ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A01 compound treatment 2680.0 2120.0 9.79 1920.0 1350.0 5.56 10.8573 0.9641 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A02 compound treatment 1920.0 1360.0 6.28 2080.0 1510.0 6.22 8.842 1.0 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A03 compound treatment 2200.0 1640.0 7.58 2040.0 1470.0 6.06 9.6397 0.9939 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A04 compound treatment 840.0 281.0 1.3 640.0 70.7 0.29 1.122 0.8449 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A05 compound treatment 720.0 161.0 0.74 1680.0 1110.0 4.57 3.7592 0.8112 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A06 compound treatment 600.0 40.6 0.19 400.0 -169.0 -0.7 -0.3605 -0.4991 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A07 compound treatment 2280.0 1720.0 7.94 2240.0 1670.0 6.88 10.4834 0.9974 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A08 compound treatment 840.0 281.0 1.3 1480.0 911.0 3.75 3.5685 0.8992 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A09 compound treatment 1680.0 1120.0 5.17 1240.0 671.0 2.76 5.612 0.9568 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A10 compound treatment 880.0 321.0 1.48 1320.0 751.0 3.09 3.2331 0.9431 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A11 compound treatment 880.0 321.0 1.48 760.0 191.0 0.79 1.6021 0.956 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A12 compound treatment 1440.0 881.0 4.07 2120.0 1550.0 6.39 7.3914 0.9762 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A13 mock treatment 680.0 121.0 0.56 640.0 70.7 0.29 0.5997 0.9542 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A14 mock treatment 680.0 121.0 0.56 680.0 111.0 0.46 0.7162 0.995 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A15 compound treatment 840.0 281.0 1.3 720.0 151.0 0.62 1.355 0.9432 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A16 compound treatment 1000.0 441.0 2.03 1080.0 511.0 2.1 2.9259 0.9999 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A17 compound treatment 1640.0 1080.0 4.99 1280.0 711.0 2.93 5.5979 0.9677 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A18 compound treatment 1600.0 1040.0 4.8 1120.0 551.0 2.27 5.0013 0.9413 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A19 compound treatment 5280.0 4720.0 21.8 4600.0 4030.0 16.6 27.1513 0.991 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A20 compound treatment 520.0 -39.4 -0.18 1240.0 671.0 2.76 1.8248 0.6592 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A21 compound treatment 800.0 241.0 1.11 720.0 151.0 0.62 1.2244 0.9621 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A22 compound treatment 3960.0 3400.0 15.7 3080.0 2510.0 10.34 18.4148 0.9795 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A23 compound treatment 960.0 401.0 1.85 1080.0 511.0 2.1 2.7953 0.9979 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 A24 compound treatment 1720.0 1160.0 5.36 2080.0 1510.0 6.22 8.1891 0.9972 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B01 compound treatment 3680.0 3120.0 14.41 2360.0 1790.0 7.38 15.4036 0.9516 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B02 compound treatment 560.0 0.635 0.0 640.0 70.7 0.29 0.2079 0.7142 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B03 compound treatment 560.0 0.635 0.0 480.0 -89.3 -0.37 -0.2581 -0.7015 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B04 compound treatment 240.0 -319.0 -1.47 560.0 -9.33 -0.04 -1.0699 -0.7253 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B05 compound treatment 480.0 -79.4 -0.37 1000.0 431.0 1.77 0.9952 0.5494 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B06 compound treatment 400.0 -159.0 -0.74 760.0 191.0 0.79 0.035 0.0325 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B07 compound treatment 600.0 40.6 0.19 640.0 70.7 0.29 0.3385 0.9774 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B08 compound treatment 520.0 -39.4 -0.18 440.0 -129.0 -0.53 -0.5052 -0.8976 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B09 compound treatment 920.0 361.0 1.67 600.0 30.7 0.13 1.2667 0.7586 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B10 compound treatment 560.0 0.635 0.0 400.0 -169.0 -0.7 -0.4911 -0.7041 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B11 compound treatment 520.0 -39.4 -0.18 800.0 231.0 0.95 0.5433 0.5616 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B12 compound treatment 1000.0 441.0 2.03 720.0 151.0 0.62 1.8774 0.8826 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B13 mock treatment 480.0 -79.4 -0.37 360.0 -209.0 -0.86 -0.8688 -0.9274 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B14 mock treatment 600.0 40.6 0.19 520.0 -49.3 -0.2 -0.011 -0.0398 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B15 compound treatment 640.0 80.6 0.37 600.0 30.7 0.13 0.3526 0.8968 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B16 compound treatment 640.0 80.6 0.37 520.0 -49.3 -0.2 0.1196 0.2819 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B17 compound treatment 600.0 40.6 0.19 520.0 -49.3 -0.2 -0.011 -0.0398 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B18 compound treatment 680.0 121.0 0.56 920.0 351.0 1.44 1.4152 0.9142 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B19 compound treatment 720.0 161.0 0.74 960.0 391.0 1.61 1.6623 0.9382 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B20 compound treatment 520.0 -39.4 -0.18 560.0 -9.33 -0.04 -0.1557 -0.8381 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B21 compound treatment 2040.0 1480.0 6.84 1640.0 1070.0 4.41 7.9523 0.9775 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B22 compound treatment 1440.0 881.0 4.07 1640.0 1070.0 4.41 5.9934 0.9992 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B23 compound treatment 880.0 321.0 1.48 1400.0 831.0 3.42 3.4661 0.9298 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 B24 compound treatment 600.0 40.6 0.19 560.0 -9.33 -0.04 0.1055 0.5508 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C01 compound treatment 400.0 -159.0 -0.74 720.0 151.0 0.62 -0.0815 -0.0847 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C02 compound treatment 480.0 -79.4 -0.37 440.0 -129.0 -0.53 -0.6358 -0.9833 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C03 compound treatment 920.0 361.0 1.67 1400.0 831.0 3.42 3.5967 0.9452 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C04 compound treatment 480.0 -79.4 -0.37 640.0 70.7 0.29 -0.0533 -0.1139 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C05 compound treatment 1080.0 521.0 2.4 1120.0 551.0 2.27 3.3036 0.9996 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C06 compound treatment 2760.0 2200.0 10.16 1840.0 1270.0 5.23 10.8855 0.9524 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C07 compound treatment 1440.0 881.0 4.07 920.0 351.0 1.44 3.8964 0.903 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C08 compound treatment 560.0 0.635 0.0 680.0 111.0 0.46 0.3244 0.7116 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C09 compound treatment 2520.0 1960.0 9.05 3600.0 3030.0 12.48 15.2279 0.9876 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C10 compound treatment 600.0 40.6 0.19 800.0 231.0 0.95 0.8045 0.8307 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C11 mock treatment 520.0 -39.4 -0.18 600.0 30.7 0.13 -0.0392 -0.1771 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C12 mock treatment 680.0 121.0 0.56 1320.0 751.0 3.09 2.5801 0.8213 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C13 compound treatment 880.0 321.0 1.48 800.0 231.0 0.95 1.7186 0.977 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C14 compound treatment 5280.0 4720.0 21.8 3040.0 2470.0 10.18 22.6079 0.9399 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C15 mock treatment 520.0 -39.4 -0.18 560.0 -9.33 -0.04 -0.1557 -0.8381 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C16 mock treatment 600.0 40.6 0.19 520.0 -49.3 -0.2 -0.011 -0.0398 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C17 compound treatment 600.0 40.6 0.19 520.0 -49.3 -0.2 -0.011 -0.0398 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C18 compound treatment 1680.0 1120.0 5.17 1680.0 1110.0 4.57 6.8935 0.9981 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C19 compound treatment 1600.0 1040.0 4.8 1800.0 1230.0 5.07 6.9818 0.9996 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C20 compound treatment 680.0 121.0 0.56 680.0 111.0 0.46 0.7162 0.995 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C21 compound treatment 640.0 80.6 0.37 640.0 70.7 0.29 0.4691 0.9926 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C22 compound treatment 560.0 0.635 0.0 480.0 -89.3 -0.37 -0.2581 -0.7015 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C23 compound treatment 440.0 -119.0 -0.55 840.0 271.0 1.11 0.3986 0.3205 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 C24 compound treatment 640.0 80.6 0.37 600.0 30.7 0.13 0.3526 0.8968 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D01 compound treatment 640.0 80.6 0.37 640.0 70.7 0.29 0.4691 0.9926 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D02 compound treatment 600.0 40.6 0.19 360.0 -209.0 -0.86 -0.477 -0.5406 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D03 compound treatment 840.0 281.0 1.3 480.0 -89.3 -0.37 0.656 0.4871 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D04 compound treatment 760.0 201.0 0.93 480.0 -89.3 -0.37 0.3949 0.3961 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D05 compound treatment 640.0 80.6 0.37 560.0 -9.33 -0.04 0.2361 0.6307 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D06 compound treatment 560.0 0.635 0.0 720.0 151.0 0.62 0.4409 0.7104 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D07 compound treatment 520.0 -39.4 -0.18 720.0 151.0 0.62 0.3103 0.4798 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D08 compound treatment 560.0 0.635 0.0 720.0 151.0 0.62 0.4409 0.7104 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D09 compound treatment 440.0 -119.0 -0.55 960.0 391.0 1.61 0.7481 0.4398 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D10 compound treatment 960.0 401.0 1.85 880.0 311.0 1.28 2.2128 0.9838 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D11 mock treatment 600.0 40.6 0.19 680.0 111.0 0.46 0.455 0.923 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D12 mock treatment 760.0 201.0 0.93 520.0 -49.3 -0.2 0.5114 0.5392 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D13 compound treatment 4280.0 3720.0 17.18 3560.0 2990.0 12.32 20.8575 0.9867 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D14 compound treatment 680.0 121.0 0.56 440.0 -129.0 -0.53 0.0172 0.0223 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D15 mock treatment 600.0 40.6 0.19 560.0 -9.33 -0.04 0.1055 0.5508 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D16 mock treatment 480.0 -79.4 -0.37 600.0 30.7 0.13 -0.1698 -0.4381 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D17 compound treatment 480.0 -79.4 -0.37 720.0 151.0 0.62 0.1797 0.2493 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D18 compound treatment 440.0 -119.0 -0.55 400.0 -169.0 -0.7 -0.8829 -0.9932 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D19 compound treatment 600.0 40.6 0.19 560.0 -9.33 -0.04 0.1055 0.5508 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D20 compound treatment 800.0 241.0 1.11 560.0 -9.33 -0.04 0.7585 0.6822 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D21 compound treatment 680.0 121.0 0.56 760.0 191.0 0.79 0.9492 0.9858 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D22 compound treatment 1280.0 721.0 3.33 1440.0 871.0 3.59 4.8886 0.9993 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D23 compound treatment 1400.0 841.0 3.88 1520.0 951.0 3.92 5.5133 1.0 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 D24 compound treatment 480.0 -79.4 -0.37 680.0 111.0 0.46 0.0632 0.1081 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E01 mock treatment 400.0 -159.0 -0.74 320.0 -249.0 -1.03 -1.2465 -0.9866 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E02 mock treatment 440.0 -119.0 -0.55 680.0 111.0 0.46 -0.0674 -0.0942 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E03 compound treatment 640.0 80.6 0.37 560.0 -9.33 -0.04 0.2361 0.6307 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E04 compound treatment 1640.0 1080.0 4.99 680.0 111.0 0.46 3.8504 0.7685 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E05 compound treatment 1040.0 481.0 2.22 840.0 271.0 1.11 2.3575 0.9493 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E06 compound treatment 1320.0 761.0 3.51 1080.0 511.0 2.1 3.9707 0.9699 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E07 compound treatment 2520.0 1960.0 9.05 1400.0 831.0 3.42 8.8205 0.9114 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E08 compound treatment 720.0 161.0 0.74 720.0 151.0 0.62 0.9633 0.9961 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E09 mock treatment 360.0 -199.0 -0.92 560.0 -9.33 -0.04 -0.6781 -0.736 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E10 mock treatment 400.0 -159.0 -0.74 680.0 111.0 0.46 -0.198 -0.2287 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E11 compound treatment 2080.0 1520.0 7.02 2960.0 2390.0 9.85 11.9274 0.9863 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E12 compound treatment 1640.0 1080.0 4.99 920.0 351.0 1.44 4.5494 0.8758 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E13 compound treatment 3120.0 2560.0 11.82 3960.0 3390.0 13.97 18.2353 0.9966 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E14 compound treatment 800.0 241.0 1.11 960.0 391.0 1.61 1.9234 0.9836 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E15 compound treatment 1920.0 1360.0 6.28 1680.0 1110.0 4.57 7.677 0.9879 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E16 compound treatment 640.0 80.6 0.37 480.0 -89.3 -0.37 0.0031 0.0059 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E17 mock treatment 520.0 -39.4 -0.18 600.0 30.7 0.13 -0.0392 -0.1771 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E18 mock treatment 600.0 40.6 0.19 520.0 -49.3 -0.2 -0.011 -0.0398 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E19 compound treatment 3160.0 2600.0 12.01 2960.0 2390.0 9.85 15.4534 0.9951 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E20 compound treatment 600.0 40.6 0.19 800.0 231.0 0.95 0.8045 0.8307 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E21 compound treatment 920.0 361.0 1.67 920.0 351.0 1.44 2.1987 0.9975 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E22 compound treatment 1760.0 1200.0 5.54 1400.0 831.0 3.42 6.3392 0.9731 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E23 compound treatment 2520.0 1960.0 9.05 2360.0 1790.0 7.38 11.6164 0.9948 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 E24 compound treatment 1480.0 921.0 4.25 2040.0 1470.0 6.06 7.289 0.985 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F01 mock treatment 720.0 161.0 0.74 560.0 -9.33 -0.04 0.4973 0.6696 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F02 mock treatment 480.0 -79.4 -0.37 760.0 191.0 0.79 0.2962 0.3418 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F03 compound treatment 1080.0 521.0 2.4 800.0 231.0 0.95 2.3716 0.9175 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F04 compound treatment 440.0 -119.0 -0.55 600.0 30.7 0.13 -0.3004 -0.5313 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F05 compound treatment 640.0 80.6 0.37 720.0 151.0 0.62 0.7021 0.9701 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F06 compound treatment 520.0 -39.4 -0.18 440.0 -129.0 -0.53 -0.5052 -0.8976 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F07 compound treatment 1640.0 1080.0 4.99 1960.0 1390.0 5.73 7.5784 0.9976 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F08 compound treatment 480.0 -79.4 -0.37 520.0 -49.3 -0.2 -0.4028 -0.9613 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F09 mock treatment 640.0 80.6 0.37 680.0 111.0 0.46 0.5856 0.995 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F10 mock treatment 520.0 -39.4 -0.18 520.0 -49.3 -0.2 -0.2722 -0.9985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F11 compound treatment 640.0 80.6 0.37 520.0 -49.3 -0.2 0.1196 0.2819 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F12 compound treatment 680.0 121.0 0.56 720.0 151.0 0.62 0.8327 0.9985 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F13 compound treatment 8520.0 7960.0 36.76 4920.0 4350.0 17.92 38.6614 0.9455 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F14 compound treatment 1360.0 801.0 3.7 1760.0 1190.0 4.9 6.0817 0.9903 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F15 compound treatment 800.0 241.0 1.11 800.0 231.0 0.95 1.4574 0.997 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F16 compound treatment 720.0 161.0 0.74 680.0 111.0 0.46 0.8468 0.9727 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F17 mock treatment 560.0 0.635 0.0 760.0 191.0 0.79 0.5574 0.7097 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F18 mock treatment 480.0 -79.4 -0.37 440.0 -129.0 -0.53 -0.6358 -0.9833 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F19 compound treatment 1960.0 1400.0 6.47 1600.0 1030.0 4.25 7.5746 0.9792 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F20 compound treatment 600.0 40.6 0.19 720.0 151.0 0.62 0.5715 0.8815 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F21 compound treatment 3440.0 2880.0 13.3 3160.0 2590.0 10.67 16.9501 0.994 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F22 compound treatment 1400.0 841.0 3.88 1840.0 1270.0 5.23 6.4453 0.9892 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F23 compound treatment 640.0 80.6 0.37 840.0 271.0 1.11 1.0516 0.8947 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 F24 compound treatment 760.0 201.0 0.93 1040.0 471.0 1.94 2.0258 0.9429 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G01 compound treatment 1840.0 1280.0 5.91 2040.0 1470.0 6.06 8.4643 0.9999 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G02 compound treatment 1360.0 801.0 3.7 2000.0 1430.0 5.89 6.7807 0.9748 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G03 mock treatment 560.0 0.635 0.0 560.0 -9.33 -0.04 -0.0251 -0.6513 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G04 mock treatment 640.0 80.6 0.37 480.0 -89.3 -0.37 0.0031 0.0059 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G05 compound treatment 1560.0 1000.0 4.62 1760.0 1190.0 4.9 6.7347 0.9996 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G06 compound treatment 8720.0 8160.0 37.68 4440.0 3870.0 15.94 37.9164 0.9268 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G07 compound treatment 680.0 121.0 0.56 520.0 -49.3 -0.2 0.2502 0.4219 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G08 compound treatment 680.0 121.0 0.56 1160.0 591.0 2.43 2.1142 0.8471 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G09 compound treatment 4680.0 4120.0 19.03 2680.0 2110.0 8.69 19.6005 0.937 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G10 compound treatment 680.0 121.0 0.56 720.0 151.0 0.62 0.8327 0.9985 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G11 compound treatment 4240.0 3680.0 16.99 3760.0 3190.0 13.14 21.3094 0.9919 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G12 compound treatment 560.0 0.635 0.0 520.0 -49.3 -0.2 -0.1416 -0.6968 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G13 compound treatment 3760.0 3200.0 14.78 3680.0 3110.0 12.81 19.5093 0.9975 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G14 compound treatment 1560.0 1000.0 4.62 1000.0 431.0 1.77 4.5212 0.9136 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G15 compound treatment 1000.0 441.0 2.03 720.0 151.0 0.62 1.8774 0.8826 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G16 compound treatment 440.0 -119.0 -0.55 440.0 -129.0 -0.53 -0.7664 -0.9999 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G17 compound treatment 2480.0 1920.0 8.87 1920.0 1350.0 5.56 10.2043 0.9748 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G18 compound treatment 2200.0 1640.0 7.58 1160.0 591.0 2.43 7.0767 0.8895 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G19 mock treatment 640.0 80.6 0.37 600.0 30.7 0.13 0.3526 0.8968 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G20 mock treatment 560.0 0.635 0.0 480.0 -89.3 -0.37 -0.2581 -0.7015 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G21 compound treatment 5680.0 5120.0 23.64 5880.0 5310.0 21.87 32.1852 0.9992 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G22 compound treatment 480.0 -79.4 -0.37 560.0 -9.33 -0.04 -0.2863 -0.777 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G23 compound treatment 2520.0 1960.0 9.05 2760.0 2190.0 9.02 12.7814 1.0 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 G24 compound treatment 960.0 401.0 1.85 800.0 231.0 0.95 1.9798 0.9521 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H01 compound treatment 440.0 -119.0 -0.55 520.0 -49.3 -0.2 -0.5334 -0.9081 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H02 compound treatment 640.0 80.6 0.37 560.0 -9.33 -0.04 0.2361 0.6307 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H03 mock treatment 480.0 -79.4 -0.37 1000.0 431.0 1.77 0.9952 0.5494 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H04 mock treatment 400.0 -159.0 -0.74 480.0 -89.3 -0.37 -0.7805 -0.9487 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H05 compound treatment 720.0 161.0 0.74 520.0 -49.3 -0.2 0.3808 0.4951 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H06 compound treatment 520.0 -39.4 -0.18 520.0 -49.3 -0.2 -0.2722 -0.9985 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H07 compound treatment 960.0 401.0 1.85 880.0 311.0 1.28 2.2128 0.9838 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H08 compound treatment 520.0 -39.4 -0.18 720.0 151.0 0.62 0.3103 0.4798 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H09 compound treatment 920.0 361.0 1.67 640.0 70.7 0.29 1.3832 0.8183 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H10 compound treatment 640.0 80.6 0.37 560.0 -9.33 -0.04 0.2361 0.6307 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H11 compound treatment 640.0 80.6 0.37 840.0 271.0 1.11 1.0516 0.8947 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H12 compound treatment 1080.0 521.0 2.4 760.0 191.0 0.79 2.2551 0.8917 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H13 compound treatment 920.0 361.0 1.67 680.0 111.0 0.46 1.4997 0.8687 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H14 compound treatment 1680.0 1120.0 5.17 720.0 151.0 0.62 4.0975 0.7863 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H15 compound treatment 3600.0 3040.0 14.04 1680.0 1110.0 4.57 13.162 0.8914 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H16 compound treatment 1000.0 441.0 2.03 520.0 -49.3 -0.2 1.2949 0.6333 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H17 compound treatment 3480.0 2920.0 13.49 2200.0 1630.0 6.72 14.2847 0.9482 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H18 compound treatment 840.0 281.0 1.3 600.0 30.7 0.13 1.0055 0.7724 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H19 mock treatment 560.0 0.635 0.0 840.0 271.0 1.11 0.7904 0.709 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H20 mock treatment 520.0 -39.4 -0.18 440.0 -129.0 -0.53 -0.5052 -0.8976 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H21 compound treatment 600.0 40.6 0.19 560.0 -9.33 -0.04 0.1055 0.5508 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H22 compound treatment 920.0 361.0 1.67 1280.0 711.0 2.93 3.2472 0.9643 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H23 compound treatment 840.0 281.0 1.3 880.0 311.0 1.28 1.821 1.0 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 H24 compound treatment 560.0 0.635 0.0 520.0 -49.3 -0.2 -0.1416 -0.6968 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I01 compound treatment 1040.0 481.0 2.22 1640.0 1070.0 4.41 4.6875 0.9495 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I02 compound treatment 680.0 121.0 0.56 800.0 231.0 0.95 1.0657 0.9676 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I03 compound treatment 560.0 0.635 0.0 440.0 -129.0 -0.53 -0.3746 -0.7032 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I04 compound treatment 2440.0 1880.0 8.68 1520.0 951.0 3.92 8.9088 0.9353 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I05 mock treatment 520.0 -39.4 -0.18 680.0 111.0 0.46 0.1938 0.3949 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I06 mock treatment 560.0 0.635 0.0 400.0 -169.0 -0.7 -0.4911 -0.7041 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I07 compound treatment 520.0 -39.4 -0.18 520.0 -49.3 -0.2 -0.2722 -0.9985 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I08 compound treatment 600.0 40.6 0.19 400.0 -169.0 -0.7 -0.3605 -0.4991 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I09 compound treatment 720.0 161.0 0.74 800.0 231.0 0.95 1.1963 0.9925 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I10 compound treatment 1480.0 921.0 4.25 1920.0 1350.0 5.56 6.9395 0.9912 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I11 compound treatment 4400.0 3840.0 17.73 3640.0 3070.0 12.65 21.4823 