A18 compound treatment 641426.0 34300.0 0.25 607088.0 -76200.0 -0.58 -0.2318 -0.3674 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A19 compound treatment 668834.0 61700.0 0.45 684537.0 1260.0 0.01 0.326 0.7219 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A20 compound treatment 441680.0 -165000.0 -1.21 514774.0 -169000.0 -1.28 -1.7606 -0.9996 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A21 compound treatment 598388.0 -8710.0 -0.06 549675.0 -134000.0 -1.01 -0.7627 -0.75 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A22 compound treatment 579634.0 -27500.0 -0.2 589327.0 -94000.0 -0.71 -0.6467 -0.8722 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A23 compound treatment 594165.0 -12900.0 -0.09 503072.0 -180000.0 -1.37 -1.0349 -0.7542 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 A24 compound treatment 522691.0 -84400.0 -0.62 516928.0 -166000.0 -1.26 -1.3301 -0.9457 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B01 compound treatment 523579.0 -83500.0 -0.61 666684.0 -16600.0 -0.13 -0.5211 -0.8355 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B02 compound treatment 547743.0 -59400.0 -0.43 759085.0 75800.0 0.58 0.1003 0.139 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B03 compound treatment 460273.0 -147000.0 -1.07 624649.0 -58600.0 -0.45 -1.0742 -0.9241 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B04 compound treatment 576035.0 -31100.0 -0.23 621061.0 -62200.0 -0.47 -0.4949 -0.9436 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B05 compound treatment 546245.0 -60900.0 -0.45 588907.0 -94400.0 -0.72 -0.8216 -0.9737 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B06 compound treatment 520927.0 -86200.0 -0.63 586968.0 -96300.0 -0.73 -0.963 -0.9972 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B07 compound treatment 509608.0 -97500.0 -0.71 591515.0 -91800.0 -0.7 -0.9971 -0.9999 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B08 compound treatment 512248.0 -94900.0 -0.69 535672.0 -148000.0 -1.12 -1.2834 -0.9733 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B09 compound treatment 538731.0 -68400.0 -0.5 602713.0 -80600.0 -0.61 -0.7863 -0.995 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B10 compound treatment 570703.0 -36400.0 -0.27 541929.0 -141000.0 -1.07 -0.9475 -0.8565 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B11 compound treatment 620785.0 13700.0 0.1 562547.0 -121000.0 -0.92 -0.5778 -0.6262 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B12 compound treatment 485827.0 -121000.0 -0.89 571142.0 -112000.0 -0.85 -1.2295 -0.9998 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B13 mock treatment 542669.0 -64400.0 -0.47 627720.0 -55600.0 -0.42 -0.6316 -0.9985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B14 mock treatment 539211.0 -67900.0 -0.5 674009.0 -9270.0 -0.07 -0.4009 -0.7994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B15 compound treatment 646020.0 38900.0 0.28 685589.0 2310.0 0.02 0.2137 0.7492 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B16 compound treatment 587048.0 -20100.0 -0.15 556330.0 -127000.0 -0.96 -0.7856 -0.8054 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B17 compound treatment 571901.0 -35200.0 -0.26 565215.0 -118000.0 -0.9 -0.8162 -0.8747 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B18 compound treatment 550265.0 -56800.0 -0.42 603211.0 -80100.0 -0.61 -0.724 -0.9828 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B19 compound treatment 561432.0 -45700.0 -0.33 632003.0 -51300.0 -0.39 -0.5116 -0.9971 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B20 compound treatment 535685.0 -71400.0 -0.52 529962.0 -153000.0 -1.16 -1.1929 -0.9345 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B21 compound treatment 533965.0 -73100.0 -0.53 654813.0 -28500.0 -0.22 -0.5311 -0.9206 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B22 compound treatment 532388.0 -74700.0 -0.55 577924.0 -105000.0 -0.8 -0.9523 -0.9827 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B23 compound treatment 568427.0 -38700.0 -0.28 633409.0 -49900.0 -0.38 -0.4679 -0.9896 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 B24 compound treatment 562245.0 -44900.0 -0.33 528645.0 -155000.0 -1.17 -1.0626 -0.8712 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C01 compound treatment 544031.0 -63100.0 -0.46 579346.0 -104000.0 -0.79 -0.8844 -0.9672 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C02 compound treatment 483924.0 -123000.0 -0.9 443583.0 -240000.0 -1.82 -1.9246 -0.9473 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C03 compound treatment 508978.0 -98100.0 -0.72 554290.0 -129000.0 -0.98 -1.2003 -0.9883 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C04 compound treatment 525706.0 -81400.0 -0.6 535435.0 -148000.0 -1.12 -1.2151 -0.9559 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C05 compound treatment 627709.0 20600.0 0.15 572117.0 -111000.0 -0.84 -0.4906 -0.5719 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C06 compound treatment 539347.0 -67800.0 -0.5 599790.0 -83500.0 -0.63 -0.7988 -0.9925 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C07 compound treatment 524935.0 -82200.0 -0.6 570359.0 -113000.0 -0.86 -1.0315 -0.9848 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C08 compound treatment 506997.0 -100000.0 -0.73 563308.0 -120000.0 -0.91 -1.1621 -0.9941 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C09 compound treatment 570386.0 -36700.0 -0.27 608575.0 -74700.0 -0.57 -0.5912 -0.9416 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C10 compound treatment 449883.0 -157000.0 -1.15 623539.0 -59700.0 -0.45 -1.1339 -0.9173 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C11 mock treatment 550039.0 -57100.0 -0.42 633765.0 -49500.0 -0.38 -0.5611 -0.9987 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C12 mock treatment 566502.0 -40600.0 -0.3 636963.0 -46300.0 -0.35 -0.4587 -0.9964 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C13 compound treatment 514958.0 -92100.0 -0.67 609623.0 -73700.0 -0.56 -0.8721 -0.9957 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C14 compound treatment 657193.0 50100.0 0.37 592148.0 -91100.0 -0.69 -0.2305 -0.2943 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C15 mock treatment 606029.0 -1070.0 -0.01 622201.0 -61100.0 -0.46 -0.3336 -0.7189 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C16 mock treatment 611069.0 3970.0 0.03 578975.0 -104000.0 -0.79 -0.5398 -0.6807 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C17 compound treatment 547668.0 -59400.0 -0.43 561890.0 -121000.0 -0.92 -0.9594 -0.9411 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C18 compound treatment 598441.0 -8660.0 -0.06 594703.0 -88600.0 -0.67 -0.5206 -0.7702 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C19 compound treatment 634818.0 27700.0 0.2 574862.0 -108000.0 -0.82 -0.4391 -0.5176 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C20 compound treatment 572471.0 -34600.0 -0.25 524829.0 -158000.0 -1.2 -1.0302 -0.8375 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C21 compound treatment 608861.0 1760.0 0.01 614303.0 -69000.0 -0.52 -0.3614 -0.6895 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C22 compound treatment 578936.0 -28200.0 -0.21 561952.0 -121000.0 -0.92 -0.7974 -0.8443 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C23 compound treatment 621004.0 13900.0 0.1 559988.0 -123000.0 -0.94 -0.5904 -0.6267 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 C24 compound treatment 539389.0 -67700.0 -0.5 628206.0 -55100.0 -0.42 -0.646 -0.9965 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D01 compound treatment 484337.0 -123000.0 -0.9 752168.0 68900.0 0.52 -0.2648 -0.2548 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D02 compound treatment 487234.0 -120000.0 -0.88 563056.0 -120000.0 -0.91 -1.2657 -0.9998 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D03 compound treatment 537326.0 -69800.0 -0.51 669622.0 -13700.0 -0.1 -0.4342 -0.8338 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D04 compound treatment 574540.0 -32600.0 -0.24 570236.0 -113000.0 -0.86 -0.7756 -0.8703 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D05 compound treatment 525056.0 -82000.0 -0.6 663690.0 -19600.0 -0.15 -0.5295 -0.8565 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D06 compound treatment 445859.0 -161000.0 -1.18 588026.0 -95300.0 -0.72 -1.3455 -0.9725 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D07 compound treatment 557634.0 -49500.0 -0.36 601318.0 -82000.0 -0.62 -0.6961 -0.9666 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D08 compound treatment 485581.0 -122000.0 -0.89 644339.0 -38900.0 -0.3 -0.8376 -0.8943 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D09 compound treatment 506217.0 -101000.0 -0.74 554358.0 -129000.0 -0.98 -1.2142 -0.9902 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D10 compound treatment 509174.0 -97900.0 -0.72 598202.0 -85100.0 -0.65 -0.9634 -0.9987 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D11 mock treatment 499516.0 -108000.0 -0.79 535776.0 -148000.0 -1.12 -1.3487 -0.985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D12 mock treatment 468384.0 -139000.0 -1.01 675597.0 -7680.0 -0.06 -0.7586 -0.7466 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D13 compound treatment 524798.0 -82300.0 -0.6 575178.0 -108000.0 -0.82 -1.0063 -0.9883 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D14 compound treatment 564651.0 -42400.0 -0.31 652036.0 -31200.0 -0.24 -0.3873 -0.9912 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D15 mock treatment 555564.0 -51500.0 -0.38 679131.0 -4150.0 -0.03 -0.2888 -0.7636 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D16 mock treatment 561970.0 -45100.0 -0.33 674342.0 -8940.0 -0.07 -0.2814 -0.8351 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D17 compound treatment 577667.0 -29400.0 -0.22 569054.0 -114000.0 -0.87 -0.7658 -0.8565 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D18 compound treatment 600822.0 -6280.0 -0.05 659987.0 -23300.0 -0.18 -0.1576 -0.862 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D19 compound treatment 589525.0 -17600.0 -0.13 625045.0 -58200.0 -0.44 -0.4037 -0.8763 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D20 compound treatment 515639.0 -91500.0 -0.67 593888.0 -89400.0 -0.68 -0.9532 -1.0 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D21 compound treatment 594111.0 -13000.0 -0.09 617668.0 -65600.0 -0.5 -0.4196 -0.827 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D22 compound treatment 566522.0 -40600.0 -0.3 603054.0 -80200.0 -0.61 -0.6408 -0.9453 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D23 compound treatment 559359.0 -47700.0 -0.35 619858.0 -63400.0 -0.48 -0.5876 -0.9875 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 D24 compound treatment 577576.0 -29500.0 -0.22 534104.0 -149000.0 -1.13 -0.954 -0.8269 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E01 mock treatment 479177.0 -128000.0 -0.94 642174.0 -41100.0 -0.31 -0.8823 -0.8946 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E02 mock treatment 581234.0 -25900.0 -0.19 632256.0 -51000.0 -0.39 -0.4078 -0.9456 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E03 compound treatment 593633.0 -13500.0 -0.1 651733.0 -31500.0 -0.24 -0.2391 -0.9228 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E04 compound treatment 505163.0 -102000.0 -0.75 630172.0 -53100.0 -0.4 -0.8124 -0.9584 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E05 compound treatment 580898.0 -26200.0 -0.19 623210.0 -60100.0 -0.46 -0.4582 -0.9257 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E06 compound treatment 575040.0 -32100.0 -0.23 671181.0 -12100.0 -0.09 -0.2308 -0.9164 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E07 compound treatment 542211.0 -64900.0 -0.47 621805.0 -61500.0 -0.47 -0.6658 -1.0 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E08 compound treatment 636248.0 29100.0 0.21 609672.0 -73600.0 -0.56 -0.2447 -0.4089 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E09 mock treatment 608900.0 1800.0 0.01 689960.0 6680.0 0.05 0.0452 0.8621 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E10 mock treatment 612305.0 5210.0 0.04 676836.0 -6450.0 -0.05 -0.0077 -0.1242 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E11 compound treatment 538026.0 -69100.0 -0.51 734724.0 51400.0 0.39 -0.0809 -0.1266 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E12 compound treatment 585081.0 -22000.0 -0.16 564833.0 -118000.0 -0.9 -0.7501 -0.8206 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E13 compound treatment 500874.0 -106000.0 -0.78 612129.0 -71200.0 -0.54 -0.9315 -0.9843 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E14 compound treatment 524977.0 -82100.0 -0.6 617950.0 -65300.0 -0.5 -0.7756 -0.9955 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E15 compound treatment 742203.0 135000.0 0.99 781133.0 97900.0 0.74 1.2243 0.9902 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E16 compound treatment 608494.0 1390.0 0.01 706843.0 23600.0 0.18 0.1338 0.7462 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E17 mock treatment 624284.0 17200.0 0.13 640474.0 -42800.0 -0.33 -0.1411 -0.4047 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E18 mock treatment 542629.0 -64500.0 -0.47 656481.0 -26800.0 -0.2 -0.4773 -0.9295 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E19 compound treatment 624455.0 17400.0 0.13 640541.0 -42700.0 -0.32 -0.1398 -0.4011 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E20 compound treatment 589855.0 -17200.0 -0.13 614908.0 -68400.0 -0.52 -0.4565 -0.854 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E21 compound treatment 628510.0 21400.0 0.16 683417.0 136.0 0.0 0.1114 0.7117 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E22 compound treatment 596582.0 -10500.0 -0.08 699538.0 16300.0 0.12 0.0329 0.2264 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E23 compound treatment 501171.0 -106000.0 -0.77 601345.0 -81900.0 -0.62 -0.9879 -0.9941 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 E24 compound treatment 552462.0 -54600.0 -0.4 545414.0 -138000.0 -1.05 -1.0231 -0.9127 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F01 mock treatment 543580.0 -63500.0 -0.46 610746.0 -72500.0 -0.55 -0.7181 -0.9964 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F02 mock treatment 512116.0 -95000.0 -0.69 588689.0 -94600.0 -0.72 -0.9993 -0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F03 compound treatment 479027.0 -128000.0 -0.94 611551.0 -71700.0 -0.54 -1.0476 -0.9668 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F04 compound treatment 570329.0 -36800.0 -0.27 717310.0 34000.0 0.26 -0.0074 -0.0197 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F05 compound treatment 446273.0 -161000.0 -1.18 735406.0 52100.0 0.4 -0.5517 -0.4445 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F06 compound treatment 493143.0 -114000.0 -0.83 698590.0 15300.0 0.12 -0.507 -0.6026 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F07 compound treatment 569843.0 -37300.0 -0.27 617857.0 -65400.0 -0.5 -0.5441 -0.96 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F08 compound treatment 482969.0 -124000.0 -0.91 682905.0 -376.0 0.0 -0.6439 -0.7093 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F09 mock treatment 583052.0 -24000.0 -0.18 697367.0 14100.0 0.11 -0.0487 -0.2365 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F10 mock treatment 527309.0 -79800.0 -0.58 660247.0 -23000.0 -0.17 -0.5363 -0.8804 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F11 compound treatment 550677.0 -56400.0 -0.41 655241.0 -28000.0 -0.21 -0.4424 -0.9527 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F12 compound treatment 589360.0 -17700.0 -0.13 573891.0 -109000.0 -0.83 -0.6793 -0.8077 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F13 compound treatment 562209.0 -44900.0 -0.33 554139.0 -129000.0 -0.98 -0.9259 -0.8949 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F14 compound treatment 698402.0 91300.0 0.67 699913.0 16600.0 0.13 0.5615 0.8262 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F15 compound treatment 514825.0 -92300.0 -0.67 706132.0 22900.0 0.17 -0.3544 -0.5086 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F16 compound treatment 533876.0 -73200.0 -0.54 668652.0 -14600.0 -0.11 -0.4572 -0.836 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F17 mock treatment 620480.0 13400.0 0.1 677590.0 -5690.0 -0.04 0.0386 0.361 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F18 mock treatment 629086.0 22000.0 0.16 689260.0 5980.0 0.05 0.1458 0.8727 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F19 compound treatment 617494.0 10400.0 0.08 710451.0 27200.0 0.21 0.1997 0.9079 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F20 compound treatment 615811.0 8710.0 0.06 675654.0 -7630.0 -0.06 0.0041 0.0474 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F21 compound treatment 684347.0 77200.0 0.56 679687.0 -3590.0 -0.03 0.3802 0.6721 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F22 compound treatment 571296.0 -35800.0 -0.26 621463.0 -61800.0 -0.47 -0.5172 -0.9619 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F23 compound treatment 630583.0 23500.0 0.17 613864.0 -69400.0 -0.53 -0.2515 -0.4534 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 F24 compound treatment 545847.0 -61300.0 -0.45 548057.0 -135000.0 -1.03 -1.0431 -0.9308 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G01 compound treatment 539325.0 -67800.0 -0.5 596791.0 -86500.0 -0.66 -0.8151 -0.9903 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G02 compound treatment 588867.0 -18200.0 -0.13 602973.0 -80300.0 -0.61 -0.5257 -0.8418 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G03 mock treatment 618886.0 11800.0 0.09 723599.0 40300.0 0.31 0.2775 0.8722 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G04 mock treatment 531959.0 -75100.0 -0.55 602670.0 -80600.0 -0.61 -0.8216 -0.9985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G05 compound treatment 556571.0 -50500.0 -0.37 662069.0 -21200.0 -0.16 -0.3752 -0.9308 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G06 compound treatment 564824.0 -42300.0 -0.31 625639.0 -57600.0 -0.44 -0.5283 -0.9855 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G07 compound treatment 647668.0 40600.0 0.3 695314.0 12000.0 0.09 0.2744 0.884 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G08 compound treatment 478812.0 -128000.0 -0.94 679464.0 -3820.0 -0.03 -0.6839 -0.7286 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G09 compound treatment 571715.0 -35400.0 -0.26 665253.0 -18000.0 -0.14 -0.2798 -0.9557 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G10 compound treatment 560816.0 -46300.0 -0.34 663218.0 -20100.0 -0.15 -0.3471 -0.9351 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G11 compound treatment 607430.0 331.0 0.0 733829.0 50500.0 0.38 0.2732 0.7115 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G12 compound treatment 504443.0 -103000.0 -0.75 656694.0 -26600.0 -0.2 -0.6737 -0.8665 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G13 compound treatment 607346.0 247.0 0.0 735430.0 52100.0 0.4 0.2814 0.7103 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G14 compound treatment 586885.0 -20200.0 -0.15 694081.0 10800.0 0.08 -0.0465 -0.2751 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G15 compound treatment 578783.0 -28300.0 -0.21 663782.0 -19500.0 -0.15 -0.2512 -0.9865 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G16 compound treatment 598816.0 -8280.0 -0.06 704747.0 21500.0 0.16 0.0725 0.4166 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G17 compound treatment 601276.0 -5820.0 -0.04 715753.0 32500.0 0.25 0.1443 0.5765 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G18 compound treatment 638392.0 31300.0 0.23 755207.0 71900.0 0.55 0.5482 0.9254 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G19 mock treatment 685393.0 78300.0 0.57 676361.0 -6920.0 -0.05 0.3677 0.6395 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G20 mock treatment 652705.0 45600.0 0.33 664129.0 -19200.0 -0.15 0.133 0.3654 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G21 compound treatment 651798.0 44700.0 0.33 716676.0 33400.0 0.25 0.4105 0.9921 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G22 compound treatment 612046.0 4950.0 0.04 661260.0 -22000.0 -0.17 -0.0927 -0.5417 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G23 compound treatment 636942.0 29800.0 0.22 628083.0 -55200.0 -0.42 -0.1422 -0.3008 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 G24 compound treatment 572700.0 -34400.0 -0.25 568928.0 -114000.0 -0.87 -0.7922 -0.8759 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H01 compound treatment 562578.0 -44500.0 -0.33 610175.0 -73100.0 -0.56 -0.6229 -0.9676 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H02 compound treatment 503726.0 -103000.0 -0.76 744272.0 61000.0 0.46 -0.2069 -0.2334 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H03 mock treatment 591133.0 -16000.0 -0.12 725979.0 42700.0 0.32 0.1468 0.4258 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H04 mock treatment 467213.0 -140000.0 -1.02 695724.0 12400.0 0.09 -0.6565 -0.639 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H05 compound treatment 509861.0 -97200.0 -0.71 785315.0 102000.0 0.78 0.0453 0.043 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H06 compound treatment 560265.0 -46800.0 -0.34 672324.0 -11000.0 -0.08 -0.301 -0.8541 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H07 compound treatment 682875.0 75800.0 0.55 601924.0 -81400.0 -0.62 -0.0452 -0.0544 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H08 compound treatment 536062.0 -71000.0 -0.52 680210.0 -3070.0 -0.02 -0.3838 -0.7381 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H09 compound treatment 629808.0 22700.0 0.17 758193.0 74900.0 0.57 0.5198 0.8769 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H10 compound treatment 487339.0 -120000.0 -0.88 746864.0 63600.0 0.48 -0.2777 -0.2777 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H11 compound treatment 596245.0 -10900.0 -0.08 662540.0 -20700.0 -0.16 -0.1675 -0.9496 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H12 compound treatment 478512.0 -129000.0 -0.94 647585.0 -35700.0 -0.27 -0.8567 -0.8753 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H13 compound treatment 526449.0 -80700.0 -0.59 698062.0 14800.0 0.11 -0.3377 -0.5624 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H14 compound treatment 534729.0 -72400.0 -0.53 684493.0 1210.0 0.01 -0.3677 -0.6947 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H15 compound treatment 555634.0 -51500.0 -0.38 723961.0 40700.0 0.31 -0.0476 -0.0978 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H16 compound treatment 568936.0 -38200.0 -0.28 773403.0 90100.0 0.68 0.2868 0.3879 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H17 compound treatment 607933.0 834.0 0.01 759962.0 76700.0 0.58 0.4162 0.7145 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H18 compound treatment 488223.0 -119000.0 -0.87 812879.0 130000.0 0.98 0.0814 0.062 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H19 mock treatment 627396.0 20300.0 0.15 661971.0 -21300.0 -0.16 -0.0095 -0.0433 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H20 mock treatment 586042.0 -21100.0 -0.15 755111.0 71800.0 0.55 0.277 0.4885 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H21 compound treatment 626864.0 19800.0 0.14 783704.0 100000.0 0.76 0.6417 0.8264 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H22 compound treatment 584245.0 -22900.0 -0.17 636040.0 -47200.0 -0.36 -0.3719 -0.9395 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H23 compound treatment 598760.0 -8340.0 -0.06 605612.0 -77700.0 -0.59 -0.4603 -0.7761 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 H24 compound treatment 564720.0 -42400.0 -0.31 598198.0 -85100.0 -0.65 -0.6762 -0.9433 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I01 compound treatment 608570.0 1470.0 0.01 644140.0 -39100.0 -0.3 -0.2027 -0.6811 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I02 compound treatment 545618.0 -61500.0 -0.45 553730.0 -130000.0 -0.98 -1.0138 -0.937 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I03 compound treatment 536030.0 -71100.0 -0.52 701547.0 18300.0 0.14 -0.2694 -0.5008 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I04 compound treatment 631054.0 24000.0 0.18 756551.0 73300.0 0.56 0.5175 0.8868 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I05 mock treatment 623339.0 16200.0 0.12 696375.0 13100.0 0.1 0.1543 0.9961 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I06 mock treatment 506381.0 -101000.0 -0.74 765140.0 81900.0 0.62 -0.0811 -0.0841 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I07 compound treatment 531089.0 -76000.0 -0.56 780862.0 97600.0 0.74 0.1311 0.1415 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I08 compound treatment 533283.0 -73800.0 -0.54 640694.0 -42600.0 -0.32 -0.6105 -0.97 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I09 compound treatment 632719.0 25600.0 0.19 639553.0 -43700.0 -0.33 -0.1024 -0.2685 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I10 compound treatment 516032.0 -91100.0 -0.67 602519.0 -80800.0 -0.61 -0.9048 -0.9992 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I11 compound treatment 618430.0 11300.0 0.08 825171.0 142000.0 1.08 0.8208 0.7592 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I12 compound treatment 530560.0 -76500.0 -0.56 655455.0 -27800.0 -0.21 -0.5453 -0.9113 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I13 compound treatment 702450.0 95400.0 0.7 765271.0 82000.0 0.62 0.9335 0.9984 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I14 compound treatment 650514.0 43400.0 0.32 709631.0 26300.0 0.2 0.366 0.9753 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I15 compound treatment 752854.0 146000.0 1.07 758442.0 75200.0 0.57 1.1575 0.9572 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I16 compound treatment 603234.0 -3870.0 -0.03 790298.0 107000.0 0.81 0.5549 0.6821 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I17 compound treatment 733971.0 127000.0 0.93 716874.0 33600.0 0.26 0.8365 0.8693 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I18 compound treatment 586201.0 -20900.0 -0.15 690836.0 7550.0 0.06 -0.0675 -0.4134 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I19 compound treatment 663856.0 56800.0 0.42 613000.0 -70300.0 -0.53 -0.084 -0.1243 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I20 compound treatment 643049.0 35900.0 0.26 767891.0 84600.0 0.64 0.6404 0.9222 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I21 mock treatment 648705.0 41600.0 0.3 756005.0 72700.0 0.55 0.6058 0.9605 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I22 mock treatment 626647.0 19500.0 0.14 629824.0 -53500.0 -0.41 -0.1861 -0.4322 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I23 compound treatment 623590.0 16500.0 0.12 676783.0 -6500.0 -0.05 0.0504 0.3865 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 I24 compound treatment 535271.0 -71800.0 -0.53 562737.0 -121000.0 -0.92 -1.019 -0.9652 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J01 compound treatment 734825.0 128000.0 0.93 662498.0 -20800.0 -0.16 0.5488 0.5794 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J02 compound treatment 580016.0 -27100.0 -0.2 676067.0 -7210.0 -0.05 -0.1788 -0.8701 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J03 compound treatment 548389.0 -58700.0 -0.43 649250.0 -34000.0 -0.26 -0.4864 -0.9705 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J04 compound treatment 579787.0 -27300.0 -0.2 829756.0 146000.0 1.11 0.6456 0.5711 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J05 mock treatment 479035.0 -128000.0 -0.94 702546.0 19300.0 0.15 -0.5588 -0.5895 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J06 mock treatment 576464.0 -30600.0 -0.22 652570.0 -30700.0 -0.23 -0.3234 -0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J07 compound treatment 582882.0 -24200.0 -0.18 748674.0 65400.0 0.5 0.226 0.4286 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J08 compound treatment 556107.0 -51000.0 -0.37 801454.0 118000.0 0.9 0.3711 0.3818 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J09 compound treatment 535577.0 -71500.0 -0.52 646501.0 -36800.0 -0.28 -0.5674 -0.9569 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J10 compound treatment 537630.0 -69500.0 -0.51 640424.0 -42900.0 -0.33 -0.5895 -0.9769 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J11 compound treatment 646331.0 39200.0 0.29 695380.0 12100.0 0.09 0.2679 0.8891 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J12 compound treatment 542290.0 -64800.0 -0.47 625424.0 -57900.0 -0.44 -0.6459 -0.9993 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J13 compound treatment 545949.0 -61200.0 -0.45 656910.0 -26400.0 -0.2 -0.4579 -0.9344 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J14 compound treatment 615454.0 8350.0 0.06 554340.0 -129000.0 -0.98 -0.6494 -0.6617 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J15 compound treatment 612668.0 5570.0 0.04 760201.0 76900.0 0.58 0.442 0.7546 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J16 compound treatment 569726.0 -37400.0 -0.27 722616.0 39300.0 0.3 0.018 0.0445 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J17 compound treatment 591311.0 -15800.0 -0.12 694627.0 11300.0 0.09 -0.0207 -0.1436 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J18 compound treatment 606000.0 -1100.0 -0.01 768318.0 85000.0 0.65 0.4511 0.6983 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J19 compound treatment 626060.0 19000.0 0.14 762897.0 79600.0 0.6 0.5257 0.8472 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J20 compound treatment 606158.0 -941.0 -0.01 761060.0 77800.0 0.59 0.4129 0.6988 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J21 mock treatment 713159.0 106000.0 0.78 739705.0 56400.0 0.43 0.8515 0.9609 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J22 mock treatment 632472.0 25400.0 0.19 760844.0 77600.0 0.59 0.5479 0.8868 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J23 compound treatment 587102.0 -20000.0 -0.15 660881.0 -22400.0 -0.17 -0.2237 -0.9972 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 J24 compound treatment 621519.0 14400.0 0.11 644942.0 -38300.0 -0.29 -0.1314 -0.4241 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K01 compound treatment 609899.0 2800.0 0.02 648555.0 -34700.0 -0.26 -0.1721 -0.6503 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K02 compound treatment 593169.0 -13900.0 -0.1 708958.0 25700.0 0.2 0.0659 0.2994 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K03 compound treatment 495455.0 -112000.0 -0.82 696597.0 13300.0 0.1 -0.5058 -0.6148 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K04 compound treatment 620448.0 13300.0 0.1 711967.0 28700.0 0.22 0.2231 0.9344 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K05 compound treatment 603130.0 -3970.0 -0.03 666141.0 -17100.0 -0.13 -0.1126 -0.844 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K06 compound treatment 480031.0 -127000.0 -0.93 676158.0 -7120.0 -0.05 -0.6954 -0.747 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K07 mock treatment 628590.0 21500.0 0.16 630526.0 -52800.0 -0.4 -0.1723 -0.4001 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K08 mock treatment 574078.0 -33000.0 -0.24 770036.0 86800.0 0.66 0.2953 0.4207 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K09 compound treatment 605601.0 -1500.0 -0.01 736543.0 53300.0 0.4 0.2784 0.6877 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K10 compound treatment 573619.0 -33500.0 -0.24 697448.0 14200.0 0.11 -0.097 -0.3628 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K11 compound treatment 605358.0 -1740.0 -0.01 861041.0 178000.0 1.35 0.9459 0.7004 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K12 compound treatment 529249.0 -77900.0 -0.57 628345.0 -54900.0 -0.42 -0.6977 -0.9883 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K13 compound treatment 737618.0 131000.0 0.95 869318.0 186000.0 1.41 1.6743 0.9817 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K14 compound treatment 558113.0 -49000.0 -0.36 783028.0 99700.0 0.76 0.2825 0.337 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K15 mock treatment 738589.0 131000.0 0.96 781624.0 98300.0 0.75 1.2082 0.9922 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K16 mock treatment 630902.0 23800.0 0.17 739867.0 56600.0 0.43 0.4271 0.9208 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K17 compound treatment 645850.0 38800.0 0.28 697268.0 14000.0 0.11 0.2755 0.9103 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K18 compound treatment 566371.0 -40700.0 -0.3 771512.0 88200.0 0.67 0.2633 0.359 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K19 compound treatment 568366.0 -38700.0 -0.28 707158.0 23900.0 0.18 -0.072 -0.2142 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K20 compound treatment 650784.0 43700.0 0.32 744740.0 61500.0 0.47 0.556 0.9829 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K21 compound treatment 661436.0 54300.0 0.4 679167.0 -4110.0 -0.03 0.2589 0.6495 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K22 compound treatment 640975.0 33900.0 0.25 731162.0 47900.0 0.36 0.4324 0.9825 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K23 mock treatment 657354.0 50300.0 0.37 637509.0 -45800.0 -0.35 0.014 0.0277 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 K24 mock treatment 600916.0 -6180.0 -0.05 606688.0 -76600.0 -0.58 -0.4434 -0.7598 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L01 compound treatment 650348.0 43200.0 0.32 619288.0 -64000.0 -0.49 -0.1201 -0.2071 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L02 compound treatment 580174.0 -26900.0 -0.2 615919.0 -67400.0 -0.51 -0.5011 -0.9139 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L03 compound treatment 541713.0 -65400.0 -0.48 675843.0 -7440.0 -0.06 -0.3781 -0.7852 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L04 compound treatment 640458.0 33400.0 0.24 706041.0 22800.0 0.17 0.2948 0.9858 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L05 compound treatment 600324.0 -6780.0 -0.05 688603.0 5320.0 0.04 -0.0064 -0.1008 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L06 compound treatment 567256.0 -39800.0 -0.29 693190.0 9910.0 0.08 -0.1528 -0.5078 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L07 mock treatment 595334.0 -11800.0 -0.09 699279.0 16000.0 0.12 0.0251 0.1685 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L08 mock treatment 546560.0 -60500.0 -0.44 706791.0 23500.0 0.18 -0.1868 -0.3912 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L09 compound treatment 588235.0 -18900.0 -0.14 581891.0 -101000.0 -0.77 -0.6422 -0.8207 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L10 compound treatment 660709.0 53600.0 0.39 695727.0 12400.0 0.09 0.3441 0.8532 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L11 compound treatment 707681.0 101000.0 0.74 707342.0 24100.0 0.18 0.6494 0.8568 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L12 compound treatment 566771.0 -40300.0 -0.29 586793.0 -96500.0 -0.73 -0.7269 -0.9199 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L13 compound treatment 708656.0 102000.0 0.74 755657.0 72400.0 0.55 0.9139 0.989 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L14 compound treatment 578253.0 -28800.0 -0.21 655597.0 -27700.0 -0.21 -0.2979 -1.0 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L15 mock treatment 613032.0 5930.0 0.04 749750.0 66500.0 0.5 0.3877 0.765 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L16 mock treatment 648444.0 41300.0 0.3 724770.0 41500.0 0.32 0.4367 0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L17 compound treatment 584258.0 -22800.0 -0.17 754815.0 71500.0 0.54 0.2661 0.4681 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L18 compound treatment 567577.0 -39500.0 -0.29 737663.0 54400.0 0.41 0.0877 0.174 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L19 compound treatment 657595.0 50500.0 0.37 672010.0 -11300.0 -0.09 0.2006 0.5291 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L20 compound treatment 575813.0 -31300.0 -0.23 696875.0 13600.0 0.1 -0.0888 -0.3536 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L21 compound treatment 778409.0 171000.0 1.25 739806.0 56500.0 0.43 1.1895 0.8982 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L22 compound treatment 635867.0 28800.0 0.21 743690.0 60400.0 0.46 0.4733 0.9375 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L23 mock treatment 681364.0 74300.0 0.54 703164.0 19900.0 0.15 0.4908 0.8707 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 L24 mock treatment 602469.0 -4630.0 -0.03 737307.0 54000.0 0.41 0.2663 0.6466 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M01 compound treatment 639713.0 32600.0 0.24 692603.0 9320.0 0.07 0.2187 0.8791 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M02 compound treatment 608949.0 1850.0 0.01 629771.0 -53500.0 -0.41 -0.2779 -0.6832 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M03 compound treatment 599703.0 -7400.0 -0.05 666252.0 -17000.0 -0.13 -0.1297 -0.9251 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M04 compound treatment 636052.0 29000.0 0.21 708204.0 24900.0 0.19 0.2836 0.9984 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M05 compound treatment 656899.0 49800.0 0.36 730954.0 47700.0 0.36 0.5136 1.0 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M06 compound treatment 598978.0 -8120.0 -0.06 718179.0 34900.0 0.27 0.1455 0.5354 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M07 compound treatment 700996.0 93900.0 0.69 803855.0 121000.0 0.92 1.1332 0.9899 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M08 compound treatment 554247.0 -52900.0 -0.39 665890.0 -17400.0 -0.13 -0.3667 -0.8978 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M09 mock treatment 636961.0 29900.0 0.22 695430.0 12100.0 0.09 0.2197 0.9266 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M10 mock treatment 690574.0 83500.0 0.61 154438.0 -529000.0 -4.02 -2.4091 -0.5929 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M11 compound treatment 680042.0 72900.0 0.53 784450.0 101000.0 0.77 0.9207 0.9841 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M12 compound treatment 625316.0 18200.0 0.13 665843.0 -17400.0 -0.13 5.0E-4 0.0028 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M13 mock treatment 707042.0 99900.0 0.73 727073.0 43800.0 0.33 0.7521 0.9365 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M14 mock treatment 569941.0 -37200.0 -0.27 746531.0 63200.0 0.48 0.1476 0.2674 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M15 compound treatment 867924.0 261000.0 1.91 768111.0 84800.0 0.64 1.8044 0.8962 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M16 compound treatment 615349.0 8250.0 0.06 818691.0 135000.0 1.03 0.77 0.7473 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M17 compound treatment 688405.0 81300.0 0.59 728345.0 45100.0 0.34 0.6625 0.9656 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M18 compound treatment 698859.0 91800.0 0.67 724838.0 41600.0 0.32 0.6977 0.9408 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M19 compound treatment 708197.0 101000.0 0.74 582195.0 -101000.0 -0.77 -0.0202 -0.019 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M20 compound treatment 677862.0 70800.0 0.52 795958.0 113000.0 0.86 0.9712 0.9709 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M21 compound treatment 679195.0 72100.0 0.53 725726.0 42400.0 0.32 0.6008 0.9722 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M22 compound treatment 635017.0 27900.0 0.2 710149.0 26900.0 0.2 0.2887 1.0 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M23 compound treatment 665985.0 58900.0 0.43 701520.0 18200.0 0.14 0.4025 0.8897 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 M24 compound treatment 678389.0 71300.0 0.52 609216.0 -74100.0 -0.56 -0.0292 -0.0381 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N01 compound treatment 664576.0 57500.0 0.42 719277.0 36000.0 0.27 0.4906 0.9783 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N02 compound treatment 569650.0 -37400.0 -0.27 718883.0 35600.0 0.27 -0.0024 -0.0063 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N03 compound treatment 664612.0 57500.0 0.42 775026.0 91700.0 0.7 0.7902 0.9708 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N04 compound treatment 586685.0 -20400.0 -0.15 832410.0 149000.0 1.13 0.6955 0.6087 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N05 compound treatment 587479.0 -19600.0 -0.14 676228.0 -7050.0 -0.05 -0.1393 -0.9098 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N06 compound treatment 578422.0 -28700.0 -0.21 781733.0 98500.0 0.75 0.3806 0.4899 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N07 compound treatment 688188.0 81100.0 0.59 682380.0 -901.0 -0.01 0.4145 0.6989 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N08 compound treatment 521726.0 -85400.0 -0.62 723672.0 40400.0 0.31 -0.2245 -0.3227 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N09 mock treatment 692646.0 85500.0 0.63 880855.0 198000.0 1.5 1.5037 0.9247 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N10 mock treatment 666228.0 59100.0 0.43 762239.0 79000.0 0.6 0.7299 0.9871 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N11 compound treatment 649578.0 42500.0 0.31 628020.0 -55300.0 -0.42 -0.0772 -0.1478 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N12 compound treatment 559989.0 -47100.0 -0.34 687247.0 3970.0 0.03 -0.2223 -0.6428 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N13 mock treatment 719155.0 112000.0 0.82 669952.0 -13300.0 -0.1 0.5079 0.6151 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N14 mock treatment 572252.0 -34800.0 -0.25 757356.0 74100.0 0.56 0.2177 0.3524 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N15 compound treatment 727255.0 120000.0 0.88 836812.0 154000.0 1.17 1.4461 0.9903 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N16 compound treatment 694277.0 87200.0 0.64 705424.0 22100.0 0.17 0.5698 0.8641 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N17 compound treatment 763023.0 156000.0 1.14 659493.0 -23800.0 -0.18 0.6785 0.5877 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N18 compound treatment 734409.0 127000.0 0.93 781026.0 97700.0 0.74 1.1834 0.9937 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N19 compound treatment 766469.0 159000.0 1.17 726736.0 43500.0 0.33 1.0576 0.873 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N20 compound treatment 701191.0 94100.0 0.69 806148.0 123000.0 0.93 1.1466 0.9888 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N21 compound treatment 679504.0 72400.0 0.53 765144.0 81900.0 0.62 0.8142 0.9968 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N22 compound treatment 642528.0 35400.0 0.26 689138.0 5860.0 0.04 0.2147 0.8166 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N23 compound treatment 679044.0 71900.0 0.53 739420.0 56100.0 0.43 0.6736 0.9946 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 N24 compound treatment 658214.0 51100.0 0.37 755661.0 72400.0 0.55 0.6531 0.9823 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O01 compound treatment 673093.0 66000.0 0.48 660318.0 -23000.0 -0.17 0.2179 0.4246 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O02 compound treatment 586072.0 -21000.0 -0.15 689992.0 6710.0 0.05 -0.0727 -0.4487 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O03 compound treatment 597242.0 -9860.0 -0.07 762489.0 79200.0 0.6 0.3745 0.618 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O04 compound treatment 666904.0 59800.0 0.44 703396.0 20100.0 0.15 0.4173 0.9008 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O05 compound treatment 707436.0 100000.0 0.73 713249.0 30000.0 0.23 0.6798 0.8849 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O06 compound treatment 651723.0 44600.0 0.33 719763.0 36500.0 0.28 0.4267 0.9967 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O07 compound treatment 638926.0 31800.0 0.23 722837.0 39600.0 0.3 0.3771 0.992 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O08 compound treatment 689352.0 82300.0 0.6 707788.0 24500.0 0.19 0.557 0.8846 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O09 compound treatment 754095.0 147000.0 1.07 731778.0 48500.0 0.37 1.0206 0.8982 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O10 compound treatment 698442.0 91300.0 0.67 717834.0 34600.0 0.26 0.658 0.9167 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O11 mock treatment 765650.0 159000.0 1.16 754391.0 71100.0 0.54 1.2019 0.9396 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O12 mock treatment 742535.0 135000.0 0.99 709053.0 25800.0 0.2 0.8388 0.8308 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O13 compound treatment 862580.0 255000.0 1.87 769126.0 85800.0 0.65 1.7823 0.9006 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O14 compound treatment 733716.0 127000.0 0.93 797685.0 114000.0 0.87 1.2693 0.9995 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O15 compound treatment 719835.0 113000.0 0.82 742761.0 59500.0 0.45 0.9025 0.9599 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O16 compound treatment 890517.0 283000.0 2.07 690102.0 6820.0 0.05 1.5022 0.7246 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O17 compound treatment 716865.0 110000.0 0.8 659162.0 -24100.0 -0.18 0.4381 0.532 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O18 compound treatment 708960.0 102000.0 0.74 688317.0 5040.0 0.04 0.5538 0.7424 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O19 compound treatment 683191.0 76100.0 0.56 616278.0 -67000.0 -0.51 0.0336 0.0445 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O20 compound treatment 679877.0 72800.0 0.53 661500.0 -21800.0 -0.17 0.2593 0.4653 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O21 compound treatment 628537.0 21400.0 0.16 802685.0 119000.0 0.91 0.7523 0.8172 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O22 compound treatment 640433.0 33300.0 0.24 760099.0 76800.0 0.58 0.585 0.925 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O23 compound treatment 676164.0 69100.0 0.51 669935.0 -13300.0 -0.1 0.2855 0.5541 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 O24 compound treatment 591584.0 -15500.0 -0.11 684289.0 1010.0 0.01 -0.0748 -0.6579 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P01 compound treatment 699989.0 92900.0 0.68 888878.0 206000.0 1.56 1.5848 0.9305 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P02 compound treatment 644454.0 37400.0 0.27 740808.0 57500.0 0.44 0.5022 0.9744 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P03 compound treatment 643264.0 36200.0 0.26 786290.0 103000.0 0.78 0.7403 0.8963 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P04 compound treatment 706855.0 99800.0 0.73 777967.0 94700.0 0.72 1.0245 1.0 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P05 compound treatment 712354.0 105000.0 0.77 764380.0 81100.0 0.62 0.9799 0.9939 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P06 compound treatment 701644.0 94500.0 0.69 673319.0 -9960.0 -0.08 0.4354 0.626 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P07 compound treatment 715723.0 109000.0 0.79 764296.0 81000.0 0.62 0.9969 0.992 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P08 compound treatment 634744.0 27600.0 0.2 733590.0 50300.0 0.38 0.4132 0.9557 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P09 compound treatment 742608.0 136000.0 0.99 794682.0 111000.0 0.85 1.2992 0.9969 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P10 compound treatment 731739.0 125000.0 0.91 707181.0 23900.0 0.18 0.7729 0.8316 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P11 mock treatment 728868.0 122000.0 0.89 729633.0 46400.0 0.35 0.8787 0.9176 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P12 mock treatment 760566.0 153000.0 1.12 700773.0 17500.0 0.13 0.8876 0.7853 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P13 compound treatment 799610.0 193000.0 1.41 850414.0 167000.0 1.27 1.8933 0.9987 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P14 compound treatment 862003.0 255000.0 1.86 731816.0 48500.0 0.37 1.5789 0.8309 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P15 compound treatment 821564.0 214000.0 1.57 710088.0 26800.0 0.2 1.253 0.7923 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P16 compound treatment 769797.0 163000.0 1.19 814888.0 132000.0 1.0 1.5483 0.9963 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P17 compound treatment 651511.0 44400.0 0.32 711895.0 28600.0 0.22 0.3834 0.9809 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P18 compound treatment 762604.0 156000.0 1.14 657197.0 -26100.0 -0.2 0.664 0.5752 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P19 compound treatment 821159.0 214000.0 1.57 753692.0 70400.0 0.53 1.4852 0.8978 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P20 compound treatment 759534.0 152000.0 1.11 711225.0 27900.0 0.21 0.9384 0.8269 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P21 compound treatment 750520.0 143000.0 1.05 814013.0 131000.0 0.99 1.4439 0.9996 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P22 compound treatment 746394.0 139000.0 1.02 759867.0 76600.0 0.58 1.1317 0.9647 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P23 compound treatment 780372.0 173000.0 1.27 753395.0 70100.0 0.53 1.2727 0.9259 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2100 P24 compound treatment 722592.0 115000.0 0.84 723147.0 39900.0 0.3 0.8114 0.9043 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A01 compound treatment 527313.0 -126000.0 -0.92 574250.0 -66800.0 -0.51 -1.0123 -0.96 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A02 compound treatment 530608.0 -123000.0 -0.9 565961.0 -75000.0 -0.57 -1.0398 -0.9757 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A03 compound treatment 537935.0 -116000.0 -0.85 618213.0 -22800.0 -0.17 -0.7212 -0.8344 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A04 compound treatment 714211.0 60500.0 0.44 637070.0 -3930.0 -0.03 0.2917 0.6579 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A05 compound treatment 557992.0 -95700.0 -0.7 494217.0 -147000.0 -1.12 -1.2835 -0.9749 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A06 compound treatment 552981.0 -101000.0 -0.74 569740.0 -71300.0 -0.54 -0.9038 -0.9885 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A07 compound treatment 600405.0 -53300.0 -0.39 573267.0 -67700.0 -0.51 -0.6396 -0.9906 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A08 compound treatment 552924.0 -101000.0 -0.74 532657.0 -108000.0 -0.82 -1.1033 -0.9985 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A09 compound treatment 622262.0 -31500.0 -0.23 580037.0 -61000.0 -0.46 -0.4902 -0.9479 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A10 compound treatment 611664.0 -42100.0 -0.31 613459.0 -27500.0 -0.21 -0.3655 -0.9824 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A11 compound treatment 624089.0 -29600.0 -0.22 661226.0 20200.0 0.15 -0.0446 -0.1679 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A12 compound treatment 563046.0 -90700.0 -0.66 756147.0 115000.0 0.87 0.1496 0.1363 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A13 mock treatment 599717.0 -54000.0 -0.39 623247.0 -17800.0 -0.13 -0.3747 -0.8977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A14 mock treatment 602603.0 -51100.0 -0.37 535457.0 -106000.0 -0.8 -0.8313 -0.9397 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A15 compound treatment 697228.0 43500.0 0.32 750184.0 109000.0 0.83 0.8115 0.9134 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A16 compound treatment 677653.0 23900.0 0.17 641556.0 556.0 0.0 0.1267 0.724 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A17 compound treatment 642590.0 -11100.0 -0.08 652987.0 12000.0 0.09 0.0068 0.0556 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A18 compound treatment 682118.0 28400.0 0.21 583951.0 -57000.0 -0.43 -0.1596 -0.3322 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A19 compound treatment 527410.0 -126000.0 -0.92 628290.0 -12700.0 -0.1 -0.7215 -0.7768 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A20 compound treatment 563624.0 -90100.0 -0.66 631426.0 -9570.0 -0.07 -0.5174 -0.7804 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A21 compound treatment 596009.0 -57700.0 -0.42 651201.0 10200.0 0.08 -0.2437 -0.5678 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A22 compound treatment 642574.0 -11200.0 -0.08 654040.0 13000.0 0.1 0.0124 0.0964 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A23 compound treatment 562872.0 -90900.0 -0.66 623135.0 -17900.0 -0.14 -0.5658 -0.8343 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 A24 compound treatment 549778.0 -104000.0 -0.76 595617.0 -45400.0 -0.34 -0.7813 -0.936 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B01 compound treatment 597719.0 -56000.0 -0.41 697410.0 56400.0 0.43 0.0134 0.0226 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B02 compound treatment 557645.0 -96100.0 -0.7 574926.0 -66100.0 -0.5 -0.8518 -0.9864 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B03 compound treatment 563671.0 -90100.0 -0.66 574642.0 -66400.0 -0.5 -0.8222 -0.9913 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B04 compound treatment 663731.0 10000.0 0.07 745498.0 104000.0 0.79 0.6131 0.769 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B05 compound treatment 685062.0 31300.0 0.23 601353.0 -39600.0 -0.3 -0.0509 -0.1346 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B06 compound treatment 595373.0 -58400.0 -0.43 526767.0 -114000.0 -0.87 -0.9154 -0.9466 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B07 compound treatment 590266.0 -63500.0 -0.46 578454.0 -62500.0 -0.48 -0.6642 -0.9999 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B08 compound treatment 617795.0 -35900.0 -0.26 684087.0 43100.0 0.33 0.0456 0.1087 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B09 compound treatment 499327.0 -154000.0 -1.13 675208.0 34200.0 0.26 -0.6147 -0.5305 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B10 compound treatment 568540.0 -85200.0 -0.62 490086.0 -151000.0 -1.15 -1.2512 -0.9589 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B11 compound treatment 525609.0 -128000.0 -0.94 658384.0 17400.0 0.13 -0.5691 -0.6015 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B12 compound treatment 496335.0 -157000.0 -1.15 635899.0 -5100.0 -0.04 -0.8413 -0.7305 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B13 mock treatment 489687.0 -164000.0 -1.2 582925.0 -58100.0 -0.44 -1.1602 -0.9077 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B14 mock treatment 649424.0 -4300.0 -0.03 614900.0 -26100.0 -0.2 -0.1625 -0.8092 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B15 compound treatment 688321.0 34600.0 0.25 698515.0 57500.0 0.44 0.4878 0.9662 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B16 compound treatment 564824.0 -88900.0 -0.65 639262.0 -1740.0 -0.01 -0.4691 -0.7213 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B17 compound treatment 634827.0 -18900.0 -0.14 674038.0 33000.0 0.25 0.0797 0.2783 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B18 compound treatment 630744.0 -23000.0 -0.17 563447.0 -77600.0 -0.59 -0.5355 -0.874 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B19 compound treatment 654907.0 1180.0 0.01 702561.0 61600.0 0.47 0.3368 0.72 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B20 compound treatment 617485.0 -36200.0 -0.27 675103.0 34100.0 0.26 -0.0042 -0.0114 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B21 compound treatment 581421.0 -72300.0 -0.53 663158.0 22200.0 0.17 -0.2549 -0.4593 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B22 compound treatment 635490.0 -18200.0 -0.13 636884.0 -4120.0 -0.03 -0.1164 -0.8498 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B23 compound treatment 596147.0 -57600.0 -0.42 747975.0 107000.0 0.81 0.2769 0.3025 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 B24 compound treatment 600340.0 -53400.0 -0.39 717320.0 76300.0 0.58 0.1339 0.1915 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C01 compound treatment 515354.0 -138000.0 -1.01 540893.0 -100000.0 -0.76 -1.2533 -0.9901 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C02 compound treatment 450671.0 -203000.0 -1.48 457690.0 -183000.0 -1.39 -2.0347 -0.9995 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C03 compound treatment 472804.0 -181000.0 -1.32 623559.0 -17400.0 -0.13 -1.0293 -0.774 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C04 compound treatment 625077.0 -28700.0 -0.21 565145.0 -75900.0 -0.58 -0.5556 -0.9062 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C05 compound treatment 501436.0 -152000.0 -1.11 674299.0 33300.0 0.25 -0.6087 -0.5329 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C06 compound treatment 464168.0 -190000.0 -1.39 434954.0 -206000.0 -1.57 -2.0871 -0.9982 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C07 compound treatment 502353.0 -151000.0 -1.11 641230.0 230.0 0.0 -0.7815 -0.706 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C08 compound treatment 580208.0 -73500.0 -0.54 560812.0 -80200.0 -0.61 -0.8109 -0.9981 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C09 compound treatment 577508.0 -76200.0 -0.56 613556.0 -27400.0 -0.21 -0.5416 -0.91 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C10 compound treatment 582246.0 -71500.0 -0.52 670925.0 29900.0 0.23 -0.2089 -0.3665 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C11 mock treatment 622652.0 -31100.0 -0.23 623486.0 -17500.0 -0.13 -0.2548 -0.9675 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C12 mock treatment 607887.0 -45800.0 -0.34 679264.0 38300.0 0.29 -0.0315 -0.071 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C13 compound treatment 567826.0 -85900.0 -0.63 656578.0 15600.0 0.12 -0.3605 -0.564 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C14 compound treatment 638313.0 -15400.0 -0.11 673620.0 32600.0 0.25 0.0955 0.3508 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C15 mock treatment 654092.0 364.0 0.0 732124.0 91100.0 0.69 0.4914 0.7098 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C16 mock treatment 593773.0 -60000.0 -0.44 673136.0 32100.0 0.24 -0.1374 -0.2738 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C17 compound treatment 518877.0 -135000.0 -0.99 569433.0 -71600.0 -0.54 -1.0818 -0.9606 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C18 compound treatment 650487.0 -3240.0 -0.02 653598.0 12600.0 0.1 0.0509 0.5164 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C19 compound treatment 545879.0 -108000.0 -0.79 701816.0 60800.0 0.46 -0.231 -0.2527 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C20 compound treatment 578908.0 -74800.0 -0.55 598062.0 -42900.0 -0.33 -0.6176 -0.9695 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C21 compound treatment 609578.0 -44200.0 -0.32 669489.0 28500.0 0.22 -0.0753 -0.1937 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C22 compound treatment 624687.0 -29000.0 -0.21 690033.0 49000.0 0.37 0.1132 0.264 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C23 compound treatment 573603.0 -80100.0 -0.59 646577.0 5580.0 0.04 -0.3844 -0.6543 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 C24 compound treatment 579308.0 -74400.0 -0.54 590153.0 -50800.0 -0.39 -0.658 -0.9859 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D01 compound treatment 581409.0 -72300.0 -0.53 627462.0 -13500.0 -0.1 -0.4467 -0.8291 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D02 compound treatment 505202.0 -149000.0 -1.09 615561.0 -25400.0 -0.19 -0.9047 -0.82 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D03 compound treatment 611627.0 -42100.0 -0.31 605882.0 -35100.0 -0.27 -0.4064 -0.9975 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D04 compound treatment 616019.0 -37700.0 -0.28 589056.0 -51900.0 -0.39 -0.474 -0.9846 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D05 compound treatment 590098.0 -63600.0 -0.47 591868.0 -49100.0 -0.37 -0.593 -0.994 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D06 compound treatment 552675.0 -101000.0 -0.74 557785.0 -83200.0 -0.63 -0.9696 -0.997 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D07 compound treatment 617294.0 -36400.0 -0.27 641476.0 476.0 0.0 -0.1859 -0.6975 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D08 compound treatment 659841.0 6110.0 0.04 688832.0 47800.0 0.36 0.2885 0.7882 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D09 compound treatment 556597.0 -97100.0 -0.71 678070.0 37100.0 0.28 -0.3032 -0.3967 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D10 compound treatment 589098.0 -64600.0 -0.47 522721.0 -118000.0 -0.9 -0.9696 -0.955 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D11 mock treatment 672621.0 18900.0 0.14 617559.0 -23400.0 -0.18 -0.0282 -0.1252 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D12 mock treatment 613989.0 -39700.0 -0.29 579067.0 -61900.0 -0.47 -0.5382 -0.9732 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D13 compound treatment 635091.0 -18600.0 -0.14 678809.0 37800.0 0.29 0.1067 0.3357 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D14 compound treatment 671600.0 17900.0 0.13 706075.0 65100.0 0.49 0.442 0.8644 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D15 mock treatment 672584.0 18900.0 0.14 626487.0 -14500.0 -0.11 0.0195 0.1107 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D16 mock treatment 549463.0 -104000.0 -0.76 500670.0 -140000.0 -1.07 -1.293 -0.9865 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D17 compound treatment 697883.0 44200.0 0.32 691147.0 50100.0 0.38 0.4977 0.9966 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D18 compound treatment 650663.0 -3070.0 -0.02 663983.0 23000.0 0.17 0.1076 0.6113 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D19 compound treatment 629410.0 -24300.0 -0.18 655986.0 15000.0 0.11 -0.0453 -0.2143 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D20 compound treatment 694110.0 40400.0 0.3 627448.0 -13600.0 -0.1 0.136 0.4349 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D21 compound treatment 659424.0 5700.0 0.04 564649.0 -76400.0 -0.58 -0.3807 -0.6546 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D22 compound treatment 720804.0 67100.0 0.49 735932.0 94900.0 0.72 0.8568 0.9824 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D23 compound treatment 642930.0 -10800.0 -0.08 743635.0 103000.0 0.78 0.4955 0.6323 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 D24 compound treatment 570122.0 -83600.0 -0.61 632985.0 -8020.0 -0.06 -0.4754 -0.7737 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E01 mock treatment 524835.0 -129000.0 -0.94 581548.0 -59500.0 -0.45 -0.9859 -0.9432 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E02 mock treatment 544391.0 -109000.0 -0.8 591216.0 -49800.0 -0.38 -0.8328 -0.9416 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E03 compound treatment 638484.0 -15200.0 -0.11 621180.0 -19800.0 -0.15 -0.1853 -0.9891 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E04 compound treatment 592895.0 -60800.0 -0.44 641808.0 808.0 0.01 -0.3102 -0.6973 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E05 compound treatment 616373.0 -37400.0 -0.27 663539.0 22500.0 0.17 -0.0721 -0.2236 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E06 compound treatment 608733.0 -45000.0 -0.33 579721.0 -61300.0 -0.47 -0.5619 -0.9856 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E07 compound treatment 592017.0 -61700.0 -0.45 560523.0 -80500.0 -0.61 -0.7514 -0.9888 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E08 compound treatment 609253.0 -44500.0 -0.33 569893.0 -71100.0 -0.54 -0.612 -0.9705 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E09 mock treatment 654689.0 961.0 0.01 629091.0 -11900.0 -0.09 -0.059 -0.6502 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E10 mock treatment 679264.0 25500.0 0.19 569172.0 -71800.0 -0.55 -0.2538 -0.4401 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E11 compound treatment 576948.0 -76800.0 -0.56 565434.0 -75600.0 -0.57 -0.803 -0.9999 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E12 compound treatment 517199.0 -137000.0 -1.0 535931.0 -105000.0 -0.8 -1.2704 -0.9938 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E13 compound treatment 622328.0 -31400.0 -0.23 570222.0 -70800.0 -0.54 -0.5426 -0.928 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E14 compound treatment 548305.0 -105000.0 -0.77 489427.0 -152000.0 -1.15 -1.3594 -0.981 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E15 compound treatment 584005.0 -69700.0 -0.51 627352.0 -13600.0 -0.1 -0.4339 -0.8338 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E16 compound treatment 719075.0 65300.0 0.48 491854.0 -149000.0 -1.13 -0.4633 -0.3767 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E17 mock treatment 673411.0 19700.0 0.14 678601.0 37600.0 0.29 0.3038 0.9497 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E18 mock treatment 653710.0 -18.2 0.0 691068.0 50100.0 0.38 0.2689 0.7069 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E19 compound treatment 619442.0 -34300.0 -0.25 713159.0 72200.0 0.55 0.2103 0.3489 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E20 compound treatment 677394.0 23700.0 0.17 705712.0 64700.0 0.49 0.47 0.9018 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E21 compound treatment 706620.0 52900.0 0.39 741474.0 100000.0 0.76 0.8132 0.9504 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E22 compound treatment 655555.0 1830.0 0.01 683348.0 42300.0 0.32 0.2369 0.7358 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E23 compound treatment 641484.0 -12200.0 -0.09 675298.0 34300.0 0.26 0.1209 0.4389 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 E24 compound treatment 654466.0 738.0 0.01 611769.0 -29200.0 -0.22 -0.1532 -0.6897 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F01 mock treatment 615996.0 -37700.0 -0.28 588517.0 -52500.0 -0.4 -0.477 -0.9838 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F02 mock treatment 659906.0 6180.0 0.05 635844.0 -5160.0 -0.04 0.0042 0.071 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F03 compound treatment 609466.0 -44300.0 -0.32 590318.0 -50700.0 -0.39 -0.5011 -0.9963 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F04 compound treatment 480918.0 -173000.0 -1.26 535095.0 -106000.0 -0.8 -1.4625 -0.9762 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F05 compound treatment 630059.0 -23700.0 -0.17 618827.0 -22200.0 -0.17 -0.2415 -0.9999 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F06 compound treatment 494108.0 -160000.0 -1.17 572178.0 -68800.0 -0.52 -1.1951 -0.9344 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F07 compound treatment 513225.0 -141000.0 -1.03 614414.0 -26600.0 -0.2 -0.8694 -0.8302 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F08 compound treatment 510610.0 -143000.0 -1.05 513754.0 -127000.0 -0.97 -1.4236 -0.9992 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F09 mock treatment 672487.0 18800.0 0.14 555432.0 -85600.0 -0.65 -0.3626 -0.5459 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F10 mock treatment 647701.0 -6030.0 -0.04 602906.0 -38100.0 -0.29 -0.2358 -0.8055 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F11 compound treatment 596012.0 -57700.0 -0.42 562030.0 -79000.0 -0.6 -0.7227 -0.9852 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F12 compound treatment 556227.0 -97500.0 -0.71 573001.0 -68000.0 -0.52 -0.8695 -0.9875 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F13 compound treatment 538174.0 -116000.0 -0.85 641132.0 132.0 0.0 -0.5968 -0.7063 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F14 compound treatment 628169.0 -25600.0 -0.19 572636.0 -68400.0 -0.52 -0.4994 -0.9048 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F15 compound treatment 632771.0 -21000.0 -0.15 500228.0 -141000.0 -1.07 -0.8646 -0.8003 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F16 compound treatment 665811.0 12100.0 0.09 700929.0 59900.0 0.46 0.3844 0.8289 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F17 mock treatment 694424.0 40700.0 0.3 510841.0 -130000.0 -0.99 -0.4887 -0.4733 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F18 mock treatment 596153.0 -57600.0 -0.42 559184.0 -81800.0 -0.62 -0.7372 -0.982 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F19 compound treatment 682682.0 29000.0 0.21 633404.0 -7600.0 -0.06 0.1089 0.4963 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F20 compound treatment 717436.0 63700.0 0.47 731625.0 90600.0 0.69 0.8163 0.9819 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F21 compound treatment 693044.0 39300.0 0.29 706705.0 65700.0 0.5 0.5563 0.9657 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F22 compound treatment 576940.0 -76800.0 -0.56 694073.0 53100.0 0.4 -0.112 -0.162 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F23 compound treatment 609914.0 -43800.0 -0.32 711507.0 70500.0 0.54 0.1522 0.2438 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 F24 compound treatment 576554.0 -77200.0 -0.56 641952.0 952.0 0.01 -0.394 -0.698 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G01 compound treatment 492403.0 -161000.0 -1.18 544774.0 -96200.0 -0.73 -1.3511 -0.9735 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G02 compound treatment 458660.0 -195000.0 -1.43 556519.0 -84500.0 -0.64 -1.4625 -0.935 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G03 mock treatment 654890.0 1160.0 0.01 555502.0 -85500.0 -0.65 -0.4533 -0.6978 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G04 mock treatment 536345.0 -117000.0 -0.86 558243.0 -82800.0 -0.63 -1.0516 -0.9883 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G05 compound treatment 588606.0 -65100.0 -0.48 569865.0 -71100.0 -0.54 -0.7189 -0.998 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G06 compound treatment 625656.0 -28100.0 -0.21 535347.0 -106000.0 -0.8 -0.7127 -0.8603 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G07 compound treatment 639370.0 -14400.0 -0.11 621812.0 -19200.0 -0.15 -0.1773 -0.987 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G08 compound treatment 631764.0 -22000.0 -0.16 574848.0 -66200.0 -0.5 -0.4689 -0.8888 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G09 compound treatment 518811.0 -135000.0 -0.99 601953.0 -39000.0 -0.3 -0.9074 -0.8808 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G10 compound treatment 604968.0 -48800.0 -0.36 597346.0 -43700.0 -0.33 -0.4866 -0.9993 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G11 compound treatment 666267.0 12500.0 0.09 590273.0 -50700.0 -0.39 -0.2077 -0.5242 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G12 compound treatment 627304.0 -26400.0 -0.19 588118.0 -52900.0 -0.4 -0.4207 -0.9437 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G13 compound treatment 563954.0 -89800.0 -0.66 594994.0 -46000.0 -0.35 -0.7114 -0.9564 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G14 compound treatment 625282.0 -28400.0 -0.21 563281.0 -77700.0 -0.59 -0.5646 -0.9019 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G15 compound treatment 711549.0 57800.0 0.42 576824.0 -64200.0 -0.49 -0.0457 -0.0709 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G16 compound treatment 740308.0 86600.0 0.63 756001.0 115000.0 0.87 1.0655 0.9875 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G17 compound treatment 662715.0 8990.0 0.07 551998.0 -89000.0 -0.68 -0.4316 -0.6354 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G18 compound treatment 718925.0 65200.0 0.48 636986.0 -4010.0 -0.03 0.3156 0.6605 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G19 mock treatment 716937.0 63200.0 0.46 654572.0 13600.0 0.1 0.3998 0.8441 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G20 mock treatment 759296.0 106000.0 0.77 745921.0 105000.0 0.8 1.1095 0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G21 compound treatment 648090.0 -5640.0 -0.04 708927.0 67900.0 0.52 0.3357 0.6485 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G22 compound treatment 740768.0 87000.0 0.64 692681.0 51700.0 0.39 0.7277 0.973 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G23 compound treatment 654063.0 335.0 0.0 651814.0 10800.0 0.08 0.0598 0.7279 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 G24 compound treatment 620175.0 -33600.0 -0.25 609117.0 -31900.0 -0.24 -0.3448 -1.0 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H01 compound treatment 607109.0 -46600.0 -0.34 593699.0 -47300.0 -0.36 -0.4952 -0.9997 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H02 compound treatment 665752.0 12000.0 0.09 632542.0 -8460.0 -0.06 0.0167 0.1537 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H03 mock treatment 708909.0 55200.0 0.4 554562.0 -86400.0 -0.66 -0.179 -0.2322 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H04 mock treatment 633707.0 -20000.0 -0.15 538320.0 -103000.0 -0.78 -0.6551 -0.8254 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H05 compound treatment 569135.0 -84600.0 -0.62 648971.0 7970.0 0.06 -0.3946 -0.6349 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H06 compound treatment 697252.0 43500.0 0.32 611649.0 -29400.0 -0.22 0.0674 0.1734 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H07 compound treatment 637499.0 -16200.0 -0.12 691209.0 50200.0 0.38 0.1858 0.4651 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H08 compound treatment 600787.0 -52900.0 -0.39 532413.0 -109000.0 -0.82 -0.8571 -0.9405 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H09 compound treatment 571288.0 -82400.0 -0.6 733830.0 92800.0 0.71 0.0723 0.078 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H10 compound treatment 577847.0 -75900.0 -0.55 507333.0 -134000.0 -1.02 -1.1104 -0.9596 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H11 compound treatment 526639.0 -127000.0 -0.93 645862.0 4860.0 0.04 -0.6311 -0.6785 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H12 compound treatment 665446.0 11700.0 0.09 590782.0 -50200.0 -0.38 -0.2092 -0.5349 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H13 compound treatment 725614.0 71900.0 0.53 623039.0 -18000.0 -0.14 0.2752 0.5068 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H14 compound treatment 660357.0 6630.0 0.05 667016.0 26000.0 0.2 0.174 0.8552 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H15 compound treatment 669280.0 15600.0 0.11 604847.0 -36200.0 -0.27 -0.1138 -0.3828 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H16 compound treatment 671189.0 17500.0 0.13 658960.0 18000.0 0.14 0.1868 0.9995 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H17 compound treatment 739283.0 85600.0 0.63 673318.0 32300.0 0.25 0.616 0.9165 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H18 compound treatment 779976.0 126000.0 0.92 549069.0 -91900.0 -0.7 0.159 0.1374 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H19 mock treatment 695129.0 41400.0 0.3 573019.0 -68000.0 -0.52 -0.1511 -0.2524 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H20 mock treatment 701175.0 47400.0 0.35 737242.0 96200.0 0.73 0.7623 0.942 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H21 compound treatment 718505.0 64800.0 0.47 655630.0 14600.0 0.11 0.4136 0.8499 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H22 compound treatment 696221.0 42500.0 0.31 679839.0 38800.0 0.3 0.4284 0.9997 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H23 compound treatment 703007.0 49300.0 0.36 740788.0 99800.0 0.76 0.7909 0.9422 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 H24 compound treatment 590607.0 -63100.0 -0.46 616204.0 -24800.0 -0.19 -0.4596 -0.9219 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I01 compound treatment 555978.0 -97800.0 -0.71 570379.0 -70600.0 -0.54 -0.8848 -0.99 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I02 compound treatment 546197.0 -108000.0 -0.79 548320.0 -92700.0 -0.7 -1.0539 -0.9985 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I03 compound treatment 652580.0 -1150.0 -0.01 611151.0 -29800.0 -0.23 -0.1663 -0.7328 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I04 compound treatment 685896.0 32200.0 0.24 616414.0 -24600.0 -0.19 0.0343 0.1141 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I05 mock treatment 640710.0 -13000.0 -0.1 564514.0 -76500.0 -0.58 -0.4782 -0.8121 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I06 mock treatment 537569.0 -116000.0 -0.85 676651.0 35700.0 0.27 -0.4092 -0.4589 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I07 compound treatment 706256.0 52500.0 0.38 595076.0 -45900.0 -0.35 0.0249 0.0481 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I08 compound treatment 729022.0 75300.0 0.55 563884.0 -77100.0 -0.59 -0.0249 -0.031 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I09 compound treatment 713903.0 60200.0 0.44 647144.0 6140.0 0.05 0.3442 0.7777 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I10 compound treatment 531317.0 -122000.0 -0.9 577830.0 -63200.0 -0.48 -0.9723 -0.9573 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I11 compound treatment 668010.0 14300.0 0.1 709494.0 68500.0 0.52 0.4418 0.8324 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I12 compound treatment 615002.0 -38700.0 -0.28 555406.0 -85600.0 -0.65 -0.66 -0.9306 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I13 compound treatment 667018.0 13300.0 0.1 607342.0 -33700.0 -0.26 -0.1121 -0.4097 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I14 compound treatment 596768.0 -57000.0 -0.42 671365.0 30400.0 0.23 -0.1314 -0.276 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I15 compound treatment 802163.0 148000.0 1.09 647836.0 6840.0 0.05 0.8043 0.7401 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I16 compound treatment 812903.0 159000.0 1.16 689082.0 48100.0 0.37 1.0814 0.8864 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I17 compound treatment 726879.0 73200.0 0.53 641129.0 129.0 0.0 0.379 0.7084 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I18 compound treatment 707982.0 54300.0 0.4 742399.0 101000.0 0.77 0.8252 0.9524 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I19 compound treatment 719458.0 65700.0 0.48 723167.0 82200.0 0.62 0.7813 0.9917 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I20 compound treatment 712875.0 59100.0 0.43 684372.0 43400.0 0.33 0.5388 0.991 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I21 mock treatment 588733.0 -65000.0 -0.48 682922.0 41900.0 0.32 -0.1109 -0.1938 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I22 mock treatment 651670.0 -2060.0 -0.02 701305.0 60300.0 0.46 0.3133 0.6835 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I23 compound treatment 689039.0 35300.0 0.26 730174.0 89200.0 0.68 0.6616 0.9126 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 I24 compound treatment 626032.0 -27700.0 -0.2 663496.0 22500.0 0.17 -0.0224 -0.0844 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J01 compound treatment 635278.0 -18500.0 -0.13 618482.0 -22500.0 -0.17 -0.2164 -0.9931 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J02 compound treatment 602714.0 -51000.0 -0.37 608502.0 -32500.0 -0.25 -0.4384 -0.9799 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J03 compound treatment 522608.0 -131000.0 -0.96 577706.0 -63300.0 -0.48 -1.018 -0.949 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J04 compound treatment 620215.0 -33500.0 -0.25 553824.0 -87200.0 -0.66 -0.6416 -0.9086 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J05 mock treatment 597538.0 -56200.0 -0.41 566520.0 -74500.0 -0.57 -0.6907 -0.9877 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J06 mock treatment 523180.0 -131000.0 -0.95 620195.0 -20800.0 -0.16 -0.7868 -0.8131 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J07 compound treatment 683621.0 29900.0 0.22 575904.0 -65100.0 -0.49 -0.1951 -0.3608 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J08 compound treatment 540601.0 -113000.0 -0.83 562804.0 -78200.0 -0.59 -1.005 -0.9868 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J09 compound treatment 517122.0 -137000.0 -1.0 599972.0 -41000.0 -0.31 -0.9268 -0.8856 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J10 compound treatment 643319.0 -10400.0 -0.08 577928.0 -63100.0 -0.48 -0.3926 -0.8093 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J11 compound treatment 669178.0 15400.0 0.11 603152.0 -37800.0 -0.29 -0.1234 -0.3995 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J12 compound treatment 765906.0 112000.0 0.82 555699.0 -85300.0 -0.65 0.1219 0.1166 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J13 compound treatment 787011.0 133000.0 0.97 608183.0 -32800.0 -0.25 0.5129 0.5098 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J14 compound treatment 669564.0 15800.0 0.12 748112.0 107000.0 0.81 0.6573 0.7997 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J15 compound treatment 712996.0 59300.0 0.43 622901.0 -18100.0 -0.14 0.2093 0.4602 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J16 compound treatment 719903.0 66200.0 0.48 646063.0 5060.0 0.04 0.3694 0.7609 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J17 compound treatment 785054.0 131000.0 0.96 604220.0 -36800.0 -0.28 0.4815 0.4814 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J18 compound treatment 718408.0 64700.0 0.47 565993.0 -75000.0 -0.57 -0.0685 -0.0924 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J19 compound treatment 572901.0 -80800.0 -0.59 705968.0 65000.0 0.49 -0.069 -0.0896 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J20 compound treatment 728501.0 74800.0 0.55 637061.0 -3940.0 -0.03 0.3655 0.6674 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J21 mock treatment 745073.0 91300.0 0.67 787651.0 147000.0 1.11 1.2601 0.9701 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J22 mock treatment 755452.0 102000.0 0.74 701035.0 60000.0 0.46 0.8485 0.9724 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J23 compound treatment 620880.0 -32800.0 -0.24 726571.0 85600.0 0.65 0.2898 0.4182 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 J24 compound treatment 711226.0 57500.0 0.42 630341.0 -10700.0 -0.08 0.2401 0.5606 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K01 compound treatment 585048.0 -68700.0 -0.5 661283.0 20300.0 0.15 -0.2462 -0.4686 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K02 compound treatment 602380.0 -51300.0 -0.38 639894.0 -1110.0 -0.01 -0.2715 -0.7228 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K03 compound treatment 472941.0 -181000.0 -1.32 687705.0 46700.0 0.35 -0.684 -0.4997 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K04 compound treatment 636203.0 -17500.0 -0.13 672346.0 31300.0 0.24 0.0778 0.2875 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K05 compound treatment 757570.0 104000.0 0.76 658359.0 17400.0 0.13 0.6302 0.8177 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K06 compound treatment 773257.0 120000.0 0.87 622583.0 -18400.0 -0.14 0.5192 0.5865 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K07 mock treatment 754347.0 101000.0 0.74 725930.0 84900.0 0.65 0.9765 0.9979 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K08 mock treatment 714346.0 60600.0 0.44 621430.0 -19600.0 -0.15 0.2083 0.4456 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K09 compound treatment 690337.0 36600.0 0.27 647844.0 6840.0 0.05 0.2261 0.8289 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K10 compound treatment 678365.0 24600.0 0.18 514134.0 -127000.0 -0.96 -0.5541 -0.5651 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K11 compound treatment 810934.0 157000.0 1.15 529740.0 -111000.0 -0.85 0.2153 0.1509 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K12 compound treatment 683912.0 30200.0 0.22 713491.0 72500.0 0.55 0.5455 0.9194 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K13 compound treatment 692029.0 38300.0 0.28 573452.0 -67500.0 -0.51 -0.1648 -0.2819 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K14 compound treatment 777601.0 124000.0 0.91 608865.0 -32100.0 -0.24 0.4679 0.4988 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K15 mock treatment 704491.0 50800.0 0.37 675691.0 34700.0 0.26 0.4489 0.9859 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K16 mock treatment 675326.0 21600.0 0.16 693678.0 52700.0 0.4 0.3947 0.9173 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K17 compound treatment 735078.0 81300.0 0.59 707034.0 66000.0 0.5 0.7754 0.9964 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K18 compound treatment 732020.0 78300.0 0.57 650041.0 9040.0 0.07 0.4534 0.7863 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K19 compound treatment 693432.0 39700.0 0.29 766303.0 125000.0 0.95 0.8784 0.8826 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K20 compound treatment 739172.0 85400.0 0.62 732910.0 91900.0 0.7 0.9356 0.9985 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K21 compound treatment 770605.0 117000.0 0.85 706340.0 65300.0 0.5 0.9554 0.9666 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K22 compound treatment 713432.0 59700.0 0.44 710025.0 69000.0 0.52 0.6795 0.9959 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K23 mock treatment 620760.0 -33000.0 -0.24 720010.0 79000.0 0.6 0.2539 0.3926 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 K24 mock treatment 664680.0 11000.0 0.08 662657.0 21700.0 0.16 0.173 0.9453 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L01 compound treatment 612893.0 -40800.0 -0.3 711372.0 70400.0 0.53 0.1669 0.2725 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L02 compound treatment 593963.0 -59800.0 -0.44 535488.0 -106000.0 -0.8 -0.8758 -0.9593 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L03 compound treatment 597691.0 -56000.0 -0.41 538441.0 -103000.0 -0.78 -0.8407 -0.955 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L04 compound treatment 648804.0 -4920.0 -0.04 471877.0 -169000.0 -1.28 -0.9339 -0.7266 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L05 compound treatment 733142.0 79400.0 0.58 653557.0 12600.0 0.1 0.4781 0.8124 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L06 compound treatment 685482.0 31800.0 0.23 459822.0 -181000.0 -1.38 -0.809 -0.5796 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L07 mock treatment 658684.0 4960.0 0.04 562424.0 -78600.0 -0.6 -0.3965 -0.663 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L08 mock treatment 680081.0 26400.0 0.19 596924.0 -44100.0 -0.33 -0.1005 -0.2601 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L09 compound treatment 750254.0 96500.0 0.71 556898.0 -84100.0 -0.64 0.0474 0.0498 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L10 compound treatment 607962.0 -45800.0 -0.33 644635.0 3630.0 0.03 -0.2171 -0.6466 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L11 compound treatment 711328.0 57600.0 0.42 712229.0 71200.0 0.54 0.6805 0.9923 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L12 compound treatment 596757.0 -57000.0 -0.42 488834.0 -152000.0 -1.16 -1.112 -0.905 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L13 compound treatment 742562.0 88800.0 0.65 700401.0 59400.0 0.45 0.7785 0.9841 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L14 compound treatment 709866.0 56100.0 0.41 549332.0 -91700.0 -0.7 -0.2021 -0.25 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L15 mock treatment 622550.0 -31200.0 -0.23 736333.0 95300.0 0.72 0.3509 0.4621 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L16 mock treatment 717162.0 63400.0 0.46 780426.0 139000.0 1.06 1.077 0.9314 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L17 compound treatment 721913.0 68200.0 0.5 732203.0 91200.0 0.69 0.8425 0.987 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L18 compound treatment 616286.0 -37400.0 -0.27 574621.0 -66400.0 -0.5 -0.5502 -0.9588 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L19 compound treatment 693847.0 40100.0 0.29 609386.0 -31600.0 -0.24 0.0376 0.0993 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L20 compound treatment 656359.0 2630.0 0.02 624518.0 -16500.0 -0.13 -0.0749 -0.5915 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L21 compound treatment 738588.0 84900.0 0.62 723409.0 82400.0 0.63 0.8815 1.0 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L22 compound treatment 742578.0 88800.0 0.65 697022.0 56000.0 0.43 0.7604 0.979 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L23 mock treatment 615612.0 -38100.0 -0.28 734305.0 93300.0 0.71 0.3041 0.3993 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 L24 mock treatment 691678.0 37900.0 0.28 718160.0 77200.0 0.59 0.6107 0.9417 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M01 compound treatment 576760.0 -77000.0 -0.56 696933.0 55900.0 0.42 -0.0976 -0.1383 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M02 compound treatment 721948.0 68200.0 0.5 671593.0 30600.0 0.23 0.5171 0.9396 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M03 compound treatment 678685.0 25000.0 0.18 702058.0 61100.0 0.46 0.457 0.9169 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M04 compound treatment 714385.0 60700.0 0.44 648867.0 7870.0 0.06 0.3559 0.7952 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M05 compound treatment 707655.0 53900.0 0.39 715052.0 74100.0 0.56 0.6766 0.9849 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M06 compound treatment 675429.0 21700.0 0.16 657809.0 16800.0 0.13 0.2025 0.9942 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M07 compound treatment 679047.0 25300.0 0.19 668803.0 27800.0 0.21 0.2803 0.9978 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M08 compound treatment 770981.0 117000.0 0.86 565455.0 -75500.0 -0.57 0.2005 0.1943 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M09 mock treatment 763958.0 110000.0 0.81 616641.0 -24400.0 -0.19 0.4392 0.531 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M10 mock treatment 754495.0 101000.0 0.74 601532.0 -39500.0 -0.3 0.3091 0.3885 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M11 compound treatment 663733.0 10000.0 0.07 560377.0 -80600.0 -0.61 -0.3814 -0.6182 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M12 compound treatment 584499.0 -69200.0 -0.51 761936.0 121000.0 0.92 0.2916 0.278 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M13 mock treatment 790922.0 137000.0 1.0 546976.0 -94000.0 -0.71 0.2044 0.1659 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M14 mock treatment 663365.0 9640.0 0.07 617574.0 -23400.0 -0.18 -0.076 -0.3971 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M15 compound treatment 700765.0 47000.0 0.34 677770.0 36800.0 0.28 0.4408 0.9947 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M16 compound treatment 788187.0 134000.0 0.98 735413.0 94400.0 0.72 1.2025 0.988 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M17 compound treatment 722281.0 68600.0 0.5 752199.0 111000.0 0.84 0.9518 0.969 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M18 compound treatment 815735.0 162000.0 1.18 680149.0 39100.0 0.3 1.0481 0.858 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M19 compound treatment 717135.0 63400.0 0.46 732766.0 91800.0 0.7 0.8208 0.9804 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M20 compound treatment 863201.0 209000.0 1.53 669366.0 28400.0 0.22 1.2356 0.7987 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M21 compound treatment 641242.0 -12500.0 -0.09 738847.0 97800.0 0.74 0.461 0.6156 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M22 compound treatment 788254.0 135000.0 0.98 787586.0 147000.0 1.11 1.4831 0.9981 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M23 compound treatment 762704.0 109000.0 0.8 761867.0 121000.0 0.92 1.2128 0.9975 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 M24 compound treatment 638062.0 -15700.0 -0.11 757873.0 117000.0 0.89 0.5468 0.6108 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N01 compound treatment 663280.0 9550.0 0.07 678421.0 37400.0 0.28 0.2504 0.8554 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N02 compound treatment 767542.0 114000.0 0.83 783081.0 142000.0 1.08 1.3518 0.9918 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N03 compound treatment 737409.0 83700.0 0.61 713539.0 72500.0 0.55 0.8224 0.9986 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N04 compound treatment 728519.0 74800.0 0.55 641755.0 755.0 0.01 0.3908 0.7145 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N05 compound treatment 785902.0 132000.0 0.97 683205.0 42200.0 0.32 0.9102 0.8938 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N06 compound treatment 637133.0 -16600.0 -0.12 726498.0 85500.0 0.65 0.3735 0.5652 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N07 compound treatment 786034.0 132000.0 0.97 720756.0 79800.0 0.61 1.1126 0.9746 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N08 compound treatment 750316.0 96600.0 0.71 597682.0 -43300.0 -0.33 0.2668 0.3423 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N09 mock treatment 549116.0 -105000.0 -0.77 755715.0 115000.0 0.87 0.0753 0.0649 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N10 mock treatment 748756.0 95000.0 0.69 695137.0 54100.0 0.41 0.7822 0.9687 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N11 compound treatment 765022.0 111000.0 0.81 734032.0 93000.0 0.71 1.0753 0.9975 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N12 compound treatment 747609.0 93900.0 0.69 739993.0 99000.0 0.75 1.0172 0.999 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N13 mock treatment 588451.0 -65300.0 -0.48 676027.0 35000.0 0.27 -0.1494 -0.2734 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N14 mock treatment 659808.0 6080.0 0.04 704178.0 63200.0 0.48 0.3708 0.7693 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N15 compound treatment 788092.0 134000.0 0.98 716882.0 75900.0 0.58 1.1024 0.9677 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N16 compound treatment 755282.0 102000.0 0.74 839819.0 199000.0 1.51 1.5932 0.9466 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N17 compound treatment 649103.0 -4630.0 -0.03 758293.0 117000.0 0.89 0.6061 0.6798 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N18 compound treatment 783585.0 130000.0 0.95 679282.0 38300.0 0.29 0.8771 0.8832 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N19 compound treatment 710944.0 57200.0 0.42 711341.0 70300.0 0.53 0.6737 0.9927 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N20 compound treatment 776045.0 122000.0 0.89 599667.0 -41300.0 -0.31 0.4105 0.433 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N21 compound treatment 720823.0 67100.0 0.49 703921.0 62900.0 0.48 0.685 0.9999 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N22 compound treatment 748340.0 94600.0 0.69 782145.0 141000.0 1.07 1.2474 0.9775 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N23 compound treatment 699330.0 45600.0 0.33 768717.0 128000.0 0.97 0.9219 0.8986 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 N24 compound treatment 783156.0 129000.0 0.95 656131.0 15100.0 0.11 0.7506 0.7872 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O01 compound treatment 584754.0 -69000.0 -0.5 751900.0 111000.0 0.84 0.239 0.2434 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O02 compound treatment 651725.0 -2000.0 -0.01 615936.0 -25100.0 -0.19 -0.145 -0.7593 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O03 compound treatment 742070.0 88300.0 0.65 721387.0 80400.0 0.61 0.8886 0.9996 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O04 compound treatment 694328.0 40600.0 0.3 588363.0 -52600.0 -0.4 -0.0728 -0.1462 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O05 compound treatment 838546.0 185000.0 1.35 702280.0 61300.0 0.47 1.2849 0.8988 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O06 compound treatment 805197.0 151000.0 1.11 642001.0 1000.0 0.01 0.7886 0.7119 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O07 compound treatment 710162.0 56400.0 0.41 687528.0 46500.0 0.35 0.5418 0.997 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O08 compound treatment 601385.0 -52300.0 -0.38 586408.0 -54600.0 -0.41 -0.5639 -0.9992 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O09 compound treatment 737119.0 83400.0 0.61 615308.0 -25700.0 -0.2 0.2932 0.4579 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O10 compound treatment 744682.0 91000.0 0.67 697686.0 56700.0 0.43 0.7748 0.9779 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O11 mock treatment 723033.0 69300.0 0.51 672596.0 31600.0 0.24 0.5281 0.9417 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O12 mock treatment 777756.0 124000.0 0.91 618853.0 -22100.0 -0.17 0.5224 0.5663 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O13 compound treatment 733427.0 79700.0 0.58 723929.0 82900.0 0.63 0.8576 0.9992 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O14 compound treatment 764151.0 110000.0 0.81 675352.0 34400.0 0.26 0.7555 0.8903 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O15 compound treatment 918226.0 264000.0 1.93 789045.0 148000.0 1.12 2.163 0.9667 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O16 compound treatment 749662.0 95900.0 0.7 761722.0 121000.0 0.92 1.1446 0.9913 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O17 compound treatment 789308.0 136000.0 0.99 700940.0 59900.0 0.46 1.0231 0.9377 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O18 compound treatment 840872.0 187000.0 1.37 635904.0 -5100.0 -0.04 0.9404 0.6868 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O19 compound treatment 874242.0 221000.0 1.61 770700.0 130000.0 0.99 1.837 0.9721 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O20 compound treatment 858265.0 205000.0 1.5 710474.0 69500.0 0.53 1.4309 0.9021 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O21 compound treatment 795337.0 142000.0 1.04 711484.0 70500.0 0.54 1.1109 0.9529 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O22 compound treatment 806808.0 153000.0 1.12 718187.0 77200.0 0.59 1.2062 0.9545 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O23 compound treatment 765659.0 112000.0 0.82 734600.0 93600.0 0.71 1.0816 0.9975 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 O24 compound treatment 715062.0 61300.0 0.45 674821.0 33800.0 0.26 0.4988 0.965 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P01 compound treatment 905230.0 252000.0 1.84 685985.0 45000.0 0.34 1.5422 0.8244 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P02 compound treatment 809541.0 156000.0 1.14 720385.0 79400.0 0.6 1.2322 0.9557 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P03 compound treatment 738682.0 85000.0 0.62 824064.0 183000.0 1.39 1.4227 0.934 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P04 compound treatment 740557.0 86800.0 0.63 715446.0 74400.0 0.57 0.8489 0.9983 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P05 compound treatment 746176.0 92400.0 0.68 613665.0 -27300.0 -0.21 0.3312 0.4683 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P06 compound treatment 792201.0 138000.0 1.01 688212.0 47200.0 0.36 0.9697 0.9026 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P07 compound treatment 738220.0 84500.0 0.62 708054.0 67100.0 0.51 0.7971 0.9954 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P08 compound treatment 721430.0 67700.0 0.5 729121.0 88100.0 0.67 0.8235 0.989 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P09 compound treatment 734810.0 81100.0 0.59 783211.0 142000.0 1.08 1.1832 0.9601 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P10 compound treatment 699890.0 46200.0 0.34 766727.0 126000.0 0.96 0.9141 0.9023 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P11 mock treatment 855465.0 202000.0 1.48 754620.0 114000.0 0.86 1.6535 0.9674 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P12 mock treatment 843624.0 190000.0 1.39 736282.0 95300.0 0.72 1.4938 0.9539 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P13 compound treatment 896955.0 243000.0 1.78 780082.0 139000.0 1.06 2.0049 0.9691 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P14 compound treatment 786487.0 133000.0 0.97 576671.0 -64300.0 -0.49 0.341 0.3137 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P15 compound treatment 915475.0 262000.0 1.91 772660.0 132000.0 1.0 2.0608 0.9542 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P16 compound treatment 739649.0 85900.0 0.63 739956.0 99000.0 0.75 0.9759 0.996 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P17 compound treatment 792286.0 139000.0 1.01 737597.0 96600.0 0.73 1.2354 0.9874 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P18 compound treatment 830880.0 177000.0 1.3 794656.0 154000.0 1.17 1.7415 0.9986 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P19 compound treatment 862178.0 208000.0 1.52 772215.0 131000.0 1.0 1.7828 0.9788 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P20 compound treatment 787406.0 134000.0 0.98 742514.0 102000.0 0.77 1.2366 0.9931 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P21 compound treatment 798302.0 145000.0 1.06 800460.0 159000.0 1.21 1.6042 0.9977 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P22 compound treatment 736288.0 82600.0 0.6 766806.0 126000.0 0.96 1.1027 0.9755 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P23 compound treatment 739148.0 85400.0 0.62 758201.0 117000.0 0.89 1.0713 0.985 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2101 P24 compound treatment 727024.0 73300.0 0.54 703864.0 62900.0 0.48 0.7167 0.9983 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A01 compound treatment 549227.0 -4840.0 -0.04 627011.0 33000.0 0.25 0.1522 0.6012 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A02 compound treatment 461053.0 -93000.0 -0.68 493903.0 -100000.0 -0.76 -1.0187 -0.9985 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A03 compound treatment 249954.0 -304000.0 -2.22 336728.0 -257000.0 -1.95 -2.9547 -0.9979 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A04 compound treatment 196812.0 -357000.0 -2.61 173473.0 -421000.0 -3.19 -4.1064 -0.995 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A05 compound treatment 452786.0 -101000.0 -0.74 465949.0 -128000.0 -0.97 -1.2116 -0.991 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A06 compound treatment 320701.0 -233000.0 -1.71 427455.0 -167000.0 -1.27 -2.1015 -0.9891 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A07 compound treatment 126759.0 -427000.0 -3.12 119477.0 -475000.0 -3.6 -4.7587 -0.9975 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A08 compound treatment 275524.0 -279000.0 -2.04 346310.0 -248000.0 -1.88 -2.771 -0.9992 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A09 compound treatment 411511.0 -143000.0 -1.04 466256.0 -128000.0 -0.97 -1.4234 -0.9994 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A10 compound treatment 422005.0 -132000.0 -0.97 485794.0 -108000.0 -0.82 -1.2642 -0.9968 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A11 compound treatment 369724.0 -184000.0 -1.35 357743.0 -236000.0 -1.79 -2.2224 -0.9901 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A12 compound treatment 533588.0 -20500.0 -0.15 454726.0 -139000.0 -1.06 -0.8541 -0.7992 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A13 mock treatment 614687.0 60600.0 0.44 579912.0 -14100.0 -0.11 0.2377 0.5213 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A14 mock treatment 513869.0 -40200.0 -0.29 639983.0 46000.0 0.35 0.0391 0.0856 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A15 compound treatment 129753.0 -424000.0 -3.1 137881.0 -456000.0 -3.47 -4.6444 -0.9985 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A16 compound treatment 154650.0 -399000.0 -2.92 148620.0 -445000.0 -3.38 -4.458 -0.9973 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A17 compound treatment 273660.0 -280000.0 -2.05 192962.0 -401000.0 -3.05 -3.6043 -0.9814 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A18 compound treatment 131486.0 -423000.0 -3.09 147498.0 -447000.0 -3.39 -4.5838 -0.9989 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A19 compound treatment 126284.0 -428000.0 -3.13 136413.0 -458000.0 -3.48 -4.6702 -0.9986 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A20 compound treatment 346053.0 -208000.0 -1.52 317594.0 -276000.0 -2.1 -2.5605 -0.9875 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A21 compound treatment 487209.0 -66900.0 -0.49 585035.0 -8970.0 -0.07 -0.3939 -0.7979 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A22 compound treatment 255410.0 -299000.0 -2.18 428853.0 -165000.0 -1.25 -2.4316 -0.9654 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A23 compound treatment 514779.0 -39300.0 -0.29 480727.0 -113000.0 -0.86 -0.8117 -0.8947 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 A24 compound treatment 466694.0 -87400.0 -0.64 453872.0 -140000.0 -1.06 -1.2046 -0.9702 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B01 compound treatment 501974.0 -52100.0 -0.38 495586.0 -98400.0 -0.75 -0.7981 -0.9511 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B02 compound treatment 503181.0 -50900.0 -0.37 465966.0 -128000.0 -0.97 -0.951 -0.9131 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B03 compound treatment 468504.0 -85600.0 -0.63 577448.0 -16600.0 -0.13 -0.5314 -0.8326 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B04 compound treatment 458204.0 -95900.0 -0.7 489949.0 -104000.0 -0.79 -1.0547 -0.9982 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B05 compound treatment 317415.0 -237000.0 -1.73 274285.0 -320000.0 -2.43 -2.9412 -0.9862 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B06 compound treatment 418360.0 -136000.0 -0.99 523264.0 -70700.0 -0.54 -1.0818 -0.9585 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B07 compound treatment 402870.0 -151000.0 -1.11 456219.0 -138000.0 -1.05 -1.522 -0.9996 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B08 compound treatment 424777.0 -129000.0 -0.95 422675.0 -171000.0 -1.3 -1.5889 -0.9877 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B09 compound treatment 296363.0 -258000.0 -1.88 439085.0 -155000.0 -1.18 -2.1648 -0.9743 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B10 compound treatment 521630.0 -32400.0 -0.24 542791.0 -51200.0 -0.39 -0.4429 -0.9719 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B11 compound treatment 568633.0 14600.0 0.11 551332.0 -42700.0 -0.32 -0.1539 -0.4511 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B12 compound treatment 410682.0 -143000.0 -1.05 494786.0 -99200.0 -0.75 -1.2745 -0.9869 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B13 mock treatment 569122.0 15100.0 0.11 603201.0 9200.0 0.07 0.1272 0.9759 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B14 mock treatment 583202.0 29100.0 0.21 579099.0 -14900.0 -0.11 0.0706 0.2925 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B15 compound treatment 444991.0 -109000.0 -0.8 531581.0 -62400.0 -0.47 -0.8994 -0.9691 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B16 compound treatment 256392.0 -298000.0 -2.18 397905.0 -196000.0 -1.49 -2.5927 -0.9829 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B17 compound treatment 630210.0 76100.0 0.56 585747.0 -8260.0 -0.06 0.3494 0.6235 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B18 compound treatment 404583.0 -149000.0 -1.09 441312.0 -153000.0 -1.16 -1.5933 -0.9996 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B19 compound treatment 564977.0 10900.0 0.08 563424.0 -30600.0 -0.23 -0.1079 -0.4392 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B20 compound treatment 452846.0 -101000.0 -0.74 387671.0 -206000.0 -1.57 -1.6318 -0.9414 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B21 compound treatment 138911.0 -415000.0 -3.04 140502.0 -454000.0 -3.45 -4.583 -0.998 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B22 compound treatment 487088.0 -67000.0 -0.49 529401.0 -64600.0 -0.49 -0.6934 -1.0 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B23 compound treatment 545328.0 -8740.0 -0.06 594371.0 366.0 0.0 -0.0432 -0.6757 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 B24 compound treatment 264799.0 -289000.0 -2.12 322684.0 -271000.0 -2.06 -2.9533 -0.9999 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C01 compound treatment 525689.0 -28400.0 -0.21 573061.0 -20900.0 -0.16 -0.2593 -0.9914 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C02 compound treatment 448355.0 -106000.0 -0.77 494311.0 -99700.0 -0.76 -1.0822 -0.9999 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C03 compound treatment 480722.0 -73300.0 -0.54 524123.0 -69900.0 -0.53 -0.7547 -1.0 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C04 compound treatment 529273.0 -24800.0 -0.18 657889.0 63900.0 0.49 0.2149 0.4149 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C05 compound treatment 465721.0 -88400.0 -0.65 546326.0 -47700.0 -0.36 -0.713 -0.9626 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C06 compound treatment 126199.0 -428000.0 -3.13 124546.0 -469000.0 -3.57 -4.7344 -0.9979 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C07 compound treatment 448244.0 -106000.0 -0.77 418359.0 -176000.0 -1.33 -1.4908 -0.9664 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C08 compound treatment 261872.0 -292000.0 -2.14 267973.0 -326000.0 -2.48 -3.2624 -0.9973 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C09 compound treatment 124905.0 -429000.0 -3.14 119727.0 -474000.0 -3.6 -4.767 -0.9976 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C10 compound treatment 195582.0 -358000.0 -2.62 219075.0 -375000.0 -2.85 -3.8678 -0.9991 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C11 mock treatment 567771.0 13700.0 0.1 611358.0 17400.0 0.13 0.1641 0.9908 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C12 mock treatment 448971.0 -105000.0 -0.77 614978.0 21000.0 0.16 -0.4308 -0.5489 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C13 compound treatment 398425.0 -156000.0 -1.14 556208.0 -37800.0 -0.29 -1.0079 -0.8586 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C14 compound treatment 136796.0 -417000.0 -3.05 131671.0 -462000.0 -3.51 -4.6413 -0.9975 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C15 mock treatment 463223.0 -90800.0 -0.66 654213.0 60200.0 0.46 -0.1464 -0.1815 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C16 mock treatment 573773.0 19700.0 0.14 637812.0 43800.0 0.33 0.3372 0.9298 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C17 compound treatment 204167.0 -350000.0 -2.56 189514.0 -404000.0 -3.07 -3.9822 -0.9959 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C18 compound treatment 385266.0 -169000.0 -1.23 399407.0 -195000.0 -1.48 -1.9182 -0.996 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C19 compound treatment 173860.0 -380000.0 -2.78 183384.0 -411000.0 -3.12 -4.1719 -0.9984 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C20 compound treatment 185857.0 -368000.0 -2.69 162048.0 -432000.0 -3.28 -4.2244 -0.9952 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C21 compound treatment 570347.0 16300.0 0.12 608313.0 14300.0 0.11 0.161 0.999 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C22 compound treatment 274534.0 -280000.0 -2.04 302106.0 -292000.0 -2.22 -3.0135 -0.9992 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C23 compound treatment 291083.0 -263000.0 -1.92 305291.0 -289000.0 -2.19 -2.9108 -0.9979 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 C24 compound treatment 140673.0 -413000.0 -3.02 157131.0 -437000.0 -3.32 -4.4845 -0.9989 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D01 compound treatment 386920.0 -167000.0 -1.22 396267.0 -198000.0 -1.5 -1.9266 -0.9948 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D02 compound treatment 509586.0 -44500.0 -0.33 555851.0 -38200.0 -0.29 -0.435 -0.9983 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D03 compound treatment 537603.0 -16500.0 -0.12 474595.0 -119000.0 -0.91 -0.7266 -0.794 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D04 compound treatment 490673.0 -63400.0 -0.46 641373.0 47400.0 0.36 -0.0734 -0.1251 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D05 compound treatment 358280.0 -196000.0 -1.43 373187.0 -221000.0 -1.68 -2.1986 -0.9969 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D06 compound treatment 432216.0 -122000.0 -0.89 527358.0 -66600.0 -0.51 -0.9881 -0.9641 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D07 compound treatment 532417.0 -21700.0 -0.16 514142.0 -79900.0 -0.61 -0.541 -0.8628 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D08 compound treatment 402238.0 -152000.0 -1.11 551065.0 -42900.0 -0.33 -1.0158 -0.8777 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D09 compound treatment 347571.0 -207000.0 -1.51 486854.0 -107000.0 -0.81 -1.6434 -0.9579 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D10 compound treatment 480389.0 -73700.0 -0.54 530305.0 -63700.0 -0.48 -0.7232 -0.9986 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D11 mock treatment 498600.0 -55500.0 -0.41 478358.0 -116000.0 -0.88 -0.9081 -0.9384 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D12 mock treatment 493964.0 -60100.0 -0.44 569542.0 -24500.0 -0.19 -0.4422 -0.9266 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D13 compound treatment 615432.0 61400.0 0.45 651938.0 57900.0 0.44 0.6285 1.0 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D14 compound treatment 368061.0 -186000.0 -1.36 491373.0 -103000.0 -0.78 -1.5132 -0.9651 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D15 mock treatment 557586.0 3510.0 0.03 565258.0 -28700.0 -0.22 -0.1362 -0.6196 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D16 mock treatment 571743.0 17700.0 0.13 519494.0 -74500.0 -0.57 -0.3089 -0.532 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D17 compound treatment 521044.0 -33000.0 -0.24 479748.0 -114000.0 -0.87 -0.7845 -0.8708 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D18 compound treatment 516772.0 -37300.0 -0.27 590575.0 -3430.0 -0.03 -0.2113 -0.7711 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D19 compound treatment 314567.0 -240000.0 -1.75 242075.0 -352000.0 -2.67 -3.129 -0.979 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D20 compound treatment 410274.0 -144000.0 -1.05 428995.0 -165000.0 -1.25 -1.63 -0.9962 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D21 compound treatment 574940.0 20900.0 0.15 595283.0 1280.0 0.01 0.1148 0.7506 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D22 compound treatment 600718.0 46600.0 0.34 677944.0 83900.0 0.64 0.6921 0.957 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D23 compound treatment 547515.0 -6560.0 -0.05 482650.0 -111000.0 -0.85 -0.6321 -0.746 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 D24 compound treatment 534572.0 -19500.0 -0.14 580759.0 -13200.0 -0.1 -0.172 -0.9854 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E01 mock treatment 481576.0 -72500.0 -0.53 577777.0 -16200.0 -0.12 -0.4621 -0.8489 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E02 mock treatment 426315.0 -128000.0 -0.93 576176.0 -17800.0 -0.14 -0.7564 -0.8012 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E03 compound treatment 438351.0 -116000.0 -0.85 462242.0 -132000.0 -1.0 -1.3062 -0.9965 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E04 compound treatment 361316.0 -193000.0 -1.41 379530.0 -214000.0 -1.63 -2.1489 -0.9974 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E05 compound treatment 285031.0 -269000.0 -1.97 322726.0 -271000.0 -2.06 -2.8485 -0.9997 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E06 compound treatment 465643.0 -88400.0 -0.65 554256.0 -39700.0 -0.3 -0.6708 -0.9399 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E07 compound treatment 133050.0 -421000.0 -3.08 136289.0 -458000.0 -3.48 -4.6359 -0.9982 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E08 compound treatment 135049.0 -419000.0 -3.06 136259.0 -458000.0 -3.48 -4.6257 -0.998 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E09 mock treatment 581117.0 27000.0 0.2 538642.0 -55400.0 -0.42 -0.1575 -0.339 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E10 mock treatment 454240.0 -99800.0 -0.73 621189.0 27200.0 0.21 -0.3702 -0.4879 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E11 compound treatment 412792.0 -141000.0 -1.03 435701.0 -158000.0 -1.2 -1.5809 -0.9971 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E12 compound treatment 268552.0 -286000.0 -2.09 224115.0 -370000.0 -2.81 -3.4634 -0.9893 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E13 compound treatment 367822.0 -186000.0 -1.36 318675.0 -275000.0 -2.09 -2.4421 -0.9784 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E14 compound treatment 300436.0 -254000.0 -1.85 323947.0 -270000.0 -2.05 -2.7623 -0.9987 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E15 compound treatment 130426.0 -424000.0 -3.1 134128.0 -460000.0 -3.49 -4.6611 -0.9982 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E16 compound treatment 555705.0 1630.0 0.01 648357.0 54400.0 0.41 0.3004 0.7273 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E17 mock treatment 504120.0 -50000.0 -0.37 610413.0 16400.0 0.12 -0.1702 -0.4409 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E18 mock treatment 589358.0 35300.0 0.26 539541.0 -54500.0 -0.41 -0.1101 -0.2258 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E19 compound treatment 384948.0 -169000.0 -1.24 440696.0 -153000.0 -1.16 -1.6981 -0.9995 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E20 compound treatment 668374.0 114000.0 0.84 697441.0 103000.0 0.79 1.1467 0.9995 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E21 compound treatment 454079.0 -100000.0 -0.73 580195.0 -13800.0 -0.1 -0.5913 -0.8004 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E22 compound treatment 122873.0 -431000.0 -3.15 125535.0 -468000.0 -3.56 -4.7463 -0.9982 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E23 compound treatment 504698.0 -49400.0 -0.36 507401.0 -86600.0 -0.66 -0.7205 -0.9601 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 E24 compound treatment 466956.0 -87100.0 -0.64 530359.0 -63600.0 -0.48 -0.7924 -0.9907 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F01 mock treatment 520260.0 -33800.0 -0.25 567084.0 -26900.0 -0.2 -0.3195 -0.9956 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F02 mock treatment 494635.0 -59400.0 -0.43 568426.0 -25600.0 -0.19 -0.4448 -0.9341 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F03 compound treatment 433409.0 -121000.0 -0.88 450594.0 -143000.0 -1.09 -1.3943 -0.9945 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F04 compound treatment 440866.0 -113000.0 -0.83 450630.0 -143000.0 -1.09 -1.3556 -0.9908 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F05 compound treatment 506328.0 -47700.0 -0.35 536244.0 -57800.0 -0.44 -0.5572 -0.9936 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F06 compound treatment 361523.0 -193000.0 -1.41 431551.0 -162000.0 -1.23 -1.8684 -0.9978 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F07 compound treatment 427660.0 -126000.0 -0.92 561159.0 -32800.0 -0.25 -0.8301 -0.8669 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F08 compound treatment 440462.0 -114000.0 -0.83 553743.0 -40300.0 -0.31 -0.8038 -0.9079 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F09 mock treatment 480350.0 -73700.0 -0.54 541552.0 -52500.0 -0.4 -0.663 -0.9889 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F10 mock treatment 501870.0 -52200.0 -0.38 506743.0 -87300.0 -0.66 -0.7387 -0.9656 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F11 compound treatment 429460.0 -125000.0 -0.91 448475.0 -146000.0 -1.11 -1.4261 -0.9954 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F12 compound treatment 478795.0 -75300.0 -0.55 576086.0 -17900.0 -0.14 -0.4855 -0.8562 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F13 compound treatment 129812.0 -424000.0 -3.1 137576.0 -456000.0 -3.47 -4.6457 -0.9985 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F14 compound treatment 551667.0 -2400.0 -0.02 553204.0 -40800.0 -0.31 -0.2316 -0.746 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F15 compound treatment 514924.0 -39100.0 -0.29 537316.0 -56700.0 -0.43 -0.507 -0.9803 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F16 compound treatment 447615.0 -106000.0 -0.78 618414.0 24400.0 0.19 -0.4194 -0.524 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F17 mock treatment 559261.0 5190.0 0.04 621111.0 27100.0 0.21 0.1724 0.8236 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F18 mock treatment 605678.0 51600.0 0.38 546148.0 -47900.0 -0.36 0.0098 0.0187 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F19 compound treatment 481835.0 -72200.0 -0.53 548821.0 -45200.0 -0.34 -0.6163 -0.9782 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F20 compound treatment 617026.0 63000.0 0.46 490158.0 -104000.0 -0.79 -0.2323 -0.2543 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F21 compound treatment 598388.0 44300.0 0.32 558863.0 -35100.0 -0.27 0.0404 0.0962 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F22 compound treatment 414416.0 -140000.0 -1.02 576428.0 -17600.0 -0.13 -0.8166 -0.7928 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F23 compound treatment 434961.0 -119000.0 -0.87 574383.0 -19600.0 -0.15 -0.7213 -0.8162 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 F24 compound treatment 462362.0 -91700.0 -0.67 545066.0 -48900.0 -0.37 -0.7371 -0.9613 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G01 compound treatment 382757.0 -171000.0 -1.25 360157.0 -234000.0 -1.78 -2.1421 -0.9854 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G02 compound treatment 507975.0 -46100.0 -0.34 579952.0 -14100.0 -0.11 -0.3139 -0.8876 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G03 mock treatment 487961.0 -66100.0 -0.48 647994.0 54000.0 0.41 -0.0519 -0.0818 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G04 mock treatment 499502.0 -54600.0 -0.4 584252.0 -9750.0 -0.07 -0.3346 -0.8243 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G05 compound treatment 365755.0 -188000.0 -1.38 413888.0 -180000.0 -1.37 -1.9414 -1.0 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G06 compound treatment 126274.0 -428000.0 -3.13 125442.0 -469000.0 -3.56 -4.7292 -0.9979 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G07 compound treatment 379143.0 -175000.0 -1.28 409386.0 -185000.0 -1.4 -1.8963 -0.9989 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G08 compound treatment 372490.0 -182000.0 -1.33 379354.0 -215000.0 -1.63 -2.092 -0.9948 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G09 compound treatment 138975.0 -415000.0 -3.04 130595.0 -463000.0 -3.52 -4.6358 -0.9973 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G10 compound treatment 330429.0 -224000.0 -1.64 169609.0 -424000.0 -3.22 -3.4362 -0.9505 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G11 compound treatment 143097.0 -411000.0 -3.01 145498.0 -449000.0 -3.41 -4.5345 -0.998 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G12 compound treatment 499721.0 -54400.0 -0.4 552055.0 -41900.0 -0.32 -0.5064 -0.994 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G13 compound treatment 134630.0 -419000.0 -3.07 137878.0 -456000.0 -3.47 -4.6192 -0.9982 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G14 compound treatment 147801.0 -406000.0 -2.97 179175.0 -415000.0 -3.15 -4.3292 -0.9996 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G15 compound treatment 136509.0 -418000.0 -3.05 130826.0 -463000.0 -3.52 -4.6474 -0.9975 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G16 compound treatment 261299.0 -293000.0 -2.14 290883.0 -303000.0 -2.3 -3.1423 -0.9993 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G17 compound treatment 142736.0 -411000.0 -3.01 147435.0 -447000.0 -3.39 -4.5259 -0.9982 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G18 compound treatment 500576.0 -53500.0 -0.39 586701.0 -7300.0 -0.06 -0.3159 -0.7994 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G19 mock treatment 666566.0 112000.0 0.82 628867.0 34900.0 0.26 0.769 0.8898 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G20 mock treatment 509069.0 -45000.0 -0.33 633059.0 39100.0 0.3 -0.0229 -0.0517 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G21 compound treatment 116109.0 -438000.0 -3.2 121759.0 -472000.0 -3.59 -4.8015 -0.9984 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G22 compound treatment 599884.0 45800.0 0.34 653631.0 59600.0 0.45 0.5572 0.989 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G23 compound treatment 527030.0 -27000.0 -0.2 544154.0 -49900.0 -0.38 -0.4076 -0.9541 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 G24 compound treatment 564448.0 10400.0 0.08 535145.0 -58900.0 -0.45 -0.2625 -0.5788 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H01 compound treatment 443872.0 -110000.0 -0.81 505815.0 -88200.0 -0.67 -1.0436 -0.9958 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H02 compound treatment 415105.0 -139000.0 -1.02 473431.0 -121000.0 -0.92 -1.3663 -0.9987 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H03 mock treatment 463084.0 -91000.0 -0.67 647916.0 53900.0 0.41 -0.1809 -0.2315 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H04 mock treatment 445330.0 -109000.0 -0.8 457114.0 -137000.0 -1.04 -1.2977 -0.9912 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H05 compound treatment 466286.0 -87800.0 -0.64 519124.0 -74900.0 -0.57 -0.8562 -0.9982 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H06 compound treatment 520425.0 -33600.0 -0.25 479449.0 -115000.0 -0.87 -0.7894 -0.8728 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H07 compound treatment 475528.0 -78500.0 -0.57 626916.0 32900.0 0.25 -0.2294 -0.3661 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H08 compound treatment 415968.0 -138000.0 -1.01 387317.0 -207000.0 -1.57 -1.8244 -0.9772 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H09 compound treatment 490386.0 -63700.0 -0.47 484277.0 -110000.0 -0.83 -0.9188 -0.9622 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H10 compound treatment 370071.0 -184000.0 -1.35 423114.0 -171000.0 -1.3 -1.8695 -0.9998 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H11 compound treatment 486644.0 -67400.0 -0.49 472861.0 -121000.0 -0.92 -0.9994 -0.9572 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H12 compound treatment 369499.0 -185000.0 -1.35 326441.0 -268000.0 -2.03 -2.3917 -0.9802 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H13 compound treatment 168773.0 -385000.0 -2.82 162391.0 -432000.0 -3.28 -4.311 -0.9972 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H14 compound treatment 281675.0 -272000.0 -1.99 288025.0 -306000.0 -2.32 -3.0522 -0.997 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H15 compound treatment 494889.0 -59200.0 -0.43 544950.0 -49100.0 -0.37 -0.5696 -0.9972 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H16 compound treatment 675373.0 121000.0 0.89 586420.0 -7580.0 -0.06 0.5865 0.6598 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H17 compound treatment 557603.0 3530.0 0.03 480578.0 -113000.0 -0.86 -0.591 -0.6856 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H18 compound treatment 397806.0 -156000.0 -1.14 372653.0 -221000.0 -1.68 -1.9971 -0.9823 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H19 mock treatment 623710.0 69600.0 0.51 632862.0 38900.0 0.3 0.5688 0.9664 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H20 mock treatment 618323.0 64300.0 0.47 491489.0 -103000.0 -0.78 -0.2184 -0.2402 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H21 compound treatment 481167.0 -72900.0 -0.53 412260.0 -182000.0 -1.38 -1.3533 -0.9144 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H22 compound treatment 539874.0 -14200.0 -0.1 650558.0 56600.0 0.43 0.2304 0.5212 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H23 compound treatment 493098.0 -61000.0 -0.45 492513.0 -101000.0 -0.77 -0.8605 -0.9661 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 H24 compound treatment 593093.0 39000.0 0.29 595302.0 1300.0 0.01 0.2088 0.7311 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I01 compound treatment 441313.0 -113000.0 -0.82 493198.0 -101000.0 -0.77 -1.1246 -0.9993 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I02 compound treatment 381725.0 -172000.0 -1.26 395135.0 -199000.0 -1.51 -1.9595 -0.9959 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I03 compound treatment 534486.0 -19600.0 -0.14 621514.0 27500.0 0.21 0.0465 0.1835 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I04 compound treatment 146421.0 -408000.0 -2.98 145894.0 -448000.0 -3.4 -4.5152 -0.9978 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I05 mock treatment 505686.0 -48400.0 -0.35 685345.0 91300.0 0.69 0.2404 0.3087 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I06 mock treatment 495050.0 -59000.0 -0.43 530884.0 -63100.0 -0.48 -0.6443 -0.9986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I07 compound treatment 494848.0 -59200.0 -0.43 522785.0 -71200.0 -0.54 -0.6888 -0.9939 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I08 compound treatment 591311.0 37200.0 0.27 603434.0 9430.0 0.07 0.2432 0.8637 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I09 compound treatment 534708.0 -19400.0 -0.14 656037.0 62000.0 0.47 0.2331 0.4737 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I10 compound treatment 379097.0 -175000.0 -1.28 177137.0 -417000.0 -3.17 -3.1441 -0.9205 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I11 compound treatment 136894.0 -417000.0 -3.05 136909.0 -457000.0 -3.47 -4.6127 -0.9979 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I12 compound treatment 497156.0 -56900.0 -0.42 505674.0 -88300.0 -0.67 -0.7688 -0.9736 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I13 compound treatment 143091.0 -411000.0 -3.01 131221.0 -463000.0 -3.52 -4.6112 -0.997 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I14 compound treatment 221278.0 -333000.0 -2.43 251274.0 -343000.0 -2.6 -3.562 -0.9994 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I15 compound treatment 591791.0 37700.0 0.28 599541.0 5540.0 0.04 0.2248 0.8056 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I16 compound treatment 131905.0 -422000.0 -3.09 133930.0 -460000.0 -3.5 -4.6545 -0.9981 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I17 compound treatment 516726.0 -37300.0 -0.27 527395.0 -66600.0 -0.51 -0.5509 -0.9581 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I18 compound treatment 368448.0 -186000.0 -1.36 414109.0 -180000.0 -1.37 -1.9262 -1.0 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I19 compound treatment 254748.0 -299000.0 -2.19 244665.0 -349000.0 -2.65 -3.4244 -0.9954 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I20 compound treatment 303370.0 -251000.0 -1.83 330965.0 -263000.0 -2.0 -2.7094 -0.9991 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I21 mock treatment 493378.0 -60700.0 -0.44 706967.0 113000.0 0.86 0.2929 0.3032 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I22 mock treatment 547141.0 -6930.0 -0.05 585107.0 -8900.0 -0.07 -0.0836 -0.9899 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I23 compound treatment 122762.0 -431000.0 -3.15 129653.0 -464000.0 -3.53 -4.7247 -0.9984 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 I24 compound treatment 120058.0 -434000.0 -3.17 131419.0 -463000.0 -3.51 -4.7292 -0.9987 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J01 compound treatment 428441.0 -126000.0 -0.92 465371.0 -129000.0 -0.98 -1.3406 -0.9995 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J02 compound treatment 444730.0 -109000.0 -0.8 529776.0 -64200.0 -0.49 -0.9104 -0.9719 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J03 compound treatment 309648.0 -244000.0 -1.79 352735.0 -241000.0 -1.83 -2.56 -0.9999 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J04 compound treatment 464449.0 -89600.0 -0.66 644632.0 50600.0 0.38 -0.1915 -0.252 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J05 mock treatment 504676.0 -49400.0 -0.36 580486.0 -13500.0 -0.1 -0.3281 -0.8735 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J06 mock treatment 419042.0 -135000.0 -0.99 527607.0 -66400.0 -0.5 -1.0549 -0.9514 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J07 compound treatment 483960.0 -70100.0 -0.51 489394.0 -105000.0 -0.79 -0.9245 -0.9775 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J08 compound treatment 286659.0 -267000.0 -1.96 275051.0 -319000.0 -2.42 -3.0962 -0.9944 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J09 compound treatment 537654.0 -16400.0 -0.12 580084.0 -13900.0 -0.11 -0.1597 -0.998 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J10 compound treatment 556523.0 2450.0 0.02 573191.0 -20800.0 -0.16 -0.0991 -0.6229 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J11 compound treatment 406264.0 -148000.0 -1.08 375370.0 -219000.0 -1.66 -1.9388 -0.9784 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J12 compound treatment 345632.0 -208000.0 -1.52 508481.0 -85500.0 -0.65 -1.5373 -0.9277 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J13 compound treatment 528559.0 -25500.0 -0.19 515697.0 -78300.0 -0.59 -0.5526 -0.8863 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J14 compound treatment 558855.0 4780.0 0.03 674333.0 80300.0 0.61 0.4562 0.7464 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J15 compound treatment 455843.0 -98200.0 -0.72 441594.0 -152000.0 -1.16 -1.3267 -0.9736 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J16 compound treatment 474947.0 -79100.0 -0.58 560852.0 -33200.0 -0.25 -0.5873 -0.9306 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J17 compound treatment 147875.0 -406000.0 -2.97 141253.0 -453000.0 -3.44 -4.5326 -0.9973 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J18 compound treatment 473939.0 -80100.0 -0.59 605161.0 11200.0 0.08 -0.3544 -0.5986 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J19 compound treatment 589236.0 35200.0 0.26 626186.0 32200.0 0.24 0.3547 0.9997 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J20 compound treatment 599408.0 45300.0 0.33 519671.0 -74300.0 -0.56 -0.1649 -0.2518 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J21 mock treatment 622730.0 68700.0 0.5 668966.0 75000.0 0.57 0.7577 0.998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J22 mock treatment 547789.0 -6280.0 -0.05 599699.0 5690.0 0.04 -0.0019 -0.0301 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J23 compound treatment 383158.0 -171000.0 -1.25 149727.0 -444000.0 -3.38 -3.2704 -0.9087 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 J24 compound treatment 550268.0 -3800.0 -0.03 588258.0 -5750.0 -0.04 -0.0505 -0.9763 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K01 compound treatment 521586.0 -32500.0 -0.24 622988.0 29000.0 0.22 -0.0123 -0.038 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K02 compound treatment 151365.0 -403000.0 -2.95 122909.0 -471000.0 -3.58 -4.6131 -0.9953 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K03 compound treatment 526588.0 -27500.0 -0.2 645037.0 51000.0 0.39 0.132 0.3023 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K04 compound treatment 258278.0 -296000.0 -2.16 263508.0 -330000.0 -2.51 -3.3049 -0.9972 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K05 compound treatment 550239.0 -3830.0 -0.03 554557.0 -39400.0 -0.3 -0.2317 -0.7699 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K06 compound treatment 134635.0 -419000.0 -3.07 134015.0 -460000.0 -3.49 -4.6399 -0.9979 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K07 mock treatment 557186.0 3110.0 0.02 518491.0 -75500.0 -0.57 -0.3895 -0.6785 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K08 mock treatment 590539.0 36500.0 0.27 663660.0 69700.0 0.53 0.5627 0.9497 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K09 compound treatment 412592.0 -141000.0 -1.03 386239.0 -208000.0 -1.58 -1.8477 -0.979 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K10 compound treatment 527779.0 -26300.0 -0.19 542862.0 -51100.0 -0.39 -0.4107 -0.9474 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K11 compound treatment 135373.0 -419000.0 -3.06 132819.0 -461000.0 -3.5 -4.6425 -0.9977 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K12 compound treatment 133219.0 -421000.0 -3.08 135460.0 -459000.0 -3.48 -4.6395 -0.9981 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K13 compound treatment 623421.0 69300.0 0.51 719169.0 125000.0 0.95 1.031 0.9567 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K14 compound treatment 465724.0 -88300.0 -0.65 506887.0 -87100.0 -0.66 -0.9248 -0.9999 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K15 mock treatment 591454.0 37400.0 0.27 581023.0 -13000.0 -0.1 0.1236 0.4252 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K16 mock treatment 603284.0 49200.0 0.36 685485.0 91500.0 0.69 0.7459 0.9531 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K17 compound treatment 122550.0 -432000.0 -3.16 131499.0 -463000.0 -3.51 -4.7159 -0.9986 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K18 compound treatment 253115.0 -301000.0 -2.2 257650.0 -336000.0 -2.56 -3.3631 -0.9972 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K19 compound treatment 446767.0 -107000.0 -0.78 526693.0 -67300.0 -0.51 -0.9165 -0.9785 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K20 compound treatment 153407.0 -401000.0 -2.93 147050.0 -447000.0 -3.4 -4.4728 -0.9973 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K21 compound treatment 217281.0 -337000.0 -2.46 242283.0 -352000.0 -2.67 -3.631 -0.9992 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K22 compound treatment 159311.0 -395000.0 -2.89 128069.0 -466000.0 -3.54 -4.5442 -0.9949 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K23 mock treatment 547517.0 -6550.0 -0.05 631784.0 37800.0 0.29 0.169 0.581 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 K24 mock treatment 570956.0 16900.0 0.12 564646.0 -29400.0 -0.22 -0.0704 -0.2761 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L01 compound treatment 294963.0 -259000.0 -1.89 241773.0 -352000.0 -2.68 -3.232 -0.9857 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L02 compound treatment 547587.0 -6480.0 -0.05 498312.0 -95700.0 -0.73 -0.5476 -0.7516 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L03 compound treatment 648414.0 94300.0 0.69 670386.0 76400.0 0.58 0.8982 0.9963 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L04 compound treatment 549456.0 -4620.0 -0.03 416850.0 -177000.0 -1.35 -0.9755 -0.7246 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L05 compound treatment 555860.0 1790.0 0.01 673717.0 79700.0 0.61 0.4374 0.7222 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L06 compound treatment 503383.0 -50700.0 -0.37 602180.0 8180.0 0.06 -0.2182 -0.5805 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L07 mock treatment 523134.0 -30900.0 -0.23 585497.0 -8510.0 -0.06 -0.2057 -0.8741 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L08 mock treatment 643060.0 89000.0 0.65 595909.0 1900.0 0.01 0.4704 0.7226 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L09 compound treatment 507744.0 -46300.0 -0.34 426492.0 -168000.0 -1.27 -1.1394 -0.8652 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L10 compound treatment 569543.0 15500.0 0.11 552226.0 -41800.0 -0.32 -0.1444 -0.4286 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L11 compound treatment 547825.0 -6250.0 -0.05 457508.0 -136000.0 -1.04 -0.7655 -0.7375 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L12 compound treatment 541337.0 -12700.0 -0.09 556591.0 -37400.0 -0.28 -0.2668 -0.8921 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L13 compound treatment 550674.0 -3400.0 -0.02 493340.0 -101000.0 -0.76 -0.5583 -0.7297 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L14 compound treatment 566615.0 12500.0 0.09 429143.0 -165000.0 -1.25 -0.8207 -0.6536 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L15 mock treatment 625529.0 71500.0 0.52 684086.0 90100.0 0.68 0.8534 0.9911 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L16 mock treatment 626050.0 72000.0 0.53 694963.0 101000.0 0.77 0.9145 0.9831 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L17 compound treatment 215148.0 -339000.0 -2.48 215410.0 -379000.0 -2.88 -3.7863 -0.9973 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L18 compound treatment 606275.0 52200.0 0.38 566933.0 -27100.0 -0.21 0.1245 0.2872 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L19 compound treatment 478572.0 -75500.0 -0.55 532494.0 -61500.0 -0.47 -0.7208 -0.9966 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L20 compound treatment 716479.0 162000.0 1.19 752283.0 158000.0 1.2 1.6901 1.0 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L21 compound treatment 497233.0 -56800.0 -0.42 623805.0 29800.0 0.23 -0.1338 -0.2828 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L22 compound treatment 647470.0 93400.0 0.68 660585.0 66600.0 0.51 0.8406 0.9891 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L23 mock treatment 619514.0 65400.0 0.48 659600.0 65600.0 0.5 0.6908 0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 L24 mock treatment 573568.0 19500.0 0.14 591291.0 -2710.0 -0.02 0.0862 0.5986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M01 compound treatment 142014.0 -412000.0 -3.01 141471.0 -453000.0 -3.44 -4.5617 -0.9978 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M02 compound treatment 136186.0 -418000.0 -3.06 130754.0 -463000.0 -3.52 -4.6494 -0.9975 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M03 compound treatment 238222.0 -316000.0 -2.31 203309.0 -391000.0 -2.97 -3.732 -0.9923 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M04 compound treatment 136470.0 -418000.0 -3.05 155873.0 -438000.0 -3.33 -4.513 -0.9991 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M05 compound treatment 139031.0 -415000.0 -3.04 142687.0 -451000.0 -3.43 -4.5706 -0.9982 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M06 compound treatment 143122.0 -411000.0 -3.01 137861.0 -456000.0 -3.47 -4.5754 -0.9975 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M07 compound treatment 130384.0 -424000.0 -3.1 130863.0 -463000.0 -3.52 -4.6788 -0.998 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M08 compound treatment 143611.0 -410000.0 -3.0 147578.0 -446000.0 -3.39 -4.5206 -0.9981 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M09 mock treatment 613505.0 59400.0 0.43 549556.0 -44400.0 -0.34 0.0686 0.1246 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M10 mock treatment 595956.0 41900.0 0.31 584779.0 -9230.0 -0.07 0.167 0.5316 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M11 compound treatment 560552.0 6480.0 0.05 691957.0 98000.0 0.74 0.5597 0.7506 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M12 compound treatment 252280.0 -302000.0 -2.21 133576.0 -460000.0 -3.5 -4.0339 -0.9753 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M13 mock treatment 621487.0 67400.0 0.49 646694.0 52700.0 0.4 0.6316 0.9947 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M14 mock treatment 572654.0 18600.0 0.14 582479.0 -11500.0 -0.09 0.0342 0.2114 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M15 compound treatment 557748.0 3680.0 0.03 470577.0 -123000.0 -0.94 -0.644 -0.6865 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M16 compound treatment 136292.0 -418000.0 -3.06 136553.0 -457000.0 -3.48 -4.6177 -0.9979 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M17 compound treatment 391702.0 -162000.0 -1.19 439099.0 -155000.0 -1.18 -1.6717 -1.0 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M18 compound treatment 586550.0 32500.0 0.24 621445.0 27400.0 0.21 0.3154 0.9979 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M19 compound treatment 621008.0 66900.0 0.49 718803.0 125000.0 0.95 1.0165 0.9527 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M20 compound treatment 187506.0 -367000.0 -2.68 135661.0 -458000.0 -3.48 -4.3577 -0.9917 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M21 compound treatment 245062.0 -309000.0 -2.26 262484.0 -332000.0 -2.52 -3.3788 -0.9985 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M22 compound treatment 634189.0 80100.0 0.59 759966.0 166000.0 1.26 1.3058 0.9392 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M23 compound treatment 385004.0 -169000.0 -1.24 364793.0 -229000.0 -1.74 -2.1055 -0.9859 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 M24 compound treatment 128856.0 -425000.0 -3.11 120965.0 -473000.0 -3.59 -4.7399 -0.9974 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N01 compound treatment 497091.0 -57000.0 -0.42 440177.0 -154000.0 -1.17 -1.121 -0.9035 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N02 compound treatment 528969.0 -25100.0 -0.18 622573.0 28600.0 0.22 0.0237 0.0832 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N03 compound treatment 600374.0 46300.0 0.34 725241.0 131000.0 1.0 0.9444 0.8969 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N04 compound treatment 570556.0 16500.0 0.12 688642.0 94600.0 0.72 0.5936 0.8143 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N05 compound treatment 681314.0 127000.0 0.93 732728.0 139000.0 1.05 1.4032 0.9981 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N06 compound treatment 462136.0 -91900.0 -0.67 673495.0 79500.0 0.6 -0.0484 -0.0536 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N07 compound treatment 477976.0 -76100.0 -0.56 518196.0 -75800.0 -0.58 -0.8007 -0.9999 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N08 compound treatment 571422.0 17400.0 0.13 591408.0 -2600.0 -0.02 0.0758 0.5901 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N09 mock treatment 552138.0 -1930.0 -0.01 595721.0 1720.0 0.01 -8.0E-4 -0.0405 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N10 mock treatment 522395.0 -31700.0 -0.23 590077.0 -3930.0 -0.03 -0.1849 -0.7916 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N11 compound treatment 509716.0 -44400.0 -0.32 553722.0 -40300.0 -0.31 -0.4458 -0.9996 