0.9863 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I12 compound treatment 1960.0 1400.0 6.47 1960.0 1390.0 5.73 8.6231 0.9982 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I13 compound treatment 3560.0 3000.0 13.85 2840.0 2270.0 9.35 16.4099 0.9817 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I14 compound treatment 1120.0 561.0 2.59 800.0 231.0 0.95 2.5022 0.9074 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I15 compound treatment 2440.0 1880.0 8.68 2600.0 2030.0 8.36 12.0542 0.9998 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I16 compound treatment 3160.0 2600.0 12.01 2880.0 2310.0 9.52 15.2204 0.9934 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I17 compound treatment 3600.0 3040.0 14.04 2640.0 2070.0 8.53 15.958 0.9715 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I18 compound treatment 2480.0 1920.0 8.87 1640.0 1070.0 4.41 9.3889 0.948 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I19 compound treatment 1920.0 1360.0 6.28 1560.0 991.0 4.08 7.3275 0.9782 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I20 compound treatment 600.0 40.6 0.19 600.0 30.7 0.13 0.222 0.9815 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I21 mock treatment 840.0 281.0 1.3 600.0 30.7 0.13 1.0055 0.7724 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I22 mock treatment 440.0 -119.0 -0.55 520.0 -49.3 -0.2 -0.5334 -0.9081 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I23 compound treatment 3880.0 3320.0 15.33 4520.0 3950.0 16.27 22.3476 0.9996 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 I24 compound treatment 3280.0 2720.0 12.56 3320.0 2750.0 11.33 16.8937 0.9987 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J01 compound treatment 1400.0 841.0 3.88 1400.0 831.0 3.42 5.1638 0.998 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J02 compound treatment 1920.0 1360.0 6.28 2000.0 1430.0 5.89 8.609 0.9995 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J03 compound treatment 680.0 121.0 0.56 680.0 111.0 0.46 0.7162 0.995 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J04 compound treatment 640.0 80.6 0.37 720.0 151.0 0.62 0.7021 0.9701 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J05 mock treatment 680.0 121.0 0.56 600.0 30.7 0.13 0.4832 0.846 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J06 mock treatment 440.0 -119.0 -0.55 560.0 -9.33 -0.04 -0.4169 -0.7546 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J07 compound treatment 520.0 -39.4 -0.18 520.0 -49.3 -0.2 -0.2722 -0.9985 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J08 compound treatment 640.0 80.6 0.37 800.0 231.0 0.95 0.9351 0.9164 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J09 compound treatment 760.0 201.0 0.93 1040.0 471.0 1.94 2.0258 0.9429 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J10 compound treatment 1000.0 441.0 2.03 600.0 30.7 0.13 1.5279 0.7496 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J11 compound treatment 1680.0 1120.0 5.17 1920.0 1350.0 5.56 7.5925 0.9993 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J12 compound treatment 600.0 40.6 0.19 800.0 231.0 0.95 0.8045 0.8307 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J13 compound treatment 760.0 201.0 0.93 640.0 70.7 0.29 0.8609 0.8865 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J14 compound treatment 480.0 -79.4 -0.37 720.0 151.0 0.62 0.1797 0.2493 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J15 compound treatment 600.0 40.6 0.19 680.0 111.0 0.46 0.455 0.923 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J16 compound treatment 2240.0 1680.0 7.76 2040.0 1470.0 6.06 9.7703 0.9925 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J17 compound treatment 1120.0 561.0 2.59 840.0 271.0 1.11 2.6187 0.9291 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J18 compound treatment 960.0 401.0 1.85 840.0 271.0 1.11 2.0963 0.9706 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J19 compound treatment 1000.0 441.0 2.03 880.0 311.0 1.28 2.3434 0.975 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J20 compound treatment 960.0 401.0 1.85 1040.0 471.0 1.94 2.6788 0.9997 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J21 mock treatment 640.0 80.6 0.37 960.0 391.0 1.61 1.4011 0.8483 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J22 mock treatment 600.0 40.6 0.19 720.0 151.0 0.62 0.5715 0.8815 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J23 compound treatment 760.0 201.0 0.93 640.0 70.7 0.29 0.8609 0.8865 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 J24 compound treatment 3400.0 2840.0 13.12 2320.0 1750.0 7.21 14.373 0.9603 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K01 compound treatment 1240.0 681.0 3.14 1440.0 871.0 3.59 4.758 0.9978 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K02 compound treatment 2320.0 1760.0 8.13 2800.0 2230.0 9.19 12.2449 0.9981 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K03 compound treatment 1320.0 761.0 3.51 640.0 70.7 0.29 2.6892 0.7631 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K04 compound treatment 920.0 361.0 1.67 880.0 311.0 1.28 2.0822 0.9915 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K05 compound treatment 800.0 241.0 1.11 560.0 -9.33 -0.04 0.7585 0.6822 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K06 compound treatment 1920.0 1360.0 6.28 2080.0 1510.0 6.22 8.842 1.0 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K07 mock treatment 400.0 -159.0 -0.74 520.0 -49.3 -0.2 -0.664 -0.8698 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K08 mock treatment 720.0 161.0 0.74 400.0 -169.0 -0.7 0.0313 0.0307 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K09 compound treatment 1000.0 441.0 2.03 840.0 271.0 1.11 2.2269 0.9599 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K10 compound treatment 1600.0 1040.0 4.8 2040.0 1470.0 6.06 7.6808 0.9934 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K11 compound treatment 6120.0 5560.0 25.67 4520.0 3950.0 16.27 29.6608 0.9758 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K12 compound treatment 1200.0 641.0 2.96 920.0 351.0 1.44 3.1129 0.9457 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K13 compound treatment 1720.0 1160.0 5.36 1560.0 991.0 4.08 6.6746 0.991 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K14 compound treatment 560.0 0.635 0.0 880.0 311.0 1.28 0.9069 0.7087 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K15 mock treatment 1000.0 441.0 2.03 560.0 -9.33 -0.04 1.4114 0.6936 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K16 mock treatment 520.0 -39.4 -0.18 520.0 -49.3 -0.2 -0.2722 -0.9985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K17 compound treatment 5320.0 4760.0 21.98 4160.0 3590.0 14.79 26.0004 0.9814 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K18 compound treatment 3880.0 3320.0 15.33 4040.0 3470.0 14.3 20.9496 0.9994 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K19 compound treatment 1120.0 561.0 2.59 760.0 191.0 0.79 2.3857 0.8819 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K20 compound treatment 2240.0 1680.0 7.76 2320.0 1750.0 7.21 10.5858 0.9993 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K21 compound treatment 1040.0 481.0 2.22 1440.0 871.0 3.59 4.105 0.9734 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K22 compound treatment 1600.0 1040.0 4.8 560.0 -9.33 -0.04 3.3703 0.7014 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K23 mock treatment 680.0 121.0 0.56 760.0 191.0 0.79 0.9492 0.9858 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 K24 mock treatment 480.0 -79.4 -0.37 560.0 -9.33 -0.04 -0.2863 -0.777 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L01 compound treatment 640.0 80.6 0.37 760.0 191.0 0.79 0.8186 0.9418 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L02 compound treatment 520.0 -39.4 -0.18 520.0 -49.3 -0.2 -0.2722 -0.9985 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L03 compound treatment 600.0 40.6 0.19 880.0 311.0 1.28 1.0375 0.8022 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L04 compound treatment 600.0 40.6 0.19 560.0 -9.33 -0.04 0.1055 0.5508 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L05 compound treatment 800.0 241.0 1.11 440.0 -129.0 -0.53 0.409 0.3319 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L06 compound treatment 480.0 -79.4 -0.37 360.0 -209.0 -0.86 -0.8688 -0.9274 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L07 mock treatment 680.0 121.0 0.56 360.0 -209.0 -0.86 -0.2158 -0.2103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L08 mock treatment 360.0 -199.0 -0.92 520.0 -49.3 -0.2 -0.7946 -0.8429 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L09 compound treatment 760.0 201.0 0.93 840.0 271.0 1.11 1.4434 0.9958 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L10 compound treatment 1440.0 881.0 4.07 960.0 391.0 1.61 4.0129 0.9177 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L11 compound treatment 1120.0 561.0 2.59 520.0 -49.3 -0.2 1.6867 0.6496 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L12 compound treatment 320.0 -239.0 -1.11 520.0 -49.3 -0.2 -0.9252 -0.8233 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L13 compound treatment 4520.0 3960.0 18.29 3640.0 3070.0 12.65 21.8741 0.9838 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L14 compound treatment 520.0 -39.4 -0.18 600.0 30.7 0.13 -0.0392 -0.1771 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L15 mock treatment 680.0 121.0 0.56 680.0 111.0 0.46 0.7162 0.995 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L16 mock treatment 600.0 40.6 0.19 680.0 111.0 0.46 0.455 0.923 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L17 compound treatment 1080.0 521.0 2.4 520.0 -49.3 -0.2 1.5561 0.645 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L18 compound treatment 440.0 -119.0 -0.55 400.0 -169.0 -0.7 -0.8829 -0.9932 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L19 compound treatment 2560.0 2000.0 9.24 1600.0 1030.0 4.25 9.5335 0.9378 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L20 compound treatment 600.0 40.6 0.19 600.0 30.7 0.13 0.222 0.9815 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L21 compound treatment 880.0 321.0 1.48 1200.0 631.0 2.6 2.8836 0.9645 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L22 compound treatment 2080.0 1520.0 7.02 720.0 151.0 0.62 5.4034 0.7666 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L23 mock treatment 880.0 321.0 1.48 560.0 -9.33 -0.04 1.0196 0.6885 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 L24 mock treatment 680.0 121.0 0.56 320.0 -249.0 -1.03 -0.3323 -0.2845 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M01 compound treatment 2160.0 1600.0 7.39 1360.0 791.0 3.26 7.5286 0.9322 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M02 compound treatment 5320.0 4760.0 21.98 5440.0 4870.0 20.06 29.7284 0.999 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M03 compound treatment 1480.0 921.0 4.25 1640.0 1070.0 4.41 6.124 0.9998 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M04 compound treatment 3200.0 2640.0 12.19 2280.0 1710.0 7.05 13.6035 0.966 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M05 compound treatment 2000.0 1440.0 6.65 1920.0 1350.0 5.56 8.6372 0.9961 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M06 compound treatment 2200.0 1640.0 7.58 1600.0 1030.0 4.25 8.3582 0.9625 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M07 compound treatment 4280.0 3720.0 17.18 4400.0 3830.0 15.78 23.304 0.9991 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M08 compound treatment 4440.0 3880.0 17.92 3360.0 2790.0 11.49 20.7974 0.977 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M09 mock treatment 400.0 -159.0 -0.74 520.0 -49.3 -0.2 -0.664 -0.8698 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M10 mock treatment 480.0 -79.4 -0.37 760.0 191.0 0.79 0.2962 0.3418 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M11 compound treatment 680.0 121.0 0.56 440.0 -129.0 -0.53 0.0172 0.0223 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M12 compound treatment 560.0 0.635 0.0 440.0 -129.0 -0.53 -0.3746 -0.7032 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M13 mock treatment 480.0 -79.4 -0.37 520.0 -49.3 -0.2 -0.4028 -0.9613 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M14 mock treatment 440.0 -119.0 -0.55 560.0 -9.33 -0.04 -0.4169 -0.7546 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M15 compound treatment 3800.0 3240.0 14.96 3360.0 2790.0 11.49 18.7079 0.9915 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M16 compound treatment 840.0 281.0 1.3 1080.0 511.0 2.1 2.4035 0.9729 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M17 compound treatment 3480.0 2920.0 13.49 3120.0 2550.0 10.51 16.9642 0.9924 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M18 compound treatment 1680.0 1120.0 5.17 2360.0 1790.0 7.38 8.874 0.985 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M19 compound treatment 560.0 0.635 0.0 920.0 351.0 1.44 1.0234 0.7085 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M20 compound treatment 1120.0 561.0 2.59 760.0 191.0 0.79 2.3857 0.8819 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M21 compound treatment 1600.0 1040.0 4.8 1520.0 951.0 3.92 6.1663 0.9948 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M22 compound treatment 680.0 121.0 0.56 480.0 -89.3 -0.37 0.1337 0.2002 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M23 compound treatment 1200.0 641.0 2.96 1240.0 671.0 2.76 4.0449 0.9994 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 M24 compound treatment 1480.0 921.0 4.25 920.0 351.0 1.44 4.027 0.897 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N01 compound treatment 440.0 -119.0 -0.55 360.0 -209.0 -0.86 -0.9994 -0.9766 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N02 compound treatment 760.0 201.0 0.93 640.0 70.7 0.29 0.8609 0.8865 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N03 compound treatment 920.0 361.0 1.67 520.0 -49.3 -0.2 1.0337 0.6162 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N04 compound treatment 640.0 80.6 0.37 600.0 30.7 0.13 0.3526 0.8968 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N05 compound treatment 3400.0 2840.0 13.12 3280.0 2710.0 11.16 17.169 0.9968 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N06 compound treatment 440.0 -119.0 -0.55 760.0 191.0 0.79 0.1656 0.1726 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N07 compound treatment 880.0 321.0 1.48 800.0 231.0 0.95 1.7186 0.977 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N08 compound treatment 720.0 161.0 0.74 920.0 351.0 1.44 1.5458 0.952 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N09 mock treatment 520.0 -39.4 -0.18 680.0 111.0 0.46 0.1938 0.3949 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N10 mock treatment 480.0 -79.4 -0.37 440.0 -129.0 -0.53 -0.6358 -0.9833 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N11 compound treatment 1680.0 1120.0 5.17 840.0 271.0 1.11 4.447 0.8402 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N12 compound treatment 840.0 281.0 1.3 680.0 111.0 0.46 1.2385 0.9017 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N13 mock treatment 560.0 0.635 0.0 720.0 151.0 0.62 0.4409 0.7104 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N14 mock treatment 680.0 121.0 0.56 480.0 -89.3 -0.37 0.1337 0.2002 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N15 compound treatment 3080.0 2520.0 11.64 1520.0 951.0 3.92 10.9983 0.8957 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N16 compound treatment 760.0 201.0 0.93 640.0 70.7 0.29 0.8609 0.8865 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N17 compound treatment 840.0 281.0 1.3 520.0 -49.3 -0.2 0.7725 0.589 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N18 compound treatment 720.0 161.0 0.74 1160.0 591.0 2.43 2.2447 0.8826 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N19 compound treatment 1000.0 441.0 2.03 720.0 151.0 0.62 1.8774 0.8826 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N20 compound treatment 480.0 -79.4 -0.37 640.0 70.7 0.29 -0.0533 -0.1139 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N21 compound treatment 880.0 321.0 1.48 600.0 30.7 0.13 1.1361 0.7647 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N22 compound treatment 2440.0 1880.0 8.68 1720.0 1150.0 4.74 9.4913 0.9594 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N23 compound treatment 760.0 201.0 0.93 1240.0 671.0 2.76 2.6083 0.8952 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 N24 compound treatment 640.0 80.6 0.37 440.0 -129.0 -0.53 -0.1134 -0.1745 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O01 compound treatment 480.0 -79.4 -0.37 440.0 -129.0 -0.53 -0.6358 -0.9833 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O02 compound treatment 440.0 -119.0 -0.55 560.0 -9.33 -0.04 -0.4169 -0.7546 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O03 compound treatment 1760.0 1200.0 5.54 1360.0 791.0 3.26 6.2227 0.9679 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O04 compound treatment 840.0 281.0 1.3 1320.0 751.0 3.09 3.1025 0.9255 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O05 compound treatment 4080.0 3520.0 16.26 4080.0 3510.0 14.46 21.719 0.9983 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O06 compound treatment 4920.0 4360.0 20.13 3760.0 3190.0 13.14 23.5295 0.9786 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O07 compound treatment 2360.0 1800.0 8.31 1880.0 1310.0 5.4 9.6961 0.9781 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O08 compound treatment 1240.0 681.0 3.14 1240.0 671.0 2.76 4.1755 0.9979 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O09 compound treatment 2160.0 1600.0 7.39 2280.0 1710.0 7.05 10.2081 0.9997 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O10 compound treatment 1240.0 681.0 3.14 1360.0 791.0 3.26 4.525 0.9998 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O11 mock treatment 600.0 40.6 0.19 600.0 30.7 0.13 0.222 0.9815 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O12 mock treatment 480.0 -79.4 -0.37 480.0 -89.3 -0.37 -0.5193 -1.0 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O13 compound treatment 2080.0 1520.0 7.02 1680.0 1110.0 4.57 8.1994 0.9785 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O14 compound treatment 4280.0 3720.0 17.18 2360.0 1790.0 7.38 17.3626 0.9287 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O15 compound treatment 2400.0 1840.0 8.5 2360.0 1790.0 7.38 11.2246 0.9975 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O16 compound treatment 640.0 80.6 0.37 840.0 271.0 1.11 1.0516 0.8947 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O17 compound treatment 1680.0 1120.0 5.17 2680.0 2110.0 8.69 9.806 0.9693 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O18 compound treatment 1360.0 801.0 3.7 1120.0 551.0 2.27 4.2177 0.9725 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O19 compound treatment 2560.0 2000.0 9.24 2120.0 1550.0 6.39 11.048 0.9838 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O20 compound treatment 1600.0 1040.0 4.8 2160.0 1590.0 6.55 8.0303 0.9884 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O21 compound treatment 1200.0 641.0 2.96 680.0 111.0 0.46 2.4139 0.8066 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O22 compound treatment 3160.0 2600.0 12.01 3960.0 3390.0 13.97 18.3659 0.9972 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O23 compound treatment 6160.0 5600.0 25.86 7280.0 6710.0 27.64 37.8298 0.9994 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 O24 compound treatment 480.0 -79.4 -0.37 400.0 -169.0 -0.7 -0.7523 -0.9549 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P01 compound treatment 400.0 -159.0 -0.74 1280.0 711.0 2.93 1.5495 0.5134 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P02 compound treatment 440.0 -119.0 -0.55 640.0 70.7 0.29 -0.1839 -0.295 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P03 compound treatment 1160.0 601.0 2.77 1120.0 551.0 2.27 3.5648 0.995 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P04 compound treatment 680.0 121.0 0.56 720.0 151.0 0.62 0.8327 0.9985 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P05 compound treatment 2800.0 2240.0 10.35 1800.0 1230.0 5.07 10.8996 0.9461 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P06 compound treatment 800.0 241.0 1.11 800.0 231.0 0.95 1.4574 0.997 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P07 compound treatment 920.0 361.0 1.67 1040.0 471.0 1.94 2.5482 0.9971 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P08 compound treatment 520.0 -39.4 -0.18 760.0 191.0 0.79 0.4268 0.5295 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P09 compound treatment 1240.0 681.0 3.14 880.0 311.0 1.28 3.127 0.9216 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P10 compound treatment 2200.0 1640.0 7.58 1400.0 831.0 3.42 7.7757 0.9355 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P11 mock treatment 520.0 -39.4 -0.18 1200.0 631.0 2.6 1.7083 0.656 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P12 mock treatment 520.0 -39.4 -0.18 680.0 111.0 0.46 0.1938 0.3949 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P13 compound treatment 760.0 201.0 0.93 720.0 151.0 0.62 1.0939 0.981 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P14 compound treatment 400.0 -159.0 -0.74 600.0 30.7 0.13 -0.431 -0.5773 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P15 compound treatment 1080.0 521.0 2.4 1120.0 551.0 2.27 3.3036 0.9996 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P16 compound treatment 840.0 281.0 1.3 520.0 -49.3 -0.2 0.7725 0.589 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P17 compound treatment 840.0 281.0 1.3 1080.0 511.0 2.1 2.4035 0.9729 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P18 compound treatment 1320.0 761.0 3.51 1720.0 1150.0 4.74 5.8346 0.9891 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P19 compound treatment 2160.0 1600.0 7.39 1240.0 671.0 2.76 7.1791 0.9099 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P20 compound treatment 840.0 281.0 1.3 920.0 351.0 1.44 1.9375 0.9985 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P21 compound treatment 2240.0 1680.0 7.76 1920.0 1350.0 5.56 9.4208 0.9867 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P22 compound treatment 1240.0 681.0 3.14 1400.0 831.0 3.42 4.6415 0.9991 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P23 compound treatment 1520.0 961.0 4.44 2320.0 1750.0 7.21 8.2351 0.9728 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2102 P24 compound treatment 1240.0 681.0 3.14 840.0 271.0 1.11 3.0105 0.9028 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A01 compound treatment 1400.0 799.0 3.69 1480.0 851.0 3.51 5.0865 0.9997 3070297 PK04_103001 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A02 compound treatment 1000.0 399.0 1.84 2520.0 1890.0 7.79 6.8095 0.8508 3189402 PK04_103002 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A03 compound treatment 840.0 239.0 1.1 920.0 291.0 1.2 1.6272 0.9991 3070298 PK04_103003 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A04 compound treatment 1440.0 839.0 3.87 1680.0 1050.0 4.33 5.7996 0.9984 3189403 PK04_103004 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A05 compound treatment 1120.0 519.0 2.39 1000.0 371.0 1.53 2.7743 0.9765 3070299 PK04_103005 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A06 compound treatment 1000.0 399.0 1.84 1520.0 891.0 3.67 3.897 0.9491 3189404 PK04_103006 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A07 compound treatment 800.0 199.0 0.92 720.0 91.1 0.38 0.9141 0.9223 3070300 PK04_103007 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A08 compound treatment 1480.0 879.0 4.06 1400.0 771.0 3.18 5.1147 0.9927 3189405 PK04_103008 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A09 compound treatment 800.0 199.0 0.92 680.0 51.1 0.21 0.7976 0.8474 3189406 PK04_103009 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A10 compound treatment 600.0 -1.33 -0.01 1240.0 611.0 2.52 1.7756 0.7054 3070355 PK04_103010 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A11 compound treatment 880.0 279.0 1.29 640.0 11.1 0.05 0.9423 0.7319 3189407 PK04_103011 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1cccc(OCCO)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A12 compound treatment 1200.0 599.0 2.76 720.0 91.1 0.38 2.22 0.7958 3189408 PK04_103012 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A13 mock treatment 520.0 -81.3 -0.38 960.0 331.0 1.36 0.6989 0.494 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A14 mock treatment 640.0 38.7 0.18 600.0 -28.9 -0.12 0.0422 0.1968 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A15 compound treatment 2120.0 1520.0 7.01 1760.0 1130.0 4.66 8.2526 0.9803 3070356 PK04_103013 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A16 compound treatment 880.0 279.0 1.29 560.0 -68.9 -0.28 0.7093 0.5383 3189409 PK04_103014 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A17 compound treatment 2280.0 1680.0 7.75 1840.0 1210.0 4.99 9.008 0.9773 3070357 PK04_103015 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A18 compound treatment 2640.0 2040.0 9.41 3400.0 2770.0 11.41 14.7268 0.9954 3189410 PK04_103016 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A19 compound treatment 2000.0 1400.0 6.46 1240.0 611.0 2.52 6.3464 0.9156 3070358 PK04_103017 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccccc1OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A20 compound treatment 2680.0 2080.0 9.6 2960.0 2330.0 9.6 13.5759 1.0 3189411 PK04_103018 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A21 compound treatment 640.0 38.7 0.18 760.0 131.0 0.54 0.5082 0.8933 3070359 PK04_103019 CCCCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A22 compound treatment 2120.0 1520.0 7.01 3480.0 2850.0 11.74 13.2621 0.9696 3189412 PK04_103020 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A23 compound treatment 640.0 38.7 0.18 960.0 331.0 1.36 1.0907 0.7929 3070360 PK04_103021 CC(C)C(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 A24 compound treatment 3080.0 2480.0 11.44 1800.0 1170.0 4.82 11.5034 0.9262 3189413 PK04_103022 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B01 compound treatment 1640.0 1040.0 4.8 760.0 131.0 0.54 3.773 0.7818 3189525 PK04_103023 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B02 compound treatment 560.0 -41.3 -0.19 560.0 -68.9 -0.28 -0.3355 -0.9814 3070361 PK04_103024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B03 compound treatment 720.0 119.0 0.55 1080.0 451.0 1.86 1.7014 0.8782 3189526 PK04_103025 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B04 compound treatment 440.0 -161.0 -0.74 1120.0 491.0 2.02 0.9037 0.4192 3189527 PK04_103026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B05 compound treatment 720.0 119.0 0.55 760.0 131.0 0.54 0.7694 1.0 3070362 PK04_103027 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B06 compound treatment 840.0 239.0 1.1 520.0 -109.0 -0.45 0.4622 0.3885 3189528 PK04_103028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B07 compound treatment 1080.0 479.0 2.21 960.0 331.0 1.36 2.5272 0.9731 3070363 PK04_103029 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B08 compound treatment 560.0 -41.3 -0.19 600.0 -28.9 -0.12 -0.219 -0.974 3189529 PK04_103030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B09 compound treatment 960.0 359.0 1.66 920.0 291.0 1.2 2.0189 0.9874 3189530 PK04_103031 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B10 compound treatment 640.0 38.7 0.18 560.0 -68.9 -0.28 -0.0743 -0.2217 3070364 PK04_103032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B11 compound treatment 2800.0 2200.0 10.15 1880.0 1250.0 5.15 10.8222 0.9506 3189531 PK04_103033 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B12 compound treatment 1080.0 479.0 2.21 1360.0 731.0 3.01 3.6922 0.9884 3189532 PK04_103034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B13 mock treatment 680.0 78.7 0.36 640.0 11.1 0.05 0.2893 0.7902 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B14 mock treatment 520.0 -81.3 -0.38 560.0 -68.9 -0.28 -0.4661 -0.9904 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B15 compound treatment 1880.0 1280.0 5.9 2280.0 1650.0 6.8 8.9836 0.9975 3070365 PK04_103035 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B16 compound treatment 1960.0 1360.0 6.27 1440.0 811.0 3.34 6.7983 0.9565 3189533 PK04_103036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B17 compound treatment 1080.0 479.0 2.21 1040.0 411.0 1.69 2.7602 0.9914 3070366 PK04_103037 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B18 compound treatment 560.0 -41.3 -0.19 760.0 131.0 0.54 0.247 0.4312 3189534 PK04_103038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B19 compound treatment 640.0 38.7 0.18 640.0 11.1 0.05 0.1587 0.8609 3189535 PK04_103039 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B20 compound treatment 480.0 -121.0 -0.56 760.0 131.0 0.54 -0.0142 -0.0182 3070367 PK04_103040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B21 compound treatment 640.0 38.7 0.18 640.0 11.1 0.05 0.1587 0.8609 3189536 PK04_103041 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B22 compound treatment 840.0 239.0 1.1 1040.0 411.0 1.69 1.9767 0.9783 3189537 PK04_103042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B23 compound treatment 2720.0 2120.0 9.78 2840.0 2210.0 9.11 13.357 0.9994 3070368 PK04_103043 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 B24 compound treatment 800.0 199.0 0.92 680.0 51.1 0.21 0.7976 0.8474 3189538 PK04_103044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C01 compound treatment 600.0 -1.33 -0.01 600.0 -28.9 -0.12 -0.0884 -0.7427 3070369 PK04_103045 COCC(=C)C(=O)CC[C@H](OC(=O)C)c1ccc(CO)o1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C02 compound treatment 760.0 159.0 0.73 1160.0 531.0 2.19 2.065 0.895 3189539 PK04_103046 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C03 compound treatment 520.0 -81.3 -0.38 600.0 -28.9 -0.12 -0.3496 -0.8875 3189540 PK04_103047 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C04 compound treatment 920.0 319.0 1.47 1160.0 531.0 2.19 2.5873 0.9814 3070370 PK04_103048 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C05 compound treatment 600.0 -1.33 -0.01 840.0 211.0 0.87 0.6106 0.7021 3189541 PK04_103049 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C06 compound treatment 640.0 38.7 0.18 600.0 -28.9 -0.12 0.0422 0.1968 3189542 PK04_103050 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C07 compound treatment 1120.0 519.0 2.39 800.0 171.0 0.7 2.1918 0.878 3070371 PK04_103051 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C08 compound treatment 960.0 359.0 1.66 440.0 -189.0 -0.78 0.621 0.3394 3189543 PK04_103052 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C09 compound treatment 760.0 159.0 0.73 600.0 -28.9 -0.12 0.434 0.5848 3070372 PK04_103053 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C10 compound treatment 760.0 159.0 0.73 520.0 -109.0 -0.45 0.201 0.234 3189544 PK04_103054 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C11 mock treatment 680.0 78.7 0.36 520.0 -109.0 -0.45 -0.0602 -0.1043 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C12 mock treatment 720.0 119.0 0.55 600.0 -28.9 -0.12 0.3034 0.5412 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C13 compound treatment 480.0 -121.0 -0.56 800.0 171.0 0.7 0.1023 0.1136 3189545 PK04_103055 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C14 compound treatment 2560.0 1960.0 9.04 2520.0 1890.0 7.79 11.9026 0.9972 3189546 PK04_103056 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C15 mock treatment 480.0 -121.0 -0.56 600.0 -28.9 -0.12 -0.4802 -0.8384 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C16 mock treatment 680.0 78.7 0.36 520.0 -109.0 -0.45 -0.0602 -0.1043 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C17 compound treatment 480.0 -121.0 -0.56 800.0 171.0 0.7 0.1023 0.1136 3070427 PK04_103057 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C18 compound treatment 1520.0 919.0 4.24 2000.0 1370.0 5.65 6.9927 0.99 3189660 PK04_103058 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C19 compound treatment 1600.0 999.0 4.61 1240.0 611.0 2.52 5.0404 0.9595 3070428 PK04_103059 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C20 compound treatment 2560.0 1960.0 9.04 2360.0 1730.0 7.13 11.4367 0.9931 3189661 PK04_103060 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C21 compound treatment 1160.0 559.0 2.58 1120.0 491.0 2.02 3.2544 0.9928 3189662 PK04_103061 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C22 compound treatment 1880.0 1280.0 5.9 2160.0 1530.0 6.31 8.6341 0.9995 3070429 PK04_103062 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C23 compound treatment 600.0 -1.33 -0.01 920.0 291.0 1.2 0.8436 0.7035 3189663 PK04_103063 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 C24 compound treatment 2040.0 1440.0 6.64 1960.0 1330.0 5.48 8.5739 0.9955 3189664 PK04_103064 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D01 compound treatment 1680.0 1080.0 4.98 1640.0 1010.0 4.16 6.4666 0.996 3070430 PK04_103065 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D02 compound treatment 440.0 -161.0 -0.74 600.0 -28.9 -0.12 -0.6108 -0.8097 3189665 PK04_103066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D03 compound treatment 1920.0 1320.0 6.09 1880.0 1250.0 5.15 7.9492 0.9966 3070431 PK04_103067 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D04 compound treatment 880.0 279.0 1.29 1280.0 651.0 2.68 2.8063 0.9434 3189666 PK04_103068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D05 compound treatment 720.0 119.0 0.55 1600.0 971.0 4.0 3.2159 0.7965 3189667 PK04_103069 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D06 compound treatment 840.0 239.0 1.1 640.0 11.1 0.05 0.8117 0.7359 3189668 PK04_103070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D07 compound treatment 680.0 78.7 0.36 1120.0 491.0 2.02 1.6873 0.8209 3070432 PK04_103071 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D08 compound treatment 1120.0 519.0 2.39 480.0 -149.0 -0.61 1.2598 0.5096 3189669 PK04_103072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D09 compound treatment 2800.0 2200.0 10.15 2480.0 1850.0 7.62 12.5697 0.99 3070433 PK04_103073 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D10 compound treatment 600.0 -1.33 -0.01 560.0 -68.9 -0.28 -0.2049 -0.7223 3189670 PK04_103074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D11 mock treatment 680.0 78.7 0.36 760.0 131.0 0.54 0.6388 0.9814 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D12 mock treatment 680.0 78.7 0.36 760.0 131.0 0.54 0.6388 0.9814 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D13 compound treatment 2000.0 1400.0 6.46 2600.0 1970.0 8.12 10.3073 0.9936 3189671 PK04_103075 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D14 compound treatment 680.0 78.7 0.36 520.0 -109.0 -0.45 -0.0602 -0.1043 3070434 PK04_103076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D15 mock treatment 600.0 -1.33 -0.01 680.0 51.1 0.21 0.1446 0.6862 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D16 mock treatment 680.0 78.7 0.36 520.0 -109.0 -0.45 -0.0602 -0.1043 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D17 compound treatment 3480.0 2880.0 13.29 2760.0 2130.0 8.78 15.6053 0.9797 3189672 PK04_103077 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D18 compound treatment 720.0 119.0 0.55 520.0 -109.0 -0.45 0.0704 0.0994 3189673 PK04_103078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D19 compound treatment 3640.0 3040.0 14.03 3480.0 2850.0 11.74 18.2247 0.9961 3070435 PK04_103079 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D20 compound treatment 920.0 319.0 1.47 800.0 171.0 0.7 1.5389 0.9432 3189674 PK04_103080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D21 compound treatment 1000.0 399.0 1.84 1000.0 371.0 1.53 2.3825 0.9957 3189675 PK04_103081 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D22 compound treatment 1480.0 879.0 4.06 1160.0 531.0 2.19 4.4157 0.958 3070436 PK04_103082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D23 compound treatment 840.0 239.0 1.1 1120.0 491.0 2.02 2.2097 0.9592 3189676 PK04_103083 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 D24 compound treatment 480.0 -121.0 -0.56 720.0 91.1 0.38 -0.1307 -0.1938 3070437 PK04_103084 CN1CCC(=CC1C2CC2)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E01 mock treatment 480.0 -121.0 -0.56 440.0 -189.0 -0.78 -0.9462 -0.987 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E02 mock treatment 440.0 -161.0 -0.74 480.0 -149.0 -0.61 -0.9603 -0.9953 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E03 compound treatment 680.0 78.7 0.36 480.0 -149.0 -0.61 -0.1767 -0.248 3189677 PK04_103085 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E04 compound treatment 600.0 -1.33 -0.01 400.0 -229.0 -0.94 -0.6709 -0.7117 3070438 PK04_103086 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E05 compound treatment 680.0 78.7 0.36 680.0 51.1 0.21 0.4058 0.9664 3189678 PK04_103087 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E06 compound treatment 680.0 78.7 0.36 560.0 -68.9 -0.28 0.0563 0.1222 3189679 PK04_103088 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E07 compound treatment 760.0 159.0 0.73 600.0 -28.9 -0.12 0.434 0.5848 3189680 PK04_103089 COCC(=C)C(=O)CC[C@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E08 compound treatment 560.0 -41.3 -0.19 720.0 91.1 0.38 0.1305 0.3099 3070490 PK04_103090 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E09 mock treatment 720.0 119.0 0.55 840.0 211.0 0.87 1.0024 0.9752 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E10 mock treatment 600.0 -1.33 -0.01 760.0 131.0 0.54 0.3776 0.699 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E11 compound treatment 2640.0 2040.0 9.41 2920.0 2290.0 9.44 13.3288 1.0 3187704 PK04_103091 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E12 compound treatment 1440.0 839.0 3.87 1400.0 771.0 3.18 4.9841 0.9952 3070491 PK04_103092 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E13 compound treatment 2640.0 2040.0 9.41 4480.0 3850.0 15.86 17.8723 0.969 3187705 PK04_103093 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E14 compound treatment 1160.0 559.0 2.58 1400.0 771.0 3.18 4.0699 0.9947 3187706 PK04_103094 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccccc1OCCO)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E15 compound treatment 920.0 319.0 1.47 800.0 171.0 0.7 1.5389 0.9432 3070492 PK04_103095 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E16 compound treatment 1160.0 559.0 2.58 1280.0 651.0 2.68 3.7204 0.9998 3187707 PK04_103096 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E17 mock treatment 800.0 199.0 0.92 640.0 11.1 0.05 0.6811 0.7416 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E18 mock treatment 960.0 359.0 1.66 600.0 -28.9 -0.12 1.087 0.6547 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E19 compound treatment 2080.0 1480.0 6.83 2760.0 2130.0 8.78 11.0345 0.9923 3070493 PK04_103097 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E20 compound treatment 1600.0 999.0 4.61 1560.0 931.0 3.84 5.9724 0.9958 3187708 PK04_103098 CC(C)C(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E21 compound treatment 2560.0 1960.0 9.04 4520.0 3890.0 16.03 17.7276 0.9633 3187709 PK04_103099 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E22 compound treatment 1240.0 639.0 2.95 2440.0 1810.0 7.46 7.3601 0.9175 3070494 PK04_103100 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E23 compound treatment 1480.0 879.0 4.06 2000.0 1370.0 5.65 6.8621 0.9868 3187710 PK04_103101 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 E24 compound treatment 1720.0 1120.0 5.17 1880.0 1250.0 5.15 7.2962 1.0 3187711 PK04_103102 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F01 mock treatment 600.0 -1.33 -0.01 520.0 -109.0 -0.45 -0.3214 -0.7167 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F02 mock treatment 440.0 -161.0 -0.74 480.0 -149.0 -0.61 -0.9603 -0.9953 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F03 compound treatment 440.0 -161.0 -0.74 600.0 -28.9 -0.12 -0.6108 -0.8097 3070495 PK04_103103 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F04 compound treatment 520.0 -81.3 -0.38 400.0 -229.0 -0.94 -0.9321 -0.9186 3187712 PK04_103104 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F05 compound treatment 720.0 119.0 0.55 720.0 91.1 0.38 0.6529 0.983 3070496 PK04_103105 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F06 compound treatment 520.0 -81.3 -0.38 600.0 -28.9 -0.12 -0.3496 -0.8875 3187713 PK04_103106 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F07 compound treatment 1000.0 399.0 1.84 760.0 131.0 0.54 1.6835 0.8776 3070497 PK04_103107 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F08 compound treatment 720.0 119.0 0.55 560.0 -68.9 -0.28 0.1869 0.3029 3187714 PK04_103108 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F09 mock treatment 720.0 119.0 0.55 520.0 -109.0 -0.45 0.0704 0.0994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F10 mock treatment 400.0 -201.0 -0.93 520.0 -109.0 -0.45 -0.9744 -0.9441 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F11 compound treatment 640.0 38.7 0.18 800.0 171.0 0.7 0.6247 0.8591 3187715 PK04_103109 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(OCCO)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F12 compound treatment 920.0 319.0 1.47 560.0 -68.9 -0.28 0.8399 0.5605 3070498 PK04_103110 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F13 compound treatment 2000.0 1400.0 6.46 2160.0 1530.0 6.31 9.0258 0.9999 3187716 PK04_103111 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F14 compound treatment 1200.0 599.0 2.76 920.0 291.0 1.2 2.8025 0.9301 3070499 PK04_103112 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F15 compound treatment 1080.0 479.0 2.21 880.0 251.0 1.03 2.2942 0.9402 3187717 PK04_103113 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F16 compound treatment 400.0 -201.0 -0.93 480.0 -149.0 -0.61 -1.0909 -0.9796 3187718 PK04_103114 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F17 mock treatment 640.0 38.7 0.18 760.0 131.0 0.54 0.5082 0.8933 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F18 mock treatment 640.0 38.7 0.18 880.0 251.0 1.03 0.8577 0.8171 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F19 compound treatment 960.0 359.0 1.66 1360.0 731.0 3.01 3.3004 0.9603 3070500 PK04_103115 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1cccc(OCCO)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F20 compound treatment 600.0 -1.33 -0.01 960.0 331.0 1.36 0.9601 0.7039 3187719 PK04_103116 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F21 compound treatment 1920.0 1320.0 6.09 2360.0 1730.0 7.13 9.3472 0.9969 3070501 PK04_103117 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F22 compound treatment 1600.0 999.0 4.61 1960.0 1330.0 5.48 7.1374 0.9963 3187720 PK04_103118 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F23 compound treatment 1280.0 679.0 3.13 1200.0 571.0 2.35 3.8792 0.99 3187721 PK04_103119 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 F24 compound treatment 840.0 239.0 1.1 1080.0 451.0 1.86 2.0932 0.9689 3070502 PK04_103120 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G01 compound treatment 840.0 239.0 1.1 1120.0 491.0 2.02 2.2097 0.9592 3187722 PK04_103121 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G02 compound treatment 800.0 199.0 0.92 1520.0 891.0 3.67 3.2441 0.8574 3187723 PK04_103122 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G03 mock treatment 560.0 -41.3 -0.19 520.0 -109.0 -0.45 -0.452 -0.9276 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G04 mock treatment 760.0 159.0 0.73 480.0 -149.0 -0.61 0.0845 0.0884 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G05 compound treatment 880.0 279.0 1.29 1080.0 451.0 1.86 2.2238 0.9839 3070503 PK04_103123 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G06 compound treatment 720.0 119.0 0.55 1360.0 731.0 3.01 2.5169 0.8223 3187724 PK04_103124 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G07 compound treatment 2040.0 1440.0 6.64 880.0 251.0 1.03 5.4285 0.8075 3070504 PK04_103125 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G08 compound treatment 520.0 -81.3 -0.38 520.0 -109.0 -0.45 -0.5826 -0.9961 3187725 PK04_103126 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G09 compound treatment 520.0 -81.3 -0.38 680.0 51.1 0.21 -0.1166 -0.2707 3187726 PK04_103127 CCCCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G10 compound treatment 720.0 119.0 0.55 760.0 131.0 0.54 0.7694 1.0 3070543 PK04_103128 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G11 compound treatment 560.0 -41.3 -0.19 840.0 211.0 0.87 0.48 0.5391 3187727 PK04_103129 CC(C)C(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G12 compound treatment 4080.0 3480.0 16.06 7120.0 6490.0 26.74 30.2626 0.9703 3187844 PK04_103130 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G13 compound treatment 680.0 78.7 0.36 720.0 91.1 0.38 0.5223 0.9999 3070544 PK04_103131 COCC(=C)C(=O)CC[C@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G14 compound treatment 960.0 359.0 1.66 1120.0 491.0 2.02 2.6014 0.9951 3187845 PK04_103132 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G15 compound treatment 880.0 279.0 1.29 1200.0 571.0 2.35 2.5733 0.9597 3070545 PK04_103133 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G16 compound treatment 1760.0 1160.0 5.35 1640.0 1010.0 4.16 6.7278 0.9923 3187846 PK04_103134 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G17 compound treatment 1160.0 559.0 2.58 1200.0 571.0 2.35 3.4874 0.9989 3070546 PK04_103135 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G18 compound treatment 1880.0 1280.0 5.9 1400.0 771.0 3.18 6.4206 0.9577 3187847 PK04_103136 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G19 mock treatment 560.0 -41.3 -0.19 760.0 131.0 0.54 0.247 0.4312 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G20 mock treatment 480.0 -121.0 -0.56 720.0 91.1 0.38 -0.1307 -0.1938 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G21 compound treatment 840.0 239.0 1.1 1200.0 571.0 2.35 2.4427 0.9403 3070547 PK04_103137 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G22 compound treatment 2440.0 1840.0 8.49 2320.0 1690.0 6.97 10.9284 0.9952 3187848 PK04_103138 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G23 compound treatment 1080.0 479.0 2.21 1760.0 1130.0 4.66 4.8572 0.9419 3070548 PK04_103139 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 G24 compound treatment 600.0 -1.33 -0.01 920.0 291.0 1.2 0.8436 0.7035 3187849 PK04_103140 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(CO)o1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H01 compound treatment 920.0 319.0 1.47 800.0 171.0 0.7 1.5389 0.9432 3070549 PK04_103141 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccccc1OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H02 compound treatment 440.0 -161.0 -0.74 840.0 211.0 0.87 0.0882 0.0771 3187850 PK04_103142 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H03 mock treatment 640.0 38.7 0.18 440.0 -189.0 -0.78 -0.4238 -0.531 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H04 mock treatment 440.0 -161.0 -0.74 440.0 -189.0 -0.78 -1.0768 -0.9998 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H05 compound treatment 520.0 -81.3 -0.38 600.0 -28.9 -0.12 -0.3496 -0.8875 3187851 PK04_103143 CCCCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H06 compound treatment 480.0 -121.0 -0.56 480.0 -149.0 -0.61 -0.8297 -0.999 3187852 PK04_103144 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H07 compound treatment 640.0 38.7 0.18 680.0 51.1 0.21 0.2752 0.9966 3070550 PK04_103145 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H08 compound treatment 520.0 -81.3 -0.38 640.0 11.1 0.05 -0.2331 -0.6161 3187853 PK04_103146 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H09 compound treatment 560.0 -41.3 -0.19 800.0 171.0 0.7 0.3635 0.4978 3070551 PK04_103147 COCC(=C)C(=O)CC[C@@H](OC(=O)C)c1ccc(CO)o1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H10 compound treatment 520.0 -81.3 -0.38 640.0 11.1 0.05 -0.2331 -0.6161 3070552 PK04_103148 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H11 compound treatment 560.0 -41.3 -0.19 560.0 -68.9 -0.28 -0.3355 -0.9814 3187854 PK04_103149 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H12 compound treatment 440.0 -161.0 -0.74 760.0 131.0 0.54 -0.1448 -0.1573 3070553 PK04_103150 CN1CCC(=CC1c2cccs2)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H13 compound treatment 1280.0 679.0 3.13 1200.0 571.0 2.35 3.8792 0.99 3187855 PK04_103151 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H14 compound treatment 880.0 279.0 1.29 520.0 -109.0 -0.45 0.5928 0.4351 3187856 PK04_103152 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H15 compound treatment 600.0 -1.33 -0.01 880.0 251.0 1.03 0.7271 0.7029 3070554 PK04_103153 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(OCCO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H16 compound treatment 600.0 -1.33 -0.01 800.0 171.0 0.7 0.4941 0.7009 3187857 PK04_103154 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H17 compound treatment 1000.0 399.0 1.84 1320.0 691.0 2.85 3.3145 0.9777 3187858 PK04_103155 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H18 compound treatment 1360.0 759.0 3.5 1040.0 411.0 1.69 3.6744 0.9444 3070555 PK04_103156 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H19 mock treatment 480.0 -121.0 -0.56 680.0 51.1 0.21 -0.2472 -0.413 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H20 mock treatment 480.0 -121.0 -0.56 560.0 -68.9 -0.28 -0.5967 -0.9502 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H21 compound treatment 1040.0 439.0 2.03 880.0 251.0 1.03 2.1636 0.9514 3187859 PK04_103157 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H22 compound treatment 600.0 -1.33 -0.01 720.0 91.1 0.38 0.2611 0.6954 3070556 PK04_103158 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H23 compound treatment 960.0 359.0 1.66 1040.0 411.0 1.69 2.3684 0.9999 3187860 PK04_103159 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3cccc(OCCO)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 H24 compound treatment 1440.0 839.0 3.87 2200.0 1570.0 6.47 7.314 0.9699 3070597 PK04_103160 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I01 compound treatment 1400.0 799.0 3.69 2000.0 1370.0 5.65 6.6009 