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N12 compound treatment 603171.0 49100.0 0.36 486802.0 -107000.0 -0.81 -0.322 -0.3617 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N13 mock treatment 688052.0 134000.0 0.98 566388.0 -27600.0 -0.21 0.5445 0.5434 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N14 mock treatment 584876.0 30800.0 0.23 535800.0 -58200.0 -0.44 -0.1534 -0.3091 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N15 compound treatment 570792.0 16700.0 0.12 489417.0 -105000.0 -0.79 -0.4754 -0.5913 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N16 compound treatment 589404.0 35300.0 0.26 675220.0 81200.0 0.62 0.619 0.9254 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N17 compound treatment 177595.0 -376000.0 -2.75 181758.0 -412000.0 -3.13 -4.1613 -0.9979 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N18 compound treatment 608902.0 54800.0 0.4 657285.0 63300.0 0.48 0.6235 0.9959 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N19 compound treatment 652455.0 98400.0 0.72 549383.0 -44600.0 -0.34 0.2691 0.3383 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N20 compound treatment 592209.0 38100.0 0.28 739809.0 146000.0 1.11 0.9804 0.8584 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N21 compound treatment 550254.0 -3820.0 -0.03 578017.0 -16000.0 -0.12 -0.1056 -0.8475 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N22 compound treatment 539447.0 -14600.0 -0.11 442597.0 -151000.0 -1.15 -0.8889 -0.7695 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N23 compound treatment 541249.0 -12800.0 -0.09 485816.0 -108000.0 -0.82 -0.6475 -0.7827 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 N24 compound treatment 652395.0 98300.0 0.72 668173.0 74200.0 0.56 0.9069 0.9927 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O01 compound treatment 595691.0 41600.0 0.3 670810.0 76800.0 0.58 0.6278 0.954 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O02 compound treatment 238612.0 -315000.0 -2.31 185137.0 -409000.0 -3.11 -3.8276 -0.9893 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O03 compound treatment 552978.0 -1090.0 -0.01 506962.0 -87000.0 -0.66 -0.4732 -0.7156 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O04 compound treatment 144697.0 -409000.0 -2.99 146825.0 -447000.0 -3.4 -4.5191 -0.998 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O05 compound treatment 137363.0 -417000.0 -3.05 130455.0 -464000.0 -3.52 -4.6449 -0.9974 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O06 compound treatment 132696.0 -421000.0 -3.08 136961.0 -457000.0 -3.47 -4.6341 -0.9982 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O07 compound treatment 152308.0 -402000.0 -2.94 215543.0 -378000.0 -2.88 -4.1106 -0.9999 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O08 compound treatment 437458.0 -117000.0 -0.85 496722.0 -97300.0 -0.74 -1.1256 -0.9975 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O09 compound treatment 206405.0 -348000.0 -2.54 161812.0 -432000.0 -3.28 -4.1195 -0.992 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O10 compound treatment 609601.0 55500.0 0.41 587835.0 -6170.0 -0.05 0.254 0.6214 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O11 mock treatment 637510.0 83400.0 0.61 538470.0 -55500.0 -0.42 0.1332 0.1795 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O12 mock treatment 626126.0 72100.0 0.53 685581.0 91600.0 0.7 0.8645 0.9906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O13 compound treatment 439086.0 -115000.0 -0.84 521781.0 -72200.0 -0.55 -0.9826 -0.9786 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O14 compound treatment 335505.0 -219000.0 -1.6 260258.0 -334000.0 -2.54 -2.923 -0.9753 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O15 compound treatment 139472.0 -415000.0 -3.03 144489.0 -450000.0 -3.41 -4.5586 -0.9982 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O16 compound treatment 449796.0 -104000.0 -0.76 346176.0 -248000.0 -1.88 -1.8705 -0.9208 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O17 compound treatment 250246.0 -304000.0 -2.22 267296.0 -327000.0 -2.48 -3.3261 -0.9985 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O18 compound treatment 287693.0 -266000.0 -1.95 176205.0 -418000.0 -3.17 -3.6218 -0.9725 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O19 compound treatment 155515.0 -399000.0 -2.91 159666.0 -434000.0 -3.3 -4.3941 -0.9981 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O20 compound treatment 513291.0 -40800.0 -0.3 568662.0 -25300.0 -0.19 -0.347 -0.9776 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O21 compound treatment 183736.0 -370000.0 -2.71 183528.0 -410000.0 -3.12 -4.12 -0.9975 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O22 compound treatment 118839.0 -435000.0 -3.18 126298.0 -468000.0 -3.55 -4.763 -0.9985 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O23 compound treatment 116545.0 -438000.0 -3.2 123391.0 -471000.0 -3.58 -4.7905 -0.9985 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 O24 compound treatment 464975.0 -89100.0 -0.65 497370.0 -96600.0 -0.73 -0.9798 -0.9982 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P01 compound treatment 647969.0 93900.0 0.69 687700.0 93700.0 0.71 0.9889 0.9998 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P02 compound treatment 586848.0 32800.0 0.24 679394.0 85400.0 0.65 0.6282 0.9084 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P03 compound treatment 588970.0 34900.0 0.26 663283.0 69300.0 0.53 0.5526 0.9448 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P04 compound treatment 488772.0 -65300.0 -0.48 571090.0 -22900.0 -0.17 -0.4608 -0.9065 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P05 compound treatment 123837.0 -430000.0 -3.15 129000.0 -465000.0 -3.53 -4.7227 -0.9983 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P06 compound treatment 616946.0 62900.0 0.46 662339.0 68300.0 0.52 0.6922 0.9982 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P07 compound treatment 723427.0 169000.0 1.24 723461.0 129000.0 0.98 1.5712 0.9935 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P08 compound treatment 615127.0 61100.0 0.45 634132.0 40100.0 0.3 0.5313 0.9827 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P09 compound treatment 509929.0 -44100.0 -0.32 421031.0 -173000.0 -1.31 -1.1574 -0.8554 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P10 compound treatment 555008.0 936.0 0.01 505632.0 -88400.0 -0.67 -0.4699 -0.6999 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P11 mock treatment 635197.0 81100.0 0.59 597518.0 3510.0 0.03 0.4384 0.7382 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P12 mock treatment 634566.0 80500.0 0.59 610179.0 16200.0 0.12 0.5031 0.8367 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P13 compound treatment 414977.0 -139000.0 -1.02 447767.0 -146000.0 -1.11 -1.5048 -0.999 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P14 compound treatment 645967.0 91900.0 0.67 732766.0 139000.0 1.05 1.2206 0.9764 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P15 compound treatment 491379.0 -62700.0 -0.46 395242.0 -199000.0 -1.51 -1.3919 -0.882 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P16 compound treatment 720165.0 166000.0 1.21 597256.0 3250.0 0.02 0.8764 0.7213 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P17 compound treatment 397189.0 -157000.0 -1.15 333419.0 -261000.0 -1.98 -2.2111 -0.9664 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P18 compound treatment 565796.0 11700.0 0.09 556593.0 -37400.0 -0.28 -0.1403 -0.4727 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P19 compound treatment 708187.0 154000.0 1.13 633796.0 39800.0 0.3 1.0107 0.8661 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P20 compound treatment 663563.0 109000.0 0.8 629393.0 35400.0 0.27 0.7563 0.8954 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P21 compound treatment 631795.0 77700.0 0.57 659234.0 65200.0 0.5 0.7523 0.9977 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P22 compound treatment 623316.0 69200.0 0.51 691840.0 97800.0 0.74 0.8836 0.9825 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P23 compound treatment 138771.0 -415000.0 -3.04 156596.0 -437000.0 -3.32 -4.4972 -0.999 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2102 P24 compound treatment 681084.0 127000.0 0.93 692244.0 98200.0 0.75 1.1845 0.9941 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A01 compound treatment 623485.0 24900.0 0.18 605565.0 -38500.0 -0.29 -0.0781 -0.2266 3070297 PK04_103001 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A02 compound treatment 620939.0 22400.0 0.16 637956.0 -6130.0 -0.05 0.0827 0.4866 3189402 PK04_103002 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A03 compound treatment 510297.0 -88300.0 -0.65 501106.0 -143000.0 -1.09 -1.2245 -0.9691 3070298 PK04_103003 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A04 compound treatment 521890.0 -76700.0 -0.56 561114.0 -83000.0 -0.63 -0.8422 -0.9983 3189403 PK04_103004 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A05 compound treatment 521541.0 -77000.0 -0.56 536951.0 -107000.0 -0.81 -0.9738 -0.9839 3070299 PK04_103005 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A06 compound treatment 586148.0 -12400.0 -0.09 605086.0 -39000.0 -0.3 -0.2737 -0.8834 3189404 PK04_103006 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A07 compound treatment 509898.0 -88700.0 -0.65 563891.0 -80200.0 -0.61 -0.8893 -0.9995 3070300 PK04_103007 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A08 compound treatment 539639.0 -58900.0 -0.43 560489.0 -83600.0 -0.64 -0.7538 -0.9822 3189405 PK04_103008 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A09 compound treatment 525249.0 -73300.0 -0.54 532426.0 -112000.0 -0.85 -0.979 -0.9755 3189406 PK04_103009 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A10 compound treatment 534600.0 -64000.0 -0.47 593369.0 -50700.0 -0.39 -0.6032 -0.9953 3070355 PK04_103010 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A11 compound treatment 530049.0 -68500.0 -0.5 688514.0 44400.0 0.34 -0.1157 -0.1915 3189407 PK04_103011 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A12 compound treatment 561224.0 -37400.0 -0.27 528906.0 -115000.0 -0.87 -0.8118 -0.8857 3189408 PK04_103012 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A13 mock treatment 576606.0 -22000.0 -0.16 540532.0 -104000.0 -0.79 -0.6699 -0.8343 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A14 mock treatment 579781.0 -18800.0 -0.14 509615.0 -134000.0 -1.02 -0.8195 -0.7951 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A15 compound treatment 553716.0 -44900.0 -0.33 554585.0 -89500.0 -0.68 -0.7127 -0.9441 3070356 PK04_103013 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A16 compound treatment 551632.0 -46900.0 -0.34 524040.0 -120000.0 -0.91 -0.8876 -0.9109 3189409 PK04_103014 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A17 compound treatment 326700.0 -272000.0 -1.99 339583.0 -304000.0 -2.31 -3.0416 -0.9972 3070357 PK04_103015 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A18 compound treatment 590725.0 -7850.0 -0.06 534402.0 -110000.0 -0.83 -0.6298 -0.754 3189410 PK04_103016 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A19 compound treatment 544376.0 -54200.0 -0.4 566143.0 -77900.0 -0.59 -0.6989 -0.981 3070358 PK04_103017 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A20 compound treatment 553832.0 -44700.0 -0.33 567190.0 -76900.0 -0.58 -0.6444 -0.9625 3189411 PK04_103018 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A21 compound treatment 560888.0 -37700.0 -0.28 573176.0 -70900.0 -0.54 -0.5758 -0.9516 3070359 PK04_103019 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A22 compound treatment 570890.0 -27700.0 -0.2 592952.0 -51100.0 -0.39 -0.4178 -0.9539 3189412 PK04_103020 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A23 compound treatment 501742.0 -96800.0 -0.71 525834.0 -118000.0 -0.9 -1.1359 -0.9931 3070360 PK04_103021 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 A24 compound treatment 378995.0 -220000.0 -1.61 454698.0 -189000.0 -1.44 -2.1528 -0.9985 3189413 PK04_103022 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B01 compound treatment 646272.0 47700.0 0.35 618495.0 -25600.0 -0.19 0.1092 0.2735 3189525 PK04_103023 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B02 compound treatment 493369.0 -105000.0 -0.77 630504.0 -13600.0 -0.1 -0.617 -0.7948 3070361 PK04_103024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B03 compound treatment 602212.0 3640.0 0.03 637759.0 -6320.0 -0.05 -0.0152 -0.2762 3189526 PK04_103025 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B04 compound treatment 579640.0 -18900.0 -0.14 599825.0 -44300.0 -0.34 -0.3357 -0.9231 3189527 PK04_103026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B05 compound treatment 683047.0 84500.0 0.62 604424.0 -39700.0 -0.3 0.2238 0.3256 3070362 PK04_103027 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B06 compound treatment 527725.0 -70900.0 -0.52 663380.0 19300.0 0.15 -0.2627 -0.4879 3189528 PK04_103028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B07 compound treatment 583117.0 -15500.0 -0.11 527783.0 -116000.0 -0.88 -0.7047 -0.7911 3070363 PK04_103029 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B08 compound treatment 570103.0 -28500.0 -0.21 522735.0 -121000.0 -0.92 -0.7991 -0.8455 3189529 PK04_103030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B09 compound treatment 554110.0 -44500.0 -0.33 547473.0 -96600.0 -0.73 -0.7489 -0.9329 3189530 PK04_103031 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B10 compound treatment 552465.0 -46100.0 -0.34 513406.0 -131000.0 -0.99 -0.9404 -0.897 3070364 PK04_103032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B11 compound treatment 581691.0 -16900.0 -0.12 512398.0 -132000.0 -1.0 -0.7947 -0.7884 3189531 PK04_103033 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B12 compound treatment 579573.0 -19000.0 -0.14 597174.0 -46900.0 -0.36 -0.3502 -0.9157 3189532 PK04_103034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B13 mock treatment 592539.0 -6040.0 -0.04 639302.0 -4780.0 -0.04 -0.0569 -0.9953 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B14 mock treatment 501550.0 -97000.0 -0.71 528534.0 -116000.0 -0.88 -1.1224 -0.9944 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B15 compound treatment 564453.0 -34100.0 -0.25 627041.0 -17000.0 -0.13 -0.268 -0.9533 3070365 PK04_103035 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B16 compound treatment 534593.0 -64000.0 -0.47 562398.0 -81700.0 -0.62 -0.7697 -0.9903 3189533 PK04_103036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B17 compound treatment 612601.0 14000.0 0.1 622754.0 -21300.0 -0.16 -0.042 -0.2193 3070366 PK04_103037 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B18 compound treatment 578479.0 -20100.0 -0.15 653915.0 9830.0 0.07 -0.0511 -0.31 3189534 PK04_103038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B19 compound treatment 500507.0 -98100.0 -0.72 539418.0 -105000.0 -0.8 -1.0694 -0.9987 3189535 PK04_103039 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B20 compound treatment 562181.0 -36400.0 -0.27 604861.0 -39200.0 -0.3 -0.3989 -0.9984 3070367 PK04_103040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B21 compound treatment 540563.0 -58000.0 -0.42 540619.0 -103000.0 -0.79 -0.8558 -0.9581 3189536 PK04_103041 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B22 compound treatment 614897.0 16300.0 0.12 663042.0 19000.0 0.14 0.1862 0.9956 3189537 PK04_103042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B23 compound treatment 503489.0 -95100.0 -0.7 665810.0 21700.0 0.17 -0.375 -0.5247 3070368 PK04_103043 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 B24 compound treatment 565717.0 -32900.0 -0.24 658591.0 14500.0 0.11 -0.092 -0.3479 3189538 PK04_103044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C01 compound treatment 593431.0 -5150.0 -0.04 540652.0 -103000.0 -0.79 -0.5822 -0.7401 3070369 PK04_103045 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C02 compound treatment 556110.0 -42500.0 -0.31 605461.0 -38600.0 -0.29 -0.4271 -0.9996 3189539 PK04_103046 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C03 compound treatment 541466.0 -57100.0 -0.42 596851.0 -47200.0 -0.36 -0.549 -0.9971 3189540 PK04_103047 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C04 compound treatment 580669.0 -17900.0 -0.13 613451.0 -30600.0 -0.23 -0.2571 -0.963 3070370 PK04_103048 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C05 compound treatment 529356.0 -69200.0 -0.51 588042.0 -56000.0 -0.43 -0.659 -0.9963 3189541 PK04_103049 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C06 compound treatment 559214.0 -39400.0 -0.29 499337.0 -145000.0 -1.1 -0.9811 -0.8631 3189542 PK04_103050 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C07 compound treatment 519504.0 -79100.0 -0.58 603602.0 -40500.0 -0.31 -0.6263 -0.9563 3070371 PK04_103051 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C08 compound treatment 503794.0 -94800.0 -0.69 522044.0 -122000.0 -0.93 -1.1457 -0.9897 3189543 PK04_103052 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C09 compound treatment 530460.0 -68100.0 -0.5 573746.0 -70300.0 -0.53 -0.7301 -0.9994 3070372 PK04_103053 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C10 compound treatment 562240.0 -36300.0 -0.27 553001.0 -91100.0 -0.69 -0.6772 -0.9136 3189544 PK04_103054 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C11 mock treatment 565441.0 -33100.0 -0.24 618080.0 -26000.0 -0.2 -0.311 -0.9949 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C12 mock treatment 620179.0 21600.0 0.16 581995.0 -62100.0 -0.47 -0.2218 -0.4459 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C13 compound treatment 480142.0 -118000.0 -0.87 664628.0 20500.0 0.16 -0.5021 -0.5705 3189545 PK04_103055 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C14 compound treatment 593835.0 -4740.0 -0.03 639867.0 -4210.0 -0.03 -0.0472 -0.9992 3189546 PK04_103056 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C15 mock treatment 550161.0 -48400.0 -0.35 594758.0 -49300.0 -0.37 -0.5153 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C16 mock treatment 573247.0 -25300.0 -0.19 651917.0 7840.0 0.06 -0.0889 -0.4569 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C17 compound treatment 496786.0 -102000.0 -0.74 354852.0 -289000.0 -2.2 -2.08 -0.8966 3070427 PK04_103057 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C18 compound treatment 583155.0 -15400.0 -0.11 607769.0 -36300.0 -0.28 -0.2748 -0.9221 3189660 PK04_103058 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C19 compound treatment 521645.0 -76900.0 -0.56 593623.0 -50500.0 -0.38 -0.6689 -0.9825 3070428 PK04_103059 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C20 compound treatment 591397.0 -7180.0 -0.05 533821.0 -110000.0 -0.84 -0.6294 -0.75 3189661 PK04_103060 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C21 compound treatment 586921.0 -11700.0 -0.09 702825.0 58700.0 0.45 0.2553 0.5619 3189662 PK04_103061 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C22 compound treatment 568630.0 -29900.0 -0.22 666345.0 22300.0 0.17 -0.0353 -0.1274 3070429 PK04_103062 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C23 compound treatment 485844.0 -113000.0 -0.82 580014.0 -64100.0 -0.49 -0.9271 -0.9684 3189663 PK04_103063 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 C24 compound treatment 543311.0 -55300.0 -0.4 564802.0 -79300.0 -0.6 -0.7117 -0.9812 3189664 PK04_103064 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D01 compound treatment 604115.0 5540.0 0.04 549855.0 -94200.0 -0.72 -0.4775 -0.666 3070430 PK04_103065 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D02 compound treatment 119843.0 -479000.0 -3.5 123880.0 -520000.0 -3.95 -5.27 -0.9982 3189665 PK04_103066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D03 compound treatment 596624.0 -1950.0 -0.01 637299.0 -6780.0 -0.05 -0.0465 -0.8703 3070431 PK04_103067 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D04 compound treatment 470920.0 -128000.0 -0.93 549956.0 -94100.0 -0.72 -1.1657 -0.9913 3189666 PK04_103068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D05 compound treatment 495359.0 -103000.0 -0.75 616742.0 -27300.0 -0.21 -0.6806 -0.8694 3189667 PK04_103069 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D06 compound treatment 499620.0 -99000.0 -0.72 551454.0 -92600.0 -0.7 -1.0093 -0.9999 3189668 PK04_103070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D07 compound treatment 601024.0 2450.0 0.02 657655.0 13600.0 0.1 0.0856 0.8176 3070432 PK04_103071 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D08 compound treatment 570708.0 -27900.0 -0.2 537408.0 -107000.0 -0.81 -0.7171 -0.8582 3189669 PK04_103072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D09 compound treatment 547407.0 -51200.0 -0.37 501294.0 -143000.0 -1.08 -1.0316 -0.8991 3070433 PK04_103073 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D10 compound treatment 595204.0 -3370.0 -0.02 531345.0 -113000.0 -0.86 -0.623 -0.7272 3189670 PK04_103074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D11 mock treatment 579396.0 -19200.0 -0.14 587303.0 -56800.0 -0.43 -0.4042 -0.8911 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D12 mock treatment 502934.0 -95600.0 -0.7 623771.0 -20300.0 -0.15 -0.6037 -0.8428 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D13 compound treatment 546340.0 -52200.0 -0.38 664907.0 20800.0 0.16 -0.1583 -0.3827 3189671 PK04_103075 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D14 compound treatment 586958.0 -11600.0 -0.08 582881.0 -61200.0 -0.46 -0.3888 -0.8227 3070434 PK04_103076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D15 mock treatment 570981.0 -27600.0 -0.2 705101.0 61000.0 0.46 0.1851 0.3661 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D16 mock treatment 497080.0 -101000.0 -0.74 636471.0 -7610.0 -0.06 -0.5657 -0.7599 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D17 compound treatment 320257.0 -278000.0 -2.04 325555.0 -319000.0 -2.42 -3.1503 -0.9963 3189672 PK04_103077 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D18 compound treatment 547201.0 -51400.0 -0.38 619109.0 -25000.0 -0.19 -0.3998 -0.9499 3189673 PK04_103078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D19 compound treatment 579533.0 -19000.0 -0.14 603534.0 -40500.0 -0.31 -0.3163 -0.9356 3070435 PK04_103079 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D20 compound treatment 517894.0 -80700.0 -0.59 600701.0 -43400.0 -0.33 -0.6503 -0.9621 3189674 PK04_103080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D21 compound treatment 523901.0 -74700.0 -0.55 663057.0 19000.0 0.14 -0.2842 -0.5032 3189675 PK04_103081 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D22 compound treatment 576757.0 -21800.0 -0.16 701833.0 57800.0 0.44 0.1974 0.4228 3070436 PK04_103082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D23 compound treatment 483869.0 -115000.0 -0.84 569581.0 -74500.0 -0.57 -0.9934 -0.9816 3189676 PK04_103083 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 D24 compound treatment 486548.0 -112000.0 -0.82 588244.0 -55800.0 -0.42 -0.8793 -0.953 3070437 PK04_103084 CN1CCC(=CC1C2CC2)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E01 mock treatment 538568.0 -60000.0 -0.44 642060.0 -2020.0 -0.02 -0.3212 -0.7314 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E02 mock treatment 607340.0 8760.0 0.06 513135.0 -131000.0 -0.99 -0.6581 -0.6602 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E03 compound treatment 563315.0 -35300.0 -0.26 517504.0 -127000.0 -0.96 -0.8623 -0.8661 3189677 PK04_103085 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E04 compound treatment 478856.0 -120000.0 -0.88 628991.0 -15100.0 -0.11 -0.7002 -0.7929 3070438 PK04_103086 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E05 compound treatment 510298.0 -88300.0 -0.65 655411.0 11300.0 0.09 -0.3956 -0.6075 3189678 PK04_103087 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E06 compound treatment 619366.0 20800.0 0.15 681890.0 37800.0 0.29 0.3106 0.9558 3189679 PK04_103088 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E07 compound treatment 520397.0 -78200.0 -0.57 535961.0 -108000.0 -0.82 -0.9851 -0.9843 3189680 PK04_103089 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E08 compound treatment 466912.0 -132000.0 -0.96 633470.0 -10600.0 -0.08 -0.7379 -0.7636 3070490 PK04_103090 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E09 mock treatment 504138.0 -94400.0 -0.69 590476.0 -53600.0 -0.41 -0.7763 -0.9683 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E10 mock treatment 506598.0 -92000.0 -0.67 614176.0 -29900.0 -0.23 -0.6363 -0.8962 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E11 compound treatment 522570.0 -76000.0 -0.56 628278.0 -15800.0 -0.12 -0.4779 -0.8405 3187704 PK04_103091 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E12 compound treatment 578185.0 -20400.0 -0.15 704352.0 60300.0 0.46 0.2183 0.4534 3070491 PK04_103092 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E13 compound treatment 570474.0 -28100.0 -0.21 518023.0 -126000.0 -0.96 -0.8225 -0.8397 3187705 PK04_103093 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E14 compound treatment 561933.0 -36600.0 -0.27 697677.0 53600.0 0.41 0.0984 0.2019 3187706 PK04_103094 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E15 compound treatment 561413.0 -37200.0 -0.27 706439.0 62400.0 0.47 0.1428 0.2614 3070492 PK04_103095 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E16 compound treatment 644024.0 45400.0 0.33 685090.0 41000.0 0.31 0.4553 0.9995 3187707 PK04_103096 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E17 mock treatment 636530.0 38000.0 0.28 636348.0 -7730.0 -0.06 0.1547 0.5454 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E18 mock treatment 561943.0 -36600.0 -0.27 594490.0 -49600.0 -0.38 -0.4558 -0.986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E19 compound treatment 679317.0 80700.0 0.59 625083.0 -19000.0 -0.14 0.3155 0.519 3070493 PK04_103097 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E20 compound treatment 512282.0 -86300.0 -0.63 730524.0 86400.0 0.66 0.0181 0.0199 3187708 PK04_103098 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E21 compound treatment 544285.0 -54300.0 -0.4 618299.0 -25800.0 -0.2 -0.4192 -0.947 3187709 PK04_103099 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E22 compound treatment 629673.0 31100.0 0.23 670270.0 26200.0 0.2 0.3015 0.9978 3070494 PK04_103100 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E23 compound treatment 469129.0 -129000.0 -0.95 511485.0 -133000.0 -1.01 -1.3817 -0.9995 3187710 PK04_103101 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 E24 compound treatment 586664.0 -11900.0 -0.09 629359.0 -14700.0 -0.11 -0.1407 -0.9924 3187711 PK04_103102 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F01 mock treatment 499493.0 -99100.0 -0.72 662055.0 18000.0 0.14 -0.4158 -0.5639 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F02 mock treatment 613305.0 14700.0 0.11 633255.0 -10800.0 -0.08 0.018 0.1329 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F03 compound treatment 510810.0 -87800.0 -0.64 615610.0 -28500.0 -0.22 -0.6068 -0.8959 3070495 PK04_103103 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F04 compound treatment 607728.0 9150.0 0.07 738098.0 94000.0 0.71 0.5524 0.77 3187712 PK04_103104 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F05 compound treatment 549647.0 -48900.0 -0.36 609383.0 -34700.0 -0.26 -0.4394 -0.9887 3070496 PK04_103105 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F06 compound treatment 589746.0 -8830.0 -0.06 623276.0 -20800.0 -0.16 -0.1574 -0.922 3187713 PK04_103106 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F07 compound treatment 584878.0 -13700.0 -0.1 691725.0 47600.0 0.36 0.1851 0.4929 3070497 PK04_103107 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F08 compound treatment 596195.0 -2380.0 -0.02 649484.0 5400.0 0.04 0.0167 0.3747 3187714 PK04_103108 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F09 mock treatment 542738.0 -55800.0 -0.41 655883.0 11800.0 0.09 -0.2254 -0.539 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F10 mock treatment 547674.0 -50900.0 -0.37 648623.0 4540.0 0.03 -0.2388 -0.6388 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F11 compound treatment 560744.0 -37800.0 -0.28 597540.0 -46500.0 -0.35 -0.4456 -0.9926 3187715 PK04_103109 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F12 compound treatment 558046.0 -40500.0 -0.3 658929.0 14800.0 0.11 -0.1298 -0.4094 3070498 PK04_103110 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F13 compound treatment 359803.0 -239000.0 -1.75 417431.0 -227000.0 -1.72 -2.4522 -1.0 3187716 PK04_103111 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F14 compound treatment 524031.0 -74500.0 -0.55 687322.0 43200.0 0.33 -0.1532 -0.2407 3070499 PK04_103112 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F15 compound treatment 549852.0 -48700.0 -0.36 625609.0 -18500.0 -0.14 -0.3512 -0.917 3187717 PK04_103113 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F16 compound treatment 522011.0 -76600.0 -0.56 699351.0 55300.0 0.42 -0.099 -0.1415 3187718 PK04_103114 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F17 mock treatment 540238.0 -58300.0 -0.43 684518.0 40400.0 0.31 -0.0845 -0.1607 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F18 mock treatment 543080.0 -55500.0 -0.41 753533.0 109000.0 0.83 0.301 0.3253 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F19 compound treatment 587608.0 -11000.0 -0.08 580118.0 -64000.0 -0.49 -0.4003 -0.8128 3070500 PK04_103115 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F20 compound treatment 589494.0 -9080.0 -0.07 692294.0 48200.0 0.37 0.212 0.5696 3187719 PK04_103116 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F21 compound treatment 537486.0 -61100.0 -0.45 602425.0 -41700.0 -0.32 -0.5397 -0.9857 3070501 PK04_103117 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F22 compound treatment 561999.0 -36600.0 -0.27 618253.0 -25800.0 -0.2 -0.3279 -0.9884 3187720 PK04_103118 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F23 compound treatment 467608.0 -131000.0 -0.96 602699.0 -41400.0 -0.31 -0.8996 -0.8924 3187721 PK04_103119 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 F24 compound treatment 496878.0 -102000.0 -0.74 641022.0 -3060.0 -0.02 -0.5423 -0.7288 3070502 PK04_103120 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G01 compound treatment 531160.0 -67400.0 -0.49 585421.0 -58700.0 -0.45 -0.6637 -0.9987 3187722 PK04_103121 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G02 compound treatment 603230.0 4650.0 0.03 510638.0 -133000.0 -1.01 -0.6928 -0.683 3187723 PK04_103122 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G03 mock treatment 615341.0 16800.0 0.12 563228.0 -80900.0 -0.61 -0.3476 -0.555 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G04 mock treatment 510136.0 -88400.0 -0.65 565969.0 -78100.0 -0.59 -0.8769 -0.9991 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G05 compound treatment 494185.0 -104000.0 -0.76 564630.0 -79500.0 -0.6 -0.9666 -0.9932 3070503 PK04_103123 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G06 compound treatment 568949.0 -29600.0 -0.22 589891.0 -54200.0 -0.41 -0.4443 -0.9551 3187724 PK04_103124 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G07 compound treatment 411377.0 -187000.0 -1.37 593265.0 -50800.0 -0.39 -1.241 -0.8725 3070504 PK04_103125 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G08 compound treatment 641446.0 42900.0 0.31 616257.0 -27800.0 -0.21 0.0722 0.191 3187725 PK04_103126 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G09 compound treatment 529285.0 -69300.0 -0.51 725078.0 81000.0 0.62 0.0768 0.0963 3187726 PK04_103127 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G10 compound treatment 599671.0 1090.0 0.01 754024.0 110000.0 0.84 0.5962 0.7138 3070543 PK04_103128 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G11 compound treatment 570527.0 -28000.0 -0.21 545312.0 -98800.0 -0.75 -0.6756 -0.8685 3187727 PK04_103129 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G12 compound treatment 323812.0 -275000.0 -2.01 317546.0 -327000.0 -2.48 -3.1749 -0.9945 3187844 PK04_103130 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G13 compound treatment 591642.0 -6930.0 -0.05 552154.0 -91900.0 -0.7 -0.5297 -0.7565 3070544 PK04_103131 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G14 compound treatment 592456.0 -6120.0 -0.04 665146.0 21100.0 0.16 0.0815 0.4905 3187845 PK04_103132 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G15 compound treatment 646440.0 47900.0 0.35 739636.0 95600.0 0.73 0.7608 0.944 3070545 PK04_103133 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G16 compound treatment 596157.0 -2420.0 -0.02 589916.0 -54200.0 -0.41 -0.3035 -0.7368 3187846 PK04_103134 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G17 compound treatment 602839.0 4260.0 0.03 658717.0 14600.0 0.11 0.1007 0.8717 3070546 PK04_103135 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G18 compound treatment 558715.0 -39900.0 -0.29 687172.0 43100.0 0.33 0.0253 0.0578 3187847 PK04_103136 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G19 mock treatment 548978.0 -49600.0 -0.36 778427.0 134000.0 1.02 0.4652 0.4295 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G20 mock treatment 608733.0 10200.0 0.07 687735.0 43700.0 0.33 0.287 0.8446 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G21 compound treatment 524430.0 -74100.0 -0.54 606268.0 -37800.0 -0.29 -0.5865 -0.9559 3070547 PK04_103137 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G22 compound treatment 608035.0 9460.0 0.07 637587.0 -6490.0 -0.05 0.014 0.1651 3187848 PK04_103138 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G23 compound treatment 490275.0 -108000.0 -0.79 619431.0 -24700.0 -0.19 -0.6925 -0.8508 3070548 PK04_103139 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 G24 compound treatment 503465.0 -95100.0 -0.7 557538.0 -86500.0 -0.66 -0.9567 -0.9996 3187849 PK04_103140 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H01 compound treatment 486803.0 -112000.0 -0.82 639875.0 -4210.0 -0.03 -0.6006 -0.7342 3070549 PK04_103141 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H02 compound treatment 665606.0 67000.0 0.49 659670.0 15600.0 0.12 0.4304 0.8534 3187850 PK04_103142 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H03 mock treatment 660428.0 61900.0 0.45 660664.0 16600.0 0.13 0.4089 0.8709 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H04 mock treatment 620354.0 21800.0 0.16 593892.0 -50200.0 -0.38 -0.157 -0.3799 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H05 compound treatment 585508.0 -13100.0 -0.1 602119.0 -42000.0 -0.32 -0.293 -0.8804 3187851 PK04_103143 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H06 compound treatment 487945.0 -111000.0 -0.81 684060.0 40000.0 0.3 -0.3573 -0.4135 3187852 PK04_103144 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H07 compound treatment 494917.0 -104000.0 -0.76 695237.0 51200.0 0.39 -0.2612 -0.3067 3070550 PK04_103145 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H08 compound treatment 583290.0 -15300.0 -0.11 694579.0 50500.0 0.38 0.1922 0.481 3187853 PK04_103146 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H09 compound treatment 689208.0 90600.0 0.66 644838.0 757.0 0.01 0.4727 0.7132 3070551 PK04_103147 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H10 compound treatment 681055.0 82500.0 0.6 622694.0 -21400.0 -0.16 0.3116 0.4989 3070552 PK04_103148 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H11 compound treatment 670749.0 72200.0 0.53 670563.0 26500.0 0.2 0.5155 0.9126 3187854 PK04_103149 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H12 compound treatment 620457.0 21900.0 0.16 691702.0 47600.0 0.36 0.369 0.9327 3070553 PK04_103150 CN1CCC(=CC1c2cccs2)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H13 compound treatment 585843.0 -12700.0 -0.09 778049.0 134000.0 1.02 0.6538 0.6397 3187855 PK04_103151 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H14 compound treatment 500376.0 -98200.0 -0.72 528529.0 -116000.0 -0.88 -1.1285 -0.995 3187856 PK04_103152 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H15 compound treatment 506206.0 -92400.0 -0.68 667177.0 23100.0 0.18 -0.3536 -0.5066 3070554 PK04_103153 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H16 compound treatment 550391.0 -48200.0 -0.35 650342.0 6260.0 0.05 -0.2155 -0.6062 3187857 PK04_103154 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H17 compound treatment 538113.0 -60500.0 -0.44 742376.0 98300.0 0.75 0.2153 0.2481 3187858 PK04_103155 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H18 compound treatment 580973.0 -17600.0 -0.13 712559.0 68500.0 0.52 0.2768 0.5165 3070555 PK04_103156 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H19 mock treatment 511887.0 -86700.0 -0.63 641205.0 -2880.0 -0.02 -0.4637 -0.731 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H20 mock treatment 537811.0 -60800.0 -0.44 690575.0 46500.0 0.35 -0.0645 -0.1136 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H21 compound treatment 552217.0 -46400.0 -0.34 600400.0 -43700.0 -0.33 -0.4744 -0.9999 3187859 PK04_103157 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H22 compound treatment 694046.0 95500.0 0.7 708378.0 64300.0 0.49 0.8391 0.9847 3070556 PK04_103158 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H23 compound treatment 585357.0 -13200.0 -0.1 574748.0 -69300.0 -0.53 -0.4408 -0.8231 3187860 PK04_103159 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 H24 compound treatment 566814.0 -31800.0 -0.23 622135.0 -21900.0 -0.17 -0.2821 -0.9868 3070597 PK04_103160 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I01 compound treatment 621977.0 23400.0 0.17 696148.0 52100.0 0.4 0.4007 0.9297 3187861 PK04_103161 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I02 compound treatment 619475.0 20900.0 0.15 569002.0 -75100.0 -0.57 -0.2952 -0.5 3187862 PK04_103162 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I03 compound treatment 463869.0 -135000.0 -0.99 604474.0 -39600.0 -0.3 -0.9094 -0.8828 3070598 PK04_103163 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I04 compound treatment 656361.0 57800.0 0.42 620956.0 -23100.0 -0.18 0.1746 0.3815 3187863 PK04_103164 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I05 mock treatment 639888.0 41300.0 0.3 588733.0 -55300.0 -0.42 -0.0837 -0.1616 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I06 mock treatment 533980.0 -64600.0 -0.47 634485.0 -9600.0 -0.07 -0.3856 -0.8067 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I07 compound treatment 554682.0 -43900.0 -0.32 739416.0 95300.0 0.72 0.2851 0.3599 3070599 PK04_103165 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I08 compound treatment 567203.0 -31400.0 -0.23 629769.0 -14300.0 -0.11 -0.2391 -0.9418 3187864 PK04_103166 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I09 compound treatment 492811.0 -106000.0 -0.77 732866.0 88800.0 0.67 -0.07 -0.0682 3187865 PK04_103167 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I10 compound treatment 646108.0 47500.0 0.35 674835.0 30800.0 0.23 0.411 0.9813 3070600 PK04_103168 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I11 compound treatment 636026.0 37400.0 0.27 664704.0 20600.0 0.16 0.3044 0.9649 3187866 PK04_103169 COCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I12 compound treatment 667395.0 68800.0 0.5 639844.0 -4240.0 -0.03 0.3331 0.6605 3187978 PK04_103170 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I13 compound treatment 610377.0 11800.0 0.09 654207.0 10100.0 0.08 0.1154 0.9984 3070601 PK04_103171 CCCCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I14 compound treatment 592968.0 -5610.0 -0.04 658172.0 14100.0 0.11 0.0467 0.4073 3187979 PK04_103172 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I15 compound treatment 625922.0 27300.0 0.2 617282.0 -26800.0 -0.2 -0.0026 -0.0089 3070602 PK04_103173 CC(C)C(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I16 compound treatment 466322.0 -132000.0 -0.97 572659.0 -71400.0 -0.54 -1.0676 -0.9627 3187980 PK04_103174 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I17 compound treatment 576763.0 -21800.0 -0.16 790902.0 147000.0 1.12 0.6759 0.5999 3070603 PK04_103175 COCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I18 compound treatment 570887.0 -27700.0 -0.2 588960.0 -55100.0 -0.42 -0.4393 -0.9444 3187981 PK04_103176 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I19 compound treatment 600105.0 1530.0 0.01 740969.0 96900.0 0.74 0.5284 0.7178 3070604 PK04_103177 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I20 compound treatment 596503.0 -2070.0 -0.02 612408.0 -31700.0 -0.24 -0.1809 -0.7502 3187982 PK04_103178 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I21 mock treatment 594233.0 -4340.0 -0.03 740859.0 96800.0 0.74 0.4974 0.6759 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I22 mock treatment 614608.0 16000.0 0.12 704982.0 60900.0 0.46 0.41 0.8591 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I23 compound treatment 476714.0 -122000.0 -0.89 608348.0 -35700.0 -0.27 -0.8221 -0.8825 3187983 PK04_103179 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 I24 compound treatment 559426.0 -39200.0 -0.29 540308.0 -104000.0 -0.79 -0.7599 -0.906 3070605 PK04_103180 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J01 compound treatment 630934.0 32400.0 0.24 559003.0 -85100.0 -0.65 -0.2897 -0.4209 3187984 PK04_103181 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J02 compound treatment 723818.0 125000.0 0.92 668815.0 24700.0 0.19 0.7805 0.8348 3187985 PK04_103182 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J03 compound treatment 542173.0 -56400.0 -0.41 663314.0 19200.0 0.15 -0.1884 -0.4304 3070606 PK04_103183 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J04 compound treatment 522057.0 -76500.0 -0.56 557690.0 -86400.0 -0.66 -0.8598 -0.9969 3187986 PK04_103184 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J05 mock treatment 587111.0 -11500.0 -0.08 623570.0 -20500.0 -0.16 -0.1695 -0.9578 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J06 mock treatment 519870.0 -78700.0 -0.58 717096.0 73000.0 0.55 -0.0148 -0.0185 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J07 compound treatment 565507.0 -33100.0 -0.24 629711.0 -14400.0 -0.11 -0.2482 -0.9354 3187987 PK04_103185 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J08 compound treatment 143980.0 -455000.0 -3.32 152363.0 -492000.0 -3.74 -4.9922 -0.9983 3070607 PK04_103186 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J09 compound treatment 563727.0 -34800.0 -0.25 696596.0 52500.0 0.4 0.1019 0.2152 3187988 PK04_103187 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J10 compound treatment 593076.0 -5500.0 -0.04 676447.0 32400.0 0.25 0.1454 0.5837 3070608 PK04_103188 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J11 compound treatment 617151.0 18600.0 0.14 714330.0 70200.0 0.53 0.4734 0.8597 3187989 PK04_103189 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J12 compound treatment 533709.0 -64900.0 -0.47 717874.0 73800.0 0.56 0.061 0.083 3070609 PK04_103190 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J13 compound treatment 368495.0 -230000.0 -1.68 367904.0 -276000.0 -2.1 -2.6733 -0.994 3187990 PK04_103191 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J14 compound treatment 620314.0 21700.0 0.16 614238.0 -29800.0 -0.23 -0.0479 -0.173 3187991 PK04_103192 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J15 compound treatment 690556.0 92000.0 0.67 625454.0 -18600.0 -0.14 0.3756 0.5464 3070610 PK04_103193 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J16 compound treatment 657702.0 59100.0 0.43 736217.0 92100.0 0.7 0.8007 0.9732 3187992 PK04_103194 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J17 compound treatment 310824.0 -288000.0 -2.1 330119.0 -314000.0 -2.39 -3.1745 -0.9981 3070654 PK04_103195 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J18 compound treatment 649702.0 51100.0 0.37 705133.0 61100.0 0.46 0.5923 0.9943 3187993 PK04_103196 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J19 compound treatment 500868.0 -97700.0 -0.71 660179.0 16100.0 0.12 -0.4188 -0.5777 3070655 PK04_103197 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J20 compound treatment 686927.0 88400.0 0.65 665417.0 21300.0 0.16 0.5715 0.8579 3187994 PK04_103198 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J21 mock treatment 607398.0 8820.0 0.06 625810.0 -18300.0 -0.14 -0.0525 -0.3432 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J22 mock treatment 588963.0 -9610.0 -0.07 571077.0 -73000.0 -0.55 -0.4419 -0.7904 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J23 compound treatment 482328.0 -116000.0 -0.85 594923.0 -49200.0 -0.37 -0.8652 -0.9318 3187995 PK04_103199 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 J24 compound treatment 637740.0 39200.0 0.29 720874.0 76800.0 0.58 0.615 0.9464 3070656 PK04_103200 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K01 compound treatment 632396.0 33800.0 0.25 632950.0 -11100.0 -0.08 0.1151 0.4403 3187996 PK04_103201 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K02 compound treatment 629893.0 31300.0 0.23 584268.0 -59800.0 -0.45 -0.1594 -0.3132 3187997 PK04_103202 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K03 compound treatment 591014.0 -7560.0 -0.06 653817.0 9740.0 0.07 0.0132 0.1428 3070657 PK04_103203 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K04 compound treatment 639276.0 40700.0 0.3 720591.0 76500.0 0.58 0.6215 0.9517 3187998 PK04_103204 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K05 compound treatment 568991.0 -29600.0 -0.22 663529.0 19400.0 0.15 -0.0485 -0.1852 3070658 PK04_103205 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K06 compound treatment 606067.0 7490.0 0.05 633486.0 -10600.0 -0.08 -0.0182 -0.1868 3187999 PK04_103206 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K07 mock treatment 672435.0 73900.0 0.54 660168.0 16100.0 0.12 0.4683 0.8457 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K08 mock treatment 594510.0 -4070.0 -0.03 625894.0 -18200.0 -0.14 -0.1187 -0.8401 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K09 compound treatment 639300.0 40700.0 0.3 623093.0 -21000.0 -0.16 0.0978 0.2896 3188000 PK04_103207 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K10 compound treatment 625711.0 27100.0 0.2 757084.0 113000.0 0.86 0.7473 0.8482 3070659 PK04_103208 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K11 compound treatment 678217.0 79600.0 0.58 663153.0 19100.0 0.14 0.5143 0.8569 3188108 PK04_103209 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K12 compound treatment 591932.0 -6640.0 -0.05 733690.0 89600.0 0.68 0.447 0.655 3188109 PK04_103210 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K13 compound treatment 635806.0 37200.0 0.27 653946.0 9860.0 0.07 0.2455 0.8694 3070660 PK04_103211 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K14 compound treatment 585489.0 -13100.0 -0.1 643692.0 -389.0 0.0 -0.0698 -0.7286 3188110 PK04_103212 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K15 mock treatment 660155.0 61600.0 0.45 729621.0 85500.0 0.65 0.7779 0.984 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K16 mock treatment 574017.0 -24600.0 -0.18 741011.0 96900.0 0.74 0.3937 0.5194 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K17 compound treatment 576972.0 -21600.0 -0.16 669341.0 25300.0 0.19 0.024 0.0964 3070661 PK04_103213 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K18 compound treatment 587761.0 -10800.0 -0.08 637274.0 -6810.0 -0.05 -0.0925 -0.9788 3188111 PK04_103214 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K19 compound treatment 554704.0 -43900.0 -0.32 649600.0 5520.0 0.04 -0.1972 -0.6095 3188112 PK04_103215 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K20 compound treatment 592209.0 -6370.0 -0.05 695226.0 51100.0 0.39 0.2418 0.6179 3070662 PK04_103216 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K21 compound treatment 503682.0 -94900.0 -0.69 618639.0 -25400.0 -0.19 -0.6274 -0.8709 3188113 PK04_103217 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K22 compound treatment 583046.0 -15500.0 -0.11 638170.0 -5910.0 -0.04 -0.1121 -0.9176 3188114 PK04_103218 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K23 mock treatment 489083.0 -109000.0 -0.8 617726.0 -26400.0 -0.2 -0.7078 -0.8575 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 K24 mock treatment 483960.0 -115000.0 -0.84 555597.0 -88500.0 -0.67 -1.068 -0.994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L01 compound treatment 701031.0 102000.0 0.75 766469.0 122000.0 0.93 1.1872 0.9943 3070663 PK04_103219 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L02 compound treatment 617538.0 19000.0 0.14 698846.0 54800.0 0.42 0.3922 0.8944 3188115 PK04_103220 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L03 compound treatment 559097.0 -39500.0 -0.29 549092.0 -95000.0 -0.72 -0.7144 -0.9192 3070664 PK04_103221 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L04 compound treatment 722996.0 124000.0 0.91 752401.0 108000.0 0.82 1.2253 0.9987 3188116 PK04_103222 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L05 compound treatment 587420.0 -11200.0 -0.08 628758.0 -15300.0 -0.12 -0.14 -0.9849 3070665 PK04_103223 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L06 compound treatment 579112.0 -19500.0 -0.14 598729.0 -45400.0 -0.34 -0.3443 -0.9235 3188117 PK04_103224 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L07 mock treatment 681108.0 82500.0 0.6 580191.0 -63900.0 -0.49 0.0836 0.1079 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L08 mock treatment 699954.0 101000.0 0.74 620602.0 -23500.0 -0.18 0.3981 0.5221 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L09 compound treatment 554556.0 -44000.0 -0.32 575030.0 -69100.0 -0.52 -0.5986 -0.9725 3188118 PK04_103225 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L10 compound treatment 659626.0 61000.0 0.45 750719.0 107000.0 0.81 0.8885 0.9606 3188119 PK04_103226 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L11 compound treatment 483436.0 -115000.0 -0.84 538935.0 -105000.0 -0.8 -1.1602 -0.9997 3070666 PK04_103227 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L12 compound treatment 659022.0 60400.0 0.44 672209.0 28100.0 0.21 0.4637 0.9444 3188120 PK04_103228 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L13 compound treatment 630133.0 31600.0 0.23 783008.0 139000.0 1.06 0.9095 0.8418 3188121 PK04_103229 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L14 compound treatment 423639.0 -175000.0 -1.28 568689.0 -75400.0 -0.57 -1.3096 -0.9343 3188122 PK04_103230 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L15 mock treatment 728921.0 130000.0 0.95 671491.0 27400.0 0.21 0.8213 0.8417 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L16 mock treatment 626460.0 27900.0 0.2 626653.0 -17400.0 -0.13 0.0506 0.208 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L17 compound treatment 536036.0 -62500.0 -0.46 602809.0 -41300.0 -0.31 -0.5451 -0.983 3070709 PK04_103231 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L18 compound treatment 633762.0 35200.0 0.26 792071.0 148000.0 1.12 0.9769 0.847 3188123 PK04_103232 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L19 compound treatment 699741.0 101000.0 0.74 560219.0 -83900.0 -0.64 0.0726 0.0744 3070710 PK04_103233 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L20 compound treatment 563437.0 -35100.0 -0.26 683718.0 39600.0 0.3 0.0312 0.0788 3188124 PK04_103234 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L21 compound treatment 598337.0 -240.0 0.0 647292.0 3210.0 0.02 0.016 0.6546 3070711 PK04_103235 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L22 compound treatment 562165.0 -36400.0 -0.27 677679.0 33600.0 0.26 -0.0078 -0.0212 3188125 PK04_103236 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L23 mock treatment 577702.0 -20900.0 -0.15 659169.0 15100.0 0.11 -0.0269 -0.1409 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 L24 mock treatment 619509.0 20900.0 0.15 621326.0 -22800.0 -0.17 -0.014 -0.0606 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M01 compound treatment 596102.0 -2470.0 -0.02 531843.0 -112000.0 -0.85 -0.6157 -0.722 3070712 PK04_103237 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M02 compound treatment 696795.0 98200.0 0.72 622218.0 -21900.0 -0.17 0.3905 0.5296 3188126 PK04_103238 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M03 compound treatment 640594.0 42000.0 0.31 670379.0 26300.0 0.2 0.3585 0.9783 3070713 PK04_103239 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M04 compound treatment 792232.0 194000.0 1.42 804643.0 161000.0 1.22 1.8639 0.9972 3188127 PK04_103240 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M05 compound treatment 626759.0 28200.0 0.21 643316.0 -765.0 -0.01 0.1416 0.6869 3188128 PK04_103241 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M06 compound treatment 611349.0 12800.0 0.09 691678.0 47600.0 0.36 0.3217 0.8615 3070714 PK04_103242 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M07 compound treatment 676567.0 78000.0 0.57 746933.0 103000.0 0.78 0.9558 0.988 3188237 PK04_103243 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M08 compound treatment 617436.0 18900.0 0.14 696127.0 52000.0 0.4 0.3771 0.9005 3070715 PK04_103244 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M09 mock treatment 700832.0 102000.0 0.75 779243.0 135000.0 1.03 1.2548 0.9879 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M10 mock treatment 676512.0 77900.0 0.57 753235.0 109000.0 0.83 0.9894 0.9833 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M11 compound treatment 583675.0 -14900.0 -0.11 677983.0 33900.0 0.26 0.1051 0.3756 3188238 PK04_103245 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M12 compound treatment 560472.0 -38100.0 -0.28 660263.0 16200.0 0.12 -0.1101 -0.3616 3188239 PK04_103246 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M13 mock treatment 765890.0 167000.0 1.22 835931.0 192000.0 1.46 1.8958 0.9962 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M14 mock treatment 632525.0 33900.0 0.25 719011.0 74900.0 0.57 0.5781 0.9308 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M15 compound treatment 629700.0 31100.0 0.23 725918.0 81800.0 0.62 0.6005 0.9071 3070716 PK04_103247 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M16 compound treatment 707408.0 109000.0 0.8 703540.0 59500.0 0.45 0.8822 0.964 3188240 PK04_103248 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M17 compound treatment 330744.0 -268000.0 -1.96 410755.0 -233000.0 -1.77 -2.6384 -0.9988 3070717 PK04_103249 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M18 compound treatment 649312.0 50700.0 0.37 688277.0 44200.0 0.34 0.4998 0.9988 3188241 PK04_103250 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M19 compound treatment 632290.0 33700.0 0.25 742052.0 98000.0 0.74 0.7006 0.8936 3188242 PK04_103251 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M20 compound treatment 635401.0 36800.0 0.27 713052.0 69000.0 0.52 0.5609 0.9521 3070718 PK04_103252 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M21 compound treatment 747390.0 149000.0 1.09 750931.0 107000.0 0.81 1.3435 0.9896 3188243 PK04_103253 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M22 compound treatment 714377.0 116000.0 0.85 670530.0 26400.0 0.2 0.7409 0.8512 3188244 PK04_103254 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M23 compound treatment 569512.0 -29100.0 -0.21 674415.0 30300.0 0.23 0.0126 0.0403 3188245 PK04_103255 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 M24 compound treatment 602444.0 3870.0 0.03 716441.0 72400.0 0.55 0.4087 0.7425 3070768 PK04_103256 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N01 compound treatment 645372.0 46800.0 0.34 568449.0 -75600.0 -0.57 -0.1643 -0.2457 3188246 PK04_103257 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N02 compound treatment 660572.0 62000.0 0.45 812600.0 169000.0 1.28 1.2258 0.9026 3188247 PK04_103258 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N03 compound treatment 612249.0 13700.0 0.1 793830.0 150000.0 1.14 0.8751 0.7663 3070772 PK04_103259 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N04 compound treatment 743554.0 145000.0 1.06 664934.0 20900.0 0.16 0.8617 0.8038 3188248 PK04_103260 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N05 compound treatment 705624.0 107000.0 0.78 723421.0 79300.0 0.6 0.9797 0.9917 3188249 PK04_103261 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N06 compound treatment 736583.0 138000.0 1.01 704090.0 60000.0 0.46 1.036 0.9355 3188250 PK04_103262 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N07 compound treatment 717217.0 119000.0 0.87 676092.0 32000.0 0.24 0.7855 0.8717 3070060 PK04_103263 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N08 compound treatment 776823.0 178000.0 1.3 808612.0 165000.0 1.25 1.8056 0.9998 3188251 PK04_103264 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N09 mock treatment 733860.0 135000.0 0.99 695554.0 51500.0 0.39 0.9761 0.9175 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N10 mock treatment 643185.0 44600.0 0.33 657103.0 13000.0 0.1 0.3006 0.8819 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N11 compound treatment 690838.0 92300.0 0.67 621512.0 -22600.0 -0.17 0.3559 0.5112 3070061 PK04_103265 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N12 compound treatment 758264.0 160000.0 1.17 729334.0 85300.0 0.65 1.2837 0.9613 3188252 PK04_103266 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N13 mock treatment 671650.0 73100.0 0.53 683790.0 39700.0 0.3 0.5912 0.9634 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N14 mock treatment 592090.0 -6490.0 -0.05 735867.0 91800.0 0.7 0.4595 0.6575 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N15 compound treatment 665173.0 66600.0 0.49 690745.0 46700.0 0.35 0.595 0.9878 3070062 PK04_103267 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N16 compound treatment 703017.0 104000.0 0.76 781196.0 137000.0 1.04 1.2766 0.9884 3188253 PK04_103268 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N17 compound treatment 472157.0 -126000.0 -0.92 597916.0 -46200.0 -0.35 -0.9017 -0.9119 3070063 PK04_103269 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N18 compound treatment 778418.0 180000.0 1.32 807011.0 163000.0 1.24 1.8052 0.9995 3188254 PK04_103270 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N19 compound treatment 663435.0 64900.0 0.47 729038.0 85000.0 0.65 0.7918 0.9885 3070064 PK04_103271 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N20 compound treatment 759578.0 161000.0 1.18 779076.0 135000.0 1.03 1.5577 0.9976 3188255 PK04_103272 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N21 compound treatment 658397.0 59800.0 0.44 656391.0 12300.0 0.09 0.3755 0.8393 3070065 PK04_103273 CCCCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N22 compound treatment 726054.0 127000.0 0.93 760785.0 117000.0 0.89 1.2861 0.9997 3188256 PK04_103274 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N23 compound treatment 622177.0 23600.0 0.17 755276.0 111000.0 0.84 0.7193 0.8343 3070066 PK04_103275 CC(C)C(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 N24 compound treatment 648972.0 50400.0 0.37 636492.0 -7590.0 -0.06 0.2198 0.5893 3188257 PK04_103276 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O01 compound treatment 727270.0 129000.0 0.94 762068.0 118000.0 0.9 1.2993 0.9997 3188258 PK04_103277 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O02 compound treatment 740285.0 142000.0 1.04 739755.0 95700.0 0.73 1.2467 0.9849 3070067 PK04_103278 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O03 compound treatment 760793.0 162000.0 1.19 624045.0 -20000.0 -0.15 0.7312 0.6114 3188259 PK04_103279 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O04 compound treatment 746946.0 148000.0 1.09 709381.0 65300.0 0.5 1.118 0.9371 3188369 PK04_103280 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O05 compound treatment 793146.0 195000.0 1.42 689873.0 45800.0 0.35 1.2521 0.8548 3070068 PK04_103281 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O06 compound treatment 650578.0 52000.0 0.38 680722.0 36600.0 0.28 0.4657 0.9882 3188370 PK04_103282 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O07 compound treatment 759326.0 161000.0 1.18 683500.0 39400.0 0.3 1.043 0.8598 3070069 PK04_103283 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O08 compound treatment 669313.0 70700.0 0.52 666546.0 22500.0 0.17 0.4865 0.893 3188371 PK04_103284 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O09 compound treatment 779840.0 181000.0 1.33 716794.0 72700.0 0.55 1.3279 0.9247 3188372 PK04_103285 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O10 compound treatment 728862.0 130000.0 0.95 656986.0 12900.0 0.1 0.743 0.7758 3070070 PK04_103286 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O11 mock treatment 796771.0 198000.0 1.45 642515.0 -1570.0 -0.01 1.0165 0.7013 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O12 mock treatment 753295.0 155000.0 1.13 638595.0 -5490.0 -0.04 0.7706 0.6806 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O13 compound treatment 761076.0 162000.0 1.19 633091.0 -11000.0 -0.08 0.7813 0.6558 3188373 PK04_103287 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O14 compound treatment 827418.0 229000.0 1.67 595044.0 -49000.0 -0.37 0.92 0.5366 3188374 PK04_103288 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O15 compound treatment 801802.0 203000.0 1.49 771569.0 127000.0 0.97 1.7357 0.9785 3070071 PK04_103289 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O16 compound treatment 688431.0 89900.0 0.66 734210.0 90100.0 0.68 0.9488 0.9998 3188375 PK04_103290 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O17 compound treatment 735221.0 137000.0 1.0 672825.0 28700.0 0.22 0.861 0.8418 3070072 PK04_103291 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O18 compound treatment 499012.0 -99600.0 -0.73 469452.0 -175000.0 -1.33 -1.4529 -0.9601 3188376 PK04_103292 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O19 compound treatment 691227.0 92700.0 0.68 719363.0 75300.0 0.57 0.8835 0.9964 3188377 PK04_103293 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O20 compound treatment 716482.0 118000.0 0.86 755914.0 112000.0 0.85 1.2104 1.0 3070073 PK04_103294 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O21 compound treatment 657546.0 59000.0 0.43 708597.0 64500.0 0.49 0.6515 0.998 3188378 PK04_103295 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O22 compound treatment 677652.0 79100.0 0.58 730323.0 86200.0 0.66 0.8722 0.9981 3188379 PK04_103296 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O23 compound treatment 625675.0 27100.0 0.2 702511.0 58400.0 0.44 0.454 0.9339 3070074 PK04_103297 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 O24 compound treatment 613409.0 14800.0 0.11 663933.0 19900.0 0.15 0.1833 0.9869 3188380 PK04_103298 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P01 compound treatment 722434.0 124000.0 0.91 670621.0 26500.0 0.2 0.783 0.8438 3070075 PK04_103299 COCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P02 compound treatment 739150.0 141000.0 1.03 815807.0 172000.0 1.3 1.6494 0.993 3188381 PK04_103300 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P03 compound treatment 857819.0 259000.0 1.9 795084.0 151000.0 1.15 2.1517 0.971 3188382 PK04_103301 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P04 compound treatment 695297.0 96700.0 0.71 724711.0 80600.0 0.61 0.9333 0.9974 3070118 PK04_103302 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P05 compound treatment 741963.0 143000.0 1.05 728656.0 84600.0 0.64 1.1958 0.9724 3188383 PK04_103303 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P06 compound treatment 714011.0 115000.0 0.84 822980.0 179000.0 1.36 1.5579 0.9738 3070119 PK04_103304 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P07 compound treatment 705580.0 107000.0 0.78 673653.0 29600.0 0.22 0.7122 0.8748 3188384 PK04_103305 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P08 compound treatment 767973.0 169000.0 1.24 732545.0 88500.0 0.67 1.3512 0.9587 3188385 PK04_103306 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P09 compound treatment 752695.0 154000.0 1.13 737863.0 93800.0 0.71 1.3007 0.9755 3070120 PK04_103307 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P10 compound treatment 643015.0 44400.0 0.32 615521.0 -28600.0 -0.22 0.0764 0.1955 3188386 PK04_103308 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P11 mock treatment 772800.0 174000.0 1.27 610386.0 -33700.0 -0.26 0.7199 0.554 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P12 mock treatment 708628.0 110000.0 0.8 718148.0 74100.0 0.56 0.967 0.9847 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P13 compound treatment 720103.0 122000.0 0.89 622390.0 -21700.0 -0.16 0.5119 0.5663 3070121 PK04_103309 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P14 compound treatment 733314.0 135000.0 0.99 699472.0 55400.0 0.42 0.9943 0.928 3188387 PK04_103310 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P15 compound treatment 731368.0 133000.0 0.97 778768.0 135000.0 1.02 1.4102 0.9997 3188388 PK04_103311 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P16 compound treatment 750116.0 152000.0 1.11 656468.0 12400.0 0.09 0.8502 0.7644 3070122 PK04_103312 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P17 compound treatment 690444.0 91900.0 0.67 652852.0 8770.0 0.07 0.5222 0.7734 3188389 PK04_103313 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P18 compound treatment 747165.0 149000.0 1.09 750108.0 106000.0 0.81 1.3379 0.9891 3188390 PK04_103314 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P19 compound treatment 618634.0 20100.0 0.15 652041.0 7960.0 0.06 0.1465 0.9232 3070123 PK04_103315 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P20 compound treatment 684962.0 86400.0 0.63 765946.0 122000.0 0.93 1.1013 0.9826 3188503 PK04_103316 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P21 compound treatment 667554.0 69000.0 0.5 788890.0 145000.0 1.1 1.1346 0.9375 3188504 PK04_103317 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P22 compound treatment 619683.0 21100.0 0.15 736743.0 92700.0 0.7 0.6069 0.8421 3070124 PK04_103318 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P23 compound treatment 674329.0 75800.0 0.55 692460.0 48400.0 0.37 0.6516 0.9801 3188505 PK04_103319 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2103 P24 compound treatment 612879.0 14300.0 0.1 698955.0 54900.0 0.42 0.3687 0.8579 3188506 PK04_103320 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A01 compound treatment 513840.0 -103000.0 -0.75 545149.0 -66700.0 -0.51 -0.8895 -0.9815 3220649 PK04_107001 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A02 compound treatment 578698.0 -37900.0 -0.28 640068.0 28300.0 0.21 -0.0442 -0.1261 3188507 PK04_107002 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A03 compound treatment 569901.0 -46700.0 -0.34 585675.0 -26100.0 -0.2 -0.3819 -0.9666 3220651 PK04_107003 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A04 compound treatment 683764.0 67200.0 0.49 568914.0 -42900.0 -0.33 0.1169 0.1983 3070126 PK04_107004 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A05 compound treatment 673283.0 56700.0 0.41 581879.0 -29900.0 -0.23 0.1323 0.2799 3220653 PK04_107005 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A06 compound treatment 700682.0 84100.0 0.61 575102.0 -36700.0 -0.28 0.2376 0.352 3070127 PK04_107006 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A07 compound treatment 637058.0 20400.0 0.15 605183.0 -6620.0 -0.05 0.0702 0.4449 3220655 PK04_107007 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A08 compound treatment 686051.0 69400.0 0.51 557443.0 -54400.0 -0.41 0.0671 0.1025 3070128 PK04_107008 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A09 compound treatment 643874.0 27300.0 0.2 540970.0 -70800.0 -0.54 -0.2395 -0.4174 3220657 PK04_107009 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A10 compound treatment 623551.0 6940.0 0.05 580766.0 -31000.0 -0.24 -0.1308 -0.5425 3070129 PK04_107010 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A11 compound treatment 625890.0 9280.0 0.07 598101.0 -13700.0 -0.1 -0.0256 -0.2061 3220659 PK04_107011 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A12 compound treatment 487052.0 -130000.0 -0.95 462082.0 -150000.0 -1.14 -1.4742 -0.9959 3188513 PK04_107012 CCCCCCc1nc(CCCc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)cc4CO[Si](C(C)C)(C(C)C)c41 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A13 mock treatment 588138.0 -28500.0 -0.21 649904.0 38100.0 0.29 0.0574 0.1611 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A14 mock treatment 747901.0 131000.0 0.96 584504.0 -27300.0 -0.21 0.5323 0.5419 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A15 compound treatment 664787.0 48200.0 0.35 509833.0 -102000.0 -0.77 -0.2986 -0.3509 3220661 PK04_107013 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A16 compound treatment 477176.0 -139000.0 -1.02 457699.0 -154000.0 -1.17 -1.5488 -0.9976 3188514 PK04_107014 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A17 compound treatment 662201.0 45600.0 0.33 625344.0 13500.0 0.1 0.3085 0.8842 3220663 PK04_107015 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3ccccc3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A18 compound treatment 583475.0 -33100.0 -0.24 589957.0 -21800.0 -0.17 -0.2887 -0.9829 3070178 PK04_107016 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A19 compound treatment 611875.0 -4740.0 -0.03 642644.0 30800.0 0.23 0.1412 0.5961 3220665 PK04_107017 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A20 compound treatment 578732.0 -37900.0 -0.28 648634.0 36800.0 0.28 0.002 0.005 3070179 PK04_107018 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A21 compound treatment 594075.0 -22500.0 -0.16 608616.0 -3190.0 -0.02 -0.1336 -0.8023 3220667 PK04_107019 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A22 compound treatment 632463.0 15900.0 0.12 531758.0 -80000.0 -0.61 -0.348 -0.5622 3070180 PK04_107020 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A23 compound treatment 585151.0 -31500.0 -0.23 623172.0 11400.0 0.09 -0.1016 -0.4134 3220669 PK04_107021 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 A24 compound treatment 573262.0 -43300.0 -0.32 524537.0 -87300.0 -0.66 -0.6929 -0.943 3070181 PK04_107022 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B01 compound treatment 747226.0 131000.0 0.96 605468.0 -6330.0 -0.05 0.6414 0.6706 3188518 PK04_107023 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B02 compound treatment 608765.0 -7850.0 -0.06 730612.0 119000.0 0.9 0.5976 0.6608 3188519 PK04_107024 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B03 compound treatment 625612.0 9000.0 0.07 493483.0 -118000.0 -0.9 -0.589 -0.6536 3070182 PK04_107025 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B04 compound treatment 653587.0 37000.0 0.27 710784.0 99000.0 0.75 0.7229 0.9047 3188520 PK04_107026 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B05 compound treatment 643037.0 26400.0 0.19 722241.0 110000.0 0.84 0.7299 0.8478 3188521 PK04_107027 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B06 compound treatment 645688.0 29100.0 0.21 573105.0 -38700.0 -0.29 -0.0575 -0.1585 3070183 PK04_107028 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B07 compound treatment 668652.0 52000.0 0.38 613599.0 1800.0 0.01 0.2788 0.732 3188640 PK04_107029 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B08 compound treatment 594806.0 -21800.0 -0.16 621272.0 9470.0 0.07 -0.0619 -0.3537 3188641 PK04_107030 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B09 compound treatment 687777.0 71200.0 0.52 715598.0 104000.0 0.79 0.9256 0.9797 3070184 PK04_107031 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B10 compound treatment 528795.0 -87800.0 -0.64 625218.0 13400.0 0.1 -0.382 -0.5875 3188642 PK04_107032 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B11 compound treatment 543587.0 -73000.0 -0.53 705917.0 94100.0 0.71 0.1279 0.1434 3070185 PK04_107033 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B12 compound treatment 633850.0 17200.0 0.13 636439.0 24600.0 0.19 0.2215 0.9815 3188643 PK04_107034 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B13 mock treatment 474478.0 -142000.0 -1.04 681586.0 69800.0 0.53 -0.3601 -0.3086 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B14 mock treatment 578842.0 -37800.0 -0.28 594113.0 -17700.0 -0.13 -0.2903 -0.9452 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B15 compound treatment 692072.0 75500.0 0.55 662515.0 50700.0 0.39 0.6626 0.9846 3188644 PK04_107035 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B16 compound treatment 646992.0 30400.0 