0.9787 3187861 PK04_103161 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I02 compound treatment 760.0 159.0 0.73 840.0 211.0 0.87 1.133 0.9964 3187862 PK04_103162 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I03 compound treatment 600.0 -1.33 -0.01 640.0 11.1 0.05 0.0281 0.6069 3070598 PK04_103163 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I04 compound treatment 560.0 -41.3 -0.19 640.0 11.1 0.05 -0.1025 -0.5221 3187863 PK04_103164 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I05 mock treatment 1040.0 439.0 2.03 720.0 91.1 0.38 1.6976 0.8241 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I06 mock treatment 640.0 38.7 0.18 440.0 -189.0 -0.78 -0.4238 -0.531 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I07 compound treatment 1440.0 839.0 3.87 1160.0 531.0 2.19 4.2851 0.9635 3070599 PK04_103165 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I08 compound treatment 680.0 78.7 0.36 520.0 -109.0 -0.45 -0.0602 -0.1043 3187864 PK04_103166 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I09 compound treatment 640.0 38.7 0.18 1320.0 691.0 2.85 2.1392 0.75 3187865 PK04_103167 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I10 compound treatment 600.0 -1.33 -0.01 680.0 51.1 0.21 0.1446 0.6862 3070600 PK04_103168 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I11 compound treatment 960.0 359.0 1.66 1080.0 451.0 1.86 2.4849 0.9983 3187866 PK04_103169 COCC(=C=CC[C@H](O)c1ccccc1OCCO)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I12 compound treatment 2840.0 2240.0 10.34 3120.0 2490.0 10.26 14.5643 1.0 3187978 PK04_103170 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I13 compound treatment 600.0 -1.33 -0.01 960.0 331.0 1.36 0.9601 0.7039 3070601 PK04_103171 CCCCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I14 compound treatment 3800.0 3200.0 14.77 2400.0 1770.0 7.3 15.6016 0.9471 3187979 PK04_103172 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I15 compound treatment 880.0 279.0 1.29 960.0 331.0 1.36 1.8743 0.9996 3070602 PK04_103173 CC(C)C(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I16 compound treatment 1160.0 559.0 2.58 1120.0 491.0 2.02 3.2544 0.9928 3187980 PK04_103174 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I17 compound treatment 840.0 239.0 1.1 880.0 251.0 1.03 1.5107 0.9995 3070603 PK04_103175 COCC(=C=CC[C@H](O)c1ccc(CO)o1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I18 compound treatment 720.0 119.0 0.55 600.0 -28.9 -0.12 0.3034 0.5412 3187981 PK04_103176 COCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I19 compound treatment 2360.0 1760.0 8.12 2200.0 1570.0 6.47 10.3177 0.9937 3070604 PK04_103177 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I20 compound treatment 720.0 119.0 0.55 1040.0 411.0 1.69 1.5849 0.8904 3187982 PK04_103178 CC(C)C(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I21 mock treatment 720.0 119.0 0.55 720.0 91.1 0.38 0.6529 0.983 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I22 mock treatment 680.0 78.7 0.36 840.0 211.0 0.87 0.8718 0.925 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I23 compound treatment 2360.0 1760.0 8.12 2800.0 2170.0 8.94 12.0652 0.9988 3187983 PK04_103179 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 I24 compound treatment 960.0 359.0 1.66 1520.0 891.0 3.67 3.7664 0.9353 3070605 PK04_103180 CCCCC(=C)/C(=C/C[C@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cnc4ccccc4c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J01 compound treatment 1000.0 399.0 1.84 2480.0 1850.0 7.62 6.693 0.8533 3187984 PK04_103181 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J02 compound treatment 400.0 -201.0 -0.93 1000.0 371.0 1.53 0.4236 0.2368 3187985 PK04_103182 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J03 compound treatment 600.0 -1.33 -0.01 1880.0 1250.0 5.15 3.6396 0.7063 3070606 PK04_103183 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J04 compound treatment 400.0 -201.0 -0.93 520.0 -109.0 -0.45 -0.9744 -0.9441 3187986 PK04_103184 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J05 mock treatment 480.0 -121.0 -0.56 720.0 91.1 0.38 -0.1307 -0.1938 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J06 mock treatment 640.0 38.7 0.18 1240.0 611.0 2.52 1.9062 0.7554 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J07 compound treatment 1320.0 719.0 3.32 760.0 131.0 0.54 2.7283 0.8115 3187987 PK04_103185 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccccc3OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J08 compound treatment 600.0 -1.33 -0.01 600.0 -28.9 -0.12 -0.0884 -0.7427 3070607 PK04_103186 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J09 compound treatment 560.0 -41.3 -0.19 600.0 -28.9 -0.12 -0.219 -0.974 3187988 PK04_103187 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J10 compound treatment 680.0 78.7 0.36 560.0 -68.9 -0.28 0.0563 0.1222 3070608 PK04_103188 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J11 compound treatment 720.0 119.0 0.55 1000.0 371.0 1.53 1.4684 0.9042 3187989 PK04_103189 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J12 compound treatment 1320.0 719.0 3.32 1120.0 491.0 2.02 3.7768 0.9718 3070609 PK04_103190 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J13 compound treatment 2240.0 1640.0 7.57 1640.0 1010.0 4.16 8.2949 0.9604 3187990 PK04_103191 COCC(=C)C(=O)CC[C@@H](OC(=O)c1ccccc1c2ccccc2C(=O)O)c3ccc(CO)o3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J14 compound treatment 1680.0 1080.0 4.98 920.0 291.0 1.2 4.3696 0.853 3187991 PK04_103192 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J15 compound treatment 2160.0 1560.0 7.2 2840.0 2210.0 9.11 11.5287 0.9932 3070610 PK04_103193 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J16 compound treatment 680.0 78.7 0.36 720.0 91.1 0.38 0.5223 0.9999 3187992 PK04_103194 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J17 compound treatment 3160.0 2560.0 11.81 4640.0 4010.0 16.52 20.036 0.9865 3070654 PK04_103195 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J18 compound treatment 680.0 78.7 0.36 720.0 91.1 0.38 0.5223 0.9999 3187993 PK04_103196 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J19 compound treatment 1400.0 799.0 3.69 1680.0 1050.0 4.33 5.669 0.9968 3070655 PK04_103197 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(OCCO)cc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J20 compound treatment 1080.0 479.0 2.21 1760.0 1130.0 4.66 4.8572 0.9419 3187994 PK04_103198 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J21 mock treatment 800.0 199.0 0.92 760.0 131.0 0.54 1.0306 0.9681 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J22 mock treatment 520.0 -81.3 -0.38 640.0 11.1 0.05 -0.2331 -0.6161 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J23 compound treatment 3040.0 2440.0 11.26 3960.0 3330.0 13.72 17.6637 0.9952 3187995 PK04_103199 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 J24 compound treatment 1200.0 599.0 2.76 2000.0 1370.0 5.65 5.948 0.946 3070656 PK04_103200 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K01 compound treatment 600.0 -1.33 -0.01 840.0 211.0 0.87 0.6106 0.7021 3187996 PK04_103201 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K02 compound treatment 1160.0 559.0 2.58 1200.0 571.0 2.35 3.4874 0.9989 3187997 PK04_103202 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K03 compound treatment 640.0 38.7 0.18 1800.0 1170.0 4.82 3.5372 0.7328 3070657 PK04_103203 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K04 compound treatment 1400.0 799.0 3.69 1280.0 651.0 2.68 4.504 0.9878 3187998 PK04_103204 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K05 compound treatment 720.0 119.0 0.55 1120.0 491.0 2.02 1.8179 0.8674 3070658 PK04_103205 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K06 compound treatment 720.0 119.0 0.55 1120.0 491.0 2.02 1.8179 0.8674 3187999 PK04_103206 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K07 mock treatment 1160.0 559.0 2.58 520.0 -109.0 -0.45 1.5069 0.5756 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K08 mock treatment 520.0 -81.3 -0.38 720.0 91.1 0.38 -1.0E-4 -1.0E-4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K09 compound treatment 1240.0 639.0 2.95 1640.0 1010.0 4.16 5.0301 0.9857 3188000 PK04_103207 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K10 compound treatment 1200.0 599.0 2.76 1280.0 651.0 2.68 3.851 0.9999 3070659 PK04_103208 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K11 compound treatment 880.0 279.0 1.29 1440.0 811.0 3.34 3.2722 0.914 3188108 PK04_103209 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K12 compound treatment 1760.0 1160.0 5.35 1200.0 571.0 2.35 5.4463 0.9319 3188109 PK04_103210 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K13 compound treatment 4160.0 3560.0 16.43 2120.0 1490.0 6.14 15.9614 0.9099 3070660 PK04_103211 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K14 compound treatment 880.0 279.0 1.29 1000.0 371.0 1.53 1.9908 0.9963 3188110 PK04_103212 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K15 mock treatment 800.0 199.0 0.92 760.0 131.0 0.54 1.0306 0.9681 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K16 mock treatment 520.0 -81.3 -0.38 680.0 51.1 0.21 -0.1166 -0.2707 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K17 compound treatment 1440.0 839.0 3.87 1440.0 811.0 3.34 5.1006 0.9973 3070661 PK04_103213 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K18 compound treatment 600.0 -1.33 -0.01 1040.0 411.0 1.69 1.1931 0.7045 3188111 PK04_103214 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K19 compound treatment 1960.0 1360.0 6.27 1800.0 1170.0 4.82 7.8468 0.9916 3188112 PK04_103215 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K20 compound treatment 640.0 38.7 0.18 1520.0 891.0 3.67 2.7217 0.7406 3070662 PK04_103216 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K21 compound treatment 2040.0 1440.0 6.64 1680.0 1050.0 4.33 7.7585 0.9785 3188113 PK04_103217 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K22 compound treatment 600.0 -1.33 -0.01 760.0 131.0 0.54 0.3776 0.699 3188114 PK04_103218 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K23 mock treatment 680.0 78.7 0.36 800.0 171.0 0.7 0.7553 0.9524 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 K24 mock treatment 440.0 -161.0 -0.74 720.0 91.1 0.38 -0.2613 -0.3132 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L01 compound treatment 640.0 38.7 0.18 1160.0 531.0 2.19 1.6732 0.7623 3070663 PK04_103219 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L02 compound treatment 520.0 -81.3 -0.38 520.0 -109.0 -0.45 -0.5826 -0.9961 3188115 PK04_103220 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L03 compound treatment 840.0 239.0 1.1 3160.0 2530.0 10.43 8.1511 0.7775 3070664 PK04_103221 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2cccc(OCCO)c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L04 compound treatment 480.0 -121.0 -0.56 640.0 11.1 0.05 -0.3637 -0.647 3188116 PK04_103222 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L05 compound treatment 1080.0 479.0 2.21 1520.0 891.0 3.67 4.1582 0.9705 3070665 PK04_103223 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L06 compound treatment 880.0 279.0 1.29 1200.0 571.0 2.35 2.5733 0.9597 3188117 PK04_103224 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L07 mock treatment 560.0 -41.3 -0.19 600.0 -28.9 -0.12 -0.219 -0.974 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L08 mock treatment 520.0 -81.3 -0.38 600.0 -28.9 -0.12 -0.3496 -0.8875 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L09 compound treatment 1120.0 519.0 2.39 2840.0 2210.0 9.11 8.1333 0.8637 3188118 PK04_103225 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L10 compound treatment 800.0 199.0 0.92 1120.0 491.0 2.02 2.0791 0.936 3188119 PK04_103226 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L11 compound treatment 4880.0 4280.0 19.76 2600.0 1970.0 8.12 19.7101 0.9228 3070666 PK04_103227 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccccc2OCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L12 compound treatment 1840.0 1240.0 5.72 640.0 11.1 0.05 4.0765 0.7128 3188120 PK04_103228 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L13 compound treatment 1080.0 479.0 2.21 920.0 291.0 1.2 2.4107 0.9587 3188121 PK04_103229 CCCCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L14 compound treatment 840.0 239.0 1.1 600.0 -28.9 -0.12 0.6952 0.6272 3188122 PK04_103230 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L15 mock treatment 720.0 119.0 0.55 800.0 171.0 0.7 0.8859 0.9922 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L16 mock treatment 720.0 119.0 0.55 440.0 -189.0 -0.78 -0.1626 -0.1709 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L17 compound treatment 560.0 -41.3 -0.19 840.0 211.0 0.87 0.48 0.5391 3070709 PK04_103231 CC(C)C(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L18 compound treatment 880.0 279.0 1.29 1120.0 491.0 2.02 2.3403 0.9761 3188123 PK04_103232 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L19 compound treatment 600.0 -1.33 -0.01 840.0 211.0 0.87 0.6106 0.7021 3070710 PK04_103233 COCC(=C)C(=O)CC[C@@H](OC(=O)c1cccnc1)c2ccc(CO)o2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L20 compound treatment 1000.0 399.0 1.84 800.0 171.0 0.7 1.8 0.9132 3188124 PK04_103234 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L21 compound treatment 1640.0 1040.0 4.8 2120.0 1490.0 6.14 7.734 0.9925 3070711 PK04_103235 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L22 compound treatment 1120.0 519.0 2.39 1440.0 811.0 3.34 4.0558 0.9867 3188125 PK04_103236 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L23 mock treatment 600.0 -1.33 -0.01 840.0 211.0 0.87 0.6106 0.7021 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 L24 mock treatment 560.0 -41.3 -0.19 600.0 -28.9 -0.12 -0.219 -0.974 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M01 compound treatment 2560.0 1960.0 9.04 2240.0 1610.0 6.64 11.0872 0.9884 3070712 PK04_103237 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M02 compound treatment 760.0 159.0 0.73 1160.0 531.0 2.19 2.065 0.895 3188126 PK04_103238 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(OCCO)cc3)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M03 compound treatment 600.0 -1.33 -0.01 1200.0 571.0 2.35 1.6591 0.7053 3070713 PK04_103239 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M04 compound treatment 480.0 -121.0 -0.56 1560.0 931.0 3.84 2.3158 0.5975 3188127 PK04_103240 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M05 compound treatment 1680.0 1080.0 4.98 1320.0 691.0 2.85 5.5346 0.9648 3188128 PK04_103241 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M06 compound treatment 680.0 78.7 0.36 520.0 -109.0 -0.45 -0.0602 -0.1043 3070714 PK04_103242 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M07 compound treatment 1560.0 959.0 4.43 3000.0 2370.0 9.77 10.0358 0.9359 3188237 PK04_103243 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M08 compound treatment 560.0 -41.3 -0.19 760.0 131.0 0.54 0.247 0.4312 3070715 PK04_103244 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccc(CO)o2)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M09 mock treatment 1040.0 439.0 2.03 480.0 -149.0 -0.61 0.9986 0.4719 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M10 mock treatment 640.0 38.7 0.18 520.0 -109.0 -0.45 -0.1908 -0.3953 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M11 compound treatment 1800.0 1200.0 5.53 2000.0 1370.0 5.65 7.9069 0.9999 3188238 PK04_103245 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M12 compound treatment 3920.0 3320.0 15.32 1960.0 1330.0 5.48 14.7119 0.904 3188239 PK04_103246 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M13 mock treatment 880.0 279.0 1.29 480.0 -149.0 -0.61 0.4763 0.3342 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M14 mock treatment 480.0 -121.0 -0.56 600.0 -28.9 -0.12 -0.4802 -0.8384 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M15 compound treatment 2560.0 1960.0 9.04 3440.0 2810.0 11.58 14.5821 0.9925 3070716 PK04_103247 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M16 compound treatment 1040.0 439.0 2.03 1400.0 771.0 3.18 3.6781 0.9764 3188240 PK04_103248 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(CO)o1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M17 compound treatment 4600.0 4000.0 18.46 4520.0 3890.0 16.03 24.3879 0.9975 3070717 PK04_103249 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M18 compound treatment 2880.0 2280.0 10.52 2000.0 1370.0 5.65 11.4329 0.9575 3188241 PK04_103250 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M19 compound treatment 1520.0 919.0 4.24 1360.0 731.0 3.01 5.1287 0.9859 3188242 PK04_103251 CCCCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M20 compound treatment 3240.0 2640.0 12.18 3240.0 2610.0 10.75 16.2197 0.9981 3070718 PK04_103252 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)C)c2ccccc2OCCO)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M21 compound treatment 1200.0 599.0 2.76 1840.0 1210.0 4.99 5.482 0.9612 3188243 PK04_103253 CC(C)C(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M22 compound treatment 2720.0 2120.0 9.78 3760.0 3130.0 12.9 16.0365 0.9907 3188244 PK04_103254 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccccc1OCCO)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M23 compound treatment 960.0 359.0 1.66 1320.0 691.0 2.85 3.1839 0.9668 3188245 PK04_103255 COCC(=C=CC[C@H](O)c1ccc(OCCO)cc1)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 M24 compound treatment 1600.0 999.0 4.61 1120.0 491.0 2.02 4.6909 0.9316 3070768 PK04_103256 COCC(=C)/C(=C/C[C@@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N01 compound treatment 440.0 -161.0 -0.74 520.0 -109.0 -0.45 -0.8438 -0.9705 3188246 PK04_103257 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N02 compound treatment 440.0 -161.0 -0.74 520.0 -109.0 -0.45 -0.8438 -0.9705 3188247 PK04_103258 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N03 compound treatment 800.0 199.0 0.92 440.0 -189.0 -0.78 0.0986 0.082 3070772 PK04_103259 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N04 compound treatment 400.0 -201.0 -0.93 840.0 211.0 0.87 -0.0424 -0.0333 3188248 PK04_103260 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N05 compound treatment 1200.0 599.0 2.76 1160.0 531.0 2.19 3.5015 0.9933 3188249 PK04_103261 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N06 compound treatment 1800.0 1200.0 5.53 1280.0 651.0 2.68 5.8099 0.9447 3188250 PK04_103262 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N07 compound treatment 760.0 159.0 0.73 920.0 291.0 1.2 1.366 0.972 3070060 PK04_103263 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N08 compound treatment 1560.0 959.0 4.43 1120.0 491.0 2.02 4.5603 0.937 3188251 PK04_103264 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N09 mock treatment 480.0 -121.0 -0.56 480.0 -149.0 -0.61 -0.8297 -0.999 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N10 mock treatment 560.0 -41.3 -0.19 400.0 -229.0 -0.94 -0.8015 -0.8334 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N11 compound treatment 600.0 -1.33 -0.01 560.0 -68.9 -0.28 -0.2049 -0.7223 3070061 PK04_103265 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N12 compound treatment 600.0 -1.33 -0.01 560.0 -68.9 -0.28 -0.2049 -0.7223 3188252 PK04_103266 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N13 mock treatment 400.0 -201.0 -0.93 520.0 -109.0 -0.45 -0.9744 -0.9441 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N14 mock treatment 640.0 38.7 0.18 800.0 171.0 0.7 0.6247 0.8591 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N15 compound treatment 2480.0 1880.0 8.67 4640.0 4010.0 16.52 17.8159 0.9548 3070062 PK04_103267 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N16 compound treatment 840.0 239.0 1.1 720.0 91.1 0.38 1.0447 0.8974 3188253 PK04_103268 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N17 compound treatment 1160.0 559.0 2.58 1760.0 1130.0 4.66 5.1184 0.9611 3070063 PK04_103269 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N18 compound treatment 1640.0 1040.0 4.8 1200.0 571.0 2.35 5.0545 0.9463 3188254 PK04_103270 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N19 compound treatment 800.0 199.0 0.92 720.0 91.1 0.38 0.9141 0.9223 3070064 PK04_103271 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N20 compound treatment 600.0 -1.33 -0.01 760.0 131.0 0.54 0.3776 0.699 3188255 PK04_103272 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N21 compound treatment 880.0 279.0 1.29 1240.0 611.0 2.52 2.6898 0.9515 3070065 PK04_103273 CCCCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N22 compound treatment 400.0 -201.0 -0.93 440.0 -189.0 -0.78 -1.2073 -0.9961 3188256 PK04_103274 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N23 compound treatment 800.0 199.0 0.92 640.0 11.1 0.05 0.6811 0.7416 3070066 PK04_103275 CC(C)C(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 N24 compound treatment 440.0 -161.0 -0.74 480.0 -149.0 -0.61 -0.9603 -0.9953 3188257 PK04_103276 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O01 compound treatment 480.0 -121.0 -0.56 1000.0 371.0 1.53 0.6848 0.4206 3188258 PK04_103277 CCCCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O02 compound treatment 800.0 199.0 0.92 640.0 11.1 0.05 0.6811 0.7416 3070067 PK04_103278 CC(C)C(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O03 compound treatment 960.0 359.0 1.66 1000.0 371.0 1.53 2.2519 0.9992 3188259 PK04_103279 CC(C)C(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O04 compound treatment 640.0 38.7 0.18 1000.0 371.0 1.53 1.2072 0.7844 3188369 PK04_103280 CCCCC(=C)/C(=C/C[C@@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cnc3ccccc3c2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O05 compound treatment 680.0 78.7 0.36 1000.0 371.0 1.53 1.3378 0.8514 3070068 PK04_103281 COCC(=C=CC[C@H](O)c1cccc(OCCO)c1)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O06 compound treatment 440.0 -161.0 -0.74 1120.0 491.0 2.02 0.9037 0.4192 3188370 PK04_103282 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O07 compound treatment 1320.0 719.0 3.32 2000.0 1370.0 5.65 6.3398 0.9679 3070069 PK04_103283 CCCCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O08 compound treatment 1560.0 959.0 4.43 2600.0 1970.0 8.12 8.8708 0.9593 3188371 PK04_103284 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccc(CO)o3)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O09 compound treatment 800.0 199.0 0.92 2120.0 1490.0 6.14 4.9915 0.8038 3188372 PK04_103285 CC(C)C(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O10 compound treatment 1200.0 599.0 2.76 2080.0 1450.0 5.98 6.181 0.9386 3070070 PK04_103286 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(CO)o2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O11 mock treatment 560.0 -41.3 -0.19 1200.0 571.0 2.35 1.5285 0.6476 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O12 mock treatment 720.0 119.0 0.55 680.0 51.1 0.21 0.5364 0.9138 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O13 compound treatment 840.0 239.0 1.1 720.0 91.1 0.38 1.0447 0.8974 3188373 PK04_103287 COCC(=C=CC[C@H](O)c1ccccc1OCCO)C[C@H](O)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O14 compound treatment 4440.0 3840.0 17.72 4040.0 3410.0 14.05 22.4675 0.9934 3188374 PK04_103288 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3ccccc3OCCO)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O15 compound treatment 1880.0 1280.0 5.9 1960.0 1330.0 5.48 8.0516 0.9993 3070071 PK04_103289 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O16 compound treatment 3520.0 2920.0 13.48 2720.0 2090.0 8.61 15.6194 0.9766 3188375 PK04_103290 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccccc2OCCO)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O17 compound treatment 3840.0 3240.0 14.95 4120.0 3490.0 14.38 20.7416 0.9998 3070072 PK04_103291 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2ccc(OCCO)cc2)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O18 compound treatment 3880.0 3280.0 15.14 5080.0 4450.0 18.33 23.6682 0.9955 3188376 PK04_103292 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O19 compound treatment 1880.0 1280.0 5.9 3920.0 3290.0 13.56 13.76 0.9306 3188377 PK04_103293 COCC(=C)/C(=C/C[C@H](OC(=O)C)c1ccc(OCCO)cc1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O20 compound treatment 5400.0 4800.0 22.16 4440.0 3810.0 15.7 26.7667 0.9858 3070073 PK04_103294 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@@H](OC(=O)c2ccncc2)c3cccc(OCCO)c3)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O21 compound treatment 2400.0 1800.0 8.3 2760.0 2130.0 8.78 12.0793 0.9996 3188378 PK04_103295 CCCCC(=C)/C(=C/C[C@H](OC(=O)C)c1cccc(OCCO)c1)/c2cc(ccc2OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O22 compound treatment 2600.0 2000.0 9.23 3000.0 2370.0 9.77 13.4312 0.9996 3188379 PK04_103296 CCCCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2cccc(OCCO)c2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O23 compound treatment 2120.0 1520.0 7.01 2960.0 2330.0 9.6 11.7476 0.9881 3070074 PK04_103297 COC(=O)c1ccc(OC)c(c1)/C(=C\C[C@H](OC(=O)C)c2cccc(OCCO)c2)/C(=C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 O24 compound treatment 1200.0 599.0 2.76 3080.0 2450.0 10.1 9.0934 0.8687 3188380 PK04_103298 COCC(=C)/C(=C/C[C@@H](OC(=O)c1ccncc1)c2ccc(OCCO)cc2)/c3cc(ccc3OC)C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P01 compound treatment 560.0 -41.3 -0.19 680.0 51.1 0.21 0.014 0.0493 3070075 PK04_103299 COCC(=C=CC[C@@H](O)c1ccc(CO)o1)CCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P02 compound treatment 560.0 -41.3 -0.19 840.0 211.0 0.87 0.48 0.5391 3188381 PK04_103300 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P03 compound treatment 1800.0 1200.0 5.53 3440.0 2810.0 11.58 12.1008 0.9429 3188382 PK04_103301 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P04 compound treatment 440.0 -161.0 -0.74 600.0 -28.9 -0.12 -0.6108 -0.8097 3070118 PK04_103302 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P05 compound treatment 1120.0 519.0 2.39 2440.0 1810.0 7.46 6.9683 0.8894 3188383 PK04_103303 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P06 compound treatment 560.0 -41.3 -0.19 600.0 -28.9 -0.12 -0.219 -0.974 3070119 PK04_103304 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P07 compound treatment 2520.0 1920.0 8.86 2000.0 1370.0 5.65 10.2576 0.9764 3188384 PK04_103305 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P08 compound treatment 520.0 -81.3 -0.38 560.0 -68.9 -0.28 -0.4661 -0.9904 3188385 PK04_103306 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P09 compound treatment 1320.0 719.0 3.32 2160.0 1530.0 6.31 6.8058 0.955 3070120 PK04_103307 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P10 compound treatment 600.0 -1.33 -0.01 1000.0 371.0 1.53 1.0766 0.7043 3188386 PK04_103308 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P11 mock treatment 560.0 -41.3 -0.19 1240.0 611.0 2.52 1.645 0.6516 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P12 mock treatment 600.0 -1.33 -0.01 720.0 91.1 0.38 0.2611 0.6954 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P13 compound treatment 1440.0 839.0 3.87 2320.0 1690.0 6.97 7.6635 0.9616 3070121 PK04_103309 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P14 compound treatment 720.0 119.0 0.55 440.0 -189.0 -0.78 -0.1626 -0.1709 3188387 PK04_103310 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P15 compound treatment 1320.0 719.0 3.32 1880.0 1250.0 5.15 5.9903 0.9773 3188388 PK04_103311 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P16 compound treatment 680.0 78.7 0.36 680.0 51.1 0.21 0.4058 0.9664 3070122 PK04_103312 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P17 compound treatment 3120.0 2520.0 11.63 3680.0 3050.0 12.57 17.1094 0.9992 3188389 PK04_103313 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P18 compound treatment 1280.0 679.0 3.13 2000.0 1370.0 5.65 6.2092 0.9614 3188390 PK04_103314 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P19 compound treatment 3800.0 3200.0 14.77 3400.0 2770.0 11.41 18.514 0.9919 3070123 PK04_103315 CC(C)C(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P20 compound treatment 680.0 78.7 0.36 800.0 171.0 0.7 0.7553 0.9524 3188503 PK04_103316 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P21 compound treatment 1640.0 1040.0 4.8 2520.0 1890.0 7.79 8.899 0.9729 3188504 PK04_103317 COCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)COCc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P22 compound treatment 560.0 -41.3 -0.19 640.0 11.1 0.05 -0.1025 -0.5221 3070124 PK04_103318 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P23 compound treatment 2960.0 2360.0 10.89 2880.0 2250.0 9.27 14.2571 0.9968 3188505 PK04_103319 CCCCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2103 P24 compound treatment 1160.0 559.0 2.58 920.0 291.0 1.2 2.6719 0.9393 3188506 PK04_103320 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A01 compound treatment 640.0 127.0 0.59 560.0 33.1 0.14 0.5118 0.8488 3220649 PK04_107001 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A02 compound treatment 400.0 -113.0 -0.52 440.0 -86.9 -0.36 -0.6213 -0.9832 3188507 PK04_107002 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A03 compound treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 3220651 PK04_107003 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A04 compound treatment 560.0 47.2 0.22 440.0 -86.9 -0.36 -0.0989 -0.236 3070126 PK04_107004 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A05 compound treatment 760.0 247.0 1.14 600.0 73.1 0.3 1.0201 0.8641 3220653 PK04_107005 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A06 compound treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 3070127 PK04_107006 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A07 compound treatment 840.0 327.0 1.51 640.0 113.0 0.47 1.3978 0.8841 3220655 PK04_107007 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A08 compound treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 3070128 PK04_107008 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A09 compound treatment 640.0 127.0 0.59 800.0 273.0 1.12 1.2108 0.9541 3220657 PK04_107009 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A10 compound treatment 720.0 207.0 0.96 840.0 313.0 1.29 1.5885 0.9892 3070129 PK04_107010 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A11 compound treatment 720.0 207.0 0.96 840.0 313.0 1.29 1.5885 0.9892 3220659 PK04_107011 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A12 compound treatment 920.0 407.0 1.88 680.0 153.0 0.63 1.7755 0.8953 3188513 PK04_107012 CCCCCCc1nc(CCCc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)cc4CO[Si](C(C)C)(C(C)C)c41 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A13 mock treatment 640.0 127.0 0.59 440.0 -86.9 -0.36 0.1623 0.236 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A14 mock treatment 680.0 167.0 0.77 640.0 113.0 0.47 0.8754 0.9708 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A15 compound treatment 640.0 127.0 0.59 680.0 153.0 0.63 0.8613 0.9994 3220661 PK04_107013 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A16 compound treatment 520.0 7.21 0.03 600.0 73.1 0.3 0.2365 0.7805 3188514 PK04_107014 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A17 compound treatment 800.0 287.0 1.33 720.0 193.0 0.8 1.5002 0.9701 3220663 PK04_107015 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3ccccc3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A18 compound treatment 600.0 87.2 0.4 480.0 -46.9 -0.19 0.1482 0.3319 3070178 PK04_107016 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A19 compound treatment 760.0 247.0 1.14 560.0 33.1 0.14 0.9036 0.786 3220665 PK04_107017 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A20 compound treatment 480.0 -32.8 -0.15 600.0 73.1 0.3 0.1059 0.3142 3070179 PK04_107018 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A21 compound treatment 680.0 167.0 0.77 800.0 273.0 1.12 1.3414 0.9831 3220667 PK04_107019 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A22 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3070180 PK04_107020 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A23 compound treatment 720.0 207.0 0.96 640.0 113.0 0.47 1.006 0.9453 3220669 PK04_107021 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 A24 compound treatment 520.0 7.21 0.03 600.0 73.1 0.3 0.2365 0.7805 3070181 PK04_107022 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B01 compound treatment 560.0 47.2 0.22 640.0 113.0 0.47 0.4836 0.9401 3188518 PK04_107023 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B02 compound treatment 480.0 -32.8 -0.15 360.0 -167.0 -0.69 -0.5931 -0.8426 3188519 PK04_107024 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B03 compound treatment 440.0 -72.8 -0.34 600.0 73.1 0.3 -0.0247 -0.0547 3070182 PK04_107025 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B04 compound treatment 480.0 -32.8 -0.15 320.0 -207.0 -0.85 -0.7096 -0.8199 3188520 PK04_107026 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B05 compound treatment 560.0 47.2 0.22 520.0 -6.88 -0.03 0.1341 0.6101 3188521 PK04_107027 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B06 compound treatment 720.0 207.0 0.96 400.0 -127.0 -0.52 0.307 0.2816 3070183 PK04_107028 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B07 compound treatment 480.0 -32.8 -0.15 680.0 153.0 0.63 0.3389 0.5225 3188640 PK04_107029 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B08 compound treatment 440.0 -72.8 -0.34 520.0 -6.88 -0.03 -0.2577 -0.764 3188641 PK04_107030 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B09 compound treatment 800.0 287.0 1.33 600.0 73.1 0.3 1.1507 0.8462 3070184 PK04_107031 COc1ccc(CC(=O)N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B10 compound treatment 400.0 -113.0 -0.52 560.0 33.1 0.14 -0.2718 -0.5048 3188642 PK04_107032 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B11 compound treatment 520.0 7.21 0.03 680.0 153.0 0.63 0.4695 0.7434 3070185 PK04_107033 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B12 compound treatment 640.0 127.0 0.59 480.0 -46.9 -0.19 0.2788 0.4509 3188643 PK04_107034 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B13 mock treatment 640.0 127.0 0.59 520.0 -6.88 -0.03 0.3953 0.6722 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B14 mock treatment 480.0 -32.8 -0.15 400.0 -127.0 -0.52 -0.4766 -0.8759 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B15 compound treatment 880.0 367.0 1.7 600.0 73.1 0.3 1.4119 0.8199 3188644 PK04_107035 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B16 compound treatment 1520.0 1010.0 4.65 720.0 193.0 0.8 3.8509 0.8162 3070186 PK04_107036 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B17 compound treatment 760.0 247.0 1.14 680.0 153.0 0.63 1.2531 0.9609 3188645 PK04_107037 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B18 compound treatment 680.0 167.0 0.77 680.0 153.0 0.63 0.9919 0.995 3188646 PK04_107038 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B19 compound treatment 1440.0 927.0 4.28 1040.0 513.0 2.11 4.5217 0.9471 3070187 PK04_107039 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B20 compound treatment 960.0 447.0 2.06 920.0 393.0 1.62 2.605 0.9928 3188647 PK04_107040 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B21 compound treatment 920.0 407.0 1.88 920.0 393.0 1.62 2.4745 0.9972 3188648 PK04_107041 COc1ccc(CC(=O)N(Cc2cc3ccccc3o2)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B22 compound treatment 800.0 287.0 1.33 680.0 153.0 0.63 1.3837 0.9423 3070188 PK04_107042 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B23 compound treatment 920.0 407.0 1.88 680.0 153.0 0.63 1.7755 0.8953 3188649 PK04_107043 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 B24 compound treatment 720.0 207.0 0.96 800.0 273.0 1.12 1.472 0.9968 3188650 PK04_107044 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C01 compound treatment 640.0 127.0 0.59 520.0 -6.88 -0.03 0.3953 0.6722 3414054 PK04_107045 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C02 compound treatment 520.0 7.21 0.03 480.0 -46.9 -0.19 -0.113 -0.5766 3188651 PK04_107046 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C03 compound treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 3414055 PK04_107047 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C04 compound treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 3070235 PK04_107048 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C05 compound treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 3414056 PK04_107049 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C06 compound treatment 720.0 207.0 0.96 560.0 33.1 0.14 0.773 0.7999 3070236 PK04_107050 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C07 compound treatment 480.0 -32.8 -0.15 720.0 193.0 0.8 0.4554 0.5624 3414057 PK04_107051 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C08 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3188655 PK04_107052 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C09 compound treatment 720.0 207.0 0.96 640.0 113.0 0.47 1.006 0.9453 3220705 PK04_107053 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C10 compound treatment 560.0 47.2 0.22 520.0 -6.88 -0.03 0.1341 0.6101 3188656 PK04_107054 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C11 mock treatment 680.0 167.0 0.77 600.0 73.1 0.3 0.7589 0.9157 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C12 mock treatment 440.0 -72.8 -0.34 520.0 -6.88 -0.03 -0.2577 -0.764 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C13 compound treatment 640.0 127.0 0.59 720.0 193.0 0.8 0.9778 0.9889 3220708 PK04_107055 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C14 compound treatment 480.0 -32.8 -0.15 560.0 33.1 0.14 -0.0106 -0.0519 3188772 PK04_107056 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C15 mock treatment 840.0 327.0 1.51 480.0 -46.9 -0.19 0.9318 0.6118 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C16 mock treatment 520.0 7.21 0.03 360.0 -167.0 -0.69 -0.4625 -0.6721 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C17 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3220711 PK04_107057 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C18 compound treatment 560.0 47.2 0.22 640.0 113.0 0.47 0.4836 0.9401 3070242 PK04_107058 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C19 compound treatment 840.0 327.0 1.51 1480.0 953.0 3.93 3.8442 0.9139 3220713 PK04_107059 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C20 compound treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 3070245 PK04_107060 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C21 compound treatment 800.0 287.0 1.33 720.0 193.0 0.8 1.5002 0.9701 3220715 PK04_107061 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C22 compound treatment 520.0 7.21 0.03 480.0 -46.9 -0.19 -0.113 -0.5766 3070527 PK04_107062 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C23 compound treatment 680.0 167.0 0.77 520.0 -6.88 -0.03 0.5259 0.6807 3220717 PK04_107063 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 C24 compound treatment 480.0 -32.8 -0.15 680.0 153.0 0.63 0.3389 0.5225 3070530 PK04_107064 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D01 compound treatment 640.0 127.0 0.59 400.0 -127.0 -0.52 0.0458 0.0583 3188777 PK04_107065 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D02 compound treatment 360.0 -153.0 -0.71 320.0 -207.0 -0.85 -1.1013 -0.9956 3188778 PK04_107066 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D03 compound treatment 400.0 -113.0 -0.52 360.0 -167.0 -0.69 -0.8542 -0.9906 3070575 PK04_107067 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D04 compound treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 3188779 PK04_107068 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D05 compound treatment 440.0 -72.8 -0.34 480.0 -46.9 -0.19 -0.3742 -0.9654 3188780 PK04_107069 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D06 compound treatment 600.0 87.2 0.4 520.0 -6.88 -0.03 0.2647 0.6558 3070579 PK04_107070 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D07 compound treatment 480.0 -32.8 -0.15 600.0 73.1 0.3 0.1059 0.3142 3188781 PK04_107071 COc1ccc(CC(=O)N(Cc2cccc3ccccc23)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D08 compound treatment 520.0 7.21 0.03 480.0 -46.9 -0.19 -0.113 -0.5766 3188782 PK04_107072 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D09 compound treatment 680.0 167.0 0.77 560.0 33.1 0.14 0.6424 0.8194 3188783 PK04_107073 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc(OC)cc5)c6ccc(OCCCO)cc46)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D10 compound treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 3070632 PK04_107074 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5cccc6ccccc56)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D11 mock treatment 480.0 -32.8 -0.15 680.0 153.0 0.63 0.3389 0.5225 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D12 mock treatment 520.0 7.21 0.03 480.0 -46.9 -0.19 -0.113 -0.5766 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D13 compound treatment 760.0 247.0 1.14 720.0 193.0 0.8 1.3696 0.9844 3188784 PK04_107075 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D14 compound treatment 400.0 -113.0 -0.52 600.0 73.1 0.3 -0.1553 -0.2581 3188785 PK04_107076 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D15 mock treatment 560.0 47.2 0.22 640.0 113.0 0.47 0.4836 0.9401 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D16 mock treatment 720.0 207.0 0.96 560.0 33.1 0.14 0.773 0.7999 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D17 compound treatment 640.0 127.0 0.59 640.0 113.0 0.47 0.7448 0.9934 3070637 PK04_107077 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)Cc5ccc6ccccc6c5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D18 compound treatment 720.0 207.0 0.96 440.0 -86.9 -0.36 0.4235 0.4146 3188786 PK04_107078 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D19 compound treatment 680.0 167.0 0.77 480.0 -46.9 -0.19 0.4094 0.5144 3188787 PK04_107079 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc6ccccc6n5)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D20 compound treatment 880.0 367.0 1.7 720.0 193.0 0.8 1.7614 0.9405 3070641 PK04_107080 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D21 compound treatment 680.0 167.0 0.77 800.0 273.0 1.12 1.3414 0.9831 3188905 PK04_107081 COc1ccc(CC(=O)N(Cc2ccc(cc2)c3ccccc3)[C@@H]4[C@@H](C(CC=C)OC(=O)C)N(C(=O)c5ccc(cc5)c6ccccc6)c7ccc(OCCCO)cc47)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D22 compound treatment 560.0 47.2 0.22 680.0 153.0 0.63 0.6001 0.8993 3188906 PK04_107082 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4cccc5ccccc45)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D23 compound treatment 800.0 287.0 1.33 680.0 153.0 0.63 1.3837 0.9423 3070684 PK04_107083 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 D24 compound treatment 560.0 47.2 0.22 560.0 33.1 0.14 0.2506 0.9745 3188907 PK04_107084 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E01 mock treatment 440.0 -72.8 -0.34 720.0 193.0 0.8 0.3248 0.3762 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E02 mock treatment 400.0 -113.0 -0.52 640.0 113.0 0.47 -0.0388 -0.0555 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E03 compound treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 3220739 PK04_107085 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E04 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3070690 PK04_107086 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E05 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3220741 PK04_107087 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E06 compound treatment 440.0 -72.8 -0.34 560.0 33.1 0.14 -0.1412 -0.3892 3070694 PK04_107088 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E07 compound treatment 520.0 7.21 0.03 600.0 73.1 0.3 0.2365 0.7805 3220743 PK04_107089 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E08 compound treatment 560.0 47.2 0.22 560.0 33.1 0.14 0.2506 0.9745 3188910 PK04_107090 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E09 mock treatment 640.0 127.0 0.59 680.0 153.0 0.63 0.8613 0.9994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E10 mock treatment 480.0 -32.8 -0.15 680.0 153.0 0.63 0.3389 0.5225 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E11 compound treatment 400.0 -113.0 -0.52 520.0 -6.88 -0.03 -0.3883 -0.7445 3188911 PK04_107091 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E12 compound treatment 600.0 87.2 0.4 480.0 -46.9 -0.19 0.1482 0.3319 3070742 PK04_107092 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E13 compound treatment 520.0 7.21 0.03 720.0 193.0 0.8 0.586 0.7361 3188912 PK04_107093 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E14 compound treatment 600.0 87.2 0.4 400.0 -127.0 -0.52 -0.0848 -0.1285 3070746 PK04_107094 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E15 compound treatment 600.0 87.2 0.4 480.0 -46.9 -0.19 0.1482 0.3319 3188913 PK04_107095 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E16 compound treatment 480.0 -32.8 -0.15 520.0 -6.88 -0.03 -0.1271 -0.8251 3070750 PK04_107096 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E17 mock treatment 600.0 87.2 0.4 520.0 -6.88 -0.03 0.2647 0.6558 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E18 mock treatment 840.0 327.0 1.51 440.0 -86.9 -0.36 0.8153 0.5251 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E19 compound treatment 760.0 247.0 1.14 600.0 73.1 0.3 1.0201 0.8641 3220747 PK04_107097 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E20 compound treatment 520.0 7.21 0.03 480.0 -46.9 -0.19 -0.113 -0.5766 3188915 PK04_107098 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E21 compound treatment 1000.0 487.0 2.25 880.0 353.0 1.45 2.6191 0.9777 3220749 PK04_107099 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E22 compound treatment 560.0 47.2 0.22 680.0 153.0 0.63 0.6001 0.8993 3070803 PK04_107100 CC(C)[Si](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)(C#Cc3ccc(Oc4ccccc4)cc3)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E23 compound treatment 2240.0 1730.0 7.97 1880.0 1350.0 5.57 9.58 0.9847 3220751 PK04_107101 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 E24 compound treatment 560.0 47.2 0.22 480.0 -46.9 -0.19 0.0176 0.0605 3070808 PK04_107102 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F01 mock treatment 400.0 -113.0 -0.52 480.0 -46.9 -0.19 -0.5048 -0.9088 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F02 mock treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F03 compound treatment 480.0 -32.8 -0.15 400.0 -127.0 -0.52 -0.4766 -0.8759 3188918 PK04_107103 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F04 compound treatment 400.0 -113.0 -0.52 480.0 -46.9 -0.19 -0.5048 -0.9088 3188919 PK04_107104 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F05 compound treatment 480.0 -32.8 -0.15 760.0 233.0 0.96 0.5719 0.5884 3188920 PK04_107105 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F06 compound treatment 480.0 -32.8 -0.15 400.0 -127.0 -0.52 -0.4766 -0.8759 3188921 PK04_107106 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F07 compound treatment 480.0 -32.8 -0.15 640.0 113.0 0.47 0.2224 0.454 3070852 PK04_107107 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F08 compound treatment 400.0 -113.0 -0.52 840.0 313.0 1.29 0.5437 0.3909 3188922 PK04_107108 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F09 mock treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F10 mock treatment 480.0 -32.8 -0.15 680.0 153.0 0.63 0.3389 0.5225 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F11 compound treatment 560.0 47.2 0.22 480.0 -46.9 -0.19 0.0176 0.0605 3189029 PK04_107109 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F12 compound treatment 440.0 -72.8 -0.34 360.0 -167.0 -0.69 -0.7237 -0.9458 3070859 PK04_107110 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F13 compound treatment 640.0 127.0 0.59 760.0 233.0 0.96 1.0943 0.9722 3189030 PK04_107111 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F14 compound treatment 440.0 -72.8 -0.34 600.0 73.1 0.3 -0.0247 -0.0547 3189031 PK04_107112 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F15 compound treatment 680.0 167.0 0.77 760.0 233.0 0.96 1.2249 0.9942 3070862 PK04_107113 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F16 compound treatment 520.0 7.21 0.03 680.0 153.0 0.63 0.4695 0.7434 3189032 PK04_107114 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F17 mock treatment 520.0 7.21 0.03 560.0 33.1 0.14 0.12 0.8546 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F18 mock treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F19 compound treatment 800.0 287.0 1.33 840.0 313.0 1.29 1.8497 0.9999 3189033 PK04_107115 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F20 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3070022 PK04_107116 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F21 compound treatment 880.0 367.0 1.7 960.0 433.0 1.78 2.4604 0.9997 3189034 PK04_107117 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F22 compound treatment 720.0 207.0 0.96 560.0 33.1 0.14 0.773 0.7999 3189035 PK04_107118 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F23 compound treatment 560.0 47.2 0.22 680.0 153.0 0.63 0.6001 0.8993 3070031 PK04_107119 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 F24 compound treatment 720.0 207.0 0.96 520.0 -6.88 -0.03 0.6565 0.6859 3189036 PK04_107120 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G01 compound treatment 440.0 -72.8 -0.34 1080.0 553.0 2.28 1.3733 0.5963 3220772 PK04_107121 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G02 compound treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 3070078 PK04_107122 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G03 mock treatment 520.0 7.21 0.03 600.0 73.1 0.3 0.2365 0.7805 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G04 mock treatment 640.0 127.0 0.59 400.0 -127.0 -0.52 0.0458 0.0583 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G05 compound treatment 480.0 -32.8 -0.15 560.0 33.1 0.14 -0.0106 -0.0519 3220775 PK04_107123 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G06 compound treatment 320.0 -193.0 -0.89 440.0 -86.9 -0.36 -0.8824 -0.9198 3070081 PK04_107124 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G07 compound treatment 960.0 