0.22 584561.0 -27200.0 -0.21 0.0108 0.0355 3070186 PK04_107036 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B17 compound treatment 598329.0 -18300.0 -0.13 607451.0 -4350.0 -0.03 -0.1179 -0.8561 3188645 PK04_107037 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B18 compound treatment 599597.0 -17000.0 -0.12 699133.0 87300.0 0.66 0.3811 0.5646 3188646 PK04_107038 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B19 compound treatment 729043.0 112000.0 0.82 738206.0 126000.0 0.96 1.2604 0.997 3070187 PK04_107039 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B20 compound treatment 655268.0 38700.0 0.28 686438.0 74600.0 0.57 0.6008 0.9483 3188647 PK04_107040 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B21 compound treatment 622104.0 5490.0 0.04 648920.0 37100.0 0.28 0.2278 0.7998 3188648 PK04_107041 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B22 compound treatment 622934.0 6320.0 0.05 636976.0 25200.0 0.19 0.1679 0.8535 3070188 PK04_107042 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B23 compound treatment 640776.0 24200.0 0.18 717258.0 105000.0 0.8 0.6914 0.8428 3188649 PK04_107043 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 B24 compound treatment 663271.0 46700.0 0.34 657310.0 45500.0 0.35 0.4857 1.0 3188650 PK04_107044 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C01 compound treatment 490967.0 -126000.0 -0.92 542979.0 -68800.0 -0.52 -1.0194 -0.9643 3414054 PK04_107045 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C02 compound treatment 536789.0 -79800.0 -0.58 488078.0 -124000.0 -0.94 -1.0774 -0.9738 3188651 PK04_107046 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C03 compound treatment 507185.0 -109000.0 -0.8 548751.0 -63100.0 -0.48 -0.9045 -0.9699 3414055 PK04_107047 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C04 compound treatment 526908.0 -89700.0 -0.66 588276.0 -23500.0 -0.18 -0.5902 -0.8681 3070235 PK04_107048 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C05 compound treatment 533059.0 -83600.0 -0.61 596792.0 -15000.0 -0.11 -0.5127 -0.8248 3414056 PK04_107049 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C06 compound treatment 521438.0 -95200.0 -0.7 498678.0 -113000.0 -0.86 -1.0998 -0.9945 3070236 PK04_107050 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C07 compound treatment 497542.0 -119000.0 -0.87 603451.0 -8350.0 -0.06 -0.6606 -0.7566 3414057 PK04_107051 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C08 compound treatment 590172.0 -26400.0 -0.19 545715.0 -66100.0 -0.5 -0.4917 -0.914 3188655 PK04_107052 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C09 compound treatment 536819.0 -79800.0 -0.58 562061.0 -49700.0 -0.38 -0.6798 -0.9779 3220705 PK04_107053 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C10 compound treatment 620467.0 3860.0 0.03 588409.0 -23400.0 -0.18 -0.1057 -0.5876 3188656 PK04_107054 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C11 mock treatment 645569.0 29000.0 0.21 516067.0 -95700.0 -0.73 -0.3645 -0.4812 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C12 mock treatment 536693.0 -79900.0 -0.58 595066.0 -16700.0 -0.13 -0.5032 -0.8412 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C13 compound treatment 644717.0 28100.0 0.21 607437.0 -4360.0 -0.03 0.1219 0.5855 3220708 PK04_107055 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C14 compound treatment 574895.0 -41700.0 -0.31 620276.0 8470.0 0.06 -0.1702 -0.5459 3188772 PK04_107056 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C15 mock treatment 635952.0 19300.0 0.14 764472.0 153000.0 1.16 0.9201 0.7875 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C16 mock treatment 664426.0 47800.0 0.35 688912.0 77100.0 0.59 0.6615 0.9696 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C17 compound treatment 600996.0 -15600.0 -0.11 559410.0 -52400.0 -0.4 -0.3622 -0.8747 3220711 PK04_107057 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C18 compound treatment 505748.0 -111000.0 -0.81 581220.0 -30600.0 -0.23 -0.7376 -0.8745 3070242 PK04_107058 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C19 compound treatment 625672.0 9060.0 0.07 634575.0 22800.0 0.17 0.1692 0.9132 3220713 PK04_107059 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C20 compound treatment 518264.0 -98300.0 -0.72 626358.0 14600.0 0.11 -0.4304 -0.5914 3070245 PK04_107060 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C21 compound treatment 591162.0 -25400.0 -0.19 631679.0 19900.0 0.15 -0.0248 -0.1036 3220715 PK04_107061 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C22 compound treatment 547946.0 -68700.0 -0.5 621042.0 9240.0 0.07 -0.3054 -0.6024 3070527 PK04_107062 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C23 compound treatment 652178.0 35600.0 0.26 653253.0 41500.0 0.31 0.4066 0.9955 3220717 PK04_107063 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 C24 compound treatment 540083.0 -76500.0 -0.56 518196.0 -93600.0 -0.71 -0.8986 -0.993 3070530 PK04_107064 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D01 compound treatment 745420.0 129000.0 0.94 616680.0 4880.0 0.04 0.6923 0.7344 3188777 PK04_107065 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D02 compound treatment 614832.0 -1780.0 -0.01 579276.0 -32500.0 -0.25 -0.1839 -0.7433 3188778 PK04_107066 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D03 compound treatment 478691.0 -138000.0 -1.01 656634.0 44800.0 0.34 -0.4724 -0.4437 3070575 PK04_107067 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D04 compound treatment 578122.0 -38500.0 -0.28 525505.0 -86300.0 -0.66 -0.6626 -0.9287 3188779 PK04_107068 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D05 compound treatment 631284.0 14700.0 0.11 689435.0 77600.0 0.59 0.4929 0.8223 3188780 PK04_107069 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D06 compound treatment 595333.0 -21300.0 -0.16 526060.0 -85700.0 -0.65 -0.5706 -0.8521 3070579 PK04_107070 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D07 compound treatment 675114.0 58500.0 0.43 603219.0 -8580.0 -0.07 0.2564 0.5925 3188781 PK04_107071 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D08 compound treatment 725965.0 109000.0 0.8 612842.0 1040.0 0.01 0.5711 0.7141 3188782 PK04_107072 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D09 compound treatment 631738.0 15100.0 0.11 578094.0 -33700.0 -0.26 -0.1028 -0.3687 3188783 PK04_107073 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D10 compound treatment 561501.0 -55100.0 -0.4 568424.0 -43400.0 -0.33 -0.518 -0.995 3070632 PK04_107074 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D11 mock treatment 595035.0 -21600.0 -0.16 525458.0 -86300.0 -0.66 -0.5754 -0.8529 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D12 mock treatment 563898.0 -52700.0 -0.39 503992.0 -108000.0 -0.82 -0.8517 -0.9409 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D13 compound treatment 524535.0 -92100.0 -0.67 619146.0 7340.0 0.06 -0.4367 -0.6463 3188784 PK04_107075 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D14 compound treatment 656815.0 40200.0 0.29 728095.0 116000.0 0.88 0.8326 0.8942 3188785 PK04_107076 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D15 mock treatment 637151.0 20500.0 0.15 581428.0 -30400.0 -0.23 -0.0569 -0.2068 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D16 mock treatment 588963.0 -27600.0 -0.2 487831.0 -124000.0 -0.94 -0.8089 -0.8398 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D17 compound treatment 666123.0 49500.0 0.36 696348.0 84500.0 0.64 0.7102 0.9632 3070637 PK04_107077 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D18 compound treatment 588087.0 -28500.0 -0.21 627500.0 15700.0 0.12 -0.0632 -0.2629 3188786 PK04_107078 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D19 compound treatment 664044.0 47400.0 0.35 748158.0 136000.0 1.04 0.9778 0.895 3188787 PK04_107079 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D20 compound treatment 695683.0 79100.0 0.58 690684.0 78900.0 0.6 0.8326 0.9998 3070641 PK04_107080 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D21 compound treatment 753602.0 137000.0 1.0 721240.0 109000.0 0.83 1.2963 0.9957 3188905 PK04_107081 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D22 compound treatment 554825.0 -61800.0 -0.45 744080.0 132000.0 1.0 0.3911 0.3549 3188906 PK04_107082 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D23 compound treatment 703850.0 87200.0 0.64 767552.0 156000.0 1.18 1.2878 0.958 3070684 PK04_107083 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 D24 compound treatment 627978.0 11400.0 0.08 571290.0 -40500.0 -0.31 -0.1588 -0.4983 3188907 PK04_107084 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E01 mock treatment 580505.0 -36100.0 -0.26 607516.0 -4290.0 -0.03 -0.2097 -0.7883 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E02 mock treatment 546781.0 -69800.0 -0.51 574634.0 -37200.0 -0.28 -0.5608 -0.961 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E03 compound treatment 490602.0 -126000.0 -0.92 490120.0 -122000.0 -0.92 -1.3053 -1.0 3220739 PK04_107085 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E04 compound treatment 563958.0 -52700.0 -0.39 556887.0 -54900.0 -0.42 -0.5673 -0.9992 3070690 PK04_107086 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E05 compound treatment 526212.0 -90400.0 -0.66 566414.0 -45400.0 -0.34 -0.7113 -0.9539 3220741 PK04_107087 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E06 compound treatment 598714.0 -17900.0 -0.13 656398.0 44600.0 0.34 0.147 0.4048 3070694 PK04_107088 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E07 compound treatment 534487.0 -82100.0 -0.6 584509.0 -27300.0 -0.21 -0.5713 -0.8991 3220743 PK04_107089 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E08 compound treatment 537479.0 -79100.0 -0.58 524252.0 -87500.0 -0.67 -0.8795 -0.9976 3188910 PK04_107090 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E09 mock treatment 564138.0 -52500.0 -0.38 589164.0 -22600.0 -0.17 -0.3929 -0.9344 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E10 mock treatment 608080.0 -8530.0 -0.06 609054.0 -2750.0 -0.02 -0.0589 -0.8949 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E11 compound treatment 609540.0 -7070.0 -0.05 546520.0 -65300.0 -0.5 -0.3872 -0.7766 3188911 PK04_107091 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E12 compound treatment 655709.0 39100.0 0.29 627209.0 15400.0 0.12 0.2849 0.9223 3070742 PK04_107092 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E13 compound treatment 533611.0 -83000.0 -0.61 620531.0 8730.0 0.07 -0.3823 -0.6261 3188912 PK04_107093 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E14 compound treatment 576270.0 -40300.0 -0.3 700694.0 88900.0 0.68 0.2689 0.3649 3070746 PK04_107094 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E15 compound treatment 592398.0 -24200.0 -0.18 617415.0 5610.0 0.04 -0.0951 -0.5219 3188913 PK04_107095 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E16 compound treatment 707648.0 91000.0 0.67 644283.0 32500.0 0.25 0.6452 0.9088 3070750 PK04_107096 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E17 mock treatment 657857.0 41200.0 0.3 623314.0 11500.0 0.09 0.2751 0.8761 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E18 mock treatment 538303.0 -78300.0 -0.57 616190.0 4390.0 0.03 -0.3814 -0.6648 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E19 compound treatment 682416.0 65800.0 0.48 652719.0 40900.0 0.31 0.5601 0.9776 3220747 PK04_107097 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E20 compound treatment 577408.0 -39200.0 -0.29 736571.0 125000.0 0.95 0.4675 0.4721 3188915 PK04_107098 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E21 compound treatment 494335.0 -122000.0 -0.89 647788.0 36000.0 0.27 -0.439 -0.4695 3220749 PK04_107099 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E22 compound treatment 608280.0 -8330.0 -0.06 549653.0 -62100.0 -0.47 -0.3769 -0.7918 3070803 PK04_107100 CC(C)[Si](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)(C#Cc3ccc(Oc4ccccc4)cc3)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E23 compound treatment 637800.0 21200.0 0.15 543995.0 -67800.0 -0.52 -0.2547 -0.4734 3220751 PK04_107101 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 E24 compound treatment 647614.0 31000.0 0.23 593607.0 -18200.0 -0.14 0.0626 0.2357 3070808 PK04_107102 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F01 mock treatment 638562.0 22000.0 0.16 572116.0 -39700.0 -0.3 -0.0997 -0.2918 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F02 mock treatment 555720.0 -60900.0 -0.45 507662.0 -104000.0 -0.79 -0.8743 -0.963 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F03 compound treatment 748643.0 132000.0 0.97 598594.0 -13200.0 -0.1 0.6118 0.6302 3188918 PK04_107103 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F04 compound treatment 505905.0 -111000.0 -0.81 640240.0 28400.0 0.22 -0.4197 -0.5009 3188919 PK04_107104 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F05 compound treatment 636152.0 19500.0 0.14 662548.0 50700.0 0.39 0.3736 0.9088 3188920 PK04_107105 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F06 compound treatment 556492.0 -60100.0 -0.44 543577.0 -68200.0 -0.52 -0.6774 -0.9966 3188921 PK04_107106 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F07 compound treatment 563306.0 -53300.0 -0.39 574873.0 -36900.0 -0.28 -0.474 -0.987 3070852 PK04_107107 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F08 compound treatment 569704.0 -46900.0 -0.34 599854.0 -11900.0 -0.09 -0.3067 -0.8644 3188922 PK04_107108 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F09 mock treatment 561675.0 -54900.0 -0.4 557887.0 -53900.0 -0.41 -0.5737 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F10 mock treatment 689920.0 73300.0 0.54 637585.0 25800.0 0.2 0.5176 0.9068 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F11 compound treatment 569487.0 -47100.0 -0.34 676589.0 64800.0 0.49 0.1043 0.1736 3189029 PK04_107109 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F12 compound treatment 548018.0 -68600.0 -0.5 652890.0 41100.0 0.31 -0.134 -0.2268 3070859 PK04_107110 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F13 compound treatment 722455.0 106000.0 0.77 704125.0 92300.0 0.7 1.0433 0.9988 3189030 PK04_107111 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F14 compound treatment 573336.0 -43300.0 -0.32 679030.0 67200.0 0.51 0.1374 0.2286 3189031 PK04_107112 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F15 compound treatment 623370.0 6760.0 0.05 617020.0 5220.0 0.04 0.063 0.994 3070862 PK04_107113 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F16 compound treatment 630496.0 13900.0 0.1 581395.0 -30400.0 -0.23 -0.0915 -0.3628 3189032 PK04_107114 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F17 mock treatment 505564.0 -111000.0 -0.81 540594.0 -71200.0 -0.54 -0.9567 -0.9805 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F18 mock treatment 552950.0 -63700.0 -0.47 607569.0 -4230.0 -0.03 -0.3519 -0.7541 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F19 compound treatment 747640.0 131000.0 0.96 761874.0 150000.0 1.14 1.4837 0.9963 3189033 PK04_107115 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F20 compound treatment 670825.0 54200.0 0.4 682449.0 70600.0 0.54 0.6598 0.9889 3070022 PK04_107116 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F21 compound treatment 768836.0 152000.0 1.11 730569.0 119000.0 0.9 1.4252 0.9946 3189034 PK04_107117 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F22 compound treatment 659163.0 42600.0 0.31 725998.0 114000.0 0.87 0.8335 0.9043 3189035 PK04_107118 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F23 compound treatment 521065.0 -95500.0 -0.7 750050.0 138000.0 1.05 0.2486 0.197 3070031 PK04_107119 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 F24 compound treatment 636859.0 20200.0 0.15 579712.0 -32100.0 -0.24 -0.0677 -0.2373 3189036 PK04_107120 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G01 compound treatment 573336.0 -43300.0 -0.32 561138.0 -50700.0 -0.38 -0.4959 -0.9953 3220772 PK04_107121 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G02 compound treatment 537099.0 -79500.0 -0.58 576454.0 -35300.0 -0.27 -0.601 -0.9384 3070078 PK04_107122 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G03 mock treatment 567951.0 -48700.0 -0.36 535928.0 -75900.0 -0.58 -0.6592 -0.9731 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G04 mock treatment 504291.0 -112000.0 -0.82 553065.0 -58700.0 -0.45 -0.8963 -0.9589 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G05 compound treatment 580225.0 -36400.0 -0.27 588413.0 -23400.0 -0.18 -0.3138 -0.9807 3220775 PK04_107123 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G06 compound treatment 627714.0 11100.0 0.08 603316.0 -8490.0 -0.06 0.0118 0.1141 3070081 PK04_107124 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G07 compound treatment 568679.0 -47900.0 -0.35 625075.0 13300.0 0.1 -0.1766 -0.4841 3189039 PK04_107125 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G08 compound treatment 566295.0 -50300.0 -0.37 563859.0 -47900.0 -0.36 -0.5177 -1.0 3189040 PK04_107126 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G09 compound treatment 513391.0 -103000.0 -0.75 534696.0 -77100.0 -0.59 -0.948 -0.9921 3070086 PK04_107127 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G10 compound treatment 600998.0 -15600.0 -0.11 572459.0 -39300.0 -0.3 -0.2921 -0.9129 3189041 PK04_107128 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G11 compound treatment 577132.0 -39500.0 -0.29 583854.0 -27900.0 -0.21 -0.3543 -0.9886 3070089 PK04_107129 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G12 compound treatment 631545.0 14900.0 0.11 677145.0 65300.0 0.5 0.4282 0.8425 3189042 PK04_107130 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G13 compound treatment 699302.0 82700.0 0.6 551762.0 -60000.0 -0.46 0.1051 0.1387 3070134 PK04_107131 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G14 compound treatment 600931.0 -15700.0 -0.11 625151.0 13300.0 0.1 -0.0094 -0.0612 3070137 PK04_107132 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G15 compound treatment 625425.0 8810.0 0.06 607486.0 -4320.0 -0.03 0.0224 0.3097 3189043 PK04_107133 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G16 compound treatment 656334.0 39700.0 0.29 699098.0 87300.0 0.66 0.6743 0.9314 3189044 PK04_107134 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G17 compound treatment 636229.0 19600.0 0.14 581332.0 -30500.0 -0.23 -0.0622 -0.2285 3070143 PK04_107135 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G18 compound treatment 602102.0 -14500.0 -0.11 580292.0 -31500.0 -0.24 -0.2443 -0.933 3189045 PK04_107136 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G19 mock treatment 620521.0 3910.0 0.03 613967.0 2170.0 0.02 0.0319 0.9656 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G20 mock treatment 632671.0 16100.0 0.12 568631.0 -43200.0 -0.33 -0.1489 -0.4273 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G21 compound treatment 637486.0 20900.0 0.15 544019.0 -67800.0 -0.51 -0.2562 -0.477 3070191 PK04_107137 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G22 compound treatment 619976.0 3360.0 0.02 639357.0 27600.0 0.21 0.1654 0.7848 3189046 PK04_107138 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G23 compound treatment 619244.0 2630.0 0.02 629063.0 17300.0 0.13 0.1063 0.8023 3070196 PK04_107139 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 G24 compound treatment 602209.0 -14400.0 -0.11 574140.0 -37700.0 -0.29 -0.2768 -0.9079 3189047 PK04_107140 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H01 compound treatment 715880.0 99300.0 0.73 642805.0 31000.0 0.24 0.6799 0.8908 3189157 PK04_107141 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H02 compound treatment 552244.0 -64400.0 -0.47 689341.0 77500.0 0.59 0.0837 0.111 3189158 PK04_107142 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H03 mock treatment 590609.0 -26000.0 -0.19 509578.0 -102000.0 -0.78 -0.6836 -0.855 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H04 mock treatment 621215.0 4600.0 0.03 595853.0 -15900.0 -0.12 -0.0619 -0.492 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H05 compound treatment 535414.0 -81200.0 -0.59 574599.0 -37200.0 -0.28 -0.6197 -0.9424 3070201 PK04_107143 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H06 compound treatment 550777.0 -65800.0 -0.48 665988.0 54200.0 0.41 -0.0494 -0.0779 3189159 PK04_107144 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H07 compound treatment 647001.0 30400.0 0.22 690734.0 78900.0 0.6 0.5812 0.9088 3071172 PK04_107145 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H08 compound treatment 578080.0 -38500.0 -0.28 608603.0 -3200.0 -0.02 -0.2164 -0.7652 3071173 PK04_107146 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H09 compound treatment 618185.0 1570.0 0.01 719922.0 108000.0 0.82 0.5889 0.7169 3071174 PK04_107147 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H10 compound treatment 638361.0 21700.0 0.16 569688.0 -42100.0 -0.32 -0.1138 -0.3184 3189160 PK04_107148 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H11 compound treatment 650938.0 34300.0 0.25 674628.0 62800.0 0.48 0.515 0.955 3189161 PK04_107149 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H12 compound treatment 622387.0 5780.0 0.04 654829.0 43000.0 0.33 0.261 0.7919 3071175 PK04_107150 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H13 compound treatment 646172.0 29600.0 0.22 685913.0 74100.0 0.56 0.551 0.9136 3189162 PK04_107151 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H14 compound treatment 600054.0 -16600.0 -0.12 654462.0 42700.0 0.32 0.1435 0.4149 3189163 PK04_107152 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H15 compound treatment 643353.0 26700.0 0.2 644280.0 32500.0 0.25 0.3128 0.9934 3071176 PK04_107153 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H16 compound treatment 683011.0 66400.0 0.49 736816.0 125000.0 0.95 1.0149 0.9515 3189164 PK04_107154 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H17 compound treatment 656425.0 39800.0 0.29 634033.0 22200.0 0.17 0.3253 0.9664 3189165 PK04_107155 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H18 compound treatment 596109.0 -20500.0 -0.15 524804.0 -87000.0 -0.66 -0.5733 -0.846 3071177 PK04_107156 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H19 mock treatment 634401.0 17800.0 0.13 599666.0 -12100.0 -0.09 0.0268 0.1681 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H20 mock treatment 618854.0 2240.0 0.02 611746.0 -55.2 0.0 0.0113 0.6888 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H21 compound treatment 657054.0 40400.0 0.3 663332.0 51500.0 0.39 0.4859 0.9904 3189166 PK04_107157 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H22 compound treatment 641877.0 25300.0 0.18 632995.0 21200.0 0.16 0.2445 0.9976 3189167 PK04_107158 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H23 compound treatment 652140.0 35500.0 0.26 693491.0 81700.0 0.62 0.6225 0.9253 3071178 PK04_107159 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 H24 compound treatment 588392.0 -28200.0 -0.21 633331.0 21500.0 0.16 -0.0303 -0.115 3189168 PK04_107160 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I01 compound treatment 577046.0 -39600.0 -0.29 595151.0 -16700.0 -0.13 -0.294 -0.9311 3071179 PK04_107161 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I02 compound treatment 492279.0 -124000.0 -0.91 545472.0 -66300.0 -0.5 -0.9992 -0.9612 3189169 PK04_107162 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I03 compound treatment 581889.0 -34700.0 -0.25 621137.0 9340.0 0.07 -0.1294 -0.4908 3071180 PK04_107163 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I04 compound treatment 567210.0 -49400.0 -0.36 621742.0 9940.0 0.08 -0.2021 -0.5475 3189170 PK04_107164 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I05 mock treatment 586386.0 -30200.0 -0.22 546660.0 -65100.0 -0.49 -0.5062 -0.934 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I06 mock treatment 548119.0 -68500.0 -0.5 585084.0 -26700.0 -0.2 -0.4977 -0.9209 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I07 compound treatment 601266.0 -15300.0 -0.11 562959.0 -48800.0 -0.37 -0.3417 -0.8815 3071181 PK04_107165 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I08 compound treatment 630808.0 14200.0 0.1 635942.0 24100.0 0.18 0.2031 0.9637 3189171 PK04_107166 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I09 compound treatment 297663.0 -319000.0 -2.33 276771.0 -335000.0 -2.55 -3.449 -0.9991 3189172 PK04_107167 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I10 compound treatment 568118.0 -48500.0 -0.35 553079.0 -58700.0 -0.45 -0.5662 -0.9935 3071182 PK04_107168 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I11 compound treatment 594513.0 -22100.0 -0.16 600836.0 -11000.0 -0.08 -0.1732 -0.9525 3189173 PK04_107169 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I12 compound treatment 649130.0 32500.0 0.24 661160.0 49400.0 0.37 0.4333 0.9759 3189286 PK04_107170 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I13 compound treatment 556519.0 -60100.0 -0.44 584173.0 -27600.0 -0.21 -0.4592 -0.9428 3071183 PK04_107171 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I14 compound treatment 639780.0 23200.0 0.17 644722.0 32900.0 0.25 0.2967 0.982 3189287 PK04_107172 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I15 compound treatment 550437.0 -66200.0 -0.48 732346.0 121000.0 0.92 0.3053 0.2948 3071184 PK04_107173 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I16 compound treatment 750322.0 134000.0 0.98 718944.0 107000.0 0.81 1.267 0.9958 3189288 PK04_107174 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I17 compound treatment 676634.0 60000.0 0.44 546401.0 -65400.0 -0.5 -0.0409 -0.0617 3071185 PK04_107175 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I18 compound treatment 342158.0 -274000.0 -2.01 289161.0 -323000.0 -2.45 -3.1524 -0.9951 3189289 PK04_107176 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I19 compound treatment 572840.0 -43800.0 -0.32 646642.0 34800.0 0.26 -0.0392 -0.0944 3071186 PK04_107177 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I20 compound treatment 606498.0 -10100.0 -0.07 714312.0 103000.0 0.78 0.4984 0.6371 3189171 PK04_107178 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I21 mock treatment 663032.0 46400.0 0.34 622692.0 10900.0 0.08 0.2986 0.8544 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I22 mock treatment 587062.0 -29500.0 -0.22 657255.0 45500.0 0.35 0.0914 0.2243 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I23 compound treatment 515750.0 -101000.0 -0.74 545001.0 -66800.0 -0.51 -0.8804 -0.9833 3189290 PK04_107179 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 I24 compound treatment 558506.0 -58100.0 -0.42 544759.0 -67000.0 -0.51 -0.6606 -0.9959 3071182 PK04_107180 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J01 compound treatment 723728.0 107000.0 0.78 674710.0 62900.0 0.48 0.8918 0.9719 3189291 PK04_107181 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J02 compound treatment 655167.0 38600.0 0.28 691428.0 79600.0 0.6 0.6271 0.9396 3071187 PK04_107182 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J03 compound treatment 751442.0 135000.0 0.99 661861.0 50100.0 0.38 0.9661 0.9142 3189292 PK04_107183 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J04 compound treatment 608664.0 -7950.0 -0.06 711715.0 99900.0 0.76 0.4956 0.6511 3189293 PK04_107184 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J05 mock treatment 587052.0 -29600.0 -0.22 551931.0 -59900.0 -0.45 -0.4745 -0.9422 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J06 mock treatment 561420.0 -55200.0 -0.4 543346.0 -68500.0 -0.52 -0.6531 -0.9922 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J07 compound treatment 672322.0 55700.0 0.41 550431.0 -61400.0 -0.47 -0.0416 -0.0672 3071188 PK04_107185 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J08 compound treatment 674324.0 57700.0 0.42 657519.0 45700.0 0.35 0.544 0.9953 3189294 PK04_107186 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J09 compound treatment 696653.0 80000.0 0.59 669211.0 57400.0 0.44 0.7223 0.9895 3189295 PK04_107187 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J10 compound treatment 619185.0 2570.0 0.02 679348.0 67500.0 0.51 0.3762 0.7325 3071189 PK04_107188 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J11 compound treatment 750742.0 134000.0 0.98 582392.0 -29400.0 -0.22 0.5356 0.5324 3189296 PK04_107189 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J12 compound treatment 575554.0 -41100.0 -0.3 566048.0 -45800.0 -0.35 -0.4581 -0.9973 3189297 PK04_107190 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J13 compound treatment 668869.0 52300.0 0.38 670374.0 58600.0 0.44 0.5849 0.9971 3071190 PK04_107191 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J14 compound treatment 590653.0 -26000.0 -0.19 674075.0 62300.0 0.47 0.2003 0.3929 3189298 PK04_107192 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J15 compound treatment 836257.0 220000.0 1.61 758748.0 147000.0 1.12 1.9252 0.9842 3071191 PK04_107193 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J16 compound treatment 658893.0 42300.0 0.31 651413.0 39600.0 0.3 0.4314 0.9999 3189299 PK04_107194 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J17 compound treatment 720116.0 104000.0 0.76 654786.0 43000.0 0.33 0.7661 0.9294 3189300 PK04_107195 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J18 compound treatment 641692.0 25100.0 0.18 576367.0 -35400.0 -0.27 -0.0606 -0.1862 3071192 PK04_107196 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J19 compound treatment 690446.0 73800.0 0.54 743407.0 132000.0 1.0 1.0888 0.9582 3189301 PK04_107197 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J20 compound treatment 710607.0 94000.0 0.69 580080.0 -31700.0 -0.24 0.3157 0.4334 3189302 PK04_107198 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J21 mock treatment 565059.0 -51600.0 -0.38 668435.0 56600.0 0.43 0.0376 0.0658 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J22 mock treatment 758493.0 142000.0 1.04 517916.0 -93900.0 -0.71 0.2294 0.1822 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J23 compound treatment 656160.0 39500.0 0.29 761952.0 150000.0 1.14 1.0111 0.8592 3071251 PK04_107199 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 J24 compound treatment 633121.0 16500.0 0.12 669905.0 58100.0 0.44 0.3975 0.8686 3189414 PK04_107200 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K01 compound treatment 593564.0 -23000.0 -0.17 610473.0 -1330.0 -0.01 -0.1263 -0.7481 3071252 PK04_107201 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K02 compound treatment 450354.0 -166000.0 -1.22 657258.0 45500.0 0.35 -0.6156 -0.487 3189415 PK04_107202 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K03 compound treatment 582267.0 -34300.0 -0.25 669743.0 57900.0 0.44 0.1336 0.2637 3071253 PK04_107203 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K04 compound treatment 519111.0 -97500.0 -0.71 662831.0 51000.0 0.39 -0.2301 -0.2835 3189416 PK04_107204 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K05 compound treatment 574763.0 -41800.0 -0.31 582334.0 -29500.0 -0.22 -0.3747 -0.9882 3189417 PK04_107205 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K06 compound treatment 508595.0 -108000.0 -0.79 441991.0 -170000.0 -1.29 -1.4707 -0.9723 3071254 PK04_107206 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K07 mock treatment 677336.0 60700.0 0.44 616544.0 4740.0 0.04 0.3395 0.762 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K08 mock treatment 549607.0 -67000.0 -0.49 586754.0 -25000.0 -0.19 -0.481 -0.9151 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K09 compound treatment 719283.0 103000.0 0.75 611157.0 -644.0 0.0 0.5275 0.7025 3071255 PK04_107207 NC(=N)NCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K10 compound treatment 613875.0 -2740.0 -0.02 581795.0 -30000.0 -0.23 -0.1753 -0.7662 3189418 PK04_107208 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K11 compound treatment 613936.0 -2680.0 -0.02 627293.0 15500.0 0.12 0.0694 0.5816 3189419 PK04_107209 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K12 compound treatment 470131.0 -146000.0 -1.07 478156.0 -134000.0 -1.02 -1.4754 -0.9996 3071256 PK04_107210 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K13 compound treatment 571642.0 -45000.0 -0.33 597100.0 -14700.0 -0.11 -0.3115 -0.8969 3189420 PK04_107211 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K14 compound treatment 393082.0 -224000.0 -1.63 336940.0 -275000.0 -2.09 -2.6324 -0.9927 3071257 PK04_107212 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K15 mock treatment 700546.0 83900.0 0.61 646403.0 34600.0 0.26 0.6199 0.9284 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K16 mock treatment 658440.0 41800.0 0.31 567217.0 -44600.0 -0.34 -0.0232 -0.0508 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K17 compound treatment 704642.0 88000.0 0.64 588712.0 -23100.0 -0.18 0.3312 0.4964 1035256 PK04_107213 C#CCNCc1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K18 compound treatment 625176.0 8560.0 0.06 647230.0 35400.0 0.27 0.2346 0.849 3189421 PK04_107214 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K19 compound treatment 609869.0 -6740.0 -0.05 632906.0 21100.0 0.16 0.0785 0.468 3071258 PK04_107215 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K20 compound treatment 633119.0 16500.0 0.12 564643.0 -47200.0 -0.36 -0.168 -0.4443 3189422 PK04_107216 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K21 compound treatment 695278.0 78700.0 0.58 649881.0 38100.0 0.29 0.6114 0.9494 3189423 PK04_107217 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K22 compound treatment 398631.0 -218000.0 -1.59 424537.0 -187000.0 -1.42 -2.1331 -0.9984 3071259 PK04_107218 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K23 mock treatment 596928.0 -19700.0 -0.14 601274.0 -10500.0 -0.08 -0.1583 -0.9615 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 K24 mock treatment 638442.0 21800.0 0.16 577481.0 -34300.0 -0.26 -0.0715 -0.2338 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L01 compound treatment 715509.0 98900.0 0.72 700826.0 89000.0 0.68 0.9896 0.9994 3189424 PK04_107219 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L02 compound treatment 623472.0 6860.0 0.05 626263.0 14500.0 0.11 0.1132 0.9369 3189425 PK04_107220 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L03 compound treatment 718165.0 102000.0 0.74 695477.0 83700.0 0.64 0.9746 0.997 3071260 PK04_107221 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L04 compound treatment 563379.0 -53200.0 -0.39 717725.0 106000.0 0.8 0.2937 0.3286 3189426 PK04_107222 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L05 compound treatment 619973.0 3360.0 0.02 721559.0 110000.0 0.83 0.607 0.7276 3189427 PK04_107223 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L06 compound treatment 665557.0 48900.0 0.36 478795.0 -133000.0 -1.01 -0.4614 -0.4304 3071261 PK04_107224 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L07 mock treatment 714165.0 97600.0 0.71 601454.0 -10300.0 -0.08 0.4489 0.6254 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L08 mock treatment 549750.0 -66900.0 -0.49 592382.0 -19400.0 -0.15 -0.4501 -0.8812 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L09 compound treatment 642539.0 25900.0 0.19 565076.0 -46700.0 -0.35 -0.1169 -0.2905 3189428 PK04_107225 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L10 compound treatment 721112.0 105000.0 0.76 682134.0 70300.0 0.53 0.9182 0.9847 3189429 PK04_107226 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L11 compound treatment 609247.0 -7360.0 -0.05 639562.0 27800.0 0.21 0.111 0.5102 3071262 PK04_107227 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L12 compound treatment 614458.0 -2150.0 -0.02 609561.0 -2240.0 -0.02 -0.0232 -0.9993 3189430 PK04_107228 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L13 compound treatment 741199.0 125000.0 0.91 646916.0 35100.0 0.27 0.8329 0.8773 3189431 PK04_107229 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L14 compound treatment 705790.0 89200.0 0.65 663728.0 51900.0 0.39 0.7401 0.971 3071263 PK04_107230 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L15 mock treatment 814056.0 197000.0 1.44 646364.0 34600.0 0.26 1.2067 0.8222 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L16 mock treatment 667271.0 50700.0 0.37 576204.0 -35600.0 -0.27 0.0707 0.1542 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L17 compound treatment 691721.0 75100.0 0.55 591149.0 -20700.0 -0.16 0.2775 0.4857 3189432 PK04_107231 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L18 compound treatment 627600.0 11000.0 0.08 693055.0 81300.0 0.62 0.4933 0.7925 3189547 PK04_107232 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L19 compound treatment 630120.0 13500.0 0.1 719032.0 107000.0 0.81 0.6459 0.7871 3071264 PK04_107233 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L20 compound treatment 634634.0 18000.0 0.13 719844.0 108000.0 0.82 0.6736 0.8103 3189548 PK04_107234 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L21 compound treatment 804271.0 188000.0 1.37 644159.0 32400.0 0.25 1.1442 0.8207 3189549 PK04_107235 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L22 compound treatment 587521.0 -29100.0 -0.21 763343.0 152000.0 1.15 0.6636 0.5668 3071265 PK04_107236 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L23 mock treatment 699474.0 82900.0 0.61 730014.0 118000.0 0.9 1.0635 0.9817 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 L24 mock treatment 573896.0 -42700.0 -0.31 616411.0 4610.0 0.04 -0.1961 -0.6239 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M01 compound treatment 599965.0 -16600.0 -0.12 596349.0 -15500.0 -0.12 -0.1691 -0.9998 3189550 PK04_107237 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M02 compound treatment 508654.0 -108000.0 -0.79 527432.0 -84400.0 -0.64 -1.0115 -0.9946 3071266 PK04_107238 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M03 compound treatment 610332.0 -6280.0 -0.05 685709.0 73900.0 0.56 0.3645 0.6471 3189551 PK04_107239 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M04 compound treatment 711238.0 94600.0 0.69 656937.0 45100.0 0.34 0.7318 0.9475 3189552 PK04_107240 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M05 compound treatment 656904.0 40300.0 0.29 714378.0 103000.0 0.78 0.7594 0.9115 3071267 PK04_107241 CN(C)S(=O)(=O)NCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M06 compound treatment 698463.0 81900.0 0.6 705818.0 94000.0 0.71 0.9283 0.9961 3189553 PK04_107242 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M07 compound treatment 686186.0 69600.0 0.51 692061.0 80300.0 0.61 0.7909 0.996 3414058 PK04_107243 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M08 compound treatment 610625.0 -5990.0 -0.04 621688.0 9890.0 0.08 0.0222 0.2548 3189554 PK04_107244 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M09 mock treatment 559398.0 -57200.0 -0.42 619641.0 7840.0 0.06 -0.2537 -0.6004 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M10 mock treatment 524360.0 -92300.0 -0.67 714634.0 103000.0 0.78 0.0753 0.073 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M11 compound treatment 552477.0 -64100.0 -0.47 608253.0 -3550.0 -0.03 -0.3507 -0.7465 3189555 PK04_107245 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M12 compound treatment 536068.0 -80500.0 -0.59 596408.0 -15400.0 -0.12 -0.4992 -0.8313 3071269 PK04_107246 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M13 mock treatment 564222.0 -52400.0 -0.38 699734.0 87900.0 0.67 0.2014 0.2616 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M14 mock treatment 607265.0 -9350.0 -0.07 715594.0 104000.0 0.79 0.5092 0.6434 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M15 compound treatment 784129.0 168000.0 1.23 720536.0 109000.0 0.83 1.4504 0.9816 3189556 PK04_107247 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M16 compound treatment 681953.0 65300.0 0.48 680930.0 69100.0 0.53 0.7092 0.9989 3189557 PK04_107248 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M17 compound treatment 781587.0 165000.0 1.21 699231.0 87400.0 0.66 1.3228 0.9605 3189558 PK04_107249 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M18 compound treatment 658568.0 42000.0 0.31 577763.0 -34000.0 -0.26 0.0341 0.085 3071329 PK04_107250 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M19 compound treatment 627252.0 10600.0 0.08 682667.0 70900.0 0.54 0.4357 0.801 3189559 PK04_107251 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M20 compound treatment 772484.0 156000.0 1.14 756092.0 144000.0 1.1 1.5811 0.9998 3071330 PK04_107252 CCCC#C[Si](O[C@H](CC)c1cn(Cc2cccc(Cl)c2)nn1)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M21 compound treatment 732513.0 116000.0 0.85 677565.0 65800.0 0.5 0.9526 0.9682 3189560 PK04_107253 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M22 compound treatment 707734.0 91100.0 0.67 691703.0 79900.0 0.61 0.9004 0.9989 3071331 PK04_107254 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M23 compound treatment 677253.0 60600.0 0.44 622757.0 11000.0 0.08 0.3724 0.8254 3189561 PK04_107255 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 M24 compound treatment 549318.0 -67300.0 -0.49 617722.0 5920.0 0.04 -0.3162 -0.6398 3071332 PK04_107256 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N01 compound treatment 796275.0 180000.0 1.31 786184.0 174000.0 1.32 1.8658 1.0 3189562 PK04_107257 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N02 compound treatment 769779.0 153000.0 1.12 715142.0 103000.0 0.79 1.3472 0.9849 3189563 PK04_107258 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N03 compound treatment 887663.0 271000.0 1.98 746032.0 134000.0 1.02 2.1227 0.9523 3071333 PK04_107259 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N04 compound treatment 821580.0 205000.0 1.5 829989.0 218000.0 1.66 2.232 0.9987 3189564 PK04_107260 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N05 compound treatment 621809.0 5200.0 0.04 650826.0 39000.0 0.3 0.2365 0.7913 3189681 PK04_107261 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N06 compound treatment 671354.0 54700.0 0.4 669317.0 57500.0 0.44 0.592 0.999 3071334 PK04_107262 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N07 compound treatment 664951.0 48300.0 0.35 666546.0 54700.0 0.42 0.544 0.9967 3189682 PK04_107263 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N08 compound treatment 768576.0 152000.0 1.11 748969.0 137000.0 1.04 1.5227 0.9995 3071335 PK04_107264 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N09 mock treatment 640723.0 24100.0 0.18 710289.0 98500.0 0.75 0.6537 0.8505 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N10 mock treatment 741320.0 125000.0 0.91 689144.0 77300.0 0.59 1.0604 0.9774 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N11 compound treatment 812723.0 196000.0 1.43 779162.0 167000.0 1.27 1.9131 0.9982 3189683 PK04_107265 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N12 compound treatment 659375.0 42800.0 0.31 672531.0 60700.0 0.46 0.5474 0.9821 3189684 PK04_107266 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N13 mock treatment 709183.0 92600.0 0.68 739095.0 127000.0 0.97 1.1625 0.9848 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N14 mock treatment 630840.0 14200.0 0.1 664224.0 52400.0 0.4 0.3552 0.8629 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N15 compound treatment 843880.0 227000.0 1.66 700388.0 88600.0 0.67 1.6511 0.9208 3071336 PK04_107267 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N16 compound treatment 678920.0 62300.0 0.46 687808.0 76000.0 0.58 0.7305 0.9931 3189685 PK04_107268 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N17 compound treatment 670478.0 53900.0 0.39 742169.0 130000.0 0.99 0.9789 0.9184 3189686 PK04_107269 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N18 compound treatment 640676.0 24100.0 0.18 733524.0 122000.0 0.92 0.7783 0.8268 3071337 PK04_107270 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N19 compound treatment 854985.0 238000.0 1.74 733854.0 122000.0 0.93 1.8883 0.9563 3189687 PK04_107271 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N20 compound treatment 789236.0 173000.0 1.26 753729.0 142000.0 1.08 1.6551 0.9969 3189688 PK04_107272 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N21 compound treatment 784671.0 168000.0 1.23 670323.0 58500.0 0.44 1.1834 0.9055 3071339 PK04_107273 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N22 compound treatment 620953.0 4340.0 0.03 597057.0 -14700.0 -0.11 -0.0568 -0.4875 3189689 PK04_107274 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N23 compound treatment 858391.0 242000.0 1.77 666403.0 54600.0 0.41 1.5436 0.8499 3189690 PK04_107275 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 N24 compound treatment 704719.0 88100.0 0.64 708948.0 97100.0 0.74 0.9775 0.9977 3071341 PK04_107276 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O01 compound treatment 678176.0 61600.0 0.45 622703.0 10900.0 0.08 0.3769 0.8234 3414059 PK04_107277 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O02 compound treatment 596405.0 -20200.0 -0.15 555480.0 -56300.0 -0.43 -0.407 -0.8992 3189692 PK04_107278 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O03 compound treatment 662016.0 45400.0 0.33 609049.0 -2750.0 -0.02 0.22 0.6613 3414060 PK04_107279 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O04 compound treatment 709524.0 92900.0 0.68 664111.0 52300.0 0.4 0.7615 0.9674 3189693 PK04_107280 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O05 compound treatment 570433.0 -46200.0 -0.34 756230.0 144000.0 1.1 0.537 0.4678 3071393 PK04_107281 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O06 compound treatment 607083.0 -9530.0 -0.07 628740.0 16900.0 0.13 0.0417 0.2851 3189694 PK04_107282 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O07 compound treatment 713207.0 96600.0 0.71 665122.0 53300.0 0.41 0.7859 0.9652 3189695 PK04_107283 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O08 compound treatment 612806.0 -3810.0 -0.03 575766.0 -36000.0 -0.27 -0.2132 -0.775 3071395 PK04_107284 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O09 compound treatment 647806.0 31200.0 0.23 635114.0 23300.0 0.18 0.2865 0.9922 3189696 PK04_107285 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O10 compound treatment 676216.0 59600.0 0.44 537059.0 -74700.0 -0.57 -0.0933 -0.1303 3189697 PK04_107286 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O11 mock treatment 773034.0 156000.0 1.14 747629.0 136000.0 1.03 1.5385 0.9987 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O12 mock treatment 765432.0 149000.0 1.09 672303.0 60500.0 0.46 1.0946 0.9265 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O13 compound treatment 683112.0 66500.0 0.49 716883.0 105000.0 0.8 0.9084 0.9718 3071396 PK04_107287 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O14 compound treatment 543344.0 -73300.0 -0.54 565738.0 -46100.0 -0.35 -0.6263 -0.9787 3187592 PK04_107288 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O15 compound treatment 726587.0 110000.0 0.8 654943.0 43100.0 0.33 0.8004 0.9217 3187593 PK04_107289 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O16 compound treatment 706972.0 90400.0 0.66 631031.0 19200.0 0.15 0.5706 0.8431 3071397 PK04_107290 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O17 compound treatment 639823.0 23200.0 0.17 593844.0 -18000.0 -0.14 0.0236 0.1082 3187594 PK04_107291 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O18 compound treatment 757327.0 141000.0 1.03 586597.0 -25200.0 -0.19 0.5923 0.5658 3071398 PK04_107292 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O19 compound treatment 609371.0 -7240.0 -0.05 632627.0 20800.0 0.16 0.0744 0.4461 3187595 PK04_107293 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O20 compound treatment 738309.0 122000.0 0.89 558118.0 -53700.0 -0.41 0.3409 0.3483 3071399 PK04_107294 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O21 compound treatment 702021.0 85400.0 0.62 695868.0 84100.0 0.64 0.8933 0.9999 3187594 PK04_107295 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O22 compound treatment 722372.0 106000.0 0.77 717882.0 106000.0 0.81 1.1167 0.9998 3187596 PK04_107296 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O23 compound treatment 618282.0 1670.0 0.01 725507.0 114000.0 0.86 0.6194 0.717 3187597 PK04_107297 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 O24 compound treatment 662824.0 46200.0 0.34 644982.0 33200.0 0.25 0.4172 0.9896 3071400 PK04_107298 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P01 compound treatment 772524.0 156000.0 1.14 795897.0 184000.0 1.4 1.7952 0.9949 3187598 PK04_107299 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P02 compound treatment 750373.0 134000.0 0.98 670759.0 59000.0 0.45 1.0084 0.9373 3071401 PK04_107300 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P03 compound treatment 780951.0 164000.0 1.2 819861.0 208000.0 1.58 1.9675 0.9909 3187599 PK04_107301 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P04 compound treatment 834619.0 218000.0 1.59 694551.0 82700.0 0.63 1.5719 0.9172 3187600 PK04_107302 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P05 compound treatment 810654.0 194000.0 1.42 825640.0 214000.0 1.62 2.1521 0.9977 3071402 PK04_107303 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P06 compound treatment 748674.0 132000.0 0.97 677212.0 65400.0 0.5 1.0343 0.9523 3187601 PK04_107304 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P07 compound treatment 758895.0 142000.0 1.04 762536.0 151000.0 1.15 1.5455 0.9989 3187602 PK04_107305 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P08 compound treatment 754114.0 138000.0 1.01 769723.0 158000.0 1.2 1.5594 0.9961 3071403 PK04_107306 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P09 compound treatment 700848.0 84200.0 0.62 743139.0 131000.0 1.0 1.1411 0.9731 3187603 PK04_107307 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P10 compound treatment 679911.0 63300.0 0.46 753671.0 142000.0 1.08 1.0894 0.9288 3187604 PK04_107308 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P11 mock treatment 750213.0 134000.0 0.98 593174.0 -18600.0 -0.14 0.5908 0.5985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P12 mock treatment 650438.0 33800.0 0.25 732940.0 121000.0 0.92 0.8256 0.8664 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P13 compound treatment 706965.0 90400.0 0.66 797922.0 186000.0 1.41 1.467 0.94 3071404 PK04_107309 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P14 compound treatment 678615.0 62000.0 0.45 752387.0 141000.0 1.07 1.0758 0.9272 3187605 PK04_107310 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P15 compound treatment 764713.0 148000.0 1.08 884391.0 273000.0 2.07 2.2301 0.9543 3187606 PK04_107311 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P16 compound treatment 833204.0 217000.0 1.58 707294.0 95500.0 0.73 1.633 0.9373 3071405 PK04_107312 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P17 compound treatment 815798.0 199000.0 1.46 737448.0 126000.0 0.95 1.705 0.979 3187607 PK04_107313 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P18 compound treatment 732586.0 116000.0 0.85 835717.0 224000.0 1.7 1.8025 0.9483 3187608 PK04_107314 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P19 compound treatment 723171.0 107000.0 0.78 652454.0 40700.0 0.31 0.7694 0.9179 3187728 PK04_107315 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P20 compound treatment 815474.0 199000.0 1.45 676320.0 64500.0 0.49 1.3749 0.8959 3071452 PK04_107316 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P21 compound treatment 864577.0 248000.0 1.81 716891.0 105000.0 0.8 1.8468 0.9321 3187729 PK04_107317 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P22 compound treatment 762978.0 146000.0 1.07 810868.0 199000.0 1.51 1.8262 0.9857 3187730 PK04_107318 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P23 compound treatment 734066.0 117000.0 0.86 846827.0 235000.0 1.79 1.8699 0.9438 3071453 PK04_107319 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2107 P24 compound treatment 911031.0 294000.0 2.15 689584.0 77800.0 0.59 1.9403 0.869 3187731 PK04_107320 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A01 compound treatment 729837.0 129000.0 0.95 822724.0 182000.0 1.38 1.6466 0.9828 3187732 PK04_108001 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A02 compound treatment 607841.0 7340.0 0.05 662561.0 21900.0 0.17 0.1554 0.8902 3071454 PK04_108002 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A03 compound treatment 544653.0 -55800.0 -0.41 829528.0 189000.0 1.43 0.7256 0.4865 3187733 PK04_108003 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A04 compound treatment 579726.0 -20800.0 -0.15 597044.0 -43600.0 -0.33 -0.3419 -0.9374 3071455 PK04_108004 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A05 compound treatment 674511.0 74000.0 0.54 525559.0 -115000.0 -0.87 -0.2358 -0.2292 3187734 PK04_108005 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A06 compound treatment 475280.0 -125000.0 -0.92 492854.0 -148000.0 -1.12 -1.4417 -0.9949 3071456 PK04_108006 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A07 compound treatment 642129.0 41600.0 0.3 503613.0 -137000.0 -1.04 -0.5211 -0.4803 3187735 PK04_108007 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A08 compound treatment 574356.0 -26100.0 -0.19 649387.0 8690.0 0.07 -0.0885 -0.4375 3071457 PK04_108008 CC(=CCN[C@H](CO)c1ccccc1)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A09 compound treatment 572178.0 -28300.0 -0.21 563735.0 -77000.0 -0.58 -0.5599 -0.9027 3187736 PK04_108009 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A10 compound treatment 576255.0 -24200.0 -0.18 533730.0 -107000.0 -0.81 -0.7 -0.8416 3071458 PK04_108010 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A11 compound treatment 665449.0 64900.0 0.47 598664.0 -42000.0 -0.32 0.1101 0.1924 3071459 PK04_108011 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A12 compound treatment 147391.0 -453000.0 -3.31 179201.0 -461000.0 -3.51 -4.8221 -0.9996 3187737 PK04_108012 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A13 mock treatment 611701.0 11200.0 0.08 664510.0 23800.0 0.18 0.1859 0.9358 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A14 mock treatment 725183.0 125000.0 0.91 783909.0 143000.0 1.09 1.4141 0.9961 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A15 compound treatment 718593.0 118000.0 0.86 635283.0 -5410.0 -0.04 0.5816 0.6727 3187738 PK04_108013 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A16 compound treatment 603889.0 3390.0 0.02 599781.0 -40900.0 -0.31 -0.2023 -0.6487 3071460 PK04_108014 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A17 compound treatment 680137.0 79600.0 0.58 639185.0 -1510.0 -0.01 0.4037 0.6931 3187739 PK04_108015 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A18 compound treatment 654859.0 54400.0 0.4 601417.0 -39300.0 -0.3 0.0701 0.1411 3071461 PK04_108016 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A19 compound treatment 682401.0 81900.0 0.6 731970.0 91300.0 0.69 0.9138 0.9973 3187740 PK04_108017 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A20 compound treatment 580601.0 -19900.0 -0.15 474420.0 -166000.0 -1.26 -0.9961 -0.7834 3071462 PK04_108018 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A21 compound treatment 674985.0 74500.0 0.54 627486.0 -13200.0 -0.1 0.3142 0.5673 3187741 PK04_108019 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A22 compound treatment 572235.0 -28300.0 -0.21 577034.0 -63700.0 -0.48 -0.4881 -0.9281 3071463 PK04_108020 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A23 compound treatment 666650.0 66100.0 0.48 505900.0 -135000.0 -1.02 -0.382 -0.3373 3187742 PK04_108021 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 A24 compound treatment 702758.0 102000.0 0.75 536895.0 -104000.0 -0.79 -0.0288 -0.0265 3071464 PK04_108022 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B01 compound treatment 722380.0 122000.0 0.89 729682.0 89000.0 0.68 1.1083 0.9907 2133065 PK04_108023 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B02 compound treatment 508157.0 -92300.0 -0.68 574098.0 -66600.0 -0.51 -0.8353 -0.9899 3071465 PK04_108024 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B03 compound treatment 550337.0 -50200.0 -0.37 546652.0 -94000.0 -0.71 -0.7646 -0.952 2133224 PK04_108025 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B04 compound treatment 635938.0 35400.0 0.26 516479.0 -124000.0 -0.94 -0.484 -0.4946 1952196 PK04_108026 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B05 compound treatment 429604.0 -171000.0 -1.25 390462.0 -250000.0 -1.9 -2.2279 -0.9793 2133510 PK04_108027 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B06 compound treatment 354312.0 -246000.0 -1.8 421220.0 -219000.0 -1.67 -2.452 -0.9993 3071510 PK04_108028 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B07 compound treatment 616674.0 16200.0 0.12 495376.0 -145000.0 -1.1 -0.697 -0.6278 2128988 PK04_108029 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B08 compound treatment 618927.0 18400.0 0.13 482483.0 -158000.0 -1.2 -0.7546 -0.6239 3187870 PK04_108030 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B09 compound treatment 544856.0 -55600.0 -0.41 526370.0 -114000.0 -0.87 -0.9019 -0.9403 3187871 PK04_108031 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B10 compound treatment 690759.0 90300.0 0.66 672618.0 31900.0 0.24 0.6382 0.9076 3071511 PK04_108032 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B11 compound treatment 572811.0 -27700.0 -0.2 519645.0 -121000.0 -0.92 -0.7934 -0.8426 2129008 PK04_108033 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B12 compound treatment 726810.0 126000.0 0.92 598251.0 -42400.0 -0.32 0.4252 0.4346 3187872 PK04_108034 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B13 mock treatment 704848.0 104000.0 0.76 663112.0 22400.0 0.17 0.66 0.8442 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B14 mock treatment 687041.0 86500.0 0.63 557973.0 -82700.0 -0.63 0.0032 0.0035 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B15 compound treatment 627155.0 26700.0 0.19 671631.0 30900.0 0.24 0.304 0.9957 3187873 PK04_108035 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CCC\C=C\CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B16 compound treatment 610291.0 9790.0 0.07 583282.0 -57400.0 -0.44 -0.2578 -0.5832 3414061 PK04_108036 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B17 compound treatment 595586.0 -4920.0 -0.04 573784.0 -66900.0 -0.51 -0.3848 -0.7552 3187874 PK04_108037 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B18 compound treatment 679986.0 79500.0 0.58 629309.0 -11400.0 -0.09 0.3499 0.5954 3071513 PK04_108038 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B19 compound treatment 629562.0 29100.0 0.21 540089.0 -101000.0 -0.76 -0.3901 -0.4918 3187875 PK04_108039 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CCC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B20 compound treatment 603194.0 2690.0 0.02 545989.0 -94700.0 -0.72 -0.4948 -0.6875 3071514 PK04_108040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B21 compound treatment 693126.0 92600.0 0.68 636369.0 -4320.0 -0.03 0.4557 0.672 3187876 PK04_108041 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B22 compound treatment 617662.0 17200.0 0.13 596117.0 -44600.0 -0.34 -0.1507 -0.4173 3071515 PK04_108042 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B23 compound treatment 627824.0 27300.0 0.2 556920.0 -83800.0 -0.64 -0.3087 -0.4628 3187877 PK04_108043 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 B24 compound treatment 622221.0 21700.0 0.16 596545.0 -44100.0 -0.34 -0.1248 -0.3364 3071516 PK04_108044 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C01 compound treatment 602612.0 2110.0 0.02 707476.0 66800.0 0.51 0.3697 0.7283 3187878 PK04_108045 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C02 compound treatment 590623.0 -9880.0 -0.07 619043.0 -21600.0 -0.16 -0.1674 -0.9318 3071464 PK04_108046 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C03 compound treatment 559547.0 -41000.0 -0.3 614010.0 -26700.0 -0.2 -0.3551 -0.9819 3187879 PK04_108047 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C04 compound treatment 471225.0 -129000.0 -0.95 622921.0 -17800.0 -0.14 -0.764 -0.8 3071517 PK04_108048 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C05 compound treatment 544867.0 -55600.0 -0.41 615206.0 -25500.0 -0.19 -0.4246 -0.9423 3071518 PK04_108049 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C06 compound treatment 517418.0 -83100.0 -0.61 439109.0 -202000.0 -1.53 -1.5125 -0.918 3187880 PK04_108050 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C07 compound treatment 623599.0 23100.0 0.17 631836.0 -8860.0 -0.07 0.0719 0.3952 3187881 PK04_108051 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C08 compound treatment 134441.0 -466000.0 -3.41 148199.0 -492000.0 -3.74 -5.0556 -0.9989 3071519 PK04_108052 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C09 compound treatment 683184.0 82700.0 0.6 633822.0 -6870.0 -0.05 0.3907 0.6437 3187882 PK04_108053 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C10 compound treatment 415504.0 -185000.0 -1.35 490232.0 -150000.0 -1.14 -1.7649 -0.9965 3071520 PK04_108054 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C11 mock treatment 636699.0 36200.0 0.26 542004.0 -98700.0 -0.75 -0.3429 -0.4313 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C12 mock treatment 528984.0 -71500.0 -0.52 501442.0 -139000.0 -1.06 -1.1178 -0.9473 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C13 compound treatment 666571.0 66100.0 0.48 676742.0 36000.0 0.27 0.5353 0.9638 3187883 PK04_108055 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C14 compound treatment 528508.0 -72000.0 -0.53 584067.0 -56600.0 -0.43 -0.6765 -0.995 3071521 PK04_108056 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C15 mock treatment 654946.0 54400.0 0.4 597438.0 -43300.0 -0.33 0.0492 0.0953 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C16 mock treatment 654680.0 54200.0 0.4 618570.0 -22100.0 -0.17 0.1613 0.3748 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C17 compound treatment 613720.0 13200.0 0.1 607141.0 -33600.0 -0.25 -0.1119 -0.4104 3188001 PK04_108057 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C18 compound treatment 589440.0 -11100.0 -0.08 603837.0 -36900.0 -0.28 -0.2552 -0.8756 3071522 PK04_108058 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C19 compound treatment 698801.0 98300.0 0.72 637801.0 -2890.0 -0.02 0.4928 0.6852 3188002 PK04_108059 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C20 compound treatment 208148.0 -392000.0 -2.87 283860.0 -357000.0 -2.71 -3.9457 -0.9996 3071523 PK04_108060 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C21 compound treatment 696413.0 95900.0 0.7 681822.0 41100.0 0.31 0.7169 0.9337 3188003 PK04_108061 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C22 compound treatment 632974.0 32500.0 0.24 621870.0 -18800.0 -0.14 0.0668 0.241 3071524 PK04_108062 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C23 compound treatment 586322.0 -14200.0 -0.1 641982.0 1290.0 0.01 -0.0664 -0.6375 3188004 PK04_108063 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 C24 compound treatment 600014.0 -488.0 0.0 625321.0 -15400.0 -0.12 -0.0851 -0.7284 3071525 PK04_108064 CCOC(=O)C1OC[C@H](N1CC#C)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D01 compound treatment 568141.0 -32400.0 -0.24 681865.0 41200.0 0.31 0.0538 0.1372 3188005 PK04_108065 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D02 compound treatment 463024.0 -137000.0 -1.01 577039.0 -63700.0 -0.48 -1.0528 -0.9437 3414062 PK04_108066 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D03 compound treatment 495464.0 -105000.0 -0.77 599127.0 -41600.0 -0.32 -0.7664 -0.9228 3188006 PK04_108067 CC(C)C[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D04 compound treatment 450013.0 -150000.0 -1.1 457532.0 -183000.0 -1.39 -1.7621 -0.9933 3071527 PK04_108068 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D05 compound treatment 570807.0 -29700.0 -0.22 575375.0 -65300.0 -0.5 -0.5044 -0.9313 3188007 PK04_108069 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D06 compound treatment 417804.0 -183000.0 -1.34 549708.0 -91000.0 -0.69 -1.4335 -0.9529 3071528 PK04_108070 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D07 compound treatment 572832.0 -27700.0 -0.2 572085.0 -68600.0 -0.52 -0.5116 -0.9151 3188008 PK04_108071 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D08 compound treatment 516498.0 -84000.0 -0.61 623583.0 -17100.0 -0.13 -0.5263 -0.8382 3071529 PK04_108072 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D09 compound treatment 556581.0 -43900.0 -0.32 541079.0 -99600.0 -0.76 -0.7622 -0.9272 3188009 PK04_108073 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)CNC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D10 compound treatment 645720.0 45200.0 0.33 568431.0 -72300.0 -0.55 -0.1543 -0.2408 3071530 PK04_108074 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D11 mock treatment 555171.0 -45300.0 -0.33 581975.0 -58700.0 -0.45 -0.5498 -0.9893 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D12 mock treatment 586685.0 -13800.0 -0.1 559931.0 -80800.0 -0.61 -0.5053 -0.8126 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D13 compound treatment 578635.0 -21900.0 -0.16 574200.0 -66500.0 -0.51 -0.4703 -0.8875 3188010 PK04_108075 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D14 compound treatment 548273.0 -52200.0 -0.38 470948.0 -170000.0 -1.29 -1.1819 -0.8788 3071531 PK04_108076 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D15 mock treatment 631305.0 30800.0 0.23 525657.0 -115000.0 -0.87 -0.4587 -0.5082 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D16 mock treatment 622444.0 21900.0 0.16 565183.0 -75500.0 -0.57 -0.2922 -0.4905 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D17 compound treatment 684294.0 83800.0 0.61 638237.0 -2460.0 -0.02 0.4201 0.6853 3071578 PK04_108077 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D18 compound treatment 488176.0 -112000.0 -0.82 553969.0 -86700.0 -0.66 -1.0467 -0.994 3071579 PK04_108078 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D19 compound treatment 653262.0 52800.0 0.39 633572.0 -7120.0 -0.05 0.2346 0.6021 3071580 PK04_108079 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc6ccccc6)NC2=O)[C@@H]7O[C@]7(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D20 compound treatment 501503.0 -99000.0 -0.72 537213.0 -103000.0 -0.79 -1.0678 -0.9992 3188011 PK04_108080 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D21 compound treatment 682826.0 82300.0 0.6 572589.0 -68100.0 -0.52 0.0599 0.0754 3188012 PK04_108081 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D22 compound treatment 713136.0 113000.0 0.82 741997.0 101000.0 0.77 1.1266 0.9994 3071581 PK04_108082 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D23 compound treatment 633520.0 33000.0 0.24 670495.0 29800.0 0.23 0.3308 0.9995 3188013 PK04_108083 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 D24 compound treatment 654865.0 54400.0 0.4 617686.0 -23000.0 -0.17 0.1575 0.3627 3071582 PK04_108084 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E01 mock treatment 576847.0 -23700.0 -0.17 636406.0 -4290.0 -0.03 -0.1453 -0.8257 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E02 mock treatment 599819.0 -683.0 0.0 680573.0 39900.0 0.3 0.2107 0.6954 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E03 compound treatment 693420.0 92900.0 0.68 784615.0 144000.0 1.09 1.2536 0.9738 3188014 PK04_108085 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E04 compound treatment 333508.0 -267000.0 -1.95 374735.0 -266000.0 -2.02 -2.8093 -0.9999 3071583 PK04_108086 C/C=C/CN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E05 compound treatment 683556.0 83100.0 0.61 618788.0 -21900.0 -0.17 0.3118 0.4951 3188015 PK04_108087 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E06 compound treatment 554044.0 -46500.0 -0.34 569190.0 -71500.0 -0.54 -0.6243 -0.9745 3071584 PK04_108088 OCC(NCC#C)/C=C/c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E07 compound treatment 606770.0 6270.0 0.05 692527.0 51800.0 0.39 0.3109 0.7841 3188129 PK04_108089 CCOC(=O)C[C@H]1[C@H](OC(=O)c2cc3ccccc3oc2=O)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E08 compound treatment 465585.0 -135000.0 -0.99 591899.0 -48800.0 -0.37 -0.9598 -0.9106 3071585 PK04_108090 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E09 mock treatment 602763.0 2260.0 0.02 658098.0 17400.0 0.13 0.1052 0.7894 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E10 mock treatment 583619.0 -16900.0 -0.12 542201.0 -98500.0 -0.75 -0.6164 -0.8128 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E11 compound treatment 571034.0 -29500.0 -0.22 564770.0 -75900.0 -0.58 -0.5602 -0.9099 3071586 PK04_108091 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E12 compound treatment 599149.0 -1350.0 -0.01 578844.0 -61800.0 -0.47 -0.3392 -0.7218 3188130 PK04_108092 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E13 compound treatment 568642.0 -31900.0 -0.23 747670.0 107000.0 0.81 0.4099 0.4848 3188131 PK04_108093 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E14 compound treatment 556204.0 -44300.0 -0.32 657108.0 16400.0 0.12 -0.1409 -0.4059 3071587 PK04_108094 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E15 compound treatment 630179.0 29700.0 0.22 668953.0 28300.0 0.21 0.3053 1.0 3188132 PK04_108095 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E16 compound treatment 526575.0 -73900.0 -0.54 586273.0 -54400.0 -0.41 -0.6746 -0.9912 3071588 PK04_108096 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E17 mock treatment 632159.0 31700.0 0.23 617521.0 -23200.0 -0.18 0.0392 0.1349 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E18 mock treatment 514603.0 -85900.0 -0.63 629804.0 -10900.0 -0.08 -0.5027 -0.7934 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E19 compound treatment 578292.0 -22200.0 -0.16 599459.0 -41200.0 -0.31 -0.3363 -0.9532 3188133 PK04_108097 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E20 compound treatment 449726.0 -151000.0 -1.1 555574.0 -85100.0 -0.65 -1.2369 -0.9677 3071589 PK04_108098 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E21 compound treatment 619543.0 19000.0 0.14 657402.0 16700.0 0.13 0.1882 0.9989 3188134 PK04_108099 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E22 compound treatment 564752.0 -35700.0 -0.26 639244.0 -1450.0 -0.01 -0.1926 -0.7362 3071590 PK04_108100 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E23 compound treatment 566538.0 -34000.0 -0.25 618626.0 -22100.0 -0.17 -0.2942 -0.9817 3188135 PK04_108101 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 E24 compound treatment 504007.0 -96500.0 -0.71 533166.0 -108000.0 -0.82 -1.0766 -0.9973 3071591 PK04_108102 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F01 mock treatment 576615.0 -23900.0 -0.17 718176.0 77500.0 0.59 0.2927 0.4767 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F02 mock treatment 538450.0 -62100.0 -0.45 595206.0 -45500.0 -0.35 -0.5652 -0.991 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F03 compound treatment 559472.0 -41000.0 -0.3 488477.0 -152000.0 -1.16 -1.0298 -0.862 3188136 PK04_108103 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F04 compound treatment 515479.0 -85000.0 -0.62 653921.0 13200.0 0.1 -0.3686 -0.5852 3071592 PK04_108104 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F05 compound treatment 520286.0 -80200.0 -0.59 605015.0 -35700.0 -0.27 -0.6065 -0.9385 3188137 PK04_108105 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](Cc5ccccc5)NC(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F06 compound treatment 523826.0 -76700.0 -0.56 542044.0 -98600.0 -0.75 -0.9264 -0.9898 3071592 PK04_108106 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F07 compound treatment 515468.0 -85000.0 -0.62 608181.0 -32500.0 -0.25 -0.6144 -0.9182 3071593 PK04_108107 CC(C)[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F08 compound treatment 585938.0 -14600.0 -0.11 583513.0 -57200.0 -0.43 -0.3825 -0.8552 3188138 PK04_108108 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F09 mock treatment 550749.0 -49800.0 -0.36 555981.0 -84700.0 -0.64 -0.7123 -0.9636 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F10 mock treatment 560133.0 -40400.0 -0.3 646739.0 6050.0 0.05 -0.1763 -0.59 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F11 compound treatment 572889.0 -27600.0 -0.2 583953.0 -56700.0 -0.43 -0.4476 -0.9403 3188139 PK04_108109 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F12 compound treatment 499612.0 -101000.0 -0.74 515552.0 -125000.0 -0.95 -1.1939 -0.9921 3071594 PK04_108110 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F13 compound treatment 564536.0 -36000.0 -0.26 543810.0 -96900.0 -0.74 -0.7064 -0.9038 3188140 