447.0 2.06 560.0 33.1 0.14 1.5566 0.7522 3189039 PK04_107125 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G08 compound treatment 720.0 207.0 0.96 480.0 -46.9 -0.19 0.54 0.5533 3189040 PK04_107126 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G09 compound treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 3070086 PK04_107127 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G10 compound treatment 440.0 -72.8 -0.34 400.0 -127.0 -0.52 -0.6072 -0.9772 3189041 PK04_107128 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G11 compound treatment 560.0 47.2 0.22 560.0 33.1 0.14 0.2506 0.9745 3070089 PK04_107129 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G12 compound treatment 320.0 -193.0 -0.89 360.0 -167.0 -0.69 -1.1154 -0.9918 3189042 PK04_107130 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G13 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3070134 PK04_107131 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G14 compound treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 3070137 PK04_107132 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G15 compound treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 3189043 PK04_107133 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G16 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3189044 PK04_107134 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G17 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3070143 PK04_107135 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G18 compound treatment 440.0 -72.8 -0.34 520.0 -6.88 -0.03 -0.2577 -0.764 3189045 PK04_107136 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G19 mock treatment 600.0 87.2 0.4 560.0 33.1 0.14 0.3812 0.8966 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G20 mock treatment 360.0 -153.0 -0.71 480.0 -46.9 -0.19 -0.6353 -0.8687 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G21 compound treatment 600.0 87.2 0.4 560.0 33.1 0.14 0.3812 0.8966 3070191 PK04_107137 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G22 compound treatment 440.0 -72.8 -0.34 600.0 73.1 0.3 -0.0247 -0.0547 3189046 PK04_107138 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G23 compound treatment 600.0 87.2 0.4 360.0 -167.0 -0.69 -0.2013 -0.2527 3070196 PK04_107139 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 G24 compound treatment 520.0 7.21 0.03 560.0 33.1 0.14 0.12 0.8546 3189047 PK04_107140 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H01 compound treatment 440.0 -72.8 -0.34 440.0 -86.9 -0.36 -0.4907 -0.9995 3189157 PK04_107141 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H02 compound treatment 280.0 -233.0 -1.07 440.0 -86.9 -0.36 -1.013 -0.8943 3189158 PK04_107142 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H03 mock treatment 440.0 -72.8 -0.34 560.0 33.1 0.14 -0.1412 -0.3892 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H04 mock treatment 400.0 -113.0 -0.52 400.0 -127.0 -0.52 -0.7378 -1.0 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H05 compound treatment 480.0 -32.8 -0.15 640.0 113.0 0.47 0.2224 0.454 3070201 PK04_107143 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H06 compound treatment 560.0 47.2 0.22 320.0 -207.0 -0.85 -0.4484 -0.5098 3189159 PK04_107144 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H07 compound treatment 440.0 -72.8 -0.34 560.0 33.1 0.14 -0.1412 -0.3892 3071172 PK04_107145 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H08 compound treatment 400.0 -113.0 -0.52 600.0 73.1 0.3 -0.1553 -0.2581 3071173 PK04_107146 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H09 compound treatment 480.0 -32.8 -0.15 600.0 73.1 0.3 0.1059 0.3142 3071174 PK04_107147 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H10 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3189160 PK04_107148 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H11 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3189161 PK04_107149 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H12 compound treatment 320.0 -193.0 -0.89 440.0 -86.9 -0.36 -0.8824 -0.9198 3071175 PK04_107150 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H13 compound treatment 440.0 -72.8 -0.34 600.0 73.1 0.3 -0.0247 -0.0547 3189162 PK04_107151 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(cc5)c6ccccc6)c7cc(OCCCO)ccc27)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H14 compound treatment 360.0 -153.0 -0.71 680.0 153.0 0.63 -0.0529 -0.0559 3189163 PK04_107152 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H15 compound treatment 520.0 7.21 0.03 440.0 -86.9 -0.36 -0.2295 -0.6385 3071176 PK04_107153 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H16 compound treatment 520.0 7.21 0.03 440.0 -86.9 -0.36 -0.2295 -0.6385 3189164 PK04_107154 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H17 compound treatment 440.0 -72.8 -0.34 680.0 153.0 0.63 0.2083 0.2915 3189165 PK04_107155 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc8ccccc8c7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H18 compound treatment 480.0 -32.8 -0.15 360.0 -167.0 -0.69 -0.5931 -0.8426 3071177 PK04_107156 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H19 mock treatment 680.0 167.0 0.77 840.0 313.0 1.29 1.4579 0.9699 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H20 mock treatment 440.0 -72.8 -0.34 480.0 -46.9 -0.19 -0.3742 -0.9654 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H21 compound treatment 680.0 167.0 0.77 680.0 153.0 0.63 0.9919 0.995 3189166 PK04_107157 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H22 compound treatment 280.0 -233.0 -1.07 400.0 -127.0 -0.52 -1.1295 -0.9451 3189167 PK04_107158 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccccc2c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H23 compound treatment 440.0 -72.8 -0.34 600.0 73.1 0.3 -0.0247 -0.0547 3071178 PK04_107159 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc(cc7)c8ccccc8 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 H24 compound treatment 560.0 47.2 0.22 1680.0 1150.0 4.75 3.5126 0.7388 3189168 PK04_107160 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I01 compound treatment 520.0 7.21 0.03 440.0 -86.9 -0.36 -0.2295 -0.6385 3071179 PK04_107161 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I02 compound treatment 480.0 -32.8 -0.15 520.0 -6.88 -0.03 -0.1271 -0.8251 3189169 PK04_107162 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I03 compound treatment 480.0 -32.8 -0.15 800.0 273.0 1.12 0.6884 0.6065 3071180 PK04_107163 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I04 compound treatment 560.0 47.2 0.22 440.0 -86.9 -0.36 -0.0989 -0.236 3189170 PK04_107164 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I05 mock treatment 520.0 7.21 0.03 680.0 153.0 0.63 0.4695 0.7434 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I06 mock treatment 560.0 47.2 0.22 720.0 193.0 0.8 0.7166 0.8689 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I07 compound treatment 480.0 -32.8 -0.15 640.0 113.0 0.47 0.2224 0.454 3071181 PK04_107165 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I08 compound treatment 600.0 87.2 0.4 480.0 -46.9 -0.19 0.1482 0.3319 3189171 PK04_107166 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I09 compound treatment 800.0 287.0 1.33 760.0 233.0 0.96 1.6167 0.9874 3189172 PK04_107167 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I10 compound treatment 520.0 7.21 0.03 680.0 153.0 0.63 0.4695 0.7434 3071182 PK04_107168 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I11 compound treatment 560.0 47.2 0.22 440.0 -86.9 -0.36 -0.0989 -0.236 3189173 PK04_107169 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I12 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3189286 PK04_107170 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I13 compound treatment 880.0 367.0 1.7 800.0 273.0 1.12 1.9944 0.9801 3071183 PK04_107171 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I14 compound treatment 400.0 -113.0 -0.52 560.0 33.1 0.14 -0.2718 -0.5048 3189287 PK04_107172 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I15 compound treatment 640.0 127.0 0.59 720.0 193.0 0.8 0.9778 0.9889 3071184 PK04_107173 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I16 compound treatment 1200.0 687.0 3.17 1360.0 833.0 3.43 4.6701 0.9992 3189288 PK04_107174 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I17 compound treatment 520.0 7.21 0.03 600.0 73.1 0.3 0.2365 0.7805 3071185 PK04_107175 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I18 compound treatment 680.0 167.0 0.77 640.0 113.0 0.47 0.8754 0.9708 3189289 PK04_107176 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I19 compound treatment 600.0 87.2 0.4 840.0 313.0 1.29 1.1967 0.8857 3071186 PK04_107177 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I20 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3189171 PK04_107178 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I21 mock treatment 800.0 287.0 1.33 560.0 33.1 0.14 1.0342 0.7758 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I22 mock treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I23 compound treatment 800.0 287.0 1.33 800.0 273.0 1.12 1.7332 0.9966 3189290 PK04_107179 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 I24 compound treatment 600.0 87.2 0.4 680.0 153.0 0.63 0.7307 0.9765 3071182 PK04_107180 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J01 compound treatment 520.0 7.21 0.03 600.0 73.1 0.3 0.2365 0.7805 3189291 PK04_107181 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J02 compound treatment 480.0 -32.8 -0.15 920.0 393.0 1.62 1.0379 0.6382 3071187 PK04_107182 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J03 compound treatment 640.0 127.0 0.59 480.0 -46.9 -0.19 0.2788 0.4509 3189292 PK04_107183 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J04 compound treatment 520.0 7.21 0.03 400.0 -127.0 -0.52 -0.346 -0.6607 3189293 PK04_107184 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J05 mock treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J06 mock treatment 520.0 7.21 0.03 560.0 33.1 0.14 0.12 0.8546 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J07 compound treatment 440.0 -72.8 -0.34 480.0 -46.9 -0.19 -0.3742 -0.9654 3071188 PK04_107185 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J08 compound treatment 720.0 207.0 0.96 800.0 273.0 1.12 1.472 0.9968 3189294 PK04_107186 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J09 compound treatment 560.0 47.2 0.22 520.0 -6.88 -0.03 0.1341 0.6101 3189295 PK04_107187 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J10 compound treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 3071189 PK04_107188 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J11 compound treatment 560.0 47.2 0.22 680.0 153.0 0.63 0.6001 0.8993 3189296 PK04_107189 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J12 compound treatment 400.0 -113.0 -0.52 680.0 153.0 0.63 0.0777 0.095 3189297 PK04_107190 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J13 compound treatment 800.0 287.0 1.33 640.0 113.0 0.47 1.2672 0.9015 3071190 PK04_107191 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J14 compound treatment 520.0 7.21 0.03 520.0 -6.88 -0.03 0.0035 0.0807 3189298 PK04_107192 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J15 compound treatment 960.0 447.0 2.06 920.0 393.0 1.62 2.605 0.9928 3071191 PK04_107193 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J16 compound treatment 1080.0 567.0 2.62 600.0 73.1 0.3 2.0648 0.7833 3189299 PK04_107194 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J17 compound treatment 800.0 287.0 1.33 920.0 393.0 1.62 2.0827 0.9951 3189300 PK04_107195 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J18 compound treatment 1120.0 607.0 2.8 880.0 353.0 1.45 3.0109 0.9533 3071192 PK04_107196 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J19 compound treatment 1200.0 687.0 3.17 840.0 313.0 1.29 3.1556 0.9213 3189301 PK04_107197 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J20 compound treatment 1040.0 527.0 2.43 880.0 353.0 1.45 2.7497 0.9697 3189302 PK04_107198 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J21 mock treatment 360.0 -153.0 -0.71 760.0 233.0 0.96 0.1801 0.1512 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J22 mock treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J23 compound treatment 760.0 247.0 1.14 520.0 -6.88 -0.03 0.7871 0.6894 3071251 PK04_107199 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 J24 compound treatment 960.0 447.0 2.06 760.0 233.0 0.96 2.1391 0.9393 3189414 PK04_107200 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K01 compound treatment 400.0 -113.0 -0.52 400.0 -127.0 -0.52 -0.7378 -1.0 3071252 PK04_107201 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K02 compound treatment 520.0 7.21 0.03 640.0 113.0 0.47 0.353 0.7557 3189415 PK04_107202 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K03 compound treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 3071253 PK04_107203 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K04 compound treatment 440.0 -72.8 -0.34 480.0 -46.9 -0.19 -0.3742 -0.9654 3189416 PK04_107204 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K05 compound treatment 400.0 -113.0 -0.52 360.0 -167.0 -0.69 -0.8542 -0.9906 3189417 PK04_107205 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K06 compound treatment 440.0 -72.8 -0.34 520.0 -6.88 -0.03 -0.2577 -0.764 3071254 PK04_107206 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K07 mock treatment 520.0 7.21 0.03 640.0 113.0 0.47 0.353 0.7557 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K08 mock treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K09 compound treatment 440.0 -72.8 -0.34 600.0 73.1 0.3 -0.0247 -0.0547 3071255 PK04_107207 NC(=N)NCC#C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K10 compound treatment 360.0 -153.0 -0.71 360.0 -167.0 -0.69 -0.9848 -0.9999 3189418 PK04_107208 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K11 compound treatment 720.0 207.0 0.96 520.0 -6.88 -0.03 0.6565 0.6859 3189419 PK04_107209 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K12 compound treatment 600.0 87.2 0.4 600.0 73.1 0.3 0.4977 0.9898 3071256 PK04_107210 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K13 compound treatment 960.0 447.0 2.06 960.0 433.0 1.78 2.7215 0.9973 3189420 PK04_107211 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K14 compound treatment 400.0 -113.0 -0.52 400.0 -127.0 -0.52 -0.7378 -1.0 3071257 PK04_107212 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K15 mock treatment 600.0 87.2 0.4 560.0 33.1 0.14 0.3812 0.8966 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K16 mock treatment 440.0 -72.8 -0.34 520.0 -6.88 -0.03 -0.2577 -0.764 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K17 compound treatment 320.0 -193.0 -0.89 440.0 -86.9 -0.36 -0.8824 -0.9198 1035256 PK04_107213 C#CCNCc1ccccc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K18 compound treatment 360.0 -153.0 -0.71 520.0 -6.88 -0.03 -0.5188 -0.7349 3189421 PK04_107214 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K19 compound treatment 440.0 -72.8 -0.34 640.0 113.0 0.47 0.0918 0.1599 3071258 PK04_107215 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K20 compound treatment 360.0 -153.0 -0.71 400.0 -127.0 -0.52 -0.8683 -0.9891 3189422 PK04_107216 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K21 compound treatment 560.0 47.2 0.22 680.0 153.0 0.63 0.6001 0.8993 3189423 PK04_107217 [N-]=[N+]=NC[C@H](Cc1ccccc1)NC(=O)c2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K22 compound treatment 360.0 -153.0 -0.71 480.0 -46.9 -0.19 -0.6353 -0.8687 3071259 PK04_107218 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K23 mock treatment 520.0 7.21 0.03 480.0 -46.9 -0.19 -0.113 -0.5766 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 K24 mock treatment 440.0 -72.8 -0.34 560.0 33.1 0.14 -0.1412 -0.3892 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L01 compound treatment 520.0 7.21 0.03 320.0 -207.0 -0.85 -0.579 -0.679 3189424 PK04_107219 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L02 compound treatment 560.0 47.2 0.22 400.0 -127.0 -0.52 -0.2154 -0.3804 3189425 PK04_107220 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L03 compound treatment 440.0 -72.8 -0.34 360.0 -167.0 -0.69 -0.7237 -0.9458 3071260 PK04_107221 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L04 compound treatment 360.0 -153.0 -0.71 480.0 -46.9 -0.19 -0.6353 -0.8687 3189426 PK04_107222 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L05 compound treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 3189427 PK04_107223 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L06 compound treatment 560.0 47.2 0.22 440.0 -86.9 -0.36 -0.0989 -0.236 3071261 PK04_107224 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L07 mock treatment 480.0 -32.8 -0.15 400.0 -127.0 -0.52 -0.4766 -0.8759 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L08 mock treatment 400.0 -113.0 -0.52 240.0 -287.0 -1.18 -1.2037 -0.9322 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L09 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3189428 PK04_107225 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L10 compound treatment 720.0 207.0 0.96 720.0 193.0 0.8 1.239 0.9958 3189429 PK04_107226 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L11 compound treatment 960.0 447.0 2.06 520.0 -6.88 -0.03 1.4401 0.6973 3071262 PK04_107227 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L12 compound treatment 600.0 87.2 0.4 680.0 153.0 0.63 0.7307 0.9765 3189430 PK04_107228 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L13 compound treatment 760.0 247.0 1.14 680.0 153.0 0.63 1.2531 0.9609 3189431 PK04_107229 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)Cc5ccc(F)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L14 compound treatment 1320.0 807.0 3.73 880.0 353.0 1.45 3.6639 0.9158 3071263 PK04_107230 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L15 mock treatment 1000.0 487.0 2.25 400.0 -127.0 -0.52 1.2212 0.5288 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L16 mock treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L17 compound treatment 520.0 7.21 0.03 800.0 273.0 1.12 0.819 0.7277 3189432 PK04_107231 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L18 compound treatment 640.0 127.0 0.59 640.0 113.0 0.47 0.7448 0.9934 3189547 PK04_107232 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L19 compound treatment 560.0 47.2 0.22 600.0 73.1 0.3 0.3671 0.9874 3071264 PK04_107233 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L20 compound treatment 1040.0 527.0 2.43 640.0 113.0 0.47 2.0507 0.8274 3189548 PK04_107234 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L21 compound treatment 1120.0 607.0 2.8 640.0 113.0 0.47 2.3119 0.8135 3189549 PK04_107235 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L22 compound treatment 480.0 -32.8 -0.15 480.0 -46.9 -0.19 -0.2436 -0.9928 3071265 PK04_107236 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L23 mock treatment 480.0 -32.8 -0.15 560.0 33.1 0.14 -0.0106 -0.0519 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 L24 mock treatment 480.0 -32.8 -0.15 520.0 -6.88 -0.03 -0.1271 -0.8251 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M01 compound treatment 400.0 -113.0 -0.52 840.0 313.0 1.29 0.5437 0.3909 3189550 PK04_107237 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M02 compound treatment 560.0 47.2 0.22 440.0 -86.9 -0.36 -0.0989 -0.236 3071266 PK04_107238 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M03 compound treatment 360.0 -153.0 -0.71 920.0 393.0 1.62 0.6461 0.3658 3189551 PK04_107239 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M04 compound treatment 360.0 -153.0 -0.71 440.0 -86.9 -0.36 -0.7518 -0.9505 3189552 PK04_107240 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M05 compound treatment 320.0 -193.0 -0.89 440.0 -86.9 -0.36 -0.8824 -0.9198 3071267 PK04_107241 CN(C)S(=O)(=O)NCC#C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M06 compound treatment 440.0 -72.8 -0.34 400.0 -127.0 -0.52 -0.6072 -0.9772 3189553 PK04_107242 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M07 compound treatment 560.0 47.2 0.22 480.0 -46.9 -0.19 0.0176 0.0605 3414058 PK04_107243 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M08 compound treatment 400.0 -113.0 -0.52 560.0 33.1 0.14 -0.2718 -0.5048 3189554 PK04_107244 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M09 mock treatment 440.0 -72.8 -0.34 320.0 -207.0 -0.85 -0.8402 -0.9172 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M10 mock treatment 480.0 -32.8 -0.15 600.0 73.1 0.3 0.1059 0.3142 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M11 compound treatment 320.0 -193.0 -0.89 520.0 -6.88 -0.03 -0.6494 -0.7292 3189555 PK04_107245 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M12 compound treatment 440.0 -72.8 -0.34 480.0 -46.9 -0.19 -0.3742 -0.9654 3071269 PK04_107246 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M13 mock treatment 800.0 287.0 1.33 560.0 33.1 0.14 1.0342 0.7758 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M14 mock treatment 360.0 -153.0 -0.71 320.0 -207.0 -0.85 -1.1013 -0.9956 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M15 compound treatment 600.0 87.2 0.4 520.0 -6.88 -0.03 0.2647 0.6558 3189556 PK04_107247 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M16 compound treatment 440.0 -72.8 -0.34 480.0 -46.9 -0.19 -0.3742 -0.9654 3189557 PK04_107248 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M17 compound treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 3189558 PK04_107249 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M18 compound treatment 400.0 -113.0 -0.52 520.0 -6.88 -0.03 -0.3883 -0.7445 3071329 PK04_107250 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M19 compound treatment 560.0 47.2 0.22 560.0 33.1 0.14 0.2506 0.9745 3189559 PK04_107251 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M20 compound treatment 400.0 -113.0 -0.52 480.0 -46.9 -0.19 -0.5048 -0.9088 3071330 PK04_107252 CCCC#C[Si](O[C@H](CC)c1cn(Cc2cccc(Cl)c2)nn1)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M21 compound treatment 400.0 -113.0 -0.52 440.0 -86.9 -0.36 -0.6213 -0.9832 3189560 PK04_107253 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M22 compound treatment 400.0 -113.0 -0.52 440.0 -86.9 -0.36 -0.6213 -0.9832 3071331 PK04_107254 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M23 compound treatment 560.0 47.2 0.22 360.0 -167.0 -0.69 -0.3319 -0.4603 3189561 PK04_107255 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 M24 compound treatment 320.0 -193.0 -0.89 320.0 -207.0 -0.85 -1.2319 -0.9998 3071332 PK04_107256 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N01 compound treatment 320.0 -193.0 -0.89 320.0 -207.0 -0.85 -1.2319 -0.9998 3189562 PK04_107257 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)Cc4ccc(F)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N02 compound treatment 400.0 -113.0 -0.52 400.0 -127.0 -0.52 -0.7378 -1.0 3189563 PK04_107258 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N03 compound treatment 480.0 -32.8 -0.15 400.0 -127.0 -0.52 -0.4766 -0.8759 3071333 PK04_107259 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(o3)c4cccc(c4)C(F)(F)F)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N04 compound treatment 560.0 47.2 0.22 400.0 -127.0 -0.52 -0.2154 -0.3804 3189564 PK04_107260 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N05 compound treatment 360.0 -153.0 -0.71 520.0 -6.88 -0.03 -0.5188 -0.7349 3189681 PK04_107261 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N06 compound treatment 520.0 7.21 0.03 680.0 153.0 0.63 0.4695 0.7434 3071334 PK04_107262 CCOC(=O)C[C@H]1[C@H](OC(=O)c2ccc(cc2)C(=O)c3ccccc3)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccc6ccccc6n5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N07 compound treatment 360.0 -153.0 -0.71 320.0 -207.0 -0.85 -1.1013 -0.9956 3189682 PK04_107263 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N08 compound treatment 640.0 127.0 0.59 560.0 33.1 0.14 0.5118 0.8488 3071335 PK04_107264 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N09 mock treatment 560.0 47.2 0.22 400.0 -127.0 -0.52 -0.2154 -0.3804 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N10 mock treatment 240.0 -273.0 -1.26 360.0 -167.0 -0.69 -1.3766 -0.9594 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N11 compound treatment 640.0 127.0 0.59 520.0 -6.88 -0.03 0.3953 0.6722 3189683 PK04_107265 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N12 compound treatment 480.0 -32.8 -0.15 640.0 113.0 0.47 0.2224 0.454 3189684 PK04_107266 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N13 mock treatment 400.0 -113.0 -0.52 440.0 -86.9 -0.36 -0.6213 -0.9832 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N14 mock treatment 360.0 -153.0 -0.71 440.0 -86.9 -0.36 -0.7518 -0.9505 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N15 compound treatment 520.0 7.21 0.03 360.0 -167.0 -0.69 -0.4625 -0.6721 3071336 PK04_107267 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(o2)c3cccc(c3)C(F)(F)F)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N16 compound treatment 1520.0 1010.0 4.65 1880.0 1350.0 5.57 7.2293 0.996 3189685 PK04_107268 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N17 compound treatment 440.0 -72.8 -0.34 800.0 273.0 1.12 0.5578 0.4751 3189686 PK04_107269 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cc4ccccc4o3)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N18 compound treatment 1480.0 967.0 4.47 840.0 313.0 1.29 4.0698 0.8755 3071337 PK04_107270 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N19 compound treatment 1080.0 567.0 2.62 1240.0 713.0 2.94 3.9288 0.9984 3189687 PK04_107271 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N20 compound treatment 1440.0 927.0 4.28 560.0 33.1 0.14 3.1237 0.7293 3189688 PK04_107272 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N21 compound treatment 960.0 447.0 2.06 840.0 313.0 1.29 2.372 0.9743 3071339 PK04_107273 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N22 compound treatment 1240.0 727.0 3.36 680.0 153.0 0.63 2.8202 0.8255 3189689 PK04_107274 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)c6ccccc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N23 compound treatment 1400.0 887.0 4.1 1400.0 873.0 3.6 5.4396 0.9979 3189690 PK04_107275 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 N24 compound treatment 640.0 127.0 0.59 440.0 -86.9 -0.36 0.1623 0.236 3071341 PK04_107276 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)c5ccccc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O01 compound treatment 600.0 87.2 0.4 760.0 233.0 0.96 0.9637 0.9256 3414059 PK04_107277 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O02 compound treatment 560.0 47.2 0.22 400.0 -127.0 -0.52 -0.2154 -0.3804 3189692 PK04_107278 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O03 compound treatment 1160.0 647.0 2.99 1000.0 473.0 1.95 3.491 0.9785 3414060 PK04_107279 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O04 compound treatment 320.0 -193.0 -0.89 360.0 -167.0 -0.69 -1.1154 -0.9918 3189693 PK04_107280 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O05 compound treatment 560.0 47.2 0.22 640.0 113.0 0.47 0.4836 0.9401 3071393 PK04_107281 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O06 compound treatment 480.0 -32.8 -0.15 520.0 -6.88 -0.03 -0.1271 -0.8251 3189694 PK04_107282 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O07 compound treatment 1480.0 967.0 4.47 1040.0 513.0 2.11 4.6523 0.9416 3189695 PK04_107283 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O08 compound treatment 720.0 207.0 0.96 560.0 33.1 0.14 0.773 0.7999 3071395 PK04_107284 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O09 compound treatment 1880.0 1370.0 6.31 1960.0 1430.0 5.9 8.6377 0.9994 3189696 PK04_107285 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O10 compound treatment 520.0 7.21 0.03 360.0 -167.0 -0.69 -0.4625 -0.6721 3189697 PK04_107286 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O11 mock treatment 480.0 -32.8 -0.15 640.0 113.0 0.47 0.2224 0.454 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O12 mock treatment 480.0 -32.8 -0.15 440.0 -86.9 -0.36 -0.3601 -0.9267 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O13 compound treatment 680.0 167.0 0.77 600.0 73.1 0.3 0.7589 0.9157 3071396 PK04_107287 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O14 compound treatment 560.0 47.2 0.22 400.0 -127.0 -0.52 -0.2154 -0.3804 3187592 PK04_107288 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O15 compound treatment 840.0 327.0 1.51 760.0 233.0 0.96 1.7473 0.9761 3187593 PK04_107289 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O16 compound treatment 520.0 7.21 0.03 440.0 -86.9 -0.36 -0.2295 -0.6385 3071397 PK04_107290 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O17 compound treatment 800.0 287.0 1.33 1320.0 793.0 3.27 3.2477 0.9211 3187594 PK04_107291 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O18 compound treatment 600.0 87.2 0.4 400.0 -127.0 -0.52 -0.0848 -0.1285 3071398 PK04_107292 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O19 compound treatment 800.0 287.0 1.33 920.0 393.0 1.62 2.0827 0.9951 3187595 PK04_107293 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O20 compound treatment 520.0 7.21 0.03 360.0 -167.0 -0.69 -0.4625 -0.6721 3071399 PK04_107294 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O21 compound treatment 560.0 47.2 0.22 640.0 113.0 0.47 0.4836 0.9401 3187594 PK04_107295 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O22 compound treatment 480.0 -32.8 -0.15 320.0 -207.0 -0.85 -0.7096 -0.8199 3187596 PK04_107296 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O23 compound treatment 960.0 447.0 2.06 520.0 -6.88 -0.03 1.4401 0.6973 3187597 PK04_107297 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 O24 compound treatment 560.0 47.2 0.22 360.0 -167.0 -0.69 -0.3319 -0.4603 3071400 PK04_107298 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P01 compound treatment 1080.0 567.0 2.62 840.0 313.0 1.29 2.7638 0.9468 3187598 PK04_107299 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cc3ccccc3o2)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P02 compound treatment 1120.0 607.0 2.8 640.0 113.0 0.47 2.3119 0.8135 3071401 PK04_107300 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P03 compound treatment 360.0 -153.0 -0.71 560.0 33.1 0.14 -0.4023 -0.56 3187599 PK04_107301 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3cccc4ccccc34)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P04 compound treatment 520.0 7.21 0.03 1040.0 513.0 2.11 1.518 0.7182 3187600 PK04_107302 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P05 compound treatment 680.0 167.0 0.77 760.0 233.0 0.96 1.2249 0.9942 3071402 PK04_107303 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P06 compound treatment 920.0 407.0 1.88 1200.0 673.0 2.77 3.2899 0.9821 3187601 PK04_107304 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P07 compound treatment 680.0 167.0 0.77 840.0 313.0 1.29 1.4579 0.9699 3187602 PK04_107305 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P08 compound treatment 1640.0 1130.0 5.2 920.0 393.0 1.62 4.8251 0.8852 3071403 PK04_107306 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P09 compound treatment 680.0 167.0 0.77 560.0 33.1 0.14 0.6424 0.8194 3187603 PK04_107307 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P10 compound treatment 1680.0 1170.0 5.39 1360.0 833.0 3.43 6.2372 0.9762 3187604 PK04_107308 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc(cc4)c5ccccc5)c6cc(OCCCO)ccc6N1C(=O)Cc7ccc(OC)cc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P11 mock treatment 640.0 127.0 0.59 640.0 113.0 0.47 0.7448 0.9934 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P12 mock treatment 520.0 7.21 0.03 360.0 -167.0 -0.69 -0.4625 -0.6721 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P13 compound treatment 480.0 -32.8 -0.15 720.0 193.0 0.8 0.4554 0.5624 3071404 PK04_107309 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2cccc3ccccc23)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P14 compound treatment 2000.0 1490.0 6.87 1240.0 713.0 2.94 6.9325 0.9282 3187605 PK04_107310 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)C4CCCCC4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc(OC)cc6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P15 compound treatment 760.0 247.0 1.14 560.0 33.1 0.14 0.9036 0.786 3187606 PK04_107311 COc1ccc(CC(=O)N2[C@H](C(CC=C)OC(=O)C)[C@@H](N(Cc3ccc(cc3)c4ccccc4)C(=O)c5ccc(C)cc5)c6cc(OCCCO)ccc26)cc1 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P16 compound treatment 440.0 -72.8 -0.34 640.0 113.0 0.47 0.0918 0.1599 3071405 PK04_107312 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)CC(C)C)c4cc(OCCCO)ccc4N1C(=O)Cc5ccc(OC)cc5 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P17 compound treatment 800.0 287.0 1.33 880.0 353.0 1.45 1.9662 0.9989 3187607 PK04_107313 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P18 compound treatment 2640.0 2130.0 9.82 1920.0 1390.0 5.74 11.0025 0.9672 3187608 PK04_107314 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccccc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P19 compound treatment 920.0 407.0 1.88 640.0 113.0 0.47 1.659 0.8564 3187728 PK04_107315 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)Cc6ccc7ccccc7c6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P20 compound treatment 2160.0 1650.0 7.61 2160.0 1630.0 6.73 10.1343 0.9981 3071452 PK04_107316 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)Cc4ccc(OC)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P21 compound treatment 1680.0 1170.0 5.39 1120.0 593.0 2.44 5.5382 0.936 3187729 PK04_107317 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc7ccccc7n6 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P22 compound treatment 1800.0 1290.0 5.94 1320.0 793.0 3.27 6.5125 0.9603 3187730 PK04_107318 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5n4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P23 compound treatment 800.0 287.0 1.33 800.0 273.0 1.12 1.7332 0.9966 3071453 PK04_107319 CC(=O)OC(CC=C)[C@@H]1[C@@H](N(Cc2ccc(cc2)c3ccccc3)C(=O)c4ccc(C)cc4)c5cc(OCCCO)ccc5N1C(=O)c6ccc(cc6)c7ccccc7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.2107 P24 compound treatment 2040.0 1530.0 7.05 1360.0 833.0 3.43 7.4126 0.9452 3187731 PK04_107320 CCOC(=O)C[C@H]1[C@H](OC(=O)Cc2ccc3OCOc3c2)[C@@H](NC(=O)c4ccc5ccccc5c4)c6cc(OCCCO)ccc6N1C(=O)c7ccc8ccccc8n7 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A01 mock treatment 480.0 -37.8 -0.17 600.0 50.1 0.21 0.0225 0.0832 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A02 mock treatment 1080.0 562.0 2.6 680.0 130.0 0.54 2.2144 0.8354 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A03 mock treatment 440.0 -77.8 -0.36 440.0 -110.0 -0.45 -0.5741 -0.9934 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A04 mock treatment 520.0 2.23 0.01 440.0 -110.0 -0.45 -0.3129 -0.6909 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A05 mock treatment 360.0 -158.0 -0.73 480.0 -69.9 -0.29 -0.7188 -0.9176 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A06 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A07 mock treatment 720.0 202.0 0.93 400.0 -150.0 -0.62 0.2235 0.1997 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A08 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A09 mock treatment 320.0 -198.0 -0.91 400.0 -150.0 -0.62 -1.0824 -0.9819 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A10 mock treatment 560.0 42.2 0.19 400.0 -150.0 -0.62 -0.2988 -0.4614 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A11 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A12 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A13 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A14 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A15 mock treatment 560.0 42.2 0.19 400.0 -150.0 -0.62 -0.2988 -0.4614 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A16 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A17 mock treatment 480.0 -37.8 -0.17 600.0 50.1 0.21 0.0225 0.0832 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A18 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A19 mock treatment 440.0 -77.8 -0.36 640.0 90.1 0.37 0.0084 0.0162 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A20 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A21 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A22 mock treatment 640.0 122.0 0.56 920.0 370.0 1.52 1.4768 0.9086 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A23 mock treatment 520.0 2.23 0.01 960.0 410.0 1.69 1.2015 0.7114 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base A24 mock treatment 520.0 2.23 0.01 840.0 290.0 1.19 0.852 0.7132 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B01 mock treatment 240.0 -278.0 -1.28 440.0 -110.0 -0.45 -1.2271 -0.9022 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B02 mock treatment 560.0 42.2 0.19 680.0 130.0 0.54 0.5166 0.9063 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B03 mock treatment 480.0 -37.8 -0.17 600.0 50.1 0.21 0.0225 0.0832 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B04 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B05 mock treatment 560.0 42.2 0.19 320.0 -230.0 -0.95 -0.5318 -0.55 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B06 mock treatment 680.0 162.0 0.75 560.0 10.1 0.04 0.5589 0.7451 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B07 mock treatment 640.0 122.0 0.56 400.0 -150.0 -0.62 -0.0377 -0.045 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B08 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B09 mock treatment 400.0 -118.0 -0.54 600.0 50.1 0.21 -0.2387 -0.4105 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B10 mock treatment 560.0 42.2 0.19 320.0 -230.0 -0.95 -0.5318 -0.55 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B11 mock treatment 800.0 282.0 1.3 680.0 130.0 0.54 1.3002 0.9228 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B12 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B13 mock treatment 640.0 122.0 0.56 600.0 50.1 0.21 0.5448 0.9068 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B14 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B15 mock treatment 360.0 -158.0 -0.73 560.0 10.1 0.04 -0.4858 -0.6658 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B16 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B17 mock treatment 560.0 42.2 0.19 400.0 -150.0 -0.62 -0.2988 -0.4614 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B18 mock treatment 520.0 2.23 0.01 480.0 -69.9 -0.29 -0.1964 -0.6814 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B19 mock treatment 600.0 82.2 0.38 480.0 -69.9 -0.29 0.0647 0.1358 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B20 mock treatment 520.0 2.23 0.01 440.0 -110.0 -0.45 -0.3129 -0.6909 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B21 mock treatment 440.0 -77.8 -0.36 640.0 90.1 0.37 0.0084 0.0162 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B22 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B23 mock treatment 680.0 162.0 0.75 520.0 -29.9 -0.12 0.4424 0.5828 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base B24 mock treatment 680.0 162.0 0.75 680.0 130.0 0.54 0.9084 0.9865 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C01 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C02 mock treatment 480.0 -37.8 -0.17 360.0 -190.0 -0.78 -0.6765 -0.844 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C03 mock treatment 680.0 162.0 0.75 440.0 -110.0 -0.45 0.2094 0.2393 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C04 mock treatment 480.0 -37.8 -0.17 560.0 10.1 0.04 -0.094 -0.5246 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C05 mock treatment 560.0 42.2 0.19 520.0 -29.9 -0.12 0.0506 0.2195 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C06 mock treatment 520.0 2.23 0.01 560.0 10.1 0.04 0.0366 0.8567 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C07 mock treatment 400.0 -118.0 -0.54 720.0 170.0 0.7 0.1108 0.1249 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C08 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C09 mock treatment 400.0 -118.0 -0.54 520.0 -29.9 -0.12 -0.4717 -0.846 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C10 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C11 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C12 mock treatment 680.0 162.0 0.75 760.0 210.0 0.87 1.1414 0.9974 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C13 mock treatment 520.0 2.23 0.01 680.0 130.0 0.54 0.3861 0.7206 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C14 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C15 mock treatment 440.0 -77.8 -0.36 760.0 210.0 0.87 0.3579 0.382 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C16 mock treatment 720.0 202.0 0.93 480.0 -69.9 -0.29 0.4565 0.4672 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C17 mock treatment 560.0 42.2 0.19 520.0 -29.9 -0.12 0.0506 0.2195 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C18 mock treatment 640.0 122.0 0.56 680.0 130.0 0.54 0.7778 0.9997 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C19 mock treatment 560.0 42.2 0.19 560.0 10.1 0.04 0.1671 0.8386 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C20 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C21 mock treatment 600.0 82.2 0.38 680.0 130.0 0.54 0.6472 0.9858 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C22 mock treatment 560.0 42.2 0.19 560.0 10.1 0.04 0.1671 0.8386 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C23 mock treatment 600.0 82.2 0.38 560.0 10.1 0.04 0.2977 0.7796 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base C24 mock treatment 560.0 42.2 0.19 560.0 10.1 0.04 0.1671 0.8386 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D01 mock treatment 560.0 42.2 0.19 400.0 -150.0 -0.62 -0.2988 -0.4614 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D02 mock treatment 360.0 -158.0 -0.73 600.0 50.1 0.21 -0.3693 -0.4878 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D03 mock treatment 600.0 82.2 0.38 560.0 10.1 0.04 0.2977 0.7796 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D04 mock treatment 480.0 -37.8 -0.17 560.0 10.1 0.04 -0.094 -0.5246 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D05 mock treatment 520.0 2.23 0.01 560.0 10.1 0.04 0.0366 0.8567 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D06 mock treatment 480.0 -37.8 -0.17 680.0 130.0 0.54 0.2555 0.4535 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D07 mock treatment 600.0 82.2 0.38 440.0 -110.0 -0.45 -0.0518 -0.0876 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D08 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D09 mock treatment 560.0 42.2 0.19 520.0 -29.9 -0.12 0.0506 0.2195 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D10 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D11 mock treatment 520.0 2.23 0.01 760.0 210.0 0.87 0.619 0.7155 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D12 mock treatment 880.0 362.0 1.67 400.0 -150.0 -0.62 0.7459 0.4184 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D13 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D14 mock treatment 400.0 -118.0 -0.54 760.0 210.0 0.87 0.2273 0.2224 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D15 mock treatment 600.0 82.2 0.38 640.0 90.1 0.37 0.5307 0.9999 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D16 mock treatment 520.0 2.23 0.01 400.0 -150.0 -0.62 -0.4294 -0.6952 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D17 mock treatment 600.0 82.2 0.38 520.0 -29.9 -0.12 0.1812 0.454 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D18 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D19 mock treatment 640.0 122.0 0.56 1000.0 450.0 1.85 1.7098 0.8824 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D20 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D21 mock treatment 520.0 2.23 0.01 720.0 170.0 0.7 0.5026 0.7174 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D22 mock treatment 440.0 -77.8 -0.36 640.0 90.1 0.37 0.0084 0.0162 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D23 mock treatment 600.0 82.2 0.38 440.0 -110.0 -0.45 -0.0518 -0.0876 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base D24 mock treatment 640.0 122.0 0.56 720.0 170.0 0.7 0.8943 0.9943 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E01 mock treatment 640.0 122.0 0.56 440.0 -110.0 -0.45 0.0788 0.109 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E02 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E03 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E04 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E05 mock treatment 520.0 2.23 0.01 440.0 -110.0 -0.45 -0.3129 -0.6909 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E06 mock treatment 520.0 2.23 0.01 640.0 90.1 0.37 0.2696 0.7264 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E07 mock treatment 440.0 -77.8 -0.36 720.0 170.0 0.7 0.2414 0.3066 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E08 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E09 mock treatment 560.0 42.2 0.19 720.0 170.0 0.7 0.6331 0.8708 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E10 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E11 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E12 mock treatment 560.0 42.2 0.19 440.0 -110.0 -0.45 -0.1823 -0.3698 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E13 mock treatment 640.0 122.0 0.56 680.0 130.0 0.54 0.7778 0.9997 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E14 mock treatment 480.0 -37.8 -0.17 440.0 -110.0 -0.45 -0.4435 -0.914 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E15 mock treatment 800.0 282.0 1.3 760.0 210.0 0.87 1.5332 0.9802 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E16 mock treatment 480.0 -37.8 -0.17 800.0 250.0 1.03 0.605 0.5791 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E17 mock treatment 600.0 82.2 0.38 720.0 170.0 0.7 0.7637 0.9586 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E18 mock treatment 440.0 -77.8 -0.36 440.0 -110.0 -0.45 -0.5741 -0.9934 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E19 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E20 mock treatment 480.0 -37.8 -0.17 360.0 -190.0 -0.78 -0.6765 -0.844 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E21 mock treatment 560.0 42.2 0.19 760.0 210.0 0.87 0.7496 0.8453 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E22 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E23 mock treatment 600.0 82.2 0.38 640.0 90.1 0.37 0.5307 0.9999 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base E24 mock treatment 680.0 162.0 0.75 440.0 -110.0 -0.45 0.2094 0.2393 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F01 mock treatment 360.0 -158.0 -0.73 360.0 -190.0 -0.78 -1.0683 -0.9994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F02 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F03 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F04 mock treatment 480.0 -37.8 -0.17 680.0 130.0 0.54 0.2555 0.4535 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F05 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F06 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F07 mock treatment 560.0 42.2 0.19 800.0 250.0 1.03 0.8661 0.8263 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F08 mock treatment 1240.0 722.0 3.33 480.0 -69.9 -0.29 2.1542 0.6436 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F09 mock treatment 640.0 122.0 0.56 640.0 90.1 0.37 0.6613 0.9793 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F10 mock treatment 520.0 2.23 0.01 440.0 -110.0 -0.45 -0.3129 -0.6909 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F11 mock treatment 720.0 202.0 0.93 720.0 170.0 0.7 1.1555 0.99 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F12 mock treatment 400.0 -118.0 -0.54 520.0 -29.9 -0.12 -0.4717 -0.846 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F13 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F14 mock treatment 480.0 -37.8 -0.17 680.0 130.0 0.54 0.2555 0.4535 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F15 mock treatment 600.0 82.2 0.38 720.0 170.0 0.7 0.7637 0.9586 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F16 mock treatment 440.0 -77.8 -0.36 640.0 90.1 0.37 0.0084 0.0162 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F17 mock treatment 600.0 82.2 0.38 680.0 130.0 0.54 0.6472 0.9858 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F18 mock treatment 520.0 2.23 0.01 480.0 -69.9 -0.29 -0.1964 -0.6814 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F19 mock treatment 920.0 402.0 1.86 640.0 90.1 0.37 1.5755 0.8319 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F20 mock treatment 600.0 82.2 0.38 480.0 -69.9 -0.29 0.0647 0.1358 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F21 mock treatment 760.0 242.0 1.12 1040.0 490.0 2.02 2.2181 0.9612 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F22 mock treatment 480.0 -37.8 -0.17 720.0 170.0 0.7 0.372 0.5153 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F23 mock treatment 680.0 162.0 0.75 560.0 10.1 0.04 0.5589 0.7451 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base F24 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G01 mock treatment 520.0 2.23 0.01 360.0 -190.0 -0.78 -0.5459 -0.6977 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G02 mock treatment 400.0 -118.0 -0.54 640.0 90.1 0.37 -0.1222 -0.1857 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G03 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G04 mock treatment 360.0 -158.0 -0.73 680.0 130.0 0.54 -0.1363 -0.1508 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G05 mock treatment 640.0 122.0 0.56 520.0 -29.9 -0.12 0.3118 0.5398 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G06 mock treatment 520.0 2.23 0.01 640.0 90.1 0.37 0.2696 0.7264 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G07 mock treatment 520.0 2.23 0.01 760.0 210.0 0.87 0.619 0.7155 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G08 mock treatment 280.0 -238.0 -1.1 480.0 -69.9 -0.29 -0.98 -0.8634 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G09 mock treatment 480.0 -37.8 -0.17 760.0 210.0 0.87 0.4885 0.5534 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G10 mock treatment 520.0 2.23 0.01 600.0 50.1 0.21 0.1531 0.7415 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G11 