PK04_108111 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F14 compound treatment 610332.0 9830.0 0.07 541911.0 -98800.0 -0.75 -0.4798 -0.6365 3414064 PK04_108112 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F15 compound treatment 556903.0 -43600.0 -0.32 581655.0 -59000.0 -0.45 -0.5426 -0.986 3071596 PK04_108113 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@H](C)NC(=O)[C@@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F16 compound treatment 465183.0 -135000.0 -0.99 542176.0 -98500.0 -0.75 -1.229 -0.9905 3188141 PK04_108114 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F17 mock treatment 620237.0 19700.0 0.14 611629.0 -29100.0 -0.22 -0.0541 -0.205 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F18 mock treatment 657423.0 56900.0 0.42 576383.0 -64300.0 -0.49 -0.0511 -0.0796 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F19 compound treatment 592068.0 -8430.0 -0.06 674843.0 34200.0 0.26 0.1398 0.5244 3188142 PK04_108115 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F20 compound treatment 490766.0 -110000.0 -0.8 504428.0 -136000.0 -1.04 -1.2994 -0.9921 3071597 PK04_108116 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F21 compound treatment 671475.0 71000.0 0.52 668121.0 27400.0 0.21 0.5144 0.9196 3188143 PK04_108117 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@H](Cc5ccccc5)NC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F22 compound treatment 577657.0 -22800.0 -0.17 608542.0 -32200.0 -0.24 -0.2908 -0.9828 3071598 PK04_108118 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F23 compound treatment 621841.0 21300.0 0.16 658247.0 17600.0 0.13 0.2046 0.9969 3188144 PK04_108119 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC(=O)[C@@H](C)NC4=O)[C@@H]5O[C@@]51C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 F24 compound treatment 333954.0 -267000.0 -1.95 270203.0 -370000.0 -2.81 -3.3685 -0.9839 3188260 PK04_108120 CC(=O)O[C@@H]([C@@H]1CCCN1S(=O)(=O)c2ccccc2[N+](=O)[O-])C(=C)C3=CCN(C3)S(=O)(=O)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G01 compound treatment 552450.0 -48100.0 -0.35 653964.0 13300.0 0.1 -0.1772 -0.4847 3071599 PK04_108121 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G02 compound treatment 506472.0 -94000.0 -0.69 557789.0 -82900.0 -0.63 -0.9316 -0.999 3188261 PK04_108122 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G03 mock treatment 576858.0 -23600.0 -0.17 608099.0 -32600.0 -0.25 -0.2974 -0.9846 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G04 mock treatment 594892.0 -5610.0 -0.04 559946.0 -80700.0 -0.61 -0.4628 -0.7527 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G05 compound treatment 588954.0 -11500.0 -0.08 678693.0 38000.0 0.29 0.1444 0.4801 3188262 PK04_108123 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G06 compound treatment 492974.0 -108000.0 -0.79 522026.0 -119000.0 -0.9 -1.1935 -0.9977 3071600 PK04_108124 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G07 compound treatment 631665.0 31200.0 0.23 590240.0 -50500.0 -0.38 -0.1099 -0.2464 3189036 PK04_108125 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G08 compound treatment 551435.0 -49100.0 -0.36 544081.0 -96600.0 -0.73 -0.7727 -0.9458 3071601 PK04_108126 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G09 compound treatment 652763.0 52300.0 0.38 639940.0 -753.0 -0.01 0.2662 0.6965 3188263 PK04_108127 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G10 compound treatment 529217.0 -71300.0 -0.52 635943.0 -4750.0 -0.04 -0.3941 -0.7542 3071602 PK04_108128 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G11 compound treatment 593014.0 -7490.0 -0.05 699638.0 58900.0 0.45 0.2779 0.616 3188264 PK04_108129 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G12 compound treatment 506382.0 -94100.0 -0.69 608348.0 -32300.0 -0.25 -0.6605 -0.9037 3071603 PK04_108130 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G13 compound treatment 634096.0 33600.0 0.25 662434.0 21700.0 0.17 0.2905 0.9813 3188265 PK04_108131 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G14 compound treatment 548060.0 -52400.0 -0.38 591692.0 -49000.0 -0.37 -0.5344 -0.9999 3071604 PK04_108132 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G15 compound treatment 583692.0 -16800.0 -0.12 736976.0 96300.0 0.73 0.4303 0.5801 3188266 PK04_108133 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G16 compound treatment 535964.0 -64500.0 -0.47 631646.0 -9050.0 -0.07 -0.3823 -0.8016 3071651 PK04_108134 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G17 compound treatment 635972.0 35500.0 0.26 720471.0 79800.0 0.61 0.612 0.9283 3188267 PK04_108135 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G18 compound treatment 524821.0 -75700.0 -0.55 545675.0 -95000.0 -0.72 -0.9018 -0.9914 3071652 PK04_108136 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G19 mock treatment 612167.0 11700.0 0.09 599823.0 -40900.0 -0.31 -0.1592 -0.4945 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G20 mock treatment 620941.0 20400.0 0.15 732142.0 91400.0 0.69 0.5969 0.84 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G21 compound treatment 649197.0 48700.0 0.36 723060.0 82400.0 0.63 0.6943 0.9643 3189164 PK04_108137 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G22 compound treatment 513639.0 -86900.0 -0.64 564903.0 -75800.0 -0.58 -0.8563 -0.9988 3071653 PK04_108138 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G23 compound treatment 662562.0 62100.0 0.45 698821.0 58100.0 0.44 0.6332 0.9999 3189167 PK04_108139 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 G24 compound treatment 538907.0 -61600.0 -0.45 637230.0 -3460.0 -0.03 -0.3371 -0.7471 3188268 PK04_108140 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H01 compound treatment 583049.0 -17500.0 -0.13 651050.0 10400.0 0.08 -0.0346 -0.2309 3188269 PK04_108141 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H02 compound treatment 603073.0 2570.0 0.02 698435.0 57700.0 0.44 0.3235 0.7367 3071654 PK04_108142 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H03 mock treatment 491889.0 -109000.0 -0.79 655519.0 14800.0 0.11 -0.482 -0.6008 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H04 mock treatment 508781.0 -91700.0 -0.67 538001.0 -103000.0 -0.78 -1.0259 -0.9972 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H05 compound treatment 538123.0 -62400.0 -0.46 651915.0 11200.0 0.09 -0.2623 -0.5652 3188270 PK04_108143 CC(C)C[C@@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H06 compound treatment 531592.0 -68900.0 -0.5 763175.0 122000.0 0.93 0.3016 0.285 3071655 PK04_108144 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H07 compound treatment 553322.0 -47200.0 -0.35 518684.0 -122000.0 -0.93 -0.8994 -0.9094 3188271 PK04_108145 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H08 compound treatment 635779.0 35300.0 0.26 593559.0 -47100.0 -0.36 -0.0708 -0.1603 3071656 PK04_108146 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H09 compound treatment 591101.0 -9400.0 -0.07 593954.0 -46700.0 -0.36 -0.2997 -0.8286 3188272 PK04_108147 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H10 compound treatment 551048.0 -49500.0 -0.36 523617.0 -117000.0 -0.89 -0.8846 -0.9214 3071529 PK04_108148 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H11 compound treatment 521372.0 -79100.0 -0.58 523272.0 -117000.0 -0.89 -1.0399 -0.978 3188273 PK04_108149 CC(C)C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC1=O)[C@@H]6O[C@]6(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H12 compound treatment 555252.0 -45200.0 -0.33 600432.0 -40300.0 -0.31 -0.4503 -0.9992 3071527 PK04_108150 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H13 compound treatment 539663.0 -60800.0 -0.44 631694.0 -9000.0 -0.07 -0.3629 -0.8063 3071658 PK04_108151 CC(C)C[C@H]1NC(=O)[C@@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H14 compound treatment 536986.0 -63500.0 -0.46 528357.0 -112000.0 -0.85 -0.9319 -0.9591 3188274 PK04_108152 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H15 compound treatment 585549.0 -15000.0 -0.11 623401.0 -17300.0 -0.13 -0.1702 -0.9958 3188275 PK04_108153 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H16 compound treatment 684530.0 84000.0 0.61 583604.0 -57100.0 -0.43 0.1279 0.17 3071661 PK04_108154 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H17 compound treatment 539932.0 -60600.0 -0.44 644360.0 3670.0 0.03 -0.2935 -0.6613 3188391 PK04_108155 CC(C)C[C@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H18 compound treatment 527688.0 -72800.0 -0.53 570745.0 -69900.0 -0.53 -0.7523 -1.0 3071664 PK04_108156 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H19 mock treatment 510677.0 -89800.0 -0.66 587718.0 -53000.0 -0.4 -0.7491 -0.9723 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H20 mock treatment 529387.0 -71100.0 -0.52 588555.0 -52100.0 -0.4 -0.6478 -0.991 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H21 compound treatment 650050.0 49500.0 0.36 669204.0 28500.0 0.22 0.4094 0.9697 3188392 PK04_108157 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H22 compound treatment 586815.0 -13700.0 -0.1 625613.0 -15100.0 -0.11 -0.1518 -0.9977 3071666 PK04_108158 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H23 compound treatment 714670.0 114000.0 0.83 551270.0 -89400.0 -0.68 0.11 0.1022 3188393 PK04_108159 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H]6CCCN6C2=O)[C@@H]7O[C@]7(C)[C@H]4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 H24 compound treatment 633956.0 33500.0 0.24 601172.0 -39500.0 -0.3 -0.0393 -0.1015 3071711 PK04_108160 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I01 compound treatment 615567.0 15100.0 0.11 789512.0 149000.0 1.13 0.8773 0.7724 3188394 PK04_108161 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I02 compound treatment 549502.0 -51000.0 -0.37 611434.0 -29300.0 -0.22 -0.4209 -0.9694 3071714 PK04_108162 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I03 compound treatment 601806.0 1300.0 0.01 627431.0 -13300.0 -0.1 -0.0645 -0.6373 3188395 PK04_108163 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I04 compound treatment 510899.0 -89600.0 -0.66 591219.0 -49500.0 -0.38 -0.7291 -0.9652 3071715 PK04_108164 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I05 mock treatment 586378.0 -14100.0 -0.1 758768.0 118000.0 0.9 0.5612 0.6216 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I06 mock treatment 532284.0 -68200.0 -0.5 578181.0 -62500.0 -0.47 -0.6886 -0.9997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I07 compound treatment 687617.0 87100.0 0.64 619299.0 -21400.0 -0.16 0.3356 0.5104 3188396 PK04_108165 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I08 compound treatment 533801.0 -66700.0 -0.49 537640.0 -103000.0 -0.78 -0.8985 -0.9741 3071717 PK04_108166 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I09 compound treatment 621774.0 21300.0 0.16 728304.0 87600.0 0.67 0.5806 0.8495 3188397 PK04_108167 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I10 compound treatment 564006.0 -36500.0 -0.27 583975.0 -56700.0 -0.43 -0.4934 -0.9735 3071720 PK04_108168 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I11 compound treatment 617762.0 17300.0 0.13 661237.0 20500.0 0.16 0.1996 0.9945 3188398 PK04_108169 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I12 compound treatment 501682.0 -98800.0 -0.72 530819.0 -110000.0 -0.83 -1.1012 -0.9974 3071724 PK04_108170 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I13 compound treatment 548467.0 -52000.0 -0.38 726532.0 85800.0 0.65 0.192 0.2543 3071725 PK04_108171 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I14 compound treatment 579603.0 -20900.0 -0.15 601581.0 -39100.0 -0.3 -0.3182 -0.9522 3071727 PK04_108172 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I15 compound treatment 277170.0 -323000.0 -2.36 371970.0 -269000.0 -2.04 -3.1155 -0.9973 3188399 PK04_108173 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I16 compound treatment 548839.0 -51700.0 -0.38 611452.0 -29200.0 -0.22 -0.4242 -0.9679 3071766 PK04_108174 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I17 compound treatment 345316.0 -255000.0 -1.87 436694.0 -204000.0 -1.55 -2.4154 -0.9957 3188400 PK04_108175 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I18 compound treatment 535174.0 -65300.0 -0.48 697183.0 56500.0 0.43 -0.0344 -0.0535 3071767 PK04_108176 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I19 compound treatment 302009.0 -298000.0 -2.18 288354.0 -352000.0 -2.68 -3.4362 -0.9949 3188401 PK04_108177 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I20 compound treatment 579575.0 -20900.0 -0.15 645775.0 5080.0 0.04 -0.0809 -0.5127 3071770 PK04_108178 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I21 mock treatment 608165.0 7660.0 0.06 747894.0 107000.0 0.81 0.6155 0.754 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I22 mock treatment 588264.0 -12200.0 -0.09 642651.0 1960.0 0.01 -0.0528 -0.5816 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I23 compound treatment 450519.0 -150000.0 -1.1 600877.0 -39800.0 -0.3 -0.9895 -0.8696 3188402 PK04_108179 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 I24 compound treatment 517384.0 -83100.0 -0.61 584443.0 -56200.0 -0.43 -0.732 -0.9851 3071774 PK04_108180 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J01 compound treatment 604303.0 3800.0 0.03 719899.0 79200.0 0.6 0.4451 0.739 3188403 PK04_108181 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J02 compound treatment 499376.0 -101000.0 -0.74 658128.0 17400.0 0.13 -0.4293 -0.5714 3071776 PK04_108182 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J03 compound treatment 572791.0 -27700.0 -0.2 660119.0 19400.0 0.15 -0.0389 -0.1553 3188404 PK04_108183 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J04 compound treatment 522474.0 -78000.0 -0.57 676722.0 36000.0 0.27 -0.21 -0.3317 3188405 PK04_108184 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J05 mock treatment 559575.0 -40900.0 -0.3 607398.0 -33300.0 -0.25 -0.3905 -0.9965 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J06 mock treatment 540532.0 -60000.0 -0.44 636584.0 -4110.0 -0.03 -0.3322 -0.7555 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J07 compound treatment 539140.0 -61400.0 -0.45 689485.0 48800.0 0.37 -0.0552 -0.0949 3070928 PK04_108185 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)[C@H](C)NC4=O)[C@@H]6O[C@@]61C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J08 compound treatment 529906.0 -70600.0 -0.52 673904.0 33200.0 0.25 -0.1867 -0.3248 3070929 PK04_108186 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J09 compound treatment 522498.0 -78000.0 -0.57 565227.0 -75500.0 -0.57 -0.8088 -1.0 3070930 PK04_108187 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J10 compound treatment 509176.0 -91300.0 -0.67 516849.0 -124000.0 -0.94 -1.1375 -0.9859 3188406 PK04_108188 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J11 compound treatment 550155.0 -50300.0 -0.37 588705.0 -52000.0 -0.39 -0.5396 -0.9994 3188407 PK04_108189 CC(C)C[C@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C1=O)[C@@H]6O[C@]6(C)[C@H]3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J12 compound treatment 534324.0 -66200.0 -0.48 514643.0 -126000.0 -0.96 -1.0193 -0.95 3070931 PK04_108190 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J13 compound treatment 546689.0 -53800.0 -0.39 603233.0 -37500.0 -0.28 -0.4795 -0.9873 3070932 PK04_108191 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J14 compound treatment 547468.0 -53000.0 -0.39 570266.0 -70400.0 -0.54 -0.6526 -0.9875 3070933 PK04_108192 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J15 compound treatment 527474.0 -73000.0 -0.53 710618.0 69900.0 0.53 -0.002 -0.0027 3188522 PK04_108193 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J16 compound treatment 525804.0 -74700.0 -0.55 760633.0 120000.0 0.91 0.258 0.2429 3188523 PK04_108194 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J17 compound treatment 608746.0 8240.0 0.06 588321.0 -52400.0 -0.4 -0.2387 -0.5932 3070934 PK04_108195 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J18 compound treatment 635810.0 35300.0 0.26 544398.0 -96300.0 -0.73 -0.3347 -0.4314 3188524 PK04_108196 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J19 compound treatment 605160.0 4660.0 0.03 567062.0 -73600.0 -0.56 -0.3714 -0.6628 3070935 PK04_108197 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J20 compound treatment 638953.0 38500.0 0.28 715726.0 75000.0 0.57 0.6019 0.947 3188525 PK04_108198 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J21 mock treatment 673500.0 73000.0 0.53 625285.0 -15400.0 -0.12 0.2947 0.5393 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J22 mock treatment 588061.0 -12400.0 -0.09 733866.0 93200.0 0.71 0.4362 0.6112 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J23 compound treatment 648467.0 48000.0 0.35 632878.0 -7810.0 -0.06 0.2061 0.5792 3070936 PK04_108199 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 J24 compound treatment 605670.0 5170.0 0.04 583521.0 -57200.0 -0.43 -0.2804 -0.6431 3188526 PK04_108200 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K01 compound treatment 544593.0 -55900.0 -0.41 651612.0 10900.0 0.08 -0.2305 -0.5524 3070937 PK04_108201 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K02 compound treatment 598284.0 -2220.0 -0.02 612339.0 -28400.0 -0.22 -0.1638 -0.7582 3188527 PK04_108202 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K03 compound treatment 589775.0 -10700.0 -0.08 678129.0 37400.0 0.28 0.1456 0.4936 3188528 PK04_108203 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K04 compound treatment 388377.0 -212000.0 -1.55 509491.0 -131000.0 -1.0 -1.8017 -0.9771 3070938 PK04_108204 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K05 compound treatment 626782.0 26300.0 0.19 533944.0 -107000.0 -0.81 -0.4375 -0.525 3188529 PK04_108205 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K06 compound treatment 171119.0 -429000.0 -3.14 173454.0 -467000.0 -3.55 -4.7303 -0.9981 3070939 PK04_108206 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K07 mock treatment 585414.0 -15100.0 -0.11 743277.0 103000.0 0.78 0.473 0.601 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K08 mock treatment 619062.0 18600.0 0.14 646238.0 5550.0 0.04 0.1258 0.8849 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K09 compound treatment 508969.0 -91500.0 -0.67 471459.0 -169000.0 -1.29 -1.3824 -0.9537 3188530 PK04_108207 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K10 compound treatment 445086.0 -155000.0 -1.14 558510.0 -82200.0 -0.62 -1.2451 -0.9602 3188531 PK04_108208 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K11 compound treatment 534625.0 -65900.0 -0.48 601533.0 -39200.0 -0.3 -0.551 -0.9732 3070940 PK04_108209 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K12 compound treatment 429967.0 -171000.0 -1.25 466127.0 -175000.0 -1.33 -1.8196 -0.9995 3188532 PK04_108210 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K13 compound treatment 610623.0 10100.0 0.07 624158.0 -16500.0 -0.13 -0.0365 -0.2502 3188533 PK04_108211 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K14 compound treatment 551488.0 -49000.0 -0.36 558253.0 -82400.0 -0.63 -0.6963 -0.9649 3070941 PK04_108212 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K15 mock treatment 590461.0 -10000.0 -0.07 683737.0 43000.0 0.33 0.1793 0.535 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K16 mock treatment 611714.0 11200.0 0.08 620344.0 -20300.0 -0.15 -0.0513 -0.2933 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K17 compound treatment 571239.0 -29300.0 -0.21 714234.0 73500.0 0.56 0.2437 0.4074 3188534 PK04_108213 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K18 compound treatment 553851.0 -46700.0 -0.34 608371.0 -32300.0 -0.25 -0.4149 -0.987 3070942 PK04_108214 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K19 compound treatment 572909.0 -27600.0 -0.2 662935.0 22200.0 0.17 -0.0232 -0.0882 3188535 PK04_108215 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K20 compound treatment 547253.0 -53200.0 -0.39 604340.0 -36400.0 -0.28 -0.4706 -0.9858 3070943 PK04_108216 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K21 compound treatment 612764.0 12300.0 0.09 665322.0 24600.0 0.19 0.1957 0.9433 3188536 PK04_108217 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K22 compound treatment 559685.0 -40800.0 -0.3 558894.0 -81800.0 -0.62 -0.6505 -0.9436 3188537 PK04_108218 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K23 mock treatment 619771.0 19300.0 0.14 598461.0 -42200.0 -0.32 -0.1272 -0.363 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 K24 mock treatment 623541.0 23000.0 0.17 614484.0 -26200.0 -0.2 -0.0216 -0.083 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L01 compound treatment 605051.0 4550.0 0.03 495633.0 -145000.0 -1.1 -0.7557 -0.6854 3070944 PK04_108219 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L02 compound treatment 661804.0 61300.0 0.45 613846.0 -26800.0 -0.2 0.1728 0.3508 3188538 PK04_108220 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L03 compound treatment 626363.0 25900.0 0.19 604696.0 -36000.0 -0.27 -0.0596 -0.1794 3188539 PK04_108221 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L04 compound treatment 557222.0 -43300.0 -0.32 656957.0 16300.0 0.12 -0.1364 -0.4016 3215882 PK04_108222 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L05 compound treatment 526700.0 -73800.0 -0.54 536491.0 -104000.0 -0.79 -0.9414 -0.9826 3188540 PK04_108223 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L06 compound treatment 592036.0 -8470.0 -0.06 544470.0 -96200.0 -0.73 -0.5607 -0.7643 3215880 PK04_108224 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L07 mock treatment 555153.0 -45300.0 -0.33 766881.0 126000.0 0.96 0.4433 0.4371 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L08 mock treatment 606564.0 6060.0 0.04 561955.0 -78700.0 -0.6 -0.3916 -0.6529 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L09 compound treatment 613768.0 13300.0 0.1 558213.0 -82500.0 -0.63 -0.3745 -0.5906 3188541 PK04_108225 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L10 compound treatment 492539.0 -108000.0 -0.79 627285.0 -13400.0 -0.1 -0.6303 -0.7918 3188542 PK04_108226 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L11 compound treatment 167878.0 -433000.0 -3.16 154286.0 -486000.0 -3.7 -4.85 -0.997 3070947 PK04_108227 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L12 compound treatment 582453.0 -18000.0 -0.13 627425.0 -13300.0 -0.1 -0.1646 -0.9911 3188543 PK04_108228 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L13 compound treatment 264762.0 -336000.0 -2.46 411619.0 -229000.0 -1.74 -2.9667 -0.9858 3188544 PK04_108229 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L14 compound treatment 533020.0 -67500.0 -0.49 616606.0 -24100.0 -0.18 -0.4783 -0.9088 3070948 PK04_108230 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L15 mock treatment 597173.0 -3330.0 -0.02 655124.0 14400.0 0.11 0.0603 0.537 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L16 mock treatment 618010.0 17500.0 0.13 737366.0 96700.0 0.73 0.6098 0.818 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L17 compound treatment 640069.0 39600.0 0.29 593679.0 -47000.0 -0.36 -0.0479 -0.1043 3188657 PK04_108231 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L18 compound treatment 522822.0 -77700.0 -0.57 566761.0 -73900.0 -0.56 -0.7988 -1.0 3070949 PK04_108232 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L19 compound treatment 658262.0 57800.0 0.42 750607.0 110000.0 0.83 0.8891 0.9502 3188658 PK04_108233 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L20 compound treatment 576838.0 -23700.0 -0.17 646227.0 5530.0 0.04 -0.0926 -0.5202 3070950 PK04_108234 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L21 compound treatment 719100.0 119000.0 0.87 651472.0 10800.0 0.08 0.6712 0.7704 3188659 PK04_108235 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L22 compound treatment 651538.0 51000.0 0.37 624418.0 -16300.0 -0.12 0.1765 0.4489 3070951 PK04_108236 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L23 mock treatment 651992.0 51500.0 0.38 702148.0 61500.0 0.47 0.5964 0.9943 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 L24 mock treatment 567377.0 -33100.0 -0.24 652655.0 12000.0 0.09 -0.107 -0.4137 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M01 compound treatment 610549.0 10000.0 0.07 634923.0 -5770.0 -0.04 0.021 0.245 3188660 PK04_108237 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M02 compound treatment 592780.0 -7720.0 -0.06 578260.0 -62400.0 -0.47 -0.3753 -0.7857 3070952 PK04_108238 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M03 compound treatment 544225.0 -56300.0 -0.41 681683.0 41000.0 0.31 -0.0708 -0.1372 3188661 PK04_108239 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M04 compound treatment 373718.0 -227000.0 -1.66 556142.0 -84600.0 -0.64 -1.6269 -0.9148 3070953 PK04_108240 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M05 compound treatment 639959.0 39500.0 0.29 777982.0 137000.0 1.04 0.9415 0.8701 3188662 PK04_108241 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M06 compound treatment 586069.0 -14400.0 -0.11 621329.0 -19400.0 -0.15 -0.1787 -0.9867 3070954 PK04_108242 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M07 compound treatment 603635.0 3130.0 0.02 719298.0 78600.0 0.6 0.4384 0.7337 3188663 PK04_108243 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M08 compound treatment 148526.0 -452000.0 -3.31 161083.0 -480000.0 -3.64 -4.9136 -0.9988 3188664 PK04_108244 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M09 mock treatment 601611.0 1110.0 0.01 567950.0 -72700.0 -0.55 -0.385 -0.6967 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M10 mock treatment 566998.0 -33500.0 -0.25 764089.0 123000.0 0.94 0.4896 0.5053 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M11 compound treatment 617968.0 17500.0 0.13 679494.0 38800.0 0.29 0.2988 0.93 3070955 PK04_108245 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M12 compound treatment 510060.0 -90400.0 -0.66 566288.0 -74400.0 -0.57 -0.8674 -0.9969 3188665 PK04_108246 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M13 mock treatment 631617.0 31100.0 0.23 637195.0 -3500.0 -0.03 0.1421 0.6203 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M14 mock treatment 613225.0 12700.0 0.09 842599.0 202000.0 1.53 1.1504 0.7486 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M15 compound treatment 641120.0 40600.0 0.3 766910.0 126000.0 0.96 0.888 0.8847 3188666 PK04_108247 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M16 compound treatment 515948.0 -84600.0 -0.62 591717.0 -49000.0 -0.37 -0.7003 -0.9704 3070994 PK04_108248 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M17 compound treatment 534378.0 -66100.0 -0.48 656320.0 15600.0 0.12 -0.258 -0.5181 3188667 PK04_108249 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M18 compound treatment 623638.0 23100.0 0.17 679143.0 38500.0 0.29 0.3262 0.9663 3070995 PK04_108250 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M19 compound treatment 614887.0 14400.0 0.11 603824.0 -36900.0 -0.28 -0.1237 -0.4133 3188668 PK04_108251 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M20 compound treatment 562593.0 -37900.0 -0.28 783049.0 142000.0 1.08 0.5687 0.5094 2133134 PK04_108252 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M21 compound treatment 436973.0 -164000.0 -1.2 511109.0 -130000.0 -0.98 -1.5417 -0.9953 3070996 PK04_108253 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M22 compound treatment 623263.0 22800.0 0.17 677406.0 36700.0 0.28 0.3149 0.9696 2133147 PK04_108254 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M23 compound treatment 665781.0 65300.0 0.48 695501.0 54800.0 0.42 0.632 0.9977 3070997 PK04_108255 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 M24 compound treatment 566304.0 -34200.0 -0.25 686759.0 46100.0 0.35 0.0706 0.1642 3188671 PK04_108256 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N01 compound treatment 820761.0 220000.0 1.61 728190.0 87500.0 0.66 1.609 0.9234 3188672 PK04_108257 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N02 compound treatment 529868.0 -70600.0 -0.52 643211.0 2520.0 0.02 -0.3517 -0.6805 3070998 PK04_108258 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N03 compound treatment 607802.0 7300.0 0.05 758372.0 118000.0 0.89 0.6699 0.748 3188673 PK04_108259 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N04 compound treatment 606738.0 6240.0 0.05 817889.0 177000.0 1.35 0.9841 0.7306 3070999 PK04_108260 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N05 compound treatment 591930.0 -8570.0 -0.06 762833.0 122000.0 0.93 0.6118 0.6578 3188674 PK04_108261 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N06 compound treatment 436085.0 -164000.0 -1.2 553516.0 -87200.0 -0.66 -1.3185 -0.9605 3071000 PK04_108262 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N07 compound treatment 649153.0 48700.0 0.36 653233.0 12500.0 0.1 0.3189 0.8659 3188675 PK04_108263 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N08 compound treatment 613955.0 13500.0 0.1 616714.0 -24000.0 -0.18 -0.0592 -0.2861 3188676 PK04_108264 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N09 mock treatment 644848.0 44300.0 0.32 735764.0 95100.0 0.72 0.74 0.9347 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N10 mock treatment 572268.0 -28200.0 -0.21 777026.0 136000.0 1.04 0.5863 0.5552 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N11 compound treatment 584311.0 -16200.0 -0.12 776833.0 136000.0 1.03 0.6476 0.6221 3071001 PK04_108265 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N12 compound treatment 729276.0 129000.0 0.94 768146.0 127000.0 0.97 1.3506 0.9999 3188677 PK04_108266 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N13 mock treatment 646325.0 45800.0 0.34 663554.0 22900.0 0.17 0.3598 0.9532 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N14 mock treatment 592681.0 -7820.0 -0.06 620877.0 -19800.0 -0.15 -0.1469 -0.9121 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N15 compound treatment 625955.0 25500.0 0.19 612135.0 -28600.0 -0.22 -0.0218 -0.0762 3071002 PK04_108267 OCC1CC(=NO1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N16 compound treatment 712272.0 112000.0 0.82 703086.0 62400.0 0.47 0.9131 0.9664 3188788 PK04_108268 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N17 compound treatment 586095.0 -14400.0 -0.11 591358.0 -49300.0 -0.37 -0.3395 -0.8721 3071004 PK04_108269 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N18 compound treatment 587159.0 -13300.0 -0.1 565482.0 -75200.0 -0.57 -0.473 -0.8161 3071005 PK04_108270 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N19 compound treatment 775748.0 175000.0 1.28 768191.0 127000.0 0.97 1.5911 0.9905 3414065 PK04_108271 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N20 compound treatment 636705.0 36200.0 0.26 734764.0 94100.0 0.71 0.6925 0.9087 3188790 PK04_108272 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N21 compound treatment 592586.0 -7920.0 -0.06 735713.0 95000.0 0.72 0.4695 0.6483 3071008 PK04_108273 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N22 compound treatment 683581.0 83100.0 0.61 736291.0 95600.0 0.73 0.9431 0.9961 3188791 PK04_108274 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N23 compound treatment 748631.0 148000.0 1.08 715366.0 74700.0 0.57 1.1671 0.9544 3188792 PK04_108275 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 N24 compound treatment 567277.0 -33200.0 -0.24 720559.0 79900.0 0.61 0.2572 0.3935 3188793 PK04_108276 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O01 compound treatment 541859.0 -58600.0 -0.43 564485.0 -76200.0 -0.58 -0.7126 -0.9891 3071055 PK04_108277 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O02 compound treatment 632813.0 32300.0 0.24 685385.0 44700.0 0.34 0.4072 0.9843 2129060 PK04_108278 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O03 compound treatment 343235.0 -257000.0 -1.88 629544.0 -11100.0 -0.08 -1.3903 -0.7382 3188794 PK04_108279 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O04 compound treatment 593215.0 -7290.0 -0.05 777937.0 137000.0 1.04 0.6996 0.6701 2129057 PK04_108280 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O05 compound treatment 574372.0 -26100.0 -0.19 831775.0 191000.0 1.45 0.8913 0.6088 3188796 PK04_108281 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O06 compound treatment 603591.0 3090.0 0.02 787692.0 147000.0 1.12 0.8056 0.7213 2129061 PK04_108282 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O07 compound treatment 578192.0 -22300.0 -0.16 657026.0 16300.0 0.12 -0.0276 -0.1348 3071060 PK04_108283 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O08 compound treatment 606651.0 6150.0 0.04 727129.0 86400.0 0.66 0.4961 0.7538 2129067 PK04_108284 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O09 compound treatment 693678.0 93200.0 0.68 794582.0 154000.0 1.17 1.3085 0.967 3188797 PK04_108285 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O10 compound treatment 785759.0 185000.0 1.35 876450.0 236000.0 1.79 2.2244 0.9905 2129068 PK04_108286 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O11 mock treatment 651720.0 51200.0 0.37 723295.0 82600.0 0.63 0.7086 0.9696 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O12 mock treatment 637956.0 37500.0 0.27 585310.0 -55400.0 -0.42 -0.1038 -0.2068 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O13 compound treatment 649735.0 49200.0 0.36 756196.0 116000.0 0.88 0.875 0.9226 3188798 PK04_108287 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O14 compound treatment 649146.0 48600.0 0.36 605678.0 -35000.0 -0.27 0.0635 0.1429 3071064 PK04_108288 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O15 compound treatment 642136.0 41600.0 0.3 694869.0 54200.0 0.41 0.5063 0.989 3188799 PK04_108289 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O16 compound treatment 646677.0 46200.0 0.34 860800.0 220000.0 1.67 1.4211 0.8331 2133032 PK04_108290 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O17 compound treatment 569616.0 -30900.0 -0.23 755052.0 114000.0 0.87 0.4546 0.5064 3071066 PK04_108291 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O18 compound treatment 645043.0 44500.0 0.33 636212.0 -4480.0 -0.03 0.2063 0.6298 2133035 PK04_108292 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O19 compound treatment 655635.0 55100.0 0.4 668818.0 28100.0 0.21 0.4362 0.9559 3071068 PK04_108293 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O20 compound treatment 611724.0 11200.0 0.08 697736.0 57000.0 0.43 0.3645 0.8263 2133267 PK04_108294 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O21 compound treatment 645077.0 44600.0 0.33 721103.0 80400.0 0.61 0.6624 0.9567 3071112 PK04_108295 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O22 compound treatment 567506.0 -33000.0 -0.24 767398.0 127000.0 0.96 0.51 0.5139 2133153 PK04_108296 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O23 compound treatment 636957.0 36500.0 0.27 645749.0 5060.0 0.04 0.2157 0.8007 3188804 PK04_108297 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 O24 compound treatment 621351.0 20800.0 0.15 687957.0 47300.0 0.36 0.3617 0.9272 2132929 PK04_108298 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P01 compound treatment 710036.0 110000.0 0.8 743008.0 102000.0 0.78 1.116 0.9999 3188805 PK04_108299 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P02 compound treatment 688036.0 87500.0 0.64 831364.0 191000.0 1.45 1.4769 0.9326 3071118 PK04_108300 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P03 compound treatment 649160.0 48700.0 0.36 737382.0 96700.0 0.73 0.771 0.9447 3188806 PK04_108301 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P04 compound treatment 701782.0 101000.0 0.74 830241.0 190000.0 1.44 1.5419 0.9522 3071120 PK04_108302 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P05 compound treatment 646789.0 46300.0 0.34 731918.0 91200.0 0.69 0.7294 0.9457 3188807 PK04_108303 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P06 compound treatment 641568.0 41100.0 0.3 761607.0 121000.0 0.92 0.8619 0.8918 3188808 PK04_108304 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P07 compound treatment 654990.0 54500.0 0.4 716430.0 75700.0 0.58 0.6886 0.9839 3071124 PK04_108305 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P08 compound treatment 682580.0 82100.0 0.6 733824.0 93100.0 0.71 0.9247 0.9967 3188923 PK04_108306 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P09 compound treatment 745779.0 145000.0 1.06 881377.0 241000.0 1.83 2.0441 0.9666 3188924 PK04_108307 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P10 compound treatment 708242.0 108000.0 0.79 683532.0 42800.0 0.33 0.7873 0.9235 3071127 PK04_108308 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P11 mock treatment 648788.0 48300.0 0.35 729104.0 88400.0 0.67 0.7246 0.9549 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P12 mock treatment 642398.0 41900.0 0.31 745948.0 105000.0 0.8 0.7821 0.9133 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P13 compound treatment 729785.0 129000.0 0.95 714079.0 73400.0 0.56 1.0628 0.9683 3188925 PK04_108309 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P14 compound treatment 596972.0 -3530.0 -0.03 664286.0 23600.0 0.18 0.1085 0.5991 3071425 PK04_108310 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P15 compound treatment 696759.0 96300.0 0.7 681430.0 40700.0 0.31 0.7166 0.9319 3188926 PK04_108311 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P16 compound treatment 645111.0 44600.0 0.33 628631.0 -12100.0 -0.09 0.1659 0.4896 3215868 PK04_108312 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P17 compound treatment 739859.0 139000.0 1.02 731148.0 90500.0 0.69 1.2065 0.9816 3188927 PK04_108313 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P18 compound treatment 581951.0 -18600.0 -0.14 640045.0 -648.0 0.0 -0.0994 -0.7323 3215866 PK04_108314 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P19 compound treatment 695842.0 95300.0 0.7 661751.0 21100.0 0.16 0.6061 0.8473 3071435 PK04_108315 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P20 compound treatment 669556.0 69100.0 0.51 641280.0 587.0 0.0 0.3602 0.7133 3071437 PK04_108316 OB1OC(CCc2ccccc2)CC=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P21 compound treatment 797056.0 197000.0 1.44 710140.0 69400.0 0.53 1.3895 0.9074 3188929 PK04_108317 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P22 compound treatment 730830.0 130000.0 0.95 707926.0 67200.0 0.51 1.0351 0.9573 3071483 PK04_108318 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P23 compound treatment 696499.0 96000.0 0.7 615029.0 -25700.0 -0.19 0.3586 0.4921 3188930 PK04_108319 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2108 P24 compound treatment 698833.0 98300.0 0.72 632903.0 -7790.0 -0.06 0.4666 0.6467 3071486 PK04_108320 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A01 compound treatment 516148.0 -116000.0 -0.84 524639.0 -81100.0 -0.62 -1.0331 -0.988 3131442 CMLD2_000001 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A02 compound treatment 497170.0 -134000.0 -0.98 550287.0 -55500.0 -0.42 -0.9934 -0.9284 3131443 CMLD2_000002 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A03 compound treatment 520012.0 -112000.0 -0.82 532468.0 -73300.0 -0.56 -0.971 -0.9826 3010137 CMLD2_000003 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A04 compound treatment 334921.0 -297000.0 -2.17 352008.0 -254000.0 -1.93 -2.8976 -0.9983 3131444 CMLD2_000004 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A05 compound treatment 271091.0 -361000.0 -2.64 328582.0 -277000.0 -2.11 -3.3535 -0.9938 3131445 CMLD2_000005 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A06 compound treatment 530846.0 -101000.0 -0.74 450547.0 -155000.0 -1.18 -1.3551 -0.9744 3010139 CMLD2_000006 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A07 compound treatment 609059.0 -22600.0 -0.17 529552.0 -76200.0 -0.58 -0.5262 -0.8741 3131446 CMLD2_000007 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A08 compound treatment 533529.0 -98100.0 -0.72 553906.0 -51800.0 -0.39 -0.786 -0.9601 3010141 CMLD2_000008 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A09 compound treatment 578178.0 -53500.0 -0.39 569710.0 -36000.0 -0.27 -0.4702 -0.9848 3010141 CMLD2_000009 COCn1c2ccccc2c3nnc(nc13)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A10 compound treatment 524245.0 -107000.0 -0.79 537545.0 -68200.0 -0.52 -0.9219 -0.9796 3010142 CMLD2_000010 CC(C)[C@H](O)C1=CCCCC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A11 compound treatment 596835.0 -34800.0 -0.25 616002.0 10200.0 0.08 -0.1251 -0.4696 3131447 CMLD2_000011 O=C(OCc1ccccc1)C(C2CCCC(=O)C2)C(=O)OCc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A12 compound treatment 600194.0 -31500.0 -0.23 599641.0 -6110.0 -0.05 -0.1956 -0.833 3010143 CMLD2_000012 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A13 mock treatment 649192.0 17500.0 0.13 571261.0 -34500.0 -0.26 -0.0947 -0.3245 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A14 mock treatment 629018.0 -2640.0 -0.02 546016.0 -59700.0 -0.45 -0.3346 -0.7366 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A15 compound treatment 607796.0 -23900.0 -0.17 644340.0 38600.0 0.29 0.0838 0.2458 3131448 CMLD2_000013 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A16 compound treatment 418609.0 -213000.0 -1.56 393620.0 -212000.0 -1.61 -2.2413 -0.9999 3131449 CMLD2_000014 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A17 compound treatment 581297.0 -50400.0 -0.37 557380.0 -48400.0 -0.37 -0.5203 -1.0 3010159 CMLD2_000015 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A18 mock treatment 635823.0 4160.0 0.03 617792.0 12000.0 0.09 0.0862 0.8942 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A19 compound treatment 639605.0 7940.0 0.06 584024.0 -21700.0 -0.17 -0.0757 -0.4324 3131450 CMLD2_000016 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A20 compound treatment 596494.0 -35200.0 -0.26 547603.0 -58200.0 -0.44 -0.4942 -0.9669 3010162 CMLD2_000017 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A21 compound treatment 675067.0 43400.0 0.32 668652.0 62900.0 0.48 0.5623 0.9803 3131451 CMLD2_000018 COc1ccc(OC[C@H]2Cc3c(nc4CCN(CCOc5ccccc5)Cc4c3CO2)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A22 compound treatment 634010.0 2350.0 0.02 609654.0 3900.0 0.03 0.0331 0.9664 3131452 CMLD2_000019 COC(=O)C1=C(C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A23 compound treatment 602405.0 -29300.0 -0.21 601338.0 -4420.0 -0.03 -0.175 -0.8081 3010166 CMLD2_000020 COc1cccc(c1)[C@H]2N[C@@H](CC[C@@H]2C)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 A24 compound treatment 574360.0 -57300.0 -0.42 572853.0 -32900.0 -0.25 -0.4731 -0.9695 3010168 CMLD2_000021 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)C)c3ccccc3)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B01 compound treatment 593238.0 -38400.0 -0.28 610091.0 4340.0 0.03 -0.1754 -0.62 3131453 CMLD2_000022 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B02 compound treatment 506530.0 -125000.0 -0.92 570016.0 -35700.0 -0.27 -0.8391 -0.879 3131569 CMLD2_000023 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B03 compound treatment 472660.0 -159000.0 -1.16 464583.0 -141000.0 -1.07 -1.5806 -0.9992 3131570 CMLD2_000024 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B04 compound treatment 617481.0 -14200.0 -0.1 471207.0 -135000.0 -1.02 -0.7961 -0.7749 3010172 CMLD2_000025 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B05 compound treatment 345716.0 -286000.0 -2.09 378952.0 -227000.0 -1.72 -2.697 -0.9954 3131571 CMLD2_000026 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B06 compound treatment 532483.0 -99200.0 -0.73 454807.0 -151000.0 -1.15 -1.3237 -0.9756 3010200 CMLD2_000027 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B07 compound treatment 558198.0 -73500.0 -0.54 582871.0 -22900.0 -0.17 -0.5028 -0.8905 3131572 CMLD2_000028 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B08 compound treatment 570725.0 -60900.0 -0.45 525083.0 -80700.0 -0.61 -0.7485 -0.9878 3010203 CMLD2_000029 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B09 compound treatment 575860.0 -55800.0 -0.41 550414.0 -55300.0 -0.42 -0.5858 -0.9999 3010205 CMLD2_000030 COC(=O)NC/C=C\c1nc(CC/C=C\C(=O)OC)co1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B10 compound treatment 677292.0 45600.0 0.33 584816.0 -20900.0 -0.16 0.1235 0.334 3131573 CMLD2_000031 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@H](O)c2c(=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B11 compound treatment 759622.0 128000.0 0.94 592008.0 -13700.0 -0.1 0.5878 0.6243 3010207 CMLD2_000032 CC1(C)OCC(CO1)C(O)C2=CCCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B12 compound treatment 575084.0 -56600.0 -0.41 562581.0 -43200.0 -0.33 -0.5245 -0.9934 3131574 CMLD2_000033 COC(=O)[C@H](C)NC(=O)[C@@H](C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B13 mock treatment 671180.0 39500.0 0.29 564270.0 -41500.0 -0.32 -0.0185 -0.0433 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B14 mock treatment 610558.0 -21100.0 -0.15 583103.0 -22700.0 -0.17 -0.2308 -0.9985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B15 compound treatment 620688.0 -11000.0 -0.08 621157.0 15400.0 0.12 0.026 0.1831 3010209 CMLD2_000034 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B16 compound treatment 585430.0 -46200.0 -0.34 552274.0 -53500.0 -0.41 -0.5264 -0.9958 2082484 CMLD2_000035 COC(=O)C(C1CCCC(=O)C1)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B17 compound treatment 639922.0 8260.0 0.06 613191.0 7440.0 0.06 0.0826 0.9994 3131575 CMLD2_000036 COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B18 mock treatment 620430.0 -11200.0 -0.08 570195.0 -35600.0 -0.27 -0.2491 -0.8822 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B19 compound treatment 670232.0 38600.0 0.28 552499.0 -53300.0 -0.4 -0.0866 -0.1757 3010212 CMLD2_000037 CO[C@@H]1[C@H](O)CO[C@H]1/C=C/c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B20 compound treatment 577508.0 -54200.0 -0.4 533010.0 -72700.0 -0.55 -0.6708 -0.9866 3131576 CMLD2_000038 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C[C@H](O)CN=[N+]=[N-])c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B21 compound treatment 647593.0 15900.0 0.12 592534.0 -13200.0 -0.1 0.0114 0.0738 3010215 CMLD2_000039 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B22 compound treatment 694905.0 63200.0 0.46 556476.0 -49300.0 -0.37 0.0623 0.1047 3131577 CMLD2_000040 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B23 compound treatment 582566.0 -49100.0 -0.36 573292.0 -32500.0 -0.25 -0.4283 -0.9832 3010186 CMLD2_000041 COc1ccc(cc1)c2ccccc2[C@@H]3N[C@@H](CC[C@H]3C)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 B24 compound treatment 641904.0 10200.0 0.07 605130.0 -626.0 0.0 0.0496 0.6609 3131578 CMLD2_000042 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCOC4=O)C(=O)CC)c5ccccc5)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C01 compound treatment 565255.0 -66400.0 -0.49 519195.0 -86600.0 -0.66 -0.8084 -0.9889 3131579 CMLD2_000043 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6cccc7ccccc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C02 compound treatment 569181.0 -62500.0 -0.46 544305.0 -61500.0 -0.47 -0.6532 -0.9999 3010248 CMLD2_000044 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C03 compound treatment 577920.0 -53700.0 -0.39 608292.0 2540.0 0.02 -0.2643 -0.6716 3131580 CMLD2_000045 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C04 compound treatment 490151.0 -142000.0 -1.03 502349.0 -103000.0 -0.79 -1.2873 -0.9908 3131581 CMLD2_000046 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3ccc4OCOc4c3)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C05 compound treatment 560891.0 -70800.0 -0.52 504065.0 -102000.0 -0.77 -0.9122 -0.981 3131582 CMLD2_000047 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C06 compound treatment 563150.0 -68500.0 -0.5 574721.0 -31000.0 -0.24 -0.521 -0.9409 3010252 CMLD2_000048 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C07 compound treatment 470025.0 -162000.0 -1.18 473152.0 -133000.0 -1.01 -1.5482 -0.9968 3131583 CMLD2_000049 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C08 compound treatment 518279.0 -113000.0 -0.83 538297.0 -67500.0 -0.51 -0.9487 -0.9732 3010254 CMLD2_000050 Cc1cc2N(CC(O)CN3CCCc4nc(C)c(C)cc34)CCCc2nc1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C09 compound treatment 362714.0 -269000.0 -1.97 353262.0 -252000.0 -1.92 -2.7471 -0.9999 3131584 CMLD2_000051 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C10 compound treatment 505330.0 -126000.0 -0.92 534744.0 -71000.0 -0.54 -1.0347 -0.9672 3010257 CMLD2_000052 Cc1cc2C(=O)[C@@H]3O[C@@H]3[C@@H](O)c2c(=O)o1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C11 mock treatment 616686.0 -15000.0 -0.11 615556.0 9800.0 0.07 -0.0248 -0.1873 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C12 mock treatment 586663.0 -45000.0 -0.33 492900.0 -113000.0 -0.86 -0.8389 -0.9135 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C13 compound treatment 609958.0 -21700.0 -0.16 541514.0 -64200.0 -0.49 -0.4573 -0.8911 3010259 CMLD2_000053 OC(CCOCc1ccccc1)C2=CCCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C14 compound treatment 559282.0 -72400.0 -0.53 544361.0 -61400.0 -0.47 -0.7041 -0.998 1304363 CMLD2_000054 C1Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C15 mock treatment 625670.0 -5990.0 -0.04 615246.0 9490.0 0.07 0.02 0.2369 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C16 mock treatment 652414.0 20800.0 0.15 654285.0 48500.0 0.37 0.368 0.923 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C17 compound treatment 499173.0 -132000.0 -0.97 494396.0 -111000.0 -0.85 -1.2833 -0.9977 3010233 CMLD2_000055 COc1ccc(cc1)c2cnnc(CCCn3ccnc3c4ccccc4)n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C18 compound treatment 590019.0 -41600.0 -0.3 544905.0 -60900.0 -0.46 -0.5422 -0.9795 3131585 CMLD2_000056 Cc1ccc(O[C@H]2C=C[C@@H](CC=C)O[C@@H]2COC(=O)NCc3cccc4ccccc34)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C19 compound treatment 297351.0 -334000.0 -2.44 320484.0 -285000.0 -2.17 -3.2612 -0.9982 3131586 CMLD2_000057 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2ccc(cc2)C(=O)OC)C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C20 compound treatment 623448.0 -8210.0 -0.06 503418.0 -102000.0 -0.78 -0.5922 -0.7595 3010236 CMLD2_000058 C[C@H]1CC[C@@H]2N(CC(CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C21 compound treatment 662979.0 31300.0 0.23 571582.0 -34200.0 -0.26 -0.0216 -0.0625 3131587 CMLD2_000059 CC(C)CN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2CC1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C22 compound treatment 613402.0 -18300.0 -0.13 576100.0 -29700.0 -0.23 -0.2537 -0.9688 3131703 CMLD2_000060 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C23 compound treatment 620469.0 -11200.0 -0.08 514125.0 -91600.0 -0.7 -0.5501 -0.7849 3010240 CMLD2_000061 OC(=O)[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 C24 compound treatment 589430.0 -42200.0 -0.31 496579.0 -109000.0 -0.83 -0.8049 -0.9094 3131704 CMLD2_000062 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C4=O)c5ccccc5)C(=O)OC)c6ccccc6)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D01 compound treatment 531038.0 -101000.0 -0.74 628756.0 23000.0 0.17 -0.3968 -0.5246 3010292 CMLD2_000063 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D02 compound treatment 516251.0 -115000.0 -0.84 485294.0 -120000.0 -0.92 -1.2439 -0.9992 3131705 CMLD2_000064 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D03 compound treatment 595882.0 -35800.0 -0.26 611909.0 6150.0 0.05 -0.152 -0.5717 3131706 CMLD2_000065 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D04 compound treatment 485975.0 -146000.0 -1.07 524660.0 -81100.0 -0.62 -1.189 -0.9661 3010296 CMLD2_000066 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D05 compound treatment 553676.0 -78000.0 -0.57 589657.0 -16100.0 -0.12 -0.4898 -0.8396 3010274 CMLD2_000067 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D06 compound treatment 563678.0 -68000.0 -0.5 528678.0 -77100.0 -0.59 -0.7656 -0.9967 3131707 CMLD2_000068 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D07 compound treatment 538492.0 -93200.0 -0.68 532560.0 -73200.0 -0.56 -0.875 -0.9949 3131708 CMLD2_000069 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D08 compound treatment 610426.0 -21200.0 -0.16 621688.0 15900.0 0.12 -0.0242 -0.1231 3010278 CMLD2_000070 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D09 compound treatment 564141.0 -67500.0 -0.49 468280.0 -137000.0 -1.04 -1.0876 -0.9415 3010279 CMLD2_000071 CN1CCN(CC(O)CN2CCCc3nc(C)c(C)cc23)CC1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D10 compound treatment 636913.0 5250.0 0.04 553419.0 -52300.0 -0.4 -0.254 -0.6359 3131709 CMLD2_000072 C[C@@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D11 mock treatment 623162.0 -8500.0 -0.06 526757.0 -79000.0 -0.6 -0.4683 -0.7762 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D12 mock treatment 653969.0 22300.0 0.16 506563.0 -99200.0 -0.75 -0.4175 -0.5415 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D13 compound treatment 610158.0 -21500.0 -0.16 567334.0 -38400.0 -0.29 -0.3176 -0.9579 3010281 CMLD2_000073 Brc1ccc(cc1)C(=O)OC(CCc2ccccc2)C3=CCCCC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D14 compound treatment 567840.0 -63800.0 -0.47 555554.0 -50200.0 -0.38 -0.5997 -0.995 3131710 CMLD2_000074 CCOC(=O)CC(C1CCCCC1=O)C(=O)OCC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D15 mock treatment 541694.0 -90000.0 -0.66 584113.0 -21600.0 -0.16 -0.5815 -0.8574 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D16 mock treatment 606884.0 -24800.0 -0.18 622849.0 17100.0 0.13 -0.0363 -0.1629 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D17 compound treatment 548334.0 -83300.0 -0.61 613040.0 7280.0 0.06 -0.3918 -0.6403 3131711 CMLD2_000075 COC(=O)C/C=C/[C@H](C)[C@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D18 compound treatment 470943.0 -161000.0 -1.18 547622.0 -58100.0 -0.44 -1.1434 -0.9106 3010283 CMLD2_000076 CCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D19 compound treatment 588311.0 -43400.0 -0.32 454968.0 -151000.0 -1.15 -1.0342 -0.8701 3131712 CMLD2_000077 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D20 compound treatment 633164.0 1500.0 0.01 647541.0 41800.0 0.32 0.2322 0.7311 3010285 CMLD2_000078 COC(=O)[C@@H]1CC[C@@H](C)[C@@H](N1)c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D21 compound treatment 586172.0 -45500.0 -0.33 621056.0 15300.0 0.12 -0.1531 -0.4343 3131713 CMLD2_000079 C[C@@H]1Cc2c(CO1)cnc3CCN(C)Cc32 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D22 compound treatment 599449.0 -32200.0 -0.24 574289.0 -31500.0 -0.24 -0.3356 -1.0 3131714 CMLD2_000080 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D23 compound treatment 584451.0 -47200.0 -0.35 503597.0 -102000.0 -0.78 -0.7929 -0.9335 3010288 CMLD2_000081 COc1cc(cc(OC)c1OC)[C@@H]2N[C@@H](Cc3c2[nH]c4ccccc34)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 D24 compound treatment 672239.0 40600.0 0.3 630744.0 25000.0 0.19 0.3441 0.9767 3131715 CMLD2_000082 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E01 mock treatment 520719.0 -111000.0 -0.81 601856.0 -3900.0 -0.03 -0.5947 -0.7324 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E02 mock treatment 485951.0 -146000.0 -1.07 602116.0 -3640.0 -0.03 -0.7731 -0.7252 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E03 compound treatment 492930.0 -139000.0 -1.01 482409.0 -123000.0 -0.94 -1.38 -0.9992 3010304 CMLD2_000083 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E04 compound treatment 567361.0 -64300.0 -0.47 546173.0 -59600.0 -0.45 -0.6526 -0.9998 3131716 CMLD2_000084 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E05 compound treatment 590190.0 -41500.0 -0.3 574222.0 -31500.0 -0.24 -0.3839 -0.9932 3131717 CMLD2_000085 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E06 compound treatment 495750.0 -136000.0 -0.99 468720.0 -137000.0 -1.04 -1.4389 -0.9997 3010306 CMLD2_000086 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E07 compound treatment 568711.0 -63000.0 -0.46 558200.0 -47600.0 -0.36 -0.581 -0.9928 3131718 CMLD2_000087 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E08 compound treatment 548157.0 -83500.0 -0.61 574922.0 -30800.0 -0.23 -0.5975 -0.9134 3131719 CMLD2_000088 Brc1ccc(cc1)c2ccc3N(CCCc3n2)C(=O)NCCCN4=CC=NC4c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E09 mock treatment 498507.0 -133000.0 -0.97 622084.0 16300.0 0.12 -0.6009 -0.6121 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E10 mock treatment 650741.0 19100.0 0.14 575502.0 -30300.0 -0.23 -0.0639 -0.2375 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E11 compound treatment 518312.0 -113000.0 -0.83 559859.0 -45900.0 -0.35 -0.8327 -0.926 3010320 CMLD2_000089 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)NCc3cccc4ccccc34)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E12 compound treatment 659015.0 27400.0 0.2 612114.0 6360.0 0.05 0.1756 0.8533 3131720 CMLD2_000090 CC(C)C(=O)N[C@H]1CCCN1C(=O)/C=C/c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E13 compound treatment 540957.0 -90700.0 -0.66 483445.0 -122000.0 -0.93 -1.1261 -0.9864 3010323 CMLD2_000091 OC(COCc1ccccc1)C2=CCCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E14 compound treatment 351065.0 -281000.0 -2.05 344442.0 -261000.0 -1.99 -2.8547 -0.9999 3131721 CMLD2_000092 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3ccccc3O[C@]2([C@@H]1c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E15 compound treatment 565395.0 -66300.0 -0.48 496122.0 -110000.0 -0.83 -0.9316 -0.9668 3010326 CMLD2_000093 COc1cc(O)c(C(=O)/C=C/c2ccc3OCOc3c2)c(OC)c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E16 mock treatment 658619.0 27000.0 0.2 678119.0 72400.0 0.55 0.5281 0.9043 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E17 mock treatment 623063.0 -8600.0 -0.06 521945.0 -83800.0 -0.64 -0.4947 -0.7732 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E18 mock treatment 585799.0 -45900.0 -0.34 664242.0 58500.0 0.44 0.077 0.1383 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E19 compound treatment 608655.0 -23000.0 -0.17 635250.0 29500.0 0.22 0.0395 0.1408 3131722 CMLD2_000094 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E20 compound treatment 647023.0 15400.0 0.11 510232.0 -95500.0 -0.73 -0.4337 -0.5906 3131840 CMLD2_000095 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)C(F)(F)F)c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E21 compound treatment 711934.0 80300.0 0.59 574371.0 -31400.0 -0.24 0.2465 0.389 3010332 CMLD2_000096 C1Cc2nc(c3ccccc3)c(cc2CN1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E22 compound treatment 673742.0 42100.0 0.31 526069.0 -79700.0 -0.61 -0.2105 -0.3099 3131841 CMLD2_000097 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCOC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E23 compound treatment 552034.0 -79600.0 -0.58 592335.0 -13400.0 -0.1 -0.4839 -0.8185 3010340 CMLD2_000098 C[C@H]1CC[C@H](N[C@@H]1c2cccc(CC=C)c2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 E24 compound treatment 608238.0 -23400.0 -0.17 559568.0 -46200.0 -0.35 -0.3692 -0.9456 3131842 CMLD2_000099 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3CCCC4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F01 mock treatment 576189.0 -55500.0 -0.41 615344.0 9590.0 0.07 -0.2354 -0.571 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F02 mock treatment 616114.0 -15500.0 -0.11 570301.0 -35500.0 -0.27 -0.2709 -0.9265 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F03 compound treatment 422381.0 -209000.0 -1.53 476272.0 -129000.0 -0.98 -1.7778 -0.9772 3131843 CMLD2_000100 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F04 compound treatment 533366.0 -98300.0 -0.72 497540.0 -108000.0 -0.82 -1.0896 -0.9978 3010347 CMLD2_000101 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F05 compound treatment 618884.0 -12800.0 -0.09 636589.0 30800.0 0.23 0.0995 0.3947 3131844 CMLD2_000102 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F06 compound treatment 496572.0 -135000.0 -0.99 639086.0 33300.0 0.25 -0.5195 -0.5094 3131845 CMLD2_000103 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F07 compound treatment 483457.0 -148000.0 -1.08 434737.0 -171000.0 -1.3 -1.6851 -0.9959 3011245 CMLD2_000104 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F08 compound treatment 641387.0 9720.0 0.07 572358.0 -33400.0 -0.25 -0.1291 -0.49 3010203 CMLD2_000105 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCc2nc1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F09 mock treatment 513702.0 -118000.0 -0.86 575475.0 -30300.0 -0.23 -0.7727 -0.8654 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F10 mock treatment 526214.0 -105000.0 -0.77 502853.0 -103000.0 -0.78 -1.0981 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F11 compound treatment 637133.0 5470.0 0.04 649973.0 44200.0 0.34 0.2658 0.7858 3011246 CMLD2_000106 C[C@@]12CCC3C(CCc4cc(OCC5CO5)ccc34)C2CC[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F12 compound treatment 506807.0 -125000.0 -0.91 600159.0 -5600.0 -0.04 -0.6757 -0.7392 3011247 CMLD2_000107 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F13 compound treatment 620686.0 -11000.0 -0.08 609710.0 3950.0 0.03 -0.0355 -0.4144 3131846 CMLD2_000108 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(Br)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F14 compound treatment 541790.0 -89900.0 -0.66 616403.0 10600.0 0.08 -0.4076 -0.6154 3011248 CMLD2_000109 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F15 compound treatment 620798.0 -10900.0 -0.08 549556.0 -56200.0 -0.43 -0.3581 -0.8245 1946418 CMLD2_000110 Fc1ccc(cc1)C(=O)/C=C/c2ccc3OCOc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F16 compound treatment 573740.0 -57900.0 -0.42 613088.0 7330.0 0.06 -0.2601 -0.6089 3011250 CMLD2_000111 OC(CCOC(c1ccccc1)(c2ccccc2)c3ccccc3)C4=CCCCC4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F17 mock treatment 555732.0 -75900.0 -0.56 555330.0 -50400.0 -0.38 -0.6635 -0.9836 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F18 mock treatment 679379.0 47700.0 0.35 530222.0 -75500.0 -0.57 -0.159 -0.2368 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F19 compound treatment 603973.0 -27700.0 -0.2 602116.0 -3640.0 -0.03 -0.1627 -0.7963 3131847 CMLD2_000112 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F20 compound treatment 654492.0 22800.0 0.17 549795.0 -56000.0 -0.43 -0.1826 -0.3997 3131848 CMLD2_000113 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1)c2ccc(Br)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F21 compound treatment 695331.0 63700.0 0.47 558405.0 -47400.0 -0.36 0.0749 0.1273 3011251 CMLD2_000114 CN1CCc2nc(CO)c(CO)cc2C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F22 compound treatment 639393.0 7730.0 0.06 637286.0 31500.0 0.24 0.2093 0.8506 3131849 CMLD2_000115 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F23 compound treatment 565811.0 -65900.0 -0.48 502751.0 -103000.0 -0.78 -0.8938 -0.9728 3011252 CMLD2_000116 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(c3)N4CCOCC4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6cccc(c6)N7CCOCC7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 F24 compound treatment 607998.0 -23700.0 -0.17 513865.0 -91900.0 -0.7 -0.616 -0.8565 3131850 CMLD2_000117 CCN1C(=C([C@H](N2C(=O)[C@]3(O[C@]21[C@H]4[C@@H]3C(=O)N(C)C4=O)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G01 compound treatment 572688.0 -59000.0 -0.43 538409.0 -67300.0 -0.51 -0.6667 -0.9964 3131851 CMLD2_000118 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCN3CCOCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G02 compound treatment 577436.0 -54200.0 -0.4 542865.0 -62900.0 -0.48 -0.6182 -0.9957 3131852 CMLD2_000119 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G03 mock treatment 623843.0 -7820.0 -0.06 516420.0 -89300.0 -0.68 -0.5203 -0.764 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G04 mock treatment 483285.0 -148000.0 -1.09 547543.0 -58200.0 -0.44 -1.08 -0.9217 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G05 compound treatment 595297.0 -36400.0 -0.27 483820.0 -122000.0 -0.93 -0.8431 -0.8748 3011253 CMLD2_000120 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G06 compound treatment 570863.0 -60800.0 -0.44 666846.0 61100.0 0.46 0.0138 0.0214 3131853 CMLD2_000121 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G07 compound treatment 538707.0 -93000.0 -0.68 491312.0 -114000.0 -0.87 -1.0955 -0.9926 3011254 CMLD2_000122 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)OC2CC(CCC3CC(=NO3)CC)OC4(CCCC(COC(=O)NCCC(C)C)O4)C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G08 compound treatment 534216.0 -97400.0 -0.71 537855.0 -67900.0 -0.52 -0.8687 -0.9874 3131854 CMLD2_000123 Cc1ccc(cc1)S(=O)(=O)NC(CCc2ccccc2)CC(=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G09 compound treatment 618791.0 -12900.0 -0.09 630772.0 25000.0 0.19 0.0678 0.3198 3131855 CMLD2_000124 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)N3CCCCC3)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G10 compound treatment 644147.0 12500.0 0.09 581001.0 -24800.0 -0.19 -0.0684 -0.3273 3011255 CMLD2_000125 O[C@H]1C=C(C=C)C2(OCCCO2)[C@H]3O[C@H]31 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G11 compound treatment 581426.0 -50200.0 -0.37 588199.0 -17600.0 -0.13 -0.3541 -0.906 3011256 CMLD2_000126 OC(CCc1ccccc1)C2=CCCOC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G12 compound treatment 504967.0 -127000.0 -0.93 440168.0 -166000.0 -1.26 -1.5447 -0.9887 3131856 CMLD2_000127 C[C@H]1OC=C2[C@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](OC(=O)C)[C@H]7O[C@H]7C6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G13 compound treatment 572865.0 -58800.0 -0.43 636061.0 30300.0 0.23 -0.1413 -0.2896 3011257 CMLD2_000128 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G14 compound treatment 563698.0 -68000.0 -0.5 521335.0 -84400.0 -0.64 -0.8049 -0.9921 3131857 CMLD2_000129 CC/C=C\CCC(OC(=O)c1ccc(Br)cc1)C2=CCCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G15 compound treatment 513707.0 -118000.0 -0.86 471269.0 -134000.0 -1.02 -1.3324 -0.9965 3011258 CMLD2_000130 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G16 mock treatment 680346.0 48700.0 0.36 536532.0 -69200.0 -0.53 -0.1201 -0.1891 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G17 compound treatment 659685.0 28000.0 0.2 531865.0 -73900.0 -0.56 -0.252 -0.4217 3131858 CMLD2_000131 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G18 compound treatment 403076.0 -229000.0 -1.67 405673.0 -200000.0 -1.52 -2.2568 -0.9989 3131859 CMLD2_000132 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G19 mock treatment 645803.0 14100.0 0.1 621772.0 16000.0 0.12 0.1592 0.9967 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G20 mock treatment 651622.0 20000.0 0.15 620311.0 14600.0 0.11 0.1814 0.9906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G21 compound treatment 691003.0 59300.0 0.43 573688.0 -32100.0 -0.24 0.1346 0.2705 3011259 CMLD2_000133 CN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G22 compound treatment 564912.0 -66800.0 -0.49 650966.0 45200.0 0.34 -0.1023 -0.1714 3131977 CMLD2_000134 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G23 compound treatment 526483.0 -105000.0 -0.77 568185.0 -37600.0 -0.29 -0.7457 -0.9089 3011260 CMLD2_000135 C[C@H]1CC[C@@H]2N([C@@H]1c3cccc(CC=C)c3)C(=O)[C@@H]4CC[C@H](C)[C@H](N4C2=O)c5cccc(CC=C)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 G24 compound treatment 592150.0 -39500.0 -0.29 552373.0 -53400.0 -0.41 -0.4911 -0.9862 3131978 CMLD2_000136 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H01 compound treatment 623414.0 -8250.0 -0.06 582780.0 -23000.0 -0.17 -0.1661 -0.8993 3131979 CMLD2_000137 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H02 compound treatment 601636.0 -30000.0 -0.22 640726.0 35000.0 0.27 0.0326 0.0945 3131980 CMLD2_000138 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H03 mock treatment 579411.0 -52300.0 -0.38 645887.0 40100.0 0.3 -0.0546 -0.1118 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H04 mock treatment 605501.0 -26200.0 -0.19 647129.0 41400.0 0.31 0.087 0.2363 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H05 compound treatment 644835.0 13200.0 0.1 598982.0 -6770.0 -0.05 0.0317 0.2905 3011261 CMLD2_000139 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H06 compound treatment 380081.0 -252000.0 -1.84 408863.0 -197000.0 -1.5 -2.3586 -0.9947 3131981 CMLD2_000140 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H07 compound treatment 453099.0 -179000.0 -1.31 357731.0 -248000.0 -1.88 -2.2557 -0.984 3422360 CMLD2_000141 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H08 compound treatment 646766.0 15100.0 0.11 596521.0 -9230.0 -0.07 0.0285 0.2178 3010278 CMLD2_000142 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(ccc45)c6ccc(Br)cc6)CCCc3n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H09 compound treatment 628047.0 -3620.0 -0.03 689158.0 83400.0 0.63 0.4293 0.677 3011262 CMLD2_000143 CON(C)C(=O)c1nnc2c3ccccc3[nH]c2n1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H10 compound treatment 514419.0 -117000.0 -0.86 554779.0 -51000.0 -0.39 -0.8801 -0.9355 3011263 CMLD2_000144 C/C=C/C1=C(CO)C(=O)[C@@H]2O[C@@H]2C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H11 compound treatment 576772.0 -54900.0 -0.4 647019.0 41300.0 0.31 -0.0622 -0.1221 3011264 CMLD2_000145 CCOC(=O)CC(CC(=O)C)C(=O)OCC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H12 compound treatment 565022.0 -66600.0 -0.49 635284.0 29500.0 0.22 -0.186 -0.3467 3131982 CMLD2_000146 CCOC(=O)C1=NO[C@@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H13 compound treatment 646287.0 14600.0 0.11 550706.0 -55000.0 -0.42 -0.2201 -0.5099 3011265 CMLD2_000147 OC(C1CCCCC1)C2=CCCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H14 compound treatment 578309.0 -53400.0 -0.39 644495.0 38700.0 0.29 -0.0678 -0.1387 3011266 CMLD2_000148 OC(C1=CCCCC1=O)c2ccc(cc2)[N+](=O)[O-] 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H15 compound treatment 607485.0 -24200.0 -0.18 629572.0 23800.0 0.18 0.0029 0.0115 3131983 CMLD2_000149 CC1(C)O[C@H]2OC([C@H](O)CON3C(=O)c4ccccc4C3=O)[C@H](O)[C@H]2O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H16 compound treatment 548100.0 -83600.0 -0.61 608419.0 2660.0 0.02 -0.4178 -0.6833 3011267 CMLD2_000150 COCOc1ccc(Br)cc1C(=O)[C@@H]2O[C@H]2c3cccc(OC)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H17 compound treatment 593426.0 -38200.0 -0.28 650532.0 44800.0 0.34 0.0428 0.0972 3131984 CMLD2_000151 C[C@@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@]42[C@H]5O[C@H](C)[C@@H]([C@@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H18 compound treatment 642844.0 11200.0 0.08 673081.0 67300.0 0.51 0.4195 0.8099 3011268 CMLD2_000152 COc1ccc(C#C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H19 mock treatment 650164.0 18500.0 0.14 622395.0 16600.0 0.13 0.1851 0.9994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H20 mock treatment 581207.0 -50500.0 -0.37 664522.0 58800.0 0.45 0.0548 0.0945 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H21 compound treatment 638485.0 6820.0 0.05 639301.0 33500.0 0.25 0.2155 0.8298 3131985 CMLD2_000153 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H22 compound treatment 711624.0 80000.0 0.58 683748.0 78000.0 0.59 0.8324 1.0 3131715 CMLD2_000154 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]([C@@H]3C(=O)c5ccccc5)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H23 compound treatment 596246.0 -35400.0 -0.26 603491.0 -2260.0 -0.02 -0.1953 -0.7524 3011247 CMLD2_000155 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(cc3)c4ccco4)C(=O)[C@@H]5CC[C@@H](C)[C@@H](N5C2=O)c6ccc(cc6)c7ccco7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 H24 compound treatment 664319.0 32700.0 0.24 619838.0 14100.0 0.11 0.2445 0.9344 3131986 CMLD2_000156 COC(=O)C1=C(C)N(Cc2ccccc2)c3c(C(=O)OC)c(C(=O)OC)c(C(=O)OC)c(=O)n3[C@@H]1c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I01 compound treatment 571948.0 -59700.0 -0.44 556345.0 -49400.0 -0.38 -0.5742 -0.9972 3131987 CMLD2_000157 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I02 compound treatment 682874.0 51200.0 0.37 703800.0 98000.0 0.74 0.7915 0.9494 3011269 CMLD2_000158 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCc3cccc4ccccc34)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I03 compound treatment 600582.0 -31100.0 -0.23 577672.0 -28100.0 -0.21 -0.3116 -0.9995 3131988 CMLD2_000159 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I04 compound treatment 500789.0 -131000.0 -0.96 709459.0 104000.0 0.79 -0.1197 -0.0966 3011270 CMLD2_000160 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I05 mock treatment 681272.0 49600.0 0.36 547172.0 -58600.0 -0.45 -0.0582 -0.1013 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I06 mock treatment 579633.0 -52000.0 -0.38 633726.0 28000.0 0.21 -0.1188 -0.2726 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I07 compound treatment 614839.0 -16800.0 -0.12 565523.0 -40200.0 -0.31 -0.3031 -0.92 3422373 CMLD2_000161 CCC1=NOC(CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5cccc6OCOc65)C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I08 compound treatment 635919.0 4260.0 0.03 674703.0 68900.0 0.52 0.3924 0.7478 3011271 CMLD2_000162 COC(=O)NC/C=C\c1nc(CCCO)co1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I09 compound treatment 672747.0 41100.0 0.3 666244.0 60500.0 0.46 0.5374 0.9788 3131989 CMLD2_000163 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I10 compound treatment 615267.0 -16400.0 -0.12 550989.0 -54800.0 -0.42 -0.379 -0.8753 3011272 CMLD2_000164 CO[C@@H]1[C@@H](C)/C(=C\CC(=O)OC)/c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I11 compound treatment 646524.0 14900.0 0.11 672079.0 66300.0 0.5 0.4331 0.8403 3131990 CMLD2_000165 CC(=NOCc1ccc(cc1)c2cc(no2)c3ccccc3)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I12 compound treatment 633247.0 1580.0 0.01 712810.0 107000.0 0.81 0.5833 0.7171 3131991 CMLD2_000166 COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I13 compound treatment 774976.0 143000.0 1.05 680182.0 74400.0 0.57 1.1409 0.9581 3011273 CMLD2_000167 C=CC(=O)N1C(=O)c2ccccc2S1(=O)=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I14 compound treatment 432972.0 -199000.0 -1.45 372754.0 -233000.0 -1.77 -2.2791 -0.9952 3131992 CMLD2_000168 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#Cc3ccccc3)cc2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I15 compound treatment 653922.0 22300.0 0.16 684382.0 78600.0 0.6 0.5375 0.8682 3011274 CMLD2_000169 CC(C)OC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I16 mock treatment 627491.0 -4170.0 -0.03 653370.0 47600.0 0.36 0.2342 0.6452 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I17 compound treatment 429656.0 -202000.0 -1.48 492652.0 -113000.0 -0.86 -1.6522 -0.9667 3131993 CMLD2_000170 C[C@H]1OC=C2[C@H](O)C3O[C@@H]3/C(=N\OCc4ccccc4)/[C@@]52[C@H]6OC(C)[C@@H](C15)C7=C6[C@H](O)[C@H]8O[C@H]8C7=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I18 compound treatment 645176.0 13500.0 0.1 554202.0 -51600.0 -0.39 -0.2071 -0.5126 3011312 CMLD2_000171 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCCc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I19 compound treatment 579251.0 -52400.0 -0.38 593625.0 -12100.0 -0.09 -0.3362 -0.8528 3131989 CMLD2_000172 CCCC[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I20 compound treatment 614760.0 -16900.0 -0.12 674929.0 69200.0 0.53 0.2842 0.5264 3011257 CMLD2_000173 C[C@@H]1CC[C@@H]2N(C[C@H](O)CNC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I21 mock treatment 590782.0 -40900.0 -0.3 596557.0 -9200.0 -0.07 -0.2608 -0.8495 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I22 mock treatment 651351.0 19700.0 0.14 554636.0 -51100.0 -0.39 -0.1728 -0.4172 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I23 compound treatment 668600.0 36900.0 0.27 621715.0 16000.0 0.12 0.2767 0.9346 3132111 CMLD2_000174 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(NC(=O)C)cc3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5ccc(NC(=O)C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 I24 compound treatment 635564.0 3900.0 0.03 538874.0 -66900.0 -0.51 -0.3391 -0.6664 3131703 CMLD2_000175 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C5=O)c6ccccc6)C(=O)OC)N([C@@H]1c7ccccc7)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J01 compound treatment 585920.0 -45700.0 -0.33 476560.0 -129000.0 -0.98 -0.9305 -0.8974 3132112 CMLD2_000176 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J02 compound treatment 427083.0 -205000.0 -1.5 476995.0 -129000.0 -0.98 -1.7496 -0.9788 3011347 CMLD2_000177 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J03 compound treatment 626640.0 -5020.0 -0.04 616352.0 10600.0 0.08 0.0309 0.3497 3132113 CMLD2_000178 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J04 compound treatment 563608.0 -68100.0 -0.5 697541.0 91800.0 0.7 0.1411 0.1647 3132114 CMLD2_000179 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J05 mock treatment 692522.0 60900.0 0.45 680709.0 75000.0 0.57 0.7173 0.9926 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J06 mock treatment 678097.0 46400.0 0.34 674115.0 68400.0 0.52 0.6073 0.9788 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J07 compound treatment 573976.0 -57700.0 -0.42 581433.0 -24300.0 -0.18 -0.429 -0.9314 3011348 CMLD2_000180 CC(C)C[C@H](NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45)C(=O)NCC(c6ccccc6)c7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J08 compound treatment 453823.0 -178000.0 -1.3 537322.0 -68400.0 -0.52 -1.2872 -0.9191 3132115 CMLD2_000181 CO[C@H]1C[C@@H]2C[C@H](CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2)OC(=O)\C=C/CCc4coc(\C=C/CNC(=O)OC)n4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J09 compound treatment 656450.0 24800.0 0.18 667923.0 62200.0 0.47 0.4621 0.9135 3011349 CMLD2_000182 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J10 compound treatment 568834.0 -62800.0 -0.46 601265.0 -4490.0 -0.03 -0.349 -0.7575 3132116 CMLD2_000183 CO[C@@H](C(C)C)[C@@H](C)C1OC(=O)CC1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J11 compound treatment 697445.0 65800.0 0.48 571991.0 -33800.0 -0.26 0.1588 0.2913 3132117 CMLD2_000184 COC(=O)[C@@H]1[C@@H](c2ccccc2)[C@](Oc3ccccc3C1=O)(C(=O)OC)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J12 compound treatment 648622.0 17000.0 0.12 601122.0 -4630.0 -0.04 0.0628 0.4872 3011350 CMLD2_000185 CC(=NOCc1cccc(c1)c2cc(no2)c3ccccc3)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J13 compound treatment 634742.0 3080.0 0.02 704394.0 98600.0 0.75 0.5458 0.728 3132118 CMLD2_000186 CC(C)C(=O)N[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J14 compound treatment 616131.0 -15500.0 -0.11 705027.0 99300.0 0.75 0.4529 0.5939 3011352 CMLD2_000187 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C=C)cc2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J15 compound treatment 693345.0 61700.0 0.45 666839.0 61100.0 0.46 0.6471 0.9999 3132119 CMLD2_000188 CO[C@H](CO)COc1ccc(OC)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J16 compound treatment 584824.0 -46800.0 -0.34 695106.0 89400.0 0.68 0.2378 0.3127 3011353 CMLD2_000189 Oc1ccccc1C(=O)/C=C/c2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J17 compound treatment 609179.0 -22500.0 -0.16 671866.0 66100.0 0.5 0.2389 0.452 3132120 CMLD2_000190 CC(=NOCc1ccc(cc1)c2cn(nn2)[C@@H]3COC[C@H]3O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J18 compound treatment 585043.0 -46600.0 -0.34 605855.0 99.2 0.0 -0.2405 -0.7055 3011354 CMLD2_000191 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J19 compound treatment 604116.0 -27500.0 -0.2 685997.0 80200.0 0.61 0.2886 0.4495 3132121 CMLD2_000192 C[C@@H]1CC[C@@H]2N(CC(COCC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J20 compound treatment 720370.0 88700.0 0.65 735337.0 130000.0 0.98 1.1548 0.9795 3011355 CMLD2_000193 CC(C)CCN1CCc2nc(c3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J21 mock treatment 696212.0 64500.0 0.47 676059.0 70300.0 0.53 0.7114 0.9981 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J22 mock treatment 651588.0 19900.0 0.15 514825.0 -90900.0 -0.69 -0.3854 -0.5459 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J23 compound treatment 647548.0 15900.0 0.12 641212.0 35500.0 0.27 0.2726 0.9293 3132122 CMLD2_000194 C[C@@H]1CC[C@@H]2N([C@H]1c3cccc(Br)c3)C(=O)[C@@H]4CC[C@@H](C)[C@@H](N4C2=O)c5cccc(c5)N6CCOCC6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 J24 compound treatment 603855.0 -27800.0 -0.2 566154.0 -39600.0 -0.3 -0.3565 -0.9818 3132123 CMLD2_000195 CCC(=O)[C@@]1(O[C@@]23[C@H]4[C@@H]1CCOC4=O)C(=O)N3[C@@H](C(=C(C)N2Cc5ccccc5)C(=O)OC)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K01 compound treatment 619346.0 -12300.0 -0.09 536544.0 -69200.0 -0.53 -0.4355 -0.8164 3132124 CMLD2_000196 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K02 compound treatment 636051.0 4390.0 0.03 673228.0 67500.0 0.51 0.3851 0.7499 3011357 CMLD2_000197 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K03 compound treatment 628886.0 -2780.0 -0.02 589851.0 -15900.0 -0.12 -0.0998 -0.8145 3132125 CMLD2_000198 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K04 compound treatment 515542.0 -116000.0 -0.85 526125.0 -79600.0 -0.6 -1.0282 -0.9862 3132126 CMLD2_000199 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCCc6ccc(F)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K05 compound treatment 610883.0 -20800.0 -0.15 737580.0 132000.0 1.0 0.6007 0.593 3011359 CMLD2_000200 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K06 compound treatment 657542.0 25900.0 0.19 672425.0 66700.0 0.51 0.492 0.9099 3132127 CMLD2_000201 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccccc4OC)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K07 mock treatment 635005.0 3340.0 0.02 744312.0 139000.0 1.05 0.7616 0.7233 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K08 mock treatment 672418.0 40800.0 0.3 728933.0 123000.0 0.94 0.8724 0.8884 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K09 compound treatment 689782.0 58100.0 0.43 588174.0 -17600.0 -0.13 0.2061 0.4626 3011360 CMLD2_000202 COc1cccc(c1)[C@H](O)Cn2cc(nn2)c3ccc(CON=C(C)C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K10 compound treatment 632757.0 1090.0 0.01 571113.0 -34600.0 -0.26 -0.1804 -0.6853 3132128 CMLD2_000203 Cc1ccc2[nH]c3nc(CCCn4ccnc4c5ccccc5)nnc3c2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K11 compound treatment 661160.0 29500.0 0.22 630815.0 25100.0 0.19 0.2871 0.9981 3011361 CMLD2_000204 COC(=O)C1=C(C)[C@@H](O)[C@@H](C)[C@@H](O1)c2c(OC)c(OC)c(C)c(OC)c2OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K12 compound treatment 292316.0 -339000.0 -2.48 289022.0 -317000.0 -2.41 -3.4562 -0.9999 3132129 CMLD2_000205 C[C@H]1OC=C2[C@H](OC(=O)C)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5OC(C)[C@@H]([C@H]14)C6=C5[C@H](O)[C@H]7O[C@H]7C6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K13 compound treatment 677128.0 45500.0 0.33 625526.0 19800.0 0.15 0.3413 0.9355 3011362 CMLD2_000206 CO[C@H]1C[C@@H]2C[C@H](O)CC(CC(=O)O[C@H](C[C@@H]3CC[C@H](C)[C@@H](C1)O3)/C=C/CC(C)C)O2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K14 compound treatment 607687.0 -24000.0 -0.18 573440.0 -32300.0 -0.25 -0.2976 -0.9864 3011258 CMLD2_000207 CON(C)C(=O)c1nnc2c3ccccc3n(c2n1)S(=O)(=O)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K15 mock treatment 706560.0 74900.0 0.55 603610.0 -2150.0 -0.02 0.3758 0.6858 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K16 mock treatment 654620.0 23000.0 0.17 676217.0 70500.0 0.54 0.4972 0.8863 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K17 compound treatment 157587.0 -474000.0 -3.47 204866.0 -401000.0 -3.05 -4.605 -0.9979 3132248 CMLD2_000208 CCN1C(=O)[C@H]2CC=C3[C@H]([C@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C53OCCCO5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K18 compound treatment 607269.0 -24400.0 -0.18 579049.0 -26700.0 -0.2 -0.2696 -0.9979 3011363 CMLD2_000209 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K19 compound treatment 572833.0 -58800.0 -0.43 580098.0 -25700.0 -0.19 -0.442 -0.9359 3132249 CMLD2_000210 C[C@@H]1CC[C@@H]2N(CC(COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K20 compound treatment 715736.0 84100.0 0.61 636033.0 30300.0 0.23 0.5974 0.91 3011399 CMLD2_000211 CCCCc1nc2CCN(CCC(C)C)Cc2c3CO[C@@H](C)Cc13 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K21 compound treatment 689492.0 57800.0 0.42 603355.0 -2400.0 -0.02 0.2861 0.676 3132250 CMLD2_000212 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K22 compound treatment 700185.0 68500.0 0.5 582474.0 -23300.0 -0.18 0.2293 0.4314 3011400 CMLD2_000213 C[C@@H]1CC[C@H](N[C@H]1c2ccc(cc2)c3ccco3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K23 mock treatment 628131.0 -3530.0 -0.03 579478.0 -26300.0 -0.2 -0.1594 -0.792 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 K24 mock treatment 604358.0 -27300.0 -0.2 547203.0 -58600.0 -0.44 -0.4557 -0.9347 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L01 compound treatment 654453.0 22800.0 0.17 646204.0 40400.0 0.31 0.3351 0.9587 3132251 CMLD2_000214 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L02 compound treatment 630818.0 -845.0 -0.01 697453.0 91700.0 0.7 0.4882 0.7008 3132252 CMLD2_000215 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L03 compound treatment 561451.0 -70200.0 -0.51 630418.0 24700.0 0.19 -0.2306 -0.4219 3011402 CMLD2_000216 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3ccc4OCOc4c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L04 compound treatment 543155.0 -88500.0 -0.65 609088.0 3330.0 0.03 -0.4398 -0.6789 3132253 CMLD2_000217 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L05 compound treatment 678451.0 46800.0 0.34 690298.0 84500.0 0.64 0.6961 0.9565 3132254 CMLD2_000218 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L06 compound treatment 560611.0 -71100.0 -0.52 636252.0 30500.0 0.23 -0.2036 -0.3579 3011403 CMLD2_000219 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L07 mock treatment 674585.0 42900.0 0.31 730477.0 125000.0 0.95 0.8919 0.8936 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L08 mock treatment 672805.0 41100.0 0.3 619524.0 13800.0 0.1 0.2867 0.9001 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L09 compound treatment 667539.0 35900.0 0.26 639342.0 33600.0 0.26 0.3659 0.9999 3132255 CMLD2_000220 C/C=C/C1=C(CO)[C@H](O)[C@H]2O[C@H]2[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L10 compound treatment 621225.0 -10400.0 -0.08 643911.0 38200.0 0.29 0.151 0.5037 3132256 CMLD2_000221 COc1ccc(cc1)c2ccc3N(CC(O)CN4CCCc5nc(C)c(C)cc45)CCCc3n2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L11 compound treatment 614942.0 -16700.0 -0.12 627567.0 21800.0 0.17 0.0307 0.1491 3011404 CMLD2_000222 CCOC(=O)C1=NO[C@]2(C1)C=C(Br)C3(OCCCO3)[C@H]4O[C@H]42 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L12 compound treatment 614863.0 -16800.0 -0.12 660577.0 54800.0 0.42 0.2076 0.4781 3011405 CMLD2_000223 OC(CCc1ccccc1)C2=CCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L13 compound treatment 527827.0 -104000.0 -0.76 663137.0 57400.0 0.44 -0.2287 -0.2612 3132257 CMLD2_000224 OC(CCc1ccccc1)C23OC3CCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L14 compound treatment 602880.0 -28800.0 -0.21 607730.0 1970.0 0.01 -0.1382 -0.6551 3132258 CMLD2_000225 CCCNC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L15 mock treatment 694982.0 63300.0 0.46 567150.0 -38600.0 -0.29 0.1201 0.219 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L16 mock treatment 592965.0 -38700.0 -0.28 709585.0 104000.0 0.79 0.3576 0.4268 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L17 compound treatment 592473.0 -39200.0 -0.29 679671.0 73900.0 0.56 0.1944 0.3084 3011407 CMLD2_000226 C[C@H]1CC[C@@H]2N([C@@H]1c3ccccc3)C(=O)[C@@H](Cc4ccccc4)NC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L18 compound treatment 583027.0 -48600.0 -0.36 627309.0 21600.0 0.16 -0.1357 -0.3466 3132259 CMLD2_000227 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L19 compound treatment 694904.0 63200.0 0.46 578728.0 -27000.0 -0.21 0.1818 0.3594 3132260 CMLD2_000228 C[C@@H]1CC[C@@H]2N(CC(CN3C(=O)c4ccccc4C3=O)OC2=O)[C@H]1c5ccc(Br)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L20 compound treatment 744375.0 113000.0 0.82 621132.0 15400.0 0.12 0.6654 0.7993 3011408 CMLD2_000229 CC(C)CCN1CCc2nc(COc3ccccc3)c4C[C@H](C)OCc4c2C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L21 compound treatment 702963.0 71300.0 0.52 612999.0 7240.0 0.06 0.4076 0.7774 3132261 CMLD2_000230 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L22 compound treatment 747803.0 116000.0 0.85 638674.0 32900.0 0.25 0.7774 0.878 3011409 CMLD2_000231 C[C@H]1CC[C@H](N[C@@H]1c2ccc(C#CCN(C)C)cc2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L23 mock treatment 692215.0 60600.0 0.44 621247.0 15500.0 0.12 0.3963 0.865 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 L24 mock treatment 689408.0 57700.0 0.42 532828.0 -72900.0 -0.55 -0.0931 -0.1337 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M01 compound treatment 411449.0 -220000.0 -1.61 439345.0 -166000.0 -1.26 -2.0327 -0.9928 3132262 CMLD2_000232 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc4ccccc34)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M02 compound treatment 664895.0 33200.0 0.24 686665.0 80900.0 0.61 0.6065 0.9176 3132263 CMLD2_000233 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M03 compound treatment 474822.0 -157000.0 -1.15 572240.0 -33500.0 -0.25 -0.9911 -0.8435 3011410 CMLD2_000234 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC3CCCCC3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M04 compound treatment 649673.0 18000.0 0.13 656885.0 51100.0 0.39 0.3678 0.8967 3132264 CMLD2_000235 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCC(C)C)O3)O2)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M05 compound treatment 488408.0 -143000.0 -1.05 562643.0 -43100.0 -0.33 -0.9724 -0.8859 3132265 CMLD2_000236 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCC(c3ccccc3)c4ccccc4)O2)O1)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M06 compound treatment 654770.0 23100.0 0.17 640839.0 35100.0 0.27 0.3079 0.9758 3011411 CMLD2_000237 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccccc3OC)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M07 compound treatment 546484.0 -85200.0 -0.62 647679.0 41900.0 0.32 -0.2153 -0.3077 3132266 CMLD2_000238 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccncc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M08 compound treatment 693976.0 62300.0 0.46 635763.0 30000.0 0.23 0.4834 0.9487 3011412 CMLD2_000239 CC(C)[C@H](NC(=O)OC(C)(C)C)[C@@H](O)CC(=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M09 mock treatment 614134.0 -17500.0 -0.13 615303.0 9550.0 0.07 -0.0394 -0.2672 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M10 mock treatment 707998.0 76300.0 0.56 707218.0 101000.0 0.77 0.9398 0.9875 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M11 compound treatment 663905.0 32200.0 0.24 573222.0 -32500.0 -0.25 -0.008 -0.0235 3132389 CMLD2_000240 COC(=O)C/C=C/[C@@H](C)[C@H]1O[C@H](CO)[C@@H](O)C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M12 compound treatment 559400.0 -72300.0 -0.53 654194.0 48400.0 0.37 -0.1135 -0.1762 3011413 CMLD2_000241 O=C1CCCC(C1)C2=CCCCC2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M13 mock treatment 697086.0 65400.0 0.48 590835.0 -14900.0 -0.11 0.2582 0.525 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M14 mock treatment 666140.0 34500.0 0.25 583577.0 -22200.0 -0.17 0.0591 0.195 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M15 compound treatment 790222.0 159000.0 1.16 755197.0 149000.0 1.14 1.6227 0.9999 3132390 CMLD2_000242 Cc1cc2N(CC(O)CN3CCCc4nc(ccc34)c5ccc(Br)cc5)CCCCc2nc1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M16 compound treatment 619745.0 -11900.0 -0.09 688116.0 82400.0 0.63 0.3808 0.6028 3011415 CMLD2_000243 CCO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M17 mock treatment 680278.0 48600.0 0.36 616547.0 10800.0 0.08 0.3094 0.8479 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M18 compound treatment 711792.0 80100.0 0.59 622352.0 16600.0 0.13 0.5035 0.84 3132391 CMLD2_000244 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#CCC2CCCCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M19 compound treatment 641335.0 9670.0 0.07 699892.0 94100.0 0.72 0.5557 0.7733 3132392 CMLD2_000245 C[C@@H]1CC[C@@H]2N(CC(Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M20 compound treatment 679876.0 48200.0 0.35 641799.0 36000.0 0.27 0.4429 0.9922 3011466 CMLD2_000246 COc1ccc(cc1)c2nc3CCN(CCC(C)C)Cc3c4CO[C@@H](C)Cc24 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M21 compound treatment 750104.0 118000.0 0.87 536511.0 -69200.0 -0.53 0.2405 0.2373 3132393 CMLD2_000247 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCOC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M22 compound treatment 672065.0 40400.0 0.3 688226.0 82500.0 0.63 0.6519 0.9412 3011467 CMLD2_000248 C[C@H]1CC[C@H](N[C@@H]1c2cccc(c2)N3CCCC3=O)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M23 compound treatment 623915.0 -7750.0 -0.06 619308.0 13600.0 0.1 0.0327 0.2785 3132394 CMLD2_000249 C[C@@H]1CC[C@@H]2N([C@H]1c3ccc(Br)cc3)C(=O)[C@@H]4CCCN4C2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 M24 compound treatment 631600.0 -62.9 0.0 587506.0 -18200.0 -0.14 -0.0984 -0.7094 3132261 CMLD2_000250 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](CCCC4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N01 compound treatment 607097.0 -24600.0 -0.18 618108.0 12400.0 0.09 -0.0607 -0.2994 3132395 CMLD2_000251 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N02 compound treatment 565978.0 -65700.0 -0.48 703320.0 97600.0 0.74 0.1844 0.2088 3132396 CMLD2_000252 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOc4ccccc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N03 compound treatment 549808.0 -81900.0 -0.6 664767.0 59000.0 0.45 -0.1063 -0.1421 3011471 CMLD2_000253 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCCN3CCCC3=O)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N04 compound treatment 507059.0 -125000.0 -0.91 543101.0 -62700.0 -0.48 -0.9809 -0.9541 3132397 CMLD2_000254 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCOC)O3)O2)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N05 compound treatment 739564.0 108000.0 0.79 622780.0 17000.0 0.13 0.6494 0.8122 3011472 CMLD2_000255 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCc3ccc(Cl)cc3)O2)O1)OC(=O)NCCc4ccc(F)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N06 compound treatment 716327.0 84700.0 0.62 735781.0 130000.0 0.99 1.1363 0.9747 3132398 CMLD2_000256 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4cccc(c4)C(F)(F)F)O3)O2)OC(=O)NCc5cccc6ccccc56 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N07 compound treatment 687485.0 55800.0 0.41 697170.0 91400.0 0.69 0.7797 0.9679 3132399 CMLD2_000257 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCc4ccc5OCOc5c4)O3)O2)OC(=O)NCc6cccc7ccccc67 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N08 compound treatment 551289.0 -80400.0 -0.59 630278.0 24500.0 0.19 -0.2839 -0.4604 3011473 CMLD2_000258 Cc1ccc(cc1)S(=O)(=O)n2c3ccccc3c4nnc(nc24)C(=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N09 mock treatment 755546.0 124000.0 0.91 660866.0 55100.0 0.42 0.9367 0.9385 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N10 mock treatment 571984.0 -59700.0 -0.44 711821.0 106000.0 0.81 0.2611 0.285 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N11 compound treatment 714884.0 83200.0 0.61 677685.0 71900.0 0.55 0.8167 0.9986 3011475 CMLD2_000259 BrC1=CC(=C)[C@@H]2O[C@@H]2C31OCCCO3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N12 compound treatment 613570.0 -18100.0 -0.13 631133.0 25400.0 0.19 0.0428 0.1829 3132400 CMLD2_000260 CCCCOC(OCCCC)C(O)CSc1ccc2ccccc2c1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N13 mock treatment 723616.0 92000.0 0.67 591462.0 -14300.0 -0.11 0.3987 0.5853 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N14 mock treatment 646184.0 14500.0 0.11 654962.0 49200.0 0.37 0.3394 0.8734 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N15 compound treatment 489620.0 -142000.0 -1.04 511651.0 -94100.0 -0.71 -1.24 -0.9834 3011477 CMLD2_000261 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N16 compound treatment 830506.0 199000.0 1.45 722570.0 117000.0 0.89 1.6557 0.9719 3132401 CMLD2_000262 CO[C@@H](C(C)C)[C@@H](C)C1OC1CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N17 compound treatment 406676.0 -225000.0 -1.65 406775.0 -199000.0 -1.51 -2.2323 -0.9991 4845 CMLD2_000263 COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(O[C@]2([C@@H]1c4ccccc4)c5ccc(OC)cc5)cc(OC)cc3OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N18 compound treatment 791310.0 160000.0 1.17 624852.0 19100.0 0.15 0.9281 0.7889 3011479 CMLD2_000264 CCCCC#C[C@H]1O[C@H](COC(=O)OCC)[C@@H](Oc2cc(OC)c(OC)c(OC)c2)C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N19 compound treatment 769505.0 138000.0 1.01 538113.0 -67600.0 -0.51 0.3494 0.3088 3132403 CMLD2_000265 C[C@H]1CC[C@@H]2N(CC(COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N20 compound treatment 851900.0 220000.0 1.61 629837.0 24100.0 0.18 1.2682 0.7824 3011480 CMLD2_000266 C[C@H]1Cc2c(nc3CCN(CCOc4ccccc4)Cc3c2CO1)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N21 compound treatment 715712.0 84000.0 0.61 565301.0 -40500.0 -0.31 0.2173 0.3162 3132404 CMLD2_000267 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N22 compound treatment 661034.0 29400.0 0.21 560393.0 -45400.0 -0.34 -0.0918 -0.2261 3011481 CMLD2_000268 C[C@@H]1CC[C@H](N[C@H]1c2ccc(NC(=O)C)cc2)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N23 compound treatment 727746.0 96100.0 0.7 596069.0 -9690.0 -0.07 0.4448 0.6296 3132405 CMLD2_000269 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@H](C(C)C)N(C)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 N24 compound treatment 592717.0 -38900.0 -0.28 612703.0 6950.0 0.05 -0.1641 -0.5664 3131577 CMLD2_000270 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@@H]5[C@H]3C(=O)N(C)C5=O)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O01 compound treatment 669287.0 37600.0 0.28 651774.0 46000.0 0.35 0.4418 0.993 3132406 CMLD2_000271 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOC)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O02 compound treatment 529395.0 -102000.0 -0.75 604129.0 -1630.0 -0.01 -0.5376 -0.7187 3132407 CMLD2_000272 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC(c4ccccc4)c5ccccc5)O3)O2)OC(=O)NCc6ccc7OCOc7c6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O03 compound treatment 672039.0 40400.0 0.3 670722.0 65000.0 0.49 0.5578 0.9698 3011482 CMLD2_000273 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O04 compound treatment 757008.0 125000.0 0.92 652770.0 47000.0 0.36 0.9007 0.9156 3132527 CMLD2_000274 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCC4CCCCC4)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O05 compound treatment 657943.0 26300.0 0.19 589367.0 -16400.0 -0.12 0.0479 0.209 3011483 CMLD2_000275 COCCNC(=O)OCC1CCCC2(CC(CC(CCC(=O)N[C@@H](C)C(=O)OC)O2)OC(=O)NCCc3ccc(F)cc3)O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O06 compound treatment 804707.0 173000.0 1.27 588106.0 -17600.0 -0.13 0.8 0.6287 3132528 CMLD2_000276 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O07 compound treatment 598679.0 -33000.0 -0.24 582775.0 -23000.0 -0.17 -0.294 -0.9874 3011485 CMLD2_000277 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O08 compound treatment 655492.0 23800.0 0.17 611762.0 6010.0 0.05 0.1555 0.8632 3132529 CMLD2_000278 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O09 compound treatment 682436.0 50800.0 0.37 710414.0 105000.0 0.8 0.8248 0.9399 3011486 CMLD2_000279 COC(=O)[C@H]1O[C@H]([C@H](C)[C@@H](O)[C@H]1C)c2c(OC)c(OC)c(C)c(OC)c2OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O10 compound treatment 188155.0 -444000.0 -3.24 177144.0 -429000.0 -3.26 -4.5958 -1.0 3132530 CMLD2_000280 OC(CCCCBr)C1=CCCCC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O11 mock treatment 550295.0 -81400.0 -0.6 620958.0 15200.0 0.12 -0.3391 -0.5594 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O12 mock treatment 671757.0 40100.0 0.29 608494.0 2740.0 0.02 0.222 0.7554 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O13 compound treatment 855115.0 223000.0 1.63 640583.0 34800.0 0.26 1.3426 0.811 3132531 CMLD2_000281 COC(=O)C/C=C/[C@H](C)[C@@H](OCc1ccccc1Br)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O14 compound treatment 131176.0 -500000.0 -3.66 122720.0 -483000.0 -3.67 -5.1828 -1.0 3011535 CMLD2_000282 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O15 compound treatment 568984.0 -62700.0 -0.46 497101.0 -109000.0 -0.83 -0.9078 -0.9615 3132532 CMLD2_000283 Nc1ccccc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O16 compound treatment 656427.0 24800.0 0.18 667687.0 61900.0 0.47 0.4607 0.9139 3131858 CMLD2_000284 COC(=O)C/C=C/[C@@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O17 mock treatment 684718.0 53100.0 0.39 641130.0 35400.0 0.27 0.4644 0.9839 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O18 compound treatment 675608.0 43900.0 0.32 648466.0 42700.0 0.32 0.4567 1.0 3011536 CMLD2_000285 OC[C@H]1O[C@@H](C=C[C@@H]1O)C#Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O19 compound treatment 681543.0 49900.0 0.36 673231.0 67500.0 0.51 0.6204 0.9861 3132533 CMLD2_000286 C[C@H]1CC[C@@H]2N(C[C@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O20 compound treatment 796099.0 164000.0 1.2 620624.0 14900.0 0.11 0.9302 0.7701 3011537 CMLD2_000287 C[C@H]1Cc2c(COc3ccccc3)nc4CCN(CCOc5ccccc5)Cc4c2CO1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O21 compound treatment 708153.0 76500.0 0.56 709693.0 104000.0 0.79 0.9539 0.9857 3132534 CMLD2_000288 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O22 compound treatment 694785.0 63100.0 0.46 561391.0 -44400.0 -0.34 0.0881 0.1541 3011538 CMLD2_000289 C[C@@H]1CC[C@H](N[C@H]1c2cccc(c2)N3CCOCC3)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O23 compound treatment 737358.0 106000.0 0.77 603376.0 -2380.0 -0.02 0.5338 0.6904 3132535 CMLD2_000290 CCN1C(=C([C@H](N2C(=O)[C@@](O)([C@H](C(=C12)C(=O)c3ccccc3)c4ccccc4)C(=O)OC)c5ccccc5)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 O24 compound treatment 620370.0 -11300.0 -0.08 593214.0 -12500.0 -0.1 -0.1258 -0.9975 3132250 CMLD2_000291 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C4=O)c5ccccc5)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P01 compound treatment 648498.0 16800.0 0.12 647715.0 42000.0 0.32 0.3125 0.9144 3132536 CMLD2_000292 CCOC(=O)[C@H](CC(C)C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCc3cccc4ccccc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P02 compound treatment 682596.0 50900.0 0.37 672435.0 66700.0 0.51 0.6216 0.9886 3132537 CMLD2_000293 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCc4ccc(Cl)cc4)O3)O2)OC(=O)NCc5ccc6OCOc6c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P03 compound treatment 724465.0 92800.0 0.68 655666.0 49900.0 0.38 0.748 0.9622 3011540 CMLD2_000294 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCOc3ccccc3)O2)O1)OC(=O)NCc4ccc5OCOc5c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P04 compound treatment 696839.0 65200.0 0.48 623074.0 17300.0 0.13 0.4301 0.8698 3132538 CMLD2_000295 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)CCC2CC(CC3(CCCC(COC(=O)NCCCN4CCCC4=O)O3)O2)OC(=O)NCCc5ccc(F)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P05 compound treatment 564967.0 -66700.0 -0.49 518471.0 -87300.0 -0.66 -0.8138 -0.9886 3011541 CMLD2_000296 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCCC(C)C)O2)O1)OC(=O)NCCc3ccc(F)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P06 compound treatment 487285.0 -144000.0 -1.06 573790.0 -32000.0 -0.24 -0.9183 -0.8476 3132539 CMLD2_000297 COC(=O)[C@H](C)NC(=O)CCC1CC(CC2(CCCC(COC(=O)NCc3cccc(c3)C(F)(F)F)O2)O1)OC(=O)NCc4cccc5ccccc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P07 compound treatment 657814.0 26200.0 0.19 725063.0 119000.0 0.91 0.7761 0.8379 3011542 CMLD2_000298 CCN(CC)CC(O)CN1CCCCc2nc(C)c(C)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P08 compound treatment 744459.0 113000.0 0.82 675680.0 69900.0 0.53 0.9589 0.9773 3131847 CMLD2_000299 C[C@@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P09 compound treatment 687173.0 55500.0 0.41 563628.0 -42100.0 -0.32 0.0608 0.1175 3132540 CMLD2_000300 C[C@H]1OC=C2[C@@H](O)[C@H]3O[C@H]3C(=O)[C@@]42[C@H]5O[C@H](C)[C@@H]([C@H]14)C6=C5[C@@H](O)[C@H]7O[C@H]7C6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P10 compound treatment 435333.0 -196000.0 -1.44 385820.0 -220000.0 -1.67 -2.1967 -0.9972 3011543 CMLD2_000301 COCOc1ccc(Br)cc1C(=O)/C=C/c2ccc3OCOc3c2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P11 mock treatment 693276.0 61600.0 0.45 548894.0 -56900.0 -0.43 0.0132 0.0211 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P12 mock treatment 631133.0 -530.0 0.0 584550.0 -21200.0 -0.16 -0.1167 -0.7239 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P13 compound treatment 753740.0 122000.0 0.89 594026.0 -11700.0 -0.09 0.5683 0.6334 3132541 CMLD2_000302 COC(OC)[C@@H](C)[C@H](OC)[C@@H](C)[C@H](OC)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P14 compound treatment 752513.0 121000.0 0.88 596907.0 -8850.0 -0.07 0.5774 0.6514 3011544 CMLD2_000303 CC(C)c1ccc(C)n1C(=O)OC(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P15 compound treatment 619234.0 -12400.0 -0.09 605515.0 -241.0 0.0 -0.0656 -0.7212 3011545 CMLD2_000304 Brc1ccc(cc1)[C@@H]2OC(=O)C[C@@H]2c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P16 compound treatment 711687.0 80000.0 0.59 522616.0 -83100.0 -0.63 -0.0328 -0.0381 3132542 CMLD2_000305 COC(=O)[C@H]1[C@@H](C(=O)[C@]2(O)c3ccccc3O[C@@]12c4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P17 mock treatment 703330.0 71700.0 0.52 577265.0 -28500.0 -0.22 0.2176 0.3837 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P18 compound treatment 788397.0 157000.0 1.15 622137.0 16400.0 0.12 0.8985 0.7793 3132543 CMLD2_000306 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P19 compound treatment 715929.0 84300.0 0.62 567271.0 -38500.0 -0.29 0.229 0.3358 3011546 CMLD2_000307 C[C@@H]1CCC2N(C[C@H](O)CN(Cc3ccccc3)C2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P20 compound treatment 758961.0 127000.0 0.93 610012.0 4260.0 0.03 0.6811 0.7312 3132544 CMLD2_000308 CCCCc1nc2CCN(CCOc3ccccc3)Cc2c4CO[C@@H](C)Cc14 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P21 compound treatment 759184.0 128000.0 0.93 585451.0 -20300.0 -0.15 0.5504 0.5822 3131978 CMLD2_000309 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C(C[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c4ccccc4)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P22 compound treatment 752740.0 121000.0 0.89 611045.0 5290.0 0.04 0.6545 0.7384 3011547 CMLD2_000310 COCC#Cc1ccc(cc1)[C@@H]2N[C@@H](CC[C@H]2C)C(=O)O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P23 compound treatment 819452.0 188000.0 1.37 566720.0 -39000.0 -0.3 0.7614 0.5419 3132545 CMLD2_000311 COc1cccc(c1)[C@@H]2[C@@H](C)CC[C@@H]3N2C(=O)[C@@H]4CC[C@H](C)[C@H](N4C3=O)c5cccc(OC)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2109 P24 compound treatment 672967.0 41300.0 0.3 633790.0 28000.0 0.21 0.3642 0.9854 3132534 CMLD2_000312 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A01 compound treatment 416460.0 -142000.0 -1.04 557033.0 -44900.0 -0.34 -0.9768 -0.8922 3132546 CMLD2_000313 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A02 compound treatment 419973.0 -139000.0 -1.01 563262.0 -38700.0 -0.29 -0.9251 -0.8758 3011548 CMLD2_000314 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A03 compound treatment 513624.0 -45100.0 -0.33 559027.0 -42900.0 -0.33 -0.4636 -1.0 3130471 CMLD2_000315 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A04 compound treatment 511525.0 -47200.0 -0.35 529278.0 -72600.0 -0.55 -0.6343 -0.9745 3130472 CMLD2_000316 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A05 compound treatment 464376.0 -94300.0 -0.69 544705.0 -57200.0 -0.43 -0.7952 -0.9752 3011549 CMLD2_000317 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A06 compound treatment 548009.0 -10700.0 -0.08 533508.0 -68400.0 -0.52 -0.4229 -0.8046 3011597 CMLD2_000318 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A07 compound treatment 562608.0 3890.0 0.03 578374.0 -23500.0 -0.18 -0.1064 -0.5873 3130473 CMLD2_000319 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A08 compound treatment 472697.0 -86000.0 -0.63 569684.0 -32200.0 -0.24 -0.618 -0.9154 3010878 CMLD2_000320 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A09 compound treatment 466277.0 -92400.0 -0.68 593319.0 -8600.0 -0.07 -0.5242 -0.7718 3130474 CMLD2_000321 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A10 compound treatment 488448.0 -70300.0 -0.51 573476.0 -28400.0 -0.22 -0.5162 -0.9259 3010879 CMLD2_000322 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A11 compound treatment 547878.0 -10800.0 -0.08 549579.0 -52300.0 -0.4 -0.3372 -0.8317 3130475 CMLD2_000323 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A12 compound treatment 577030.0 18300.0 0.13 619036.0 17100.0 0.13 0.1866 0.9999 3130476 CMLD2_000324 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A13 mock treatment 538363.0 -20400.0 -0.15 644682.0 42800.0 0.32 0.1245 0.3483 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A14 mock treatment 550782.0 -7940.0 -0.06 636144.0 34200.0 0.26 0.1428 0.5361 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A15 compound treatment 554965.0 -3750.0 -0.03 591974.0 -9940.0 -0.08 -0.0728 -0.9061 3010880 CMLD2_000325 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A16 compound treatment 565507.0 6790.0 0.05 583791.0 -18100.0 -0.14 -0.0623 -0.4254 3130477 CMLD2_000326 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A17 compound treatment 162289.0 -396000.0 -2.9 167717.0 -434000.0 -3.3 -4.3824 -0.9979 3010881 CMLD2_000327 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A18 compound treatment 555843.0 -2880.0 -0.02 611530.0 9610.0 0.07 0.0368 0.4838 3130478 CMLD2_000328 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A19 compound treatment 549804.0 -8910.0 -0.07 624742.0 22800.0 0.17 0.0765 0.413 3130479 CMLD2_000329 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A20 compound treatment 544390.0 -14300.0 -0.1 634365.0 32400.0 0.25 0.1002 0.3741 3010882 CMLD2_000330 C[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H](C)NC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A21 compound treatment 599780.0 41100.0 0.3 655278.0 53400.0 0.41 0.499 0.9891 3130480 CMLD2_000331 C[C@H]/1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C\C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A22 compound treatment 582382.0 23700.0 0.17 635889.0 34000.0 0.26 0.3048 0.9811 3010883 CMLD2_000332 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc3ccccc3)\C=C\[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A23 compound treatment 641814.0 83100.0 0.61 671892.0 70000.0 0.53 0.8056 0.9978 3130481 CMLD2_000333 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 A24 compound treatment 538300.0 -20400.0 -0.15 651017.0 49100.0 0.37 0.1582 0.3936 3130482 CMLD2_000334 C[C@@H]1/C=C/CC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2O)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B01 compound treatment 495357.0 -63400.0 -0.46 633999.0 32100.0 0.24 -0.1553 -0.2967 3010884 CMLD2_000335 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B02 compound treatment 460940.0 -97800.0 -0.72 508325.0 -93600.0 -0.71 -1.0084 -1.0 3130483 CMLD2_000336 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B03 compound treatment 538647.0 -20100.0 -0.15 555406.0 -46500.0 -0.35 -0.3536 -0.9243 3130484 CMLD2_000337 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B04 compound treatment 477132.0 -81600.0 -0.6 504885.0 -97000.0 -0.74 -0.9431 -0.9945 3010885 CMLD2_000338 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B05 compound treatment 400974.0 -158000.0 -1.15 461635.0 -140000.0 -1.07 -1.5693 -0.9992 3130485 CMLD2_000339 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B06 compound treatment 478930.0 -79800.0 -0.58 516032.0 -85900.0 -0.65 -0.874 -0.9984 3010886 CMLD2_000340 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B07 compound treatment 509276.0 -49400.0 -0.36 614631.0 12700.0 0.1 -0.1874 -0.5007 3130486 CMLD2_000341 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B08 compound treatment 449785.0 -109000.0 -0.8 589957.0 -12000.0 -0.09 -0.6276 -0.7827 3130487 CMLD2_000342 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B09 compound treatment 527007.0 -31700.0 -0.23 554598.0 -47300.0 -0.36 -0.4182 -0.9775 3010887 CMLD2_000343 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B10 compound treatment 344937.0 -214000.0 -1.56 405711.0 -196000.0 -1.49 -2.1595 -0.9997 3130488 CMLD2_000344 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B11 compound treatment 547027.0 -11700.0 -0.09 635627.0 33700.0 0.26 0.1206 0.4468 3010888 CMLD2_000345 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B12 compound treatment 580410.0 21700.0 0.16 638670.0 36800.0 0.28 0.3096 0.9641 3130489 CMLD2_000346 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B13 mock treatment 591945.0 33200.0 0.24 638999.0 37100.0 0.28 0.371 0.9973 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B14 mock treatment 607387.0 48700.0 0.36 670071.0 68200.0 0.52 0.6178 0.9833 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B15 compound treatment 229175.0 -330000.0 -2.41 218755.0 -383000.0 -2.91 -3.7624 -0.9956 3130616 CMLD2_000347 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCc6ccccc6)n3c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B16 compound treatment 590867.0 32100.0 0.24 649249.0 47300.0 0.36 0.4205 0.9788 3010889 CMLD2_000348 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B17 compound treatment 425055.0 -134000.0 -0.98 557706.0 -44200.0 -0.34 -0.9287 -0.8985 3130617 CMLD2_000349 CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B18 compound treatment 503737.0 -55000.0 -0.4 702802.0 101000.0 0.77 0.2576 0.2976 3010924 CMLD2_000350 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B19 compound treatment 555601.0 -3120.0 -0.02 610701.0 8780.0 0.07 0.0311 0.4405 3130618 CMLD2_000351 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B20 compound treatment 457843.0 -101000.0 -0.74 616779.0 14900.0 0.11 -0.4418 -0.592 3130619 CMLD2_000352 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B21 compound treatment 524285.0 -34400.0 -0.25 700435.0 98500.0 0.75 0.3511 0.4447 3010926 CMLD2_000353 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B22 compound treatment 559374.0 655.0 0.0 575692.0 -26200.0 -0.2 -0.1375 -0.6899 3130620 CMLD2_000354 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B23 compound treatment 637346.0 78600.0 0.58 709468.0 108000.0 0.82 0.9843 0.9852 3130621 CMLD2_000355 C[C@@H]/1COC(=O)N[C@@H](C)C(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 B24 compound treatment 514850.0 -43900.0 -0.32 607938.0 6020.0 0.05 -0.1945 -0.6002 3010928 CMLD2_000356 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H]3O[C@H](COC1=O)[C@@H](O)C=C3)[C@@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C01 compound treatment 459622.0 -99100.0 -0.72 528183.0 -73700.0 -0.56 -0.9085 -0.9919 3130622 CMLD2_000357 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C02 compound treatment 404793.0 -154000.0 -1.13 491490.0 -110000.0 -0.84 -1.3892 -0.9895 3130623 CMLD2_000358 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C03 compound treatment 464976.0 -93700.0 -0.69 492413.0 -110000.0 -0.83 -1.073 -0.9954 3010930 CMLD2_000359 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C04 compound treatment 528183.0 -30500.0 -0.22 494839.0 -107000.0 -0.81 -0.7331 -0.8691 3130624 CMLD2_000360 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C05 compound treatment 432526.0 -126000.0 -0.92 501316.0 -101000.0 -0.76 -1.193 -0.9956 3010931 CMLD2_000361 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C06 compound treatment 451416.0 -107000.0 -0.78 547047.0 -54900.0 -0.42 -0.8496 -0.9562 3130625 CMLD2_000362 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C07 compound treatment 541149.0 -17600.0 -0.13 599918.0 -2000.0 -0.02 -0.1016 -0.7853 3130626 CMLD2_000363 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C08 compound treatment 413936.0 -145000.0 -1.06 586970.0 -14900.0 -0.11 -0.829 -0.7785 3010932 CMLD2_000364 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C09 compound treatment 544621.0 -14100.0 -0.1 607550.0 5630.0 0.04 -0.0426 -0.3821 3130627 CMLD2_000365 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C10 compound treatment 525251.0 -33500.0 -0.24 606457.0 4540.0 0.03 -0.1487 -0.6016 3010933 CMLD2_000366 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C11 mock treatment 524335.0 -34400.0 -0.25 598816.0 -3100.0 -0.02 -0.1945 -0.77 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C12 mock treatment 470310.0 -88400.0 -0.65 599570.0 -2350.0 -0.02 -0.4698 -0.7263 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C13 compound treatment 592079.0 33400.0 0.24 555572.0 -46300.0 -0.35 -0.0764 -0.1785 3130628 CMLD2_000367 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C14 compound treatment 508756.0 -50000.0 -0.37 592693.0 -9230.0 -0.07 -0.3079 -0.8277 3010934 CMLD2_000368 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C15 mock treatment 603977.0 45300.0 0.33 674581.0 72700.0 0.55 0.6244 0.9701 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C16 mock treatment 620045.0 61300.0 0.45 648750.0 46800.0 0.36 0.5687 0.9934 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C17 compound treatment 594780.0 36100.0 0.26 599868.0 -2050.0 -0.02 0.1755 0.6642 3130629 CMLD2_000369 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C18 compound treatment 518606.0 -40100.0 -0.29 629199.0 27300.0 0.21 -0.0609 -0.1695 3130630 CMLD2_000370 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C19 compound treatment 577647.0 18900.0 0.14 644053.0 42100.0 0.32 0.3242 0.9297 3010935 CMLD2_000371 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C20 compound treatment 604017.0 45300.0 0.33 636790.0 34900.0 0.26 0.4216 0.9939 3130631 CMLD2_000372 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C21 compound treatment 559157.0 438.0 0.0 659877.0 58000.0 0.44 0.3136 0.7122 3010936 CMLD2_000373 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C22 compound treatment 592479.0 33800.0 0.25 603301.0 1380.0 0.01 0.182 0.7365 3130632 CMLD2_000374 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C23 compound treatment 582088.0 23400.0 0.17 530877.0 -71000.0 -0.54 -0.2608 -0.4606 3130633 CMLD2_000375 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 C24 compound treatment 563384.0 4670.0 0.03 608836.0 6920.0 0.05 0.0613 0.9781 3010937 CMLD2_000376 C[C@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D01 compound treatment 384177.0 -175000.0 -1.28 589512.0 -12400.0 -0.09 -0.9692 -0.7573 3130634 CMLD2_000377 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D02 compound treatment 457254.0 -101000.0 -0.74 542115.0 -59800.0 -0.45 -0.8459 -0.9723 3010938 CMLD2_000378 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D03 compound treatment 432314.0 -126000.0 -0.92 495815.0 -106000.0 -0.81 -1.2236 -0.9977 3130635 CMLD2_000379 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D04 compound treatment 458743.0 -100000.0 -0.73 466346.0 -136000.0 -1.03 -1.2452 -0.9859 3130759 CMLD2_000380 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D05 compound treatment 408005.0 -151000.0 -1.1 456004.0 -146000.0 -1.11 -1.5632 -1.0 3010939 CMLD2_000381 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D06 compound treatment 537465.0 -21300.0 -0.16 581128.0 -20800.0 -0.16 -0.2216 -1.0 3130760 CMLD2_000382 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D07 compound treatment 458297.0 -100000.0 -0.73 551345.0 -50600.0 -0.38 -0.791 -0.9543 3130761 CMLD2_000383 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D08 compound treatment 479067.0 -79700.0 -0.58 615151.0 13200.0 0.1 -0.3408 -0.5766 3130762 CMLD2_000384 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D09 compound treatment 487873.0 -70800.0 -0.52 628782.0 26900.0 0.2 -0.222 -0.3988 3010981 CMLD2_000385 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D10 compound treatment 480955.0 -77800.0 -0.57 640612.0 38700.0 0.29 -0.1943 -0.3035 3130763 CMLD2_000386 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D11 mock treatment 574325.0 15600.0 0.11 648533.0 46600.0 0.35 0.3311 0.8899 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D12 mock treatment 476536.0 -82200.0 -0.6 565785.0 -36100.0 -0.27 -0.6191 -0.937 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D13 compound treatment 555088.0 -3630.0 -0.03 660828.0 58900.0 0.45 0.2977 0.664 3130764 CMLD2_000387 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D14 compound treatment 478375.0 -80300.0 -0.59 642779.0 40900.0 0.31 -0.196 -0.2949 3010983 CMLD2_000388 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D15 mock treatment 538328.0 -20400.0 -0.15 662820.0 60900.0 0.46 0.2217 0.4561 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D16 mock treatment 489735.0 -69000.0 -0.5 631990.0 30100.0 0.23 -0.1952 -0.3525 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D17 compound treatment 489887.0 -68800.0 -0.5 671547.0 69600.0 0.53 0.0181 0.0248 3130765 CMLD2_000389 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D18 compound treatment 547113.0 -11600.0 -0.08 646161.0 44200.0 0.34 0.1776 0.5125 3010984 CMLD2_000390 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D19 compound treatment 563779.0 5060.0 0.04 714010.0 112000.0 0.85 0.6283 0.7371 3130766 CMLD2_000391 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D20 compound treatment 574137.0 15400.0 0.11 679210.0 77300.0 0.59 0.4949 0.8278 3010985 CMLD2_000392 CO[C@@H]1/C=C/CC(=O)N[C@@H](C)C(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D21 compound treatment 610548.0 51800.0 0.38 505871.0 -96000.0 -0.73 -0.2479 -0.3015 3130767 CMLD2_000393 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D22 compound treatment 549228.0 -9490.0 -0.07 683507.0 81600.0 0.62 0.3892 0.624 3130768 CMLD2_000394 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D23 compound treatment 560019.0 1300.0 0.01 663539.0 61600.0 0.47 0.3377 0.7213 3130619 CMLD2_000395 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 D24 compound treatment 546473.0 -12200.0 -0.09 624384.0 22500.0 0.17 0.0574 0.2976 3010986 CMLD2_000396 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E01 mock treatment 465392.0 -93300.0 -0.68 603248.0 1330.0 0.01 -0.4755 -0.6966 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E02 mock treatment 449057.0 -110000.0 -0.8 544347.0 -57600.0 -0.44 -0.8763 -0.9593 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E03 compound treatment 455113.0 -104000.0 -0.76 492384.0 -110000.0 -0.83 -1.1242 -0.9989 3130769 CMLD2_000397 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E04 compound treatment 528174.0 -30500.0 -0.22 542105.0 -59800.0 -0.45 -0.4793 -0.9465 3130770 CMLD2_000398 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E05 compound treatment 514367.0 -44400.0 -0.32 490905.0 -111000.0 -0.84 -0.8257 -0.9138 3010987 CMLD2_000399 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E06 compound treatment 546800.0 -11900.0 -0.09 472227.0 -130000.0 -0.99 -0.7583 -0.7667 3130771 CMLD2_000400 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E07 compound treatment 538359.0 -20400.0 -0.15 582793.0 -19100.0 -0.15 -0.208 -0.9999 3130772 CMLD2_000401 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E08 compound treatment 475552.0 -83200.0 -0.61 594410.0 -7510.0 -0.06 -0.4704 -0.77 3010988 CMLD2_000402 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E09 mock treatment 501253.0 -57500.0 -0.42 491059.0 -111000.0 -0.84 -0.8927 -0.9484 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E10 mock treatment 526957.0 -31800.0 -0.23 549211.0 -52700.0 -0.4 -0.4474 -0.9665 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E11 compound treatment 511561.0 -47200.0 -0.34 556794.0 -45100.0 -0.34 -0.4863 -1.0 3130773 CMLD2_000403 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E12 compound treatment 498659.0 -60100.0 -0.44 558562.0 -43400.0 -0.33 -0.5435 -0.9899 3010989 CMLD2_000404 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E13 compound treatment 573164.0 14400.0 0.11 472245.0 -130000.0 -0.99 -0.6219 -0.6277 3130774 CMLD2_000405 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E14 compound treatment 537861.0 -20900.0 -0.15 635962.0 34000.0 0.26 0.075 0.2498 3130775 CMLD2_000406 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E15 compound treatment 490905.0 -67800.0 -0.5 594854.0 -7060.0 -0.05 -0.3886 -0.7791 3010990 CMLD2_000407 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCC(C)C)n3c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E16 compound treatment 607232.0 48500.0 0.35 645241.0 43300.0 0.33 0.4836 0.9993 3130776 CMLD2_000408 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E17 mock treatment 598717.0 40000.0 0.29 627117.0 25200.0 0.19 0.3422 0.9789 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E18 mock treatment 554503.0 -4220.0 -0.03 631490.0 29600.0 0.22 0.1371 0.6044 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E19 compound treatment 598417.0 39700.0 0.29 626665.0 24700.0 0.19 0.3382 0.9779 3010991 CMLD2_000409 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E20 compound treatment 604959.0 46200.0 0.34 656168.0 54200.0 0.41 0.5305 0.9952 3130777 CMLD2_000410 C[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E21 compound treatment 615562.0 56800.0 0.42 632778.0 30900.0 0.23 0.4597 0.9633 3130778 CMLD2_000411 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E22 compound treatment 617414.0 58700.0 0.43 614914.0 13000.0 0.1 0.3733 0.8476 3010992 CMLD2_000412 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E23 compound treatment 559464.0 745.0 0.01 607361.0 5440.0 0.04 0.0331 0.7935 3130904 CMLD2_000413 CO[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C)NS(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 E24 compound treatment 565387.0 6670.0 0.05 579850.0 -22100.0 -0.17 -0.0841 -0.4815 3130905 CMLD2_000414 CO[C@@H]1COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F01 mock treatment 454489.0 -104000.0 -0.76 527947.0 -74000.0 -0.56 -0.9363 -0.9888 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F02 mock treatment 450249.0 -108000.0 -0.79 498661.0 -103000.0 -0.78 -1.1156 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F03 compound treatment 419954.0 -139000.0 -1.01 551807.0 -50100.0 -0.38 -0.9868 -0.9104 3010993 CMLD2_000415 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F04 compound treatment 466957.0 -91800.0 -0.67 582425.0 -19500.0 -0.15 -0.5792 -0.8429 3130906 CMLD2_000416 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F05 compound treatment 484947.0 -73800.0 -0.54 581277.0 -20600.0 -0.16 -0.4924 -0.8764 3130907 CMLD2_000417 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F06 compound treatment 437506.0 -121000.0 -0.89 481064.0 -121000.0 -0.92 -1.276 -0.9998 3011036 CMLD2_000418 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F07 compound treatment 558225.0 -494.0 0.0 510775.0 -91100.0 -0.69 -0.4922 -0.7108 3130908 CMLD2_000419 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F08 compound treatment 455062.0 -104000.0 -0.76 556550.0 -45400.0 -0.34 -0.7797 -0.9364 3130909 CMLD2_000420 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F09 mock treatment 410483.0 -148000.0 -1.08 612696.0 10800.0 0.08 -0.7087 -0.6518 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F10 mock treatment 390689.0 -168000.0 -1.23 555180.0 -46700.0 -0.36 -1.12 -0.8756 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F11 compound treatment 505097.0 -53600.0 -0.39 602611.0 692.0 0.01 -0.2736 -0.6976 3011038 CMLD2_000421 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F12 compound treatment 448483.0 -110000.0 -0.81 555048.0 -46900.0 -0.36 -0.8218 -0.9325 3130910 CMLD2_000422 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F13 compound treatment 616635.0 57900.0 0.42 486047.0 -116000.0 -0.88 -0.3229 -0.3306 3011039 CMLD2_000423 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F14 compound treatment 499207.0 -59500.0 -0.44 581477.0 -20400.0 -0.16 -0.4175 -0.9036 3130911 CMLD2_000424 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F15 compound treatment 446281.0 -112000.0 -0.82 435570.0 -166000.0 -1.26 -1.475 -0.9783 3130912 CMLD2_000425 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC\C=C(/C)\CCC=C(C)C)n3c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F16 compound treatment 594231.0 35500.0 0.26 587270.0 -14600.0 -0.11 0.105 0.3715 3011040 CMLD2_000426 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F17 mock treatment 630537.0 71800.0 0.53 633758.0 31800.0 0.24 0.5424 0.9381 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F18 mock treatment 585841.0 27100.0 0.2 665398.0 63500.0 0.48 0.4812 0.9229 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F19 compound treatment 562226.0 3510.0 0.03 651070.0 49200.0 0.37 0.2822 0.7539 3011041 CMLD2_000427 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F20 compound treatment 599293.0 40600.0 0.3 677689.0 75800.0 0.58 0.6168 0.9525 3130913 CMLD2_000428 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F21 compound treatment 558760.0 41.4 0.0 645646.0 43700.0 0.33 0.2351 0.7078 3130914 CMLD2_000429 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F22 compound treatment 496981.0 -61700.0 -0.45 635479.0 33600.0 0.25 -0.139 -0.268 3011043 CMLD2_000430 C[C@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC1=O)[C@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F23 compound treatment 520060.0 -38700.0 -0.28 639917.0 38000.0 0.29 0.0042 0.0104 3130915 CMLD2_000431 CO[C@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 F24 compound treatment 543552.0 -15200.0 -0.11 657218.0 55300.0 0.42 0.2186 0.5032 3011044 CMLD2_000432 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G01 compound treatment 466451.0 -92300.0 -0.67 418238.0 -184000.0 -1.4 -1.4638 -0.9444 3130916 CMLD2_000433 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G02 compound treatment 488997.0 -69700.0 -0.51 510717.0 -91200.0 -0.69 -0.8505 -0.9886 3130917 CMLD2_000434 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G03 mock treatment 396030.0 -163000.0 -1.19 526512.0 -75400.0 -0.57 -1.2464 -0.9439 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G04 mock treatment 445078.0 -114000.0 -0.83 469790.0 -132000.0 -1.0 -1.2974 -0.9956 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G05 compound treatment 526207.0 -32500.0 -0.24 522917.0 -79000.0 -0.6 -0.5925 -0.9178 3011046 CMLD2_000435 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G06 compound treatment 434925.0 -124000.0 -0.91 494804.0 -107000.0 -0.81 -1.2155 -0.9986 3130918 CMLD2_000436 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G07 compound treatment 516414.0 -42300.0 -0.31 534515.0 -67400.0 -0.51 -0.5808 -0.9709 3130919 CMLD2_000437 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G08 compound treatment 491989.0 -66700.0 -0.49 550056.0 -51900.0 -0.39 -0.6237 -0.9944 3011047 CMLD2_000438 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G09 compound treatment 508192.0 -50500.0 -0.37 483461.0 -118000.0 -0.9 -0.8976 -0.9227 3130920 CMLD2_000439 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G10 compound treatment 540121.0 -18600.0 -0.14 596817.0 -5100.0 -0.04 -0.1236 -0.8738 3011048 CMLD2_000440 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G11 compound treatment 504932.0 -53800.0 -0.39 580444.0 -21500.0 -0.16 -0.3935 -0.9241 3130921 CMLD2_000441 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G12 compound treatment 532044.0 -26700.0 -0.2 510928.0 -91000.0 -0.69 -0.6267 -0.8726 3131048 CMLD2_000442 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G13 compound treatment 497931.0 -60800.0 -0.44 448448.0 -153000.0 -1.17 -1.1387 -0.9126 3011049 CMLD2_000443 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G14 compound treatment 600154.0 41400.0 0.3 621986.0 20100.0 0.15 0.3221 0.9495 3131049 CMLD2_000444 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(CC)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G15 compound treatment 524151.0 -34600.0 -0.25 611265.0 9350.0 0.07 -0.1285 -0.4896 3011050 CMLD2_000445 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OCCCC#C)n3c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G16 compound treatment 155392.0 -403000.0 -2.95 158596.0 -443000.0 -3.37 -4.4671 -0.9978 3131050 CMLD2_000446 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G17 compound treatment 639747.0 81000.0 0.59 562716.0 -39200.0 -0.3 0.2084 0.3143 3131051 CMLD2_000447 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G18 compound treatment 520248.0 -38500.0 -0.28 652024.0 50100.0 0.38 0.0702 0.1483 3011052 CMLD2_000448 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G19 mock treatment 649644.0 90900.0 0.66 642031.0 40100.0 0.3 0.6857 0.9374 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G20 mock treatment 564870.0 6150.0 0.04 614751.0 12800.0 0.1 0.1007 0.9383 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G21 compound treatment 643876.0 85200.0 0.62 640051.0 38100.0 0.29 0.6452 0.9394 3131052 CMLD2_000449 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)NC(=O)C\C=C\[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G22 compound treatment 680060.0 121000.0 0.89 465124.0 -137000.0 -1.04 -0.1073 -0.0786 3011053 CMLD2_000450 C[C@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G23 compound treatment 630008.0 71300.0 0.52 500123.0 -102000.0 -0.77 -0.1782 -0.191 3131053 CMLD2_000451 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@@H]3CCCN3C1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 G24 compound treatment 526612.0 -32100.0 -0.23 641916.0 40000.0 0.3 0.0488 0.1272 3131054 CMLD2_000452 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H01 compound treatment 452575.0 -106000.0 -0.78 509111.0 -92800.0 -0.71 -1.0474 -0.9988 3011098 CMLD2_000453 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H02 compound treatment 482950.0 -75800.0 -0.55 498690.0 -103000.0 -0.78 -0.9463 -0.9855 3131055 CMLD2_000454 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H03 mock treatment 411708.0 -147000.0 -1.08 472874.0 -129000.0 -0.98 -1.4534 -0.9989 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H04 mock treatment 446128.0 -113000.0 -0.82 494840.0 -107000.0 -0.81 -1.1574 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H05 compound treatment 461702.0 -97000.0 -0.71 520944.0 -81000.0 -0.62 -0.9367 -0.9975 3131056 CMLD2_000455 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H06 compound treatment 461496.0 -97200.0 -0.71 477093.0 -125000.0 -0.95 -1.1733 -0.9899 3011099 CMLD2_000456 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H07 compound treatment 516755.0 -42000.0 -0.31 526545.0 -75400.0 -0.57 -0.6219 -0.9573 3131057 CMLD2_000457 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H08 compound treatment 465077.0 -93600.0 -0.68 512197.0 -89700.0 -0.68 -0.9662 -1.0 3011100 CMLD2_000458 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N([C@@H](C)c5ccccc5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H09 compound treatment 435112.0 -124000.0 -0.9 514202.0 -87700.0 -0.67 -1.1104 -0.9887 3131058 CMLD2_000459 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H10 compound treatment 471733.0 -87000.0 -0.64 559999.0 -41900.0 -0.32 -0.675 -0.9488 3131059 CMLD2_000460 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H11 compound treatment 470477.0 -88200.0 -0.65 542230.0 -59700.0 -0.45 -0.7769 -0.9851 3011101 CMLD2_000461 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H12 compound treatment 491019.0 -67700.0 -0.5 624717.0 22800.0 0.17 -0.2276 -0.434 3131060 CMLD2_000462 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H13 compound treatment 553168.0 -5550.0 -0.04 581392.0 -20500.0 -0.16 -0.139 -0.8624 3131061 CMLD2_000463 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H14 compound treatment 510484.0 -48200.0 -0.35 627596.0 25700.0 0.2 -0.1115 -0.2766 3011102 CMLD2_000464 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H15 compound treatment 517908.0 -40800.0 -0.3 570764.0 -31200.0 -0.24 -0.3784 -0.9934 3131062 CMLD2_000465 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]/4[C@H]([C@H](O)[C@@H]5O[C@@H]5\C4=N/OC[C@@H](O)COCc6ccco6)n3c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H16 compound treatment 564689.0 5970.0 0.04 608416.0 6500.0 0.05 0.0658 0.9981 3011103 CMLD2_000466 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H17 compound treatment 650550.0 91800.0 0.67 633497.0 31600.0 0.24 0.6445 0.9038 3131063 CMLD2_000467 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H18 compound treatment 574254.0 15500.0 0.11 569525.0 -32400.0 -0.25 -0.0937 -0.3456 3011104 CMLD2_000468 CCN1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H19 mock treatment 561366.0 2650.0 0.02 588837.0 -13100.0 -0.1 -0.0566 -0.5588 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H20 mock treatment 618980.0 60300.0 0.44 611968.0 10000.0 0.08 0.3656 0.8174 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H21 compound treatment 559574.0 855.0 0.01 637574.0 35700.0 0.27 0.196 0.7232 3131064 CMLD2_000469 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H22 compound treatment 625574.0 66900.0 0.49 547183.0 -54700.0 -0.42 0.0517 0.0805 3011105 CMLD2_000470 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H23 compound treatment 603988.0 45300.0 0.33 681522.0 79600.0 0.6 0.6617 0.9598 3131065 CMLD2_000471 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 H24 compound treatment 583841.0 25100.0 0.18 676463.0 74500.0 0.57 0.5303 0.8908 3131066 CMLD2_000472 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I01 compound treatment 499267.0 -59500.0 -0.43 573158.0 -28800.0 -0.22 -0.4619 -0.9493 3011106 CMLD2_000473 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I02 compound treatment 546485.0 -12200.0 -0.09 343731.0 -258000.0 -1.96 -1.4502 -0.7386 3131067 CMLD2_000474 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I03 compound treatment 473671.0 -85000.0 -0.62 515649.0 -86300.0 -0.66 -0.9032 -0.9997 3131183 CMLD2_000475 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I04 compound treatment 507947.0 -50800.0 -0.37 564347.0 -37600.0 -0.29 -0.4644 -0.9916 3011108 CMLD2_000476 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I05 mock treatment 538215.0 -20500.0 -0.15 535279.0 -66600.0 -0.51 -0.464 -0.8788 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I06 mock treatment 513017.0 -45700.0 -0.33 525886.0 -76000.0 -0.58 -0.6448 -0.9662 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I07 compound treatment 515483.0 -43200.0 -0.32 584888.0 -17000.0 -0.13 -0.3151 -0.9222 3131184 CMLD2_000477 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I08 compound treatment 462317.0 -96400.0 -0.7 607681.0 5760.0 0.04 -0.4676 -0.6619 3011109 CMLD2_000478 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I09 compound treatment 518911.0 -39800.0 -0.29 594065.0 -7850.0 -0.06 -0.248 -0.8347 3131185 CMLD2_000479 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I10 compound treatment 509486.0 -49200.0 -0.36 588946.0 -13000.0 -0.1 -0.3243 -0.8687 3131186 CMLD2_000480 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I11 compound treatment 555878.0 -2840.0 -0.02 550891.0 -51000.0 -0.39 -0.2888 -0.7439 3011110 CMLD2_000481 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I12 compound treatment 519784.0 -38900.0 -0.28 566564.0 -35400.0 -0.27 -0.3913 -0.9996 3131187 CMLD2_000482 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I13 compound treatment 635372.0 76700.0 0.56 610750.0 8830.0 0.07 0.4438 0.7861 3131188 CMLD2_000483 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I14 compound treatment 536844.0 -21900.0 -0.16 598681.0 -3240.0 -0.02 -0.1305 -0.8063 3011112 CMLD2_000484 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I15 compound treatment 583554.0 24800.0 0.18 636872.0 35000.0 0.27 0.3162 0.9828 3131189 CMLD2_000485 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCc5ccccc5)n2c1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I16 compound treatment 194403.0 -364000.0 -2.66 211786.0 -390000.0 -2.96 -3.9796 -0.9986 3011154 CMLD2_000486 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I17 compound treatment 628217.0 69500.0 0.51 547263.0 -54700.0 -0.42 0.0658 0.1002 3131190 CMLD2_000487 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I18 compound treatment 542897.0 -15800.0 -0.12 661134.0 59200.0 0.45 0.2363 0.5087 3010995 CMLD2_000488 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I19 compound treatment 503424.0 -55300.0 -0.4 543181.0 -58700.0 -0.45 -0.6015 -0.9988 3131191 CMLD2_000489 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I20 compound treatment 535166.0 -23600.0 -0.17 643109.0 41200.0 0.31 0.0995 0.2785 3131192 CMLD2_000490 C[C@H]/1COC(=O)C\C=C\[C@H](C)[C@H](COC(=O)C\C=C1)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I21 mock treatment 511069.0 -47600.0 -0.35 606012.0 4090.0 0.03 -0.2244 -0.6415 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I22 mock treatment 618106.0 59400.0 0.43 713001.0 111000.0 0.84 0.9038 0.9523 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I23 compound treatment 630081.0 71400.0 0.52 557154.0 -44800.0 -0.34 0.1286 0.2064 3131193 CMLD2_000491 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 I24 compound treatment 599032.0 40300.0 0.29 616078.0 14200.0 0.11 0.2845 0.9066 3011157 CMLD2_000492 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J01 compound treatment 481859.0 -76900.0 -0.56 563422.0 -38500.0 -0.29 -0.6042 -0.9537 3131194 CMLD2_000493 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J02 compound treatment 475914.0 -82800.0 -0.61 545349.0 -56600.0 -0.43 -0.7321 -0.9859 3011158 CMLD2_000494 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J03 compound treatment 459192.0 -99500.0 -0.73 535725.0 -66200.0 -0.5 -0.8702 -0.9837 3131195 CMLD2_000495 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C4=O)c5ccc(F)cc5F)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J04 compound treatment 475086.0 -83600.0 -0.61 487394.0 -115000.0 -0.87 -1.0477 -0.9851 3011159 CMLD2_000496 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J05 mock treatment 448295.0 -110000.0 -0.81 546182.0 -55700.0 -0.42 -0.8704 -0.9546 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J06 mock treatment 489824.0 -68900.0 -0.5 599332.0 -2590.0 -0.02 -0.3702 -0.7341 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J07 compound treatment 564751.0 6030.0 0.04 522475.0 -79400.0 -0.6 -0.3956 -0.6537 3131196 CMLD2_000497 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J08 compound treatment 485354.0 -73400.0 -0.54 497080.0 -105000.0 -0.8 -0.9425 -0.9815 3131197 CMLD2_000498 C[C@H](N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J09 compound treatment 528393.0 -30300.0 -0.22 544630.0 -57300.0 -0.44 -0.4646 -0.9511 3011160 CMLD2_000499 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J10 compound treatment 567879.0 9160.0 0.07 607240.0 5320.0 0.04 0.076 0.9708 3131198 CMLD2_000500 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J11 compound treatment 586349.0 27600.0 0.2 631620.0 29700.0 0.23 0.3024 0.9985 3011161 CMLD2_000501 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J12 compound treatment 491984.0 -66700.0 -0.49 644230.0 42300.0 0.32 -0.1178 -0.2016 3131199 CMLD2_000502 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J13 compound treatment 540347.0 -18400.0 -0.13 567361.0 -34600.0 -0.26 -0.2806 -0.9516 3131200 CMLD2_000503 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J14 compound treatment 656954.0 98200.0 0.72 597374.0 -4540.0 -0.03 0.4836 0.6724 3011162 CMLD2_000504 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J15 compound treatment 643885.0 85200.0 0.62 587208.0 -14700.0 -0.11 0.3614 0.5711 3131201 CMLD2_000505 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J16 compound treatment 501411.0 -57300.0 -0.42 687227.0 85300.0 0.65 0.1619 0.2098 3011163 CMLD2_000506 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J17 compound treatment 671313.0 113000.0 0.82 589814.0 -12100.0 -0.09 0.5172 0.6243 3131202 CMLD2_000507 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J18 compound treatment 625341.0 66600.0 0.49 539303.0 -62600.0 -0.48 0.0082 0.012 3011164 CMLD2_000508 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J19 compound treatment 681421.0 123000.0 0.9 620182.0 18300.0 0.14 0.7326 0.8069 3131320 CMLD2_000509 CCN1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)C=CC3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J20 compound treatment 577205.0 18500.0 0.14 707788.0 106000.0 0.8 0.6643 0.8145 3131321 CMLD2_000510 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J21 mock treatment 642767.0 84000.0 0.61 629896.0 28000.0 0.21 0.5849 0.8994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J22 mock treatment 697867.0 139000.0 1.02 665262.0 63300.0 0.48 1.0598 0.9415 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J23 compound treatment 631125.0 72400.0 0.53 744524.0 143000.0 1.08 1.1405 0.9458 1952481 CMLD2_000511 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 J24 compound treatment 610528.0 51800.0 0.38 677572.0 75700.0 0.57 0.6743 0.9796 3131322 