mock treatment 600.0 82.2 0.38 720.0 170.0 0.7 0.7637 0.9586 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G12 mock treatment 320.0 -198.0 -0.91 480.0 -69.9 -0.29 -0.8494 -0.8871 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G13 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G14 mock treatment 440.0 -77.8 -0.36 600.0 50.1 0.21 -0.1081 -0.2612 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G15 mock treatment 520.0 2.23 0.01 560.0 10.1 0.04 0.0366 0.8567 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G16 mock treatment 520.0 2.23 0.01 400.0 -150.0 -0.62 -0.4294 -0.6952 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G17 mock treatment 360.0 -158.0 -0.73 520.0 -29.9 -0.12 -0.6023 -0.8152 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G18 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G19 mock treatment 400.0 -118.0 -0.54 400.0 -150.0 -0.62 -0.8212 -0.998 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G20 mock treatment 480.0 -37.8 -0.17 440.0 -110.0 -0.45 -0.4435 -0.914 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G21 mock treatment 400.0 -118.0 -0.54 520.0 -29.9 -0.12 -0.4717 -0.846 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G22 mock treatment 600.0 82.2 0.38 1000.0 450.0 1.85 1.5792 0.8346 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G23 mock treatment 400.0 -118.0 -0.54 560.0 10.1 0.04 -0.3552 -0.6514 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base G24 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H01 mock treatment 560.0 42.2 0.19 400.0 -150.0 -0.62 -0.2988 -0.4614 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H02 mock treatment 360.0 -158.0 -0.73 360.0 -190.0 -0.78 -1.0683 -0.9994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H03 mock treatment 560.0 42.2 0.19 560.0 10.1 0.04 0.1671 0.8386 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H04 mock treatment 400.0 -118.0 -0.54 320.0 -230.0 -0.95 -1.0542 -0.9653 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H05 mock treatment 680.0 162.0 0.75 480.0 -69.9 -0.29 0.3259 0.4061 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H06 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H07 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H08 mock treatment 240.0 -278.0 -1.28 720.0 170.0 0.7 -0.4116 -0.2817 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H09 mock treatment 480.0 -37.8 -0.17 440.0 -110.0 -0.45 -0.4435 -0.914 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H10 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H11 mock treatment 400.0 -118.0 -0.54 720.0 170.0 0.7 0.1108 0.1249 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H12 mock treatment 680.0 162.0 0.75 720.0 170.0 0.7 1.0249 0.9994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H13 mock treatment 560.0 42.2 0.19 960.0 410.0 1.69 1.3321 0.7835 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H14 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H15 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H16 mock treatment 480.0 -37.8 -0.17 440.0 -110.0 -0.45 -0.4435 -0.914 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H17 mock treatment 600.0 82.2 0.38 520.0 -29.9 -0.12 0.1812 0.454 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H18 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H19 mock treatment 480.0 -37.8 -0.17 680.0 130.0 0.54 0.2555 0.4535 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H20 mock treatment 520.0 2.23 0.01 400.0 -150.0 -0.62 -0.4294 -0.6952 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H21 mock treatment 720.0 202.0 0.93 600.0 50.1 0.21 0.806 0.8429 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H22 mock treatment 320.0 -198.0 -0.91 480.0 -69.9 -0.29 -0.8494 -0.8871 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H23 mock treatment 520.0 2.23 0.01 880.0 330.0 1.36 0.9685 0.7124 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base H24 mock treatment 360.0 -158.0 -0.73 720.0 170.0 0.7 -0.0198 -0.0196 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I01 mock treatment 600.0 82.2 0.38 480.0 -69.9 -0.29 0.0647 0.1358 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I02 mock treatment 680.0 162.0 0.75 480.0 -69.9 -0.29 0.3259 0.4061 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I03 mock treatment 640.0 122.0 0.56 640.0 90.1 0.37 0.6613 0.9793 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I04 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I05 mock treatment 600.0 82.2 0.38 440.0 -110.0 -0.45 -0.0518 -0.0876 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I06 mock treatment 560.0 42.2 0.19 560.0 10.1 0.04 0.1671 0.8386 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I07 mock treatment 520.0 2.23 0.01 600.0 50.1 0.21 0.1531 0.7415 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I08 mock treatment 520.0 2.23 0.01 480.0 -69.9 -0.29 -0.1964 -0.6814 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I09 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I10 mock treatment 400.0 -118.0 -0.54 440.0 -110.0 -0.45 -0.7047 -0.9959 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I11 mock treatment 480.0 -37.8 -0.17 560.0 10.1 0.04 -0.094 -0.5246 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I12 mock treatment 640.0 122.0 0.56 440.0 -110.0 -0.45 0.0788 0.109 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I13 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I14 mock treatment 640.0 122.0 0.56 480.0 -69.9 -0.29 0.1953 0.3083 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I15 mock treatment 720.0 202.0 0.93 680.0 130.0 0.54 1.039 0.9652 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I16 mock treatment 520.0 2.23 0.01 840.0 290.0 1.19 0.852 0.7132 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I17 mock treatment 920.0 402.0 1.86 640.0 90.1 0.37 1.5755 0.8319 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I18 mock treatment 680.0 162.0 0.75 400.0 -150.0 -0.62 0.0929 0.0957 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I19 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I20 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I21 mock treatment 440.0 -77.8 -0.36 720.0 170.0 0.7 0.2414 0.3066 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I22 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I23 mock treatment 640.0 122.0 0.56 800.0 250.0 1.03 1.1273 0.9599 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base I24 mock treatment 680.0 162.0 0.75 640.0 90.1 0.37 0.7919 0.9475 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J01 mock treatment 320.0 -198.0 -0.91 760.0 210.0 0.87 -0.0339 -0.027 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J02 mock treatment 840.0 322.0 1.49 560.0 10.1 0.04 1.0813 0.7265 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J03 mock treatment 520.0 2.23 0.01 560.0 10.1 0.04 0.0366 0.8567 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J04 mock treatment 600.0 82.2 0.38 480.0 -69.9 -0.29 0.0647 0.1358 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J05 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J06 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J07 mock treatment 400.0 -118.0 -0.54 360.0 -190.0 -0.78 -0.9377 -0.9842 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J08 mock treatment 320.0 -198.0 -0.91 400.0 -150.0 -0.62 -1.0824 -0.9819 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J09 mock treatment 600.0 82.2 0.38 760.0 210.0 0.87 0.8802 0.9316 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J10 mock treatment 440.0 -77.8 -0.36 600.0 50.1 0.21 -0.1081 -0.2612 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J11 mock treatment 760.0 242.0 1.12 520.0 -29.9 -0.12 0.7036 0.6253 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J12 mock treatment 440.0 -77.8 -0.36 720.0 170.0 0.7 0.2414 0.3066 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J13 mock treatment 680.0 162.0 0.75 480.0 -69.9 -0.29 0.3259 0.4061 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J14 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J15 mock treatment 680.0 162.0 0.75 800.0 250.0 1.03 1.2579 0.9878 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J16 mock treatment 480.0 -37.8 -0.17 880.0 330.0 1.36 0.838 0.6114 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J17 mock treatment 520.0 2.23 0.01 760.0 210.0 0.87 0.619 0.7155 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J18 mock treatment 440.0 -77.8 -0.36 640.0 90.1 0.37 0.0084 0.0162 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J19 mock treatment 600.0 82.2 0.38 840.0 290.0 1.19 1.1132 0.8881 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J20 mock treatment 480.0 -37.8 -0.17 720.0 170.0 0.7 0.372 0.5153 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J21 mock treatment 680.0 162.0 0.75 600.0 50.1 0.21 0.6754 0.8694 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J22 mock treatment 480.0 -37.8 -0.17 600.0 50.1 0.21 0.0225 0.0832 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J23 mock treatment 680.0 162.0 0.75 720.0 170.0 0.7 1.0249 0.9994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base J24 mock treatment 400.0 -118.0 -0.54 600.0 50.1 0.21 -0.2387 -0.4105 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K01 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K02 mock treatment 400.0 -118.0 -0.54 440.0 -110.0 -0.45 -0.7047 -0.9959 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K03 mock treatment 560.0 42.2 0.19 520.0 -29.9 -0.12 0.0506 0.2195 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K04 mock treatment 400.0 -118.0 -0.54 520.0 -29.9 -0.12 -0.4717 -0.846 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K05 mock treatment 360.0 -158.0 -0.73 480.0 -69.9 -0.29 -0.7188 -0.9176 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K06 mock treatment 480.0 -37.8 -0.17 440.0 -110.0 -0.45 -0.4435 -0.914 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K07 mock treatment 360.0 -158.0 -0.73 480.0 -69.9 -0.29 -0.7188 -0.9176 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K08 mock treatment 480.0 -37.8 -0.17 440.0 -110.0 -0.45 -0.4435 -0.914 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K09 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K10 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K11 mock treatment 520.0 2.23 0.01 600.0 50.1 0.21 0.1531 0.7415 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K12 mock treatment 520.0 2.23 0.01 440.0 -110.0 -0.45 -0.3129 -0.6909 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K13 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K14 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K15 mock treatment 520.0 2.23 0.01 640.0 90.1 0.37 0.2696 0.7264 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K16 mock treatment 400.0 -118.0 -0.54 600.0 50.1 0.21 -0.2387 -0.4105 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K17 mock treatment 640.0 122.0 0.56 400.0 -150.0 -0.62 -0.0377 -0.045 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K18 mock treatment 800.0 282.0 1.3 440.0 -110.0 -0.45 0.6012 0.4358 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K19 mock treatment 600.0 82.2 0.38 560.0 10.1 0.04 0.2977 0.7796 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K20 mock treatment 400.0 -118.0 -0.54 440.0 -110.0 -0.45 -0.7047 -0.9959 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K21 mock treatment 440.0 -77.8 -0.36 680.0 130.0 0.54 0.1249 0.1936 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K22 mock treatment 520.0 2.23 0.01 400.0 -150.0 -0.62 -0.4294 -0.6952 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K23 mock treatment 480.0 -37.8 -0.17 520.0 -29.9 -0.12 -0.2105 -0.9856 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base K24 mock treatment 440.0 -77.8 -0.36 360.0 -190.0 -0.78 -0.8071 -0.9376 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L01 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L02 mock treatment 400.0 -118.0 -0.54 640.0 90.1 0.37 -0.1222 -0.1857 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L03 mock treatment 440.0 -77.8 -0.36 800.0 250.0 1.03 0.4744 0.4349 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L04 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L05 mock treatment 480.0 -37.8 -0.17 680.0 130.0 0.54 0.2555 0.4535 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L06 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L07 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L08 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L09 mock treatment 720.0 202.0 0.93 600.0 50.1 0.21 0.806 0.8429 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L10 mock treatment 440.0 -77.8 -0.36 320.0 -230.0 -0.95 -0.9236 -0.9119 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L11 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L12 mock treatment 560.0 42.2 0.19 360.0 -190.0 -0.78 -0.4153 -0.5151 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L13 mock treatment 600.0 82.2 0.38 680.0 130.0 0.54 0.6472 0.9858 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L14 mock treatment 520.0 2.23 0.01 360.0 -190.0 -0.78 -0.5459 -0.6977 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L15 mock treatment 600.0 82.2 0.38 520.0 -29.9 -0.12 0.1812 0.454 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L16 mock treatment 600.0 82.2 0.38 600.0 50.1 0.21 0.4142 0.9588 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L17 mock treatment 440.0 -77.8 -0.36 400.0 -150.0 -0.62 -0.6906 -0.9667 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L18 mock treatment 360.0 -158.0 -0.73 400.0 -150.0 -0.62 -0.9518 -0.9966 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L19 mock treatment 600.0 82.2 0.38 640.0 90.1 0.37 0.5307 0.9999 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L20 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L21 mock treatment 600.0 82.2 0.38 1200.0 650.0 2.68 2.1617 0.7994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L22 mock treatment 440.0 -77.8 -0.36 640.0 90.1 0.37 0.0084 0.0162 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L23 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base L24 mock treatment 480.0 -37.8 -0.17 400.0 -150.0 -0.62 -0.56 -0.8727 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M01 mock treatment 520.0 2.23 0.01 400.0 -150.0 -0.62 -0.4294 -0.6952 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M02 mock treatment 600.0 82.2 0.38 400.0 -150.0 -0.62 -0.1683 -0.2321 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M03 mock treatment 600.0 82.2 0.38 480.0 -69.9 -0.29 0.0647 0.1358 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M04 mock treatment 400.0 -118.0 -0.54 400.0 -150.0 -0.62 -0.8212 -0.998 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M05 mock treatment 400.0 -118.0 -0.54 1000.0 450.0 1.85 0.9263 0.4795 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M06 mock treatment 640.0 122.0 0.56 480.0 -69.9 -0.29 0.1953 0.3083 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M07 mock treatment 400.0 -118.0 -0.54 360.0 -190.0 -0.78 -0.9377 -0.9842 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M08 mock treatment 360.0 -158.0 -0.73 520.0 -29.9 -0.12 -0.6023 -0.8152 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M09 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M10 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M11 mock treatment 480.0 -37.8 -0.17 840.0 290.0 1.19 0.7215 0.5976 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M12 mock treatment 240.0 -278.0 -1.28 560.0 10.1 0.04 -0.8776 -0.6839 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M13 mock treatment 680.0 162.0 0.75 640.0 90.1 0.37 0.7919 0.9475 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M14 mock treatment 440.0 -77.8 -0.36 400.0 -150.0 -0.62 -0.6906 -0.9667 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M15 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M16 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M17 mock treatment 480.0 -37.8 -0.17 400.0 -150.0 -0.62 -0.56 -0.8727 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M18 mock treatment 360.0 -158.0 -0.73 520.0 -29.9 -0.12 -0.6023 -0.8152 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M19 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M20 mock treatment 400.0 -118.0 -0.54 360.0 -190.0 -0.78 -0.9377 -0.9842 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M21 mock treatment 360.0 -158.0 -0.73 480.0 -69.9 -0.29 -0.7188 -0.9176 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M22 mock treatment 360.0 -158.0 -0.73 600.0 50.1 0.21 -0.3693 -0.4878 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M23 mock treatment 520.0 2.23 0.01 680.0 130.0 0.54 0.3861 0.7206 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base M24 mock treatment 360.0 -158.0 -0.73 280.0 -270.0 -1.11 -1.3013 -0.979 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N01 mock treatment 800.0 282.0 1.3 400.0 -150.0 -0.62 0.4847 0.3361 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N02 mock treatment 400.0 -118.0 -0.54 640.0 90.1 0.37 -0.1222 -0.1857 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N03 mock treatment 520.0 2.23 0.01 320.0 -230.0 -0.95 -0.6624 -0.6994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N04 mock treatment 440.0 -77.8 -0.36 480.0 -69.9 -0.29 -0.4576 -0.994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N05 mock treatment 600.0 82.2 0.38 520.0 -29.9 -0.12 0.1812 0.454 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N06 mock treatment 640.0 122.0 0.56 600.0 50.1 0.21 0.5448 0.9068 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N07 mock treatment 320.0 -198.0 -0.91 480.0 -69.9 -0.29 -0.8494 -0.8871 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N08 mock treatment 520.0 2.23 0.01 320.0 -230.0 -0.95 -0.6624 -0.6994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N09 mock treatment 560.0 42.2 0.19 600.0 50.1 0.21 0.2836 0.9996 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N10 mock treatment 280.0 -238.0 -1.1 520.0 -29.9 -0.12 -0.8635 -0.7816 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N11 mock treatment 560.0 42.2 0.19 480.0 -69.9 -0.29 -0.0658 -0.1893 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N12 mock treatment 520.0 2.23 0.01 480.0 -69.9 -0.29 -0.1964 -0.6814 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N13 mock treatment 480.0 -37.8 -0.17 560.0 10.1 0.04 -0.094 -0.5246 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N14 mock treatment 720.0 202.0 0.93 520.0 -29.9 -0.12 0.573 0.6084 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N15 mock treatment 560.0 42.2 0.19 720.0 170.0 0.7 0.6331 0.8708 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N16 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N17 mock treatment 480.0 -37.8 -0.17 600.0 50.1 0.21 0.0225 0.0832 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N18 mock treatment 400.0 -118.0 -0.54 560.0 10.1 0.04 -0.3552 -0.6514 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N19 mock treatment 400.0 -118.0 -0.54 480.0 -69.9 -0.29 -0.5882 -0.9559 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N20 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N21 mock treatment 520.0 2.23 0.01 640.0 90.1 0.37 0.2696 0.7264 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N22 mock treatment 360.0 -158.0 -0.73 760.0 210.0 0.87 0.0967 0.0855 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N23 mock treatment 560.0 42.2 0.19 720.0 170.0 0.7 0.6331 0.8708 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base N24 mock treatment 520.0 2.23 0.01 400.0 -150.0 -0.62 -0.4294 -0.6952 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O01 mock treatment 640.0 122.0 0.56 520.0 -29.9 -0.12 0.3118 0.5398 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O02 mock treatment 640.0 122.0 0.56 480.0 -69.9 -0.29 0.1953 0.3083 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O03 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O04 mock treatment 400.0 -118.0 -0.54 320.0 -230.0 -0.95 -1.0542 -0.9653 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O05 mock treatment 640.0 122.0 0.56 640.0 90.1 0.37 0.6613 0.9793 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O06 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O07 mock treatment 520.0 2.23 0.01 560.0 10.1 0.04 0.0366 0.8567 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O08 mock treatment 600.0 82.2 0.38 440.0 -110.0 -0.45 -0.0518 -0.0876 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O09 mock treatment 520.0 2.23 0.01 720.0 170.0 0.7 0.5026 0.7174 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O10 mock treatment 360.0 -158.0 -0.73 480.0 -69.9 -0.29 -0.7188 -0.9176 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O11 mock treatment 840.0 322.0 1.49 600.0 50.1 0.21 1.1978 0.7975 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O12 mock treatment 560.0 42.2 0.19 640.0 90.1 0.37 0.4001 0.9549 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O13 mock treatment 360.0 -158.0 -0.73 560.0 10.1 0.04 -0.4858 -0.6658 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O14 mock treatment 400.0 -118.0 -0.54 320.0 -230.0 -0.95 -1.0542 -0.9653 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O15 mock treatment 480.0 -37.8 -0.17 400.0 -150.0 -0.62 -0.56 -0.8727 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O16 mock treatment 480.0 -37.8 -0.17 400.0 -150.0 -0.62 -0.56 -0.8727 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O17 mock treatment 640.0 122.0 0.56 840.0 290.0 1.19 1.2438 0.9414 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O18 mock treatment 640.0 122.0 0.56 520.0 -29.9 -0.12 0.3118 0.5398 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O19 mock treatment 520.0 2.23 0.01 640.0 90.1 0.37 0.2696 0.7264 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O20 mock treatment 480.0 -37.8 -0.17 480.0 -69.9 -0.29 -0.327 -0.9711 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O21 mock treatment 560.0 42.2 0.19 800.0 250.0 1.03 0.8661 0.8263 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O22 mock treatment 480.0 -37.8 -0.17 920.0 370.0 1.52 0.9545 0.6221 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O23 mock treatment 680.0 162.0 0.75 720.0 170.0 0.7 1.0249 0.9994 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base O24 mock treatment 680.0 162.0 0.75 440.0 -110.0 -0.45 0.2094 0.2393 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P01 mock treatment 400.0 -118.0 -0.54 320.0 -230.0 -0.95 -1.0542 -0.9653 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P02 mock treatment 560.0 42.2 0.19 440.0 -110.0 -0.45 -0.1823 -0.3698 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P03 mock treatment 680.0 162.0 0.75 640.0 90.1 0.37 0.7919 0.9475 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P04 mock treatment 440.0 -77.8 -0.36 520.0 -29.9 -0.12 -0.3411 -0.8985 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P05 mock treatment 680.0 162.0 0.75 520.0 -29.9 -0.12 0.4424 0.5828 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P06 mock treatment 600.0 82.2 0.38 360.0 -190.0 -0.78 -0.2848 -0.3274 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P07 mock treatment 720.0 202.0 0.93 600.0 50.1 0.21 0.806 0.8429 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P08 mock treatment 480.0 -37.8 -0.17 680.0 130.0 0.54 0.2555 0.4535 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P09 mock treatment 600.0 82.2 0.38 600.0 50.1 0.21 0.4142 0.9588 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P10 mock treatment 560.0 42.2 0.19 520.0 -29.9 -0.12 0.0506 0.2195 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P11 mock treatment 760.0 242.0 1.12 600.0 50.1 0.21 0.9366 0.8236 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P12 mock treatment 640.0 122.0 0.56 400.0 -150.0 -0.62 -0.0377 -0.045 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P13 mock treatment 920.0 402.0 1.86 680.0 130.0 0.54 1.692 0.8754 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P14 mock treatment 520.0 2.23 0.01 520.0 -29.9 -0.12 -0.0799 -0.6459 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P15 mock treatment 440.0 -77.8 -0.36 440.0 -110.0 -0.45 -0.5741 -0.9934 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P16 mock treatment 560.0 42.2 0.19 400.0 -150.0 -0.62 -0.2988 -0.4614 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P17 mock treatment 840.0 322.0 1.49 720.0 170.0 0.7 1.5473 0.9409 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P18 mock treatment 600.0 82.2 0.38 680.0 130.0 0.54 0.6472 0.9858 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P19 mock treatment 440.0 -77.8 -0.36 1120.0 570.0 2.35 1.4064 0.5921 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P20 mock treatment 520.0 2.23 0.01 440.0 -110.0 -0.45 -0.3129 -0.6909 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P21 mock treatment 760.0 242.0 1.12 640.0 90.1 0.37 1.0531 0.8937 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P22 mock treatment 480.0 -37.8 -0.17 640.0 90.1 0.37 0.139 0.339 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P23 mock treatment 1080.0 562.0 2.6 840.0 290.0 1.19 2.6804 0.938 1029.0013 LacZReporter(1029.0013) CREBReporterAssay 1029.0013.Base P24 mock treatment 440.0 -77.8 -0.36 560.0 10.1 0.04 -0.2246 -0.6214