CMLD2_000512 CO[C@@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K01 compound treatment 456664.0 -102000.0 -0.75 593880.0 -8040.0 -0.06 -0.5709 -0.7624 3131323 CMLD2_000513 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K02 compound treatment 512100.0 -46600.0 -0.34 591511.0 -10400.0 -0.08 -0.297 -0.8486 3011055 CMLD2_000514 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K03 compound treatment 527513.0 -31200.0 -0.23 520357.0 -81600.0 -0.62 -0.5995 -0.9079 3131324 CMLD2_000515 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K04 compound treatment 606305.0 47600.0 0.35 644252.0 42300.0 0.32 0.4735 0.9992 3011057 CMLD2_000516 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K05 compound treatment 531014.0 -27700.0 -0.2 589258.0 -12700.0 -0.1 -0.2113 -0.942 3131325 CMLD2_000517 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K06 compound treatment 497625.0 -61100.0 -0.45 550539.0 -51400.0 -0.39 -0.5919 -0.9977 3131326 CMLD2_000518 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K07 mock treatment 571881.0 13200.0 0.1 600798.0 -1120.0 -0.01 0.062 0.6421 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K08 mock treatment 551364.0 -7350.0 -0.05 577543.0 -24400.0 -0.19 -0.169 -0.8763 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K09 compound treatment 667451.0 109000.0 0.8 622579.0 20700.0 0.16 0.6733 0.8307 3011058 CMLD2_000519 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K10 compound treatment 508007.0 -50700.0 -0.37 582440.0 -19500.0 -0.15 -0.3669 -0.9188 3131327 CMLD2_000520 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K11 compound treatment 645617.0 86900.0 0.64 654833.0 52900.0 0.4 0.7336 0.9756 3011059 CMLD2_000521 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K12 compound treatment 619169.0 60500.0 0.44 558631.0 -43300.0 -0.33 0.0801 0.1453 3131328 CMLD2_000522 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K13 compound treatment 588180.0 29500.0 0.22 665526.0 63600.0 0.48 0.494 0.9338 3131329 CMLD2_000523 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K14 compound treatment 564596.0 5880.0 0.04 643005.0 41100.0 0.31 0.2511 0.797 3011060 CMLD2_000524 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(c6ccccc6)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K15 mock treatment 563238.0 4520.0 0.03 660101.0 58200.0 0.44 0.3359 0.7579 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K16 mock treatment 555164.0 -3550.0 -0.03 660549.0 58600.0 0.45 0.2966 0.6647 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K17 compound treatment 502946.0 -55800.0 -0.41 595516.0 -6400.0 -0.05 -0.3228 -0.7859 3131330 CMLD2_000525 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K18 compound treatment 523896.0 -34800.0 -0.25 569965.0 -32000.0 -0.24 -0.3517 -0.9997 3011061 CMLD2_000526 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K19 compound treatment 550685.0 -8030.0 -0.06 624617.0 22700.0 0.17 0.0804 0.4413 3131331 CMLD2_000527 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K20 compound treatment 637566.0 78800.0 0.58 593776.0 -8140.0 -0.06 0.364 0.6277 3011062 CMLD2_000528 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K21 compound treatment 650465.0 91700.0 0.67 632706.0 30800.0 0.23 0.6398 0.9005 3011070 CMLD2_000529 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K22 compound treatment 684831.0 126000.0 0.92 753469.0 152000.0 1.15 1.4662 0.994 3011072 CMLD2_000530 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)COC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K23 mock treatment 629450.0 70700.0 0.52 611650.0 9730.0 0.07 0.418 0.8 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 K24 mock treatment 565173.0 6450.0 0.05 620059.0 18100.0 0.14 0.1308 0.8981 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L01 compound treatment 481364.0 -77400.0 -0.57 639916.0 38000.0 0.29 -0.1959 -0.3085 3131332 CMLD2_000531 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L02 compound treatment 435321.0 -123000.0 -0.9 480724.0 -121000.0 -0.92 -1.2891 -0.9999 3131333 CMLD2_000532 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L03 compound treatment 484996.0 -73700.0 -0.54 553501.0 -48400.0 -0.37 -0.6413 -0.9826 3011074 CMLD2_000533 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L04 compound treatment 654203.0 95500.0 0.7 608722.0 6800.0 0.05 0.5303 0.7574 3131334 CMLD2_000534 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L05 compound treatment 527903.0 -30800.0 -0.23 532923.0 -69000.0 -0.52 -0.53 -0.9289 3131335 CMLD2_000535 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L06 compound treatment 504660.0 -54100.0 -0.4 520307.0 -81600.0 -0.62 -0.7179 -0.9764 3011078 CMLD2_000536 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L07 mock treatment 524488.0 -34200.0 -0.25 492803.0 -109000.0 -0.83 -0.7632 -0.8813 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L08 mock treatment 508204.0 -50500.0 -0.37 444746.0 -157000.0 -1.19 -1.1055 -0.8845 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L09 compound treatment 537623.0 -21100.0 -0.15 637487.0 35600.0 0.27 0.082 0.2635 3011128 CMLD2_000537 CC(C)(C)N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L10 compound treatment 598075.0 39400.0 0.29 667112.0 65200.0 0.5 0.5537 0.9667 3131336 CMLD2_000538 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L11 compound treatment 620379.0 61700.0 0.45 585788.0 -16100.0 -0.12 0.2322 0.4969 3011131 CMLD2_000539 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L12 compound treatment 549454.0 -9260.0 -0.07 593879.0 -8040.0 -0.06 -0.0911 -0.9987 3131337 CMLD2_000540 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L13 compound treatment 610298.0 51600.0 0.38 667814.0 65900.0 0.5 0.6207 0.9903 3131338 CMLD2_000541 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C5CCCCC5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L14 compound treatment 572228.0 13500.0 0.1 650714.0 48800.0 0.37 0.332 0.8654 3011134 CMLD2_000542 CC(C)CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L15 mock treatment 563774.0 5060.0 0.04 654889.0 53000.0 0.4 0.3107 0.7688 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L16 mock treatment 635656.0 76900.0 0.56 647463.0 45500.0 0.35 0.6425 0.9727 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L17 compound treatment 519924.0 -38800.0 -0.28 649279.0 47400.0 0.36 0.0538 0.1174 3131454 CMLD2_000543 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L18 compound treatment 506251.0 -52500.0 -0.38 562858.0 -39100.0 -0.3 -0.4811 -0.9919 3011136 CMLD2_000544 CC[C@@H](c1ccccc1)n2c(=O)n3CC[C@H]4[C@H]([C@H](O)[C@@H]5O[C@@H]5C4=O)n3c2=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L19 compound treatment 530808.0 -27900.0 -0.2 580547.0 -21400.0 -0.16 -0.2591 -0.9936 3131455 CMLD2_000545 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L20 compound treatment 587765.0 29000.0 0.21 653724.0 51800.0 0.39 0.4285 0.9581 3131456 CMLD2_000546 C[C@@H]1NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)C/C=C/[C@@H](C)[C@@H](COC1=O)NS(=O)(=O)c2ccc(C)cc2)NS(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L21 compound treatment 587831.0 29100.0 0.21 699986.0 98100.0 0.74 0.6773 0.8742 3011138 CMLD2_000547 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L22 compound treatment 529332.0 -29400.0 -0.21 685601.0 83700.0 0.64 0.2976 0.4434 3131457 CMLD2_000548 CO[C@H]1COC(=O)[C@@H](C)COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L23 mock treatment 608471.0 49800.0 0.36 675905.0 74000.0 0.56 0.6547 0.9778 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 L24 mock treatment 593701.0 35000.0 0.26 689394.0 87500.0 0.66 0.6508 0.9139 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M01 compound treatment 530503.0 -28200.0 -0.21 587734.0 -14200.0 -0.11 -0.2221 -0.9541 3011140 CMLD2_000549 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M02 compound treatment 518757.0 -40000.0 -0.29 616124.0 14200.0 0.11 -0.1303 -0.4184 3131458 CMLD2_000550 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M03 compound treatment 606629.0 47900.0 0.35 608907.0 6990.0 0.05 0.2853 0.8051 3131459 CMLD2_000551 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M04 compound treatment 508998.0 -49700.0 -0.36 602440.0 521.0 0.0 -0.2543 -0.6994 3011143 CMLD2_000552 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M05 compound treatment 546009.0 -12700.0 -0.09 500565.0 -101000.0 -0.77 -0.6102 -0.7868 3011168 CMLD2_000553 O[C@@H]1C/C(=N\OCCCC#C)/[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M06 compound treatment 643163.0 84400.0 0.62 554923.0 -47000.0 -0.36 0.1842 0.2583 3131460 CMLD2_000554 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M07 compound treatment 518696.0 -40000.0 -0.29 616683.0 14800.0 0.11 -0.1277 -0.4073 3011171 CMLD2_000555 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M08 compound treatment 553480.0 -5240.0 -0.04 529545.0 -72400.0 -0.55 -0.4159 -0.7545 3131461 CMLD2_000556 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M09 mock treatment 726457.0 168000.0 1.23 547794.0 -54100.0 -0.41 0.5767 0.4457 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M10 mock treatment 555865.0 -2850.0 -0.02 533562.0 -68400.0 -0.52 -0.3819 -0.7349 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M11 compound treatment 587874.0 29200.0 0.21 555667.0 -46300.0 -0.35 -0.0977 -0.2377 3011173 CMLD2_000557 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C4CCCCC4)C3=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M12 compound treatment 656222.0 97500.0 0.71 606132.0 4210.0 0.03 0.5268 0.7381 3131462 CMLD2_000558 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(CC)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M13 mock treatment 665324.0 107000.0 0.78 573038.0 -28900.0 -0.22 0.3961 0.4891 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M14 mock treatment 645073.0 86400.0 0.63 601962.0 43.5 0.0 0.4468 0.7075 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M15 compound treatment 714672.0 156000.0 1.14 659135.0 57200.0 0.43 1.1138 0.9126 3131463 CMLD2_000559 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(C)c4=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M16 compound treatment 598327.0 39600.0 0.29 521373.0 -80500.0 -0.61 -0.2278 -0.3366 3011176 CMLD2_000560 O[C@@H]1[C@@H]2O[C@@H]2C(=O)C3=CC[C@@H]4[C@H]([C@@H]13)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M17 compound treatment 564798.0 6080.0 0.04 710375.0 108000.0 0.82 0.614 0.7442 3131464 CMLD2_000561 O[C@@H]1CC(=O)[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M18 compound treatment 705244.0 147000.0 1.07 628840.0 26900.0 0.2 0.9023 0.8271 3011178 CMLD2_000562 Cn1c(=O)n2CC[C@H]3[C@H]([C@H](O)[C@@H]4O[C@@H]4C3=O)n2c1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M19 compound treatment 719859.0 161000.0 1.18 722361.0 120000.0 0.91 1.4803 0.9922 3131465 CMLD2_000563 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M20 compound treatment 667964.0 109000.0 0.8 592642.0 -9280.0 -0.07 0.5151 0.6422 3011181 CMLD2_000564 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M21 compound treatment 602170.0 43500.0 0.32 664394.0 62500.0 0.47 0.5603 0.981 3131466 CMLD2_000565 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](COCc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M22 compound treatment 683455.0 125000.0 0.91 677530.0 75600.0 0.57 1.0512 0.9751 3011183 CMLD2_000566 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M23 compound treatment 625569.0 66900.0 0.49 725125.0 123000.0 0.94 1.0075 0.9541 3131467 CMLD2_000567 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 M24 compound treatment 624530.0 65800.0 0.48 631564.0 29600.0 0.23 0.4996 0.9401 3131468 CMLD2_000568 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N01 compound treatment 545629.0 -13100.0 -0.1 618267.0 16300.0 0.12 0.0201 0.1284 3131469 CMLD2_000569 CC(=CCC/C(=C/CO\N=C\1/C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4ccc(F)cc4F)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N02 compound treatment 529024.0 -29700.0 -0.22 582561.0 -19400.0 -0.15 -0.2575 -0.982 3011201 CMLD2_000570 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccccc5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N03 compound treatment 577263.0 18500.0 0.14 660594.0 58700.0 0.45 0.4111 0.8823 3131470 CMLD2_000571 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N04 compound treatment 612055.0 53300.0 0.39 613753.0 11800.0 0.09 0.3394 0.8479 3131471 CMLD2_000572 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N05 compound treatment 575059.0 16300.0 0.12 693986.0 92100.0 0.7 0.5791 0.8161 3011203 CMLD2_000573 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N06 compound treatment 590966.0 32200.0 0.24 541227.0 -60700.0 -0.46 -0.1593 -0.3075 3131472 CMLD2_000574 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N07 compound treatment 615414.0 56700.0 0.41 635458.0 33500.0 0.25 0.4733 0.9727 3011205 CMLD2_000575 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N08 compound treatment 543216.0 -15500.0 -0.11 567018.0 -34900.0 -0.27 -0.2676 -0.9282 3131588 CMLD2_000576 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N09 mock treatment 634065.0 75300.0 0.55 577208.0 -24700.0 -0.19 0.2569 0.4413 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N10 mock treatment 684767.0 126000.0 0.92 606171.0 4250.0 0.03 0.6747 0.7314 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N11 compound treatment 710622.0 152000.0 1.11 669538.0 67600.0 0.51 1.1487 0.9386 3011207 CMLD2_000577 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C4CCCCC4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N12 compound treatment 709050.0 150000.0 1.1 704125.0 102000.0 0.78 1.3264 0.9855 3131589 CMLD2_000578 CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/NC(=O)OCc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N13 mock treatment 587620.0 28900.0 0.21 598571.0 -3350.0 -0.03 0.1315 0.6176 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N14 mock treatment 651806.0 93100.0 0.68 635115.0 33200.0 0.25 0.6597 0.9087 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N15 compound treatment 652548.0 93800.0 0.69 644945.0 43000.0 0.33 0.7163 0.9425 3131590 CMLD2_000579 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OCCCC#C)n2c1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N16 compound treatment 158751.0 -400000.0 -2.93 156017.0 -446000.0 -3.39 -4.4636 -0.9973 3011210 CMLD2_000580 C[C@@H](N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N17 compound treatment 645797.0 87100.0 0.64 689375.0 87500.0 0.66 0.9201 0.9998 3131591 CMLD2_000581 C[C@H](N1C(=O)[C@@H]2CC[C@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N18 compound treatment 593972.0 35300.0 0.26 565924.0 -36000.0 -0.27 -0.0111 -0.0294 3011211 CMLD2_000582 O[C@@H]1[C@@H]2O[C@@H]2C(=O)[C@H]3CCn4n([C@@H]13)c(=O)n(Cc5cc6OCOc6cc5Cl)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N19 compound treatment 641969.0 83300.0 0.61 702032.0 100000.0 0.76 0.9683 0.9939 3131592 CMLD2_000583 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@H](C)COC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N20 compound treatment 655029.0 96300.0 0.7 640870.0 39000.0 0.3 0.7073 0.9258 3131593 CMLD2_000584 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N21 compound treatment 699216.0 140000.0 1.03 714437.0 113000.0 0.85 1.331 0.9958 3011214 CMLD2_000585 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@H](C)C(=O)OC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N22 compound treatment 621726.0 63000.0 0.46 614292.0 12400.0 0.09 0.3923 0.8342 3011226 CMLD2_000586 CO[C@H]1COC(=O)[C@H](C)COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N23 compound treatment 693693.0 135000.0 0.99 697460.0 95500.0 0.73 1.2112 0.9886 3131594 CMLD2_000587 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@@H]3CCCN3C(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 N24 compound treatment 664142.0 105000.0 0.77 703711.0 102000.0 0.77 1.092 1.0 3131054 CMLD2_000588 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O01 compound treatment 571602.0 12900.0 0.09 566676.0 -35200.0 -0.27 -0.1227 -0.4323 3131595 CMLD2_000589 O[C@@H]1C/C(=N\OCCCC#C)/[C@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O02 compound treatment 492144.0 -66600.0 -0.49 595423.0 -6500.0 -0.05 -0.3792 -0.7748 3011229 CMLD2_000590 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccccc5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O03 compound treatment 517329.0 -41400.0 -0.3 555585.0 -46300.0 -0.35 -0.4629 -0.9972 3131596 CMLD2_000591 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O04 compound treatment 501505.0 -57200.0 -0.42 563042.0 -38900.0 -0.3 -0.5047 -0.9855 3011196 CMLD2_000592 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5cccc(Oc6ccccc6)c5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O05 compound treatment 629654.0 70900.0 0.52 593138.0 -8780.0 -0.07 0.3197 0.6112 3131597 CMLD2_000593 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(Cc4ccc5OCOc5c4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O06 compound treatment 588357.0 29600.0 0.22 569233.0 -32700.0 -0.25 -0.0223 -0.0677 3131598 CMLD2_000594 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N([C@@H](C)c4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O07 compound treatment 602616.0 43900.0 0.32 605267.0 3350.0 0.03 0.245 0.7608 3011231 CMLD2_000595 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C[C@@H]5CCCO5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O08 compound treatment 620808.0 62100.0 0.45 641955.0 40000.0 0.3 0.5361 0.981 3131599 CMLD2_000596 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O09 compound treatment 653249.0 94500.0 0.69 759764.0 158000.0 1.2 1.3367 0.9658 3011237 CMLD2_000597 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)C(C)(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O10 compound treatment 651659.0 92900.0 0.68 734352.0 132000.0 1.01 1.192 0.9818 3131600 CMLD2_000598 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O11 mock treatment 616885.0 58200.0 0.43 701848.0 99900.0 0.76 0.8376 0.9625 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O12 mock treatment 730479.0 172000.0 1.26 654913.0 53000.0 0.4 1.1729 0.8892 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O13 compound treatment 632048.0 73300.0 0.54 628411.0 26500.0 0.2 0.5215 0.9105 3011239 CMLD2_000599 OC[C@H]1O[C@@H](O/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(C5CCCCC5)C4=O)[C@H](O)[C@@H](O)[C@@H]1O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O14 compound treatment 453812.0 -105000.0 -0.77 546953.0 -55000.0 -0.42 -0.8377 -0.9591 3131601 CMLD2_000600 CC(=CCC/C(=C/CO\N=C\1/[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)/C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O15 compound treatment 784996.0 226000.0 1.65 647392.0 45500.0 0.35 1.4144 0.8367 3131602 CMLD2_000601 Cn1c(=O)n2CC[C@H]/3[C@H]([C@H](O)[C@@H]4O[C@@H]4\C3=N/OC[C@@H](O)COCc5ccco5)n2c1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O16 compound treatment 480560.0 -78200.0 -0.57 572156.0 -29800.0 -0.23 -0.564 -0.9176 3012175 CMLD2_000602 CCOC(=O)CCN1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O17 compound treatment 705252.0 147000.0 1.07 669925.0 68000.0 0.52 1.1231 0.944 3012176 CMLD2_000603 O[C@@H]1CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@H]2[C@@H]1O)C(=O)N(C[C@@H]4CCCO4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O18 compound treatment 625044.0 66300.0 0.49 785173.0 183000.0 1.39 1.3274 0.9004 3012177 CMLD2_000604 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(Cc4ccccc4)C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O19 compound treatment 653023.0 94300.0 0.69 653378.0 51500.0 0.39 0.7641 0.9638 3012178 CMLD2_000605 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O20 compound treatment 655065.0 96300.0 0.7 664670.0 62800.0 0.48 0.8353 0.9819 3012179 CMLD2_000606 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](OCc2ccccc2)\C=C\[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O21 compound treatment 696622.0 138000.0 1.01 687125.0 85200.0 0.65 1.1708 0.977 3131603 CMLD2_000607 CO[C@@H]1/C=C/CC(=O)N2CCC[C@H]2C(=O)OC[C@@H](C)C(=O)OC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O22 compound treatment 683526.0 125000.0 0.91 712228.0 110000.0 0.84 1.238 0.9991 3011105 CMLD2_000608 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O23 compound treatment 670128.0 111000.0 0.81 691735.0 89800.0 0.68 1.0586 0.9961 3012180 CMLD2_000609 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 O24 compound treatment 609915.0 51200.0 0.37 639748.0 37800.0 0.29 0.468 0.9915 3131604 CMLD2_000610 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P01 compound treatment 568746.0 10000.0 0.07 585440.0 -16500.0 -0.13 -0.0367 -0.2527 3131605 CMLD2_000611 O[C@@H](COCc1ccco1)CO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P02 compound treatment 630415.0 71700.0 0.52 660930.0 59000.0 0.45 0.6877 0.997 3012181 CMLD2_000612 O[C@@H]1C/C(=N\OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C4=O)c5ccc(F)cc5F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P03 compound treatment 549390.0 -9330.0 -0.07 606556.0 4640.0 0.04 -0.0233 -0.3038 3131606 CMLD2_000613 CCOC(=O)N/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P04 compound treatment 613959.0 55200.0 0.4 665221.0 63300.0 0.48 0.6257 0.9962 3012182 CMLD2_000614 CC(C)CO/N=C/1\C[C@@H](O)[C@@H](O)[C@@H]2[C@H]3[C@@H](CC[C@H]21)C(=O)N(C3=O)c4cccc(Oc5ccccc5)c4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P05 compound treatment 534595.0 -24100.0 -0.18 574333.0 -27600.0 -0.21 -0.2729 -0.9963 3131723 CMLD2_000615 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(Cc5ccc6OCOc6c5)C4=O)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P06 compound treatment 625360.0 66600.0 0.49 620765.0 18800.0 0.14 0.4459 0.8777 3131724 CMLD2_000616 C[C@H](N1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC\C=C(/C)\CCC=C(C)C)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P07 compound treatment 550268.0 -8450.0 -0.06 555415.0 -46500.0 -0.35 -0.2935 -0.8184 3012183 CMLD2_000617 O[C@@H]1C/C(=N\NC(=O)OCc2ccccc2)/[C@@H]3CC[C@@H]4[C@H]([C@H]3[C@@H]1O)C(=O)N(C[C@@H]5CCCO5)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P08 compound treatment 583485.0 24800.0 0.18 624413.0 22500.0 0.17 0.2489 0.9996 3131725 CMLD2_000618 CCOC(=O)CCN1C(=O)[C@@H]2CC[C@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCCCC#C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P09 compound treatment 628464.0 69700.0 0.51 700534.0 98600.0 0.75 0.8904 0.9824 3012184 CMLD2_000619 COc1ccc(COC(=O)N/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@@H]32)C(=O)N(C4=O)C(C)(C)C)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P10 compound treatment 627132.0 68400.0 0.5 645096.0 43200.0 0.33 0.5857 0.979 3131726 CMLD2_000620 CC(C)(C)N1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P11 mock treatment 643006.0 84300.0 0.62 660944.0 59000.0 0.45 0.7529 0.9878 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P12 mock treatment 588879.0 30200.0 0.22 692454.0 90500.0 0.69 0.6423 0.8893 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P13 compound treatment 675007.0 116000.0 0.85 755511.0 154000.0 1.17 1.4264 0.9879 3131727 CMLD2_000621 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P14 compound treatment 616256.0 57500.0 0.42 748652.0 147000.0 1.11 1.0857 0.9113 3012185 CMLD2_000622 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCCCC#C)/[C@H]3CCn4n([C@@H]13)c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P15 compound treatment 686805.0 128000.0 0.94 653869.0 52000.0 0.39 0.9414 0.9262 3131728 CMLD2_000623 O[C@@H]1[C@@H]2O[C@@H]2/C(=N\OCc3ccccc3)/[C@H]4CCn5n([C@@H]14)c(=O)n(Cc6cc7OCOc7cc6Cl)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P16 compound treatment 172705.0 -386000.0 -2.82 171787.0 -430000.0 -3.27 -4.3067 -0.9973 3012186 CMLD2_000624 CC(C)(C)N1C(=O)[C@@H]2CC=C3[C@@H]([C@@H]2C1=O)[C@H](O)[C@@H]4O[C@@H]4C3=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P17 compound treatment 722965.0 164000.0 1.2 657884.0 56000.0 0.43 1.15 0.9025 3131729 CMLD2_000625 C[C@H](N1C(=O)[C@@H]2CC[C@@H]3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)CC3=O)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P18 compound treatment 677852.0 119000.0 0.87 680436.0 78500.0 0.6 1.0378 0.9829 3012187 CMLD2_000626 O[C@@H]1C=CC(=O)[C@@H]2CC[C@@H]3[C@H]([C@@H]12)C(=O)N(C3=O)c4ccc(F)cc4F 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P19 compound treatment 680527.0 122000.0 0.89 746067.0 144000.0 1.1 1.4042 0.9948 3131730 CMLD2_000627 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)C/C=C/[C@H]1C)[C@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P20 compound treatment 678621.0 120000.0 0.88 741974.0 140000.0 1.06 1.3724 0.9954 3012188 CMLD2_000628 C[C@H]/1COC(=O)C\C=C\[C@@H](C)[C@H]2O[C@H](COC(=O)C\C=C1)[C@@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P21 compound treatment 655896.0 97200.0 0.71 695733.0 93800.0 0.71 1.0065 1.0 3131731 CMLD2_000629 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P22 compound treatment 606319.0 47600.0 0.35 729003.0 127000.0 0.97 0.9288 0.905 3012189 CMLD2_000630 CSCC[C@@H]1NC(=O)C/C=C/[C@@H](C)COC(=O)[C@H](C)COC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P23 compound treatment 727404.0 169000.0 1.23 710071.0 108000.0 0.82 1.4533 0.9805 3131732 CMLD2_000631 CO[C@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](OCc3ccccc3)/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2110 P24 compound treatment 677573.0 119000.0 0.87 743125.0 141000.0 1.07 1.3731 0.9946 3131733 CMLD2_000632 CO[C@H]1COC(=O)C/C=C/[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A01 compound treatment 352704.0 -214000.0 -1.56 504454.0 -63900.0 -0.49 -1.4485 -0.8851 3012190 CMLD2_000633 CO[C@@H]1COC(=O)[C@@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A02 compound treatment 308921.0 -257000.0 -1.88 453562.0 -115000.0 -0.87 -1.9483 -0.9388 3131321 CMLD2_000634 C[C@@H]1/C=C/CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)/C=C/CC(=O)OC[C@H]3O[C@H]1C=C[C@@H]3O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A03 compound treatment 412338.0 -154000.0 -1.13 568544.0 152.0 0.0 -0.7958 -0.7064 3131734 CMLD2_000635 CO[C@@H]1COC(=O)[C@@H](C)NC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A04 compound treatment 407402.0 -159000.0 -1.16 494715.0 -73700.0 -0.56 -1.218 -0.9438 3131735 CMLD2_000636 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A05 compound treatment 469926.0 -96500.0 -0.71 478547.0 -89800.0 -0.68 -0.9815 -0.9999 3012191 CMLD2_000637 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A06 compound treatment 500926.0 -65500.0 -0.48 547058.0 -21300.0 -0.16 -0.4532 -0.8965 3131736 CMLD2_000638 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A07 compound treatment 493286.0 -73100.0 -0.53 505478.0 -62900.0 -0.48 -0.716 -0.9984 3012192 CMLD2_000639 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A08 compound treatment 479524.0 -86900.0 -0.64 547288.0 -21100.0 -0.16 -0.5626 -0.8586 3131737 CMLD2_000640 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A09 compound treatment 571340.0 4940.0 0.04 494198.0 -74200.0 -0.56 -0.373 -0.6604 3131738 CMLD2_000641 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)cc2)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A10 compound treatment 571573.0 5180.0 0.04 536429.0 -32000.0 -0.24 -0.1449 -0.5898 3012193 CMLD2_000642 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A11 compound treatment 524030.0 -42400.0 -0.31 529443.0 -38900.0 -0.3 -0.4283 -0.9997 3131739 CMLD2_000643 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A12 compound treatment 628973.0 62600.0 0.46 560513.0 -7880.0 -0.06 0.2813 0.6094 3012194 CMLD2_000644 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A13 mock treatment 499798.0 -66600.0 -0.49 504683.0 -63700.0 -0.48 -0.6866 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A14 mock treatment 582931.0 16500.0 0.12 496237.0 -72200.0 -0.55 -0.3021 -0.5382 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A15 compound treatment 618072.0 51700.0 0.38 498827.0 -69600.0 -0.53 -0.1065 -0.1639 3131740 CMLD2_000645 CCc1cc2CN(CC/C(=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A16 compound treatment 580052.0 13700.0 0.1 455521.0 -113000.0 -0.86 -0.5357 -0.6206 3131741 CMLD2_000646 CCc1cc2CN(CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A17 compound treatment 664996.0 98600.0 0.72 533158.0 -35200.0 -0.27 0.3206 0.4168 3012195 CMLD2_000647 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cc(no5)c6c(C)cc(C)cc6C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A18 compound treatment 492557.0 -73800.0 -0.54 524350.0 -44000.0 -0.33 -0.6184 -0.9735 3131860 CMLD2_000648 CO[C@H](/C=N/O[C@@H](C)c1cc(no1)c2c(C)cc(C)cc2C)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A19 compound treatment 629178.0 62800.0 0.46 462870.0 -106000.0 -0.8 -0.2422 -0.2622 3012196 CMLD2_000649 C[C@H](ON=C(C)C)c1cc(no1)c2c(C)cc(C)cc2C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A20 compound treatment 626316.0 59900.0 0.44 495231.0 -73200.0 -0.56 -0.0832 -0.1175 3131861 CMLD2_000650 CO/N=C/[C@@H](C)[C@H](OCc1ccccc1)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A21 compound treatment 488243.0 -78200.0 -0.57 491445.0 -76900.0 -0.58 -0.8175 -0.9999 3131714 CMLD2_000651 COC(=O)C1=C(C)N(Cc2ccccc2)[C@]3(O[C@]4([C@H]5CCCC(=O)[C@H]53)C(=O)OC)N([C@@H]1c6ccccc6)C4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A22 compound treatment 546160.0 -20200.0 -0.15 515695.0 -52700.0 -0.4 -0.3877 -0.9084 3012197 CMLD2_000652 C[C@@H]1CC[C@@H]2N(C[C@@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A23 mock treatment 528809.0 -37600.0 -0.27 536457.0 -31900.0 -0.24 -0.3659 -0.9981 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 A24 mock treatment 554145.0 -12300.0 -0.09 418381.0 -150000.0 -1.14 -0.8692 -0.7604 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B01 compound treatment 328558.0 -238000.0 -1.74 525531.0 -42900.0 -0.33 -1.4601 -0.8251 3131862 CMLD2_000653 CO[C@H]1COC(=O)C/C=C/[C@H](C)COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B02 compound treatment 311946.0 -254000.0 -1.86 500890.0 -67500.0 -0.51 -1.6784 -0.8696 3011062 CMLD2_000654 C[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](Cc2ccccc2)NC1=O)NS(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B03 compound treatment 521904.0 -44500.0 -0.33 456857.0 -112000.0 -0.85 -0.8292 -0.9136 3131863 CMLD2_000655 CO[C@@H]1COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B04 compound treatment 469266.0 -97100.0 -0.71 463945.0 -104000.0 -0.79 -1.0633 -0.9985 3012198 CMLD2_000656 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B05 compound treatment 539732.0 -26700.0 -0.2 531156.0 -37200.0 -0.28 -0.3379 -0.9835 3131864 CMLD2_000657 C[C@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cc(no4)c5c(C)cc(C)cc5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B06 compound treatment 510625.0 -55800.0 -0.41 473396.0 -95000.0 -0.72 -0.7987 -0.9635 3131865 CMLD2_000658 C[C@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cc(no2)c3c(C)cc(C)cc3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B07 compound treatment 527942.0 -38500.0 -0.28 533623.0 -34800.0 -0.26 -0.3856 -0.9995 3012199 CMLD2_000659 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B08 compound treatment 533559.0 -32800.0 -0.24 515195.0 -53200.0 -0.4 -0.4556 -0.9691 3131866 CMLD2_000660 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B09 compound treatment 437984.0 -128000.0 -0.94 448323.0 -120000.0 -0.91 -1.309 -0.9999 3131867 CMLD2_000661 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B10 compound treatment 491504.0 -74900.0 -0.55 511755.0 -56600.0 -0.43 -0.6915 -0.9929 3012228 CMLD2_000662 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B11 compound treatment 566010.0 -387.0 0.0 466303.0 -102000.0 -0.78 -0.5504 -0.7097 3131868 CMLD2_000663 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B12 compound treatment 554491.0 -11900.0 -0.09 428282.0 -140000.0 -1.06 -0.8142 -0.7624 3130911 CMLD2_000664 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)COCc4ccco4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B13 mock treatment 543896.0 -22500.0 -0.16 496677.0 -71700.0 -0.54 -0.5016 -0.8814 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B14 mock treatment 598298.0 31900.0 0.23 483806.0 -84600.0 -0.64 -0.2894 -0.4233 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B15 compound treatment 601017.0 34600.0 0.25 478514.0 -89900.0 -0.68 -0.3038 -0.4172 3131869 CMLD2_000665 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(CC)c(CC)cc3C2)C=C[C@@H]1Oc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B16 compound treatment 635054.0 68700.0 0.5 577630.0 9240.0 0.07 0.4047 0.7982 3012230 CMLD2_000666 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B17 compound treatment 664024.0 97600.0 0.71 565203.0 -3190.0 -0.02 0.4877 0.6827 3131870 CMLD2_000667 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B18 compound treatment 562215.0 -4180.0 -0.03 563628.0 -4760.0 -0.04 -0.0472 -0.9965 3012231 CMLD2_000668 CO[C@H](/C=N/OC[C@@H](C)[C@H](OCc1ccccc1)C(C)C)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B19 compound treatment 585089.0 18700.0 0.14 541449.0 -26900.0 -0.2 -0.0481 -0.1953 3131871 CMLD2_000669 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CON=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B20 compound treatment 606103.0 39700.0 0.29 547130.0 -21300.0 -0.16 0.0911 0.2742 3012232 CMLD2_000670 CCc1cc2CN(CC/C(=N/OC)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B21 compound treatment 147950.0 -418000.0 -3.06 125222.0 -443000.0 -3.37 -4.5444 -0.9989 3131872 CMLD2_000671 C[C@@H]1CC[C@@H]2N(C[C@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B22 compound treatment 508850.0 -57500.0 -0.42 581618.0 13200.0 0.1 -0.2265 -0.5236 3131873 CMLD2_000672 COc1ccc(OC[C@H]2CN3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B23 mock treatment 714095.0 148000.0 1.08 583796.0 15400.0 0.12 0.8465 0.7792 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 B24 mock treatment 601760.0 35400.0 0.26 468625.0 -99800.0 -0.76 -0.3531 -0.4409 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C01 compound treatment 305925.0 -260000.0 -1.9 499379.0 -69000.0 -0.52 -1.7177 -0.8694 3012233 CMLD2_000673 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C02 compound treatment 378881.0 -188000.0 -1.37 483870.0 -84500.0 -0.64 -1.4237 -0.9402 3011181 CMLD2_000674 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C03 compound treatment 510903.0 -55500.0 -0.41 484966.0 -83400.0 -0.63 -0.7351 -0.9768 3131874 CMLD2_000675 CO[C@@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C04 compound treatment 545125.0 -21300.0 -0.16 595012.0 26600.0 0.2 0.033 0.1293 3131875 CMLD2_000676 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C05 compound treatment 545859.0 -20500.0 -0.15 497150.0 -71200.0 -0.54 -0.4889 -0.8704 3012234 CMLD2_000677 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C06 compound treatment 402097.0 -164000.0 -1.2 536099.0 -32300.0 -0.25 -1.0231 -0.8343 3131876 CMLD2_000678 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C07 compound treatment 459181.0 -107000.0 -0.78 580153.0 11800.0 0.09 -0.4913 -0.6225 3131877 CMLD2_000679 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C08 compound treatment 542340.0 -24100.0 -0.18 555257.0 -13100.0 -0.1 -0.195 -0.9639 3012270 CMLD2_000680 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)cc2)c6ccc(C)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C09 compound treatment 501004.0 -65400.0 -0.48 551267.0 -17100.0 -0.13 -0.4302 -0.8679 3131878 CMLD2_000681 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C10 compound treatment 491147.0 -75300.0 -0.55 563331.0 -5060.0 -0.04 -0.4163 -0.7547 3131879 CMLD2_000682 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C11 mock treatment 523316.0 -43100.0 -0.32 492480.0 -75900.0 -0.58 -0.6306 -0.9596 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C12 mock treatment 531886.0 -34500.0 -0.25 544942.0 -23500.0 -0.18 -0.3044 -0.9855 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C13 compound treatment 541017.0 -25400.0 -0.19 488557.0 -79800.0 -0.61 -0.5601 -0.8831 3012273 CMLD2_000683 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C14 compound treatment 477296.0 -89100.0 -0.65 517049.0 -51300.0 -0.39 -0.7366 -0.9699 3131994 CMLD2_000684 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C15 mock treatment 636026.0 69600.0 0.51 565144.0 -3250.0 -0.02 0.3426 0.672 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C16 mock treatment 556141.0 -10300.0 -0.08 579411.0 11000.0 0.08 0.0062 0.0547 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C17 compound treatment 670936.0 105000.0 0.76 596142.0 27700.0 0.21 0.6897 0.8696 3131995 CMLD2_000685 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C18 compound treatment 563139.0 -3260.0 -0.02 608675.0 40300.0 0.31 0.1995 0.6501 3012274 CMLD2_000686 CO[C@H](/C=N/O[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C19 compound treatment 575232.0 8830.0 0.06 526529.0 -41900.0 -0.32 -0.1792 -0.5522 3012275 CMLD2_000687 CC(=NO[C@@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]1OC(=O)C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C20 compound treatment 545210.0 -21200.0 -0.15 591271.0 22900.0 0.17 0.0133 0.0573 3131996 CMLD2_000688 CO/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C21 compound treatment 595196.0 28800.0 0.21 545872.0 -22500.0 -0.17 0.028 0.103 3011349 CMLD2_000689 C[C@@H]1CC[C@@H]2N(C[C@@H](COS(=O)(=O)c3ccc(C)cc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C22 compound treatment 583521.0 17100.0 0.13 577838.0 9450.0 0.07 0.1393 0.9651 3131997 CMLD2_000690 COc1ccc(OC[C@@H]2CC3[C@H]([C@H](C)CC[C@H]3C(=O)O2)c4ccc(Br)cc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C23 mock treatment 535012.0 -31400.0 -0.23 510686.0 -57700.0 -0.44 -0.4723 -0.9544 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 C24 mock treatment 479147.0 -87300.0 -0.64 542791.0 -25600.0 -0.19 -0.5887 -0.8826 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D01 compound treatment 437755.0 -129000.0 -0.94 532650.0 -35700.0 -0.27 -0.8572 -0.8755 3012277 CMLD2_000691 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)[C@H](C)NC(=O)C/C=C/[C@H]1C)[C@@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D02 compound treatment 496054.0 -70300.0 -0.51 431181.0 -137000.0 -1.04 -1.1008 -0.947 3131998 CMLD2_000692 CO[C@@H]1COC(=O)[C@@H](OCc2ccccc2)/C=C/[C@H](C)[C@H](COC(=O)[C@H](CCSC)NC(=O)C\C=C\[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D03 compound treatment 478940.0 -87500.0 -0.64 510425.0 -58000.0 -0.44 -0.7636 -0.9834 3012278 CMLD2_000693 CO[C@@H]1COC(=O)[C@H](CCSC)NC(=O)C/C=C/[C@@H](C)COC(=O)CCC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D04 compound treatment 560646.0 -5750.0 -0.04 491585.0 -76800.0 -0.58 -0.4423 -0.7561 3131999 CMLD2_000694 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D05 compound treatment 527611.0 -38800.0 -0.28 545206.0 -23200.0 -0.18 -0.3251 -0.9737 3132000 CMLD2_000695 CC(=O)OC[C@H]1O[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D06 compound treatment 431121.0 -135000.0 -0.99 490165.0 -78200.0 -0.59 -1.1197 -0.9703 3012279 CMLD2_000696 CC(=O)OC[C@H]1O[C@H](C/C=N/OC2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D07 compound treatment 476432.0 -90000.0 -0.66 609693.0 41300.0 0.31 -0.2434 -0.3339 3132001 CMLD2_000697 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1Oc4ccc(OC)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D08 compound treatment 522206.0 -44200.0 -0.32 600165.0 31800.0 0.24 -0.0578 -0.1434 3132002 CMLD2_000698 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/c2ccc(cc2)C(=O)N3[C@@H](CC[C@H](C)[C@H]3c4ccc(C)cc4)C(=O)OC)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D09 compound treatment 460161.0 -106000.0 -0.78 450941.0 -117000.0 -0.89 -1.1803 -0.9976 3012280 CMLD2_000699 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](NS(=O)(=O)c2ccc(C)cc2)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D10 compound treatment 480871.0 -85500.0 -0.63 530329.0 -38100.0 -0.29 -0.6467 -0.9386 3132003 CMLD2_000700 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D11 mock treatment 533986.0 -32400.0 -0.24 497995.0 -70400.0 -0.53 -0.5458 -0.933 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D12 mock treatment 566014.0 -383.0 0.0 455722.0 -113000.0 -0.86 -0.6072 -0.7094 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D13 compound treatment 560515.0 -5880.0 -0.04 562300.0 -6090.0 -0.05 -0.0631 -0.9993 3012281 CMLD2_000701 CC1(C)O[C@H]2O[C@H]([C@H](O)CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)[C@H](O)[C@H]2O1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D14 compound treatment 456161.0 -110000.0 -0.81 438434.0 -130000.0 -0.99 -1.2681 -0.9949 3132004 CMLD2_000702 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D15 mock treatment 623425.0 57000.0 0.42 513240.0 -55200.0 -0.42 -0.0014 -0.0023 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D16 mock treatment 529958.0 -36400.0 -0.27 546455.0 -21900.0 -0.17 -0.3063 -0.9745 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D17 compound treatment 646536.0 80100.0 0.59 603500.0 35100.0 0.27 0.603 0.9365 3132005 CMLD2_000703 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D18 compound treatment 488708.0 -77700.0 -0.57 557922.0 -10500.0 -0.08 -0.458 -0.7983 3012283 CMLD2_000704 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D19 compound treatment 628210.0 61800.0 0.45 486405.0 -82000.0 -0.62 -0.1208 -0.1569 3132006 CMLD2_000705 C[C@@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D20 compound treatment 595417.0 29000.0 0.21 589216.0 20800.0 0.16 0.2619 0.9895 3012284 CMLD2_000706 CO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D21 compound treatment 574554.0 8160.0 0.06 525376.0 -43000.0 -0.33 -0.1889 -0.5686 3132007 CMLD2_000707 CCCC[C@H]1CN2[C@H]([C@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D22 compound treatment 628467.0 62100.0 0.45 615359.0 47000.0 0.36 0.5733 0.9929 3132008 CMLD2_000708 C[C@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D23 mock treatment 636998.0 70600.0 0.52 521396.0 -47000.0 -0.36 0.1126 0.1794 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 D24 mock treatment 604830.0 38400.0 0.28 514142.0 -54300.0 -0.41 -0.0927 -0.1858 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E01 mock treatment 402148.0 -164000.0 -1.2 471779.0 -96600.0 -0.73 -1.3683 -0.9721 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E02 mock treatment 518958.0 -47400.0 -0.35 498443.0 -69900.0 -0.53 -0.6211 -0.9786 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E03 compound treatment 552833.0 -13600.0 -0.1 558249.0 -10100.0 -0.08 -0.1246 -0.9922 3012286 CMLD2_000709 CO[C@@H]1COC(=O)CCC[C@@H](C)[C@@H](COC(=O)CCC[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E04 compound treatment 539489.0 -26900.0 -0.2 487373.0 -81000.0 -0.62 -0.5744 -0.8889 3132009 CMLD2_000710 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]3OC(=O)C)/C)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E05 compound treatment 501731.0 -64700.0 -0.47 567442.0 -950.0 -0.01 -0.3395 -0.7178 3012287 CMLD2_000711 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E06 compound treatment 568638.0 2240.0 0.02 562069.0 -6320.0 -0.05 -0.0224 -0.4409 3132010 CMLD2_000712 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E07 compound treatment 472788.0 -93600.0 -0.68 534300.0 -34100.0 -0.26 -0.6672 -0.9116 3012333 CMLD2_000713 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E08 compound treatment 387664.0 -179000.0 -1.31 529661.0 -38700.0 -0.29 -1.1323 -0.8451 3132011 CMLD2_000714 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)cc2)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E09 mock treatment 460816.0 -106000.0 -0.77 580259.0 11900.0 0.09 -0.4822 -0.6203 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E10 mock treatment 616074.0 49700.0 0.36 570384.0 1990.0 0.02 0.2676 0.7359 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E11 compound treatment 422417.0 -144000.0 -1.05 506792.0 -61600.0 -0.47 -1.0754 -0.9333 3012334 CMLD2_000715 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E12 compound treatment 534151.0 -32200.0 -0.24 575866.0 7470.0 0.06 -0.1266 -0.522 3132012 CMLD2_000716 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@@H]5COC[C@H]5O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E13 compound treatment 480135.0 -86300.0 -0.63 524368.0 -44000.0 -0.33 -0.6826 -0.9559 3012337 CMLD2_000717 OC[C@H]1O[C@H](CC=C)C=C[C@@H]1O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E14 compound treatment 568878.0 2480.0 0.02 588806.0 20400.0 0.16 0.1225 0.7845 3132130 CMLD2_000718 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC(C)CN2CCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E15 compound treatment 585739.0 19300.0 0.14 676264.0 108000.0 0.82 0.6795 0.8171 3132131 CMLD2_000719 CCc1cc2CN(CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E16 compound treatment 647873.0 81500.0 0.6 599816.0 31400.0 0.24 0.5901 0.9194 3132132 CMLD2_000720 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6)c7ccccc7)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E17 mock treatment 602292.0 35900.0 0.26 600111.0 31700.0 0.24 0.356 0.9991 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E18 mock treatment 620632.0 54200.0 0.4 597434.0 29000.0 0.22 0.4365 0.9617 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E19 compound treatment 568540.0 2140.0 0.02 446153.0 -122000.0 -0.93 -0.6456 -0.6951 3012338 CMLD2_000721 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E20 mock treatment 468169.0 -98200.0 -0.72 662627.0 94200.0 0.72 -0.0017 -0.0017 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E21 compound treatment 599114.0 32700.0 0.24 515795.0 -52600.0 -0.4 -0.1134 -0.2434 3131584 CMLD2_000722 C[C@@H]1CC[C@@H]2N(C[C@@H](CN=[N+]=[N-])OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E22 compound treatment 531012.0 -35400.0 -0.26 590660.0 22300.0 0.17 -0.0634 -0.205 3012339 CMLD2_000723 COC(=O)C/C=C/[C@@H](C)[C@H](OCc1cccc(c1)c2ccccc2)C3CCCCC3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E23 mock treatment 571972.0 5570.0 0.04 536391.0 -32000.0 -0.24 -0.1431 -0.5804 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 E24 mock treatment 518861.0 -47500.0 -0.35 501795.0 -66600.0 -0.51 -0.6036 -0.9832 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F01 mock treatment 457891.0 -109000.0 -0.79 506368.0 -62000.0 -0.47 -0.8943 -0.969 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F02 mock treatment 533249.0 -33100.0 -0.24 579872.0 11500.0 0.09 -0.1097 -0.426 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F03 compound treatment 554725.0 -11700.0 -0.09 482585.0 -85800.0 -0.65 -0.5213 -0.7929 3132133 CMLD2_000724 C[C@H]1/C=C/CC(=O)OC[C@H](NS(=O)(=O)c2ccc(C)cc2)[C@@H](C)/C=C/CC(=O)OC[C@@H]1NS(=O)(=O)c3ccc(C)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F04 compound treatment 524293.0 -42100.0 -0.31 493700.0 -74700.0 -0.57 -0.619 -0.9588 3012198 CMLD2_000725 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F05 compound treatment 513227.0 -53200.0 -0.39 516290.0 -52100.0 -0.4 -0.5548 -1.0 3132134 CMLD2_000726 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F06 compound treatment 426046.0 -140000.0 -1.03 495411.0 -73000.0 -0.55 -1.1178 -0.9582 3012341 CMLD2_000727 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F07 compound treatment 470400.0 -96000.0 -0.7 566230.0 -2160.0 -0.02 -0.508 -0.7235 3132135 CMLD2_000728 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCc4nc(C)c(C)cc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F08 compound treatment 309735.0 -257000.0 -1.88 334027.0 -234000.0 -1.78 -2.5862 -0.9997 3132136 CMLD2_000729 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)cc2)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F09 mock treatment 434964.0 -131000.0 -0.96 472917.0 -95500.0 -0.73 -1.1925 -0.9904 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F10 mock treatment 553045.0 -13400.0 -0.1 531902.0 -36500.0 -0.28 -0.2651 -0.9019 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F11 compound treatment 497666.0 -68700.0 -0.5 496125.0 -72300.0 -0.55 -0.7436 -0.999 3012342 CMLD2_000730 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F12 compound treatment 498324.0 -68100.0 -0.5 514026.0 -54400.0 -0.41 -0.6441 -0.9957 3132137 CMLD2_000731 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F13 compound treatment 514922.0 -51500.0 -0.38 485310.0 -83100.0 -0.63 -0.7125 -0.9695 3010880 CMLD2_000732 O[C@@H](COCc1ccco1)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F14 compound treatment 585002.0 18600.0 0.14 496165.0 -72200.0 -0.55 -0.2918 -0.5161 3012343 CMLD2_000733 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F15 compound treatment 568911.0 2510.0 0.02 584762.0 16400.0 0.12 0.1009 0.8029 3132138 CMLD2_000734 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F16 compound treatment 608195.0 41800.0 0.31 578487.0 10100.0 0.08 0.2704 0.8579 3132139 CMLD2_000735 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1Oc6ccc(OC)cc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F17 mock treatment 536303.0 -30100.0 -0.22 602825.0 34400.0 0.26 0.0293 0.0858 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F18 mock treatment 618030.0 51600.0 0.38 440137.0 -128000.0 -0.97 -0.422 -0.4038 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F19 compound treatment 290472.0 -276000.0 -2.02 257809.0 -311000.0 -2.36 -3.0952 -0.997 3012344 CMLD2_000736 CO/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F20 mock treatment 603098.0 36700.0 0.27 494768.0 -73600.0 -0.56 -0.2057 -0.3316 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F21 compound treatment 561461.0 -4940.0 -0.04 584761.0 16400.0 0.12 0.0624 0.4819 3012345 CMLD2_000737 C[C@@H]1CC[C@@H]2N(C[C@@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F22 compound treatment 593219.0 26800.0 0.2 528020.0 -40400.0 -0.31 -0.0782 -0.2147 3132140 CMLD2_000738 CO[C@@H]([C@H](C)/C=C/CC(=O)OCCCc1ccccc1)C2CCCCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F23 mock treatment 616855.0 50500.0 0.37 627134.0 58700.0 0.45 0.5765 0.9955 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 F24 mock treatment 586530.0 20100.0 0.15 470785.0 -97600.0 -0.74 -0.4202 -0.5559 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G01 compound treatment 470041.0 -96400.0 -0.7 541548.0 -26800.0 -0.2 -0.6425 -0.8758 3132141 CMLD2_000739 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@@H](COC(=O)[C@@H](C)NC(=O)C/C=C/[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G02 compound treatment 544328.0 -22100.0 -0.16 529799.0 -38600.0 -0.29 -0.3214 -0.9604 3012346 CMLD2_000740 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G03 mock treatment 462739.0 -104000.0 -0.76 525151.0 -43200.0 -0.33 -0.7683 -0.93 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G04 mock treatment 470242.0 -96200.0 -0.7 620998.0 52600.0 0.4 -0.2146 -0.2654 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G05 compound treatment 486700.0 -79700.0 -0.58 600432.0 32000.0 0.24 -0.24 -0.38 3132142 CMLD2_000741 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G06 compound treatment 514684.0 -51700.0 -0.38 571175.0 2780.0 0.02 -0.2525 -0.6665 3012347 CMLD2_000742 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCCCc4nc(C)c(C)cc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G07 mock treatment 444340.0 -122000.0 -0.89 583723.0 15300.0 0.12 -0.5488 -0.6097 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G08 mock treatment 536581.0 -29800.0 -0.22 601510.0 33100.0 0.25 0.0237 0.0712 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G09 compound treatment 484191.0 -82200.0 -0.6 512419.0 -56000.0 -0.43 -0.7258 -0.9856 3132143 CMLD2_000743 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OCC[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G10 compound treatment 535335.0 -31100.0 -0.23 633546.0 65200.0 0.49 0.1894 0.3477 3132144 CMLD2_000744 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C\3/[C@H](O)[C@H](Oc4ccc(OC)cc34)c5cccc(OC)c5)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G11 compound treatment 571248.0 4850.0 0.04 544273.0 -24100.0 -0.18 -0.1045 -0.5598 3132145 CMLD2_000745 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G12 compound treatment 542701.0 -23700.0 -0.17 516477.0 -51900.0 -0.39 -0.4014 -0.9318 3012401 CMLD2_000746 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H](C)c4cc(no4)c5c(C)cc(C)cc5C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G13 compound treatment 578202.0 11800.0 0.09 626554.0 58200.0 0.44 0.3735 0.8296 3132146 CMLD2_000747 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@@H]7COC[C@H]7O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G14 compound treatment 469531.0 -96900.0 -0.71 522824.0 -45600.0 -0.35 -0.7457 -0.9458 3012403 CMLD2_000748 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G15 compound treatment 663426.0 97000.0 0.71 585706.0 17300.0 0.13 0.5948 0.8241 3132147 CMLD2_000749 CCc1cc2CN(CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G16 compound treatment 615760.0 49400.0 0.36 558042.0 -10400.0 -0.08 0.1997 0.5404 3012404 CMLD2_000750 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G17 compound treatment 512629.0 -53800.0 -0.39 515946.0 -52400.0 -0.4 -0.5598 -1.0 3132148 CMLD2_000751 CO[C@H](/C=N/OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(OC)cc2)c3ccccc3)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G18 compound treatment 526984.0 -39400.0 -0.29 520318.0 -48100.0 -0.37 -0.4621 -0.9931 3132267 CMLD2_000752 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CON=C(C)C)c3ccccc3)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G19 mock treatment 619659.0 53300.0 0.39 594752.0 26400.0 0.2 0.417 0.9522 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G20 mock treatment 559026.0 -7370.0 -0.05 530289.0 -38100.0 -0.29 -0.2428 -0.8246 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G21 compound treatment 560281.0 -6120.0 -0.04 591856.0 23500.0 0.18 0.0944 0.5137 3012405 CMLD2_000753 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G22 compound treatment 345474.0 -221000.0 -1.62 368040.0 -200000.0 -1.52 -2.2187 -0.9996 3132268 CMLD2_000754 CO[C@H]([C@@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)CO)C2CCCCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G23 mock treatment 625832.0 59400.0 0.43 592780.0 24400.0 0.19 0.4384 0.9277 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 G24 mock treatment 569712.0 3310.0 0.02 489406.0 -79000.0 -0.6 -0.4072 -0.678 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H01 compound treatment 531593.0 -34800.0 -0.25 606084.0 37700.0 0.29 0.0225 0.0587 3012408 CMLD2_000755 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H02 compound treatment 475891.0 -90500.0 -0.66 563860.0 -4530.0 -0.03 -0.4924 -0.7429 3132269 CMLD2_000756 C[C@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H03 mock treatment 511383.0 -55000.0 -0.4 621253.0 52900.0 0.4 -5.0E-4 -9.0E-4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H04 mock treatment 488523.0 -77900.0 -0.57 527925.0 -40500.0 -0.31 -0.6201 -0.9581 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H05 compound treatment 476457.0 -89900.0 -0.66 572870.0 4480.0 0.03 -0.441 -0.6696 3132270 CMLD2_000757 CC(=O)OC[C@H]1O[C@H](CCO/N=C/C[C@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C2)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H06 compound treatment 448409.0 -118000.0 -0.86 433448.0 -135000.0 -1.03 -1.335 -0.9963 3012411 CMLD2_000758 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCCCc4nc(C)c(C)cc34 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H07 mock treatment 494994.0 -71400.0 -0.52 506797.0 -61600.0 -0.47 -0.7001 -0.9985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H08 compound treatment 485435.0 -81000.0 -0.59 492376.0 -76000.0 -0.58 -0.827 -0.9999 3132271 CMLD2_000759 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)cc2)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H09 compound treatment 556068.0 -10300.0 -0.08 587213.0 18800.0 0.14 0.0477 0.2949 3132272 CMLD2_000760 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H10 compound treatment 542835.0 -23600.0 -0.17 575725.0 7330.0 0.06 -0.0825 -0.4553 3012412 CMLD2_000761 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C\2/[C@H](O)[C@H](Oc3ccc(OC)cc23)c4cccc(OC)c4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H11 compound treatment 494635.0 -71800.0 -0.52 546386.0 -22000.0 -0.17 -0.4893 -0.8884 3132273 CMLD2_000762 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H12 compound treatment 495057.0 -71300.0 -0.52 496593.0 -71800.0 -0.55 -0.7546 -0.9998 3132274 CMLD2_000763 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](C)[C@H](OCc4ccccc4)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H13 compound treatment 626781.0 60400.0 0.44 531717.0 -36700.0 -0.28 0.1152 0.2207 3012414 CMLD2_000764 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H14 compound treatment 476318.0 -90100.0 -0.66 488841.0 -79600.0 -0.6 -0.8931 -0.9991 3132275 CMLD2_000765 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/OC[C@@H](O)COCc2ccco2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H15 compound treatment 660837.0 94400.0 0.69 680828.0 112000.0 0.85 1.0923 0.9944 3012415 CMLD2_000766 CCc1cc2CN(CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H16 compound treatment 684436.0 118000.0 0.86 603119.0 34700.0 0.26 0.7969 0.8829 3132276 CMLD2_000767 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H17 compound treatment 682327.0 116000.0 0.85 637410.0 69000.0 0.52 0.9702 0.9733 3132277 CMLD2_000768 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](OC)[C@H](C)\C=C\CC(=O)OC)C=C[C@@H]1Oc2ccc(OC)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H18 compound treatment 553595.0 -12800.0 -0.09 567004.0 -1390.0 -0.01 -0.0737 -0.7818 3012416 CMLD2_000769 CCCNC(=O)OC[C@H]1O[C@H](CCON=C(C)C)C=C[C@@H]1Oc2ccc(OC)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H19 mock treatment 575501.0 9100.0 0.07 542524.0 -25900.0 -0.2 -0.0919 -0.4428 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H20 mock treatment 514307.0 -52100.0 -0.38 594446.0 26100.0 0.2 -0.1294 -0.3015 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H21 compound treatment 657561.0 91200.0 0.67 637617.0 69200.0 0.53 0.8433 0.9931 3132278 CMLD2_000770 C[C@@H]1CC[C@@H]2N(C[C@H](COc3ccc(cc3)C(C)(C)C)OC2=O)[C@@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H22 compound treatment 621514.0 55100.0 0.4 662035.0 93600.0 0.71 0.788 0.9638 3012418 CMLD2_000771 CO[C@H]1[C@H](C)/C(=C\CCOCC#CC)/c2ccccc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H23 mock treatment 623557.0 57200.0 0.42 632896.0 64500.0 0.49 0.6421 0.9969 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 H24 mock treatment 519104.0 -47300.0 -0.35 530636.0 -37800.0 -0.29 -0.4474 -0.9957 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I01 compound treatment 566556.0 159.0 0.0 534979.0 -33400.0 -0.25 -0.1787 -0.7039 3132279 CMLD2_000772 CO[C@H]1COC(=O)C/C=C/[C@@H](C)[C@@H](COC(=O)CCC[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I02 compound treatment 509530.0 -56900.0 -0.42 528216.0 -40200.0 -0.31 -0.5099 -0.9884 3012419 CMLD2_000773 C[C@@H]/1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C\C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I03 compound treatment 525509.0 -40900.0 -0.3 580934.0 12500.0 0.1 -0.1441 -0.4591 3132280 CMLD2_000774 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(OC)cc4)c5ccccc5)c6ccccc6)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I04 compound treatment 536894.0 -29500.0 -0.22 516152.0 -52200.0 -0.4 -0.4332 -0.959 3132281 CMLD2_000775 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I05 mock treatment 450762.0 -116000.0 -0.85 623067.0 54700.0 0.42 -0.3043 -0.323 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I06 mock treatment 504284.0 -62100.0 -0.45 582031.0 13600.0 0.1 -0.2479 -0.5322 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I07 compound treatment 545670.0 -20700.0 -0.15 598129.0 29700.0 0.23 0.0526 0.1932 3012420 CMLD2_000776 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I08 compound treatment 465916.0 -100000.0 -0.73 584931.0 16500.0 0.13 -0.4308 -0.5778 3132282 CMLD2_000777 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)cc2)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I09 compound treatment 506720.0 -59700.0 -0.44 638247.0 69900.0 0.53 0.0666 0.097 3012421 CMLD2_000778 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC(C)CN2CCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I10 compound treatment 472212.0 -94200.0 -0.69 520567.0 -47800.0 -0.36 -0.744 -0.9553 3132283 CMLD2_000779 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I11 compound treatment 592426.0 26000.0 0.19 663285.0 94900.0 0.72 0.6443 0.8642 3012422 CMLD2_000780 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@H]4O[C@@H](C=C[C@@H]4Oc5ccc(OC)cc5)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I12 compound treatment 553247.0 -13200.0 -0.1 553980.0 -14400.0 -0.11 -0.1454 -0.9979 3012473 CMLD2_000781 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]4OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I13 compound treatment 475195.0 -91200.0 -0.67 491146.0 -77200.0 -0.59 -0.8866 -0.998 3132284 CMLD2_000782 C[C@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cc(no6)c7c(C)cc(C)cc7C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I14 compound treatment 574130.0 7730.0 0.06 558518.0 -9870.0 -0.08 -0.0131 -0.139 3012475 CMLD2_000783 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I15 compound treatment 636428.0 70000.0 0.51 226940.0 -341000.0 -2.59 -1.4721 -0.5567 3132285 CMLD2_000784 CCc1cc2CN(CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I16 compound treatment 620147.0 53700.0 0.39 645147.0 76800.0 0.58 0.6903 0.9816 3012476 CMLD2_000785 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I17 compound treatment 573563.0 7170.0 0.05 642748.0 74400.0 0.56 0.4365 0.7694 3132408 CMLD2_000786 CO[C@H](/C=N/OCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I18 compound treatment 554925.0 -11500.0 -0.08 579360.0 11000.0 0.08 -4.0E-4 -0.0035 3012477 CMLD2_000787 CC(=NOCC[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I19 compound treatment 588139.0 21700.0 0.16 536494.0 -31900.0 -0.24 -0.0589 -0.2033 3132409 CMLD2_000788 CO/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I20 mock treatment 557710.0 -8690.0 -0.06 619019.0 50600.0 0.38 0.227 0.5824 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I21 mock treatment 659962.0 93600.0 0.68 475806.0 -92600.0 -0.7 -0.0135 -0.0138 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I22 mock treatment 525958.0 -40400.0 -0.3 639410.0 71000.0 0.54 0.1724 0.2802 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I23 mock treatment 544544.0 -21900.0 -0.16 634823.0 66400.0 0.5 0.2438 0.4606 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 I24 mock treatment 544975.0 -21400.0 -0.16 566605.0 -1790.0 -0.01 -0.1204 -0.7655 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J01 compound treatment 544876.0 -21500.0 -0.16 583415.0 15000.0 0.11 -0.0306 -0.1574 3132410 CMLD2_000789 CO[C@@H]1COC(=O)[C@H](C)NC(=O)C/C=C/[C@@H](OC)[C@H](C)COC(=O)CCC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J02 compound treatment 541405.0 -25000.0 -0.18 524645.0 -43700.0 -0.33 -0.3642 -0.9603 3012478 CMLD2_000790 CO[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J03 compound treatment 556828.0 -9570.0 -0.07 538787.0 -29600.0 -0.22 -0.2085 -0.8853 3132411 CMLD2_000791 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(OC)cc3)c4ccccc4)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J04 compound treatment 518881.0 -47500.0 -0.35 656717.0 88300.0 0.67 0.2287 0.3027 3132412 CMLD2_000792 CC(=O)OC[C@H]1O[C@H](CCO/N=C(\C)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J05 mock treatment 452984.0 -113000.0 -0.83 503374.0 -65000.0 -0.49 -0.9357 -0.9693 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J06 mock treatment 438228.0 -128000.0 -0.94 500816.0 -67600.0 -0.51 -1.0258 -0.9599 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J07 compound treatment 451827.0 -115000.0 -0.84 586410.0 18000.0 0.14 -0.4957 -0.5839 3012479 CMLD2_000793 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J08 compound treatment 474538.0 -91900.0 -0.67 506645.0 -61700.0 -0.47 -0.8067 -0.9846 3012480 CMLD2_000794 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](O)COCc3ccco3)cc2)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J09 compound treatment 634126.0 67700.0 0.5 522540.0 -45900.0 -0.35 0.1039 0.1716 3132413 CMLD2_000795 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J10 compound treatment 542474.0 -23900.0 -0.17 593596.0 25200.0 0.19 0.0117 0.045 3132414 CMLD2_000796 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCCc5nc(C)c(C)cc45)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J11 compound treatment 599696.0 33300.0 0.24 414990.0 -153000.0 -1.17 -0.6518 -0.5475 3132415 CMLD2_000797 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\C[C@@H](O)[C@@H](O)[C@@H]3[C@H]4[C@@H](CC[C@H]32)C(=O)N(CC)C4=O)C=C[C@@H]1Oc5ccc(OC)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J12 compound treatment 540182.0 -26200.0 -0.19 632912.0 64500.0 0.49 0.211 0.4009 3012481 CMLD2_000798 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/O[C@H](C)c4cn(nn4)[C@H](CO)Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J13 compound treatment 457542.0 -109000.0 -0.8 429949.0 -138000.0 -1.05 -1.3066 -0.9906 3132416 CMLD2_000799 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J14 compound treatment 607033.0 40600.0 0.3 508442.0 -60000.0 -0.46 -0.1119 -0.2058 3012482 CMLD2_000800 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J15 compound treatment 672574.0 106000.0 0.78 564057.0 -4340.0 -0.03 0.5258 0.6765 3132417 CMLD2_000801 CCc1cc2CN(CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J16 compound treatment 755164.0 189000.0 1.38 689182.0 121000.0 0.92 1.625 0.9803 3012484 CMLD2_000802 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCN3CCc4nc(c5ccccc5)c(cc4C3)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J17 compound treatment 576432.0 10000.0 0.07 553675.0 -14700.0 -0.11 -0.0272 -0.2031 3132418 CMLD2_000803 CO[C@H](/C=N/OC(C)CN1CCCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J18 compound treatment 597006.0 30600.0 0.22 535584.0 -32800.0 -0.25 -0.018 -0.0536 3012486 CMLD2_000804 CC(CN1CCCCc2nc(C)c(C)cc12)ON=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J19 compound treatment 581235.0 14800.0 0.11 659172.0 90800.0 0.69 0.5644 0.8084 3132419 CMLD2_000805 CO/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J20 mock treatment 676616.0 110000.0 0.81 587054.0 18700.0 0.14 0.6702 0.8189 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J21 mock treatment 723317.0 157000.0 1.15 651997.0 83600.0 0.64 1.2606 0.9611 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J22 mock treatment 559407.0 -6990.0 -0.05 585709.0 17300.0 0.13 0.0569 0.403 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J23 mock treatment 694762.0 128000.0 0.94 588206.0 19800.0 0.15 0.7702 0.8101 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 J24 mock treatment 599450.0 33100.0 0.24 567289.0 -1100.0 -0.01 0.165 0.6822 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K01 compound treatment 609460.0 43100.0 0.31 584193.0 15800.0 0.12 0.3076 0.9126 3132420 CMLD2_000806 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K02 compound treatment 501027.0 -65400.0 -0.48 538042.0 -30400.0 -0.23 -0.5011 -0.9441 3012487 CMLD2_000807 C[C@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](Cc3ccccc3)NC1=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K03 compound treatment 531540.0 -34900.0 -0.25 583260.0 14900.0 0.11 -0.1004 -0.36 3132421 CMLD2_000808 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OCC[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3)/C)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K04 compound treatment 520221.0 -46200.0 -0.34 623531.0 55100.0 0.42 0.0574 0.1067 3132422 CMLD2_000809 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K05 compound treatment 475450.0 -90900.0 -0.67 604520.0 36100.0 0.27 -0.2762 -0.3839 3012488 CMLD2_000810 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K06 compound treatment 496081.0 -70300.0 -0.51 563670.0 -4720.0 -0.04 -0.389 -0.7546 3132423 CMLD2_000811 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K07 mock treatment 459157.0 -107000.0 -0.78 645071.0 76700.0 0.58 -0.1427 -0.146 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K08 mock treatment 516113.0 -50300.0 -0.37 593938.0 25500.0 0.19 -0.1228 -0.2953 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K09 compound treatment 574765.0 8370.0 0.06 635734.0 67300.0 0.51 0.405 0.7861 3132424 CMLD2_000812 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K10 compound treatment 642797.0 76400.0 0.56 639652.0 71300.0 0.54 0.7779 0.9999 3011824 CMLD2_000813 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC(C)CN4CCCc5nc(C)c(C)cc45)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K11 compound treatment 507370.0 -59000.0 -0.43 570076.0 1680.0 0.01 -0.2962 -0.6859 3132425 CMLD2_000814 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OCC[C@H]4O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K12 compound treatment 523725.0 -42700.0 -0.31 592262.0 23900.0 0.18 -0.0924 -0.2561 3132426 CMLD2_000815 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O)c8ccccc8)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K13 compound treatment 633018.0 66600.0 0.49 635832.0 67400.0 0.51 0.7068 0.9997 3011825 CMLD2_000816 CC(=O)OC[C@H]1O[C@@H](O/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K14 compound treatment 596476.0 30100.0 0.22 569814.0 1420.0 0.01 0.1632 0.7409 3132547 CMLD2_000817 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H](C)c2cc(no2)c3c(C)cc(C)cc3C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K15 mock treatment 592807.0 26400.0 0.19 668685.0 100000.0 0.76 0.6753 0.8592 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K16 mock treatment 624839.0 58400.0 0.43 639767.0 71400.0 0.54 0.6856 0.9931 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K17 compound treatment 525491.0 -40900.0 -0.3 631061.0 62700.0 0.48 0.1251 0.2225 3011826 CMLD2_000818 CO[C@H](/C=N/OC(C)CN1CCCc2nc(C)c(C)cc12)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K18 compound treatment 587522.0 21100.0 0.15 598603.0 30200.0 0.23 0.2715 0.9814 3132548 CMLD2_000819 CC(CN1CCCc2nc(C)c(C)cc12)ON=C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K19 compound treatment 668485.0 102000.0 0.75 642587.0 74200.0 0.56 0.9265 0.9904 3011827 CMLD2_000820 CO/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K20 compound treatment 610510.0 44100.0 0.32 621102.0 52700.0 0.4 0.5113 0.9943 3131977 CMLD2_000821 COC(=O)C1=C2N(Cc3ccccc3)C(=C([C@H](N2C(=O)[C@@](O)(C1)C(=O)OC)c4ccccc4)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K21 compound treatment 636846.0 70400.0 0.52 654620.0 86200.0 0.66 0.8275 0.9929 3132549 CMLD2_000822 C[C@@H]1CC[C@@H]2N(C[C@H](Cc3ccccc3)OC2=O)[C@H]1c4ccc(Br)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K22 compound treatment 588103.0 21700.0 0.16 642941.0 74500.0 0.57 0.5127 0.8717 3132550 CMLD2_000823 CCO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)/C=C/CC(=O)OC)c1cc(OC)cc([N+](=O)[O-])c1OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K23 mock treatment 555140.0 -11300.0 -0.08 487848.0 -80500.0 -0.61 -0.4909 -0.7951 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 K24 mock treatment 505141.0 -61300.0 -0.45 530423.0 -38000.0 -0.29 -0.5207 -0.9773 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L01 compound treatment 586603.0 20200.0 0.15 587125.0 18700.0 0.14 0.2051 0.9998 3011828 CMLD2_000824 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L02 compound treatment 350442.0 -216000.0 -1.58 496394.0 -72000.0 -0.55 -1.5035 -0.8996 3132551 CMLD2_000825 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)[C@H](COCc3ccccc3)NC(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L03 compound treatment 499484.0 -66900.0 -0.49 669404.0 101000.0 0.77 0.1966 0.216 3011829 CMLD2_000826 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L04 compound treatment 515954.0 -50400.0 -0.37 666674.0 98300.0 0.75 0.2671 0.3207 3132552 CMLD2_000827 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C(\C)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L05 compound treatment 400123.0 -166000.0 -1.22 578367.0 9970.0 0.08 -0.8062 -0.6618 3132553 CMLD2_000828 CC(CN1CCCc2nc(C)c(C)cc12)O/N=C/C[C@H]3O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L06 compound treatment 482068.0 -84300.0 -0.62 568230.0 -162.0 0.0 -0.437 -0.7085 3011830 CMLD2_000829 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L07 mock treatment 560513.0 -5880.0 -0.04 673016.0 105000.0 0.79 0.5316 0.6678 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L08 mock treatment 571600.0 5200.0 0.04 567848.0 -544.0 0.0 0.024 0.6266 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L09 compound treatment 547355.0 -19000.0 -0.14 642500.0 74100.0 0.56 0.2996 0.5166 3132554 CMLD2_000830 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\OC[C@@H](O)COCc2ccco2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L10 compound treatment 435172.0 -131000.0 -0.96 417884.0 -151000.0 -1.14 -1.4871 -0.9962 3011831 CMLD2_000831 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L11 compound treatment 604628.0 38200.0 0.28 625264.0 56900.0 0.43 0.5032 0.9778 3132555 CMLD2_000832 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCCc5nc(C)c(C)cc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L12 compound treatment 500391.0 -66000.0 -0.48 528667.0 -39700.0 -0.3 -0.5547 -0.9744 3132556 CMLD2_000833 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1Oc7ccc(OC)cc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L13 compound treatment 651628.0 85200.0 0.62 591858.0 23500.0 0.18 0.5668 0.8743 3011832 CMLD2_000834 C[C@@H](O/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O)c6cn(nn6)[C@H](CO)Cc7ccccc7 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L14 compound treatment 431413.0 -135000.0 -0.99 575309.0 6920.0 0.05 -0.6609 -0.6685 3132557 CMLD2_000835 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L15 mock treatment 635489.0 69100.0 0.51 579628.0 11200.0 0.09 0.4176 0.815 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L16 mock treatment 594975.0 28600.0 0.21 588282.0 19900.0 0.15 0.2546 0.9873 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L17 compound treatment 532602.0 -33800.0 -0.25 602191.0 33800.0 0.26 0.0068 0.0191 3132558 CMLD2_000836 CO[C@H](/C=N/OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L18 compound treatment 595682.0 29300.0 0.21 566127.0 -2270.0 -0.02 0.1393 0.6482 3011833 CMLD2_000837 CC(=NOC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L19 compound treatment 561420.0 -4980.0 -0.04 518086.0 -50300.0 -0.38 -0.296 -0.771 3011834 CMLD2_000838 CO/N=C/c1ccc(cc1)C(=O)N2[C@@H](CC[C@H](C)[C@H]2c3ccc(C)cc3)C(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L20 compound treatment 612380.0 46000.0 0.34 568330.0 -62.4 0.0 0.2374 0.7061 3132559 CMLD2_000839 CCC(=O)[C@]1(O)[C@H]2CCOC(=O)C2=C3N(Cc4ccccc4)C(=C([C@H](N3C1=O)c5ccccc5)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L21 compound treatment 570243.0 3850.0 0.03 656447.0 88100.0 0.67 0.4929 0.7362 3132529 CMLD2_000840 CCCC[C@@H]1CN2[C@@H]([C@@H](C)CC[C@H]2C(=O)O1)c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L22 compound treatment 564001.0 -2400.0 -0.02 622532.0 54100.0 0.41 0.2784 0.6764 3011835 CMLD2_000841 CO[C@@H]([C@H](C)[C@@H](OC)[C@H](C)C(=O)C)[C@@H](C)[C@H](OC)c1ccccc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L23 mock treatment 612514.0 46100.0 0.34 678233.0 110000.0 0.83 0.8285 0.9206 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 L24 mock treatment 608292.0 41900.0 0.31 569225.0 833.0 0.01 0.2211 0.7216 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M01 compound treatment 575505.0 9110.0 0.07 540755.0 -27600.0 -0.21 -0.1014 -0.4602 3132560 CMLD2_000842 CO[C@@H]1COC(=O)C/C=C/[C@@H](C)[C@H]2O[C@H](COC(=O)CCC[C@H]1C)[C@@H](O)C=C2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M02 compound treatment 579640.0 13200.0 0.1 456643.0 -112000.0 -0.85 -0.5318 -0.6224 3011836 CMLD2_000843 C[C@H]/1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C\C=C1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M03 compound treatment 634810.0 68400.0 0.5 673679.0 105000.0 0.8 0.9193 0.9745 3132561 CMLD2_000844 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC(C)CN3CCCc4nc(C)c(C)cc34)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M04 compound treatment 495102.0 -71300.0 -0.52 630902.0 62500.0 0.47 -0.0329 -0.0466 3132562 CMLD2_000845 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M05 compound treatment 524191.0 -42200.0 -0.31 574000.0 5610.0 0.04 -0.1881 -0.6038 3011870 CMLD2_000846 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)[C@H]2O[C@@H]3OC(C)(C)O[C@@H]3[C@H]2O)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M06 compound treatment 496908.0 -69500.0 -0.51 681947.0 114000.0 0.86 0.2506 0.2503 3132563 CMLD2_000847 C[C@@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M07 compound treatment 519452.0 -46900.0 -0.34 658746.0 90400.0 0.69 0.2426 0.3161 3011871 CMLD2_000848 C[C@@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@@H]4COC[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M08 compound treatment 496639.0 -69800.0 -0.51 545898.0 -22500.0 -0.17 -0.4816 -0.8951 3132564 CMLD2_000849 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)cc2)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M09 mock treatment 521027.0 -45400.0 -0.33 584649.0 16300.0 0.12 -0.1473 -0.416 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M10 mock treatment 495961.0 -70400.0 -0.52 572545.0 4150.0 0.03 -0.3419 -0.6626 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M11 compound treatment 510668.0 -55700.0 -0.41 569300.0 908.0 0.01 -0.2833 -0.695 3011872 CMLD2_000850 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC(C)CN4CCCc5nc(C)c(C)cc45 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M12 compound treatment 595252.0 28900.0 0.21 587905.0 19500.0 0.15 0.254 0.9851 3132565 CMLD2_000851 CC(=O)OC[C@H]1O[C@H](CCO/N=C/2\[C@H]3O[C@H]3[C@@H](O)[C@H]4[C@@H]2CCn5n4c(=O)n(c6ccccc6)c5=O)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M13 mock treatment 563166.0 -3230.0 -0.02 576768.0 8380.0 0.06 0.0283 0.4167 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M14 mock treatment 565309.0 -1090.0 -0.01 705682.0 137000.0 1.04 0.7319 0.7017 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M15 compound treatment 689072.0 123000.0 0.9 775396.0 207000.0 1.57 1.7463 0.9646 3132566 CMLD2_000852 CCc1cc2CN(CC/C(=N/O[C@H](C)c3cn(nn3)[C@@H]4COC[C@H]4O)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M16 compound treatment 791976.0 226000.0 1.65 781051.0 213000.0 1.62 2.3088 0.9999 3011873 CMLD2_000853 C/C(=N\O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M17 compound treatment 580721.0 14300.0 0.1 670624.0 102000.0 0.78 0.6232 0.7953 3130490 CMLD2_000854 CO[C@H](/C=N/O[C@H]1C=C[C@@H](CC=C)O[C@@H]1CO)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M18 compound treatment 545670.0 -20700.0 -0.15 660774.0 92400.0 0.7 0.3891 0.5419 3011875 CMLD2_000855 CC(=NOC1C=C[C@@H](CC=C)O[C@@H]1CO)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M19 compound treatment 562815.0 -3580.0 -0.03 617200.0 48800.0 0.37 0.2437 0.6555 3130491 CMLD2_000856 CO/N=C/[C@@H](NS(=O)(=O)c1ccc(C)cc1)[C@H](C)\C=C\CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M20 compound treatment 674180.0 108000.0 0.79 699598.0 131000.0 1.0 1.2622 0.9932 3132404 CMLD2_000857 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C([C@H](c4ccccc4)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5)C(=O)c6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M21 compound treatment 674803.0 108000.0 0.79 565950.0 -2440.0 -0.02 0.5475 0.6904 3011876 CMLD2_000858 C[C@H]1CC[C@@H]2N(C[C@@H](CO)OC2=O)[C@@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M22 compound treatment 626245.0 59800.0 0.44 695096.0 127000.0 0.96 0.9901 0.9364 3130492 CMLD2_000859 CO[C@@H]([C@H](C)/C=C/CC(=O)OC)c1ccccc1Br 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M23 mock treatment 633065.0 66700.0 0.49 654557.0 86200.0 0.65 0.8076 0.9895 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 M24 mock treatment 558739.0 -7660.0 -0.06 502000.0 -66400.0 -0.5 -0.3962 -0.7808 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N01 compound treatment 620496.0 54100.0 0.4 623634.0 55200.0 0.42 0.5765 0.9996 3130493 CMLD2_000860 CO[C@H]1COC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](C)COC(=O)CCC[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N02 compound treatment 528163.0 -38200.0 -0.28 592275.0 23900.0 0.18 -0.0694 -0.2083 3011877 CMLD2_000861 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)[C@H]2CCCN2C(=O)C/C=C/[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N03 compound treatment 521818.0 -44600.0 -0.33 659734.0 91300.0 0.69 0.2601 0.3393 3130494 CMLD2_000862 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)[C@H]3O[C@@H]4OC(C)(C)O[C@@H]4[C@H]3O)/C)c5ccccc5)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N04 compound treatment 490467.0 -75900.0 -0.56 646383.0 78000.0 0.59 0.0263 0.0324 3130495 CMLD2_000863 C/C(=N\OC[C@@H](O)[C@H]1O[C@@H]2OC(C)(C)O[C@@H]2[C@H]1O)/CCC(=O)OC[C@H]3O[C@@H](C=C[C@@H]3Oc4ccc(C)cc4)C#Cc5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N05 compound treatment 534019.0 -32400.0 -0.24 664253.0 95900.0 0.73 0.3475 0.4538 3011878 CMLD2_000864 CC(=O)OC[C@H]1O[C@H](C/C=N/O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N06 compound treatment 483569.0 -82800.0 -0.61 651165.0 82800.0 0.63 0.0163 0.0187 3130496 CMLD2_000865 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N07 compound treatment 491903.0 -74500.0 -0.54 614726.0 46300.0 0.35 -0.1363 -0.2102 3011879 CMLD2_000866 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cn(nn3)[C@H](CO)Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N08 compound treatment 555811.0 -10600.0 -0.08 437350.0 -131000.0 -1.0 -0.7587 -0.7598 3130497 CMLD2_000867 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)cc2)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N09 mock treatment 555019.0 -11400.0 -0.08 589452.0 21100.0 0.16 0.0543 0.3011 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N10 mock treatment 596524.0 30100.0 0.22 602747.0 34400.0 0.26 0.3403 0.9965 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N11 compound treatment 548116.0 -18300.0 -0.13 638499.0 70100.0 0.53 0.2821 0.5137 3011881 CMLD2_000868 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC[C@@H](O)[C@H]4O[C@@H]5OC(C)(C)O[C@@H]5[C@H]4O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N12 compound treatment 528881.0 -37500.0 -0.27 661242.0 92800.0 0.71 0.3048 0.4027 3130498 CMLD2_000869 CC(CN1CCCCc2nc(C)c(C)cc12)O/N=C/3\[C@H]4O[C@H]4[C@@H](O)[C@H]5[C@@H]3CCn6n5c(=O)n(c7ccccc7)c6=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N13 mock treatment 549279.0 -17100.0 -0.13 646384.0 78000.0 0.59 0.3304 0.5457 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N14 mock treatment 528636.0 -37800.0 -0.28 614297.0 45900.0 0.35 0.0513 0.1154 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N15 compound treatment 728714.0 162000.0 1.19 746853.0 178000.0 1.36 1.798 0.9978 3130499 CMLD2_000870 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cn(nn3)[C@H](CO)Cc4ccccc4)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N16 compound treatment 740253.0 174000.0 1.27 774422.0 206000.0 1.57 2.0058 0.9947 3011882 CMLD2_000871 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCN2CCc3nc(c4ccccc4)c(cc3C2)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N17 compound treatment 551952.0 -14400.0 -0.11 663413.0 95000.0 0.72 0.4357 0.5973 3130500 CMLD2_000872 CO[C@H](/C=N/OC[C@@H](O)COCc1ccco1)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N18 compound treatment 688695.0 122000.0 0.89 604794.0 36400.0 0.28 0.828 0.8844 3011884 CMLD2_000873 CC(=NOC[C@@H](O)COCc1ccco1)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N19 compound treatment 531323.0 -35100.0 -0.26 463910.0 -104000.0 -0.79 -0.7426 -0.8903 3130501 CMLD2_000874 CO/N=C\1/[C@H](O)[C@H](Oc2ccc(OC)cc12)c3cccc(OC)c3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N20 compound treatment 719569.0 153000.0 1.12 666969.0 98600.0 0.75 1.3216 0.9808 3131849 CMLD2_000875 COC(=O)[C@H]1[C@@H](C(=O)OC)[C@]23O[C@]1(C(=O)OC)C(=O)N3[C@@H](C(=C(C)N2Cc4ccccc4)C(=O)OC)c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N21 compound treatment 717309.0 151000.0 1.1 670812.0 102000.0 0.78 1.3306 0.9854 3011885 CMLD2_000876 C[C@@H]1CC[C@@H]2N(C[C@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N22 compound treatment 771690.0 205000.0 1.5 596174.0 27800.0 0.21 1.2108 0.7987 3130502 CMLD2_000877 CO[C@@H]([C@H](C)[C@H](OCc1cccc(Br)c1)[C@@H](C)/C=C/CC(=O)OC)C2CCCCC2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N23 mock treatment 688031.0 122000.0 0.89 631987.0 63600.0 0.48 0.9706 0.9589 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 N24 mock treatment 585576.0 19200.0 0.14 570020.0 1630.0 0.01 0.1079 0.7665 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O01 compound treatment 633013.0 66600.0 0.49 593853.0 25500.0 0.19 0.4812 0.9181 3011886 CMLD2_000878 CO[C@@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)CCC[C@@H]1C)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O02 compound treatment 484296.0 -82100.0 -0.6 578819.0 10400.0 0.08 -0.3685 -0.6086 3130503 CMLD2_000879 CO[C@H]1COC(=O)[C@H](C)NC(=O)[C@@H](C)COC(=O)C/C=C/[C@@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O03 compound treatment 482372.0 -84000.0 -0.61 574207.0 5810.0 0.04 -0.4033 -0.6546 3130504 CMLD2_000880 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/O[C@H]3C=C[C@@H](CC=C)O[C@@H]3CO)/C)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O04 compound treatment 503355.0 -63000.0 -0.46 545229.0 -23200.0 -0.18 -0.4504 -0.9128 3130505 CMLD2_000881 C/C(=N\OC[C@@H](O)COCc1ccco1)/CCC(=O)OC[C@H]2O[C@@H](C=C[C@@H]2Oc3ccc(C)cc3)C#Cc4ccccc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O05 compound treatment 522439.0 -44000.0 -0.32 674180.0 106000.0 0.8 0.3409 0.3939 3130506 CMLD2_000882 CC(=O)OC[C@H]1O[C@H](C/C=N/OC[C@@H](O)COCc2ccco2)C=C[C@@H]1OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O06 compound treatment 539460.0 -26900.0 -0.2 621967.0 53600.0 0.41 0.1485 0.3284 3011921 CMLD2_000883 C[C@H](O/N=C(\C)/CCN1CCCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O07 compound treatment 662005.0 95600.0 0.7 740136.0 172000.0 1.3 1.417 0.9573 3130507 CMLD2_000884 C[C@H](O/N=C(\C)/CCN1CCCc2nc(C)c(C)cc12)c3cc(no3)c4c(C)cc(C)cc4C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O08 compound treatment 572682.0 6280.0 0.05 818368.0 250000.0 1.9 1.3753 0.724 3130508 CMLD2_000885 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)cc2)c5ccc(C)cc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O09 compound treatment 604557.0 38200.0 0.28 746753.0 178000.0 1.35 1.1554 0.8352 3011922 CMLD2_000886 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@H](C)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O10 compound treatment 581201.0 14800.0 0.11 726322.0 158000.0 1.2 0.9249 0.7678 3130509 CMLD2_000887 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\O[C@H]4C=C[C@@H](CC=C)O[C@@H]4CO)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O11 mock treatment 598129.0 31700.0 0.23 742373.0 174000.0 1.32 1.0987 0.8187 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O12 mock treatment 602633.0 36200.0 0.26 707859.0 139000.0 1.06 0.9366 0.8575 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O13 compound treatment 692784.0 126000.0 0.92 763631.0 195000.0 1.48 1.7023 0.9741 3011925 CMLD2_000888 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO/N=C/[C@@H](C)[C@H](OCc3ccccc3)C(C)C)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O14 compound treatment 615109.0 48700.0 0.36 609138.0 40700.0 0.31 0.4708 0.9975 3130636 CMLD2_000889 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@@H]2O[C@H](COC(=O)C)[C@@H](OC(=O)C)[C@H](OC(=O)C)[C@H]2OC(=O)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O15 compound treatment 604573.0 38200.0 0.28 807146.0 239000.0 1.81 1.4799 0.8065 3011927 CMLD2_000890 CCc1cc2CN(CC/C(=N/O[C@@H](C)c3cc(no3)c4c(C)cc(C)cc4C)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O16 compound treatment 591920.0 25500.0 0.19 768047.0 200000.0 1.52 1.2045 0.7882 3130637 CMLD2_000891 C[C@@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@@H]6COC[C@H]6O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O17 compound treatment 524645.0 -41800.0 -0.31 643028.0 74600.0 0.57 0.185 0.2873 3130638 CMLD2_000892 CO[C@H](/C=N/O[C@H](C)c1cn(nn1)[C@@H]2COC[C@H]2O)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O18 compound treatment 621802.0 55400.0 0.41 667314.0 98900.0 0.75 0.8179 0.958 3011928 CMLD2_000893 C[C@@H](ON=C(C)C)c1cn(nn1)[C@@H]2COC[C@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O19 compound treatment 579277.0 12900.0 0.09 551805.0 -16600.0 -0.13 -0.0225 -0.143 3130639 CMLD2_000894 CCN1C(=O)[C@@H]2CC[C@@H]/3[C@@H]([C@@H]2C1=O)[C@H](O)[C@H](O)C\C3=N/OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O20 compound treatment 610134.0 43700.0 0.32 644282.0 75900.0 0.58 0.6338 0.9614 3011929 CMLD2_000895 CCN1C(=C([C@H](N2C(=O)[C@@](O)(CC(=C12)C(=O)C)C(=O)OC)c3ccccc3)C(=O)OC)C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O21 compound treatment 687511.0 121000.0 0.89 653609.0 85200.0 0.65 1.0841 0.9881 3130640 CMLD2_000896 C[C@@H]1CC[C@@H]2N(C[C@@H](COC(=O)C(=C)C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O22 mock treatment 677487.0 111000.0 0.81 653396.0 85000.0 0.65 1.0311 0.9935 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O23 mock treatment 663124.0 96700.0 0.71 584468.0 16100.0 0.12 0.5865 0.8171 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 O24 mock treatment 666369.0 100000.0 0.73 574123.0 5730.0 0.04 0.5478 0.7479 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P01 compound treatment 656323.0 89900.0 0.66 594474.0 26100.0 0.2 0.6051 0.881 3011930 CMLD2_000897 CO[C@H]1COC(=O)C/C=C/[C@H](C)[C@H](COC(=O)C/C=C/[C@@H]1C)NS(=O)(=O)c2ccc(C)cc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P02 compound treatment 608860.0 42500.0 0.31 636523.0 68100.0 0.52 0.5856 0.9701 3130641 CMLD2_000898 CO[C@@H]1COC(=O)[C@@H]2CCCN2C(=O)[C@@H](C)COC(=O)CCC[C@H]1C 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P03 compound treatment 541987.0 -24400.0 -0.18 703446.0 135000.0 1.03 0.5992 0.5754 3130642 CMLD2_000899 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2COC(=O)CC/C(=N/OC[C@@H](O)COCc3ccco3)/C)c4ccccc4)cc1 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P04 compound treatment 595406.0 29000.0 0.21 665000.0 96600.0 0.73 0.669 0.8757 3130643 CMLD2_000900 C[C@@H](O/N=C(\C)/CCC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C)cc2)C#Cc3ccccc3)c4cn(nn4)[C@@H]5COC[C@H]5O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P05 compound treatment 541885.0 -24500.0 -0.18 709503.0 141000.0 1.07 0.6313 0.5808 3011932 CMLD2_000901 C[C@@H](O/N=C/C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1)c2cn(nn2)[C@@H]3COC[C@H]3O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P06 compound treatment 617799.0 51400.0 0.38 777707.0 209000.0 1.59 1.3902 0.8508 3130644 CMLD2_000902 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P07 compound treatment 604314.0 37900.0 0.28 751775.0 183000.0 1.39 1.1812 0.8315 3011933 CMLD2_000903 CC(C)[C@@H](OCc1ccccc1)[C@H](C)CO/N=C(\C)/CCN2CCCc3nc(C)c(C)cc23 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P08 compound treatment 758433.0 192000.0 1.4 779435.0 211000.0 1.6 2.1267 0.9978 3130645 CMLD2_000904 COC(=O)[C@@H]1CC[C@H](C)[C@H](N1C(=O)c2ccc(/C=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)cc2)c4ccc(C)cc4 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P09 compound treatment 644266.0 77900.0 0.57 745208.0 177000.0 1.34 1.3525 0.927 3011935 CMLD2_000905 COC(=O)C/C=C/[C@@H](C)[C@H](NS(=O)(=O)c1ccc(C)cc1)\C=N\O[C@@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P10 compound treatment 629629.0 63200.0 0.46 660055.0 91700.0 0.7 0.8194 0.9802 3130646 CMLD2_000906 COc1cccc(c1)[C@H]2Oc3ccc(OC)cc3/C(=N\OC[C@@H](O)COCc4ccco4)/[C@@H]2O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P11 mock treatment 786631.0 220000.0 1.61 684642.0 116000.0 0.88 1.7633 0.96 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P12 mock treatment 688726.0 122000.0 0.89 769933.0 202000.0 1.53 1.7152 0.9673 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P13 compound treatment 762433.0 196000.0 1.43 700097.0 132000.0 1.0 1.7212 0.9845 3130647 CMLD2_000907 CCCNC(=O)OC[C@H]1O[C@H](CCO/N=C/[C@@H](C)[C@H](OCc2ccccc2)C(C)C)C=C[C@@H]1Oc3ccc(OC)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P14 compound treatment 577430.0 11000.0 0.08 601593.0 33200.0 0.25 0.2354 0.8889 3011936 CMLD2_000908 CC(C)[C@@H](OCc1ccccc1)[C@H](C)/C=N/O[C@H](C)c2cn(nn2)[C@H](CO)Cc3ccccc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P15 compound treatment 725667.0 159000.0 1.16 680576.0 112000.0 0.85 1.4262 0.9882 3130648 CMLD2_000909 CCc1cc2CN(CC/C(=N/OC[C@@H](C)[C@H](OCc3ccccc3)C(C)C)/C)CCc2nc1CC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P16 compound treatment 719592.0 153000.0 1.12 681284.0 113000.0 0.86 1.3986 0.9913 3130649 CMLD2_000910 C[C@H](O/N=C(\C)/CCN1CCc2nc(c3ccccc3)c(cc2C1)c4ccccc4)c5cn(nn5)[C@H](CO)Cc6ccccc6 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P17 compound treatment 643222.0 76800.0 0.56 616651.0 48300.0 0.37 0.6565 0.9786 3011937 CMLD2_000911 CO[C@H](/C=N/O[C@@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)[C@H](C)/C=C/CC(=O)OC 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P18 compound treatment 725593.0 159000.0 1.16 632169.0 63800.0 0.48 1.1658 0.9245 3130650 CMLD2_000912 C[C@H](ON=C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P19 compound treatment 679534.0 113000.0 0.83 597011.0 28600.0 0.22 0.7388 0.8636 3011939 CMLD2_000913 CO/N=C/1\[C@H]2O[C@H]2[C@@H](O)[C@H]3[C@@H]1CCn4n3c(=O)n(c5ccccc5)c4=O 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P20 compound treatment 701245.0 135000.0 0.99 633782.0 65400.0 0.5 1.0486 0.9496 3131985 CMLD2_000914 COC(=O)C1=C(C)N(Cc2ccccc2)C3=C4[C@H](C(=O)N(C)C4=O)[C@@](O)(C(=O)OC)C(=O)N3[C@@H]1c5ccccc5 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P21 compound treatment 716730.0 150000.0 1.1 665597.0 97200.0 0.74 1.2996 0.9813 3130651 CMLD2_000915 C[C@@H]1CC[C@@H]2N(C[C@H](COC=C)OC2=O)[C@H]1c3ccc(Br)cc3 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P22 mock treatment 739837.0 173000.0 1.27 625528.0 57100.0 0.43 1.2038 0.898 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P23 mock treatment 786977.0 221000.0 1.61 576172.0 7780.0 0.06 1.1824 0.7325 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.2111 P24 mock treatment 711275.0 145000.0 1.06 578337.0 9940.0 0.08 0.8026 0.7556 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A01 mock treatment 502131.0 -144000.0 -1.05 565691.0 -72500.0 -0.55 -1.1342 -0.9542 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A02 mock treatment 552824.0 -93400.0 -0.68 590432.0 -47700.0 -0.36 -0.7391 -0.9561 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A03 mock treatment 514447.0 -132000.0 -0.96 617075.0 -21100.0 -0.16 -0.7945 -0.8134 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A04 mock treatment 553220.0 -93000.0 -0.68 646764.0 8620.0 0.07 -0.4345 -0.6361 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A05 mock treatment 516104.0 -130000.0 -0.95 573958.0 -64200.0 -0.49 -1.0175 -0.9518 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A06 mock treatment 511494.0 -135000.0 -0.99 595668.0 -42500.0 -0.32 -0.9247 -0.8921 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A07 mock treatment 476445.0 -170000.0 -1.24 590367.0 -47800.0 -0.36 -1.1345 -0.8771 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A08 mock treatment 434199.0 -212000.0 -1.55 585426.0 -52700.0 -0.4 -1.3795 -0.8615 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A09 mock treatment 515774.0 -130000.0 -0.95 568251.0 -69900.0 -0.53 -1.0499 -0.9618 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A10 mock treatment 492341.0 -154000.0 -1.13 538691.0 -99500.0 -0.76 -1.3298 -0.9812 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A11 mock treatment 567790.0 -78400.0 -0.57 523438.0 -115000.0 -0.87 -1.0216 -0.9794 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A12 mock treatment 557132.0 -89100.0 -0.65 531285.0 -107000.0 -0.81 -1.0346 -0.994 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A13 mock treatment 539592.0 -107000.0 -0.78 584768.0 -53400.0 -0.41 -0.838 -0.9536 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A14 mock treatment 460843.0 -185000.0 -1.36 534098.0 -104000.0 -0.79 -1.5174 -0.967 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A15 mock treatment 563053.0 -83100.0 -0.61 562517.0 -75600.0 -0.57 -0.8362 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A16 mock treatment 505908.0 -140000.0 -1.03 605325.0 -32800.0 -0.25 -0.9018 -0.8541 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A17 mock treatment 564183.0 -82000.0 -0.6 631614.0 -6530.0 -0.05 -0.4592 -0.763 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A18 mock treatment 537934.0 -108000.0 -0.79 481513.0 -157000.0 -1.19 -1.4012 -0.9804 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A19 mock treatment 553424.0 -92800.0 -0.68 572004.0 -66100.0 -0.5 -0.835 -0.9891 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A20 mock treatment 464959.0 -181000.0 -1.33 585586.0 -52600.0 -0.4 -1.2195 -0.881 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A21 mock treatment 560176.0 -86000.0 -0.63 676644.0 38500.0 0.29 -0.238 -0.3431 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A22 mock treatment 641138.0 -5060.0 -0.04 600357.0 -37800.0 -0.29 -0.2291 -0.7917 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A23 mock treatment 557934.0 -88300.0 -0.65 580725.0 -57400.0 -0.44 -0.7649 -0.9818 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base A24 mock treatment 649311.0 3110.0 0.02 581396.0 -56700.0 -0.43 -0.2887 -0.6688 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B01 mock treatment 596392.0 -49800.0 -0.36 625714.0 -12400.0 -0.09 -0.3243 -0.8619 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B02 mock treatment 578404.0 -67800.0 -0.5 553236.0 -84900.0 -0.65 -0.8067 -0.9916 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B03 mock treatment 572044.0 -74200.0 -0.54 625584.0 -12600.0 -0.1 -0.4509 -0.8189 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B04 mock treatment 548223.0 -98000.0 -0.72 674210.0 36100.0 0.27 -0.3129 -0.4079 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B05 mock treatment 606571.0 -39600.0 -0.29 686847.0 48700.0 0.37 0.0567 0.1207 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B06 mock treatment 602835.0 -43400.0 -0.32 609568.0 -28600.0 -0.22 -0.3777 -0.9829 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B07 mock treatment 577449.0 -68700.0 -0.5 570315.0 -67800.0 -0.52 -0.7199 -0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B08 mock treatment 492232.0 -154000.0 -1.13 605465.0 -32700.0 -0.25 -0.9717 -0.8428 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B09 mock treatment 628737.0 -17500.0 -0.13 634093.0 -4050.0 -0.03 -0.112 -0.8531 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B10 mock treatment 605858.0 -40300.0 -0.3 610630.0 -27500.0 -0.21 -0.3564 -0.9858 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B11 mock treatment 582433.0 -63800.0 -0.47 611442.0 -26700.0 -0.2 -0.4732 -0.9305 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B12 mock treatment 549890.0 -96300.0 -0.7 578809.0 -59300.0 -0.45 -0.8168 -0.9767 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B13 mock treatment 508687.0 -138000.0 -1.01 650758.0 12600.0 0.1 -0.6433 -0.6368 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B14 mock treatment 582590.0 -63600.0 -0.47 566247.0 -71900.0 -0.55 -0.7151 -0.9968 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B15 mock treatment 614800.0 -31400.0 -0.23 560653.0 -77500.0 -0.59 -0.5786 -0.9157 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B16 mock treatment 511256.0 -135000.0 -0.99 655876.0 17700.0 0.13 -0.6025 -0.605 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B17 mock treatment 622082.0 -24100.0 -0.18 634719.0 -3420.0 -0.03 -0.1431 -0.8027 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B18 mock treatment 606584.0 -39600.0 -0.29 590438.0 -47700.0 -0.36 -0.4611 -0.9938 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B19 mock treatment 614491.0 -31700.0 -0.23 659249.0 21100.0 0.16 -0.0506 -0.1794 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B20 mock treatment 546343.0 -99900.0 -0.73 588034.0 -50100.0 -0.38 -0.7855 -0.9539 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B21 mock treatment 550031.0 -96200.0 -0.7 573559.0 -64600.0 -0.49 -0.8442 -0.9845 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B22 mock treatment 610793.0 -35400.0 -0.26 605099.0 -33000.0 -0.25 -0.3606 -0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B23 mock treatment 608301.0 -37900.0 -0.28 673894.0 35800.0 0.27 -0.0039 -0.0101 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base B24 mock treatment 693807.0 47600.0 0.35 579188.0 -59000.0 -0.45 -0.0705 -0.1243 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C01 mock treatment 531176.0 -115000.0 -0.84 538633.0 -99500.0 -0.76 -1.1293 -0.9986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C02 mock treatment 529374.0 -117000.0 -0.85 488077.0 -150000.0 -1.14 -1.4102 -0.9899 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C03 mock treatment 588045.0 -58200.0 -0.43 568597.0 -69500.0 -0.53 -0.6743 -0.9942 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C04 mock treatment 587928.0 -58300.0 -0.43 549653.0 -88500.0 -0.67 -0.7767 -0.9758 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C05 mock treatment 583932.0 -62300.0 -0.46 615115.0 -23000.0 -0.17 -0.4457 -0.9137 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C06 mock treatment 578895.0 -67300.0 -0.49 541376.0 -96800.0 -0.74 -0.8678 -0.981 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C07 mock treatment 534471.0 -112000.0 -0.82 559192.0 -79000.0 -0.6 -1.0019 -0.9884 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C08 mock treatment 612854.0 -33300.0 -0.24 566121.0 -72000.0 -0.55 -0.5593 -0.9337 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C09 mock treatment 477886.0 -168000.0 -1.23 568575.0 -69600.0 -0.53 -1.2441 -0.9287 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C10 mock treatment 630210.0 -16000.0 -0.12 599660.0 -38500.0 -0.29 -0.2894 -0.9191 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C11 mock treatment 561341.0 -84900.0 -0.62 620045.0 -18100.0 -0.14 -0.536 -0.8433 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C12 mock treatment 637696.0 -8500.0 -0.06 576990.0 -61200.0 -0.46 -0.3725 -0.7946 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C13 mock treatment 576884.0 -69300.0 -0.51 664238.0 26100.0 0.2 -0.2183 -0.401 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C14 mock treatment 591101.0 -55100.0 -0.4 614170.0 -24000.0 -0.18 -0.4137 -0.9356 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C15 mock treatment 615187.0 -31000.0 -0.23 633759.0 -4380.0 -0.03 -0.1839 -0.8024 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C16 mock treatment 626142.0 -20100.0 -0.15 637023.0 -1120.0 -0.01 -0.1097 -0.7469 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C17 mock treatment 568887.0 -77300.0 -0.57 528077.0 -110000.0 -0.84 -0.991 -0.9818 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C18 mock treatment 581812.0 -64400.0 -0.47 572491.0 -65700.0 -0.5 -0.6856 -0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C19 mock treatment 645502.0 -695.0 -0.01 603462.0 -34700.0 -0.26 -0.1899 -0.7206 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C20 mock treatment 623105.0 -23100.0 -0.17 630030.0 -8110.0 -0.06 -0.163 -0.9067 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C21 mock treatment 625712.0 -20500.0 -0.15 641917.0 3770.0 0.03 -0.0857 -0.5616 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C22 mock treatment 590483.0 -55700.0 -0.41 609335.0 -28800.0 -0.22 -0.4429 -0.9575 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C23 mock treatment 608518.0 -37700.0 -0.28 646500.0 8360.0 0.06 -0.15 -0.5303 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base C24 mock treatment 666467.0 20300.0 0.15 525167.0 -113000.0 -0.86 -0.5021 -0.5764 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D01 mock treatment 570734.0 -75500.0 -0.55 611771.0 -26400.0 -0.2 -0.5319 -0.906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D02 mock treatment 659808.0 13600.0 0.1 571778.0 -66400.0 -0.5 -0.2861 -0.5568 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D03 mock treatment 622331.0 -23900.0 -0.17 551196.0 -86900.0 -0.66 -0.5905 -0.8643 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D04 mock treatment 693413.0 47200.0 0.35 599633.0 -38500.0 -0.29 0.0373 0.0824 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D05 mock treatment 558998.0 -87200.0 -0.64 619225.0 -18900.0 -0.14 -0.5525 -0.8453 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D06 mock treatment 608358.0 -37800.0 -0.28 611194.0 -26900.0 -0.2 -0.3404 -0.989 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D07 mock treatment 618354.0 -27800.0 -0.2 693925.0 55800.0 0.42 0.1557 0.3311 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D08 mock treatment 567590.0 -78600.0 -0.57 598591.0 -39600.0 -0.3 -0.619 -0.9542 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D09 mock treatment 620673.0 -25500.0 -0.19 630618.0 -7530.0 -0.06 -0.1724 -0.8832 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D10 mock treatment 611904.0 -34300.0 -0.25 510410.0 -128000.0 -0.97 -0.8635 -0.8615 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D11 mock treatment 551603.0 -94600.0 -0.69 648049.0 9910.0 0.08 -0.436 -0.6265 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D12 mock treatment 637323.0 -8870.0 -0.06 550045.0 -88100.0 -0.67 -0.5191 -0.7721 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D13 mock treatment 708664.0 62500.0 0.46 660873.0 22700.0 0.17 0.4451 0.9114 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D14 mock treatment 618303.0 -27900.0 -0.2 583648.0 -54500.0 -0.41 -0.437 -0.9468 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D15 mock treatment 648823.0 2630.0 0.02 581588.0 -56600.0 -0.43 -0.2902 -0.6748 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D16 mock treatment 607550.0 -38600.0 -0.28 653299.0 15200.0 0.12 -0.1184 -0.3881 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D17 mock treatment 647030.0 833.0 0.01 628802.0 -9340.0 -0.07 -0.0459 -0.6441 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D18 mock treatment 622980.0 -23200.0 -0.17 673898.0 35800.0 0.27 0.072 0.2248 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D19 mock treatment 638875.0 -7320.0 -0.05 660041.0 21900.0 0.17 0.0798 0.4564 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D20 mock treatment 605950.0 -40200.0 -0.29 628034.0 -10100.0 -0.08 -0.2624 -0.8627 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D21 mock treatment 553368.0 -92800.0 -0.68 697111.0 59000.0 0.45 -0.1633 -0.2007 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D22 mock treatment 682070.0 35900.0 0.26 645433.0 7290.0 0.06 0.2247 0.8379 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D23 mock treatment 703791.0 57600.0 0.42 646625.0 8480.0 0.06 0.3434 0.8059 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base D24 mock treatment 595484.0 -50700.0 -0.37 633887.0 -4260.0 -0.03 -0.2851 -0.7659 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E01 mock treatment 608138.0 -38100.0 -0.28 551608.0 -86500.0 -0.66 -0.6617 -0.9268 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E02 mock treatment 564363.0 -81800.0 -0.6 550281.0 -87900.0 -0.67 -0.8952 -0.9985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E03 mock treatment 630182.0 -16000.0 -0.12 591526.0 -46600.0 -0.35 -0.3332 -0.8934 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E04 mock treatment 577758.0 -68400.0 -0.5 581134.0 -57000.0 -0.43 -0.6602 -0.9974 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E05 mock treatment 530025.0 -116000.0 -0.85 608070.0 -30100.0 -0.23 -0.7623 -0.8665 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E06 mock treatment 543518.0 -103000.0 -0.75 598829.0 -39300.0 -0.3 -0.7422 -0.9184 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E07 mock treatment 613482.0 -32700.0 -0.24 588112.0 -50000.0 -0.38 -0.4379 -0.9751 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E08 mock treatment 648228.0 2030.0 0.01 607182.0 -31000.0 -0.24 -0.1558 -0.6611 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E09 mock treatment 590854.0 -55300.0 -0.4 643149.0 5010.0 0.04 -0.2593 -0.6379 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E10 mock treatment 514927.0 -131000.0 -0.96 579352.0 -58800.0 -0.45 -0.9946 -0.9394 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E11 mock treatment 668865.0 22700.0 0.17 526941.0 -111000.0 -0.84 -0.4801 -0.5577 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E12 mock treatment 608576.0 -37600.0 -0.28 613813.0 -24300.0 -0.18 -0.3252 -0.9813 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E13 mock treatment 547393.0 -98800.0 -0.72 530530.0 -108000.0 -0.82 -1.089 -0.9981 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E14 mock treatment 599820.0 -46400.0 -0.34 521146.0 -117000.0 -0.89 -0.8683 -0.9127 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E15 mock treatment 629875.0 -16300.0 -0.12 628061.0 -10100.0 -0.08 -0.1386 -0.977 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E16 mock treatment 724082.0 77900.0 0.57 699583.0 61400.0 0.47 0.7328 0.9951 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E17 mock treatment 613698.0 -32500.0 -0.24 619882.0 -18300.0 -0.14 -0.2662 -0.9671 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E18 mock treatment 645234.0 -963.0 -0.01 684585.0 46400.0 0.35 0.2445 0.6929 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E19 mock treatment 690509.0 44300.0 0.32 627032.0 -11100.0 -0.08 0.1695 0.506 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E20 mock treatment 735268.0 89100.0 0.65 668506.0 30400.0 0.23 0.6237 0.9026 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E21 mock treatment 735270.0 89100.0 0.65 768680.0 131000.0 0.99 1.1618 0.9792 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E22 mock treatment 631228.0 -15000.0 -0.11 724491.0 86300.0 0.66 0.3864 0.5811 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E23 mock treatment 625444.0 -20800.0 -0.15 638395.0 251.0 0.0 -0.106 -0.6982 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base E24 mock treatment 572134.0 -74100.0 -0.54 640217.0 2070.0 0.02 -0.3719 -0.6863 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F01 mock treatment 541903.0 -104000.0 -0.76 519550.0 -119000.0 -0.9 -1.1764 -0.9966 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F02 mock treatment 623682.0 -22500.0 -0.16 592579.0 -45600.0 -0.35 -0.3612 -0.9423 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F03 mock treatment 644704.0 -1490.0 -0.01 582587.0 -55600.0 -0.42 -0.3062 -0.7252 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F04 mock treatment 480557.0 -166000.0 -1.21 585881.0 -52300.0 -0.4 -1.1373 -0.8922 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F05 mock treatment 555014.0 -91200.0 -0.67 610003.0 -28100.0 -0.21 -0.6227 -0.8892 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F06 mock treatment 577044.0 -69200.0 -0.51 509006.0 -129000.0 -0.98 -1.0513 -0.9525 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F07 mock treatment 647833.0 1640.0 0.01 556138.0 -82000.0 -0.62 -0.4321 -0.6934 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F08 mock treatment 598080.0 -48100.0 -0.35 654854.0 16700.0 0.13 -0.1591 -0.4252 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F09 mock treatment 581338.0 -64900.0 -0.47 625886.0 -12300.0 -0.09 -0.4012 -0.8301 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F10 mock treatment 609456.0 -36700.0 -0.27 672109.0 34000.0 0.26 -0.0075 -0.0202 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F11 mock treatment 670060.0 23900.0 0.17 538884.0 -99300.0 -0.75 -0.4098 -0.5295 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F12 mock treatment 596523.0 -49700.0 -0.36 588561.0 -49600.0 -0.38 -0.5232 -0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F13 mock treatment 609285.0 -36900.0 -0.27 629520.0 -8620.0 -0.07 -0.2372 -0.8539 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F14 mock treatment 715906.0 69700.0 0.51 612332.0 -25800.0 -0.2 0.2218 0.4061 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F15 mock treatment 625143.0 -21100.0 -0.15 646735.0 8590.0 0.07 -0.0627 -0.3751 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F16 mock treatment 688058.0 41900.0 0.31 625277.0 -12900.0 -0.1 0.1474 0.4585 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F17 mock treatment 614663.0 -31500.0 -0.23 715099.0 77000.0 0.58 0.2503 0.3983 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F18 mock treatment 656288.0 10100.0 0.07 668004.0 29900.0 0.23 0.2126 0.8912 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F19 mock treatment 755462.0 109000.0 0.8 663667.0 25500.0 0.19 0.7021 0.8539 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F20 mock treatment 724319.0 78100.0 0.57 699158.0 61000.0 0.46 0.7317 0.9946 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F21 mock treatment 672430.0 26200.0 0.19 730326.0 92200.0 0.7 0.6308 0.8688 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F22 mock treatment 630018.0 -16200.0 -0.12 714921.0 76800.0 0.58 0.3288 0.5524 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F23 mock treatment 651654.0 5460.0 0.04 662390.0 24200.0 0.18 0.1585 0.8408 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base F24 mock treatment 645676.0 -521.0 0.0 635124.0 -3020.0 -0.02 -0.0189 -0.8134 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G01 mock treatment 500629.0 -146000.0 -1.06 649559.0 11400.0 0.09 -0.6914 -0.6474 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G02 mock treatment 622979.0 -23200.0 -0.17 601776.0 -36400.0 -0.28 -0.3154 -0.9727 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G03 mock treatment 561914.0 -84300.0 -0.62 555754.0 -82400.0 -0.63 -0.8784 -1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G04 mock treatment 651548.0 5350.0 0.04 580066.0 -58100.0 -0.44 -0.2843 -0.6419 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G05 mock treatment 646868.0 671.0 0.0 550102.0 -88000.0 -0.67 -0.4695 -0.7019 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G06 mock treatment 643640.0 -2560.0 -0.02 560365.0 -77800.0 -0.59 -0.431 -0.7291 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G07 mock treatment 631791.0 -14400.0 -0.11 605283.0 -32900.0 -0.25 -0.251 -0.9264 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G08 mock treatment 627436.0 -18800.0 -0.14 520684.0 -117000.0 -0.89 -0.728 -0.8064 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G09 mock treatment 623948.0 -22200.0 -0.16 636326.0 -1820.0 -0.01 -0.1248 -0.7644 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G10 mock treatment 589427.0 -56800.0 -0.42 672482.0 34300.0 0.26 -0.1091 -0.2225 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G11 mock treatment 582421.0 -63800.0 -0.47 610328.0 -27800.0 -0.21 -0.4792 -0.9359 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G12 mock treatment 603772.0 -42400.0 -0.31 478185.0 -160000.0 -1.22 -1.0786 -0.8601 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G13 mock treatment 599837.0 -46400.0 -0.34 644599.0 6460.0 0.05 -0.2051 -0.5986 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G14 mock treatment 635712.0 -10500.0 -0.08 624727.0 -13400.0 -0.1 -0.1263 -0.9902 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G15 mock treatment 616212.0 -30000.0 -0.22 686298.0 48200.0 0.37 0.1036 0.2429 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G16 mock treatment 785907.0 140000.0 1.02 623385.0 -14800.0 -0.11 0.6432 0.6258 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G17 mock treatment 732970.0 86800.0 0.63 677558.0 39400.0 0.3 0.6604 0.9412 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G18 mock treatment 720618.0 74400.0 0.54 744897.0 107000.0 0.81 0.9583 0.9812 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G19 mock treatment 679906.0 33700.0 0.25 646932.0 8790.0 0.07 0.2215 0.8674 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G20 mock treatment 712552.0 66400.0 0.49 615031.0 -23100.0 -0.18 0.219 0.4243 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G21 mock treatment 619224.0 -27000.0 -0.2 615612.0 -22500.0 -0.17 -0.2605 -0.9975 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G22 mock treatment 699163.0 53000.0 0.39 664483.0 26300.0 0.2 0.4154 0.9528 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G23 mock treatment 680949.0 34800.0 0.25 655704.0 17600.0 0.13 0.274 0.9547 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base G24 mock treatment 650813.0 4620.0 0.03 628563.0 -9580.0 -0.07 -0.0276 -0.344 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H01 mock treatment 620463.0 -25700.0 -0.19 615197.0 -22900.0 -0.17 -0.2563 -0.9993 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H02 mock treatment 541899.0 -104000.0 -0.76 557515.0 -80600.0 -0.61 -0.9725 -0.9941 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H03 mock treatment 685999.0 39800.0 0.29 577093.0 -61100.0 -0.46 -0.1221 -0.223 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H04 mock treatment 602694.0 -43500.0 -0.32 505638.0 -133000.0 -1.01 -0.9367 -0.8873 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H05 mock treatment 598581.0 -47600.0 -0.35 578917.0 -59200.0 -0.45 -0.5644 -0.992 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H06 mock treatment 583376.0 -62800.0 -0.46 602564.0 -35600.0 -0.27 -0.516 -0.968 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H07 mock treatment 587836.0 -58400.0 -0.43 616770.0 -21400.0 -0.16 -0.4166 -0.9123 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H08 mock treatment 596228.0 -50000.0 -0.37 615329.0 -22800.0 -0.17 -0.381 -0.9419 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H09 mock treatment 686254.0 40100.0 0.29 640438.0 2290.0 0.02 0.2195 0.7479 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H10 mock treatment 623552.0 -22600.0 -0.17 696289.0 58100.0 0.44 0.1952 0.4139 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H11 mock treatment 661769.0 15600.0 0.11 503721.0 -134000.0 -1.02 -0.6416 -0.6244 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H12 mock treatment 719330.0 73100.0 0.53 606763.0 -31400.0 -0.24 0.2096 0.358 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H13 mock treatment 617381.0 -28800.0 -0.21 509669.0 -128000.0 -0.98 -0.8391 -0.8404 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H14 mock treatment 612006.0 -34200.0 -0.25 623954.0 -14200.0 -0.11 -0.253 -0.9293 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H15 mock treatment 707545.0 61300.0 0.45 705284.0 67100.0 0.51 0.6779 0.998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H16 mock treatment 697033.0 50800.0 0.37 652528.0 14400.0 0.11 0.3401 0.8778 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H17 mock treatment 659860.0 13700.0 0.1 688473.0 50300.0 0.38 0.341 0.8629 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H18 mock treatment 593264.0 -52900.0 -0.39 595523.0 -42600.0 -0.32 -0.5027 -0.9961 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H19 mock treatment 746486.0 100000.0 0.73 806866.0 169000.0 1.28 1.4249 0.9649 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H20 mock treatment 733551.0 87400.0 0.64 682371.0 44200.0 0.34 0.6893 0.955 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H21 mock treatment 727978.0 81800.0 0.6 707585.0 69400.0 0.53 0.7959 0.998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H22 mock treatment 654085.0 7890.0 0.06 720678.0 82500.0 0.63 0.4841 0.7689 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H23 mock treatment 709873.0 63700.0 0.47 735511.0 97400.0 0.74 0.8523 0.9751 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base H24 mock treatment 682523.0 36300.0 0.27 636786.0 -1360.0 -0.01 0.1806 0.6791 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I01 mock treatment 561185.0 -85000.0 -0.62 530909.0 -107000.0 -0.81 -1.0156 -0.9911 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I02 mock treatment 590156.0 -56000.0 -0.41 507524.0 -131000.0 -0.99 -0.9915 -0.9235 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I03 mock treatment 745352.0 99200.0 0.73 661323.0 23200.0 0.18 0.6373 0.854 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I04 mock treatment 645480.0 -717.0 -0.01 654994.0 16900.0 0.13 0.0868 0.6776 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I05 mock treatment 651382.0 5180.0 0.04 648880.0 10700.0 0.08 0.0845 0.9393 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I06 mock treatment 602580.0 -43600.0 -0.32 613656.0 -24500.0 -0.19 -0.3571 -0.9671 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I07 mock treatment 648255.0 2060.0 0.02 637976.0 -168.0 0.0 0.0097 0.6448 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I08 mock treatment 656266.0 10100.0 0.07 585700.0 -52400.0 -0.4 -0.2296 -0.5668 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I09 mock treatment 668868.0 22700.0 0.17 599014.0 -39100.0 -0.3 -0.093 -0.2731 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I10 mock treatment 586661.0 -59500.0 -0.44 554399.0 -83700.0 -0.64 -0.7577 -0.9829 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I11 mock treatment 593858.0 -52300.0 -0.38 538829.0 -99300.0 -0.75 -0.8041 -0.9505 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I12 mock treatment 704149.0 58000.0 0.42 481083.0 -157000.0 -1.19 -0.544 -0.4296 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I13 mock treatment 688337.0 42100.0 0.31 665998.0 27900.0 0.21 0.3675 0.9832 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I14 mock treatment 719066.0 72900.0 0.53 557001.0 -81100.0 -0.62 -0.0591 -0.0725 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I15 mock treatment 729257.0 83100.0 0.61 725632.0 87500.0 0.66 0.8995 0.999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I16 mock treatment 717524.0 71300.0 0.52 574875.0 -63300.0 -0.48 0.029 0.0409 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I17 mock treatment 764044.0 118000.0 0.86 755641.0 117000.0 0.89 1.2406 0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I18 mock treatment 765061.0 119000.0 0.87 635823.0 -2320.0 -0.02 0.6022 0.6926 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I19 mock treatment 766195.0 120000.0 0.88 607354.0 -30800.0 -0.23 0.4551 0.5011 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I20 mock treatment 750186.0 104000.0 0.76 573883.0 -64300.0 -0.49 0.1925 0.2131 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I21 mock treatment 769049.0 123000.0 0.9 717677.0 79500.0 0.6 1.0625 0.9814 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I22 mock treatment 575475.0 -70700.0 -0.52 684718.0 46600.0 0.35 -0.1155 -0.1844 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I23 mock treatment 642818.0 -3380.0 -0.02 648432.0 10300.0 0.08 0.0378 0.461 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base I24 mock treatment 688383.0 42200.0 0.31 642819.0 4680.0 0.04 0.2433 0.7833 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J01 mock treatment 550867.0 -95300.0 -0.7 617150.0 -21000.0 -0.16 -0.6057 -0.847 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J02 mock treatment 591316.0 -54900.0 -0.4 582624.0 -55500.0 -0.42 -0.582 -0.9997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J03 mock treatment 636575.0 -9620.0 -0.07 622585.0 -15600.0 -0.12 -0.1333 -0.9693 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J04 mock treatment 562086.0 -84100.0 -0.62 547536.0 -90600.0 -0.69 -0.9217 -0.9984 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J05 mock treatment 564844.0 -81400.0 -0.59 547266.0 -90900.0 -0.69 -0.9089 -0.9973 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J06 mock treatment 630722.0 -15500.0 -0.11 655436.0 17300.0 0.13 0.0129 0.0742 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J07 mock treatment 747368.0 101000.0 0.74 593760.0 -44400.0 -0.34 0.2848 0.3502 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J08 mock treatment 579954.0 -66200.0 -0.48 596851.0 -41300.0 -0.31 -0.5644 -0.9779 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J09 mock treatment 653787.0 7590.0 0.06 723733.0 85600.0 0.65 0.499 0.7647 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J10 mock treatment 663274.0 17100.0 0.12 608708.0 -29400.0 -0.22 -0.0698 -0.2726 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J11 mock treatment 625940.0 -20300.0 -0.15 705331.0 67200.0 0.51 0.2562 0.482 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J12 mock treatment 655825.0 9630.0 0.07 520508.0 -118000.0 -0.89 -0.5821 -0.6494 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J13 mock treatment 578004.0 -68200.0 -0.5 584805.0 -53300.0 -0.41 -0.6392 -0.9947 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J14 mock treatment 749043.0 103000.0 0.75 678596.0 40500.0 0.31 0.7491 0.922 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J15 mock treatment 718468.0 72300.0 0.53 753129.0 115000.0 0.87 0.9914 0.971 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J16 mock treatment 790547.0 144000.0 1.06 810196.0 172000.0 1.31 1.6707 0.9944 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J17 mock treatment 750279.0 104000.0 0.76 711085.0 72900.0 0.55 0.93 0.9878 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J18 mock treatment 753669.0 107000.0 0.79 672706.0 34600.0 0.26 0.7414 0.8947 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J19 mock treatment 795383.0 149000.0 1.09 686562.0 48400.0 0.37 1.0316 0.896 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J20 mock treatment 812088.0 166000.0 1.21 637510.0 -634.0 0.0 0.8544 0.7043 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J21 mock treatment 664362.0 18200.0 0.13 627195.0 -10900.0 -0.08 0.0351 0.2241 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J22 mock treatment 780712.0 135000.0 0.98 735151.0 97000.0 0.74 1.2167 0.9899 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J23 mock treatment 649318.0 3120.0 0.02 732158.0 94000.0 0.71 0.5212 0.7293 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base J24 mock treatment 625555.0 -20600.0 -0.15 673199.0 35100.0 0.27 0.0816 0.2664 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K01 mock treatment 603546.0 -42700.0 -0.31 587822.0 -50300.0 -0.38 -0.4909 -0.9949 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K02 mock treatment 589358.0 -56800.0 -0.42 642546.0 4400.0 0.03 -0.2703 -0.6481 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K03 mock treatment 665452.0 19300.0 0.14 682990.0 44800.0 0.34 0.3405 0.9236 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K04 mock treatment 683363.0 37200.0 0.27 594398.0 -43700.0 -0.33 -0.0428 -0.0997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K05 mock treatment 636135.0 -10100.0 -0.07 588377.0 -49800.0 -0.38 -0.3194 -0.8292 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K06 mock treatment 699522.0 53300.0 0.39 552352.0 -85800.0 -0.65 -0.1851 -0.2437 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K07 mock treatment 674035.0 27800.0 0.2 562849.0 -75300.0 -0.57 -0.2605 -0.4291 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K08 mock treatment 657839.0 11600.0 0.09 608829.0 -29300.0 -0.22 -0.0973 -0.408 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K09 mock treatment 608785.0 -37400.0 -0.27 594782.0 -43400.0 -0.33 -0.4264 -0.9957 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K10 mock treatment 656662.0 10500.0 0.08 567470.0 -70700.0 -0.54 -0.3255 -0.6002 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K11 mock treatment 652412.0 6210.0 0.05 596983.0 -41200.0 -0.31 -0.189 -0.598 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K12 mock treatment 722098.0 75900.0 0.56 672801.0 34700.0 0.26 0.5787 0.9419 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K13 mock treatment 692031.0 45800.0 0.34 642515.0 4370.0 0.03 0.2605 0.7734 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K14 mock treatment 655532.0 9330.0 0.07 634559.0 -3580.0 -0.03 0.029 0.3948 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K15 mock treatment 711452.0 65300.0 0.48 670553.0 32400.0 0.25 0.5115 0.9526 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K16 mock treatment 696534.0 50300.0 0.37 599603.0 -38500.0 -0.29 0.0533 0.1132 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K17 mock treatment 723513.0 77300.0 0.57 644046.0 5900.0 0.04 0.4315 0.7608 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K18 mock treatment 703095.0 56900.0 0.42 591307.0 -46800.0 -0.36 0.0426 0.0779 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K19 mock treatment 674722.0 28500.0 0.21 576772.0 -61400.0 -0.47 -0.1822 -0.3567 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K20 mock treatment 644400.0 -1800.0 -0.01 710599.0 72500.0 0.55 0.3799 0.69 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K21 mock treatment 732402.0 86200.0 0.63 608804.0 -29300.0 -0.22 0.2882 0.431 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K22 mock treatment 710474.0 64300.0 0.47 689356.0 51200.0 0.39 0.6075 0.9956 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K23 mock treatment 676920.0 30700.0 0.22 627198.0 -10900.0 -0.08 0.1001 0.4177 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base K24 mock treatment 641511.0 -4690.0 -0.03 659386.0 21200.0 0.16 0.0899 0.5448 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L01 mock treatment 642231.0 -3970.0 -0.03 639938.0 1790.0 0.01 -0.0109 -0.3393 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L02 mock treatment 616957.0 -29200.0 -0.21 558932.0 -79200.0 -0.6 -0.5767 -0.9031 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L03 mock treatment 619529.0 -26700.0 -0.2 627609.0 -10500.0 -0.08 -0.1945 -0.9226 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L04 mock treatment 692842.0 46600.0 0.34 544032.0 -94100.0 -0.71 -0.2643 -0.3337 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L05 mock treatment 663311.0 17100.0 0.13 523519.0 -115000.0 -0.87 -0.5272 -0.5993 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L06 mock treatment 634707.0 -11500.0 -0.08 549272.0 -88900.0 -0.68 -0.5368 -0.789 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L07 mock treatment 763317.0 117000.0 0.86 578912.0 -59200.0 -0.45 0.2875 0.2971 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L08 mock treatment 704284.0 58100.0 0.42 611072.0 -27100.0 -0.21 0.155 0.3283 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L09 mock treatment 637052.0 -9150.0 -0.07 643493.0 5350.0 0.04 -0.0186 -0.2371 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L10 mock treatment 679623.0 33400.0 0.24 558454.0 -79700.0 -0.61 -0.2552 -0.3909 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L11 mock treatment 548621.0 -97600.0 -0.71 662756.0 24600.0 0.19 -0.3724 -0.5048 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L12 mock treatment 663190.0 17000.0 0.12 572827.0 -65300.0 -0.5 -0.263 -0.5141 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L13 mock treatment 681156.0 35000.0 0.26 617759.0 -20400.0 -0.15 0.0713 0.2385 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L14 mock treatment 727274.0 81100.0 0.59 712987.0 74800.0 0.57 0.8213 0.9998 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L15 mock treatment 733916.0 87700.0 0.64 712156.0 74000.0 0.56 0.8512 0.9978 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L16 mock treatment 734217.0 88000.0 0.64 666838.0 28700.0 0.22 0.6093 0.8965 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L17 mock treatment 683671.0 37500.0 0.27 645153.0 7010.0 0.05 0.2314 0.829 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L18 mock treatment 721246.0 75000.0 0.55 607924.0 -30200.0 -0.23 0.2258 0.3795 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L19 mock treatment 626594.0 -19600.0 -0.14 568212.0 -69900.0 -0.53 -0.477 -0.8669 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L20 mock treatment 640821.0 -5380.0 -0.04 711713.0 73600.0 0.56 0.3674 0.6557 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L21 mock treatment 705466.0 59300.0 0.43 795329.0 157000.0 1.19 1.1508 0.9059 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L22 mock treatment 734724.0 88500.0 0.65 649694.0 11600.0 0.09 0.5198 0.7957 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L23 mock treatment 675702.0 29500.0 0.22 725820.0 87700.0 0.67 0.6235 0.8906 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base L24 mock treatment 657805.0 11600.0 0.08 600710.0 -37400.0 -0.28 -0.1411 -0.4753 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M01 mock treatment 585173.0 -61000.0 -0.45 607768.0 -30400.0 -0.23 -0.4787 -0.9529 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M02 mock treatment 498229.0 -148000.0 -1.08 577195.0 -60900.0 -0.46 -1.0926 -0.9283 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M03 mock treatment 724948.0 78800.0 0.58 675823.0 37700.0 0.29 0.6096 0.9479 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M04 mock treatment 729256.0 83100.0 0.61 643134.0 4990.0 0.04 0.4563 0.7498 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M05 mock treatment 589145.0 -57100.0 -0.42 610544.0 -27600.0 -0.21 -0.4433 -0.9493 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M06 mock treatment 717508.0 71300.0 0.52 637122.0 -1020.0 -0.01 0.3633 0.6965 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M07 mock treatment 706998.0 60800.0 0.44 562123.0 -76000.0 -0.58 -0.094 -0.1289 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M08 mock treatment 622736.0 -23500.0 -0.17 662447.0 24300.0 0.18 0.0092 0.0366 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M09 mock treatment 655579.0 9380.0 0.07 692640.0 54500.0 0.41 0.3413 0.8132 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M10 mock treatment 729813.0 83600.0 0.61 697809.0 59700.0 0.45 0.7529 0.9891 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M11 mock treatment 650527.0 4330.0 0.03 636224.0 -1920.0 -0.01 0.0121 0.3464 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M12 mock treatment 604645.0 -41600.0 -0.3 623657.0 -14500.0 -0.11 -0.2927 -0.9056 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M13 mock treatment 697178.0 51000.0 0.37 685998.0 47900.0 0.36 0.5207 0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M14 mock treatment 714321.0 68100.0 0.5 653117.0 15000.0 0.11 0.4327 0.8468 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M15 mock treatment 743122.0 96900.0 0.71 678955.0 40800.0 0.31 0.7204 0.9312 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M16 mock treatment 741692.0 95500.0 0.7 725590.0 87400.0 0.66 0.9636 0.9997 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M17 mock treatment 635725.0 -10500.0 -0.08 716085.0 77900.0 0.59 0.3645 0.6106 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M18 mock treatment 580801.0 -65400.0 -0.48 674302.0 36200.0 0.27 -0.1439 -0.261 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M19 mock treatment 656911.0 10700.0 0.08 708581.0 70400.0 0.54 0.4338 0.8021 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M20 mock treatment 729134.0 82900.0 0.61 791339.0 153000.0 1.16 1.2518 0.9539 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M21 mock treatment 774080.0 128000.0 0.94 734808.0 96700.0 0.73 1.1806 0.9928 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M22 mock treatment 695606.0 49400.0 0.36 630163.0 -7980.0 -0.06 0.2126 0.5803 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M23 mock treatment 720352.0 74200.0 0.54 658804.0 20700.0 0.16 0.4944 0.8758 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base M24 mock treatment 653707.0 7510.0 0.05 650393.0 12200.0 0.09 0.1046 0.9684 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N01 mock treatment 566697.0 -79500.0 -0.58 638022.0 -122.0 0.0 -0.4118 -0.7082 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N02 mock treatment 679543.0 33300.0 0.24 623978.0 -14200.0 -0.11 0.0963 0.3614 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N03 mock treatment 695530.0 49300.0 0.36 574103.0 -64000.0 -0.49 -0.0889 -0.1468 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N04 mock treatment 641450.0 -4750.0 -0.03 700315.0 62200.0 0.47 0.3094 0.6534 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N05 mock treatment 694140.0 47900.0 0.35 700890.0 62700.0 0.48 0.585 0.9886 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N06 mock treatment 699064.0 52900.0 0.39 683730.0 45600.0 0.35 0.5183 0.9985 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N07 mock treatment 763924.0 118000.0 0.86 576532.0 -61600.0 -0.47 0.2778 0.2835 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N08 mock treatment 591055.0 -55100.0 -0.4 631167.0 -6980.0 -0.05 -0.3226 -0.7932 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N09 mock treatment 590972.0 -55200.0 -0.4 699519.0 61400.0 0.47 0.0441 0.0715 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N10 mock treatment 646274.0 76.9 0.0 762277.0 124000.0 0.94 0.6672 0.7075 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N11 mock treatment 607063.0 -39100.0 -0.29 543018.0 -95100.0 -0.72 -0.7134 -0.9178 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N12 mock treatment 579833.0 -66400.0 -0.49 582015.0 -56100.0 -0.43 -0.6447 -0.9979 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N13 mock treatment 718067.0 71900.0 0.53 709737.0 71600.0 0.54 0.7562 0.9999 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N14 mock treatment 561797.0 -84400.0 -0.62 625263.0 -12900.0 -0.1 -0.5056 -0.8091 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N15 mock treatment 716889.0 70700.0 0.52 644240.0 6100.0 0.05 0.3983 0.7674 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N16 mock treatment 599058.0 -47100.0 -0.34 723241.0 85100.0 0.65 0.2134 0.2912 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N17 mock treatment 614552.0 -31600.0 -0.23 785939.0 148000.0 1.12 0.6303 0.5498 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N18 mock treatment 738601.0 92400.0 0.68 812106.0 174000.0 1.32 1.4123 0.9515 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N19 mock treatment 800295.0 154000.0 1.13 738595.0 100000.0 0.76 1.3365 0.982 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N20 mock treatment 842503.0 196000.0 1.44 776771.0 139000.0 1.05 1.7598 0.9884 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N21 mock treatment 654576.0 8380.0 0.06 729957.0 91800.0 0.7 0.5365 0.7663 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N22 mock treatment 749677.0 103000.0 0.76 677349.0 39200.0 0.3 0.7457 0.9169 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N23 mock treatment 603932.0 -42300.0 -0.31 730412.0 92300.0 0.7 0.2771 0.3617 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base N24 mock treatment 768987.0 123000.0 0.9 755526.0 117000.0 0.89 1.2655 1.0 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O01 mock treatment 649367.0 3170.0 0.02 654330.0 16200.0 0.12 0.1033 0.8259 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O02 mock treatment 632362.0 -13800.0 -0.1 693075.0 54900.0 0.42 0.2235 0.5206 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O03 mock treatment 760550.0 114000.0 0.84 782726.0 145000.0 1.1 1.368 0.9909 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O04 mock treatment 731149.0 85000.0 0.62 771245.0 133000.0 1.01 1.1543 0.9726 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O05 mock treatment 730891.0 84700.0 0.62 817674.0 180000.0 1.36 1.4024 0.9362 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O06 mock treatment 575192.0 -71000.0 -0.52 763939.0 126000.0 0.96 0.3086 0.2837 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O07 mock treatment 680489.0 34300.0 0.25 704290.0 66100.0 0.5 0.5326 0.9484 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O08 mock treatment 664878.0 18700.0 0.14 721694.0 83600.0 0.63 0.5454 0.8401 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O09 mock treatment 751707.0 106000.0 0.77 825873.0 188000.0 1.43 1.554 0.9584 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O10 mock treatment 750796.0 105000.0 0.76 766291.0 128000.0 0.97 1.2293 0.9929 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O11 mock treatment 723593.0 77400.0 0.57 679816.0 41700.0 0.32 0.6241 0.9623 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O12 mock treatment 679022.0 32800.0 0.24 743092.0 105000.0 0.8 0.7335 0.8809 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O13 mock treatment 738237.0 92000.0 0.67 817472.0 179000.0 1.36 1.4393 0.9472 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O14 mock treatment 664478.0 18300.0 0.13 716450.0 78300.0 0.59 0.5152 0.8449 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O15 mock treatment 812761.0 167000.0 1.22 761974.0 124000.0 0.94 1.5265 0.9918 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O16 mock treatment 683479.0 37300.0 0.27 777907.0 140000.0 1.06 0.9436 0.8608 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O17 mock treatment 689532.0 43300.0 0.32 741495.0 103000.0 0.79 0.7793 0.9204 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O18 mock treatment 805027.0 159000.0 1.16 727907.0 89800.0 0.68 1.3035 0.9678 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O19 mock treatment 653083.0 6890.0 0.05 730276.0 92100.0 0.7 0.5305 0.756 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O20 mock treatment 713398.0 67200.0 0.49 799737.0 162000.0 1.23 1.2155 0.9193 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O21 mock treatment 817679.0 171000.0 1.25 708241.0 70100.0 0.53 1.2633 0.9272 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O22 mock treatment 704089.0 57900.0 0.42 675406.0 37300.0 0.28 0.4995 0.9808 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O23 mock treatment 693006.0 46800.0 0.34 676231.0 38100.0 0.29 0.4466 0.9965 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base O24 mock treatment 692308.0 46100.0 0.34 571335.0 -66800.0 -0.51 -0.1204 -0.1976 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P01 mock treatment 623207.0 -23000.0 -0.17 696229.0 58100.0 0.44 0.1931 0.409 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P02 mock treatment 640524.0 -5670.0 -0.04 753124.0 115000.0 0.87 0.5883 0.6728 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P03 mock treatment 719681.0 73500.0 0.54 797061.0 159000.0 1.21 1.2337 0.9336 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P04 mock treatment 750900.0 105000.0 0.77 772977.0 135000.0 1.02 1.2657 0.9897 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P05 mock treatment 715604.0 69400.0 0.51 731533.0 93400.0 0.71 0.8606 0.9865 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P06 mock treatment 671060.0 24900.0 0.18 695458.0 57300.0 0.44 0.4364 0.925 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P07 mock treatment 622626.0 -23600.0 -0.17 696349.0 58200.0 0.44 0.1908 0.402 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P08 mock treatment 676846.0 30600.0 0.22 771108.0 133000.0 1.01 0.8727 0.8435 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P09 mock treatment 687647.0 41400.0 0.3 737401.0 99300.0 0.75 0.7475 0.9198 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P10 mock treatment 640300.0 -5900.0 -0.04 885554.0 247000.0 1.88 1.2985 0.6907 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P11 mock treatment 789052.0 143000.0 1.04 754681.0 117000.0 0.89 1.3647 0.9966 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P12 mock treatment 784294.0 138000.0 1.01 763779.0 126000.0 0.95 1.389 0.9996 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P13 mock treatment 753133.0 107000.0 0.78 804005.0 166000.0 1.26 1.4439 0.9737 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P14 mock treatment 777016.0 131000.0 0.96 792378.0 154000.0 1.17 1.505 0.9949 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P15 mock treatment 738679.0 92500.0 0.68 810285.0 172000.0 1.31 1.4029 0.9529 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P16 mock treatment 757804.0 112000.0 0.82 840529.0 202000.0 1.54 1.6643 0.9561 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P17 mock treatment 696558.0 50400.0 0.37 814576.0 176000.0 1.34 1.2082 0.8692 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P18 mock treatment 729639.0 83400.0 0.61 805398.0 167000.0 1.27 1.3299 0.9435 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P19 mock treatment 782632.0 136000.0 1.0 729108.0 91000.0 0.69 1.1942 0.9839 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P20 mock treatment 790783.0 145000.0 1.06 701961.0 63800.0 0.48 1.0905 0.9375 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P21 mock treatment 688408.0 42200.0 0.31 847722.0 210000.0 1.59 1.3441 0.8288 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P22 mock treatment 774445.0 128000.0 0.94 742065.0 104000.0 0.79 1.2214 0.9963 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P23 mock treatment 681793.0 35600.0 0.26 702888.0 64700.0 0.49 0.5319 0.9557 1033.0003 Calcein-AM(1033.0003) PKCoreAssaySet 1033.0003.Base P24 mock treatment 728470.0 82300.0 0.6 704402.0 66300.0 0.5 0.7814 0.9961